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Mathers inducted into motorcycle hall of fame
Published: Tuesday, December 8, 2009 at 4:30 a.m.
Last Modified: Monday, December 7, 2009 at 8:08 p.m.
Hendersonville resident Gary Mathers was among nine individuals inducted into the American Motorcyclist Association Motorcycle Hall of Fame Saturday in a gala ceremony at the Hard Rock Hotel and Casino Las Vegas.
The event was hosted by Hollywood actor and avid motorcyclist Perry King, and was attended by hundreds of motorcycling enthusiasts from across the country.
Mathers is well-known as a highly successful motorcycle race team manager. During his career, he produced dozens of championships in road racing, dirt track, Supercross and motocross for Honda and Kawasaki. His keen eye for talent discovered future Grand Prix World Champion roadracers Eddie Lawson and Wayne Rainey while he was with Kawasaki.
In addition, Mathers' teams took a total of 48 championships in dirt-track, motocross, Supercross and roadracing, winning two championships in all but one of his 16 years at American Honda.
"I rode dirtbikes as a kid. I had a Harley-Davidson two-stroker dirtbike. I was doing some cross country," Mathers recounted of his introduction to motorcycling for American Motorcyclist magazine, which featured the Hall of Fame inductees in its December issue. "About two years after I graduated from high school, I converted a BSA into a dirt-tracker. I was sponsored by Tribers Cycle out of Spokane, Wash., and when the owner opened a new store, I ended up managing it for him."
He also told the magazine that he found his best racers on the dirt track, because these kids, "By the time they're 21, they probably have 200, even 400, races under their belt. A pure road racer might have 30 or 40. The dirt trackers are used to going 110 miles sideways on a mile, so getting on a road bike was nothing to them."
During the induction ceremony, AMA President and CEO Rob Dingman presented Mathers with an engraved AMA Hall of Fame ring.
The AMA Hall of Fame is located on the AMA campus in Pickerington, Ohio, and recognizes men and women who have made significant contributions to American motorcycling. Among its past inductees are Steve McQueen, Malcolm Forbes, Evel Knievel and Jay Leno.
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Rocksmith 2014 Trailer Shows 'Guitarcade' Mini-Games
Written Tuesday, September 24, 2013 By Richard WalkerView author's profile
Ubisoft has released rockin' new Rocksmith 2014 trailer today, showing off the game's new 'Guitarcade' mini-games that have been designed to hone specific guitar skills, with leaderboards thrown in for good measure.
Presented by Technical Art Project Lead Aaron Murray, the vid shows you games like 'Ducks Redux', 'Scale Racer' and 'Gone Wailin' ', which aim to teach basics like moving up and down the fret board, playing the scales and playing loudly and softly.
There's also the 'Return to Castle Chordead' in which you zap zombies while playing certain chords. You'll be shredding your axe like a pro in no time. Rock on and stuff. Rocksmith 2014 is out this October.

subset: commoncrawl


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Tag Archives: domestic violence
Task force hosts community conversation on domestic violence
Community training has a domestic violence focus
Sitkans Against Family Violence will begin their free community training this Saturday, August 22. According to SAFV's Martina Kurzer, this year's training will include sessions on trauma and self-care, how domestic violence affects children, and legal advocacy. The annual training is open to Sitkans who want to become an ally for all those who suffer secretly from interpersonal violence. Downloadable audio.
Domestic violence: How to hold perpetrators accountable?
Assistant District Attorney Jean Seaton and paralegal Elisabeth Schafer talk about how criminal process serves victims and perpetrators of domestic violence. October is Domestic Violence Awareness Month.
March for R-E-S-P-E-C-T
Students from Mt. Edgecumbe and Sitka High Schools joined community members, Sitka's domestic violence task force, and a contingent of State Troopers, among others, as they marched through downtown on Thursday (3-27-14), as part of the 5th annual "Choose Respect" rally to raise awareness of domestic violence.


text: '''Airdate:''' January 31, 2010[[quoteright:320:http://static.tvtropes.org/pmwiki/pub/images/ckfepovf_5027.png]][[caption-width-right:320:"Hands in the air, Goldman!"]] Brian gets a job writing for a teen magazine -- and finds his first story when Meg begins bonding with an escaped prisoner. And when Meg gets busted for harboring said escaped convict, she ends up in prison and is released later as a hardened thug.----!!"Dial Meg For Murder." contains examples of ([[YMMV/FamilyGuyS8E11DialMegForMurder YMMV goes here]]):* AssShove: Meg does this to Peter with a loofah.* BewareTheNiceOnes[=/=]FromNobodyToNightmare: Good lord, '''Meg'''. She completely flips out after coming out of prison.* BlackComedyRape: Peter is a victim of this twice (possibly a series record):** It is implied that a bull -- a 1,000 male steer -- rapes Peter. Never mind the sheer ridiculousness of this (humans romancing [[WesternAnimation/BugsBunny animals they think are people]] have dated to the beginnings of Western Animation), but if a steer were actually able to sexually assault a human being, the man would surely be killed, if not severely sickened and violently injured. (Not to mention that the bull would probably have been shot and killed if he began doing this in a public arena.)** Peter suffers more of this later in the episode, when Meg returns home from prison and sexually assaults him repeatedly, first by interrupting his shower.* BullyingADragon: Connie and her friends making fun of Meg after she returns to school from prison. They pay for it, big time.* CurbStompBattle: Meg dishes these out to every one. She even gives Peter a literal curb stomp (or in this case, "stair stomp").* TheDogBitesBack: This episode is basically Meg getting pushed beyond the brink and getting revenge on those who bullied her (including her own parents).* HadToComeToPrisonToBeACrook: This episode even provides one half of the page image.* {{Jerkass}}: Peter, Connie and her friends to Meg, which is why she gives them the beat-down they deserve.* KickTheSonOfABitch: The punishment that Peter and the popular kids receive by Meg.* LaserGuidedKarma: Peter and the popular kids suffer this after tormenting Meg. And Lois all but getting the same treatment after refusing to hear her out earlier regarding the story she gave about the inmate and forbidding her from seeing him again, which led to Lois' current predicament in the first place.* NoHoldsBarredBeatdown: See CurbStompBattle.* NoSympathy: Lois does not care one bit about Meg's story and forbids her from seeing the inmate again. Granted the guy ''is'' a criminal and they can be dangerous, but the fact that he's gentle around Meg should say ''something''.* OnlySaneMan: Brian (well in this episode).* ParentalHypocrisy: Lois telling off Meg for dating a convict doesn't seem so in-place when you remember that she was once arrested for shoplifting. Same goes for Peter, who has been arrested far more times than Lois.* PetTheDog: Brian telling Meg that she is "far sweeter and kinder than the typical American girl."* PrisonRape: Presumably what happened to Meg in prison, and hence her current demeanor.* RecursiveCanon: Peter finds out the plot of the episode by reading it from TV Guide.* RoaringRampageOfRevenge: Meg whacking the popular kids in retaliation.* TheStoolPigeon: Brian. Justified in that he's shown to actually be concerned for Meg's safety rather than wanting to get her in hot water. Meg, however, doesn't appreciate this one bit.* TakeThat: After Peter's final line about Meg's overly esoteric reference "Always end on a strong joke." The credits and theme are very reminiscent of [[TheSimpsons another animated comedy series]].* TakeThatKiss: Meg French kisses Connie after knocking her out cold.* TranquilFury: Meg's default mood after coming out of prison.* TemporarilyAVillain: Meg. Justified in-story as she went to prison and had to fight for survival, and justified in the fandom as revenge to all the people who have treated her like crap throughout the series.* TooDumbToLive and WhatAnIdiot: Brian. While he tries to talk Meg out or robbing Mort's pharmacy, it doesn't occur to him that trying to reason with her with words would get him killed.** Connie and her friends. Did they not notice or care that Meg's time in prison would make her violent? Apparently not, because they ''still'' make fun of her before having their asses handed to them.** Peter. Chris even lampshades this: "Dad, show some humility, it'll save your life!"* TookALevelInBadass[=/=]WhosLaughingNow: Meg. Just see above.* WhatHappenedToTheMouse: After Meg is arrested, Luke is never seen or mentioned again until the end of the episode, while Brian is talking Meg down from robbing Mort.* WoobieDestroyerOfWorlds: At the end of the episode, Meg attempts to rob Mort's pharmacy and is one police call away from falling even deeper right before Brian defuses the situation by reading her the article he wrote about her.


