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program director jobs near Milford, DE
Refine your searchClear Filters
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Clinical Director
Compassionate Care Hospice - Georgetown, DE
To run our Georgetown program. We are actively seeking a *Clinical Director*. The Clinical Director acts as an intricate part of our interdisciplinary team with...
Business Performance Management/Service Line Business Coordinator (FT)
Beebe Healthcare - Lewes, DE
Evaluation of SL and program opportunities, including business plans and ROI's. Provide analytical, financial and strategic reporting support to our Executive...
Director IT Infrastructure and Operations
Dover area - Dover, DE
Provide direction and resources to Projects and Programs for infrastructure components. The IT Infrastructure and Operations Director plans, directs and...
RN - Clinical Educator/ ICU (FT)
Beebe Healthcare - Lewes, DE
Previous experience with coordinating and presenting educational programs preferred. Demonstrates leadership in the development of education programs and...
Director of Nursing (DON)
Harbor Healthcare and Rehabilitation - Lewes, DE
Is seeking a *FULL TIME Director of Nursing (DON)*. Qualified canddiates may apply with resume and letter of interest, or call *(302) 645-4664*....
US-Associate, Executive, and Senior Director
Community Counselling Service Co., LLC - United States
CCS offers competitive benefits, a dynamic training program, resources, career advancement, mentoring, and networking opportunities....
Revenue Cycle Manager
Choptank Community Health System, Inc. - Denton, MD
Rick Barton, HR Director. Experience with coding, billing, charge entry, adjustments, reimbursements, and sliding fee programs....
Emergency Room Nurse
U.S. Army - United States
PARTNERSHIP FOR YOUTH SUCCESS (PaYS) Program. Nurse Loan Repayment Program of up to $120,000 over three years;...
Nurse Anesthetist
U.S. Army - United States
Program director or deputy program director; Phase II director; Healthcare Professionals Loan Repayment Program. PARTNERSHIP FOR YOUTH SUCCESS (PaYS) Program....
On-Campus Internship
The National Society of Leadership and Success - United States
Participate in weekly coaching sessions with a Student Program Director. Research the Society and its leadership program....

subset: commoncrawl


text:
February 27, 1989
What does oil shale's past mean for its future?
... to read the essays, news stories and other articles in the issue, including the sampling below
Unocal did not leave with the rest of the shale crowd in 1982. But all isn't well with the nation's first and only commercial-scale oil shale plant.
The West's immense deposits of oil shale are estimated to hold more than 1.8 trillion barrels of oil, but so far they have proven far more valuable to lawyers and land speculators than to oil men.
Writer Wallace Stegner has a rule of thumb: The more arid a state, the worse its congressional delegation. I have a corollary to that rule: The more a state is "blessed" with natural resources, tile worse off it will be economically, socially and politically.
- After attack, the country's oldest park ranger is back at work
- Arizona Sen. Jeff Flake's criticism of Trump wins him national prominence
- Emotions run high over monument designation in Utah
- BLM moves away from landmark Northwest Forest Plan
- How Utah coal interests helped push a secret plan to export coal from California
- Steve Snyder on What can we still learn from Edward Abbey, 25 years after his death?
- David W Hamilton on We should be proud of delisting grizzlies
- David W Hamilton on Sometimes, the West must be protected from itself
- Brant Hayenga on BLM moves away from landmark Northwest Forest Plan
- David W Hamilton on What can we still learn from Edward Abbey, 25 years after his death?


text:
The MPEG Industry Forum (MPEGIF) will conduct its "Advanced Video Services in Next-Generation Video Ecosystems" full-day master class April 15 at NAB2007.
The class will explore how new technologies are changing the way digital multimedia is created, compressed, delivered and monetized.
Featured keynote speakers include senior executives from Alcatel-Lucent, MobiTV, Telekom Austria and Professor Tim Wu from Columbia Law School, best known for popularizing the concept of network neutrality.
Each session will include an interactive roundtable panel with the keynote speaker and other panelists. MPEGIF will also provide an update of the forum's work in developing and promoting open MPEG standards and the MPEGIF Logo Qualification Program.
For more information, visit www.mpegif.org and www.nabshow.com.
Hawk Loving KOLN Lincoln, Neb. Weathercam
Roberts: 'OTT Economics Are Unproven to Us'
Robert Gessner Re-Elected ACA Chair
NBC's Retrans Haul Could Get Fatter
Gessner Re-Elected ACA Chair
Roberts: 'OTT Economics Are Unproven To Us'
The future of sport
Sky seals Chinese Super League rights
Riedel joins AIMS
Video Artist Bill Viola Adds a Permanent Piece Depicting Mary in St. Paul's Cathedral
Watch the First Trailer for 'Sherlock' Season 4
Steven Holleran Captures Youth and Discontent in 'The Land '


text:
The average salary of a(n) Nurse Registered in Anderson, Indiana is $71,235.
The average hourly rate of a(n) Nurse Registered in Anderson, Indiana is $34.25.
The average bonus of a(n) Nurse Registered in Anderson, Indiana is $1,168.00.
Community Health Network
Current Indiana Registered Nurse license required. This position is located in Anderson ....View job on Indeed.com
Envision Healthcare
RN / REGISTERED NURSE / HOME HEALTH CARE. Current, unencumbered State License as a Registered Nurse (RN). Two years of experience as a Registered Nurse (RN) in...View job on Indeed.com
Cardon & Associates
CarDon & Associates is now seeking LICENSED PRACTICAL NURSES and REGISTERED NURSES. Has an active, in good standing, Indiana license as a Licensed Practical...View job on Indeed.com
Community Health Network
RN, registered nurse, endoscopy, GI. The Registered Nurse Endoscopy position is located in Anderson, IN. Must have a current and valid license as a Registered...View job on Indeed.com
Corizon Health
Licensed as a Registered Nurse in the state of employment. Pendleton Correctional Facility in Pendleton, IN offers FT and PRN Registered Nurses unique...View job on Indeed.com


