text:
Cleocin Pills Licensed Store
Looking for a cleocin? Not a problem!
Click Here
For more information about cleocin have a look at Pharmacy Lookup.
Guaranteed Worldwide Shipping
Discreet Package
Low Prices
24/7/365 Customer Support
100% Satisfaction Guaranteed.
But gaining information regarding the pharmacy is the best thing to do before you shop, through very useful online pharmacy reviews. The first main option is the Pharmacy Technician Certification Board. The medicinal virtues of roots will often be found in their alkaloid content, which dissolves quite slowly into water. They work exactly like other personal savings accounts. One must follow some simple steps to buy medicine readily available pharmacies.
When a person comes up on the counter which is visible intoxicated by something, it could be a scary location to be. There are dalacin-c cleocin waar te koop a great deal of details a pharmacy technician have to have to do and be knowledgeable that is why passing the PTCB certification can be a have got to. Smile and split eye-to-eye contact between your entire interviewers as much as possible when you might be speaking and keep eye contact about the person asking the questions. When you get on the pharmacy do not be afraid to ask plenty of questions including whether your prescription is around the $4 list at both locations. Americans will be more aware now than ever before concerning the serious health risks associated with using tobacco, whether it is smoking cigarettes, smoking out of the pipe, or using chewing tobacco.
To that end, PTCB publishes a list of the actual bibliography of publications from which the certification test is created. This particular service provides numerous advantages you may not even knew existed. A few states including Florida now acknowledge pharmacy technicians as professionals. Whether you're trying to obtain the dosage that works right for you or searching to dalacin-c cleocin waar te koop get a particular medicine which you were prescribed but is currently hard to find, a compounding pharmacy is where you are able to dalacin-c cleocin waar te koop find the proper help. Those who're in commercial laboratories are considered pharmaceutical industry pharmacy technicians.
Sure it is critical to pay attention in your competition, yet it's not always the only thing with your market analysis you have to worry about. Thankfully, as I stepped beyond dalacin-c cleocin waar te koop line, a woman stepped up by my side and said she would be glad to be my friend. , or Gmail, automatically remove the junk emails out of your inbox and place them in the separate folder. (Ginger has become used in hospitals for post-operative nausea. The internet has transformed businesses and lives in ways than we're able to have thought imaginable.
Most technicians work 35-45 hours weekly in hospitals and the ones retail pharmacies which are open twenty-fours a day. It is important to keep the junk email filter up-to-date to allow for Outlook in blocking pharmacy spam on Microsoft Outlook. However, be aware that not all websites using the. In spite from the differences in duties, you will find requirements that are similar no matter where the pharmacy tech works:. The function of implementing these types of courses in the curriculum is usually to encourage future technicians to become actively associated with community matters and also to stay up-to-date with social issues that affect their local communities.


text:
Reading mode: Light Dark
Forum indexFujifilm X System / SLR TalkChange forum
Selling old gear - Best methods?
Started Apr 28, 2014 | Discussions thread
Shop cameras & lenses ▾
Evan Effa OP • Veteran Member • Posts: 3,342
Re: Another vote for FM
In reply to jl_smith • Apr 28, 2014
Thank you folks.
I have not been a frequent poster on Fred Miranda or POTN even though I have visited there many times & look daily at the tilt shift threads. I didn't realize that I could use my feedback from other sites as a reference.
I also did not realize that there was a sellers forum on DPReview (Duh).
I will see whether I can use the more Photography specialist forums before I resort to eBay.
I also have never sold anything using PayPal so will have to look into the mechanics of that.
Any hazards to watch out for? (I had one fellow offer to purchase the 70-200/2.8 lens I have listed on Craigslist for more than I listed so long as I shipped it to his cousin. He wanted my PayPal info but I declined, suspecting a scam...)
-- hide signature --
Evan Effa's gear list:Evan Effa's gear list
Fujifilm FinePix S2 Pro Fujifilm XF 18-55mm F2.8-4 R LM OIS Fujifilm XF 55-200mm F3.5-4.8 R LM OIS Fujifilm XF 10-24mm F4 R OIS Canon EF 16-35mm f/4L IS USM
Reply Reply with quote Complain
|Post (hide subjects)
|Posted by
|Apr 28, 2014
|Apr 28, 2014
|Apr 28, 2014
|Apr 28, 2014
|Apr 28, 2014
|Apr 28, 2014
|Apr 28, 2014
|Apr 30, 2014
|Apr 29, 2014
|Apr 30, 2014
|Apr 30, 2014
|Apr 30, 2014
|Apr 30, 2014
|Apr 30, 2014
|Apr 30, 2014
|Apr 30, 2014
|Apr 30, 2014
Keyboard shortcuts:
FForum PPrevious NNext WNext unread UUpvote SSubscribe RReply QQuote BBookmark MMy threads
Color scheme? Blue / Yellow
Latest reviews
Finished challenges
|Chicago Alley by tko
from Down the alleyway
|Callan-5680 by vbuhay
from What Child's Dream May Come
|Widget by Wilfried HKG
from Widget
|Oxbow Bend by stickpointed
from Landscape - Colour #2
Most popular cameras
In-depth testingLatest Camera ReviewsBeyond the studio testsFeature Articles and VideosPIX VideosTalks, demos and panels691The Canon that canCanon EOS 80D Review364Touchscreen street shooterFujifilm X70 Review2136Upwardly mobileSony a6300 Review325Power ZoomPanasonic Lumix ZS100/TZ100 Review2481Retro through-and-throughFujifilm X-Pro2 Review
Top threads in this forum
Most bookmarked in this forum
Top posters in this forum
Follow us
All content, design, and layout are Copyright © 1998 - 2016 Digital Photography Review All Rights Reserved. Reproduction in whole or part in any form or medium without specific written permission is prohibited.

subset: commoncrawl


text:
Latest News
Oracle will buy NetSuite for $12 billion
Google hardens the Linux kernel in Android
Is the national security incursion provoking would-be hackers?
CIO stalwart Gathercole retires from public service
Health insurers accused of exploiting billing data
Follow Us
Log In
Benchmark Awards
CXO Challenge
What's On
Log In
Remember me
Forgot password?
Don't have an account? Register now!
Benchmark Awards
CXO Challenge
What's On
Optus to handle NBN satellite operations
Multi-year deal secured.
Feb 3 2014 1:01AM
Student faces US copyright extradition
Granted bail, banned from web.
Jun 20 2011 6:49AM
Wrongfully accused awarded $31k over child pr0n
Police investigation caught innocent in its net.
Apr 5 2011 10:34AM
Anonymous takes aim at IT security firm
Leaks emails, defaces social networking accounts.
Feb 8 2011 12:47PM
Operation Payback strikes Portugal
Portuguese email leak.
Oct 21 2010 2:19PM
Toshiba claims quantum key breakthrough
Paves way for one-time pad encryption.
Apr 21 2010 5:59AM
Quantum cryptography takes a step forward
Continuous operation successfully tested.
Apr 20 2010 1:10PM
Cyberwar test shows US vulnerable to attack
Test highlights vulnerability of national networks.
Feb 18 2010 4:19PM
Anonymous blasts Government sites for second day
Titstorm still listed as "in progress".
Feb 11 2010 2:50PM
Climate email hack 'a professional job'
Blamed on government or lobbyists.
Feb 3 2010 6:46AM
China lays claim to world's largest piracy bust
The Chinese state government has issued prison sentences for what was believed to be the largest and most lucrative software piracy operation in the world.
Jan 5 2009 2:03PM
Microsoft shakes up online operation
Microsoft is reorganising its Platforms and Services Division as the head of the group prepares to depart.
Jul 28 2008 9:27AM
Italian officials arrest 26 in anti-phishing operation
Italian authorities have arrested 26 people from two criminal organizations for their involvement in a phishing scheme.
Jul 17 2007 9:40AM
Microsoft files suit against spyware operation
Microsoft announced today that it has filed a lawsuit against a spyware distributor, one day after the Federal Trade Commission (FTC) announced the company was shut down by a U.S. District Court judge.
Nov 14 2006 6:10PM
Verizon cuts off wireless spam operation
Verizon Wireless has won a permanent injunction to stop Passport Holidays of Ormond Beach, Fla., from sending unsolicited spam text messages to its mobile phone customers.
Feb 10 2006 10:18AM
Three indicted in connection with spam operation
A federal grand jury in Phoenix, Ariz. has indicted three people on charges of violating the federal Can-Spam Act for operating a pornographic spam business.
Aug 26 2005 4:30PM
Identity theft operation unearthed
Sunbelt Software researchers say they have uncovered what appears to be a massive online identity theft ring, which is under investigation by the FBI.
Aug 5 2005 7:29PM
Police suspended in Aust child porn operation
NSW Police has suspended two of its officers and seized their home computers, as part of an Australia-wide investigation into child pornography.
Oct 8 2004 12:00AM
Adelaide to score in EDS Operation Best Shore
Nov 21 2002 12:00AM
Most popular tech stories
Synnex roadshow fires up the Perth channel
10 hottest smartphones of 2016
Which IT leaders did we spot at Fujitsu World Tour 2016?
Kaspersky takes Sydney partners to Madame Tussauds
10 hottest products for SMBs
7 accounting packages for Australian small businesses compared: including MYOB, QuickBooks Online, Reckon, Xero
How long will a UPS keep your computers on if the lights go out?
How do I make sure my email is properly synced between all my computers?
Tip: Your shop can use a smartphone instead of an EFTPOS terminal
Do you use Dropbox? Here are some clever tricks
Top 25 fantasy games of all time
How to: How much RAM do you really need?
Head-to-Head: Synology DS216+ versus QNAP TS-251+ 2-bay NAS
Investigator: The NBN nightmare
Top 15 obscure video game consoles for collectors
PSA: You can play Red Dead Redemption on PC… kinda
Hands-on Preview: Mafia III goes south
Review: Nvidia GeForce GTX 1060 Founder's Edition
20 key tips for succeeding at Rainbow Six Siege
Hands-on Preview – Deus Ex: Mankind Divided's campaign is augmented to impress
Using Watson IoT to predict natural disasters
The four fundamentals of IoT value
Using LoRa to build a 'Fitbit for Sydney'
IoT network reaches 25 percent of A/NZ population
How IoT can create intelligent organisations
Log In
Don't have an account? Register now!
Remember me
Forgot your password?


