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Odds and Sods
They put Sheldon Souray back on the DL today, his body unable to endure the pounding of a long season. He'll probably be back at some point but we should probably brace ourselves for the "we're shutting him down so he'll be ready for next year" press release. Souray seems like a decent fellow and his shot from the point looked dangerous when we saw it but the bet seemed risky and the pricetag too dear and the result is no different now that the cards have been dealt.
According to Hoyle, the Oilers need to do some price shaving similar to WAL-MART in order to get some wiggle room by summer. Word today than an NHL General Manager told The Hockey News that he expected someone would be willing to make a nice offer to Kevin Lowe for defender Steve Staios. The writer is a fellow named Adam Proteau and to quote the article "as one Western Conference GM (who spoke on condition of anonymity) told thehockeynews.com Tuesday, Edmonton blueliner Steve Staios might be an attractive alternative to a team that loses out on the upcoming Brian Campbell trade deadline sweepstakes. I really think (Lowe) will get an offer for him – and under the right circumstances, it might even come from me."
My guess is that it's Doug Wilson from San Jose.
Sending away Staios probably gives the Oilers more money to spend on Joni Pitkanen and that would have to be considered a good trade at this point in time. The Oilers should keep both of them, mix in Gilbert, Souray, Smid and Greene for the fall and add another veteran to that group but the reality is that the contracts of Souray, Pitkanen and Gilbert will take up so much money they'll be rolling those three plus a trio of kids again next season.
And that is best case scenario. Worst case is they deal Pitkanen for something less than immediate help and get shutout in the summer when trying to pluck a useful veteran from the UFA tree.
Shawn Horcoff also has a problem shoulder and he apparently tweaked it at the All-Star game. The Oilers need their best veteran players and losing him for any length of time would make this team all but unwatchable. Having said that, it might give one of the minor leaguers a chance to step into the lineup and get some playing time.
The Oilers at this point in the season have devoted so many at-bats to young players it seems incredible that their depth chart at center could soon be Stoll-Gagner-Cogliano-Schremp but we're not far from it as we speak.
When do pitchers and catchers report anyway? Did Jesse Orosco catch on with anyone? What about Jeff Fassaro?


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LOUISVILLE, Ky. (WHAS11) -- Louisville Mayor Greg Fischer has a challenge for Louisville residents to step up and help the city break its own record for public service.
"One of our goals since day one is to take what we have in this city already, which is great hospitality and caring, and ignite a brushfire of compassion that makes Louisville one of the most caring and compassionate cities in the world. And I think we're well on our way," Mayor Greg Fischer said.
The second "Give A Day" volunteer week is April 13 through 21 and residents are being urged to volunteer their time, give blood, and donate a canned good or even just help a neighbor.
Last year's week produced more than 90,000 volunteers and acts of compassion; the goal this year is $100,000.
On Wednesday, April 3, WHAS11 will take part in the mayor's challenge. We're having our own "Give A Day" telethon during our newscasts from 5 to 7 p.m. It'll be your chance to call in to volunteer your time.

subset: commoncrawl


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Dimension, depth and sophistication come together perfectly in this Lush Decor shower curtain.
- 72" x 72"
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Attention: shower curtain liner recommended.
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Terrific Kid Gift Certificate Winner
Pictured with Bladenboro Primary School principal Deborah Guyton is Natalie Britt, kindergartner who was the winner of a twenty-five dollar gift certificate to Pizza Palace of Bladenboro. First Citizens Bank of Bladenboro donates twenty-five dollars for the purchase of the Pizza Palace gift certificate to the winner of the monthly drawing at each of the Terrific Kid ceremonies for the school year.
Bladenboro Primary School Terrific Kids
Pictured are the recent recipients of the Terrific Kid award at Bladenboro Primary School. Each month the students who are chosen Terrific Kids are recognized at a ceremony where they receive a Terrific Kids certificate, bumper sticker, and pencil. Pictured with the students is John Howard Ward of the Kiwanis Club of Columbus County. The club sponsors the Terrific Kid program at Bladenboro Primary School.
Copyright © 2014 Bladenboro Primary School


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I travel, I write, I take photos. And I'm constantly relived the Internet has 0 calories.
South African by birth. Canadian at heart. And currently living in Toronto, Canada. I believe in daring to live the life you dreamt of, which means I quit my cushy, high finance job in Toronto to travel the world and see where life took me. Cheese has always held a special place in my heart, fine! and on my hips, which meant running my four full marathons was quite the big feat. I've also hiked to Base Camp Mt. Everest, and explored the vibrant culture, temples and beaches of Southeast Asia. Bungee jumped in New Zealand was still my biggest leap of faith, but I've been lucky enough to counteract that with whale watching in Perth, and spending summer days in Australia's stunning Whitsunday Islands.
I love overly priced high heels, bright nail polish, and lush green grass. New socks, bright running tops and wool sweaters also hold a special place in my heart. I'm a dog and horse person, Rhodesian ridgebacks and American Saddlebreds are my breed of choice.
Today you can find me back in a routine in Toronto's mid-town working for a company I adore as a Community Project Manager. I've settled into a little apartment by myself, as I get ready for the next chapter in my life.
Oh. Oh hello there you ridiculously, ridiculously good looking person (flatter them? Check). Thank you for stopping by. So…
Where to start? Should I tell you the basics first? Yes. Let's go with that. My name is Liz *waves frantically to you* and I'm a 29-year-old Canadian, female in a perpetual state of trying to lose weight.
Yea… so there's that; "trying to lose weight" has officially become part of my basic statistics, but hushhhhh. Because before you go get all up in my grill about that being so "sad" and "depressing," hear me out…
Actually, first you need to know that "One Twenty Five," my blog's name, is actually my goal weight in pounds (f, small framed, 5'4" – Look it up - it's true), and yea… somehow, someway I woke up after over five years of blogging (whoa) and still do not weigh One Twenty Five. (Read from the beginning!)
So yea… I have to admit I somewhat feel like a huge failure because I've never got close to my goal weight (my lowest was 147 pounds, bikini proof here!), but on the other hand I am also quite pleased with my life… and that, my new friends, is a wonderful thing for me to say.
Why? Because it's taken me a long, long time to realize that wanting to lose weight & being unhappy with your body does not mean you hate yourself. BAMN! On the contrary, really. It means I want what's best for me-me-me, and losing weight, getting healthier, and let's be honest, sexier, is what's best for me.
But it's a fine balance, isn't it? Wanting to lose weight, and then actually losing weight, yet still getting on with your life and living? And I suppose that, in a nutshell, is what my blog, this blog, is about.
I used to sit at home and dwell on wanting to be skinnier, wanting to be thinner, smaller, prettier, (it was an obsession for me) in order to live my life. In order to go, see, and do. But that was rather stupid of me, wasn't it? So now, five years later, and after LOTS of lessons learned, I am out (finally) living and being present in my every day, while still continuing on my voyage (yes, voyage) to shed the lard.
Although, because I am too honest for my own good, I need to tell you a secret: when I was 26 I lost 50 pounds (high five! And athankyouverymuch as that was damn hard work), and life became better from not being that fat. There. I said it. So yea, because I know & truly believe this, I do think losing weight (or really, being healthy) is really, REALLY, important to *my* life.
So the key, in my mind, is to have losing weight/being healthy as a good, proper slice of the pie chart that is my life. It shouldn't, like in my early twenties, be the entire damn chart. Make sense? I hope so.
ANYWHO, so in 2011, after gaining the confidence from my 50 pound loss, I quit my corporate job in downtown Toronto, said goodbye to my friends, high heels, & beautiful apartment and headed into the great, big world (Berlin, Croatia, Nepal, Vietnam, Cambodia, Thailand, Malaysia, Indonesia, NYC and Boston – lots more on travel info found here!), and then closed my eyes and moved to Australia for a year and a half. I KNOW, right? Whoa.
But-but-but. Unfortunately, despite seeing & doing & living I also ate-ate-ate the world on my way to Australia (and then while I lived there), and suddenly found my weight up, and my clothes not fitting. Booooooo! But luckily, this time? This time I was, wait, am, older and wiser and not as stupid as I was when I was younger which means I can wholeheartedly say I am living my life everyday to its fullest, despite carrying extra weight for moi! And? And it's pretty damn great..
I've hiked to Base Camp Mt. Everest in Nepal, run three full marathons (Chicago, Las Vegas and Berlin) and this October 2013 plan on running my fourth – Chicago (again) to raise money for Multiple Scoliosis Canada. It's exciting! I am also a CrossFitter, and Paleo (wannabe) eater, but you can read lots more about those topics by clicking on the links.
I'm also (after twenty one months away) moving back to Toronto, Canada in May 2013 and will be starting my life from scratch. So umm, yea… that's terrifying. I'm going to be a busy-bee trying to find a new job, new place to live, new Crossfit, running group and, well, pretty much a life. So yup, there's that.
I am also somewhat addicted to horse riding, kayaking in the Toronto harbour, dressing up with my friends, and admiring high heels I can't afford – so life in the coming months is sure to be hectic!
Oh! And, I suppose I should mention I'm incredibly honest on my blog (125 *very honest* facts about me!), I've struggled with Binge Eating and throwing up, and pretty much tried every diet on this Earth (proof!), but learned in the process there is no secret code, no magic potion, no special sword to slay the dragon that is being over weight; it's hard work, takes a long time, and can only be done from a series of millions of moments of motivation.
So yup. There's that. Me in a nutshell. So please follow along as I reach for the stars, fall on my ass (a lot), try and avoid chub-rub, lose a few (or 50) pounds, and tick off some life goals on the good, old bucket list, one day at a time.
Welcome! I'm Liz, and I'm so pleased you're here!
Coming Soon!


