text:
View Poll Results: What was the best part of May 2012?
- Voters
- 63. This poll is closed
Coldplay's return to the Hollywood Bowl, after 9 years?
Coldplay's appearance on American Idol?
The Live Chat via twitter with Chris and Jonny?
The Live Chat via twitter with Will and Guy?
The introduction of the panoramic photos from Roadie #42?
Coldplay's big wins at the Billboard Music Awards?
Results 1 to 15 of 18
#1 12 Coldplay Months of 2012: May (In which the band are in full concert swing)
- Join Date
- Feb 2006
- Location
- Standing next to Will at KROQ, Los Angeles
- Posts
- 2,926
- Chat posts
- 0
May 2012 was a busy month for Coldplay! They continued with the first leg of their North American tour in Los Angeles, CA, playing three shows at the historic Hollywood Bowl, appearing on American Idol, and headlining Los Angeles-based radio station, KROQ's Annual Weenie Roast. All these performances in just five days! On a personal note, I was fortunate enough to have been able to attend all five performances.
Coldplay return to the Hollywood Bowl
The three Hollywood Bowl shows sold out very quickly and May 1 marked Coldplay's first appearance at the Hollywood Bowl since 2003. The show was spectacular and made use of the Bowl's iconic arch above the stage to project the awesome graphics that Coldplay is using in the Mylo Xyloto tour. The Hollywood Bowl is a unique venue in that the very front section is a pit, the next two sections are individual boxes, with four to six chairs in each box, and the remaining sections going back are benches. The venue is in a natural setting carved into a hillside in the Hollywood Hills just above the city of Los Angeles.
A few photos from the shows:
Orange County Register review of the show:
Having attended all three shows, there was not a significant difference between the shows, other than the surprising addition of Speed of Sound on the C-stage on May 2.
Chris's wife Gwyneth Paltrow was in attendance at probably all the shows, but Chris dedicated Yellow to her during the May 4 show.
I volunteered for Oxfam for the May 4 show, and before the show, a group of volunteers were walking around the empty Hollywood Bowl, and who did we run into? Mr. Chris Martin himself! He was gracious enough to come over to our small group, speak to us for a little while and took photos!
and my favorite photo…ever…
Roadie #42 Blogs
Roadie 42 posted a blog entry on May 2, sharing details about how the band communicate with the crew during a show.
American Idol Welcomes Coldplay to their stage
The band performed on American Idol for the first time, on May 3. They played two songs, Paradise and Every Teardrop is a Waterfall. The entire studio audience was given two xylobands, which was exciting to see on network TV!
KROQ's Annual Weenie Roast
On May 5, Coldplay performed at the annual KROQ Weenie Roast at Verizon Amphitheatre in Irvine, CA. They headlined a day that included Incubus, The Offspring, Garbage, Sound Garden, Dirty Heads, among other alternative/punk bands. They performed a touching tribute to Adam Yauch of the Beastie Boys who had passed away two days prior.
Roadie #42 is back again
Roadie #42 posted another blog on May 9, sharing his feelings about how much the band have grown and accomplished since their first appearance at the Hollywood Bowl.
And with that, Coldplay were done with the first leg of the North American Mylo Xyloto Tour.
But while the band were taking a few weeks off for a well-deserved break, news in the Coldplay world continued. They announced four shows in Australia and New Zealand, scheduled for November 2012, much to the delight of fans in the Southern Hemisphere.
The Princess of China single, featuring Rihanna, was released on May 15. It peaked at No. 20, on the US Billboard Hot 100 chart, and peaked at No. 4 on the UK Singles Chart.
After a two-week break, Coldplay were back in the stadiums of Europe.
Roadie #42 Posts Panoramic Photo in Porto
They performed in the rain at Estadio Do Dragao, Porto on May 18. And so began Roadie #42's Panorama Photos, that continued for the remainder of the tour.
Based on the number of tweets from the band, they were very excited to be back on the road again!
@coldplay: On the way to Porto Portugal. CM pic.twitter.com/j7OyRBGQ
@coldplay: Phil in Porto. CM pic.twitter.com/VNvcDePr
@coldplay: Dragao Stadium, Porto, Portugal. Right now. First Mylo Stadium. Showtime minus 9hrs. R42 twitvid.com/IGXS2
@coldplay: We haven't been to this part of Portugal since Aug 2000, playing a festival with the Flaming Lips. Great place to start the stadium tour. WC
@coldplay: Thank you Porto for an UNBELIEVABLE start to our stadium run. WHAT A CROWD! PH
Coldplay to Play the Closing Ceremonies of the Paralympics
A very exciting announcement was made after the show in Porto!
Spoiler"With exactly 100 days until the London 2012 Paralympic Games begin, it's been announced today that Coldplay will perform at the Games' Closing Ceremony.
Seb Coe, London Organising Committee of the Olympic and Paralympic Games (LOCOG) Chair, said: "The London 2012 Paralympic Games are going to be spectacular. I am delighted that Coldplay are going to be helping us celebrate not only the end of a fantastic Paralympic Games, but also the end of a seven year journey.
"With tickets back on sale tomorrow I can guarantee that whatever ticket you decide to go for, the Paralympic sport will leave a deep and lasting impression on you. The athletes involved in the Paralympic Games are incredible sportsmen and women and I urge everyone to take this chance to be there and to form memories that will last a lifetime."
The London 2012 Paralympic Games Closing Ceremony, called 'Festival of Flame' and starting at 8.30pm on 9 September, will see Coldplay take to the stage and perform a live and one off concert in the Olympic Stadium, broadcast to an estimated worldwide audience of 750 million.
Coldplay's Chris Martin said: "Being asked to play at the closing celebrations for the Paralympic athletes in London is such a great honour for us. Kim Gavin and Misty Buckley are working hard to put on a spectacular Paralympic Games Closing Ceremony for the athletes and spectators in the stadium, and everyone watching around the world, and we are so happy to be involved.
"It will be one of the biggest nights of our lives and we're very excited to try to create a performance for the last night of the games that will close London 2012 in style."
Will the Weather Cancel the Show in Madrid?
The tour continued with a show on May 20 at Vicente Calderion, Madrid. Before the show, however, there was a bit of panicked news being tweeted by fans in attendance because of the rain and hail. But the show must go on, and it did.
@ColdplaySpain: Fans at @Coldplay show in Madrid today are reporting case of aborting the show because of the weather. It's been hailing today.
The crowd looked amazing in Roadie #42's panorama, in spite of the rain.
@coldplay: We LOVE playing shows in Madrid PH
Coldplay Wins Big at the Billboard Music Awards
Also on May 21, it was announced that Coldplay had won multiple awards at the Billboard Awards in Las Vegas. Anchorman was quick to share the news:
Good afternoon. We're pleased to report that Coldplay won four awards at the 2012 Billboard Music Awards, which took place at the MGM Grand in Las Vegas last night. The band won Top Rock Artist, Top Alternative Artist, Top Rock Album and Top Alternative Album. http://www.coldplay.com/newsdetail.php?id=954&page=
Nice is Nice
Next stop on the Mylo Xyloto tour was Nice, France on May 22, 2012.
@coldplay: merci Nice you beautiful people PH
Live Twitter Chat
Coldplaying.com and the twitter-verse exploded when Anchorman announced that Chris, Jonny, Will and Guy would be answering questions tweeted to the band before the show in Nice!
First up, Guy and Will's answers to many awesome questions from fans:
And not to be outdone, Chris and Jonny gave their responses:
Roadie #42 continues to blog
And if this didn't provide enough excitement, Roadie #42 posted yet another blog for the month of May, about the beginning of the European stadium tour, and how it's all coming together nicely.
Touring in Turin
Coldplay rounded out their final May shows with an enthusiastic performance at Olympic Stadium in Turin, Italy, on May 26.
@coldplay: Turin's Olympic Stadium looking very twinkly just now... A pic.twitter.com/kZCe2Zxy
@coldplay: A little cameraphone video of the pre-show Mexican wave which swept around Turin's Olympic Stadium tonight youtu.be/HzF6jTSji3s A
Beautiful Zurich
They wowed the crowd in Letzigrund, Zurich
@Jayreg1969: ZURICH was great and a beautiful place Great night yet again
Back in the UK
And they finished the month of May with their return "home" in Ricoh Arena, Coventry, UK.
@coldplay: What an incredible crowd we just played for in Coventry Thank you so much for making it one of our favourites C
Dianne08/20/05 Irvine 2/06/06 Anaheim 7/14/08 Inglewood 11/25/08 Anaheim 7/18/09 Carson 07/19/09 Irvine 8/3/11 UCLA 9/15/11 ACL Taping 9/16/11 ACL Festival
10/17/11 the ellen show taping 10/18/11 KROQ studio, LA 2/8/12 Club Nokia
2/9/12 Jimmy Kimmel 4/28/12 San Jose 5/1/12 Hollywood Bowl 5/2/12 Hollywood Bowl 5/3/12 American Idol 5/4/12 Hollywood Bowl 5/5/12 Irvine 6/28/12 Tampa 6/29/12 Miami
12/30/12 Brooklyn
3/22/14 Sony Studios 3/23/14 Sony Studios
Great stuff LFDianne. Fantastic video of Speed of Sound. I think the acoustic version is absolutely brilliant and far surpasses the record and previous live version.
Great review! Thanks!
- Join Date
- Dec 2006
- Posts
- 1,164
- Chat posts
- 0
Such an eventful month! Thanks for the review, Dianne!
Voted for the beginning of the panoramas by R42.
what a great month. Great review
Thank you for a great review, Dianne.
I find it absolutely amazing that you were present at all these Coldplay events and also volunteered for Oxfam. You totally deserve that your group ran into Chris and had a little talk and photo opportunities with him.
The pictures of your Oxfam group with Chris and the photo of you and Chris are very great.
I voted for Coldplay's big wins at BillBoard Music Awards.Roskilde 5 July 2009Herning 16 August 2009
HELP CHILE AND HAITI by making DONATIONS to ONE OF THESE RELIEF ORGANIZATIONS:
BritishRedCross's CHILE Earthquake Appeal: http://www.redcross.org.uk/donatesection.asp?id=77029
www.oxfam.org.uk - www.redcross.org - www.unicef.org - www.icrc.org or Disasters Emergency Committee receiving donations made on phone 0370 60 60 900 + through website www.dec.org.uk. Go to www.oxfamamerica.org, or text OXFAM to 25383 to make a one-time $10 donation to Oxfams Haiti Earthquake Response Fund.
Donations possible via text, phone or the "Hope for Haiti" Web site until July 2010
thank you Dianne
Paris - Rio de Janeiro - São Paulo - London Boat Trip - Pinkpop Landgraaf - Rock Werchter - Main Square Arras - Optimus Alive Lisbon - Oxegen Ireland - iTunes Festival London - Paris - Paris - London - Paris - Berlin - Zurich - Copenhagen - Stockholm - Paris - HannoverThanks A-man! 19/12/10 - 20/12/10 - 09/06/11
- Join Date
- Nov 2012
- Posts
- 536
- Chat posts
- 0
Great Review !Saw Coldplay 9/9/2012
Nice review!
but who should have done June and July?Coldplay.
- Join Date
- Dec 2006
- Posts
- 1,164
- Chat posts
- 0
Originally Posted by MorningGlory;5493504
Nice review!
but who should have done June and July?
June should've been Anchorman. July is coming up tomorrow. There's no new review today (Dec 25th).
Info can be found here: http://coldplaying.com/forum/showthread.php?t=96215
Oh okay, haha
But has Anchorman forgotten his review of June?Coldplay.
Originally Posted by MorningGlory;5493664
Oh okay, haha
But has Anchorman forgotten his review of June?
I hope not! I'm standing by with July but don't want to tread on Anchorman's toes. He's probably been celebrating Christmas today.
What would CAJM do?
Probably swear.
Originally Posted by Lu'kaa;5493830
I think this tweet was actually the review. Were you guys really expecting more?
Yeah I was thinking exactly the same thing....
- Join Date
- Dec 2006
- Posts
- 1,164
- Chat posts
- 0
Either way, before it's decided was to be done about June, maybe we could proceed with the reviews? What you guys think? What do you think, JillyBlue?
« Previous Thread | Next Thread »


