text:
Georgia State Head Coach Bill Curry
It's obvious that what happened today was a failure of leadership by all of us. I've seldom felt better about preparation, and I've seldom been more disappointed with a result. I don't have to tell you about the turnovers and allowing them to run through us the times we couldn't afford that and the incredible foolish penalties. I would love to play a good game against ODU someday, but we seem to save our worst for ODU. So hat's off to a good job by that team. We didn't find out today just how good they are because we really didn't test them. We gave them opportunities at every turn and they took advantage. So we go back to work and correct the foolish penalties, the turnovers, the tackling, the blocking, and the lack of attention to detail and get ready for the next one. That's what football teaches you.
Can you talk about the decision to wait to bring in Little until the fourth quarter?
We talked about it all along, and Bo (Schlecter) had started out very nervous a week ago and then rallied to play very well. He did some good things today. So we wanted to stay with him a reasonable amount of time before we went to Drew (Little). But who knows. Maybe we should have done it in the second quarter. You can always look back and wonder if things could have been different before the score got to where it was when we finally put him in.
On the blocked punt and the partially blocked punt, did ODU show you something in the special teams' packages that you didn't expect or hadn't seen?
Our punt protection requires that the punter step in a certain direction, and it's toward the long side of the shield. We are not sure if Matt (Hubbard) did that or not. It looked like he did not. They should not be able to come through the shield like that regardless. The protection should hold up. He's a wonderful punter. He gets the ball off quickly. That's not an excuse. It might have been the same if we had Bo in there. Bo had a foot issue. He couldn't punt today and that's the reason Matt was in there.
Did you see anything in the warm-ups with the players before the game that led you to believe 'this is not going to be good'?
No were weren't flat. We were exuberant. We were bouncing around. We were coming off the ball. We were handling the ball well. We did everything well in warm-ups. But warm-ups don't count. Everything that would indicate that we were going to play well has been present. We just didn't. That's always leadership. That is a failure of leadership.
… On the coaches' part?
You have to have their attention. You have to know you have their attention. It has to be in the finest detail. It has to been in the details of staying in front of people when you are blocking on kick-off returns and punt returns. It has to be in the subtle nuances of where you throw the ball. Both the quarterbacks that played today have been out there every day so they know what to do. The receivers know what to do. The guys providing protection have been out there every day. There is just no excuse.
Any positives you can take away from this game?
The only positive I can think of is that out of these situations it has been my experience that good teams always rally and fight back to correct it. That is all I can give. We should get a chance to go back and build off this and learn how to not make excuses and feel sorry for ourselves.
Can you talk about the momentum change at the block punt that led to the TD right before halftime? You come out and are inside the 50 in three consecutive possessions and are forced to punt three consecutive times.
That was huge, absolutely huge. When come out in the third quarter and you have the ball, you drive it for a score. We made a big play. We get the ball in scoring position three times and come away with nothing. That is a very deflating thing. We could have just driven ourselves right back into the game. Sometimes you are better off if you do see these things coming because you know that there are some subtle distraction with your team, but I didn't see this at all.
Did the defense just wear down in the fourth quarter?
Our defense is in shape. They hurt us early in the game as much as they did late. We had long stretches where we stoned their running game. That is what you have to do, just keep doing that. It wasn't a matter of wearing down. We didn't wear down in the first quarter and they ran the ball well. We've been practicing at this pace since last March. This is not new to us. This doesn't surprise us. This wasn't a conditioning thing. This was a concentration thing. This is staying on your feet, keeping your head up, ripping across the blocker's neck, turning his body instead of yours being turned and tackling the guy. When we did that we were fine. We have to learn to be the same team all the time.
Old Dominion Head Coach Bobby Wilder
We got pressure all day long. Even more so I thought our offensive line really dominated the football game. We were able to run the ball consistently. We kept the able on offense and Georgia State stayed primarily in their three down front. They didn't bring a lot of pressure and they were playing coverage so they were basically telling us, 'We aren't going to let you throw the ball outside to your receivers, we are going to make you run it,' so that's what we did. We were successful doing that.
I thought the key to the game and what really turned it were two plays back to back. We were going into score to go up, I believe, 20-3 and we fumbled in the end zone and they brought it back cut it to 13-10 and what got it back again was when we blocked the punt. We blocked the block and Blair Roberts scored. Probably one of the funniest things I've seen in 23 years of coaching was Blair Roberts almost wasn't on the punt block team because he had to go to the bathroom. We almost lost him to a restroom break but he agreed to stay through it, scored a TD. That really turned it when we blocked the punt and scored. That's when the momentum swung.
Any word on Alex Arain or T.J. Cowart?
I have not heard yet about Alex. He came in for an x-ray on his neck. J.J. Williams also came in for an x-ray on his neck but he was cleared. T.J., right now, we got the x-ray. We are not sure at this point if the wrist is broken. We will know for certain tomorrow, but he did get it banged pretty good. He was going to an interception, almost had it and collided with one of our guys.
Big win here today against a future conference opponent, how do you guys feel coming back?
I feel really good about a football team as I assess us right now. I thought this would be a really big test because I felt like Coach Curry and his staff had a better football team. I thought they were better this year than last year. Height, weight, speed. They are bigger, faster, stronger. For us to dominate the score, the way we did, I'll need to see the video to see if we dominated the game, but we certainly dominated the score and I think that speaks very well for where we are as a team right now. We needed to run the ball today. That was something we were average with last week. We needed to run this ball this week. I thought that was the difference in the game, the ability to run the ball.
Did you feel like you guys were maybe could have been up a little more than you were early on?
There is no question that the turnovers really hurt us early on. The mark of a good football team is number one taking advantage of turnovers, which Georgia State did, I give them a lot of credit. They took advantage. That was a heck of a play when they scooped the ball up in the end zone and ran all the way down to our 10 yard line with it. That is a mark of a good, well-coached football team, which they are. But I did feel like we should have been up by a few more scores, at 20-17. If you look at last year's game, they are up 6-0 then turn the ball over four times and then we are up 34-6. We hung in there with it and our motto as a team is play the next play and not get too down when something bad happens. I'm proud of our kids for that. We didn't get too discouraged with those mistakes.
September 11th, 2011
9:54 am
September 11th, 2011
9:56 am
Reported attendance was 11K. There was no way there were that many people and even the AJCGSU Twitter feed acknowledged that. I'm disappointed more fans couldn't come out to see how our team stacks up against another start-up program.
September 11th, 2011
10:30 am
And you guys think you can compete with Georgia Southern? You have a few more years before you can step on the field with the 6 time national champs. Look at the polls on Monday THE G.S.U. will be # 1.
September 11th, 2011
11:00 am
Never heard of any of those schools that you beat in order to obtain your 6 D-II trophies in. Congratulations on your irrelevance. Thanks for supporting GSU's blog and citing accomplishments form last century.
September 11th, 2011
11:01 am
September 11th, 2011
11:45 am
Whenever you beat someone of relevance then you can talk…. and the 6 national titles are from the FCS, the same NCAA division that Ga St plays in. Let me know how it feels sitting at home when GSU is going for national title #7. Big talk from a school that has won nothing.
September 11th, 2011
11:46 am
Actually our last national championship was this century, in 2000, back when y'all were still dreaming of getting to maybe play one day…also lets understand that those were all against the same level of competition that you are are losing against now..when Southern is playing in Frisco in January well be sure to send ole coach curry a nice postcard
September 11th, 2011
11:56 am
You guys are 7-6 overall with wins over 3 of the worst fcs schools, an impressive 2-0 against non scholarship schools, WOW 1-0 against Div II god awful Clark Atlanta, and 1-1 in the NAIA.
September 11th, 2011
11:57 am
I like how more southern trolls are posting here then anyone else… Nobody even said anything about southern, why are u here?
September 11th, 2011
12:07 pm
Well i am here because i am a fervent sports fan and like to be educated about all the sports going on in our awesome state…but when o here ignorant statements like this one:
"Never heard of any of those schools that you beat in order to obtain your 6 D-II trophies in. Congratulations on your irrelevance. Thanks for supporting GSU's blog and citing accomplishments form last century."
It causes me to want to set the record straight. I love idea of a GSU- GA St rivalry, just not time for that to happen yet, for your guys sake.
I think its the "undeserved since of accomplishment" attitude that is causing the GSU fans in the state to get pissed off. Y'all have been here for a minute but feel like you can make claims like the above statement.
September 11th, 2011
12:19 pm
Its all the past comments from ga st fans talking trash about Southern. You have no ground to stand on when your record and youth as a program is what it is. In Ga Southerns 2nd year in football we won a national title. Ga Southern has the 4th best winning percentage in all divisions of college football.
September 11th, 2011
12:42 pm
I attended the game. The difference in the game was the offensive and defensive line play.
Skill players are relatively equal. Old Dominion's defensive line was too big and physical for GSU. There offensive line was much the same. There will have to be a large influx of JUCO of D1 transferes to make GSU relevant in the CCA or its going to be hard to get people in the gate.
