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Shop Mindfully, It's Worth the Hassle
With collectibles, it is never "I came, I saw, I bought". Nor should it be. The "snap of the fingers" shopping method will do for products of mass consumption, especially the products that are meant to last until a newer model comes along.
However, when you go shopping for collectibles, you have to really put your whole being into it, whether you do it for the sheer pleasure of collecting or for investment purposes.
What goes for collectibles in general goes for rare coins too; perhaps even more so, because the world of coin collecting is so vast and complex. As a beginner collector, your aim is to buy rare coins that are genuine, well preserved and worth the price tag.
Online marketplaces like bidorbuy offer possibilities that collectors could not even dream of only a couple of decades ago. It is now possible to research, compare and buy, all from the comfort of one's home.
Before you even start window-shopping, it is necessary to acquire at least a rudimentary knowledge about the coins that you are interested in. For example, if you want to focus on ZAR coins, you need to know which ones are considered extremely scarce and which are available in decent quantities. It is advisable to have a current coin price guide handy. They are very helpful both in determining coin values and keeping track of the changes in the coin market.
You should also know that "well preserved" does not mean cleaned. On the contrary. A coin that has been cleaned or altered in any way loses a great deal of its value, if not all of it. Cleaned coins have a washed-out, pasty look, lack tone and hairlines. Any changes on the coin from its mint state should only be due to normal wear and tear.
Unfortunately, it is very difficult to tell from an image in a listing whether the coin you want to acquire has been tampered with or not. To make sure that your purchase does not fall sour, you may decide to buy only coins graded by reputable grading companies, like the American PCGS and NGC or the South African SANGS.
But what if you come across a really tempting un-graded coin?
Your best option here is to pose probing questions to the seller. Of course, on bidorbuy you cannot contact the seller directly before you buy from her or him. The way to go about this is to open the listing of the coin you are interested in and click on Ask the seller a question link.
Also, always check whether the seller offers a return policy. This is especially important in the case of coins that have not been graded. You may still lose some money on shipping the item back, but that is usually a negligible amount.
It goes without saying that buying from sellers who have a good trading record on bidorbuy is your best protection against disappointment.
The majority of rare coins to be found on bidorbuy are listed in the auction format. Sometimes, a seller will put a secret reserve, thinking that the lower opening bid will attract more bids. In reality, very often the opposite happens: as soon as they see "reserve", buyers tend to walk away…. which opens a window of opportunity for you. On bidorbuy, the difference between the publicly stated opening bid and the secret reserve can be up to 20%. No more. So, if the opening bid is R2500 and there's a reserve, you will know that the secret reserve can be between R2500 and R3000.
Once armed with the reserve amount, you can plan your bidding strategy. If the reserve amount seems to be reasonable, you can place your bid. To make sure that you do not pay more than the seller is willing to sell the item for, place an auto bid on the maximum reserve (R3000). If the reserve happens to be lower and no one else places a higher bid – you will have won the auction!
When bidding for rare coins on auction, different collectors have different strategies. The important thing is to do your research and decide on the top price you are willing to pay, even if you want a particular coin badly. That way, you'll never suffer from buyer's remorse.


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Daily Meditations for Calming Your Anxious Mind
- United States
- Self-Development
- English
More informationTrying to control your anxious thoughts can backfire, making them more prevalent, not less. The best way to calm these common feelings is by attuning yourself to your thoughts in a nonjudgmental, attentive manner, acknowledging your anxieties but choosing to act rather than react.
From the author of Calming Your Anxious Mind comes Daily Mediations for Calming Your Anxious Mind, a collection of more than 60 daily mindfulness-based guided meditations to help you engage with the present moment, manage stress and anxiety, and rediscover the joy in living. Each guided meditation contains an easy-to-learn visualization exercise, affirmation, or activity, with meditations grouped into four sections: relaxing and feeling safe, embracing joys and fears, befriending your anxious mind and body, and connecting to the web of life. You'll return to this collection of meditations again and again!

subset: commoncrawl


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Admire the most beautiful places of Gagliole and add them to your basket. YAMGU will create your trip considering distances, opening hours and weather.
In the Centre of the seat, Gagliole natural history museum; a museum exhibiting fossils and minerals are preserved, showing the evolution of life on Earth. The show follows a chronological itinerary, starting from Archeozoica, through all eras and all periods in which the same were divided, until today.


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1000 Words
On Krrb, a photograph is most often the first way that we encounter any given item that is up for grabs. And many of these pictures are quite striking in and of themselves. Which is what makes scrolling through Krrb listings so compelling, and why we wanted to give props to the images that catch our eye and keep us looking long after we've decided whether or not we need another, say, nun mask in our lives. We will post these often, so check back and watch the collection grow.


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Published on Amazon? If you have a book, e-book, or audiobook available on Amazon.com, we'll promote it on WritingForums.org for free. Simply add your book to our Member Publications section. Add your book here or read the full announcement.Dismiss Notice
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My kid is awesome :D
Published by Trish in the blog Trish's blog. Views: 161
Okay, so actually BOTH of my kids are awesome, but since today is my son's tenth birthday it's all about him I actually can't believe he's ten. It doesn't seem so long since I was the center of his world and the only one who knew just what to do to make him happy (I left his father when he was only 3 months old and it was just me and him for a long time). He's still the center of mine, of course, both of them are, but now that he has the ability to talk, to read, a larger vocabulary than me, pretty much anyone can "get" him, lol. He's brilliant, and I'm not just saying that because I'm his mom, but because he truly is. He's the most intelligent child I've ever had the pleasure of knowing. At the age of eight he started researching the Civil War, because he wanted to know. He can explain how airplanes work, why tsunami's and hurricanes exist, and how volcanos erupt. He's an endless sponge, and I've learned so much from him, with him.
Last year he got a PERFECT score on his ELA exam. No one else in his school did, let alone his grade. He wants to be an architect, and he has ADHD. You probably wouldn't know it since he controls it so well. He asked to be taken off of meds two years ago, didn't like them. I respected his reasons, we discussed it, he's been off of them ever since.
He has the most engaging smile I've ever seen. When he smiles you can't help but smile back, blue-green eyes on fire from a soul burning so brightly inside you think he'll be consumed by it. He needs to KNOW. EVERYTHING. He goes through books like other kids go through candy. He's as tall as me, lol. Yeah, I'm short, but he's only ten, he's going to be so tall.
He loves to go fishing He drew this picture this morning before school (only about an hour) and it doesn't show up the greatest, but I think you get the drift. The best part is it's about 4 feet long by 2-2 1/2 feet high. (Don't mind my floors, please, my house was built in 1791 and the floors are original. I haven't had the $$ to refinish them yet.)
This is the bunny he drew for his sister real quick on saturday... too cute
I don't know what the hell I've done right to deserve these children, but I'm so glad I did. They're my whole world.
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Lolli Swim Lovely Bottom - Honey Girl
Lolli Swim
The Lolli Swim Lovely Bottom in everything! Since we first saw Sofia Jamora rocking this bikini at Swim Week we have been obsessed with it. This bottom is made of ribbed textured fabric with sassy lace up sides. The bottoms are high waisted and provide cheeky to Moderate coverage. Wear it with the Dandy Top in Honey Girl if you really want to slay everyone's life.
Lolli Swim 2017 Collection
Also available in Black <3
- Lovely Bottom in Honey Girl
- Adjustable lace up sides
- High waisted
- Cheeky fit
- Moderate coverage
- Sofia is wearing a Small


text: To get from Grottaglie to Comiso by train you can catch one of the 2 trains that everyday travel between these two cities. The first train to Comiso leaves from Grottaglie at 08:35 and the last train departs at 21:30. If you choose a local train the trip lasts on average 01:27 hours. For your trip from Grottaglie to Comiso by train you can choose to leave from one of Grottaglie main stations: Grottaglie On Wanderio you can compare all schedules, fares and railway companies to Comiso and book the best itinerary starting from Grottaglie.


