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|U.S. National Institutes of Health | www.cancer.gov
The Making of a Monoclonal Antibody
In cancer treatment today, three letters have infiltrated the oncology dialect: "mab," as in bevacizumab (Avastin), cetuximab (Erbitux), or trastuzumab (Herceptin). This suffix is reserved for monoclonal antibodies - agents that have become a growing component of the oncologist's arsenal.
Currently, eight monoclonal antibodies, or MAbs, are approved by the FDA to treat cancer. And many more are being tested in phase II and III clinical trials for a variety of tumor types.
To understand how these drugs work, one must take a careful look at the human immune system. The immune system comprises a diverse collection of specialized cell types that circulate through the bloodstream and lymphatic system, and monitors the body for bacterial, viral, fungal, and parasitic invaders. The "innate" immune response provides the first line of defense, and includes cells such as granulocytes, macrophages, and dendritic cells, which are always ready to recognize and attack foreign particles in the body. For persistent or recurrent infections, the sophisticated "adaptive" immune response comes into play.
Dendritic cells (DCs) form the bridge between the innate immune response and the antibodies of the adaptive immune response. When DCs digest a pathogen, they save and display foreign proteins found on the surface of the pathogen - known as antigens - for the lymphocytes of the adaptive immune system to recognize. When a B lymphocyte (also called a B cell) recognizes an antigen displayed by a DC as foreign, it changes into a plasma cell that secretes antibodies - small proteins that recognize and bind to the antigen, either interfering with the invader's ability to attack the cells of the body or marking them for destruction by other immune cells.
Cancer cells exhibit many of the behaviors of foreign pathogens, such as invading and damaging healthy tissue. However, explains Dr. Robert Kreitman of NCI's CCR, "In general, the immune system recognizes cancer cells as self and does not attack them as foreign antigens." This is because they carry many of the same surface proteins as normal cells, which mark them as part of the body. The development of MAbs circumvented this obstacle.
To create an MAb, researchers first identify a protein that is overexpressed on the surface of cancer cells and that the cells depend on to survive or grow. Trastuzumab, for example, is used to treat breast cancers that overexpress a protein called HER2, and rituximab (Rituxan) is used to treat blood cancers that overexpress the protein CD20. The more important the protein is to the cancer cell, the more effective the MAb will be as a therapy.
"Successful targeting of the HER2 protein has been the reason why Herceptin has been so effective," explains Dr. Charles Geyer, the National Surgical Adjuvant Breast and Bowel Project's director of Medical Affairs. "HER2 gene amplification and the resultant abnormal protein production clearly play a very important, central role in the aggressive malignant phenotype of HER2-positive breast cancers, and Herceptin appears to shut down the activity of the HER2 protein."
Once a target protein is isolated, it is injected into mice. Unlike the human immune system, the mouse immune system recognizes the protein as foreign and produces antibodies to fight it. These mouse antibodies are then isolated, but cannot be used directly as a therapy because they would be recognized as foreign and attacked as invaders if injected into the human body. So they must first go through a process called humanization.
In humanization, the variable domain of the mouse antibody - the very small portion that recognizes the human protein - is removed and grafted onto a human antibody. When introduced back into the human body, the MAb recognizes and binds to the target protein, disrupting a vital signaling pathway in the cancer cell.
Some MAbs are further engineered to carry a toxin or radionuclide, to increase the damage done after the MAb binds to a cancer cell, such as 131 I tositumomab (Bexxar), which is used to treat B-cell lymphoma. Because the MAbs bind predominantly to cancer cells, very few normal cells are damaged either by the antibodies or by their toxic conjugates.
Another class of therapeutic drugs called small - molecule inhibitors also target proteins on the surface of cancer cells. But MAbs are distinct from these agents because they also may play a role in activating an immune response called antibody-dependent cellular cytotoxicity. Researchers are now trying to better understand how MAbs interact with the rest of the immune system and how they can best be used with other treatments to maximize their effectiveness as an anticancer therapy.
"I think that discovering better combinations with other agents and the timing of how to give them to get the best response will be the future," says Dr. Kreitman. "In the 1950s and 1960s, we had chemotherapy drugs, but we didn't know how to combine them, so diseases like Hodgkin's disease were not curable. But as people learned how to combine drugs and do it safely… diseases started becoming curable. I think the same will happen with monoclonal antibodies and other agents."
By Sharon Reynolds


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And Now, an Insane Music Video About Knot Tying
What does the knot say?
What does the knot say?
The "bear-crow" comes armed with 25,000 volts of electricity.
Everyone's a critic, it seems—especially when it comes to national parks. Our man scoured Yelp to find out what some Americans really think about America's Best Idea.
Experts are pretty sure it's not a man in a bear suit.
A new interspecies alliance is born.
Yep, you read that right.
Rangers found the stash while investigating an illegally parked RV.
Because why not?
Or maybe it's just a big malamute...?
Local SAR personnel are not happy.
The bear plays the 'statue game' and wins.
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subset: commoncrawl


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Today Oasis sits on 9.5 acres on busy Avalon road; however we have only been here for a few years. From 2004 t0 2009 the congregation worshiped at the Oakland charter school. Prior to that the ministry was located on Hiawassee road in the Pine Hills area where it was started in 1960 by a few families who had migrated from the north. They desired to form a church so they began to gather and worship and then officially organized into a church.
While Oasis began as a mono cultural group mostly gathering northern transplants, it changed over the years into its present multicultural make up. Today Oasis serves many cultures and is inter generational. It is a place where families young and old can find a place along with youth, children and singles. There is a sense of caring and unity as well as the opportunity to experience very varied backgrounds.


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OMFSM! Doctor Who starts its new season soon and I could not possibly contain my fangirl excitement. Just…. SQUEEEEE! (I've been squeeing for a solid 10 minutes; I've scared my cats and my new roommate, I'm sure.) Anyway, watch this new trailer. Now. It's awesome :D
Edit: I just found this (slightly different) trailer that I hadn't seen before. Thought I'd share the additional awesomeness.