September 11th, 2011
1:38 pm
Is Georgia Southern so boring that you need to keep up with other schools? I do not care what Georgia Southern does. You could win all of your games and I'll never know because I don't care. Go Panthers!
September 11th, 2011
1:45 pm
@PT, agreed however I also believe our play calling was highly inadequate. Hill or Russell should have gotten us out of the deep hole we were in on the 9 yard line. No offense to Bo but he is too inexperienced to handle the ball on our goal line. Additionally with a team that has blocked 15 punts and FG's you would think that we would have had a plan for that. We did not do any of the things we said we were going to do. The running game was not emphasized, Donald Russell was barely used and Bo should have been pulled sooner since he just wasn't clicking. Both Little & Hill should have played sooner, Little should have been given more time to warm up (i.e. w/ running plays and short passes). Most of all we need to be better at making adjustments while the game is happening. I'm just not sure we are scouting like we should be as most opposing coaches interviewed are calling us predictable. Overall however I believe we have a great foundation and if we can become a little more dynamic and less predictable it should go a long way. We certainly have the talent to compete.
September 11th, 2011
3:11 pm
Georgia State football…..a program that should have never been started. Georgia State was a decent commuter, graduate school. Trying to be a traditional university with all the frills???? Huge mistake! Carl Patton should have his butt kicked.
September 11th, 2011
5:58 pm
26,000 for the opener and now less than 11,000 for the bigest game on the home schedule. Poor marketing effort by GSU. ODU has sold out every seat for every home game before the season begins. Effort of their mkt staff overshadows the effort by GSU. Thats Norfolk folks. Always considered a second tier city with little enthusiasm for sports. Not to mention it is 6 times smaller market than ATL. Their population is military and family. About 1/3 of the total population. Half of them are in port or deployed otherwise. The other 1/2 has no ties to ODU. Poor, poor effort GSU.
September 11th, 2011
6:22 pm
This is a program that has no reason to exist. I hope Kennesaw State see the handwriting on the wall. They will never compete for the average fans. Even Georgia Tech has trouble filling an Atlanta stadium.By the way I have an advanced degree from Georgia State.
September 11th, 2011
6:39 pm
Atlanta fans SUCK!! Look @ Tech, look @ the Thrashers, they'll turn their back on the Braves & Hawks in a second. All they care about is going to the mall spending money they don't have and living their meaningless little lives in their trailers or cookie cutter subdivisions vicariously through their worthless uneducated children. The only reason UGA has such a big following is all of the Sub-Alum rednecks that have adopted them and have nothing else to live for.
September 11th, 2011
6:59 pm
PS I don't totally blame the GSU alum. Accept for the handful of athletes who have come and gone 99.99% of the 170,000 alum never went to GSU because of athletics and I would venture to guess that about 155,000 of them had absolutely no idea we even had any sports programs. School spirit is a cultural thing that needs to be cultivated over time. Each year as we graduate the approximately 5,000 students I believe they will become more involved then the previous alums if our program continues to progress. I agree with you the marketing effort needs to be upgraded (and I have a million ideas about that) but the quick fix is to get the students and their families to the games.
September 11th, 2011
8:47 pm
Wow GSWho @6:39. Did your dog die today or what?
That's some pretty high and mighty talk. And you're life is so much better than most Atlantan's why exactly? Please enlighten us on your take on the meaning of life, we're dying to know what makes you and your life so superior.
Don't disappoint us now. There's about five million Atlantan's you're better than, and we need to know your secret to life.
Just kiddin. There's about five million Atlantan's that just think you're an A/H!
September 11th, 2011
9:00 pm
Part of the problem is the Georgia Dome is too big. 11,000 or even less is actually a good to decent turn out by FCS standards. GSU does better on attendance with Thursday and Friday night games. They should schedule more of those.
Funny how the Georgia Southern people are so quick to call for Georgia State (or even Kennesaw State) to shutdown its football program. Trying to bury the Georgia State program after any loss or if attendance slips.
Why does GSU alum Bill want both GSU and KSU to give up football?
September 11th, 2011
9:07 pm
Watched the game on Comcast. Yikes. Defense looked rough. The threads on who is the "real" GSU are entertaining. About as irrelevant as it gets on any level but worth a read to make me feel …about 40 IQ points higher. I hope to see either "real' GSU team at a Nova or U of D game. You guys must be a hoot
September 11th, 2011
9:57 pm
I'm not sure if having two GSU's in the same state is a blessing or a curse. It created an instant rivalry between two football teams that have never met. When Kennesaw State starts their program, they might feel left out among the intra-state rivals. Although Georgia State might be the most likely rival to KSU so Georgia State might end up with two hated in-state rivals.
September 11th, 2011
9:58 pm
@ Big Ol Stinger
Thanks for making my point I'm sorry if my comments resemble you. While I am not privy to the meaning of life rest assured, I am working on that. I am saddened that your philosophical ability was limited to five sentences before you needed to resort to vulgarity. I'm sure if you ponder long enough you will muster a full paragraph before degenerating. Regardless, other than your distaste for my god given, first amendment singular opinion, I'm not clear as to what specifically you have added to the aforementioned discussion. Please be advised if you choose to continue this discussion I will oblige however I will not descend to your plane (i.e. you will remain the lowest common denominator in this forum).
September 12th, 2011
6:56 am
Yeah, I didn't figure you'd have a real answer.
No apology needed, I'm doing pretty well as a matter of fact, and so are my kids. I do wish my portfolio would start to recover but I've got plenty of time for that.
That's quite an impressive vocabulary you have there. Thanks for making my point as well. I don't need to insult 5 million people to feel better about myself. I'm sorry that you do. I'm also sorry if my last comment resembles you, too.
Your butler probably has your tea and crumpits ready by now. Don't forget to stick out your pinky. Toodles.
P.S. I hope those were complete paragraphs, I spend a lot of time proof reading and editing. Pffffffffffffttttttttttt.
September 12th, 2011
8:06 am
Finally made a game. Man, that place was empty. GSU has to get an off campus stadium not named Georgia Dome and soon. There is nothing other than beer that was entertaining about being in an empty building. On the plus side, GSU has football and lot don't and have a big alum base that increases every year and has the kind of programs that should bring in some major dollars if you can keep them involved, post grad and football certianly helps that. And yes, as said above 11K is good for 1AA I would think, but if there were 11K there Sat then I have 30 toes. Cause I have ten. True support for this program can't be manufactored. All the ESPN love for Curry don't mean diddly. Playing in any conference GSU finds won't mean attendance swells. It has to be done the hard way in Atlanta, and that takes time. I fear GSU fans thought that the Dome doors would open up and it would just happen. Its going to be a long road, uphill. But, again, you got a program so its a start.
September 12th, 2011
8:36 am
It's games like these that make me wonder if GSU should have a football program in the first place- bad playcalling, bad execution, little fan support and a blowout loss. When does basketball season start?
September 12th, 2011
9:38 am
1) Georgia Southern is the greatest sports team to ever take a field of any kind. Is that better? Will that make you go away or at least quit trying to make everyone see you have won championships? If they don't know by now it's because they don't care. Quit being so sensitive about what a few of our fans say on the INTERNET. Let me repeat that, the INTERNET.
2) Even at 11K in attendance (lowest ever) Georgia State is still 15th for the week in FCS attendance. Like GSun78 said, the Dome is too big for State right now, here's hoping they grow into it.
3) This was one loss, the program doesn't need to fold it's doors. Yes it was an ugly loss but we had one of those last year and came within a d-back holding onto the football on an interception to beating the #4 ranked team at the time last season in week 3. These guys are still trying to play more consistent. Calm down people.
September 12th, 2011
10:09 am
Hey Southern fans, how bout you go to the Savannah times and troll the SSU coverage. This is an ATLANTA paper.
September 12th, 2011
11:07 am
Are all the people in the deep south this concerned about initials and who the real GSU is? This would make a great study for the rest of the country. KEEP it up! I am going to check in everyday to watch the back and forth. I am a believer. I wish I had a research grant. My friends at work said this was just sad..no way.. pure entertainment. The internet is awesome. I am exposed to a new host of cultural norms. Heck I might vacation down there and see a game? Where should a go? GSU Atlanta or GSU (the other place)? Recommendations?
September 12th, 2011
11:45 am
Penn CAA fan….Atlanta for entertainment, just dodge the homeless, or have plenty of one dollar bills handy. Statesboro, to see THE GSU Eagles play football. I'm not disrespecting the Atlanta school, this is their 2nd year? Good luck to them, I hope thay win every game, until they play the Eagles.
September 12th, 2011
12:08 pm
GSU-How about playing on the football field next to your baseball facility? The students do know they have a baseball complex don't they? It adjoins Georgia Perimeter College in Decatur. The next Atlanta four year school. If the Falcons lose one more game like they did in Chicago, the dome will be empty for them as well.


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|Good - 41 reviews
Welcome to Americas Best Value Inn Blytheville, conveniently located just off of northbound I-55, Exit 67. Blytheville, originally established as a lumber mill town, is now a steel production center and a gateway city to Arkansas, the "Natural State". Stay connected with free wireless high-speed Internet access in our guest rooms. Step into the privacy of yo...