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15 U.S. Code § 68d - Enforcement of subchapter
(a) Authority of Commission
Except as otherwise specifically provided herein, this subchapter shall be enforced by the Federal Trade Commission under rules, regulations, and procedure provided for in the Federal Trade Commission Act.
The Commission is authorized and directed to prevent any person from violating the provisions of this subchapter in the same manner, by the same means, and with the same jurisdiction, powers, and duties as though all applicable terms and provisions of the Federal Trade Commission Act were incorporated into and made a part of this subchapter; and any such person violating the provisions of this subchapter shall be subject to the penalties and entitled to the privileges and immunities provided in said Federal Trade Commission Act in the same manner, by the same means, and with the same jurisdiction, powers, and duties as though the applicable terms and provisions of the Federal Trade Commission Act were incorporated into and made a part of this subchapter.
The Commission is authorized and directed to make rules and regulations for the manner and form of disclosing information required by this subchapter, and for segregation of such information for different portions of a wool product as may be necessary to avoid deception or confusion, and to make such further rules and regulations under and in pursuance of the terms of this subchapter as may be necessary and proper for administration and enforcement.
The Commission is also authorized to cause inspections, analyses, tests, and examinations to be made of any wool products subject to this subchapter; and to cooperate with any department or agency of the Government, with any State, Territory, or possession, or with the District of Columbia; or with any department, agency, or political subdivision thereof; or with any person.
(b) Maintenance of records by wool manufacturers
Every manufacturer of wool products shall maintain proper records showing the fiber content as required by this subchapter of all wool products made by him, and shall preserve such records for at least three years.
The neglect or refusal to maintain and so preserve such records is unlawful, and any such manufacturer who neglects or refuses to maintain and so preserve such records shall forfeit to the United States the sum of $100 for each day of such failure, which shall accrue to the United States and be recoverable in a civil action.
Source(Oct. 14, 1940, ch. 871, § 6,54 Stat. 1131.)
Transfer of Functions
For transfer of functions of Federal Trade Commission, with certain exceptions, to Chairman of such Commission, see Reorg. Plan No. 8 of 1950, § 1, eff. May 24, 1950, 15 F.R. 3175, 64 Stat. 1264, set out under section 41 of this title.
The table below lists the classification updates, since Jan. 3, 2012, for this section. Updates to a broader range of sections may be found at the update page for containing chapter, title, etc.
The most recent Classification Table update that we have noticed was Tuesday, August 13, 2013
An empty table indicates that we see no relevant changes listed in the classification tables. If you suspect that our system may be missing something, please double-check with the Office of the Law Revision Counsel.
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LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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The 2014 AAUP Book, Jacket, and Journal Show features the latest in excellent scholarly book design, and premiered this summer at the AAUP Annual Meeting. Starting in September, the 2014 show will begin traveling to presses around the country. First stops: New York, New Jersey, and Ohio!
The AAUP Residency is a unique professional exchange that allows staff from member presses to spend up to a week learning new skills and best practices at another press. Eight applicants were selected to complete residencies in 2014.
The 24th edition of our librarian-vetted bibliography of university press and scholarly titles is now available. The "Best of the Best" were presented at ALA 2014 in Las Vegas.
Formally established in 1937, AAUP promotes the work and influence of university presses, provides cooperative marketing opportunities, and helps its 130+ member presses fulfill their common commitments to scholarship, the academy, and society. AAUP members are active across many scholarly disciplines, including the humanities, the arts, and sciences, and are innovators in the world of electronic publishing.
Knowledge, Not Just Information
Higher Education
> Go to book list
Recommended Reading: 2014 Digital Book Publishing Survey
Recommended Reading: "University Presses Under Fire" by Scott Sherman (The Nation)
Recommended Reading: The Digital Digest an AAUP blog
AAUP offers a wealth of resources for members and our broader community.


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Sample seafood in Lima, marvel at the Sacred Valley, conquer the Inca Trail to Machu Picchu.
Like our 'Inca Discovery' tour but with a flight back to Lima, this trip offers a fascinating combination of the region's archaeological and cultural treasures. Retrace the steps of the Inca on a four-day trek along the Inca Trail to Machu Picchu. One of the world's best-known hikes, it will reward those willing to break a sweat with stunning views of ruins and cloud forests. We run our own treks, which ensures fair treatment of our porters and quality equipment. Our expert CEOs will make certain the first glimpse of Machu Picchu from the Sun Gate will burn itself into your memory.
Ready to hit the Inca Trail? Get familiar before you go.Learn more
Arrive at any time.
Free day for shopping and exploring the city. Optional city tour.
Full-day guided tour of the Sacred Valley and Ollantaytambo ruins along with a visit to a Planeterra-supported women's weaving project in a local community. Visit the Planeterra-supported Sacred Valley Community Restaurant in Huchuy Qosco, an indigenous village for lunch. Shopping opportunities at a local market.
4-day guided Inca Trail hike with visit to Machu Picchu. Enjoy Planeterra-supported handmade biodegradable soap products for use on the Inca Trail. Optional visit to the Inca Bridge before returning to Cusco.
Fly back to Lima.
Depart at any time.
Find dates, prices, and more trip options.Book Now


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SHERIDAN—There will be a free Caregiver Conference at the Holiday Inn Oct. 3 and 4. All caregivers all welcome and the conference will feature general information and focused sessions on Alzheimer's Disease. Register by Sept. 30 by calling 1-877-926-8300 and ask for the Sheridan Caregiver Conference. Or go online at www.uwyo.edu/wycoa. Events will kick off Friday with an appreciation dinner and will wrap-up Saturday around 5 p.m. The Holiday Inn is located at 1809 Sugarland Dr.
SHERIDAN—The Sagebrush Community Art Center is having kids' Halloween costume classes Saturday, Oct. 4 and Saturday, Oct. 11.
On Oct. 4, the kids will be making masks and on Oct. 11 they will be designing their own costumes. There is a $6 registration for each class.
You can make reservations by calling 674-1970 or enroll on the same day of the class. For more information, call Sagebrush Community Art Center at 674-1970.


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Submissions are being accepted through Monday, February 11th for WALL Literary Journal, which has won first place in a national competition for college literary magazines sponsored by the American Scholastic Press Association. Now in its 13th year, WALL annually publishes short stories, poetry, personal essays, art, and photography by Saddleback College students.
For further information, please see the WALL website at /la/Wall.html or contact Gina Shaffer at email@example.com.


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News from WTOP
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Mike Causey
Shows & Panels
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- The 2014 Big Picture on Cyber Security
- AFCEA Answers
- Ask the CIO
- Building the Hybrid Cloud
- CDWG/NetApp
- Connected Government: How to Build and Procure Network Services for the Future
- Continuing Diagnostics and Mitigation: Discussion of Progress and Next Steps
- Federal Executive Forum
- Federal Tech Talk
- The Future of Government Data Centers
- The Future of IT: How CIOs Can Enable the Service-Oriented Enterprise
- Government Perspectives on Mobility and the Cloud
- The Intersection: Where Technology Meets Transformation
- Maximizing ROI Through Data Center Consolidation
- Mitigating Insider Threats in Virtual & Cloud Environments
- Modern Mission Critical Series
- Moving to the Cloud. What's the best approach for me
- Navigating Tough Choices in Government Cloud Computing
- The New Generation of Database
- Reimagining the Next Generation of Government
- Satellite Communications: Acquiring SATCOM in Tight Times
- Targeting Advanced Threats: Proven Methods from Detection through Remediation
- Transformative Technology: Desktop Virtualization in Government
- The Truth About IT Opex and Software Defined Networking
- Value of Health IT
- Air Traffic Management Transformation Report
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- General Dynamics IT Enterprise Center
- Gov Cloud Minute
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- Homeland Security Cybersecurity Market Report
- National Cybersecurity Awareness Month
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Search Result
Search Tags: Shared services
New data could be difference-maker for move to shared services
OMB and Treasury have been working with the four federal financial management shared services providers to collect information on cost and performance. OMB Deputy Controller Norman Dong said the data will help agencies make true comparisons of the providers.
Tags: Norman Dong , technology , OMB , Lisa Schlosser , AGA , AFFIRM , shared services , financial management , Treasury , Jason Miller
OMB reworking financial system requirements to focus on outcomes, not inputs
The administration is expected to release a new directive in the coming weeks to update Circular A-127, which defines how agencies operate their financial systems. The new guidance is expected to open the market up to vendors and make it easier for agencies to transition to shared service providers.
Tags: technology , shared services , Adam Goldberg , Treasury , OMB , Keith Trippie , DHS , Gwynne Kostin , GSA , Kirit Amin , Commerce , Management of Change Conference , ACT-IAC , Jason Miller
'Uncle Sam's List' launched to boost awareness of shared services
The Federal Chief Information Officers Council's shared-services implementation guide describes the new database of more than two dozen offerings for agencies in the commodity and support service IT areas. The document also provides metrics to ensure shared services are meeting the agency's needs.
Tags: technology , OMB , CIO Council , shared services , Jason Miller , Uncle Sam
5 trends and hurdles for the future of effective financial management
From shared services and data-driven decision-making, to shrinking budgets and workforces, Federal News Radio's special report, Rise of the Money People, tracks the emerging trends in effective financial management at federal agencies, and the possible hurdles that stand in the way of saving even more money.
Tags: Rise of the Money People , financial management , shared services , workforce , Clarence Crawford , Deloitte , Peggy Sherry , DHS , Jack Moore
Bureau of Fiscal Service primes network for influx of new customers
Kim McCoy, the bureau's chief information officer, said she's looking at how best to pre-position resources to get new agency financial management customers on board more quickly.
April 11, 2013
Tags: technology , management , Kim McCoy , Bureau of Fiscal Service , Treasury Department , financial management , shared services , data analytics , Ask the CIO , Jason Miller , Rise of the Money People
Shared services becoming new normal in financial modernization
When it comes to saving money, shared services providers are the new "it" thing. As part of the special report, Rise of the Money People, Federal News Radio gets the inside scoop from the head of the Interior Business Center.
Tags: Interior Business Center , shared services , financial management , Joseph Ward , Esther Horst , In Depth , Francis Rose , Rise of the Money People
OMB to test agency readiness to move to financial shared services
Danny Werfel, the OMB controller, will issue a new policy in the coming weeks that will mandate agencies simplify their requirements before upgrading their general ledger systems. The policy also will require agencies to strongly consider one of the four federal shared service providers. OMB said it has learned lessons from the previous attempts to move agencies into these common financial management infrastructures.
Tags: technology , OMB , Danny Werfel , shared services , financial management , Treasury , CFO Council , Jason Miller , exclusive
CFOs remain tepid on financial shared services
An exclusive Federal News Radio survey of federal CFOs and deputy CFOs finds 55 percent of the respondents rated spending money more wisely as their top priority. But at the same time, 36 percent rated moving to the Internet Payment Portal or other financial management shared services as their fourth highest priority. CFOs also say they are using data to make better decisions and budget reductions, not sequestration, is their biggest concern.
Tags: financial management , CFO Council , Adam Goldberg , Treasury , OMB , Office of Financial Innovation and Transformation , shared services , sequestration , budget , CFO survey , In Depth with Francis Rose , Jason Miller , exclusive
Inside the Reporter's Notebook: GSA FAS, shared services and DHS contract awards
News and buzz in the acquisition and IT communities that you may have missed this week.
Tags: technology , acquisition , Jason Miller , cloud computing , OMB , DHS , GSA , Air Force , First Source 2 , industry , Small business contracting , shared services , financial management , Inside the Reporters Notebook
New contracts set EPA's roadmap toward IT centralization
Malcolm Jackson, the agency's CIO, said two new contracts for IT hardware and email will begin to transform the way EPA buys and uses technology.
November 29, 2012
Tags: technology , Malcolm Jackson , EPA , cloud computing , strategic sourcing , shared services , Interior Department , Ask the CIO , Jason Miller