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I hate to do this, but two clarifications seem important at the outset: I adore Bob Dylan, and, as a lover of physical media, I'm one of the few people (twenty-somethings especially) still collecting CDs. With that said, I have to say this, too: there's no fucking way I'm plucking down $280 for the ... More >>
Perhaps you've read the weirdly fawning praise of Bob Dylan's tenth installment in his famed Bootleg Series, Another Self Portrait 1969--1971. ("One of the most important, coherent and fulfilling Bob Dylan albums ever released," some buffoon for Rolling Stone just claimed!) Perhaps, while in your ... More >>
"Lay Lady Lay" is a classic Bob Dylan tune, even if it doesn't sound like classic Dylan. 'Ole Bobby D. claims his voice sounded different on Nashville Skyline because he quit smoking before recording. Magnet and Gemma Hayes' soft, orchestral take on the song appeared on the Mr. & Mrs. Smith soundtra ... More >>
It's tough to hate kittens. It's even tougher to hate kittens that rock out to David Bowie. Just admit it: they're irresistable.Denying the cuteness of the cats isn't an option when those little critters are standing in on some major artists' album covers. This week we're bringing you The Ki ... More >>
You know the drill. Halloween wraps up, holidays come around, you step into a store and KAPOW. Whapped in the face and knocked about the ears by a whole mess of lousy sounds. You've just been assaulted by "Grandma Got Run Over By A Reindeer" for what you hope is (but you know isn't) the last time ... More >>
By this time you should be out of your turkey coma, foraging through your garage for that shabby box labeled: Christmas Lights. All that talk about department stores jumping the gun after Halloween is behind us, because it's time to show your Christmas cheer and light the night skies with those fam ... More >>
A scene from A Heroic LifeI didn't make it out to the French pop spectacular at FilmBar on Saturday night, but the pics posted on Facebook got me super-pumped to catch Serge Gainsbourg: A Heroic Life. Non-documentary or concert films are tough to pull off (those are, too) but when a movie ... More >>
To put it bluntly, I didn't know what to expect walking into Comerica Theatre last night.I'm a Bob Dylan fan, but let's face facts: He's 70. His most recent album, 2006's Modern Times and 2008's Together Through Life, have both been phenomenal efforts, but sounding good in the studio is ver ... More >>
William ClaxtonGood news for fans who are still miffed at Bob Dylan for canceling his appearance here in 2009: he's scheduled to play Comerica Theatre on July 18, and the stage is indoors and air-conditioned. Back in 2009, Mr. Dylan and co. canceled a stop at Camelback Park in Glendale due to fea ... More >>
Bob Dylan turns 70 today. The man who gave us "The Times They Are A-Changin'," the man who wrote "Like a Rolling Stone," "Mr. Tambourine Man," and "With God On Our Side." Over the years, he's influenced and remained busy. He inspired Sam Cook to write "A Change is Gonna Come," and even gave his ... More >>
Spider-Man: Turn Off the Dark director Julie Taymor has finally had enough of the Broadway show's complications and has chosen to step down from her position, according to Rolling Stone.For the time being, Taymor will still be the director and co-writer of the show, but she will no longer be pres ... More >>
President Obama said Bob Dylan was skeptical about a recent performance at the White House, according to NME.Dylan did not ask for a meet and greet with Obama, nor did he ask to take a picture with the President or even rehearse at the White House before his show. Artists who are invited to perfo ... More >>
The hits, they keep-a-comin'. Seattle's The Stranger recently conducted a brilliant field test, if you will, which forced four 17-18 year olds to listen to nothing but Bob Dylan for 3 days. Specifically, the youngsters had to listen to Dylan's exhaustive three disc set Biograph while they pa ... More >>
America's favorite old man/recording artist Bob Dylan tried to stick it to the man this past Wednesday night at San Francisco's Warfield Theater.The 69-year-old folk legend decided he was going to rebel against Ticketmaster and surplus ticket charges and nix issuing tickets to his show altogether ... More >>
Bob Dylan's fake? Them's fightin' words, Joni MitchellIn an interview with the LA Times, noted folk singer Joni Mitchell called out Bob Dylan, telling the interviewer she thought the celebrated musician was "not authentic at all."The two folk artists are no strangers, having spent plenty of ... More >>
Last night began the "In Performance at the White House" concert series, and focused on music from the civil rights era. Both Bob Dylan and Joan Baez performed, though not in fact together. (Initial buzz had specualted that they would be singing a duet.) Smokey Robinson, Yolanda Adams, the Blind ... More >>
"Oh brother" is more like it for passionate Bob Dylan fansLast Wednesday night, Nick Jonas went on Jimmy Kimmel Live to plug his brand-new album -- Nick Jonas and the Administration's Who I Am -- and shoot the shit with Kimmel. During the latter part of Jonas' segment, his recent role in the new ... More >>
Yes, that is Billy Bob Thornton's band. No, we didn't need to hear their latest album.Sometimes an actor feels necessary to spread out their talent to other venues outside of cinema. They remember playing guitar in high school and deem themselves worthy musicians, unleashing album after album of ... More >>
We get a lot of weird books and CDs in the mail, but the 600 page RightWing Bob: What The Liberal Media Doesn't Want You To Know about Bob Dylan is near the top of the list. The book, by Bob-obsessed blogger A.J. Weberman, makes the case.Weberman appears to be a certifiable loon: A self-proclaim ... More >>
Folk rock legend finally gives Phoenix a show
Bob Dylan's mystifying new Christmas music album is a confusing concept that makes for a disjointed, bizarre albumDo you hear what I hear? Yes, that is Bob Dylan singing "Little Drummer Boy." October 13 is finally upon us, and that means Christmas has come early for...Christmas music. Bob Dy ... More >>
Behold: the cover of Bob Dylan's new Christmas album. The times they are a-changin', indeedLet me preface this by saying that the fact Dylan is donating all of the U.S. royalties from his upcoming album to the charity Feeding America is a very noble move, and one that deserves respect. He obvious ... More >>
If you were one of the jilted music fans who got burned when Bob Dylan wimped out of his scheduled outdoor performance a couple weeks back, the folk rock legend has a way to make it up to you: He's putting on a free show...sorta. Dylan is set to perform at the Veterans Memorial Coliseum during ... More >>
Bob Dylan, ever the people's musician, has announced he will take on a summer tour of America's prestigious minor league baseball stadiums to Glendale's brand new Camelback Ranch Ballpark on August 11. He has also employed the services of über-American musicians John Cougar Mellenamp and Willie Nel ... More >>
Rolling Stone, that music magazine that felt it necessary to feature the ladies from MTV's The Hills on the cover of its May issue, just released its list of top 50 albums of 2008. Wouldn't you know it; they put Bob Dylan at number two. Why not number one, Rolling Stone? Maybe because they realize ... More >>
By P.J. Standlee Okay, maybe not everyone came to the Kokopelli Winery and Bistro's "Rock the Vine" 1970s festival Saturday night with their afro puffs puffed and their bell bottoms bottomed out, but late night bistro's atmosphere did provide a jam-happy Grateful Dead and Bob Dylan cover ba ... More >>
The changing face of Bob Dylan on film
The elusive Dylan, masterfully considered
The intimate pleasures and necessary detachments of Toronto 2007
The real deal
Your personal soundtrack = the perfect holiday gift
No Direction Home: The Soundtrack (The Bootleg Series Vol. 7)
Music From the Motion Picture Masked and Anonymous (Columbia)
Live 1975: The Rolling Thunder Review (Sony/Legacy)
The Last Waltz (WB/Rhino)
Latest music books struggle to demystify pop culture's greatest enigmas
Love and Theft (Columbian Records)
Bob Dylan's old enough to live in Sun City, let alone play there
Bob Dylan's career has only begun to recover from a slump that started 22 years ago in Tempe
The Bob-Man cometh; the Bash on Ash gets Hotter Than Hell; DJ Z-Trip bids farewell to the Valley
D.A. Pennebaker doesn't make history, but he's captured so much of it
Music critics reveal their deepest, darkest record-buying secrets in New Times' annual poll


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DeepField, the leading provider of Big Data solutions for Cloud Providers, Telecom and Cable Operators announced today five new large contracts for their Singularity™ Big Data platform and Cloud Intelligence™ application. The DeepField solution provides real-time analytics into cost, performance, and quality of experience across tens of millions of customers and terabytes of streaming data…Read More »
The Internet learned last night of a massive, wide-spread security vulnerability. Like something out of a bad Hollywood movie (see SwordFish), the default standard implementation of SSL was suddenly compromised. Badly. As in 30 lines of Python gives you remote private keys and passwords to tens of millions of sites. The Heartbleed vulnerability is simply…Read More »
Maybe it was love and millions enjoying a romantic night out. Or maybe it was a US electorate increasingly tired of politicians both real and fictional. Either way, Netflix's release of House of Cards last Friday failed to generate the same jump in both traffic and number of subscribers as season one. The below graph…Read More »
It gets you $8M if you are Bono and (RED). (update: red.org shows $2M as the donation maximum. iTunes shows $8M as the number. Either way, success!) One of the early commercials for Super Bowl XLVIII 2014 was of U2 performing 60 seconds of their new song Invisible. At the end was a message that…Read More »
DeepField, a leading provider of engineering and Network Analytics solutions for Carriers, CDNs and ISPs, announced today a multi-year, multi-million dollar contract from a major North American MSO for their largest instance of the DeepField Cloud Intelligence solution. DeepField Cloud Intelligence provides unprecedented visibility into Internet services and cloud infrastructure using next-generation big data analytics…Read More »
Last year we published a report showing just how big a deal Cyber Monday is for retailers. This year was no exception, new sales records being set not just for Cyber Monday but even on Thanksgiving. For this year we decided to do something slightly different than last year. We picked out a number of…Read More »
At 18:40 UTC Amazon Web Services reported performance issues for their North Virginia datacenter. The performance issues impacted services such as EC2, S3, SES, RDS, and Mechanical Turk among others. I decided to quickly pull some data together on what that looks like across a heterogeneous sample of North American Internet Service Providers. Below you…Read More »
A quick graph of Google's outage today. The below graph shows traffic to Google data centers across a diverse set of large North American providers. The outage impacting Google mail, search and drive services began at 6:45pm EST August 16 with services gradually returning to normal traffic volumes over the next hour. The graph does…Read More »
DEEPFIELD ANNOUNCES GENERAL AVAILABILITY OF ITS FLAGSHIP CLOUD ANALYTICS PRODUCT DeepField Cloud Intelligence Deployed Across 1/5 of US Internet ANN ARBOR, Mich., August 1, 2013 — DeepField announced today the general availability of its flagship Cloud Intelligence™ product. DeepField Cloud Intelligence provides real-time management of cloud and over-the-top services to dramatically improve performance and reduce…Read More »
Sometime over the last month, Google quietly broke an Internet record. Based on measurements of end device and user audience share, Google is now bigger than Facebook, Netflix and Twitter combined. An amazing 60% of all Internet end devices/users exchange traffic with Google servers during the course of an average day. This analysis includes computers…Read More »