text:
Your browser does not support iframes.
Sydney, North Shore & Northern Beaches, Temporary
26 Jul, 2016
Long term contracting opportunity supporting a large scale construction project. Immediate start, $40.00 per hour + Super
Job Category: Accounting
Sydney, Parramatta & Western Suburbs, Temporary
26 Jul, 2016
This multinational logistics organisation is in need of an experienced Credit Officer to join their team at their office in St Marys.
Sydney, South West & M5 Corridor, Temporary
26 Jul, 2016
Programmed are currently seeking Production Operators for a busy national company based in Ingleburn NSW. ONGOING!! APPLY NOW!!
Job Category: Manufacturing/Operations
Programmed are currently seeking experienced Machine Operators for a national company based in Wetherill Park NSW. ONGOING! APPLY NOW!
6 month contract to migrate a newly acquired business unit to Microsoft Dynamics Navision. Strong SQL Experience essential.
Job Category: I.T. & T
Sydney, CBD, Inner West & Eastern Suburbs, Temporary
26 Jul, 2016
Our client is providing a great temporary role that has the potential to go permanent!
Job Category: Call Centre & Customer Service
Sydney, All Sydney, Temporary
26 Jul, 2016
On offer are short and long temp assignments as well as temp to perm opportunties
Job Category: Insurance & Superannuation
, , Temporary
26 Jul, 2016
Leading organisation - Parking available onsite, Immediate Start - $26.24 + S per hour, 6-month contract with view to permanency
Bring your exposure to State/Fed govt and work in a client facing information officer role where you will be required to multi task


text:
Tom Petty Long After Dark (Remastered)
29 ratings
|$6.74 Limited Time Only
|You Save:
|$3.14 (32% Off)
Available: Usually ships in 1-3 business days
Format: CD
sku: 32S98
Brand New
CD Details
- Released: March 20, 2001
- Originally Released: 2001
- Label: MCA
Entertainment Reviews:
Q - 8/01, p.1543 stars out of 5 - "...The sound of water being expertly trodden...housing the exquisite 'You Got Lucky' and 'Finding Out'..."
CMJ - 1/5/04, p.12Ranked #20 in CMJ's "Top 20 Most-Played Albums of 1983".
Song previews provided courtesy of iTunes
Product Description:
Tom Petty & The Heartbreakers: Tom Petty (vocals, guitar); Benmont Tench (vocals, keyboards); Howe Epstein (vocals, bass); Stan Lynch (vocals, drums); Mike Campbell (guitar, organ).
Additional personnel: Ron Blair (bass); Phil Jones (percussion).
Recorded at Record Plant, Wally Heider's, and CA Crystal, Hollywood, California; Rumbo Studios, Canoga Park, California.
All tracks have been digitally remastered.
On his first four albums, Petty pulled off the impressive feat of starting out great and improving with each record. LONG AFTER DARK may not have extended that streak to five, but it came pretty damn close, and it's a solid, above-average offering that has more in common with the hard-rocking DAMN THE TORPEDOS than the more introspective, folk-tinged HARD PROMISES. Sonically, LONG AFTER DARK is flawless, it's the hardest Petty and company have ever rocked; Petty and Campbell's guitars would never sound this raw again (Petty had been listening to some AC/DC at the time, which obviously helped). Lyrically, the album is almost unrelentingly bleak, as Petty weaves tale after tale of hard luck and working men doomed to lives of tribulation. He's popmeister enough to keep it catchy, so you don't get bogged down by the weighty topics, and wise enough to disavow any Beautiful Loser claims ("I don't think pain is so romantic").
Tom PettyDamn The Torpedoes
View Details
$4.48 Super Savings
Tom PettyDamn The Torpedoes [Deluxe Ed.] (2-CD)
View Details
$26.96 Super Savings
Tom PettyEcho
View Details
$9.22 Super Savings
Tom PettyHard Promises (Remastered)
View Details
$6.74 Super Savings
Tom PettyHighway Companion
View Details
Tom PettyInto The Great Wide Open
View Details
$6.74 Super Savings
Tom PettyThe Last DJ
View Details
Tom PettyLet Me Up (I've Had Enough)
View Details
$5.97 on SALE
Tom PettyThe Live Anthology (4-CD Box Set)
View Details
$22.03 Super Savings
Tom PettyMojo
View Details
Home Alone Christmas (CD)
View Details(15)
Saturday Night Live - Lost & Found: SNL in the 80s (DVD)
$4.98 on SALE
View Details(9)
Let Me Up (I've Had Enough) (CD)
$5.97 on SALE
View Details(28)
Greatest Hits (CD)
$9.72 Super Savings
View Details(215)
The Postman (DVD)
$8.34 Super Savings
View Details(307)
Mojo (2-LPs-180GV)
View Details(192)
Damn The Torpedoes (CD)
$4.48 Super Savings
View Details(57)
Tom Petty & The Heartbreakers (CD)
$4.81 Super Savings
View Details(33)
Music Lovers' Ratings & Reviews:
Customer Rating:
Based on 29 ratings.
Based on 29 ratings.
Be the first Music Lover to write an online review of this product!
Similar Products:
Music Categories:
Product Groupings:
Product Info:
- Sales Rank: 88,688
- Shipping Weight: 0.25/lbs (approx)
- International Shipping: 1 item
Not Now! (CD)
View Details
$13.10 Super Savings
Bryan Adams (CD)
$11.12 Super Savings
View Details(13)
Icon (CD)
$7.09 Super Savings
View Details(7)
Live! Live! Live! (CD)
$6.74 Super Savings
View Details(19)
Reckless (CD)
$9.72 Super Savings
View Details(67)
Gold (2-CD)
$9.72 Super Savings
View Details(10)
Peakin' At The Beacon (CD)
View Details(40)
History of Rock (10-CD Set)
$19.98 on SALE
View Details(6)
Summer Hits: 47-Song Collection (3-CD)
$8.98 on SALE
View Details(2)
Acoustic: Guaranteed No Hiss (DVD)
99¢ on SALE
View Details(22)
WJMK 104.3 - Great Ladies of Rock & Roll - The 60s (CD)
$2.98 on SALE
View Details(15)
History of Rock - JukeBox Giants, Volume 2 (CD)
$2.98 on SALE
View Details(11)
Summer Fun: 43-Song Collection (3-CD)
View Details
$8.98 on SALE
WCBS FM101.1 - Great Ladies of Rock & Roll - The 70s (CD)
$2.98 on SALE
View Details(5)
History of Rock - For Lovers Only, Volume 4 (CD)
$2.98 on SALE
View Details(11)
Top ranking CD:
- Burl Ives The Best of Little Bitty Tear (CD) ~ $2.98 on SALE
- Johnny Cash Original Golden Hits, Volumes 1 & 2 (CD) ~ $2.98 on SALE
- Various Artists History of Rock - JukeBox Giants, Volume 1 (CD) ~ $2.98 on SALE
- Various Artists Country Top Hits of the 50s, 60s, 70s and 80s (4-CD) ~ $19.98 on SALE
Jan & Dean Greatest Hits (CD) ~
$5.35 Super Savings


text:
The regions where you're most likely to miss out on surgery
The Government's latest figures provide detailed picture of who's missing out on surgery and why.
Where do capital's mayoral candidates stand on a Wellington-Porirua merger?
Wellington's mayoral candidates have revealed where they stand on a council merger with Porirua.
Maori needed at top levels of Corrections to reduce reoffending
An adviser to the the Department of Corrections says Maori aren't present in decision-making roles.
Every student to get a 'personalised career plan' under a Labour Government
A Labour Government would spend $30 million to "professionalise careers advice'' in schools.
Weird coincidence: Andrew Little gets dodgy chair on Breakfast - again
Andrew Little's TV seat gets the wobbles - and not for the first time.
National MP Maurice Williamson to retire at election
From big gay rainbows, to leaky homes success and a major breach of the Cabinet Manual. Maurice Williamson bows out.
Predator-free New Zealand 'unrealistic' - NZ First
John Key has a plan to rid the country of pests - is it ambitious or unachievable?
Government sets target to make New Zealand 'predator-free' by 2050
The government is planning to eradicate the country of all pests threatening native birds by 2050.
McClay rebuked by PM after failing to reveal wider fears of China retribution
John Key has publicly reprimanded Trade Minister Todd McClay after he downplayed China trade retaliation fears.
Councils call for a return to the days when we were paid to recycle
Councils urge Government to adopt national cash-for-bottles scheme.
John Key wants to put the brakes on Kevin Rudd in UN race
John Key says even Australians know which former PM should get the UN top job.
Labour MP Trevor Mallard vacates Hutt South electorate to apply for Speaker position
He says he wants Speaker's job, but John Key says he's "waving the white flag".
Faces of Innocents: CYF facing 'unfunded cost pressures' of millions, Government admits
The agency charged with protecting vulnerable children is short of the cash it says it needs to meet increased demand.
Corrections failing Maori, needs drastic culture change - claim
A retired probation officer says Corrections needs a dramatic culture change to reduce Maori reoffending.
John Key: Don't write Helen Clark off yet, after UN polling
John Key says UN security council members are wrong to vote "tactically" against Helen Clark.
Labour leader Andrew Little's New Plymouth billboard defaced by vandals
The new face of the Labour Party leadership is small, furry and named Stuart.
Nick Smith reveals he gargled paint stripper as mouthwash
If an accidental poisoning can happen to a minister, it can happen to toddlers, Nick Smith says.
Reserve Bank mandate no longer cutting it - Labour
The Reserve Bank needs the ability to focus on more than just inflation, says Labour.
Foreign Minister Murray McCully contracted Zika
Foreign Minister Murray McCully was infected by the Zika before it became a global health concern.
Veteran Taranaki regional councillor will not contest seat in upcoming election
"Being able to bring farmers' concerns to the table and understand how council decisions affect them is extremely important."
PM's department warned of Chinese trade threats, but didn't brief him
It was told about the reprisals over China's steel stoush, but didn't tell him.
Legal cannabis could collect $150 million a year but Bill English isn't pursuing it
It could bring in a $150 million windfall in tax revenue. So why is the Government not interested?
Failed leadership coup exposes more 'toxic culture' at Wellington City Council
Electioneering set to get ugly as failed council coup reveals rifts in capital.
Tracy Watkins: Helen Clark's down but not out in the race to lead the UN
OPINION: Helen Clark's staying mum on her next move in the race to lead the UN, but things just got a lot harder.
Patrick Gower admits man crush on Donald Trump's son in weird live video from RNC
The TV political editor delivers a part news report, part travel diary, part stand-up skit from the Republican convention in the US.
Helen Kelly: 'My back is broken and I only have months to live but I'm pain free'
Helen Kelly has a broken back after tumours pushed through her spinal cord. She says cannabis is helping her cope with the pain.
US Vice President Joe Biden accepts challenge at Government House
US Vice President Joe Biden didn't miss a beat during a powhiri at Government House this week.
Prime Minister John Key visits South Canterbury
Prime Minister John Key has made a whirlwind visit to South Canterbury.
Kermadec ocean sanctuary gets the go-ahead from committee
Tweak the name, make a few adjustments, and continue on, the Environment Minister is told.
Number of Kiwis with severe social housing needs rises on Social Housing Register
The number of people coming to the govt with severe housing needs has increased.
Stacey Kirk: Is New Zealand's mental health service doing more harm than good?
OPINION: Locking someone up for 23 hours in a day can only make their mental illness worse.
US ship visit standoff all over bar the screening - but what about China?
OPINION: The three-decade-long self-imposed freeze on United States ship visits has been declared over.
RNC is like 'politics on speed' say New Zealand MPs
New Zealand MPs at the event say divisions in the party have made for an electric atmosphere.
NZ steel bid 'courageous', says US steel workers' union
American steel workers are throwing their support behind New Zealand's industry.
Below the beltway: The week in politics
OPINION: Who's up and who's down in the week of politics?
NZ First leader Winston Peters calls for Finance Minister Bill English to resign
"That country drawl is no longer cutting it" - Winston Peters rips into Bill English over housing.
Helen Clark lags as Security Council holds first ballot to choose next UN Secretary General
There are claims the "old boys network" has nobbled Helen Clark in a shock result in the first vote for the UN's top job.
US naval ship visit a 'victory' for anti-nuclear campaigners
Prominent anti-nuclear activists are celebrating the end of a 30-year stand off with the United States over ship visits.
Helen Clark to go through first UN Security Council vote
The Security Council will endorse who they think should be the next UN secretary-general.
Kiwi farmers face more difficult years according to OECD - Labour
Dairy farmers face three more years of pain if OECD forecasts are right, warns Labour.
US Vice-President Joe Biden signals end to 30 year cold shoulder over ship visits
US Vice-President Joe Biden formally accepts invite to send naval vessel to NZ later this year.
US Vice-President Joe Biden hangs with All Blacks
"I don't mean to offend any of you," said the US Veep. "But this is the reason I came."
NZ was the 'mouse that roared' on foreign policy but now it's 'mute' on China - Peter Dunne
Peter Dunne says the Ministry of Foreign Affairs' fear of upsetting China is "downright humiliating".
Greens would set up Minister for Manufacturing within MBIE, if in Government
Racing has a minister so why shouldn't manufacturing, say the Greens.
David Cameron's sad exit: Turns up in jeans and t-shirt to meet John Key
John Key reveals Britain's former PM David Cameron had no time to dress up for their appointment.
Interest rate cuts "likely" as the Reserve Bank warns dollar needs to drop
Reserve Bank says low inflation is likely to prompt it to cut the cost of borrowing.
United States naval ship to visit New Zealand
The US is expected to send a military vessel into NZ waters, ending a 30-year standoff.
Naval ship visit restores common sense to NZ-US relations
OPINION: Times have moved on. In an increasingly uncertain world, polls show overwhelming support for US ship visits.
There's a bigger game than steel dumping at play in China trade stoush
OPINION: Reprisals against New Zealand's key exports by China are about as serious as a trade dispute could get.
Explosive resignation email exposes Wellington City Council's 'toxic culture'
Cycleway adviser's resignation email blasts council engagement as worse than Kazakhstan's.
Most popular
Unison Networks defends price hike for consumers with solar panels
Super Black Racing Supercars boss Tony Lentino dies aged 42
A 'fine creation' worth hundreds of millions brought low by family dissent
MBIE investigates exploitation of backpacker labour in beds for wages deals
Special offers
Opinion poll
Where do you stand on political coat-tail riding?Related story: Voters reject riding on the coat-tails


