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Geo Maze Needlepoint Pillow Cover
- Summary
An architectural motif found around the world and throughout history makes this pillow cover an exceptionally versatile accent. Hundreds of fine, hand-worked needlepoint stitches lend the design great texture and depth.
- Cotton base fabric hand-embroidered in wool on the front.
- Backed and piped in solid ivory cotton.
- Hidden zipper.
- Insert sold separately.
- 18" sq.
- Dimensions & More Info
Made in China.
- Use & Care
Spot clean with a damp cloth, blot to remove excess water, air dry.
- Shipping
Shipping Information
This item is shipped from our warehouse by UPS to arrive within five business days of our receiving your order.
Shipping Rates
The shipping rate varies depending on your order total and shipping destination. View Shipping Options and Charges.
Rush Delivery
For an additional charge of $15 per address, we can rush delivery to most destinations. This service is not available for some oversize items, items shipped directly from the supplier (including perishable and custom-manufactured items), out-of-stock items and items to be shipped outside the contiguous 48 states.
Return Policy
At Williams-Sonoma, we take great pride in the quality and craftsmanship of our products. If, within 30 days, you are not completely satisfied with your purchase for any reason, please return the item for an exchange or refund of the merchandise value. View Full Return Policy.


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Designer Ross Lovegrove expounds his philosophy of "fat-free" design and offers insight into several of his extraordinary products, including the Ty Nant water bottle and the Go chair.
pin This talk was presented at an official TED conference, and was featured by our editors on the home page.
- Interactive transcript (20 languages)
155 comments
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For more than three decades Sherrod Vans has been known as the premier designer and manufacturer of custom conversion vans. Managed by its original owner, Jack Sherrod, Sherrod Vans continues to provide a uniquely designed conversion van, tailored to both the driver and passengers, and which is backed up by its quality warranty and service department. Mr. Sherrod's name and reputation is on each and every vehicle.
The Sherrod Van product line consists of conversion vans, muscle cars, and mobility compatible vans. Our vans are multipurpose, satisfying the needs any customer, from a mobile office to pure luxury touring. Regardless of your individual requirement, all our design concepts emerge from "luxury," and the interior of our vans mirror the level of detail, design and comfort which are usually only experienced in luxury yachts and private aircraft.In addition, with a Sherrod Van, you can "stay connected" with all of your home audio, video, computer and communication devices, through wi-fi compatibility and our game control center.
Sherrod Vans does not "outsource" it manufacturing. The Sherrod 73,000 square foot headquarters in Waycross, Georgia houses Research and Development, Quality Assurance, Manufacturing and Customer Service. The Sherrod commitment to quality of product remains unsurpassed, and all of the manufacturing processes are meticulously reviewed by Quality Engineers to insure that performance is not sacrificed in the name of luxury and comfort.
Regardless of your needs: professional, client services, meet and greet, or just pure luxury touring, from short hauls to long hauls, there is no equivalent to the Sherrod Van experience when it comes to safety, comfort, performance, and luxury.
In addition, for those requiring mobility accessible compatibility, all Sherrod features are completely suitable to mobility conversion with all certified mobility devices.
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Wineries >Domaine Chandon Winery
1 California Dr, Yountville, CA | Directions 9459938.397400 -122.360005
Daily 10am-5pm
Skip it! – Skip this winery. We've always found Chandon's sparkling wines average at best, but we decided to stop by and see if the winery had some reserves or something special in their tasting room that might change our mind. Instead we had a young man serving us who couldn 't care less about telling us about what we were sampling, it was almost as if we were bothering him. Contrary to Napa's reputation of often having some smug hosts working their winery's tasting rooms, we found this the only winery in the area that had a terribly poor server. If you're young and into being hip and lounging around in a sterile tasting room that has the feel of a vegas hotel concierge lounge, then this is for you. They have some inexpensive wine and you can sit around with friends and milk a bottle over conversation. But if you are shopping for wine and would like an attentive host to tell you about what you are sampling, skip this place. Drive into the Carneros area and try Domaine Carneros. They'll treat you very well in a beautiful winery and their wine is much much better.
Best Sparkling Winery in the area – Chandon is the best Sparkling Winery in the area. The bar area is open and enjoyable, the staff is knowledeable about their wines. One of the best places to begin your wine tasting for the day. They have beautiful grounds and an excellent upscale restaurant. I would highly recommend tasting or dining at Chandon.
Worse winery tour in Napa Valley – In the twenty years of showing friends and family the Bay area, I've never been so remiss as this last weeks tour of this winery
The tour is a joke, no views of the bottling facility, nothing about the riddling process or view of the cellars, and the tour guide was un-informed to boot.
If spending 10 bucks for a 25 minute waste of time is your thing, then this is the place.
Do yourself a favor, go here for the wine but avoid the tour.
The wines are good and the oysters at the oyster bar are very good.
As long as you don't get "Meredith" leading your tour... – Unfortunately, when you spend $20 to get a tour at a winery, you expect to get your money's worth -- not listen to some bumbling just-out-of-college valley girl who spent last night getting plastered. The poor girl probably hadn't been working at the place for very long, but it was painfully obvious that she had no clue as to what she was talking about and was distractingly distracted by everything! She could barely finish her sentences without breaking into an excuse about why she was "out of it" and "spacing out" about the tour information. It seemed she should have been shadowing a more experienced tour guide, or if she wasn't new, should probably have been cut from the touring job already. At any rate, the tour was disappointing, since we heard such wonderful things about it prior to our visit; however, the tasting was great and our server was genial and informative. I think his name was Matt??? Anyway, good place to visit and do the tasting, but pass on the tour if you get anybody who seems inexperienced.
A secluded California estate where sparkling wines are made in the French tradition. – In Short
Dedicated to sustainable agriculture and making minimal impact on the land, Domaine Chandon is a smooth blend of Californian ideals and French tastes. The winery was founded in 1973 by European beverage conglomerate Moët-Hennessy and is recognized for its innovation in viticulture and adherence to the French tradition of sparkling wines.
Wine tasting in the middle of winter is amazing – My favorite beverage in the wine country is champagne so Domaine Chandon is heavenly for me. Ive dined at the restaurant for lunch on a number of occasions as a guest of my host so I am unfamiliar with the service charge mentioned in the other reviews, however the service has always been impeccable so I dont doubt that the staff deserves to be tipped accordingly. As for the dining room experience, even though the summers can be uncomfortably warm Ive been surprised that while dining al fresco we have always been very comfortable. The view is different than other wineries, but it is aesthetically pleasing even if it doesnt offer grand vistas of vineyards. My most memorable moments in the wine country have occurred here, not in the dining room, but in the tasting room, during the middle of winter in the very off-off season, mid-week. The people who pour have always been very friendly and accommodating and the experience, along with a flight of champagne, makes even the most overcast and dreary day pleasant.
Food missed expectations – Nice dining room. The ceiling was designed to look like you are inside of an oak barrel. The walk from the parking lot to the restaurant is very pleasant. The view from the dining room however, only looks out onto a small lawn. Don't you think a restaurant at a winery should look out at the vineyard?? Service here is white glove. The maitre d watches over the dining room like a hawk and the moment you run out of something or finish a plate he has someone spring immediately into action - this is not an exaggeration. The menu is quite limited. A few appetizers and a few entrees, or a prix fixe meal. We opted for the regular menu which proved to be awfully bland for a place of this caliber. I asked the waiter to suggest a bottle of sparkling wine that would pair well with our entrees - what a surprise - with all the ones on the list he picked the most expensive one. When I asked if he had a less expensive second choice he actually said this was the only sparkling wine that would work! The hard upsell was annoying. Mostly because of the food, this place is only a slightly above average dining experience.
Rude staff, mediocre food, huge checks. Awful. – I enjoy dining out regularly and have enjoyed meals at restaurants all over the world. This restaurant, however, was possibly the worst experience I have ever undergone. The service was cold, patronizing and borderline rude, we were hurried to finish each plate of the tasting menu. Even for a tasting menu, the portions were both insultingly tiny and of mediocre quality. The 'so-called' matching wines were equally small. The only thing huge was the check. Accompanied by tax and an automatic unannounced 20% service charge, it was nearly $400 for the two of us. There was nothing about the experience to recommend it. Not only will I not visit this place again I could not in all conscience recommend it to anybody other than my worst enemy.
Lovely place to visit with someone you love. – I enjoyed this little escape to heaven. The sparkling wine was by far the best around! Our waitress was full of info and on her toes. I liked the dessert & desert wine. The poached filet was not to good, it stole the flavor from the meat. Maybe add a couple of traditional entrees with the exotics, for the picky eaters. :) That would be the only thing! Everything was so enjoyable! Romantic...We will be back for sure.
beautiful setting – The long walkway that leads to the restaurant is absolutely breath-taking, although inconvenient. The restaurant itself glows with warmth and is very roomy. I found the menu quite small, but every dish was executed very well. The Chanterelle mushrooms were light and tasty, but I found the appetizers far more interesting than the entrees. And when did restaurants begin including a 20% service charge regardless of party size? I don't mind tipping well, but I've never encountered such a practice before. Our service was pleasant, but a bit inattentive. The crowd ranges from very upscale to semi-casual. I would consider the restaurant itself somewhat formal.
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Tulsa Convention Center
Tulsa, OK 74103
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Hang out at Carousel Lounge the next time you're in Tulsa and take advantage of one of their daily drink specials. ... read more...
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Few comeback stories can rival the dramatic one staged by Tulsa's historic Brady Theater. The 2,800-seat theater, ... read more...
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Hunter Park in Tulsa is a great place for the whole family to relax and have a good time. Bring along your furry friend ... read more...
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Mohawk Park, containing 2,800 acres, is the largest park in Tulsa and one of the largest in the country. The sprawling ... read more...
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The Cherry Street Farmers Market is a popular place to buy fresh local produce and goods in Tulsa's Cherry Street ... read more...
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Head to the Blue Dome Entertainment District in Tulsa for the premier dance club Electric Circus. Each Friday and ... read more...
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Boo and hiss and laugh and sing at the Spotlight Theater's presentation of "The Drunkard" and the "Olio." The Drunkard ... read more...
Email: email@example.com


