text: content LE Magazine October 2006 Nutritional Therapies for Managing HomocysteineBy William Davis, MD "Inadequate blood folate is common among those who do not take multivitamin supplements but unusual among those who do." —Godfrey P. Oakley, MD US Centers for Disease Control and Prevention Ways to Lower Homocysteine Naturally The potential benefits of nutritional homocysteine control are great, while the dangers are virtually nonexistent. Based on the weight of accumulated evidence, our clinic advocates lowering homocysteine levels above 7-8 µmol/L using a graded dosing of three B vitamins, up to maximum doses of 5000 mcg of folic acid, 100 mg (occasionally even 500 mg under a doctor's supervision) of vitamin B6, and up to 1000 mcg of vitamin B12. Our treatment goal is to lower homocysteine to below 7 µmol/L. We also advocate using choline and trimethylglycine (TMG or betaine) from food or nutritional supplements to augment the benefits of B vitamins and to more effectively suppress the after-meal surge in homocysteine that is not fully controlled by vitamins alone. Your choices for controlling homocysteine include: • Folic acid. Folic acid is the most important factor in controlling homocysteine. Although the US recommended daily allowance (RDA) for adults is only 400 mcg,47 extensive survey data showed that an extraordinary 88% of US adults have a folic acid intake below the RDA.48 Low folic acid intake by pregnant women carries a particularly dire risk, causing devastating neural tube defects in newborns. Low folic acid intake from diet is a growing problem because of food processing. This prompted the FDA to mandate folic acid fortification in enriched grain products. Fortification provides an estimated extra 100 mcg of folic acid daily for most adults and does indeed result in modest reductions of about 0.5 µmol/L in homocysteine. Nonetheless, obtaining sufficient quantities of folate (the food form of folic acid) from foods is difficult, and the majority of Americans not taking folic acid supplements have sufficiently low blood levels that allow higher homocysteine levels.49 Keep in mind that folic acid supplements are twice as bioavailable as folate from food.50 For example, 200 mcg of a folic acid supplement (as an individual supplement or added to grains) provides the same active quantity as 400 mcg of naturally occurring folate from food.51 If you do not eat grain products or you have a higher level of homocysteine, specific folic acid supplementation beyond that in your diet will be necessary. A daily folic acid dose of 800 mcg may lower homocysteine by around 25%.52-53 However, some doctors prescribe folic acid doses up to 5000 mcg for highly elevated homocysteine levels. • Vitamin B12. Vitamin B12 deficiency is common and can contribute to rising homocysteine, particularly in people over 65. In rare cases, replacing folic acid alone can mask a latent B12 deficiency, resulting in nervous system disorders. As a general rule, vitamin B12 and folic acid should be replaced together to maximize their homocysteine-lowering effects. Absorption of B12 is a little tricky, and in the past, physicians simply injected B12. However, more recent data suggest that a dose of 500-2000 mcg is every bit as good as an injection.54 A recent dose-exploring trial established that even 500 mcg of B12 achieves the same effect in correcting B12 deficiency as injectable forms. If you are not B12 deficient (discuss this with your doctor), then lesser doses are sufficient. Our clinic commonly advises patients to take 250 mcg of B12 along with folic acid, a dose that provides about two thirds of the effectiveness of the higher doses.54 • Vitamin B6. Taken along with folic acid, vitamin B6 is effective in blocking post-meal surges of homocysteine, particularly when methio-nine-rich meats are part of the meal. Low blood levels of B6 are common, especially in people with higher homocysteine levels.55 The precise dose of B6 required for maximum homocysteine lowering has been controversial, with doses of 2–50 mg commonly used in clinical studies. However, Dutch researchers who have extensive experience with homocysteine-lowering therapies routinely use 250 mg of B6 without ill effect.43,56,57 High-dose vitamin B6 (100-500 mg per day) has been used successfully in managing perimenstrual symptoms and carpal tunnel syndrome.58 However, in rare cases, higher doses may cause nervous system dysfunction (peripheral neuropathy).58 Most reported cases of neuropathy associated with vitamin B6 supplementation involved intake of 500 mg or more daily for two years or more.59 Vitamin B6 doses higher than 100 mg should therefore be used only under medical supervision. The vast majority of people obtain substantial homocysteine-lowering effects with 50-100 mg per day, provided folic acid is at optimal levels. • Trimethylglycine (TMG). Also commonly known as betaine, TMG is a constituent of food. The average American ingests 500–2000 mg of TMG a