Overall Rating - Good - 41 reviews
Okay 5.0
Convenience to the Interstate
Condition not good; in disrepairMissed wake up call; bathroom door in primer only with tag from lumber yard on jamb;
Excellent 10.0
It was clean!!!I have stayed at much more expensive places (La Quinta comes to mind) that were filthy, A/C not working right, hot tub was not hot etc. for a lot less money I got what I needed - a clean place to sleep.
|Okay - 13 reviews
The pet friendly Garden Inn Blytheville provides quality, affordable lodging in the city of Blytheville. Just 3 blocks from downtown, the Garden Inn is close to the Lucky Lady Casino and the Ritz Civic Center. Southeast Missouri State University is less than 30 miles, and the Big Lake State Wildlife Management Area is 20 miles from the Garden Inn. Hotel a...
Overall Rating - Okay - 13 reviews
|Excellent - 165 reviews
Our hotel in Blytheville, AR features two pools. At the pet-friendly Holiday Inn® hotel in Blytheville, AR, guests enjoy well-appointed accommodations and an entertaining array of amenities. Our location near I-55 makes it easy to access local attractions, nearby Blytheville Municipal Airport (HKA) and Arkansas International Airport (BYH). From playing a rou...
Overall Rating - Excellent - 165 reviews
Good 8.0
Nice place, clean, and comfortable. What more could you ask for!It was nice that the hotel had two pools.
Mediocre 3.0
the bed was soft
my toilet didn't work and neither did my iron in my roomthe staff was very important do not meet my expectations
|Okay - 49 reviews
Welcome to the Super 8 We have all Interior Corridors. We do not have an elevator and this why our upper floors are at a different cost. Pets allowed/We only accept under 25 lbs and the fee is 10.00 per pet per night. Outside Parking-Car and Pickup Truck Only Each room comes with Free High Speed Wireless Internet Access -ethernet cord is provided, Coffee...
Overall Rating - Okay - 49 reviews
Poor 1.0
Other than location nothing.
The hotel was old, dirty and smelly. The roof was falling off with patches of plastic tarps... overall the place was old and dirty. The first room we got was not cleaned and door was unlocked. The second room at least had clean towels.The should turn out the light on this motel. I am originally from the Blytheville area and I assure you the motel hasn't been updated in YEARS. The hotel is over priced for what it offers and my goodness this is 2014 and no elevator. We had to go up 3 flights of stairs to get to our second room we were given at check in because the first room was not cleaned and the door was propped open. It looked as if someone had just climbed out of the bed. The second room was dirty and the smell was nasty and it was a non-smoking room but not a non-moldy stale room. Really as I said before, don't leave the light on.. TURN IT OFF TURN IT OFF!
Mediocre 4.0
The staff tried to be helpful.
My first night there we helped clean the room due to trash on one of the tables and the bed looked like someone had laid on it.The hotel was poor in housekeeping, the air condition did not work and Manager was unresponsive to accommodate the minimum of expected comfort. The Staff did as much possible. I stayed 2 of the 3 nights and changed to a different hotel
|Okay - 21 reviews
With a stay at Deerfield Inn & Suites in Steele, you'll be within the region of Thunder Bayou Golf Links and Walker Park. This hotel is within the region of Hayti Pentecostal Holiness Church and Caruthersville Public Library. Make yourself at home in one of the 23 air-conditioned rooms featuring refrigerators and microwaves. Your room comes with a Tempur-Ped...
Overall Rating - Okay - 21 reviews
Poor 2.0
We checked in and got to the room and noticed dead bugs on the wall, something on the wall in the bathrrom behind the door and blue stuff all over the toliet. The shower needed cleaning.There was cereal on the floor also. We left the do not disturb sign on the door and they maid staff entered the room anyway twice second time messed with our belonging and then left note. DO NOT recommand. Also the manager complained about us useing a website.
Excellent 10.0
Rooms are clean and the English speaking staff very friendly and helpful. The desk clerk helped me set my laptop to access the internet, when I didnt know what to do. I didnt eat the breakfast, but the waffles smelled good. Great coffee. I will stay here again, when I come throuigh again.
|Excellent - 76 reviews
Blytheville, only five miles off the Mississippi River, combines small town living with the ease of interstate accessibility. Our community opens the door to the Arkansas River Valley and the Great River Road. The Hampton Inn® Blytheville hotel is located off I-55, minutes from the Industrial Park and historic downtown shopping. Blytheville area attractions...
Overall Rating - Excellent - 76 reviews
Excellent 9.0
Beautiful and clean.
Strange to get too because it is off a service road.
Excellent 9.0
Very clean, very nice. LOVED the beds!! Very comfortable!
The second floor vending machine ate two of my dollars! But the staff graciously returned my money to me.This was a very nice place to stop after a very long day on the road. I would highly recommend it. It was comfortable and relaxing.
|Good - 46 reviews
Located in Blytheville, Fairview Suites is in the historical district and close to Walker Park and Thunder Bayou Golf Links. This hotel is within the vicinity of Arkansas Northeastern College and Arkansas Aeroplex. Make yourself at home in one of the air-conditioned guestrooms. Complimentary wireless Internet access keeps you connected, and satellite program...
Overall Rating - Good - 46 reviews
Poor 1.0
Within 1-1/2 miles of the highway. You could see a good hotel across the street.
Horrible part of town. TV stand broken. Could see through the door. Other parts of the hotel room were dirty and broken. Bathroom floor tiling was incomplete. Towel rack above toilet broken and on the ground. Would not recommend this to anyone.
Poor 2.0
Bed was comfortable. Heat / air worked well
Low wattage lightbulbs. Dimly lit vanity and bathroom. Nasty looking couch I refused to sit in Very weak Wi Fi
|Excellent - 35 reviews
Deluxe continental breakfast 6:00am-9:00am. All rooms include wireless internet and micro/fridge. Hotel offers an exercise room, guest laundry, and a business center. Guest rooms with family suites and kids suites. We are a pet friendly hotel. Pet accommodation: 15.00 per stay. Limit 2 pets per room, 60 pounds maximum. Pets permitted in the designated pet fr...
Overall Rating - Excellent - 35 reviews
|Good - 88 reviews
Full service restaurant and lounge. Easy walk to movies, restaurants and convenience stores. Downtown and industrial parks 1 mile. Casino 25 miles. Memphis, TN 60 miles. Free continental breakfast. Pet Accommodation: 15.00/stay Max of 2 pets per room. Wireless Internet $60 deposit - refundable for equipment and software. Full service restaurant and lounge on...
Overall Rating - Good - 88 reviews
Mediocre 3.0
Not much...
Yes, the upholstered chair and stool in our room was filthy. There was grease or dark stains all over these pieces of furniture. ALSO, I GOT BEDBUG BITES, AND THEN IN THE SHOWER THERE WERE ALSO BUGS JUMPING AROUND IN THE SHOWER!?I WOULD NEVER GO THERE AGAIN EVER!
Poor 2.0
warm shower, comfortable bed, clean sheets and towels, take pets
I have a disturbing experience with the night clerk regarding my reservationI was moving from Texas to Illinois.My husband and I went in two cars and he was supposed to meet me an hour later. Blytheville is my halfway mark. I came in approximately 10:30 pm after driving 425 miles with four cats in the car. I had paid with a specific credit card that the front desk person said did not match the the one she said I used to make the reservation. I showed her my receipt and she insisted I had to show her the one I used to make my reservation and did not match anything in my wallet. She was going to turn me away late at night even though I showed her the receipt. I called Priceline from my cell phone. No landline was offered at the hotel maybe because I was obviously lying.The reception was poor with my cell phone and I was so frazzled my knees were beginning to buckle.It took a long ti...
|Okay - 101 reviews
Our Days Inn in Blytheville has all the comforts of home. We offer a free continental breakfast from 6-10AM every morning and free wireless internet. Later you can enjoy the various malls, shopping squares and retail stores for all your shopping needs. After a day in the city, spend a relaxing evening around our pool. For the dedicated television viewer we...
Overall Rating - Okay - 101 reviews
Good 8.0
They had remodel since we were there 2 years ago. We were very excited to see all that was done to the rooms and the cleanliness of the room. Thank you for making our stay very nice.
Poor 1.0
There was APSOLUTLY nothing I liked about this hotel .