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Strut King 02-06 RSX Automatic Pedal Set
Free Shipping
Inside Continental United States
Please contact us for availability
Earn 178 reward points. Learn More
Will It Fit Your Vehicle?
Fitment NotesFor Automatic Transmissions Only
The RSX sport pedals combine the modern elegance of brushed stainless steel with traditional rubber grip to blend beauty with function.
These sport pedals were designed specifically for the RSX by complimenting interior elements. Bring new life to your interior by wrapping your pedals in brushed 304 stainless steel, custom formed to fit your car perfectly. The brake and clutch utilizes rubber inserts to ensure grip under any weather conditions and are corrosion resistant.
All hardware is included for easy installation. A power drill is needed for proper installation.
Fits ALL years RSX & RSX type-S and UK Civic EP3 (RHD)
For LHD UK Civic EP3's, please see the Civic 01-05 pedal sets
For Manual Transmissions
What's Included:
Sport Pedal Set (includes footrest)
Necessary hardware for install
Required Tools:
Power drill
7mm socket wrench
Phillips screwdriver
Install Instructions
- Part Number: SK06-HPDL-RAT02
- Color: Stainless Steel
- Manufacturer: Strut King
- View instructions
- Difficulty:
Vehicle Fitment
- For Automatic Transmissions Only
- Acura RSX
- 2002 Acura RSX Automatic
- 2003 Acura RSX Automatic
- 2004 Acura RSX Automatic
- 2005 Acura RSX Automatic
- 2006 Acura RSX Automatic
Customers Also Bought
3 reviews for Strut King 02-06 RSX Automatic Pedal Set
5.0 out of 5.0
11/1/2015 by DC5 dave
nice pedals
Fairly easy install. Looks great makes it look sporty
1/25/2012 by justin archangelo
Clean pedals
Makes interior look alot better and better grip for the feet, really easy to install just need drill and takes 5 minutes. well worth the money.
10/17/2010 by Trill
gives the interior a clean look and more grip over stock, installation wasn't hard u just need a drill


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Uta no Prince-sama clear file holder NATSUKI&SHO promo official new!
- Sold for: Start Free Trial or Sign In to see what it's worth.
- Item Category: Entertainment
- Source: eBay
- Sold Date: Jun 05, 2012
- Channel: Auction House
�� Commodity explanation ��
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Edwin Outwater is in his ninth season as Music Director of Ontario's Kitchener-Waterloo Symphony, is Director of Summer Concerts at the San Francisco Symphony, and regularly guest conducts the Chicago and New World Symphonies. Equally at home interpreting canonical masterworks, premiering new works, and creating truly innovative, audience-building programming initiatives, the American conductor is, as San Francisco Classical Voice recently observed, "headed for a top-tier future."
In the United States, Outwater has conducted the New York and Los Angeles Philharmonic Orchestras, as well as the symphony orchestras of Chicago, Baltimore, Houston, Detroit, Indianapolis Seattle, Phoenix, North Carolina, Milwaukee, Alabama, the New World Symphony, and many others. In Canada, he has conducted the National Arts Centre Orchestra, as well as the symphonies of Toronto, Calgary, Edmonton, Winnipeg, and Victoria. International appearances include the Tokyo Symphony, Tokyo Metropolitan Orchestra, the BBC National Orchestra of Wales, the New Zealand Symphony, the Adelaide Symphony, the Malmö Symphony, the Nordwestdeutsche Philharmonie, the Mexico City Philharmonic, the Orquesta Sinfónica de Xalapa, and the Hong Kong Sinfonietta. He has collaborated with Yo-Yo Ma, Evelyn Glennie, and many others.
In 2009, he made his professional opera debut with the San Francisco Opera conducting Verdi's La Traviata, and he has since conducted Piazzolla's María de Buenos Aires with concert:nova Cincinnati and the Cincinnati Opera, as well as Menotti's one-act opera Amahl and the Night Visitors at New York's Lincoln Center. He participated as Associate Conductor in both YouTube Symphony projects, at Carnegie Hall and the Sydney Opera House.
Outwater was Resident Conductor of the San Francisco Symphony from 2001-2006. While there, he worked closely with Michael Tilson Thomas, accompanying the orchestra on tour and conducting numerous concerts each season. From 2001-2005, Outwater was Wattis Foundation Music Director of the San Francisco Symphony Youth Orchestra. During his tenure, he led the orchestra in all of their concerts as well as on tour through Europe in summer 2004, when the orchestra made its debut at Vienna's Musikverein and Paris's Théâtre des Champs-Élysées, and returned to Amsterdam's Concertgebouw. Before joining the San Francisco Symphony, Outwater served as Resident Conductor and Associate Guest Conductor of the Florida Philharmonic. He has held posts as Associate Conductor of the Festival-Institute at Round Top in Texas, Principal Conductor of the Adriatic Chamber Music Festival in Molise, Italy, and Assistant Conductor of the Tulsa Philharmonic.
Outwater's work in music education and community outreach has been widely celebrated. In 2004, his education programs at the San Francisco Symphony were given the Leonard Bernstein Award for Excellence in Educational Programming, and his Chinese New Year Program was given the MET LIFE award for community outreach. In Kitchener-Waterloo, Outwater redesigned the orchestra's education series and initiated myriad community connections. In Florida, Outwater designed the Florida Philharmonic Family Series and its Music for Youth program. He appears frequently with training orchestras and music festivals throughout the United States and across the world, including the New World Symphony, the Civic Orchestra of Chicago, the National Music Camp of Australia, the National Youth Orchestra of New Zealand, the Music Academy of the West, the National Orchestral Institute, the Festival-Institute at Round Top, and New York's Mannes Conservatory Orchestra. Outwater has served as music director of the Santa Barbara Youth Symphony and on the faculties of the University of Tulsa, Idyllwild Arts Academy, and University of California, Santa Barbara.
A native of Santa Monica, California, Edwin Outwater attended Harvard University, graduating cum laude in 1993 with a degree in English literature. While at Harvard, he was music director of the Bach Society Orchestra and the Harvard Din and Tonics (an acclaimed a cappella group), and wrote the music for the 145th annual production of the Hasty Pudding Theatricals. He received his master's degree in conducting from the University of California Santa Barbara, where he studied with Heiichiro Ohyama and Paul Polivinick. He also studied music theory and composition with John Stewart, Joel Feigin, and Leonard Stein.


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Arte di Mano Sughero Neck Strap - Rally Bordo
The Arte di Mano Comodo Sughero SLR-style neck strap is perfect for your Leica S or SL system camera. "Suhero," Italian for "cork," describes the soft, high-density foam used to pad the 1.5-inch (38mm) shoulder section of the necks strap. The foam is sewn between a layer of fine leather and Nubuk to offer the maximum comfort possible when carrying your camera. The strap is adjustable offering a length range of approximately 32" - 60" (76-152cm).
About the Leather: Rally Bordo by Ausonia is a soft vegetable-tanned red leather with a weathered look. The red leather perfectly matches the red dot on your Leica!
About Arte di Mano: Arte di Mano, a brand created by JnK in Seoul, South Korea has become synonymous with quality. Their half cases for the Leica M, X, T and Q systems are made entirely by hand. Each piece of leather is carefully cut, shaped and stitched to create a flawlessly-fitting half case that improves your hold without hindering any functionality of the camera.
**Due to the properties of the leather and the handmade nature of Arte di Mano products, each neck strap is unique and may vary slightly from the item pictured.**
- For use with SLR-style camera including S and SL system cameras
- Soft, padded Nubuk-lined shoulder section.
- Adjustable length from ~32-60in (76-152cm)
- Cream-colored stitching
- Soft, vegetable-tanned red leather


