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Phosphofructokinase 2
|EC number
|CAS number
|IntEnz view
|BRENDA entry
|NiceZyme view
|KEGG entry
|metabolic pathway
|PDB structures
|RCSB PDB PDBe PDBsum
|Gene Ontology
|AmiGO / EGO
|fructose-2,6-bisphosphate 2-phosphatase
|EC number
|CAS number
|IntEnz view
|BRENDA entry
|NiceZyme view
|KEGG entry
|metabolic pathway
|PDB structures
|RCSB PDB PDBe PDBsum
|Gene Ontology
|AmiGO / EGO
Structure of PFK2. Shown: kinase domain (cyan) and the phosphatase domain (green).
Phosphofructokinase 2 (PFK2) or fructose bisphosphatase 2 (FBPase2), is an enzyme responsible for regulating the rates of glycolysis and gluconeogenesis in the human body. It is a homodimer of 55 kDa subunits arranged in a head-to-head fashion, with each polypeptide chain consisting of independent kinase and phosphatase domain. When Ser-32 of the bifunctional protein is phosphorylated, the negative charge causes the conformation change of the enzyme to favor the FBPase2 activity; otherwise, PFK2 activity is favored.[1] The PFK2 domain is closely related to the superfamily of mononucleotide binding proteins including adenylate cyclase, whereas that of FBPase2 is related to a family of proteins that include phosphoglycerate mutases.
The monomers of the bifunctional protein are clearly divided into two functional domains. The kinase domain is located on the N-terminal.[2] It consists of a central six-stranded β sheet, with five parallel strands and an antiparallel edge strand, surrounded by seven α helices.[3] The domain contains nucleotide-binding fold (nbf) at the C-terminal end of the first β-strand,[4] and thus resembles the structure of adenylate kinase.
On the other hand, the phosphatase domain is located on the C-terminal.[5] It resembles the family of proteins that include phosphoglycerate mutases (PGMs) and acid phosphatases.[6] The domain has a mixed α/ β structure, with a six-stranded central β sheet, plus an additional α-helical subdomain that covers the presumed active site of the molecule.[3] Finally, N-terminal region modulates PFK2 and FBPase2 activities, and stabilizes the dimer form of the enzyme.[6][7]
When glucose level is low, glucagon is released into the bloodstream, triggering a cAMP signal cascade. In the liver Protein kinase A inactivates the PFK-2 domain of the bifunctional enzyme via phosphorylation, however this does not occur in skeletal muscle. The F-2,6-BPase domain is then activated which lowers fructose 2,6-bisphosphate (F-2,6-BP) levels. Because F-2,6-BP normally stimulates phosphofructokinase-1(PFK1), the decrease in its concentration leads to the inhibition of glycolysis and the stimulation of gluconeogenesis.[8]
On the other hand, when the glucose level increases, the level of fructose 6-phosphate (F6P) subsequently rises and the molecule stimulates phosphoprotein phosphatase-1, which removes phosphoryl group from the bifunctional protein. So PFK2 domain is activated and the kinase catalyzes the formation of F-2,6-BP. Thus, glycolysis is stimulated and gluconeogenesis is inhibited.
The allosteric regulation of PFK2 is very similar to the regulation of PFK1.[9] High levels of AMP or phosphate group signifies a low energy state and thus stimulates PFK2. On the other hand, a high concentration of phosphoenolpyruvate(PEP) and citrate signifies that there is a high level of biosynthetic precursor and hence inhibits PFK2. However, unlike PFK1, PFK2 is not affected by the ATP concentration.
Glucagon inhibits PFK2 by activating Protein Kinase A (PKA), which phosphorylates the PFK2 complex and causes its FBPase activity to be favored; via PKA and PFK2/FBP, glucagon decreases [F-2,6-BP], which inhibits glycolysis by allosteric inhibition of PFK1. Insulin activates PFK2 by activating protein phosphatase, which dephosphorylates the PFK-2 complex and causes its PFK2 activity to be favored; via Protein Phosphatase and PFK2, insulin increases [F-2,6-BP], which activates glycolysis by allosteric activation of PFK1, signalling an abundance of glucose
Reaction mechanism
PFK2 is likely to catalyze the "simple" transfer of γ-phosphoryl group of ATP onto the hydroxyl present on C-2 of fructose-6-phosphate. Yet, the formation of fructose 2,6-bisphosphate could theoretically occur by a variety of mechanisms, including the intermediary formation of Fructose-6-phosphate 2-pyrophosphate.[9]
The hydrolysis of fructose 2,6-biphosphate is likely to follow the below steps:[10]
- Histidine acts as a nucleophile and attacks the 2-phosphate of F-2,6-BP
- The stabilization of pentacoordinated transition state by several salt bridges and hydrogen bonding.
- The breakdown of the transition state and the release of F6P.
- Histidine increases the nucleophilicity of water, which attacks phosphohistidine, generating phosphate and newly protonated histidine.
Clinical significance
The Pfkfb2 gene encoding PFK2/FBPase2 protein is linked to the predisposition to schizophrenia.[11] Furthermore, the control of PFK2/FBPase2 activity was found to be linked to heart functioning and the control against hypoxia.[12]
Five mammalian isozymes of the protein have been reported to date, difference rising by either the transcription of different enzymes or alternative splicing.[13][14][15]The isozymes differ radically in their regulation and the discussions above are based on liver isozyme.[3]
Humans genes encoding proteins possessing phosphofructokinase 2 activity include:
- ↑ Kurland IJ, el-Maghrabi MR, Correia JJ, Pilkis SJ (March 1992). "Rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Properties of phospho- and dephospho- forms and of two mutants in which Ser32 has been changed by site-directed mutagenesis". J. Biol. Chem. 267 (7): 4416–23. PMID 1339450.
- ↑ Kurland I, Chapman B, Lee YH, Pilkis S (August 1995). "Evolutionary reengineering of the phosphofructokinase active site: ARG-104 does not stabilize the transition state in 6-phosphofructo-2-kinase". Biochem. Biophys. Res. Commun. 213 (2): 663–72. doi:10.1006/bbrc.1995.2183. PMID 7646523.
- 1 2 3 Hasemann CA, Istvan ES, Uyeda K, Deisenhofer J (September 1996). "The crystal structure of the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase reveals distinct domain homologies". Structure. 4 (9): 1017–29. doi:10.1016/S0969-2126(96)00109-8. PMID 8805587.
- ↑ Walker JE, Saraste M, Runswick MJ, Gay NJ (1982). "Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold". EMBO J. 1 (8): 945–51. PMC 553140. PMID 6329717.
- ↑ Li L, Lin K, Pilkis J, Correia JJ, Pilkis SJ (October 1992). "Hepatic 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. The role of surface loop basic residues in substrate binding to the fructose-2,6-bisphosphatase domain". J. Biol. Chem. 267 (30): 21588–94. PMID 1328239.
- 1 2 Stryer, Lubert; Berg, Jeremy Mark; Tymoczko, John L. (2008). "The Balance Between Glycolysis and Gluconeogenesis in the Liver Is Sensitive to Blood-Glucose Concentration". Biochemistry (Looseleaf). San Francisco: W. H. Freeman. pp. 466–467. ISBN 1-4292-3502-0.
- ↑ Tominaga N, Minami Y, Sakakibara R, Uyeda K (July 1993). "Significance of the amino terminus of rat testis fructose-6-phosphate, 2-kinase:fructose-2,6-bisphosphatase". J. Biol. Chem. 268 (21): 15951–7. PMID 8393455.
- ↑ Pilkis SJ, Claus TH, Kurland IJ, Lange AJ (1995). "6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: a metabolic signaling enzyme". Annu. Rev. Biochem. 64: 799–835. doi:10.1146/annurev.bi.64.070195.004055. PMID 7574501.
- 1 2 Van Schaftingen E, Hers HG (August 1981). "Phosphofructokinase 2: the enzyme that forms fructose 2,6-bisphosphate from fructose 6-phosphate and ATP". Biochem. Biophys. Res. Commun. 101 (3): 1078–84. doi:10.1016/0006-291X(81)91859-3. PMID 6458291.
- ↑ Lin K, Li L, Correia JJ, Pilkis SJ (April 1992). "Glu327 is part of a catalytic triad in rat liver fructose-2,6-bisphosphatase". J. Biol. Chem. 267 (10): 6556–62. PMID 1313012.
- ↑ Stone WS, Faraone SV, Su J, Tarbox SI, Van Eerdewegh P, Tsuang MT (May 2004). "Evidence for linkage between regulatory enzymes in glycolysis and schizophrenia in a multiplex sample". Am. J. Med. Genet. B Neuropsychiatr. Genet. 127B (1): 5–10. doi:10.1002/ajmg.b.20132. PMID 15108172.
- ↑ Wang Q, Donthi RV, Wang J, Lange AJ, Watson LJ, Jones SP, Epstein PN (June 2008). "Cardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxia". Am. J. Physiol. Heart Circ. Physiol. 294 (6): H2889–97. doi:10.1152/ajpheart.91501.2007. PMID 18456722.
- ↑ Darville MI, Crepin KM, Hue L, Rousseau GG (September 1989). "5' flanking sequence and structure of a gene encoding rat 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase". Proc. Natl. Acad. Sci. U.S.A. 86 (17): 6543–7. doi:10.1073/pnas.86.17.6543. PMC 297880. PMID 2549541.
- ↑ Tsuchiya Y, Uyeda K (May 1994). "Bovine heart fructose 6-P,2-kinase:fructose 2,6-bisphosphatase mRNA and gene structure". Arch. Biochem. Biophys. 310 (2): 467–74. doi:10.1006/abbi.1994.1194. PMID 8179334.
- ↑ Sakata J, Abe Y, Uyeda K (August 1991). "Molecular cloning of the DNA and expression and characterization of rat testes fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase". J. Biol. Chem. 266 (24): 15764–70. PMID 1651918.
Further reading
- Rider MH, Bertrand L, Vertommen D, Michels PA, Rousseau GG, Hue L (August 2004). "6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis". Biochem. J. 381 (Pt 3): 561–79. doi:10.1042/BJ20040752. PMC 1133864. PMID 15170386.
External links
- Fructose 2,6-bisphosphatase at the US National Library of Medicine Medical Subject Headings (MeSH)
- 6-phosphofructokinase of Arabidopsis thaliana at genome.jp