Went inside hotel to confirm reservation and the manager told me he didnt have a contract w/Priceline and I had no room . I was stuck in the drive way due to current snow storm that was active . The manager told me he didn't care . I slept in the truckThat night . Was by far the worst experience . Them I called priceline and I can't even explain how much y'all didn't care either . NO CUSTOMER LOYALTY AT ALL !! Very disappointed . Not sure I will ever use either again
|Okay - 6 reviews
Overall Rating - Okay - 6 reviews
Mediocre 3.0
Not much... Location/Convenience
Cable TV went out. Tears in bedding. Staff wasn't helpful/friendly. AC/Heating unit was rigged with a clothes hanger (I'm assuming to keep it from rattling)We stayed at the Deerfield Inn in Blytheville after being forced off the highway due to weather. It was the first hotel we saw and pretty much our only option financially. I wound up booking on Priceline since it was less expensive than the price I was quoted at the desk. The girl at the front desk seemed stressed and I imagine that had mostly to due with having so many guests, but I'm pretty sure she didn't smile once and seemed pretty ticked that I went through Priceline. We get our room - I can only imagine that it was the King Nonsmoking Room I booked - but the door was broken and no one could get it open. She then moved us into another room - last one available I think. I asked if it was non-smoking, she said it was, but didn't want to guarantee an...


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Monday August 5, 2013 to Saturday August 17, 2013
Langston Hughes Exhibit with three drafts and final version of his poem, Cubes, is at the Oak Bluffs Library through August 17. Call 508-693-9433 for information.
Monday August 12, 2013
Hospice Summer Soiree Anniversary Party is tonight at Farm Neck Golf Club. Dinner by Jaime Hamlin and music by John Alaimo. Tickets are $125 per person. Visit hospiceofmv.org.
Pastimes Group Art Show of various mediums featuring Fran Dropkin, Nick Paciorek, Jeff P'an, Joan Rusitzky, Louisa Gould and John Holladay at the Louisa Gould Gallery, Main street in Vineyard Ha
Meditation on the Vineyard is from 8:30 to 9:30 a.m. at the bandstand at Ocean Park in Oak Bluffs. Bring your yoga mat.
Monday August 12, 2013
Watercolor Painting with John Holladay is from 9 a.m. to noon at Featherstone in Oak Bluffs. Cost is $50. Call 508-693-1850 or visit featherstoneart.org.
Drop-In Knitting group is from 9 to 11:30 a.m. at the Tisbury Senior Center, 34 Pine Tree Road in Vineyard Haven. Call 508-696-4205.
Monday August 12, 2013
Camp Terra Mare Pirates Week through August 16 is from 9 a.m. to 4 p.m. daily. Ages 5 to 16. Visit ymcamv.org.
A Walk Through Imagination is on display at the Polly Hill Arboretum, State Road in West Tisbury. Potter Bill O'Callahan and puppeteer Robin Tuck collaborate for magical landscape tour.
Monday August 12, 2013
Summer Soul Brunch Fundraiser is from 10 a.m. to 1 p.m. at 9 Oak Bluffs Avenue in Oak Bluffs. Speakers, music and raffle. Tickets are $100.


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After Treatment: The Needs of Cancer Survivors
A new report by the Institute of Medicine (IOM) concludes that a growing number of cancer patients are surviving the disease only to face a constellation of new needs and that too often these needs are not met. The 500-page report, based on an extensive review of the scientific literature and interviews with survivors, proposes recommendations for improving the care and quality of life for these individuals.
A primary recommendation is that all cancer patients be given summaries of their medical treatments and instructions for follow-up care once they complete therapy. These survivor care plans would document which treatments a patient had and which health changes should be monitored closely.
"A care plan is a concrete step that could be taken tomorrow and would provide relief essentially immediately," says Dr. Sheldon Greenfield, who directs the Center for Health Policy Research at the University of California, Irvine, and co-led the panel that produced the report, From Cancer Patient to Cancer Survivor: Lost in Transition. Read more
Guest Update by Dr. Ernie Hawk
TRWG Process Moving Forward, Members Named
Since being named by Dr. von Eschenbach earlier this year to chair the Translational Research Working Group (TRWG), I have come to more fully appreciate the potential of the working group to influence how we approach translational research. We will evaluate the translational research components of the National Cancer Institute's (NCI's) current portfolio and provide a blueprint for how best to harness our translational research resources. Our goal is to ensure that the processes and programs are in place at NCI to rapidly translate the scientific discoveries of the cancer community's many dedicated scientists into new interventions for preventing, diagnosing, and treating cancer.
There will be broad public input into the TRWG deliberations, including participation in the working group by many of the country's leading translational researchers, as well as representatives from the advocacy community, industry, the Food and Drug Administration (FDA), and NCI staff. In fact, the complete 60-member TRWG roster is now available on the working group's Web site at www.cancer.gov/trwg.
In naming the members, I worked with the TRWG co-chairs, Drs. Lynn Matrisian and William G. Nelson, to select as representative a group as possible, while still ensuring it was of a manageable size.
After Treatment: The Needs of Cancer Survivors
A new report by the Institute of Medicine (IOM) concludes that a growing number of cancer patients are surviving the disease only to face a constellation of new needs and that too often these needs are not met. The 500-page report, based on an extensive review of the scientific literature and interviews with survivors, proposes recommendations for improving the care and quality of life for these individuals.
A primary recommendation is that all cancer patients be given summaries of their medical treatments and instructions for follow-up care once they complete therapy. These survivor care plans would document which treatments a patient had and which health changes should be monitored closely.
"A care plan is a concrete step that could be taken tomorrow and would provide relief essentially immediately," says Dr. Sheldon Greenfield, who directs the Center for Health Policy Research at the University of California, Irvine, and co-led the panel that produced the report, From Cancer Patient to Cancer Survivor: Lost in Transition.
The study focuses on adult survivors from the time they complete initial treatment to a relapse, secondary illness, or death. During this period, survivors may develop any number of problems related to their cancers that prevents them from obtaining adequate health care, often with disastrous results.
The report stresses the need for more communication and coordination among doctors who treat the diverse health problems described in the report, including depression, sexual dysfunction, and heart disease.
The report also calls for the development of clinical care guidelines for every type of cancer, which would allow primary care physicians and other health professionals to help monitor and care for survivors.
"When you consider that there are 10 million cancer survivors in this country, finding these patients and delivering the best possible health care that is targeted to their special needs becomes a large concern for the health care community," says Dr. Sandra Horning, president of the American Society of Clinical Oncology (ASCO).
"I don't believe the issues of cancer survivorship have ever been laid out as clearly and comprehensively as in this report," adds Dr. Horning. ASCO is hosting a conference today to discuss the report and plan strategies for implementing the recommendations.
The study follows a report on survivors by the President's Cancer Panel last year, which proposed survivor care plans, and a 2003 IOM study on childhood cancer survivors.
All cancer survivors, the report concludes, have permanent health conditions that may need to be treated like other chronic conditions. But it is not uncommon for friends and relatives of survivors to suggest that normal life should resume once the treatments have ended.
"This idea that a person completes cancer treatment and then returns to normal life as though nothing had happened is outrageous," says one of the report's editors Ellen Stovall, who is president of the National Coalition for Cancer Survivorship and one of several survivors on the panel.
The panel emphasized the importance of more research to develop evidence-based survivorship interventions for meeting the unique needs of cancer survivors.
"More people today are living with cancer than dying from it, and we must look critically at issues of quality of life and care for these survivors," says Dr. Julia Rowland, director of NCI's Office of Cancer Survivorship. "This report is a powerful blueprint for action."
By Edward R. Winstead
Guest Update by Dr. Ernie Hawk
TRWG Process Moving Forward, Members Named
Since being named by Dr. von Eschenbach earlier this year to chair the Translational Research Working Group (TRWG), I have come to more fully appreciate the potential of the working group to influence how we approach translational research. We will evaluate the translational research components of the National Cancer Institute's (NCI's) current portfolio and provide a blueprint for how best to harness our translational research resources. Our goal is to ensure that the processes and programs are in place at NCI to rapidly translate the scientific discoveries of the cancer community's many dedicated scientists into new interventions for preventing, diagnosing, and treating cancer.
There will be broad public input into the TRWG deliberations, including participation in the working group by many of the country's leading translational researchers, as well as representatives from the advocacy community, industry, the Food and Drug Administration (FDA), and NCI staff. In fact, the complete 60-member TRWG roster is now available on the working group's Web site at www.cancer.gov/trwg.
In naming the members, I worked with the TRWG co-chairs, Drs. Lynn Matrisian and William G. Nelson, to select as representative a group as possible, while still ensuring it was of a manageable size.
Following in the mold of the Clinical Trials Working Group, TRWG will formulate recommendations for developing an optimized model for a translational research program, as well as an implementation plan for taking those recommended actions. The implementation plan is important because it will lay out the short-term changes to existing programs the working group believes are needed, as well as what new, longer term initiatives are required. Both the recommendations and the implementation plan will be presented to the National Cancer Advisory Board.
In December, TRWG will have its first planning meeting, which will be preceded by small-group teleconferences where members can engage in preliminary discussions about the issues that need to be addressed and potential models for a comprehensive translational research program.
The TRWG Web site will be an excellent resource for the cancer community to use for following and commenting on the TRWG process. After the December planning meeting, for example, specific questions about issues raised during the meeting will be posted to the Web site, and the public will be invited to submit comments on them.
In February, a larger roundtable meeting will be held involving the entire TRWG and an additional 140 participants, most of whom will be nominated by TRWG members. The February meeting should allow for a robust and fruitful discussion of the issues and potential models raised during the first planning meeting and public comment period.