text:
|Home | About | Journals | Submit | Contact Us | Français
Individuals with body dysmorphic disorder may have perceptual distortions for their appearance. Previous studies suggest imbalances in detailed relative to configural/holistic visual processing when viewing faces. No study has investigated the neural correlates of processing non-symptom-related stimuli. The objective of this study was to determine whether individuals with body dysmorphic disorder have abnormal patterns of brain activation when viewing non-face/non-body object stimuli.
Fourteen medication-free participants with DSM-IV body dysmorphic disorder and 14 healthy controls participated. We performed functional magnetic resonance imaging while participants matched photographs of houses that were unaltered, contained only high spatial frequency (high detail) information, or only low spatial frequency (low detail) information. The primary outcome was group differences in blood oxygen level-dependent signal changes.
The body dysmorphic disorder group showed lesser activity in the parahippocampal gyrus, lingual gyrus, and precuneus for low spatial frequency images. There were greater activations in medial prefrontal regions for high spatial frequency images, although no significant differences when compared to a low-level baseline. Greater symptom severity was associated with lesser activity in dorsal occipital cortex and ventrolateral prefrontal cortex for normal and high spatial frequency images.
Individuals with body dysmorphic disorder have abnormal brain activation patterns when viewing objects. Hypoactivity in visual association areas for configural and holistic (low detail) elements and abnormal allocation of prefrontal systems for details is consistent with a model of imbalances in global vs. local processing. This may occur not only for appearance but also for general stimuli unrelated to their symptoms.
Body dysmorphic disorder (BDD) is a psychiatric disorder in which individuals are preoccupied with perceived defects of their appearance or are excessively concerned about a slight physical abnormality, which causes distress and/or functional impairment(American Psychiatric Association., 2000). Perceived defects can involve any body area but most often involve the face or head(Phillips et al., 1993). Individuals experience obsessive thoughts about their appearance and tend to engage in repetitive, time-consuming behaviors such as checking their appearance in the mirror and scrutinizing details of others' appearances to compare to their own(Phillips, 2005). BDD is estimated to affect approximately 0.7-2.4% of the population(Buhlmann et al., 2010, Faravelli et al., 1997, Koran et al., 2008, Otto et al., 2001, Rief et al., 2006), and is associated with high lifetime rates of psychiatric hospitalization (48%)(Phillips and Diaz, 1997) and suicide attempts (22-27.5%)(Phillips et al., 2005a, Phillips and Diaz, 1997, Veale et al., 1996). Very few have good insight and 36-60% are delusional(Gunstad and Phillips, 2003, Mancuso et al., 2010, Phillips et al., 2005b). Despite the prevalence and severity of the disorder, relatively little is known about the pathophysiology underlying various symptom domains.
One potentially important clinical symptom domain in BDD is distorted perception of appearance; they perceive certain features to be defective(American Psychiatric Association., 2000), e.g. their nose is crooked or their skin is pockmarked, contrary to what others perceive of them. In most cases, they seem to excessively focus on details of their appearance at the expense of global or configural aspects(Phillips, 2005). A possible explanation of these misperceptions might lie in visual perceptual abnormalities.
Neuropsychological and brain imaging studies suggest that abnormal information processing may contribute to perceptual abnormalities in BDD(Deckersbach et al., 2000, Feusner et al., 2010, Feusner et al., 2007b, Yaryura-Tobias et al., 2002). Early evidence of abnormalities in own-face processing comes from a study in which individuals with BDD perceived distortions of a digital photograph of their face, which were not actually present(Yaryura-Tobias et al., 2002). Additional evidence of abnormal visual processing of own faces comes from a functional magnetic resonance imaging (fMRI) study, which demonstrated hyperactivity in fronto-striatal systems for unaltered images and hypoactivity in visual cortical systems for low spatial frequency information that conveys holistic and configural elements(Feusner et al., 2010). Another fMRI study using others' faces demonstrated left hemisphere hyperactivity relative to healthy controls in higher-order visual processing regions, suggesting predominant detailed and analytic processing(Feusner et al., 2007b). These studies suggest abnormalities in visual processing in BDD, at least for symptom-relevant stimuli of own and others' faces.
Aside from abnormalities of face processing, whether individuals with BDD experience general abnormalities in visual processing is not yet clear. Early evidence that this may be the case comes from a study using the Rey-Osterrieth Complex Figure Test (RCFT) to compare visuospatial performance of individuals with BDD relative to healthy controls(Deckersbach et al., 2000). The BDD cohort demonstrated selective recall of details rather than larger organizational design features. This search strategy may implicate a deficit in executive functioning mediated by frontal-striatal circuits or other higher-order perceptual processing systems. Alternatively, deficits may have resulted from encoding an initially distorted lower-order visual perception, or from aberrant retrieval and reconstruction. In an earlier study Hanes et al. (1998) did not find abnormal performance on the RCFT in individuals with BDD relative to healthy controls(Hanes, 1998). Thus, it remains unclear if individuals with BDD demonstrate abnormal visual processing of objects or figures and if so, what systems may mediate this. No study to date has investigated the neural correlates of visual processing of non-face/non-body objects in individuals with BDD.
The objective of the current fMRI study was to test if individuals with BDD have abnormal visual processing for stimuli unrelated to their symptoms, i.e. non-face/non-body objects. We used houses as the object stimuli because they contain a combination of holistic (entire house as one precept), configural (e.g. spatial relationships between windows and roof) and detailed (e.g. shingles) information from which to understand different elements of visual processing. In addition, multiple previous studies have examined object processing in healthy controls using houses as stimuli, providing a framework of expected networks that includes the parahippocampal place area, fusiform gyrus, lateral occipital cortex, cuneus, and lingual gyrus(Epstein et al., 1999, Ewbank et al., 2005, Pourtois et al., 2005).
We used digital photographs of houses that were either unaltered or altered to contain only high spatial frequency (HSF) or only low spatial frequency (LSF) information. Detailed visual analysis relies on fine visual resolution, which is conveyed by HSF information(Norman and Ehrlich, 1987, Schyns and Oliva, 1999). Configural and holistic elements are primarily conveyed by LSF information(Costen et al., 1996, Sergent, 1985). We therefore used HSF, LSF, and normal spatial frequency (NSF) houses to functionally dissect visual processing systems. Our hypothesis was that individuals with BDD would demonstrate abnormalities for processing houses, similar in nature to that observed in the previous other-face study and therefore possibly representing a general underlying abnormal visual processing phenotype. Specifically, we hypothesized that the BDD group would demonstrate greater left-hemisphere activity in secondary and higher-order occipital and temporal object- and house-processing regions, such as the cuneus, lingual gyrus, fusiform gyrus, and parahippocampal place area. Based on what was observed for others' faces, we predicted the greatest degree of abnormalities for LSF images, followed by NSF images, and no difference from controls for HSF images. Based on what was observed for others' and own faces, we predicted that greater symptom severity would be associated with lesser activity in the dorsal visual stream for LSF images.
The UCLA Institutional Review Board approved the protocol for the study. Fourteen participants with BDD and 14 healthy controls, ages 20 to 48, provided informed consent. (All participants had participated in the previous own-face BDD fMRI study(Feusner et al., 2010)). BDD participants and controls were recruited from the community and were of equivalent gender, age, and level of education. All were right-handed, as determined by the Edinburgh Handedness Inventory(Oldfield, 1971). BDD participants met DSM-IV criteria for Body Dysmorphic Disorder, diagnosed by the first author (JDF), who has clinical expertise with this population. Diagnoses were made using the Body Dysmorphic Disorder Module(Phillips et al., 1995), a reliable diagnostic module modeled after the Structured Clinical Interview for DSM. In addition, we performed a clinical psychiatric evaluation and screened all participants with the Mini International Neuropsychiatric Inventory (MINI)(Sheehan et al., 1998). All BDD participants were required to have a score of ≥20 on the BDD version of the Yale-Brown Obsessive-Compulsive Disorder Scale (BDD-YBOCS)(Phillips et al., 1997). The BDD-YBOCS is a validated scale that is a widely-used standard to evaluate symptom severity in BDD, with a range of scores from 0 to 48 (Phillips et al., 1997). It has excellent interrater and test-retest reliability (intra-class correlation coefficients for total score=0.99 and 0.88, respectively), internal consistency (Cronbach's alpha=0.80), and convergent validity (r=.55 with the CGI) (Phillips et al., 1997). In addition to the BDD-YBOCS, we also administered the Hamilton Depression Rating Scale-17 (range of scores from 0 to 54) (Hamilton, 1960) and the Hamilton Anxiety Rating Scale (range of scores from 0 to 56) (Hamilton, 1969), which have similar standards for validity and reliability. These were included to provide a broader understanding of clinical severity of participants. We allowed participants with delusional beliefs about their appearance (score of 4 on item 11 of the BDD-YBOCS: "Lacks insight, delusional").
Exclusion criteria for all participants included: substance abuse or dependence within the past 12 months, lifetime neurological disorder, pregnancy, or any current medical disorder that may affect cerebral metabolism. We excluded BDD participants with other Axis I disorders (current or past bipolar disorder, current or past panic disorder, current social phobia, current obsessive-compulsive disorder, current posttraumatic stress disorder, current or past psychotic disorders, current anorexia nervosa, or current bulimia nervosa). We did not exclude those with comorbid dysthymia, major depressive disorder, or generalized anxiety disorder; as depression and anxiety are so frequently comorbid in this population, we believed it would not be a representative sample to exclude these. However, we required that BDD be the primary diagnosis as defined by the MINI ("Which problem troubles you the most or dominates the others or came first in the natural history?"). We excluded any participants whom the investigator judged were suicidal. Healthy controls could not have any current or past Axis I disorder, as determined by the MINI.
BDD participants were free from psychoactive medications for at least 8 weeks prior to the study and were not receiving cognitive-behavioral therapy. Healthy controls were excluded if they were taking any psychiatric medication or were in any psychotherapy treatment. We only included participants with normal or corrected vision, as verified by Snellen eye chart. Any participants with ferromagnetic metal implantations or devices or weight greater than 280 lbs were excluded due to safety and capacity requirements of the MRI scanner.
We obtained digitized, frontal view photographs of houses from the Internet and used Adobe Photoshop® CS3 software to convert to grayscale. We created HSF and LSF images, as previously described(Feusner et al., 2007b). This included using Scion Imaging Software (http://www.scioncorp.com) to Fourier-transform digital photographs, alter these images in their frequency domains, and then reverse Fourier-transform them to create high-pass and low-pass filtered images(Iidaka et al., 2004). A "high-pass filter" creates images that contain only the HSF information. A "low-pass filter" creates images that contain only LSF information. We normalized luminosity across stimuli (Fig. 1).
Three different categories of houses comprised the tasks: A) NSF, B) HSF, or C) LSF. The control condition consisted of gray rectangle and square shapes, approximately the same size as the houses. We used MacStim 3.0 (White Ant Occasional Publishing, West Melbourne, Australia) to program the stimuli presentation and to record accuracy and reaction time. The matching task is a forced-choice, two alternative task. Each set of stimuli consisted of three houses or shapes: a target house or shape on top and two selection houses or shapes on the bottom. We instructed participants to: "Choose the house or shape on the bottom that is the same house or shape as the one on the top, by pressing the right or left button. Make your selection as rapidly and as accurately as possible." Each set of houses or shapes appeared on the screen for 4 seconds (sufficient time to allow for visual inspection and for the task to be easy, yet short enough to likely minimize habituation of BOLD response), with a 1-second interstimulus interval.
Each block consisted of 4 sets of unique houses of the same spatial frequency that were A) NSF, B) HSF, or C) LSF; or 4 sets of the control task. Each set of 4 blocks (A-B-C-Control) was repeated four times in each run. The total time for each run was 6 minutes, 8 seconds. There were two runs, the second presented in a different order. Between participants, differently ordered runs were counter-balanced using a Latin Square design, to avoid possible order effects. Participants wore fMRI-compatible goggles to view the stimuli. If participants wore eyeglasses, appropriate corrective lenses for the goggles were used. After each run, participants rated their anxiety level during the tasks on a Likert-scale of 0-10.
We used a 3-Tesla Allegra (Siemens) MRI scanner to evaluate BOLD contrast, using T2*-weighted echo planar imaging (EPI) gradient-echo pulse sequence (TR = 2.5 seconds, TE = 35 milliseconds, Flip-Angle = 90°, Matrix = 64×64, field-of-view = 24×24 cm, in-plane voxel size 3.1 mm × 3.1 mm, slice thickness 3mm, 1mm intervening spaces, and 28 total slices). We obtained matched-bandwidth T2 as well as MP-RAGE T1-weighted images to provide detailed anatomy during structural image acquisition.
Image processing included motion correction, skull stripping, spatial smoothing of 5mm full-width/half-maximum Gaussian kernel, mean-based intensity normalization of all volumes by the same factor, and high-pass temporal filtering. We co-registered functional images of each participant to corresponding matched-bandwidth structural images in native space, then performed a second-stage registration to their higher-resolution MP-RAGE scans, and finally registered these to structural standard images, defined by the Montreal Neurological Institute averaged 152 standard brain.
We performed a two-way repeated-measures analysis of variance to compare response times (RT) and accuracy rates between groups, using PROC GLM in SAS®. Group (BDD and healthy controls) was the between-subject factor and stimulus type (NSF, HSF, LSF, and control stimuli) was the within- factor.
A two-sample t-test was used to compare mean subjective anxiety scores between groups.
We used FEAT software (FMRI Expert Analysis Tool) Version 5.4, part of the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain Software Library (FSL), www.fmrib.ox.ac.uk/fsl.
For within-group analyses, we performed a random-effects analysis with subject as the random factor to identify typical patterns of brain activity in BDD participants and healthy controls. We modeled the hemodynamic response function by performing a simple convolution of the blocked experimental paradigms of each condition vs. control task with the canonical hemodynamic response function and its temporal derivative(Aguirre et al., 1998). To determine the patterns of activations in the BDD group and in the control group, we analyzed the normalized data with multiple regression by using three regressors to model hemodynamic changes associated with the HSF, LSF, and NSF tasks, each contrasted to the control task.
Model fitting generated whole brain images in native space of parameter estimates and corresponding variance, representing average signal change during each particular contrast. We used FMRIB's Improved Linear Model (FILM) for time-series statistical analysis, using local autocorrelation correction(Woolrich et al., 2001). We thresholded Z statistic images using clusters determined by Z>2.0 and a (corrected) cluster significance threshold of P=0.05(Worsley et al., 1992).
For between-group analyses, we directly compared BDD participants and controls using a voxel-wise, mixed-effects analysis in FSL. After we performed within-groups analyses, we used FLAME (FMRIB's Local Analysis of Mixed Effects) stages 1 and 2(Beckmann et al., 2003, Woolrich et al., 2004). We thresholded Z statistic images using clusters determined by Z>2.0, and a (corrected) cluster significance threshold of P=0.05(Worsley et al., 1992). A two-sample t-test identified group mean differences in activity at each voxel.
To graphically represent BOLD signal changes in regions identified from the voxelwise analysis as differentially active between groups, we performed post hoc percent signal change analyses. For this we created a set of spherical ROIs (6 mm radii) at local maxima for significant clusters from the between-group analyses. Parameter estimate data were then extracted from each ROI for each participant using FSL command line tools(Poldrack, 2007).
To investigate the relationship between symptom severity in BDD participants and regional brain activation, we entered results from the within-group analysis into a higher-level analysis with de-meaned BDD-YBOCS scores as a covariate of interest. This produced a voxelwise map of regions whose activity correlated with BDD symptom severity. We also extracted post hoc percent signal change from local maxima (as above) to create scatterplots depicting the relationship between symptom severity and brain activity across BDD participants.
Table 1 summarizes demographic and psychometric data. One BDD participant had comorbid major depressive disorder, one had generalized anxiety disorder, four had major depressive disorder and generalized anxiety disorder, and one had both dysthymic disorder and generalized anxiety disorder. All participants had preoccupations with perceived facial defects.
