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3d Interior Design Software
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SketchUp for Interior DesignA practical guide to SketchUp addressing the specific needs of interior designersAlready a common and popular tool for architects and landscape architects, SketchUp is increasingly finding a place in the professional workflow of interior designers. SketchUp for Interior Design is a practical introduction for interior designers and students who want to learn to use the software for their unique needs. The book covers the basics of creating 3D models before showing how to create space plans, model... read more Hide
TurboCAD 3D Interior Symbols PackAutomatically add 3D symbols to your TurboCAD designs with TurboCAD 3D Interior Symbols Pack. Specifically designed to make designs more lifelike, the Symbols Pack is a valuable, time-saving design application. Simply select the 3D symbol you want without leaving TurboCAD! read more Hide
3D Symbols Interior [Licence - ESD Windows]Automatically add 3D symbols to your TurboCAD designs with TurboCAD 3D Exterior Symbols Pack. Specifically designed to make designs more lifelike, the Symbols Pack is a valuable, time-saving design application. Simply select the 3D symbol you want without leaving TurboCAD! read more Hide
Interior Design Business PlanBarton Interiors is an interior design service for discerning, quality-conscious clients that seek assistance in their design choices for their primary residences, vacation homes, and businesses. This experience offers personal attention through the design process and also provides design resources and products to its clients through special purchases of furniture, fabric, and accessories. The total experience is provided in a way to inform, inspire, and assist people through the process of transforming... read more Hide
SketchUp for Interior DesignA practical guide to SketchUp addressing the specific needs of interior designers Already a common and popular tool for architects and landscape architects, SketchUp is increasingly finding a place in the professional workflow of interior designers. SketchUp for Interior Design is a practical introduction for interior designers and students who want to learn to use the software for their unique needs. The book covers the basics of creating 3D models before showing how to create space plans, model... read more Hide
Get the power of AutoCAD® software, plus tools to help you capture and showcase your 3D designsAutoCAD Design Suite Premium 2015 Get the power of AutoCAD® software, plus tools to help you capture and showcase your 3D designs. Did you know ? This product is now also available as a Desktop Subscription. Learn more here. Choose Your Product Configuration: Click to reset your product configuration New Seat or Upgrade Select One New Seat Upgrade Delivery Method Select One Languages Select One Adding to Cart... read more Hide
Luxe Interiors & DesignLuxe. Interiors + Design Magazine is the uncompromised source for those with a passion for creating beautiful surroundings and living well. It is the go-to guide and resource for design, decorating, architecture and renovation. Edited for the affluent, sophisticated homeowner, luxe. interiors + design is the only luxury publication that offers access to the local design and architecture scene, while also covering national design news and trends. The Luxe. interiors + design network and its influence... read more Hide
Livable Modernism: Interior Decorating and Design During the GreatLivable Modernism: Interior Decorating and Design During the Great
Avanquest TurboCAD Deluxe 2D/3D - 2013For precise and accurate drafting and modelling, try Avenquest's TurboCAD Deluxe 2D/3D - 2013 for a well rounded and versatile design programme. Truly compatible Containing everything you need to put together detailed technical illustrations and textured models, TurboCAD 2013 is a complete design and drafting package. Compatible with both 32 & 64-Bit systems, you can create in-depth and clearly annotated 2D plans and 3D models for a variety of different applications. Professional designs, mechanical... read more Hide
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Electronic Workflow for Interior Designers and ArchitectsThis book examines how different software can be incorporated into the traditional phases of an interior design project and demonstrates technical tactics within those programs to optimise workflow and interoperability. It is not a technical reference manual for any of the software packages described - the goal is for students to develop a basic working knowledge of the most commonly used software and the skills to create professional electronic presentations. Just as the techniques of using a paint... read more Hide
Focus Multimedia :: By Brand :: Essential :: Total CAD 2D-3D Version 2 - PC CD/DVD-ROM softwarePerfect for novice and expert users. Dozens of drawing tools, easy file sharing and an intuitive interface. Metric and imperial units of measure. Over 10,000 2D/3D symbols to quickly drag and drop into your design. Over 150 drawing, editing and viewing tools. Unlimited undo and layers. 3D texture mapping and smooth anti-aliased rendering. Easily import/export editable AutoCAD DXF/DWG files. Tip of the Day. Plus much more!. read more Hide
PANTONEVIEW home + interiors 2015 trend forecast1" x 4" cotton swatch strips of each of the 72 forecasted colours. Detachable printed colour card of each trend palette. PANTONE COLOR MANAGER software for digital design. CMYK values of each of the forecasted colours. DVD containing still images of photos used to illustrate individual trend palettes. Summary Page highlighting additional key colour insights and direction. read more Hide
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Viewsonic PJD5133 3D DLP ProjectorThe ViewSonic® PJD5133 is a high-performance SVGA 800x600 DLP® projector with 2700 ANSI lumens and 3000:1 contrast ratio. With new slim design at only 3.2 inches high, makes it ideal to move from room to room on campus or throughout the office. This projector offers a variety of hardware and software features including HDMI, multiple PC and video input options, 1.1x manual optical zoom, vertical keystone correction, 120Hz/3D-ready, support HD video signal and integrated speaker... read more Hide
Tria Marker 24 Collection + Wallet Interior DesignColour:Multi. Pack Size:24. Type:Pen. Ink Type:Alcohol Based. Nib Type:Multi Nib.
Brother PE Design Next SoftwareOnly £599.00 when purchased with a Brother Embroidery Machine. Save £400.00. Brother PE DESIGN® NEXT takes digitising and embroidery to the next level of creativity with exceptional new features. A user-friendly graphical interface, similar to many software programs on the market today, makes it easy to locate and select the dynamic functions of this software. In addition, the quick access toolbar allows you to customise your favourite operations so they are only a quick click away. Several "Start... read more Hide
A1 Interior Design PackConsists of1 off A2 Super Desk top drawing board1 off 6 piece Helix Drawing set1 off 45 degree Helix set square1 off 60 degree Helix set square1 off Helix Eraser1 off Helix Triangular Scale Ruler.This portable drawing board unit of high quality has a back stand manufactured from steel. The drawing boards have a six position tilt angle and are able to fold completely flat if required. The impact resistant drawing surface has a stylish 3mm thick P.V.C.edging for hard use environments. Drawing unit... read more Hide
Card Studio Classic Card Design SoftwareIf a product is showing as "Stock not available" this means the datafeed from one of our suppliers is showing zero stock on the last update. However, this does not necessarily mean we cannot source the product from another supplier quickly so please email firstname.lastname@example.com or use the Live Chat facility to check a specific product availability. read more Hide
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Location 17 South Virginia Street Reno, NV 89501 Get Directions |
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Creative Casual Cuisine.
Incredible hand-crafted cocktails.
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Located on the RiverWalk in Downtown Reno, Wild River Grille is a contemporary restaurant with nature-inspired influences, a full bar and expansive riverside patio. Situated in the Riverside Artist Lofts Building just across Virginia Street from the Pioneer Theatre, we're serving lunch and dinner 7 days a week starting at 11:00 am. Our dining menu features both traditional and innovative cuisine, while our bar prepares incredible hand-crafted cocktails featuring fresh squeezed juices and liquor infusions.
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AMBIANCE: Contemporary with nature-inspired influences
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GAMING: We offer gaming at our new bar-top Game King Machine
February 2
Reno-Tahoe Senior Winter Games
The Reno Tahoe Senior Games is a program dedicated to promotiong and implementing fitness...
February 13
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Sample more than 150 types of beer while enjoying great live music. Over 20 local and regional...
February 14
Valentine's Pajama Crawl
Have you ever been out with your friends, yet wished you were all cozy at home wrapped in your...