I encourage those with an interest in the process to participate by submitting comments when materials are posted on the TRWG Web site. If you have questions about the TRWG, they can be submitted via the Web site as well.
I'm excited about TRWG and confident that the process for developing its recommendations and implementation plan will lead to important changes that, first and foremost, will benefit patients and move NCI and the cancer community closer to the 2015 goal.
Consortium Modelers Interpret U.S. Trends in Breast Cancer Mortality
Do screening mammography and adjuvant therapy really reduce breast cancer mortality outside of clinical trials? While the benefits of therapy are more clear, a unique consortium of seven biostatistical teams has added important evidence to address the still controversial question regarding mammography. The problem of separating out the impact of mammography and advances in therapy, which occurred at about the same time during the 1980s and 1990s, was addressed by the consortium in their study reported in the October 27 New England Journal of Medicine.
This approach used population data to describe the dissemination and usage patterns of mammography and adjuvant therapy that occurred over time in the United States. The usage patterns were then coupled with seven independent modelers' synthesis of all available information on the benefits of these advances. The authors make the case that each factor accounted for half of the historic 24 percent decrease in mortality that was actually observed between 1990 and 2000.
Until now, the debate over mammography included many who questioned the evidence that screening does in fact reduce cancer deaths, one of them being lead author Dr. Donald Berry, head of biostatistics at the University of Texas M.D. Anderson Cancer Center. "The controlled trials on which the mortality assertion was based were uneven and not without flaws," he says.
Nonetheless, citing more recent papers, screening advocates have said that mammography can reduce mortality by up to 69 percent. But, says Dr. Berry, "Fervor doesn't substitute for evidence. Here we brought the pieces of evidence together in a novel way and separated the effects of screening and treatment. I would say the question is now at least 95 percent settled, in favor of mammography reducing breast cancer mortality."
"The ability to come at important questions like this in a unique way was part of the motivation when NCI formed the Cancer Intervention and Surveillance Modeling Network (CISNET) in 2000," says project director Dr. Eric J. Feuer, chief of NCI's Statistical Research and Applications Branch, who is also one of the study's 10 authors.
The CISNET approach includes bringing together distinct teams - including some of the leading biostatistical investigators in the cancer community - with an interest and expertise in a particular cancer site, framing a common problem, and letting each team develop its own independent model of how to solve it. The network also includes grantee teams that specialize in lung, prostate, and colorectal cancers.
"All models agreed that both screening and treatment reduced breast cancer mortality, and that the observed reduction in the actual population - 24 percent during the 1990s - could not be attributed to either one acting alone," says Dr. Kathy Cronin, a mathematical statistician who helped develop the common assumptions all teams used. Just under half of the combined effect came from screening. "There will never be a final piece of evidence on such a complex and tangled question, but this result provides additional evidence for mammography's role in the undeniable progress seen during the 1990s," she adds. "The study also helped refine the population mortality impact of important treatment advances in the use of multiagent chemotherapy and tamoxifen."
The proportion of the total reduction in the death rates from breast cancer attributed to screening varied in the seven models from 28 to 65 percent (with a median of 46 percent), with adjuvant therapy contributing the rest. The variability across models in the absolute contribution of screening was larger than it was for treatment, reflecting the greater uncertainty associated with estimating the benefit of screening.
"Comparative modeling yields a powerful outcome," explains Dr. Feuer, "because you actually produce a meta-result that no single group could achieve. This is a testament not only to the intellectual rigor used to build each of the models, but to the scientists' willingness to collaborate and cooperate."
Links to the journal and more study details can be found at http://cisnet.cancer.gov/.
By Addison Greenwood
Current medical care provides accurate and economical methods for the detection of cervical cancer and effective removal of precancerous cervical lesions. But standard cervical cancer screening and treatment require several clinic visits over the course of many months, an unfeasible approach for women in underserved, limited-resource communities.
A clinical trial reported in the November 2 Journal of the American Medical Association (JAMA) attempted to increase cervical cancer prevention in an underserved population by using a single-visit approach to screening and treatment. Trial participants in California were randomized to either a standard-care or single-visit group. Women in the standard-care group received a conventional Pap test and were immediately discharged home; those with abnormal results were contacted by telephone and urged to return for follow-up. Women in the single-visit group remained in the clinic until their tests were processed, and those with high-grade lesions were offered immediate cervical loop electrosurgical excision. A significantly greater number of women with high-grade lesions in the single-visit group (88 percent) received definitive treatment within 6 months than did women in the standard-care group (53 percent).
A second study reported in the same issue of JAMA tested a noncytology-based screen-and-treat approach in the extremely limited-resource setting of Khayelitsha, South Africa. All participants underwent visual inspection of the cervix with acetic acid (VIA) and human papillomavirus (HPV) DNA testing; 2 to 6 days later, they were randomized to receive treatment based on VIA results, treatment based on HPV DNA results, or delayed evaluation. Women in the VIA and HPV DNA groups with positive test results were immediately offered cryotherapy. Follow-up rates did not differ significantly between groups, but prevalence of high-grade cervical intraepithelial neoplasia and cancer at 6 months were significantly less in both the VIA (2.23 percent) and HPV DNA (0.80 percent) groups compared with the control group (3.55 percent).
In both studies, treatment was offered without definitive diagnosis. But given the very low risk of the interventions and the high likelihood of patients with cervical neoplasia being lost to follow-up, the authors of both studies concluded that these programs are a practical and feasible way to reduce the prevalence of high-grade precancerous cervical lesions in underserved populations.
Study Shows How 1G8 Antibody Inhibits Prostate Cancer
Prostate stem cell antigen (PSCA) is a cell-surface protein found in most prostate cancers, as well as bladder and pancreatic cancer. The level of this antigen's expression correlates directly with prostate cancer severity and inversely with its prognosis. Researchers from UCLA's Jonsson Comprehensive Cancer Center have already shown that an antibody against PSCA - 1G8, which they developed - inhibits tumor growth and metastasis, and improves survival in mice. Now they have characterized the molecular pathways through which the antibody works, publishing their findings in the October 15 Cancer Research.
The team inserted a PSCA expression vector into prostate cancer cells and incubated them in the presence of 1G8. What resulted were weakened plasma membranes, broken nuclei, DNA leakage, and an overall flattened appearance of the cells. However, the cells did not show the usual signs of apoptosis, including chromatin condensation and degradation. When the team tested fragments of the antibody, they found that the full protein and a bivalent (but not monovalent) fragment could induce cell death. Both the bivalent fragment and the full 1G8 antibody slowed tumor growth in mice. The authors concluded that 1G8 acts through a direct antigen cross-linking mechanism that is independent of caspases and of the antibody's cell-attaching Fc domain.
Though these results come from in vitro and mouse studies, they have implications for clinical therapy. "In particular," the authors noted, "knowledge of the mechanism…may affect antibody selection, timing of therapy, therapeutic setting, or rational selection of agents for combination therapy."
Studies Point to Anticancer Potential of Broccoli Sprouts
A chemical in broccoli sprouts may be able to prevent two very different cancers, according to the results of studies presented last week at the American Association for Cancer Research (AACR) "Frontiers in Cancer Prevention Research" meeting. Researchers from Japan reported that people infected with the bacteria H. pylori - which has been associated in several studies with gastric cancer - and who ate the sprouts daily for 2 months had reduced levels of H. pylori and pepsinogen (a biomarker of gastritis), compared with those who ate alfalfa sprouts for the same period.
While they are virtually identical chemically, broccoli sprouts contain high levels of sulforaphane, while alfalfa sprouts contain none. Two months after the study ended, subjects in the broccoli sprout group saw their H. pylori and pepsinogen levels return to baseline. The researchers attributed the broccoli sprouts' benefit to the protective effect of sulforaphane against cell DNA damage.
To confirm whether the sprouts do indeed have an anticancer effect, the study's leader, Dr. Akinori Yanaka, said during a news conference that his lab hopes to test the intervention over a longer period to see if it can prevent gastric cancer recurrence in those at high risk.
Also at the AACR meeting, researchers from Johns Hopkins University reported that, in a mouse model of UV-light-induced melanoma, sulforaphane extract applied to the skin significantly reduced the risk of cancerous skin tumors. All of the control mice developed cancerous skin tumors, whereas only half of the mice who received a high dose of the extract did. The high-dose mice that developed tumors had their tumor burden reduced by half.
Familial Cancer Risk Estimates Affected by Surveillance Bias
The risk of familial cancer after a parent or sibling is first diagnosed with cancer may be overestimated based on the number of additional cancers found among other family members shortly after the initial diagnosis, according to a study in the November 2 Journal of the National Cancer Institute.
Researchers from the German Cancer Research Centre in Heidelberg followed almost 1.7 million offspring and siblings of 846,448 cancer patients in the Swedish Family Cancer Database. They compared the relative risk of those family members against the general population for developing cancers of the breast, prostate, and cervix, as well as other cancers. For most of the cancers, the relative risk for family members was greatest in the first year but "decreased with time after diagnosis of the first familial tumor," the researchers reported. For example, "daughters of women with breast cancer had a statistically significantly higher relative risk of in situ breast cancer during the year of the mother's diagnosis than they did 5 or more years later," the study found.