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FREE SHIPPING ON THOUSANDS OF STYLES. EVERY DAY.*more info
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Women's Nike Legend Training Shirt
Get your workout on in style and comfort in the Nike Legend Women's Training Shirt (Size 1X-3X). This advanced tee is made of specialized fabric that keeps you dry, even when you work up a sweat.
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Customer Reviews


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The BRU Backup and Restore Utility features data-verified backups, scalability, configurability, and ease of use for Linux and Unix. Versions are available for Linux, FreeBSD, and most UNIX variants. It works via an X11 interface, command line interactive, or through a scripted, scheduled (CRON) mechanism.
ChemApp is a programming tool from the area of computational thermochemistry. It is a library consisting of a rich set of subroutines, based on the thermodynamic phase equilibrium calculation module of ChemSage. It permits the calculation of complex, multicomponent, multiphase chemical equilibria and their associated energy balances. ChemApp is available as object code for a wide range of platforms and as a shared library/DLL. ChemApp "light" is the free version of ChemApp, and although it is restricted in two ways compared to the regular version, it gives you almost the same functionality.
Code Medic provides access to the power of gdb with an intuitive front end. It currently supports opening multiple source windows at once, setting/clearing breakpoints while the program is running, watching variables change in the variable tree as you step through code (even with nested structs), text searching through source, and integration with Code Crusader to provide a rapid, efficient develop-debug cycle.
CodeGuide is a lean and fast IDE for Java and JavaServerPages. It features on-the-fly error checking, incremental background ("instant") compilation, powerful refactoring capabilities, and support for generic types. A visual debugger with on-the-fly class replacement (HotSwap) is also included.
CYCAS is a 2D+3D CAD package for drafting and design in high quality and for creating 3D presentations and technical illustrations easily. Some of its features include an easy-to-handle user interface, special architectural elements and functions, a WYSIWYG display, printing, plotting, import and export filters, photorealistic rendering with POV-Ray, documentation and tutorials, example drawings, and an extendable 2D/3D symbols library.
fCluster is a multi-threaded client/server redundancy application for your Linux firewall solution. fCluster is designed for the production environment with features that include: dynamic firewall synchronization, support for both ipchains and netfilter, user definable polling intervals and fail-over sequence, and email notification of a system failure. It also includes a Perl administration utility that allows you to configure both the server and the client from one machine, and view the status of the local and remote machines.
The GRASP Project has created an algorithmic-level graphical representation for software called the Control Structure Diagram (CSD). The CSD was created to improve the comprehension efficiency of Ada source code and, as a result, improve software reliability and reduce software costs. Since its creation, the CSD has been expanded and adapted to include other languages. GRASP provides the capability to generate CSD's from Ada 95, C, C++, Java, and VHDL source code in both a reverse and forward engineering mode with a level of flexibility suitable for professional application. GRASP has been integrated with the GNU family of compilers for Ada (GNAT) and C (gcc), and Sun's javac compiler for Java. Use of GRASP is not restricted to these compilers, however. This has resulted in a comprehensive graphically-based development environment for these languages. The user may view, edit, print, and compile source code as CSDs with no discernible addition to storage or computational overhead.
A generator of all major barcode formats entirely within Postscript.
An application extension programming language interpreter.


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Crafton >Restaurants >
Pizza >Portofino's Pizza & Pasta
28 W Steuben St, Pittsburgh, PA | Directions 1520540.438243 -80.068208
Mon. - Sun. 11am - 11pm
Neighborhoods: Crafton
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I have been working at Towers Watson full-time for less than a year
Pros – People are polite and you can work from home. That is about the extent of it.
Cons – This company is so archaic, it is frightening. And they believe they are "in touch" with the world as it is today. Guess again.
Advice to Senior Management – Move to the future, take a stand and set some clear direction.
No, I would not recommend this company to a friend – I'm not optimistic about the outlook for this company
I have been working at Towers Watson full-time for more than a year
I worked at Towers Watson as a contractor for more than 3 years
Towers Watson is a leading global professional services company that helps organizations improve performance through effective people, risk and financial management. With 14,000 associates around the world, we offer… — Full Overview
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Songbird Kit
Designed to motivate all types of learners in grades K-5, the Songbird Kit contains lesson plans and activities in science, literature, language arts, social studies, math and the arts.
Students learn about the natural history of Neotropical migratory songbirds, and the increasing problems these birds face in their two homes.
The Songbird Kit is available for loan to teachers in Maryland, the District of Columbia, and Virginia. The kit fosters knowledge and appreciation of migratory songbirds and an awareness of the need to conserve and protect birds and their habitats.
Contents of the Kit
The time consuming work of gathering materials is already done for you! Packaged in a durable 2' X 3' trunk, the kit includes:
- a comprehensive curriculum guide for a 2-3 week unit of study
- student research kits containing study guides, fact sheets, team badges, and task cards for cooperative learning groups
- songbird puppets
- a felt story cloth
- an array of posters, maps, books, videos, and audio tapes
Complete inventory of the kit
Teacher's Guides:
- Songbird Blues: Exploring Migratory Songbirds of the Americas
Puppets and Felt Story Cloth:
- Male Yellow-rumped Warbler or American Redstart
- Female Yellow-rumped Warbler or American Redstart & egg
- Female Brown-headed Cowbird & egg
- Nest with 4 chicks
- Male Ruby-throated Hummingbird
- Felt Story Cloth: My Changing Neighborhood
Student Research Kits:
- Twenty project task cards
- Fact Card, Range Map, and five Bird Badges for each of seven species (American Redstart, Scarlet Tanager, Indigo Bunting, Ruby-throated Hummingbird, Wood Thrush, Bobolink, Brown-headed Cowbird)
Audio Cassette Tapes:
- Voices of the Songbirds
- Songbird Symphony
- Fiesta! Mexico and Central America (music tape)
Posters and Maps:
- Birds of Two Worlds
- Disappearing Habitat, Disappearing Birds
- International Migratory Bird Day 1997 - 2002
- National Geographic Society- Bird Migration in the Americas
- National Geographic Society Map of Central America
- National Geographic Society Map of Mexico
- Partners in Flight/Compañeros de Vuelo (1996)
- Wildlife of New Jersey-Tropical Travelers
- Bird-friendly Coffee
Books and Magazines:
- Backyard Bird Watching for Kids
- Birds Over Troubled Forests
- Bridging the Americas: Migratory Birds in Costa Rica and Panama
- Eastern Birds: A Guide to Field Identification of North American Species
- Exploration Into Latin America
- Feathered Travelers
- Fiesta! Mexico and Central America (book)
- Fine Feathered Friends
- Flute's Journey
- For the Birds
- How Do Birds Find Their Way?
- The Hummingbird King
- The Hummingbird's Gift
- Kids Who Walk on Volcanoes
- Life Cycle of a Bird
- Ornithology
- Ranger Rick (May 1994)
- Save My Rainforest
- Sharing the Wonder of Birds with Kids
- Southern Mexico: Crossroads for Migratory Birds
- Birding for Kids
- Everybody Loves Birds
Reference Materials for Teachers:
- Field Checklist of Maryland and D.C. Birds
- For the Birds
- List of Local Neotropical Migratory Birds
- Smithsonian Migratory Bird Center Brochure
- Smithsonian Migratory Bird Center Checklist of Neotropical Migrants
- Smithsonian Migratory Bird Center Fact Sheets
- Suggested Resources for Teachers
- Catch the Migration Sensation classroom activity packet
- A Taste of the Tropics and Exploring Habitats
Teacher comments about the kit
"Excellent kit! Very multi-dimensional. Great for cross-curricular studies. The flannel story cloth is very effective."
"It is a wonderful kit. There is so much to choose from. We used the kit materials and worked with our Spanish teacher to study both the language and culture of Costa Rica as well as the migratory birds."
"The teachers guide contains great ideas. I loved the extensions. The kit was well equipped for all lessons. What a joy to have all the resources in this treasure box."
"The unit is well researched, well organized and thorough. Kudos to the developers."
"The kit is fabulous! The puppet shows and imaginary play acting that evolved from the lessons was well worth the effort of getting the kit to my kindergarten classroom. I love the choice of stories and tapes. I will borrow it again."
How to Borrow a Kit
Kits may be borrowed for a maximum of 4 weeks. A $25 user fee must be paid in advance, along with a $100 refundable security deposit. The kit must be picked up from and returned to the Zoo (we no longer mail kits).
To reserve a songbird kit, please complete and submit the following form. You will be contacted via email to confirm the availability of a kit for the time period you've requested.
Once dates have been confirmed, you will be asked to mail in 2 separate checks to cover the user fee and the security deposit. Please make checks payable to the Smithsonian Migratory Bird Center and mail to:
Smithsonian Migratory Bird Center
National Zoo
PO Box 37012
Washington, DC 20013-7012


