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A West Tawakoni man, accused of attacking firefighters trying to save his house last month, spent Christmas in the custody of the Hunt County Jail.
William Alton Easterling, 70, may be out by New Year's Day however, after a judge agreed Thursday to reduce his bonds on charges of aggravated assault against a public servant. An attorney was appointed for Easterling Dec.17.
During a hearing Thursday, 354th District Court Judge Richard A. Beacom lowered Easterling's bonds from $35,000 to $20,000 on each count.
Easterling was taken into custody after he allegedly attacked personnel responding to a fire at his residence.
Firefighters responded on the night of Nov.24 to a call of a structure fire at Easterling's home on Ideal Circle in West Tawakoni. Easterling was accused of attempting to run over the fire personnel working to bring the fire under control.
Local News
Bonds reduced in firefighter assault case
A West Tawakoni man, accused of attacking firefighters trying to save his house last month, spent Christmas in the custody of the Hunt County Jail.
- Local News
Bowie Elementary focus of school bond forum
Bowie Elementary School was the main topic of discussion during an informational bond presentation and facility tour at the school Tuesday.
- Two bids received on Exchange Building
Holocaust survivor recounts life in concentration camp
An estimated 1.1 million people were killed in the Auschwitz concentration camp during World War II.
GISD hosting public forum tonight on bond issue
With the start of early voting for the May 10 Greenville ISD election less than a week away, school district officials are presenting another public forum tonight concerning the $72 million bond package which will be included on the ballot.
Trial set in shootings case
A local man is facing trial this week on multiple charges in connection with two shootings in Greenville last summer.
Blacklands Corridor meeting scheduled next month
Another public meeting has been scheduled to update plans addressing future transportation issues along the Blacklands Corridor between Greenville and the Dallas area.
Safely disposing of unwanted medications
The Greenville Police Department, GEUS and American Medical Response are teaming up to offer local residents a chance to safely dispose of their unused and/or outdated prescription medications.
Police to increase patrols after two incidents
Two incidents last week in Commerce should have residents on alert when walking through poorly-lit areas, according to Commerce Police Chief Kerry Crews.
Porter-Brathwaite to serve as new human resources director
City Manager Massoud Ebrahim has announced the hiring of Jaynice Porter- Brathwaite as the new Human Resources Director for the city. The appointment follows the retirement this winter of Barry Robinson after 33 years of service.
Keeping it 'green' in Greenville
Later this week, local school children will bring home a tree seedling, with plans to find a place for it in the back yard.
- More Local News Headlines
- Bowie Elementary focus of school bond forum


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Within the span of a week, the Eastern Seaboard of the U.S. was rattled by an earthquake and slammed by Hurricane Irene. Severe weather can strike unexpectedly, so venue managers need to know what to do in advance to protect their facilities and guests. One resource to turn to is the International Association of Venue Managers' Severe Weather Planning Guide.
The comprehensive, 70-page book explains how to build relationships with emergency management personnel, establish a command center, and create a severe-weather-event team. It outlines how to monitor weather conditions and properly communicate with staff, guests, event presenters, and others. The guide, updated in 2011, also includes a template that venue managers can use to create their own hazardous-weather plan.
"The safety and security of venue guests are top priorities at IAVM," said Vicki Hawarden, CMP, president and chief executive officer at IAVM, based in Coppell, Texas. "This organization is committed to providing innovative safety and security guidelines, resources, and training that are pertinent and useful to our membership. They help them protect their No. 1 priority¬¬—the lives of the guests who attend their events."
In addition to the planning guide, IAVM offers the Academy of Venue Safety and Security, an intensive, five-day training program in security planning and management. For more information, go to at http://www.IAVM.org/AVSS www.iavm.org/avss.
In November, IAVM hosts the annual International Crowd Management Conference, which focuses on the skills venue managers need for safe and effective crowd control. The 2011 conference runs November 6–9 in Dallas. IAVM also offers a training program in which participants become "Trained Crowd Managers."
While the guide is written primarily for venue managers, meeting planners could use several parts of the plan to help them monitor and address severe weather issues. The guide costs $75 for IAVM members and $125 for nonmembers. For more information on the planning guide or any other emergency-preparedness resources from IAVM, go to IAVM's Web site.


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NASHVILLE, Tenn. – Officials have reopened all lanes of Briley Parkway southbound in West Nashville after a fatal motorcycle crash.
The crash happened around 11:20 a.m. Thursday between Centennial Boulevard and White Bridge Road.
A motorcycle went down an embankment, and the rider was killed. The identity of the motorcyclist was not released.