day. Supplemental TMG reduces homocysteine starting at a dose of 1000 mg a day, up to a maximum 20% reduction at 6000 mg per day, the dose often used in severe homocysteine disorders.60 TMG is the most effective nutritional agent for suppressing the after-meal surge in homocysteine, slashing levels up to 50%.60-62 We commonly use 2000 mg per day as a starting dose for fasting homocysteine levels that do not fully respond to the three B vitamins, using higher doses for the after-meal surge seen with methionine loading. Spinach and wheat germ are two particularly rich food sources of TMG. Be aware that the 6000-mg dose of TMG has been found to raise LDL by around 10%,63 and LDL should therefore be monitored when using this high dose of TMG. • Choline. Choline is directly converted to TMG in the body. Choline is readily available in various foods and also as a nutritional supplement. Most people ingest 300-1000 mg a day from dietary sources. Choline has recently gained acceptance as an essential nutrient. To avoid deficiency states, the National Academy of Sciences and the US Institute of Medicine recommend a daily intake of 550 mg for men and 425 mg for women. Higher doses are required to obtain the full benefit of lowering homocysteine. Like TMG, choline has modest effects on fasting homocysteine and a larger effect on the after-meal surge of homocysteine.64 A common dose is 2000-4000 mg per day. • Avoiding methionine-rich foods. Methionine is an amino acid found in food, particularly red meats and dairy products. Although methionine is an essential amino acid, it is also suspected to cause atherosclerotic plaque growth, both directly as well as indirectly by increasing homocysteine levels.65 The US RDA for methionine is 900 mg a day, but the average American takes in a greater quantity of around 2000 mg a day.37 If excess methionine is available in the diet, more homocysteine is produced. This provides the basis for one of the tests for hidden homocysteine excess, the "methionine-loading" test. The after-meal surge in homocysteine is prevented by vitamin B6 availability, along with choline and TMG. • Fish oil. Along with its other remarkable benefits such as lowering triglycerides, reducing fibrinogen, and stabilizing abnormal heart rhythms, fish oil may lower homocysteine. Homocysteine reductions of 36-48% have been reported,66,67 though practical experience suggests a more modest drop of 1-2 µmol/L can be expected. • Taurine. This amino acid and byproduct of methionine meta-bolism is emerging as a promising agent for reducing the dangers of homocysteine.68 However, further human data are needed to assess its effects. • Exercise. In a cardiac rehabilitation program following bypass surgery, angioplasty, or heart attack, 76 participants experienced a modest 12% reduction in homocysteine just by engaging in a modest program of regular exercise. How or why exercise results in such a reduction is unclear, but this is yet another example of how physical activity yields broad health-promoting benefits.69 Foods Naturally Rich In Folate The US government's mandate to supplement grain products with folic acid means that, in a practical sense, most folic acid-enriched foods (such as white bread, crackers, and breakfast cereals) are highly processed. Substantial quantities of naturally occurring folate are found in several select foods listed below. Spinach, black beans, and wheat germ are the superstars in folic acid content. While it is difficult to obtain sufficient folic acid every day through diet alone, these foods (along with folic acid supplements) can you help meet your requirements. Keep in mind that the amount of folic acid taken as a supplement is equal to nearly double the amount of food folate. For example, 400 mcg of folate from broccoli yields the same as 200 mcg of a folic acid supplement.50,58 To avoid confusion, in our list we have converted all units to equivalent quantities of folic acid. It is important to recognize that cooking, canning, and exposing foods for prolonged periods (for example, uncovered in the refrigerator) all sharply diminish the folate content of foods. Recall that the RDA for folic acid is 400 mcg per day. Combining foods rich in folic acid with supplemental folic acid can help you exceed this rock-bottom minimum. Folic acid content (mcg) Avocado: 1 cup, sliced 81 Black beans: 1/2 cup, cooked 128 Broccoli: 1 cup, chopped 55 English walnuts: 1/2 cup, chopped 57 Hazelnuts and filberts: 1/2 cup, whole 65 Orange juice: 6 oz. 54 Romaine lettuce: 1 cup, shredded 64 Spinach: 1 cup, cooked 263 Sunflower seeds: 1/4 cup, raw 82 Wheat germ: 4 tbsp. 128 Homocysteine, Mood, and Memory Homocysteine plays an important role in depression. Poor response to antidepressant medication, dysthymia (a lesser form of depression), and full-fledged depression have all been linked to low folic acid levels, which are often accompanied by high homocysteine levels.71 Other studies suggest that higher homocysteine levels are