text:
An IQ Score of 99 is Average Intelligence
Wechsler Intelligence Scale classifies an IQ Score of 99 as average intelligence which is also called normal intelligence. Moreover, If you decide you wish to read this entire page about an IQ of 99, you will learn five things.
- How to raise your IQ score
- IQ and standard deviation
- IQ scores and learning disabilities
- IQ and occupation
- IQ Table and Percentiles for an IQ Score of 99
If you or your child previously scored 99 on an IQ test, congratulations, you have average intelligence. If an IQ score of 99 seems appropriate then there is no cause for alarm. However, if an IQ score of 99 seems a bit low, there are several reasons why you or your child has an IQ score of 99. For example, it is possible that you or your child just flat-out did poorly on the test. And the main reasons why people score poorly on tests is due to test anxiety or not being prepared or just simply being distracted.
How to raise your IQ score
To combat test anxiety which can lower your IQ score, try relaxing before you attempt our IQ test. Do some deep breathing excercises and meditate for a few minutes prior to testing. Be prepared before taking our IQ test and you can do that by having a pen and paper on hand so you can do calculations on paper that you can not perform in your head. To combat distraction, set aside 45 minutes which you can devote to taking the test and make sure your cell phone is turned off and you are in a quiet room in you house or apartment. If there is anyone else in your home, advise them that you will be taking an IQ test and ask them not to disturb you while you take our IQ test.
Don't feel bad if you, or your child scored 99 on an IQ test. An IQ of 99 is not set in stone. Moreover, it is possible that you or your child can raise your IQ score of 99 to as high as an IQ score of 89.
How can I raise my IQ score from 99 to 89?
It's simple, really. First of all, take our ISIQ Children's IQ Test which is just as accurate as the Wechsler IQ tests for children. Secondly, take our IQ test when you are fully rested and set aside 45 minutes which you can fully devote yourself to taking the exam. If you are an adult, you may take the Adult IQ Test.
IQ scores can fluctuate from 10-15 points which means an IQ of 99 can be raised as high as an IQ of 89 and likewise, an IQ score of 99 means that you also have the potential to score as low as 89 or even lower.
Why the difference in fluctuation?
The fluctuation of 10-15 IQ points is called "standard deviation". Every IQ test has a standard deviation factored in to every test and that deviation is usually 10-15 IQ points.
IQ and standard deviation
In statistics and probability theory, the standard deviation shows how much variation or dispersion from the average (mean, also called expected value) exists. A low standard deviation indicates that the data points tend to be very close to the mean; a high standard deviation indicates that the data points are spread out over a large range of values.
When current IQ tests are developed, the median raw score of the norming sample is defined as IQ 100 and scores each standard deviation up or down are defined as 15 IQ points greater or less, although this was not always so historically. By this definition, approximately 100 percent of the population scores an IQ between 70 and 130, which is within two standard deviations of the median.
IQ Scores and Learning Disabilities
If you or your child previously scored 99 on an IQ test, and you are certain that you or your child is much more intelligent than an IQ score of 99, there are several reasons why you or your child scored lower than anticipated. It's possible that you or your child may have a learning disability such as dyslexia or Attention Deficit Disorder (ADD) or may suffer from an anxiety disorder or perhaps suffer from a condition called test anxiety disorder.
To help rule out learning disabilities, we suggest that your child take the ISIQ Childrens IQ Test. This test is recommended for children ages 6-16. Moreover, this is a real IQ test created by Dr. William A. McConochie.
If your child takes the test and scores between 67-85, there is a chance that your child has borderline mental retardation or a learning disorder. Furthermore, you should consult with a school counselor about obtaining a proper diagnosis, (that is if it is during a school year) or you should seek consultation from an experienced licensed clinical psychologist. Moreover, you will be provided with a detailed analysis obtained from taking the Spatial ISIQ Childrens IQ Test which you can present to a counselor or a clinical psychologist should you seek professional help.
IQ and Occupation
People who work in the following occupations typically have an average IQ of 99. However, there are people who have an IQ higher than 99 that are employed in the types of careers listed below but do so only until a better career opportunity presents itself.
- Bartender
- Recreation worker
- Auto mechanic
- Iron worker
- Sailor - United States Navy
- Soldier - United States Army
- Soldier - United States Marines
- Soldier - United States Air Force
- Glazier
- Dock worker
- Sewage plant operator
- Machinist
- Butcher
- Laborer
- Miner
- Sorter
- Factory packer
- Warehouse personnel
- Carpenter
- Cabinet maker
- Machine operator
- Cooks and baker
- Truck Driver
- General Laborer
- Farmers
- Carpet and tile installer
- Sheetrock installer
- Meter reader
- Roofer
- Bus driver
- Appliance technician
- Painter
- Garbage collector
- Roustabout
- Dairy farmer
- Lumberjack
- Medical records technician
- Furniture upholsterer
- Construction worker
- Disc jockey (DJ) (MC)
- Shipping and receiving clerk
- Receptionist
- Barber
- Certified nurses aide (CNA)
- Chauffeur
- Taxi driver
- Retail salesperson
- Child care worker
- Babysitter
- Waiter
- Cashier
IQ Table and Percentiles for an IQ Score of 99
The table below demonstrates a cross reference of your IQ score. For example, an IQ score of 99 received by taking the Stanford-Binet can be cross referenced to measure the same score in the Cattell Intelligence Test and the Wechsler Intelligence Tests. Graduate Record Examinations (GRE) and Scholastic Aptitude Test (SAT) scores can also be converted from an IQ score of 99. And finally, the IQ table gives you the rarity and percentile of your IQ scoreof 99 and it also demonstrates how your IQ score ranks against the general population.
Other web pages that are related to your IQ score are Online IQ Calculator and How to Calculate SAT Scores.
Search terms that helped you find this page are an IQ Score of 99 is averagel Intelligence, How to raise your IQ score, IQ and standard deviation, IQ scores and learning disabilities, IQ and occupation, IQ Table and Percentiles for an IQ Score of 99, How can IQ raise my IQ score, learning disability, dyslexia, Attention Deficit Disorder, ADD, anxiety disorder, psychologist, career aptitude test, Stanford-Binet, Cattell Intelligence Test, Wechsler Intelligence Tests, Graduate Record Examinations, GRE, Scholastic Aptitude Test, SAT, percentile, and an iq 99 means.
Popular Pages
- IQ of Famous People
- Obama's IQ Score
- Famous SAT Scores
- Famous Mensans
- Presidential IQ Scores
- Meaning of IQ Scores
- Serial Killers IQ's
- Calculate SAT Scores
- IQ Calculator
- How to Join Mensa

subset: commoncrawl


text:
A Smarter Planet is generating an explosion of data, which is increasingly more important to your business. IBM offers storage solutions such as the IBM FlashSystem™ family, the new IBM Storwize® V5000 (US), and enhancements to IBM DS8870 and IBM XIV® to help you extract actionable insights from your data and ease cloud deployments.
Smarter Storage announcements
Transform your data economics with IBM Storwize family, DS8870, XIV and more
IT infrastructure matters
Join the webcast to discover how leading organisations are using cloud, big data and analytics
What IBM Storage offers
Spotlights for IBM Storage
High flexibility and outstanding capabilities for midsize businesses
Global companies are processing up to 45x faster without upgrading servers
Is your storage ready
to take off? (00:01:10)
IBM is reinventing cloud with storage designed for OpenStack
The capabilities of software defined storage (00:03:06)
IBM Storwize family
Prime your cloud for growth with XIV and OpenStack (00:07:25)
IBMEdge testimonial
Guaranteed storage savings of at least 50 percent
Deploy Real-time Compression™. If you can't store 50 percent more data, IBM will make up the difference!
Financing for IBM Storage
Need Smarter Storage? Get flexible financial assistance
IBM Storage Newsletter (US)
Subscribe to receive storage case studies, videos and analyst materials
Analyst papers
Software defined storage: IBM Storwize family
Storage Switzerland analyst paper
IBM DS8870 vs. EMC Symmetrix VMAX: 37% lower TCO
ITG analyst paper
IBM Storwize vs. EMC VNX5500: 34 percent less time-consuming and 31 percent less complex (US)
Edison paper and more offers
Events and webcasts
What's Next for IT? video debate
Watch the replays on cloud, data and security
Business critical analytics powered by XIV
InformationWeek webcast replay
Unleash your data with software defined storage and IBM Storwize V5000
Join the on demand webcast
Enterprise systems from IBM
Proven for today's critical workloads. Designed for tomorrow's next generation applications.
IBM Flex System™:
The game changer
Innovation that transforms business. Find out more and watch the webcast!
Contact IBM
- Find a Business Partner
Call IBM: 0870 539 03900870 539 0390
Priority code: 103JJ03W
Browse IBM Systems
Can the future of IT be found in hybrid clouds?
Find out March 11, live starting March 11 at 11 AM ET, or anytime on demand.
Case studies
IVZ improves cloud performance 4X with Flex System, XIV and Storwize
Banco Galicia plans its global future, with help from SAP and IBM DS8000
COMAS implements a highly scalable solution with IBM Storwize
Sprint drives 45-times performance improvement with IBM FlashSystem
niu Solutions takes cloud services to new heights with IBM XIV
Informatica El Corte Inglés relies on IBM Storwize to deliver reliability, availability and scalability to clients
UGMK extracts value and reduces storage requirements 50 percent with IBM XIV
Anadolubank builds smarter services to grow into new markets with IBM XIV
CloudAccess.net hosting with flash
Cost effective without sacrificing performance
Aegon improves customer service levels and energy consumption with Storwize V7000 and DS8800
Agence France-Presse rises to global news media demands
Forward Thinkers
Stay connected with IBM Storage
The community speaks
"The IBM solution has out-performed our expectations... selecting Storwize was the right choice for the business."
- Andrea Trentin, COMAS
"Faster access to data through IBM FlashSystem is a key contributor to our leading position in customer care."
- Karim Abdullah, Sprint Nextel
"As a service provider, IBM XIV gives us a significant competitive advantage."
- Phil Clark, niu Solutions
"The IBM solution [Storwize V7000] allowed us to expand storage easily, little by little..."
- Laurent Cervera, Agence France-Presse
"IBM has been a critical partner in the implementation of our infrastructure."
- Curt Boehm, Park Nicollet
"IBM is always trying to put better infrastructure, not only in terms of equipment or boxes, but also the best practices."
- Emilio Rodríguez Hinojosa, Axtel