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Don't miss our 7th annual American Craft Beer Fest featuring 640+ beers from 140+ brewers this May 30 & 31 in Boston, MA! Buy your tickets now!
BeerAdvocate on your phone?! True story. Try the beta now.
Schlafly Pumpkin Ale - The Schlafly Tap Room
Displayed for educational use only; do not reuse.
Ratings: 1,243 | Reviews: 432 | Show All Ratings:
4.25/5 rDev +1%
look: 4.25 | smell: 4.25 | taste: 4.25 | feel: 4.25 | overall: 4.25
Poured from a 12oz. bottle into tulip glass.
A- Pours a deep garnet with a good degree of clarity for such a dark colored beer and a pumpkin on at that. Small whitish caramel head that dissipates to a thin ring.
S- Medium level of spices of cinnamon, nutmeg, and clove. Lots of malt, similar to that of a scotch ale. Has a slight mellow gourd sort of sourness you get when smelling fresh pumpkin.
T- Similar to aroma, perfect level of spices for my tastes, a very noticeable pumpkin aspect, and a malt character that doesn't overshadow the pumpkin. Tastes the way a "from scratch" pumpkin pie ought to taste. Alcohol is not really noticeable.
M- Medium-heavy and a good lower carbonation for the style. As opposed to something like Pumking which is more effervescent.
O- I think this might be my favorite example of the style, slightly higher than Dogfish Head Punkin' and Pumking. Great balanced spices and great pumpkin flavor.
Serving type: bottle
04-03-2014 22:35:50 | More by PaulyB83
4.71/5 rDev +11.9%
look: 4.5 | smell: 4.75 | taste: 4.75 | feel: 4.5 | overall: 4.75
Great tasting beer which appears / tastes to change slightly every year! I believe this was one of the first pumpkin beers I ever tried, and to date, is still my favorite. There are lot of things going on w/ this beer that make it a great try for people of many different tastes. I would recommend this beers as a must try to start out your fall season (every year!)
Serving type: on-tap
12-13-2013 21:10:20 | More by ALC82
3.55/5 rDev -15.7%
look: 5 | smell: 4.5 | taste: 3 | feel: 4 | overall: 3.25
This parade of pumpkin beers is out of control! Every time that I think that I have opened my last one for the year, another one pops up.
From the bottle: "A Special Release, Pumpkin Ale is available for a limited time, with a new style every few months."; "Schlafly Pumpkin Ale blends the spices of the harvest with full-bodied sweetness for a beer that tastes like pumpkin pie."; "I would rather sit on a pumpkin, and have it all to myself, than be crowded on a velvet cushion - Henry David Thoreau".
My pour created two fluffy fingers of deep-tan head with great retention. Color was a deep-copper (SRM = > 22, < 27) with filament-quality brightness. Nose was very sweet and spicy and since they were going for pumpkin pie, I would say that they hit the mark! The label mentioned "cinnamon, nutmeg and clove" and I was having a tough time discerning one form another. Mouthfeel was slightly viscous, syrupy and this was one of the sweetest pumpkin beers that I can remember drinking. It seemed dangerously close to diabetic shock in a bottle. Each successive sip was unrelenting in terms of its sweetness and I was feeling kind of overwhelmed. The finish was (finally) both spicy and sweet, but if I have railed against unbalanced in terms of spices, here was unbalanced in terms of malty sweetness. Whew! Definitely NOT my cup of pumpkin, but as always, YMMV.
Serving type: bottle
12-04-2013 00:33:37 | More by woodychandler
New York
4.23/5 rDev +0.5%
look: 4.5 | smell: 4.5 | taste: 4 | feel: 4.5 | overall: 4.25
The beer comes in a light mahoghany reddish brown with ruby coming through in the light. A small half finger head.
The aroma has tons of sweet fermented pumpkin, but also brown sugar, vanilla, and the spices rolled into it. The nutmeg and cinnamon pop through. In the back, you get the brown ale toasty malt, along again with the brown sugar. A really fantastic smelling beer.
I let it warm up and it certainly opened up a bit. In the front, there's not much. And after a little bit, towards the middle, you get a pop of fresh sweet pumpkin and cinnamon and clove. The middle hits you with a bit of that toasty brown ale and brown sugar sweetness, almost like a pumpkin candy or caramel. The finish has this earthy spicy bitterness that is quite gentle.
There's lots of carbonation in this beer.
It's super drinkable at 8% and it feels like 6%. It's a well crafted beer.
Serving type: bottle
12-02-2013 01:59:45 | More by dar482
3.5/5 rDev -16.9%
look: 3.5 | smell: 3.5 | taste: 3.5 | feel: 3.5 | overall: 3.5
Pours a nice, light head. A nice, spiced aroma. Burnt umber color. Starts off sweet, clove, and carbonated. An interesting spice mix, but a bit of a lingering bitterness.
Not a very complex brew in the sense that it is very spice-forward, with a touch of sweetness in the front and bitterness in the back. Not bad by any means, but nothing really stand out.
Serving type: bottle
11-28-2013 18:39:55 | More by TheSSG
5/5 rDev +18.8%
look: 5 | smell: 5 | taste: 5 | feel: 5 | overall: 5
A-poured into snifter glass. A deep red amber color with a white head
S-wonderful aroma of pumpkin, cinnamon, and nutmeg
T-wonderful taste of the same smell with cloves
M-very rich and smooth malts maybe graham cracker
O-an absolute great pumpkin ale especially for a 12oz best taste for the money compared to other pumpkin ales
Serving type: bottle
11-28-2013 13:39:53 | More by reebtaerG
4.04/5 rDev -4%
look: 3.75 | smell: 4.5 | taste: 4 | feel: 4 | overall: 3.75
Clear brown colored beer with a small tan colored head.
Smells sweet and spicy with lots of pumpkin pie spice. Brown sugar, cinnamon, ginger and clove are the strongest scents here. Lesser scents of vanilla and caramel with some wheat crust scent. Pretty much smells like pumpkin pie.
Starts out sweet and spicy with a really strong spice flavor. Strong clove and cinnamon flavors with caramel. Pretty much it tastes like pumpkin pie.
Mouthfeel is good.
Decent pumpkin beer not too sweet with lots of Pumpkin Pie spices.
Serving type: bottle
11-27-2013 03:44:13 | More by Zorro
4.04/5 rDev -4%
look: 3.5 | smell: 3.75 | taste: 4.25 | feel: 4 | overall: 4
The beer pours a clear amber brown with little carbonation and no residual head or lacing. The nose is a rum-like mix of spices and booze, caramelized sugar, and some gourdy undertones. The taste transcends the beer's nose and appearance bringing potent pie spices to the forefront, big pumpkin sweetness, and hint of bitterness in the finish. The mouthfeel is medium, sweet bodied, slightly booze, so spiced that it's gritty, but also with an elegant gourd presence, great drinkability, and has a mildly biting, bitter finish. I do enjoy this beer and think it's refined enough to do well at the dinner table, but would likely not be my go-to beer out at a bar.
Serving type: bottle
11-24-2013 02:26:20 | More by ThePorterSorter
4.21/5 rDev 0%
look: 3.75 | smell: 4.5 | taste: 4 | feel: 4.75 | overall: 4.25
A- A murky, sort of light brownish-orange with a fizzy tan head that leaves a thick ring of bubbles around the edge of the glass. When held up to the light, there is some transparent light shining through.
S- Big aromas of clove, nutmeg, cinnamon, pumpkin bread and hints of toast. Very bold aroma, but not overwhelming.
T- The spices mentioned shine through in the flavor as well. While the nose was dominated by clove, it is mainly noticeable in the finish. Nutmeg and cinnamon come through first along with the hints of toast. Sugary pumpkin bread sweetness in the middle with clove at the end.
M- Medium-full bodied with medium carbonation. In between a full sipper and an easy drinker.
O- A very good, very solid pumpkin beer. Very nicely put together.
Serving type: bottle
11-11-2013 02:07:03 | More by stephenjmoore
New York
4.43/5 rDev +5.2%
look: 4 | smell: 4.5 | taste: 4.5 | feel: 4 | overall: 4.5
Appearance: Gorgeous amber with a 1/2 finger of white head.
Smell: Strong clove presence(similar to Good Gourd), pumpkin flesh, cinnamon and nutmeg.
Taste: It really does taste like a pumpkin pie. Amazing, and incredibly well balanced.
Mouthfeel: Medium bodied, medium carbonation.
Overall: This definitely goes in my top 5 Pumpkin beers. This kinda takes everything I like about DFH - Punkin: well balanced, Good Gourd: huge clove+sweet pumpkin, though more subdued and Pumking. Going to seek out more Schlafly now!
Serving type: bottle
11-05-2013 04:08:11 | More by PsilohsaiBiN
New Mexico
4.1/5 rDev -2.6%
look: 3.5 | smell: 4.5 | taste: 4 | feel: 4.25 | overall: 4
Small light brown to tan head settles to a super thin lacing above a thick burnt caramel colored pumpkin beer.
Light pumpkin and pumpkin pie type spices aroma with its cinnamon and nutmeg coming through nicely.
Spicy pumpkin pie taste, all it needs is a scoop of miracle whip on top of it.
Very light dryish aftertaste with a bit of the pumpkin pie tastes remaining behind with this medium bodied beer.
Pretty decent pumpkin ale, not overbearing on the pumpkin tastes but what is there is noticeable and pretty good tasting.
Serving type: bottle
11-03-2013 21:46:09 | More by LXIXME
New York
5/5 rDev +18.8%
look: 5 | smell: 5 | taste: 5 | feel: 5 | overall: 5
I am a HUGE pumpkin beer fan, gotta love that time of the year when they start popping up on the shelves in numbers. That being said, I've had a number of pumpkin beers and nothing comes even remarkably close to Schlafly's Pumpkin Ale. The best way for me to describe it is like pumpkin pie in liquid form. You would never guess the ABV based on the way it tastes, goes down very smooth. If you are a pumpkin beer fan this is a MUST have for you.
Serving type: bottle
11-01-2013 02:17:25 | More by DevinK
New York
4.23/5 rDev +0.5%
look: 4.25 | smell: 4.5 | taste: 4.25 | feel: 4 | overall: 4
Appearance - dark mahogany amber color with white head
Smell - cinnamon, nutmeg, pumkin flesh
Taste - cinnamon, nutmeg, pumpkin flesh, brown sugar
Mouthfeel - medium bodied, high carbonation, spicy and sweet upfront, dry finish
Overall - this is a solid pumpkin ale, not too heavy on the spices, very approachable
Price Point - $2.50/12 oz single
Serving type: bottle
11-01-2013 01:00:31 | More by keithmurray
4.03/5 rDev -4.3%
look: 3.5 | smell: 4.25 | taste: 4 | feel: 4 | overall: 4
12oz Bottle
Thanks to Matchew for handing me off this one! I haven't drank a pumpkin beer in a couple years. Schlafly's version pours fairly dark tarnished copper bordering on garnet. Tiny carbonation bubble rush the the surface in streams while the beige head easily grows to a finger in height and just as quickly falls to a thin ring and floating island of foam. Some soapy lacing gets left behind with each drink.
I'm not usually a fan of pumpkin beers, too artificial, but in this case both the pumpkin and spicing taste authentic and are used with constraint in mind. The nutmeg is well integrated while the clove and cinnamon are very soft. A touch of ginger brightens things up and there is plenty of gourd. A touch of caramelized grain lays a base and brown sugar adds depth without smelling overly sweet.
Flavor matches the aroma in depth but the intensity and brightness falls a little short. All the pumpkin pie spices I mentioned are there but, when compared to the smell, are slightly muddled. Besides that simple fact the other aspects remain the same. The cloyingness found in almost all other pumpkin beer is not found in Schlafly's version, thank you. The alcohol is also amazingly well hidden.