very prevalent among the depressed, with up to 50% of subjects exhibiting homocysteine levels above 10 µmol/L.72,73 Antidepressant medications may have limited effectiveness in treating depression, which may, however, respond to folic acid. Studies have firmly established that folic acid replacement, resulting in reduced homocysteine blood levels, is an important treatment for depression. In an Italian study, folic acid supplementation yielded improvements in mood similar to those produced by the use of conventional antidepressants.74 Moreover, several studies have shown that response to prescription antidepressants like fluoxetine (Prozac®) is substantially improved by taking as little as 500 mcg of folic acid per day.75,76 Although few psychiatrists have added folic acid to their antidepressant treatment protocols, the data suggest that this simple, inexpensive treatment should be a part of every depressed person's panel of therapies. Doses of 1000-5000 mcg are most effective, generally along with 25-100 mg of vitamin B6 and 100-500 mcg of vitamin B12. There is a growing appreciation of the role of folic acid, vitamins B6 and B12, and homocysteine in the cognitive decline associated with aging. It is well established that diminished memory and cognitive function are associated with deficiencies of these B vitamins and higher homocysteine levels.77,78 An MRI study showed that lower folic acid blood levels were associated with markers of neuropathology in the portion of the brain responsible for higher mental function.79 Last year, Italian researchers reported on the relationship between homocysteine, dementia, and Alzheimer's disease. For four years, the investigators followed a group of 816 dementia-free adults, averaging 74 years of age. During this interval, 112 subjects developed dementia, including 70 who were diagnosed with Alzheimer's disease. Individuals who had baseline homocysteine values of greater than 15 µmol/L had a twofold greater risk of developing dementia, and their risk of developing Alzheimer's disease was more than two times higher than in subjects with lower homocysteine values. The scientists concluded that elevated homocysteine is an independent risk factor for developing dementia and Alzheimer's disease.80 Homocysteine, Bone Density, and Osteoporosis Homocysteine may play a role in bone density and the risk of osteoporotic fractures, according to emerging findings.81-83 Researchers examined the association between homocysteine concentration and the risk of hip fracture in over 2,000 men and women, aged 59-81, enrolled in the Framingham Study.81 Blood samples from the participants were collected between 1979 and 1982, and were analyzed for homocysteine concentration. The participants were followed through June 1998 for incident hip fracture. Men and women in the highest quartiles of homocysteine concentration experienced a greater risk of hip fracture than those in the lowest quartile—the risk was almost four times higher for men and nearly two times greater for women. The investigators concluded that homocysteine concentration, which can easily be modified with nutritional intervention, is an important risk factor for hip fracture in middle-aged and elderly adults.81 Foods Rich In Choline And Trimethylglycine (Betaine) Choline and trimethylglycine (TMG) both reduce homocysteine, particularly the surge of homocysteine that occurs after a methionine-rich meal (of meat, for example). Maximum lowering of homocysteine occurs when choline and trimethylglycine are combined with folate-rich foods or folic acid supplements. Below is a list of foods rich in choline or TMG. We confine our list to healthy foods that are rich in these two nutrients and exclude choline- or TMG-rich foods (such as sausage) that are clearly unhealthy for other reasons. To avoid liver disease from choline deficiency, the US Institute of Medicine recommends a daily choline intake of 550 mg for men and 425 mg for women. The precise dose of choline for lowering homocysteine is not well known, but our clinic has had success with 2000-4000 mg a day. TMG lowers homocysteine starting at a dose of 1000 mg a day, with full effect at 6000 mg per day. As noted previously, high-dose TMG intake may elevate LDL levels, which should be monitored with your doctor's help.63 Choline (mg) Trimethylglycine (mg) Almonds: 1/2 cup 37 Atlantic cod: 4 oz. filet 95 10 Baked beans: 1 cup, canned 80 Beets: 1 cup, canned and drained 10 466 Broccoli: 2 spears 30 Brussels sprouts: 1 cup, cooked 64 Cauliflower: 1 cup, cooked 48 Chicken: 4 oz. roasted, w/o skin 34 Green peas: 1 cup 44 Hazelnuts or filberts: 1/2 cup 31 Milk: skim, 1 cup 38 4 Oat bran: 1/2 cup, raw 28 15 Orange roughy: 4 oz., cooked 41 Salmon: 4 oz., cooked 74 Spinach: 1 cup, raw 7 180 Spinach: 1 cup, cooked 45 1,161 Sweet potato: 1 medium 15 39 Tilapia: 4 oz. 94 29 Tofu: 1 cup, soft 69 Tomatoes: 1 cup, chopped 12 55 Tomato sauce: 8 oz. 50 Wheat bran: 1/2 cup 37 670 Wheat germ, toasted: 4 tbsp. 