The BDD group had slower mean RT across all tasks including the control task (1.28±0.22 sec. vs. 1.03±0.35 sec. for NSF, 1.26±0.22 sec. vs. 0.99±0.37 sec. for LSF, 1.65±0.33 sec. vs. 1.39±0.47 sec. for HSF, and 1.22±0.23 sec. vs. 0.96±0.30 sec. for control stimuli, for BDD and healthy control groups, respectively). There were significant main effects of group (F1,26 = 5.14, P=0.0320) (slower RT for the BDD group) and stimulus (F3,78 = 79.41, P<0.0001) (slower RT for HSF images) but no group by stimulus interaction effect (F3,78 = 0.02, P=0.996).
Mean accuracy rates were similar between groups across all stimuli (99.33±1.81% vs. 99.09±1.50% for NSF, 99.33±1.33% vs.98.42±2.07% for LSF, 98.73±1.55% vs. 98.88±1.56% for HSF, and 96.91±2.88% vs. 96.36±3.93% for control stimuli, for BDD and healthy control groups, respectively). There was a significant main effect of stimulus (F3,78 = 8.02, P=<0.0001), (lower accuracy for control stimuli) but no significant main effects of group (F1,26 = 0.77, P=0.389) or group by stimulus interaction (F3,78 = 0.29, P=0.829). In the BDD group, correlations were nonsignificant between RT (collapsed across all stimuli because of absence of a group by stimulus interaction effect) and BDD-YBOCS scores (r=0.34, P=0.24), HDRS scores (r=0.29, P=0.31), HARS scores (r=0.16, P=0.60), and task anxiety (r=-0.14, P=0.62).
Mean anxiety during the experiment was slightly higher for the BDD than the healthy control group, but not significantly different (3.32±2.45 vs. 2.04±1.88, t=1.55, d.f.=26, P=0.13). We explored using task anxiety as a covariate in the two-way repeated measures ANOVA. When controlling for anxiety, there were still significant main effects of group (F1,25 = 5.88, P=0.0229) (slower RT for the BDD group) and stimulus (F3,75 = 29.86, P<0.0001) (slower RT for HSF images) but no group by stimulus interaction effect (F3,75 = 0.05, P=0.977) for RT. For accuracy rate, when controlling for anxiety there was a significant main effect of stimulus (F3,75 = 4.83, P=<0.0119) (lower accuracy for control stimuli), but no significant main effects of group (F1,25 = 0.59, P=0.451) or group by stimulus interaction (F3,75 = 0.62, P=0.543).
For all stimulus types, the BDD and healthy control groups activated extensive bilateral visual cortex, as well as fusiform cortex and parahippocampal gyri. There was also activation for both groups for NSF and HSF (but not LSF) images evident in subcortical (thalamic) and prefrontal (paracingulate, supplementary motor area, and inferior frontal gyrus) regions. For HSF images, activation in bilateral frontal poles was evident for the BDD but not healthy control group.
There were no significant differences between groups for NSF stimuli.
For the LSF images, the BDD group relative to the healthy control group showed lesser activity in the left parahippocampal cortex, the left hippocampus, left lingual gyrus, left posterior cingulate, and bilateral precuneus (Fig. 2a, Table 2). This was accounted for primarily by lesser activation in the BDD group relative to healthy controls in these regions (see percent signal changes – Fig. 2b).
For HSF images, BDD participants relative to controls showed greater activity in bilateral frontal pole, left superior frontal gyrus, right anterior cingulate gyrus, and right paracingulate gyrus (Fig. 2a, Table 2). This was accounted for by activation in the BDD group relative to the control task and deactivation in healthy controls relative to the control task in these regions (see percent signal changes – Fig. 2b). To verify if this pattern represented deactivation in healthy controls and activation for the BDD group for the HSF task vs. "true" baseline (as opposed to HSF vs. control task) we performed a post hoc analysis contrasting the HSF task as well as the control task to the rest periods of the scan (during which participants viewed a small crosshair in the middle of the screen). Within-groups results revealed deactivation in the healthy controls for both HSF and control tasks in bilateral dorsal and ventral medial prefrontal cortex, precuneus/posterior cingulate, and angular gyrus. The BDD group demonstrated similar deactivations in these regions for both HSF vs. baseline and control task vs. baseline, except for dorsal medial prefrontal cortex (see Fig. 5 in supplemental material online). There were no significant differences between groups for HSF vs. baseline or for the control task vs. baseline.
Due to the fact that there were behavioral differences between groups in response times on all tasks, we performed a between-groups analysis using response time on the tasks as a covariate of non-interest. For the LSF analysis, there were no significant differences between groups at a threshold of Z>2.0, but at Z>1.9 there was relative hypoactivation in the BDD group in the left lingual gyrus, the left parahippocampal gyrus, the left hippocampus, and the left precuneus (similar to the regional activation without RT as a covariate). For the HSF analysis, the regional activation was essentially unchanged in the prefrontal regions compared to results without RT as a covariate. For the NSF analysis, there remained no significant differences between groups.
For NSF images, there were inverse associations between BDD-YBOCS scores and activity in bilateral middle frontal gyrus, right lateral dorsal occipital cortex, bilateral orbitofrontal cortex, left anterior cingulate gyrus, left precentral gyrus, and left inferior frontal gyrus (See Fig. 3a; see also Fig. 4 and Table 3 in supplemental online material).
For LSF images, there were no significant associations between BDD-YBOCS scores and brain activity.
For HSF images, there were inverse associations between BDD-YBOCS scores and activity in left lateral occipital cortex, bilateral occipital pole, right dorsal cuneus, left inferior frontal gyrus, and left frontal pole. (See Fig. 3b; see also Fig. 4 and Table 3 in supplemental online material).
There were no significant positive associations between BDD-YBOCS scores and brain activity for any image type.
This study demonstrates that unmedicated individuals with BDD have abnormal brain activation patterns when viewing non-face/non-body objects. The primary finding is less activation than healthy controls in secondary visual processing systems for configural and holistic elements. Moreover, greater BDD symptom severity is associated with lesser activity in the dorsal visual stream and in ventrolateral prefrontal regions. Because images of houses are not symptom-related stimuli, the current study therefore suggests the possibility of general, aberrant visual processing in BDD.
These results confirmed our hypothesis of abnormal activity for LSF information in occipital and temporal visual processing systems in individuals with BDD. Contrary to our predictions, however, a pattern of predominant left hemisphere hyperactivity was not evident; instead, there was abnormal hypoactivity in left lingual gyrus and parahippocampal cortex. The parahippocampal cortex (in addition to a distributed network in bilateral ventral temporal and occipital cortex(Ishai et al., 2000, Ishai et al., 1999)) has been identified as an important region for recognition and encoding of places, scenes, and houses, and has been termed the "parahippocampal place area"(Epstein et al., 1999, Ewbank et al., 2005, Pourtois et al., 2009). The BDD group also demonstrated relative hypoactivation for LSF information in systems involved in directed and sustained attention including the posterior cingulate and precuneus(Cabeza and Nyberg, 2000, Cavanna and Trimble, 2006). Together, these findings provide evidence that individuals with BDD may under-activate systems involved in secondary visual processing and attention, specifically for configural and holistic visual elements.
The nature of these findings fit with results from a previous neuropsychological study of complex figure processing using the RCFT, in which individuals with BDD appeared to underutilize configural and holistic elements while selectively recalling and reproducing visual details(Deckersbach et al., 2000). It also fits with clinical observation that they often focus on details of their appearance, for example small skin blemishes or small asymmetries of their nose, at the expense of global or configural aspects.
For HSF information, there were differences in patterns of brain activation between groups. However, the post hoc between-groups analysis of the HSF task relative to a low-level baseline (as opposed to the matching task of circles and ovals) revealed that there were no significant differences. The within-groups post hoc analysis demonstrates that the overall pattern of deactivation in both groups appears to represent task-related deactivation in the default mode network (DMN); this includes medial prefrontal cortex, precuneus/posterior cingulate and inferior parietal lobule. Deactivation of the DMN is commonly observed in a wide variety of cognitive tasks, and activation is evident during rest (see (Buckner et al., 2008) for review). The within-groups analysis in this study suggests that there may have been lesser deactivation in dorsal medial prefrontal regions in the BDD group. Thus, it is possible that the BDD group may be somewhat less able to deactivate specifically the dorsal medial prefrontal portions of the DMN when engaging in the task. Since a subsystem of the DMN involving the dorsal medial prefrontal cortex is thought to be involved in self-referential thinking(Castelli et al., 2000, Gusnard et al., 2001) one speculation about these findings is that the BDD group may have difficulty in switching out of self-referential thinking during the task, perhaps related to intrusive thoughts about themselves or other spontaneous stimulus-independent thoughts(Andrews-Hanna et al., 2010, McGuire et al., 1996).
Greater BDD symptom severity was associated with lesser activity in the dorsal occipital cortex for HSF and NSF images, although not for LSF images, as hypothesized. Dorsal occipital cortex and parieto-occipital regions, part of the dorsal visual stream(Ungerleider and Mishkin, 1982), are involved in motion perception and extracting shapes and three-dimensional cues from objects(Durand et al., 2007, Peuskens et al., 2004, Sereno et al., 2002). Such information extracted from objects is then integrated with information related to object identification and recognition extracted via the ventral visual stream (see Farivar, 2009 for review(Farivar, 2009)). Therefore, greater BDD symptom severity may be associated with abnormalities in extracting configural visual information within unaltered and HSF images related to shape.
Greater BDD symptom severity was also associated with lesser activity in ventrolateral prefrontal regions. Previous studies have found that the ventrolateral prefrontal cortex (and to a lesser extent dorsolateral prefrontal cortex) is important for selection, comparison, and judgment, as evidenced by involvement in simultaneous matching tasks(Corbetta et al., 1991, Grady et al., 1996, Haxby et al., 1994, Kosslyn et al., 1994, McIntosh et al., 1996, Rushworth et al., 1997), and on tasks involving working memory and short and long-term memory(Haxby et al., 1995, Petrides, 1996, Rushworth et al., 1997). These are regions that are involved in face, form, color, and spatial matching(Corbetta et al., 1991, Grady et al., 1996, Haxby et al., 1994, Kosslyn et al., 1994) and have connections to visual processing regions in the temporal and occipital lobes (Catani et al., 2002, Webster et al., 1994). A possible interpretation of the results, then, is that greater severity of BDD symptoms may be associated with impaired integration of visual and prefrontal systems.
As this is the first functional neuroimaging study to investigate object processing in BDD, other similar studies are not available for comparison. However, other fMRI studies of other-face processing(Feusner et al., 2007b) and own-face processing(Feusner et al., 2010) have demonstrated both similar and different patterns. For example, in the own-face processing study, the BDD group had similar relative visual cortical hypoactivity in left primary and secondary visual processing regions for LSF images as in this study, although in posterior and inferior regions of the occipital cortex(Feusner et al., 2010). In contrast to the findings in this study, there were no significant differences from controls for HSF stimuli. In that study subjective aversiveness of faces was inversely associated with activity in bilateral dorsal lateral occipital cortex and precuneous for LSF images. In addition, greater BDD symptom severity was inversely associated with activity in the left dorsal occipital cortex and the right lateral occipital cortex for the LSF images, while in this study there were similar inverse correlations although with HSF and NSF images.
In the other-face processing study, the BDD group, compared to healthy controls, had greater left hemisphere activity in temporal, parietal, and prefrontal regions compared to healthy controls; group differences were most prominent for LSF stimuli but were also evident for NSF and to a lesser extent HSF stimuli(Feusner et al., 2007b). In contrast, in the current study there was lesser left hemisphere activity for LSF images in temporal regions. In the other-face study there was relative hypoactivity in the left and right occipital cortex for NSF stimuli, as in the current study, although not in the dorsal visual stream. Greater BDD symptom severity was found to be associated with lesser activity in left occipital and parieto-occipital (dorsal) regions for LSF other-face images(Feusner et al., 2007a), although not for HSF and NSF images as in the current study.
In total, these own- and other-face studies and the current houses study share evidence of abnormal visual cortical hypoactivity, in addition to lesser dorsal visual stream activity associated with greater symptom severity. However, the observation that specific aspects of abnormal visual processing in BDD are not identical across house, own-face, and other-face stimuli may be due to the differential relevance in the context of their symptoms. For example own-face stimuli are directly relevant to core appearance concerns regarding the face, and therefore may evoke emotional arousal and/or urges to engage in compulsive behaviors. Other-face stimuli may also be relevant to their symptoms, albeit indirectly, as individuals with BDD typically engage in scrutiny of others' faces to compare to their own. These symptom-relevant stimuli may engage prefrontal and/or frontostriatal systems and may lead to secondary top-down modulation of visual processing systems. House stimuli, which are not related to appearance preoccupations and are less likely to elicit emotional arousal or urges to engage behavioral sequences, therefore may be less likely to result in top-down modulation (however, this remains to be tested directly). Visual cortical abnormalities in the current study of house processing suggest the possibility of general, lower-level visual processing abnormalities in BDD, although it is still possible that top-down attentional modulation may affect these secondary visual systems.
Similar experiments using non-face/non-body objects have not yet been conducted in other disorders that share overlapping phenotypes with BDD, such as OCD, other anxiety disorders, and eating disorders. However, neuropsychological studies of visuospatial functioning have found similar detail-focused, piecemeal processing strategies on the Rey-Osterrieth Complex Figure Task in BDD(Deckersbach et al., 2000), OCD(Mataix-Cols et al., 2003, Savage et al., 2000), and anorexia nervosa(Sherman et al., 2006). These implicate abnormalities in executive functioning and/or visual memory encoding(Deckersbach et al., 2000). In addition, several neuroimaging studies in OCD have found possible abnormalities in visual processing systems including below normal glucose metabolic activity in parieto-occipital regions(Kwon et al., 2003, Nordahl et al., 1989), and abnormal hyperactivity when viewing biological motion in the ventral visual stream (left fusiform and left inferior temporal gyrus)(Jung et al., 2009). Future studies in these related disorders using similar stimuli as in the current study may be useful to explore possible shared phenotypes or endophenotypes of abnormal visual processing.
Behaviorally, the BDD group was slower on all tasks including the control task. It is unlikely that the results obtained for the BOLD signal were affected by offset of timing behaviorally because it was a blocked design and because we used temporal derivatives. Moreover, using response times as a covariate of non-interest, the findings in prefrontal regions for HSF images were essentially unchanged. Findings in secondary visual processing systems for LSF images were also essentially unchanged, although the power was reduced. This suggests that the between-groups differences are not just a function of slower behavioral responses for configural/holistic information.
This study has several limitations. The cross-sectional design precludes causal understandings of whether these abnormalities represent an endophenotype that predisposes individuals to develop BDD, or are secondary results of having BDD symptoms. Another limitation is that the temporal resolution of fMRI does not allow a determination of whether observed abnormalities are the result of top-down modulation of temporal and occipital systems. The sample size may have limited our power to detect small differences between groups, (however, this may not have been the case as a different study of 16 individuals with autism spectrum and 16 healthy controls using similar house stimuli found statistically significant differences of 0.02% signal change)(Bird et al., 2006). Due to the exploratory nature of this study as the first to investigate non-face/non-body object processing in BDD, and the fact that our hypotheses involved multiple regions that may be involved in distributed networks, we did not utilize a priori regions of interest to make use of small-volume corrections. It is possible that group differences in brain activity may have been influenced by different behavioral eye-tracking patterns; the use of an eye-tracking camera in future studies would help clarify this.
In conclusion, this study suggests that unmedicated individuals with BDD may have general abnormalities in higher- and lower-order visual processing, beyond that for their own appearance or for faces in general. These findings are consistent with a model of imbalances in global vs. local processing, which may exist for symptom-related and non-related visual stimuli. Future studies using techniques with higher temporal resolution such as EEG may help elucidate whether visual cortical abnormalities are the result of top-down modulation. Future studies will also be useful to characterize the inherited vs. acquired nature of these findings, for example, by studying unaffected first degree relatives or twins, or by studying individuals very early in their development of the disorder.
Funding for this study was provided by the National Institute for Mental Health (5K23MH079212 to Dr. Feusner).
We would like to thank Dr. Susan Bookheimer, Ph.D and Courtney Sheen, M.A. for their comments on the manuscript.
Results presented in part at the 18th European Congress of Psychiatry; March, 2010: Munich, Germany
The authors have no conflicts of interest to report.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