text:
Winston W. West
The market is "on fire" in Tampa Bay and as an example I listed a property on Monday and within 24 hours had multiple offers from ALL CASH investors above market value.
So if you need to obtain a mortgage you will be at a severe disadvantage because the house must appraise for the purchase price and the investors are bidding up virtually every property that makes sense as a rental property.
Even if you limit your search to properties only available to Owner-Occupant Buyers you will still be competing with at least 10 maybe as many as 20 other buyers within 48 hours of listing--unless you're planning to buy above $250k then you may have slightly less competition.
So you need an agile Realtor at your side that is able to show you the first day on the market so you do not miss out. Also be prepared and get a HomePath Mortgage preapproval letter if you're willing to pay "above" market value--you see a HomePath mortgage doesn't require an appraisal. Also HomePath is only available on Fannie Mae owned listing: http://www.HomePath.com
If you want to search "like a Realtor" and see the "real" availability of properties (active with contract are not available to actually buy) you're welcome to sign up for a free Listingbook account on my website: http://www.SoldOnTampa.com
All the best,
Alma Rose Kee, PA
Future Home Realty
It can be crazy to have all pieces of information and try to put it together yourself without any guidance. We can take the time to sit down with you and educate you in a simplified manner so that you can make the best decision for your family. We will also educate you about any down payment assistance programs that work directly with specific lenders. This will be important consultation for you guys so that you may enter the home search in a well prepared manner.
Once we are in agreement and have piece of mind of obtaining pre-approval, we can do the fun part of looking for the perfect home. Call us and let us know if we can be of some help.
Our team would be glad to assist you. First what we need in order to set up a custom home search for you is to know the following:
1. Price Range
2. # Bedrooms and Bathrooms Preferred
3. Desired Living Space Square Footage
4. Do you have a pet or pets? Some associations restrict type and number of pets allowed so it will be important to know what type and size of pets you have.
The great thing about the MLXChange MLS system that our office uses is that our team is able to set up custom home searches that search a specific radius for homes that meet your criteria. Then we can either email you a link to access your own client website that you manage and can mark your favorites or set up your own custom searches. Or, if you prefer, we can just send you a link to view a particular home or a group of homes that meet your criteria. In addition, we can set you up to receive automatic email notifications when new homes become available.
And if you are planning on getting a mortgage and are not already set on who you will use for financing, I can help direct you to some great mortgage pros that our customers have used over the years.
Just email me the above information including your email and we can get started finding a great home at a great value for you.
Fred Strickroot
Lic. FL Real Estate Brokerage
I graduated from USF and my office is also located in the USF area. Feel free to call me or email me and I will do my best to help you with this process.
All the best,
Majid (Jay) Mirzai
Coldwell Banker Residential Real Estate
(904) 501-8698
I work with 1st time homebuyers all the time and would be happy to assist you in the home qualifying and purchasing process. Feel free to contact me anytime. I look forward to hearing from you soon!
Jenn Cook
Bahia Realty Group
Mortgage Broker Responding.
I'm from the Tampa Bay area orginally and unlike a realtor who may promote the area they sell in, I can I give you advice about any area.
In addition, I likely have the most financing options to offer. After reviewing these programs #4 and #5 below, please call me to go over loan options as well as the different areas in Tampa.
1) 100% LTV- VA - pay off debt at closing on a purchases too!
2) 100% LTV- USDA - 12 mo. into Chapter 13 BK…OK Too!
4) 97% LTV- NEW- No monthy MI or FHA 1.75% MIP Fee!
5) 95% LTV- NEW-No PMI!
6) 95% LTV- NEW-CONDO Loan
7) 90% LTV- NEW-No PMI -2nd Home
8) 90% LTV- New-Jumbo w/cc
9) 85% LTV- NEW- No PMI to Super Jumbo
10) 80% LTV- Rental Property
------------STATED INCOME ALT Loan programs-------------
11) 80% LTV- to Super Jumbo
12) 80% LTV- FIX n' FLIP Invest. Prop. – No min. credit!
13) 75% LTV-to Mega Jumbo
14) 75% LTV- Foreign Nationals-to Super Jumbo
15) 75% CLTV-after Short Sale, BK, Foreclosure to Super Jumbo
16) 70% LTV- Hard Money to Jumbo
17) Lot Loans / Land Loans Too!
Go to: http://WWW.PRO-OPTION-COM or call 888-662-4404
Steve McRory
Pro Option Mortgage/ Florida
Ph: 888 662 4404
Prior Service U.S. Marine Corps
The first thing is to get pre-approved by a lender to make sure that you will be ready with the required down payment and pre-approval. Once you find a home, in order to be able to submit an offer, a buyer has to provide a pre-approval or verification of funds is the purchase is cash.
This is a lender I recommend because of his 30 years plus experience.
Rob Pinion
Branch Manager
Office: 813-739-5337
You can view my client recommendations at http://www.trulia.com/voices/profile/Real_Estate_Pro-Tampa_F
I have a few areas in mind. Please call me (813) 679-5307.
Good luck in your search, it is an amazing time to buy!
You need a Realtor to help. I have worked with many first time buyers and can help you through this exciting experience. Please review my profile on trulia and send me a message. Or call me directly at 813-352-6219. I can help you find a lender and answer your questions.
No pressure, just help.
Tracy Hoyt
Prudential Tropical Realty
I will be happy to help you. I live in South Tampa as well and went to USF. I do specialize in first time home buyers. Please call me at 813-624-3679 and I will be happy to help you through the entire process step by step.
Ken Allen
The Toni Everett Company


text:
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Luxurious Alpha tiny house opens wide on both sides to let the outdoors in
This ingenious design features a roll-up garage door and a drop-down deck on either side, allowing the home to feel even more spacious.
Latest Stories in Design - Page 16
Designer transforms ailing tree into striking table
A collaboration with local craftspeople creates this table that looks like it's growing out of a tree stump.
Low-cost Rural Studio homes aspire to be built for $20,000
These homes' innovative design hopes to disrupt how housing is done -- from building techniques, to restrictive zoning and oversized mortgages.
Kengo Kuma's "Nest We Grow" wins Wood Design Award
Deservedly so, we might add.
These recycled 'pasture' rugs bring nature's textures into the home
These unique, handcrafted rugs are made to emulate the look and feel of moss, grass, snow and sand, for enjoyment at home.
Off-grid tiny dwelling is inspired by boat design
An ex-boat builder and carpenter creates this gorgeous little home in New Zealand.
Atlas tiny house comes with its own fold-down patio bar
This small dwelling features a clever fold-down patio deck and ceiling-to-floor windows to bring in lots of light.
All about eaves
Why are architects eschewing overhangs? Because they can.
Underground slurry pit converted into hidden cinema in 258 sq. ft. Parisian studio
An decrepit, abandoned space is revived into an open, spacious studio with its own secret underground room.
Buildings can be boxy but beautiful if you have a good eye
And GO Logic shows again that they really do with the Little House on the Ferry.
Friendly streets: Study shows pedestrians feel safer with white streetlights
Possibly because they make identifying human faces easier.
Flying saucer lands in space ship in latest Apple headquarters drone video
Duncan Sinfield's latest video shows remarkable progress
Watch Buster Keaton build a kit house in his first solo movie
It looks more like Daniel Libeskind than Sears Robuck.
City of Fresno legalizes tiny homes, and Steven M. Johnson is on it
Our favorite cartoonist solves a major problem with tiny houses.
Smart Dutch underpass design accommodates both pedestrians & cyclists
Here's a great example of how to encourage a walkable, bike-able city: build infrastructure that caters to both.
Small 323 sq. ft. apartment is stylishly redesigned for travelers
A tiny apartment in a new tourist hotspot is remade with clever modern elements to maximize space.
Wood-Skin: Composite material that's strong like wood, flexible like fabric (Video)
This digitally fabricated material takes the best of traditional materials and uses new tech to create something unexpected and versatile.
Casa Luca: A new passive house in Vancouver
Architect Lucio Picciano builds a house for his family
This is not a tiny house: Family takes over entire 60s vintage school
And if you like it, you can rent a classroom.


text:
St Clair County News
Local, regional, and statewide news continually updated from thousands of sources on the web.
Breastfeeding in public?
35 Shocking Photos Of What Once-Hot Rock and Pop Goddes...
St Clair County news is powered by NewsRank™
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Updated: Thu Jul 28, 2016 01:06 pm
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This profile was last updated on . and contains contributions from the Zoominfo Community.
Is this you? Claim your profile.
Managing Partner Accenture Strategy
Accenture LTD
Direct Phone: +34 *********
Email: m***@***.com
1345 Avenue Of The Americas 6Th Floor
New York, New York 10105
United States
Accenture is a global management consulting, technology services, and outsourcing company, with more than 358,000 people serving clients in more than 120 countries. Accenture collaborates with clients to help them become high-performance businesses and go... more
Karen Labin
Naples Community Hospital
Ruben Labin
GOF Conference
Claudia Labin
Indiana Writers Center
Zach Labin
West Virginia FILMmakers Festival
Thomas Labin
Marilla Fire Company


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Showing 297 Results for korn
Korn Concert In Missoula
This. Is. Gonna'. Rock.
So hard.
Korn's Jonathan Davis Curses 'No Cussing' Sign at Concert
Korn's Jonathan Davis has still got the life in him! During the band's April 29 set at Rockville 2012 in Jacksonville, Fla., the singer took offense to those who "take offense."
Brian 'Head' Welch Would Reunite With Korn for a Rock Hall of Fame Performance
We recently had the opportunity to chat with former Korn guitarist and current Love & Death frontman, Brian "Head" Welch, and touched upon a wide range of topics. One of them happened to be the recent Guns N' Roses drama at the Rock and Roll Hall of Fame induction ceremony, in which Axl Rose decided not to join his former bandmates at the event.
Korn Win 'Album of the Year' at 2012 Revolver Golden Gods Awards
Korn Singer Jonathan Davis Explains Album Title 'The Path of Totality'
In a new video, Korn vocalist Jonathan Davis explains the significance behind the name of their latest album, the dubstep-infused 'The Path of Totality.'
Korn, Trivium + New Pantera Music Video Added to 2012 Revolver Golden Gods Lineup
The Revolver Golden God Awards have just announced a new batch of rockers to appear at the 2012 ceremony. Not only will Korn, Tenacious D, Dee Snider and Trivium present and perform in the show, but drummer Vinnie Paul will debut a never-before seen Pantera music video from the 'Vulgar Display of Power' recordings.
Korn's Jonathan Davis to Release Electronic EP as Alter-Ego 'J Devil'
It's no secret that Korn frontman Jonathan Davis has an affinity with electronic music. Korn's latest record 'The Path of Totality' delved into dubstep territory and took the band into a new stage in their career. Nowm Davis will soon be releasing an electronic EP under the name J Devil.
Korn Bring the Noise to 'Jimmy Kimmel Live!'
If you missed the live performance from Korn on Kimmel a few weeks ago. Check this out via Loudwire.com.
When it comes to late-night talk shows, it seems like 'Jimmy Kimmel Live!' is the program to catch great acts performing. From Megadeth to Slipknot to Judas Priest, the 'Kimmel' show has had some major talent on its stage. Last night, Korn performed 'Narcissistic Cannibal' and 'Get Up!' on 'Jimmy Kimmel Live!'
Angel's Rock Report–Korn, Trent Reznor, Andy Dick [AUDIO]
Korn will be back out on the road next month. The brief tour starts February 23rd in Detroit. J Devil will open up the show, that would be Jonathan Davis debuting his new DJ set...
Korn Is Looking For A DJ
As we have all heard recently, Korn is trying something new with their new album "The Path Of Totality". They are teaming nu metal up with dub step...
Vidiot: Korn "Narcissistic Cannibal"
Yeah! I KNOW! I posted a Korn video yesterday. Get off my back. Today is a special day for Korn. They released their 10th studio album "The Path Of Totality"...