The body weighs in at medium and the mouthfeel is actually pretty slick and quick moving. The finish lingers into a welcomed dryness. There's a touch of alcohol fumes through the nose but it doesn't effect the flavor, smell, or mouthfeel of this beer in the least and adds some spiciness.
When I think of pumpkin beer I cringe. They're usually overspiced and incredibly sweet. Schlafly's Pumpkin Ale is adequately spiced, nicely pumpkinized and all around delicious. This drinks more like a beer than an overly sweet dessert. I would drink a couple of these in the fall. If you're a fan of pumpkin beers this is the best I've ever run across, give it a go. Thanks, Matt!
Serving type: bottle
10-31-2013 23:17:45 | More by joe1510
3.41/5 rDev -19%
look: 3.25 | smell: 3.25 | taste: 3.5 | feel: 3.25 | overall: 3.5
A: Mohagany/red, dark but thinly translucent
S: apple, cinnamon, clove
T: fermented apples, clove, nutmeg, slightly dry finish
M: a hint of bite, but warm and homey, a bit like a mulled cider, creamy
O: Pretty good, it makes sense why this is one of the more popular pumpkins. It might be a little too sweet for me, like ultra-fine grown-up apple juice, but drinkable, especially in smaller quantities.
Serving type: on-tap
10-22-2013 02:12:53 | More by RandomExile
4.21/5 rDev 0%
look: 3.5 | smell: 4 | taste: 4.25 | feel: 4.25 | overall: 4.5
S; Smells of pumpkin pie, cinnamon mainly. This definitely smells like a real pumpkin beer!
T: tastes like pumpkin pie! Great fall taste! Not real sweet, but yet not an overpower drive on the pumpkin either! Perfect combination on the right amount of spices!
O: one of my favorite pumpkin beers! If your looking for a pumpkin beer that tastes similar to pumpkin pie, definitely go for this beer. All time favorite pumpkin beer.
Serving type: bottle
10-21-2013 03:48:03 | More by Scarvingdozen87
3.79/5 rDev -10%
look: 4 | smell: 4 | taste: 3.75 | feel: 3.5 | overall: 3.75
From what I've heard this is supposed to be one of the better pumpkin ales out there, so I'll try not to get my expectations up too high ;)
It's certainly a beautiful autumnal beer. Crisp and clear, rich copper/amber body with a small pumpkin seed head that dissipates pretty quickly. Minimal retention and lacing.
Pumpkin spices for certain. I take the top off and start to pour and my face is inundated with autumn. The traditional pumpkin (pie) spices: nutmeg, cinnamon, creamy pumpkin, cloves, allspice, and then almost like an oktoberfest backbone of malts bringing the season to fruition.
The taste follows the cues of the nose pretty well, but almost inverted. The malts take the forefront, and as noted, they conjure thoughts of a solid oktoberfest base. Taken in a vacuum this is kind of perfect (seasonally and that), and well done, but unfortunately I'm not a big fan of oktoberfests, so it kind of distracts from the more pumpkin-y elements that I do like. The pie spices come in after this, but the distraction is still there. The spice is not as prevalent as on the nose, but it's still there. Creamy pumpkin, cloves, nutmeg, allspice, these kinds of things.
The finish is kind of bitter which stands out as it doesn't really poke through anywhere else. Overall fairly creamy, very drinkable, a good pumpkin ale. Without looking, I never would have guessed this was 8%. Alcohol hidden very very well. I'm going to bring a couple of these back to Seattle with me as my good friend and former roommate is a huge pumpkin (and pumpkin beer) fan and I think he'd really appreciate this one. Personally, I probably won't pick up another 6 pack for personal consumption, but it's definitely worth trying in season if you have any interest in the style at all.
Serving type: bottle
10-20-2013 18:59:18 | More by kemoarps
4.78/5 rDev +13.5%
look: 3.5 | smell: 4.25 | taste: 5 | feel: 5 | overall: 5
Appearance - pours an even orange/amber color. A thin off-white head on top.
Aroma - rich malt and pumpkin along with pie spices. A slight vapory component in there as well.
Taste - full malty underpinning to this pumpkin beer. Delicious pumpkin flavor, clove-forward (one of my favorite spices) without being overly sweet or overly hopped or bitter. Just a light balancing nip on the swallow and a warm abv feeling in the throat. Lengthy finish full of the gourd and lingering clove.
Mouthfeel - perhaps what really helps to nail this beer as a perennial top pick in the pumpkin beer category. Full-bodied, just shy of heavy. Crisp but not getting in the way of the taste. Smooth, but big. It's the biggest hint that the harvest season is here, the annual monstrous carbohydrate-laden meal will soon be upon us, and the malty, bigger brews of the season are nigh.
Overall - my favorite pumpkin beer for a session. The style holds a special place for me as it was the style for my first review many seasons ago. It is the only pumpkin brew I faithfully get every fall. Awesome brew, Schlafly!!!
Serving type: bottle
10-20-2013 05:02:40 | More by brewdlyhooked13
South Carolina
3.79/5 rDev -10%
look: 3.25 | smell: 3.5 | taste: 4 | feel: 3.25 | overall: 4
12 oz bottle served in a snifter.
Pours clear, dark amber color with a modest tan head. A small amount of sediment lurking at the bottom of the bottle was added to the pour.
Despite plenty of pie spices, the pumpkin shines thru as well. More spicy in the flavor and feel than in the nose, particular the cinnamon component. Perhaps due to a richer malt base, even with rather bold spicing this pumpkin is not over-spiced. Those not liking cinnamon probably will disagree; this has enough cinnamon to, I think, add a slight burn to the feel. Still, very nice mix of flavors.
O: very similar to the Whole Hog Pumpkin I had a couple of days ago in both profile and overall quality. These are among the best pumpkins I've tried, and clearly the best of the 5 I've had over the past 3 days. More clove in the Schlafly; slight preference for the Whole Hog.
Serving type: bottle
10-17-2013 23:42:01 | More by chinchill
4.11/5 rDev -2.4%
look: 4 | smell: 3.75 | taste: 4.25 | feel: 4 | overall: 4.25
Bottled with love on 8/14/13.
Aroma is more spice than pumpkin. Sometimes heavy on nutmeg and other times cinnamon. Some roasted pumpkin in the background.
Darker orange pushing to browns in the amber. Tan head that is smallish, but hangs around pretty well.
Roasted pumpkin really shows in the taste. Still containing ample spice and a firm shot of alcohol adds a bite (and a quick shot of warmth to the wheelhouse). Not much more complicated than that. Just all those flavors rolling around for an enjoyable experience.
Moderate to a little thinner on the feel. Carbonated well but not to excess.
This is a nice seasonal ale. Going with the current trend of higher abv, which seems to work well.
Serving type: bottle
10-13-2013 17:40:35 | More by garymuchow
4.44/5 rDev +5.5%
look: 4.25 | smell: 4.25 | taste: 4.5 | feel: 4.5 | overall: 4.5
Poured from the bottle into a shaker pint. Ok.. so you are not a fan of pumpkin ale, but can be objective... but hey we are a Schlafly fan so I gotta try this.
Quite dark for a pumpkin ale, deep red orange almost bronze and very clear. Three to four finger tall head, slightly orange with a yellowish tan like tinge to it, and a creamy consistency. Some retention but does manage to fall somewhat quickly.
Nose is classic spicing pumpkin, but more of a spritzy zesty angle. Very hot cloves, and mild subdued sweetness. Slightly vegetative, but there's a hint possibly of some caramel hiding here which makes for some unique qualities.
Palate is quite interesting. Sweetness is very mellowed down, with lots of bready qualities and nutmeg. Doughy and dense with a very nice thick but not distracting syrupy body. Spicy cinnamon finish and tasting caramel deep malts. Playful carbonation that tickles the palate. Kind of like a playful mellow pumpkin winter warmer.
Considering I am not a fan of this style, this hits the right notes without being overly sweet like most pumpkin ales. Another hit in the Schlafly collection.
Serving type: bottle
10-10-2013 00:14:35 | More by smakawhat
District of Columbia
3.44/5 rDev -18.3%
look: 3.25 | smell: 3.5 | taste: 3.5 | feel: 3.5 | overall: 3.25
Pours auburn with no head retention. Midway through drink, it looked more like a rise wine or bourbon. The smell has berry and plum notes along with the pumpkin spice notes.
My first sips were enjoyable, even though the fruitiness noted in the nose was just as present in the taste. The fall spiciness was nice, and perhaps the only off-putting thing was the obviousness of the alcohol.
As I sipped it more, it seemed to lose its effervescence and tasted more like it looked, like a fortified wine. Because it's "beeriness" faded, I rated it down. My initial tastes had me rating it about .5 higher. Maybe I had a glass from a bad keg.
I will have to mark this for a re-try.
Serving type: on-tap
10-09-2013 22:07:07 | More by cjgiant
4.39/5 rDev +4.3%
look: 4.25 | smell: 4.5 | taste: 4.5 | feel: 4 | overall: 4.25
12oz bottle, bottle is dated 8/14/2013 (I assume this is bottling date. If this is the enjoy by date, the whole pumpkin-beers-in-the-summer angst just got even more ridiculous). Poured into an unlabeled snifter today, 10/7/2013.
Pours a dark brown-amber body, somewhat opaque and when illuminated, it becomes more of a dark burnt orange colour. Comes with a nice white head, around 1cm that looks substantial and slowly dissipates into a thick film and reasonably sized collar. Lacing comes up as the beer disappears, but slowly drops back into the collar. We got a great looking pumpkin beer here.
Smells like friggin' pumpkin pie mix. Tons of pumpkin spices balanced out by a nice bready malt backbone that reminds me of sweet potatoes. There's definitely nutmeg mixed with some cinnamon. Maybe some molasses or brown sugar-like sweetness on top of the bready malts. Phew!
Tastes just like pumpkin pie as well. Fall spices being some mixture of cloves, nutmeg and cinnamon are a bit less dominant throughout than in the nose, whereas the sweet potato-like bready malts shine a bit more. The spices do come back with a vengeance on the backend, but there is a mild bit of earthy bitterness that balances it out. Delicious.
Medium bodied, smooth, well-carbonated. Slight alcohol burn. Dessert-like beer that is sticky on the lips and palate.
Lip-smackingly good. One of the few pumpkin beers I've really enjoyed this year. This is up there with Good Gourd in terms of how much this smells and tastes like pumpkin pie. The smell is really something on this one. Highly recommend if you are interested in pumpkin beers and haven't tried this one yet.
Serving type: bottle
10-08-2013 03:22:15 | More by Stevedore
4/5 rDev -5%
look: 4 | smell: 4 | taste: 4 | feel: 4 | overall: 4
A-orange amber color with a decent cream colored head and little lacing
S-toasted malt, pumpkin, cinnamon, hint of brown sugar
T-pumpkin, cinnamon, nutmeg, toasted malt, mild bitterness in the finish
F-medium body with moderate carbonation, crisp
O-solid pumpkin beer, but lacks depth of flavor and complexity of some others
Serving type: bottle
10-06-2013 19:28:51 | More by MDDMD
3.98/5 rDev -5.5%
look: 4 | smell: 4 | taste: 4 | feel: 4.25 | overall: 3.75
The best pumpkin beer I have had....Hands Down. I Will admit I have only had a few different pumpkin beers some good some not so good. But I recommend this pumpkin brew for anyone who has not tried one as well as Veteran pumpkin boozers. Pick this up n stash it for later in the year.
Serving type: bottle
10-06-2013 19:22:46 | More by Mike4TN
Schlafly Pumpkin Ale from The Schlafly Tap Room
94 out of 100 based on 1,243 ratings.