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From school runs to grocery trips to long drives, the Innova is a drive designed to do all of it, and more. An elegant, ergonomic design, coupled with a comfortable and spacious interior, a sterling VVT-i engine and advanced safety features combine to provide you with the perfect drive, for all situations.
Fusing elegant sophistication with a powerful presence, the Innova's premium comfort and outstanding performance contribute to fulfilling family times.
The front headlights gives more elegant touches for exterior design to provide the car with stunning view.
Appropriate spacious interior for 8 passengers that provide comfort and relax.
The spacious cabin can be quickly rearranged to accommodate changing combinations of people and gear. To expand the luggage space to accommodate big or long loads, the second row seats tumble.
Tables integrated into the front seatbacks can hold laptops, drinks and other items.
This convenient box features integrated air conditioning vents to keep drinks stored inside cool or warm.
The clear blue illumination integrated into the overhead console exudes a modern and luxurious feel. It also features dimming control.
The easy-to-read meters and a 4.2-inch color TFT (Thin Film Transistor) multi-information display provide the driver with vital vehicle information at a glance. An Eco Driving Indicator supports eco driving.
The highly efficient system maintains a comfortable cabin temperature, and at the same time contributes to the excellent fuel economy.
Engine featuring with Dual VVT-i (Variable Valve Timing – Intelligent) that balances the delivery of free-flowing power for agile responsive sports driving, with excellent fuel efficiency.
A super intelligent 6-speed automatic transmission produces outstanding driving performance and fuel efficiency.
The front and rear suspension is optimized to provide excellent stability and control, with a flat smooth ride.
Allows the driver to select between Eco Mode to help optimize economy and Power Mode to enhance acceleration to suit the driving conditions.
Comprised of a high integrity cabin with front and rear crumple zones that help absorb impact energy in a collision.
To help reduce the impact to the passengers in a collision, the car is equipped with 3 SRS airbags on front.
ABS helps to prevent the wheels from locking up when braking on slippery roads, or during sudden braking. EBD optimizes the distribution of braking force in various driving conditions
Engine & Transmission
Audio System

subset: commoncrawl


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Travel is the New Shopping: Indie Brand Parachute Launches a Hotel
When your product is mainly sold online, how do you counteract the inability for customers to touch and feel your goods? Parachute, maker of bedding and bath textiles, has created Parachute Hotel, an immersive experience in the form of a gorgeous penthouse situated above their Venice, California showroom.
The 2,200 square foot space was designed by Scott Horne and Peter Dolkas and outfitted with "like-minded vendors, makers and local friends of the brand," said Horne. (If you're coveting something in the penthouse, here's their full list of partners.)
Not only can you book a stay for your vacation (it sleeps up to four), but the penthouse is available for events, photoshoots, workshops, even dinner parties. "We wanted to create a space that would feel comfortable not only for a group of thirty, but for a couple looking to relax on vacation," said Ariel Kaye, Founder and CEO of Parachute.
Just a week ago, West Elm announced their boutique hotels will start opening in cities like Detroit and Savannah in 2018.
See more of Parachute Hotel, which starts taking reservations today, below.


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Linda Cardellini
After skipping a week of devoting an article to one of the many women I love, I'm bringing the heat with Ms.Cardellini. Now that Billy has given up writing to his one true love, it is essential I stay strong and continue to express my devotion. Cardellini is a first ballot hall of famer in my heart. She earned the status back in 1998 when she had a guest stint on Boy Meets World. As a 90s kid there was no better couple than Cory and Topanga. They were the people who introduced me to the idea of love. A symbol for hopeless romantics, anyone who came in the way of their love would be instantly despised and petitioned to be stoned to death. Or so I thought, until Cardellini's Lauren turned my world upside down. She played a snow bunny who worked at the ski resort John Adams High was having their senior trip. Not sure how this trip ever got approved by Feeny. I'm terrible at skiing, but Lauren made me want to move to the mountains. Cory had a broken leg and could not go ski with his classmates, which left him alone with Lauren for most of the day. As they grew closer I wanted to scream at Cor, "Noooooooo!!!!! Don't disrespect Topanga. Instead, I was mesmerized by Cardellini and found myself rooting for Cory to pick her. It was a confusing time.
After Boy Meets World and because of her successful guest stint, Cardellini was cast as the lead in the short-lived and much beloved Freaks and Geeks. The show is remembered for launching the careers of James Franco, Seth Rogen, and Jason Segal. As well as expanding the legendary standing of Judd Apatow in the patheons of Hollywood. But the heart of the show was Cardellini. The role of Lindsay weir allowed her to demonstrate her likability. Lindsay was a girl without a set clique. She never fit into a set category, she was too smart and driven to be one of the freaks, but too adventurous and rebellious to be a geek. Cardellini made us care deeply about the character as she navigated the dangerous waters of high school. Just look at how badass she is in the opening scene of the series.
While she mainly played the straight woman reacting to everything around her the show also did well to utilize her fantastic comedic sense as well.
After Freaks and Geeks Cardellini's career stalled a bit when she chose to join the sinking ship that was ER. She got lost in the large ensemble and it did not highlight any of her strengths. However, the shittiness of ER did not detract from her hotness and awesomeness.
Let's skip passed the unfortunate fact that she played Velma on the live action Scooby-Doo and hit the next career highlight, Grandma's Boy. She shocked me by being just as hot, if not hotter as a blonde. And in an underrated raunchy comedy, stole the show.
She went a little quiet after Grandma's Boy, but has been back the last couple years with a sexy turn as Don Draper's latest mistress and now as Jess' sister on New Girl. If there is a God, then this recent hot streak will result in her getting the lead of her own series within the next year. Lord knows she deserves. I'm not completely sure why Judd Apatow has never used her in any of the films he's produced over the last decade, but it would be great if he could redeem himself by producing a star vehicle for Cardellini. Make things right, Judd. I think you've cast your wife enough times to get you laid for the rest of your life.


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Vilnius welcomes a Polish team to mount a new production of Carmen
Autor: Julija Kalpokiene
When the Opera and Ballet Theatre last year put on its production of Red Giselle by Boris Eifman, it seemed that some time would have to pass before audiences would again be amazed by such an extraordinary premiere.
However, it did not take so long. A group of Polish artists who staged Bizet's Carmen in Vilnius once again proved that opera can delight not only through well-performed music but also through dynamic action and breathtaking images.
Premiere of the Year
The opera theatre had already staged Carmen, one of the world's most popular operas, eight times. Liutauras Balciunas, artistic director and chief conductor, was inspired for the ninth production by the version put on by Lech Majewski at the Polish National Opera in Warsaw a few years ago.
"I was fascinated: the stage was permanently bustling with activity and motion," he says. "It was a masterly combination of music and images."
He invited to Vilnius the same group of four Polish artists who have worked together for many years, three of whom have lived and worked in the USA now for the last 20 years.
This Carmen differs in many ways from the Warsaw production. One of these is the set, which to transport from one of Europe's largest opera stages to the small one in Vilnius would not have been possible technically. However, the producers themselves were pleased with the chance to create a more metaphysical and mysterious set and atmosphere for the play.
The production is unusual in that it has been mounted practically without any cuts, keeping to Bizet's score with particular fidelity.
"Most of the opera is supposed to be performed piano, although usually nearly all the quiet pieces are sung loudly," Balciunas says. "Technically, it requires immense skill from the singers."
It is a good opportunity for the company to show its full range of abilities. Sung in French (productions in French are very rare in Vilnius), nearly all the key parts are played by members of the company.
"I don't like clearly expressed meanings. A performance for me must contain some mystery," says Majewski, who allowed each of the three soloists playing Carmen to explore the character in their own way.
"I did not want to stick a label on the role, and say what Carmen should be like. It had to come about of its own accord. Every person is different, combining light and dark colours.
"Creation is a mysterious process, without any predetermination. It should look as if a show has been plucked out of the darkness and put on the stage."
Between Spectacle and Music
It would be difficult to say whether Majewski is more of a poet or a painter, a writer or producer, director or composer, as he has been successful in expressing himself in all these genres. Having begun as a scriptwriter and director of feature films in the late 1970s, he has also published three collections of verse and written stories.
The film Flight of the Spruce Goose, based on one of his stories, became his debut in America in 1985. In cooperation with David Lynch's studio, in 1990, he produced the film The Gospel According to Harry, to his own screenplay, in Hollywood; and later Basquiat, in New York, featuring Gary Oldman, Dennis Hopper, and David Bowie as Andy Warhol. In 1999, his film Wojaczek beat all his previous records at festivals, and won 20 prizes.
Throughout his career, Majewski, never abandoning film and the theatre, has kept returning to music, as well. His production of Penderecki's Ubu Rex, staged at the Lodz Theatre in 1993, drew him into the world of opera. The postmodernist opera The Black Rider, written by Bob Wilson, Tom Waits and William Burroughs, which he put on in Germany a year later, was recognised by German critics as the best-directed work in 1994/1995; while the Polish National Opera started its 1995 season with his Carmen. The French magazine Opera International chose that as one of the most significant events in opera in the world.
"Usually operas are valued for the music, but are not so strong on the visual side," Majewski says. "But opera is the only form of art where there is still some space left for creativity in these commercialised times. I think that those who write and produce operas work the hardest of all artists."
He is entitled to make this claim, because in 1996 he tried his hand as a composer too. His autobiographical opera, The Roe's Room, based on poems written in his youth, in addition to all its other awards, was recognised by the International Theatre Institute as one of the 12 best modern operas composed between 1995 and 1998, out of 500 possible works.