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A year after the Two Towers film and videogame became huge hits, New Line Cinema and EA have reunited. Now bigger and deeper, ROTK has six playable characters, including Gandalf and Aragorn. While the gameplay is mostly hacking and slashing, there is also some nifty interactivity allowing players to launch catapults or spill cauldrons of fire. But beware: Certain levels can be difficult. Fans will find much to enjoy, but don't blame us if you're as haggard as Gollum by the time you actually finish the game.
Top Stories
- 'Power': Actress Lela Loren explains how wild scenes were shot
- Justin Timberlake is still doing the Carlton at golf tournaments
- 'The Magicians' season 2: See the premiere's first scene
- Comic-Con: See photos from the Harley Quinn costume contest
- 16 can't-miss Comic-Con Boomerangs from EW's Instagram account
- '24: Legacy' exists in same Jack Bauer universe
- 'Sherlock' Comic-Con panel reveals three key names to tease season 4


text:
Maverick Carter hints LeBron James' Nike deal is worth $1 billion
LeBron James signed a lifetime endorsement deal with Nike last December.
LeBron James signed a lifetime endorsement deal with Nike last December.
The referees in Game 1 of the Western Conference Finals between the Oklahoma City Thunder and Golden State Warriors missed a blatant travel by Russell Westbrook in the final minute of the contest on
Jose Bautista was rocked in the jaw by Texas Rangers infielder Rougned Odor on Sunday, and the Toronto Blue Jays slugger will no doubt be feeling sore for a few days.
The bad blood between the Texas Rangers and Toronto Blue Jays led to some rather ugly scenes on Sunday afternoon.
Not long after he helped the Oklahoma City Thunder advance to the Western Conference Finals by scoring a game-high 37 points on Thursday, Kevin Durant supposedly did something far more important for
The rivalry between the Pittsburgh Pirates and Chicago Cubs remains alive and well.
The Tennessee Titans knew they weren't drafting the most agile running back on the board when they took former Alabama star Derrick Henry with the 45th overall pick.
Will Wilcox masterfully tackled one of the most intimidating holes in golf on Friday when he drained a hole-in-one at The Players Championship.


text:
Right hand drive wa
1-15 of 104
2000 Mercedes Benz V280
North Vancouver, Vancouver, WAnew 1 day, 11 hours ago -
This is a "Right-Hand Drive" vehicle as well. Comes with a Passenger-side Captain chair which is equipped with an EZ Lift for loading and...
1990 Mini Cooper
Vancouver, WA05/25/2016 -
Right-Hand Drive vehicle in Mint condition and looks great. Dark-Green Metallic exterior with a White Top plus a Grey Cloth interior. Equipped...
1968 Land Rover (WA)
Spokane, WA 992082 days, 8 hours ago -
Right hand drive (New Zealand vehicle). Please call William @ 509-466-2--- to see this right hand drive vehicle.
2011 honda civic 4 door sedan
Boss, OK 747452 days ago -
Take your hand off the mouse because this 2011 Honda Civic is the car you've been hunting for. New Car Test Drive said. We found ride quality in...
1991 Toyota Hiace Super Custom 4x4 Diesel Van
Leavenworth, WA 988264 days, 18 hours ago -
Imported from Japan, Right-hand drive, Digital dash in Km. Serious 4-wheel drive with locking hubs, Push-button 4x4, Leavenworth, Washington
Jaguar E-Type XKE Roadster
Bellevue, WA 980052 weeks, 2 days ago -
Worldwide, including both left and right-hand drive examples, a total of only 7,828 3.8 litre Series 1 roadsters were built. Finding a gorgeous...
Similar cars: right hand drive jaguar
2010 MINI Cooper Clubman Base 3dr Wagon
Spokane, WA 9921206/22/2016 -
This small car is fun to drive! Light weight alloy wheels on this small car are the perfect compliment to a stylish body. This MINI Cooper has...
Certified 2013 Toyota Tundra
Spokane, WA 992121 week ago -
Only the CARFAX Buyback Guarantee can offer you the built-in peace of mind of knowing you made the right purchase. This is a well kept ONE-OWNER...
2015 ford edge sel awd sel 4dr suv
Coal Creek, WA 9802706/22/2016 -
Take your hand off the mouse because this 2015 Ford Edge is the SUV you`ve been searching for. This wonderful Ford Edge is just waiting to bring...
2013 Ford Focus 4D Sedan S
Juanita, WA 9803405/20/2016 -
Turn your nose up at the oil companies everytime you drive by the gas pumps! Washington residents only. All offers expire on close of business...
1977 Lincoln Continental mark v cartier for Sale
Tarrant, TX2 weeks, 1 day ago -
...$118.00 per month with 20 down and approved credit. This car is located and being represented for a collector in the Seattle, Washington area.
2014 mazda mazda3 4 door hatchback
Spokane, WA 9920705/20/2016 -
Drive any city's streets like you've lived there all your life using the navigation system on this Mazda Mazda3. More information about the 2014...
2014 mazda mazda3 4 door hatchback
Spokane, WA 9920705/20/2016 -
202 E North Foothills Drive, Spokane, WA, 99207 Disclaimer: All vehicles subject to prior sale. We reserve the right to make changes without...
Used 2004 Chevrolet Corvette
Richmond, VA 232252 weeks, 4 days ago -
Come see us and experience the best car buying experience in VA first hand! Proudly serving Richmond, Washington D.C. Fairfax, Baltimore...
2011 Dodge Charger SE for sale in Burlington, WA
Skagit, WA3 weeks, 4 days ago -
Yes Yes Yes Yeah baby New arrival Take your hand off the mouse because this 2011 Dodge Charger is the car you ve been looking for. This...


text:
The Adirondacks country house's main staircase railing is crafted from tree branches and logs. Notice the use of a variety of natural woods in the unfinished wood walls and the rough hewn wood block stairs.
Cork letter
rope banister
Mountain Cabin
Baby's room
License plate table
My Kind of Porch Swing-
Pretty colors
This nursery is AMAZING!!!
Wine rack as towel holder
Charging station from a shoebox and powerstrip..SMART!
Oh I definitely need this. This is one of those things that you didn't know you wanted until you saw it.
Fantastic idea!
love this for the garage or barn :)
Grrrreat idea
A built-in dog house
1 per kid...brilliant
haha great idea!!!
hidden laundry
This would be amazing!
idea: open shelf and basket for each family member (clean and sorted for them to fold!
rock wall to secret play space above rooms, there is an entrance from each kid's room to the shared space
i need one of these