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New website made easier for voter registration
The Colorado Secretary of State's Office has made some changes to its website to make it easier for people to register to vote or make changes to their registrations. The website,…
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(Buenos Aires, El Calafate, El Chaltén, Lago Del Desierto)
Travel to El Calafate for an exciting day of Ice trekking on the Perito Moreno glacier, right in the Glaciares National Park. Then move up to El Chalten, world renown for Fitz Roy Mount and its numerous hiking trails. Lago del Desierto is right on the border with Chile, but still a part of the Argentinian Patagonia. A unique lodge set along the mountain range and giving you the opportunity to enjoy some fly fishing! (Available seasonally only from November to May)
This trip encompasses adventure, lovely peaceful walks and the rewarding experience of hiking high mountains.
A private transfer between the airport (International) and city of Buenos Aires with a professional driver and an English-speaking guide is provided.
The Argentine National Immigration Directorate (DNM) has launched an online method of payment to enable payment of the reciprocity fee via credit card. Travellers can now pay this fee through the Provincia Pagos payment system. US, Australian and Canadian citizens can pay the reciprocity fee before entering Argentina by accessing the following websites: www.provinciapagos.com.ar and www.migraciones.gov.ar.
How can I pay the Reciprocity Fee Online?
1.Register at www.provinciapagos.com.ar and obtain an entry code. 2.Complete the form including personal and credit card details . This information and the entry code will be sent electronically to the DNM. 3.After payment is processed, print the receipt. 4.Upon arrival in Argentina, go to the DNM Office and present the printed receipt. 5.The receipt will be scanned by DNM staff and the data will be validated to enable entry to Argentina.
Subject to change without notice.
The Mine Hotel is a beautiful and modern boutique hotel placed in the bohemian Palermo Soho, the main center of art and entertainment of Buenos Aries. The friendly staff, gorgeous gardens, the unique decoration and the most comfortable rooms will make this hotel the best choice to stay in this beautiful city.
Sleep in this morning and relax at your hotel.
A private airport transfer with a professional driver and English-speaking guide is included (between Buenos Aires' hotels and domestic airport or vice versa)
Fly from Buenos Aires domestic airport to El Calafate. Please note that flights are subject to changes based on availability. The flight duration is approximately 3 hours and 11 minutes.
Enjoy a private airport transfer with your very own vehicle, driver and English speaking guide.
Welcome to Alto Calafate Hotel, where the beauty of the landscape is combined with the functionality of the ambiance, achieving the perfect combination of elegance, comfort, service and the most impressive views of Lago Argentino and Cerro Calafate. Alto Calafate Hotel is strategically located at the entrance to the city on the way to the airport and 3.5 kilometers from downtown. Placed on a hillside, you will be able to admire the wonderful panoramic view of the lush landscapes of Patagonia.
One of the best things to do in El Calafate, today you will go on a navigation in front of the Southern wall of the amazing Perito Moreno Glacier, tour through the captivating forest and do the minitrekking over the glacier!
You will be picked up at your hotel and taken by private transfers to the Bajo de las Sombras quay (port). Here you will board a ship for a 20-minute ride to cross the arm Rico of Lake Argentino (shared service on boat). The ship arrives at a cottage where guides will divide all passengers into groups made up of around 10 people. Each group is assigned two guides, one walks at the front an another at the back.
Together wih your group and guides, you will begin a 20-minute walk towards the glacier that begins on the lake's shore and once you arrive at the edge of the ice, you wil be provided with crampons and instructions about how you should use them on the ice. The trek over the Glacier lasts about 1 hour and a half during which you will be able to see the crevasses, seracs, drains and small lakes. The walk is slow, as you walk over an uneven but firm and safe ice surface. Guides will give short talks about the flora, fauna and general glaciology facts of the region and also some information about the unique phenomenon that takes place at the Perito Moreno Glacier and eventually produces its breaking-off. When the walk ends, you will return to the cottage walking through the lush magallanic forest.
On its return to the pier the ship navigates through the channel of ice floes and then approaches the glacier's walls. You will then be able to get to the glacier's viewpoint where you will have the opportunity to walk along the pathways and admire it from different viewpoints for about one hour before returning to El Calafate.
This tour lasts approximately 5 hours (between navigation and trekking)
Recommendations:a) Age: Due to the level of effort and difficulty that it entails, this excursion is not allowed for the following: people over 65 years old, children under 10, people with overweight or some type of disability.b) Footwear: Any type of sport footwear, for example running/ tennis shoes or trekking boots. Thick woolen or cotton socks are reccommended. Rubber boots and high heels in women are not admitted. Passengers are only provided with crampons.c) Clothing: Sportive (long trousers for both sexes). It is advisable to wear a t-shirt, a sweater and a waterproof jacket/coat. Sunglasses, sunblock and gloves are also reccomended as well as a cap or a hat in case it is too cold.d) Lunch: Passengers must take their lunch boxes and only the groups which take the excursion during the morning have 40 minutes to have lunch at the cottage. Once embarked towards the Glacier, there are no purchasable products. Lunches are easily provided at most hotels, just ask them to prepare this for you.e) Smoking: It is forbidden to smoke during the excursion; neither on the boat, the forest, or the ice nor at the cottage.f) Physical state: Normal. Passengers must know that they will walk slowly for approximately three hours through varied and irregular ground such as ice, forest and stones. Pregnant women, people with heart condition or other serious health conditions are not admitted. g) Difficulty: It is easy, but relatively more complicated for elder people with vertigo or unhealthy physical conditions
Enjoy a private transfer with your own vehicle, driver and English speaking guide to Eolo Lodge.
The Hotel Los Cerros is located in El Chaltén at the foot of one of the most imposing mountains of Patagonia. Its large windows allow you to enjoy panoramic views of the valleys, lakes and mountains that surround this young Patagonian town founded in 1985. The warmth of the personalised attention of the staff and the regional food of international level pleasantly surprises even the most exacting travelers. The hotel offers lodging, services and cuisine of international level. Lingering all day long in the hotel is really tempting but the rustic nature that surrounds it calls you to enjoy scores of activities in the land of the legendary Cerro Fitz Roy and the imposing Viedma glacier. The outings to the Lago del Desierto, to the base of the Fitz Roy, to the lake and to the glacier of the Cerro Torre are real musts to have a full picture of this region, where much still remains greatly undiscovered.
Enjoy a full day trekking on Cerro Torre or Fitz Roy with a Professional Trekking Guide. Enjoy lunch en route (included).
El Chalten is the "capital of hiking" in the Argentinian Patagonia, and hiking trails are abundant. The choice is yours! You can find your way around to enjoy this day hiking on your own, or just speak to you Sales Consultant if you wish to pre-book the assistance of one of our private guides to come with you.
Meet your driver for a private transfer from El Chalten to South Point in Laguna del Desierto.
Boat transfer from South Point to Aguas Arriba Lodge. (15' boat ride along the East shore of the lake). The Lodge is accessible only on foot or sailing from Punta Sur (South Point). There are two ships each with up to 6 people plus luggage, one has a small cabin the other is open. Schedules for the boat are as follow:
From South Point to Aguas Arriba Lodge:
Departure from
Arrival at the
South Point
Lodge (*)
Aguas Arriba Lodge has various hikes you can enjoy!
Following is a summary of the activities available. Some are included and others need to be booked separately. Please call us if you have any questions or wish to pre-book any activities.
TREKKING: Trekking may be enjoyed around forests, river creeks, wetlands, glaciers and fly-fishing trips. Walks circuits may vary from 1 to 8 hours. They are of low and medium difficulty and without major drops. In the longer runs you will bring a Lunch Box to enjoy along the way. In some cases, as defined by the site guide, you can combine boating with walk excursions.
The following trail options are available:
From South Point: After being transfered from El Chalten by car to South Point, you can arrive to the lodge by foot. This is a 2-3hr hike – 6 km distance. Amazing, we strongly recommend this access! It is the best way to wash off all accumulated stress; nature's embrace re-energizes the body and soothes the soul. The hint that indicates you're already close to the lodge is the scent of lunch waiting to welcome our trekkers! Luggage is transported via boat to the lodge. A snack is provided. Another option is leaving the lodge by foot, or simply hiking towards the south point during your stay. This walk can be combined with the ascent to Huemul hanging Glacier (entrance is not included, to be paid locally USD 5). Coming back to the lodge by boat can also be arranged.
North Point of Lago del Desierto and Chilean Border: North Point can be accessed on foot from the Lodge. Duration 2:30 / 3:00 pm approx. or by boat. When arriving to the gendarmerie station in North Point, you continue to Laguna Larga, where fly fishing aficionados are often spotted.
To the West: Juana Sepulveda's Pampa: A 40' walk towards the west, arriving to a mainland where an old mountain cabin remains standing and was home to Juana Sepulveda, the first pioneer to live in this area. The Rio Diablo basin is 200 mts away from Sepulvedas' Pampa; the river flows west into a beautiful valley that finishes at the Chilean Continental Ice Field. This area offers many possible hikes of different duration and difficulty. One of the most accessible treks is walking along the riverside until the Diablo Refuge-shelter.
Fitz Roy View Points: These trails begin at the doorstep of our lodge, guiding walkers into the untouched forest that surround us. Some trails begin around the lakes' shoreline and then climb up passing river creeks and marshes to higher areas where one can appreciate the magnificent views!
Hanging Glaciers: During those days when the winds are calm, we hop on to the boat and cross the lake towards the beaches that lay in front of the lodge. Walking around the river stream we begin the ascent to the Vespignani hanging glacier. A beautiful walk that offers a new perspective of this astonishing area.
FLY FISHING: *** At time of booking, please advise your sales consultant if you wish to practice fly fishing. This is another of the great attractions in Aguas Arriba Lodge. According to the wind and the state of the lake, you can reach different beaches and practice cacth & release fishing or depending on the size of the fish, you may bring it into Aguas Arriba's kitchen to enjoy as a meal! If you want to go without a guide, the only additional cost is the fishing permit which is requested from the lodge and paid on the spot. The cost for the permit is of USD 30 per person and may be pre-booked. The price is subject to change without notice. Upon request, you can also hire the services of a guide and equipment rental (at an additional charge).
Aguas Arriba Lodge is located at the Estancia Río de las Vueltas, 37 km away from El Chaltén; with 900 meters of shore along Lago del Desierto, and 700 acres of mountain ranged forests. Its construction was a true odyssey due to its remote location. Hand built out of natural wood and noble stones, its ample window sills portray the beauty of its natural surroundings: an emerald green lake, hanging glaciers, forests', and spectacular views of The Fitz Roy. Its eco-friendly construction assures to preserve nature in its pristine state. Accessing the lodge is either by boat or by foot. It is a 15 minute boat ride from the south point of the lake along its eastern margin, or a 2-3 hr hike. The trail guides you into the heart of the forest, home to centenarian trees of the Nothofagus family (Lenga, Ñire and Coihue trees). A unique experience; indulge the senses with nature, fine gourmet, and adventure!
Enjoy one of the many hikes offered at Aguas Arriba Lodge, or practice some fly fishing!
Return boat transfer from Aguas Arriba Lodge to South Point Port (15' boat ride along the East shore of the lake). Schedule from Aguas Arriba Lodge to South Point:
Arrival at South
the Lodge (*)
Meet your driver for a private transfer from South Point in Laguna del Desierto to El Chalten.
Enjoy a private transfer with your own vehicle and driver from El Chalten to El Calafate. The journey is approximately 3 hours.• please note that the driver will speak little or no English. English speaking drivares are sometimes available at an additional cost.
Fly from El Calafate to Buenos Aires domestic airport. Flights are subject to changes based on availability. The flight duration is approximately 3 hour. An airport tax of $25- $40 pp is not included in the ticket and must be paid in the airport upon departure.
Enjoy time at leisure to explore at your own pace, or relax at your hotel.
South America
Laura Iyer ,
January 10, 2014
We just returned last night from our Patagonia adventure and wanted to tell you we had the time of our lives! Everything turned out perfectly. Guides were fun, on time and informative. The excursions were great for an active family and, of course, amazing.
I can't tell you what was our favorite. The boys enjoyed exploring the mountains in El Chalten (they called it Mountain running) while Mohan and I relaxed in the beautiful hotel. I thought after the glacier trek it can't get any better - but it kept surprising me and amazing me. My personal favorite was the horseback riding. I thought afterwards after everything we have seen the bike tour would have to be a let down - NOPE - it also was so exciting and our guide was a hoot! We had great weather for each activity (I know there is a bit of luck involved with that one).
Meals were amazing and after so many active excursions no guilt in pigging out.
I am so happy we took a little risk and went out of the way with our vacation this year. We will have this with us for a life time.
Thank you again,
Laura, Mohan, Ryan, and Nathan
South America
Catherine Dudley ,
January 10, 2014
"Hi Brandi,
GREAT trip! We were very pleased with every aspect that you set up for us including the tour of Quito and environs. Our guide spoke excellent English, the driver was courteous and we felt safe and well-informed throughout the day. We're still going through the 500+ photos that I took and the 1700+ photos that my son took. Galapagos was a fabulous trip and the Eclipse was a terrific way to navigate the islands.
Thanks again!
South America
Mark Dornfeld ,
November 11, 2013
"My wife and I had a wonderful trip, we really enjoyed ourselves. All the accommodations that you booked for us were exceptional and our drivers and guides were lovely. We had great weather the whole trip and only lost one activity due to high winds. As you know this is a beautiful part of the world so my camera was snapping all the time. We would definitely use your services in the future for this type of travel. Thanks for all you help and expertise........be well.....m.d."
South America
Jack Gregory ,
November 11, 2013
"Dear Sofia
I wanted to give you a little feedback on our recent trip to Peru.
In a word – EXCELLENT – especially the high quality people you work with in Peru. We have taken tours all over the world, S. Africa, France, England, Vietnam, China to name just a few, and the service we received in Peru was far beyond and of the other experiences we have had. The attention to detail was very much appreciated, picking us up at the airport, taking us back to the airport and complete, hassle free, handling of all our details truly made this a stress free experience.
Special thanks to:
-The entire reservation system and the people I came in contact with that process...every detail accounted for
-The people that looked after us in Lima
-Andre, the young man in Cusco who faithfully phoned every night just to make sure the day went well, my wife was well and that we knew what we had to do the next day.
-The Sumaq hotel in Aquas Calientes...you can tell the level of service by the details...I watched a waitress hold a high stool for a lady to prevent her from tipping backwards as she got on the stool, the lady didn't even know the waitress did it....that's client care.
-Especially Mariela, the tour guide in Cusco...highly knowledgeable, passionate, personable and shows great care for the people she guides.
South America
Hainsworth Sherry ,
November 05, 2013
Clients were very impressed. Guides were amazing and accommodation was beyond expectations. They will definitely travel with you again and they have highly recommended Kensington Tours.
Hope I can work with you again the in the near future.
South America
Scott Parks ,
November 05, 2013
"Dear Matt
Sandy and I are back from Peru and had a wonderful time. Kensington seems to have the best contacts in each country and Peru was no exception. I wanted to take the time to give you some specific feedback on each segment of out trip.
The "Hotel B" in Lima is fantastic. It's an old house that has been turned into a small Hotel. The people are great and the location in Barranco is just what we like.
The Inkaterra Amazonica is probably the best place place to stay in the Amazon region. The rooms give a real feel of the sounds of the rain forest.
The hotels in both Cusco and Aquas Calientes were perfect with great locations. We added an additional day in Aquas Calientes which gave us three days in Machu Picchu. For us, this was well worth it and gave us the time we wanted to see all aspects of Machu Picchu. Pictures did not do justice to the site, although we got some great pictures.
The trip to see the Nasca Lines was, also, worth the time. Our guide added some side trips including lunch at a local winery which we really enjoyed. The Hotel Paracas was an unexpectedly high quality resort and a great way to end our trip.
Thanks for your help we look forward to next year
South America
June Murray ,
August 20, 2013
"Buenas Noches Brandi-
I filled out the survey but I wanted to send you a note to say thank you. Our trip was the stuff lifelong memories are made of and I mean every part of it. From our time spent in Quito, to the Safari Camp and Isla Isabela. I cannot say enough about the professionalism of the staff at our accommodations and the expertise of all our guides (most especially Tanya Helmig at the Safari Camp). We hope to go back for an extended stay.
I have attached 2 photos for you of Bart and I. I think the joy is clearly evident- thank you for making it possible.
South America
Barbara Mackey ,
July 22, 2013
"We just completed a family trip to Costa Rica, with three families traveling from different locations. All the coordination efforts were made easily and efficiently by our Kensington representative, Brandi Merchant, who was wonderful; an absolute delight to work with. All the accommodations were first class and the guides knowledgeable and very punctual. We will be using Kensington again!
South America
Cindy Thoene ,
July 22, 2013
"Hi Brandi!!
What an AMAZING trip!!!!!!!!!!!!!!!!!!
Seriously…the trip of a lifetime!
We returned late on Thursday and had out of town visitors through the weekend and we are just now unpacking and getting back to non-vacation reality.
I will share my feedback and get pictures sent to you soon.
Thanks for everything….truly a perfect trip!
South America
July 24, 2013
"Dear Nella,
Our trip was wonderful, we had a great time, wish we could have spent more time. In fact, I now know I would have spent more time in Cuzco and the Machu Picchu area.
Machu Picchu was fabulous.
Margot, our guide, and the driver, were absolutely wonderful, low key, very personable, very accommodating, really good. We didn't end up with enough time on the last morning in Cusco to finish the tour, but got a feel- of Sacsayhuman, Qengo, Koricancha. We saw Ollayantatambo, and went to Moray and Maras, and Wayra ranch which was also outstanding, on the next day, but did not do Pisac and the market. We got tired and ran out of time so cut a couple things. Louis the coordinator was good as well.
Would love to go back and learn more some time.
The coordinator in Lima was extremely nice too, and very helpful.
In fact, we loved the food, the people and everything. The Libertador Palacio , the Tambo del Inka and the Sanctuary were indeed outstanding hotels. LAN was all on time, great service.
Thank you again for all your help.
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DAN THE FAN: Nile issue underlines firepower shortage (From This Is Wiltshire)
Latest Sport News RSS Feed
DAN THE FAN: Nile issue underlines firepower shortage
3:00pm Thursday 19th December 2013 in Latest Sport News
SWINDON'S lack of a number nine came back to haunt them again last weekend as Mark Cooper's striker-less formation nearly sent the traveling fans over the edge at Bramall Lane.
When Town signed Nile Ranger in the summer, everyone knew it was a huge gamble.
There is no doubt that Nile is a Premier League striker and has all the attributes needed to play at the top level.
But because of his problems off the pitch, he's found himself in League One.
In the first few months at the County Ground it looked to be a great piece of business, with the striker playing consistently and scoring plenty of goals in the process.
But out of the eight games played since the start of November, Nile has only made three appearances, and hasn't worn the red and white oat all in December.
It's obvious and understandable that the 22-year old's mind has drifted onto his upcoming court case.
But manager Mark Cooper has stated that Ranger won't feature again for Town "until he shows the rest of the players a bit more respect".
This whole situation can not be left to gather dust over the Christmas period and into January – he is too important to our future success.
The club either has to bring him back, or sign a replacement.
With Nicky Ajose likely to leave in January, that'll leave us with Dany N'Guessan, Miles Storey and Mohamed El-Gabbas as the club's strike force going forward.
None of those three are the same type of striker, and can't play in the number nine role vacated by Ranger.
Lets hope this new link with another Premier League club, announced by chairman Lee Power last week can deliver us a new striker in early 2014.
How Town operate in the upcoming transfer window will determine whether we are fighting for a play-off place, or a mid-table finish.
With Alex Pritchard and Ajose likely to be sold by their parent clubs next month, they will have to be replaced, no excuses, ifs, or buts.
It will be Power's first big test as chairman of the club since taking over from Jed McCrory a few weeks ago.
If the Town faithful only witnesses players leaving, he could potentially lose the trust he desperately needs if he wants to be successful.
With Cooper only trusting Darren Ward and Grant Hall to play regularly at centre -back, a couple of new faces to increase competition need to come in, with Troy Archibald-Henville out for the long term.
The Town squad will play four games in 12 days from this Saturday over the hectic Christmas schedule, starting with Coventry at the County Ground this weekend.
Finally, a tribute for a good friend of mine Doug Sawyer who passed away last week. Doug (1927-2013) was one of the most genuine people I've ever met, a true man of God.
FOR MORE SPORTS NEWS, REPORTS & PICTURES SEE THURSDAY'S GAZETTE & HERALD AND FOLLOW US ON TWITTER @gazsport