text: while I'm in Florida. Great food, great service and great atmosphere. We were able to dine here twice while in town and are coming back in February so we can try the mussels. The Escargot is to die for!!! An old family recipe I was told and can verify it is the best I have every had! Truly authentic Italian... More


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The Royals
Royal Mad Hatters!
The pomp! The pageantry! See the parade of head-turning toppers fit for the Queen and her royal court
Credit: Samir Hussein/WireImage
Updated: Wednesday Apr 20, 2011 | 06:00 AM EDT By: Julia Wang
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- What Would Chris Kyle Really Think of American Sniper?


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A YGO dueling academy that seeks to have a nice clean communitywhere all could have fun and compete in same time.
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Marauders Era Alternate Universe RPG, Enter a Universe you have not yet explored. Attend Hogwarts or our very own Unique school, WolfClaw Academy of Magic, Join as an Original Character or Canon Character. Attend Classes, get a job and start working
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where eating a dragon is only your first test the second is becoming one
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Official forums for the visual novel, Starswirl Academy.
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XML Software
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RealmForge (now Visual3D Game Engine) The first 3D game engine built in C# for .NET, predecessor to the Visual3D Game Engine (http://www.visual3d.net/game-engine), an All-in-One Game Development Tool for Next-Gen 3D Games, MMOs, Simulations and Virtual Worlds powered by Microsoft XNA.
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XML comparator XML comparator. Compare two XML files, or text inputs and show highlighted differences. Nodes are closable/expandable, like do browsers. XML Comparator is web application based on Java/Struts.
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Learning Object Metadata (LOM) Java API This is a Java API binding of the IEEE LTSC LOM (Learning Object Metadata) specification. It defines an implementation neutral Java interface for the LOM, as well as providing a default implementation of that interface, and XML marshalling functionality
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tbook -- Document Preparation with XML This project hast moved to <https://launchpad.net/tbook>. It is currently inactive.
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RSS Framework for PHP This framework written in object oriented PHP4 can create RSS 2.0 feeds. Because the transformation from objects to RSS feed happens via XSLT, you can just as well transform the objects into whatever you want, if you have your own transformation file.
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Simple effective XML Using XML on any platform should be sexily easy. It should be possible to transform between all the major formats: ATOM, RSS 0.9x, RSS 1, RSS 2, xHTML, etc and it should be easy to use FOAFROLL and OPML as well. Our aim is to facilitate that.
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VDEX Java Binding This is a Java API binding of the IMS VDEX (Vocabulary Definition Exchange) specification. It defines an implementation neutral Java interface for VDEX, as well as providing a default implementation of that interface, and XML marshalling functionality.
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pilot-qof pilot-qof provides a query interface to data on a Palm device, using pilot-link and QOF - the Query Object Framework. pilot-qof supports reading addressbook, datebook, expenses and ToDo data and runs SQL-type queries on the live data or a QSF XML fil
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COLLADA plugin for OpenSceneGraph NOTE: As of August 2006, development of this COLLADA plugin has migrated into the official OpenSceneGraph repository, so this SourceForge project is frozen for historical reference only. See http://openscenegraph.org/
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CrazyBeavers Chat Webbased chat application. Working against an ASP webservice using XML data format and Javascript.
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OpenOffice.org XSLT Filters It's a open source incubating project of creating XSLT filters for OpenOffice.org, providing import/export abilities of OOo with other open standards or (information visual) file formats, e.g. Open eBook, XBRL, Diasy Book, RSS, financial reports, research
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Poor Xml Wrapper 4 Php Arrays pXw4Pa (poor XML wrapper for PHP arrays) are 2 simple php functions written with php4.3.7 that can read/write a php array from/to an xml file. Can be used to store data on xml files simply and fast, without to make use of others big stuff.
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Team preview: Louisiana Tech
Blue Ribbon Illustrated previews the 2003-04 college basketball season, exclusively on Insider.
Updated: November 4, 2003, 5:56 PM ET
Blue Ribbon Yearbook
Editor's Note: Insider has teamed with Blue Ribbon College Basketball Yearbook, long known as the Bible of college basketball, to provide a comprehensive look at all 327 Division I teams.
The biggest disappointment in the Western Athletic Conference last year had to be Louisiana Tech. Coming off a 22-win season and a great run in the postseason NIT that led to a preseason appearance last year, the Bulldogs seemed poised for an NCAA Tournament run.
Nothing could have been farther from the truth.
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- Xavier completes sweep of No. 21 G'town
- Oklahoma State takes down No. 20 Baylor
- UW dismisses Upshaw for violating team rules
- Unbeatens Kentucky, Virginia still atop AP poll
- VCU Keeps Rolling
- VCU won its 12th in a row and is building toward March.
Brown »
- Brogdon's Big Role With UVa
- Malcolm Brogdon's game and mind a big reason Virginia is undefeated.
Power Rankings »
- The Big 12 Factor
- The Big 12 is playing havoc with our rankings. Just take a look.
Power Rankings »
- Lange: Week's best college hoops bets
- Goodman: 10 coaches on the hot seat
- Lunardi: Why St. John's won't make tourney
- Farnham: Updated #NoLoveTeam
- Gasaway: Top 25 players in college basketball


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Rock drop close one in Philly
Kevin Crowley nets six for Wings. Garrett Billings leads Toronto offence.
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PHILADELPHIA—Kevin Crowley's sixth goal of the game at 5:53 of the fourth quarter put his club ahead for good as the Philadelphia Wings edged the visiting Toronto Rock 14-13 on Saturday in National Lacrosse League action.
Tracey Kelusky and Kyle Buchanan each had a pair of goals for the Wings (4-9), Ryan Ward had a goal and three assists and Garret Thul, Brodie Merrill and Pat Saunders added singles.
Philadelphia's Jordan Hall chipped in with five assists, while Crowley tacked on three for a nine-point performance.
Garrett Billings led the Rock (5-8) with three goals and seven assists. Rob Hellyer and Josh Anderson added three goals apiece. Sandy Chapman, Colin Doyle, Bill Greer and Scott Johnston had the others.
Evan Kirk and Kevin Croswell combined to stop 46 of 59 shots for the Wings. Toronto's Nick Rose gave up 14 goals on 58 shots.
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- Women's measurements
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- How many triangles?
- Pythagoras - three is the perfect number
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- Three Foil Cross
- Teeth
- Three Holy sites of Islam
- Periodic Table - Law of Triads
Ceratium tripos |
Art - Design | |||
Ceratium tripos, Gulf Stream and Tampa Bay
Sharyn Hedrick Digital photograph 2005 Environmental Research Center, Phytoplankton Ecology Phytoplankton from the Chesapeake Bay and Other Regions around the World Accession no. FLRcertrip051028 This photograph was taken with an Olympus DP12 digital camera attached to an Olympus IX71 phase contrast microscope.
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The bagel aficionados at Bagel World Caf? borrow the dual techniques of baking and boiling their signature breakfast staple from The Big Apple. Every day at their four locations, they whip up batches of fresh bagels in more than 23 flavors, such as cinnamon crunch and jalapeno bialy. But it's not just the bagels that are made fresh daily?everything from their macaroni to their 12 flavors of house-made cream cheese, available in flavors from honey vanilla to cheesecake, complement each bagel. Bagel World's sub and Kaiser rolls are likewise baked daily, rather than hastily assembled by squishing leftover bagels together. They serve as the foundation to half-pound sandwiches made with Boar's Head meats such as corned beef and cracked pepper turkey. All these can be washed down with coffee brewed from house-roasted beans or freshly-made smoothies.
Alpine Yogurt Cafe is the newest frozen yogurt shop on the beach. We serve all natural low-fat/fat-free frozen yogurt and sorbet with over 35 toppings to choose from. Come in for a wintry frozen treat, enjoy our free high-speed wifi, and relax with friends in a trendy atmosphere.