text:
Could the future of highways come from the humblest beginnings down on the farm?
Injuries were reported and traffic came to a standstill mid-day Tuesday (July 19) when a construction crane collapsed onto the Tappan Zee Bridge in New York.
As the shutdown of road, bridge and rail work continues into its second week in New Jersey, a trade association representing the U.S. transportation design and construction industry has iden...
From Coatings Consult by Warren Brand
It's time for a new way of thinking. Let's first start with a story from a 60 Minu...
From Hard Hat Geek by Robert Ikenberry
Americans are great innovators. We develop the coolest technological toys. From perso...
October 25 - October 27, 2016
October 11, 2016
September 21, 2016
The PaintSquare Pro Video Series: A collection of technical presentations hosted by PaintSquare.com in cooperation with SSPC
A collection of archived webinars hosted by PaintSquare.com focused on coatings application.
A collection of archived webinars hosted by PaintSquare.com focused on coatings technology and their applications.
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Oct. 12, 2012
LOGAN, Utah - Utah State's football game at San Jose State on Saturday, Oct. 13 will be televised regionally by ESPN and broadcast live on Altitude Sports (Comcast Ch. 61, DirecTV Ch. 681, DISH Network Ch. 410). The game, which is also available to watch via the internet on ESPN3.com, is scheduled to kickoff at 2 p.m. (MT).
Utah State is 4-2 on the season and off to its best start since 1982. San Jose State is 4-1 and has won four-straight games for the first time since 2006. Overall, USU has won each of the last three games played in the series and Saturday's contest is both team's Western Athletic Conference opener.
Along with its television coverage, all Utah State football games can be heard across the state of Utah and southeastern Idaho, as the Aggie Sports Network will once again have affiliates from Logan to St. George broadcasting the games live.
KVNU 610 AM in Cache Valley will continue to serve as the flagship station for Aggie football, while affiliates in Salt Lake City, St. George, Vernal and Price will once again be part of the Aggie Sports Network.
Fans can listen to USU Football in Salt Lake City on KZNS 97.5 FM, in St. George on KZNU 1450 AM, in Vernal on KVEL 920 AM, and in Price on KRPX 95.3 FM. Every affiliate station will carry the one-hour pregame and postgame show in addition to the 50-minute weekly coaches show.
Additionally, Cache Valley/Tremonton fans can listen to the Aggie Sports Network on KVNU 102.1 FM and KLZX 95.9 FM, while Southeastern Idaho fans can listen via a KLZX translator on 105.3 FM in Montpelier, Idaho.
Along with its affiliates to the Aggie Radio Network, fans can continue to tune into all audio broadcasts free of charge via the Internet at www.UtahStateAggies.com and click on the "Listen Live" link.
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Books in history were extremely expensive prior to the printing press. In the old days, scribes were educated people who created books by hand. They knew the skills of making scrolls from animal skins or paper, then they carefully recopied existing books using inks which they fabricated themselves. Owning a book was rare and only the very wealthy had them. The reason was simple, it took a learned person perhaps a year to reproduce a single volume.
It wasn't until people like Gutenberg created the printing press that pamphlets and books were available for purchase. A scribe was no longer needed since a machine could produce the reading material far faster.
While many cities have libraries, post-collapse it's very likely that books will be burned for a variety of reasons. Some will no doubt be burned to provide heat. Some people will burn books for use as cigarette paper. Both have happen previously in history in wartime and during collapses. Religious fervor often creates censorship during those dark times, and book burning is common.
Books are among the most valuable items you possess today in your preps. No one can easily memorize the information inside them. Because they take up so much space, many preppers have gone to electronic books as a way to store them. It is possible though that due to EMP or natural disaster or lack of power that you'll be unable to utilize ebooks. That means a prudent prepper will have BOTH.
Regardless, having paper and ink is essential for prepping. Besides the knowledge we have now, you'll be journaling things by hand on a daily basis. You'll be recording how the crops are doing based upon changes you've made by soil amenities like animal manure, wood ashes, different kinds of humus, crop fruit rates, germination rates, yields, etc. You'll be writing down how well some animal feed or reproduce, or how often they get sick and what are the symptoms and what seems to help them thrive.
You'll be journaling about how your children are getting along with homeschooling. What lessons seemed to excite them? Which lessons didn't inflame their desire to learn? What should be changed when a younger child gets older?
Knowing how to make paper and ink will be important. Existing paper will most likely be burned by a lot of people. You can recycle yours into new paper. Inks can be made by things like pokeweed. All inks can fade, so understanding how to make them last is essential. Imagine writing many copious notes and then they become lost.
In ancient societies, information was often handed down from one generation to another by this means. Scrolls and books preserved old wisdom and information. The newer generation might not value that until they got older and re-read the books. Because of experience and maturity, they reassessed that information and grasped the value in it.
Please take this to heart.
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Comments about 'The coming genealogical dark ages'
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Thank you for sharing this with those of us who could not attend the Conference. I write a blog and often think I have nothing to post. But after reading this, I'm motivated to use my blog to tell these stories, memories, captions/stories of my photos, etc. I used to be a big letter writer and miss getting letters in the mail. I'm going to re-think the direction of my blog now. Thanks to Curt's advice, I'll definitely be writing more.
- 8:45 a.m. July 29, 2010
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This is true, we've lost a bunch with dying older generations just in the past 20 years. These older people who are passing are those that remembered even conflicts with Native peoples in the Utah area. We've got to capture their stories to maintain a link from then to now.
- 10:33 a.m. July 29, 2010
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|Publication number
|Publication type
|Application number
|Publication date
|Aug 29, 1989
|Filing date
|May 18, 1988
|Priority date
|May 18, 1988
|Fee status
|Publication number
|Earl R. Collins, Jr., Jerry W. Suitor, David Dubis
|Original Assignee
|The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (14), Referenced by (14), Classifications (12), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
The invention described herein was made in the performance of work under a NASA contract, and is subject to the provisions of Public Law 96-517 (35 USC 202) in which the Contractor has elected not to retain title.
The invention relates to a continuous flow lockhopper, and more particularly to a lockhopper which allows continuous withdrawal of a solid product, such as ash, from a pressurized high temperature reactor vessel while limiting loss of hot reactor gases with the product.
Conventional reactor lockhoppers operate in a batch mode, causing significant loss of energy, both in pressurization and depressurization at each batch dumping, and concomitant heat loss from the system. In addition, the airlock valves, which close off the lockhopper, operate in an extremely hostile environment--hot and abrasive--which severely limits the life of the pressure seals and valves.
During each batch dump, a substantial amount of reactor vessel gases are released to the outside air. These are often hazardous toxic gases which must be scrubbed, or otherwise purified, before final release. Even when the reactor gases are harmless, they carry away a substantial amount of heat energy which must be replaced when the reactor vessel is fired up again for the next batch.
Two additional problems have been addressed by this invention: the continuous, though much reduced, loss of reactor vessel gas, and the fact that it is not always desirable to permit steam to enter the reactor. The leakage of reactor gas causes a loss of heat energy, and gas volume which must be replaced, or in those cases where the gas is the process product, a reduction in yield. It would be highly desirable to reduce further these extra operating costs, or eliminate entirely the loss of hot gases from the reactor.
In addressing these problems in an ash lockhopper, fluidics control is employed to throttle down the flow of ash and reactor gas from the ash hopper outlet of the reactor vessel, prior to passing the flow through a pressure letdown device. The fluidics control is achieved by supplying its control port with steam generated by cooling water injected into a cooling water jacket around the reactor's ash hopper. This fluidics control represents a substantial improvement in the art to achieve continuous ash flow, along with successful flow control, pressure letdown, and an energy-efficiency greatly improved over conventional batch processes. A cyclonic separator (not shown) on the output of the system separates effluent steam and gases from the solid product.