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- Program update from 2014 FAA Commercial Space Transportation Conference / [Audio]
- NASA is reviewing its policy on human-tended payloads and will provide an update to this website
- Follow us on Twitter: @nasafo .:. Subscribe to our mailing list: flightopportunities-news
- Visit our flickr page at www.flickr.com/photos/nasafo/sets/
- NASA/STMD February 2014 Report on State-of-the-Art in Small Spacecraft Technology
Find out how we can help you get your hardware off the ground. We offer flight opportunities and support capability enhancement of the suborbital launch industry.
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To date we have flown 13 parabolic campaigns, performed multiple Entry, Descent and Landing (EDL) tests, launched several balloons, and two sounding rockets.
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The 138 projects currently in our Portfolio come from a wide variety of organizations, including NASA, academia and industry, both US and international.
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We started with parabolic flights in 2011 and have been bringing new vehicles online ever since. In 2014 we offer flight testing in various relevant environments.
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Classical music and opera
Your guide to classical music, concerts and opera in London
- Classical concerts this April
- Clean Bandit's top classical venues
- Fflur Wyn interview
- Andrew Smith interview
- Steve Reich interview
Read our opera and classical interviews
Classical venues in London
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Cedar Doors: Magi Before Herod?
Detail of the Cedar Doors, which despite their name are carved of pine. These splendid doors from the mid-12th-century show strong Arab influence, which would have been derived both from contact with Muslim Spain and the Crusades. The left door is carved with reliefs of the Nativity of Christ; the right door depicts the Passion of Christ. The reliefs are surrounded by mock Kufic script and Latin inscriptions in a similar style.


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Michael Pena Gossip
Michael Pena gossip, latest news, photos, and video including career, style, roles, awards, relationships and other news
Michael Pena loves Xenu?
August 26, 2013 16:52:22 Posted at August 26, 2013 16:52:22 Photos:
Handout/ Getty
Handout/ Getty
Xenu had a birthday party the other day. It was the 44th anniversary of the Celebrity Scientology Centre and most of the notables who haven't been excommunicated where there including the usuals – John Travolta, Kelly Preston, Jenna Elfman, and …Michael Pena? Where the f-ck have I been? I love Michael Pena! Michael Pena loves Xenu? Michael Pena is in End Of Watch, one of my Top 10 movies of 2012 Full Story


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Farm Invasion USA - Premium
10,000 - 50,000 downloads
- Fun, original
- Excellent graphics
- Enjoyable gameplay
- Addictive
- Didn't find any. Did you?
"The invasion of the corns"
Reviewed by Anna Grace / Jan 10, 2013
Original action-full gameplay, really exciting and enjoyable
Farm Invasion USA is an action game in which Aliens have invaded the States and they want your corn,so you need to defend your fields and so you should kill all the aliens you can while harvesting the fields and collecting as many items as you can; some of which will even give you a boost.
Also, you should try to avoid collisions, as they will make you lose power and eventually lose. At the end of the day, you will receive your payment and you'll be able to purchase items that will help you increase your score in the game.
What could be a really simple game turned out to be something really enjoyable, an impressive action game that is really addictive, with smooth graphics and a long story line that keeps you playing. A lot of features are presented and they make the game really complete and enjoyable. HandyGames is the developer of Farm Invasion USA, a really good game for all players. We haven't found anything we didn't like so we can only give it the highest score.
***** Crazy cool runner game!
***** Awesome fun shooter!
* Play without ads and start with 2750 Popcorn! *
✔ Spaced out runner game featuring rednecks and aliens
✔ Powerful upgrades for your jury-rigged weapons
✔ Tons of tuning parts for your deadly harvester
✔ Collectable alien technology for cool power boosts
✔ Diary entries to enjoy the whole story
✔ Dozens achievements and challenges for endless fun
✔ Full tablet support
✔ Controller support
* Supports Google Play game services *
* Optimized for big screen TV over MHL *
* Supports Immersion haptic technology *
UFO sightings at old Pops' farm! Use a huge arsenal of insane weapons to keep the aliens from stealing the corn harvest. Hop on your corn chopper and mow down every single last of the little blue invaders! Neither armed spaceships nor dangerous obstacles will stop you from becoming the world's greatest alien hunter-killer! Dodge alien tractor beams and face the dreadful all-devouring martian trolls in your heroic defense of old Pops' corn farm!
Help Pops, Joe and Otis to defeat the corn-grubbing monsters from outer space!
You can play Farm Invasion USA entirely for FREE, though various items are available via in-app purchase. If you don't want to use in-app purchases, please deactivate them in your device settings
Thank you for playing 'Farm Invasion USA'! Check news and give feedback on:
Thanks for all your feedback! Here's what's new in this version:
- Fixed crash in the diary menu
- Fixed crash when beating a friend's high score
- Support for non touch screen devices added
- Added controller support!
- Shop rework
- x86 support
- Added support for Google Play game services. Sign in with your Google+ account to access online leaderboards and achievements.
- Added screenshot save and share functionality
- Added Immersion haptic technology
Some lists where this application appears: Reviewed by Anna Grace.
Fun game but some of the in app purchases cost as much as 50 and 100 REAL dollars for one item. OUTRAGEOUS!!
I cannot update it uninstalled cannot reinstall
A casual game with high level of fun factor... Enjoyed a lot..
Good responsive game play and the only annoying thing for me is the upgrade weapon ads after every play.
Very imaginative fun game
Still getting ads!