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4th Botched Abortion in 5 Weeks
Tuesday, January 22, 2013 marks the 40th anniversary of Roe v. Wade
But is it really "safe and legal" as the abortionists claim?
While abortion is always dangerous for the child targeted by abortionists, a recent disturbing trend at Planned Barrenhood in St. Louis is just one of many indicators that calls into question just how "safe" it is for mothers.
Saturday, January 20th (shortly after hundreds of of area Catholics commemorating the 40th anniversary of Roe v Wade left the mill), marked the fourth time since Thanksgiving that a mother left the mill in an ambulance. Did Planned Barrenhood wait for the pro-lifers to leave before calling the ambulance in hopes of covering up the incident?
Since Thanksgiving, we have also observed
a new abortionist
at Planned Barrenhood. Is there a connection? Is this "on the job training" abortionist style?
Will Planned Barrenhood warn mothers of this abortionist's history?
Will the St. Louis media seek the necessary answers?
Do not mothers coming to Planned Barrenhood deserve such due diligence on the part of
area media?
In almost 40 years at Planned Barrenhood we have witnessed plenty of mothers leaving in ambulances, but this rate is unprecedented.
Abortionists continue to claim abortion is "safe and legal". While abortion has always been dangerous for the child targeted by the abortionist, this disturbing trend calls into question this claim for mothers as well.
Defenders of the Unborn has notified the St. Louis Board of Healing Arts about this trend but the board has decided to take no action at this time.
Defenders of the Unborn has requested the911 tapes (required under the Sunshine Law) but the city has refused, continuing to cover up for the abortionists.
The pictures below are from January 20th at Planned Barrenhood in St. Louis.
Only Planned Barrenhood can answer these questions. Will they be asked? Will mother's be protected?
Defenders was successful in protect at leas
2 mothers from this fate as theywent
instead across the street to the Thrive mobile Pregnancy Resource van.
For more information, please contact:
Mary Maschmeier
Defenders of the Unborn
Alternate contact: John Ryan


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Posted by Jack Ferguson
With the coming elections in November, and politicians running back and forth everywhere screaming like their shirts caught on fire, I am reading a lot about the apathetic (or at least 'unenthusiastic') youths. Are we so apathetic? If so, how did we get here?
On a recent train ride up from New York City, I met and befriended a man who had grown up in our parents' generation. As we talked, I realized something about the modern day discussion on youth culture: comparisons of our society to that of the Sixties are everywhere. With nearly every mention of the Iraq War comes a correlation to the Vietnam War; the threat of global warming looms as large as the Cold War's specter of Mutual assured destruction; universities have an even stronger toehold on the liberal discussion than before.
It is not unreasonable, then, that my new friend asked me: why aren't all you more politically active? Why don't you take to the streets?
By a better comparison of the Sixties to the present day, I hope to draw better distinctions. Hopefully this will leave us better able to define exactly what we are. Drawing analogies to the overarching dilemmas (lies that got us into a massive war; potential planetary ruin) have some merit, perhaps, but the comparison between generations is erroneous.
MTV, video games and Facebook are not the causes of our hesitance and lack of action nearly as much as the historic moment in which we were born.
Our parents, of the picketing, protesting and pamphleteering generation, were born of the Baby Boomer generation, into a world of both U.S. prosperity and deep uncertainty. I think it is safe to say that by the time of the Gulf of Tonkin Incident in 1964 (after which Congress wrote President Johnson a blank check for the Vietnam effort) our parents were approximately the age that we are now. They lived in a divided U.S., wherein the Civil Rights movement was struggling to have its voice heard. Political activism and politically charged discussion pervaded their generation both abroad and at home. Moreover, the undercurrent of this generation was the threat of the Cold War, which started as soon as WWII ended – that is to say, started with our parents' birth.
They were born at the onset of the Cold War, and into a divided nation that did not know what to do with its prosperity, responsibility and rocky history. The nation's divisions were heightened all the more so with the draft and the economic and racial inequalities of the U.S. army.
Contrast this with when we were born – the median of which I will put at 1990. We were born into the pinnacle of U.S. prosperity and security. Our major, national moral confrontation (in the media, at least) was whether or not the president was the recipient in an instance of oral sex. When our parents saw the dogs and water hoses used in Montgomery, Alabama, they saw reflections of a system, perpetual and pernicious, eating away at the Bill of Rights. Our two political worlds defy comparison.
We – the children of the Internet boom and Walmart – were hurled into a world without precedent. The End-Game horrors of global warming present themselves in a thousand different man-made processes, not from a big red button at a distant missile silo. The terrorist attacks of Sept. 11, 2001, were from without, and therefore much harder to grasp and rail against.
What does a 'War on Terror' even mean? This war has no centralized enemy to confront, rather a proliferated ideology. Too: this ideology is abhorrent beyond debate; this was not so in the Sixties, with Communism.
So how do we become politically active? How do we go from a world of one huge enemy with one huge weapon to that of myriad possibilities and processes that potentially leave us vulnerable, or even threaten to destroy us? How do we open a debate on what political activism means when we cannot decide on what to confront first?
I suspect that this atmosphere contributes in a major way to the Tea Party and similar movements (which exist among environmentalists and liberals, too) that are so radical as to see the world in binary terms.
Surrounded by variables, we entrench into simplicity. Which is understandable. But we, the Young and Educated (like it or not), who are beginning to perceive nuance and contradiction, who balance variables and evaluate confusion, are hamstrung.
We search for something intelligible (that is also intelligent) and what do we find? Where do we go with our world of many threats, unschooled and under-nurtured from birth in the ways of political action? We need to form an active political consciousness and thrust.
I'm not about to propose that I know how to do that; I wish I did.You can start by voting.
Jack Ferguson is senior history and English double major from Philadelphia, Penn.


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Hey there, I'm PJ King, a technology investor involved in start-ups.
My current interests are focused on blockchain & cryptocurrencies, though I invest in many other things too.
You can follow me on Twitter , find me on LinkedIn, or contact me right here.
Some current and former projects are outlined below.


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Gaelynn Lea has been actively performing since 2006, both solo and with a number of musical projects in Minnesota. Currently Gaelynn is on tour performing solo sets of her haunting original songs sprinkled with experimental fiddle tunes; her aim is to create a meditative, layered sound that allows the listener's mind to drift.
Her most active collaboration is The Murder of Crows, an atmospheric alternative duo with Alan Sparhawk of LOW. Together they recorded an EP titled "Imperfecta" in 2012. Their original song "When We Were Young" was featured on the Sundance Channel's acclaimed drama "Rectify" in June 2014.


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Posted September 9, 2015 by
Tags: Urban Development Urban Leadership Studio
[Hunter Hambrick ('17) is a 2015 CUE Urban Leadership Fellow. His Urban Leadership Studio consists of an early summer experience with S.O.S. (Service over Self) in Memphis, staffing the Urban Track of Wheaton Passage, and leading his peers in a vocational discernment group during his fall semester in Wheaton in Chicago. This post is an adaptation of Hunter's original post,"Developments: Things I've Learned" published on Hunter's blog.]
I thought roof repair simply required replacing old shingles with new ones. But a dilapidated roof (certainly a troubling matter in and of itself) is usually a more superficial sign of the home's deeper structural flaws. Often underneath shoddy patch jobs lie faulty wiring, rotten drywall, blocked sewage and foundational imbalances. In this way, home repair serves as a microcosm for the larger world of community development.
As in a home, superficial needs never stand alone. Many onlookers like myself (community outsiders) regard the plight of inner city residents (community insiders) and remark, "__________ is the problem with the home!" That is, if a new roof is the solution to a leaky house, then education or employment must be the trick for a broken city. But inherently interconnected phenomena like roofing and revitalization cannot be reduced to one or two "core issues." Both are more multifaceted than that.
During Early August, a Wheaton professor and I helped guide six freshmen males into their time at college. I led the urban portion of Wheaton Passage, an orientation experience designed for incoming students with a focus upon community, service & justice, the life of the mind, and spiritual formation. The last component of Passage, "spiritual formation," inadvertently bombarded my thinking throughout the entire process. It seems to me that the previous elements of the program all serve the final concept.
I underwent Passage my freshmen year as well and though the actual experience ended long ago, the formation of my spirit has not. Wheaton Passage is an optional program for Wheaton students, but the ongoing "passage" of the spirit is not. I am always being formed. The only question is, "By what?" These bright eyed and bushy tailed young men eagerly explored and experienced community, service, justice, and the life of the mind. I, their leader, hope to follow their lead over the months and years to come.
Wednesday, August 26th marks the beginning of my time in the great city of Chicago. As a part of Wheaton in Chicago, I will intern at Chicago Neighborhood Initiatives, a neighborhood-based community development organization in the Pullman Park District of Chicago's Southside. CNI works holistically to not only meet an impoverished neighborhood's perceived needs, but also augment its inherent strengths. In other words, CNI works through the ABCDs of urban revitalization through Asset-Based Community Development.
Removing the shingles of a roof at SOS revealed moldy ceilings and faulty wiring, but it also led to the discovery of ornately designed glass work and nearly century-old oak rafters. Who knows what types of "assets" might lie beneath even the toughest features of Chicago's most impoverished neighborhoods? And who knows how this "passage" of my own life might form me in deeper ways than I could possibly envision now?