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ResveraPrime® Advantage (30 capsules, 1-month supply)
Item## MRE
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Video Industry News Video Company News Technology Industry News Technology Company News Novelty Industry News Novelty Company News Gay Industry News Gay Company News Legal Industry News All Company News
Released: Feb 01st, 1997
Running Time: 80
Director: Damion Roberts
Company: Unlimited Productions
Cast: Tommy Gunn, Ian Daniels, Peyton Alexander, Dallas (I), Rick Masters, Dick Nasty, Sweetie Pie
Critical Rating: AA
Genre: Feature
Everyone sits around whining about relationships, but thankfully the audio barely captures any of this nonsense. Still, we've got to deal with the picture at hand. Tommy Gunn shoots Sweetie Pie in the ass in the best sequence, which barely covers the action. Peyton plays grab-ass with Dallas and has a tryst with Dick Nasty and Rick Masters, but it would be kinder to shut up already.


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Teaching Large Classes
Doing it well.
By following the links to any of the sites listed within this page, you will exit the OFFICIAL UCO WEBSITE and be directed to the respective resource which is not a part of the www.uco.edu domain.
- Teaching Large Classes in the STEM Disciplines
- Survival Handbook for Teaching Large Classes from UNCC
- Richard Felder Paper on Teaching Large Classes Effectively (Felder is a long-time researcher/practitioner in college teaching)
- Univ of Maryland Teaching Guide for Large Classes
- Teaching Technologies for Large Classes
To view the hardcopy resources available in the CETTL Library on teaching large classes, click here.


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Currently browsing "Information Storage"
Memory Athletes and Researchers Collaborate to Dissect Feats of Memory
Competitors at the 2nd Annual Extreme Memory Tournament tested their mettle with feats of memorization and recall while working with researchers studying how memory works. ... More>
Gazzaniga Receives APS Lifetime Achievement Award
APS Past President Michael S. Gazzaniga has been named a 2015 William James Fellow Award recipient for lifetime contributions to basic psychological science for his innovative experiments with split-brain patients, […]... More>
Observer Article
Mining the Unconscious
Scientists dig into the submerged layer of cognitive function. ... More>
Observer Article
PSPI Reports: Effective Study Techniques, Power of Misinformation
Elizabeth J. Marsh of Duke University, and Stephan Lewandowsky of the University of Western Australia and Bristol University in the United Kingdom, present the findings from their respective papers at the fifth annual Psychological Science in the Public Interest (PSPI) Symposium ... More>
Photographs and the Misinformation Effect: A Boundary Condition of Truthiness
Photographs have been shown to increase "truthiness" across several domains. This study explores the presentation of nonprobative photographs in a misinformation study. ... More>


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- Fundraise
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- Finding Prevention & a Cure
Donna S. Hall Chair in Breast Cancer Research
American Cancer Society Clinical Research Professor
Professor of Medicine and Cancer Biology
Director, Breast Cancer Research Program Vanderbilt-Ingram Cancer Center (VICC)
Associate Director for Clinical Research at VICC
Vanderbilt University Medical Center
Nashville, Tennessee
Most estrogen receptor-positive (ER+) breast cancers depend on female hormones and initially respond to anti-estrogen (endocrine) therapies, such as tamoxifen, aromatase inhibitors and fulvestrant. However, many of these cancers eventually become resistant to ER-targeted therapies. Dr. Arteaga's BCRF research is focused on understanding why ER+ tumors become resistant and developing new approaches to improve clinical outcomes. His group is conducting a clinical trial where women with ER+ breast cancer receive the aromatase inhibitor letrozole for 10-21 days prior to surgery (neoadjuvant therapy) to discover mechanisms of resistance to anti-estrogen therapy. Using a molecular marker of cell growth called Ki67, they distinguish between tumors that are responsive to the therapy (low Ki67) versus those that are not and continue to grow (high Ki67). Coupling this data with genetic profiling, they have identified the gene FGFR1 as a potential therapeutic target to prevent endocrine resistance. Parallel to these studies, they are conducting clinical trials with FGFR inhibitors in patients with breast cancers that have high levels of the FGFR1 gene. Early results are promising and they are now initiating studies to combine letrozole with FGFR inhibitors in patients with this type of tumor. These studies have important clinical implications for patients with ER+ breast cancer.
Dr. Arteaga trained in Internal Medicine and Medical Oncology at Emory University and the UT Health Sciences Center San Antonio, respectively. He joined Vanderbilt in 1989 where he now holds the Donna S. Hall Chair in Breast Cancer Research and serves as Professor of Medicine and Cancer Biology. Dr. Arteaga is also Associate Director for Clinical Research, Director of the Breast Cancer Program, and Director of the Center for Cancer Targeted Therapies at the Vanderbilt-Ingram Cancer Center. He has over 250 publications in the areas of signaling by growth factor receptors and oncogenes, targeted therapies and biomarkers of drug resistance, and investigator-initiated clinical trials in breast cancer. Since 2002, he has directed the NCI-funded Vanderbilt Breast SPORE. He is a member of the ASCI and the Association of American Physicians. He received the AACR Richard & Hinda Rosenthal Award, a 2007-2017 ACS Clinical Research Professor Award, the 2009 Gianni Bonadonna Award from ASCO and the 2011 Brinker Award from the Susan G. Komen Foundation. He has served as AACR co-chair of the annual San Antonio Breast Cancer Symposium since 2009. He is Deputy Editor of Clinical Cancer Research and member of the Editorial Board of Cancer Cell and six other peer-reviewed journals. He is immediate past President of the AACR in 2015.


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Photo Details
Sande Riggs Could this be John and Sarah(?) Riggs about 1876?
Dec 16, 2003 · Reply
Sande Riggs After talking with my father, he says these Riggs' have our family resemblence, and although he is not positive, he thinks it could possibly be his great grandparents, John and Sarah(?) Riggs holding his grandfather Noah.
Dec 28, 2003 · Reply
Joyce Skelton This is a photo of William Whitehead, Florence Beatty Whitehead and their oldest daughter Esther Lee Whitehead. They were from Wayne/Lawrence County area of Tennessee. William's uncle was married to a Riggs descendant. Joce T.
Apr 06, 2005 · Reply
Tina Warren These are my great grandparents. My father has the same photo. WILLIAM WARREN/ELIZABETH PITTS and BABY MARTHA WARREN.They lived in Decatur county and also Perry and Wayne county.
May 20, 2010 · Reply


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Monday I had gone to the ER for dark brown discharge (2 pads) and light pink discharge accompanied with cramping and off/on sharp pains. My Hcg level was 80. The Dr came in and told me I hadĀa miscarriage, I was devestated and crying. He tried consoling me and stuff but I was just so upset.
I had to go back today for another hcg level and it is 318 today and I go see the OB Dr tomorrow morning at 1130. I am having bright red bleeding now.
SOMEONE PLEASE TELL ME YOUR LEVELS AND STUFF. I am driving myself crazy. I dont understand how a Dr can come in and tell me I had a miscarriage with out an ultrasound or vaginal exam.


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'Sydney' now adorned with the beautiful Oneworld colour scheme seen here on approach into Changi as QF51 from Brisbane.
The highlight of the trip landing on 24R named for Sydney. [1600px]
Qantas 747-400ER VH-OEF in Singapore Changi Airport. It is unusual to see a 744ER here in Singapore, much less one with the special oneworld livery! Qantas usually sends the regular 744s to SIN.
A few short moments of sunlight shine down on the OneWorld Qantas 747 as she arrives non-stop from Santiago as QF28. Big scattered storms throughout that day made waiting around wort... (more)
Qantas 27 taxies out to RWY16R, beginning the long flight to Santiago.
A special thanks goes to our LAX expert for showing us around - and to fellow JP photographer Abram Chan for all the driving!
After seeing so many great shots from fellow JP photographers from this spot, I am here to try it out for myself!
QF6163 Taxiing to the bay on a glorious afternoon in Adelaide. It is not that often we see B747's Adelaide, this one was a nice suprise. This aircraft was used to operae a scenic flight over Antar... (more)
About to touch down on Runway 23 as QF6163 from Sydney, on a positioning flight in readiness to operate QF2905 scenic flight over Antarctica the following day.


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I'm so confused. We haven't introduced any new foods. We tried Tylenol & hylands teething tablets. He's not hungry. His nose mostly clear. (A little stuffy, but nothing he hasn't slept through before.)
He screams for 10 seconds then passes back out. Then two minutes later same thing. By the third time, even though he's still going back to sleep I get him out of his crib & cuddle. Nothing seems off except his swallow/saliva sounds thick.
Anyone else? What did you do?