The loss of hot gases from a pressurized high temperature reactor vessel in a continuous flow lockhopper is due to continuously dropping the process product, or in those cases where the gas is the process product, the solid by-product, both of which (the solid product and the solid by-product) are referred to hereinafter as the solid reactor product, using gravity as the moving force through a hopper. This loss is minimized by the aforesaid fluidics control using a control chamber where an equalizing pressure of fluid (air, steam or inert gas) is maintained to prevent all but a very little of the gas in the reactor chamber from passing through the control chamber with the solid reactor product. This is accomplished by introducing a pressurized control fluid through a control valve into the control chamber, and controlling the valve by means for approximately equalizing pressure of reactant gases in the reactor vessel with back pressure from the control chamber to the valve. As a result, virtually none of the reactant gases will flow through the hopper into the control chamber. The pressure of the control fluid into the control chamber is preferably controlled to be slightly greater than the pressure of gases in the reactor in order to create a spiral motion of the solid reactor product in the control chamber. That helps move the product through the control chamber into a pressure letdown means. The solid reactor product thus passes continuously through the control chamber and the pressure letdown device, where the pressure of the solid reactor product is reduced to atmospheric pressure with only a small amount of control gas outflow.
The novel features that are considered characteristic of this invention are set forth with particularity in the appended claims. The invention will best be understood from the following description when read in connection with the accompanying drawings.
FIG. 1 illustrates schematically the fluidics control employed in a lockhopper to prevent outflow of reactor gases with solid reactor product continuously removed from a reactor vessel by gravity.
FIGS. 2a and 2b illustrate schematically sectional side view and sectional plan view, respectively, of a control chamber which may be used to prevent reactor gases from escaping out of a hopper of the reactor vessel into a pressure letdown device, and from there into the atmosphere.
FIG. 2c illustrates a variant of the cross sectional plan view for the control chamber of FIG. 2b. It provides means for throttling down the flow of solid reactor product.
FIGS. 3a and 3b illustrate a variant of the pressure letdown device of FIG. 1.
FIGS. 4a and 4b illustrate another variant of the pressure letdown device of FIG. 1.
Referring to FIG. 1 of the drawings, a continuous flow ash lockhopper is disclosed by way of example of the present invention and not by way of limitation, since the fluidics control disclosed may be used in any type of reactor where the loss of reactor gases is to be eliminated, and a solid product, or by-product, is continuously drawn out.
The ash lockhopper shown allows ash to be continuously removed from a reactor vessel 10 in which a material (coal slurry) is continuously fed through an airlock valve 11 from an inlet lockhopper (not shown). The coal reacts with air to turn into ash. A grate 12 is shown symbolically under the fluidized bed of coal; it can be any one of the many conventional mechanical grates available for breaking up clinkers and large cinders. The fine ash falls down through the grate leaving high pressure and temperature toxic gases above the ash. For example, burning coal to produce heat results in ash and toxic gases. Whereas the ash may be a desirable byproduct to be carried away, the gas should not be because of its heat that may be utilized productively.
In this system, the ash is permitted to flow gradually down out of the reactor vessel past a normally open backup valve (not shown), which is closed only during maintenance and emergencies. The ash, cinders and clinkers in an ash lockhopper 13, which are still very hot, may be exposed to a stream of quench water, which explosively destroys the cinders and clinkers, and reduces them to the size of ash granules. The water flashes to steam on contact with the hot ash. In the past, this quenching has taken place in, or after, the ash lockhopper 13, and the steam has been vented to the outside air, not into the reactor vessel. In this invention, the steam may enter the reactor vessel and mix with the toxic gases. As the toxic gases are cooled, the steam condenses and can easily be removed, along with the water of combustion, by a cyclone separator (not shown) at the system output.
A water jacket 14 surrounds the quench chamber; some of the heat in the ash lockhopper 13 may be used to generate steam which may then be used as a control gas for operating a fluidics flow control chamber 15 at the lower end of the lockhopper 13. The flow control chamber is a vortex-type flow control chamber, which will be described with reference to FIGS. 2a, b and c. Its functions are to throttle down the flow of ash and steam from the ash lockhopper 13 to a slow enough flow that full ash size reduction can take place, and most importantly, to maintain the high pressure of the reactor vessel, i.e., to eliminate loss of reactor gases. An emergency and maintenance shutoff valve (not shown) may be inserted between the ash lockhopper 13 and the flow control chamber 15; it is normally open during continuous flow operation.
The falling cinders, clinkers and fine ash settling in the bottom of the reactor vessel 10 fall down through the ash lockhopper 13. From there the reactor byproduct passes into the control chamber 15. This chamber effects flow control of the product by varying the pressure and velocity of a control stream of fluid in line with the product stream flowing from an input port 23 (FIGS. 2a, b and c) into the control chamber 15. Impinging control fluid creates a vortex (cyclonic flow) of the ash which acts as a throttle on the ash flow through the control chamber 15, as will be described more fully with reference to FIG. 2a, 2b and 2c.
The loss of gases from the reaction vessel (contained between the grate 12 and the bottom of the reactor vessel where ash falling through the grate is collected) is eliminated by control of the pressure of the control fluid stream into the control chamber 15. Although steam is indicated as the control fluid, it may be air or inert gas as well, or a combination of these. This control fluid is introduced into the control chamber 15 through a control valve 16 at a pressure equal to or greater than the pressure of toxic gases in the reactor vessel 10. Once the gas pressure in the control chamber is set equal to or greater than the pressure of toxic gases in the reactor vessel, there will be no pressure gradient to cause reactor gas to exit the reactor vessel through the lockhopper 14.
A pressure control means 17 compares the pressure of the reactor gases, and the pressure of the control gas in the control chamber 15, to properly balance them by operation of the control valve 16. Thus, the high equalizing pressure of control gas from a source (shown here as steam from the cooling water jacket) is introduced at a pressure equal to or slightly greater than the reactor pressure. That arrangement allows very little if any of the reactor gases to flow with the ash through the hopper into the control chamber 15, but ash, which is of higher specific density than the control gas, will pass into the control chamber 15 through a throat 18 of a smaller diameter than a throat 19 into a pressure letdown device.
The fine ash and some control gas steam passes through the pressure letdown device 20 to reduce the pressure of the ash and control gas to that of the atmosphere. That device 20 is preferably a modification of the one shown schematically in FIG. 1, namely a modification as disclosed in FIGS. 3a, b and 4a, b. In these devices a number of stages are used, each stage causing a small pressure drop and allowing a slow flow of the fluid stream (ash and control gas) such that erosion of the device by the abrasive particles carried in the fluid stream is held to a minimum. The pressure of ash, and control gas surrounding the ash, is gradually reduced as the ash cools. As a consequence, ash is recovered at an outlet throat 21 of the pressure letdown device with only a small volume of control gas (steam) outflow. The steam is separated from the fine ash by a cyclone separator (not shown).
While this process of recovering ash is carried out, fresh material (coal slurry) is continuously introduced into the reactor vessel 10 through the airlock valve 11 normally open, but which may be regulated by, for example, a sensor 22 near the top of the reactor vessel to produce a control signal that reduces flow of the material until the level of coal slurry drops and is no longer being sensed. In that manner, the reactor may be continuously fed input material to produce a continuous flow of reactor output material without significant loss of toxic gases from the reactor vessel.
Control of the ash inlet to the chamber 15 through the throat 18 will change flow rate of the ash, which is impelled downwards solely by gravity. Although flow control is also dependent on control fluid (steam) pressure, and changing the control setting will be reflected in a change in the pressure drop across the ash inlet throat 18 such that there will be some interaction, precise ash inlet control and control fluid pressure settings can be accomplished rapidly by the use of automatic control means employing pressure sensing. This will keep reactor gas losses caused by flow adjustments to a minimum. Once a steady state is reached, virtually all of such gas losses will cease.
Referring now to FIGS. 2a and 2b, the outlet port of the control chamber 15 is schematically illustrated at 22 in the geometric center of the control chamber, while the input port 23 is offset from the center and directly in line with a control inlet port 24 for the control fluid (steam). The control fluid enters the internal chamber 15' through the inlet port 24 and impinges on the stream of reactor product entering through the port 23. The result is creation of a vortex which circulates within the chamber 15' along the sidewalls thereof. As the flow of control fluid is increased, the vortex is accelerated, and enlarged in diameter, thus delaying the exit of the product flow through the centrally located output port 22. This has the effect of decreasing flow rate and increasing the hydraulic heat loss between the input port 23 and the output port 22.
The control fluid pressure and velocity are controlled by controlling the input pressure of the control fluid and the size of the inlet port 24. The higher the control fluid pressure, the greater the velocity of the control fluid jet impinging upon the reactor product stream coming in through the inlet port 23. Thus, the cross sectional area of the inlet port 24 is an important determinant of the effect of the control fluid flow on the vortex of the product stream. In any one device, this area of port 24 is fixed. If this area does not fit a particular set of stream input/output conditions, the device must be changed to another having a different ratio of supply and output port cross sectional areas. In laboratory conditions, this device exhibits a ratio of as much as five to one. However, in field conditions, it is more usual to obtain ratios of as low as two to one.