With iridescent miniature golf courses in malls throughout North America, Glowgolf adds elements of phosphorescent fun to shopping sessions. Courses contain sights such as light-defying blush corals, incandescent animals, and lush foliage reminiscent of the glowing trees on Neptune. Each pass is good for three 18-hole games, giving golfers ample opportunity to get familiar with each hole's obstacles. Equipment is available on the spot, so players won't have to carry around personal clubs or seek out a bioluminescent caddie.
The crew at Mister Beaujeans Ice Cream Company is committed to crafting soft-serve ice-cream treats and American fare with wholesome ingredients and minimal environmental impact. They combine all-natural cream, vanilla beans, pure Belgian chocolate, and evaporated sugar cane juice to make rich ice cream, and utilize certified carbon-free cane sugar and renewable products as part of an eco-friendly philosophy. Staffers dress up cups and cones with seven types of syrup and rainbow sprinkles that guests can separate into neatly color-coded piles.
For lunch and dinner, cooks steam cheeseburgers and deep-fry hot dogs, serving them on house-made buns alongside razor fries in flavors such as salt and vinegar. Early morning patrons can get their hands on breakfast sandwiches, waffles with house-made caramel syrup, or handmade beignets with cinnamon sugar, while they last.
Chilly Spoons tempts sweet teeth with ten frozen yogurt dispensers that send out swirls of 100 rotating flavors and a few popular staples every day, including options that contain no fat, no dairy products, and no sugar added. After filling their cups, guests can customize their treats with more than 80 toppings that include candy, syrups, and fresh fruit, forming combos such as no-sugar-added coffee frozen yogurt with Kit Kats, Reese?s Pieces, and coconut flakes or tart wildberry frozen yogurt with slices of strawberries, almonds, and mochi. Since every treat is priced by the ounce, guests can also adjust their frozen yogurt?s size, grabbing a little for a guilt-free snack or a lot to add realism to a North Pole diorama.
The staff at Chilly Spoon's Melbourne location are dedicated to providing the community with more than just sweet treats: They've outfitted the eatery with a private kid's room that keeps little ones entertained with a television and a giant whiteboard, which serves as a canvas for budding artists. They also host events that take place in-store and outside, hosting birthday celebrations, Girl Scout field trips, and bounce-house parties.
Cathy Morris has spent 35 years of running restaurants, and she knows how to keep her customers happy. At Swagger's Southern Style Eatery, where she mans the griddle as the owner and operator, she'll cook you a burger in the morning or a three-egg omelet at lunch, as breakfast is served till 3 p.m.?whatever the meal, no one goes home hungry. That is especially the case with the breakfast specialty platter The Lumberjack, with two eggs, two pancakes, three meats, and home fries, as well as with The Bunkhouse, a five-ounce sirloin served alongside eggs and a camp counselor that makes sure you're asleep before 10 p.m.
The lunch and dinner options are equally enticing: Soups and salads balance out entrees such as Southern-fried smoked chicken and homemade meatloaf with red sauce. Bookending the main courses are appetizers such as hot wings and desserts such as homemade cobbler, bookend the main courses.


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VIRAL VIDEOS: Week of October 26th
Audio clip:
Here's what's going viral now on Facebook.
"Child Actor Henry Thomas's Audition."
Coinciding with the 30th anniversary of Steven Spielberg's E.T. The Extra-Terrestrial, this vintage video is now making the rounds. It shows a young Henry Thomas trying-out for the part of Elliot, with an improvisation scene that's a real tear-jerker… earning Spielberg's seal of approval.
Then, there's this:
"Pumpkin Carving IV."
For the fourth consecutive year, fire arms lover Bill Hickok shows the Internet a less messy way to carve a pumpkin. Ditching a serrated knife for a handgun, this clip shows Hickok using a Colt 1911 to create a jack o' lantern … carefully pumping the pumpkin with lead to create a face.
And, Facebook users are hitting the "like" button on:
"Iron Man 3 Trailer."
The action-packed clip shows Robert Downey Junior reprising his role as the brilliant billionaire super hero Tony Stark, who faces an attack on his seaside home, exploding Iron Man suits and a new villain…. the Mandarin, played by Sir Ben Kingsley. The movie hits theaters this May.
For these videos and more, go to foxnewsradio.com
I'm Lauren Faulkner and those are your Facebook Status Updates on FOX News Radio.
Follow Lauren on Twitter: @FaulknerFOXNews


text: Share: Free Range or Free Roaming The poultry was not confined to a chicken house but was allowed outside to forage for food. Related Tips Soft-Ripened Cheeses Cheese ripened with bacteria, which may have a creamy—and sometimes… Water Bath To place a baking dish containing food, such as a custard or souffle, in a large dish. The… Core To remove the seed area of an apple or pear using a coring tool or a small knife.


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Balboa Park: The Magic City
Scott Ellis 10:13 p.m., Jan. 27
"Do you have Mexican food in Vancouver? Wait, that's a stupid question — it's a city, of course you do," I said. "But it's probably not as good as it is here...I mean, not because ...
Scott Ellis 10:13 p.m., Jan. 27
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For some time I have been looking at the possibility to integrate PowerShell as a scripting engine in SharePoint but I haven't found the right solution yet.
My main objective is to enable event triggers in e.g. a list to call and execute a PowerShell script (by filename) on the local server. This would give me a lot of flexibility compared to using an ordinary event handler written in visual studio, but the question is whether it is possible and whether I have overlooked some serious security issues?
Since each and every unique idea that I come up with in many years have already be invented by somebody else, I might have missed an existing product/project so any links to such projects will be appreciated, thanks


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Looking at upgrading my brakes to the 2005 XTR. Do these brakes still have sticky piston as noted by MANY reviews???
Also, I'm thikning of running the same brakes with two wheels sets. Rhyno Lite on Deores as a training set, and XT on 717 as my race wheel. How easy is the adjustment after wheel switching?? I obviously need two set of rotors
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When archaeologist Louise Cantor's son Henrik is found dead in his flat, she refuses to believe it was suicide. Clues that only a mother could detect lead her to believe something more sinister took place. Henrik had kept many things back from her and she is shocked to learn he had contracted HIV. While looking through his bundles of papers, she ... Read More When archaeologist Louise Cantor's son Henrik is found dead in his flat, she refuses to believe it was suicide. Clues that only a mother could detect lead her to believe something more sinister took place. Henrik had kept many things back from her and she is shocked to learn he had contracted HIV. While looking through his bundles of papers, she discovers he was obsessed with the conspiracy theory that JFK's brain disappeared prior to the autopsy - along with the vital evidence regarding bullet exit wounds. The only lead is a letter and photograph from Henrik's girlfriend in Mozambique. Louise's quest to unravel the mystery surrounding her son's death takes her to Africa; a continent rife with disease, poverty and corruption. Struggling to cope with sickness and the oppressive heat, Louise sees fear in every face, even unexpectedly in the patients at the clinics set up by an American businessman. In "Kennedy's Brain" Mankell confirms his status as a master of suspense, and delivers a timely and riveting thriller which will have readers on the edge of their seats until the very end. Read Less
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Sep 28, 2007
Henning Mankell is absolutely one of my favorite authors. I love Kurt Wallander. Has Mankell pulled a John LeCarre'? Yes. The story about aids and the giant pharmaceuticals immorally profiting from their attempted cures is fast moving and well told. Mankell is obviously passionate about the subject which I respect. It does heighten ones awareness of the potential for very dangerous conflicts of interest. Beware the Good Samaritan is certainly a lesson we should all know to follow.The story is fast moving and the characters are interesting. Just be aware that this story is one of social consciousness and will not tie up in a nice knot for you.I am ready to get back to Kurt or Linda or Stefan.