text: Physiology (Scholarly Publications) http://hdl.handle.net/2262/134 Physiology (Scholarly Publications) 2014-10-02T14:29:50Z Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations http://hdl.handle.net/2262/70662 Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations DEV, KUMLESH Fingolimod (FTY720) is an oral therapy for relapsing remitting multiple sclerosis (MS) and targets sphingosine 1-phosphate receptors (S1PRs). FTY720 also rescues animals from experimental autoimmune encephalomyelitis (EAE), an animal model of MS. The protective effects of FTY720 in EAE are primarily scored manually by examining weight loss and limb paralysis that begins around 10-12 days after immunisation. To our knowledge, pre-clinical effects of FTY720 on animal behaviour early in EAE have not been explored. Here, we developed an automated behaviour monitoring system to examine the early effects of FTY720 on subtle pre-symptomatic behaviour of mice induced with EAE. Our automated home-cage monitoring system (AHC-MS) enabled non-contact detection of movement and ultrasonic vocalisations (USVs) of mice induced with EAE, thus allowing detection of subtle changes in mouse behaviour before paralysis occurs. Mice receiving FTY720 emit longer USVs and display higher levels of motor activity than vehicle-treated EAE mice before clinical symptoms become apparent. Importantly, this study promotes the 3Rs ethics (replacement, reduction and refinement) in the EAE animal model and may also improve pre-screening of potentially novel MS therapies. In addition, this is the first report showing the early effects of FTY720 in EAE which underscores its protective effects. PUBLISHED 2014-01-01T00:00:00Z Fingolimod Attenuates Splenocyte-Induced Demyelination in Cerebellar Slice Cultures http://hdl.handle.net/2262/70661 Fingolimod Attenuates Splenocyte-Induced Demyelination in Cerebellar Slice Cultures DEV, KUMLESH The family of sphingosine-1-phosphate receptors (S1PRs) is G-protein-coupled, comprised of subtypes S1PR1-S1PR5 and activated by the endogenous ligand S1P. The phosphorylated version of Fingolimod (pFTY720), an oral therapy for multiple sclerosis (MS), induces S1PR1 internalisation in T cells, subsequent insensitivity to S1P gradients and sequestering of these cells within lymphoid organs, thus limiting immune response. S1PRs are also expressed in neuronal and glial cells where pFTY720 is suggested to directly protect against lysolecithin-induced deficits in myelination state in organotypic cerebellar slices. Of note, the effect of pFTY720 on immune cells already migrated into the CNS, prior to treatment, has not been well established. We have previously found that organotypic slice cultures do contain immune cells, which, in principle, could also be regulated by pFTY720 to maintain levels of myelin. Here, a mouse organotypic cerebellar slice and splenocyte co-culture model was thus used to investigate the effects of pFTY720 on splenocyte-induced demyelination. Spleen cells isolated from myelin oligodendrocyte glycoprotein immunised mice (MOG-splenocytes) or from 2D2 transgenic mice (2D2-splenocytes) both induced demyelination when co-cultured with mouse organotypic cerebellar slices, to a similar extent as lysolecithin. As expected, in vivo treatment of MOG-immunised mice with FTY720 inhibited demyelination induced by MOG-splenocytes. Importantly, in vitro treatment of MOG- and 2D2-splenocytes with pFTY720 also attenuated demyelination caused by these cells. In addition, while in vitro treatment of 2D2-splenocytes with pFTY720 did not alter cell phenotype, pFTY720 inhibited the release of the pro-inflammatory cytokines such as interferon gamma (IFNγ) and interleukin 6 (IL6) from these cells. This work suggests that treatment of splenocytes by pFTY720 attenuates demyelination and reduces pro-inflammatory cytokine release, which likely contributes to enhanced myelination state induced by pFTY720 in organotypic cerebellar slices. PUBLISHED 2014-01-01T00:00:00Z Levels of S100B are raised in female patients with schizophrenia. http://hdl.handle.net/2262/70660 Levels of S100B are raised in female patients with schizophrenia. DEV, KUMLESH Background The neurotrophic factor, S100B, is released primarily from astrocytes, with serum and CSF levels of S100B reported as altered in schizophrenia. However, many of these reports are contradictory. Here, serum levels of S100B in schizophrenia and influence of age, gender, medication and illness severity were examined. Methods Serum S100B levels were measured in patients with schizophrenia treated with clozapine. Lifestyle, metabolic and illness severity parameters were correlated with S100B concentrations. Results Data showed raised serum levels of S100B in schizophrenia female patients, but not male patients, compared to controls. Correlation analysis demonstrated a positive association between S100B serum concentrations and BMI. Conclusions This study supports previous findings that adipocytes may contribute to S100B serum concentrations in females, in addition to astrocytes. This study also supports the hypothesis that metabolic effects of medication, lifestyle choices and the illness itself, may be contributing factors to altered levels of S100B. PUBLISHED 2013-01-01T00:00:00Z Age-associated dysregulation of microglial activation is coupled with enhanced BBB permeability and pathology in APP/PS1 mice http://hdl.handle.net/2262/67817 Age-associated dysregulation of microglial activation is coupled with enhanced BBB permeability and pathology in APP/PS1 mice LYNCH, MARINA ANNETTA; MINOGUE, AEDIN Aging adversely affects inflammatory processes in the brain, which has important implications in the context of disease progression. It has been proposed that microglia become dysfunctional with age and may lose their neuroprotective properties leading to chronic neurodegeneration. Here, we sought to characterize inflammatory changes in a mouse model of AD and to delineate differences between normal aging and those associated with disease pathology. A proinflammatory profile, characterized by upregulation of markers of classical activation was evident in APP/PS1 mice, associated with increased interferon (IFN)? concentration and dysregulation of mechanisms designed to limit the proinflammatory response. The data indicate that microglia are not less active with age but alter their phenotype; indeed changes observed in the deactivation state appear to relate to aging rather than disease pathology. We hypothesize that disruption of the BBB, in tandem with an enhanced chemokine profile, permits the infiltration of immune cells serving to reinforce classical activation of microglia through their enhanced responsiveness to IFN?. SUBMITTED 2014-01-01T00:00:00Z


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Infant Massage Instruction
Infant massage instruction is also available in the comfort of a mother's postpartum suite. Mothers can learn valuable hands-on techniques to help prepare for going home with baby. Benefits of massage for baby include:
- Allows baby to be more alert and interactive
- Improves sleep and awake patterns
- Supports infant-parent interaction
Ridgeview Spa Therapy is located adjacent to the Birthing Center at Ridgeview Medical Center in Waconia. Appointments can be made by calling Ridgeview Spa Therapy at 952-442-3187.