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My TOTO Carlyle CST874 (MS874114SG) wouldn't stop running so I lifted the lid and then bent down to shut off the water at the wall. I knocked off the lid and it shattered. What's the best place to buy a replacement? Online? Nearest plumbing supply (none local)?
I also need to replace one of the screws that holds on the seat. We had Totos in our previous home for 12 years and the seats never wobbled or came loose. In this home, the seats on both toilets would loosen and have to be tightened regularly. (Doesn't everyone keep an old kitchen knife under the bathroom sink?) One of the screws is apparently stripped as it spins and won't tighten, so I need to find a replacement for this part, too.


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If you have already taken that pumpkin patch picture or plan on doing it tomorrow, then make sure to take advantage of this freebie from Walgreens. Through tomorrow, you can get a free 8 x 10 enlargement... And make sure to have in-store pick up because that's free too. But the last day to do that is tomorrow.
The Mitchell Lake Audubon Center is hosting it's Fall Wildlife Festival and Plant Sale where there will be some free stuff given away. C-P-S Energy will have a tree giveaway, SAWS will be doing an Autumn Bloom Giveaway and Steve Browne told us yesterday that Dr. Calvin Finch will be out there giving away crawford lettuce. That's tomorrow from 9 a.m. to 3 p.m. at the Mitchell Lake Audubon Center on Pleasanton Road.
Monday is a special day at Maggiano's Little Italy. They are hosting "National On the House Classic Pasta Day." That means if you eat there on Monday night, you will get to go home with one of their classic pasta dishes for free.
And a couple of reminders:
For the whole month of October, Cream of Wheat is giving you the chance to try it's new flavor: Chocolate! Everyday on their Facebook page, they are giving away 10-thousand samples of the product. But you have to act fast because they will run out.
And here's a great freebie for all breast cancer survivors: Salons at J.C. Penney are giving free haircuts to survivors in the month of October. And for the first 50-thousand free haircuts, J.C. Penney will donate one dollar for each haircut to breast cancer research. But you will need to make an appointment.
Outback Steakhouse is offering up some free wings. Every Thursday through November 8th, you can add a half order of wings to any meal by telling your server to "wing it" when you place your order.


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Technical Papers and Presentations
Improving Fuel Usage in Microchannel Based Fuel Cells
P. Fodor, and J. D'Alessandro
Dept. of Physics
Cleveland State University
Cleveland, OH
In this work a miniaturized fuel cell design based on microchannels, into which the liquid fuel and oxidizer streams are fed through T shaped connectors, is optimized for improved fuel usage. This particular design exploits the laminar nature of the fluid flow at small Reynolds numbers to keep the fuel and oxidizer confined in the vicinity of the corresponding electrodes without the need of a ...
Optimization of the Lithium Insertion Cell with Silicon Negative Electrode for Automotive Applications
R. Chandrasekaran, and A. Drews
Research and Advanced Engineering
Ford Motor Company
Dearborn, MI
The US Advanced Battery Consortium (USABC) has established goals for long term commercialization of advanced batteries for electric vehicle applications. In this work, a dual lithium-ion insertion cell with silicon as the negative electrode and an intercalation material as the positive electrode is modeled using COMSOL Multiphysics. Both are composite porous electrodes with binder, void volume ...
Simulating Performance and Species Crossover in a Vanadium Redox Flow Battery using COMSOL Multiphysics
E. Agar, K. Knehr, C. Dennison, and E. Kumbur
Electrochemical Energy Systems Lab.
Dept. of Mechanical Eng. and Mechanics
Drexel University
Philadelphia, PA
Vanadium redox flow batteries (VRBs) are a promising new energy storage technology designed for use in long term applications such as uninterruptible power supply and coupling with renewable energy sources (i.e. wind and solar). Crossover is the undesired transport of vanadium ions through the ion exchange membrane during operation and is a major factor limiting the overall efficiency and ...
Modeling Simulated Concrete Durability Problems with Double Layer Theory
H. Bernardes[1], M. Mancio[2], and P. Monteiro[3]
[1]Sao Paulo State University - UNESP, Ilha Solteira, SP, Brazil
[2]Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil
[3]University of California, Berkeley, CA, USA
According to the Gouy-Chapman theory, a double layer structure appears on the surface of a solid particle, a gas bubble, a liquid droplet, or a porous body when it is placed into a liquid. In this work, a one-dimensional model of the electrochemical reactions has been developed in the COMSOL Multiphysics environment. The model accounts for solution chemistry, cell potential, and solves the ...
Simulation of Cyclic Voltammetry of Ferrocyanide/Ferricyanide Redox Reaction in the EQCM Sensor
H. Kwon, and E. Akyiano
Dept. of Engineering and Computer Science
Andrews University
Berrien Springs, MI
In this paper, the cyclic voltammetry behavior of Ferrocyanide/Ferricyanide, which is commonly used for electrochemical DNA detection experiment, was studied in the commercial EQCM-D setup (Q-sense) using the COMSOL Multiphysics. The model was established in a 3D geometry of QCM liquid cell. The simulation shows depletion of concentration of ferrocyanice following applied electrode potential. ...
A 2D Axisymmetric Electrodeposition Model
R. Pryor
Pryor Knowledge Systems, Inc.
Bloomfield Hills, MI
Electroplating is a vital technology widely employed for many technological applications ranging from decorative or anti-corrosion coatings to high precision nanotechnology passive electromagnetic cloaking devices. This 2D Axisymmetric Electroplating Model demonstrates one of the modeling methodologies that can be used to calculate the transient generation of a coating thickness of a deposited ...
Effect of Channel Width on Fuel Cell Performance Using 3D Modelling
R. Pushpangadan, S. S. Dimble, and S. P. Duttagupta
IIT Bombay
Maharasthra, India
A three Dimensional model of the PEM Fuel cell is implemented using COMSOL Multiphysics and the channel width is varied to study the performance.Effect of channel width on the performance of the cell is studied by varying the width of the channel and keeping channel width to rib ratio constant at 1. Rib width is the width of the GDL area which is not covered by the channel. All other parameters ...
Using Computational Multiphysics to Optimise Channel Design for a Novel PEM Fuel Cell Stack
F. A. Daniels[1], D. J. L. Brett[1], A. R. Kucernak[2], and C. Attingre[2]
[1]University College London, London, UK
[2]Imperial College London, London, UK
Polymer electrolyte membrane (PEM) fuel cells have significant potential as a source of clean, efficient energy production. This study presents a three-dimensional, non-isothermal, fully-coupled model of a PEM fuel cell with printed circuit board current collectors. The effect of the current collector design on transport phenomena and consequent cell performance is investigated. The model ...
Fluid Flow and Current Density Distribution in Large-area HT PEMFCs
G. C. Bandlamudi[1,2], C. Siegel[2], C. Heßke[1], and A. Heinzel[1,2]
[1]ZBT Duisburg, Duisburg, Germany
[2]University of Duisburg-Essen, Duisburg, Germany
High temperature polymer electrolyte membrane fuel cells (HT PEMFCs) are very promising technologies when used in combined cooling and heating power (CCHP) systems. They are operated at 160°C, offering the possibility of high tolerance to fuel impurities and a possibility to use the heat generated for cooling and heating purposes, leading to higher total system efficiency. Employing a ...
Development of Tiny Fuel Cells for Micro-devices on the Basis of Simulation Results
S. Tominaka
International Center for Materials Nanoarchitectonics
National Institute for Materials Science
For the successful exploitation of microdevices such as microsensors, development of micro-power sources is strongly required. In this view, microbatteries and microfuel cells have been developed. Here the concept of on-chip fuel cells, which consist of all the components necessary for power generation integrated on a chip, is introduced. Then, in order to improve their performance, experimental ...


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All in a Day | Jan 15, 2013 | 13:32
Canada's response to Mali
Today Canada sent a C-17 transport plane to Mali for non-combat help. We asked a military expert and the head of an NGO working in the area for their thoughts on what's needed most in Mali.


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Stocks for the Long Term: Why Prospects Are Rosy
by Dale Domian and William Reichenstein
You already know the bad news: U.S. stocks as measured by the S&P 500 lost almost 50% from the October 2007 peak though November 18, 2008. Most foreign stock indexes were off by a little more than 50% this year.
The good news is that based on today's depressed prices, long-term stock prospects appear above average.
In this article, we take a look at some of the evidence that supports a rosy multi-year stock outlook, and provide a framework for applying these forecasts.
...To continue reading this article you must be registered with AAII.
Already registered with AAII? Login to read the rest of this article.
to read this article and receive access to future AAII.com articles.
William Reichenstein , CFA, holds the Pat and Thomas R. Powers Chair in Investment Management at Baylor University and is head of research at Social Security Solutions, Inc .
Donald from Maryland posted over 3 years ago:
Will AAII be publishing the three indicators discussed in this article?
Joesph from Pennsylvania posted over 3 years ago:
I am a relatively new member to aaii. Still exploring and learning from the writings and all that the web site has to offer.
Same question as above. Will aaii be publishing the 3 indicators discussed in the article each quarter? Or, will aaii direct readers as to how we can review a summary of the selected tables/charts with the data offered?
Charles Rotblut from Illinois posted over 3 years ago:
These indicators are not included the datafeeds we receive. Robert Shiller maintains a website with his information at http://www.econ.yale.edu/~shiller/data.htm
The bond yields are available at many financial websites, such as Bloomberg.
I would check Value Line's website for its indicator.