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If you're upset about the E-Z Pass $.50 fee, you're not alone. Governor McAuliffe is joining in your battle. Drivers have been speaking out about the fee for more than a year. Now, the new Governor is helping shape a new proposal to do away with that fee altogether.
Drivers with E-Z Passes told us they buy transponders for the convenience. Instead of stopping at a toll, you can ride straight through. As it stands now - customers with them pay more than those who just use change. Some lawmaker says that was never the intent.
When in a rush, convenience makes travel easy.
"No stopping, no change. Before I had it, it was a real pain," one driver said.
Transponders help you get from point A to point B - eliminating the middle man of having to pay a person.
Delegate Manoli Loupassi says that was supposed to be an incentive.
"When they first came up with this if you had an E-Z Pass, you paid less than the people who paid tolls....so it's cheaper to have automation. So if it's cheaper to have automation, then why are you going to be charging me more than the people using the coins?" the lawmaker questioned.
He's referring to the 50 cent a month maintenance charge E-Z Pass customers began paying to VDOT in 2012. Now Governor McAuliffe is working with lawmakers to eliminate it.
"You already paid the $35. Really, it's not $35 if you're gonna add tax to it," said Charles Marks.
Thursday, VDOT officials said they are simply enforcing the state's law by charging this 50 cent fee, but the proposed new legislation would give VDOT until September to find a way to get rid of it.
Senate Bill 156 also calls for a better way of distributing transponders to customers. Right now, VDOT handles that. There are talks the DMV could get involved.
"Don't find 10 different ways to get me. Don't nickel and dime me, just charge me for the toll and I'll pay it," Loupassi added.
Some Virginia drivers admitted purchasing E-Z Passes from other states to bypass the monthly fee. Now, there are mixed emotions.
"50 cents. We can scrape that out of our pocket but if I don't see the results then I have a problem with the fee," Lashonda White said.
"For the convenience, the 50 cents a month was well worth it," another driver added.
Delegate Loupassi tried to pass similar legislation last year but it failed in committee. This new bill will be heard in a transportation committee Friday.
Loupassi is hoping with the Governor behind it this time, it could gain traction.
Copyright 2014 WWBT NBC12.
All rights reserved
An Arkansas State player tried to distract the opposition in an unusual way Saturday - by faking his death.
1909 Wynnton Road
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Object Recognition
Methods for object detection and recognition have been studied for several years. Here the focus of activities in particular lies on perspective based object recognition as well as on image and feature based registration methods.
Model based Object Recognition
A statistical approach to view based object modeling and recognition was presented in [Hornegger1994ORU]. In [Reinhold2001IA3 , Reinhold2001ASO] this work has been continued, whereas wavelets instead of point features were used. With these approaches, it is possible to identify and locate objects even before heterogeneous backgrounds. The object detection problem has thus been reduced to a statistical estimation problem. This work has also been continued in [Deinzer2005OAI]. With the help of a statistical eigenspace method it has been shown exemplarily, how a controllable camera can be used for a directed exploration, respectively for the view planning for object recognition. Furthermore basic research on current image-tracking procedures using structural geometry models has been pursuited. In parallel several approaches from the fields of Computergraphics and Image Processing have been investigated in these image-tracking procedures. In the work of [Ewering2006MTM] a prototype for model-based tracking with point and curve based features has been realized. For the point based approach Harris Corners have been detected and then described by an eigendescriptor. Eigendescriptors have the advantage that they can be compared effectively during the matching task. In the line based approach the wire-frame model of the tracking object has been back projected into the picture with the smallest possible error. Therefor the ideas from [Wuest2005ALT], where search-beams with a direction perpendicular to the edge-direction supply appropriate candidates for the line matching, were basically used. The approach had been expanded by additional line distance dimensions. These were able to contribute to a faster convergence of the pose determination. By combining these procedures the tracking became more stable, even when using very simple distance dimensions.
Today, model-based approaches normally use statistics, appearance, shape or
geometry, which mostly work without an explicit geometrical model schema [Cremers2006AMD, Seemann2006MDO].
We only use models where the modeling of the objects is in a explicit
form, like it is used in Computer Aided Design, which rather corresponds to the
human view [Wirtz2010MRO].
Using models for explicit knowledge representation, there are two main strate-
gies how a controlling algorithm can handle the analysis process (cf. [Niemann1990PAA] p. 240ff). On the one hand, there is the data-driven strategy, where segmentation objects, found in the image, serve as an initialization for the analysis. Based on the segmentation objects, the best possible model is sought. The model-driven strategy on the other hand works the other way round. Each model determines whether it is contained in the image or not and tries to locate its elements.
Hybrid forms are feasible and favored in most cases. We choose a hybrid approach where data-driven models become pre-evaluated and then we selectively search model-driven for segmentation objects [Wirtz2010MRO]. These strategies can be called task-independent because they do not refer to knowledge of the domain. Other systems exist which use ontologies such as OWL and combine them with uncertain knowledge for finding concepts in a domain [Hois2007TCO, Reineking2009ECO].
Color based Object Recognition
» see Color Image Processing
Ewering, Dag (2006): Modellbasiertes Tracking mittels Linien- und Punktkorrelationen. Universität Koblenz-Landau, Campus Koblenz, Fachbereich 4 Informatik, Institut für Computervisualistik.
Deinzer, Frank (2005): Optimale Ansichtenauswahl in der aktiven Objekterkennung. Berlin: Logos Verlag.
Wuest, Harald; Vial, Florent; Stricker, Didier (2005): Adaptive Line Tracking with Multiple Hypotheses for Augmented Reality.. In: Werner, Bob: ISMAR. IEEE Computer Society. S. 62-69.
Reinhold, Michael; Paulus, Dietrich; Niemann, Heinrich (2001): Appearance-Based Statistical Object Recognition by Heterogenous Background and Occlusions. In: Radig, Bernd; Florczyk, S.: Mustererkennung 2001. Heidelberg: Springer Verlag. S. 254-261.
Wirtz, Stefan; Häselich, Marcel; Paulus, Dietrich (2010): Model-Based Recognition of Domino Tiles using TGraphs. In: Pattern Recognition, Proceedings of the 32nd DAGM. Springer Berlin Heidelberg. Bd. 6376. S. 101-110.
Reinhold, Michael; Paulus, Dietrich; Niemann, Heinrich (2001): Improved Appearance-Based 3-D Object Recognition Using Wavelet Features. In: Ertl, Thomas; Girod, B.; Greiner, G.; Niemann, Heinrich: Vision Modeling and Visualization. IOS Verlag. S. 473-480.
Hornegger, Joachim; Niemann, Heinrich; Paulus, Dietrich; Schlottke, Gero (1994): Object Recognition using Hidden Markov Models. In: Gelsema, E. S.; Kanal, L. N.: Pattern Recognition in Practice IV: Multiple Paradigms, Comparative Studies and Hybrid Systems. Amsterdam: Elsevier. Bd. 16. S. 37-44.
Cremers, Daniel; Sochen, Nir; Schnörr, Christoph (2006): A Multiphase Dynamic Labeling Model for Variational Recognition-driven Image Segmentation. In: International Journal of Computer Vision. Bd. 66. Nr. 1. S. 67-81.
Seemann, Edgar; Leibe, Bastian; Schiele, Bernt (2006): Multi-Aspect Detection of Articulated Objects. In: onference on Computer Vision and Pattern Recognition - Volume 2 (CVPR'06). Bd. 2. S. 1582-1588.
Reineking, Thomas; Schult, Niclas; Hois, Joana (2009): Evidential Combination of Ontological and Statistical Information for Active Scene Classification.. In: KEOD.
Niemann, Heinrich (1990): Pattern Analysis and Understanding. Heidelberg: Springer Verlag. Bd. 4.
Hois, Johana (2007): Towards Combining Ontologies and Uncertain Knowledge. In: progic07: The Third Workshop on Combining Probability and Logic.


text:
SmartReloader® Mark XVI Single Stage Reloading Press
Item # WX2-205187
- Google+
This item is shipped directly from the factory. To see the expected shipping date, please add to your Shopping Cart. Sorry, no express shipping available. We are unable to ship factory direct items to Alaska, Hawaii, Puerto Rico or APO or FPO addresses.
- Details & Specs
Single stage SmartReloader® Mark XVI Reloading Press.
A heavy-duty steel casted Press for reloading any kind of ammunition, up to the 50BMG.
- Ambidextrous
- 1" ram diameter
- 2 primer arms: large and small
- Includes spent primer collection tube
- 7/8 "-14 thread on the installed bushing allows installation of all regular dies in the market
- Can reload up to 50BMG (1 1/4"-12 threaded dies) by removing the installed bushing
- Weighs 15 lbs.
- Reviews
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6 - Pk. Gun ClothsBuyer's Club $13.49 Non-Members $14.99
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text:
The best pack-and-go weekend bags
Play the field tote
The one thing that threatens your fun? A poor plan of attack. Check the weather, charge up your GPS and of course, pack the perfect bag. While everybody brings a few different things, we all share the need for the best roomy weekend bag possible. Before you start planning your excursions, be sure to pick one of these up. Travel well.
Bing: Play the field tote
The perfect size for a quick trip. Pack only the essentials, always play the field.
Weekend Tote, $248, Katespade.com
Everlane weekender bag
Everlane never fails to bring us solid basics at affordable prices. And we love the color.
Bing: Everlane bag
Weekend Bag, $95, Everlane.com
Coach Legacy leather tote
It's actually a man's bag, but who can resist that color?
Bing: Coach tote
Weekend Tote, $658, Coach.com
Clare Vivier weekend bag
Plenty of room for multiple outfits and it's the most beautiful green we've ever seen.
Bing: Clare Vivier bag
Weekend Bag, $483, Clare Vivier, BergdorfGoodman.com
3.1 Phillip Lim bag
Great for daily use, but when expanded it becomes the ideal getaway bag.
Bing: Phillip Lim 31-Hour bag
Weekend Bag, $750, 3.1 Phillip Lim, Barneys.com
Jack Spade nylon bag
Travel a lot? Go with a sturdy nylon bag, it will hold up longer.
Bing: Jack Spade nylon bag
Weekend Bag, $395, JackSpade.com
Acid wash denim bag
The lingering '80s child within us couldn't resist a little acid wash denim.
Bing: Acid wash denim bag
Weekend Bag, $49, BDG, UrbanOutfitters.com
Rail and Wharf weekend bag
A simple nautical take on the weekender—grab it for a boating excursion or the beach.
Bing: Rail and Wharf bag
Weekend Bag, $118, Rail and Wharf, JCrew.com
Upright duffle
If you're looking to make a statement, this collab between Eastpak and Central Saint Martins graduate Nicomede Talavera has your name all over it.
Bing: Upright duffle
Upright Duffle, $385, Eastpak x Nicomede Talavera, OpeningCeremony.us
WANT Les Essentiels De La Vie bag
Nobody ever went wrong with a trusty black bag. You'll have it for years.
Bing: WANT Les Essentiels De La Vie bag
Weekend Bag, $395, WANT Les Essentiels De La Vie, OpeningCeremony.us


text: A contemporary teens bedding collection in colors of indigo and white, the Steve Madden Skylar Indigo bedding ensemble lends a colorful and vividly sunny look to a variety of bedroom aesthetics including a dorm room, coastal, beach and nautical inspired themes. Available in Twin and Full-Queen sizes, the Steve Madden Skylar Indigo comforter set includes a comforter and standard sham (s). The comforter features dip dye artfully striped patterns in indigo and white on 100-percent microfiber. For adaptability, the comforter is reversible. Use the available decorative boudoir pillow embossed in di


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Next, you'll be asked to connect with Twitter. Rest assured, we will never send a tweet from your account
without your permission.
We will send you an email with an invite soon.
RT @Minus777: @Nigella_Lawson The English must regret saying "I'm so hungry I could eat a horse" now.
Grr. Need a winter timeshare in London. Snowy commuting from the wilds of Essex is always so frustrating!
RT @RuthieGledhill: Heading @Daybreak to talk about xPope and next Pope.
RT @yasminboland: Very curious info from @jonathanCainer about the Pope!
RT @janegarvey1: Pope's retirement home: Dunromeinn. Does that work? Been a long day...
RT @mrchrisaddison: I imagine Prince Charles is spending most of the day sending his mum email links to news stories about the Pope.
RT @Tigerlilywed: So new news :) alongside Love Scarlett we will also be launching Love Sebastian for grooms in spring 2013 more details to follow x
Follow @ruthieruth on Twitter


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Company Information
Company Profile
Find fast facts on PG&E. Serving customers from Eureka to Bakersfield. See our progress in your community.
Meet the officers of Pacific Gas and Electric Company.
PG&E Corporation
Visit the parent company of PG&E.
Diversity and Inclusion
Demonstrating our commitment to reflect the communities we serve.