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so here's something I've been working on for awhile:
folding dragon wings in Second Life.
the reason they're special is because they're rigged to the arms of the avatar. therefore, they can be deformed organically with avatar animations. and I found a way to get the fingers to fold up, even without extra bones.
this is pretty fucking cool oiajdofijaoisdjfio
and they're the first fully animated mesh wings in SL, provided no one beats me to the punch. you can use all the normal animations with these and the wings will deform just like a standard arm. the webbing between the fingers squishes together with certain poses of the wrist, just like you'd expect a bat wing to fold up.
trying to get these done as soon as possible, along with commissions ; _ ;
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Chef Ted Stelzenmuller pairs the meat with cucumbers and a butternut squash pureé.
Fall is Chef Ted Stelzenmuller's favorite season, and he says October is a good time to cook rustic, family-style dishes.
We asked Stelzenmuller, executive chef/owner of Jack's Bistro in Canton, to create a seasonal dish for us, and he choose roasted rack of lamb with butternut squash purée.
"I purée the butternut squash because I love the texture of it," he says. "It acts as a sauce in this dish. It represents the fall beautifully."
Stelzenmuller is also a believer in presentation. For this dish, he spoons the purée onto a platter, then places the rack of lamb on top. He recommends composing the salad next to the lamb, layering the cucumber ribbons and twisting them to create height.
Roasted Rack of Lamb
with Butternut Squash Purée and Cucumber Salad
Rack of Lamb Serves 2
½ cup fresh bread crumbs
2 tablespoons minced garlic
2 tablespoons fresh chopped rosemary
2 teaspoons salt, divided
1 ¼ teaspoons black pepper, divided
4 tablespoons olive oil, divided
1 rack of lamb (7 bones)
1 tablespoon Dijon mustard
1. Set oven to 450 degrees. Move oven rack to the center position.
2. In a large bowl, combine bread crumbs, garlic, rosemary, 1 teaspoon of salt and ¼ teaspoon of black pepper. Toss with 2 tablespoons of olive oil to moisten mixture. Set aside.
3. Season the lamb all over with one teaspoon each of salt and pepper. Heat 2 tablespoons olive oil in a heavy oven-proof skillet over high heat. Sear lamb for 1 to 2 minutes on all sides. Set aside for a few minutes. Brush lamb with mustard. Roll in the bread crumb mixture until evenly coated. Cover the ends of the bones with foil.
4. Arrange the rack bone side down in the skillet. Roast in oven for 12 to 18 minutes, depending on the degree of doneness you want. Let it rest for 5 to 7 minutes, loosely covered, before carving.
Butternut Squash Purée
1 whole butternut squash deseeded, cut into 1-inch slices
2 tablespoons olive oil
¼ cup butter
¼ cup honey
2 tablespoons fresh chopped mint
1 teaspoon salt
1 teaspoon black pepper
1. Preheat oven to 450 degrees.
2. Drizzle the squash with olive oil and place in a single layer on a cookie sheet. Bake until just tender, about 18-20 minutes.
3. Reserve a slice of the roasted squash for the cucumber salad.
4. Combine all ingredients in a food processor and blend until smooth. Place in a mesh strainer and push the purée through.
Cucumber Salad
2 cucumbers
¼ pound Greek feta cheese
Reserved roasted butternut squash
1 tablespoon olive oil
½ teaspoon finely grated lemon rind
Salt and pepper to taste
1. Use a mandolin slicer to shave the cucumber as thinly as you can. Slice till you start seeing seeds, rotate the cucumber and continue slicing.
2. Combine all ingredients in a bowl and gently toss.


text:
Gare Joyce
If you enjoy reading and have a passion for junior hockey, the draft or the inner workings of NHL teams then Gare Joyce's new book FUTURE GREATS AND HEARTBREAKS is a must buy.
My introduction to Joyce came last spring when I found his blog online. Joyce had terrific info and he clearly was speaking to NHL scouts (a great line about Gagner for instance had him behaving like a 10-year NHL veteran, and that he was voted smartest player in an OHL coach's poll) and soonafter I read about his book coming out this fall.
Joyce was granted access to the 2006 Entry Draft process by the Columbus Blue Jackets. The insights offered into the exhaustive and yet incomplete work of an NHL team in draft preparation are eye opening to say the least. I won't spill the beans here, but suffice to say that Joyce gives us a glimpse of the scouting process in pro hockey that runs parallel to baseball's "saw him good" brigade with very little Bill James math-sussing.
The book is an exceptional read, both because of the content (I was disappointed when finished, only because there's not another one to look forward to) and the author's writing style. It felt like I was getting a series of emails from someone in the hockey industry updating me on the 2006 and 2007 drafts, with stuff you just can't get from your typical hockey writer (there's probably 20 things in the book that are what I would call big facts, things that were important about the 2 drafts that I didn't know at the time).
For Oiler fans lots to like including a hilarious story about Lorne Davis that made me laugh out loud. Some (not a lot) of info on Sam Gagner and a few other items along the way.
One final note: kudos to the Blue Jackets for granting Joyce a chance to see into an area of the sport many of us have a strong interest in without ever having a chance to be a part of it. If I'd owned the book on draft day, the Cherepanov and Esposito free falls would have been easily explained.
Good book Joyce.


text:
What's going on, Albuquerque?
Cafe Bella Coffee is excited to offer this great local acoustic talent at our venue. Come hear the live sounds of Gregory James. Singer/Songwriter Friday Dec. 7th 7pm-9pm no cover.
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42 U.S. Code § 1320c–7 - Application of this part to certain State programs receiving Federal financial assistance
(a) State plan provision that functions of quality improvement organizations may be performed by contract with such organization
A State plan approved under subchapter XIX of this chapter may provide that the functions specified in section 1320c–3 of this title may be performed in an area by contract with a quality improvement organization that has entered into a contract with the Secretary in accordance with the provisions of section 1395y (g) of this title.
(b) Federal share of expenditures
In the event a State enters into a contract in accordance with subsection (a) of this section, the Federal share of the expenditures made to the contracting organization for its costs in the performance of its functions under the State plan shall be 75 percent (as provided in section 1396b (a)(3)(C) of this title).
Source(Aug. 14, 1935, ch. 531, title XI, § 1158, as added Pub. L. 97–248, title I, § 143,Sept. 3, 1982, 96 Stat. 390; amended Pub. L. 112–40, title II, § 261(a)(2)(C),Oct. 21, 2011, 125 Stat. 423.)
Prior Provisions
A prior section 1320c–7, act Aug. 14, 1935, ch. 531, title XI, § 1158, as added Oct. 30, 1972, Pub. L. 92–603, title II, § 249F(b), 86 Stat. 1437; amended Oct. 25, 1977, Pub. L. 95–142, §§ 5(d)(1), 22 (a), 91 Stat. 1185, 1208; Dec. 5, 1980, Pub. L. 96–499, title IX, §§ 902(a)(3), 931(h), 94 Stat. 2613, 2634; Aug. 13, 1981, Pub. L. 97–35, title XXI, §§ 2113(e), 2121 (g), 95 Stat. 794, 796, related to review approval as a condition of payment of claims, prior to the general revision of this part by Pub. L. 97–248.
2011—Subsec. (a). Pub. L. 112–40substituted "quality improvement" for "utilization and quality control peer review" in text.
Effective Date of 2011 Amendment
Amendment by Pub. L. 112–40applicable to contracts entered into or renewed on or after Jan. 1, 2012, see section 261(e) ofPub. L. 112–40, set out as a note under section 1320c of this title.
The table below lists the classification updates, since Jan. 3, 2012, for this section. Updates to a broader range of sections may be found at the update page for containing chapter, title, etc.
The most recent Classification Table update that we have noticed was Tuesday, August 13, 2013
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Detroit's National Action Network is expected to head to Lansing Tuesday to lobby for lawmakers to repeal the state's stand-your-ground law, and to start a petition drive to put it on the November ballot. "We will make sure that on this November ballot that we get the opportunity to strike a blow for justice for Trayvon Martin, to strike a blow for justice for Renisha McBride," says Rev. Charles Williams of the Detroit National Action Network. ALSO SEE: More on the shooting death of Renisha McBrideBut this plan to repeal Michigan's version of the stand-your-ground law is not sitting well with many gun owners, especially those who have had to use them in self defense.For example is Darrell Standberry. "If it wasn't for stand-your-ground law, right now I would be in jail," he says. He shot and killed a man who pulled a gun on him while stealing his car."I turned back and looked and he was already in the driver's seat of my vehicle. ... He turned around and looked and [saw] that I was still standing there, and that's when he reached in his pocket to pull out his weapon, and I pulled out my weapon and I fired one shot," says Standberry. ALSO SEE: Detroit homeowner shoots, kills 1 of two intruders"We believe in the second amendment. We believe in defending yourself. ... What we do not believe is in a law that gives you a license not to walk away," says Rev. Williams. That's the key element of the law - not having to retreat when you feel your life is in immediate danger."To me, it comes down to a basic Second Amendment right and stand your ground, as far as I'm concerned, is already covered under that," says Pete Letkemann, a supporter of the law.
KMSP-TV11358 Viking DriveEden Prairie, MN 55344
Phone: (952) 944-9999Fax: (952) 942-0455


text:
Gothic Peak Additions and Corrections
[ Post an Addition or Correction ]
|Untitled Comment
Voted 10/10
|This can be a tough hike day hike but worth the burn. It starts out crazy steep in the forest, but the trail is clean and smooth... This is the "easy" part (you're a third of the way to the basin). Once you exit the forest, it gets rough in spots with lots of rocks and roots to look out for. The trail hugs the mountain for a little bit and the views open up dramatically. You'll also see that you still have a long way to go and it's up, up, up... Once you enter the basin though, you're instantly rewarded. It's huge!! And the terrain is striking... it's like you're on another planet. A picture just can't do it justice.
|Posted Aug 10, 2005 2:49 am


text:
Birchwood Casey® Gun Stock Sealer & Filler
Item # WX2-169570
- Google+
This item cannot ship via any of our Next Day or Second Day Express delivery methods.
Shipping restrictions apply to this product under some jurisdictions. Known age, state and local shipping restrictions are applied at checkout and may result in changes to an order. PLEASE NOTE: We do not accept returns of Ammunition for safety reasons. NEVER use any Ammunition unless it is specifically designed for your firearm.
This item cannot ship via any of our Next Day or Second Day express delivery methods.
This item cannot ship to Canada.
This item cannot ship internationally.
- Details & Specs
Birchwood Casey® Gun Stock Sealer & Filler. Seals out moisture and fills the pores in one easy step!
Produces a clear, rich color without grain clouding or smearing. A clear sealer and filler lets you choose your favorite stain or leave the wood in a natural tone. Use Sealer & Filler as the first step to a beautiful gun stock finish. Easy-to-use and dries fast. 3 ozs.
Get yours ONLINE for easy, affordable upkeep!
- Reviews
Customer Reviews
Casey's has good products.
Works good if used as directed.
Glad to find this product on SG because it cost almost double locally at the shops. This will make my refinishing project turn out great!!
I use this with the Birchwood Casey Tru-Oil finish and get good results. They should include this in their stock finish kits but for some reason they don't. Follow th simple instructions and you will get good results. Mike
worked out great was everything that it was said to be
I have a severely damaged rifle stock to fix, so I'm going to take it down to bare wood to repair it. I haven't used this stuff before, but I'm going on my experience with furniture repair and guessing I'll be needing something like it.
You May Also Like
Birchwood Casey® Tru - Oil® Gun Stock FinishBuyer's Club $4.94 Non-Members $5.49
Birchwood Casey® Complete Tru - Oil® Gun Stock Finish KitBuyer's Club $12.59 Non-Members $13.99
Birchwood Casey® Deluxe Perma Blue® Liquid Gun Blue & Tru - Oil® Gun Stock Finish KitBuyer's Club $17.99 Non-Members $19.99