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This section updates the report produced last year (OTO/2001/055) in which all releases reported in 2000/01 were investigated as part of the Process Integrity Initiative (See Appendix 1).
There were 241 reportable releases in 2001/02, of which 47 investigation reports were received for analysis, representing 21% of the total. These have been analysed according to the taxonomy presented in table 5 of last year's report. The following conclusions can be drawn from this sample.
Again pipework accounts for the majority of releases, 62%, this is comparable with last year's 61%. However, there are some differences within this grouping between this year's analysis and that of last year. A greater proportion of this year's release sites have been assigned to small bore pipework and associated connections, including instruments, 25% as opposed to 18% last year. Perhaps of more significance is the marked reduction in releases from pipe open ends, down from 16% to 4%. Valves were involved in 21% of releases, vessels 6% and pumps 6%.
Other findings:
The information provided in the hydrocarbons release database also records the location of release albeit using a different coding framework from that used in OTO 2001 055 (see table 14). This confirms that in most respects the sample of investigated reports is representative of the location of releases for the whole set of 241 releases. Releases from instrument (22%) and pipework (22%) dominate. These results reflect the indication from the sample that there is a slight change towards instrument releases and away from pipework compared to last year's data.
There were only 12% of releases from valves in the full data set which is in line with last year's results and indicates that the sample of investigated reports has a higher proportion of these types of release (21%).
The other main difference is in relation to releases from flanges. The sample includes 15% of these releases which is a greater proportion than the whole 241 releases which only had 7% flange releases.
There were no hose releases investigated this year. However, 3% of the total releases were from hoses, this was in line with 4% of releases last year.
As last year, the largest single cause was degradation of material properties which accounted for 28% of the incidents, comparable with last year's 26%. Incorrect installation at 21% and fatigue/vibration also 21% were the second largest contributors. Both of these are almost double last year's figures of 12% and 11% respectively, and more significant than corrosion/erosion which accounted for 13%, this is a drop compared to 19% last year. Procedural type causes were all less than 10%.
A check against the full set of 241 releases on the HCR database shows good agreement for erosion/corrosion causes. The full set of data shows an even greater contribution from mechanical failure and wearout which together account for 36% of the total, whereas fatigue accounted for 12% of the total. Incorrectly fitted at 7% of the total is the most frequent of the procedural failures. Although the percentages differ between the sample and the full set of data, the two sets of data give the same indication of the most prevalent immediate causes, despite using different causation frameworks. One interesting result from this comparison is to confirm the finding that in this year's releases, a much smaller proportion were due to releases from open end of pipes or valves compared to last year. This is confirmed by the causes "left open" or "opened with hydrocarbon present" which accounted for 7% of releases. This is in line with the 10% of "open end" releases in the sample which is a reduction compared to the 20% of such releases occurring last year.
Degradation of material properties is taken to mean loss of integrity by failure of equipment that was originally fit for purpose and has been operated correctly. This includes failure of flange gaskets and valve packings and might be termed general "wear and tear". It excludes the more specific causes of failure such as corrosion, erosion, fatigue and vibration. Unlike last year, three of the four major releases had immediate causes of degradation of material properties and only one was due to operator error. Although four is too small a number to draw any far-reaching conclusions.
When it comes to analysis of the most important release sites, the most prominent cause for flange leaks (15% of all releases) was incorrect installation in 60% of cases, which is a significant increase compared to last year. Degradation of material properties was much less significant at 15%. For small bore tubing and associated connections (25% of releases) fatigue accounts for 33% of causes, incorrect installation a further 25% and degradation of material properties 17%. This is in line with last year's findings although incorrect installation plays a more prominent role. Open ends only account for 10% of releases in this analysis. The causes are evenly distributed although most are procedural rather than hardware related, which is not really surprising.
The immediate causes can be divided into hardware or software related as follows:
62% of releases had hardware related immediate causes, of these the underlying causes were mainly inadequate inspection/condition monitoring in 48% of these incidents. The next most significant underlying cause was inadequate design (34%).
The remaining 38% of releases had software related immediate causes, of these the causes were mainly inadequate procedures (40% of these incidents), the next most frequent cause was inadequate compliance (28%).
The underlying causes of many incidents are complex and more than one cause can be identified in many cases. When these are analysed independently of immediate cause, the largest contribution was from inadequate inspection/condition monitoring in 32% of investigated incidents, closely followed by inadequate design 30%. These are very similar to last year's figures of 28% and 29%. The next four most significant underlying causes were inadequate procedures in 23% of incidents, incorrect installation 15%, incorrect material specification/usage 13% and inadequate risk assessment 13%. Other underlying causes were identified in less than 10% of investigated incidents.
Comparison with last year's analysis reveals that the same two underlying causes dominate but that there is a slightly different contribution from the other causes. Excessive workload, inadequate communication, outdated information and inadequate task specification again made little or no contribution.
As with last year's analysis, inspection/condition monitoring was the most prevalent failed safeguarding system that might have prevented the release of 30% of all incidents investigated. Of the remaining safeguarding systems, competency assurance was the next highest with corrosion/erosion monitoring and change control also featuring. Design review was less significant than in last year's analysis.
There was no identifiable pattern for major releases.
The UKOOA small bore piping guide continues to be relevant, in 23% of investigated incidents. But in this year's analysis, the flange verification scheme was less relevant, only in 4% of this sample.
The sample of investigated releases shows similar results to the analysis of a larger sample from last year. Where there are changes identified it is difficult to be certain that these are real differences or whether they arise from a different interpretation of some of the coding. However, this analysis indicates that important lessons can be learned from analysis of investigation reports, over and above the information that is available from the Hydrocarbons release database.
The results indicate that conclusions drawn from the previous analysis are still valid and therefore the focus of the process integrity intervention project should continue. In order to identify any real change in the causes of hydrocarbon releases, analysis of a larger sample would be necessary which perhaps points to collection of more investigation reports during the remaining years of the project. This information would also be of use in demonstrating the impact of the intervention, not only in driving down the number of releases, but also in tackling some of the immediate and underlying causes.
Appendix 1 of this report outlines the framework for the OSD Process Integrity Initiative aimed at raising industry awareness of offshore hydrocarbon releases and the need for their reduction. The initiative is structured around 10 key elements that could contribute to the prevention of hydrocarbon releases. Not all elements are applicable to all installations and some elements are of lesser direct impact for releases for many installations. OSD have conducted process integrity inspections on manned production installations commencing in the year 2000.
To the end of 2002, inspection progress has been made on 87% of installations covered by the initiative. The greater activity has been on 7 of the 10 elements that have larger direct bearing on potential releases. These include issues such as process integrity management, documentation and change control, and design and operational issues including isolation & PTW, small bore pipework, plant protection systems and maintenance & verification of safety critical elements. Around half of all possible inspections across all installations in these 7 elements have been completed. Work has also progressed on the remaining elements.
HSE has kept the offshore industry informed of key findings emerging from inspections via joint HSE/industry workshops held at staged points throughout the project (Appendix 1). As information has been passed on, emphasis has moved towards the current position of development of remedial programmes by dutyholders to target their high risk areas and activities. During the coming year, HSE will be targeting efforts towards the poorest performing companies, as measured by the number of releases per manned production installation (see Table 15 in Section 5.0).
OSD will use the existing data on offshore hydrocarbon releases to target inspections on dutyholders and installations that appear to have, in recent years, the poorest performance. This is intended to focus inspection resources towards areas of highest risk, in line with HSE policy. The inspections will use analysis of incident investigations and other sources of information to identify topics for particular attention. Any findings of non-compliance with regulations that arise from the inspections will result in enforcement as set out in existing HSE and OSD policy.


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nophonetrees.com was registered 1 decade 1 year ago. It has a alexa rank of #1,054,573 in the world. It is a domain having .com extension. This site has a Google PageRank of 3/10. It is estimated worth of $ 720.00 and have a daily income of around $ 3.00. As no active threats were reported recently, nophonetrees.com is SAFE to browse.
|Daily Unique Visitors:
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|$ 3.00
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|$ 720.00
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GhFitlab is Chicago's leading personal training company delivering scientifically precise exercise with amazing results. Get a free session today.
|Domain Registrar:
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|Profit Loss Account Reserve
|£ 539,685
|Called Up Share Capital
|£ 25,800
|Net Assets Liabilities Including Pension Asset Liability
|£ 568,490
|Net Current Assets Liabilities
|£ 143,862
|Creditors Due Within One Year
|£ 11,025
|Cash Bank In Hand
|£ 11,738
|Stocks Inventory
|£ 38,359
|Par Value Share
|5% Preference Shares of £1 each
|Number Shares Allotted
|£ 25,800
Information about the Private Limited Company W.G.C.HAMMOND,LIMITED has been prepared for information purposes only. It is not intended to be nor does it constitute legal advice. This is public information provided by the official company register.


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The term lateral epicondylitis—often referred to as "tennis elbow," is a condition marked by small tears in the tendons that surround the elbow area. These tears occur on the outside of the elbow and do so because of cumulative and on-going trauma that is caused by repeated use of the arm and forearm muscles. Athletes and sports enthusiasts who play tennis are at a higher risk for developing lateral epicondylitis. The pain and tenderness associated with medial epicondylitis or "golfers elbow" will occur on the inside of the elbow and will intensify when lifting, extending or making a fist.
For individuals who play tennis or similar activities every day, bone strength, the right technique and decreasing the intensity of play can oftentimes help keep tennis elbow at bay.
Symptoms of Lateral Epicondylitis
Tennis elbow can create a great deal of pain, usually on the outside of the elbow. Lifting objects, gripping and turning the arm will be difficult to do. For some, the pain will radiate up and down the arm while for others the pain will stay primarily in the elbow itself.
Treatment for Tennis Elbow
As with many sports-related injuries, RICE is typically the first form of treatment that Dr. Millett will recommend. RICE stands for rest, ice, compression and elevation. If the injury is related to overuse of the wrist, eliminating the activity all together for a duration of time will often heel the injury. Over time, physical therapy might also be required to help strengthen the elbow. In some cases, a splint or brace will be recommended.
Surgery to repair medical epicondylitis: If left untreated, tennis elbow may require surgical intervention. Dr. Millett will likely perform arthroscopic elbow surgery to repair the torn tendons. The procedure is a minimally-invasive, out-patient surgery that is most often a successful course of treatment for the patient.