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Wookey Hole is to relaunch its handmade paper grades, as the mill looks to expand into the commercial market sector.
The mill at Wells in Somerset, once owned by paper producer Inveresk, has a papermaking history that dates back to 1610.
At the height of its paper production, it was the largest rag-made paper mill in Europe, producing 35,000 sheets every week.
Wookey Hole general manager Daniel Medley said the mill had a unique history, and was probably one of the few still making handmade paper in the UK.
The Victorian paper mill produces a range of handmade papers available for commercial sale, including products made from cotton, hemp and denim, along with art papers and stationery grades. All of which will be renamed to reflect the local area.
To coincide with the relaunch a website detailing the mill's history and products has also been developed.
Former circus impresario Gerry Cottle acquired the paper mill and Wookey Hole caves in January 2004.
Madame Tussauds bought the caves and attractions in 1973, before selling out to a management buy-out team in 1989, from whom Cottle purchased the attraction.
The site had been on the market for 15 months, with an asking price of 6.5m.


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The Cancer Experience Survey
Health and Social Care Trusts have begun posting out Northern Ireland's first cancer patient experience survey.
Around 5,500 adults, who were diagnosed with cancer and discharged from hospital between 1st December 2013 and 31st May 2014, will be asked to take part and report back on their experience.
Macmillan has been campaigning for surveys to be carried out right across the UK and has jointly funded the initiative with the Public Health Agency. The data will show if cancer care targets are being met and where improvements can be made.
Heather Monteverde, General Manager for Macmillan in Northern Ireland, says:
'It's vitally important to measure survival rates and waiting time targets, but it's equally important to find out what patients really think about the quality of care they receive in and out of hospital. Cancer treatment goes beyond surgery, radiotherapy and chemotherapy, we need people-centred care, not just symptom-focused treatment.'
The Cancer Experience Survey will be sent through the post, with a Freepost envelope to return the completed form. There will also be a FREEPHONE helpline, so anyone who needs assistance with the survey can call 0800 783 1775.
If you have any questions about Macmillan we would love to hear from you .
You can also follow us on Facebook, Twitter, Flickr or YouTube.
© Macmillan Cancer Support 2019
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Computational Powerhouse Hidden in Island Jungle
Seemingly unglamorous RF atmospheric research requires surprisingly complex calculations performed by the equivalent of supercomputing systems.
Perhaps one of the more unusual applications of serious computing power is innocuously located within the sweltering jungles of Puerto Rico. Inside a modern, air conditioned data center in the Aeronomy Department of the Arecibo RF Telescope Observatory, scientists and engineers study the upper regions of the Earth's atmosphere. Their goal is to help improve the reliability of radio and satellite communications for the military, security, and global telecommunications industries.
Achieving this goal requires compute-intensive systems to handle the complex algorithms and exponential manipulations associated with high-resolution RF signal analysis. What follows is a brief history of the decade long challenge to implement the most appropriate computing technology, from early computers to today's multicore parallel architectures.
Resolution Matters
Using atmospheric radar, engineers transmit a coded RF signal into various layers of the atmosphere. They then compare it to the received signal. In the past, a digitally modulated Barker Code was used to compress the pulse width of the bursted transmitted signals, notes Arun Venkataraman, head of the Arecibo Observatory Computer Department. Compressed pulsed signals achieve wider pulses and better signal-to-noise ratios than un-pulsed signals—a necessity for high-distance resolution. The Barker pulse employs binaryphase- shift-keying (BPSK) modulation, which is why it's also used in many spread-spectrum applications like the 1- and 2- Mbit/s IEEE 802.11x wireless-communications standards.
Continuing refinement in both RF performance and electronic technology have resulted in the adoption of higher-resolution—hence longer code length—signals like the coded-long-pulse (CLP) sequence. This pulse sequence is so long that it must be decoded in sections. This requires a compute-intensive decoding process that involves the calculation of numerous autocorrelation functions. The resulting data is used to determine the intensity or concentrations of the reflective atmospheric layers all the way up to the most upper regions (i.e., the ionosphere). All of this information is critical to understanding how radar signals interact within the different layers of the atmosphere.
Achieving the computing performance necessary to decode and analyze the CLP signals requires the use of two sets of Intel® Xeon® processors 5500 (16 cores each or 32 cores total).
How were these compute-intensive calculations handled before the advent of modern multicore processing systems? What options—ranging from array processors to field-programmable gate arrays (FPGAs) and graphics processing units (GPUs)—are being explored for the even-greater computational needs of the future?
Past Computational Technology
In the 1970s, some of the earliest atmospheric radar work at Arecibo used array processors from a company called Floating Point Systems (Portland, OR). Array processors are specially designed to process arrays (i.e., matrices of numbers). Several of the floating-point-system (FPS) array processors were connected to a 24-bit Unisys Aries minicomputer. One of the FPS processors was used for control while the other functioned as a co-processor to calculate Fast Fourier Transform (FFT) sequences.
As computational needs increased, the FPS and minicomputer were replaced in the 1990s by a SkyBolt system. It included Intel's 8000 and 9000 series processors. According to Venkataraman, multiple SkyBolt systems were needed to achieve the necessary processing power. Because it proved extremely difficult to synchronize all of these systems together, the effort was abandoned. Interestingly, interconnect issues remain a challenge for today's parallel-processing multicore processors.
For a while, the engineers at Arecibo struggled with general- purpose machines. They actually built platforms based on Motorola's G-5 processors—a 64-bit PowerPC architecture that was the successor to Motorola's PowerPC 7400 series. The engineers even created a cluster of Apple G5 processors connected with Sun's Grid tools to create a parallel processing environment. But even these successes weren't enough to meet the growing computational needs. Finally, the Intel Xeon processor-based platforms were used to achieve the current compute power. But will these workhorses be sufficient for the future?
Figure: Computing servers with the Intel® Xeon® processor 5500, the first processor with the company's Nehalm architecture. Also shown – on the right - are a bank of Aberdeen network disk servers.
Future Computations
To meet the ever-increasing need for greater computing power, the computer department at Arecibo considered buying a Cray supercomputer. But careful analysis by Venkataraman suggested that the same processing performance could be had for less money by complementing the existing array-processor architecture with several graphics processing units. As a result, computer engineers are currently evaluating nVidia's 512-core Tesla series of high-end-performance GPUs. Their goal is to use the inherent parallel architecture of the graphics chips to facilitate greater levels of processing speed and performance. Both the Tesla and the soon-to-be-released nVidia Fermi—with thousands of cores in a board—are being considered.
Using GPUs is nothing new at Arecibo. In addition to the Aeronomy department, Astronomy is another field where intensive data calculations are needed. According to the observatory's website, "In 1993, the first pulsar in a binary system was discovered, leading to the important confirmation of Einstein's theory of general relativity and a Nobel Prize in 1993 for astronomers Russell Hulse and Joseph Taylor" (http://www.naic.edu/accomplish.php).
Shortly after that time, according to Venkataraman, Taylor bought a special-purpose vector array processor called the Super Harvard Architecture Single-Chip Computer (SHARC)—a high-performance digital signal processor (DSP) from Analog Devices. This type of machine was needed to handle coherent dedispersion from the pulsars under study. Dispersion occurs due to the great distances between pulsars and radio receivers on the Earth. What starts out as a sharp, well-defined signal from a pulsar becomes a flattened smear of frequencies when it reaches the Earth. Coherent dedispersion is a technique that greatly improves the timing of pulsars. It requires numeric transformations that involve the multiplication of millions of complex exponential functions. This is an extremely processor-intensive set of calculations. The Arecibo Observatory works with the Green Bank Ultimate Pulsar Processing Instrument (GUPPI) at the National Radio Astronomy Observatory (NRAO) in West Virginia to perform these complex calculations.
John Blyler can be reached at:


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With a Monday deadline looming to prevent the departure of conductor Osmo Vanska, Minnesota Orchestra management today revealed details of its latest contract offer to locked out musicians.
The three-year deal would cut musicians salaries from an average of $135,000 a year under the old contract to $104,500. Each musician would also receive a $20,000 signing bonus, management said.
The new proposal, made possible using additional money in a bridge fund recently created by 15 local foundations and companies, would still result in a $3.6 million deficit over three years, orchestra officials said. Management wants a musicians vote on the offer by noon Monday.
Blois Olson, a representative of the locked out musicians of the Minnesota Orchestra say they are offended by the way management released its latest proposal.
Olson said the musicians are upset the offer was made in public and not through the mediator, former U.S. Sen. George Mitchell.
"Musicians are deeply offended that once again management has left the Mitchell process, violated the terms of the Mitchell process," Olson said. "The musicians are in conversations with the mediator and will continue to work through the mediator."
Olson said the musicians will only react to the proposal through the mediator.
Orchestra President Michael Henson said the orchestra's board and management wanted the public to know about the offer because it included money from local foundations and companies.
"We felt that it was important that as this offer was generated by the community that we actually make the community aware of this offer outside the mediation process," Henson said.
Vanska has said he needs to be rehearsing with musicians by next week to get ready for Carnegie Hall concerts in November and will resign if they are cancelled.