text:
|Good - 1168 reviews
With a stay at Globales Reina Cristina in Algeciras, you'll be near the beach and minutes from Algeciras Harbour. This 4-star hotel is within the vicinity of Cathedral of the Holy Trinity and 100-Ton Battery. Make yourself at home in one of the 168 air-conditioned guestrooms. Rooms have private balconies. Complimentary wireless Internet access keeps you conn...
Overall Rating - Good - 1168 reviews
|Excellent - 1203 reviews
With a privileged location next to the Alcornocales Natural Park, Hotel Mesón de Sancho is a 3-star hotel in Tarifa, the easternmost end of the Peninsula and a renowned windsurfing destination. It is within an hour drive from Jerez Airport, and a few minutes from Tarifa and Algeciras by car. Thanks to its situation, this charming budget hotel is an excellent...
Overall Rating - Excellent - 1203 reviews
|Excellent - 330 reviews
The NH Campo de Gibraltar is a four star hotel located in the industrial area of palmones. Situated a few minutes away from the center of Algeciras, as well as Los Barrios, La Línea or Gibraltar. The famous beaches of Tarifa, located at the southernmost tip of the Iberian Peninsula, are only a 25-minute drive away, or you can catch a ferry to Tangiers for a...
Overall Rating - Excellent - 330 reviews
|Excellent - 1 reviews
In the heart of La Linea de la Concepcion, Asur Campo de Gibraltar is close to Victoria Stadium and Casemates Square. This 4-star hotel is within close proximity of Military Heritage Centre and Great Siege Tunnels and Tower of Homage. Make yourself at home in one of the 225 air-conditioned rooms featuring minibars. Rooms have private balconies. Satellite pro...
Overall Rating - Excellent - 1 reviews
Excellent 9.6
Within walking distance of Gibraltar, great breakfast with a lot of options, big/well designed hotel. Room had a view of the rock of Gibraltar
|Okay - 1 reviews
Overall Rating - Okay - 1 reviews
Okay 4.6
La organización del mobiliario y el mobiliario nuevo
El aire no funcionaba acorde a su temperatura , las habitaciones colindantes al ascensor. La recepcionista no tiene ni idea de las habitaciones del hotel o nos engañó volviendo a cambiar la habitación a otra con ascensor colindante La mampara de la bañera demasiado corta para su bañera y la presión del agua No huele a una buena higiene en el baño , no da sensación de higiene y limpieza en el baño
|no reviews
|Excellent - 179 reviews
Experience sprawling greenery and endless tranquility at the Hotel Almenara in Sotogrande. Located in the southern Spanish resort of Sotogrande, the hotel is surrounded by the 27-hole Almenara golf course. Designed by Ryder Cup champion and renowned golf course architect, Dave Thomas, Almenara is a destination celebrated by golf enthusiasts the world the ove...
Overall Rating - Excellent - 179 reviews
|Excellent - 220 reviews
Located in San Roque (Sotogrande), Club Maritimo De Sotogrande is close to Club de Golf La Canada and La Duquesa Castle. This 4-star hotel is within the region of La Duquesa Golf Course and Dona Julia Golf Club. Make yourself at home in one of the 41 air-conditioned rooms featuring minibars and flat-screen televisions. Windows open for fresh air and sea view...
Overall Rating - Excellent - 220 reviews
|no reviews
Vime Octavio is a modern hotel located in the heart of Algeciras. It is ideally positioned opposite the main railway station of Algeciras and very close to the port with a direct access to the motorway Cadiz-Malaga. The hotel is approximately 2 Km from the beach and 127 Km from Cadiz city centre The hotel offers 77 cosy rooms all of which are spacious and of...
|Good - 154 reviews
The magnificent four-star NH Sotogrande hotel is located in the heart of Sotogrande, along the popular Costa del Sol in Andalusia. Near the beautiful beaches of the Mediterranean, yet with easy access to the motorway and surrounded by some of the best golf courses in Spain, the hotel is a wonderful place to enjoy outdoor activities of all kinds. The 1997 Ryd...
Overall Rating - Good - 154 reviews
|Good - 210 reviews
When you stay at Hotel Alborán Algeciras in Algeciras, you'll be close to Algeciras Harbour. This hotel is within the vicinity of The Convent and Victoria Stadium. Make yourself at home in one of the 79 air-conditioned rooms featuring minibars. Complimentary wireless Internet access keeps you connected, and satellite programming is available for your enterta...
Overall Rating - Good - 210 reviews
Excellent 10.0
Location and convenience to ferries, exceptionally friendly staff who were very informative, helpful and gracious.
Nothing. Everything was above par.We were heading to Algeciras to catch a ferry the next day and chose this hotel for it's convenience. The hotel was nice, the staff exceptionally helpful and friendly and the meal we had that eveing was delicious, again, with very nice service. I would definitely stay again if I were in the area.
|Excellent - 268 reviews
Overall Rating - Excellent - 268 reviews
|Good - 240 reviews
CITYMAR MEDITERRANEO is located in the city of La Linea facing the Rock of Gibraltar and the African Coast. It is only a few meters away from the sea. The intensity of light features the landscape and gives name to a region known as Costa de la Luz. Light beautiful beaches of fine golden sand and fishing towns with an ancient sea tradition are the identity...
Overall Rating - Good - 240 reviews
|Excellent - 204 reviews
When you stay at Montera Plaza in Los Barrios, you'll be within the vicinity of Algeciras Harbour. This 4-star hotel is within the region of Cathedral of the Holy Trinity and The Convent. Make yourself at home in one of the 64 air-conditioned rooms featuring minibars. Rooms have private balconies. Conveniences include phones, as well as safes and desks. Take...
Overall Rating - Excellent - 204 reviews
|Excellent - 753 reviews
Overall Rating - Excellent - 753 reviews
Excellent 10.0
everything was just outstanding
nothe breakfast is the best and great price
Excellent 10.0
When researching various lodgings thru-out Spain and Portugal you never are quite sure what you may get. The Hotel Jerez was wonderful. It was a convent that has been converted into a hotel, which is in a good location. The staff was very helpful in responding to any questions or problems. They even gave us keys to a few rooms so we could pick the room we wanted. Breasfasts were excellent, choices were plentiful and tasty. You need to try the potatoe tortilla (yummy). Hotel was very clean, quiet, comfy. If we ever get back to Jerez, the Hotel Jerez is a definite place for us to stay.


text:
Dylan LeBlanc (born March 9, 1990 in Shreveport, Louisiana) is an American singer-songwriter. LeBlanc hails from Shreveport, LA, but currently resides in Muscle Shoals, AL.
Dylan LeBlanc is an American musician and artist. Born in Shreveport, Louisiana, LeBlanc began performing at age Fifteen. In Shreveport, LA and Muscle Shoals, AL he began performing at local venues. From a young age, LeBlanc watched his father perform at various clubs and bars. He became intrigued with musicianship and the way of life. At the age of Nineteen after parting ways with the band Abraham he acquired a vast amount of original material. Then, he was signed by Rough Trade Records who released his first album Pauper's Field.
At infancy LeBlanc's maternal mother and father divorced. Until the age of nine, LeBlanc lived with his mother in Blanchard, LA; a small town in the northeast corner of Shreveport. Working full-time cleaning houses, LeBlanc's mother raised Dylan and his two siblings. At the age of ten, LeBlanc relocated to Muscle Shoals, AL so his father could pursue his musical career as a professional country music songwriter. In Muscle Shoals, AL, LeBlanc acquired a unique musical education. He spent late nights watching musicians record at the studios where his father played on sessions for songs that he wrote.