38 310 Whole wheat bread: 2 slices 13 101 Adapted from the USDA Database for the Choline Content of Common Foods, 2004, and Zeisel et al.70 Another study confirmed the relationship between elevated homo-cysteine levels and osteoporotic fractures in older adults. Dutch researchers followed over 2,000 men and women over the age of 55 for five to eight years.82 They determined that an increased level of homocysteine was a strong risk factor for osteoporotic fracture in both men and women. Their research suggests that the risk posed by elevated homocysteine is independent of other factors such as bone mineral density.82 Subsequent research, however, suggests a relationship between homocysteine and bone density. Researchers from Tufts University investigated the relationship between homocysteine, measures of folate and vitamin B12, and bone mineral density in adults aged 55 and older.83 They found that individuals with serum homocysteine levels equal to or above 20 µmol/L had significantly lower bone mineral density than subjects with homocysteine levels below 10 µmol/L, as determined by DEXA hip scans. The investigators also found a relationship between bone density and methylmalonic acid, which is a measure of tissue vitamin B12 status. Elevated levels of methylmalonic acid, indicating low tissue levels of vitamin B12, were associated with decreased bone mineral density and an increased prevalence of osteoporosis. The researchers concluded that elevated homocysteine and decreased vitamin B12 status were associated with decreased bone mineral density in older adults. In this study, serum and red blood cell folate levels were not related to bone mineral density or osteoporosis.83 In another recent study, the combination of vitamin B12 and folate helped decrease homocysteine levels and prevent hip fractures in individuals who had previously suffered a stroke.84 Elevated homocysteine is a risk factor for both ischemic stroke and osteoporotic fracture in men and women. Over 500 male and female stroke survivors suffering from residual partial paralysis were supplemented with 5000 mcg of folate and 1500 mcg of vitamin B12 or placebo for two years. At baseline, all the patients had high levels of homocysteine and low serum levels of vitamin B12 and folate. At the two-year follow-up, homocysteine levels increased 31% in the placebo group and fell 38% in the B12-folate group. The B12-folate group also experienced a decreased rate of hip fracture compared to the placebo group. The researchers concluded that supplementing with vitamin B12 and folate is safe and effective in reducing hip fracture risk in elderly patients following a stroke.84 Managing elevated homocysteine may thus be an important strategy for preserving bone mineral density, minimizing osteoporosis risk, and preventing bone fractures.81-84 While numerous nutritional remedies may be helpful for reducing homocysteine levels, vitamin B12 may play an especially important role in promoting healthy bone mineral density,83 and the combination of B12 and folate may reduce hip fracture risk following a stroke.84 The mechanism by which homocysteine affects bone density and fracture risk remains unknown, but some investigators speculate that high serum homocysteine concentration may weaken bone by interfering with collagen cross-linking, thus increasing the risk of osteoporotic fracture.81 Emerging research relates deficient folate and high homocysteine levels with such disparate conditions as complications of pregnancy, inflammatory bowel disease, and some cancers.85-87 Although we await data demonstrating just how supplementation benefits these conditions, the ease of nutritional intervention argues for simply correcting elevated levels of homocysteine, drawing on the compelling knowledge base already established. Conclusion Homocysteine is an amino acid that, even at levels previously regarded as normal, exaggerates the adverse effects of other atherosclerotic risk factors and may heighten long-term risk for heart attack, stroke, osteoporosis, depression, blood clot formation, and even cancer. Fortunately, the nutritional management of elevated homocysteine levels is a relatively straightforward proposition. Despite the government's well-intended mandate to add folic acid to grain products, most of us are still marginally and sometimes substantially deficient of folic acid. Folic acid supplementation, along with other nutritional strategies to lower homocysteine—using vitamins B6 and B12, choline, and trimethylglycine (TMG)—can provide powerful protection against homocysteine's ill effects on your life and health. Dr. William Davis is an author, lecturer, and cardiologist practicing in Milwaukee, WI. He is founder of Track Your Plaque, a heart disease- prevention program that shows how to use the CT scans to control coronary plaque. He can be contacted through www.trackyourplaque.com. References 1. Stampfer MJ, Malinow MR, Willett WC, et al. A prospective study of plasma homocyst(e)ine and risk of myocardial infarction in US physicians. JAMA. 1992 Aug 19;268(7):877-81. 