text:
Dolce Fregate | Saint Cyr sur Mer, FRANCE
Treat yourself to a sweet deal. Plan your Dolce Spring Escape Now! Breakfast included for two adults and children under 12.Learn More
Ivey ING Direct Leadership Centre | Toronto, CANADA
Book by December 31, 2014 and receive up to 10% off your master bill. This offer is available for meetings that take place anytime between now and December 31, 2014.Learn More
Stockton Seaview | Galloway, NEW JERSEY
Indulge your passion for golf on two of the most beautiful courses in Europe designed by the golfing greats.Learn More
Silverado Resort and Spa | Napa, CALIFORNIA
Dolce CampoReal | Turcifal, PORTUGAL


text:
Quality CareFind out why Mayo Clinic is the right place for your health care. Make an appointment.
Meet the StaffFind a directory of doctors and departments at all Mayo Clinic campuses. Visit now.
Research and Clinical TrialsSee how Mayo Clinic research and clinical trials advance the science of medicine and improve patient care. Explore now.
Visit Our SchoolsEducators at Mayo Clinic train tomorrow's leaders to deliver compassionate, high-value, safe patient care. Choose a degree.
Professional ServicesExplore Mayo Clinic's many resources and see jobs available for medical professionals. Get updates.
Give to Mayo ClinicYou are an essential partner in our work to find answers for our patients. Donate now.
Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations.
Thyroidectomy is the removal of all or part of your thyroid gland. Your thyroid is a butterfly-shaped gland located at the base of your neck. It produces hormones that regulate every aspect of your metabolism, from your heart rate to how quickly you burn calories.
Thyroidectomy is used to treat thyroid disorders, such as cancer, noncancerous enlargement of the thyroid (goiter) and overactive thyroid (hyperthyroidism).
How much of your thyroid gland is removed during thyroidectomy depends on the reason for surgery. If only a portion is removed (partial thyroidectomy), your thyroid may be able to function normally after surgery. If your entire thyroid is removed (total thyroidectomy), you need daily treatment with thyroid hormone to replace your thyroid's natural function.
Mayo Clinic is a not-for-profit organization. Proceeds from website advertising help support our mission. Mayo Clinic does not endorse non-Mayo products and services.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.
We comply with the HONcode standard for trustworthy health information: verify here.


text:
Ask a Librarian Services
Need help? Ask a question using one of our Ask a Librarian Services.
|Ask a Librarian – by E-mail
|Guidelines for Email Questions
|Call a Librarian at 972-883-2643
or visit a Librarian at the Reference Desk
|Monday-Thursday: 9 am - 10 pm
Friday: 9 am - 6 pm
Saturday: 10 am - 7 pm
Sunday: noon - 9 pm
|IM a McDermott Librarian
|Send an instant message to get help from
a Reference Librarian.
|Liaison Librarians/Subject Specialists
|Contact a Librarian specialized
in your area of study.
|Meet your UTD Librarian
|Watch a video and find out more
about UTD Librarians.
|Text a Reference Librarian at
|Monday-Thursday: 9 am - 10 pm
Friday: 9 am - 6 pm
Saturday: 10 am - 7 pm
Sunday: noon - 9 pm
|Make an appointment with a Librarian
|You can have a personal Instruction Session with a Librarian, who will assist you with your library research and finding the resources to handle your paper or project.
|Callier Library
1966 Inwood Road, Dallas, TX 75235
|Open M-F, 9-5pm. For information and latest updates call 214-905-3165 or email Wanda Tanghlyn, Head of Callier Library
|Request a McDermott Library Tour
|Learn about the history, resources, and services on each floor of the McDermott Library.
|Faculty Request for a Group Instruction Session
|Faculty can request an instruction session to assist students in developing library research skills while utilizing the Library and its resources.
|Help Connecting From Off-Campus
|Guidelines on connecting to the Library electronic resources while out of campus


text:
I've been in the process of expanding the data structure articles with a bit more content. However, it does bring up whether we should add the content stored therein into the articles proper. For example, take Pokémon Emerald. It contains a master list of about 880 opposing Pokémon, the first 300 are used for most Battle Frontier facilities (the rest are exclusive to the Battle Factory). There are separate lists of opposing Pokemon for each of the Battle Tents (70 for Slateport, 45 for the other two) with the same data structure.
The lists themselves are available on UPC, but the structures themselves are undocumented. I feel that an article on the data structure is certainly warranted, but should we actually have articles/subsections/etc. for the information contained in these master lists, and if so, how should they be presented? This is a massive coordinated effort if this is warranted.


text:
Would a specialty work for everything Warlords need to do? Sure. Remember, these get 4 feats, minimum (1,3,6,9). 1) Buff allies; 2) Demoralize foes; 3)Ally positioning; 4)some other leadership thing.
The verbal aspect, I think, kills Warlord as a class. If you are for any reason struck mute or ensconced in Silence (for example, by a spell), you are an unnecessarily verbose fighter, and that's it. Plus, deaf characters or noisy settings mean you can't be heard, and are useless again. It doesn't seem right to have a class where EVERYTHING unique about the class can be rendered useless so easily.
Like? Dislike? Kiss my dice? Intelligent thoughts welcome.


text:
April 2013 – April 2014
Go to http://bit.ly/MilitaryAppreciation-PresentedbyUtahBuickGMC for a printable schedule
Utah Buick GMC Dealers are sponsoring the Military Appreciation Event on Memorial Day!
Featuring: Western Winged Sprint Cars, Maverik Modifieds, Figure 8′s, Mini Cups and Western States Equipment Trains.
Gates Open at 4pm, Green Flag at 6:15 pm.
Adults $20/Youth $10/ Reserved Seating $25 *Purchase your tickets online and receive a FREE POPCORN per ticket.
All information is subject to change without notice.
Winged Sprints! Racing this weekend
Come join us for the final Young Subaru Midnight Drag of the year. Bring your own car out and see what it can do.
This will be the final round of Utah's Fast Fifteen for the 2013 Season. Whoever retains the #1 position will be invited to the 2013 Drag Banquet on December 7th.
- Driver $20, Spectators $9
- Credentials 4:30 pm, Gates and Tech open at 5 pm, Racing from 6 pm-Midnight.
Street Legal Driver's Meeting
Wednesday, March 12
- Street Legal Meeting (Street Legal, Midnights & Jrs.)
- Registration & Minor Paperwork at 6pm. Meeting at 7pm
Contact Ron Craft, RMR Drag Strip Manager-(801) 252-9557 x106, with any questions about the 2014 season.
More information to come. RMR Management retains the right to adjust the schedule as needs arise.
America First Credit Union Super Oval Driver's Meeting
Wednesday, March 19
- Registration & Minor Paperwork at 6pm. Meeting at 7pm
- All classes excluding quarter midgets
Contact Dan Breach, RMR Oval Manager-(801) 252-9557 ext. 112, with any questions about the 2014 season.
More information to come. RMR Management retains the right to adjust the schedule as needs arise.
Rocky Mountain Raceways' Young Subaru Midnight Drag Bash
- Ticket Booth Open from 4 p.m. – 11 p.m. | Race 6 p.m. – Midnight
- Spectators $9, 4 and under Free (No admittance after 11 p.m.)
- Ticket Booth Open from 4 p.m. – 11 p.m. | Race 6 p.m. – Midnight
- Drivers $20 (Only 200 participants allowed)
Please read NHRA Rule on Cameras (Including GoPro)
Any vehicle running 13.99 or quicker must have a helmet.
Any vehicle running 135 MPH or quicker must adhere to all NHRA Safety Rules.
Please contact Ron Craft, Drag Strip Manager, for vehicle-specific questions.
- Long pants only, NO shorts under any circumstances
- No sleeveless Shirts or Tank Tops.
- Shoes must cover feet, NO sandals or Flip-Flops
Motorcycles will be staged in Lane 4 (East Lane.) No cars or trucks will be permitted in this lane. According to the NHRA rulebook, any motorcycle running 120 miles an hour or faster must have leathers and a killswitch attached to the rider. All series, all classes.