text:
Barbara Walters 'weak and tired'
Barbara Walters too 'weak and tired' to return to 'The View' after suffering a concussion during a fall last month and will spend at least three more weeks recovering at her home
Barbara Walters is feeling ''weak and tired'' after being released from hospital.
The broadcaster and host of 'The View' was discharged last week after suffering a concussion from a fall at a pre-inauguration party for President Barack Obama in Washington, D.C. last month and was also diagnosed with chicken pox, but she plans to spend at least three more weeks recovering at home in New York.
The 83-year-old TV veteran phoned into the ABC chat show on Wednesday (06.02.13) and told her colleagues: ''I had a temperature and I had the chicken pox and didn't know it.
''So when I was in Washington for the inauguration weekend, I fainted at the British Embassy. If you're going to faint, it's a very elegant place to faint. And I hit my head and had six stitches, in addition to the chicken pox. I had been in somebody's company who had the shingles and I got the chicken pox from them. But, I also got a concussion.
''So I have been a little weak. I am not in any pain. I'm not scratching too much ... I'm not itching away! But I do feel just sort of weak and tired and I probably won't be back on the program for about three weeks.''
Barbara, a respected TV journalist, created and co-hosts 'The View' as well as her annual '10 Most Fascinating People' special, which attracts millions of viewers.
entertainment videos
Nick Cannon was presented an award from Toni Braxton at the Lucky for Lupus Celebrity Poker Tournament, as many other stars like Michael B. Jordan, Ver... More Nick Cannon was presented an award from Toni Braxton at the Lucky for Lupus Celebrity Poker Tournament, as many other stars like Michael B. Jordan, Verne Troyer, Shannon Elizabeth and Tito Ortiz all tossed in chips to fund a good cause.
Date 19/9/14, Duration 1:30, Views 682
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What Are the Warning Signs? Depression and Suicide
Children's Health Council
Wednesday, April 9, 2014 from 6:30 PM to 8:00 PM (PDT)
Palo Alto, CA
Trying to Understand Anxiety & Depression - A Series
These days anxiety is the number one problem interfering with kids' emotional well-being. Anxiety can also be combined with attention or learning problems. Learn how to understand your anxious child's reactions, how to respond and how to help your youngster with tools for success. Dr. Ramsey Khasho's knowledgeble team provides help and direction. All ages.
Three classes in this series will discuss Anxiety, Depression and related issues. Please register for each class separately.
April 9: What Are the Warning Signs? Depression and Suicide
At Children's Health Council, we believe there is a world of promise and potential in every child. Using a personalized approach, we help your children become happier, more resilient and more successful.
Our mission is to help children with ADHD, LD, Anxiety & Depression and Autism Spectrum Disorder (ASD) thrive by promoting Social Emotional Learning, Academics, Executive Functioning and Physical Development.
Our Center, two schools and Community Clinic serve families in the Silicon Valley as well as the greater San Francisco Bay Area.
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Damien S. K. Samways
Assistant Professor
Department of Biology
210 Science Center
Clarkson University
PO Box 5805
Potsdam, NY 13699-5805
E-mail: firstname.lastname@example.com
Phone: 315-268-7851
Fax: 315-268-7118
Google Scholar Page:
Education: Ph.D., Department of Pharmacology, University of Bristol, (2003)
Courses Currently Taught: BY460 Neurobiology
BY360/BY362 Comparative Physiology
BY452 Pharmacology
Research Interests
Ligand-gated cation channels are specialized membrane spanning proteins that open and form an cation permeable pore in response to binding by a specific chemical ligand. These transport caions, such as Na+ and Ca2+, into the cell, which subsequently regulate nerve and muscle cell excitability and influence numerous Ca2+-dependent processes including secretion, contraction, gene expression and cell survival.
My current research interest is in the structure, function and regulation of Ca2+ permeable ligand-gated ion channels known to be involved in pain sensation, including the ATP-gated P2X receptors and the capsaicin-sensitive TRPV1 receptors responsible for mediating the burning sensation associated with noxious heat and spicy food. Understanding the molecular basis of ion channel function in human cells is an important step towards designing new drugs capable of targeting these proteins for therapeutic purposes.
Publications (last 5 years)
Z. Lin, P. Perez, Z. Sun, J.J. Liu, J.H. Shin, K.L. Hyrc, D.S.K. Samways, T.M. Egan, M.C. Holley, J. Bao (2012). Reprogramming of single-cell-derived mesenchymal stem cells into hair cell-like cells. Otol Neurotol. 2012 Dec;33(9):1648-55.
D.S.K. Samways, B.S. Khakh, and T. M. Egan (2012). Allosteric modulation of Ca2+ flux in ligand-gated cation channel (P2X4) by actions on lateral portals. J. Biol. Chem. Mar 2;287(10):7594-602
D.S.K. Samways and T. M. Egan (2011). Calcium-dependent decrease in TRPV1 conductance. Pflugers Arch. Nov;462(5):681-91.
D.S.K. Samways, B. Khakh , S. Dutertre , T. M. Egan (2011). Preferential use of unobstructed lateral portals as the access route to the pore of a human P2X receptor. Proc. Natl. Acad. Sci. USA. Aug 16;108:13800-5.
E. Toulme, A. Garcia, D.S.K. Samways, T.M. Egan, M.J. Carson, and B.S. Khakh (2010). P2X4 receptor specificity, functional properties, trafficking and pharmacology of upregulated P2X responses in activated cerebellar microglia. J. Gen. Physiol. 135, 333-353
D.S.K. Samways, A.B. Harkins and T.M. Egan (2009). Native and recombinant ASIC1a receptors conduct negligible calcium entry. Cell Calcium. 45, 319-25
J.C. Scatizzi, M.Mavers, J. Hutcheson, B. Young, B. Shi, R.M. Pope, D.S.K. Samways, J. A. Corbett, T.M. Egan, and H. Perlman (2009). The cyclin dependent kinase domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages. Euro. J. Immunol. 39,820-5


text:
Interview with Ferenc Horváth
Ferenc Horváth
What was the key event in 2011?
2011 was the start of MOL Group DownstreamRefining and Marketing, Retail and Petrochemicals integration. The Division's extended value chain operates an enormous number of assets. Under this significantly improved arrangement, our goal now is to build on the high performance and multinational experience base of previous years. The fundamental requirement of the three main Business Units (Refining & Marketing, Petrochemicals and Retail) is to be the most effective in their own areas and, in addition, work together with Supply Chain Management leadership to achieve optimal DownstreamRefining and Marketing, Retail and Petrochemicals operations. It is a challenging process, but in MOL Group we have been working in a multinational environment for years and have a lot of experience in strengthening cooperation between organisations and employees. Of course there has already been strong cooperation between the three big units, but now it's getting more focused with synergies being explored and efficiency being improved.
How does MOL see the currently unfavourable external environment and industry profitability in general?
Unfortunately, hard times are upon us. Compared with 2010, in 2011 our 5 refineries alone generated USD 350 million additional expenses due to increased crude oil prices and growing purchased energy costs. Furthermore, both fuel and petrochemicals sales margins decreased. Although most consumers only face higher retail prices, it is not a favourable situation for producing companies anyway. As a consequence of the financial crisis and the factors I have just mentioned Europe still has significant refining overcapacity, markets and demand for almost every one of our products is shrinking. Financial figures for the second half of 2011 already show losses at nearly every European refinery. In 2011 Europe witnessed significant refining overcapacity and low utilisation rates. Around 10 refinery shut down and a further 20 operations will potentially be sold or shut down. The willingness to acquire is, of course, rather lukewarm in such a business environment.
What could the response be to these challenges? What is the outlook for the long term?
Our goal is to stay among the leaders in the present race and come out of the crisis strengthened by it. To achieve this, in the short term, a paradigm shift is needed to increase DownstreamRefining and Marketing, Retail and Petrochemicals profitability. Our newly- established "New DownstreamRefining and Marketing, Retail and Petrochemicals 2012-2014" programme focuses on this change, combining as it does all our efforts and actions through the value chain to increase efficiency. On the other hand, long-term global predictions have strengthened our opinions about changing trends in motor fuel demand. Our current asset structure with its selective investments, our focus on production complexity, flexibility and efficiency improvement actions coupled with GDP growth potential and possibly greater car penetration in the region give us grounds for confidence in the future. It is not by chance that the pillars of our DownstreamRefining and Marketing, Retail and Petrochemicals directions are our regional commercial strategy, the enhancing of operating efficiency and the exploitation of organic and inorganic growth potential.
Can you highlight some of the key actions and projects which will contribute to achieving your targets?
Every business, indeed every country, just like MOL Group, has a mission. Our business objective is to maintain our strong position in the region by maintaining and strengthening our wholesale and retail positions in the most profitable domestic markets and increasing our role and position in countries near MOL Group refineries i.e. Romania, the Czech Republic, Slovenia, Austria, Serbia and Bosnia-Herzegovina.
We also aim to execute some selective investment projects such as the recently approved ca. EUR 100 million butadiene project which will produce sales of a highly profitable product while simultaneously improving the efficiency of internal product flows. The new ca EUR 260 million LDPELow density polyethylene plant and steam cracker reconstruction project will maintain integration of our refining and petrochemicals businesses and ensure the production of nearly 30 types of polyethylene to appeal to new customers and create new markets in Europe.
What is the future outlook of INA?
The main task is still to support our Croatian partner become an efficiently functioning, profitable DownstreamRefining and Marketing, Retail and Petrochemicals market player. To reach this goal, we still have a lot to do but I think we are definitely on the right track.
Compared to 2010, we managed to increase our share of motor fuel sales, worth mentioning in a country which also has sea-borne supply channels. De-sulphurized products meeting EU quality and environment protection requirements opened channels to European markets.
As far as upcoming years are concerned, the most important things for INA will be economical growth and on-going efficiency improvements, which is also valid for the MOL Group portfolio as a whole, but for Croatia in particular. Our refining assets complement each other so that transfers between Rijeka and Sisak allow us to minimize low-value product output and maximize production of marketable diesel. We have to continue refinery modernisation. As part of this, we are planning a residue upgrade project at our Rijeka refinery, improving its product yield structure in favour of higher margin products.
Product costs have to be lowered by continuously improving production unit and logistics system efficiency, also keeping an eye on energy utilisation including our own in-house consumption of crude oil.
How is Sustainable Development connected to this progress?
We are highly committed to Sustainable Development principles. Since integration, our intellectual capital flourishes and the DownstreamRefining and Marketing, Retail and Petrochemicals Division will pay even more attention to Research & Innovation to make the best of this opportunity. Several projects in this area are underway at the moment, including waste-based bio-component blending, second generation bio-diesel and algae research, chemically stabilised rubber bitumen production, the investigation of the feasibility of biogas plants and waste plastics-based fuel production.
MOL Group at a glance
Historical summary of financial information
Key group operating data
Management Discussion and Analysis
Gas Midstream
Corporate Governance
Integrated Risk Management Function
Corporate information
Table of contents
Contact information


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Daily Devotions
Daily devotions can help you keep the Word of God a constant presence in
your life. The Christian devotions you'll find here offer time for personal
reflection, an oasis of quiet in a busy life, and a way to feel inspired and
closer to God. These Bible devotions, beautiful reminders of God's love, provide inspiration at the beginning of your day and peace at day's end.
More Daily Devotions
Today's Daily Reflection
Recent Daily Devotions
A Labor Day tradition leads this devotional writer to examine her role in Jesus' Kingdom.
A Labor Day devotion to remind you of the restorative power of stopping a moment and resting.
The next time a biting remark comes to mind say this verse and bite your tongue instead.
Do you use the holiday as a gift of time to spend getting things done?
We each have an inner odometer that measures the distance we must travel from inner discomfort to peace.
Best-loved devotional writer Elizabeth Sherrill recounts an incredible story of why we should always live in the present in this preview of Daily Guideposts 2015.
This preview of Daily Guideposts 2015 explores faith, prayer, luck and the grace of God.
A preview from Mornings with Jesus 2015 to help you see the difficulties as important milestones on life's path.
A preview from Mornings with Jesus 2015 to help you discover the precious gifts each of us brings to the world.
Scripture and tips for nights when you can't sleep.
Peppers, onions, cucumbers, squash–and a kindness meant to be passed along.
Use this devotion and faith step to help you conquer your fears.
Do you block out time for your most important priority–spending time with your Heavenly Father?
How to handle a problem so that it doesn't hang around and morph into something else!