2. Stanger O, Herrmann W, Pietrzik K, et al. Clinical use and rational management of homocysteine, folic acid, and B vitamins in cardiovascular and thrombotic diseases. Z Kardiol. 2004 Jun;93(6):439-53. 3. Nygard O, Nordrehaug JE, Refsum H, et al. Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med. 1997 Jul 24;337(4):230-6. 4. Tyagi SC. Homocysteine redox receptor and regulation of extracellular matrix components in vascular cells. Am J Physiol. 1998 Feb;274(2 Pt 1):C396-C405. 5. Taha S, Azzi A, Ozer NK. Homocysteine induces DNA synthesis and proliferation of vascular smooth muscle cells by a hydrogen peroxide-independent mechanism. Antioxid Redox Signal. 1999;1(3):365-9. 6. Kartal ON, Negis Y, Aytan N. Molecular mechanisms of cholesterol or homocysteine effect in the development of atherosclerosis: Role of vitamin E. Biofactors. 2003;19(1-2):63-70. 7. Zeng XK, Guan YF, Remick DG, Wang X. Signal pathways underlying homocysteine-induced production of MCP-1 and IL-8 in cultured human whole blood. Acta Pharmacol Sin. 2005 Jan;26(1):85-91. 8. Zeng XK, Remick DG, Wang X. Homocysteine induces production of monocyte chemoattractant protein-1 and interleukin-8 in cultured human whole blood. Acta Pharmacol Sin. 2004 Nov;25(11):1419-25. 9. Auer J, Berent R, Lassnig E, Eber B. C-reactive protein and coronary artery disease. Jpn Heart J. 2002 Nov;43(6):607-19. 10. Higuchi M, Castelli JB, Aiello VD, et al. Great amount of C.pneumoniae in ruptured plaque vessel segments at autopsy. A comparative study with stable plaques. Arq Bras Cardiol. 2000 Feb;74(2):149-51. 11. Sacks FM, Moye LA, Davis BR, et al. Relationship between plasma LDL concentrations during treatment with pravastatin and recurrent coronary events in the Cholesterol and Recurrent Events trial. Circulation. 1998 Apr 21;97(15):1446-52. 12. Rubins HB, Robins SJ, Collins D, et al. Distribution of lipids in 8,500 men with coronary artery disease. Department of Veterans Affairs HDL Intervention Trial Study Group. Am J Cardiol. 1995 Jun 15;75(17):1196-201. 13. Voutilainen S, Morrow JD, Roberts LJ, et al. Enhanced in vivo lipid peroxidation at elevated plasma total homocysteine levels. Arterioscler Thromb Vasc Biol. 1999 May;19(5):1263-6. 14. Sainani GS and Sainani R. Homocysteine and its role in the pathogenesis of atherosclerotic vascular disease. J Assoc Physicians India. 2002 May;50 Suppl16-23. 15. Laaksonen R, Janatuinen T, Vesalainen R, et al. High oxidized LDL and elevated plasma homocysteine contribute to the early reduction of myocardial flow reserve in healthy adults. Eur J Clin Invest. 2002 Nov;32(11):795-802. 16. Shatrov VA, Brune B. Induced expression of manganese superoxide dismutase by non-toxic concentrations of oxidized low-density lipoprotein (oxLDL) protects against oxLDL-mediated cytotoxicity. Biochem J. 2003 Sep 1;374(Pt 2):505-11. 17. Scaramella JG. Hyperhomocysteinemia and left internal jugular vein thrombosis with Meniere's symptom complex. Ear Nose Throat J. 2003 Nov;82(11):856, 859-60, 65. 18. Sauls DL, Wolberg AS, Hoffman M. Elevated plasma homocysteine leads to alterations in fibrin clot structure and stability: implications for the mechanism of thrombosis in hyperhomocysteinemia. J Thromb Haemost. 2003 Feb;1(2):300-6. 19. Ebbesen LS, Christiansen K, Ingerslev J. Hyperhomocysteinemia due to folate deficiency is thrombogenic in rats. J Nutr. 2003 Jul;133(7):2250-5. 20. Al-Obaidi MK, Philippou H, Stubbs PJ, et al. Relationships between homocysteine, factor VIIa, and thrombin generation in acute coronary syndromes. Circulation. 2000 Feb 1;101(4):372-7. 21. Khajuria A, Houston DS. Induction of monocyte tissue factor expression by homocysteine: a possible mechanism for thrombosis. Blood. 2000 Aug 1;96(3):966-72. 22. Derbeneva SA, Pogozheva AV. Homocysteine as a coronary risk factor. Vopr Pitan. 2003;72(5):43-8. 23. Debreceni L. Homocysteine—a risk factor for atherosclerosis. Orv Hetil. 2001 Jul 8;142(27):1439-44. 24. Magott M. Homocysteine as a nonlipid factor in the pathogenesis of atherosclerosis. Postepy Hig Med Dosw. 1998;52(3):259-67. 25. Lentz SR, Sadler JE. Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. J Clin Invest. 1991 Dec;88(6):1906-14. 26. Hayashi T, Honda G, Suzuki K. An atherogenic stimulus homocysteine inhibits cofactor activity of thrombomodulin and enhances thrombomodulin expression in human umbilical vein endothelial cells. Blood. 1992 Jun 1;79(11):2930-6. 27. Tribouilloy CM, Peltier M, Iannetta Peltier MC, et al. Plasma homocysteine and severity of thoracic aortic atherosclerosis. Chest. 2000 Dec;118(6):1685-9. 28. Lentz SR, Rodionov RN, Dayal S. Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: the potential role of ADMA. Atheroscler Suppl. 2003 Dec;4(4):61-5. 29. Graham IM, Daly LE, Refsum HM, et al. Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. JAMA. 1997 Jun 11;277(22):1775-81. 