text:
Related videos
You need to upgrade your Adobe Flash Player to watch this video.
Download it from Adobe.
Download it from Adobe.
Peep Show
Submitted by Anonymous 2065 days ago
- 68I like
this videoThank you for voting!
- I dislike
this videoThank you for voting!
FavouritesAdd to favorites
Thank you for favoriting!
Subcribe to this video owner
Best videos of the day
66%05:54 Kamaya sl film 100%05:15 Captivating pussy in pantyhose looks as a real treasure 50%02:23 Mom and son hidden camera 85%05:15 Wicked bitch gets is pissing on 10-pounder of her stud 100%05:10 Milf enjoys stretching and fingering her bushy juicy cunt 92%03:30 And what if someone sees us??? 76%05:30 Teens asshole creampied 76%05:10 Casting honey leaves after hardcore penetration and ass hole 80%09:08 Before we've good old fashioned sex licking her hot hairy v 92%23:28 College blowjob anal fuck 71%04:48 Young Shemale Hottie Showing Off herself 90%42:25 Kinky husband and wife invite a hung stud for a bisexual ex


text:
Summer Internship Jobs in Toronto
Internship Toronto,
Summer Toronto,
Summer Student Toronto,
Summer 2016 Toronto,
Student Environment Summer Toronto
Canadian National Railway Company - Toronto, ON M5R 1A6
* Shadow B&S; Manager, Bridge inspectors, & Structures supervisors which will involve site visits, frequent work outdoors, and travel * Hi-Rail with Bridge Inspectors or withStructures Supervisors/Managers...
from: Beyond Network - 4 days ago
Deloitte - M5C 3G7 Toronto, ON
At Deloitte we are redefining what it means to be a professional services firm. We know that business as usual just won't cut it. Our culture is built on the collaboration, flexibility and innovation needed...
from: Deloitte - 4 days ago
LE CHATEAU - Toronto, ON, CA
• Open knowledge of corporate strategies & financial information, and influence over product, store operations, and other aspects of LE CHTEAU's business development decisions, allowing you to take ownership...
from: ca.jobdiagnosis.com - 9 days ago
Toronto, Ontario
Leonardo is a global innovator in technology solutions for the travel industry.
from: jobofmine.com - 29 days ago
Interviewing Now! H2 Concepts - Toronto, Ontario
UPBEAT WORK ENVIRONMENT ! If you don't like to have fun while you work, this is not the place for you. Work environment is incredibly important to us, and we are looking for candidates who work well in...
from: careerbuilder.ca - 23 days ago
Toronto, Ontario
You're a problem solver and have the ability to develop solutions to the problems that we can pretty much guarantee will arise on the job You're ridiculously organized You drive! (and have access to a...
from: jobofmine.com - More than 30 days ago
Amazon.com - Toronto, ON M5R 1A6
We hire software development engineer interns and Co-Op students into our technical teams based in North America. Please apply to this posting if you are interested in opportunities in our Vancouver, BC...
from: Beyond Network - 5 days ago
LE CHÂTEAU - Toronto, Ontario
Are you a leader who is able to encourage and drive your sales team to deliver higher results? Are you inspired by fashion and motivated by a fast-paced and changing environment? Then we're looking for...
from: careerbuilder.ca - 13 days ago
Toronto, Ontario
We sell that new type of hair band you may have seen (made of medical grade plastic - looks like an old telephone cord). Small, fun office - great location. We're sending this out to Influencers, magazine...
from: jobofmine.com (+1 source) - 14 days ago
Toronto, Ontario
Job Title: Online Sales Specialist - InternYour role will be to support the Inside Sales team by assisting with daily sales inquiries, logging sales inquiries into our sales system, and routing inquiries...
from: jobofmine.com (+1 source) - 22 days ago