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With a flu epidemic affecting much of the country, local hospitals are hoping to protect their patients by keeping visits to a minimum.
Mount Auburn Hospital website is limiting people who can visit the post-partum unit (mothers and babies) to help limit the spread of the flu virus:
Influenza Illness Screening Tool It is routine policy to restrict visitors to Post-Partum (Mother Baby Unit) who have symptoms of communicable disease. Given the current outbreak of influenza in the community, ALL visitors shall be actively screened for the presence of influenza like illness. If any of the symptoms below are present (or were present within the last 24 hours), that person should not be allowed to visit N5/ST5.
- Do you have a fever (100°F or greater)? A fever occurs when your body temperature increases in response to illness or injury. Your temperature is considered elevated when it is 100°F or greater.
- Do you have dry cough, sore throat, or nasal congestion/runny nose? One or more of these symptoms is usually present with any upper respiratory infection including influenza
- Do you have muscle aches? Body aches that are sudden and unexplained can be a sign of the flu.
- Do you have chills? Body chills not related to a cold environment can be a sign of the flu.
Similar restrictions have been put in place at the Newton-Wellesley Hospital, according to the hospital's website. The visitor limitations include:
- For medical or surgical patients - two visitors per patient at a time
- Maternity patients - Parents plus two visitors per patient at a time
- No visitors under the age of 12
- If you have the flu or flu-like symptoms (fever, cough, sore throat, runny nose), do not visit a patient
- If you have not had a flu shot, do not visit a patient
Flu shots are available at the Mount Auburn Hospital walk-in center. Also, the Watertown Health Department is holding a flu clinic on Friday afternoon. See details here.
For more information on how to prevent the flu, check out these tips from the CDC.


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Thanks Cora, you've made my day. I'm loving that I make you smile. You got me smiling that you are smiling. Let's all keep smiling, we feel better, we treat each other better, it's a better world when we smile and LET LOVE RULE!!!! Yaaay!!!!!!!!!
Love museums, sports, dancing, laughing and just about all genres of music


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See Details
-Barcelona, Spain
-Saint-Tropez, France
-Cannes, France
-Portofino, Italy
-Rome (Civitavecchia), Italy
-Sorrento/Capri, Italy
-Messina (Sicily), Italy
-Corfu, Greece
-Dubrovnik, Croatia
-Venice, Italy
-Koper, Slovenia
-Split, Croatia
-Kotor, Montenegro
-Amalfi/Positano, Italy
Explore glamorous ultra-fashionable Cannes, with its majestic hotels, millionaires, movie stars, and mega-yachts in a gem-like setting along the sparkling Mediterranean. Stroll along the Royal Palm tree lined Boulevard de la Croisette where world-renowned designers cater to the rich and famous. Look for haute couture and antiques. Enjoy a cocktail in one of the grand hotels. Take lunch in a fashionable café on the boulevard. Visit the gardens and parks sprinkled along the boulevard. Hike up the hill to Le Suquet, the medieval old town. Enjoy a coffee at an outdoor café with expansive and exquisite views of the harbor.
The following Shore Excursions are available for this port on this cruise, and may be reserved beginning 240 days before the cruise begins for guests receiving Concierge amenities, and 180 days before the cruise begins for all other guests. Guests receiving Concierge amenities will receive a 5% discount off of the prices shown below for Regent Choice tours.
Travel to the fabled Principality of Monaco on this full-day tour that showcases one of the jewels of the French Riviera.
Boarding your coach at the pier, you will first travel to Nice where your route takes you along the famous Promenade des Anglais before continuing to the Principality of Monaco via the Middle Corniche. During your drive you will be treated to marvelous scenic views of Villefranche, Cap Ferrat and Beaulieu. Your route also takes you past the medieval village of Eze, which sits perched on a craggy peak overlooking the Mediterranean.
Arriving in the Principality of Monaco, your coach will park at the foot of the rock of Monaco and together with your guide you will walk to the escalators that bring you to the top. Once on the upper level, you will commence a guided walking tour that passes by the Oceanographic Museum, the Cathedral and allow you to view the exterior of the Prince's Palace. At mid-day, you will have the added enjoyment of observing the changing of the guards in front of the Prince's Palace.
Following lunch at a local restaurant, your tour resumes with a walk to the well-known Grand Casino (visit not included) and then you will have a bit of free time to take in the attractions of your choice around the Place du Casino. You may wish to stroll across the street to admire the Hotel de Paris, do a little window shopping around the corner, or perhaps try your luck at the Café de Paris Casino.
All too soon it's time to make your way back to your coach for the return journey to Cannes and your waiting ship.
Please note: This tour includes approximately 2 1/2 hours of walking and there are several steps to negotiate. Guests must take an escalator and/or elevator from the parking area at the Rock of Monaco. The tour is not available to wheelchair guests and not considered suitable for those with mobility concerns. Conservative attire is required when visiting any cathedrals or casinos and shoulders and knees must be covered. No short pants, shorts or tank tops are permitted. Flat, comfortable walking shoes, a hat, sunglasses and sun screen are suggested. The Casino opens at 2:00 p.m. and no one under the age of 18 is allowed inside. A passport is required to enter the Casino.
Terms & Conditions:
Free Unlimited Shore Excursions are for full fare guests only, capacity controlled and subject to availability. Requested excursions may not be available at time of booking. Supplement will apply on Regent Choice excursions (indicated by the above) and excludes Private Arrangements and all Adventures Ashore programs. In order to ensure quality guides and sufficient transportation, we must provide the tour operator with passenger counts at least 36 hours in advance. Therefore no refunds will be given within 36 hours of tour departure for cancellations or no-shows. Please pay special attention to scheduling and tour lengths when booking your shore excursions. In many cases, it is not possible to participate in more than one tour per day in a given port. Tour Departure times are subject to change so please reference your actual tour ticket for the correct departure time. Tours operate rain or shine. Minor children under 18 years of age must be accompanied by a an adult parent or guardian on all shore excursions. Tours require minimum participation levels to operate so please sign up as early as possible. Tours may be cancelled if minimum participation levels are not met. Prices, Itineraries and General Information shore excursion prices are subject to change to meet unexpected cost increases or currency fluctuations. Please consult the Destination Services Desk onboard for information. During local or national holidays, access to certain facilities (such as museums or archaeological sites) may be limited or denied. In such instances, adjustments will be made to minimize inconvenience to guests. Some tours have limited availability. Tours are generally available for reserving 180 days prior to the beginning of a cruise. Please sign up early to avoid disappointment. Regent Seven Seas Cruises reserves the right to require guests to complete a liability waiver for select shore excursions. For more information, please visit the Destination Services Desk onboard.
Please have a preferred travel agency partner contact me about this cruise.
Remember my preference.
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In my neighborhood, Lake Farm Metropark's haunted hayride had become a rite of passage for the five little boys who lived next door. Each one had to be old enough to not get "too" scared to go.
In the spirit of the season, we've put together a list of where you can enjoy hayrides -- family friendly and scary -- in Northeast Ohio.
Have we missed yours? Email Patch Regional Editor Susan Patton and we'll add it to the list.
And if you take any photos of your family or scary monsters at a hay ride, share it on this post!
Cuyahoga County
FAMILY FRIENDLY: At the Chalet Recreation Area in Cleveland Metroparks' Mill Stream Run Reservation in Strongsville, tractor-drawn hayrides are offered October Saturday nights (Oct. 13, 20 and 27) from 6 to 10 p.m. and Sunday afternoons (Oct. 7, 14, 21 and 28) from 1 to 4 p.m.
FAMILY FRIENDLY: on Meadows Drive between Parkview and Valley Parkway in Brecksville, is hosting a horse-drawn wagon hay ride 1-4 p.m. Oct. 21. Admission $10, children under 6 are free.
Summit County
FAMILY FRIENDLY: In Akron at the you can get a little of everything. Starts today and continues Oct 14, 20 & 21, 27 & 28 from 10am-4pm at Graf Grower's Garden Center, 1015 White Pond Dr, Akron.
FAMILY FRIENDLY: Hay Rides every weeekend in October, noon to 5:30 p.m. at the .
HAUNTED HAYRIDE: Every Saturday night in October, 8-11 p.m. at Heritage Farms, 6050 Riverview Road, Peninsula, there is a haunted hayride. "Come if you dare to be scared" they say on their website. Admission $13.
Visit the Bath Nature Preserve from 11 to 3 p.m. on Oct. 13 for fun fall activities. Live band, corn hole tournament, hay rides, face painting and much more at this Bath Township event.
Lake County
HAUNTED HAYRIDE: The haunted hayride at Lake Farm Metropark in Kirtland is our family's favorite. But you have to buy tickets way far in advance. Unfortunately, they are already sold out. :( If you want to go next year, start looking for information in early September.
Lorain County
FAMILY FRIENDLY: At Pickering Hill Farms, Saturdays and Sundays from 12 until 5, kids can get a free hayride through their 2-acre pumpkin patch.
HAUNTED HAYRIDE: At the Spooky Ranch at Rockin-R-Ranch, 19066 E. River Rd., Columbia Station, they specialize in scary. Check out the haunted hayride through a forest of fear. They are open all month, but check out hours and dates here. You can buy tickets online or at the gate. But it's worth checking out their website. Caution -- there's spooky music that automatically plays.