30. Rasouli ML, Nasir K, Blumenthal RS, et al. Plasma homocysteine predicts progression of atherosclerosis. Atherosclerosis. 2005 Jul;181(1):159-65. 31. Mayer EL, Jacobsen DW, Robinson K. Homocysteine and coronary atherosclerosis. J Am Coll Cardiol. 1996 Mar 1;27(3):517-27. 32. Anon. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA. 2002 Oct 23;288(16):2015-22. 33. Refsum H, Ueland PM, Nygard O, Vollset SE. Homocysteine and cardiovascular disease. Annu Rev Med. 1998;49:31-62. 34. Selhub J, Jacques PF, Rosenberg IH, et al. Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations. Ann Intern Med. 1999 Sep 7;131(5):331-9. 35. Mann NJ, Li D, Sinclair AJ, et al. The effect of diet on plasma homocysteine concentrations in healthy male subjects. Eur J Clin Nutr. 1999 Nov;53(11):895-9. 36. Krajcovicova-Kudlackova M, Blazicek P, Kopcova J, Bederova A, Babinska K. Homocysteine levels in vegetarians versus omnivores. Ann Nutr Metab. 2000;44(3):135-8. 37. Chrysohoou C, Panagiotakos DB, Pitsavos C, et al. The associations between smoking, physical activity, dietary habits and plasma homocysteine levels in cardiovascular disease-free people: the "ATTICA" study. Vasc Med. 2004 May;9(2):117-23.3811. 38. Hoogeveen EK, Kostense PJ, Beks PJ, et al. Hyperhomocysteinemia is associated with an increased risk of cardiovascular disease, especially in non-insulin-dependent diabetes mellitus: a population-based study. Arterioscler Thromb Vasc Biol. 1998 Jan;18(1):133-8. 39. O'Callaghan P, Meleady R, Fitzgerald T, Graham I. Smoking and plasma homocysteine. Eur Heart J. 2002 Oct;23(20):1580-6. 40. Hopkins PN, Wu LL, Hunt SC, et al. Lipoprotein(a) interactions with lipid and nonlipid risk factors in early familial coronary artery disease. Arterioscler Thromb Vasc Biol. 1997 Nov;17(11):2783-92. 41. Hackam DG, Peterson JC, Spence JD. What level of plasma homocyst(e)ine should be treated? Effects of vitamin therapy on progression of carotid atherosclerosis in patients with homocyst(e)ine levels above and below 14 micromol/L. Am J Hypertens. 2000 Jan;13(1 Pt 1):105-10. 42. de Jong SC, Stehouwer CD, van den BM, et al. Normohomocysteinaemia and vitamin-treated hyperhomocysteinaemia are associated with similar risks of cardiovascular events in patients with premature peripheral arterial occlusive disease. A prospective cohort study. J Intern Med. 1999 Jul;246(1):87-96. 43. Vermeulen EG, Stehouwer CD, Twisk JW, et al. Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial. Lancet. 2000 Feb 12;355(9203):517-22. 44. Schnyder G, Roffi M, Flammer Y, Pin R, Hess OM. Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomized controlled trial. JAMA. 2002 Aug 28;288(8):973-9. 45. Liem AH, van Boven AJ, Veeger NJ et al. Efficacy of folic acid when added to statin therapy in patients with hypercholesterolemia following acute myocardial infarction: a randomised pilot trial. Int J Cardiol. 2004 Feb;93(2-3):175-9. 46. Toole JF, Malinow MR, Chambless LE, et al. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA. 2004 Feb 4;291(5):565-75. 47. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline (1998). US Dept. of Agriculture. 48. Subar AF, Block G, James LD. Folate intake and food sources in the US population. Am J Clin Nutr. 1989 Sep;50(3):508-16. 49. Tucker KL, Mahnken B, Wilson PW, Jacques P, Selhub J. Folic acid fortification of the food supply. Potential benefits and risks for the elderly population. JAMA. 1996 Dec 18;276(23):1879-85. 50. McNulty H, Pentieva K. Folate bioavailability. Proc Nutr Soc. 2004 Nov;63(4):529-36. 51. Oakley GP, Jr. Eat right and take a multivitamin. N Engl J Med. 1998 Apr 9;338(15):1060-1. 52. Durga J, van Tits LJ, Schouten EG, Kok FJ, Verhoef P. Effect of lowering of homocysteine levels on inflammatory markers: a randomized controlled trial. Arch Intern Med. 2005 Jun 27;165(12):1388-94. 53. Lewerin C, Matousek M, Steen G, et al. Significant correlations of plasma homocysteine and serum methylmalonic acid with movement and cognitive performance in elderly subjects but no improvement from short-term vitamin therapy: a placebo-controlled randomized study. Am J Clin Nutr. 2005 May;81(5):1155-62. 54. Eussen SJ, de Groot LC, Clarke R, et al. Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial. Arch Intern Med. 2005 May 23;165(10):1167-72. 55. Robinson K, Arheart K, Refsum H, et al. Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC Group. Circulation. 1998 Feb 10;97(5):437-43. 56. Vermeulen EG, Rauwerda JA, van den BM, et al. Homocysteine-lowering treatment with folic acid plus vitamin B6 lowers urinary albumin excretion but not plasma markers of endothelial function or C-reactive protein: further analysis of secondary end-points of a randomized clinical trial. Eur J Clin Invest. 2003 Mar;33(3):209-15. 57. Vermeulen EG, Stehouwer CD, Valk J, et al. Effect of homocysteine-lowering treatment with folic acid plus vitamin B on cerebrovascular atherosclerosis and white matter abnormalities as determined by MRA and MRI: a placebo-controlled, randomized trial. Eur J Clin Invest. 