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On special today we are serving ham and smoked gouda with lettuce, red onion, roasted red peppers and horseradish mayo on a toasted bulkie.
Today's soups are Roasted Red Pepper & Smoked Gouda Bisque and Potato & Bacon
Join our facebook page to be in the know on whats going on @ Giacomo's
Giacomo's is one of downtown Bangor's favorite dining destinations, featuring Maine roasted coffee, an espresso bar, panini sandwiches, and an impressive wine and beer list.
Located in the heart of historic Bangor, with a panoramic view of downtown, Giacomo's warm and inviting setting includes both indoor and outdoor seating. Whether you're looking for an espresso and pastry, a warm and satisfying panini sandwich, or a glass of wine and a cheese plate, you will find what you're looking for at Giacomo's.
Our café also offers great music and free wi-fi, and our custom take-out platters and catering options are perfect for all of your entertainment needs.
Giacomo's has the best sandwiches in town. Their gourmet menu is now expanding to include pizza !


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Next, you'll be asked to connect with Twitter. Rest assured, we will never send a tweet from your account
without your permission.
We will send you an email with an invite soon.
Pats Agree To 2-Year Deal With Former Raiders DT Tommy Kelly http://t.co/Y5G3v4Ca6U
Ex-Raider Russell's Comeback Effort Draws Legitimate Interest
Raiders Release Former 1st-Round Pick LB Rolando McClain
See what's Trending Now about Raiders


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NEW YORK (AP) - Pittsburgh pitcher Mark Melancon has been picked as a replacement for the NL All-Star team, giving the Pirates five players in the game for the first time since 1972.
NL manager Bruce Bochy also selected Sergio Romo, his San Francisco Giants closer, as a replacement pick Sunday. Pirates pitcher Jeff Locke and Washington Nationals pitcher Jordan ZImmermann, both on the original NL All-Star roster, are hurt and will miss Tuesday's game at Citi Field.
Baltimore pitcher Chris Tillman was picked by AL manager Jim Leyland of Detroit to replace Tigers ace Justin Verlander, who started Sunday. Under baseball's labor contract, pitchers who start on the Sunday before the All-Star game may opt not to participate. Verlander was the starter and loser of last year's All-Star game at Kansas City.
Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Southern Living APRIL 2008
1. Combine seeds in a shallow dish. Brush dough loaf with egg white. Roll top and sides of dough loaf in seeds. Place, seam side down, on a baking sheet. Cut and bake dough loaf according to package directions.
Go to full version of
Three-Seed French Bread recipe


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Police in Cobb County say a woman has died after being shot overnight during a road rage incident off of Wade Green Road in Kennesaw. They say two female drivers got into an altercation along Shiloh Road, and that led to a shooting in the parking lot at a nearby apartment complex. Investigators say the incident started at about 2 a.m., and soon moved to the parking lot of the Shiloh Green Apartments, which is a gated complex. Authorities aren't sure how the two drivers got inside. At some point, police say the argument turned physical, and a gun was pulled and 22-year-old Kim Kilgore was shot. She was taken to the hospital, where she later died.Authorities are still investigating the incident. They say they believe the women were involved in a road rage incident, but it's possible they may have known each other.Investigators say they are looking for a black Ford Mustang, and/or a silver Chevrolet Cavalier in connection to the incident. They say it's possible other people were involved.Kilgore was a student at Kennesaw State University, where she had been a member of the Gamma Phi Beta sorority, FOX 5 has been told.
KRIV FOX 264261 Southwest FreewayHouston, TX 77027Phone: (713) 479-2801Fax: (713) 479-2859


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It's not breaking news that the United States began to feel like a more dangerous place after 9/11. The Gallup Poll has reported that roughly 9 in 10 Americans have worried about future terror attacks on US soil ever since. For many people, that general sense of dread got even more intense after the Boston Marathon bombings. In late April, Gallup said 51 percent of Americans surveyed believed another attack could happen soon, up from 38 percent about a year and a half earlier. Yet the reality is that we're far safer than we often feel.
In late 2012, I published a study in the journal Studies in Conflict & Terrorism that set out to estimate how many jihadi plots are in the works and how long it takes would-be terrorists to plan them. I knew that in the anxious weeks and months after a terrorist attack, it could feel as if we were under siege — as if there were bombs waiting to go off around every corner and under every subway seat. But the results of my analysis suggest otherwise: On average, at any one time there are fewer than three hidden terror plots being planned across the country.


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Condition 2 products are a terrific value and you can buy with confidence knowing
our 60-Day Satisfaction Guarantee on instruments and 30 days on accessories applies to this used product.
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Yamaha DSR115 Active LoudspeakerThe DSR115 Active Loudspeaker features an ideal combination of advanced digital sound processing and the latest acoustic technologies for Integral Digital Tuning, plus Yamaha's D-CONTOUR (Dynamic-CONTOUR) multiband dynamic processing for Intelligent Dynamic Control. The DSR115 is loaded with 2 Class-D amplifiers with a PFC (Power Factor Correction) switching mode power supply. One amplifier deliver 850 watts to a premium grade 12" neodymium woofer with 3" voice coil and a second amplifier supplies 450 watts to a large 2" high purity titanium diaphragm, neodymium, high-frequency compression driver. A LTBD (Long Throw, Broad Dispersion) Constant Directivity Waveguide Horn spreads the sound across 90° x 60°. The DSR115 has an impressive maximum SPL of 134dB peak.FIR-X tuningThe digital crossover networks use high-order FIR (Finite Impulse Response) filters providing linear phase response. Yamaha's proprietary FIR-X tuning technology simultaneously optimizes frequency and phase response, whilst adjusting the time alignment between the HF and LF transducers. The end result is substantially higher sound quality than can be achieved with conventional analog crossovers.High Power DSP and 24-bit Discrete ADCs and DACsAll signals are precisely processed by a 48-bit internal processing, (76-bit accumulator), high performance processor for optimum sound quality. The DSR Series speakers employ high-precision discrete ADCs and DACs with superior S/N ratio and dynamic range. The analog signal is transmitted on dual channels, converted to digital and summed inside the processor. By using this algorithm, an approximately 3dB improvement in S/N ratio was realized. FIR-X tuning provides for the smoothest possible crossover transitions.D-CONTOUR (Dynamic-CONTOUR)The D-CONTOUR multiband dynamic processor constantly monitors the amplifier output levels and adjusts the control system. This in turn varies the amount of boost in each frequency band, providing an ideal balance of dynamic sound with consistent clarity at all volume levels. D-CONTOUR can be turned on or off depending on the acoustic environment and type of sound desired.1300W (LF 850W, HF450W) High Power, High Sound Quality Class-D AmplifiersYamaha's next-generation Class-D amplifiers deliver as much as 1300W of power with precision damping for tight and crisp sound from compact, lightweight modules. Through the ideal combination of amplifiers, transducers, and DSP, the DSR Series loudspeakers provide the highest levels of power in their class, while maintaining precise dynamics and sound reproduction. Efficiency is such that convection cooling is all that is necessary, eliminating the need for fans.Full Resonance Switching Mode Power Supply with PFC (Power Factor Correction)The DSR Series employs a Yamaha-developed high-efficiency switching mode power supply with PFC. The full resonance switching method uses both voltage resonance and current resonance, creating a clean power supply waveform with minimal high frequency noise. PFC harmonizes the phases of the load current and power supply voltage, maximizing power output and ensuring stable operation under severe conditions. This clean, efficient power supply enables the entire speaker system to achieve its full performance potential.3-Way Fail-Safe ProtectionTo ensure the highest possible reliability, the DSR Series employs many of the same protection functions used in Yamaha's top-class TXn Series professional power amplifiers. These functions protect all aspects of the power supply, power amplifier modules and transducers so that they can operate to their full potential while ensuring fail-safe operation even under the most severe conditions.The DSR115 performs as main PA and is stand and pole mountable, with a 35mm pole socket. M10 rigging points allow for suspended installation.Note: The limited warranty on DSR-Series loudspeakers is extended to five years. In addition, all qualified DSR purchasers, thus far, are also retroactively covered by this extension, from the date of original sale.
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Northern Michigan Forum-Share Events, Travel Ideas, Photos, Videos
Time: November 18, 2012 from 9am to 11am
Location: Timber Ridge Rv & Recreation Resort
Street: 4050 Hammond Rd. East
City/Town: Traverse City
Website or Map: http://www.timberridgeresort.…
Phone: 231.947.2770
Event Type: and more
Organized By: Timber Ridge Rv & Recreation Resort
Latest Activity: Nov 18, 2012
Export to Outlook or iCal (.ics)
Timber Ridge hosts a special weekend of shopping and movies just for the ladies.
Friday begins with a wine reception (sparkling grape juice for those under 21) with chick flicks afterwards in the lodge.
Saturday includes a continental breakfast, followed by a bus to downtown Traverse City to shop. Back at Timber Ridge for a buffet dinner followed by more movies and popcorn.
Sunday wraps up the weekend with a final continental breakfast.
No guys allowed for special weekend activities. Two night stay required.