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#91: Policy&CommissionsI'm so mad!
Well people, it's time to clarify some questions. Now I'm serious.
Can I use this image as wallpaper?
Yes, you can, as long as you don't modify it and it's for personal use.
Can I use you work to build up another one of mine?
No, you can't. I spend a lot of time to make my images, and I will be glad if they stay as they are originally.
There have been some people asking me after they did the work. At least ask me before!
Next time I'll find a derivative work, I'll report it to deviantArt.
My work IS NOT STOCK!!!
Can I use your piece as cover of my literature?
You can, as long as you credit me in the description (or wherever you want) and the image isn't modified.
Can I use your piece to make a video?
Same as the previous point.
Can I share your piece?
Sharing is encouraged. You can share my pieces (only if you want,
#89: Frequently Asked QuestionsOk guys, I think it's time to do a little FAQ, because I read the same questions over and over.
Let me see if it's useful for somebody.
OMG, what is this?
It's a fractal, baby!
What is a fractal?
It's a really difficult question to answer, but I'll try to keep it as simple as I can. So, fellow fractalists, if you're reading, I won't be that precise in answering.
Wikipedia says: "A fractal is a mathematical set that has a fractal dimension that usually exceeds its topological dimension and may fall between the integers."
Wait, what? I didn't even understand myself.
Ok, a fractal is basically the repetition of a same "image". This image can be repeated with its original dimension or fractal dimension (it can be resized).
For example, let's pick the Romanesco Broccoli (the image is from Wikipedia):
As you can see, it's a repetition of the same "peaks" over and over, each of them with diffe
#88: The Great Mandelbulber - dark-beamHello people, and welcome to the first of a (I hope) long series of interviews to Mandelbulb 3D artists!
First of all, I need to spend two words on the title: I know that there's another fractal program called Mandelbulber, which is different from Mandelbulb 3D, but the other alternative was to give the name of Mandelicious!, which sounds too stupid to me. I have difficulties in naming my fractals, let alone these things.
I studied a bit on what kind of question I could ask, and I have to thank all those people who make interviews here on dA (exspecially those I watch ). They inspired me a lot!
(yeah, some questions are pretty much the same )
dark-beam kindly accepted to be the first. :iconteheplz: He's a really nice fellow deviant, other than being the author of many MB3D's formulas.
The Great Mandelbulber - dark-beam
Hello dark-beam! Tell us something about you.
I'm an Engineering stu
#100: The Great Mandelbulber - MarkJayBeeThe 100th issue of my journal and there's nothing better than a Great Mandelbulber to fill it!
Good morning people! Welcome to the second volume of The Great Mandelbulber, a series of interviews to discover the Mandelbulb3D world with the eyes of artists who use it.
The wait is finally over, here it is the interview with MarkJayBee! Please, have some time to read it, you won't regret!
The Great Mandelbulber - MarkJayBee
Hello MarkJayBee! Tell us some about you.
I live in the small seaside town of Largs, on the west coast of Scotland, which has some wonderful scenery and sea views. As a visual artist and photographer, living in this location has always acted as a great source of inspiration for me, and I count myself very fortunate to live here.
I've been producing artwork in one form or another for as long as I can remember and that goes back quite a long while!! My influences mainly stem from Science F
#114: The Great Mandelbulber - bib993Hello people, welcome to the third interview of The Great Mandelbulber series!
Today I'm gonna introduce you Jérémie Brunet, better known as bib993!
Everybody knows Jérémie for his outstanding Mandelbulbs, which have been part of many shows, as the recent Beyond The Infinite exibition in Karlstad (Sweden) along with MANDELWERK:
Definetely a great example to follow!
Let's go straight to the interview!
The Great Mandelbulber - bib993
Hello bib993! Tell us something about you.
I bought 2 high end PCs in last 2 years just to make fractals!
Was Mandelbulb 3D your first choice when you began your artistic journey?
To be honest, I never intended to begin any artistic journey! Like many fractalers I'm just a kind of lazy geek who likes to produce stunning graphics in a few mouse clicks.
To answer your question, I don't remember exactly the first programs I used t
#127: The Great Mandelbulber - GrahamSymGood morning! It's the 14th of the month, that is to say time to introduce another master of MB3D!
We had a trip in Europe: we went to Italy, then in Scotland, to end in France. It's time to go back to the United Kingdom and pay a visit to GrahamSym, the master of sci-fi fractals!
Well, in my opinion! But I'm sure many of you will agree with me.
The Great Mandelbulber - GrahamSym
Hello GrahamSym! Tell us something about you.
I live in East London, married 3 grown up children. I worked as a Museum technician, until ill health forced me to retire. I play guitar and bass. In the 80's and 90's I played in bands but it took too much comittment once my children were born, although I still have the odd jam with friends. I have been creating computer art of one sort or another since the late 90's. I used Terragen, Truespace, Blender, Bryce, Photoshop and a few others.
When did you start making fractals? I
#139: The Great Mandelbulber - EvgeniaGolovchenkoHello!!! Sorry for my lack of activity, anyway I can't miss to make an entry for The Great Mandelbulber!!!
We hit the 5th issue, so let's celebrate it with Evgenia Katya Lyubeznaya-Golovchenko, better known as ArtisticLicenseNow!
One of my favourites, for her incredible surreal scenery to her polls (check them out!).
The Great Mandelbulber - ArtisticLicenseNow
Hello ArtisticLicenseNow! Tell us something about you.
Going back, I studied art in college, but wanted to study more academics much to the dismay of my art professors. Then Maths and Languages professors were dismayed at my will to still study art. I've been at odds ever since. As many will attest. I like changing my name on deviantart, wish I could change it every 2 weeks. Favorite colors are the greens, golds, oranges and turquoises. Favorite combination is green, black and white. It has to be the right green tho. Very, very hard to find.


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Thank you again for one of the fastest and smoothest transactions ever. If anyone is looking to buy a watch from you, they have definitely come to the right place. In my humble opinion they need not shop anywhere else.
The Prices and Service are second to none."
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text: In Green Bay, Wisconsin, the NBC affiliate had a little fun with the replacement referee situation. They called in a replacement weather man to show that sometimes you need the experts to handle the tough jobs. Of course, now that a compromise has been reached, the official NFL refs are back on the job.


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posted by Colm Hanratty | 0 Comments
Mika Hakkinen, the ex-Forumla One Driver from Finland, has been spotted at a campsite in Italy with his family!
One time champion of the elusive Formula One championship (he won it in 1998 and again in 1999) recently stayed at Plus Camping Jolly located on the outskirts of Venice. While he didn't actually stay in one of the campsite's own cabins, Mika and his familiy instead stayed in his very own 13-metre long mobile home.
Mika stayed at the campsite for a couple of days and staff said he was very friendly and making jokes with them all the time (here he is at the campsite).
While he may not be driving his speedy motor any more, and earning lots of money, we reckon he still has some money from his earnings resting in the bank. So who says hostels and campsites are strictly for budget travellers?
In our hostelworld.com travel blog we bring you all the latest company news and information on new additions to the site including podcasts, videos and more. You'll also get inside information on a variety of destinations across the globe as they're visited by our travel editor and writers.
Charlotte said
Sherry said
Juliana Roes said
" Soul Kitchen Junior - Saint Petersburg, Russia. The best ever!
Andy said
Manuela Ferrer said


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October 28, 2009
Interventional Radiologists perform a new procedure that can relieve crippling back pain for some patients. The procedure is called Balloon Kyphoplasty {KIE-FO-PLASTY} and doctors at Martha Jefferson Hospital have performed nearly 500 of them. The surgery is usually done on older patients who are living with osteoporosis or weakened bones.
"They usually break really with minimal trauma, as little as going over a bump in a car or just a very minor fall, because their bones are week," said Dr. Anthony Spinelli.
That break can be fixed with the Balloon Kyphoplasty procedure. Despite the big name, it's really a small outpatient surgery to repair the fracture. When the bone breaks, it compresses the vertebrae so it is shaped more like a wedge instead of a cube.
"We place two needles into the fractured vertebral body and through these needles we put two balloons. These balloons we gently inflate together and what that does is it gets the vertebral body that's broken wedge configuration back up to its normal configuration. We then remove the balloons and introduce bone cement that goes into that cavity we created. The cement stabilizes that vertebral body," said Dr. Spinelli.
The balloon surgery decreases the pain from the fracture, and Dr. Spinelli says the complication rate from this procedure is less than one percent.
"The bottom line is it's an extremely safe procedure. It's minimally invasive and patients who have severe wedge compression fractures with significant pain, the benefit far outweigh the risk," he said.
If you are thinking seriously about Balloon Kyphoplasty as an option to cope with your back pain, the Intervention Radiologists at Martha Jefferson Hospital say there are other procedures, but Kyphoplasty is their choice to fight this costly and painful problem.
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Georgia Regents Medical Center is the only hospital in the Southeast offering da Vinci robotic surgery for thyroid nodules. The procedure, which eliminates neck scars, is performed by David Terris, MD, an otolaryngologist with Georgia Regents Medical Center's Thyroid and Parathyroid Center. The only center of its kind in the area, it staffs an endocrinologist, surgeon and radiologist who work as a team to provide multidisciplinary, coordinated care for patients with problems of the thyroid and parathyroid.
What are Thyroid Nodules?
Thyroid nodules are lumps that form within your thyroid, a small gland at the base of the neck, just below the Adam's apple. They are more common in women, and the risk increases with age.
"The nodules are generally discovered during routine exams, and rarely cause symptoms," says Dr. Terris. "Occasionally, nodules become so large you can feel them and see swelling at the base of the neck. If you find nodules, consult an endocrinologist. He or she will perform a biopsy to determine if your nodules are benign or malignant."
If the test results are suspicious or indicate cancer, or if the nodules are pressing on the throat or creating anxiety, you may need a thyroidectomy, a surgery to remove the nodules and all or part of the thyroid gland.
Georgia Regents Medical Center Offers Advanced Robotic Thyroidectomy
Traditional thyroidectomies require hospitalization and a 3-4 inch incision in the neck, which causes scarring. The robotic procedure, on the other hand, can be performed through a small incision under the armpit or in another remote location, to avoid visible scarring.
"The system's true 3-D visualization also delivers clearer images, and its instrumentation allows for increased precision, facilitating outcomes," Dr. Terris says. "The surgery may be right for motivated patients who want to avoid scarring."
To schedule an appointment with an Georgia Regents Medical Center Otolaryngolgist, please call 706-721-CARE (2273) or request an appointment online.
More information about Head and Neck surgery.