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9 Ways to Increase Your E-Commerce Site Revenue
By Zach Hanlon-Oracle on Sep 29, 2015
My kids love when I tell them stories at bed time. Thankfully they don't mind that I'm not that creative. I end up telling versions of the same stories over and over again. More specifically I retell bits and pieces of stories from larger narratives. The Chronicles of Narnia is the go-to in my house, and the details are critically important. Every now and again I need to go back and re-read those books because I realize my renditions of them aren't having the effect they once did.
In a similar way, many of our customers get in the daily groove of selling their wares online and their growth starts to plateau. Promotions don't have the effect they once had or product category revenues start to decline. You could call it a form of complacency but it's more likely just the effects of managing complex businesses with limited resources. Occasionally as e-commerce professionals we need to be reminded a few basic principles to help maximize conversion and increase average order value. Here are 9 tips that will hopefully reinvigorate your sales and give them the jolt they might need.
1. Up-Sell vs. Cross-Sell
We have a wealth of tools and strategies to employ as commerce professionals and I'm the kind of guy that will use all the tools at my disposal to accomplish my goals, but sometime less is more. We don't cross-sell and up-sell at the same time. They distract and detract from each other.
Let's say a customer comes to my site looking for a generic category, say "drills". Because he used a generic search term, he is probably not a brand shopper. That might means he will only be persuaded to buy the drill that best fits his needs or perhaps has the most appeal. My goal would be to use product descriptions, enhanced product details, promotional pricing or rich media to get him to buy the slightly more expensive product.
On the other hand, if those same customers come to my site looking for "Dewalt Drills" then I know they already have brand preferences. I could try and up-sell them to the highest model Dewalt Drill, but I'd probably fare better letting him pick his own preference and cross-selling them some Dewalt branded accessories.
Bottom line: up-sell customers who browse categories and cross-sell customers focused on specific products.


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Bring them home, for Afghans' future and ours
As the world awaits President Obama's announcement about withdrawing U.S. troops from Afghanistan, an intense debate is taking place within the administration about the drawdown.
Time to come home from Iraq
With Libya and Afghanistan dominating headlines these days, it's been hard to focus on Iraq. But the death of five U.S. soldiers in a rocket attack in Baghdad June 6 has galvanized our attention again.


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London at Night, taken from the South Bank Centre. Big Ben and the London Eye can be seen on the left, whilst the Royal Air Force Memorial, crowned by Sir William Reid Dick's gilt eagle, can be seen in the centre of the GigaPan. There are numerous other hidden details to be discovered here in London the city of the O...
Every year thousands of seabirds return to breed on Skomer Island. For most people the puffin is their favourite character, but what about the kittiwakes, guillemots, razorbills and fulmars too? The most numerous bird on the island however most people never even see; the Manx shearwater only comes ashore to its burrow ...
Panoramic view from the top of St. Paul's Cathedral, London, UK
Lincoln from the South Common, England, United Kingdom. In and Around Lincoln homepage.ntlworld.com/stuart.cox / Flickr www.flickr.com/photos/jondave /
Mont Orgueil (Gorey) Castle, overlooking Gorey Harbour to the south, St. Martin, Jersey, Channel Islands UK
A partial panorama of the beautiful Pantiles in Tunbridge Wells. I was shooting East to include much of the Pantiles area including - Mottrams Kitchen Shop (great to visit!), the Duke of York Pub which I believe also owns the Ragged Trousers Pub opposite (one of my favourites) and of course, the pretty Tourist Informa...
Taken from the Victorian Swanage Pier this panorama covers the seafront and follows the Jurassic coastline round to the Old Harry Rocks at Studland which used to be part of a long stretch of chalk between Purbeck and the Isle of Wight. This image was slighly over exposed and isn't quite as sharp as would have liked. I ...


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"Fashion bloggers Cocks and Morgan... bring humor, heart, and formidable writing skills to this exuberant debut.... The fashion knowledge, eye for Hollywood ridiculousness, and wicked humor that the authors are known for is on full display [and] the wit and depth the authors bring to the project won't disappoint."―PW
"Spoiled is soapy, funny and full of the Fug Girls' trademark Hollywood snark. I want to read the sequel NOW."
―Megan McCafferty, New York Times bestselling author of Bumped and the Jessica Darling series
"Spoiled really is such a FUN read!! I love it, it's dishy, it's girly, it's LA...everything I love."―Joe Zee, Creative Director, ELLE Magazine
"[An] Obsessively readable, smartly subversive take on lifestyles of the rich and narcissistic..."―Kirkus
About the Author
Spoiled is Heather and Jessica's debut YA novel and they are currently working on a second book, coming from Poppy in Spring 2012.


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Tiger Aircraft's AG-5B 2006 models will have AmSafe Aviation Inflatable Restraints as standard equipment for pilot and co-pilot seats and as an option for rear seats. Certification of the air bags is expected to be complete by the end of the year.
Meg Godlewski
Meg Godlewski is a Master CFI.


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Expedition® Camper
Item T491019J LIST: $42.95
18 Reviews
Lightweight, comfortable and durable—this watch might just inspire you to grab your pack and head into the woods.
- Lightweight Outdoor Design
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Timex offers two shipping options for delivery of your order - standard (arrives 5 to 7 business days) and two-day (arrives in two business days). We ship Monday - Friday excluding holidays from Little Rock, Arkansas. Please see our shipping policy for more information.
We want you to love your Timex. Timex gladly accepts returns of unworn, undamaged or defective merchandise for full refund or exchange within 30 days of original purchase. Please see our return policy for more details.


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ACE Personal Trainer Certification Prep Course
Click here to download the registration form
Course Description
Mason Recreation's American Council on Exercise (ACE) Personal Trainer Preparation Course instructed by a certified personal trainer prepares individuals to complete the ACE Personal Trainer Certification Exam. On completion of the course, you will feel better equipped to motivate, empower, challenge, and retain clients for the long term. Exam fees and study materials are reduced for those who participate in the preparation course.
This course does not include the exam for certification. Participation in the course allows for a discounted rate of $249 for the ACE Exam registration fee. Registration for the exam is completed through ACE.
How Do You Register
- Download and complete the Personal Training Preparation Course Registration Form.
- Turn in the completed Personal Training Preparation Course Registration Form at any of our 3 facility front desks and complete payment.
- You will be contacted by email with the course materials website to purchase your study materials through ACE.
Class Dates/Times
|May 16, 2016 - July 25, 2016
|5pm - 9pm
|Aquatic and Fitness Center Classroom
Course Pricing/Registration
Registration Begins: March 21, 2016
|Participant Status
|Payment Location
|College Student
|$250.00 *must provide proof
|AFC or RAC front desk
|AFC or RAC front desk
|**Late Fee (After May 16th)
|AFC or RAC front desk
Required Text
Following the receipt of payment, individuals registered for the course will receive information on how to receive the discounted rate for the ACE course materials.
ACE Study Program: $129.95
(Manual, Exercise Science text, Master the Manual Study Guide and Sample Test)
- ACE Personal Trainer Manual, fifth edition
- ACE Essentials of Exercise Science for Fitness Professionals
- ACE Personal Trainer Manual Study Companion, fifth edition
Key Topics
- Human anatomy, exercise physiology, applied kinesiology, and nutrition
- Principles of adherence, motivation, behavior change, and health psychology
- Communication and teaching techniques
- ACE integrated fitness training model
- Building rapport
- Health and exercise history information assessment
- Functional training: Assessments, programming, and progressions for posture, movement, core, balance, and flexibility
- Physiological assessments
- Resistance training: Programming and progressions
- Cardiorespiratory training: Programming and progressions
- Professional and legal responsibilities, scope of practice, and business strategies for personal trainers
*For more information on upcoming ACE courses, please contact the Director of Fitness (703-993-3935).


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Mucky and wet conditions are no match for your Ovation® Mudsters™ Zip-N-Go Short Boots. Convenient, warm and dry, these rubber and neoprene muck boots keep up with your busy equestrian lifestyle.
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A rubber rain boot that resembles crocodile! This Joules Crockington Wellibob offers an update to a favorite style. Textured rubber delivers waterproof practicality. Rear pull tab and twin elastic panels for easy on/off.