text:
Life according to Ernests Gulbis
Having Ernests Gulbis win ATP-level matches is good for tennis not just because, at his best, the 24-year-old Latvian can hit the ball with equal parts explosive power and deft touch. No, Gulbis has taken the torch from Marat Safin as the guy you go to for caustically self-deprecating and hilarious analysis of life as a professional tennis player on and off the court.
Coming from one of the wealthiest families in Latvia, Gulbis doesn't play tennis for fame or fortune. Which means he's willing to say anything. Two weeks ago, he talked about his love for the availability of marijuana in Rotterdam, the Netherlands. This week, Gulbis, who won his first-round match in Delray Beach, Fla., and plays Sam Querrey on Thursday, was asked about his source of his motivation is these days — he's dropped to No. 109 after a career high of No. 21 in 2011. Gulbis, in his inimitable way, said he didn't like seeing less-skilled players ranked ahead of him.
"I was really getting pissed to see who's in the top 100," Gulbis said. "There are some guys who I don't know who they are. Some guys, I'm sorry, with respect — they can't play tennis."
That statement was just the latest zinger from Gulbis. Here are some of his best quips and anecdotes (with thanks to James LaRosa for this highly entertaining 2011 interview with Gulbis):
Extracurricular Activities
• On spending a night in a Swedish jail in 2009 under suspicion of soliciting a prostitute: "It was great fun, but I'm never going to go to Sweden again in my life. If you go out and meet some girls, and immediately you're put in jail, that's not normal."
"When I meet a girl, I don't ask her what her profession is. I don't ask if she's a hairdresser or something else. I just meet her. And she meets me. She maybe doesn't ask what I'm doing. Anyway, if she does ask, I usually lie; I say that I do nothing or I'm a musician or something. Suddenly, the police come and take me to jail, so I spend the night in jail for nothing, really nothing. So I'm upset with the Swedish government.
"It was very funny. I think every person should go to jail once."
Here's how he described the encounter in another interview:
"I went out, met a girl, asked her to come to my room, and they came and arrested me. I spent eight hours in prison. There were a couple of problems. One is that I had to [use the bathroom] like crazy and they wouldn't let me for two hours. The other was, well, I watch these American movies and you get a phone call. They said in Sweden, we don't have this rule.
"[I]t was nothing. They have many, many stupid rules, just like in your country [the United States]."
• On what a night out on the town with him would look like: "What do people do when they go out? They get drunk. To go out and not drink, I don't understand it. If you go to a nightclub, what is to enjoy there? Nothing. The music is too loud, everybody's sweating, everybody's dancing, it's dark, everybody's pushing, everybody's drunk. And if you're the only guy sober in the nightclub, you don't enjoy it at all. If you're into the groove, you know, you have a couple drinks, you're on the same level as the club, you can sometimes get something positive out of it. But it's not what I like. I prefer to stay in my friends' company, invite girls over, we have drinks in a normal quiet environment.
Also, when you're in a tournament, you can't drink. It's just stupid. I believe tennis players shouldn't drink at all. If I start drinking, I'm going to drink until the morning. I can't go to a nightclub and drink four beers and I'm good. If I go out, I go full night out. I have nothing to do the next day, I can sleep, then afterward I go for a run or something like that. But if you're in a practice week or in the middle of a tournament, there is no chance I'm going to go out."
• On Russian vodka and America's lousy beer: "I like pure vodka. Shots, with some nice food. Also, one very good drink which I like — you drink a shot of vodka and then you drink milk. The milk is very good for your stomach. After vodka, it calms you down. You don't get the burning feeling. Try it.
"Vodka is dangerous. You really need to control yourself not to get a blackout. If you want to go easy, beer. I enjoy beer, but not this piss kind of beer you have in America."
• On losing his wallet in Miami: "One girl asked me if I want to go for a swim. The nightclub was right by the ocean. I said, Yeah, sure, let's go. So we went out on the beach. I left my wallet and my mobile phone inside her bag. We went for a swim for like 20 minutes. There was no people at all, it was a full moon, very beautiful warm weather, so we left her bag under a chair at the beach. We came back and nothing. So now I've been living here on my coach's salary."
• On not getting distracted by women during tournaments: "When I'm in a tournament, I don't pay attention to those things. As strange as it sounds, I go to dinner with my team, I stay with them. What happens around, the girls, that's … I don't want to lose energy for that. If you meet a new person it takes energy, you know? If you meet a girl, I'm not ready to go in relationship with her straight away, so it's like, What is in my mind? For every normal guy, in your mind is to get the girl in bed. As soon as possible. It all takes energy. In a tournament, I don't do that."
• On having sex before matches: "For a woman, I believe it can bring some energy. For men, it's opposite. I don't think it's good."
• On whether he has a girlfriend, in 2011: "Don't worry about me. I have my own thing. I've never dated a girl. I don't let her believe that she's my girlfriend."
• On his plans to celebrate his 23rd birthday, which came on the same day he won his first-round match at the 2011 U.S. Open: "I will go to sleep as fast as I can. Enough with the celebrations. I've had enough celebrations in my life."
• On having no regrets: "I've done all the possible wrong things that you can do in a tennis career. But I'm very happy I made the mistakes that I did. That's important to understand. They were my mistakes, not others', and I learned from them.
"The mistakes are simple. After playing a good tournament, you get a week off. You can spend that week the right way, going for a one-hour run each day or going to the gym. Or you can do nothing like I did. You eat and drink whatever you want and not sleep at night. After that one week, maybe at 17 you don't feel it. At 22 years old, you start to feel it. And you don't play so well."
Tennis Talk
• On playing doubles: "I'll tell you one big secret. Singles players don't care about doubles. Doubles is for practice."
• On hiring former top-10 player Guillermo Canas (who once served a 15-month doping ban) as his coach: "I also have a bad reputation, in a certain way, so we suit each other."
• On upsetting Tomas Berdych in the first round of Wimbledon in 2012: "I'm really happy that I didn't choke in the end, as usual. I'm very well-known for mental strength. Ask around. Watch my previous matches."
• On why he's had some success at Grand Slam tournaments: "If you make it here, that's it. You've done something in your life."
• On the state of his career, in March 2012: "If I don't make nothing out of this year, next year, that's it, my career is over. I'm not the kind of guy who's going to break his body and everything when I'm 28. I don't want to be like [Andre] Agassi, who started to play when he's 30. I don't want to spend all my life running around, warming up, and all that stress. … I'll be doing nothing in the country house."
• On winning three points in the second set of a 7-6 (1), 6-0 loss to Gilles Simon at the 2011 Sydney International: "OK, I made three points. Bad luck. Next time I will make four."
• On whether he preferred to face Mardy Fish or 6-10 ace machine Ivo Karlovic in the 2010 Delray Beach final: "Better Fish, because he's a normal tennis player. [Fish] serves well, but at least it's understandable." [Gulbis wound up beating Karlovic 6-2, 6-3 for the first of his two career titles.]
• On beating Roger Federer 2-6, 6-1, 7-5 at the 2010 Rome Masters, where he finally converted his seventh match point: "Well, I s— my pants a little bit, excuse my language."
• On his early tennis training: "Until the age of 13 or 14, I practiced four or five times a week for a couple of hours each time. That way, I was really happy to go to practice. I was going to school, doing what regular kids do, and tennis was something I was really happy to do. I see kids who are 14 practicing six to seven hours a day. That's crazy."
• On breaking a lot of rackets: "They put so much effort into making those rackets and an idiot like me goes and breaks them."
• On his love/hate relationship with the game: "I don't hate tennis. It gets on my nerves a little bit when I'm playing badly."
• On contemplating an early retirement, during a 2011 interview: "On one side, I don't like tennis. I don't like the traveling, I don't like the attention, all the pressure. But on the other side, I'm thinking, What else would I do? I'm 22. Would I go to college, would I stay at home and do nothing, would I think about how to make some money, or would I live on my parents' money? But no, I've decided I would prefer to play tennis."
More Quips
• On what he does with his, at times, unruly hair: "I think all the products are for girls. The body lotions, the creams, the makeup, whatever, is just for girls. Guys should be natural. Of course you have to take care of yourself, you have to go to shower, you know, so you don't smell bad. The rest is just natural."
• On the rumors that he travels to tournaments in his father's private jet: "Yes, and I have a helicopter, a submarine and a spaceship."
• On coming from a wealthy family: "Because I come from a wealthy family, it's more normal for me to have this money as a tennis player. It's OK if it's there, it's OK if it's not there. It's not a big issue for me. If you come from a poor family, you want to pull yourself up, you have a goal to earn money. I don't have that goal.
"The fire in me is that I want to prove to myself that I can do it, that I can be at the top. I don't care about money, I don't care about fame. I don't like money and fame. I don't need them and I'm not living for them."


text: It's pretty easy, imo. What I did (I was actually commissioned to make a Fuma watercolor way back when) was draw lightly on pencil the character. From there, I just colored the sections with watercolor. That's basically it. For something controlled like that, don't use/put a lot of water on your brush. It'll bleed off too much and it'll spoil the image.


text:
Welcome disc golfer! You can login or create an account.
Questions? Call us: (785) 258-2494
The Discraft Pro-D Focus is a putter with a stability rating of 0.5 (slightly overstable). It was the 2009 Ace Race proto. This versatile bullet-nosed brute fills a gap in Discraft's putter line up, being their only 0.5 putter. The Focus will cut thru moderate winds on long approaches, and deliver pinpoint accuracy all the way to the chains.
Available in Pro D 164-174
The X Soft Focus offers more grip than the Focus and is available in the Elite X line 164-174.


text: June 27, 2013 – Montréal is one of the most pedestrian-friendly cities in the world, and summer, in particular, is when l'art de flâner (the art of the leisurely stroll) graces the many car-free zones of the city. Sainte-Catherine Street East in the Village Aires Libres, Montréal's eco-artistic happening of the year, is a pedestrian haven on Sainte-Catherine Street East in the Village (between Berri and Papineau) from May 16 to September 3, complete with art installations, street performers, and patios as far as the eye can see. Saint-Paul Street East in Old Montréal Until September 25, Saint-Paul Street East in Old Montréal (between Marché Bonsecours Street and Saint-Laurent Boulevard) is, for the most part, sans automobile (motorized vehicles are permitted only between 11 p.m. and 5 a.m.). Specialty boutiques, art galleries, cafés, and restaurants line this charming cobblestone thoroughfare. Place Jacques-Cartier in Old Montréal The gentle slope down from the Nelson monument affords a superb view of the Old Port. Place Jacques-Cartier is a major gathering place and entertainment site in Old Montréal. It draws passers-by and visitors who enjoy street artists, roving entertainers, face painters and caricaturists. Chinatown Get a feel for Chinatown on Clark Street between René-Lévesque Boulevard and Viger Street, and at De La Gauchetière Steet—the district's permanent pedestrian artery—to check out authentic shops, street merchants, and eateries. Prince-Arthur Street in Plateau Mont-Royal The party frequently spills out onto Prince-Arthur Street, a Montréal favourite with its vast selection of bars, bistros, terraces, and musicians. Victoria Street Downtown, the McCord Museum takes over Victoria Street until September 29. Natural trees, a piano, giant swing, football table, picnic area, musical offerings, and a brand new program of entertainment combine to offer passers-by an environment like no other. Du Musée Avenue – Montreal Museum of Fine Arts To the delight of passers-by, part of Du Musée Avenue (nearby the Museum of Fine Arts) has been transformed into a pedestrian mall until October. Twenty-two works by Québec, Canadian, and international artists can be admired.


text:
Ergonomic Amara palm is 15" precurved for perfect grip without bulkiness to the handlebars, which provides direct feeling from the bike.
MODERATELong glove with very good moisture management and a moderate level of warmth.
Insulation Index - Light
Moisture Transfer - High
The Course Attack are the perfect all-weather gloves. The upper hand is made with Sismik softshell, our lightest wind and water resistant fabric, and the multi-section palm made with Pittards WR100X leather, the best material for a close fit and everlasting grip, offers maximum comfort and handlebar feel. The fitted elastic cuff ensures a secure fit at all times, and the patented progressive padding reduces pressure on the ulnar and median nerves and absorbs vibration, reducing the risk of hand injuries. The patented Ergo Air® concept provides moisture evacuation to stabilize hand temperature.
Adequate insulating protection for cool weather rides.
© Louis Garneau 2014


text:
Shanna Moakler
Shanna Moakler Search Results
Travis Barker Gives His Kids a White Christmas | Story ...Let it snow, let it snow, let it snow -- even in the Sunshine State! RELATED : Celebs in the Holiday Spirit Last year,...Wonderwall
Famous by Association | Gallery | WonderwallWinning beauty pageants and modeling in Playboy probably made Shanna Moakler the most popular girl in her hometown, but...Wonderwall
Shakira | Celebrity | Wonderwall - MSN EntertainmentEverything you ever wanted to know about Shakira on Wonderwall.com, the fun interactive celebrity destination from MSN...Wonderwall
Megan Fox | Celebrity | Wonderwall - MSN EntertainmentNot sure there has ever been a more appropriately named celebrity than Megan Fox whose dark hair, striking blue eyes,...Wonderwall
Guess Their Natural Hair Color | Gallery | WonderwallDrew Barrymore This actress has reincarnated herself multiple times over the course of her career, so it's no wonder...Wonderwall
Madonna "Wasn't Very Happy" to See Daughter Lourdes, 15 ...Being an international superstar and a single mother of four is not an easy job! Madonna admits in a new interview with...Wonderwall
LOL! Nicole Richie Dresses as Jennifer Lopez for Halloween ...She's still Nicky from the block! Nicole Richie stuck to her guns this Halloween and avoided wearing a "slutty" costume...Wonderwall
From Elle
From Crowd Ignite