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A new technology being used by the Marietta Police Department is offering residents a way to secretly mark and identify valuable property.
Police unveiled the new partnership with CopDots on Friday. CopDots allows users to imprint a microscopic serial code on everything from jewelry to clothing to electronics.
They say those numbers will then be entered into a nationwide database to allow authorities to track back stolen items to the proper owners.
Police demonstrated the technology during a press conference on Friday morning.
They say several jurisdictions already are part of the CopDot program.
For more information on CopDots visit their website at copdots.com.
35 Skyline DriveLake Mary, FL 32746
Phone: (407) 644-3535News Tips: (866) 55-FOX35


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"The NoA outlines the building blocks of each grantee's award"
Notice of Award Document
Though each grantee gets a Notice of Award (NoA) document when it first receives an award, the document is an essential resource for the whole span of the project period. A NoA outlines the basic elements of the Federal funding provided to the grantee. Information on the grant, project budget, project period, and grantee organization is fundamental for a grantee's future reporting and recordkeeping.
The NoA is a technical document used for a range of Federal grant programs. The section summaries below explain the contents of the NoA specific to AFI grants. This sample NoA shows where the information appears on the document.
Box 1 – Awarding Office. Office of Community Services (OCS).
* 'Discretionary' is the Federal Government's term for competitive grant awards
Box 2 – Assistance Type. "Discretionary Grant."
Box 3 – Award Number. The number is in the format 90EIXXXX/01.
Box 4 – Amend. No. This will be blank on the NoA for the grant award. The box will include a number if the grant is changed during the project period.
* 'Demonstration' means the Government is evaluating the effectiveness of the grant program
Box 5 – Type of Award. "Demonstration."
Box 6 – Type of Action. This will be "New" for the initial NoA created for a grant award. It will be "Amendment" if the award is changed during the project period and a new NoA is issued to reflect the change.
Box 7 – Award Authority. P.L. 105-285; 42 U.S.C. 604 (this is the citation to the law authorizing HHS to award the grant.)
Box 8 – Budget Period. The 5-year period starting the date the award is issued and ending the date it expires.
Box 9 – Project Period. Like the budget period, this is the 5-year period starting the date the award is issued and ending the date it expires.
Box 10 – Cat. No 93.602 (Catalogue of Federal Domestic Assistance).
Box 11 – Recipient Organization and Authorized Official. The name and address of the grantee organization, and name of the official of the organization who signed the grant application.
Box 12 – Project/Program Title. The name of the AFI project as provided in the grant application.
Box 13 – County. The county where the grantee organization is located.
Box 14 – Congr. Dist. The congressional district where the grantee organization is located.
Box 15 – Principal Investigator or Program Director. This is the name of the official listed as the program director in the grant application. If the application did not provide a name, this box will be blank.
Box 16 – Approved Budget. This will list the entire Federal AFI grant amount as "Other" and as "Direct Costs." All other categories will be listed as zero. The amount of the Federal AFI grant will be listed as "Total Approved Budget."
Box 17 – Award Computation. This will display the amount of the Federal AFI grant as the "Federal Share" and the amount of required non-Federal cash contribution as the "Non-Federal Share." It will list the non-Federal share as equal to the Federal AFI grant amount.
Box 18 – Federal Share Computation. This will list the Federal AFI grant amount as the "Total Federal Share" and the "Fed. Share Awarded This Budget Period." It will list as zero the "Unobligated Balance Federal Share."
Box 19 – Amount Awarded This Action. This is the total amount of the AFI grant awarded for the 5-year period.
Box 20 – Federal $ Awarded This Project Period. This is the total amount of the AFI grant awarded for the 5-year period.
Box 21 – Authorized Treatment of Program Income. This will be "additional costs." This means grantees may use program income to pay program expenses.
Box 22 – Recipient Organization's Employer Identification Number.
Box 23 – Payee EIN. This is the EIN of the entity that will receive the grant funds. Boxes 22 and 23 usually list the grantee organization's EIN.
Box 24 – Object Class. An HHS accounting field.
Box 25 – Financial Information. Lists seven HHS accounting fields.
Box 26 – Remarks. Includes important information about the grant, such as the minimum and maximum amounts of the Federal grant funds that may be used for particular purposes.
Box 27 – Signature of ACF Grants Officer. The ACF official responsible for managing the fiscal aspects of the award.
Box 28 – Signature(s) Certifying Fund Availability. OCS Budget Officer.
Box 29 – Signature and Title – Program Officials. OCS Director or a representative of the Director.


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Compare Products: Check up to four products with to see a side-by-side comparison
Item #: 271TP100
Item #: 8883853BK
Item #: 8883850
Item #: 211295
Item #: 211304
Keep your café, coffee shop or restaurant as neat and sanitary as possible with our variety of toothpick dispensers. Your customers will thank you for keeping everything so easily accessible!
Other Beverage Equipment
- Commercial Coffee Makers / Brewers, Automatic
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- Water Filter Kits and Cartridges for Cold Beverage Equipment
- Water Appliance Connectors
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- Heat Exchanger Systems for Cold-Plate Drink Dispensers
- Outdoor Kegerator, Beer Dispenser, and Jockey Box Parts and Accessories
- Refrigerated Beverage Dispensers and Accessories


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Cholecystitis is an inflammation of the gallbladder wall and nearby abdominal lining. Cholecystitis is usually caused by a gallstone in the cystic duct, the duct that connects the gallbladder to the hepatic duct. Other causes of cholecystitis may include the following:
Bacterial infection in the bile duct system. The bile duct system is the drainage system that carries bile from the liver and gallbladder into the area of the small intestine called the duodenum.
Tumor of the pancreas or liver.
Decreased blood supply to the gallbladder. This can sometimes occur in persons with diabetes.
Gallbladder "sludge." This "sludge" is a thick material that cannot be absorbed by bile in the gallbladder and most commonly occurs in pregnant women or individuals who have experienced a rapid weight loss.
Cholecystitis can occur suddenly or gradually over many years.
A typical attack of cholecystitis usually lasts two to three days. However, each individual may experience symptoms differently. Symptoms may include:
Intense and sudden pain in the upper right part of the abdomen
Recurrent painful attacks for several hours after meals
Pain (often worse with deep breaths and extends to lower part of right shoulder blade)
Rigid abdominal muscles on right side
Slight fever
Jaundice. A yellowing of the skin and eyes.
Itching (rare)
Loose, light-colored bowel movements
Abdominal bloating
The symptoms of cholecystitis may resemble other medical conditions or problems. Always consult your doctor for a diagnosis.
In addition to a complete medical history and medical examination, diagnostic procedures for cholecystitis may include the following:
Ultrasound (also called sonography). A diagnostic imaging technique that uses high-frequency sound waves to create an image of the internal organs. Ultrasounds are used to view internal organs of the abdomen, such as the liver, spleen, and kidneys, and to assess blood flow through various vessels.
Hepatobiliary scintigraphy. An imaging technique of the liver, bile ducts, gallbladder, and upper part of the small intestine.
Cholangiography. X-ray examination of the bile ducts using an intravenous (IV) dye (contrast).
Cholescintigraphy (also called HIDA scan). A small amount of nonharmful radioactive material is injected simulating the gallbladder to contract. This test diagnoses abnormal contraction of the gallbladder or obstruction of the bile ducts.
Percutaneous transhepatic cholangiography (PTC). A needle is introduced through the skin and into the liver where the dye (contrast) is deposited and the bile duct structures can be viewed by X-ray.
Endoscopic retrograde cholangiopancreatography (ERCP). A procedure that allows the doctor to diagnose and treat problems in the liver, gallbladder, bile ducts, and pancreas. The procedure combines X-ray and the use of an endoscope, which is a long, flexible, lighted tube. The scope is guided through the patient's mouth and throat, then through the esophagus, stomach, and duodenum. The doctor can examine the inside of these organs and detect any abnormalities. A tube is then passed through the scope, and a dye is injected which will allow the internal organs to appear on an X-ray.
Computed tomography scan (CT or CAT scan). A diagnostic imaging procedure using a combination of X-rays and computer technology to produce horizontal, or axial, images (often called slices) of the body. A CT scan shows detailed images of any part of the body, including the bones, muscles, fat, and organs. CT scans are more detailed than general X-rays.
Specific treatment for cholecystitis will be determined by your doctor based on:
Your age, overall health, and medical history
Extent of the disease
Your tolerance of specific medicines, procedures, or therapies
Expectations for the course of the disease
Your opinion or preference
Treatment for acute cholecystitis usually involves a hospital stay to reduce stimulation to the gallbladder. Antibiotics are usually administered to fight the infection. Fluids are given intravenously and the stomach is kept empty until symptoms resolve. Sometimes, the gallbladder is surgically removed, either immediately or later after the episode of acute cholecystitis has resolved.
Other treatment options may include:
Oral dissolution therapy. Drugs made from bile acid are used to dissolve the stones
Medications. These are used to prevent the formation of gallstones.
Low-fat diet
Pain management
The overall prognosis for cholecystitis is favorable. In some individuals, complications may arise if other organs are involved. Gallstones can return in the bile duct system after surgical removal of the gallbladder.
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Phoebe Putney Health System is a network of hospitals, family medicine clinics, rehab facilities, auxiliary services, and medical education training facilities. Founded in 1911,
Phoebe Putney Memorial Hospital (the flagship hospital) is one of Georgia's largest comprehensive regional medical centers. From the beginning, Phoebe's mission and vision
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