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2500 Griffin Rd, Fort Lauderdale
Excellent. The food, the people, the service. They ever know how to properly cook my steak 'Pittsburgh". We celebrated my parent's 40th anniversary there way back in 1990 and they…
128 S Federal Hwy, Dania
In short, Jaxson's is a tourist trap. The best part of this place is its atmosphere. People who like this place must mistake quantity for quality. The nicest staff members that…
1815 Griffin Rd, Dania
In ShortOperating since 1960, Domino's is best known for its delivery service and pizzas arrive hot, thanks to the company's plugged-in HeatWave delivery-bag technology. Build your…
1300 S Federal Hwy, Dania
In ShortKid-friendly eat-in restaurants and small takeout shops alike sport interiors done in the signature red and white with a touch of yellow. Orders are placed at the…
300 Gulf Stream Way, Dania
In ShortSubway's health-conscious menu is built around greaseless deli sandwiches--turkey, chicken, roast beef, etc.--made on soft rolls baked daily in-house. Customers pick white,…
4261 Griffin Rd, Davie
So many kids games there. I almost forgot I was in a bar! The whole front end is full of kids games that should belong in McDonalds or Burger King, not a local…
1317 South Federal Highway, Dania Beach
If you want a great raw bar in South Florida, this is the only place to go!
3801 Griffin Rd, Fort Lauderdale
We entered the restaurant 20 minutes before the lunch buffet closed at 3 pm. The restaurant only had like 4 tables filled with customers. As we came in we were told to just go in…
2990 Griffin Rd, Fort Lauderdale
I loved this service!!!! I receive my food fast and hot! i order from them at least 3 times a week! I highly recommend it =)
201 S Federal Hwy, Dania
In ShortThe first International House of Pancakes opened in a suburb of Los Angeles in 1958 serving a menu of hearty breakfast favorites. Today the restaurant still serves its…


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Still recovering from last week's distressing Frontline revelations of how life ends for cancer patients in the intensive care units of New York, I feel enormous gratitude to Elizabeth Edwards for showing us how to meet an imminent death with grace, courage and wisdom.
What a contrast between the sense of darkness, denial and disaster embedded in those hospital patients and their families, and the vivid celebration of life and love that surrounded Edwards as she died among loved ones, in her own home. What a gift to see her carefully take her leave, imprinting memories on friends and children to inspire and guide them their whole lives.
While there was a fight to win, Mrs. Edwards fought hard. But unlike the dying patients in the Frontline piece, medical science served her needs, not the other way around. While the Frontline doctors asserted that long-shot, dangerously intense treatments are to be endured as what "drives medicine forward," Edwards' physicians candidly advised her further treatment would be "unproductive."
Thus, medical science released her to her own best judgment. Elizabeth Edwards possessed the intellect, stature and courage to negotiate that release. The choice of dying in peace and comfort should not be the exclusive domain of those with money, power and negotiation skills. Hospice, the great idea almost entirely absent from the Frontline piece, should be the treatment of choice for everyone in the situation Edwards faced.
CNN noted this well. They quoted Dr. David Casarett, of the University of Pennsylvania. "People in hospice don't want to die. They want to live, and they want to live well," he said. "They want to use whatever time they have to live the best way they can. I don't think it's giving up. It's making a careful choice. The easiest thing is to go after treatment after treatment, and say yes to whatever gets offered next," Casarett added. "The bravest thing is asking yourself what's important, who's important, what's best for you and your family and choosing hospice that way.
Elizabeth Edwards did all that in spades. She understood Dr. Casarett's words, their wisdom and their promise of hope: "Throughout my life, both personally and professionally, I have had the opportunity to see how people have been affected by illness and loss and the role the healthcare system may have played as they dealt with change in their lives. I also know that people can find a great deal of hope even in the most challenging of life's situations. Hospice and palliative care professionals support and care for people at a time when hope can be hard to find."'
When hope of conquering cancer becomes vanishingly small, another hope arises. This is the hope of dying well, dying gently and in comfort and peace with loved ones close. Elizabeth Edwards hoped for that and achieved a great success in making it happen. May her lesson help light the way and heal our broken manner of dying in America.


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Gorge Amphitheatre
George, Washington 98848
Venue Website
Venue DetailsExpand - Will Call, Parking, Directions, and more
Will Call Info
Tickets held at will call can be picked up on the day of the performance during the Box Office hours of operation. (Subject to change). The customer must present a valid form of identification, the actual credit card used, and the confirmation number to pick up their tickets.
Public Transit Info
No direct public transportation to the Gorge.
Parking Info
The Gorge Amphitheatre has two parking options; Regular or STAR Parking. Designated parking area for physically challenged patrons is available at the front gate. Please follow the signs or parking staff direction upon entering the main lot. The parking lot gate opens normally opens at 12:00pm. Times may vary depending on the event. Sorry, no overnight parking. (See "Gorge Camping") STAR PARKING: $30 per Vehicle Upgrade to STAR Parking for convenient parking. Benefit from the easy access and exit to and from this reserved parking lot. You will be guaranteed a spot within easy reach of the main gates. Sorry, no overnight parking. For overnight stays please see the camping section. Please note: By order of the Grant County Sheriffs Department, there is no parking or camping on county roads or private property leading to or adjacent to the venue. The county ordinances strictly prohibit the consumption of alcoholic beverages in the parking lot, and these laws will be strictly enforced.
Misc. Info
Camping: For more information on The Gorge and the Gorge Campground visit www.GorgeCamping.com where you will be able to purchase camping passes. Because the weather conditions can be extreme in Central Washington, it is recommended that you bring a hat, sunscreen, and sunglasses for daytime, and a sweater or jacket for after dark. A small flashlight may also be helpful. General admission may bring a small blanket, small umbrella, and a cushion, or a low lawn chair to all shows (subject to artist approval). For more Gorge information, email to: firstname.lastname@example.com or visit gorgecamping.com. Restaurants and Hotels: Hospitality info on hotels, resorts, restaurants, and gasoline is available from the following agencies: Quincy Chamber of Commerce............(509) 787-2140 Ellensburg Chamber of Commerce........(509) 925-3137 Moses Lake Visitors Bureau...........(509) 765-7888 Wenatchee Visitors Bureau............(509) 662-4774 Ephrata Chamber of Commerce...........(509) 754-4656 Yakima Visitors Center................(509)248-2021
Please use the interactive DIRECTIONS button above.
General Info
Open only during the day of show, normally 90 minutes before main gates open. (Subject to change for early show times). Doors open approximately 2 hours prior to show time (subject to change).
Payment Options
U.S. Cash, MasterCard, Visa, American Express and Discover.
General Rules
For the safety of all Gorge patrons, please follow these simple rules: * No alcoholic beverages can be brought into the venue. There are alcohol beverage stands and lounges where you may purchase throughout the venue. Please bring a valid WA State approved ID. Acceptable forms of ID: A Driver License, ID Card, or Instruction Permit issued by any U.S. State or Canadian Province. A Washington Temporary Driver License (paper license). A U.S. Military ID. An Official Passport. A Merchant Marine ID. A Washington State Tribal Enrollment Card. ALL RULES SUBJECT TO CHANGE WITHOUT NOTICE. Beer and wine can be purchased and can be taken to your seat in General Admission or Reserved areas. • No lounge and elevated chairs. Beach style are OK and rental chairs are available. • No laser pointers • Empty plastic drinking water containers will be allowed in. One factory sealed water bottles of 20 oz. size will be allowed in. Sorry, no factory sealed soda bottles please. • Food in clear plastic gallon sized bag (one per patron) will also be allowed in. No large, hard-shelled coolers or ice chests. • School-size or small backpacks are normally allowed in, but may be subject to change at the artists request. All bags are subject to visual search. • Emergency medical personnel and ambulance transport on site. Camera Policy: Personal cameras are allowed in the venue. Flash photography, video and removable lens cameras are not permitted without venue approval. Subject to change.
Child Rules
Children under the age of 2 are free in general admission seating. Every one including children will require a reserved ticket to access the reserved seating area. All ages are allowed inside the amphitheatre.
Upcoming Shows | Past Shows
Apr 30 Wednesday @ 11pm
May 23 Friday @ 12pm
Jun 6 Friday @ 5pm
Jun 6 Friday @ 7pm
Jun 7 Saturday @ 2pm
Jun 27 Friday @ 5pm
Jul 4 Friday @ 8pm
Aug 1 Friday @ 8pm
Aug 7 Thursday @ 3pm
Aug 8 Friday @ 7pm
Aug 9 Saturday @ 8pm
Aug 16 Saturday @ 7pm
Aug 23 Saturday @ 6pm
Aug 29 Friday @ 3pm
Aug 29 Friday @ 3pm


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View more Rings
View more Spring/Summer 2013 Jewellery
Spring/Summer 2013 Jewellery
Item: 201730
The Armour Ring is made up of four armadillo inspired overlapping sections that encapsulate the finger and move with it. This gold plated sterling silver ring has a Westwood Orb in relief on the first of the armoured sections.
Ring Length •3.8cm
Delivery costs and options to United Kingdom:
5 Working Days £ 5.50
Next Working Day £ 8.00
Saturday Delivery £ 10.50
Our Next Day Delivery Service is available on orders placed before 3pm and is subject to orders successfully passing our security checks and will be delivered by courier between 9.00 and 18.00 the following working day (Monday - Friday).
In order to ensure Saturday Delivery orders must be placed before 1pm on Friday.
An additional £ 3 will be charged when shipping footwear due to the weight of these goods.
If you are not completely satisfied with your purchase we welcome exchange or refund on most* products.
Simply return your items to us in their original, unused condition within 14 days from the date of delivery by trackable mail.
Items must be sent in their original packaging with the swing tags attached.
*PLEASE NOTE that we DO NOT accept returns on earrings, swimwear or underwear due to hygiene reasons. This does not effect your statutory rights.
Vivienne Westwood is unfortunately not able to cover the cost of returns, however we will happily ship your exchange free of charge where the correct product is available.
Gold Plated Silver
This product is out of stock
We will notify you when the item becomes available:
Need Assistance? Email us


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Portero respects the brands we serve. We guarantee the authenticity and condition of all merchandise. We ensure the highest level of service and security. That's our promise. And we don't take it lightly.
One of the best options on the web
for buying authentic merchandise.


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This HOWTO explains how to extract embedded bitmaps (sbits) out of CJK TrueType fonts, generating high quality bit-mapped fonts for X11. Included are several encoding maps for Chinese, Japanese, and Korean encodings. Most CJK TrueType fonts include embedded bitmaps for 10, 12, 14, 16, 18 and 20 point sizes.
Cyrprint converts postscript files generated by netscape (original pages must be in koi8 encoding). It can be used as a pass-through filter. It adds cyrillic fonts to the beginning of the file and substitutes font names in the original PS document. The substitution and addition of fonts can be controlled with styles.
FreeType 2 is a high-quality and portable font engine that is capable of supporting several font formats (be they bitmapped or scalable) through a simple and uniform interface. Its design is modular and allows independent "font driver" modules to be added, even at runtime, to support additional formats. It also provides a high-quality anti-aliasing renderer, an innovative auto-hinting engine, and support for the following font formats: TrueType Type1, CID-Type 1, Multiple Masters Type 1 OpenType/CFF, pure CFF, and CEF Windows FNT/FON.
Hamster Font Manager (HFM) helps you control the avaliability of fonts in all of the supported applications from a central place. It includes modules to support X11, Ghostscript, and TeX. A PostScript module handles PS Fonts while other fonts remain untouched by this program. It features a nice Tcl/TK GUI. For X11 configuration to work, this software has to run on the machine's own X Server.
The jmk-x11-fonts package contains character-cell fonts for use with the X Window System. These fonts attempt to be practical while also remaining both legible and aesthetically pleasing. A wide variety of font sizes are available in both medium and bold weights and in a number of ISO-8859 standard encodings.
The mminstance package creates instances of PostScript Type1 multiple master fonts. (An instance is a version of the font as it looks at one point in its design space.) Mminstance lets you use multiple master fonts with programs that don't handle them directly, such as afm2tfm, ps2pdf, ps2pk, and X Type1 font servers. Mminstance contains two programs. Mmafm creates AFM font metrics from multiple master AMFM and AFM files, and Mmpfb creates a single-master font outline file (PFA or PFB) from the multiple master font itself.
A program that backs up and restores data.
A MoinMoin appliance that is easy to use and lightweight.