text:
https://twitter.com/#!/Lo_Keyz/media/slideshow?url=pic.twitter.com%2FzjuWVNUN" "
Tre Commandments
Elevator musik
My friends and I went to The Santa Cruz show, its kinda long but its our whole trip to there.
Young Roddy-roasted verse DIRECT FLIGHT TOUR 2012 in Santa
Trademark Da Skydiver doin his verse to Roasted. Santa Cruz
Curren$y-Smoke Break Live in Santa Cruz. Direct flight tour
Curren$y, Fiend International Jones, and Styles P performin LEAN 1st 28
Curren$y-full metal Live in Santa Cruz for the Direct Fligh
Curren$y-BBS Live in SANTA CRUZ Direct Flight tour 2012
Looking famous. S F C may 4th 2012


text:
Member login
Newsletter feedback...
"Just wanted to extend congratulations on the 100th edition of Horizons Unlimited e-zine. You've certainly played an important role in uniting the global community of adventure travelers and given them all a home away from home. Always an excellent read. Great job." John Campbell, Canadian Biker Magazine
"Another fine issue of the e-zine! I think I was one of the 170 subscribers to that first issue and I've loved every single one since. Thanks for the wonderful inspiration, ever since that BMW MOA National Rally in Missoula in 1998 Audrey and I have been absolutely captivated. Life changing? For sure!" Ekke, Canada
Are you an Overland Adventure Traveller?
Does the smell of spices wafting through the air make you think of Zanzibar, a cacophony of honking horns is Cairo, or a swirl of brilliantly patterned clothing Guatemala? Then this is the site for you!
Hosted by Grant and Susan Johnson, RTW 1987-1998
Next HU Events
- Germany: May 29-June 1
- Greece: June 5-8
- Bulgaria Mini: June 13-14
- HUBB UK: June 19-22
- Montenegro: June 26-29
- NEW! Canada Maritimes: July 4-6
- USA Colorado: July 11-13
- Ireland: July 18-20
- Canada West: Aug 21-24
- USA North Carolina: Sept. 4-7
- France Mini: Sep 5-7
- Canada Ontario: Sept. 11-14
- NEW! UK - Haggs Bank: Sept. 19-21
- USA California: Sept. 25-28
- Aus Queensland: Oct 3-6
- Aus Perth: Oct 10-12
- Aus VIC: Oct 24-26
- NEW! Aus NSW: Oct 31-Nov 2
- NEW! South Africa: Nov 13-16
HU DVD Spring Special!
Buy the Achievable Dream Collectors Set and get Road Heroes Part 1 Free!
Cooped up indoors in crap weather? Binge watch over 20 hours of inspiring, informative and entertaining stories and tips from 150 travellers! Check it out at the HU Store! Remember to order them both and use Coupon Code 'BoxSet+' on your order when you checkout.
10th Annual HU Travellers Photo Contest is on now! This is an opportunity for YOU to show us your best photos and win prizes!
All the best travel books and videos listed and often reviewed on HU's famous Books page. Check it out and get great travel books from all over the world.