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In the last three, four days I've been creating 18 boxes. Eighteen friggin boxes. I *think* I am done – I am undecided whether to create two more, or to just quit now. We'll see. Need a break anyways, and I'm in no hurry with the two latter. I think. I know I should streamline this process, create duplicates and stuff, but I hate creating exact dupes – I need to create knowing I don't have to do exactly the same thing as I did. Sure, some might look the same, but it's not intentional – I just took what I had and created what I found satisfactory. Today I'll share the ones created with Pink Paislee and Crate Paper.
I was undecided on whether to share them here or not, and whether to add names or not to the fronts. I mean – I love creating and I love sharing, and I hate waiting to be able to share. And some of the recipients' reading this blog (if you do and see your name here, pretend you're surprised when you get this gift mkay?) So I changed my mind a few times on the names – but in the end, most are with names, but some are just generic.
The images are so-so – I mean – who has the patience to snap 18 friggin boxes in a row and make sure all the image's swell? Not me.
I truly love the Father Christmas-collection from Pink Paislee. And you can see the interview with the designer of this collection here. And if you weren't aware: there's a giveaway collaboration between Pink Paislee and Petaloo going on right now. Hop over to enter!
See the diagonal here? Had some scrap-papers which were like this – so figured I'd just utilize it that way
This one's created with Crate Paper's Snow Day collection. I joined Lucy Edsons color-challenge on the Crate blog. Do join too!
And a simple one with papers from 3ndypapir and letters from Prima (love these letters).
Btw, here's some of the boxes undecorated, taken with my iPhone. LOTS OF WORK I TELL YA! But it feels good getting rid of the non-used-cardstocks I've hoarded "just-in-case-I'll-ever-need-this-or-that-color"
Right. Even though I'm done with the boxes I still have lots to-do-scrap-projects. Ciao for now!
Ps. Thanks for the well wishes re my exam. I have my fingers crossed too!
Oh and a question I got:
Vicki Said,
Hey Ania! Thanks for putting up with me as your roomie!!! It was great getting to know you!
I love your PHOTOS!!! What lense did you use and which Nikon do you shoot with?
Thanks! I'm using a D700 body and a v24-70 f/2.8 lens, although ever since I got my iPhone I've used it more and more for the snapshotish pictures. Most of the square non-scrapbook-images (and with fancy frames etc) you've seen here lately are actually iPhone-images (taken with either the Hipstamatic or the Instagram-app). It's a whole new way for me to shoot, and I love it!


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The lighting inside Mayfair's well-heeled "Whiskey Mist" bar was frankly appalling. Unable to use flash, I ended up relying on two lights erected either side of the small stage by the videographer (who at the last moment was barred from actually recording the event!) Nonetheless, I still had to push my camera farther than I was really comfortable with, dialling up the sensor's sensitivity to dangerously noisy levels.
Maintaining focus was a huge problem. My Canon 5DMkI's autofocus simply couldn't cut it, certainly not with a wildly animated performer in such dim conditions. I was also shooting wide open with a wafer thin depth of field. Centimetres, literally. In the fraction of a second between me locking focus and squeezing the shutter button, Johnny more often than not had slipped out of focus.
Although I bristle at the suggestion of using technology to fix a problem which may in fact be one of technique, it was quite clear that having a more sensitive autofocus and a selection of f1.2 primes would have helped enormously. A hotshoe-mounted AF-assist light would have come in mighty handy too.


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I Love My BodyFebruary 11, 2017
I love my body. I haven't always been able to say that and I can't always say it now with confidence, but I do love it.
I love my hair even though it gets tangled just sitting there — it's my favorite of my physical traits.
I love my muffin top, even though it forces me to dress accordingly — it gives me more room to eat French fries.
I love the stretch marks on my thighs that I must've gotten when I was like 12 — they're my tiger stripes and make me feel strong and powerful.
I love my eyes, even if one is squintier than the other — they help me spot puppers across the street that I can run to and pet.
I have a horrible singing voice — but because I know I'm no good, I have a lot of fun doing karaoke.
I like my legs — even though they're disproportionately long to the rest of my body, they make me look like I'm in shape (which I'm not).
I like my acne — it keeps me humble. My skin's not perfect and I'm not perfect. But I'm still pretty darn great.
I don't feel grateful every day, but my body has gotten me through it all. It helps me cry when I need to feel better, it helps me carry cat litter up three flights of stairs more often than I'd like, and it helps me hug the people (and cats) that I love. I'm not ashamed of this picture and I wasn't ashamed to go to the beach today, even though I wasn't ready for swimsuit season when I booked a flight to Florida a week ago (but let's be real, I'm never ready for swimsuit season). I'm not saying I can't improve — because I stopped running after a third of a mile at the gym with the excuse of typing this AKA I was too tired and out of shape — but I love where I'm at and am excited to grow.


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Islamic Interpretation of Dreams (Ibn-i Sirin):
In a dream, exclamation of Godâs sovereignty, i.e., uttering the formula âLa Hawla Wa La Quwwata Ilia Billahâ (There is no will or power except that of Godâs Almighty) means constant repentance in wakefulness and hope for salvation.
It also means conquering oneâs enemies.
(Also see Exalting Godâs oneness)


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After living in Los Angeles, the entertainment capital of the world, for nearly a decade now, I've seen friends, coworkers, and acquaintances roll their eyes or let out a collective "Sheesh!" every time the front page of Variety announces in bold letters the news of a flashy new project headed by some bigwig looking to fatten up his bank account. And after living here for ten years, I've seen those friends, coworkers, and acquaintances give up on Tinseltown.
I can understand why some have quit "the biz." It's not because they're weak or incapabale of keeping up with the Kardashians. Some do have valid reasons or extenuating circumstances keeping them from keepin' on. But sometimes it's because most of them are genuinely fed up with the constant barrage of detrimental doodoo this business tends to spew out. And while I don't see myself packing up and hightailing it back to where I came from (New Rochelle, NY, FYI) anytime soon, I'd like to see if I can speak for those who have washed their hands clean of anything that has to do with the Business of Show...
Hollywood -- and I use this term very generally to cover all grounds of entertainment -- you have become a hot mess.
You have managed to convince millions of people that remaking a shit show from yesteryear, raping childhood memories, adapting flashy comic books, and ressurrecting old ideas warrants every American to hand over $12 at the box office. You've convinced another several million people that watching the undeservedly rich and famous whine about their love lives via vapid confessionals makes for compelling television. You've told children across the country that they deserve a record deal and a fat bonus check after prancing around on stage in front of judges who get paid seven figures to shout out catchphrases. You've conditioned youth to respect wealth and privilege and accept that hard work isn't necessary. You've basically created a sub-industry that indulges narcissistic tendencies and feeds off insecurities (reality TV). You've taken international properties and reformatted them for English-speaking audiences because, frankly, you think middle America doesn't like to read subtitles. You continue to write checks to (and inflate the ego of) this man. You continue to let Adam Sandler make movies. You've turned "films" into "franchises" for the capitalist sake of raking in more cash and compromising creativity and originality in the process. You've inspired many to adopt the philosophy of "You scratch my back, I'll scratch yours" for the wrong reasons, prompting others to become paranoid and cynical about the true intentions of acquaintances. You hand out awards to actors because their publicists tell you to do so. You thought The Adventures of Pluto Nash was a good idea. You gave Snooki and book deal. You still consider women a minority or a "tough sell," even though you'll never admit it, especially when something like a Bridesmaids comes along.
As you can see, it's easy to rip on an industry that has so much power and influence in the world and permeates every aspect of civilization. But after working and living here in Ground Zero, I will attempt to look on the proverbial bright side, to see through the bullshit, and to maintain some positivity.
Why am I not ready to quit on Hollywood? Because I still believe there is a decent minority in this factory town that believes in what they do. I won't let the abundance of bullshittery of the business deter me from doing what I am passionate about. I simply won't the let the bad outweigh the good. I have met and befriended countless others who are similarly (and genuinely) passionate about their work and continue to act as my support system. I appreciate the constant inspiration that hits me every week as I continue to learn, grow, and accomplish. I'm blown away by the collaborative spirit and camaraderie that's formed when working on a project. I enjoy some of the perks that come with having friends in unions (Free movies! Award shows!). I get a high whenever I walk out of theater after seeing a kickass film receive a round of applause from its audience. I love that I can wear flip-flops in January. I take comfort in knowing I'm surrounded by thousands of others who feel the same way. And it's that comfort that prevents me from sinking into that abyss of negativity and propels me forward, inspiring me to keep on keepin' on.
If that makes me a naive optimist, then take a good look at yourself and figure out why you're so quick to snarl before you poo on my parade.
Sure, there'll be days when I'll tsk-tsk at the news of a 3D remake of a film I saw fifteen
And with that, I leave you with a little musical treat from the talented Mr. Robbie Williams that once worked as my theme song back when I arrived in Tinseltown in the summer of 2002:
I should remember to play it more often.