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Cheryl's story is heartbreaking. It must have been horrific to have lost your use of words. The rings are lovely! From adversity comes strength, hope and courage.
Cheryl, if you decide to branch into 5-letter word rings, why not use "faith" as another "bit of love" ring. You certainly had the faith to overcome your difficulties.
This is an incredible story. I had Lyme growing up, but thankfully it was caught early. On Long Island it is such a real problem and I know women who had so many physical problems after the disease had been in their bodies for several years. This is a very powerful story though of someone turning a bad thing into something good than can really touch others. Thank you for sharing!
"Bits of love" hold the world together, don't they? Cheryl, bravo to you and to your tenacity to keep moving forward and find the "just right" creative expression for those powerful words. Your steadfast mother always knew you would figure out something amazing with your gift with words.
Thanks, all! And thanks, Libby. You nailed it with "steadfast" to describe my mom. She's definitely seen me through all the ups and downs with wonderful, inspiring words to keep me me going. Thanks for your kind words.
Such great Lyme-Ade!
Thank you so much for your encouraging words. I have been significantly ill with chronic lyme for many years, and though healing, It is still an uphill battle…it is comforting to hear experiences from others who have been down a similar path.
Thanks for your comment, Becca! I definitely hope you get to the top of the hill with your struggle with lyme. I remember all the oddities lyme likes to toss into the mix that made me question if one disease could create so many symptoms. If I can ever be of any help with additional details on my experience, please don't hesitate to email me at [email protected]. I know the stories of people who recovered before me are what kept me positive and refueled my fight against lyme. Here's to your continued recovery!
Pingback: Women You Should Know 186 People Rose With WYSK For Girl Rising()
I loved this story and will share on our blog career2.0blog.net about inspirational stories of women starting new careers. It reminds me of our post on a Swiss woman, Christine Bienvenu, who launched a social media platform for French-speaking cancer patients. Diagnosed with triple negative breast cancer the young mom-of-two faced a dearth of community and online support in her mother-tongue, so she simply created it – as much for herself as for others going through a similar situation. You can read her story at http://career2.0blog.net/2014/06/03/christine-bienvenu-reinvention-in-the-face-of-adversity/


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In an analysis of data collected from the PATHOS trial and published in the Journal of Internal Medicine, researchers found that COPD patients treated with Symbicort Turbuhaler (budesonide/formoterol) are significantly less likely to experience COPD exacerbations and to be hospitalized for COPD than those treated with Advair (fluticasone/salmeterol), also known as Seretide.

The PATHOS trial, conducted in Sweden over an 11 year period, analyzed medical records of 5,468 patients treated with an inhaled corticosteroid (ICS) and a long-acting beta agonist (LABA) between 1999 and 2009. Two groups of patients were formed: One group was treated with budesonide/formoterol with an equal number of patients treated with fluticasone/salmeterol. For the purpose of the study, exacerbations were defined as some form of medical intervention, including hospitalizations, emergency room visits, and prescriptions of oral steroids or antibiotics due to a worsening of COPD.

Overall, being treated with budesonide/formoterol reduced the yearly rate of moderate-to-severe exacerbations by 26% compared with fluticasone/salmeterol. This reduction was apparent for all exacerbation events, such as antibiotic use, oral steroid use or admission to the hospital. Additionally, treatment with budesonide/formoterol reduced the yearly rates of COPD-related hospitalizations by 29% and hospital days due to COPD exacerbation were 34% fewer compared with fluticasone/salmeterol.

Study findings reveal the impact that these two treatment combinations have on patient outcomes, providing valuable information to health care providers, patients and insurance companies.

If you have COPD, have frequent exacerbations that require medical intervention, and are taking another ICS/LABA combo, talk to your doctor today about whether you might benefit from making the switch to Symbicort.

Source:

Astra Zeneca. Real world study comparing commonly prescribed COPD medicines shows choice of treatment has impact on patient outcomes. 19 March 2013.


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Clinch Gear Signature Long Sleeve Tech Top Black
Signature Series Technical Tops features state of the art fabrics and construction for optimum performance.
They have breathable stretch mesh lateral inserts on each side for comfort and accelerated moisture wicking, and a high stretch polyester compression impact area on the front and back.
The rear Drop Back offers an ergonomic fit to reduce the garment from riding up above the waistline.
Clinch Gear Signature Series Technical Tops incorporate the highest quality flat lock stitching on all seams for durability and breathable, moisture wicking fabrics for reduced weight, increased comfort and maximum performance.


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Munchkin' Sports
April 26, 2017
Belle Terre Park, 339 Parkview Drive, Palm Coast
April 19-May 24 – Munchkin' Sports – Wednesdays, April 19 through May 24, 5:15-6 p.m. at Belle Terre Park, 339 Parkview Drive, Palm Coast. Children ages 3-5 learn the basic motor skills necessary to play organized sports such as soccer, baseball, golf, football and tennis. The six-week program is set up for parents to assist during lessons to enjoy quality family time. $35 per session. Must pre-register by 5 p.m. April 17 (while space available): www.palmcoastgov.com/register. More info: 386-986-2323.
Other Events
Speech & Debate by Stephen Karam June 22nd - 25th
June 22, 2017
The Baiata Bird Sanctuary Cage Sale June 23rd and 24th!
June 24, 2017
The Flagler Women's Club Bunco Night!
June 24, 2017
Adult Bible Stories: All are welcome!
June 25, 2017


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Articles tagged star wars
23 May 2017 // 8:53 AM
Star Wars, George Lucas said back in 1975, two summers before its release, "is built on top of many things that came before".READ more
17 Apr 2017 // 10:27 AM
After four days at Star Wars Celebration you start to feel knee-deep in Sith.READ more
3 Aug 2016 // 9:30 AM
What made George Lucas such a cinematic visionary is also what's making him less effective as a civic figure.READ more
12 May 2016 // 10:30 AM
C-3PO's red arm evidently carries more weight than its metal.READ more
12 Feb 2016 // 3:05 AM
This is a visually stunning display of concepts, characters and starships from a galaxy far, far away that, more often than not, didn't even end up on screen.READ more
11 Feb 2016 // 11:45 AM
Jason Aaron provides another glimpse of Obi-Wan's years on Tatooine. But who has he become?READ more
5 Feb 2016 // 9:00 AM
- //Multimedia
- //Blogs
- //
Sometimes "shallow" and "uncomplicated" is exactly what I'm looking for in a game.READ more
21 Jan 2016 // 3:30 AM
Star Wars is the latest exemplar of a genre that's accelerating toward its own creative exhaustion. That genre, of course, is the Hollywood tent-pole.READ more
New 'Star Wars' Film Is a Fascinating Insight into the Populist Artistry of Its Veteran Screenwriter
6 Jan 2016 // 9:54 AM
The rehabilitation of the Star Wars franchise is a triumphant return for Kasdan, whose output since the start of the millennium has been as underwhelming as that of, well, George Lucas.READ more
30 Dec 2015 // 11:51 AM
Josh Rottenberg and Steven Zeitchik talk about the series, sussing out the cultural legacy of and reactions to the new film, the larger context of franchise revivals and where Star Wars goes from here.READ more
23 Dec 2015 // 8:00 AM
Vesa Lehtimäki's collection of photographs featuring LEGO toys in inventive situations is an inspiring and innovative collection.READ more
16 Dec 2015 // 11:30 AM
J.J. Abrams's sleek, feverishly hyped Episode Seven injects the moribund series with humor and humanity, but relies too much on remixed bits from the original trilogy.READ more
'Star Wars: The Force Awakens' is destined to be big, but can rival films follow it into hyperspace?
9 Dec 2015 // 10:29 AM
That "The Force Awakens" will reap massive returns for its studio, the Walt Disney Co., is undeniable. What is less clear is what sort of ripple effects the film will have on the wider Hollywood ecosystem around it.READ more
26 Nov 2015 // 3:00 AM
All of Harryhausen's invocations of mythical antiquity deserve attention and study, regardless of their fidelity to ancient sources, and despite (or perhaps because of) the rise of 'New Hollywood' and the summer blockbuster.READ more
19 Nov 2015 // 11:04 AM
A classic theme is turned inside out in all the right ways.READ more
26 Oct 2015 // 8:30 AM
The Force is strong in this intricate, and refined narrative.READ more
22 Oct 2015 // 4:12 PM
The Force Awakens -- which arrives 10 years after the last installment in the series -- is the first Star Wars film of the social media age.READ more
15 Oct 2015 // 7:39 AM
- //Multimedia
- //Blogs
- //
Make no mistake: you're not the chosen one, and you're not meant to bring balance to the Force.READ more
2 Oct 2015 // 11:30 AM
The elaborate devotion of Star Wars fans is as well-known as the going-on-40-year-old franchise itself.READ more
1 Oct 2015 // 9:10 AM
What do we mean when we talk about Star Wars now? Do we still mean the movies? Or do we mean the culture that sprouted up around it almost 40 years ago and refuses to go away?READ more
The Wild Things "F.I.A" (video) (premiere) // Music
Last Leaves "The World We Had" (video) (premiere) // Music
Fly By Midnight "2U" (David Guetta cover) (premiere) // Music
A Valley Son "Leaving Is Easy" (audio) (premiere) // Music
The Moving Pixels Podcast Discusses 'Tales from the Borderlands Episode 2'
// Moving Pixels
"Our foray into the adventure-game-style version of the Borderlands continues.READ the article