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Let your imagination run wild. Go on a printable maze adventure with your kids. Some maze games double as coloring pages!
This bewitching maze has a bat or a wrong turn around every corner. It will keep the kids on their toes, but hopefully not up all night.
Find the guilty party with this secret joke decoder, another great printable April Fools' Day prank the kids will love. This funny printable activity comes complete with riddles and paper magnifying glasses.
This downloadable Halloween fun sheet includes a dizzying maze to get lost in, and a few ghostly-looking Halloween characters who need some coloring in by some crafty kids.
Kids will have fun coloring-in this Thanksgiving placemat activity.
Let Mickey and his pals entertain you while waiting for the big countdown on New Year's Eve.


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Prevention of Cystic Fibrosis Diabetes
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Acute systemic hyperglycemia causes oxidative stress and a pro-inflammatory response. The pro-inflammatory cytokines induced by hyperglycemia are toxic to islet insulin producing cells, and thus worsen glucose intolerance. Patients with cystic fibrosis (CF) have a high prevalence of CF related diabetes (CFRD) and up to 40% of CF adults develop CFRD. During the prediabetic phase in CF, there is progression from normal glucose homeostasis to high risk prediabetes characterized by episodes of acute hyperglycemia after meals and during respiratory exacerbations. The mild hyperglycemia seen in CF patients with high risk prediabetes following a meal would be expected to induce a degree of systemic inflammation and oxidative stress. These repetitive episodes, if left unchecked, could lead to progression of glucose impairment, worsening severity of oxidative stress and inflammation, and ultimately the development of CFRD, all via hyperglycemia-induced toxicity to beta cells. Furthermore, this process may be accelerated in CF because lung disease and resultant respiratory exacerbations are associated with oxidative stress and inflammation and this will further contribute to beta cell damage.
Sitagliptin is a recently approved agent for type 2 diabetes and markedly enhances insulin secretion in the presence of hyperglycemia and has been shown to be effective in preventing postprandial hyperglycemia. The hypothesis to be tested in this project is that sitagliptin will prevent the development of CFRD in CF subjects with high risk prediabetes by blocking postprandial hyperglycemia. The investigators propose a randomized, double-blind, placebo-controlled, multicenter, 27-month longitudinal study in 186 CF subjects with high risk prediabetes to test this hypothesis. Specifically, the investigators aim to show that chronic treatment with sitagliptin: prevents the conversion to diabetes; results in preservation of beta cell function; reduces systemic measures of oxidative stress and inflammation; and slows the rate of progression of lung disease.
Funding Source - FDA Office of Orphan Products Development
Cystic Fibrosis
Drug: Sitagliptin
Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator)
Primary Purpose: Prevention
|Official Title:
|A Randomized, Double-blind, Placebo-controlled Study to Determine Whether Chronic Treatment of Cystic Fibrosis Subjects With Impaired Glucose Tolerance Using Sitagliptin (Januvia) Prevents the Development of Diabetes
- Conversion to cystic fibrosis related diabetes [ Time Frame: every two weeks for 2 years ] [ Designated as safety issue: No ]
- Preservation of beta cell function [ Time Frame: every 6 months for 2 years ] [ Designated as safety issue: No ]
- Reduction in airway redox imbalance, oxidative stress, and inflammation [ Time Frame: every 6 months for 2 years ] [ Designated as safety issue: No ]Only in a subset of subjects
- Reduction in systemic redox imbalance, oxidative stress, and inflammation [ Time Frame: every 6 months for 2 years ] [ Designated as safety issue: No ]
- Slow the rate of progression of lung disease [ Time Frame: every 3 months for 2 years ] [ Designated as safety issue: No ]
|Estimated Enrollment:
|Study Start Date:
|May 2010
|Estimated Study Completion Date:
|July 2017
|Estimated Primary Completion Date:
|July 2017 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Sitagliptin
CF patients receiving Sitagliptin.
Intervention: Dose is 100 mg taken orally once a day in the morning with breakfast. Duration is two years or until converted to CF diabetes, whichever comes sooner.
Drug: Sitagliptin
100 mg of sitagliptin is taken orally each morning with breakfast. Duration is 24 months or conversion to CF diabetes, whichever comes first.
Other Name: Januvia
Placebo Comparator: Sugar pill
CF patients receiving placebo.
Intervention: Placebo is taken orally once a day in the morning with breakfast. Duration is two years or until converted to CF diabetes, whichever comes sooner.
Drug: Sitagliptin
100 mg of sitagliptin is taken orally each morning with breakfast. Duration is 24 months or conversion to CF diabetes, whichever comes first.
Other Name: Januvia
Show Detailed Description
|Ages Eligible for Study:
|13 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Aged 13 years of age or older at the time of enrollment
- Diagnosis of cystic fibrosis (CF) confirmed by pilocarpine iontophoresis sweat chloride measurements and/or genotyping
- Clinically stable with no lower respiratory tract exacerbation requiring intravenous antibiotics in the three weeks prior to enrollment
- On a stable clinical treatment regimen for at least three weeks prior to enrollment
- Male or female. If female, is not lactating and has a negative pregnancy test at screening. If female of child bearing potential, willing to practice effective birth control (i.e. a method known to decrease the risk of pregnancy to less than 1%)
- Able to understand and provide informed consent
- Willing and able to comply with the study schedule and testing
- High risk prediabetes as defined by high-risk impaired fasting glucose levels of 110-125 mg/dl and/or a 2-hour plasma glucose level of 140 to 199 mg/dl found on an Oral Glucose Tolerance Test performed at screening 8 weeks or less before enrollment
- Available by telephone
- Has literacy and language skills required to fill out study material
Exclusion Criteria:
- Diagnosed with CF related diabetes
- Chronic heart failure with NYHA class III/IV, ejection fraction less than 25%, or receiving digoxin
- Liver disease as defined by ALT or AST three times above the upper limit of normal.
- Serum creatinine greater than 1.3 mg/dl for males and greater than 1.1 mg/dl for females or receiving chronic dialysis
- Taking chronic oral or intravenous glucocorticosteroids during the past month
- On insulin therapy during the past month
- CF lung disease severe enough to require daytime chronic oxygen therapy via nasal cannula during the past month
- Unable to perform pulmonary function testing
- History of any illness or condition that, in the opinion of the sponsor might confound the results of the study or pose an additional risk in administering study drug to the subject
- Post lung or liver transplant
- Listed and awaiting organ transplant
- Current drug or alcohol dependency
- Participating in another clinical drug trial or past participant within 30 days of enrollment
- Pancreatic sufficient
- History of acute pancreatitis as documented by characteristic clinical manifestations and elevation of serum amylase and lipase within the last 2 years.
- Using overnight enteral tube feedings in the previous six weeks.
|Contact: Arlene A Stecenko, MD
|404 712 2657
|United States, Georgia
|Emory University and Children's Healthcare of Atlanta at Egleston
|Atlanta, Georgia, United States, 30322
|Contact: Arlene A Stecenko, MD 404-712-8283 email@example.com
|Principal Investigator: Arlene A Stecenko, MD
|Children's Healthcare of Atlanta at Scottish Rite
|Atlanta, Georgia, United States, 30342
|Contact: Kevin Kirchner, MD 404-252-7339 email@example.com
|Principal Investigator: Kevin Kirchner, MD
|United States, Ohio
|Nationwide Children's Hospital
|Columbus, Ohio, United States, 43205
|United States, Tennessee
|Vanderbilt University Medical Center
|Not yet recruiting
|Nashville, Tennessee, United States, 37232
|Contact: Howard B Baum, MD, PhD 615-343-8332 email@example.com
|Principal Investigator: Howard B Baum, MD
|Canada, Quebec
|Institut de Recherches Cliniques de Montreal
|Not yet recruiting
|Montreal, Quebec, Canada, H2W 1R7
|Principal Investigator: Remi Rabasa-Lhoret, MD
|Principal Investigator:
|Arlene A Stecenko, MD
|Emory University
No publications provided
|Responsible Party:
|Arlene Stecenko, Associate Professor, Emory University
|ClinicalTrials.gov Identifier:
|NCT00967798 History of Changes
|Other Study ID Numbers:
|Study First Received:
|August 27, 2009
|Last Updated:
|March 13, 2014
|Health Authority:
|United States: Food and Drug Administration
Keywords provided by Emory University:
cystic fibrosis
oxidative stress
redox balance
lung disease
Additional relevant MeSH terms:
Cystic Fibrosis
Glucose Intolerance
Prediabetic State
Pancreatic Diseases
Digestive System Diseases
Lung Diseases
Respiratory Tract Diseases
Genetic Diseases, Inborn
Infant, Newborn, Diseases
Pathologic Processes
Glucose Metabolism Disorders
Metabolic Diseases
Diabetes Mellitus
Endocrine System Diseases
Dipeptidyl-Peptidase IV Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Hypoglycemic Agents
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on April 23, 2014


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Mr. D | Season 1, Episode 3 | Jan 23, 2012 | 22:30
103 - Grade the Teacher
When Gerry sees how many positive reviews Dwyer has on gradetheteacher.com, he embarks on a campaign to match him somehow. Meanwhile, Simon takes Bobbi's advice to stand up to a student but ends up making all the other kids think he's crazy.