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CET Arts
CET Arts brings the world stage to Greater Cincinnati and showcases the arts in our community.
When you watch CET Arts, you'll have a front row seat for the best in drama, visual arts, dance and music, ranging from symphonic to bluegrass. You'll enjoy arts programs and performance specials featuring Greater Cincinnati arts organizations along with encore presentations of PBS favorites, such as Great Performances at the Met, Masterpiece, Soundstage and more.
In addition to being available to over-the-air viewers on digital channel 48.3, CET Arts is available to Spectrum digital tier customers (Cincinnati channel 987 and Northern Kentucky channel 192), and Cincinnati Bell Fioptics Basic and Plus subscribers (channels 4 or 248). (See channel listings here.)
Local programming on the CET Arts channel is made possible by the following generous supporters:
The Louise Dieterle Nippert Musical Arts Fund
The William S. Rowe Foundation


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Get In Touch
1895 N. Ventura Ave.
Ventura, California 93001
Phone: 805-653-1943
Download Our Catalog


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Prospective Families
Dear Prospective Families,
Thank you for your interest in Our Lady of Mount Carmel School. We are so happy that you are considering our school for the educational and social needs of your child(ren). We are a Catholic Elementary School, grades Pre-Kindergarten 3 through 8th grade, located near I-691, MidState Medical Center, and the Meriden Mall.
You are encouraged to visit OLMC and tour the campus, meet with Christa Chodkowski, Principal of OLMC, and ask questions before sending in an application for admission.
Appointments to visit or shadow can be made by contacting the school office at;
(203) 235-2959 or via email at firstname.lastname@example.com
We will be in touch shortly after receiving your email or leaving a message.
We look forward to meeting you and your family!


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About Us
Before & After
2018 Projects
Client Testimonials
"Best Landscaper & Lighting in SJ!"
"Mark designed and executed our backyard landscaping from start to finish. It is everything we imagined and more! We have received so many compliments. Job was perfect down to every little detail. The lighting made it magnificent to admire long after the sun sets."
"Beautiful Work"
"Mark and his guys from start to finish do a wonderful job. My family and I recently had a front step and walkay done. The whole time it was being done Mark and his guys made sure the project went smooth. It turned out beautiful and we have received alot of compliments. I would highly recommend Sherwood, I know they will be doing alot more work at my house."
"Professional, friendly, quick & great quality!"
"I would highly recommend Sherwood Landscape and Design. They are very professional, friendly, quick in their work and show great quality and creativity. They can think through different scenarios and come up with great designs. Highly recommended!"
"Quality work, great bunch of guys! Highly Recommend their service. "
"Mark and his team did a great job of design and execution of our project. Leave it to a professional to think of things you don't know are possibe. Quick work is exactly what I eexpected. We will be doing the next project together. Thanks guys!"
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The service that I recieved from Sherwood Landscaping was a great experience. From the first visit to scope the job to the finishing touches, everything was done in a first rate fashion."
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U.S., Russia Sign Pact On Nuclear Cooperation
Wednesday, May 7, 2008
MOSCOW, May 6 -- The United States and Russia signed a long-sought agreement Tuesday on civilian nuclear cooperation, which officials said would offer Russia lucrative new business while limiting the risk of material being used for weapons.
President Bush had announced his intent to pursue such a deal almost two years ago, but it was delayed by debate within the administration and in Congress over Moscow's policies, particularly toward Iran.
The framework agreement could open the way for Russia to import, store and reprocess thousands of tons of spent nuclear fuel that had been supplied by the United States for reactors around the world, a business potentially worth billions of dollars.
The agreement would also reduce the risk of countries developing their own nuclear fuel facilities that could divert material into weapons programs, according to U.S. officials. And it would facilitate joint ventures between the U.S. and Russian nuclear industries, the officials said.
"The U.S. and Russia were once nuclear rivals," said U.S. Ambassador William J. Burns, who signed the pact in Moscow with Sergei Kiriyenko, the head of Russia's state-owned nuclear company, Rosatom. "Today, we are nuclear partners with unique capabilities and unique responsibilities for global nuclear leadership."
Kiriyenko said the deal would help "to eliminate the legacy of the Cold War."
But the agreement is likely to draw opposition in both and the United States and Russia. It does not require congressional approval but could be blocked by majority votes in the House and Senate.
"It would be a mistake for the United States to provide Russia an important civilian nuclear benefit while Moscow itself continues to assist Iran's nuclear and missile programs," Rep. Edward J. Markey (D-Mass.), a member of the House Energy and Commerce Committee, wrote in a May 1 letter to Bush.
Environmentalists in Russia have expressed concern about the country's ability to transport and safeguard spent nuclear fuel. Russia passed a law in 2001 allowing the reprocessing of nuclear fuel from other counties.
"There were very sharp debates about this at the start of the decade, and there are both environmental questions and concerns about Russia's capacity," said Alexander Pikayev, a disarmament specialist at the Institute of World Economy and International Relations in Moscow.
Opinion polls show that most Russians oppose the government's plans. But the ability of grass-roots organizations to protest is limited in a country where the Kremlin tolerates little dissent.
The deal must be ratified by Russia's lower house of parliament, but that chamber is dominated by the United Russia party, which generally rubber-stamps Kremlin decisions.
Russia is planning to build a nuclear fuel reprocessing facility in eastern Siberia. An agreement with Washington is key to the plant's viability, as the United States controls the vast majority of the world's spent fuel through agreements with third countries that it supplies with nuclear material.
The agreement signed Tuesday, the last full day of Vladimir Putin's presidency, is a rare instance of open cooperation in a relationship that has frayed over a host of issues, from the expansion of the NATO military alliance to Russia's stance on Iran's nuclear ambitions.
"A lot of this was done out of a sense of legacy and obligation because nothing in it needs to be done now or done at all," said Henry D. Sokolski, executive director of the Nonproliferation Policy Education Center in Washington. "On Iran, Russia's support has not been zero, but to say Moscow has been very helpful is a stretch. You have to argue that there has been a very stiff turnaround" inside the Bush administration.
An agreement was initialed just before a Bush-Putin summit last summer, but some officials in Washington appeared to balk, suspicious about Russia's continuing cooperation with Iran. Russia is helping Iran build a nuclear power plant and is a major arms supplier.
International attention has focused on Iran's controversial program to produce enriched uranium, which can be used either as reactor fuel or in making weapons.
"Two years ago, no one would have believed that Russia would support three consecutive U.N. Security Council resolutions against Iran," Pikayev said. "It appears to have helped to turn the debates inside the American administration in favor of this agreement."


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01. Livin' insanity by Moby
02. Summer guitar by C-Jeff and Manwe
03. Little sweet guitar song by Drolix
04. Funkastar by Med
05. Stress the guitar (short) by ???
06. Barcelona by Soulbrigade
07. Guitar symphony by Cairbre
08. Bloody eye rock'n'roll by ForceQ
09. Electric beards and fake guitars by KiWi and Timo
10. Grease release by Sly Spy
File 1: hardread podcast 19.cue
File 2: hardread podcast 19.mp3
Size: 30.255.2326bytes (~29MB)
Lenght: 31:30min.


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Okeechobee County Florida Board of County CommissionersHome Menu
Albie Scoggins, Community Services Director
1718 NW 9th Avenue
Okeechobee, Florida 34972
Office: (863) 763-6950
Fax: (863) 763-0662
email: firstname.lastname@example.com
Tiffany Gould - Project Coordinator
Jenna Stephens - Receptionist/ Front Desk Clerk
Terra Scurry - Program Specialist
Mission Statement
The basic function of the Parks & Recreation System is to provide daily, year round recreational opportunities to all citizens of the community. It entails utilizing both indoor and outdoor areas, spaces and facilities for programmed and spontaneous activities.
Parks & Recreation... "The Benefits Are Endless"
- Visit our new Facebook page at www.facebook.com/okeeparksandrec
Okeechobee County Sports Complex -
580 NW 27th Lane - Okeechobee, FL 34972