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Review of interior cabins
Sail Date: November 05, 2015
Reviewed: 1 year ago
Traveled As: Family (young children)
Room Type: Inside
I was somewhat disappointed in the interior cabin for my daughter and son-in-laws cabin. We requested king bed with 2 bunks. It was not declined upon booking, but they had to sleep in twin beds. Protocol wouldn't allow the ladder to be removed and the beds slid together as a king. We know that the rooms are a bit smaller on the inside cabins, but we didn't realize this ship was so much older, the cabins didn't even have a mini fridge. No samples in the bathrooms. The stewards were wonderful as was the rest of the staff, as we have come to expect. Would have liked a little heads up on the cabin situation. We could have upgraded some.
Category Ratings
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|Cabin / Stateroom
|We read about magnets for holding important papers etc. NO LUCK here. Good thing I didn't spend $ on them.
|Children's Programs
|Service and Staff
|Food and Dining
Port Ratings
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We were in a great location.
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Healthy Meals Prepared For Seniors At Home...
Personalized Menus & Affordable Prices!!
Serving Greater Houston including Uptown, Downtown, Midtown, Memorial, River Oaks, Katy, Pearland, West University, Cypress, The Heights, and Sugar Land.
At Amazing Kitchen, we recognize the importance of providing nutritious meals to seniors and that's what we do... We prepare healthy meals for seniors in their home! Personal chefs for seniors? A simply wonderful idea!! How would you like to have someone arrive at your home, with the foods you love and can enjoy, and prepare them personally for you. Well, now you can!! And best yet...chefs can help seniors remain in their homes and age in place!
At Amazing Kitchen we recognize (and are sensitive to) the need of providing nutritious meals to seniors like you, in your home. We make it our top priority to ensure your complete satisfaction. We serve Greater Houston including Uptown, Downtown, Midtown, Memorial, River Oaks, Katy, Pearland, West University, Cypress, The Heights, and Sugarland.
How Amazing Kitchen Chefs Help the Seniors
Our mission is to help our seniors thrive by eating fresh and healthy meals made in their own home.
– At Amazing Kitchen we provide friendly Professional chefs, who come fully vetted and insured
– Chefs
He/She can cook up to a week's worth of food, including setting up and cleaning up
– Nourishment
We will work with you on maintaining a nutritious yet delicious diet
– Consultation
A consultant will join the chef to work on your diet requirements allergies, restrictions, etc..
We Use Only High-Quality Ingredients
Do you ever wonder what they really put in your food behind those closed kitchen doors? Our chefs handpick high quality ingredients and bring them straight to your kitchen so that they are extra fresh.
If you already have existing ingredients that you want to use, just let us know! Our chefs will prepare your meal the way you want it, right in front of you.
We recognize, and are sensitive to, the needs of providing these services to seniors and we make it our top priority to ensure their satisfaction. It can be difficult, and occasionally physically impossible, for some, to go through the steps to shop for, and prepare all of their own meals, and that's where we come in.
How It Works
Book Your Chef – Call or email us and we'll pair you with one of our professional chefs within 48hrs.
About Us
Amazing Kitchen was started by an energetic -and very busy!- woman named Charity in a little apartment in the heart of Houston. Coming home from a tiring work day, she wondered what it would be like to have a private chef cook her dinners for her. After scouring the web, Charity was astounded by the asking prices of hiring a private chef to cook her 7 days worth of meals once a week.
Fueled by the belief that hiring a private chef should be more accessible, she started Amazing Kitchen. Those very beliefs lay the foundation of Amazing Kitchen today – hiring a private chef should be convenient, affordable, and most of all enjoyable!
Contact Us Today!
At Amazing Kitchen, we understand that home is where the heart is, and you don't have to leave home or break the bank for restaurant quality dining. Eating should be enjoyable, hassle-free, and a time to relax. So relax, our chefs have got you covered. For more information, please call (713) 397-1355 or complete our Request for Information Form below.
Kitchen Chefs For Seniors!
Buffalo Speedway #132 | Houston, TX 77025
Tel: (713) 397-1355
Home | About | Advertise | Contact Us | Site Map | Privacy Policy
Elder Options of Texas
Copyright 2001-2017
All Rights Reserved
DISCLAIMER: Links to other websites or references to products, services or publications do not imply the endorsement or approval of such websites, products, services or publications by Elder Options of Texas. The determination of the need for senior care services and the choice of a facility is an extremely important decision. Please make your own independent investigation.


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About Balthali
Balthali Eco Hill Resort
Balthali-5, Nepane
Kavreplanchok, Nepal
Phone: +977-1-6923728
Mobile: +977- 9851168851
Url: www.balthaliresort.com
From US$ 60
per Night
Tents and Fire Place
Hotel Address
Location, Location
Balthali village is famous a soft multi-day hike for the Family, individuals and groups. You could start and end in Kathmandu, meandering past Buddhist temples and rural hamlets. Overall, this is a relaxing area to trek and remains relatively uncrowded compared to more popular routes in Nepal. Lonley Planet the world famous guide book mentioned Balthali as the world's best multi day treks without High altitudes.
Luxury at Hill Top
Our Rooms
We have fixed luxurious tents at resort premise. We have 6 tents which can accommodate for 12 persons. There are 2 single beds on each tents. Toilets and bathrooms at beside of the fixed camp. We also built the BBQ and fire place for the camping lovers. Below are the picture of tent and fire place.
We specialize in making sure our guests are taken care of. From the time you walk in our doors until the time you leave, you'll receive top-notch service. Feel free to eat at our restaurant or contact our concierge for any number of activities that we have going on during your stay. We promise your stay here is like nothing you've ever experienced.
We're sticklers for ensuring your quality stay with us. From memory foam mattresses, the carpeted floors, our rooms are sure to dazzle you.
Copyright © Balthali Eco Hill Resort. All rights reserved.


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It only takes a minute to get started. Fill out our simple sign up form and login to the website.
This step is up to you but will dramatically raise your chances of getting interest from other Christian members on the site. Write a little something about yourself, your hobbies and upload any nice photographs of yourself.
Use our website's advanced search to pinpoint members who suit your criteria. Or just scan through listings of Christian singles and pinpoint singles that arouse your interest.
Identified someone who appeals to you? Send them a message or just a wink and see if anything happens. With a little luck you'll be on your way to finding that special someone for you.
And start dating


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How is pointing out the obvious an agenda?
Being an asshole isn't something to be proud of, btw, but it sounds like you're too far gone ;)
Response to Hollywood's Ill-Timed Woke White Men:
White Savior movies definitely are a problem. It's embarrassing when Hollywood tries to movies like these to show how "progressive" and Totally Not Racist they are. Make a movie with a black hero or where black people save themselves like jfc Super Becky just doesn't cut it, it's corny.
Response to Can You Spot The M&M Among The Skittles?:
5/7 I scared myself how well I did smh
I agree with the message about assisted suicide but I do agree also with the group that they didn't have to portray disability as something you should want to kill yourself over.
My son has a giant omphalocele and required open heart surgery on two holes at 3 months old. People tell me I'm brave; I'm not brave, I'm a mother- it's my son who's brave.
That giving (for me, pegging) is just as fun as receiving. People are to quick to judge something before trying it!!
Response to Have You Ever Stolen Something?:
It actually hurts when I'm stressed out and you joke about me 'being crazy'.
You're only making my anxiety worse, pal.
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'Kick' marks producer Sajid Nadiadwala's debut as a director. "I am ecstatic to be directing Salman Khan, with whom I have shared a very good rapport over the years. Releasing the movie on Eid would be like cherry on the icing, as Salman has already proved his mettle with Eid releases and we hope to recreate the magic with 'Kick'," Sajid said in a statement.
The shooting for the film has begun in Glasgow.