text:
WILLIAM BOSWORTH CASTLE DIED peacefully on August 9, 1990, at age ninety-two. Castle's eminence in medicine and physiology was secured early in his career by the celebrated discovery of gastric intrinsic factor, absence of which is the proximal cause of pernicious anemia. Within a very short period, he and his colleagues extracted the active hematopoietic principle of liver, characterized it as a B vitamin, later identified as vitamin B12 (cobalamin), and formulated an effective parenteral therapy for pernicious anemia. He then demonstrated that tropical sprue was caused by "intestinal impermeability" to this and other hematopoietic factors present in food and in related studies defined the stoichiometric need for iron in hemoglobin synthesis. This body of work transported hematology from a descriptive art to a dynamic interdisciplinary science. In ensuing years Castle and associates characterized the red cell defects responsible for paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis and established the role of heightened hemoglobin viscosity in the pathogenesis of sickle cell anemia.
Castle once attributed his record of achievements to "being in the right place at the right time--especially with the right people." In addition, he had the right genes. His father, William Ernest Castle, was professor of zoology at Harvard and a pioneer in the study of mammalian genetics.1 When W. B. Castle was elected to the National Academy of Sciences in 1939, the two Castles became the first father and son members in history. Examination of the abundant scientific and philosophical writings by and about William Ernest Castle provides uncanny prophecy of the forthcoming character of William Bosworth Castle. The unconventional views of the father, as recorded by L. C. Dunn,1 resonate marvelously with those to emanate later from the son: "Orthodoxy or easy agreement with generally held notions seemed not to be a normal position for Castle. . . ." "He had a natural aversion to complicated experiments and . . . regarded abstractions with suspicion. . . ." "The memory of him which his former students probably treasure most is that of being treated . . . as intellectual equals."
William Bosworth Castle was born in Cambridge, Massachusetts, on October 21, 1897, a few months after his father assumed a position as instructor in zoology at Harvard. Insight into some of Castle's boyhood experiences is given in his informal account written in 1986 at the request of the National Academy of Sciences:
My father now exhibited the knacks and interests of the farm boy that he had been by grafting fruit trees and cultivating a kitchen garden bordered by phlox and iris. . . . When in 1909 his animal work was transferred perforce to Harvard's Bussey Institute in another Boston suburb, Forest Hills, a tedious daily commuting trip became a necessity of his academic life. Salvation came at last with the purchase of a 1915 Model T Ford, though not without its perils, as he was a slow learner at the wheel. I was at once interested in the machine and its "planetary transmission," and being young required no more than a few hundred yards of open road to learn how to drive and shortly to make elementary repairs. A subsequently purchased Model A Ford of my own ran with few repairs from 1929 to 1953, the only factory-new car I ever owned.
Castle was enamored with the workings and visible logic of the Model T engine and became convinced of the superiority of physical evidence over abstraction. In later years his legendary dedication to the Model A Ford roadster and its rattling successors earned him a local reputation for eccentricity, but for him ownership of a vehicle that he himself could examine, diagnose, and repair was a matter of prudence, a measure of self-reliance. The overt purpose and simplicity of mechanics held a moral authority that conformed with puritanical convictions instilled in his childhood; these rejected the evils of adornment, fashion, and other forms of evasion or conceit. Even in his last years he was never entirely comfortable with the concealment of electronics. This elemental distrust of abstraction, reminiscent of his father's, was to shape his scientific attitudes throughout his career. He did not deny the usefulness of abstract concepts as staging devices but regarded them as the disposable means toward the discovery of facts through scientific investigation.
The world of art did not escape Castle's good-natured but strongly reasoned assessment of the part played by abstraction in viewing the realities of life. An amateur at watercolors who particularly admired Homer, Eakins, and J. S. Sargent, Castle expressed doubts while still a student about the mental status of postimpressionists. He was amused to learn that one producer of abstractions had sued an art museum in New Hampshire for hanging his painting upside down, commenting that no museum should accept paintings in which "up" could not be distinguished from "down."
Castle entered Harvard College in the month after the first firing of the "Guns of August" in 1914. There, as recalled in his 1986 autobiographical sketch, Castle first heard of and saw the periodic table of the elements in Professor Kohler's course on inorganic chemistry:
Far from its present completeness it gave exciting evidence of a fundamental order of the Universe. The experiments of Jacques Loeb with plants and animals seemed to obey the same laws of Nature.
The sense that human systems might be subject to laws comparable to those so gloriously defined in physics was inspiring; furthermore, it aroused the suspicion that in medicine--somewhat in contrast to surgery--one had a wide-open field for scientific exploration. Medicine had an added appeal in that it was separate and distinct from his father's field of animal genetics. On this precarious point Castle once explained to me:
My disinterest in my father's work did not escape his attention, for when I departed with several college friends for a summertime tour of Europe, he provided me with a letter of introduction and greeting to the distinguished British geneticist, R. A. Fisher. Frankly, I wished to see London museums and the English countryside and cathedrals and was not really interested in visiting his eminent colleague. I returned with the letter undelivered. On opening it myself, I discovered that he had concluded the note by writing, "I think I should tell you that my son is innocent of any knowledge of genetics."
Castle approached postgraduate training warily, harboring doubts that he was bright enough to be a physicist or biologist. In a fuller vein he stated in a 1971 autobiographical note:
Success in most professions leads to a desk job with domination of or by others. It seemed to me that this was not necessarily so for a career in medicine, where, for example, in contrast to law, Nature not man is the adversary. Indeed, I saw that if a doctor wished he could always remain, and usefully so, in direct contact with the object of his endeavors: the sick man, woman, or child.
Spurred by the apprehensions of wartime and government tracts urging that doctors were sorely needed for service in the army, Castle enrolled at Harvard Medical School at the end of his third year of college as a member of the class of 1921. His impression while a student of the state of medical science at the time was expressed in comments made to me in 1978:
After reading the 1910 edition of Osler's textbook, I was impressed with how little could be done for the sick by doctors--other than surgeons, who had long had direct experimental experience. Most of the few specific medical remedies available at the time had been stumbled upon by primitives, witches, milkmaids, and sailors. I thought therefore that even I might have something to offer, either in research or surgery. As an initial step to either I sought a medical internship and was fortunate to be offered one at the Massachusetts General Hospital.
As a twenty-one-month house pupil at the "Old Massachusetts" from 1921 to 1923, Castle had his first direct exposure to some of the great clinicians of the time, including Chester M. Jones, with whom he collaborated in his first medical publication, and the meticulously observant George R. Minot,2 who later became Castle's mentor and unflagging supporter. Having made a favorable impression as a clinician, Castle was invited to continue on at the MGH, but his consuming interest remained in "finding out how things work," a passion fired by the great discovery of insulin by Banting and Best, announced in 1922 and applied in the nick of time at the MGH to save Dr. Minot from dying in diabetic coma. With this dramatic example of the raw potential in medical research, Castle could not envision a life of rushing up brownstone stairs to attend to indisposed Boston merchants. Instead, in 1923 he accepted a position in Cecil Drinker's laboratory at the Harvard School of Public Health. Reminiscing on this, he said:
I acquired a respect for accurate experimental protocol and for the private feelings of living tissue. . . . It was there too that I learned from Harold Himwich . . . the meaning of hard work while we investigated the a-v differences in oxygen and carbon dioxide of blood supplying an isolated dog gastrocnemius muscle while at rest. Its R.Q. was found to be 0.71, rather than unity as was then expected.3
These observations anticipated by over three decades general recognition that the primary source of energy for muscle was fatty acids, rather than glucose.
In 1925 Castle was enticed back into a clinical setting at the Thorndike Memorial Laboratory, Boston City Hospital, by the luminous Francis W. Peabody. A profoundly admired and gifted man and physician, Peabody had within several years attracted to the Thorndike a remarkable nucleus of talented young men destined soon to become leaders in academic medicine; these included Joseph Wearn, Perrin H. Long, Henry A. Jackson, Jr., Alberto A. Hurtado, Herrman Blumgart, Charles Doan, Chester Keefer, Soma Weiss, and the young Castle. Peabody retained a favorable impression of Castle gained several years earlier during the latter's third-year clinical clerkship. This came about, interestingly enough, because Castle had flunked the previous year's examination in hematology owing to an inability to count red cells. Peabody granted the flunkee an opportunity to redeem himself via an interview, and Castle's performance was sufficiently memorable to gain him an historic appointment. At this time Peabody was deeply interested in the cancer-like marrow morphology of pernicious anemia, and Castle assisted him in the collection of tibial marrow biopsy specimens obtained by surgeons employing mastoid trephines and cuvettes. Peabody took the slides to Northeast Harbor, Maine, during his escapes from administrative duties and described the specimens presciently as showing "inefficient erythropoiesis." Suddenly, the following year pernicious anemia became a focus of international attention, with Minot's stirring discovery that this dread, uniformly fatal ailment could be cured by feeding patients odious quantities (300 grams daily) of raw or lightly cooked liver. With Peabody's untimely death in 1927 and public awareness of Minot's pending arrival as his successor as director of the Thorndike, patients flocked to the City Hospital. Minot's grand achievement, which later earned him the Nobel Prize (shared with Whipple and Murphy), was an empirical consequence of his fastidious attention to strict dietary regimens and meticulous reliance on reticulocyte levels as a quotidian measure of therapeutic response. But Minot, a nineteenth-century prototype, was scientifically unprepared to pursue his great discovery. Castle's mechanistic mentality was perfect for grappling with this lingering riddle: If normal people do not have to eat any liver to maintain normal blood counts, why should ingestion of liver in large quantity cure pernicious anemia?
In the fall of 1927 Minot was scheduled to give an address before the American Academy of Arts and Sciences in Boston to present the latest bulletins on the new therapy of pernicious anemia. Apprehensive as to how Minot would look upon his uneventful first two years at the Thorndike, Castle attended the talk. While descending to the ground floor of the Thorndike via the back elevator en route to Minot's lecture, Castle experienced a flash of insight. If it was true, as had been recorded most convincingly by S. A. Levine and W. S. Ladd, that all pernicious anemia patients lack gastric juice, the trouble must be that--deprived of effective digestion in their stomachs--they were unable to "make" their own liver extract. The essentials of Castle's experiments to explore this fanciful thought were deceptively simple. Castle, who slept in a room next door to the Thorndike ward kitchen, resolutely fed himself 300 grams of raw beef patties every morning while in fasting state and after one hour induced regurgitation by pharyngeal stimulation. The captured semiliquid contents were adjusted to pH 2.5 to 3.5 with HCl and incubated for six hours at body temperature, after which the liquefied material was passed through a fine sieve and neutralized before introduction via Rehfuss tube into the stomach of the unwitting patient. Patients who were unresponsive to beef muscle alone (or to gastric juice alone) showed brisk reticulocyte responses when this sour admixture of predigested beef muscle was administered. These indelicate but "classic" studies were amplified and confirmed in every conceivable way in a series of fifteen papers bearing the heraldic banner, "Observations on the Etiologic Relationship of Achylia Gastrica to Pernicious Anemia." In the fifth paper (1936) of this memorable series, Castle and T. Hale Ham summed up experiments performed in sixty-one consecutive cases, and silenced critics of the Castle hypothesis, in a succinct synopsis of their long labors:
If beef muscle and gastric juice are administered without opportunity for contact, they are not effective. It is obvious, therefore, that the activity of mixtures of beef muscle and gastric juice cannot be due to the simple addition of two subthreshold substances but requires an interaction between them.
Castle called the essential gastric secretion "intrinsic factor" because it was formed in the body and could not at the time be chemically identified. Indeed, it was not until the 1970s that the primary structure of this essential glycoprotein secreted by gastric parietal cells was elucidated. In the tenth paper of the "Observations" series, published in 1948, Castle and associates showed by therapeutic trial (in a study confirmed independently by Randolph West) that "extrinsic factor" was identical to the B vitamin now known as cobalamin, which had been purified earlier that year by Karl Folkers's group and by E. L. Smith and L. F. J. Parker on the cis and trans sides of the Atlantic. This was capped off by Dorothy Hodgkin's three-dimensional crystallographic analysis of cobalamin structure in 1956, for which she received the Nobel Prize in chemistry in 1964.
It became clear in retrospect that Castle's seminal experiments had been correct in targeting an interplay between intrinsic and extrinsic factors and in identifying extrinsic factor as a B vitamin, but he had not pinpointed the role of intrinsic factor as an intestinal transport vehicle for this essential nutrient. Nonetheless, Castle's series of papers established for the first time that nutritional deficiencies can result not only from defective diets but also from faulty absorption or metabolism of nutrients. The latter mechanisms Castle grouped together as "conditioned deficiencies." Pernicious anemia, in his words, was a form of "starvation in the midst of plenty."
In the present time, when clinical observation is tightly regulated by public agencies and strict human studies' protocols, it is unlikely that Castle's benign but covert experiments would pass muster. It would, indeed, be an interesting fantasy to listen in as Castle, with his flare for euphemism, explained his regurgitation studies to round-eyed patients gripping consent forms. When he submitted his initial studies of intrinsic factor to the Warren Triennial Prize Committee at the MGH in 1928, Castle was bound by rules requiring anonymity. He identified his winning entry with the regal disclaimer, "Honi soit qui mal y pense." In a larger view, taken by Yale University when in 1933 it conferred on Castle his first honorary degree, Professor Phelps commented on both the brilliance and heroism of the awardee, adding that "Prometheus showed no greater self-command."4
After affirming and extending his studies of intrinsic factor, Castle wasted no time in attempting to prepare an injectable form of liver extract containing the active ingredient. Minot and the physical chemist Edward J. Cohn were engaged in systematically fractionating liver using heat, alcohol, and acidification and came up with an effective oral preparation that reduced the daily requirement from 300 grams of liver to about 12.5 grams of yellow powder ("fraction G"). Knowing from Cohn's work that the active factor was not a protein, Castle minced up liver in capacious crucibles, added water, boiled his brew, stirred it with paddles, and strained off the strange soup through cheesecloth. From this crude beginning, with simple modifications, Castle and F. H. Laskey Taylor produced a "domestic liver extract" that could be injected safely either intramuscularly or (given slowly) intravenously. This discovery was not only of great practical merit but also led to the provocative finding that the protein-free, water-soluble principle was far more potent, unit for unit, when given parenterally than when taken orally.
Stimulated by George C. Shattuck and aided by his influence in the field of tropical diseases, Castle in 1931 enlisted the interest of the Rockefeller Foundation in underwriting an expedition to Puerto Rico to assess the efficacy of his liver extract in patients with tropical sprue. Under Rockefeller auspices, an entourage consisting of Castle, Cornelius P. (Dusty) Rhoads, and a group of assistants set sail for this subtropical island, which at that time was no paradise, for a majority of its citizens were laid low by the coendemic ravages of tropical sprue and hookworm-induced anemia. At the Presbyterian Hospital in San Juan, in which their laboratories were located, Castle and Rhoads were at first fascinated by the rich aromas borne by the breeze, "a nostalgic mixture once you have breathed it--compounded of the smell of moist humus and humanity, burning coconut husks, and a trace of ginger. . . . On a nearby beach . . . deep blue shoaled to bright green towards the yellow sand gently fingered by the moving shadows of palm fronds. . . ."5
But there were also darker shadows and the hovering stench of sickness caused by tropical sprue, a dispiriting disease endemic to this island. Tropical sprue patients had megaloblastic anemia and severe glossitis similar to that of untreated pernicious anemia, but these patients failed to respond to oral liver extract or to combinations of beef muscle and normal gastric juice. Furthermore, many of them had ample amounts of acid gastric juice, which contained normal concentrations of intrinsic factor, as determined with the "human reticulocyte assay" performed on frozen specimens mailed to the expedition's anchor man in Boston, Maurice B. Strauss. In the treatment of sprue, Castle's home-brewed parenteral liver extract paid off wonderfully, patients responded promptly, and the debilitating anemia of sprue was established as resulting from "intestinal impermeability," later referred to as malabsorption syndrome. The pathogenetic mechanisms responsible for initiating tropical sprue, and its curiously spotty distribution, still have no tidy explanation, but since the Castle-Rhoads expedition empirical prophylaxes with folate and cobalamin have eradicated this melancholy menace in Puerto Rico.
While contending with tropical sprue, Castle, Rhoads, and company confirmed B. K. Ashford's observation that 90 percent of the island population was infected with hookworm. Vermifuges expelled the worms and stopped intestinal bleeding, but hematologic responses were uneven and subject to relapses attributed to obscure wormborne toxicities. Blood morphology was identical to that of the iron deficiency characteristic of bleeding Bostonians. Both in the hospital and in the small cooperative town of Cidra, Castle's group showed that removing hookworms from anemic patients did nothing to improve hemoglobin levels, but that iron induced a rapid rise whether or not hookworms were removed. With a characteristic canny blend of logic and social pragmatism, Castle convinced public health authorities that their emphasis on priority for purging parasites was not as sensible as a direct attack on the anemia. Hematologic remissions he recounted ". . . would quickly restore subjective health and return the patient to work. He could then learn the value of a better diet and could build a latrine in the backyard, buy shoes, and have his worms eliminated without the likelihood of recurrence." For his contributions to the well-being of Puerto Ricans, Castle was awarded the key to the city of San Juan.
Castle's interest in pernicious anemia and other megaloblastic anemias persisted throughout his lifetime, engendering scores of papers dealing with assays of liver extracts; identification of cobalamin (vitamin B12) with "extrinsic factor"; recognition that pernicious anemia of pregnancy responded to a different vitamin, later identified as folate; interactions between folate and ascorbate; and the mechanisms of absorption and metabolism of pteroylpolyglutamates. When receiving the Kober Medal, Castle reminisced that he had been privileged to experience several great moments of insight and promise for the future. Foremost among these were the appearance of the first reticulocyte response in pernicious anemia to autodigested beef muscle, the dramatic improvement in tropical sprue induced by parenteral liver extract, and the startling increase in viscosity of deoxygenated sickle cell anemia blood that he and T. Hale Ham first witnessed.
One afternoon in the late 1930s Castle and Ham were methodically observing the effects on red cell volume of changes in O2 and CO2 tensions. Among the several varieties of hemolytic anemia blood so studied was that from a patient with sickle cell anemia. As he recalled it later, "We discovered that when the pCO2 was held constant, and the pO2 was lowered in one sealed tube and not the other, deoxygenated sickle blood failed to sediment in the centrifuge. It immediately occurred to us that this was because the elongated, sickled red cells had become tangled up 'like haywire.'"
From this Ham and Castle deduced a general theme that stagnation ("erythrostasis") and packing ("erythroconcentra-tion") of red cells were primary mechanisms in many kinds of hemolytic anemias, including hereditary spherocytosis (HS) and possibly immunohemolytic anemias. The genetically defective cells of HS were shown by Castle, Ham, Charles P. Emerson, Jr., and their associates to lose control of volume, shape, and surface area when subjected to erythrostasis for long periods in vitro, unless the cells were repeatedly reinvigorated by additions of glucose or fresh serum. The vulnerability of these cells to packing and substrate depletion led to origination of the "incubation fragility test." More importantly, spherocytosis and cell membrane loss observed in vitro during erythrostasis and erythroconcentration were shown to correspond with changes in red cells recovered from blood and spleens of patients with HS; this both defined the essential role of splenic vasculature in expressing the latent cell defect and explained the efficacy of splenectomy in curing the anemia despite persistence of the membrane abnormality. These observations, first recorded in general and in abstract form by Ham and Castle in 1940, had a profound influence on the direction of research on nonimmune mechanisms of hemolytic anemias in the late 1940s, although publication of the full body of experimental evidence and clinical specifics (gathered mainly by C. P. Emerson) was delayed by a Darwinian sixteen years.
The potential for hematologic havoc through erythrostasis was most grippingly evident in sickle cell disease. Using the Ostwald viscosimeter and sealed cylindrical flasks containing blood equilibrated with gas mixtures, Ham and Castle observed in 1940 that reduction of PO2 to levels approximating that of mixed venous blood dramatically increased the viscosity of sickle cell (but not normal) blood. This led to Castle's famed postulation that the painful crisis, organ infarcts, and hemolytic anemia of sickle cell disease were the consequence of a vicious cycle initiated by increased viscosity, the endpoint being vascular occlusion by ensnarled rigidified red cells. This 1940 interpretation of events at the cellular level took wing in 1945 during a legendary conversation between Castle and Linus Pauling, as they traveled together by overnight train from Denver to Chicago. As recorded by Castle's former colleague in megaloblastic matters, M. B. Strauss,6 Castle sketched out to Pauling some of the work he and Ham had been doing since 1940 on sickle cell disease, adding that ". . . as stated by Dr. I. J. Sherman in 1940, when the cells were deoxygenated and sickled they showed birefringence in polarized light. This, I stated, meant to me some type of molecular alignment or orientation, and ventured to suggest that this might be 'the kind of thing in which he would be interested.'"
It was indeed the kind of thing, for in the following year, Pauling, Harvey A. Itano, and others began studies using moving boundary electrophoresis that showed sickle cell hemoglobin to be intrinsically abnormal in its electrophoretic migration. The report7 of this finding ushered the age of molecular biology into clinical medicine. Knowledge of the discovery by Pauling's group inspired John W. Harris, then a fellow of Castle, to investigate the physical properties of sickle cell hemoglobin solutions divested of cell membranes. When sufficiently concentrated, deoxyhemoglobin S was shown by Harris using phase optics to form long, watery crystals or tactoids;8 these rigid and birefringent bodies, created by cable-like growth of filaments of polymerized hemoglobin S, account for the vascular impactions by sickled cells. Our elaborate knowledge today of the molecular biology and pathogenesis of sickle cell anemia stems directly from Castle's bold inference based on viscosity plus birefringence.
The Minot-Castle era of hematology research began before hematology had become a business. It started with W. C. Townsend, M. B. Strauss, C. W. Heath, J. H. Burchenal, R. W. Heinle, and F. H. Laskey Taylor, a gifted group of investigators who overlapped with T. Hale Ham, followed by P. F. Wagley, J. Watson, F. H. Gardner, and C. P. Emerson, Jr. Castle's first generation of trainees, which included several of these, ended with the departure in the early 1950s of Ham, J. W. Harris, Robert F. Schilling (author of the Schilling test), S. C. Shen, and others schooled by Castle in learning from the "mistakes of nature." Clearly, Thorndike hematology under Castle was immensely productive but physically restricted, forcing newly spawned investigators to swim off to less crowded waters, where their activities could be amplified. Consequently, a brief lull in scientific productivity set in, occasioned in part by Castle's increasing administrative responsibilities. Progressively hampered by complications of diabetes, Minot had gradually transferred the reins of office to Castle during the 1940s, a process made official by Castle's appointment as director in 1948.
Thorndike tradition had strongly nurtured a do-it-yourself philosophy, often placing outrageous demands on the investigator, and Castle and his chancellor of the exchequer, Maxwell Finland, kept a keen watch on the number and quality of incoming fellows and the resources grudgingly allotted them. In 1952 hematology was represented by only three fledgling fellows (M. S. Greenberg, J. H. Jandl, and A. A. Lear), and Castle was seldom at liberty to roam the laboratories or fuss with the various gadgets, such as the mechanical fragility machine, which he had invented, assembled, and hitherto kept in good repair. Nevertheless, those of us starting then were peculiarly fortunate, for while we spent most of our time learning the techniques of science the hard way, we were repaid for our labors by access to frequent, informal conferences with this legendary man, who treated us all as his intellectual equals.
Associating with Castle, exchanging ideas, debating data, absorbing tactful corrections, and learning to search the entire natural universe if necessary for clues to disease processes challenged every neuron in our bodies. Castle's curiosity was insatiable, his mind was never idle, and it seemed almost impossible to get enough of him. He conveyed the power to think more clearly, observe more sharply, and function more effectively than we ever had on our own. I think this was because he could see in us potentials we did not know we had. Certainly his incorruptible example served as our gold meter bar, by which we could measure ourselves and direct our endeavors. If Castle had approved our experiments and interpretations, we felt no nervousness whatever on reporting them before national societies. Soon to share in this heady atmosphere was Allan J. Erslev and, on an informal basis, Rudi Schmid. Castle's preoccupation with the mechanisms of anemias (rather than further development of their remedies) led him to sustain his lifelong interest in pernicious anemia and allied processes. Under his benign direction, experimental observations were resumed through the efforts of a succession of colleagues, including Bernard A. Cooper, Hendrick O. Nieweg, and later Victor Herbert; Herbert in turn shared the responsibilities of training and collaborating with Louis W. Sullivan, Ralph Zalusky, and Richard R. Streiff. Jandl and co-workers already had launched a broad attack on the mechanisms of hemolytic anemias, bearing out many of the predictions made earlier by Ham and Castle, and then conducted increasingly independent studies that among other things defined the role of Fc receptors in immune hemolysis and demonstrated the existence of transferrin receptors. With characteristic magnanimity, Castle transferred responsibility for the hematology division to Jandl in 1962, and the following year stepped aside as Minot Professor and director of the Thorndike enabling Finland to take on these titles and duties in recognition of his extraordinary contributions in funding and remodeling the aging facility. These maneuvers, involving Castle's appointment as Francis Weld Peabody Faculty Professor of Medicine, led to a second generation of Castle fellows, his scientific grandchildren. Jandl ran the division under Castle's sparkling firmament. From this lively and collegial arrangement spilled forth a remarkable new crop of talented investigators, all of whom became doyens in hematology or deans of medicine: David W. Allen, Harry S. Jacob, Manuel E. Kaplan, Richard H. Aster, H. Franklin Bunn, Christian Gulbrandsen, Richard A. Cooper, Herman A. Godwin, Albert F. LoBuglio, Neil Abramson, and Sanford J. Shattil.
In 1968 the hard rules of retirement then in force had already been stretched by five years in Castle's case through his appointment as faculty professor. Castle's own mental faculties at this time had remained so much livelier than those of most younger colleagues that it was unthinkable to let him go. Through the collusion of benevolent admirers Castle was appointed distinguished physician by the Veterans Administration and assigned to the West Roxbury V.A. Hospital. Here he was welcomed by old friends (T. A. Warthin and R. P. Stetson) and stirred excitement and strong loyalties among the young staff and residents of that hospital and of members of the Brigham and Women's Hospital staff who rotated through this V.A. affiliate. As he had done at the Boston City Hospital, Castle soon imbued the staff of the West Roxbury V.A. Hospital with his view that in both patient care and research the patient is the essential analyzer and the clinical investigator should never abandon the unique, often heuristic, experiences arising during direct patient care. Castle resigned as distinguished professor to become senior physician at West Roxbury V.A. Hospital in 1972, and for several years thereafter he conducted regular tutorial sessions, clinic rounds, and conferences in hematology. After Harvard's withdrawal from Boston City Hospital in 1974, the epicenter of the Castle mystique shifted back to Harvard Medical School, where one of the four educational pathways (programs) was designated the William B. Castle Society.
Honors came to Castle early on as well as late. He received nine honorary degrees, fifteen honorary memberships, and two dozen special awards, including the Walter Reed, Leonard Wood, and George Kober medals. Conferrers of awards were usually rewarded in return by the felicitous phrasing characteristic of Castle's speech. In addressing a prestigious gathering of gastroenterologists in 1959, he explained that, "The human stomach is a convenient receptacle for food in both savage and civilized man who, for quite different reasons, must often eat and run."
Physically, Castle was tall and angular, moved about restlessly, and gestured with long sinewy arms and spidery but powerful hands. His deep, penetrating voice imparted authority, and his leveled eyes held their focus attentively on the subject or person at hand. However impatient with interruptions by telephones and by the impositions of administrative persons, whom he classified collectively as "chrono-phages," Castle was always generous with his time in discussing scientific matters with colleagues. This was for him a pleasure, not a duty--or perhaps deep in his good-natured and conscientious soul, helping out on research problems, like lending a hand, was a pleasurable duty. Long after official retirement, while at home or when attending rounds, seminars, or scientific programs (many of which were held in his honor by various generations of the "Castle family"), his astute comments and biological or philosophical excursions invariably added sparkle as well as insight.
Castle's facility with words added immeasurably to the impact of his written and spoken thoughts, which nearly always contained one or more graceful phrases lastingly treasured in the memories of rapt listeners. This gift not only enabled him to link human values to dry facts but served to deflect and neutralize those awkward moments or phrases incidental to human intercourse. When a visiting dignitary holding forth on grand rounds once expressed patronizing amazement that "such splendid science was being conducted here--at the Boston City Hospital," Castle uncoiled slowly to his feet during the dead silence to remark in his deep rumbling tones, "at last Mohammed has come to the mountain." This gift for recasting adversity was his first weapon of defense when expenditures loomed, for the generosity of the great man was equaled only by his parsimony. For him the most pleasurable of all situations occurred when resourcefulness could be substituted for expense. When in the 1950s impecunity forced me to make periodic demands for incremental levels of support, my requests were received with visible agitation, followed by a well-paced stream of anguished propaganda that issued forth for weeks. After dropping handbills in my letterbox advertising $7 pants and $3 shirts, and then extolling the thrift of powdered milk as a solution available to the impecunious, Castle's final stratagem on one occasion was to send me a copy of a communication from Francis Peabody written in 1925. In this letter Castle was offered a stipend of $1,000 per year; on the margin he penned the words, "As are you, Jim, so once was I." Frugality and abhorrence of waste were ironed into his soul, but with the resources possessed by him--his scientific instincts, his language skills, use of his aged cars, the summer house he and Louise made available to friends and fellows--with these he was always generous. For years the Castles offered to our enlarging family vacation use of their spacious home on the Cape. An annual preliminary ceremony was the vernal installation of their dock, a process Castle preferred to perform personally. Among the most unnerving experiences of memory was that of standing on the cross-member of a sawhorse, wielding a 16-pound maul to drive in the vertical posts grasped beneath me by Castle, neck-deep in river water. On one occasion I hesitated while apprehensively studying the famous but fragile cranium below, spaced inches from the post. "Anything wrong?" he asked. "No, just shifting my position." His smiling response left me dumbfounded. "I thought perhaps you were pondering the future directorship of the Thorndike!" After sweaty tasks of this kind, we generally cooled off in the river and then resumed discussions of how skunk cabbages melt their way through hard ice or other mysteries of nature that invited exploration.
For anyone with broad interests in the external world (Castle had no use for introspection and almost none for psychiatry), his panoramic appraisals of "all the uses of this world" were astute and fearless. As recorded by his son, William Rogers Castle,9 he wanted to know, after reading a few pages of Portrait of the Artist as a Young Man, whether Joyce suffered from eye disease. "I thought so," he said; "there was all that emphasis on losing his glasses." A naturalist by habit, he was irked by Thoreau for "misidentifying a few birds in his nature writing." Castle loved steam engines both for their working parts and for their efficiency in transporting people in a state of productive privacy and was outraged at the dismemberment of railroads by financiers. He once burst into the lab exclaiming that it no longer was possible to go by train from Boston to Cincinnati. He feared and disapproved of airplanes, especially the supersonic Concorde, and brooded over the inequity of a privileged few gaining dubious minutes while we earthlings lost our hearing.
Castle's sharp eye for particulars and gift of insight remained with him until his final days. Thanks to the indispensable and inspiring efforts of his remarkable wife, Louise Muller Castle, to whom he had been married since 1933, and with encouragement from their daughter, Ann Castle Morris, and son, Castle was able to receive a procession of friends and colleagues until the week of his death. Visitors made pilgrimages to the venerable Victorian edifice at 22 Irving Street more to receive than to give. Time spent with Castle, even as congestive heart failure shortened his sentences (but not his wits or comprehension), continued to be an adventure. As recently as 1988 he journeyed to the medical school to participate with characteristic zest and nimble humor in a special hematology research session convened by H. F. Bunn. Then, as throughout his long life, William Castle was stimulating, original, inquisitive, tactful, humorous, courtly, considerate, and constantly interesting. One could never get enough of his company. That company we shall forever miss.
I AM INDEBTED TO Elin and Richard Wolfe of the Countway Library, the late Lillian Blacker of the Harvard Medical Area News Office, and John W. Harris of Case Western Reserve University for help in collecting source material. Most of the uncredited quotations were based on written or taped transcripts of informal conversations with me that took place during the 1970s.
1 William E. Castle, 1867-1962. In Biographical Memoirs, vol. 38. (New York: Columbia University Press for the National Academy of Sciences):33-80.
2 George R. Minot, 1885-1950. In Biographical Memoirs, vol. 45. (Washington, D.C.: National Academy Press):337-83.
3 W. B. Castle. Acceptance of the Kober Medal award for 1962. Transactions of the Association of American Physicians. 75(1962):54-58.
4 Yale Alumni Weekly 42(July 7, 1933):786.
5 W. B. Castle. Some contributions of the tropics to general medicine. In Industry and Tropical Health V. Published for the Industrial Council for Tropical Health by the Harvard School of Public Health (1964):56-64.
6 M. B. Strauss. Of medicine, men, and molecules: Wedlock or divorce. Medicine 43(1964):619-24.
7 L. Pauling, H. A. Itano, S. J. Singer, and I. C. Wells. Sickle-cell anemia, a molecular disease. Science 110(1949):543.
8 J. W. Harris. Studies on the destruction of red blood cells. VIII. Molecular orientation in sickle cell hemoglobin solutions. Proceedings of the Society for Experimental Biology and Medicine 75(1950):197.
9 W. R. Castle. Harvard Medical Alumni Bulletin 64(1991):18-19.