text:
Frog prophesies by Ghesquiersby Björn Pohl - UKC Oct/2010
This news story has been read 4,080 times
38 year old Yann Ghesquiers, probably best known for having flashed an 8b+ slab pitch on Tough enough, a Multi-pitch on Madagascar I've got a feeling we'll hear more about in the immediate future, has made the first ascent of La proph�tie des grenouilles, at Rocher des Brunes, Brian�on, France. He gave it 9a, which would make it the 3rd of this grade in the region. The two other, San Ku Ka� and Cond� de Choc, both by Tony Lamiche, can be found at Entraygues.
Source: Brian�on-Escalade
This week's Friday Night Video is of Dani Arnold and David Lama's expedition to Alaska in 2015. On this trip... Read more
In case you somehow missed Alex Honnold's recent trip/lecture tour to the UK, the BMC have put together this short film about... Read more
James McHaffie has added to his impressive string of new ascents this year with a new route on the big, bold and adventurous area... Read more


text:
Rites of Spring
A.J. Bowen &
Anessa Ramsey
Padraig Reynolds
Starring: A.J. Bowen & Anessa Ramsey Director: Padraig Reynolds
Fear has a season
LOW STOCK: Only 3 copies left
|List Price:
|You Save:
|$17 (68% Off)
Available: Usually ships in 1-3 business days
Format: DVD
sku: JJ 9832D
Brand New
Amazon sells this DVD for $18.41, buying at OLDIES.com saves you 57%
This is the price to buy directly from Amazon.com or its featured FBA seller. Prices change often, this price was last checked on July 22, 2016. Amazon is a registered trademark of Amazon.com, Inc.
DVD Features:
- Rated: Not Rated
- Run Time: 1 hours, 21 minutes
- Video: Color
- Released: November 27, 2012
- Originally Released: 2011
- Label: Ifc Independent Film
- Encoding: Region 1 (USA & Canada)
- Note: Commentary
- Storyboards
- Poster designs
- Worm face art work gallery
- Trailer
- Sales trailer
- Aspect Ratio: Widescreen - 2.35
- Audio:
- Dolby Digital 2.0 Stereo - English
- Dolby Digital 5.1 - English
- Subtitles - English, Spanish
Performers, Cast and Crew:
|A.J. Bowen & Anessa Ramsey
|James Bartz, Andrew Breland, Shanna Forrestall, Skylar Page Burke, Grady Champion, Edward Saint Pe, Katherine Randolph, Sarah Pachelli, Sonny Marinelli, Marco St. John, Hannah Bryan & Jocelyn Amos
|Directed by
|Padraig Reynolds
|Screenwriting by
|Padraig Reynolds
|Music Performer:
|Patrick Casey, John Krovoza & Raif Derrazi
|Director of Photography:
|Carl Herse
Product Description:
A fractured gang of kidnappers are stalked by a mysterious creature while hiding out in an abandoned school as dissent grows amongst their ranks. It was the perfect crime -- abduct the daughter of a wealthy socialite, and simply lie low until the ransom is delivered. But as the criminals hole up in a derelict school and guilt sets in, a creature that emerges on the first day each spring to seek a sacrifice stalks the hallways in search of an offering. A.J. Bowen and Anessa Ramsey star.
1 Ichi: Origin (DVD)
View Details
$4.98 on SALE
1+1: Exploring The Kinsey Reports (DVD-R) View Details
10 Horror Movies (2-DVD)
$6.98 on SALE
View Details(2)
10 Horror Movies (2-DVD)
View Details
$4.98 on SALE
10 Items or Less - Season 1 & 2 (2-DVD)
$7.98 on SALE
View Details(10)
10 Items or Less - Season 3 (2-DVD) (DVD-R)
View Details
$25.98 on SALE
10 Movie Kids Pack (2-DVD)
$5.98 on SALE
View Details(3)
Sons of Kong: 10 Full-Length Movies on 3-DVDs (3D Pop-Up...
$1.98 on SALE
View Details(96)
Shark Week (Blu-ray)
98¢ on SALE
View Details(11)
TCM Greatest Classic Films Collection - Tarzan, Volume 2... (DVD)
$9.81 Super Savings
View Details(12)
Bigfoot (Blu-ray)
99¢ on SALE
View Details(22)
American Warships (Blu-ray)
99¢ on SALE
View Details(56)
Atlas In The Land of Cyclops (DVD)
View Details(15)
Movie Lovers' Ratings & Reviews:
Customer Rating:
Based on 5 ratings.
Based on 5 ratings.
Be the first Movie Lover to write an online review of this product!
Similar Products:
Product Groupings:
Sale Items:
Product Info:
- Sales Rank: 57,426
- Shipping Weight: 0.16/lbs (approx)
- International Shipping: 1 item
Reflections in a Golden Eye (DVD)
$2.98 on SALE
View Details(2)
Zombiethon (DVD)
$1.98 on SALE
View Details(4)
Possibilities (DVD + Music CD)
99¢ on SALE
View Details(18)
Madigan's Millions (DVD)
99¢ on SALE
View Details(6)
Baseball - Home Run Derby, Volume 1 (DVD)
99¢ on SALE
View Details(25)
To place an order or for customer service, call toll-free 1-800-336-4627 or outside the United States, call 1-610-649-7565
Open Monday-Friday: 8am-10pm, Weekends: 10am-10pm (Eastern Time)
Se habla Español! Spanish-speaking representatives available, Monday-Friday: 9am-4pm (Eastern Time)
Portions of this page © 2016 Rovi Corporation. For personal non-commercial use only. All rights reserved.
© 2016 OLDIES.com and its affiliates and partner companies. All rights reserved.
© 2016 OLDIES.com and its affiliates and partner companies. All rights reserved.