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NSA given free rein in foreign spying
WASHINGTON — Virtually no foreign government is off-limits for the National Security Agency, which has been authorized to intercept information from individuals "concerning" all but four countries on Earth, according to top-secret documents.
The United States has long had broad no-spying arrangements with those four countries — Britain, Canada, Australia and New Zealand — in a group known collectively with the United States as the Five Eyes. But a classified 2010 legal certification and other documents indicate the NSA has been given a far more elastic authority than previously known, one that allows it to intercept through U.S. companies not just the communications of its overseas targets but any communications about its targets.
The certification — included among a set of documents leaked by former NSA contractor Edward Snowden — lists 193 countries that would be of valid interest for intelligence. The certification permitted the agency to gather intelligence about entities such as the International Monetary Fund, European Union and International Atomic Energy Agency.
The NSA is not necessarily targeting all the countries or organizations identified in the certification, affidavits and an accompanying exhibit; it has only been given authority to do so. The privacy implications are far-reaching, civil liberties advocates say, because of the wide spectrum of people who might be engaged in communication about foreign governments and entities.
"These documents show the potential scope of the government's surveillance activities and the exceedingly modest role the court plays in overseeing them," said Jameel Jaffer, deputy legal director of the American Civil Liberties Union, who had the documents described to him.
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Relevant offers
KiwiRail has upgraded a West Coast railway level crossing, but there are still 65 crossings in the region only controlled by signs.
There have been fatal accidents at two of those crossings this year.
Jane Sluys, 56, died on January 23 when her car was hit by a coal train at a crossing with Swamp Creek Rd, and Reefton couple Robert James Jacobs, 66, and Marieta Ocba Jacobs, 43, died on May 21 when their car was hit by a coal train at a crossing on Landing Creek Rd.
The accidents happened within two kilometres of each other.
Over the past decade, more than half of all accidents at railway crossings occurred at crossings where there were only signs, with no bells, lights or barrier arms.
KiwiRail has 97 public-road level crossings on the West Coast. Five have barriers plus lights and bells, 27 have lights and bells, but the remaining 65 only have stop or give-way signs.
KiwiRail chief executive Peter Reidy today visited the latest upgraded crossing on SH67 to reiterate safety messages around the crossings.
"Motorists should always be prepared to stop when approaching a level crossing and look in both directions to check the way is clear," he said.
"What most people don't realise is that it can take a train up to a kilometre to come to a stop."
KiwiRail uses the Australian Level Crossing Assessment Model (ALCAM) to evaluate risk and identify crossings that require safety improvements.
There are 63 road crossings and 110 pedestrian crossings on KiwiRail's priority list for improvements. It aimed to complete eight major upgrades annually - such upgrades could mean adding lights and bells at a crossing currently controlled by signs, or barrier arms at crossings that already have lights and bells.
The Swamp Creek and Landings Creek roads crossings, where Sluys and the Jacobs died, both have low traffic volumes so they do not rate highly on the ALCAM risk assessment.
Neither of the crossings were being considered for safety upgrades.
- Jane Sluys, 56, was hit by a coal train at a crossing with Swamp Creek Rd near Reefton on January 23. She died in hospital about a week later. She was driving from her home on Swamp Creek Rd. The level crossing has a stop sign and railway crossing signs.
- Cory Clements, 28, from Hamilton, died on February 27 when his truck was hit by a passenger train in Waikato. The Te Onetea Rd crossing has a stop sign and railway crossing signs.
- Reefton couple Robert James Jacobs, 66, and Marieta Ocba Jacobs, 43, died on May 21 when their car was hit by a coal train at a crossing north of Reefton. The Landing Creek Rd crossing was less than two kilometres from where Jane Sluys died four months earlier. The crossing has a give way sign and railway crossing signs.
In 2013 there were 18 accidents at level crossings - two motorists and one pedestrian died.
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Crime stopper Justine dials-in Gosnells fatal hit and run
When Justine Bucktrout noticed her neighbour slumped over the steering wheel of his damaged car, she knew something was wrong.
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"We were reversing out of the driveway and we could see the car all smashed up, he was sort of like slumped over in the front seat and on the steering, and I told him [her partner] to stop so I could go check him but as we were about to he looked up at us," Ms Bucktrout told Geoff Hutchison on 720 Mornings.
After she made eye contact with him, Ms Bucktrout assumed he was not badly injured. Soon after, Ms Bucktrout heard there had been a hit and run in the area and she became increasingly anxious as the pieces of the story came together.
"By the time the five O'clock news came on, they were giving a description of the car and I thought, 'Oh my goodness, I think that's his car, I think it was him,' and I rang crime stoppers for that."
A 56-year-old, Mr Mead, was killed on Ashburton Drive as he walked to buy the newspaper yesterday morning, which he did every morning.
The car involved was found at a house in the suburb of Huntingdale overnight after the call was made to Crime Stoppers.
Police did not find anyone at the property but early this morning a 39-year-old man handed himself in and he is now speaking to the Major Crime Squad.
"I was watching the family on the news and all I could think of was, 'What if he could have just stopped and rang an ambulance - maybe he'd still be alive'."
Police also discovered a drug lab inside the Homes West property where a couple and two children were living, which shocked Ms Bucktrout.
"I was just gobsmacked, I couldn't believe it... To have a drug lab in the middle of all these homes with kids in it, freaked me right out - completely freaked me out. "
A spokesperson for The Minister for Housing, Troy Buswell, said immediate steps would be taken to evict the tenants of the Homes West property.
To report a crime, visit the Crime Stoppers WA website or call 1800 333 000.
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To all Woolards, I am traveling through souther Illinios in September 2008. Does anyone know a cemtery around Raleigh, Saline County, Illinois, where Woolards are buried. I was there in June of this year and after looking in five separate cemeteries, I could not find any Woolards. Any help would be appreciated. Billy McCain, a great grandson of William A. Woolard. Notify Administrator about this message?
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Reviews for I Love Sushi
Back to the restaurant's page
Latest MenuPix Reviews
Kyle andover posted on 09/30/2014
Rating & Review:
I only give it a one star because there isn't a zero. The staff sucks. The owner sucks and the sushi quality is marginal at best. From the moment you walk in you feel rushed and that your presence is an inconvenience to them. You can FEEL them hovering close by and from and far and NOT to provide high quality attention; but rather to quickly fill your seat. Spicy tuna just down the street is much more li k ed for their friendliness and the extreme high quality of their product and service. I recommend you steer clear of this place.
Jen posted on 08/09/2009
Rating & Review:
excellent sushi one of theee best places in vegas
Latest Yelp Reviews
Overall Rating:
Based on 497 Reviews
Based on 497 Reviews
Angela D. posted on 01/17/2015
Rating & Review:
JB is an amazing artist in sushi creating! Our entire meal is living art!
So so so happy with this meal.
Amazing service, Amazing food, Amazing company my... read more
MLee .. posted on 01/13/2015
Rating & Review:
This is my go-to restaurant if I'm craving Japanese cuisine. Very fresh, fast and friendly service. I usually order sashimi and non-riced items.
Some of... read more
Andrea H. posted on 01/11/2015
Rating & Review:
I give 5 + starts for the food, i always say i won't comeback because of the service, but then i go to other sushi place in town i regret not going to i... read more
Write a Review


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Choose this apartmentJust like home, with all the facilities you need
27-28 Philbeach Gardens, London, SW5 9EA, United Kingdom – Show map
The location was on a beautiful tree-lined street. It was an easy walk to the underground and local neighborhood. The staff was friendly and helpful!
United States of America
The front desk was friendly and the bathrooms are clean and new.
United States of America
Sunny and the rest of the staff was welcoming and accommodating! The location was a quick walk to the tube station, Earl's Court, a delightful district with a variety of dining and shopping available.