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Readers blogs in Music
Sept. 15, 2014
| good morning Milwaukee!!!
Good morning Milwaukee! Milwaukee urban pop artist D-prostylez will be performing live on October 25th at 4:30 at the Wisconsin state fair park for the 4th annual latino family expo.
Posted by dprostylez at 10:35 a.m. | Talkbacks
Category: Music
July 8, 2014
| Cheap Trick Doesn't Disappoint
There are very few things in this crazy world and fast moving society that remain constant. Music styles change, star are made overnight and fade out even faster. Music has given way to the Johnny Bravo effect (as long as they fit the suit and look good the rest can be artificially pr...
Posted by WherestheMusic at 3:43 p.m. | Talkbacks
Category: Music
June 23, 2014
| Greetings from the Imposter: the Live Experience with Evil Twin and D'Amato at Stonefly Brewery
Greetings from the Imposter: the Live Experience and CD release party at Stonefly Brewery on 14 June was, in fact, an experience, and a memorable one at that, complete with party favors. The six-piece band filled the stage with energy and strong m...
Posted by kathy7 at 7:17 p.m. | Talkbacks
Category: Music
May 27, 2014
| Two Cow Garage show nearly ruined by shirtless fratboys
So this is what it has come to, the music I love and the bands I love having their shows hijacked by drunken, shirtless douche bag frat boys. Let me start from the beginning. I have been a TCG (Two Cow Garage) fan ever since seeing them play a show at the old Jim Heggertys about 11 years ago (i...
Posted by WherestheMusic at 3:30 p.m. | Talkbacks
Category: Music
April 28, 2014
| Ain't Kinda' Sorta' Misbehavin'
[image of William "Chick" Webb, 1930's from totaldrumsets.com]For whatever strange coincidence or intentional scheduling Milwaukee has so far this year played host to two --count 'em two!-- musical performances showcasing the brilliance of American composer and musician Thomas &qu...
Posted by eBot.s_beard at 5:36 p.m. | Talkbacks
Category: Music
Jan. 21, 2014
| nines LIVE - Brett Newski Solo - February 27, 2014
In an industry where the odds are stacked against the artist, Brett Newski is weathering the storm. From 2011-2014 he toured six continents, playing over 600 shows in America, South Africa, Australia, Asia, and Europe. Newski's hard-driving folk energy has been compared to t...
Posted by RiverClubMequon at 12:02 a.m. | Talkbacks
Category: Music
Jan. 20, 2014
| Valentines Day special performance by Vivo Jazz - February 14, 2014
Warren Wiegratz, Pam Duronio & Tim Stemper combined their creative passions to form a lively & contemporary jazz•pop bossa•samba music ensemble called VIVO. Although Warren is famed for his saxophone work, you'll also have the opportunity to experience his flute & m...
Posted by RiverClubMequon at 11:39 p.m. | Talkbacks
Category: Music
Jan. 19, 2014
| Kids from Wisconsin 2014 Auditions
Kids From Wisconsin is looking for ... well, more kids from Wisconsin.The popular summertime musical troupe currently has 33 open positions for dancers, vocalists and band members, male or female, between the ages of 15 and 20.The KIDS FROM WISCONSIN show troupe has been entertaining audiences al...
Posted by KidsfromWI at 5:51 p.m. | Talkbacks
Category: Music
| nines LIVE - Copper Box Duo - February 13, 2014
A spontaneous, combustible and genre-bending fusion of zydeco, blues, roots rock and even Tex-mex. Copper Box's sound connects the upbeat sounds of the upper Midwest with southern soul and fills it with groove and grit! Watch CBx bring in 2013 at nines --- http://www.yo...
Posted by RiverClubMequon at 4:16 p.m. | Talkbacks
Category: Music
| nines LIVE - Sawdust Symphony Band - February 6, 2014
Sawdust Symphony is an "American New Grass" string band, blending traditional bluegrass style with high energy contemporary musical forms. The members of the band are all from the Milwaukee, Wisconsin area. The group combines the members varying playing experience in bluegrass, old-...
Posted by RiverClubMequon at 4:07 p.m. | Talkbacks
Category: Music


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NEW YORK (AP) - Last winter took a toll on the Port Authority of New York and New Jersey's finances.
Overtime numbers were released for the first quarter on Wednesday, and the weather was blamed for pushing civilian overtime 200,000 hours over budget.
The Port Authority's director of management and budget says the budget was based on the last five winters. But last winter featured 22 snow events and dumped more than twice the average amount of snowfall on the area.
Most of the overtime was paid out at the tunnels and bridges, airports and the PATH rail system.
On the positive side, police overtime was 38,000 hours over budget, or about 14 percent. That's far lower than in recent quarters.
The Port Authority didn't provide dollar amounts for the overtime hours paid.
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Mission Statement
In the years to come, an open and collaborative relationship between the United States and China will be essential to global peace, security, balanced economic growth and environmental sustainability.
To help forge a more constructive bilateral relationship, Asia Society has established the Center on U.S.-China Relations with a generous gift from the late Arthur Ross.
In seeking new ways of building mutual understanding between the U.S. and China, the Center is undertaking projects and events which explore areas of common interest and divergent views between the two countries, focusing on policy, culture, business, media, economics, energy and the environment.
The Center, based at the Asia Society's New York City headquarters, has additional staff in the Washington, D.C. office, and works closely with other Asia Society Centers around the world.
Who We Are
Orville Schell is the Arthur Ross Director of the Center on U.S.-China Relations at Asia Society. He is a former professor and Dean at the University of California, Berkeley's Graduate School of Journalism.
Leah Thompson is the Assistant Director of the Center on U.S.-China Relations. She is the project director for COAL+ICE, and a multimedia producer whose recent work has been seen on ChinaFile, and translated for the Chinese edition of The New York Times. Originally from northern California, she holds a B.A. in history and American studies from the University of California, Berkeley and an M.A. in history from San Francisco State University.
Michael Zhao is a video producer for the Center on U.S.-China Relations covering China's environmental challenges. He is the creator of China Air Daily, ChinaFile's Environment Editor, and editor of China Green.
Laura Chang is a Senior Program Officer with the Center on U.S.-China Relations where she primarily focuses on policy and cultural programming. She is also Assistant Editor of ChinaFile and Editor of the Books section.
Multimedia producer David Barreda is the Visuals Editor for ChinaFile, a project of the Center on U.S.-China Relations. He was previously a staff photographer at the San Jose Mercury News, the Rocky Mountain News, and the Valley News.
Susan Jakes is the Editor of ChinaFile and a Senior Fellow at the Center on U.S.-China Relations. Previously, she worked for Time magazine.
Sara Segal-Williams is a Program Associate for the Center on U.S.-China Relations. She holds a B.A. from Bard College, where she concentrated in Chinese History, and an M.A. in International Relations from Central European University; she has also studied Mandarin Chinese at Qingdao University and Yunnan University.
Jonathan Landreth, ChinaFile's Managing Editor, is a reporter and editor who's been traveling to Asia since 1988. He has lived and worked in Singapore and China, often paying particular attention to the culture of the media and entertainment industries.
Ouyang Bin is an Arthur Ross Fellow at the Center on U.S.-China Relations at Asia Society in New York and Associate Editor of ChinaFile. Prior to joining Asia Society, Ouyang worked as a journalist in China and earned his M.A. from Harvard University. He was a Harvard-Yenching Fellow from 2010-2012.


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Australian Slang: A female bartender who takes her clothes off if she collects enough in tips. Common in the city of Kalgoorlie.
It's this diverse mix of customers who have all had a beer with a skimpy that makes the Kalgoorlie skimpy scene so unique, according to Wild West Saloon Bar manager and former skimpy Nicky who first came to Kalgoorlie to work five years ago during her university holidays. - The Kalgoorlie Miner
by mash92587 November 11, 2009


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La Quinta Inn College Station
607 Texas Ave
College Station, TX 77840
Phone: 1-979-696-7777
Fax: 1-979-696-0531
On Business Hwy. 6 (Texas Ave.), 1 block south of University Dr.
Detailed Map and Driving Directions:
Directions from Local Airport(s):
Easterwood Field
Start out going Northwest on West BYP by turning left. Then turn slight right onto University Ave.