FIG. 2c illustrates a control chamber with means for varying the control ratio comprising a D-shaped sector 25 rotatable about its pivot by a shaft 26 such that it can throttle down the cross sectional area of the control port 24, open it to a maximum, or set it to any intermediate setting. This also affects volume and port heat loss, but if control gas supply pressure can be varied, independent control of control gas volume and velocity is possible. This enables adjustment to a wider range of control conditions, and the ability to maximize control efficiency. Fluidics control theory indicates an improvement in control ratio of at least two to one over conventional control devices.
The pressure letdown device 20 in the fluid stream after the control chamber 15 may be a device of the type described in U.S. Pat. No. 4,418,722 filed by James S. Kendall and John V. Walsh and assigned to the National Aeronautics and Space Administration. Pressure letdown devices of this type consist of a series of pressure letdown stages, each stage having horizontal, flat or V-shaped baffles with successively larger openings through the baffles and/or progressively more openings at each stage. Since reactor products expand as pressure is reduced, each baffle of the pressure letdown device should be provided with an integrated area of opening greater than in the preceding baffle. However, it has been found that it is sufficient to use sloping baffles as shown in FIG. 1, with a casing of uniform diameter, and an opening in the successive baffles of sufficient area to accomodate the flow of the solid reactor product through the throat 19, given that the reactor product expands as the pressure is reduced. Thus, to accomodate the progressive expansion of reactor product in the letdown device having sloping baffles, an opening at the bottom of each successive baffle may be made progressively larger.
Another variation illustrated schematically in FIGS. 3a and 3b is to employ parallel baffles 30 in a cylindrical casing 31 of uniform diameter, but instead of apertures in the baffles, which increases in number and/or size from one baffle to the next, there is provided in each baffle an annular opening 32 of successively larger diameter from one baffle to the next, with the center part 33 of each annular opening constituting a disk of successively larger diameter mounted on a shaft 34 rotated on the axis of the cylindrical casing. However, each such circular disk is mounted on the shaft with an offset from its center, as shown in FIG. 3b, so that the annular opening has a varying width, and as the disk is rotated the gap varies from, for example, 150" to 154". This is not for the purpose of grinding the solid reactor product particles, but to simply break them apart as they pass from baffle to baffle with an ever increasing annular opening from baffle to baffle to accomodate the expansion of the particles as pressure is reduced.
The phase of rotation from one disk to another is preferably 180� so that the probability of the particles striking the next disk in succession is increased. To further enhance that by more positively increasing the tortuous path of the particles passing through the pressure letdown system, the annular opening for each baffle having an offset disk (with the offset direction alternated from disk to disk for rotation of adjacent disks 180� out of phase) may have sides sloped to provide a general direction toward the axis for particles passing through each baffle, as shown in FIG. 4a where the same reference numerals are shown as in FIG. 3a for the same corresponding parts. The "tortuous path" thus assured is consequently increased by vector redirection at each baffle for increased energy redirection. As the walls of the annular openings wear, the total area of the opening may be maintained substantially constant by adjusting the axial position of the shaft. This is made possible by the sloped walls of the annular openings since adjusting the axial position of the shaft moves the disks further into the stationary part of each baffle thus making the annular opening smaller for each baffle.
If some grinding of the particles is desirable, a spiral configuration of a groove on the surface of the disk annular opening may be provided as shown in FIG. 4b. This grinding action would provide clearing of any adhered particles to avoid clogging. The spiral groove 35 on the edge of the disk can be made deeper than is necessary and partly refilled with a spiral brass insert in the spiral groove 35 of each steel disk. The brass insert, in wearing away faster than the steel disk wears, would provide a constant spiral "bite". The steel of the disk extends further and wears slower, while the brass insert wears faster because it is softer than steel, but, because the brass is recessed, the rate of wear of both would be of the same approximate rate.
The invention realistically provides for the first time an ash lockhopper system that will attain a high degree of energy efficiency, eliminate reactor gas loss so as to obtain the highest possible product yield while permitting a controllable continuous ash flow, and continuous reactor processing.
While this invention is primarily intended to convert a gas producing, reaction coal burning furnace from batch to continuous flow operation, the system has many different application possibilities. For example, fluidized-bed reactor systems, such as those used in the chemical and petrochemical industries, would be benefitted by use of this system. Since the invention essentially operates as a solids/gas separator, it has many applications in the fields of solids separation, dust separation, and the like.
Although particular embodiments of the invention have been described and illustrated herein, it is recognized that modifications and variations may readily occur to those skilled in the art. Consequently, it is intended that the claims be interpreted to cover such modifications and variations.
|Cited Patent
|Filing date
|Publication date
|Apr 16, 1943
|May 6, 1947
|Allen Sherman Hoff Co
|Automatic dust removing system
|Oct 29, 1945
|Mar 25, 1952
|Babcock & Wilcox Co
|Material discharge mechanism
|Feb 24, 1951
|Jul 26, 1955
|Houdry Process Corp
|Solids transfer leg
|Aug 15, 1955
|May 13, 1958
|Metallgesellschaft Ag
|Depressurizing of ash discharge locks and similar chambers
|Oct 24, 1968
|May 11, 1971
|Spyropoulos Chris E
|Distributed control flueric amplifier
|Feb 24, 1975
|Feb 3, 1976
|Institute Of Gas Technology
|Coal ash agglomeration device
|May 12, 1976
|May 17, 1977
|Institute Of Gas Technology
|Valve for ash agglomeration device
|May 4, 1977
|Dec 26, 1978
|Owen, Wickersham & Erickson
|Fluid flow regulator
|Dec 9, 1980
|Jun 21, 1983
|Bowles Fluidics Corporation
|Fluid flow control element having movable valve and method
|Jul 13, 1981
|Aug 9, 1983
|Phillips Petroleum Company
|Discharge of solids
|Apr 30, 1981
|Dec 6, 1983
|The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration
|Pressure letdown method and device for coal conversion systems
|Mar 10, 1983
|Dec 27, 1983
|United Kingdom Atomic Energy Authority
|Fluidic control devices
|Jan 25, 1982
|Jul 10, 1984
|Stone & Webster Engineering Corp.
|Solids flow regulator
|Sep 8, 1987
|Dec 13, 1988
|Westinghouse Electric Corp.
|High pressure and high temperature ash discharge system
|Citing Patent
|Filing date
|Publication date
|Mar 20, 1995
|May 13, 1997
|Chemical Lime Company
|Method and furnace for decomposing solid waste materials
|Sep 23, 1993
|Jan 13, 1998
|Abb Carbon Ab
|Method and device for discharging particulate material from a pressurized container
|Jun 19, 2000
|Feb 7, 2006
|Foster Wheeler Energia Oy
|Method and apparatus for treating high pressure particulate material
|Aug 10, 2010
|Southern Company
|Method and apparatus for the separation of a gas-solids mixture in a circulating fluidized bed reactor
|May 28, 2008
|Sep 28, 2010
|Rainbow Conversion Technologies, Llc
|Pyrolysis apparatus
|Oct 26, 2010
|Jc Enviro Enterprises Corp.
|Method and apparatus for generating combustible synthesis gas
|May 22, 2012
|Saudi Arabian Oil Company
|Non-shedding strainer
|Jul 15, 2005
|Jan 18, 2007
|Jc Enviro Enterprises Corp.
|Method and apparatus for generating combustible synthesis gas
|Mar 9, 2007
|Sep 11, 2008
|Pannalal Vimalchand
|Method and apparatus for the separation of a gas-solids mixture in a circulating fluidized bed reactor
|May 28, 2008
|Dec 3, 2009
|Bruce Shuman
|Pyrolysis apparatus
|Dec 24, 2008
|Jun 24, 2010
|Muhsen Shobbar Hashim Al-Sannaa
|Non-shedding strainer
|Dec 20, 2009
|Jul 14, 2010
|Centrum dopravniho vyzkumu, v.v.i.
|Capsules for concrete from a fiber and ice and method of their production
|Mar 19, 1996
|Sep 26, 1996
|Chemical Lime Company
|Method and furnace for decomposing solid waste materials
|Sep 10, 2014
|Mar 26, 2015
|L'Air Liquide, Soci�t� Anonyme pour l'Etude et l'Exploitation des Proc�d�s Georges Claude
|Gasification plant and method for pressurizing its ash lock
|U.S. Classification
|International Classification
|Cooperative Classification
|European Classification
|May 18, 1988
Owner name: CALIFORNIA INSTITUTE OF TECHNOLOGY, THE, PASADENA,
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Owner name: UNITED STATES OF AMERICA, THE, AS REPRESENTED BY T
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST. SUBJECT TO LICENSE RECITED;ASSIGNOR:CALIFORNIA INSTITUTE OF TECHNOLOGY, A CORP. OF CA;REEL/FRAME:004892/0800
Effective date: 19880411
Owner name: CALIFORNIA INSTITUTE OF TECHNOLOGY, THE, CALIFORNI
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:COLLINS, EARL R. JR.;SUITOR, JERRY W.;DUBIS, DAVID;SIGNING DATES FROM 19880404 TO 19880408;REEL/FRAME:004892/0796
Owner name: UNITED STATES OF AMERICA, THE, AS REPRESENTED BY T
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:CALIFORNIA INSTITUTE OF TECHNOLOGY, A CORP. OF CA;REEL/FRAME:004892/0800
Effective date: 19880411
|Feb 26, 1993
|Fee payment
Year of fee payment: 4
|Apr 8, 1997
|Maintenance fee reminder mailed
|Aug 31, 1997
|Lapse for failure to pay maintenance fees
|Nov 11, 1997
|Expired due to failure to pay maintenance fee
Effective date: 19970903