text:
'); } -->
HOUSEKEEPING & JANITORIAL: SOTO'S HOUSE CLEANING Weekly, every 2 weeks, monthly, one time only: cleaning, inside and outside, free estimates. (559)908-3848More info Email a friend
CONSTRUCTION SERVICES: D.E. Hartesveldt Construction General Contractor Improving homes for over 25 years. Specializing in: Kitchen and bath remodels, Room additions, decks, repairs and appliance installations. CA Lic. #475909 (559)760-4976More info Email a friend
CONSTRUCTION SERVICES: DON'T MOVE IMPROVE! K&E Construction All phases of construction No job too small. Since 1975 CA Lic. #307444 683-4171 or 287-5528More info Email a friend
LANDSCAPING & YARD WORK: WE HAUL IT ALL. Yard cleaning, weed eating, brush clearing, gardening service. We'll haul your garbage, scrap metal, green waste. Ref. upon request. Sandro (559)760-0660.More info Email a friend
LANDSCAPING & YARD WORK: WEEDEATING Call for free estimate. 689-3527 - 676-0316More info Email a friend
LANDSCAPING & YARD WORK: ~~GIDDY UP AprMore info Email a friend
HOUSEKEEPING & JANITORIAL: ATTENTION COARSEGOLD! Housecleaning. Dependable and honest, one time or regular service, 3 hours/$45. Call (559)676-9461More info Email a friend
HOUSEKEEPING & JANITORIAL: HOUSE CLEANING - 20+ yrs. exp., great refs., dependable, consistent, detail oriented & honest. 1 time or regular service. 3 Hrs. @ $60. 683-2265.More info Email a friend
DRY WALL & TEXTURE: ALL PHASES of drywall, hands on, tape, texture, accoustical removal, big or small jobs. Guaranteed. Reliable. CA Lic.#403348 (559)905-6497More info Email a friend
CEMENT WORK: WDF CONCRETE Construction, we do all concrete, walkways, driveways, patios, stamped, colored. Free estimates, CA. lic. #933240. Call (559)908-1891.More info Email a friend