United States of America
Staff is very friendly and helpful. Also i had an issue with a light bulb burning out and it was taken care of right away. :-)
United States of America
I loved the location, it was very convenient.
United States of America
Honestly the only thing I liked was how close it was to a metro (underground/ tube) station.
United States of America
Great position, silence, really clean
kitchen location bathroom
The apartments are very close to Earls Court underground station which is a central location. The beds were comfortable and the shower was hot.
Friendly staff, good location, cheap relative to comparable studios
Dylan Apartments Earls Court is just a 3-minute walk from Earl's Court Exhibition Centre and Earl's Court Tube (underground) Station. These studio apartments have fully equipped kitchenettes.
On a quiet street, guests are less than a mile from the Olympia Exhibition Centre and the shops of Kensington High Street. The London's West End is a few stops on the Tube from Earl's Court Station.
The self-catering apartments each have an open plan living area with a flat-screen TV, a bathroom with a shower and a small kitchenette area with a fridge, oven, stove top and microwave.
Dylan Apartments Earls Court also has a lounge for guests to relax in, and a lift to all floors. There is a 24-hour grocery store close by.
The A4 road, linking to the M4 highway, is 1000 ft away for access to London Heathrow Airport.
We speak your language! Apartments: 40 This property has been on Booking.com since Jan 28, 2010.
Cards accepted at this property
Room Type | Max | |
Superior Single Studio | ||
Executive Double Studio | ||
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They speak your language!
Dylan Apartments Earls Court's staff speaks: English
Booking is safe
When you book with us your details are protected by a secure connection.
WiFi is available in all areas and is free of charge.
No parking available.
Vending Machine (drinks), Vending Machine (snacks), Tour Desk, Ticket Service, Baggage Storage, Concierge Service, Laundry, Fax/Photocopying
Safe, Non-smoking Rooms, Elevator, Heating, All Spaces Non-Smoking (public and private)
Cancellation and prepayment policies vary according to apartment type. Please enter the dates of your stay and check what conditions apply to your preferred room.
Children and Extra Beds
All children are welcome.
All children under 5 years stay free of charge when using existing beds.
There is no capacity for extra beds in the room.
Pets are not allowed.
Cards accepted at this property
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Based on 670 reviews
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St Giles London – St Giles Classic Hotel
Latest booking: 30 minutes ago There are 28 people looking at these apartments.
Dylan Apartments Kensington (60) Dylan Apartments Kensington (60) are less than 545 yards from Earls Court Exhibition Centre and Earl's Court subway station. The budget rooms each have a compact kitchenette.
Score from 375 reviews
Review score
Opposite Earl's Court Exhibition Centre, this hotel features rooms with private bathrooms at good rates.
Score from 2670 reviews
Review score
The W14 Hotel features award-winning, 3-star accommodations in London's Kensington district. Consisting of 4 Victorian town houses, it mixes contemporary décor with many traditional old features.
Score from 580 reviews
Great position, silence, really clean
Few pot in the kitcen
The apartments are very close to Earls Court underground station which is a central location. The beds were comfortable and the shower was hot.
Very small compact kitchen which had limited utensils.
Friendly staff, good location, cheap relative to comparable studios
Very limited cooking utilities
Location was good
For the price I paid im very unimpressed with the quality of the room I had. Wifi was shockingly bad. Room had no working light switch (the key card box was the switch) really thin walls so could hear the noisy couple next door. Tiles in bathroom cracked and just generally not a nice place to stay for the money.
Only the hotel position is good and nothing else. In the case you want to stay in this zone I suggest to book another Hotel!
Room dimensions: only 7,5square meters! Ridiculous No hair dryer available . Shower not working No air vortex in the bathroom , this mean That All smells remain in the room!
the room was so small you couldnt move was not clean just would avoid altogether
price, location, helpfulness of staff,
Hair dryer broken, walls scuffed, room very small
Location, convenience, room was good for price! Read reviews and panicked - however we paid for deluxe rooms and they were great considering what we had paid especially on NYE! Staff were friendly and helpful and we had everything we needed. In London if you want and expect 5* then you would need to prepared to pay for it!! This however was a pleasant little place but if you don't pay mega bucks don't expect the ritz! We had room 24 & 40...
Surroundings ie hallways and reception were scruffy. Don't know what other rooms were like but Deluxe rooms were ok.
Location was excellent
Tv didn't work, kitchen was in a cupboard, room was tiny, bathroom door didn't ckose properly, shower stuck facing the wall
Nothing. At all.
Room is tiny. Fridge opens about 6 inches before hitting bed. Barely enough space to get past the bed to other end of room. No space for luggage. Shower only has hot water in afternoon. All taps spray everywhere when used. "Kitchenette" too small to be of use. Thinnest curtains in the world - streetlight right outside room makes it almost impossible to sleep. No tea/coffee, and despite kitchette, no means to wash your own dishes and house keeping doesnt do them either
It is very convenient as it was close to the thbe station
It was very dirty, dusty, rubbish from other customers under the bed, even magazines! So we won't back unfortunately. Also the kitchenette did not work, so we couldn't cook everyday as we planned :(
The location from the tube was brilliant. Staff were friendly and helpful. Fresh towels daily.
Room on booking.com, said double studio, it was more like a spare box room. No iron, hair dryer was broken and missing parts. There was hangers but on hooks, hanging space or cupboard.
I would like to see more hotrls like Dylan Appartments good all the way.
Wifi too slow
The apartment is located super near to the underground, and the front desk staff were nice
They didn't bother to clean the apartment or change the toilet paper, after 6 days staying there it was really annoying to ask for new paper every time and see the floor getting all dirty.
We found 4 different color's hair on the bed sheet and pillow cover which are not belong to us on the first day we stay.
The location. Staff. And value of money
The bed wasn't very comfy
It was close to the tube station
The room was little, - it is more bedsit and less studio apartment, they are stingy with the shower gel (I got one measly sachet for a 5 night stay), the room was not well cleaned, the sheets were not changed, there were inadequate kitchen utensils, the heater did not do much to dispel the cold, the duvet was thin (about 4.5 tog). All in all, it was nothing like the photos and I would not recommend it to anyone!
customer servive was poor the place is suppose to be a studio but no cooking utensils TV was not working Toilet was not clean before i checked in. No phone in the room, I have to go down each time I needed to speak to someone. Lack basic facilities compare to what is obtainable for the same price in the same environment. My trip was messed up
The only thing that can be rated as a positive is its proximity to the Earl's court tube station
Extremely disappointing experience! The rooms were unkept, extremely small, forget a small wardrobe there was not even a single hangar for clothes, no dustbin in the room, no tissue rolls in the toilet, Wifi never worked even for once, staff were unfriendly except for one staff member named Sunny who was very helpful. I would NOT recommend this "hotel" to anyone and I am definitely not coming to this place again!
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Sensex 29182.95 -498.82 -1.68%
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PayMate, India's leading mobile payments company, has successfully launched an innovative application for mobile fund transfers that is now powering the Inter Bank Mobile Payment Service (IMPS) of three leading banks in the country. Currently live at Syndicate Bank, Lakshmi Vilas Bank and South Indian Bank, PayMate's application is a shot in the arm to Inter Bank Mobile Payment Services in the country.
The IMPS facility was launched with much fanfare in November 2010, under the aegis of the National Payment Corporation of India (NPCI). It promised an instant interbank electronic fund transfer service that customers could conveniently access using their mobile phones. However, although the facility is being offered by over 20 banks across the country, the adoption rate has been low. Industry analysts have attributed this to the fact that the service in its present format is custom-made for smartphone users who can download an application from their respective banks and use it to make a fund transfer. Users with basic phones have the option of transferring funds via an SMS which limits the transaction value. PayMate's IMPS application add to these two modes of funds transfer with a third option that is a hybrid SMS-IVR based solution that allows even a basic phone user to transfer funds up to Rs 50,000/-. With PayMate powering IMPS services of 3 banks and with at least 5 additional banks in the pre-launch phase, PayMate is the single largest technology solution provider to banks for IMPS.