The diagnosis of cancer in a family raises concern among the patient's relatives, who may seek medical advice in the immediate aftermath of the initial bad news, resulting in increased detection of asymptomatic tumors - a phenomenon called surveillance bias.
Given the possibility of inflated risk estimates, the scientists cautioned that "the possibility of overestimated familial risks of cancer shortly after diagnosis of the first familial tumor should be considered before a patient's clinical and genetic counseling is implemented."
National Study Shows Relationship of Movies to Kids' Smoking
A new study by researchers at Dartmouth Medical School found that young people who watched the most smoking in the movies were almost three times more likely to start smoking than their peers who watched the least amount of smoking in movies. This result was found throughout all regions of the country, regardless of race and ethnic group. The results of this NCI-funded study were published in the November 7 Journal of Pediatrics.
The researchers surveyed a total of 6,522 adolescents aged 10 to 14 from across the country using a random-digit telephone dial system. The participants were representative of the U.S. population of adolescents in terms of age, sex, household income, and census region. Using a telephone keypad, respondents indicated which movies they had seen out of 50 that had been randomly selected from among the top 532 U.S. box office hits between 1998 and April of 2003 (74 percent of which included smoking).
The study showed that exposure to onscreen smoking was an independent, primary risk factor even after accounting for the impact of other known risk factors for smoking such as parental and sibling smoking, smoking by friends, and rebelliousness, among other factors.
Name of the Trial
Principal Investigator
Why Is This Trial Important?
In this trial, researchers are studying 17-DMAG, an HSP-90 inhibitor developed by NCI, to see if it can help prevent cancer cells from growing in patients with solid tumors or lymphomas. The trial will also be used to determine the maximum dose of 17-DMAG that can be given to patients and examine what side effects the drug may cause.
"Preclinical research results suggest that inhibiting HSP-90 will alter many of the protein pathways in tumor cells and may result in tumor cell death," said Dr. Gutierrez. "This is the first test of 17-DMAG in humans, and so far, the drug has been well tolerated.
"We think that 17-DMAG's mode of action may represent an important new approach in the treatment of many types of cancer."
Who Can Join This Trial?
Where Is This Trial Taking Place?
Contact Information
An archive of "Featured Clinical Trial" columns is available at http://cancer.gov/clinicaltrials/ft-all-featured-trials.
Buetow Named to New NCI Position
Dr. Buetow will manage and execute information technology and bioinformatics initiatives that will lead to the usage of common tools, standards, and datasets across NCI; assist internal teams in adopting and leveraging NCI's cancer Biomedical Informatics Grid™ (caBIG™) infrastructure; review and update NCI's existing and planned bioinformatics programs and activities; make recommendations for the creation of a standing group that will provide technical guidance on new projects; and regularly report to the NCI Executive Committee, of which he is a member.
NCI Announces Biorepository Coordination System
The Biorepository Coordination System (BCS) will link researchers at 11 institutions to enable and accelerate the evaluation of key genes and proteins as potential clinical measures of prostate cancer. The project will create a common biorepository of high-quality, clinically annotated biospecimens, including paraffin-embedded and frozen tissue, serum, and plasma. Researchers will gain the analytical power of combined biorepository resources that will support an Inter-Prostate SPORE Biomarkers Study. This study will provide a scientific framework for testing the BCS model by conducting validation trials on promising prostate cancer prognostic biomarkers.
For more information, visit http://prostatenbnpilot.nci.nih.gov.
Science Writers' Seminar Focuses on Pain
DCCPS Report Available Online
CGEMS Funding Opportunity Available
The FDA last week approved drugs for pancreatic cancer and a rare form of leukemia that affects both adults and children.
The agency approved erlotinib (Tarceva), in combination with gemcitabine, as a first-line treatment for patients with advanced, inoperable, or metastatic pancreatic cancer. The approval was based on a single phase III randomized clinical trial in which the combination of erlotinib, an EGFR-inhibitor approved approximately a year ago for the treatment of non-small-cell lung cancer, and gemcitabine, the standard treatment for these patients, resulted in a small but statistically significant improvement in survival compared with gemcitabine alone. The median improvement in survival was only 12.8 days, but the 1-year survival rates favored the addition of erlotinib, 24 percent versus 17 percent.
During a meeting in September, the FDA Oncology Drugs Advisory Committee voted in favor of approving erlotinib for this new indication. Committee members struggled with whether such a small survival improvement - which could be accompanied by an increase in diarrhea and skin rash - was enough to justify an approval recommendation. In the end, most committee members agreed, as one put it, that the approval would be an important "first step" toward new options for what is an almost uniformly fatal form of cancer.
The agency also approved nelarabine (Arranon) to treat adults and children with T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), and whose disease is refractory to or has relapsed following at least two chemotherapy regimens. Nelarabine, which was approved under an accelerated approval mechanism and also granted orphan drug status, is the first drug cleared for this rare indication; an estimated 500 patients per year have relapsed or refractory disease.
FDA based the accelerated approval - which requires the drug's manufacturer, GlaxoSmithKline, to conduct additional studies to verify clinical benefit - on two NCI-sponsored phase II clinical trials. The nelarabine phase II trial in children was conducted by the Children's Oncology Group (COG), while the trial in adults was led by the Cancer and Leukemia Group B, in conjunction with the Southwest Oncology Group. In both trials, complete responses were observed in approximately 20 percent of patients. Median overall survival was 21 weeks in adults and 13 weeks in children. The post-approval study will be an NCI-sponsored phase III trial conducted by COG and will include event-free survival at 4 years as an endpoint.
"It is very important to now have this drug available," said Dr. Kimberly P. Dunsmore, associate professor of pediatrics at the University of Virginia Health System. "It's proven to be quite effective in the phase I and II settings." Nelarabine's effectiveness in the trials to date is welcome, she adds, because patients have typically been refractory to other drugs tested for this indication.
Dr. Dunsmore is the principal investigator for a COG-conducted pilot study testing nelarabine upfront in patients with T-ALL or T-LBL who are at increased risk for relapse. The trial recently closed to accrual.


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Alkalosis is a condition in which the body fluids have excess base (alkali). This is the opposite of excess acid (acidosis).
Causes, incidence, and risk factors
The kidneys and lungs maintain the proper balance of chemicals, called acids and bases, in the body. Decreased carbon dioxide (an acid) or increased bicarbonate (a base) levels make the body too alkaline, a condition called alkalosis.
Respiratory alkalosis is caused by low carbon dioxide levels in the blood. This can be due to:
- Fever
- Being at a high altitude
- Lack of oxygen
- Liver disease
- Lung disease, which causes you to breathe faster (hyperventilate)
- Salicylate poisoning
Metabolic alkalosis is caused by too much bicarbonate in the blood.
Hypochloremic alkalosis is caused by an extreme lack or loss of chloride, which can occur with prolonged vomiting.
Hypokalemic alkalosis is caused by the kidneys' response to an extreme lack or loss of potassium, which can occur when people take certain diuretic medications.
Compensated alkalosis occurs when the body returns the acid - base balance to normal in cases of alkalosis, but bicarbonate and carbon dioxide levels remain abnormal.
- Confusion (can progress to stupor or coma)
- Hand tremor
- Lightheadedness
- Muscle twitching
- Nausea, vomiting
- Numbness or tingling in the face or extremities
- Prolonged muscle spasms (tetany)
Signs and tests
An arterial blood gas analysis or basic metabolic panel will confirm alkalosis and determine if it is a respiratory alkalosis or a metabolic alkalosis. Other tests may be needed to determine the cause of the alkalosis. These may include:
- Litmus paper (urine dipstick tests)
- Urinalysis
- Urine pH
Treatment of alkalosis depends on finding the specific cause.
For alkalosis caused by hyperventilation, breathing into a paper bag causes you to retain more carbon dioxide and improves the alkalosis. If your oxygen level is low, you may receive oxygen to help the alkalosis.
Some people need medications to correct chemical loss (such as chloride and potassium). Your health care provider will monitor your vital signs (temperature, pulse, rate of breathing, blood pressure).
Expectations (prognosis)
Most cases of alkalosis respond well to treatment.
- Arrhythmias
- Coma
- Electrolyte imbalance (such as hypokalemia)
Calling your health care provider
Call your health care provider if you become confused, unable to concentrate, or unable to "catch your breath."
A visit to the emergency room or call to the local emergency number (such as 911) is warranted for:
- Loss of consciousness
- Rapidly worsening symptoms of alkalosis
- Seizures
- Severe breathing difficulties
Prevention depends on the cause of the alkalosis. Normally, people with healthy kidneys and lungs do not have significant alkalosis.
Seifter JL. Acid-base disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 119.
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.