text:
The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: HW. Performed the experiments: HW ESK TS RS. Analyzed the data: HW. Contributed reagents/materials/analysis tools: Provided E4bp4-deficient mice: YM MK. Provided Il15-mutant mice: TY HY. Wrote the paper: HW MT. Built the initial constructs, generated mouse lines of Il17rb-deficient mice: HW. Designed FTOC experiments: HKawamoto. Generated Il17rb-deficient embryonic stem cell lines: HKoseki. Supervised the project: MT.
The authors have declared that no competing interests exist.
Four distinct subsets of invariant natural killer T (NKT) cells are shown to differentiate in the thymus, then migrate to peripheral tissues where they retain their phenotypic and functional characteristics.
There is heterogeneity in invariant natural killer T (
T cells are a diverse group of immune cells involved in cell-mediated acquired immunity. One subset of T cells is the innate-like invariant natural killer T (
Natural killer T (NKT) cells, unlike conventional T cells bearing diverse antigen receptors, are characterized by the expression of an invariant T cell receptor (TCR), Vα14Jα18 paired with Vβ8, Vβ7, or Vβ2 in mice
It is speculated that the ability of
There is also further heterogeneity of CD4+
The emergence of functionally distinct subpopulations of
We previously identified a fraction of splenic CD4+
(A) FACS profile of spleen and liver mononuclear cells in WT,
We then analyzed the frequency of IL-17RB+ subtypes among α-GalCer/CD1d dimer+
By using
To examine the functional activity of
(A, B) FACS profiles of thymus (A) and enriched thymic
In order to determine if
To confirm the differences among subtypes of
In order to investigate functional differences in the IL-17RB+ and IL-17RB− subsets of
In a previous study, IL-17RB+
(A, B, D, H) Quantitative PCR analysis of thymic
We then investigated the gene expression level in cells derived from Stages 1 and 2 by FT organ culture (
Based on these findings, we analyzed potential production of cytokines from these thymic
We then further analyzed cytokine production after α-GalCer activation. Sorted
We also analyzed the expression profiles of cytokine receptor genes.
The chemokine receptor expression patterns are also distinct among thymic
Distinct expression of chemokine receptors among thymic
(A–C) FACS profile of peripheral
To confirm the distribution profiles of each subtype in the periphery, we performed intracellular cytokine staining after PMA plus ionomycin stimulation (
We next compared global gene expression profiles of CD4− or CD4+, IL-17RB+ or IL-17RB−
(A) Global gene expression profiles in
In order to confirm the stability and plasticity of
We further analyzed in cytokine production of splenic
Both thymic and peripheral
One of the candidate genes is E4BP4, a mammalian basic leucine zipper transcription factor that regulates IL-10 and IL-13 production not only by CD4+ T cells and regulatory T cells but also by
Therefore, we analyzed the role of
(A, B) Quantitative analysis of
We then investigated the role of IL-17RB+
Therefore, we attempted to determine whether or not the CD4− IL-17RB+
(A) Schematic showing the protocol for RSV-induced AHR. Mice were i.n. administered with RSV (106 pfu) or PBS alone as a control 4 times at 10-day intervals. Mice were i.p. immunized with rec Gs/alum (50 µg/2 mg) 4 d after first RSV infections. Three days after the last RSV administration, mice were exposed i.n. to rec Gs and were measured 1 d later. (B) Development of RSV-induced AHR in BALB/c, but not in
In the present study, we identified IL-17RB− and IL-17RB+ subtypes of
It has been proposed that
It has reported that IL-15 plays an important role in the expansion of
In the previous reports, the IL-17A-producing subtypes were proposed to be contained within the CD44hi NK1.1− CD4− RORγt+ subpopulation
In the periphery, the tissue distribution of the
The study described here indicates that
B6 and BALB/c mice were purchased from Charles River Laboratories or Clea Japan, Inc.
Cytokines except IL-22 in culture supernatants and BAL fluids were analyzed by cytometric bead array (BD Biosciences) according to the manufacturer's protocol. IL-22 was quantified by an ELISA reagent set (eBioscience) according to the manufacturer's protocol.
Cells were analyzed by FACS Calibur (BD Biosciences) or FACS Canto II (BD Biosciences) and sorted by FACS Aria (BD Biosciences). Antibodies (BD Biosciences or eBioscience) used for staining mouse cells were as follows: FITC or APC-Cy7 anti-TCRβ (H57-597), Pacific blue anti-CD4 (RM4-5), FITC anti-CD44 (IM7), PE-Cy7 anti-NK1.1 (PK136), PE anti-CD122 (TM-β1), FITC anti-CD8α (53-6.7), PerCP-Cy5.5 anti-CD25 (PC61), PE anti-IFN-γ (XMG1.2), PE anti-IL-4 (11B11), PE anti-IL-10 (JES5-16E3), PE anti-IL-13 (eBio13A), PE anti-IL-17A (TC11-18H10), and PE rat IgG1 (A110-1). Biotinylated anti-mouse IL-17RB (B5F6) was generated previously
The procedures for the coculture with a deoxyguanosine (dGuo)-treated FT lobe under high oxygen submersion conditions have been described in detail previously
Intracellular cytokine staining was performed as described previously
PCR primers and probes were designed with Universal ProbeLibrary Assay (Roche) or with TaqMan Gene Expression Assays (Applied Biosystems). Sequence of primers and probes in the latter case are shown in
Gene expression detected using microarrays was normalized by the quantile normalization method
Strain A2 of human RSV was used in this study. The general protocol for analyzing airway remodeling during RSV infection in mice is as follows: AHR was induced by sensitizing and challenging with OVA/alum (3–4 times) and/or infection with RSV (3–4 times), and then challenging with OVA, resulting in the examination of various pathological endpoints as previously described
Airway function was measured for changes in lung resistance (RL) and dynamic compliance in response to increasing doses of inhaled methacholine (1.25, 2.5, 5, 10, and 20 mg/ml) by using an invasive FlexiVent (SCIREQ Scientific Respiratory Equipment Inc.).
After measurement of AHR and sacrifice, the mouse trachea was cannulated, the lungs were lavaged twice with 1 ml PBS (10-fold PBS dilution), and the BAL fluid was pooled as previously described
The statistical significance of differences was determined by
Generation of
Global gene expression profile in thymic
In vitro cytokine production by thymic
Differential gene expression and cytokine production among thymic
Cytokine gene expression in
Potential of cytokine production from
Quantitative RT-PCR analysis of
Cytokine production by splenic
Expression of recombinant RSV-Gs protein. (A) Schematic representation of RSV-G proteins. Membrane form (Gm, upper) and soluble form (Gs, middle) of RSV-G were shown. Recombinant RSV-Gs protein (rec Gs) was expressed as a fusion with a mouse IL-2 leader sequence and a C-terminal tag (BirA-6His). (B) Western blot analysis of the culture supernatant after transfection of the rec Gs expression vector into HEK293 cells. Expressed rec Gs was biotinylated by the BirA enzyme and detected by stereptavidin-HRP. Rec Gs is a highly glycosylated mucin-like protein, resulting in a diffuse band in the region of 25–120 kDa.
Primers and probes for quantitative real-time PCR used in this study.
We thank S. Inoue, K. Kakimoto, S. Sakata, and Y. Nagata for technical assistance; T. Tashiro and K. Mori for α-GalCer synthesis; P. D. Burrows for comments on the manuscript; and N. Takeuchi for secretarial assistance.
airway hyperreactivity
bronchoalveolar lavage
invariant natural killer T
retinoic acid receptor-related orphan receptor
respiratory syncytial virus