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How many credited actors have played Michael Myers over the years? The first person to correctly answer will get a code redeemable for a free OnLive Play Pass for any game of their choice.
OnLive has achieved their goal of 45,000 likes on Facebook, so they're delivering on their promise. For the next 72 hours you can purchase a full PlayPass of Batman: Arkham Asylum for only 99 cents! Visit the link, and enter the promo code 99CENTS at checkout to receive the discount.
If you're not convinced how well OnLive works, give any of their regular PlayPass games a spin for 30 minutes free. Oh, and it's free to make an account as well. Also, feel free to take advantage of their 75% off Labour Day Weekend Sale, and the weekly $5 Friday specials!
Have you ever dreamt of being your own dictator? If you purchase Tropico 4 on OnLive by 09/07/11, you get a free copy of Tropico 3! Twice the south american dictatorship fun for one low price!
Things are still under construction around here. Due to the way we've decided to organize the site from now on, we're working out some hiccups with our domain and sub-domains, which I'm hoping will be resolved soon so we can start relaunching various parts of our network.
Also, we're gearing up…
Itching to get your hands on a copy of Deus Ex: Human Revolution? Moon Books has OnLive PlayPass codes to give away that can be redeemed for that, or any of the other great titles available on the service (excluding the monthly Play Bundle).
The site is currently down, but we're working hard on getting it back up and running, so in the meantime keep checking back here for details of how you can snag yourself a piece of the cloud gaming action.
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Spread the word about the Official Sixth Annual Auntie's Day, Sunday, July 27, 2014!We've designed these Posters and eCards just for you (and those who love you, Savvy Auntie!)Feel free to post these on your blogs, Facebook, Twitter, Instagram and Pinterest - anywhere you like!To share these, right click on the Poster or eCard you want to share and follow the directions to save or copy the image link. All we ask is that you don't modify the images without our permission, other than resizing. Facebook Profile Cover Image! Use these images to tell all your Facebook Friends that you're a Savvy Auntie! Use either one as your Facebook cover image! (The full image will show up when you save it.)Published for Auntie's Day, Sunday, July 27, 2014
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In response to AFNAV130's comment:
In response to carnie's comment:
In response to parhunter55's comment:
Sox now up 5 to 3 as Linares PH for Iglesias and has the RBI single. Marrero in at SS and Rubby rubs out Cards in bottom of the 8th. 3 up, 3 down.
I really like that guy. What does he need to do to get a shot at the big club?
Man I posted about RDLR a while back when NO ONE was talking about him. It's not hard just see what the Dodgers thought about him back in '11. Very, very high. They were saying he could be the best since they drafted Pedro. He gets traded and he's never mentioned in Sox off season plans. Now all the beat writers are saying he's awesome. Amazing etc etc. No kidding. I know. Tommy John. Well he was back with the Dodgers for an inninng before the trade deadline. He has 50 innings MLB experience. He's not a AAA pitcher. He's a 5 starter right now, or at the very least May/June. Start him in the pen for now. Funny he's this big revelation. Why no one lobbied for him or talked about him is beyond me. Lack of research is what that was.
It's actually kind of funny. A lot of the posters here were calling Rubby D and Webster farm scraps at the time of the trade, and claiming the trade was a straight salary dump. I said otherwise at the time but I was definitely in the minority. Of course I actually was talking about Linares in my post. :-)


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USDA home loan program helped widowed senior afford safe, year-round home in Breezy Point
Beverly Lawyer learned firsthand that there is much more to the U.S. Department of Agriculture (USDA) than meat inspection and production agriculture.
When her husband was alive, the couple took their RV to a warm locale during the winter and then lived in their three-season cabin in Breezy Point the rest of the year.
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Royals Press Releases
Tuesday, September 23, 2014
Tickets for potential tiebreaker game on sale Wednesday
Tickets Available Beginning at 10 a.m. at royals.com, by Phone & at Area Hy-Vee Stores.
Dates announced for 2015 Royals FanFest presented by Commerce Bank
The Kansas City Royals have announced that the 2015 Royals FanFest presented by Commerce Bank will take place Friday, January 30 and Saturday, January 31 at the Kansas City Convention Center's Bartle Hall.
Royals representatives contacting individuals with ticket purchase concerns
In regards to the issues with postseason ticket purchases yesterday, the Kansas City Royals have released the following statement: "Yesterday morning, the Kansas City Royals began the much anticipated ticket sales for potential 2014 MLB Postseason Wild Card and American League Division Series games at Kauffman Stadium.
Standing room tickets remain for Royals' three-game series with Detroit
The Kansas City Royals announced today that only standing room tickets remain for all three home games this weekend at Kauffman Stadium. The Royals face the Detroit Tigers tonight at 7:10 p.m., Saturday at 12:05 p.m. and Sunday at 1:10 p.m.
Gloves for Kids set for Thursday
The Kansas City Royals and broadcaster Ryan Lefebvre, with support from Royals Charities, Rally House, Pro Athlete, Inc. and 610 Sports, will host Gloves for Kids on Thursday, September 18. The annual event will be held at Kansas Sampler-Oak Park, located at 9750 Quivira Rd., in Lenexa, Kan., from 5-7 p.m.
Eric Hosmer Named Royals Nominee for the 2014 Roberto Clemente Award
Major League Baseball and Chevrolet, the official vehicle of MLB, announced that Eric Hosmer was named the Kansas City Royals 2014 nominee for the prestigious Roberto Clemente Award presented by Chevrolet.
Wild Card & ALDS tickets to go on sale to general public September 18
The Kansas City Royals have announced that tickets for potential Wild Card and American League Division Series games will go on sale to the general public on Thursday, September 18.
Shirts off their backs set for September 20
KANSAS CITY, MO (September 11, 2014) - As part of Fan Appreciation Day, Royals Charities will host Shirts Off Their Backs to benefit Ronald McDonald House Charities of Kansas City on Saturday, September 20 during the game against the Detroit Tigers. First pitch is set for 12:05 p.m.
Royals in the Community
To wrap up the home portion of the regular season, the Kansas City Royals will host the Boston Red Sox (September 11-14), Chicago White Sox (September 15-17) and Detroit Tigers (September 19-21) during a 10-game homestand.


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NEW YORK (AP) — A federal judge says people upset over the police crackdown on the Occupy Wall Street encampment in 2011 can't sue the company that owns the Manhattan plaza where the raid took place.
In a decision signed Thursday, U.S. District Judge Naomi Reice Buchwald said Zuccotti Park owner Brookfield Office Properties can't be held liable for any civil rights violations that occurred during the police action.
She said the NYPD, not the company, was making decisions about who to arrest and detain.
Police swept protesters and many bystanders out of the privately owned park two months into the occupation.
Some protesters, journalists and elected officials later sued, including a city councilman arrested as he tried to visit the scene.
The city and police officials remain as defendants in the suit.