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, Volume 15, Issue 4, pp 409-416
First online:
The Sympathetic Nervous System in Obesity Hypertension
- Thomas E. LohmeierAffiliated withDepartment of Physiology and Biophysics, University of Mississippi Medical Center Email author
- , Radu IliescuAffiliated withDepartment of Physiology and Biophysics, University of Mississippi Medical CenterDepartment of Physiology, University of Medicine and Pharmacology "Gr. T. Popa" Iasi Email author
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.Get Access
Abundant evidence supports a role of the sympathetic nervous system in the pathogenesis of obesity-related hypertension. However, the nature and temporal progression of mechanisms underlying this sympathetically mediated hypertension are incompletely understood. Recent technological advances allowing direct recordings of renal sympathetic nerve activity (RSNA) in conscious animals, together with direct suppression of RSNA by renal denervation and reflex-mediated global sympathetic inhibition in experimental animals and human subjects have been especially valuable in elucidating these mechanisms. These studies strongly support the concept that increased RSNA is the critical mechanism by which increased central sympathetic outflow initiates and maintains reductions in renal excretory function, causing obesity hypertension. Potential determinants of renal sympathoexcitation and the differential mechanisms mediating the effects of renal-specific versus reflex-mediated, global sympathetic inhibition on renal hemodynamics and cardiac autonomic function are discussed. These differential mechanisms may impact the efficacy of current device-based approaches for hypertension therapy.
KeywordsObesity Blood pressure Hypertension Sympathetic nervous system Renin-angiotensin system Renal nerves Renal denervation Baroreflex Baroreflex sensitivity Heart rate Heart rate variability Autonomic nervous system Glomerular filtration rate Renal function Cardiac arrhythmogenesis Device-based therapy
Reference tools
- Title
- The Sympathetic Nervous System in Obesity Hypertension
- Journal
Current Hypertension Reports
Volume 15, Issue 4 , pp 409-416
- Cover Date
- 2013-08
- 10.1007/s11906-013-0356-1
- Print ISSN
- 1522-6417
- Online ISSN
- 1534-3111
- Publisher
- Springer US
- Additional Links
- Topics
- Keywords
- Obesity
- Blood pressure
- Hypertension
- Sympathetic nervous system
- Renin-angiotensin system
- Renal nerves
- Renal denervation
- Baroreflex
- Baroreflex sensitivity
- Heart rate
- Heart rate variability
- Autonomic nervous system
- Glomerular filtration rate
- Renal function
- Cardiac arrhythmogenesis
- Device-based therapy
- Industry Sectors
- Authors
- Thomas E. Lohmeier (1)
- Radu Iliescu (1) (2)
- Author Affiliations
- 1. Department of Physiology and Biophysics, University of Mississippi Medical Center, 2500 North State St, Jackson, MS, 39216-4505, USA
- 2. Department of Physiology, University of Medicine and Pharmacology "Gr. T. Popa" Iasi, 16, University St, Iasi, Romania


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While most of his Mumbai A team mates spent Friday evening planning how to use the match against England to push for state selection, Khan had been at a city hospital where his father had undergone open heart surgery.
Khan's long-time coach, Raju Pathak, said the young bowler had been inconsolable when his father passed away around midnight but decided the best way to honour him would be to play against England.
"He was crying the whole night and was in a state of shock," Pathak told Sunday's Indian Express newspaper. "But this match against England was a big opportunity for him.
"His father was keen to see him bowl against England. So he did what his father would have wanted him to do."
Khan played two Ranji Trophy matches for Mumbai in 2010 before falling off radar and he is trying to make a comeback.
Most of his team mates were unaware of Khan's loss and the bowler sent a text message to one of his friends saying he was playing the match for his father, the newspaper reported.
- Sports & Recreation
- Cricket


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christmas gift
The Holidays Have Arrived With Christmas Gift
Christmas Gift is a universal Christmas themed match three game for you to snuggle up with on a cold winter's night. From the makers of Bespooked, the Halloween themed match three game, this holiday inspired app is just as much fun as its predecessor.
Lory Gil
| December 12


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Horrendous eye ornament by dogzillalivesWatch
©2012-2016 dogzillalives
definitely got's pink eye, eye, eye.
Your Christmas tree must be insane!
Fuck that's cool. how long did that take ?
Don't go poking it!
You dont know where it's been.
You dont know where it's been.
Man, I could build a whole movie around that ugly thing.
I would love to see a tree full of these
Love love LOVE this!
Definitely grotesque.


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The last time I mentioned "Painter of Light" Thomas Kinkade here, it concerned allegedly shady business dealings. Kinkade's newest legal problem: arrested for allegedly driving drunk.
A Monterey County sheriff's deputy initially pulled over Kinkade's Mercedes Benz for a vehicle code violation Friday night, said CHP Officer Robert Lehman. After making contact with the 52-year-old Kinkade, the deputy suspected that he was drunk, Lehman said.
The deputy called the CHP to assist, and an officer performed tests to determine that Kinkade was impaired, Lehman said. The CHP officer arrested Kinkade just after 10 p.m., Lehman said.
Kinkade was booked into the Monterey County Jail on suspicion of misdemeanor drunken driving, Lehman said.
The arresting officer reported that Kinkade was "very polite" during the exchange, Lehman said.
Read on here.
View our privacy policy and terms of service.


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Man Arrested In Connection With Deadly Crash On Highway 99 In SacramentoThe man accused of causing a crash that left one person dead, one injured, and several vehicles damaged has surrendered to authorities.
Proposed Indian Casino Near Galt Drawing Criticism From ResidentsThe proposed casino on Highway 99 north of Twin Cities Road is still in the very early stages, but many in the community say they don't want to take a gamble.
Plane Overshoots Runway At Lodi Airport, Nearly Ends Up On Highway 99The plane broke through a fence, skidded across a frontage road and stopped nose down just short of Highway 99.
Overturned Big Rig Partially Blocks Highway 99 At Dillard RoadNorthbound Highway 99 just south of Elk Grove was partially blocked by a big rig that crashed into the center divider and overturned on Tuesday morning.
Stockton Chain-Reaction Crash Kills Driver, Injures ToddlerThe accident on northbound Highway 99 south of Arch Road closed the road for four hours after the accident.
CHP: Suspected Drunk Driver Caused Fatal Crash On Highway 99California Highway Patrol tracked down a suspected drunk driver who fled the scene after causing a deadly crash on Highway 99.
CHP: 1 Killed In Accident On Highway 99 Near Yuba CityAuthorities say a person was killed in a crash south of Yuba City late Saturday afternoon.
2 Killed In Crash On Highway 99 In SacramentoAuthorities are investigating a crash on Highway 99 that has claimed two lives.
Big Rig Hits Train Trestle, Blocks Traffic On Southbound Highway 99A big rig crash has blocked all traffic on southbound Highway 99 near Elk Grove.
Pedestrian Hit And Killed On Highway 99 In ModestoHighway 99 is back open after a pedestrian was hit and killed while walking on the highway.
Stockton Police Officer Shoots Suspect After Chase On Highway 99Authorities say a Stockton Police officer shot a suspect he had been chasing on Highway 99 Tuesday night.
Fiery Crash Blocks Southbound Highway 99 In SacramentoTwo lanes of southbound Highway 99 just north of Sacramento are back open following a car fire that had blocked all four lanes.


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Omega-3 SLIM® (60 softgels, 1-month supply)
Item## OMW
…is slowly going down and I have lost 2 inches off my waist. Like I said I love this product and recommend it to anyone wanting to lose weight."* — Pam S. "I am very happy with Omega-3 SLIM....After taking this Omega-3 SLIM, I lost 7 lbs. My waistline also decreased so now I can get into my jeans."*…


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Posts Tagged 'Maria Garlick'
On This Day … 2 September
1876 – Frank DEITCH was born in St. Joseph, Michigan 139 years ago. (husband of Isabelle KESSLER, 1st cousin 3x removed -m)
1886 – Frank SCHUMAKER Jr. was born in Austria 129 years ago to Frank Schumaker & Elisabeth ESSERT.
1915 – Maria PENDERGAST Garlick died 100 years ago in Will County, Illinois at 60 years old. (wife of Louis GARLICK, 1st cousin 4x removed -p)
1939 – Harriet DAVIS Asman died 76 years ago in Ann Arbor, Michigan at 67 years old. (wife of John ASMAN Jr, 1st cousin 4x removed -m)
If you have information about any of these people or if you would like more information, please contact me!


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++ ED-NOS Awareness by dimruthienWatch
©2008-2016 dimruthien
Eating Disorder - Not Otherwise Specified.
i suffer from EDNOS since i was 15 :/
Great stamp. I wish more people were aware that there are more eating disorders than just anorexia and bulimia.. and I also wish that there would be more awareness of those with an eating disorder that AREN'T skinny.. I mean, I am aware that everyone sees themselves in different light.. but most people when asked what they see when they see someone with an eating disorder is a girl whose bones are sticking out.. men have eating disorders and bones aren't always shone... It took me a lot of strength to admit that I had an eating disorder, and when I did [put it on facebook] I was told by two different people I was too "heavy" to have an eating disorder. Which just fueled it even more!
<3<3<3<# MUCH love to you for making this.
Thank you for making this stamp.
Great stamp!! ^^
I love you for making this stamp. Thankyou.