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|Zumba Fitness
Event Type: Morley Library Special Event
Date: 4/13/2013
Start Time: 2:00 PM
End Time: 3:00 PM
Come Join the Party with Zumba instructor, Annette Tufts! Annette says: "Zumba is a great way to meet new people, burn calories and work up a sweat! It's the most fun I have ever had exercising. Best part is that it doesn't feel like exercise it's more like getting together with your best friends for an hour of dancing! Don't worry if you aren't familiar with Latin style dancing...just follow my lead and you will catch on in no time. So put on some comfortable sneakers, grab a water bottle and get ready to whittle away your muffin top, strengthen your core and tone your legs."
Location: Combined Meeting Room A and B
Registration Ends: 4/12/2013 at 6:00 PM
Presenter: Annette Tufts
Status: Closed
|Please Note
We're sorry. The registration deadline was 4/12/2013 at 6:00 PM.


text: this one was dated back on august 9th where i got so restless waiting for the national parade to start that i decided to skip it all and urged mom & kunnie to meet sam & cliff at relish for dinner. i went for their breakfast menu this time round & ordered their eggs benedict - which i thereafter imposed an abstinence on because the eggyness really killed the dish in a bad way. i recommended the carbonara pasta to my mom & sam & a burger to kunnie which were all devoured heartily. naturally, a night spent out at serangoon gardens will result in a conclusion at udders for their super tasty waffles + ice-cream. i got up & did a commemorative (massive) scribble on the walls of udders as i was proud to be out of the house on national day. Full Photoset: http://on.fb.me/n2Eoc4 Relish: http://www.wildrocket.com.sg/relish.htmUdders: http://www.udders.com.sg


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From Wealth to PowerPrinceton University Press 1999; US$ 32.95
What turns rich nations into great powers? How do wealthy countries begin extending their influence abroad? These questions are vital to understanding one of the most important sources of instability in international politics: the emergence of a new power. In From Wealth to Power , Fareed Zakaria seeks to answer these questions by examining the most... more...
The Post-American WorldPenguin Books Ltd 2009; Not Available
The growth of countries such as India, China, Brazil, Russia, South Africa and Kenya is generating a new landscape. The tallest buildings, biggest dams, highest-grossing movies and most advanced mobile phones are now all being made outside Europe and the United States. Countries that previously lacked polotical confidence and national pride are finding... more...
Does the 21st Century Belong to China?House of Anansi Press 2011; US$ 12.95
Is China?s rise unstoppable? Powered by the human capital of 1.3 billion citizens, the latest technological advances, and a comparatively efficient system of state-directed capitalism, China seems poised to become the global superpower this century. But the Middle Kingdom also faces a series of challenges. From energy scarcity to environmental degradation... more...
Can the World Tolerate an Iran with Nuclear Weapons?House of Anansi Press 2013; US$ 12.95
In this edition of the Munk Debates, four of the world?s leading thinkers square off to debate one of the most important geopolitical issues of the time: are Iran?s nuclear ambitions a global threat? The Munk Debates are Canada?s premier public policy event. Held semi-annually, the debates provide leading thinkers with a global forum to discuss the... more...
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Eleni Petroulaki
Eleni Petroulaki-Ivic, born in Sitia Crete, is one of Greece's most notable fitness personalities. From a young age, Eleni has been involved in Fitness. At the age of 8, she started collecting sporting achievements both in Greece and abroad and has not stopped. In 1992, she was the first Greek fitness instructor to launch a series of tapes and DVDs, which included her exercise program, Total Body Conditioning (TBC). Eleni, also sometimes referred to as the Greek Yoga Goddess, was the first to introduce Power Yoga to Greece. In 2002 she founded the health club ASANA. Today there are 8 ASANAS throughout Greece.
Eleni's Vitals
|Professional Yoga Instructor
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|Dari Lullaby by Thor
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|Power Yoga


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RHINELANDER, WI (WSAU) - Bad weather delayed court actions around the state, including a ruling about the wof hunt, and sentencing for two Vilas County men.
52-year-old Bruce Jacobsen is the Rhinelander doctor convicted of having child pornography on his computer. Due to the storm, Oneida County court officials will try again to sentence him on Valentines Day at 9:00 a.m.
81-year-old Elmer Goetsch of Three Lakes now admits to recording nude movies of interns working in his house. Goetsch was to enter a plea and be sentenced yesterday, but his sentencing will now be February 14th at 1:30 p.m.
In Madison, Judge Peter Anderson was to issue an oral ruling on the use of dogs for wolf hunting. It now appears hunting quotas will be reached and the season will finish before Anderson issues the ruling January 4th.


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Johnson Controls investors in a tight spot
The company has a great long-term story, but its building energy business has hurt the overall picture.
You might think that the problem with Johnson Controls (JCI) was its exposure to the auto industry -- especially the auto industry in China, where the company has a 45% share of the auto-seating market. After all, auto sales are slowing in China, and European auto sales didn't exactly zoom ahead in 2011. Or in the auto battery business, which is exposed to, you guessed it, any slowdown in auto sales.
But, no, the problem for nine of the last 10 quarters has been in the building energy systems segment. In the December 2011 quarter -- the first quarter of the company's fiscal year -- revenue growth in the building energy segment came in at 3%. That well below the projected 7% growth for the segment. Operating profit was about 20% below forecast and margins were also below forecast.
The problems with the building energy systems segment have meant that Johnson Controls has badly underperformed purer-play auto suppliers such as BorgWarner (BWA). Shares of BorgWarner are up more than 23% this year. Shares of Johnson Controls are up 1.6%.
And I think Johnson Controls is likely to get hit by underperformance in its building energy systems segment again when it reports fiscal second-quarter earnings on April 20. Johnson Controls didn't use the last quarter to cut its forecast for the building energy systems unit to the bone in order to engineer the chance for a positive earnings surprise. Instead, the company held to its target for the business and continued to look for margins for 2012 to improve by 0.5 to 0.7 percentage points over 2011. That seems really unlikely, since the company was already behind the 2011 pace at the end of the first fiscal quarter.
In other words, there's a good chance that Johnson Controls will disappoint again when it reports fiscal second quarter earnings on April 20. (For the first quarter, the company reported earnings of 60 cents a share, 2 cents a share below analyst projections.)
So what do you do if you continue to like the company's long-term story, as I do, but are frustrated by the way the continued negative surprises from the building energy systems business have negated the company's strengths in auto interiors and batteries? (The stock is a member of my long-term Jubak Picks 50 portfolio on the strength of that long-term story.) Unfortunately, it's also a member of my 12-18 month Jubak's Picks portfolio, where it's done nothing good since 2010. The shares fell 16.4% in 2011. Fortunately, I bought in September 2009 so I caught part of the 52.9% gain in 2009 and the 42.3% gain in 2010.
But that's ancient history. What do you do now?
The stock is cheap at a trailing 12-month price-to-earnings ratio of 11.49. The Wall Street consensus is that Johnson Controls will show earnings growth of 14.6% in fiscal 2012 (despite its building energy systems problem.) Bloomberg calculates the company's enterprise value at $27.8 billion, but the stock market gives it a market cap of just $21.6 billion.
If you don't own the stock, I'd certainly wait at least until after earnings on April 20 before thinking about buying. The March quarter is likely to be a stinker -- Wall Street estimates a 5.8% earnings decline from the March quarter of 2011 and, given Johnson Controls' recent history, an earnings miss isn't out of the question.
But if the shares do fall further or even stay near the recent range of $31 to $33 a share, I'd certainly step up with some buying. The consensus for the June quarter calls for earnings growth of 32.8%. (Watch the April 20 conference call to see if Johnson Controls cuts its guidance for the second half of fiscal 2012.) For fiscal 2012, Wall Street is looking for earnings growth of 14.6% and then for 22.6% in fiscal 2013.
If you already hold the stock, I don't think there's much point in selling now in order to rebuy in a month or two or three in the hope of making a couple of bucks on the trade. You've hung in so far and, although I suspect Johnson Controls will disappoint on April 20, I think most of that disappointment is in the stock price.
I'd certainly cut my last and wildly optimistic target price of $55 by March 2012. But I think $44 a share by April 2013 is certainly reasonable, especially if the U.S. commercial real estate market recovers -- and U.S. auto sales continue to climb -- with a gradually strengthening U.S. economy.
Copyright © 2014 Microsoft. All rights reserved.
Fundamental company data and historical chart data provided by Morningstar Inc. Real-time index quotes and delayed quotes supplied by Morningstar Inc. Quotes delayed by up to 15 minutes, except where indicated otherwise. Fund summary, fund performance and dividend data provided by Morningstar Inc. Analyst recommendations provided by Zacks Investment Research. StockScouter data provided by Verus Analytics. IPO data provided by Hoover's Inc. Index membership data provided by Morningstar Inc.
Fed keeps important 'considerable time' language in reference to short-term interest rates, but dissents and dots leave doubts.
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Other Cobalt Reviews
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The community thinks...
Excellent buy. by Joe from Boston on 12/22/2008. Trim: 2008 Chevrolet Cobalt LT1 Coupe, Owned less than 1 year.