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Gluten Freedom
The concept of the value and benefit of gluten-free food has been gaining momentum for the last 10 years. Today gluten-free diets are being adopted as an overall health-promoting measure by broad ...View Article
Crossroads Holistic Health Center is a full service natural health care facility which offers a wide range of natural health care services. We are here to guide and support your journey to health and abundant vitality. We specialize in both chiropractic and holistic care to provide the most effective combinations in natural health care.
Our mission: To help people thrive, not merely survive.
Experienced and attentive doctors, the founders, Drs. Chaz and Hollee' Rhinehart, (husband and wife team), share a common goal...to provide the highest quality natural health care possible.
Whether patients are seeking quick pain relief or natural healing and life long wellness care, Dr. Chaz and Dr. Hollee' focus on correcting the patterns of imbalance that are the underlying cause of health problems. As a result of this unique approach to health and healing, the patient's quality of life is improved.
At Crossroads Holistic Health Center you will receive the best of healing modalities through the use of modern chiropractic techniques, alternative medical analysis and therapies, laser therapy, flower essence remedies, homeopathy, emotional release techniques, aqua chi detoxification and nutritional supplementation, including vitamins, herbs and minerals. When necessary lab tests will be ordered to assist the doctors in the evaluation and care of each patient. Visit the technology tab on this site to view a list of lab tests conducted.
The doctors at Crossroads will provide a customized health rejuvenation program to fit your personal health care needs. All treatment programs involve addressing the "whole person" and incorporating healing on all levels of the person including the structural, chemical, emotional and energetic levels of the being.
The Crossroads doctors treat patients like you, who want to better themselves naturally. You will find that they have a genuine concern for your well-being and health.
If you are new to our website...welcome, and enjoy the path to discovering the wonders of chiropractic, nutrition, advanced laser technologies, alternative therapies and lifelong wellness care.
"The Doctor of the future will give no medicine but will interest his patients in the care of the human frame, in diet and in the cause and prevention of disease." ~Thomas Edison
Crossroads Holistic Health Center proudly serves patients from all over the United States while locally serving Southern California and our own hometown of Valley Center and our neighboring communities for 13 years.
Facebook site: Crossroads Holistic Health Center
"We May be More than Just an Answer...We may be the Only Answer."
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The concept of the value and benefit of gluten-free food has been gaining momentum for the last 10 years. Today gluten-free diets are being adopted as an overall health-promoting measure by broad ...View Article
In chess, checkmate occurs when a player's king is under attack and has no safe place to go. The king is threatened and every possible escape route is blocked. In life, a person may be similarl ...View Article
Cross-training refers to a combination of different methods of exercise. Specifically, cross-training refers to the combination of strength training and cardiovascular training in your overall exe ...View Article
Not too long ago, the Eighth Joint National released a new set of evidence-based guidelines for evaluation and treatment of hypertension (high blood pressure). The committee's report represents ...View Article
In general most people pay close attention to auto maintenance. Whether the concern is tires, brakes, or transmission, people make sure that their cars do what they need them to do. No one wants a ...View Article
Let's say you've been taking some time off from the gym. It's possible that one week turns into two or even three or four weeks. Life happens, and going to the gym starts to take a back seat ...View Article
A Thousand Thank You's could not express my gratitude; you have forever changed my life. I can now life a life full of energy, vitality, and purpose.
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Pa. ranks 3rd in nation for global warming from power plant pollution
Pennsylvania is the third most polluted state in the nation when it comes to global warming-causing emissions from power plants, according to a report released Tuesday by environmental advocacy organization PennEnvironment Research and Policy Center.
According to the study, titled "America's Dirtiest Power Plants," Pennsylvania's power plants are its single largest source of carbon pollution, responsible for 48 percent of statewide emissions and producing as much carbon each year as 24.9 million cars.
"America's dirtiest power plants are the elephant in the room when it comes to global warming," said PennEnvironment climate change and clean energy associate Elowyn Corby in a statement.
"If we want a cleaner, safer future for our kids, we can't afford to ignore power plants' overwhelming contribution to global warming."
Researchers said in a release that scientists predict the extreme weather events that have slammed Pennsylvania in recent years will only become more frequent and severe unless there are cuts to "the dangerous carbon pollution fueling the problem."
"We cannot afford any further delays in limiting the carbon pollution that increases the risk of floods, powerful storms and dangerous heat waves," campaign representative for the Johnstown area Sierra Club Tom Schuster said in a statement.
According to Dr. Robert Little, who practices family medicine at Pinnacle Health Family Care, unmitigated warming pollution leads to a host of public health risks.
"Rising carbon dioxide, CO2, contributes to global warming and it will cause more illness: asthma, infectious diseases and heat stroke," Little said in a statement.
Policy proposals
The report illustrating the scale of carbon pollution from Pennsylvania's power sector comes as the Obama administration prepares a new set of rules to tackle global warming.
President Obama this summer directed the Environmental Protection Agency to propose limits on carbon pollution from new and existing power plants, which are the largest single source of carbon pollution in the country.
The EPA is expected to propose an updated rule cutting carbon pollution from new power plants Sept. 29.
Pennsylvanians have already submitted more than 200,000 public comments in support of limiting carbon pollution from power plants.
"Coal-fired plants with technologies and equipment based in the 1940s do not belong in the 21st century energy portfolio of Pennsylvania," Lackawanna River Corridor Association executive director Bernie McGurl said in a statement.
"We support the work needed to reclaim the environments of Pennsylvania watersheds and communities from the legacy of the coal industry while we protect our land, air and water resources from potential problems associated with the gas production industry."
The PennEnvironment Research and Policy Center is calling on state leaders like U.S. Sens. Bob Casey and Pat Toomey to support limits on power plants' carbon pollution.
The organization is also advocating for state-level strategies to avoid climate change's worst impacts, such as increasing the share of renewable energy in Pennsylvania's portfolio and making the state a leader in green building standards.
"I don't think we want a summer climate in Pennsylvania similar to what Alabama has now, but that's what we can expect without emissions reductions," Professor Raymond Najjar of Pennsylvania State University's Department of Meteorology said in a statement.
"We've made changes before to clean our air and water, saving lives and money. It's time to do the same thing with global warming pollution."
Most odious offenders
The report noted, overall, the country's 50 dirtiest power plants – despite producing 30 percent of all power-sector carbon dioxide emissions – produced just 16 percent of the nation's electricity in 2011.
In fact, if the 50 most polluting U.S. power plants were an independent nation, they would be the seventh largest emitter of carbon dioxide in the world, according to the study.
Four Pennsylvania power plants ranked among the 50 most polluting in the nation, while seven power plants in the Keystone state were given the dubious honor of being on the list of the country's 100 most polluting power plants.
Pennsylvania's top five worst offenders in a ranking of national plants are:
8: FirstEnergy Bruce Mansfield in Shippingport
40: Hatfield's Ferry Power Station in Masontown
47: The Keystone Generating Station in Plumcreek Township
48: The Conemaugh Generating Station near New Florence
54: The Homer City Generating Station in Indiana County
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Scam Central
Store your belongings with confidence, not with fear of a scam
Better Business Bureau
June 28, 2012
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SAN ANTONIO, Texas -- Self-storage facilities dot the landscapes of new and older communities. Consumers rent units to empty overflowing garages, stash furnishings while moving or remodeling, or store business supplies for future use. Better Business Bureau recommends researching storage facilities prior to handing over precious belongings.
In 2011, BBB received more than 1,000 complaints against storage units. Many of the complaints came from consumers who were never able to access their storage units after paying a deposit. Others had their belongings damaged or stolen.
BBB recommends consumers take into account these seven factors before selecting a temporary storage facility:
1. Trust. Research any storage facility at
. Look at the business's BBB Business Review to check for any past history of complaints and how the company addressed those complaints.
2. Cost. Obtain written cost estimates from at least three facilities. Costs to consider include the monthly rental fee; storage preparation, padding, packing or transportation fees; and fees for extra options such as electricity, pest control and insurance.
3. Size. Consider the type of storage unit you will need to adequately store all your items. Ask if there are any restrictions on how you store your items within the storage unit. Some units may have a weight limit for contents stored within the unit.
4. Climate. Consider the general climate of the unit and whether your belongings will be subject to mold or water damage. If so, you may want to consider an environmentally controlled unit.
5. Insurance. Make sure your items are insured from theft, fire or other damage. The facility may provide basic insurance or you can choose to purchase insurance from an alternate source. Some homeowners' policies cover self-storage.
6. Safety. Ask if the facility has surveillance cameras on the property and if a system is in place to restrict access by non-renters. Ask for contact information to reach someone at the facility in case of an emergency, both during and after business hours.
7. Contract. Get everything in writing -- the size and location of the unit, options, termination regulations and insurance coverage. The payment terms and schedule should be clearly listed out as well. You do not want to accidentally miss a payment, have your storage unit labeled "abandoned" and then put up for auction.
To check the reliability of a company and find trustworthy businesses, visit bbb.org.
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Book your room at Villa Laetitia
Superior Double RoomMax Occupancy: 3 guests (up to 2 infants)
Deluxe Double RoomMax Occupancy: 3 guests (up to 2 infants)
Deluxe Triple RoomMax Occupancy: 4 guests (up to 2 infants)
Double Room Single UseMax Occupancy: 2 guests (up to 1 infant)
Standard Double RoomMax Occupancy: 3 guests (up to 2 infants)
Art Deco townhouse accommodation in Rome (Vatican - Prati) near National Gallery of Modern Art
This townhouse accommodation is located in Rome (Vatican - Prati), close to RAI Headquarters, National Gallery of Modern Art, and St. Peter's Basilica. Also nearby are Roman Forum and Villa Borghese.
Property Features
Villa Laetitia provides complimentary wireless Internet access, a rooftop terrace, limo/town car service, and dry cleaning/laundry services.
Room Amenities
In addition to premium satellite television, guestrooms include kitchenettes. Bathrooms feature bathtubs or showers and bidets.Information missing or incorrect? Tell us!
Villa Laetitia
At your hotel
A computer station is located on site and high-speed wireless Internet access is complimentary. Business-related amenities consist of limo/town car service and a meeting room. Event facilities measure 3228 square feet (300 square meters). For a surcharge, a roundtrip airport shuttle (available on request) is offered to guests. This Art Deco townhouse accommodation also offers a fitness center, a rooftop terrace, and tour/ticket assistance. A total renovation of this property was completed in 2011.
Villa Laetitia is a smoke-free property.
- Offsite parking discounted rates available
- Airport transportation (surcharge)
- Total number of rooms - 20
- Elevator/lift
- Fitness facilities
- Front desk (limited hours)
- Tours/ticket assistance
- Computer station
- Rooftop terrace
- Luggage storage
- Dry cleaning/laundry service
- Garden
- Number of floors - 2
- One meeting room
- Multilingual staff
- Room service (limited hours)
- Conference space size (feet) - 3228
- Conference space size (meters) - 300
- Number of buildings/towers - 1
- Wedding services
- Free Wi-Fi
- Limo or Town Car service available
- Year Built 2006
- Smoke-free property
Stay connected
Available in all rooms: Free Wi-Fi
Available in some public areas: Free Wi-Fi
Park your car
Offsite parking discounted rates available
In your room
- Connecting/adjoining rooms available
- Bathtub or shower
- Private bathroom
- Rollaway/extra beds available
- Premium TV channels
- Pay movies
- Premium bedding
- Balcony or patio
- Blackout drapes/curtains
- Air conditioning
- Kitchenette
- Complimentary bottled water
- Cookware, dishware, and utensils
- Refrigerator
- Minibar
- Daily housekeeping
- Bidet
- Bathrobes
- Complimentary toiletries
- Hair dryer
- Slippers
- Satellite TV service
- Individually decorated
- In-room safe
- Desk
- Climate control
- Frette Italian sheets
- Yard
- Espresso maker
- Free Wi-Fi
Eat and drink
Room service (during limited hours) is available.
The fine print for Villa Laetitia
When you arrive
Check-in time starts at 2 PM
Special check-in instructions:
When you leave
Check-out time is 11 AM
How you can pay
Accepted at this hotel: American Express, Carte Blanche, Diners Club, MasterCard, Visa
Your pets
Pets allowed, Only dogs and cats are allowed
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- A tax is imposed by the city: EUR 3 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.
- Self parking fee: EUR 20 per day
- Self parking fee for large vehicle: EUR 30 per day
We should mention
Cash transactions at this property cannot exceed EUR 999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation. This property offers transfers from the airport (surcharges may apply). Guests must contact the property with arrival details before travel, using the contact information on the booking confirmation. Children 3 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