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I'm creating a plugin where the user enters 5 numbers in a form, & then these numbers are displayed on a pie chart.
I'm slightly confused by the route I need to take. I would like to use http://www.amcharts.com/
Should I download AmCharts from their website, or use their plugin https://wordpress.org/plugins/amcharts-charts-and-maps/ ? Can I link my plugin, where the user enters their 5 numbers in input fields to this plugin? Or should I download the files & link it up to my plugin this way?
Forgive me if my question sounds silly, this is my first plugin I'm building.


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Fans Knock Back Bubbly After Equestrian Medal
Champagne was in order—and very much in evidence—at London's Greenwich Park on Tuesday afternoon: the British equestrian team had just won the silver medal for Eventing. And while revelers weren't dancing in the streets, they were sipping bubbly in the walkways.
"It would be rude not to!" said attendee Robert Beercock.
After watching the win in the arena, he and four friends bought a bottle of Mumm from the concessions, and they gathered around it the way tailgaters huddle around a beer keg.
Not far off, another group was enjoying the moment. "We drink a lot, especially on special occasions," said Amy Whidburn, referring to the silver medal.
Champagne—available at the venue by the bottle (for about $70) or glass (for about $10) in white and rosé—is common at equine sport events in the U.K., especially at the Badminton and Burghley Horse Trials, which are several-day events like the Olympic Eventing competition. "The Champagne tents are always busy," explained Lexi Proud, a rider who was wearing the brown, chunky Dubarry boots that are a telltale sign of an equestrienne. "It's an expensive sport, so you don't get the hooligans."
"A nicer drink for a nicer class of people," said a friend, excusing himself for the class reference by pointing out that he's an American, therefore allowed to make such observations.
The socializers began to dissipate and return to the stands for the conclusion of the competition, which would determine the individual medals. The Olympic Eventing competition—a three-part sport that includes dressage, cross-country and show jumping—saw a number of royal viewers over the past few days. The Duke and Duchess of Cambridge (Kate and Wills), Prince Harry and the Duchess of Cornwall (Camilla) were all on hand at various points to watch Zara Phillips, granddaughter of the queen and daughter of Princess Anne, who also attended.
Phillips's eighth-place finish helped the British team land silver. Germany won team gold and New Zealand took the bronze. The U.S. team finished seventh and out of the medals in individual. Germany's Michael Jung won the individual medal, followed by Sara Algotsson Ostholt with silver for Sweden and Sandra Auffarth with bronze for Germany.
But with the toasts already given and the rain returning before the individual medal ceremony, the only signs of Champagne were plastic flutes rattling around the stadium seats.
Write to Pia Catton at email@example.com


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derma 1
Another term for dermis.
Oraciones de ejemplo
- Repairing major damage to the derma is a difficult problem facing plastic surgeons.
- The name echinoderm comes from the Greek echinos, meaning hedgehog, and derma, the skin.
- Being lipophilic, the oil can penetrate down through the upper level of the skin to the derma.
Early 18th century: modern Latin, from Greek 'skin'.
Palabras que riman con dermaaffirmer, Burma, Irma, murmur, squirmer, terra firma, wormer
For editors and proofreaders
Saltos de línea: derma
Definición de derma en:
derma 2
sustantivo[mass noun]
Beef or chicken intestine, stuffed and cooked in dishes such as kishke.
Oraciones de ejemplo
- They'd serve you exotic treats like stuffed derma or chopped liver with sliced egg and there would be a live band and floral centerpieces and matchbooks with your friend's name on it embossed in gold.
- The derma came out sliced in five or six pieces and seared on both sides with terrific beef gravy. I gingerly put my fork in expecting the worse, but I was pleasantly surprised.
- The stuffed derma came as two huge slices with thick brown gravy on the side.
From Yiddish derme, plural of darm 'intestine'; related to Old English tharm 'intestine'.
For editors and proofreaders
Saltos de línea: derma
Definición de derma en:
¿Qué te llama la atención de esta palabra o frase?
Los comentarios que no respeten nuestras Normas comunitarias podrían ser moderados o eliminados.
Muy popular en Reino Unido
Muy popular en Australia
= de moda


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Semaphore Park, South Australia, Australia
The Underground HK呈獻:Underground Reunion | Central District
The Underground HK呈獻:Underground Reunion, Grappas Cellar, Jardine House, 1 Connaught Place, Central District, Hong Kong. Sat Sep 20 2014 at 09:00 pm,...
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View Benson Looi's business profile as Managing Director and Chief Experience Officer at Avollusion Limited and see work history, affiliations and more.
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Spines Across the Floor (half) - Slash - Palco Principal
A música de MOÇAMBIQUE está no Palco Principal: um espaço onde os artistas, os ouvintes e os profissionais do mundo da música se encontram. Presente em...
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Pure Yoga is dedicated to serving the yoga community with 6 yoga centers in Hong Kong. Watch this space for our latest yoga promotions!
Event: Hong Kong: Underground Reunion (20-9-14) - Features - GFM.FM
The third act is Benson Looi of slash!SAKURA!slash!, whose emotional and melodic guitar riffs have once lured many heavyweight musicians ...
Underground Reunion | Hong Kong Gigs Grappa's Cellar | HK Magazine
To honor the 10th anniversary of The Underground, six disbanded local groups—as well as musicians on hiatus—are coming together for one night only.
Brace yourselves for the lineup: first up is Benson Looi of Slash!Sakura!Slash!, whose emotional and melodic guitar riffs have once lured many heavyweight ...
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Benson Looi | 好戏网
Benson Looi. Underground Reunion - The Underground HK | 好戏网 · Underground Reunion - The Underground... 2014-09-20 21:30 - 23:59, 音乐 ...
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hkclubbing including ALL nightlife events listings, party photos, bars, restaurants and nightclubs directory. Come and join us to have fun now!
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Jeanette Faglie. Did not leave any message. September 16, 2013 5:27 pm. Benson Looi. Sponsored links. Submit a Report about 07932360924 phone number:.
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Noughts and Exes | Freelyshout
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Time Out Hong Kong | Music - C&R
... a setback with the closure of Hollywood Road's Mink bar, and with it the loss of the monthly acoustic nights organised by Benson Looi. The always-crowded .
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Our Brian Hutchinson is in Hong Kong and tweeting posts and photos from the protests.
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Underground Reunion - The Underground HK When: 20 Sep 2014 Sat 21:30 Where: Grappa's Cellar ⇒香港独立乐队音乐会-The Underground HK So people got this crazy idea of...
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Photo Details
Composite of scenes and people related to the laying of the Atlantic telegraph cable and the invention of the telegraph including B. Franklin, Cyrus W. Field & Prof. Morse. Includes Pres. Johnson reading the morning news from Europe, and Queen Victoria reading the news from America with ship at center.
- Periodical illustrations--1860-1870.
- Wood engravings--1860-1870.
- 1 print (2 p.) : wood engraving.
- Technology and U.S. Library of Congress
- Miscellaneous Items in High Demand
- Ships--1860-1870.
- Telegraph--1860-1870.
- Telecommunication cables--1860-1870.
- Inventors--1860-1870.
Forbes, Edwin, 1839-1895 , artist
- Illus. in: Harper's weekly, 1865 Aug. 12, pp. 504-505.