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Bioinformatic pipelines in Python with Leaf
Sequence analysis (applications)
An incremental, loosely planned development approach is often used in bioinformatic studies when dealing with custom data analysis in a rapidly changing environment. Unfortunately, the lack of a rigorous software structuring can undermine the maintainability, communicability and replicability of the process. To ameliorate this problem we propose the Leaf system, the aim of which is to seamlessly introduce the pipeline formality on top of a dynamical development process with minimum overhead for the programmer, thus providing a simple layer of software structuring.
Leaf includes a formal language for the definition of pipelines with code that can be transparently inserted into the user's Python code. Its syntax is designed to visually highlight dependencies in the pipeline structure it defines. While encouraging the developer to think in terms of bioinformatic pipelines, Leaf supports a number of automated features including data and session persistence, consistency checks between steps of the analysis, processing optimization and publication of the analytic protocol in the form of a hypertext.
Leaf offers a powerful balance between plan-driven and change-driven development environments in the design, management and communication of bioinformatic pipelines. Its unique features make it a valuable alternative to other related tools.
Systemic Bioinformatic analysis requires heterogeneously composed research groups, including data producers, data miners and application domain experts (such as biologists). Data producers use dedicated technology on biological specimen to extract data; data miners analyze data and try to highlight relevant information; biologists examine the filtered data, which thy then validate through targeted experiments and use to support their hypothesis or to formulate new ones (See Figure
Figure 1
Example of bioinformatic collaboration
Example of bioinformatic collaboration. Bioinformatic research collaboration scheme. This is a representation of a typical process in a bioinformatic study where different research units are involved. The left part of the scheme represents a loop with iterations that are usually cheaper (no consumables or expensive technologies involved) and more prone to be iterated over time in order to refine the analysis based on partial results. This loop represents a major challenge in terms of code maintainability.
Indeed the priority of custom data analysis software is above all about results, while features like code maintainability, documentation and portability are often considered secondary. In our experience, a precise design of the analysis process is usually impossible to achieve in advance, since the feedback produced by preliminary results may drive the study in unpredictable directions. In fact, the main shortcoming of plan-based development paradigms is in their lack of responsiveness to change. Software Engineering deals with such issue by means of dedicated development models (Extreme Programming, Prototype-based Programming
However, if taken to an extreme, prototype-based approaches tend to undermine the integrity of the system's architecture
In order to take into account the need to reduce planning and at the same time maintain high level structuring in bioinformatic analyses, we developed the
Figure 2
Leaf architecture
Leaf architecture. A Leaf project is carried out by three different layers. On the top layer, a high level definition of a pipeline is coded through the Leaf Graph Language (LGL). The Pyleaf library is able to interpret an LGL graph as a computational pipeline and bind the nodes of the pipeline to the user's Python code.
Figure 3
User interaction
User interaction. The interaction between the user's Python code and the Leaf system happens through the definition of an LGL graph (the high level pipeline) and the use of Pyleaf. The user creates a new Leaf project by providing Pyleaf with the pipeline definition, the Python code implementing each node of the pipeline and the primary resources to work on. The project is then used to request the production of resources.
Figure 4
LGL syntax examples
LGL syntax examples. This figure shows some examples of graph structures defined through the Leaf Graph Language (LGL). Tree structures of any depth and degree can be encoded using the fork arrow (
The formal definition of a pipeline is used by Leaf to provide a number of automated features described in the next sections. As a final output, Leaf is able to generate a hypertext document describing both the high level design and all the details of the analysis (the
Previous work
The development of data flow management systems has recently become a very active area in bioinformatics
In general, the most high-level tools try to encapsulate implementation details as much as possible in order to facilitate interactions with the top layer of the analysis. The user is presented with a Graphical User Interface and builds a bioinformatic pipeline with point-and-click applications. Examples of graphical approaches include Galaxy
A thinner abstraction layer is provided by a number of pipeline design tools based on formal languages, such as Anduril
The thinnest abstraction layers allow the user to easily bypass the pipeline manager itself, if needed. Leaf sits in this category, together with other tools like Ruffus
The major shortcoming of Ruffus has been highlighted in
Figure 5
Comparison between Ruffus and Leaf code
Comparison between Ruffus and Leaf code. Code for pipeline definition and use is highlighted in bold. Both samples implement the same simple pipeline made of three nodes (namely
Like Leaf, Bpipe includes a dedicated language to define pipeline structures. However, Bpipe is primarily intended to be a pipeline-oriented replacement of shell scripts, built to run a pipeline of system commands that exchange data through files on the disk. This approach is the most straightforward, for example, in any environment where nodes of the pipeline are standalone programs. On the contrary, Leaf is meant to provide pipeline management support for general purpose scripting languages, such as Python. Nodes are implemented as functions that can exchange structured variables of arbitrary complexity in primary memory (the use of files is optional). With Leaf (and Ruffus), the definition of such functions can be provided together with the pipeline structure in the same source file.
In this section we introduce the concepts that formalizes the idea of bioinformatic pipeline implemented in Leaf. A Leaf pipeline is designed incrementally throughout the development phase of a bioinformatic analysis. Once the analysis is completed, a final protocol can be generated that documents the analysis process.
Resources and processors
In our view, there are two kinds of actors in a data analysis process: Resources and processors. Resources are any type of data, including raw data, processed data, images, files etc. Here, by "raw data" we mean data at any stage that does not represent a final result of the analysis. Processors are computer routines that can modify existing resources or create new ones.
We subsequently distinguish between
Bioinformatic protocols as annotated DAGs
A graph
We define a bioinformatic protocol as an annotated DAG. Here, annotations are all the details that are necessary to understand and execute the procedure described by the graph, including source code and documentation of the processors and the produced resources. Leaf protocols also include statistics detailing the time and space consumed by the execution of each node. Finally, since the actual implementation of Leaf requires each node to produce only one resource (even though it can be a structured object), the association of resources with edges is equivalent to the association of resources with nodes.
Leaf is a software tool that supports the generation and use of bioinformatic pipelines as defined in the previous section. The Leaf system is composed of two subsystems (see Figure
Figure 6
Source code embedded pipeline definition
Source code embedded pipeline definition. Any programming language supporting multi-line text can include the definition of a pipeline as LGL code. Left: a Python example including an LGL graph definition whose nodes are implemented in the same source file. Right: a graphic representation of the corresponding pipeline.
Figure 7
Coexistence of leaf and python
Coexistence of leaf and python. (A) Python source code including a pipeline definition as an LGL graph (Section "Concepts" in the source code), the implementation of the corresponding nodes and a function creating and returning a Leaf project object accordingly. (B) Example of a Python interactive session where the user loads the previous Python code, creates the Leaf project and request the production of a resource. The user can directly call pipeline nodes as regular Python functions by passing the input parameters manually. Leaf can call them automatically for the production of a resource as necessary. The thinness of the Pyleaf library abstraction layer allows for quick prototyping and experimentation.
The LGL compiler (lglc) was built using the
Graph visualizations are produced using
The leaf graph language
The Leaf Graph Language (LGL) is a formal language with the unique feature of having a graphical appearance even though it is written in regular text. The purpose of LGL is to encode general graph structures (including graphs containing cycles, which are not supported by Pyleaf). An LGL graph definition can be directly embedded in the code of other programming languages to serve as a high level pipeline description. While a formal description of the language's grammar is beyond the scope of this paper, in this subsection we present a few examples as well as the main syntax rules in order to illustrate its basic philosophy.
The fundamental objects in LGL are items, item sets, and arrows connecting items or item sets. Each item may represent a graph node or an entire graph by itself, while an arrow may represent a single edge or a set of edges. For example, the statement:
is an LGL instruction that creates a graph with three nodes,
which defines the set of edges {(
An item can represent a complex object when using named graphs. A named graph is a graph preceded by a text label and a colon, like in the following statement:
After the definition of a named graph, its label (
creates three graph objects: the named graph