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The 2012 Western Tech girls basketball team engraved its place in school history when the Wolverines became the first to win a regional championship.
Top-seeded Western Tech defeated visiting New Town, 42-36, Friday night in the Class 1A North Region final to earn the distinction.
The Western Tech boys lost to New Town on Saturday in their attempt to match the girls with their first regional title.
Western Tech's girls proved you can win even when the other team has the ball more often.
The Wolverines (22-4) overcame 44 turnovers, but forced 35 New Town turnovers. They also held them to just 23 percent (13-for-57) shooting from the floor.
Standout junior guard Jannah Tucker led New Town (20-6) with 23 points, but she had to earn them.
"Tucker is so good, so we said, 'you have to get a hand in her face and if she shoots jumpers all night we will be successful,'" Western Tech coach Nolan Roe said.
Junior forward Daija Coles (9 points) had the assignment of guarding her after being clear to play Wednesday after her tooth was knocked out in the county championship game against Milford Mill.
Tucker missed her first nine shots from the field in the first quarter, but hit a late free throw with 26 seconds for her only point.
At that time, the Wolverines led 13-5 and everywhere Tucker went, Coles and seniors Ateh Ade (8 points, 8 rebounds, 6 blocked shots and Jayde Duncan (8 points, 16 rebounds) shadowed her.
Western Tech sophomore Sydney Clopton was the Wolverines' offensive catalyst in the first quarter when she canned a pair of three-pointers.
"Sydney was great for us," Roe said.
Although she didn't hit another three pointer, she added four free throws and led the winners with 10 points and seven steals.
New Town trailed 23-15 at halftime and looked on the verge of getting blown out, with three starters saddled with three fouls each.
Western Tech went on a 6-0 run, capped by a banked trey from Coles with 6:56 left in the third period, that gave them a 29-15 lead.
That's when New Town's tenacious defense, that mirrors Western Tech's, took over.
Sparked by Tucker, Jasmine Cole, Keyaira Wilson, Amber Green and Tiana Davis, the Titans went on 12-0 run and closed the third quarter trailing only 29-27.
Tucker had nine points and Davis banked in the other three from long range.
"We had to stick together at that point," said Ade, one of three starting seniors with Duncan and Tyshay Montgomery. "If we didn't, we would have fallen apart."
Everybody stuck together in the final period with Montgomery and freshman Deja Dennis leading the way.


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'The Artist' earns best-picture Oscar; Streep, Dujardin win lead-acting prizes
LOS ANGELES (AP) -- Academy Awards voters have spoken up for "The Artist," the first silent film to triumph at Hollywood's highest honors since the original Oscar ceremony 83 years ago.
The black-and-white comic melodrama took four prizes Sunday, including best picture, actor for Jean Dujardin and director for Michel Hazanavicius. Not since the World War I saga "Wings" was named outstanding picture at the first Oscars in 1929 had a silent film earned the top prize.
The other top Oscars went to Meryl Streep as best actress for "The Iron Lady," Octavia Spencer as supporting actress for "The Help" and Christopher Plummer as supporting actor for "Beginners."
List of 84th annual Academy Award winners
List of the 84th Annual Academy Award winners announced Sunday:
1. Best Picture: "The Artist."
2. Actor: Jean Dujardin, "The Artist."
3. Actress: Meryl Streep, "The Iron Lady."
4. Supporting Actor: Christopher Plummer, "Beginners."
Suicide car bomber strikes at entrance to airport in eastern Afghanistan; 9 killed
KABUL, Afghanistan (AP) -- A suicide car bomber struck early Monday at the gates of Jalalabad airport in eastern Afghanistan, officials said, killing nine people in an attack insurgents said was revenge for U.S. troops burning Qurans.
The explosion comes after six days of deadly protests in Afghanistan over the disposal of Qurans and other Islamic texts in a burn pit last week at a U.S. military base north of the capital.
American officials have called the incident a mistake and issued a series of apologies. Afghan President Hamid Karzai has urged calm, saying that Afghans should not let the insurgents capitalize on their indignation to spark violence.
Monday's attack appeared to be a sign that the Taliban are seizing the opportunity to do just that.
The bomber drove up to the gates of the airport -- which serves both civilian and international military aircraft -- shortly after dawn and detonated his explosives in a "very strong" blast, said Nangarhar provincial police spokesman Hazrad Mohammad.
In Michigan, Santorum rejects Romney's claim of being a solid, consistent conservative
MARQUETTE, Mich. (AP) -- The question of whether Mitt Romney is conservative enough to deserve the Republican presidential nomination regained center stage in the GOP contest Sunday, with Rick Santorum saying the former Massachusetts governor fails the test.
Santorum urged Michigan voters to turn the race "on its ear" by rejecting Romney in Tuesday's primary in his native state, in which Romney is spending heavily to avoid an upset. Santorum said Romney's record is virtually identical to President Barack Obama's on some key issues, especially mandated health coverage, making him a weak potential nominee.
"Why would we give away the most salient issue in this election?" an impassioned Santorum asked more than 100 people in a remote, snow-covered region of Michigan's Upper Peninsula. Santorum, a former senator from Pennsylvania, said he is the true conservative on fiscal and social issues.
Romney rejected the claims.
"The biggest misconception would be that I'm a guy that comes from Massachusetts and therefore I can't be conservative," Romney told "Fox News Sunday." In his one term as Massachusetts governor, he said, he balanced budgets, reduced taxes, enforced immigration laws, "stood up for traditional marriage" and was "a pro-life governor."
Military identifies remains of the last American service member unaccounted for in Iraq
BAGHDAD (AP) -- The U.S military announced Sunday that it has recovered the remains of the last American service member who was unaccounted for in Iraq, an Army interpreter seized by gunmen after sneaking off base to visit his Iraqi wife in Baghdad during the height of the insurgency.
The remains of Staff Sgt. Ahmed al-Taie, who was 41 when militiamen seized him on Oct. 23, 2006, were positively identified at the military's mortuary in Dover, Del., the Army said in a statement released Sunday. Army officials said they had no further details about the circumstances surrounding his death or the discovery of his remains.
Al-Taie's brother, Hathal Al-Taie, told The Associated Press the military officer who visited the family's home to inform them about the remains said they are still in Dover, but that he didn't know the circumstances surrounding his brother's death.
"We have no information right now, not even how the body looks like or when they're going to release him," Hathal Al-Taie said by phone from Ann Arbor, Mich., where the family settled after leaving Iraq for the U.S. when his brother was still a teenager.
Their uncle, Entifadh Qanbar, said he was told by the Army major who informed the family in Ann Arbor that the remains were received at Dover on Feb. 22.
West dismisses Syrian referendum on constitution as 'farce' meant to justify bloody crackdown
DAMASCUS, Syria (AP) -- The U.S. and its allies dismissed the Syrian regime's referendum on a new constitution Sunday as a "farce" meant to justify the bloody crackdown on dissent.
But voters in government strongholds suggested why some Syrians have not joined the uprising against President Bashar Assad: Loyalty, distrust of the opposition and fear his fall will ignite a civil war.
U.S. Secretary of State Hillary Rodham Clinton called the poll "a cynical ploy" and urged Syrians who still support Assad to turn against him. A "farce" and a "sham vote" was how German Foreign Minister Guido Westerwelle described it.
"It's a phony referendum and it is going to be used by Assad to justify what he's doing to other Syrian citizens," Clinton said in an interview with CBS News in Rabat, Morocco.
"The longer you support the regime's campaign of violence against your brothers and sisters, the more it will stain your honor," she added, addressing Assad supporters, especially the military. "If you refuse, however, to prop up the regime or take part in attacks ... your countrymen and women will hail you as heroes."
Pressure builds to open US sky to civilian drone flights despite safety, privacy concerns
WASHINGTON (AP) -- Heads up: Drones are going mainstream. Civilian cousins of the unmanned military aircraft that have tracked and killed terrorists in the Middle East and Asia are in demand by police departments, border patrols, power companies, news organizations and others wanting a bird's-eye view that's too impractical or dangerous for conventional planes or helicopters to get.
Along with the enthusiasm, there are qualms.
Drones overhead could invade people's privacy. The government worries they could collide with passenger planes or come crashing down to the ground, concerns that have slowed more widespread adoption of the technology.
Despite that, pressure is building to give drones the same access as manned aircraft to the sky at home.
"It's going to be the next big revolution in aviation. It's coming," says Dan Elwell, the Aerospace Industries Association's vice president for civil aviation.
Democrats play defense on governors' races, but have hopes of winning Wisconsin recall
WASHINGTON (AP) -- Democrats are playing defense in governors' races in 2012, protecting eight seats -- some in conservative states like North Carolina and Montana -- while Republicans are safeguarding just four. But one of those is in Wisconsin, where a recall effort against incumbent Scott Walker has emerged as a national test of the confrontational measures many GOP governors have taken to balance state budgets.
Both parties agree the landscape is quite different than in 2010, where 37 states elected governors at the height of the economic downturn and amid roiling voter anger over government spending and debt. Republicans netted 6 new seats that year, including important presidential bellwether states like Pennsylvania, Michigan, Ohio and Wisconsin. There are currently 29 Republican governors, 20 Democrats and 1 independent.
This year, just 8 seats are up for grabs against a backdrop of a slowly improving national economy and a presidential contest that will draw a broader range of voters. Republicans are casting the contests as a referendum on their own party's leadership in tough times while Democrats are calling it a potential course correction after two years of GOP overreach.
"The public in a number of states in 2010 thought they were sending the message that with new leadership in the governor's office they'd get an accelerated recovery. Instead they got a hard right turn in ideology," said Maryland Gov. Martin O'Malley, chairman of the Democratic Governors Association in an interview.
O'Malley pointed to Ohio, where voters soundly rejected a ballot measure backed by Republican governor John Kasich to curtail public employee unions, and Florida, where Rick Scott's aggressive budget cuts and remote style helped sink his approval ratings to record lows last year.
Officials say 3 dead in derailment of Canadian passenger west of Toronto
BURLINGTON, Ontario (AP) -- A Canadian Via Rail passenger train derailed west of Toronto Sunday, killing three railroad employees and injuring dozens of passengers, officials said.
Via Rail spokeswoman Michelle Lamarche said the three people killed were all engineers riding in the cab of the locomotive at the front of the train when it derailed in Burlington, Ontario. A fourth Via worker in the locomotive was injured, she said.
Burlington Mayor Rick Goldring also confirmed that three people died in the accident.
Lamarche said no passengers died but 45 were injured. She said 75 people were on board the train traveling from Niagara Falls to Toronto when the train left the tracks around 3:30 p.m. Sunday within view of a residential area near Aldershot station.
The locomotive crashed on its side into a small trackside building, and at least two passengers car behind it were driven off the tracks into an L-shape. All six cars derailed, a Via official said.
Kobe Bryant, West hold on to win NBA All-Star game
ORLANDO, Fla. (AP) -- The Kevin and Kobe show won it for the West at the NBA All-Star game, holding off LeBron James at the end.
They got an MVP and a scoring record, too.
Bryant scored 27 points, moving past Michael Jordan as the career scoring leader in the game, Kevin Durant had 36 in an MVP performance, and the Western Conference held on for a 152-149 victory over the East on Sunday night.
James and the East cut a 21-point deficit to one in the closing seconds, but weren't able to move in front. James had 36 points and fellow Heat star Dwyane Wade finished with a triple-double.
"With all these great players on the floor, you never know what will happen. Guys making big shots and they cut it down to one. We were up 18 (at halftime)," Durant said.