2004 Apr;34(4):256-61. 58. Bernstein AL. Vitamin B6 in clinical neurology. Ann NY Acad Sci. 1990;585:250-60. 59. Bendich A, Cohen M. Vitamin B6 safety issues. Ann NY Acad Sci. 1990;585:321-30. 60. Olthof MR, Verhoef P. Effects of betaine intake on plasma homocysteine concentrations and consequences for health. Curr Drug Metab. 2005 Feb;6(1):15-22. 61. Steenge GR, Verhoef P, Katan MB. Betaine supplementation lowers plasma homocysteine in healthy men and women. J Nutr. 2003 May;133(5):1291-5. 62. Holm PI, Ueland PM, Vollset SE, et al. Betaine and folate status as cooperative determinants of plasma homocysteine in humans. Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):379-85. 63. Olthof MR, Vliet TV, Verhoef P, Zock PL, Katan MB. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PLoS Med. 2005 May;2(5):e135. 64. da Costa KA, Gaffney CE, Fischer LM, Zeisel SH. Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load. Am J Clin Nutr. 2005 Feb;81(2):440-4. 65. Troen AM, Lutgens E, Smith DE, Rosenberg IH, Selhub J. The atherogenic effect of excess methionine intake. Proc Natl Acad Sci USA. 2003 Dec 9;100(25):15089-94. 66. Olszewski AJ, McCully KS. Fish oil decreases serum homocysteine in hyperlipemic men. Coron Artery Dis. 1993 Jan;4(1):53-60. 67. Moller JM, Nielsen GL, Ekelund S, Schmidt EB, Dyerberg J. Homocysteine in Greenland Inuits. Thromb Res. 1997 May 15;86(4):333-5. 68. Nonaka H, Tsujino T, Watari Y, Emoto N, Yokoyama M. Taurine prevents the decrease in expression and secretion of extracellular superoxide dismutase induced by homocysteine: amelioration of homocysteine-induced endoplasmic reticulum stress by taurine. Circulation. 2001 Sep 4;104(10):1165-70. 69. Ali A, Mehra MR, Lavie CJ, et al. Modulatory impact of cardiac rehabilitation on hyperhomocysteinemia in patients with coronary artery disease and "normal" lipid levels. Am J Cardiol. 1998 Dec 15;82(12):1543-5. 70. Zeisel SH, Mar MH, Howe JC, Holden JM. Concentrations of choline-containing compounds and betaine in common foods. J Nutr. 2003 May;133(5):1302-7. 71. Morris MS, Fava M, Jacques PF, Selhub J, Rosenberg IH. Depression and folate status in the US population. Psychother Psychosom. 2003 Mar;72(2):80-7. 72. Bottiglieri T, Laundy M, Crellin R, et al. Homocysteine, folate, methylation, and monoamine metabolism in depression. J Neurol Neurosurg Psychiatry. 2000 Aug;69(2):228-32. 73. Fava M, Borus JS, Alpert JE, et al. Folate, vitamin B12, and homocysteine in major depressive disorder. Am J Psychiatry. 1997 Mar;154(3):426-8. 74. Passeri M, Cucinotta D, Abate G, et al. Oral 5'-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study. Aging (Milano.). 1993 Feb;5(1):63-71. 75. Coppen A, Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J Affect Disord. 2000 Nov;60(2):121-30. 76. Godfrey PS, Toone BK, Carney MW, et al. Enhancement of recovery from psychiatric illness by methylfolate. Lancet. 1990 Aug 18;336(8712):392-5. 77. Kado DM, Karlamangla AS, Huang MH, et al. Homocysteine versus the vitamins folate, B6, and B12 as predictors of cognitive function and decline in older high-functioning adults: MacArthur Studies of Successful Aging. Am J Med. 2005 Feb;118(2):161-7. 78. Ellinson M, Thomas J, Patterson A. A critical evaluation of the relationship between serum vitamin B, folate and total homocysteine with cognitive impairment in the elderly. J Hum Nutr Diet. 2004 Aug;17(4):371-83. 79. Scott TM, Tucker KL, Bhadelia A, et al. Homocysteine and B vitamins relate to brain volume and white-matter changes in geriatric patients with psychiatric disorders. Am J Geriatr Psychiatry. 2004 Nov;12(6):631-8. 80. Ravaglia G, Forti P, Maioli F, et al. Homocysteine and folate as risk factors for dementia and Alzheimer disease. Am J Clin Nutr. 2005 Sep;82(3):636-43. 81. McLean RR, Jacques PF, Selhub J, et al. Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med. 2004 May 13;350(20):2042-9. 82. van Meurs JB, Dhonukshe-Rutten RA, Pluijm SM, et al. Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med. 2004 May 13;350(20):2033-41. 83. Morris MS, Jacques PF, Selhub J. Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans. Bone. 2005 Jun 8. 84. Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K. Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial. JAMA. 2005 Mar 2;293(9):1082-8. 85. Nakano E, Taylor CJ, Chada L, McGaw J, Powers HJ. Hyperhomocystinemia in children with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2003 Nov;37(5):586-90. 86. Gurbuz A, Karateke A, Mengulluoglu M. Elevated plasma homocysteine levels in preeclampsia and eclampsia. Int J Gynaecol Obstet. 2004 Nov;87(2):165-6. 87. Stover PJ. Physiology of folate and vitamin B12 in health and disease. Nutr Rev. 2004 Jun;62(6 Pt 2):S3-12. 88. Seddon JM, Gensler G, Klein ML. Evaluation of plasma homocysteine and risk of age-related macular degeneration. Am J Ophthalmol. 2006 Jan;141(1):201-3. 89. Available at: www.miami.com/mld/miamiherald/news/11942690.htm. Accessed June 21, 2005.