Commenting on the launch of the application, Ajay Adiseshann, Founder and Managing Director, PayMate says, "Being a leader and an innovator in the mobile payments space, new opportunities always excite us. IMPS services would be another such service we would like to exploit and which layers over the foundation we have already laid over the last 5 years."
P.R. Somasundaram, CEO and MD of Lakshmi Vilas Bank said: "We have partnered with Paymate for the mobile application. We will be ahead of the queue in launching such technology driven payment solutions. We believe that such transaction platforms will define banking services more so as we focus on financial inclusion as a key business opportunity."
A spokesperson from Syndicate Bank, commenting on the service, said "This innovative solution from Paymate will allow customers to use their mobile for transactions anytime, anywhere."
Currently, the Reserve Bank of India has allowed 39 banks to launch mobile banking services and recently raised the limit for the amount which can be paid through mobile phones to Rs 50,000. As per the latest report released by Telecom Regulatory Authoority of India (TRAI), India has 538.38 million urban subscribers while 267.74 million rural subscribers. With just 19-20% of urban subscribers using smartphones, there is an urgent need to reach out to other subscribers and enable them to use IMPS and PayMate's application will put IMPS within the reach of millions.
India Infoline News Service / 09:04, Jan 22, 2015
The outlook is a flat start. The market will look to scale to new peaks though not much effort is needed for the same. HUL saw a rally and short-covering may have pulled it up further. Speculation is on that its parent will raise stake through an open offer. After the cooling in oil prices, Cairn results will be in focus.


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1022 results for "espn los angeles"
Melo, Jeanie Buss to meet? Awkward
Ian BegleyThings may get awkward between Phil Jackson and his fiancee, Jeanie Buss, on Thursday. Buss' Los Angeles Lakers are meeting with Carmelo Anthony and his representatives in Los Angeles on Thursday, and according to ESPN Los Angeles' Dave McMenamin...
Blog | July 03, 2014 -
SVP and Russillo on ESPN Radio: Show Preview July 3, 2014
Thursday, Jorge Sedano hosts from the Bristol, CT studios. He'll welcome United States D Matt Besler (1:15 p.m. ET), ESPN Los Angeles' Dave McMenamin (1:45), ESPN NBA analyst P.J. Carlesimo (2:15) and ESPN the Magazine and ESPN.com editor-in-chief Ch...
Blog | Conversation | July 03, 2014 -
Mike & Mike on ESPN Radio: Show Preview June 26, 2014
Greeny and Golic welcome ESPN Los Angeles' Ramona Shelburne (6:10 a.m. ET), ESPN.com NBA Insider Marc Stein (7:30), ESPN NBA draft Insider Chad Ford (8:10), Michigan coach Brady Hoke (8:30), ESPN soccer analyst Tommy Smyth (9:00) and four-time world ...
Blog | Conversation | June 25, 2014 -
Herd on ESPN Radio: Show Preview May 30, 2014
Ian O'Connor will be joined by ESPN NBA analyst Bruce Bowen (10:45 a.m. ET), former NBA G Steve Smith (11:15) and ESPN Los Angeles' Ramona Shelburne (12:00 p.m.) on Friday. As always, email the show (firstname.lastname@example.com) or tweet us at twitter.co...
Blog | Conversation | May 30, 2014 -
Bryon Scott on Max & Marcellus
ESPN Los AngelesLos Angeles Lakers head coaching candidate Byron Scott joined Max & Marcellus on Thursday afternoon. Scott says the interview with Mitch Kupchak went well and he feels like the perfect fit for the job. He also talked about the reasons he would love t...
Blog | May 23, 2014 -
NBA trade deadline: Latest chatter
Nick BorgesThe NBA trade deadline is today (Thursday) at 3 p.m. ET. Two trades went down Wednesday, and more should be completed prior to the deadline. Here is the latest scuttlebutt from around the league: From Ramona Shelburne of ESPN Los Angeles: "Sense...
Blog | February 20, 2014 -
Trade grades - Warriors get Blake
Kevin PeltonKevin Pelton gives his take on the deal that sends Steve Blake to the Warriors, and Kent Bazemore and MarShon Brooks to the Lakers.
Story | Conversation | February 19, 2014 -
Forum: Should the Lakers tank the season?
ESPN Los AngelesMark Willard and Arash Markazi debate whether the Lakers, mired in another difficult season, should tank their season in pursuit of a prime draft pick....
Blog | December 30, 2013 -
Forum: Lakers to deal Gasol?
ESPN Los AngelesWith the NBA trade deadline approaching, Mark Willard and Arash Markazi discuss the possibility of the Lakers moving Pau Gasol....
Blog | December 30, 2013 -
Chris Paul on Max & Marcellus
ESPN Los AngelesLos Angeles Clippers guard Chris Paul joined the Max & Marcellus show on Thursday on ESPNLA 710. Paul says this season is all about trying to play ball the right way. CP3 says hearing the injury news about Kobe Bryant is disheartening but he expects ...
Blog | December 19, 2013 -
Forum: Kobe Bryant's role
ESPN Los AngelesMark Willard and Dave McMenamin discuss Kobe Bryant's role when he returns from injury....
Blog | December 03, 2013 -
Forum: Pau Gasol's future in L.A.
ESPN Los AngelesMark Willard and Dave McMenamin discuss whether Pau Gasol's days are numbered with the Lakers....
Blog | December 03, 2013 -
Forum: Expectations for Kobe Bryant
ESPN Los AngelesArash Markazi and Mark Willard break down the expectations for Kobe Bryant now that he is practicing and expected to playing in games soon....
Blog | November 19, 2013 -
Forum: Hill making a name for himself
ESPN Los AngelesMark Willard and Arash Markazi break down whether the Los Angeles Lakers should include Jordan Hill in their long-term plans....
Blog | November 19, 2013 -
Mike D'Antoni joins Dan Le Batard
ESPN Los AngelesLos Angeles Lakers coach Mike D'Antoni joins Dan Le Batard, Stu Gotz and Stan Van Gundy to discuss Kobe Bryant's injury and moving on from a difficult 2012-13 season. Click here to listen to the full interview...
Blog | November 06, 2013 -
Forum: Kobe's knee worries
ESPN Los AngelesMark Willard and Arash Markazi discuss Kobe Bryant's injury concerns after he traveled to Germany to receive treatment....
Blog | October 09, 2013


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Two TSPO structures; optogenetics used to define neurons associated with thirst and overeating; transposons and the evolution of pregnancy
The European Commission unveiled a linkurl:draft protocol;http://ec.europa.eu/environment/chemicals/lab_animals/pdf/com_2008_543.pdf on animal welfare today (Nov. 5) that proposes to ban testing on great apes including gorillas, chimpanzees, bonobos, and orangutans. The pan-European initiative would extend a ban already in force in Austria, Great Britain, the Netherlands, and Sweden across the entire 27-member bloc. The ban, however, would not greatly affect current research, because no testing
November 5, 2008
|November 6, 2008
November 6, 2008


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Belfast, Mount View make pink fashionable on football field
In preparation for new football season, Lions, Mustangs tackle each otherBelfast — The Belfast and Mount View athletic programs have had a longstanding Waldo County rivalry, but, for one day each fall, the Lions and Mustangs come together to support a greater cause, a more important outcome than which one of them will win a specific sporting event.