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- The Jeff Probst Show | Parenting | Thu, May 9, 2013 4:45 PM EDT | Comments
It takes a very special person to start a charity that benefits those in need, and as you'll see in this clip from "The Jeff Probst Show," Alanna Wall is one of those very special people. She's also just 12 years old! Alanna was only 10 when she started Polished Girlz, an organization that bring nail polish parties to girls that are hospitalized or have special needs.
Alanna's love of sharing nail art also comes with a message about how important it is to wash your hands. Check out the video to hear about all the great work that Polished Girlz does!
She's a 17-Year-Old CEO!
Jeff Gives An Aspiring Talk Show Host The Chance of a Lifetime!
How to Save Money for College
Alanna Wall on The Jeff Probst Show
...Read More »
- The Jeff Probst Show | Parenting | Thu, May 9, 2013 4:34 PM EDT | Comments
Aaron Collins was only 30 years old when he died unexpectedly. A few days later, his brother Seth was going through his things when he found, on his computer, a will. One of the instructions was quite explicit - Aaron wanted his family to leave a $500 tip to an unsuspecting waiter or waitress.
Seth and his mother, Tina, fulfilled Aaron's wish a few days later, and they shared a video of it on YouTube for some loved ones. They weren't expecting the video to go viral, but it did - and soon, a movement was born!
In this clip from "The Jeff Probst Show," Seth and Tina explain how their simple act of kindness on Aaron's behalf spread like wildfire, and inspired people to pony up tens of thousands of dollars so they can keep the $500 tips coming! If you'd like to learn more about how to get involved, visit AaronCollins.org.
A Powerful Organ Donation Story
She Chose an Insane Asylum To Save Her Baby's Life
The Devastating Effects When One
- The Jeff Probst Show | Love + Sex | Mon, Apr 29, 2013 8:14 PM EDT | Comments
The film version of the steamy hit novel "50 Shades of Grey" is already one of the most anticipated movies around - and it hasn't even begun filming yet! But that hasn't stopped rumors from spreading about which actor will be cast to play the leading role of Christian Grey, the handsome millionaire with a secretive love life. One of the names that's making the rounds on the rumor mill is Colin Egglesfield, from "The Client List," "Rizzoli & Isles," and "All My Children."
Related Content: Colin Egglesfield - The Full Interview
In this clip from "The Jeff Probst Show," Colin addresses those rumors head on - including what skills he's picked up on the set of "The Client List" that would come in handy to play Christian Grey!
Jeff Interviews "Rules of Engagement" Star Patrick Warburton
The Man Being Called "The Next Dr. Seuss"
Breaking Barriers in a Male-Dominated Sport
The Jeff Probst Show
...Read More »
- The Jeff Probst Show | Pets | Thu, Apr 25, 2013 8:32 PM EDT | Comments
Lt. Chet Frith came back from multiple tours in Iraq and started suffering from an intense case of post-traumatic stress disorder. His lifeline? A service dog named Gunner. In this clip from "The Jeff Probst Show," Chet explains what he means when he says that Gunner, who is trained to keep an eye on Chet and his surroundings, saved his life. It's a touching story of what man's best friend can do!
The Dog That Can Ride a Bike
Celebrity Hairstylist Ken Paves Shows Off His Dogs' Wigs
The Amazing 6 Year Old Boy That's Raised $150,000 to Help His Best Friend
The Jeff Probst Show
...Read More »
- The Jeff Probst Show | Healthy Living | Wed, Apr 10, 2013 8:41 PM EDT | Comments
Caitlin Doughty studied medieval history in college, but found, after graduating, that it's not a field that lends itself to many job opportunities. So Caitlin, who has always been interested by death, decided to take a different path, and now, Caitlin is a mortician.
In this clip from "The Jeff Probst Show," Caitlin shares with Jeff the ins and outs of her career, including why she wears the clothes she wears, the outrageous questions people ask her parties, and how society has changed over the past 100 years when it comes to dealing with death.
The Hilarious Melissa Peterman's Interview with Jeff
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The Jeff Probst Show
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text:
Back To School Bash Signals Stretch Run For HPT.Com Speedway Racers
Topeka, KS - This Saturday night at HPT.Com Speedway is celebrating a 'Back to School Bash.' There are several ways you can look at this evening. Parents will love this night because they are about to get a well-deserved break. Kids aren't going to love it so much because they know that summer is almost over. Racers will know that there are just a handful of races left to make up points or extend their points lead.
No matter how you look at it, HPT.Com Speedway will be hosting another fun promotion that will be highlighted by the best dirt racing in the midwest.
Heartland Park Topeka officials decided to make this Saturday night, a beneficial one. They are going to be collecting school supplies items to give to the local youth returning to school. Fans will have the opportunity to donate school supplies at the ticket window. If fans donate items they will receive $2.00 off the regular adult admission.
There will also be a ton of fun and games centered around the back to school theme. It should be a great time for all who attend.
On the race track it's time for race #17 of the BriggsAuto.Com Super Saturday Showdown Series. So far in 2011 the racers have lived up to all of the hype.
Darron Fuqua won the feature in the Washburn Tech Modified division last Satruday night. It was an emotional win after his father passed away on the previous Sunday.
This season Fuqua has rolled to 10 victories, as a matter of fact, he has not lost a race since June 25! This has been one of the greatest single seasons ever by an HPT Modified driver and there are still several races left.
In the Super 8 at Forbes Landing Factory Stocks, Dave Samuels rolled to win #7 on the season. Even though he has the most wins in the class this season, he is still chasing the points leader Steve Herrick for that all-important track championship.
One of the tightest points races might be developing in the White Line CDL Training B Mods. Mike Higley stormed to his 5th win of the season last Saturday night, but he is also gaining ground on the points leader, Dalton Kirk.
What seemed to be a big lead for Kirk has evaporated over the last few weeks and now these two are primed for a solid duel down to the wire.
A driver that seems to be having no problems whatsoever this season is Zach Henery. Henery is on a whirlwind this season. Last Saturday night he collected his 11th win of the season and he has a comfortable points lead heading down the stretch. Like Fuqua in the Modifiieds, Henery is having one of the best seasons of any driver in any division.
All season long the competitors of HPT.Com Speedway have been putting it on the line and the fans have come to enjoy the action on the speedway. Make plans this Saturday night to come out and enjoy the last weekend before school starts and the best dirt track racing in the midwest!
Saturday night the spectator gates open up at 6 p.m., hot laps will start at 6:45 p.m. and the racing goes green at 7:30 p.m.
Adult ticket prices are $10 and children 12 and under are just $5.00.
Don't forget to bring your school supplies to donate and receive $2.00 off an adult general admission ticket.