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You are currently browsing the monthly archive for March 2009.
Most young earth creationists who have studied the issue will make a distinction between evolution within a species (micro-evolution) and evolution from species to species (macro-evolution). The former they liberally embrace; the latter they reject as unbiblical. The distinction is that in microevolution, the gene pool is diminished, whereas it is increased in macro-evolution.
Is evolution really limited to occurring within species only? What about within a genus? Or a family? At what point does a YEC draw a line in the sand and say, "This far you may evolve and no farther!"
In the Answers In Genesis article "Were Dinosaurs On Noah's Ark?", the author makes an interesting observation about micro-evolution as he explains how so many different species could fit on the ark:
Creationist researcher John Woodmorappe assumed, for his calculation, that each "kind" would be the ancestor of all "species" in a modern "genus" (plural genera), meaning that only about 8,000 animal genera (including some extinct animals), and when multiplying by two, meant that over 16,000 animals had to be aboard. When you realize that horses, zebras, and donkeys are probably descended from the horse-like "kind", it should be clear that Noah did not have to carry 2 sets of each such animal. Also, dogs, wolves, and coyotes are probably from a single canine "kind", so hundreds of different dogs were not needed.
According to this article, the line in the sand for a YEC is the genus. Evolution can take place as much as it wants but only within the confines of a genus. But what if we go back one classification, from genus to family? Can evolution take place within a family? If we take Woodmorappe's definition of "kind" strictly, then the answer is no. But let's consider this within the following example. Lions are in the Panthera Genus, but house cats are not. Both, however, are in the Felidae Family. I do not doubt that a YEC would have no problem lumping both cats and lions under one "kind." So should we include families, then? If we can include families, what's to stop us from going up an order, phylum, class, etc.?
If a YEC finds it acceptable that a horse "kind" can result in zebras, mules, and horses, why would it be unacceptable that a carnivorous "kind" should result in cat-like animals, dog-like animals, etc.? It all seems sticky to me. I would imagine that a YEC would say that the difference has to do with the gene pool increasing or diminishing. My knowledge of genetics is close to nil, so I really can't contradict or agree with that answer. Even if this explanation is accurate, why can't we say that a carnivor-like "kind" lost genetic material and became a lion in one instance and a wolf in another instance?
I think the issue goes back to Genesis 1:24, which says that God created animals according to their kinds.
And God said, "Let the land produce living creatures according to their kinds: livestock, creatures that move along the ground, and wild animals, each according to its kind." And it was so.
It seems to me that there is an awful lot of straining over where evolution may happen and where it may not, all for the sake of maintaining the "kinds" mentioned in the above verse. This seems so unnecessary to me. Does evolution in any way negate the fact that God made animals according to their kinds? Whether God uses evolution or fiat creation, the end result is the same: different kinds of animals. Verse 24 is still true.
So tell me, wordpress people (YECs and non-YECs alike). Am I missing the boat here? Is there a case to be made that it is one thing for a species to form within a kind and another thing for a species to form into a species that is markedly different? Is genetic information really lost going from the original horse kind to a zebra or a mule?


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Harris Schrank Fine Prints, New York, New York, USAWe maintain an inventory of a dozen or so Brockhurst prints.
Artnet homepage for this artist3 artworks in total
Annalie's Fine Art Gallery, Santa Cruz, CaliforniaUna The Fine Art Society, London, United KingdomDeux Landaises, circa 1920 Harris Schrank Fine Prints, New YorkL'Eventail (The Fan)
All images and text on this Gerald Leslie Brockhurst page are copyright 2010 by John Malyon/Artcyclopedia, unless otherwise noted. Note that the listings on this site are a unique compilation of information and are protected by copyright worldwide.


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I'm a fan of the BBC sketch show Horrible Histories, and I also have an interest in ancient Greek and Roman culture. So this book is something I would really like to read.
And it's very nice to read. Of course is it a children's book, but it is still nice and there are still some thing in it I didn't know. It focusses more on the weird / gore (but still OK for a seven-year-old) details of history. The passages are short, and there are a lot of comics drawn next to the text. I'm quite sure I would have loved to have these books around when I was a kid.


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Broadcast a Live Event – Adobe Flash Media Encoder
Begin by downloading the encoder:
1.) In your encoder, select both your Video and Audio device from the drop down boxes next to "Devices" and the select the Bit Rate that you would like to stream at.
2.) Next enter the Server URL and Stream name provided by your host.
3.) Click on "Connect" located below the Stream name in the encoder. The Connect button will change to say Disconnect and a Connected green bar icon will appear in the lower left hand corner.
4.) If you would like to create a backup copy of your live event, please select the "Save to File" option in the encoder and enter the name you would like for the file.
5.) Click on the Start button located at the bottom and your stream will begin broadcasting.


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The Bacon Brothers at Koerner Hall
For Immediate Release: August 10, 2010 • Please include in your listings/announcements
Mervon Mehta, Executive Director, RCM Performing Arts, has announced two more additions to the already exciting and diverse 2010.11 Koerner Hall concert season.
The Bacon Brothers have been playing music together since long before Kevin (yes, that Kevin Bacon!) started his acting career and his brother, Michael, became an award-winning composer for the film industry. The brothers will bring their trademark rock-folk to The Royal Conservatory's Koerner Hall on February 3, 2010. The concert, originally planned to open the 2010.11 season on September 17, had to be rescheduled due to Kevin Bacon's casting in the upcoming X-Men movie that will be filming this fall.
In other updates, Canadian singer-songwriter Luke McMaster has just been added as an opening act for the American country-indie-folk singer Brandi Carlile on October 6, 2010, which will be the first concert of the 2010.11 season. McMaster, who participated in the Bluebird North events last season atThe Royal Conservatory, was one half of the Canadian gold-selling Sony/BMG-signed band, McMaster & James. He has since become a significant songwriter and producer, whose songs have become multi-platinum and gold sales for many of his collaborators such as Rihanna, Nick Lachey, Kyle Riabko, Bret Ryan, Rex Goudie, Kalan Porter, and Marc Jordan. Three of Mr. McMaster's songs are featured in the new feature film Degrassi Goes Hollywood, including the hit title track Life is a Show and, most recently, his song For the First Time was featured on TV during the Olympic Games.
Founded in 1886, The Royal Conservatory is the largest and oldest independent arts educator in Canada. It is an internationally-renowned centre for performance and learning, providing opportunities for personal development through music and arts education in over 300 communities across Canada and a dozen countries around the world. Each year, more than 500,000 Canadians take part in RCM programs, exams, and public school initiatives.
Brandi Carlile with special guest Luke McMaster: Wednesday, October 6, 2010 at 8:00pm
The Bacon Brothers: Thursday, February 3, 2011 at 8:00pm
Tickets for Koerner Hall concerts range from $20-$75, with premium tickets available upon request
Select any 4-6 concerts and save 10%; Select any 7+ concerts and save 15%
A limited number of $10 rush tickets are available starting 90 minutes
before all performances presented by The Royal Conservatory
All concerts take place at The Royal Conservatory
TELUS Centre for Performance and Learning, 273 Bloor Street West, Toronto
Tickets are available online at www.rcmusic.ca, by calling 416.408.0208,
or in person at the Weston Family Box Office


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We've seen spy shots of the X4 M last month and, more recently, the X3 M raiding the Nurburgring. Our spies have sent us yet another update on the high-performance crossover coupe and some new details have also surfaced.
There is now a clearer view of the enlarged front air intakes, giving it a more sporting and aggressive character. At the same time, we now see that the X4 M employes side mounted intercoolers which peek through the corner intakes. It also appears that it will get some form adaptive cruise control function, as seen by a sensor at the lower half of the bumper.
Curiously, this particular test car sports a different wheel and tire combination. The old car shod Bridgestone tires while the new one comes with Michelins, presumably a set of Pilot Sport 4s. This set on the test car appears to be wider than those on the older test unit. Also, the pair of mismatched rims hint some of its wheel options one the car is out in the market. This being an M car, cross-drilled brakes are present on all four corners.
Moving to the rear, the X4 M gets a set of large, quad exhaust tips, and prominent lip spoilers on two parts of the rear hatch. With the X4 getting re-engineered by the M Division, it is upright sibling, the X3 also gets the same treatment. The 2018 BMW X4 M has also been christened with the chassis code F98.
As mentioned before, our spies say that it will be a new engine dubbed the S58. The straight-six engine is boosted by two turbochargers with power output is pegged at 450 PS. xDrive all-wheel drive will be standard and likely to have been recalibrated for the car's purpose.
The 2018 BMW X4 M is set to make its public debut during the first half of next year.


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August 20th, 2012 - By handjobhubster
Content Quality
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Reviewed Site Details
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Wmv, Mpeg
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Bonus Sites:
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29.90 for 30 days
$29.90 for 30 days
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Our Review of Hand Domination
HandDomination.com definitely gives away a major aspect of the website in its name. The females are the controlling sex in the handjob porn videos and are quite verbally and physically demanding of the cocks their hands grasp. Speaking to the man that is receiving the wank and letting him know that she is in charge is a common theme among the high quality videos. Teasing, denial, and humiliation are all part of the handjob experience at HandDomination.com. If you enjoy hand job videos and authoritative women, you're in for a real treat and double your pleasure.
There are a variety of amateur girls featured in the videos at HandDomination.com with some well-known names mixed in. Perhaps you've heard of Riley Brooke, Shyla Shy, and Bella Blaze who all bring a big set of tits to the handjob videos they star in. If you prefer getting jerked off by MILFs than you may enjoy videos from Grace Evangeline, Sierra Lynx, and Stacie Starr. There are also dominating women who bring a little BDSM to the handjobs like Audrey Lords and Mistress Laura. Both the amateurs and known models all bring something special and unique to each of the jerking porn videos.
Before joining the site you're able to view all the model's available in the member's area that have made handjob videos. At last count there are 117 different models of varying age, race, and body type. Each model has their own bio page that lists their age, bra size, orientation, location, and even their marital status. The bio pages also feature short Q and A interviews, a model description, and the scenes the model appears in. The amount of information available about the models before even joining as a member is a real plus and very well-done. You know exactly what you're getting and what to expect before you purchase a subscription.
Let's not forget about the men and the cocks that are getting jerked off! You're able to see every cock that gets wanked in the screen shots from the videos, but HandDomination.com goes a bit further and has even measured each individual cock that makes it into one of their handjob porn videos. The size range of dicks available is from 6 inches to 13 inches in length. Obviously some cocks will require two hands and others will face the humiliation of just one.
Details about the type of handjob videos available to members are found on each separate video page, but also in the about section of the website. Femdom handjobs, CBT handjobs, gloryhole handjobs, and masturbation instructional handjobs are just a few of the handjob related niches listed. There is a true dedication to the art of the hand job at HandDomination.com which makes being a member not only a pleasurable experience, but one that's actually worth the money! The fact that they speak of handjobs as an art speaks volumes in itself.
Another great advantage to customers of HandDomination.com is being able to see details about every handjob video available in the member's area. There are screen caps of each video showing the girl and the cock she's wanking. Descriptions of each video are also posted along with the date of the hand job video and the duration. You can even watch sample trailers of every video HandDomination.com has on their website. The videos range from around 12 minutes to 20 minutes long each.
There are nearly 200 videos available in the member's area of HandDomination.com. There is also a special cumshot section with the same amount of videos, but all with slow motion that feature the money shot of each handjob porn video. The video quality depends upon the date it was shot and ranges from good to high definition. Older videos are good quality and new videos are fantastic to watch in stunning quality.
You also get nearly 150 high-res sets of images with your membership to HandDomination.com. There are 40 beautiful pictures per set that really give you a unique view of the action. Beautiful close-ups are included in every set and make you feel like you're a part of the scene. Screen captures are also available for every video available in the member's section of HandDomination.com
There is a blog available at HandDomination.com that lists other reviews that were made about the website and information about the site itself. It hasn't been updated for nearly 2 years and appears they just don't have the time to keep up with it any longer. It is obviously the focus on website updates and new videos that has distracted them from the blog. So, it's not necessarily a bad thing that it hasn't seen any recent updates.
HandDomination.com has been steadily updating videos every week for over 5 years now. They originally started in April of 2007 and are still updating with new handjob videos today. The updates are always high quality erotic handjob videos that seem to get better as each week goes by. You will definitely be sitting on the edge of your seat every week waiting for the next update!