creates a single graph
The mechanisms described above are sufficient to describe any graph in LGL. However, another syntax construct, the fork arrow, is introduced to improve readability. The fork arrow allows the user to define a tree structure that is visually evident. The
The fork operator is composed of the
Any fork can indeed be redefined as an arrow. Finally, special flags can be associated with nodes by enclosing them in square brackets, as in the following example:
This instruction creates the graph
Pyleaf is a Python library that is able to bind the node names of an LGL graph to Python functions in order to interpret it as an analysis pipeline. As previously mentioned, the semantics of the graph see nodes as processors and edges as input/output connections between them. Root nodes are meant to be associated with primary resources, terminal nodes with final resources, and other nodes with raw resources. With Pyleaf the user can request the production of a resource by identifying it directly with the name of the processor producing it.
For Pyleaf to work two objects are needed: the pipeline structure in the form of a multi-line Python string containing a graph in LGL code; and the name of the Python source code file where the functions implementing the pipeline nodes are defined. Indeed, the binding between the nodes and the corresponding Python functions is performed by searching for LGL nodes and Python functions having the same name. With this information Pyleaf can build a
In order to create the object
The interaction between functions bound to pipeline nodes happens as follows. Each function has only one output resource, though it can be an arbitrarily structured object, as usual in programming languages. If a node in the pipeline has more than one outgoing edge, it will provide the same resource along each edge. On the other hand, a node having
When the user requests a resource, Pyleaf is able to identify the part of the pipeline that needs to be executed in order to build the resource. A sequence of function calls is thus performed according to the pipeline structure, where the output of each node forwarded to all of its descendants, according to the rules explained above. In order to optimize pipeline execution, Pyleaf supports parallel processing of independent nodes and mechanisms for "lazy processing", which means it doesn't execute processors that are not required to satisfy a user request. When referring to "unnecessary nodes" we mean nodes that are not in the path between a primary resource and the requested resource, as well as nodes that are in said path but whose output has been previously computed (and whose source code has not changed since then). This is possible because Pyleaf automatically stores all derived resources in primary and permanent memory as soon as they are produced. As an example, let us suppose that a user requests the production of the resource that is produced by the processor
Pyleaf will refer to the protocol's graph and run the
As mentioned, Pyleaf also supports parallel computing by exploiting multicore machines. For example, if the execution of the entire pipeline is requested (using the
Pyleaf also maintains a database that stores the source code of all the processors in order to ensure consistency between the current state of the pipeline and the produced resources. If a processor is modified, all dependant resources are automatically cleared (unless the user explicitly requests to
Finally, Pyleaf can automatically export the entire analysis as a hypertext document implementing our concept of bioinformatic protocol. The document includes a visualization of the pipeline, with nodes containing hypertext links to processor details. Such details include processor source code, documentation (automatically extracted from the original source code), execution time, and hypertext links to produced files together with their size. Overall time and space consumption as well as other statistics for the pipeline as a whole are also included. See Table
Leaf and Python frameworks coexistence
The Leaf system is completely transparent to the user's development environment. The LGL graph is defined as a multi-line Python string in the same source code implementing the Python functions that carry out each step of the analysis (see Figure
A common practice when extending an existing analysis within the Leaf environment is to exploit the protocol in order to easily set up the starting point for a new branch in the pipeline. Then the user requests to Pyleaf the resources that are necessary to the new branch. Pyleaf loads them from the disk or builds them on the fly running the necessary nodes from the pipeline and returns them to the user as regular Python objects. The user is able to define and test a new Python function and finally add it as a new node to the LGL graph in order to make it part of the pipeline. Conversely, existing pipeline nodes can be tested with new inputs by calling them as regular Python functions in a shell environment. In Leaf the usual direct call of Python functions seamlessly coexists with their indirect use as pipeline nodes.
Application example
The Leaf system was developed to overcome practical problems that arose during a bioinformatic research project, the results of which are to be published soon. This application example included three main collaborating research units: application domain experts, data producers and data analysts (see Figure
The project involved a copy number variation (CNV
Figure 8
LGL code for the CNV project
LGL code for the CNV project. The computational protocol in LGL for a real Copy Number Variation study. Compare with Figure
Figure 9
Protocol's graph for the CNV project
Protocol's graph for the CNV project. Graphical representation of the LGL code of Figure
The LGL code in the example (Figure
A slightly more complex LGL statement defining the same structure could be:
where line breaks and indentation are discretionary. Since complex structures can be difficult to code, LGL provides simpler alternatives. The choice of syntax complexity level is left up to the programmer based on his skill level and preference.
The generated protocol for the latest version of the CNV project pipeline is available at the Leaf home page
A balance between agility of code development and overall consistency and communicability in rapidly changing environments such as interdisciplinary research collaborations, is of fundamental importance, in regard to both methodology and efficiency. High-level tools are the most efficient when working on the general structure of the analysis, but make low-level interventions difficult. On the other hand, the use of formal design approaches can improve the robustness of a bioinformatic analysis, but at the cost of reducing responsiveness to change.
The Leaf system, like other tools in the same category, allows for low-level access to implementation details, but still provides tools for the management of a light-weight, loosely structured data flow layer. In particular Leaf supports a dedicated pipeline definition language, LGL, whose flexible coding style allows the programmer to choose his preferred balance between easy to read and easy to write code.
To our knowledge, Leaf is the only pipeline manager that allows the definition of both the pipeline and its nodes in the same source file, while at the same time keeping them separated. Besides the general properties connected with the design of the Leaf system, we also highlighted some features supported by the Python implementation of Leaf that are not present in similar tools, such as the monitoring of source code, which allows for consistency checks between code and resources. Additional features already present in other tools have been further developed in Leaf, such as the generation of pipeline documentation in the form of a hypertext, including links to the files produced during pipeline execution and statistics about time and space requirements detailed for each node, to name a few.
In our opinion, both the design philosophy and the implemented features of Leaf make it a valuable alternative to other pipeline management systems.
Availability and requirements
Project name: Leaf
Project home page:
Operating system(s): Linux, Windows. Mac OS under development.
Programming language(s): C++, Python.
Other requirements: Python ≥ 2.6.
License: MIT.
Any restrictions to use by non-academics: None.
LGL: Leaf graph language; DAG: Directed acyclic graph.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
FN designed and implemented the Leaf system. RT provided design and implementation feedback. RMC provided application domain feedback. RT and RMC supervised the project. All authors contributed in writing the manuscript and read and approved the final version.
The work was funded by the Italian Association for Cancer Research (AIRC, Milan, Italy, IG 9168 to R. Mariani-Costantini). The authors would like to thank Donatella Granata and Ellen Abrams for their useful comments on the manuscript.
Advances in dataflow programming languages
Python: a programming language for software integration and development
A comparison of common programming languages used in bioinformatics
Dynamically typed languages
Agile software development, the people factor
Provenance and scientific workflows: challenges and opportunities
Provenance as dependency analysis
Why and Where: A Characterization of Data Provenance
The case for open computer programs
Leaf Home Page
Leaf source code repository
Biopython: freely available Python tools for computational molecular biology and bioinformatics
Automation of in-silico data analysis processes through workflow management systems
Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
Taverna: a tool for building and running workflows of services
Pegasys: software for executing and integrating analyses of biological sequences
Conveyor: a workflow engine for bioinformatic analyses
Kepler: an extensible system for design and execution of scientific workflows
Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme
Biopipe: a flexible framework for protocol-based Bioinformatics analysis
Ruffus: a lightweight Python library for computational pipelines
Bpipe : a tool for running and managing Bioinformatics pipelines
flex: The Fast Lexical Analyzer
Bison - GNU parser generator
Graphviz - Graph Visualization Software
Mechanisms of change in gene copy number
PennCNV: An integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data
A simple and efficient access to R from Python