text:
John Patrick
Former VP of Internet technology at IBM & Author of "Health Attitude: Unraveling and Solving the Complexities of Healthcare," delivering solutions for patients, providers, payers & policymakers more
Respected journalist & 35-Year veteran of Fortune Magazine
Authority on redefining healthcare in post-reform America
Expert in the future of healthcare reform and information technology
Award-winning Healthcare CEO with 40 years experience
Barbara Hannah Grufferman
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Neurosurgeon and authority on longevity and disease prevention
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One of America's most respected TV journalists and two-time winner of the "Best in the Business" by the American Journalism Review, Brit Hume is a senior political on Fox News Channel. more
5-Time Emmy Award Winning Actor for "Night Court" & "Boston Legal"
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Congrats to Dr.. Carl Hammerschlag
April 2016...Phoenix Magazine features the Maestros of Medicine. While exciting, innovative and disruptive things happen in medicine, who pulls the strings, pioneers the research and performs the operations that keep the Valley at the forefront of medical advances? Who are the most powerful players in Valley healthcare today? Dr. Carl Hammerschlag is selected in the 25 Maestros of Medicine.Click Here.
Read more about Carl Hammerschlag, MD
Future Solutions for Healthcare - MedTech Chat Podcast with Dr. John Patrick
We would like to share the podcast where MedTech Chat talked with Dr. John Patrick asking him to share his medical predictions for the future of healthcare. The podcast captured many of the key aspects of healthcare he has been discussing with journalists over the past few months, based on his latest book: Health Attitudes: Unraveling and Solving the Complexities of Healthcare. Click Here.
Read more about John Patrick
New Release: Dr. Melina Jampolis - The Doctor on Demand Diet
Dr. Melina combines both the psychology of weight loss and the best available nutrition science to give you a 3 phase customized plan that is truly livable and will allow you to lose weight and keep the weight off. You don't have to give up any food groups and it works - just see what some of the test dieters with whom I had no interaction have to say. Check it Out! HERE
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Dr. John Patrick Joins Speakers On Healthcare
We are proud to announce that Dr. John Patrick has selected Speakers On Healthcare to partner on his speaking career. He is gaining national attention on his latest book: Health Attitudes: Unraveling and Solving the Complexities of Healthcare and has been invited on several media outlets. Recently MedTech Chat invited him to reveal 5 medical predictions for the future of healthcare. Click Here.
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Memory configuration for Gkill DDR2 1066 with M3A78-EM board
Last response: in Motherboards
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text:
This was the second year we've participated in the Christmas in July linkup! I really love this blogging community and the different opportunities that present itself. While I don't say yes to every gift exchange (it can get kind of costly, especially with the shipping), there are a few annual exchanges that I love doing, this being one of them. I love the idea of meeting new blogging friends and Noah absolutely loves getting packages in the mail! This year I just so happened to receive and send to bloggers that I already "know" and love. We were paired up with Julie and Myles, from The Everyday Momma, who I met when we were paired up for Stephanie's (Wife Mommy Me) Snail Mail Exchange. It was really fun writing back and forth with Julie, so I was even more excited when I saw a package from her and Myles arrive on our door step!
^^^ I love that I just happened to get a photo of Noah sitting on the box... just like last year!
Julie and Myles, from The Everyday Momma, sent us quite the package. Noah was so excited to open the box and I was amazed at how many things he kept pulling out of it! It really did feel like Christmas with all the goodies to unwrap. And it kind of looked like the Christmas aftermath with all the paper spread out over the floor.
Julie was so sweet and included a few things for me too... some travel cups, lip balm, and some cute stationery from Target. Noah was really excited for all the things he got! He got this Disney board game where you make the pieces out of modeling clay. Since Noah loves play-doh and board games, he was a huge fan! He also got some bubbles and chalk paint! Over the course of the week, Noah had a blast playing with each of his gifts (and got a haircut).
Head on over to Chasin' Mason to see what I sent Liz and Mason. Liz and I were cracking up when she sent me the email notifying me who I was paired up with since she organized the whole gift exchange! It was pretty comical for her to fill out the standard email template but with her own information.
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Derek Carr Interview: Season Outlook
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The name of any player on your team is just a name. Add the label "All-Pro" before his name, and he becomes a bit more mythic.
Every year, the Associated Press, along with other journalistic bodies, casts their votes for the NFL's All-Pro team, a starting lineup of the best and brightest from the previous season. If intergalactic overlords challenged us to a game of football, to determine the fate of the galaxy, this would be the squad we'd send into battle.
It's like the Pro Bowl, only with slightly less bias and homerism. For the most part, the AP's selections are realistic, with the occasional snub here and there. In the grand scheme, it means nothing but a small nod to a player's efforts during one season, and gives him a moniker that can be used to justify his greatness, even after his knees and shoulders are shot beyond use.
So ultimately useless as it may be, I'm all about reveling in useless. Here's my All-Pro picks after a month of action.
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New Bleeding Through Song
i dig it so fuck a beat n go acapella
I think I'd probably enjoy this more if they dropped the keys. It just sounds cheesy and unnecessary sometimes. Song was decent though.
The keys are def a part of what make them who they are but they are way overwhelming in the mix.
yeah but martas presence onstage makes up for it.
Yeah they sound.. almost comical in this song..
These guys haven't been good in like 6 years or something
Declaration was pretty good
love lost in a hale of gunfire is sick live
Declaration was awsome, self titled blows tho.
Digging: Ilaria Graziano - Yoko Kanno produce Cyber Bicci
Even when I listened to shitty music as a kid - I never really liked this band. A couple of songs from The Truth was all I could manage.
Really don't like the more raw, thrashier sound they've had since their last album. Delcaration was what this band was supposed to sound like, not fucking Slayer with breakdowns and keys.
sounds like devil driver
devildriver doesnt have keyboards
you don't need to not have keyboards to sound like devildriver. just yell in the mic like you're taking a poo
yeah.. because DD is a singer alone taking a crap..
"Really don't like the more raw, thrashier sound they've had since their last album. Delcaration was what this band was supposed to sound like, not fucking Slayer with breakdowns and keys."
I agree, sir.
I like this song better than most songs from their last album. "Declaration" was their masterpiece IMO. However, I am still looking forward to this album. I hope it's more like "Declaration" meets "the Truth."
Masterpiece what the fuck.
it was their best album, i dont think it was a masterpiece tho
i think that was an hardcore album
i thought Declaration was absolutely spectacular, hopefully the new album returns to that sound
Declaration was pretty good (2)
love lost in a hale of gunfire is sick live (2) After a long 7 year wait finally saw them live, and it was definitely one of my favorite lvie shows of all time, never moshed that hard in my life
Song is decent at best until that weird synth line comes through. Im expecting album to be better.
Digging: The Kovenant - Nexus Polaris
yeah these guys are ridiculous live
Song ruled
Is this actually alright? Declaration was pretty good but everything else they've done is bad.
They were never good.
oh nice
song sucked
Portrait of the Goddess and This Is Love are some of the best records in the early stages of the 2003 upward metalcore craze.
the truth >>> all
Digging: Arizmenda - Beneath This Reality of Flesh
Truth was a 3 at best. I liked it including the ballad but more polished and mainstream than the other stuff.
the truth was easily their most succinct release, everything else has too much filler
I'm with Spirit for once (yay)
Songs like Distortion Devotion, Sister Charltan, There Was A Flood, and Divide The Armies are some of my favorite B.T tracks so i'm expecting them to bring the jamz The Great Fire.
hell yeah ty
Declaration was and still is incredible. This song is good but im sure this album wont touch Declaration.
yea Declaration was pretty cool. still haven't really listened to these guys much in the last 3 years or so though.
Digging: Y&T - Earthshaker
I never heard anything from these guys. I will check this out... What's their best song tho? Any suggestions?
Love Lost in a Hail of Gunfire is the only thing still worthy of giving a shit about from these dudes
The only one I've heard all the way through is The Truth and it's alright
Hey andcas that song was pretty tight man... The vocalist is pretty good. Good song def
the truth is their worst album, imo
get declaration, metalcore with a tiny bit of black metal
Ok I have a weird question and I'm not necessarily talkin bout this band but I'm curious cuz I'm not a big genre stickler.... How come sometimes you'll have band a that's labeled a deathcore band and band b that's labeled a metalcore band..... And the metal core band will have way more death metal influence than the deathcore band but people label them as metalcore? I just don't understand this..... Personally.. I think the difference between some core bands is minimal or barely noticeable... For instsance.... Parkway drives first cd was labeled metalcore .... But there is certainly a ton of melo death influence ... And emmure almost everyone says is deathcore ...but I can't really hear much death metal at all! Not tryin to start a stupid genre argument .. just wanna hear some oppinions. Merry Christmas everyone
Anyone that says Declaration isn't their best album is a retard. Merry Christmas fuck you.
If I told you the truth now. yadadadadadadaddada blaaaaaahhhh
that song sounded like any random track off either declaration or their s/t. these guys have really lost it
pretty boring
@tommy, genres are usually categorised by the masses. I mean, here in Australia Parkway Drive is called hardcore, since they're part of our 'hardcore scene'. The majority of the fans outside Australia call them metalcore. You might see a melo-death influence in them, but that doesn't make them deathcore. The majority of their music sticks by the formulas of metalcore, hence making them a metalcore band. Make sense?
Portrait of the Goddess and This Is Love are some of the best records in the early stages of the 2003 upward metalcore craze.
Pretty much truth right there.
Digging: Gas - Pop
Probably because i've been listening to the band, liking them for so long but B.T was my favorite live performance of all time. I hope this record rules and hope they come to Ft Lauderdale again.
A second song. This one I really dig.
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A New Way to Create Finding AidsJuly 22nd, 2016
Yesterday, WNYLRC hosted a workshop on "Creating Finding Aids with Empire ADC." This is part of the Empire Archival Discovery Cooperative (EADC) project that we are cooperating on with the other library councils around the state. It allows our members to easily create DACS-compliant finding aids, and have them hosted on a statewide portal. The project uses an online tool called the EADitor that allows you to create your finding aids by filling in the appropriate fields.
Laura Streett from Vassar College, along with Jennifer Palmentiero from the Southeastern New York Library Resources Council, gave an informative presentation and gave everyone a chance to practice creating finding aids for hypothetical archival collections.
Even if you didn't attend yesterday's workshop, you can still get involved. The EADC website is already live, so you can take a look at the finding aids that are already there.
Contact WNYLRC's Digital Services Coordinator Jaclyn McKewan if you would like to use the site to create your own finding aids. She will work with you to arrange training on the tool and getting an account set up.
For more background on the project, watch the recording of a webinar held in May.