text:
WARSAW May 8 TriOil Resources, the Canadian upstream unit of Poland's top oil refiner, PKN Orlen, bought its local rival Birchill Exploration, making good on the promise to buy oil production assets to increase profitability, PKN said on Thursday.
TriOil bought Birchill for an undisclosed price from Luxembourg-based Bregal-Birchill Investments. PKN wants to finalise the transaction this quarter and expects it to double its Canadian upstream capacity.
State-controlled PKN booked its first net profit from oil production in the first quarter of this year with its last-year purchase of TriOil booking core earnings of 37 million zlotys ($12.3 million).
TriOil produced 330,000 barrels of oil equivalent in the first quarter.
($1 = 3.0099 Polish zlotys) (Reporting by Adrian Krajewski; Editing by Matt Driskill)
Our top photos from the past week. Full Coverage
Reuters special election issue
The key to understanding what's going on lies not with personalities, campaign strategies or party rules but rather with the voter. PDF Document
Trending On Reuters
Patents & Entrepreneurial Universities
Measuring and evaluating academic innovation


text:
Men's Fullsuits
Shop Men's Fullsuits online from the top brands. From the top hooded suits for the coldest waters out there, to the 3/2 short sleeve suit that will give you the most flexibility possible on a warmer summer day - we carry wetsuits for any climate and condition. Questions about wetsuit sizing or how they should fit? If you have any questions with regards to wetsuit sizing or choosing the right wetsuit for your climate, please give us a call and speak with one of our knowledgeable wetsuit experts. Utilize our expertise to ensure you choose the wetsuit that fits great and best meets your needs!
O'Neill Epic 2mm Short Sleeve Full Wetsuit$144.95
O'Neill HyperFreak Comp 4/3 Zipless Wetsuit$289.95
O'Neill Epic 4/3 Back Zip Wetsuit$184.95
O'Neill SuperFreak 4/3 Wetsuit$229.95
O'Neill Psycho Freak 4/3 Back Zip Wetsuit$519.95
O'Neill Heat 4/3 Wetsuit$299.95
O'Neill Psycho Tech 4/3 Hooded Chest Zip Wetsuit$449.95
O'Neill Psycho I 4/3 Chest Zip Wetsuit$359.95
O'Neill HyperFreak 2mm Short Sleeve Full Wetsuit$229.95
O'Neill Psycho I 4/3 Back Zip Wetsuit$359.95
O'Neill Psycho Tech 4/3 Chest Zip Wetsuit$419.95
Quiksilver Syncro LFS 4/3 Back Zip Wetsuit
Regular Price: $209.95
O'Neill HyperFreak 2mm Wetsuit$239.95
Quiksilver AG47 Performance 4/3 Chest Zip Wetsuit
Regular Price: $324.95
Billabong Foil 4/3 Chest Zip Wetsuit
Regular Price: $179.95
O'Neill Psycho Freak 4/3 Chest Zip Wetsuit$509.95
O'Neill Mutant 4/3 Wetsuit with Hood$369.95
Rip Curl Dawn Patrol 2mm Short Sleeve Back Zip Wetsuit$139.95
Rip Curl E-Bomb 4/3 Chest Zip Wetsuit
Regular Price: $339.95
Billabong Foil Plus 4/3 Chest Zip Wetsuit
Regular Price: $209.95
Quiksilver Syncro 4/3 Chest Zip Wetsuit
Regular Price: $184.95
Rip Curl E-Bomb Pro 4/3 Zip Free Wetsuit
Regular Price: $319.95
Rip Curl Flash Bomb 4/3 Chest Zip Wetsuit
Regular Price: $439.95
Billabong Furnace 4/3 Chest Zip Wetsuit
Regular Price: $409.95


text:
By doing some quick math, it becomes clear that by speaking just one language, organizations are only reaching about a quarter of online users. To expand reach and engage with a wider audience, global businesses must adopt multilingual communications. Otherwise, they risk abandoning potential customers who will instead turn to competitors who communicate with them on a local level.
Apr 05, 2011
Wildfire PR, a public relations consultancy for information technology, telecoms, consumer technology, and B2B companies, reported that IT professionals were most likely to turn to social communities or search engines than to online news or industry presses when doing research for IT purchasing decisions. Social networks and online communities were ranked the most useful information sources by 58% of IT decision makers, followed by search engines, online news sources, and IT industry press sources.
The study also found that IT print publications are becoming less popular, and a quarter of all IT professionals surveyed said they got most of their IT news online. For both regular news and IT news, the respondents' most popular sources were online. All of the surveyed IT professionals were U.K.-based.


text:
construction management jobs near Baltimore, MD
Refine your searchClear Filters
Date Added
More Filters
DAS Field Construction Manager
TRM (Tower Resource Management) - Hanover, MD
Engineering or Construction Management are a plus. Obtain local permits and construction licenses. A high-growth convergent infrastructure & services company is...
Pre-Construction Manager
Erickson Living - Catonsville, MD
Construction Bid Management. Design Scope Management. Construction cost estimation experience. Construction management, building science, architecture, or...
Construction Manager 4
KCI Technologies - Sparks, MD
KCI Technologies, Inc., a dynamic employee-owned engineering and construction management firm. Knowledge of the construction process, particularly in highway...
Senior Construction Manager
MWH - Baltimore, MD
Use Primavera Contract Management, Release 14 for construction document management. Provide construction management supervision on assigned projects....
Construction Manager I
AECOM - Annapolis Junction, MD
Possess a thorough knowledge of all engineering disciplines, construction technologies and job site management....
Transportation Construction Manager - Baltimore, MD
CH2M - Baltimore, MD
Certified Construction Manager certification from the Construction Management Association of America (CMAA) preferred....
Senior Transportation Construction Manager - Baltimore, MD
CH2M - Baltimore, MD
Certified Construction Manager certification from the Construction Management Association of America (CMAA). Our construction management opportunities provide...
Job ID: 10635 Construction Manager (UD, OH, Substation & transmission)
Myriad Technical services - Baltimore, MD
In-depth knowledge of materials, BGE construction standards, regulations (OSHA), and safety requirements for electric distribution and substation construction....
Construction Manager
Veterans Sourcing Group - Baltimore, MD
At least 10 years of construction manager experience. Individual shall have demonstrated skill in construction project management....
Commercial Construction Manager
SolarCity - Baltimore, MD
Assist Project Manager in the development and management project budgets. The Commercial Construction Manager reports to the Project Manager in the project team...


text:
New York-based jazz composer and bassist Ben Allison writes highly-melodic, evocative jazz tunes that draw from rock, pop, R&B and 1960s instrumentals, but still stay true to jazz. On Little Things Run the World, the "Downbeat" magazine favorite and his newest group, Man Size Safe, team with guest saxophonist Michael Blake. The quintet blows through eight numbers that run the gamut from Latin-tinged excursions ("Respiration") to rock-styled workouts ("Blowback") to multi-part, multi-genre extravaganzas ("Four Folk Songs"). Allison underpins each tune with complex, probing upright bass lines while letting Blake and trumpet and flugelhorn player Ron Horton handle most of the melody. Allison's style, it's been noted, is unique in that it's not hard core improvisational jazz or Kenny G-like easy listening. In a way, Allison is a classicist, mainly drawing from the late 1950s style of Miles Davis and the languid, bittersweet writing of Billy Strayhorn in the 1940s. What keeps him from being a revivalist is the fact that he incorporates modern influences, one being his cover of John Lennon's "Jealous Guy". This CD, his eighth, finds him typically referencing works of science (the title refers to a book by biologist E.O. Wilson) and politics (the band's name references a purported oddball object in Vice President Dick Cheney's office). Since you can't really say much politically on an all-instrumental CD, titles and band names are pretty much all Allison has to gets his non-musical points across. But you don't really need to know that to groove to these harmonically-rich, exquisitely played compositions.
- Multiple songs MySpace
Michael Blume 'When I Get It Right' (EP stream) (premiere) // Music
Crystal Castles "Concrete" (Singles Going Steady) // Music
Big Top Heartbreak "My Breath Killed the Roses" (video) (premiere) // Music
Maggie Szabo "Touch The Ground" (audio) (premiere) // Music
Terribly Yours "Golden Age" (audio) (premiere) // Music
20 Questions: Beyond the Wizard's Sleeve
// Sound Affects
"The skull-masked DJs have made a name for themseves with melodic, emotional dance remixes. Now, after a decade of scant singles and comps, their insanely diverse debut finally arrives.READ the article


text:
Cart Checkout 0
Your Help is Here! 800.743.3206
VIP Membership Terms: Normally $24.99 per year, but your Web Exclusive deal means you enjoy 3 months of VIP Family Benefits for $1.99. Check out your savings and benefits below.
Cancellation: Rest assured you can cancel your new membership at any time during the year at a pro-rated rate, simply call your VIP Hotline at 800.543.7309 or click here to submit your cancellation request. Benefits and prices are subject to change.
Want more info? Click here and read 'til your heart's content or call your VIP Hotline at 800.543.7309
Men's R-Gear
Training Day Short Sleeve
Base Runner Short Sleeve
Run Like Hell Graphic Short Sleeve
Perfect Run Long Sleeve
Men's Nike
Run Trail Running Tank
Run Tie Dye Tank
Men's Under Armour
Coolswitch Run Singlet
Coldgear Infrared Run 1/2 Zip
Perfect Run Short Sleeve
Men's ASICS
Performance Run Singlet
Run Twist Longsleeve T
Performance Run Long Sleeve Crew
Men's Adidas
Supernova Beyond The Run Hoodie
Men's Saucony
Run Strong Sportop
Heatgear Flyweight Run 1/4 Zip
Charged Wool Run Longsleeve
Heatgear Flyweight Run Shortsleeve
Performance Run Sleeveless Top
Men's De Soto
SDS Run Singlet
Charged Wool Run Shortsleeve
Run Singlet
Men's Zoot
Run LTD Singlet
Run Team Singlet
Back to top
Become a fan and follow us.