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Social petworking – believe it or not it's a real thing. Not only is it real, it's growing at a phenomenal rate.
If this is as new a topic as it was to me a few months ago, then let me introduce you to some of the sites leading the way.
First of all we have My Social Petwork – the Instagram of the animal world if you like. This network is based on our love for those cute doggy snaps and the videos of kittens doing crazy things that we just can't take our eyes off of. Users rate photos and videos of people's pets (and there really is a whole array – giant snails feature on the home page…) with the aim to become the highest rated photo or video of the day. If we look at the activity all over our Facebook feeds, it is quite clear there's an audience for this type of community. And I'm just talking about the owners – thats not including the 1 in 10 social profiles that are actually for pets themselves. If you're not familiar with it, take a look at Boo's profile – the most popular dog on the planet, or so the 7.3 million likes would suggest.
Then we have the interestingly named Yummy Pets – the self proclaimed Facebook for pets. This takes it up a level – owners are no longer owners but indeed 'pet parents'. I think there's a lot to be improved on the branding ('click here to discover yummy pets' seems a somewhat strange invitation), but with 150,000 members, there's no arguing its popularity. The community is very much built around what we are used to seeing on the 'human side' of social – profiles, status updates, photos, and lists of friends and fans. Having started life in France and launching this year in the UK, it's certainly a booming business.
Now I'm no huge animal lover, but I do love social media, and I get where this adds value. There's clearly a lot of pet owners with a whole lot of time on their hands, and that's no bad thing for the petworking community, but where the value is really added is when these communities can be used as a resource for improving pet care. As examples, the sponsored ads within Yummy Pets take people to practical pet services, the blog provides helpful updates on keeping your pet healthy and of course the VIPets section – it's always vital to keep up to date with celeb pets…
So my conclusion on the trend that I was initially pretty skeptical about is that it makes complete sense. As a generation we love social media, as a global population we love our pets, ergo we love social petworking. And if you're still not sold – take a look at this infographic on the top social networking stars (the numbers are a little outdated, but they are still very much stars). Engagement numbers we could only ever dream of!
Read, love, share.


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The picture – Mary Magdalene
The author and mystic Lars Muhl received a picture from a friend in 1983; philosopher John Engelbrecht, was able to report that it was "channeled" down by three clairvoyant monks and represented Mary, the virgin.
Later, just before Lars Muhl's book Mary Magdalene was being produced, Lars placed the picture on the last page of the book. He was convinced that the image of the equally looked like Mary Magdalene, but since he had no tangible proof, he placed it without giving details. The picture was a kind of distress signal.
Abstract from the book Grail by Lars Muhl
(Reprinted in part with permission from the author)
During a lecture in the Theosophical Society in Copenhagen, an approximately 60-year-old gentleman asked Lars the following questions:
- You have brought this image in your new book with no title or explanation, from where do you have the picture and who is it?
The Lord himself could report that it was his mother who in 1960 brought home the image to Denmark and that it was channeled by three lucids. And the picture actually represented Mary Magdalene.
A week after the lecture the phone rang, it was the gentleman who told him that his mother was still alive and would like to meet him. The name was Sylvia. Lars received the address. Was it the same Sylvia, an English medium 23 years earlier had predicted Lars was going to meet, because Sylvia had something to tell Lars?
It turned out to be right. When Lars is visiting Sylvia, she says:
- It took you a long time - but better late than never. It's great to see you again.
And a little later, when they had cake and coffee.
- I have not yet read your books, but when my son showed me the picture of Mary Magdalene book, I was aware that the messenger, I've been waiting for in over 40 years would appear, has finally made themselves known. I was actually about to give up hope. The Board of Directors (the universe) know how often I have asked that you would show up. The Mary image has throughout acted as a kind of smoke signal.
With permission from the author and mystic Lars Muhl
the image of Mary Magdalene is used
in the Mary Magdalene Series graphic expression.
This has been given on the basis of Lars' deep commitment
in the genesis of the Mary Magdalene Oil and Balm.


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Serves six
For the pancakes
125g (4fl oz) plain flour
125g (4fl oz) buckwheat flour
1 tsp salt
300ml (10fl oz) milk
2 large eggs
30g (1¼oz) melted butter
groundnut oil, for frying
For the filling
65g (2½oz) butter
6 tbsp groundnut oil
4 large onions, very finely sliced
600g (1lb 4oz) mushrooms, field or button
2 cloves garlic, crushed
150g (5½oz) roquefort, crumbled
30g (1¾oz) toasted walnuts, chopped
1 tbsp finely chopped parsley
Sift the flours and salt into a bowl and make a well in the centre. In a jug, beat the milk and eggs with 100ml (3½fl oz) water and gradually pour into the well, whisking until completely smooth. Stir in the melted butter and leave to rest for half an hour.
Heat 50g (1¾oz) of the butter and 2 tbsp of the oil in a large pan and stir the onions in it. Add 2 tbsp water, then cover the pan and let the onions sweat over a very low heat, stirring from time to time to prevent burning. After half an hour remove the lid and cook for a further half hour, stirring now and then. The onions should darken and caramelise. If they still seem moist and are not caramelising, turn up the heat to drive off some of the liquid. Season.
Slice any big field mushrooms and quarter or halve any button. Heat half the remaining oil in a frying-pan and briskly sauté half the mushrooms until golden. They will throw out a lot of liquid – cook it all off. Set aside, and repeat with the rest. Put them all back in the pan, add the garlic and the remaining butter and cook for a couple of minutes. Season well.
To make the galettes heat about ½ tbsp groundnut oil in a large non-stick frying-pan. Add half a ladleful of batter and swirl it round to cover the base. The batter is thick so it takes a bit of effort, though the pancake itself should be only slightly thicker than a crêpe. Cook until brown and set underneath then flip and cook the other side. Add a tiny bit more oil for each new pancake.
Quickly reheat the onions and mushrooms. Scatter each pancake with onions, mushrooms, cheese, walnuts and parsley. You can fold them in half like an omelette, or fold in the sides to make a square package with the filling peeking out. I prefer the latter.


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As if the Sunday Assembly with Danny Bent wasn't enough!
Sunday Assembly and Project Awesome are having a mash up and the results are going to be beautiful!
Come along to the Assembly on the 4 September (wearing your most brilliant of 80s workout outfits) and come and take part in a Project Awesome afterwards!
The Project Awesome session after the assembly is for EVERYONE!! Whether you are looking for something to get you off the couch or whether you're building for Tokyo 2020 - it literally caters for all! Bring it on!
(This is a rare opportunity to experience the brilliance of Project Awesome without having to get up before 6:30am!)
We can't wait to celebrate life with some fitness as well as singing and inspiration.
Here's some more information about Project Awesome: http://www.projectawesomehq.com/about-us/


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Tapioca Starch Tableware
Bamblu offers you only eco-friendly and compostable tableware. A fairly new product on our planet, tapioca starch (and a wee bit of bamboo fiber) is hard to find and stock is limited. The idea of Bamblu began with this lovely disposable tableware by Blueware, rebranded and sold throughout the U.S. at Whole Foods. Bamblu no longer rebrands as our own, but this lovely tableware is why Bamblu Panda is eating a blue plate. Certifications and exactly what they are made of is provided on the product's page and on our product spec page. You might check out Bamblu's color chart, too. Be sure to check out Bamblu's colorful Green Party Cutlery to coordinate with your theme.


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Getty Images
Saturday, July 18, 2009
Poppy Delevigne at the Chanel Haute Couture show in Paris earlier this month. So pretty!
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