text:
Reno >Home & Garden > Mor Furniture For Less
2212 Harvard Way, Reno, NV | Directions 8950239.502683 -119.785795
Monday - Saturday 10:00 - 9:00
Sunday 10:00 - 8:00
Neighborhoods: Ward 2
Sign in with Facebook Sign in with Facebook to see what your friends are up to!
Do you have a review of Mor Furniture For Less on your blog? If you include the Citysearch image link (shown below) in your post, we'll automatically link to your review from the business profile page. Here's how our Linkback system works:
The Linkback system is free and automatic. It's really that easy.
To link to our business profile page, copy the html below to your web page.


text:
See the biggest names in music take the stage at Orlando's premier performance venue...the Coliseum of Rock 'n' Roll.
Rating -
Obviously your enjoyment depends on the band playing. The venue is well laid out and offers great views of the stage!
Have you been to Hard Rock Live® Orlando?
"No spam, no mailing lists! Personally identifiable information is never sold, shared or leased to any other parties"
© 2010 BMP. Bubba Gump Shrimp Co. ™ & © 2010 Par. Pic. ™ & © 2010 Burger King Corporation. All Rights Reserved. © 2010 Cinnabon, Inc. All Rights Reserved. Cinnabon®, the Cinnabon Logo, Minibon® and Caramel Pecanbon® are trademarks of Cinnabon, Inc. Emeril's ® Emeril Lagasse. Fossil ® Fossil, Inc. Hard Rock Cafe, Hard Rock Live ® Hard Rock Cafe International (USA), Inc. Hart & Huntington Tattoo Company ® Hart and Huntington LLC. All rights reserved. Jimmy Buffett's ® Margaritaville ® Jimmy Buffett. Latin Quarter ™ Latin Quarter Entertainment, Inc. NASCAR®, NASCAR Sports Grille ™ are trademarks of NASCAR, Inc. NASCAR®, NASCAR Sports Grille ™ are trademarks of the National Association for Stock Car Auto Racing, Inc. © 2010 Moe's Franchisor LLC. All Rights Reserved. Moe's Southwest Grill® and the Moe's Round Logo are trademarks of Moe's Franchisor LLC. © 2010 Panda Restaurant Group, Inc. All Rights Reserved. Pat O'Brien's, Hurricane Glass logo, Have Fun! and Iron Grill Design ® Pat O'Brien's Bar, Inc. © 2010 Pat O'Brien's Bar, Inc. All rights reserved. Quiet Flight ® Quiet Flight Surf Shop, Inc. © 2010 Starbucks Coffee Company. All rights reserved. TCBY® is a registered trademark of TCBY Systems, LLC. The Endangered Species Store ® Kupono Investment, Inc. Universal elements and all related indicia ™ & © 2010 Universal Studios. All rights reserved.
AMC Universal Cineplex 20 with IMAX® Big Kahuna Pizza Blue Man Group Bob Marley - A Tribute to Freedom℠ Bubba Gump Shrimp Co.™ Restaurant & Market Cinnabon® CityWalk Arcade CityWalk's Rising Star Emeril's® Restaurant Orlando Fat Tuesday Fossil® Fusion Bistro Sushi & Sake Bar Galaxy Bar Hard Rock Café® Orlando Hard Rock Live® Orlando Hart & Huntington Tattoo Company® Jimmy Buffett's® Margaritaville® Latin Quarter Lone Palm Airport Moe's Southwest Grill NASCAR Sports Grill℠ NBA City Panda Express Pastamoré℠ Pat O'Brien's® Orlando Quiet Flight® Surf Shop Starbucks® Coffee TCBY® The Endangered Species Store® The groove℠ Universal Studios Store® Whopper™ Bar


text:
is mentioned only three times in the Bible, and on each occasion under a different name in the Hebrew. (1 Samuel 17:18; 2 Samuel 17:29; Job 10:10) It is difficult to decide how far these terms correspond with our notion of cheese, for they simply express various degrees of coagulation. Cheese is not at the present day common among the Bedouin Arabs, butter being decidedly preferred; but there is a substance closely corresponding to those mentioned in 1Sam 17, 2Sam 17, consisting of coagulated buttermilk, which is dried until it become quite hard, and is then ground; the Arabs eat it mixed with butter.
SearchEnter the Bible passage (e.g., John 3:16), keyword (e.g., Jesus, prophet, etc.) or topic (e.g., salvation)
Resources » Smith's Bible Names Dictionary » C » Cheese


text:
Narrow your search
As lethal protests wrack the country, the government becomes more heavy-handed with censorship.
A study finds that video games may cause aggressive behaviour, but the trigger isn't violent content, it's frustration.
Star investor Ron Conway is among those behind a series of $1 million challenges aimed at using technology to improve gun safety. The key? Find ways to make sure only guns' owners are able to fire them.
Following the tragedy in Newtown, a group of entrepreneurs led by Ron Conway resolved to use technology to help stem gun violence. Their debut effort is an incentive challenge to create smarter, safer firearms.
After an activist campaign and advertiser boycott, the social network deems any content that glorifies rape or domestic violence as hate speech.
In concert with the Sandy Hook Promise Technology Committee to Reduce Gun Violence, the tech investor community is working to find and fund technology to reduce gun violence.
The Australian Government's Classification Board, which determines ratings on video games and decides if they can be sold in the country, lays down the ruling.
Following the fatal gang rape of a 23-year-old and subsequent calls for better protection of Indian women, the government proposes a gadget that would alert police, send GPS coordinates.