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"Kirthar National Park" Kirthar Range by besal
Kirthar Range Travel Guide: 12 reviews and 45 photos
Pakistan?s national parks are areas of natural-untouched beauty, where the landscape, wildlife and vegetation flourish. And somehow, with various NGO?s insistence, Government of Pakistan protects and preserves them in their natural state. No exploitation is allowed. Hunting (restricted access), cultivation, mining, etc are strictly forbidden. These regulations and restriction, and no proper roads have left these sanctuaries in their natural state, where both flora and fauna flourish in the picturesque landscape.
There are more than 14 natural parks in Pakistan and one of them is in Sindh.
This page is about Kirthar National Park, Pakistan?s second largest reserve, and I would also like to call it the "GRAND CANYON OF SINDH". This park was included in United Nations world list on National Parks in 1974. The park is situated in the south-western part of Sindh, stretching from north-east of Karachi to Dadu/Larkana district, and bisecting Sindh-Balochistan border. The total area of the park is more than 308,000 hectares. SindhWildlife manages the park, where they have developed two main centers: Khar and Kharchat.
Kirthar belongs to IUCN Category II protected area, designated mainly for ecosystem preservation. Therefore I believe there will be no MacDonalds, KFC, or Pizza Hut cropping up in the near future. Though SHELL did try to mine for oil, but thanks to our public and some NGOs, this move was check-mated. And this is one reason why the landscape and wildlife are well preserved because there are no easily accessible roads, with some security concern.
One can go to Khar from Karachi in one?s own car, but Kharchat is accessible by 4x4 only. Khar is approx. 95 km from Karachi near Hub Dam, while Kharchat is more than 160 km from Karachi via Super highway. The best time to visit is from October to March, which are considered cooler months. There are several rest houses, with running water and cooking facilities, in both locations, and can be easily booked through the Sindh Wildlife in Karachi. They also rent tents if anyone is interested. Food could be arranged, if ordered well in advance, but it is advisable to take your own food, drinks and beddings.
The landscape of Kirthar hills forms a natural refuge for all kinds of wildlife and vegetation. Various forms of mammals and reptiles such as gazelles, Ibex, sheep, cats, wolf, lizards, porcupines, snakes, partridges, eagles, vultures, sand grouse, migratory birds, etc could be seen inside the park (if one is lucky). In addition the vegetation of the park comprises of various forms of shrubbery, flowers, and trees.
Other than the natural landscape, one can also have an Indiana Jones type of an archelogical experience. There are several 18th century Chaukundi style tombs at Taung, pre-historic rock paintings and archaeological remains at Koh Tarash, and one of the world largest fort, RaniKot within its boundry. Ranikot is two hours by jeep from Karchat. Another way to access RaniKot is from Saan, about four hours from Karachi via Hyderabad.
My present tips are of our visit to Khar in mid-October 2007. We took our own cars, Sedans, and surprisingly the roads were well maintained. With some detours due to washed away roads. When we reached Khar, we realized that one really needs a 4x4. I have no idea how my Honda City climbed that gravel track.
On a lazy Sunday morning/afternoon the drive towards Khar/Hub Dam is quite pleasant and takes one away from the city life.
- Pros:Unexplored, mini-grand canyon, natural untouched beauty
- Cons:Minimal accomodation, requries 4x4 for exploration
- In a nutshell:GRAND CANYON OF SINDH (on a miniscule scale)
Reviews (12)
The dam provides fresh water to the inhabitant of Karachi. The Dam entrance is situated on teh Hub Road, 18 km before... more travel advice
This grave of an unknow saint/pir is situated very close to the Hub Dam. Maybe on my next trip I will stop to check... more travel advice
The vegetation of the park comprises of various forms of shrubbery, flowers, and trees. It is said that during monsoon,... more travel advice
These ponds were created when flash floods passed through this ravine, resulting wipeout for roads. Now one had to... more travel advice
Travelogues (2)
- 1
Comments (4)
That would be great place to visit, it must be real thrill to see crocodille's mouth open, teeth that sharp. I wouldn't like to be his meal but would love to see him and other animals from safe place.
so glad to c pple travellin to this region & exploring..personally im very fond of this area & even working on a thesis design project to promote tourism in this region..i hav been to the kirthar Ranges but ur tips and pics are really informative..tHanx !
Beautiful destination. I liked your idea of warming the food, I shall use this method next time. The warning of danger is well written, many people become adventurous after seeing few people, forget about family. But predators always watch! good one!
xclent tips. this is surely boyz destination :-) i am glad somebody covered this destination. next project - karachat where you can take wildlife pix?
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Latest Activity in Kirthar Range
- Posted in Travel Pakistan Forum "Re: Karakoram Highway in winter"
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Top 10 Pages
- Top 5 Page for this destination Karachi Intro, 76 reviews, 307 photos, 3 travelogues
- Thatta Intro, 20 reviews, 80 photos, 5 travelogues
- Islamabad Intro, 12 reviews, 64 photos, 2 travelogues
- Khewra Intro, 18 reviews, 50 photos
- Taxila Intro, 16 reviews, 45 photos
- Gwadar Intro, 11 reviews, 46 photos
- Kirthar Range Intro, 12 reviews, 45 photos, 2 travelogues
- Top 5 Page for this destination Naran Intro, 25 reviews, 26 photos, 2 travelogues
- Muzaffarabad Intro, 10 reviews, 37 photos
- Top 5 Page for this destination Hunza Intro, 12 reviews, 34 photos


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Palo Duro High School Air Force Junior ROTC cadets Raven Rodriguez-Aragon, from far right, Anna Reyes and Eden Gutierrez watch as cadets Jody Martinez, Greg Anderson, Gabe Trevino, Kyle Stommel and Louis Fuentes have their photo taken recently with Jenny Marlowe, Miss New Mexico at the Tucumcari, N.M., Rotary Club's annual Air Show.
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text: wind energy Arizona Universities to Collaborate on Energy Research By Justin Regan • Oct 7, 2014 Robert Rappaport/Arizona Public Media A new energy policy will bring the state's three universities together to find solutions to Arizona's future energy needs. As Arizona Public Radio's Justin Regan reports, it's the first collaboration of its kind for the state. Obama Administration to Fast Track Renewable Energy Projects President Obama announced seven large solar and wind projects in the west will be expedited. The announcement comes on the first day of the national clean energy summit. Nevada Senator Harry Reid kicked off the renewable energy summit in Las Vegas with a call to replace coal with wind and solar. "Every year we spend hundreds of millions of dollars buying coal from other states to burn in Nevada," Reid said. "It's time to make a different choice a choice that brings new clean energy industries and jobs to Nevada, a choice to invest in our own natural resources."


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Over at http://www.sciencebasedmedicine.org/ we're using Jetpack for commenting. We have "Comment author must have a previously approved comment" checked, and "An administrator must always approve the comment" unchecked but all users are having their comments require moderation no matter their previous amount of approved comments.
The number of links required for automatic moderation is set to 3 and this is happening with comments with even zero links.
I've done some searching here and via Google and one solution was to clear the word lists for moderation and spam to see if that helps. We've tried that and it hasn't helped at all.
I've also tried simply toggling the settings on/off (because you never know) and that didn't work either.
Commenting is very active on this site, but we've also got a problem with sock puppets and fake posters that requires some fairly stringent moderation.
Any ideas?