Pros: Economical to own. Minimal maintenance.
Cons: Small trunk opening. Trunk is spacious but opening should be bigger to get suitcases & boxes in & out.
Overall review: Vehicle runs very well, very efficient on gas & oil. Highly recommend to anyone looking for economy. Very competitive with small foreign economy cars. I prefer to buy American.
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- Continuing Diagnostics and Mitigation: Discussion of Progress and Next Steps
- Federal Executive Forum
- Federal Tech Talk
- The Future of Government Data Centers
- The Future of IT: How CIOs Can Enable the Service-Oriented Enterprise
- The Intersection: Where Technology Meets Transformation
- Maximizing ROI Through Data Center Consolidation
- Mitigating Insider Threats in Virtual & Cloud Environments
- Modern Mission Critical Series
- Moving to the Cloud. What's the best approach for me
- Navigating Tough Choices in Government Cloud Computing
- The New Generation of Database
- Satellite Communications: Acquiring SATCOM in Tight Times
- Targeting Advanced Threats: Proven Methods from Detection through Remediation
- Transformative Technology: Desktop Virtualization in Government
- The Truth About IT Opex and Software Defined Networking
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OPM: FSA participants can rollover $500 in unused funds
Feds participating in the Federal Flexible Spending Account Program will now be able to rollover up to $500 from one year to the next in unspent funds from their limited expense and health care flexible spending accounts.
Tags: OPM , FSA , FSAFEDS , pay and benefits , Katherine Archuleta , Ben Cardin , Barbara Mikulski , Mark Warner , Tim Kaine , Michael OConnell
OMB, OSTP to release new tools to reach big open data goals
The Office of Management and Budget and the Office of Science and Technology Policy are on track to launch a new metadata validator tool this month. They are also developing an integrated dashboard that will track agency progress on the administration's open data goals.
Tags: OMB , shared services , management , technology , financial management , Performance.gov , Stephanie Wasko , human resources management , cross-agency goals
Shared service providers preparing for more, bigger agencies
The Obama administration looks to expand shared service usage even more by improving existing financial shared service providers and laying the groundwork for shared service governance.
Tags: OMB , shared services , management , technology , Performance.gov , Stephanie Wasko , financial management , human resources management , cross-agency goals
Treasury CIO East to retire in June
Robyn East confirms she will leave after three years on the job.
Tags: Robyn East , people , Mike Parker , technology , Jason Miller
Treasury begins shared services quest to educate, integrate
The Office of Financial Innovation and Transformation issued two RFIs in the last few weeks. One announced an industry day for May 21, and the other is looking for ideas to improve how the government manages and integrates data from different systems.
Tags: management , financial management , OMB , Joe Ward , Interior , HHS , Jason Miller , Bill McCabe , Government Performance Summit , Beth Angerman , The Performance Institute , Mark Reger , shared services , the Association of Government Accountants
USDA joins the ranks of the financial shared services providers
The Office of Management and Budget and the Treasury Department Friday announced they recertified the departments of Interior, Treasury and Transportation and added USDA to be the support pylons of its financial management shared services initiative. GSA is no longer an approved provider, and it's unclear where its 44 customers will migrate to next.
Tags: financial management , OMB , Beth Cobert , Dick Gregg , USDA , GSA , Jason Miller
Treasury figuring out how the shared services pieces fit into governmentwide puzzle
In part 3 of our special report, Shared Services Revisited, Federal News Radio explores the administration's plans to ensure success in consolidating and standardizing financial systems this time around. Beth Angerman, director of Treasury's Office of Financial Innovation and Transformation (OFIT), said the goal is creating a repeatable, sustainable process for agencies to move to federal financial management providers. Over the next six months, Treasury and OMB must answer many of the outstanding questions about how this initiative will truly work.
Tags: technology , financial management , Shared Services Revisited , OMB , Sylvia Burwell , Beth Angerman , Carlos Otal , Grant Thornton , Association of Government Accountants , Jason Miller
Financial management providers ill-equipped to take on large customers
In our special report, Shared Services Revisited, OMB still must solve long-standing challenges to ensure federal providers are capable of bringing on large, cabinet level agencies. The role of the private sector is leaving some vendors unhappy, but officials say history shows their success rate with financial management system implementation to be poor.
Tags: management , financial management , Shared Services Revisited , OMB , Norman Dong , Beth Angerman , Lisa Kazor , Savantage , Reid Jackson , Compusearch , Kevin Greer , Accenture , Joe Ward , Interior Business Center , Jason Miller
Familiar questions, few answers so far for OMB's latest financial systems effort
In part 1 of Federal News Radio's special report, this second attempt by OMB to move agencies to financial management shared services is fraught with the same obstacles of a decade ago. But OMB believes this attempt at shared services is different. The administration says budget concerns and technology advancements will help overcome these long-standing barriers.
Tags: management , technology , shared services , Beth Angerman , OMB , Norman Dong , GSA , Lisa Kazor , Oracle , Reid Jackson , Carlos Otal , Grant Thornton , financial management , Jason Miller , Shared Services Revisited , Aaron Cornfeld
Inside the Reporter's Notebook: DoD taking own path with cloud security, Treasury's Reger joins OMB
In this week's Inside the Reporter's Notebook, Executive Editor Jason Miller explores how DoD is developing its cloud security standards and Treasury is filling a financial management void.
Tags: Teri Takai , FedRAMP , GSA , DoD , Keith Alexander , Edward Snowden , cloud , cybersecurity , Mike Rogers , Robert Work , Mark Reger , Danny Werfel , Norman Dong , OMB , Anne Rung , Dennis VanderTuig , Dan Gordon , OFPP , Lesley Field , Jason Miller , Inside the Reporters Notebook


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Ongoing Projects
Here is an overview of some of the projects the Town is working on. Click on any link below to jump to a more detailed description of the project.
Route 13/Emerson Road/Armory Road Intersection Improvements
The Town was awarded $360,000 in federal Congestion Mitigation and Air Quality (CMAQ) grant funding which combined with $90,000 approved as local matching requirements will be applied to signalization and left-turning lane improvements at this congested intersection.
Intersection and Signalization Project: Project Overview
Brox Properties
In 2000 The Town made a valuable long-term investment in the acquisition of 270 acres commonly referred to as 'the BROX Property'. The land serves to provide for 'community' needs for the foreseeable future (school sites, recreation and municipal facilities, a valuable supply of earth materials such as sand and gravel, open space, trails, and natural resource protection) and provides an opportunity for tax positive commercial and industrial development that will create jobs and economic development.
Dam Feasibility Removal Study
The Souhegan River has been an integral part of Milford even prior to its incorporation in 1794. Over the years the citizens of Milford have utilized this waterway for fishing, pre-industrial power for mills, and a multitude of recreational activities including swimming and boating.
Osgood Pond Reclamation
Town staff continues to meet with the Army Corps of Engineers (ACOE) project team to determine the best methodology and associated cost for the Osgood Pond Reclamation project. Although discussed for many years and subject to federal funding delays and local concerns, the dredging of the Pond to reclaim it as a significant natural and recreational resource as identified in the Town's Master Plan remains a viable project. The ACOE has developed a methodology to pump dredged material from the Pond to the BROX property which will provide rich organic material for wetland restoration and tens of thousands of cubic yards of material to reclaim areas identified for future recreational fields. If the project is determined to be financially feasible, both the dredging of the Pond and the material for future fields will be of great benefit. Town voters, in support of the project over the past fifteen years, have set aside almost $100,000 in a special purpose fund towards the Town's 35% matching funds requirement for the project. Additional study is continuing to determine the full cost and financial feasibility of the project.
South Street Improvements
The long anticipated start of construction on South Street Improvements, funded by federal Transportation Enhancement and Special Purpose transportation funds and local matching funds continues to be a high priority. The project, which encompasses the stretch of South Street from Union Square southerly to the railroad right-of- way, includes widening a portion of South Street, undergrounding utilities from Union Square to the First Church of Christ Scientist, relocating overhead utility lines away from the curb from the Church to the railroad, and new sidewalks on both sides of the street, is complicated by complex utility design and easement negotiation.
Hotel Feasibility Study
For years the question has asked as to "Milford needs a hotel, why don't we have one?" This past February the Board of Selectmen, at the request of the Economic Development Advisory Council (EDAC) authorized EDAC to pursue the work necessary to determine the feasibility of recruiting a lodging facility to Town. A subcommittee of EDAC, working with this Office, has embraced the project, and with the generous donations of several local businesses has obtained matching funds to hire a respected consulting firm in the hospitality industry to prepare a preliminary feasibility study to determine if Milford has the market, demand, and location for a lodging facility. The subcommittee, in its due diligence talking with experienced developers, found that this type of preliminary study is an essential first step. The study was completed in August of 2011 and is available at the Office of Community Development.


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An aerial view of an extinct volcano covered with rain forest on Fergusson Island, Papua New Guinea. Illegal logging on Fergusson Island is rife, much of it is being committed by foreign companies.
© © Paul Hilton / Greenpeace
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