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In the near future, the Food and Drug Administration will launch an aggressive inspection of foreign factories that make drugs for consumption in the U.S. Forty percent of the nation's pharmaceutical supply is manufactured overseas, where regulation historically has been light and problems have been growing.
The coming inspections owe much to the 2008 heparin scandal, in which Chinese suppliers knowingly adulterated ingredients in the blood-thinning drug. They also reflect the tireless efforts of Heather Bresch, a young former secretary from West Virginia who became CEO of generic drug-maker Mylan MYL +0.14% Mylan Inc. U.S.: Nasdaq $50.35 +0.07 +0.14% April 24, 2014 4:00 pm Volume (Delayed 15m) : 6.21M AFTER HOURS $50.35 0.00 0.00% April 24, 2014 5:31 pm Volume (Delayed 15m): 644,466 P/E Ratio 30.70 Market Cap $18.70 Billion Dividend Yield N/A Rev. per Employee $348,482 04/17/14 Teva Can Release Generic Celeb... 04/07/14 Mallinckrodt to Buy Questcor P... 04/04/14 HEARD ON THE STREET: Mylan Mis... More quote details and news » (ticker: MYL) in January 2012. Due to her determination, fearlessness, and prodigious work ethic, Bresch accomplished what even the president of the United States has a tough time doing: getting a law passed.
The so-called Generic Drug User Fee Act of 2012 was passed last year as part of a legislative overhaul of the FDA. It will level the playing field for all drug makers, enhance the attraction of manufacturing in the U.S., and raise costs for overseas factories that want to sell pharmaceutical products here, including many Mylan rivals. "Keeping a factory compliant with good manufacturing practices costs 25% more," says Bresch, who notes that Pittsburgh-based Mylan "has been running this way all along."
A workhorse in platform soles, Bresch is known for making quick decisions. Evan Kafka for Barron's
A reputation for ethics and excellence will stand Mylan in good stead as it expands around the world, where aging populations need affordable drugs. "That adds up to a double-digit growth rate for a public company over the next five years, which is pretty attractive," Bresch says.
Then again, Mylan hasn't been coasting. Earnings rose more than 25% last year, to $2.59 a share, and the shares are up 38%, to $29.61, since Bresch took charge. The company has said it intends to earn $6 a share by 2018.
THE CEO OF MYLAN has honey-colored hair and cuts a trim figure in an eyelet-edged dress. At 43, she is one of the youngest CEOs of a large American corporation—in this case, one with a $12 billion market capitalization and more than $7 billion in annual sales. Her manner is unguarded and she speaks with a disarming twang, a legacy, perhaps, of her upbringing in West Virginia, where members of her large Italian-American family once made their living mining coal and running small businesses.
Bresch is as persuasive as a politician, a career that also runs in the family. Her father, Joe Manchin, is the former governor of West Virginia, and now the state's junior senator in Washington, D.C. Years ago, as a state senator, he ran into Mylan's co-founder, Milan Puskar, at a West Virginia University basketball game, and told him Bresch was job-hunting. Puskar gave her a job, in the basement of Mylan's Morgantown, W.Va., factory, typing labels for the company's quality-assurance program.
She didn't stay in the basement for long. Bresch soon was promoted to the business-development office at Mylan. By 2002, she was director of government relations, a key role at a company in a heavily regulated industry. She then moved on to spokeswoman, head of strategic development, and chief operating officer, and began pushing for acquisitions that would triple Mylan's size.
GENERIC-DRUG MANUFACTURERS wage hand-to-hand combat over each patent expiration. The industry succeeded by incentivizing distributors, but bitter competition put a strain on profit margins. Generics already accounted for two-thirds of U.S. drug sales in the mid-2000s, and competition was coming from Indian manufacturers such as Ranbaxy Laboratories (now a unit of Japan's Daiichi Sankyo 4568.to +0.64% Daiichi Sankyo Co. Ltd. Japan: Tokyo ¥1741 +11 +0.64% April 25, 2014 3:00 pm Volume : 1.89M P/E Ratio 13.61 Market Cap ¥1228.72 Billion Dividend Yield 3.45% Rev. per Employee ¥32,867,500 04/25/14 NTT Docomo to exit India with ... 04/25/14 (Japanese Companies Get) Lesso... 04/24/14 Sun's Ranbaxy Dilemma: What to... More quote details and news » (4568.Japan), and Dr. Reddy's Laboratories RDY +0.72% Dr. Reddy's Laboratories Ltd. ADS U.S.: NYSE $43.42 +0.31 +0.72% April 24, 2014 4:02 pm Volume (Delayed 15m) : 377,695 AFTER HOURS $43.29 -0.13 -0.30% April 24, 2014 4:43 pm Volume (Delayed 15m): 941 P/E Ratio 19.47 Market Cap $7.14 Billion Dividend Yield 0.57% Rev. per Employee $133,917 More quote details and news » (RDY). Mylan needed to get bigger.
In 2006, Mylan bought India's Matrix Laboratories, a maker of active ingredients and HIV treatments. The next year, Germany's Merck mrk.xe -0.29% Merck KGaA Germany: Xetra €119.30 -0.35 -0.29% April 25, 2014 9:31 am Volume : 10,413 P/E Ratio 21.61 Market Cap €25.98 Billion Dividend Yield 1.59% Rev. per Employee €290,798 04/23/14 With Novartis-Glaxo Deal, Furt... 03/06/14 Merck Profit Lifted by Cost Sa... 02/26/14 Lanxess Warns of 2013 Loss, Cu... More quote details and news » (MRK.Germany) decided to sell its generics division. All the big pharma companies kicked the tires until, out of nowhere, Mylan bid $6.7 billion in a deal that would make it the world's No. 3 generics company, after Teva Pharmaceutical Industries teva -1.64% Teva Pharmaceutical Industries Ltd. ADS U.S.: NYSE $49.84 -0.83 -1.64% April 24, 2014 4:03 pm Volume (Delayed 15m) : 3.81M AFTER HOURS $49.65 -0.19 -0.38% April 24, 2014 6:55 pm Volume (Delayed 15m): 1,242 P/E Ratio 32.20 Market Cap $48.81 Billion Dividend Yield 2.77% Rev. per Employee $453,222 04/24/14 Actavis Settles Celebrex Case ... 04/18/14 Chief Justice Roberts Refuses ... 04/18/14 Chief Justice Refuses to Block... More quote details and news » (TEVA) and Sandoz, which is owned by Novartis NVS -1.83% Novartis AG ADS U.S.: NYSE $84.59 -1.58 -1.83% April 24, 2014 4:03 pm Volume (Delayed 15m) : 2.46M AFTER HOURS $84.61 +0.02 +0.02% April 24, 2014 5:16 pm Volume (Delayed 15m): 93,020 P/E Ratio 22.32 Market Cap $233.95 Billion Dividend Yield 3.26% Rev. per Employee $426,538 03/31/14 Novartis Boosted by Heart Drug... More quote details and news » (NVS). But Mylan was paying more than its own market value for a company twice as large, and its shares promptly collapsed.
The deal swelled Mylan's debt load to $8 billion, but also afforded Bresch an opportunity to showcase her business acumen. All of Merck's branded and generic products were intertwined, and disentangling them would be difficult. Mylan's then-CEO, Robert Coury, hired Boston Consulting Group to advise on the project, and put Bresch in charge of the integration. She introduced a system to track every aspect of the process, utilizing red, yellow, and green lights to denote progress.
"We broke the record," says Coury. "She shone and delivered, saving the company tons of money. At first we told Wall Street we'd deliver $150 million of [cost-saving] synergies. We stopped counting at $500 million. We couldn't have hit it had it not been for [Bresch's] complex and disciplined model."
Bresch is known for making rapid decisions. "She works 100 times harder than the person next to her," Coury says.
Not everything went smoothly in these years. In 2008, following a newspaper investigation, Bresch's alma mater, West Virginia University, found that she hadn't fulfilled all academic requirements for an executive MBA degree listed on her resume. She claimed at the time that the university had allowed her to substitute fieldwork for academic experience. The school subsequently granted her the degree after changing various "incompletes" to grades, but the president and several other administrators were forced out amid charges of caving to political pressure. Later, West Virginia revoked the degree, and Bresch didn't challenge it. "It's a no-win for me to comment about this," she says.
Despite the contretemps, Bresch was named president of Mylan in 2009, and became CEO in 2012 when Coury stepped aside. Just 52, he has stayed on as executive chairman, and is heavily involved in corporate strategy.
IN THE MID-2000S, Bresch began to tackle the issue of regulatory oversight, which would make her famous. "I wasn't aware that there were two different standards for products sold in the U.S.," she says. "If you were a manufacturer in the U.S., you were subjected to a GMP [good manufacturing practice] inspection once every two years to get a clean bill of health."
But the law was silent on manufacturing elsewhere. "It took 10, 12, 13 years, or perhaps never, for a [non-U.S.] facility to be inspected that was selling product in the U.S.," she says. Bresch realized that manufacturers were exposing themselves to potentially huge liabilities.
The heparin scandal showed how complex the global supply chain had become. Yet, the FDA had no current database of foreign factories, and when the financial crisis hit, it had insufficient funding. Regulators began banging the drum for generic-drug manufacturers to pay user fees for the FDA's services, just as branded drug makers did. And Bresch began agitating for a quid pro quo for the generics industry. She thought the industry ought to agree to user fees, but demand that the funds be used to boost the agency's authority overseas.
Although the next vote to reauthorize prescription-drug fees was scheduled for late 2012, some two years hence, Bresch felt the need to act quickly. "My leadership style is that nothing gets better with age," she says.
First, she commissioned a white paper detailing that, even as foreign facilities grew by 185% from 2001 to 2008, the FDA inspected just 8% a year. In September 2010 she attended an FDA open forum on user fees, and asked the crowd, "Do you believe every product you give your children should be held to the same standard if it wasn't made in the United States?"
A few months later, she spoke at a Pew Charitable Trusts conference about the heparin scandal. "That was the catalyst for action on Capitol Hill," says Allan Coukell, a pharmacist who also directed Pew's medical-safety division.
Bresch sent her chief of staff, Marcie McClintic Coates, to negotiate with the FDA about fees, giving her this advice: "The hardest-working person wins. Period. You need to outwork every FDA lawyer, every pharma lawyer, bury them with your work ethic, because if you know what you are doing and speak intelligently, you win."
Coates figures she spent 140 hours just at the negotiating table. Key to her victory were admissions like that of FDA Commissioner Peggy Hamburg that the agency hadn't inspected some sites in 13 years. The FDA declined to comment.
BRESCH MADE HUNDREDS of visits to Capitol Hill, wheedling senators to support the Generic Drug User Fee Act on patriotic grounds. "You're letting all my competitors, paying half the tax rate of Mylan, come into our country without the infrastructure or spending…to make sure there's quality medicine," she told them.
She worked both sides of the aisle, paying countless visits to Rep. John Dingell, the powerful Democrat who headed the Energy and Commerce Committee. "She is one of the smartest people I've ever dealt with," Dingell says. "She did a super, honest, and honorable job."
Adds Sen. Manchin, "All these senators were flabbergasted when they found out she was my daughter. Of course, John Dingell wanted to adopt her."
On July 9, 2012, President Obama signed the bill into law. The New York Times singled out Bresch for credit, and Esquire magazine dubbed her one of its "Americans of the Year."
"I think I was able to pull every ounce of the fabric of who I am and what's made me, from growing up in a political family to policy being in my blood, to my curiosity about wanting to figure out a problem," Bresch says.
Now it's on to new challenges, and back to work at Mylan. The company is investing heavily in research and development, and has numerous drug launches planned. Business is recovering in Europe and booming in Asia, where Mylan has launched a new business with Pfizer PFE -0.68% Pfizer Inc. U.S.: NYSE $30.71 -0.21 -0.68% April 24, 2014 4:00 pm Volume (Delayed 15m) : 24.47M AFTER HOURS $30.71 0.00 0.00% April 24, 2014 6:58 pm Volume (Delayed 15m): 491,801 P/E Ratio 18.01 Market Cap $197.36 Billion Dividend Yield 3.39% Rev. per Employee $663,887 04/24/14 AstraZeneca Earnings Dented by... 04/24/14 Heard on the Street: AstraZene... 04/24/14 Actavis Settles Celebrex Case ... More quote details and news » (PFE) in Japan. Just last week, it agreed to buy an Indian company that specializes in generic versions of injectable drugs.
Bresch, meanwhile, is crusading for wider distribution of EpiPens, which carry an injectable antidote to allergic reactions. She maintains they should be as widely available as cardiac defibrillators.
"I grew up in an era when generics were considered inferior," she says. "People thought they were made in a bathtub."
But not any more, due in part to Mylan's success and Bresch's quality-control crusade.
E-mail: firstname.lastname@example.com