That day, or make it night, came on Friday, Aug. 29 as the Lions and Mustangs played a high school preseason football game on Dennis "Bear" Bryant Field to raise money to support the research for a cure and the subsequent care for those afflicted with breast cancer.
While Class C Belfast dominated Class D Mount View on the field in front of a large crowd of fans for both teams, the mood also was about supporting the important health cause.
In the end, it was Belfast that came away with a 50-13 victory.
In fact, pink was fashionable for all participants, as the players wore pink socks and sweatbands, while the coaches sported pink polo shirts. Even the program for fans was printed on pink paper.
The game is held annually in either Belfast or Thorndike before the two squads begin their regular seasons.
Fullback Alex Canning had three touchdowns on the day for Belfast on two 35-yard scores and another 24-yard run, while Drew Nealey, the team's quarterback, scored on runs of 10 and 56 yards, respectively.
Steven Davis, who played his first three years with Mount View but transferred to Belfast for his senior season, added a 48-yard touchdown run, while Marlin Hansen added a 36-yard interception return for a touchdown.
Tyler Ripley and Gavin Simpson had touchdown runs of three and five yards, respectively, for Mount View.
For the upcoming season, Belfast has nearly 50 players and is expected to be one of the league's strongest teams. Mount View has a smaller group, with about half as many student-athletes as the Lions.
Click for photos from the Mount View and Belfast game. See photos and video below.
Staff Profile
Ken Waltz has been member of the media 30 years and has received hundreds of Maine Press Association and New England Press Association awards for his writing, photography and page design. He studied journalism at the University of Maine in Orono. He lives in South Thomaston with his wife, Sarah. The couple has an adult son, Brandon.
Recent Stories by Ken Waltz
Some Midcoast court games pushed ahead to Jan. 26
Jan 26, 2015 -
Defense, accurate shooting, balanced scoring winning ticket for Searsport
Jan 18, 2015 -
Oceanside stays step ahead of Belfast in fast-paced affair
Jan 16, 2015 -
Mount View gallops away from Belfast to make convincing court case
Jan 07, 2015 -
As Patriot fans, be afraid — very afraid
Jan 04, 2015


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Publications (38)181.32 Total impact
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ABSTRACT: Site-specific degeneration patterns of the infratentorial brain in relation to phylogenetic origins may relate to symptoms in patients with spinocerebellar degeneration, but the patterns are still unclear. We investigated macro- and microstructural changes of the infratentorial brain based on phylogenetic origins and their correlation with symptoms in patients with spinocerebellar ataxia type 6.American Journal of Neuroradiology 08/2014; · 3.68 Impact Factor - Neurotoxicology and Teratology 05/2012; 34(3):376. · 3.22 Impact Factor
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ABSTRACT: Strong genetic evidence implicates mutations and polymorphisms in the gene Disrupted-In-Schizophrenia-1 (DISC1) as risk factors for both schizophrenia and mood disorders. Recent studies have shown that DISC1 has important functions in both brain development and adult brain function. We have described earlier a transgenic mouse model of inducible expression of mutant human DISC1 (hDISC1) that acts in a dominant-negative manner to induce the marked neurobehavioral abnormalities. To gain insight into the roles of DISC1 at various stages of neurodevelopment, we examined the effects of mutant hDISC1 expressed during (1) only prenatal period, (2) only postnatal period, or (3) both periods. All periods of expression similarly led to decreased levels of cortical dopamine (DA) and fewer parvalbumin-positive neurons in the cortex. Combined prenatal and postnatal expression produced increased aggression and enhanced response to psychostimulants in male mice along with increased linear density of dendritic spines on neurons of the dentate gyrus of the hippocampus, and lower levels of endogenous DISC1 and LIS1. Prenatal expression only resulted in smaller brain volume, whereas selective postnatal expression gave rise to decreased social behavior in male mice and depression-like responses in female mice as well as enlarged lateral ventricles and decreased DA content in the hippocampus of female mice, and decreased level of endogenous DISC1. Our data show that mutant hDISC1 exerts differential effects on neurobehavioral phenotypes, depending on the stage of development at which the protein is expressed. The multiple and diverse abnormalities detected in mutant DISC1 mice are reminiscent of findings in major mental diseases.Molecular Psychiatry 03/2011; 16(3):293-306. · 15.15 Impact Factor -
Article: White matter impairment in Rett syndrome: diffusion tensor imaging study with clinical correlations.
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ABSTRACT: RTT, caused by mutations in the methyl CPG binding protein 2 (MeCP2) gene, is a disorder of neuronal maturation and connections. Our aim was to prospectively examine FA by DTI and correlate this with certain clinical features in patients with RTT. Thirty-two patients with RTT underwent neurologic assessments and DTI. Thirty-seven age-matched healthy female control subjects were studied for comparison. With use of a 1.5T MR imaging unit, DTI data were acquired, and FA was evaluated to investigate multiple regional tract-specific abnormalities in patients with RTT. In RTT, significant reductions in FA were noted in the genu and splenium of the corpus callosum and external capsule, with regions of significant reductions in the cingulate, internal capsule, posterior thalamic radiation, and frontal white matter. In contrast, FA of visual pathways was similar to control subjects. FA in the superior longitudinal fasciculus, which is associated with speech, was equal to control subjects in patients with preserved speech (phrases and sentences) (P = .542), whereas FA was reduced in those patients who were nonverbal or speaking only single words (P < .001). No correlations between FA values for tracts and clinical features such as seizures, gross or fine motor skills, and head circumference were identified. DTI, a noninvasive technique to assess white matter tract pathologic features, may add specificity to the assessment of RTT clinical severity that is presently based on the classification of MeCP2 gene mutation and X-inactivation.American Journal of Neuroradiology 10/2009; 31(2):295-9. · 3.17 Impact Factor - NeuroImage 07/2009; 47. · 6.13 Impact Factor
Article: Improved Segmentation of Hippocampus Using Landmark based Large Deformation Diffeomorphic Mapping
NeuroImage 07/2009; 47. · 6.13 Impact Factor - NeuroImage 07/2009; 47. · 6.13 Impact Factor
- NeuroImage 07/2009; 47:S123. · 6.13 Impact Factor
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ABSTRACT: Stereotaxic atlases of the mouse brain are important in neuroscience research for targeting of specific internal brain structures during surgical operations. The effectiveness of stereotaxic surgery depends on accurate mapping of the brain structures relative to landmarks on the skull. During postnatal development in the mouse, rapid growth-related changes in the brain occur concurrently with growth of bony plates at the cranial sutures, therefore adult mouse brain atlases cannot be used to precisely guide stereotaxis in developing brains. In this study, three-dimensional stereotaxic atlases of C57BL/6J mouse brains at six postnatal developmental stages: postnatal day (P) 7, P14, P21, P28, P63 and in adults (P140-P160) were developed, using diffusion tensor imaging (DTI) and micro-computed tomography (CT). At present, most widely-used stereotaxic atlases of the mouse brain are based on histology, but the anatomical fidelity of ex vivo atlases to in vivo mouse brains has not been evaluated previously. To account for ex vivo tissue distortion due to fixation as well as individual variability in the brain, we developed a population-averaged in vivo magnetic resonance imaging adult mouse brain stereotaxic atlas, and a distortion-corrected DTI atlas was generated by nonlinearly warping ex vivo data to the population-averaged in vivo atlas. These atlas resources were developed and made available through a new software user-interface with the objective of improving the accuracy of targeting brain structures during stereotaxic surgery in developing and adult C57BL/6J mouse brains.Neuroscience 06/2009; 162(4):1339-50. · 3.33 Impact Factor - International Journal of Radiation OncologyBiologyPhysics 09/2008; 72(1). · 4.18 Impact Factor
- Molecular Psychiatry 03/2008; 13(2):115. · 15.15 Impact Factor