text:
Let's meetup at Charlotte's Blueberry Farm to visit, enjoy the first day of Fall and pick some blueberries! Bring a beverage and a snack to share! We'll enjoy a casual potluck style picnic, each other's company and some relaxing blueberry picking! Be sure to bring a container to gather the berries in!
Since the Blueberry Park Project started in 1999, more than 3,372 bushes have been trimmed to ground level and are now producing fruit. Five varieties of blueberries grow in the park. Picking season runs from July through September each year (dependent on weather). Metro Parks does not use any pesticides or fertilizers on the blueberry plants, they are grown naturally. There is no fee to pick the blueberries which are first-come-first-serve during picking season.
I've never been there. This sounds like fun. I'll see if I can make it!
0 · September 20, 2013
Meetup members, Log in
By clicking "Sign up" or "Sign up using Facebook", you confirm that you accept our Terms of Service & Privacy Policy


text:
Fla. man shoots officers, cuts hostages during standoff
By Macollvie Jean-Francois
The Sun-Sentinel
HOLLYWOOD, Fla. — A tip for anyone having houseguests over: Don't hold them hostage, stab and point a handgun at them, especially with police surrounding your home.
That's the treatment Alfred Eugene Juska, 64, gave his visitor Algimantas Bronisas, 58, at his apartment in the 1500 block of Arthur Street for several hours between late Saturday night and early Sunday, said police spokesman Detective Carlos Negron.
Police shot Juska after he fired at them during a four-hour standoff and refused to surrender, Negron said.
Copyright © 2013 LexisNexis, a division of Reed Elsevier Inc. All rights reserved.
Terms and Conditions Privacy Policy
Full story: Fla. man shoots officers, cuts hostages during standoff
Join the discussion
Latest Product News
Video: Texas police save robbery suspect from burning car after pursuit
Video: Iowa cops praised after stop of college football player
Man hurls Batman 'batarang' throwing star at Seattle police, arrested


text:
Here's A Breakdown Of The Military-Style Gear Used On The Streets Of Ferguson, Missouri
Published 6:38 pm, Thursday, August 14, 2014
The protests in Ferguson, Missouri over the past week came to a tense head on Wednesday evening, as heavily-armed police officers — many wearing military-style uniforms and gear — fired rubber bullets and tear gas into the crowd to get them to disperse.
As we have seen in many small-town police departments, some officers in Ferguson, with a population of 21,000, looked more like soldiers than members of law enforcement as they responded to protests after a cop shot an unarmed, black 18-year-old.
In fact, the St. Louis County and Ferguson police departments have both received equipment previously used by the military under the Pentagon's 1033 program in recent years.
Reports of cheating on the ACT in China reflect a persistent and 'very disconcerting' issue to US colleges
Manchester United Players are now banned from playing Pokemon Go on certain days
Here's what happened when I finally got to drive the car of my childhood dreams
This chart of Yahoo's market cap is just the most outrageous thing (YHOO)
Yahoo has made its exit as an independent company — here's what happens next (YHOO)
We looked over some of the photos from recent days and identified equipment that is similar to that used in military operations overseas. While some of these items have obvious crossover from military to police usage, others being used — like sniper rifles being aimed at unarmed crowds and armored vehicles — seem to serve more to intimidate rather than help with crowd control.
It's worth noting that while the majority of demonstrators have been defiant, but peaceful, some have been seen throwing rocks, Molotov cocktails, and bottles. However, the local police tactics have not been successful in deescalating the situation, and on Thursday, Missouri Gov. Jay Nixon (D) pulled and replaced them with State Highway patrolmen (The situation has drastically calmed down in response).
Here's what some officers were wearing:
(h/t T.M. Gibbons-Neff at The Washington Post)
Join the conversation about this story »
See Also:
- A Former Police Chief Explains All The Ways The Cops In Ferguson Made A Bad Situation Worse
- This Is The Terrifying Result Of The Militarization Of Police
- Robin Williams Had The Perfect Response When Troops In Kuwait Interrupted His Comedy Show In 2007
- Huge Terrorism Financing Case Finally Goes To Trial Monday
- US Military Conducts Four More Airstrikes In Iraq
SEE ALSO: This Is The Terrifying Result Of The Militarization Of Police


text:
Foursquare © 2016 Lovingly made in NYC & SF
Regent Suvarnabhumi Hotel
30/1 32/1, Soi Ladkrabang 22 (Ladkrabang Rd)
"Clean. Friendly. Good airport transfer. Close to airport. Nice room with kitchen area. Restaurant and massage. Good service."
Emporium Suites by Chatrium
622 Sukhumvit Rd.
"wonderful place..my favorite hotel in the world"
The Tawana Bangkok
80 Surawong Rd
"Very good hotel. Welcoming and available staff. I do recommend this place which has reasonable price!"
Good to go
Created by Themokk158 items • 2 followers
Ben's Favorite Hotels
Created by Benjamin 🚀24 items
Make sure your information is up to date. Plus use our free tools to find new customers.
Download Foursquare for your smart phone and start exploring the world around you!


text:
NOTE: The Illinois History and Lincoln Collections Reading Room will be closed from August 2-8. Books and manuscript collections may be requested for use in the University Archives Reading Room (Main Library 146) during this time. The University Archives is open 8:30am-5pm, Monday, Tuesday, Thursday, and Friday, and 10am-5pm on Wednesdays.
Paging of IHLC materials will be available from 9am-12pm and 1pm-4pm. Please call the University Archives Reading Room at 217-333-0798 for assistance with requests for IHLC materials between August 2 and August 8.
Lodge, William E. (1834-1901). Collection, 1856-1918 | Illinois History and Lincoln Collections
William Edward Lodge was a prominent attorney, real estate dealer, newspaper publisher, and active spokesman for the Democratic party. He spent his adult life in Monticello, Piatt County, Illinois, where he built a successful law practice specializing in collections, loans, and land sales. Lodge also served as an attorney for several railroads. His wife, Frances Piatt Lodge, was the granddaughter of James A. Piatt, for whom the county is named.
The Lodge collection contains the records of a law practice that spanned the second half of the nineteenth century. The Lodge papers, which make up most of the collection, consist primarily of a wide ranging, incoming business correspondence. Little outgoing correspondence is found in the collection. Important correspondents include Samuel Allerton, Joseph G. Cannon, John A. McClernand, William McReynolds, and Virgil S. Ruby. Notable businesses that dealt with Lodge included David Bradley and Co., the Chicago and Paducah Railroad, Deere and Co., R.G. Dun and Co., the Illinois Central Railroad, W.W. Kimball Co., the Martindale Law and Collection Agency, Pearsons and Taft, Rand, McNally and Co., and the Wabash Railroad. Lodge also corresponded with several collection agencies, lending institutions, and a host of other attorneys.
Other items found in the Lodge papers are a valuable collection of Civil War letters and a plethora of documents and business records. Set off separately are the papers of the Bruce Morris Reynolds family of Cincinnati and Covington, Kentucky, and the papers of Edwin B. Hale of Cleveland, owners of extensive land holdings in central Illinois. The Lodge collection also contains the papers of three of Lodge's four partners, James L. Hicks (1888-1901), Harvey E. Huston (1870-1886), and Hamilton C. McComas (1859-1862); correspondence of Piatt, Hubbell & Co., operators of a Piatt County grain elevator in the 1870s; and correspondence of George Hatch, a central Illinois livestock dealer of the 1850s and 1860s. Francis J. Brooks, a Monticello motion picture projectionist and local historian, collected and preserved the material in the Lodge collection.
The Piatt County Historical and Genealogical Society received the material in this collection from the estate of Francis J. Brooks, donating it to the Library in 1987 and 1990.


text:
How to get rid of cable and still watch your favorite shows! Money Saving Tips for the New Year!
Cutting cable isn't as difficult as you think, and a great way to trim the budget. This family did it and still gets live TV for free - lots of great tips!
DIY Bisquick mix, this stuff is awesome! Homemade baking mix makes pancakes waffles and more!
Being Frugal | Learn how to Live on a Budget
The Ultimate Printable Budget Binder - featuring 10+ amazing printables that'll make you want to get on track with your budget! Free!
The story of how one family paid off over $20k ($22,047.93 to be exact!) in less than 9 months on one income, plus 9 crazy things they did to be debt free. www.growingslower.com #debtfree #frugalliving
Is your new year resolution to get out of debt? Here is Dave's proven method for becoming debt free.
Making your own laundry detergent is easier than mixing up a batch of cookies and costs only pennies per load. Follow the steps below to make your own.
Tips to cash only spending and budgeting.
homemade yellow cake mix: 2-1/4 cups all-purpose flour; 1-1/2 cups granulated sugar; 3-1/2 tsp baking powder; 1 tsp salt. To this dry mix,, add; 1-1/4 cups milk; 1 stick butter, softened; 1 tbsp vanilla extract; 3 large eggs.
Homemade Brownie Mix
If you want be wealthy you have to do what wealthy people are doing.
Spend Less Money - New Ways to Save Money - Woman's Day http://www.womansday.com/life/saving-money/spend-less-money#slide-1
When you're on a budget, life without a mortgage can be hard to picture. But here's a little secret: You can pay off your mortgage without starving your budget.
When you're on a budget, life without a mortgage can be hard to picture. But here's a little secret: You can pay off your mortgage without starving your budget.
DIY Laundry soap & a full review after using it for one year. A must pin for saving lots of money!!!
Copycat Homemade Pumpkin Pie Spice - blend spices you already have on hand
New Nostalgia – No Grate No Cook Liquid Laundry Detergent
When it comes to money, we can all benefit from a few quick tips. Check out these 20 quick money lessons that might just transform your life.
How to buy real food on a budget . . . this is a great post!
How to Make Your Own Fajita Seasoning Mix by realdinnerlife #Seasoning #Fajita
30 Ways to Save Money at Home. Some awesome tips! #save #money #finances
12 ideas for How to Save for a Vacation - travel tip budget trip StuffedSuitcase.com
Cream of Something Soup Mix - use this mix & water in place of canned soup. This is much less expensive & better for you than canned soup.
72 ways to cut your spending by 400 a month and save 4000 a year...Pin now, read later, cause this list is FULL of great ideas!! #budget


text:
Date Published: 02/27/2014 8:48 AM
I received this message when opening my windows 7 laptop.
there was a problem starting.
Operation did not complete successfully because the file contains a virus.
Is it safe to delete this file?
What should I do?
View Local Answers... Can't find the answer to this question?
No answers yet.
Can you answer this question?
Can you answer these?
- Answer how can i get this on my desk top
- Answer error 8000ffff
- Answer After I scan with MSE there is an amber coloured scan shows up instead for green
- Answer 워커힐바카라∏【VIP777WEB.COM】바카라사이트
- Answer Internet Police
- Answer I was remotely accessed and think I was scammed What do i do?
- Answer Can I delete the dmwu.exe file in the Windows/System32 folder
- Answer security esencial no detecta malware
- Answer Microsoft Security Essentials -- XP -- End of Life Pop-Up/Notification
- Answer Microsoft Security Essentials and MalwareBytes
[Some content on this page is from Microsoft Virus and Malware Community]


text:
Conquer Your Cravings
Dr. Oz gives you the tools you need to stack your diet in your favor to keep you fuller, longer while helping you shed extra pounds faster and easier.
HPV is not just a young woman's problem – 80% of all women will be infected by the time they're 50. The virus can lie dormant for decades, never showing up on a pap smear, before causing oral, anal and cervical cancers. Could you be at risk?
View Part 2 of The Shocking Truth About HPV.
Watch Dr. Oz explain the dangers of unprotected oral sex.
See Dr. Oz answer your questions about HPV.
Learn more about the connection between HPV and cancer.