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Recommended Just For You
Here's What Our Customers Are Saying
Perfect magnet
Burgundy Champagne Save the Date Magnets Easy to personalize and used our wedding colors. Arrived quickly. Quality of picture and print was excellent, as was the size. Turned out perfect, better than I hoped. I highly recommend this product.


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THE VAMPIRE DIARIES–"The Rager"–Image: TVD403A_0140b –Pictured: Ian Somerhalder as Damon–Photo: Annette Brown/ The CW–©2012 The CW Network. All Rights Reserved.
October 7, 2012
If you're anything like us, you're constantly bugging your TV-watching buddies to tell you "what happens next". But let's face it, they probably don't know either.
Here at Spoilers Guide, we're all about blogging spoilers and know-how for the most popular series on TV. We aim to familiarize fans with upcoming story arcs and exclusive info before it even hits your small screen.


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News from WTOP
News from the AP
Mike Causey
Shows & Panels
Shows & Panels
Shows & Panels
Shows & Panels
- The 2014 Big Picture on Cyber Security
- AFCEA Answers
- Ask the CIO
- CDWG/NetApp
- Connected Government
- Consolidating Mission-critical Systems
- Constituent Servicing
- The Data Privacy Imperative: Safeguarding Sensitive Data
- Eliminating the Pitfalls: Steps to Virtualization in Government
- Federal Executive Forum
- Federal Tech Talk
- Government Cloud Brokerage: Who, What, When, Where, Why?
- Government Mobility
- The Intersection: Where Technology Meets Transformation
- Maximizing ROI Through Data Center Consolidation
- Mobile Device Management
- The Modern Federal Threat Landscape
- Moving to the Cloud. What's the best approach for me
- Navigating Tough Choices in Government Cloud Computing
- Satellite Communications: Acquiring SATCOM in Tight Times
- Transformative Technology: Desktop Virtualization in Government
- Understanding the Intersection of Customer Service and Security in the Cloud
Shows & Panels
On February 17, 2009, President Barack Obama signed The American Recovery and Reinvestment Act, or Recovery Act, into law. Federal News Radio follows how agencies have enacted the law and how the government is tracking spending through Recovery.gov.
Energy Efficiency Retrofits
Monday - 4/26/2010, 11:21am EDT
Under a Department of Energy initiative, communities, governments, private sector companies and non-profits will work together on programs for concentrated retrofits of neighborhoods and towns - and eventually entire states.
Meeting one of the Energy Department's missions, the models are expected to save households and businesses about a $100 million annually in utility bills, while leveraging private sector resources, to create what could be as many as 30,000 new jobs over the next three years.


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Taliaferro Earns Daktronics All-Region First Team Honors, Lee and Penston Named to Second Team
DAHLONEGA, Ga. – The North Georgia College & State University women's soccer team has enjoyed a great run of success the past four seasons that has seen the program achieve a record of 55-18-6. Three of the players who have helped the program achieve that record, Cicely Taliaferro, Taylor Lee and Kelly Penston, were recognized Monday as members of the 2012 Daktronics All-Southeast Region teams.
Taliaferro was named a first team selection and is up for consideration for All-Amerca honors while Lee and Penston were named to the second team.
In total, 14 players from the Peach Belt Conference were named as either first or second team nominations with Armstrong Atlantic State University's Morgan Mitchell earning Southeast Region Player of the Year honors. Columbus State University had the most players named to the two squads with six – four first team and two second team selections.
Taliaferro is a sophomore midfielder who started all 22 games for the Saints this season. She finished the year tied for third on the team with nine goals that, when coupled with four assists, gave her 22 points which was good enough for fourth on the team.
An All-Peach Belt Conference Second Team selection this season, Taliaferro scored the game-winner in the Saints' season finale against USC Aiken. For the season, she took 41 shots with 27 being on goal.
Lee, a graduating senior from McDonough, Ga., is a two-time Peach Belt Conference All-Tournament selection who led the team this season with 10 assists – good enough for second-most assists recorded in a single season in school history. It is the second season in a row that she has led the team in the category and her 17 career assists leaves her second all-time in school history for the category.
Earlier this month, Lee was named to the 2012 Capital One Academic All-District 3 team and is also a two-time PBC All-Academic selection.
Penston joins former women's soccer great Casey Smith as the only two players in North Georgia's NCAA era to earn multiple all-region plaudits as she was also named to the 2011 National Soccer Coaches Association of America (NSCAA) All-Southeast Region Second Team. Smith was a three-time all-region selection.
A redshirt junior from Suwanne, Ga., Penston is a three-time All-Peach Belt Conference selection, including being named to the first team in 2012. She was also named to the PBC's Preseason All-Conference team prior to this season.
In her four years with the program, Penston has ascended to second all-time in school history with 58 points and 24 goals. She is just 12 points shy of first place and needs just six goals to tie first place in that category. Her 12 goals this season is also tied for second all-time while her 28 points is the third-best point total in a single season.
2012 Daktronics NCAA Division II All-Southeast Region Team
First Team
Pos Name School Yr Hometown
GK Mary Mancin Columbus State Sr. Gainesville, Ga.
F Morgan Mitchell Armstrong Sr. Lilburn, Ga.
F Jade Montgomery Wingate So. Monroe, N.C.
F Amalia Arvidsson UNC Pembroke So. Boras, Sweden
F Leah Mullins Lenoir-Rhyne Fr. Kissimmee, Fla.
MF Stephanie Lowery Columbus State Sr. Sandy, Utah
MF Nadima Skeff Armstrong Sr. Brasilia, Brazil
MF Gabrielle Brodie Newberry So. Rolleston, New Zealand
MF Cicely Taliaferro North Georgia So. Marietta, Ga.
D Emily Cattanach Armstrong Sr. Ft. Myers, Fla.
D Kansas Bayly Columbus State Jr. Lilburn, Ga.
D Kayla Brown Columbus State Sr. Lawrenceville, Ga.
D Brianna Belsky Lenoir-Rhyne Fr. Egg Harbour Township, N.J.
Second Team
Pos Name School Yr Hometown
GK Caitlyn Scruggs Lenoir-Rhyne Sr. Torrance, Calif.
F Tramicka James Tusculum Sr. Wilson, Fla.
F Kelly Penston North Georgia Jr. Suwanee, Ga.
F Natalia Valentine Clayton State Sr. Bocksburg, South Africa
F Gabriela Reid Limestone So. Birmingham, England
MF Hanna Keibel Lenoir-Rhyne So. Parker, Colo.
MF Carley Griffin Lenoir-Rhyne Sr. Fresno, Calif.
MF Kaitlyn Kerrigan Lees-McRae Jr. Lakewood Ranch, Fla.
MF Catherine Lovin Columbus State Sr. Griffin, Ga.
D Taylor Lee North Georgia Sr. McDonough, Ga.
D Kelly Moldenhauer Wingate Sr. Mint Hill, N.C.
D Shelby Rolling Columbus State Fr. Stayner, Ontario
D Amber Madriaga Lenoir-Rhyne Fr. Wailuku, Hawai'i
Southeast Region Player of the Year: Armstrong senior forward Morgan Mitchell (Lilburn, Ga.)


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Tempilaq Temperature Indicator 500 Degree 2 oz
Product #: 411107 Tempilaq #: 88075890 UPC #: 608050122026
Product Information
This non-flammable, quick-drying fluid dries to a dull matte finish then liquefies when the rated temperature is reached. For use on polished metal, glass, plastics or rubber.
Technical Information
Quick-drying fluid dries to a dull film
When rated temperature is reached, film will liquefy, dull opaque appearance changes to bright and clear
Reliably accurate to plus or minus 1 percent
Application: Polished Metal, Glass, Plastics, Rubber Fabrics, Electronic Components, Dielectric Heat Sealing, Post Forming Plastic Laminate, and Annealing Polished Metal Surfaces.
Technical Information
Know someone who may like this? Email this Page to a Friend
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The statements and opinions expressed within Customer Reviews reflect each author's personal perspective and do not imply endorsement by MidwayUSA, its Employees or any other organization. Customers should in no way infer that MidwayUSA has validated review information as safe, accurate or appropriate.
NOTE: Prices, specifications and availability are subject to change without notice.
We reserve the right to correct typographic, photographic and/or descriptive errors.
We reserve the right to correct typographic, photographic and/or descriptive errors.