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Goodreads helps you keep track of books you want to read.
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Preview — The Pentateuch by Joseph Blenkinsopp
The Pentateuch: An Introduction to the First Five Books of the Bible (Anchor Bible Reference Library)
A world-famous biblical scholar presents the only one-volume, comprehensive, and up-to-date analysis of the origin and meaning of the Pentateuch, and the extraordinary scholarship it has inspired.
Paperback, 288 pages
Published September 1st 1992 by Anchor Bible
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Oct 30, 2012 Paige rated it it was ok
You definitely need to be prepared for a thorough outline of biblical history when picking up this book. I found it difficult to invest 100% while reading, but that might be a result of the multiple other books I'm required to read for class. Very informative and certainly useful but a tad dry in my opinion.
Nov 29, 2011 Rachel rated it it was ok
Shelves: nonfiction
This book is probably the least fascinating of the ones I read for Old Testament this semester. I like the insight into the structure a lot, and that part seems useful and important for future study.
Jul 26, 2013 Matthew Henry rated it did not like it · review of another edition
A book that works very hard at everything but treating the Pentateuch as what it is. The one thing you walk away with is that the author does not accept the historicity of the books.
Oct 29, 2012 Emily rated it liked it
Very technical read, especially the first chapter which condenses two centuries of the history of biblical scholarship into 40-50 pages. After that it gets better.
Feb 15, 2009 Nicholas added it · review of another edition
The Pentateuch: An Introduction to the First Five Books of the Bible (Anchor Bible Reference Library) by Joseph Blenkinsopp (1992)
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Anchor Bible Reference Library (1 - 10 of 36 books)
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A 3-D carbon nanotube mesh enables rat spinal tissue sections to reconnect in culture.
AACR Q&A: Angelika Amon
April 19, 2016|
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Patients with neonatal progeroid syndrome lack a glucose-releasing hormone, while people with insulin resistance have an abundance.
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"Ego dissolution," and other things that happen to the human brain on LSD
April 11, 2016|
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Researchers create a new tree of life, largely composed of mystery bacteria.
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The immune cells—known for clearing dead cells—also chew up live progenitors in neurogenic regions of mouse brains.
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2 British Men Drown while Rafting in South India
Posted: 05/26/2012 - A police official says two British men have drowned after their raft overturned and capsized in a river in southern India.
Posted: 05/26/2012 - A police official says two British men have drowned after their raft overturned and capsized in a river in southern India.
Posted: 05/26/2012 - The visit of Indian Prime Minister Manmohan Singh to Myanmar on Sunday is the latest sign that India now believes it needs to assert its presence in its eastern neighbor.
Posted: 05/26/2012 - Egyptian presidential candidate Ahmed Shafiq has paid tribute to the uprising that toppled Hosni Mubarak and vowed not to try and "recreate" the old regime.
Posted: 05/26/2012 - The president of troubled Spanish lender, Bankia, says the bank will emerge as a solid financial entity that will not need further recapitalization after it receives (euro) 19 billion ($23.8 billion) in state aid it has asked for.
Posted: 05/25/2012 - Hurricane Bud has weakened to a Category 2 storm in the Pacific as it approaches Mexico's coast.
Posted: 05/25/2012 - A privately bankrolled spacecraft is getting ever closer to the International Space Station for a historic docking Friday.
Posted: 05/24/2012 - Bud has turned into a major hurricane off Mexico's Pacific Coast.
Posted: 05/24/2012 - Janet Jackson, Alec Baldwin and Adrien Brody have brought a touch of Hollywood glamour to the south of France for amfAR's Cinema Against AIDS gala.
Posted: 05/24/2012 - A tropical storm warning has been issued for the coast of Mexico as Hurricane Bud gains strength in the Pacific.
Posted: 05/23/2012 - The U.S. National Hurricane Center says Hurricane Bud has formed off the southwestern coast of Mexico.
Posted: 05/23/2012 - Despite favorable conditions, Tropical Storm Bud in the Pacific has yet to strengthen.
Posted: 05/22/2012 - Activists and state media say a bomb has exploded in the Syrian capital, killing at least five people.
Posted: 05/21/2012 - Yemeni officials say 20 soldiers died when a suicide bomber blew himself up at a military parade drill in the capital Sanaa.
Posted: 05/21/2012 - A French prosecutor has opened a preliminary investigation into allegations of rape in a Washington hotel by former IMF chief and one-time French presidential hopeful Dominique Strauss-Kahn.
Posted: 05/20/2012 - Italian quake, Guatemalan volcano, Taiwan China policy, Chinese miner rescued, Syrian violence, Libyan vote, Egypt elections, Yemen militants killed...
Posted: 05/19/2012 - Here is a look at some of Greece's problems as it struggles to pay its debts...
Posted: 05/18/2012 - A strong 6.2-magnitude earthquake has struck off Chile's southern coast, but the authorities say it wasn't felt on land and discounted the possibility of a tsunami.
Posted: 05/18/2012 - Israeli Prime Minister Benjamin Netanyahu says he is skeptical that Iran will agree to halt its nuclear program.
Posted: 05/18/2012 - Tropical Depression Aletta hangs on despite high shears and dry air. Meanwhile, another potential tropical disturbance is developing in the Pacific.
Posted: 05/17/2012 - A rocket has lifted off in Japan in the country's first commercial launch of a foreign satellite -- one from South Korea designed to monitor the environment.
Updated: 05/18/2012 - Aletta has weakened to a tropical depression as it swirls far out over the Pacific.
Posted: 05/16/2012 - A Russian-made Soyuz craft carrying three astronauts has docked with the International Space Station, putting the crew in place for the imminent arrival of the first ever privately owned cargo ship to the orbiting lab.
Posted: 05/16/2012 - Tropical Storm Aletta is weakening is it spins far out over the Pacific.
Posted: 05/16/2012 - Twenty years after the opening shots of the Bosnian War, former Bosnian Serb military commander Gen. Ratko Mladic has gone on trial at a UN tribunal on 11 charges of genocide, crimes against humanity and war crimes.
Posted: 05/15/2012 - Ex-News of the World editor and News International chief executive Rebekah Brooks says she and her husband will face charges over Britain's tabloid phone hacking scandal.


text:
Monkey Island Explorer
Its an explorer tool for Monkey Island 1 and 2: Special Editions. It does the following:
[Edit] Updated - now supports MI2-SE and the Xbox/iPhone versions of the games.
[Edit 2] Updated - now plays and dumps audio and includes annotation support. See my site and the readme for more information.
Download it here.
Cool, I'll have to play with it a bit.
I'm sorry Ben, I'm afraid this name is already copyrighted.
But I won't press charges ;)
Hee, a real blast from the past. I await my c+d letter from you ;)
Are there plans to allow you to dump the music with this someday?
No, unfortunately that was never intended to be a feature of -- oh... did you mean Ben? :(
Looks cool. I forgot, but that other extracter didn't support voice files did it?
Cause we need to fix the narrator's voice and replace it with blank files.
Hey, this looks great! Any chance for a mac version?
Or has anybody had the chance to test it with the mac version yet?
I already own the iPhone version, but I'd like to do some visual mods to the desktop version.
Updated with support for the Xbox360 version of the game.
Very useful, and it would be nice if you made it possible to sort the list by name.
Any chance for an update to support MI2 as well?
And while we're at it, the XWA-extractor doesn't work with the music files from MI2. Any chance for an update of that as well? ;)
When it unlocks, yes :)
The xwa extractor wont work with the music files yet as they (together with all the other resource files) are still encrypted by steam. Hopefully they'll be ok once it unlocks.
Ah, I see. I wasn't sure what Steam did to those files prior to unlocking.
Thanks to Serge I've updated Monkey Island Explorer to support MI2-SE. Its not fully optimised or anything yet - but it'll work for browsing the pak and extracting images and files.
It'll also work with the Xbox (if you use the XBDecompress tool) and iPhone versions should you feel the need to delve into them.
Get it here.
Awesome work as always, Ben! The image dumping is especially useful for Mi2 SE >:D
@elTee: were YOU the guy who made that? I am now slowly remembering it... but what was the point of it all?
I've updated the program again.
This version adds support for playing and dumping the audio from both games (music, voice and sfx) and introduces annotation support.
Annotations contain alternative filenames for audio that are more descriptive than those present in the original audio files. Eg the MI2 speech annotation file means that instead of a filename of "5840″ you will instead see "Stan's Kozy Krypts– A Place to Spend Eternity, Not a Fortune."
Annotation files are included for MI2 speech and commentary. If you make any annotation files please send them to me so I can include them in the next release.
Get it here.
So does that mean it's possible to rip out the narrator's voice and replace it with blank audio files?
Its certainly possible yes. However you'd need to build another wavebank, which is a little fiddly but I've successfully done.
Could you add command line support?
I'd like to use it automated by the patching tool, which I'm writing for the classic talkie CD project.
It should support individual files, ie. we need just those two classic resource files of the pak.
And it should support extracting entire wavebanks, since we use most of the samples anyways.
The tool should terminate automatically and return an error code when command line extracting is done.
Is it okay to re-distribute the tool with the patch? I would keep "Monkey Island Explorer.html" intact, of course.
EDIT: I don't need it that badly anymore. I noticed the source is available in extractpak and changed it to only extract what I need.
Dear Bgbennyboy,
Could you add pvr support to Monkey island explorer.
MISE2 for iPhone use pvr and crushed apple PNG files.
(MISE 1 used normal png)
I could save pvr files with your tool, but I did not find any application to edit them.
Imagination texture tool can not handle them, because this files created with apple texturetool.
I saw pvr from games and created with imagination texture tool with hex editor, and 2 files header are different.
I found an OSX app (atPeek), that can explore iPhone apps ipa files (ipa files are actually zip archives).
And atPeek can extracts and converts from crushed Apple png and pvr (power VR texture files) to normal (editable) PNG files.
I checked Monkey.Island.2.Special.Edition-v1.1-most_uniQue.ipa with atPeek.
( I checked free version also, but the result is same)
I was able to extract crushed PNG files from game's main directory ( BKG_iPad_bonusFeatures.png etc) and I was able to edit them.
I was able to extract and convert some pvr files with atPeek an other game file. (SW_ Hoth 1.0.ipa, light version is free)
But I'm trouble with MISE 2 , because pvr files are in pak archive. atPeek can not handle pak files.
So I extract pak files with Monkey explorer and put files to ipa file.
But atPeek can not recognize them. I think pvr files are corrupt.
(I compared mise2 PVR and Hoth pvr with hex editor and I did not see PVR! characters in the first line in MISE2's PVR files)
I can open The pvr texture files, which extracted from SW_Hoth.ipa with Imagination PVRTexToolGUI utility.
But it can not open pvr texrures from MISE 2.
May be Monkey explorer produce wrong/corrupt pvr files.
Is there any decryption process during extraction?
Dear Bgbennyboy,
Help me, if have you got any idea....
I saw Monkey Island Explorer extracted PVR files.
First line:
4 ‹ í˝`I–%&/mĘ{JőJ×ŕtˇ
Corret PVR files first line:
4 � ŞŞ đ đ PVR!
PVR! is missing frm extracted files
As far as I know there are no problems with the tool. I've tested it with the iphone/ipad lite version of MI2 and it works fine. All other file types work and dump correctly.
The problem isn't with the tool - its with the pvr files. I know nothing about that particular file but it sounds like they've changed the header slightly.
I extracted pvr texture files from other iPhone games. And I can open them with imagination PVR texture tool.
But I extracted pak files of MISE 2 full and light version with Monkey explorer and I can not open them.
It's great shame, but I can not edit game files.
Yes, because the pvr files are probably in a slightly different format. Just as the dds images are in the other versions.
If I have a fortunate UI elements are in PNG, that I could translate them.
I've had a quick look - it looks to me like a pvr texture with a truncated or modified header (there's the 4 byte header size and then width/height dwords - possibly more?)
A bit of googling reveals that iphone developers sometimes just have the raw PVRTC texture with a minimal header. Handy for saving space when you've got lots of images and dont want to have the full 52 byte header tagged on each image.
Is it possible to repair header ?
I dont have the time to look into it, sorry.
Not et all.
Thank you very much your great tools.
I have a trouble again.
So We made localised (Hungarian) version of Monkey Island SE 1 and 2 for PC and iPhone.
I just bought a JTAG XBOX 360, and I would like to make localisation for XBOX also.
I try Monkey Island Explorer with Xbox version Monkey1.pak, but it can not handle (version 0.4)
I used xbdecompress, than Eplorer opened decompressed monkey1.pak, but extracted dds files are corrupted, I can not open it with paint.net
( it worked well with PC version)
Please help
Version 0.4 don not work
Version 0.2 work with decompresed monkey1.pak, but do not work with monkey2.pak
Version 0.4 should work fine to open either xbox version, provided you've used XBDecompress to decompress the pak file.
There does seem to be an issue with the dds files though, I'll have a quick look into it now
Dear bgbennyboy,
I tried 0.4 with decompressed pak and did not work for me.
When I would like to see an image Ialways receive error mesage.
Fixed it - was a stupid class overriding bug - the big endian detection got ignored. I'll upload new version later.
I've tried it with the demo versions of xbox mi1 and 2 that I was sent and it opens and works perfectly with both when XBDecompress has first been used to decompress the pak file.
[Edit] Done - see my site for the new version.
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text:
MONTGOMERY, Ala. (AP) - Gov. Bob Riley says Alabama will offer a
compromise in its ongoing dispute with a federal agency over claims
that the state has been receiving too much federal money for the
Riley made the remark on Monday after meeting with the director
of the federal Center for Medicaid and State Operations.
The federal government argues Alabama was overpaid by up to $300
million during the past four years to finance its Medicaid program.
The dispute centers on how Alabama calculates its share of the cost
of providing health care to the poor and disabled.
Federal officials say Alabama's definition causes federal
payments to the state to increase.
Riley says the dispute is hampering his ability to plan annual
(Copyright 2009 by The Associated Press. All Rights Reserved.)