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Tag: boondoggle
Winter Wake-Up app adjusts your alarms for bad weather
As we settle in for the rest of the long, cold winter, we're just about to hit the time of year where it's most likely you'll hear the two sweetest words in the English language. No, not "cellar door." I'm talking about "snow day." Winter Wake-up is a new app that combines two different usual...
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- Fantastical 2.1 for iOS adds new snooze, search and notification features


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Person DetailsUpdate
Mr. Tarkoff has been a director since September 2012. Mr. Tarkoff is currently President and CEO of Lithium Technologies and has been responsible for its strategic direction and corporate vision since September 2011.
From April 2008 to September 2011, he served as Senior Vice President and General Manager of Adobe Systems' Digital Enterprise Solutions business unit.
Prior to joining Adobe, Mr. Tarkoff held several executive positions at EMC Corporation, Documentum, Inc. and Commerce One. Earlier in his career, Mr. Tarkoff was an Associate Attorney at the law firm of Wilson Sonsini Goodrich & Rosati.
Additionally, Mr. Tarkoff is a member of the board of advisors for the Lawrence Hall of Science and has previously served on the board of directors for Borland Software Corporation and Onyx Software.
Mr. Tarkoff holds a J.D. from Harvard Law School and a B.A. degree from Amherest College.
Experience (2)Update
Lithium Technologies
President & CEO
Sep, 2011
Adobe Systems
SVP and GM of Digital Enterprise Solutions Business Unit, Sr. VP of Corp Development
2007 - Jan, 2011
Advisory Roles (1)Update
Advent Software
Board of Directors
2007 - Jan, 2011


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SCANDAL - "Snake in the Garden" - Abby and Harrison exchange suspicious glances while Olivia listens to what Hollis has to say.
Use a Facebook account to add a comment, subject to Facebook's Terms of Service and Privacy Policy. Your Facebook name, photo & other personal information you make public on Facebook will appear with your comment, and may be used on ABC's media platforms. Learn more.


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Generate revenue by housing federal prisoners
"Currently, the U.S. Marshal's office for the Northern District of Ohio spends millions of dollars a year to house and transport federal prisoners to correctional facilities outside Cuyahoga County. By increasing capacity in local jails through more efficient processing of criminal cases, these prisoners could remain in Cuyahoga County's detention facilities. This simultaneously saves money in transportation costs for the U.S. Marshal's office while providing a consistent revenue stream for local law enforcement agencies."
Ed FitzGerald, "Law Enforcement Strategies for Safer Neighborhoods" campaign policy statement
Ed FitzGerald, "Law Enforcement Strategies for Safer Neighborhoods" campaign policy statement
Subjects: County Budget, Criminal Justice
We want to hear your suggestions and comments. Email the Truth-O-Meter with feedback and with claims you'd like to see checked. If you send us a comment, we'll assume you don't mind us publishing it unless you tell us otherwise.


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Post: Randall's Parking Pass!!
~ This transaction was just like you said...Quick, easy and painless. You were a pleasure to deal with! this was my very first transaction on cash or trade...and it was lovely :)Thank you so and Enjoy the show too!!!7/10/14
Post: FT - My Single Ticket 12/30 For Your Single Ticket 12/28
~ Great trade! Everything was arranged a few weeks ahead of time, and the trade went smoothly. Thanks!1/18/13
Post: TRADE FOR CUPUSCAKUS ONLY
~ Good fan, good trader, and a quick payment. Enjoy the show.12/10/12
Post: FS: 1 Extra Trey Anastasio Beacon NYC 10/26
~ Immediate payment & great communication! Fantastic contributor to the cashortrade community.10/17/12
Post: Can You Help Me GMMFDS At Dicks?
~ Great buyer! Stuck to your word and made instant payment! Thank u! May u rage da tour with your phriends! :D8/16/12
Post: ISO: 1 Bethel Pav Sunday
~ Thanks5/23/11
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Duluth, MN (KDAL) - The two victims of a Saturday night shooting in Grand Rapids remain in critical condition here in a Duluth hospital. Fifty nine year old Rosemary Johnson and her thirty-two year old son Paul Johnson were allegedly shot in their Grand Rapids home on Saturday by jealous husband William Payne. The twenty six year old Bovey man is in custody charged with eight felonies.
No suspect in the stabbing death of a Duluth man in his Central Hillside apartment last Friday night and in Wauwatosa, Wisconsin authorities arrested the husband of a police officer who was shot and killed Christmas Eve.


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Siblings Brandy and Ray J stopped by the Lopez Tonight Show this week to promote their VH1 show 'Family Business', which kicks off this coming Sunday (April 11th).
The pair chatted it up with host, George Lopez, about a number of topics – including Brandy's rumored relationship with Flo'Rida, Ray J's infamous 'tape', their brother-sister dynamic, of course the show, and much more.
But Brandy's reaction when Kim Kardashian's name comes up is…priceless!
GALLERY: Brandy & Flo-Rida Get "Friendly" In Miami
SNEAK PEEK: Brandy & Ray J's "Family Business" Episode
OUCH! Ray-J Calls Kim K "That Other Girl" On-Air
Brandy and Ray J
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Fifth Third Bank's 28th annual Brighten A Child's Life campaign to benefit Children's Miracle Network Hospitals, officially began Wednesday with a tree-lighting ceremony in the Fifth Third Banking Center downtown. The fundraising campaign will continue through Dec. 31.
Participating in the tree-lighting ceremony was Lucy Serna, a 5-year-old patient at Mercy Children's Hospital that was born with Atrial Septal Disorder. President and CEO of Fifth Third Bank Bob LaClair; Carla Nowak, vice president of marketing; and Donna Ruedisueli, director of Women's and Children's Services at Mercy Children's Hospital also participated in the ceremony.
Throughout the campaign, holiday trees will be located at the 47 Fifth Third Banking Centers and Bank Mart locations in northwest Ohio and southeast Michigan. Each person who makes a donation will have the opportunity to add his or her name to the Brighten a Child's Life light bulb ornament.
Proceeds from the event will benefit pediatric services at Mercy Children's Hospital. Some of the services include, the Autism Clinic, HippoTherapy services, Child Life program and Family Care Team.
"Fifth Third Bank has an outstanding tradition of support, and Mercy Children's Hospital is so grateful for the generosity of this community leader. This campaign supports a variety of programs, helping to ensure our patients receive the best possible pediatric care," said Barb Martin, chief administrative office of Mercy Children's Hospital.
This year's campaign will add to the $841,791 that has been donated over the past 27 years.
Copyright 2013 Toledo News Now. All rights reserved.
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Luann Lafreniere
Luann Lafreniere has lived in the Jaffrey NH area most of her life. Her professional career began when she ran and owned a plastic molding sales representative business for several years. After selling the business, she worked as a real estate agent but soon realized that manufacturing was where her heart belonged.
She then joined New England Wood Pellet in 2003; and since then, Luann has held many positions and has helped the company grow to become an industry leader. Her most significant roles were as the Project Managers for the construction of our state-of-the-art pellet manufacturing facilities in Schuyler and Deposit, NY.
She currently serves as the company's first Quality Manager, and has overseen the development and implementation of the company's ISO-based Quality Management System. Luann was instrumental in guiding the company to become the first company to be certified under the Pellet Fuels Standards Program, a third-party accreditation program providing specifications for residential and commercial-grade fuel.


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Colorado embraces an "All-Hazards" planning approach to emergency management. To enhance planning and coordination efforts, Colorado is divided into nine All-Hazards Regions.
Various agencies, including Homeland Security, emergency management, and public health, work within these regional boundaries to facilitate local prioritization, teamwork and collaboration among neighboring counties and tribal governments. This approach fosters resource sharing and builds sustainable capabilities and early consensus among stakeholders.
All nine regions of the state are provided with regional public health emergency preparedness and response staff, which includes at least one regional planner, regional epidemiologist and regional training coordinator to assist in the planning and coordination of public health preparedness activities. All regional staff positions are housed at, and employed by, local public health agencies throughout the state.
Regional staff provide support to local health departments and nursing services as well as to regional and local emergency preparedness partners. Their efforts ensure that public health response is integrated into county and regional emergency response planning efforts.