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Our Mission
The mission of the Office of Human Resources at XU is to support the Xavier community in the education and formation of students, to cultivate an organizational culture that welcomes and inspires excellence, and to collaboratively address employee issues to maximize individual and organizational performance, health and well-being while preserving our Jesuit character as the premier university in the region.
Interested in working at Xavier University?
Take a look at the current openings at an institution rated in the top 10 by U.S. News & World Report for over 10 consecutive years.


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Census of Ireland 1901/1911
The household returns and ancillary records for the censuses of Ireland of 1901 and 1911, which are in the custody of the National Archives of Ireland, represent an extremely valuable part of the Irish national heritage. Read more about their digitisation.
All thirty-two counties for 1901 and 1911, searchable by all information categories, are now available on this site. Corrections and improvements will be ongoing, and we are very grateful to all users who have submitted corrections to us. A small amount of material is missing from the site, and will be placed online as soon as possible.
See User Corrections for information about data updates to the site.
Other Places to Look
What was early 20th century Ireland like?
See our illustrated account of the country, including material for Cork, Galway and Waterford:
- Read about transport, and look at a tram timetable for 1911
- Read about literature and see Oliver St. John Gogartys census return, where he momentarily forgot he was married
- Read about Belfasts shipbuilders, and see the Titanic under construction
- See photograph of an eviction in Woodford, Co. Galway
- See census return for the Marquis of Waterford, Curraghmore
- See photograph of women workers in tobacco factory in Cork city
- Read about sport and see a photo of the All-Ireland winning Kerry football team of 1903
Further contextual and illustrative material will appear on the site over the coming months, subject to budgetary constraints.


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Antiqued Hen
Egg Cup
Antiqued Hen captures the rustic charm of country farmhouse style and brings it to your tabletop. A single embossed hen adorns the top of this dinnerware, which is bordered by a subtle vine design that perfectly complements the scalloped edges. Constructed of earthenware. Microwave and dishwasher safe. This whimsical hen egg holder makes breakfast a delight for both grown-ups and kids! Perfect for serving soft-boiled eggs, or display colorful painted or carved eggs as a decorative accent. Egg cup measures 3-1/2 inch high.


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If there is a thread on this, I could not locate it.
Geberit has a great video for installation of their in-wall carrier/tank. Is installation of TOTO's in-wall tank/carrier similar enough that the Geberit video can serve as a general guide? I know the TOTO has a written installation guide, but just for planning, the Geberit video is really helpful.


text: Restless leg syndrome affects millions of people, and seems like a silly and strange diagnosis – almost like a make-believe or phony disorder just to sell more pills or something. If you peruse the internet you will quickly find that the disorder isn't understood at all. The cause is generally unknown, and any theories about what causes it or will make it go away are fine examples of wild speculation. I am very excited to report what I think is truly a breakthrough in understanding of the disorder. Even though it may sound well outside the realm of how the scientific community might explain or describe something, and relies on a great deal that is known to me, but not necessarily the modern scientific community, it represents a breakthrough nonetheless…. Read more »


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Maine's new Legislature has been sworn in - and it includes several who are new to the job. MPBN Morning Edition host Irwin Gratz captured the impressions of four rookie lawmakers from both parties as they begin learning the ropes of state policy-making.
We're going to introduce you now to four legislators with one thing in common: None has ever served in the Legislature before.
"Hello, my name is Tim Marks. I'm the District 53 representative from Pittston, Dresden, Alna, Wiscasset."
"Hi. I'm Christine Powers (left, with her mother, displaying her legislative license plate). I'm a new state representative from Naples, serving Naples, Casco and part of Poland.
"My name is Carol McElwee, and I'm from Caribou, Maine, and this is District 4 that I represent. And that's in Aroostook County."
"I'm Jim Boyle. I represent the voters of Gorham, Scarborough, part of Westbrook - it's Senate District 6."
McElwee is a Republican, Marks, Powers and Boyle Democrats. There'll be time later for them to stand-up and be counted in possibly partisan struggles over budget, tax and other bills. Instead, we'll hear them talk, today and tomorrow, about their first impressions as they join the ranks of lawmakers.
We'll hear more from the new lawmakers Thursday, Dec. 13, on Morning Edition.
Photo by Irwin Gratz.


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The Pew Charitable Trusts is driven by the power of knowledge to solve today's most challenging problems. Pew applies a rigorous, analytical approach to improve public policy, inform the public and stimulate civic life.
Apr 24, 2012
With a Florida judge clearing the way for George Zimmerman to get out of jail on bail, developments in the case against the man charged in the killing of Trayvon Martin topped Americans' news interest last week.
About a quarter of the public (26%) says they followed developments in the case more closely than any other news, according to the latest weekly News Interest Index survey, conducted April 19-22 among 1,004 adults by the Pew Research Center for the People & the Press. The controversy over the shooting of Martin, an unarmed African American teenager, has now been the public's top story for five straight weeks.
Coverage, though, dropped to 7% of the newshole from 17% the previous week, when Zimmerman was arrested and charged with second degree murder, according to a separate analysis by the Pew Research Center's Project for Excellence in Journalism (PEJ). The 2012 presidential campaign received the most coverage last week, accounting for 17% of the newshole.
Read the full report, News about Trayvon Martin Case Still Top Story, on the Pew Research Center for the People & the Press' website.
The Pew Health Group's new Web site informs and engages people about issues that affect their health and well-being.
Spring 2012
Read articles on improving elections, the changing news environment, improving school lunch standards, and more.
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Shedding Light is the Virginia Wills, Trusts & Estates weblog. I will post here regularly, focusing on those areas of the law that I address every day in my law practice, namely estate planning, probate and the settling of estates, the federal estate and gift tax rules, and adoptions. My goal is to shed light into murky areas. I'll also post your comments as they are received. I have been advised to confine my snarky political posts, Red Sox rants, cultural observations, cute pictures of my kids, and my Walter Mitty daydreams to my Facebook page. If you must see them, friend me.
Tom Nolan


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Phase I Drug Trial for S/E of Marimastat in Disabling Malformations When no Other Options.
This study has been completed.
Children's Hospital Boston
Information provided by:
Children's Hospital Boston
ClinicalTrials.gov Identifier:
First received: December 2, 2005
Last updated: January 8, 2008
Last verified: May 2005
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
3 patients were enrolled in each of 3 study cohorts. There three cohorts were given differing, incrementally larger doses of this phase I drug. The same safety measures are being obtained on all patients. Efficacy measures were individualized as enrolllees do not have the same underlying vascular anomaly. The study is structured to include a 24 month drug-phase and a 24 month follow-up phase. The study is now closed to enrollment.
Vascular Anomalies
Drug: Marimastat
Phase 1
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Phase I Dose Escalation Study to Evaluate the Safety and Preliminary Efficacy of Marimastat in Patients With Disabling Malformations and No Other Treatment Options
Resource links provided by NLM:
Genetics Home Reference related topics: capillary malformation-arteriovenous malformation syndrome Parkes Weber syndromeU.S. FDA Resources
Further study details as provided by Children's Hospital Boston:
Primary Outcome Measures:
- History
- Physical Examination
- Laboratory studies
- Vital Signs
- Urine studies
Secondary Outcome Measures:
- Individualized. Change in the predetermined measure of the vascular anomaly.
|Estimated Enrollment:
|Study Start Date:
|October 2000
|Estimated Study Completion Date:
|October 2007
|Ages Eligible for Study:
|2 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
Patient with vascular malformation causing risk of one or more of the following based on unanimous assessment of designated physicians in the multidisciplinary Vascular Anomalies Team.
- airway/respiratory/visual/auditory/neurologic compromise;
- high output cardiac failure;
- life-threatening or disabling hemorrhage(cutaneous/GI/intracranial/ parenchymal/cavitary);
- skeletal distortion/destruction/erosion;
- life-threatening or disabling soft tissue distortion or destruction
- Patient must be felt to have failed, be unable to significantly benefit from, or be at risk for other available therapies, including surgeries, embolization, and sclerotherapy based on unanimous assessment of designated physicians in the multidisciplinary Vascular Anomalies Team.
- Patient must be felt to have one or more physical, imaging, photographic, physiologic or other measurable features that can be measured on a regular basis for preliminary evaluation of efficacy. The feature(s) must be agreed on by the designated physicians in the multidisciplinary Vascular Anomalies Team).
- Signed Patient informed consent.
Exclusion Criteria:
- Pregnancy
- Patient nursing child.
- Female patient of childbearing potential unwilling to receive contraceptive counseling and use reliable contraceptive method.
- Patient enrolled in any other clinical trial involving an investigational agent (unless approved by the designated physicians on the multidisciplinary team)
- Parent or guardian or child unwilling to provide consent or assent.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00261391
|United States, Massachusetts
|Childrens Hospital
|Boston, Massachusetts, United States, 02115
Sponsors and Collaborators
Children's Hospital Boston
|Principal Investigator:
|Steven J Fishman, M.D.
|Children's Hospital Boston
More Information
No publications provided
Keywords provided by Children's Hospital Boston:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on April 17, 2014
No publications provided
|ClinicalTrials.gov Identifier:
|NCT00261391 History of Changes
|Other Study ID Numbers:
|Study First Received:
|December 2, 2005
|Last Updated:
|January 8, 2008
|Health Authority:
|United States: Food and Drug Administration
Keywords provided by Children's Hospital Boston:
Arteriovenous Malformation
Lymphatic Malformation
Additional relevant MeSH terms:
Congenital Abnormalities
Vascular Malformations
Cardiovascular Abnormalities
Cardiovascular Diseases
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
ClinicalTrials.gov processed this record on April 17, 2014