text:
By DAVID SKOLNICK
Actor Steve Buscemi, best
known for playing colorful criminals on television and in movies, had a different role during his visit to Youngstown: political supporter.
Buscemi headlined a Thursday event for Michele Lepore-Hagan, who is running in the Democratic primary in May for the 58th Ohio House District. The seat is currently held by her husband, Robert, who cannot seek re-election this year
because of the state's term-limits law.
The event at Overture at the DeYor Performing Arts Center drew a crowd of about 350 at $50 a ticket.
Michele and Jo Andres, Buscemi's wife, danced together at Ohio University and shared an apartment in New York City, and along with their husbands have been friends for years. Buscemi and his wife also are close friends with Michele's sister, Nanette Lepore, a fashion designer, and her husband, Robert Savage, a painter. Nanette designs many of Andres' dresses, Buscemi said.
"We just all got along and spent a lot of time together," Buscemi said in an exclusive interview with The Vindicator. "We often had conversations geared toward politics."
Buscemi said he's been impressed with Robert Hagan's political career.
"To have somebody be that progressive and liberal and be proud of it and really work toward certain values" is to be admired, he said.
Buscemi said he always considered the Hagans a team.
"It doesn't surprise me that Michele is getting in on the act now, as she's been Bob's partner," he said. "Bob's been the person in the public eye, but Michele's been his partner through and through. Now it's time for her to shine."
When he found out Lepore-Hagan was running for the Ohio House, Buscemi said he volunteered to come to the area to help the effort.
"Any excuse to come to Youngstown," he said. "I like Youngstown. I didn't grow up here, but I know the history. It's gone through some tough times. It was once a real thriving working-class town. It's not that different from how I grew up in Brooklyn and Long Island, [N.Y.]. These are the people I relate to."
When asked if he can draw any inspiration from the organized-crime history of Youngstown for characters he plays — including Nucky Thompson, a powerful and corrupt Atlantic City politician during Prohibition on HBO's "Boardwalk Empire" — Buscemi said with a laugh, "We had that covered in New York as well."
But he acknowledged Youngstown's mob history makes the area "colorful."
He also remembered that Paulie Walnuts, a character on HBO's "The Sopranos" — a show on which Buscemi played Tony Soprano's cousin for three seasons — "did his time in Youngstown" for a gun-possession charge.
Along with a busload of other actors, Buscemi campaigned in Youngstown in 2004 for Democrat John Kerry's unsuccessful presidential campaign, and was an early supporter of Bill de Blasio, elected last year as mayor of New York City.
Buscemi's best-known characters on TV and in film are criminals, including memorable roles in "Reservoir Dogs," "Fargo," and "King of New York."
The other Democrats seeking the 58th District seat are Councilwoman Janet Tarpley, Cynthia L. McWilson and Michael E. O'Hara. Like Lepore-Hagan, they all reside in Youngstown. There isn't a Republican candidate in the race.
Who cares about an endorsement from some goofy Hollywood actor??
When will this Valley wake up and get rid of these teet sucking parasites. They just want to continue acting famous and travelling around on your dime. This tree hugger will kill the shale boom in this Valley, she is worse than her husband. Wake up this Valley will never grow with the likes of this family.
NO TO HAGAN ! She will become another career politician,or as DonMGirard said,a sucking parasitie.
Exactly what qualifications does this woman claim to have???
This article is actually pretty funny because nowhere in here does it speak of her "credentials." Ok, so she knows some actor. Big deal. I have Lou Holtz's phone number programmed in my phone, so does that make me more of a "reputable" person? Heck no. Looking at this list of candidates, none of them are actually qualified to represent the district. Just another Dem in office, riding the coat tails of their loser spouse!
I think most commenting here fail to give Ms. Lepore-Hagan her due credit. I believe she has been partners with Buckwheat for 28 years and can still look at his pizza-face. That's something! Quite frankly, the mere sound of the name "Hagan" is like nails on a chalkboard to me. All I can visualize is Buckwheat and his brother, Taxin' Tim, slopping at the public trough with their father, the ultimate hand-out king, passing out more freebies. We have no aristocracy in the US past the Kennedy clan and this seat doesn't belong to a family. I would find it hilarious if the local Democrat Party endorses one of the other candidates in the race. But, I'm not sure the ambulance chaser will permit that to happen.
This is what I find offensive. It is ok to have opinions. It is ok to have differences. It is ok not to agree (you don't have to vote for someone you don't believe in). It is NOT ok to be mean and to call people names and to be so very negative. This is the kind of petty negative stuff that actually harms our society. You may not be aware, but you are feeding the bi-partisan void that is splitting our country. TEHO (To each his own) is what we should all be workinig towards. Silly foolish optimist? Yup and very proud of that. I like being half full.
Of the few times I've seem Buscemi on TV, he has been in a "creepy" role.
Like so many television programs, this is a replay.
Gotta love ol' "Crazy Eyes."
Tarpley, McWilson and O'hara are pulling their funds together for a petting zoo fundraiser at one of the above candidates backyard locations.
Maybe Obama will see this trend and have Michelle run in 2016? Please, Please, Please.....I love giving my money away to the less deserving.
Sorry for being intemperate with my descriptions but you may have a point. I will attempt to refrain from using offensive and disparaging terms like "Hagan" and "democrat" in future posts.
She is an idiot just like her husband. What qualifications does she have for this position. Then again Obama didn't have the qualifications and the American people elected this idiot twice. Go figure.
and all the angry cons come out...thank God, a virulent minority here and the majority of the country
remember, Romney landslide, losers
It goes without saying that she will win the election. She is a Democrat and this is the Mahoning Valley after all. You have to wonder how desperate Bob Hagan is to keep his sticky fingers in state government that he puts up his wife to run in his place. Term limits were put in place to get political hacks out of the system and bring in new blood. What we'll get now is Bob Hagan with lipstick.
Well, I have to admit, she is much better looking.
In politics and the business world, that helps more than many realize.
This is why the Vindicator is considered a joke by anyone who's read a real newspaper in a real city. Front page story complete with picture granting free advertising worth thousands of $$ for one candidate who's only "credential" is the same last name as the term limited incumbent. But then again this is the same protector of ethics that skewered Engler via an editorial for his tax problems while constantly promoting "Vindy Radio" with their own tax scofflaw Mr. Free.