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ABSTRACT: A strong candidate gene for schizophrenia and major mental disorders, disrupted-in-schizophrenia 1 (DISC1) was first described in a large Scottish family in which a balanced chromosomal translocation segregates with schizophrenia and other psychiatric illnesses. The translocation mutation may result in loss of DISC1 function via haploinsufficiency or dominant-negative effects of a predicted mutant DISC1 truncated protein product. DISC1 has been implicated in neurodevelopment, including maturation of the cerebral cortex. To evaluate the neuronal and behavioral effects of mutant DISC1, the Tet-off system under the regulation of the CAMKII promoter was used to generate transgenic mice with inducible expression of mutant human DISC1 (hDISC1) limited to forebrain regions, including cerebral cortex, hippocampus and striatum. Expression of mutant hDISC1 was not associated with gross neurodevelopmental abnormalities, but led to a mild enlargement of the lateral ventricles and attenuation of neurite outgrowth in primary cortical neurons. These morphological changes were associated with decreased protein levels of endogenous mouse DISC1, LIS1 and SNAP-25. Compared to their sex-matched littermate controls, mutant hDISC1 transgenic male mice exhibited spontaneous hyperactivity in the open field and alterations in social interaction, and transgenic female mice showed deficient spatial memory. The results show that the neuronal and behavioral effects of mutant hDISC1 are consistent with a dominant-negative mechanism, and are similar to some features of schizophrenia. The present mouse model may facilitate the study of aspects of the pathogenesis of schizophrenia.Molecular Psychiatry 03/2008; 13(2):173-86, 115. · 15.15 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Conventional MR imaging shows evidence of brain injury and/or maldevelopment in 70%-90% of children with cerebral palsy (CP), though its capability to identify specific white matter tract injury is limited. The great variability of white matter lesions in CP already demonstrated by postmortem studies is thought to be one of the reasons why response to treatment is so variable. Our hypothesis is that diffusion tensor imaging (DTI) is a suitable technique to provide in vivo characterization of specific white matter tract lesions in children with CP associated with periventricular leukomalacia (PVL). In this study, 24 children with CP associated with PVL and 35 healthy controls were evaluated with DTI. Criteria for identification of 26 white matter tracts on the basis of 2D DTI color-coded maps were established, and a qualitative scoring system, based on visual inspection of the tracts in comparison with age-matched controls, was used to grade the severity of abnormalities. An ordinal grading system (0=normal, 1=abnormal, 2=severely abnormal or absent) was used to score each white matter tract. There was marked variability in white matter injury pattern in patients with PVL, with the most frequent injury to the retrolenticular part of the internal capsule, posterior thalamic radiation, superior corona radiata, and commissural fibers. DTI is a suitable technique for in vivo assessment of specific white matter lesions in patients with PVL and, thus, a potentially valuable diagnostic tool. The tract-specific evaluation revealed a family of tracts that are highly susceptible in PVL, important information that can potentially be used to tailor treatment options in the future.American Journal of Neuroradiology 09/2007; 28(7):1213-22. · 3.68 Impact Factor -
Article: SENSE-DTI at 3 T.
[Show abstract] [Hide abstract]
ABSTRACT: While holding vast potential, diffusion tensor imaging (DTI) with single-excitation protocols still faces serious challenges. Limited spatial resolution, susceptibility to magnetic field inhomogeneity, and low signal-to-noise ratio (SNR) may be considered the most prominent limitations. It is demonstrated that all of these shortcomings can be effectively mitigated by the transition to parallel imaging technology and high magnetic field strength. Using the sensitivity encoding (SENSE) technique at 3 T, brain DTI was performed in nine healthy volunteers. Despite enhanced field inhomogeneity, parallel acquisition permitted both controlling geometric distortions and enhancing spatial resolution up to 0.8 mm in-plane. Heightened SNR requirements were met in part by high base sensitivity at 3 T. A further significant increase in SNR efficiency was accomplished by SENSE acquisition, exploiting enhanced encoding speed for echo time reduction. Based on the resulting image data, high-resolution tensor mapping is demonstrated.Magnetic Resonance in Medicine 03/2004; 51(2):230-6. · 3.40 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: The authors used diffusion-tensor imaging to examine central white matter pathways in two children with spastic quadriplegic cerebral palsy. Corticospinal tracts projecting from cortex to brainstem resembled controls. In contrast, posterior regions of the corpus callosum, internal capsule, and corona radiata were markedly reduced, primarily in white matter fibers connected to sensory cortex. These findings suggest that the motor impairment in periventricular leukomalacia may, in part, reflect disruption of sensory connections outside classic pyramidal motor pathways.Neurology 10/2002; 59(5):752-6. · 8.30 Impact Factor - AJR Am J Roentgenol. 01/2002; 178:3–16.
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ABSTRACT: Neuroimaging is a key instrument for determining structural and in vivo functional status of the brain, non-invasively. Multiple approaches can now determine aspects of anatomic and neurochemical changes in brain, and have been utilized effectively in Rett Syndrome patients to understand the biological basis of this neurodevelopmental disorder. Studies performed at our institute include volumetric analyses of MRI, magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI), cerebral blood flow measurements with MRI, and positron emission tomography scans (PET). These studies have provided considerable insight into mechanisms underlying the clinical features of this disease. Volumetric analyses suggest that decreased brain volume in RS results from global reductions in both gray and white matter of the brain. A selective vulnerability of the frontal lobes is evidenced by the preferential reduction of blood flow, increased choline and reduced n-acetyl aspartate (NAA) by MRS, and increased glucose uptake in these same regions as shown by ((18)F)-fluorodeoxyglucose (FDG) PET scans. We hypothesize that the increased glucose uptake relates to increased glutamate cycling in synapses. The resulting neuroexcitotoxic injury to the developing brain contributes to the seizures, behavioral disturbance and respiratory irregularities commonly seen in phases 1 and 2 of this disorder.Brain and Development 01/2002; 23 Suppl 1:S62-71. · 1.54 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: It is shown that diffusion tensor MR imaging (DTI) can discretely delineate the microstructure of white matter and gray matter in embryonic and early postnatal mouse brains based on the existence and orientation of ordered structures. This order was found not only in white matter but also in the cortical plate and the periventricular zone, which are precursors of the cerebral cortex. This DTI-based information could be used to accomplish the automated spatial definition of the cortical plate and various axonal tracts. The DTI studies also revealed a characteristic evolution of diffusion anisotropy in the cortex of the developing brain. This ability to detect changes in the organization of the brain during development will greatly enhance morphological studies of transgenic and knockout models of cortical dysfunction. Magn Reson Med 46:18-23, 2001.Magnetic Resonance in Medicine 08/2001; 46(1):18-23. · 3.40 Impact Factor - [Show abstract] [Hide abstract]
ABSTRACT: Brain diffusion tensor MRI of 11 boys with X-linked adrenoleukodystrophy was performed. The authors determined quantitative isotropic apparent diffusion coefficient (ADC(i)) and fractional anisotropy (FA) values in the white matter. ADC(i) and FA values in the affected white matter were significantly different from those in normal-appearing white matter. Zonal ADC(i) and FA gradations, which might originate from well-established histopathologic zonal changes, existed within affected white matter.Neurology 03/2001; 56(4):544-7. · 8.30 Impact Factor -
Article: 328. Differences in white matter connectivity in men and women with and without schizophrenia
Biological Psychiatry 04/2000; 47(8). · 9.47 Impact Factor
Publication Stats
2k | Citations | |
181.32 | Total Impact Points | |
Top Journals
Johns Hopkins University
- • Department of Radiology
- • Department of Biophysics and Biophysical Chemistry
Baltimore, Maryland, United States
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
San Paulo, São Paulo, Brazil
Kennedy Krieger Institute
Baltimore, Maryland, United States


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