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Worried of a new type of "digital divide," David Blumenthal, M.D., National Coordinator for Health Information Technology, is calling on electronic health records vendors to ensure their sales and marketing activities include providers serving minority communities.
In his latest blog entry, Blumenthal and Garth Graham, M.D., HHS deputy assistant secretary for minority health, note low EHR adoption rates among providers serving Hispanic or Latino patients who are uninsured or covered under Medicaid. "More over, this data also identifies that EHR adoption rates among providers of uninsured non-Hispanic Black patients are lower than for providers of privately insured non-Hispanic White patients," they say.
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Porsche Design P'135 Titanium Pen Is The Ultimate Writing Gift
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Navico acquires mapping and software development company
by Sam Brown on 28 Jan 2014
LakeTrax™ powers Navico's revolutionary Insight Genesis™ global map-making tool. . ..
Navico Holding AS, parent company to the Lowrance, Simrad and B&G brands, announced today that it has acquired Contour Innovations.
Contour Innovations is a mapping and geospatial software company that created the LakeTraxTM platform, which powers Navico's revolutionary Insight GenesisTM global map-making tool. Navico has worked closely with the Contour Innovations team for the past two years to bring Insight Genesis to market. To date, Insight Genesis has provided innovative map-making tools to 146 countries – a number that continues to grow with each passing month.
Contour Innovations is also the creator of the innovative BioBase software and service, which allows aquatic biologists, government agencies, researchers, and others to implement long-term monitoring programs related to current and historical aquatic vegetation densities and other water-quality characteristics. Navico will add BioBase to its diverse product portfolio and introduce its advanced functionality into new and emerging markets.
'Mapping content is a strategic priority for Navico's growth ambitions,' said Leif Ottosson, president and CEO of Navico Holding AS. 'With the acquisition of Contour Innovations, and its talented team, we will rapidly strengthen and expand the functionality of our Insight Genesis service. We are confident that accelerating and adding even more innovative capabilities to Insight Genesis will be a big win for our customers.'
'Closer integration through this acquisition will allow us to speed and enhance the delivery of software features and new solutions for existing and future customers', said Matt Johnson, CEO of Contour Innovations, LLC. 'The entire Contour Innovations team is excited to join the Navico family and looks forward to elevating our mapping and software solutions to exciting new levels.'
The acquisition of Contour Innovations is the second purchase Navico has announced in the last six months. The company recently acquired Consilium's radar business to add top quality radar products and competencies to its Simrad Professional range of products. With the acquisition of Contour Innovations, Navico will retain its talented team, including technical development experts, aquatic biologists and avid outdoors enthusiasts.
For more information on Navico, please visit www.navico.com. For more information on Contour Innovations, visit www.contourinnovations.com.
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Prix pour vente rapide !
- Year:
- 2008
- Length:
- 32'
- Engine/Fuel Type:
- Single / diesel
- Located In:
- Marines de Cogolin, France
- Hull Material:
- Fiberglass
- 74421-3019922
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Unité de 2008 , jamais loué , bien équipé ,possibilité de place de port . Vente urgente , faire offre .
FOR MORE INFORMATION PLEASE CONTACT ALEXIS MARTIN email@example.com 00 33 (0)6 07 46 20 33
Please contact Alexis Martin at 00 33 (0)6 07 46 20 33
Additional Specs, Equipment and Information:
Builder: Dufour Yachts
Designer: Umberto Felci
Keel: Other
Hull Shape: Monohull
LOA: 9.80 m
Beam: 3.40 m
LWL: 9.27 m
Minimum Draft: 1.85 m
Dry Weight: 4699 kgs
Total Power: 19 HP
Engine 1:
Engine Brand: Volvo
Year Built: 2008
Engine Model: D1-20
Engine Type: Inboard
Engine/Fuel Type: Diesel
Propeller: 2 blade propeller
Drive Type: Sail drive
Engine Power: 19 HP
Fresh Water Tanks: (158 Liters)
Fuel Tanks: (90 Liters)
Number of single berths: 2
Number of double berths: 2
Number of cabins: 2
Number of heads: 1
Number of bathrooms: 1
Navigation center
Wind speed and direction
Cockpit speakers
CD player
Furling genoa
Battened mainsail
Steering wheel
Inside Equipment
Hot water
Electric bilge pump
Marine head
Battery charger
Manual bilge pump
Electrical Equipment
Shore power inlet
Electrical Circuit: 12V
Outside Equipment/Extras
Cockpit table
Outboard engine brackets
Swimming ladder
Cockpit shower
Total Liferaft Capacity: 6
Electric windlass
Bimini Top
Lazy bag
Spray hood
Additional Description
- Teak trimmed seats, GRP sole.
- Large side locker with lid fitted with padlock hasps.
- Rudder stock head under helmsman's sole for installing the emergency tiller.
- Engine lever and control panel easily available to the helmsman.
- Transom open in centre by removing helmsman's seat giving access to the swimming/boarding platform.
- Gas cylinder locker in aft port seat.
- Life raft stowage in starboard cockpit locker.
- Cockpit shower in aft locker.
- Folding bathing ladder.
Additional Description
- All joinery work is in prime Moabi mahogany, with fiddles, mouldings and framings in solid wood.
- All Cabin doors have a blocking system which keeps doors open where required.
- Soles are in Moabi laminated floor boards.
- Saloon cushions and cabin mattresses have removable covers.
- The upper cabin linings are in Moabi wood, the bottom in cream vinyl.
Additional Description
- 12 V DC system.
- Switchboard with circuit breakers, voltmeter, 12V outlet.
- 1 x 60 Ah engine battery.
- 1 x 60 Ah house battery.
- Battery switch for each circuit.
Additional Description
- L-shaped galley with a large worktop in synthetic stone.
- Stainless steel sink.
- Chrome plated brass mixer tap for pressurised water.
- Cooker with a two burner stove with oven on gimbals.
- 12V refrigerator unit with minimum capacity 120 litres, stowage box, and separation.
- Crumb tray under sole.
Additional Description
- VOLVO 19 hp (13.8 KW).
- Sail-drive transmission.
- Heat exchanger, anti-siphon valve.
- Control panel close to helmsman,
- Approximately 90 litre fuel tank with a gauge on the electrical switchboard.
- Fuel filter with water separator.
- Emergency fuel shut-off handle.
- Engine room ventilation blower, and two ventilation hoses.
- Two-blade fixed propeller.
- Multiple access to the engine. Independent engine bilge.
- Quality sound proofing with high idensity foam.
Additional Description
- Teak handrails on coachroof. Teak toerail.
- Self-draining chain locker with eye bolt and integrated windlass bracket, lid with locking bolt.
- Stemhead fitting anchor roller.
- Pulpit with wooden step and separate port/startboard navigation lights.
- Pushpits with horseshoe buoy bracket, flag pole holder, navigation lights, and opening cable gate with hook.
- Stanchions with two levels of life line.
- Four aluminium mooring cleats.
- Single stainless steel chainplate for cap shrouds/aft lower shrouds.
- Two chainplates for backstay.
- Two deck fillers, one for water and one for fuel.
- Mainsheet tackle on the roof.
- Boomvang with 4:1 purchase.
- Genoa sheet tracks with piston lead blocks.
- Genoa sheet turning blocks on coaming.
- One x four sheave deck organizer for halyard returns, mainsail sheet and reefing lines.
- Stainless steel swan neck electric/electronic cable gland.
- Four clutches on roof.
- One x 32.2 ST halyard winch on roof.
- Two x 32.2 ST Genoa winches on coamings close to the helmsman.
- 2 winch handles with holder.
- Owner's briefcase with owner's manual.
Rigging and Sails
- Anodised aluminium mast with double swept backed spreaders, rigged 9/10, deck stepped.
- Anchor and steaming lights.
- Boom topping lift cleat.
- Anodised aluminium boom equipped with a two single line reefing system.
- Genoa furler.
- Grounded rigging system.
- Continuous standing rigging in single strand stainless steel cable and chrome plated bronze turnbuckles including: Forestay, double backstay, cap shrouds, inter and lower shrouds
- Pre-stretched running rigging including: Main and Genoa halyards, boom topping lift, Main and Genoa sheets, two reefing lines, outhaul line, furling line, boom vang tackle.
- Mainsail equipped with two broad reef bands, with battens and bag.
- Furling Genoa with anti- UV protection.
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The Great Learning is the first of the Four books which were selected by Zhu Xi during the Song Dynasty as a foundational introduction to Confucianism. It was originally one chapter in Classic of Rites. The book consists of a short main text, attributed to Confucius, and nine commentaries chapters by Zeng Zi, one of Confucius' disciples. Its importance is illustrated by Zeng Zi's foreword that this is the gateway of learning. Some of the terms within the text form an important part of both classical and modern Chinese political discourse. For example, the concept of world peace has been the stated goal of Chinese statecraft from the Zhou dynasty to the Kuomintang to the Communist Party of China. Another term used in the text qin-min which Legge translates as renovating the people is the name of the People First Party, one of the minor parties in Taiwan. The Great Learning is significant because it expresses many themes of Chinese philosophy and political thinking, and has therefore been extremely influential both in classical and modern Chinese thought. Government, self cultivation and investigation of things are linked. It links together individual action in the form of self-cultivation with higher goals such as ultimate world peace as well as linking together the spiritual and the material. By defining the path of learning (tao) in governmental and social terms, the Great Learning both links the spiritual with the practical, and creates a vision of tao that is radically different than that presented by Taoism. In particular, the Great Learning sets Confucianism as being this-worldly rather than other-worldly. Instead of basing its authority on an external deity, the Great Learning bases its authority on the practices of ancient kings. The text also sets up a number of controversies that have underlain Chinese philosophy and political thinking. For example, one major controversy has been to define exactly the investigation of things. What things are to be investigated and how has been one of the crucial issues of Chinese philosophy.
Detalhes do Produto
- Formato: ePub
- Origem: IMPORTADO
- Editora: START PUBLISHING LLC
- Assunto: Filosofia
- Idioma: INGLÊS
- Ano de Edição: 2013
- Ano: 2013
- País de Produção: Canada
- Código de Barras: 2001047299103


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Title: Once Delivered to the Saints: An Orthodox ...
Publisher: St. Nectarios Press: Seattle
Publication Date: 2000
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1st edition, 1st printing so stated. Large paperback in tan pictorial wraps with red and black lettering. Unmarked, sharp corners, clean text block. PON in a neat hand on ffep. 356 pp. A fine copy in every way of this now scarce masterpiece of Greek orthodox theology. Fine. Bookseller Inventory # 330
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