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BRUSSELS (Reuters) - Belgian pharmaceutical company Galapagos said on Monday it had discovered a possible drug to treat breast cancer and expected to start first clinical trials in humans within a year.
The company, which has a series of alliances for its pipeline of drug candidates, said in a statement that GLPG1790 had shown high activity against breast tumors that were 'triple-negative' - lacking oestrogen, progesterone or HER2 receptors.
Galapagos said the triple-negative breast cancer accounted for a fifth of breast cancers, usually affected young women, and lacked available targeted drugs.
(Reporting By Philip Blenkinsop)

subset: commoncrawl


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Skip Maine state header navigation
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|Home | Contact Us | News | Frequently Asked Questions
Drinking Water Safety
In an emergency, you will need water for drinking, food preparation and hygiene. Plan on having at least one gallon per person, per day on hand.
Never ration water. Drink the amount you need today, and try to find more for tomorrow. You can minimize the amount of water your body needs by reducing activity and staying cool.
Storing Water
Emergency Outdoor Water Sources
It's always better to obtain drinking water from a source that you know to be pure (public water supply, bottled water). However, if in an emergency you need to find water outside your home from one of these sources, be sure to purify the water before drinking it. It is important to tpurify any water of unknown quality. Water that looks clear can be contaminated.
Avoid water with floating material, an odor or dark color. Use saltwater only if you distill it first (see below). You should never drink flood water.
If you have a well that has been flooded the water should be tested and disinfected after the waters recede. Do not try to disinfect a well that is still under water. For a six inch wide well that is 300 feet deep, one gallon of household bleach is needed. If you think your well may be contaminated, contact the Maine Drinking Water Program 24 hours a day at 557-4214.
Three Ways to Purify Water
You must purify all water of uncertain purity before using it for drinking, food preparation or hygiene.
There are many ways to purify water. None is perfect. Often the best solution is a combination of methods. Before purifying:
Boiling is the safest method of purifying water.
Distillation will remove microbes not removed by boiling or disinfection, as well as heavy metals, salts and most other chemicals.
The water that drips from the lid into the cup is distilled.
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Isaac's Storm: A Man, a Time, and the Deadliest Hurricane in Historyby Erik Larson
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National Bestseller
September 8, 1900, began innocently in the seaside town of Galveston, Texas. Even Isaac Cline, resident meteorologist for the U.S. Weather Bureau failed to grasp the true meaning of the strange deep-sea swells and peculiar winds that greeted the city that morning. Mere hours later, Galveston found itself submerged in a monster hurricane that completely destroyed the town and killed over six thousand people in what remains the greatest natural disaster in American history--and Isaac Cline found himself the victim of a devestating personal tragedy.
Using Cline's own telegrams, letters, and reports, the testimony of scores of survivors, and our latest understanding of the science of hurricanes, Erik Larson builds a chronicle of one man's heroic struggle and fatal miscalculation in the face of a storm of unimaginable magnitude. Riveting, powerful, and unbearably suspenseful, Isaac's Storm is the story of what can happen when human arrogance meets the great uncontrollable force of nature.
From the Trade Paperback edition.
Riveting, powerful, and unbearably suspenseful, "Isaac's Storm" is the story of what can happen when human arrogance meets the great uncontrollable force of nature. Abridged. 5 CDs.
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Erik Larson lives in Seattle with his wife, three daughters, a Chinese fighting fish, a dwarf hamster, and a golden retriever named Molly.
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The Stark State College Foundation
Pathway to the Future
The Stark State Foundation is committed to providing resources to help Stark State College accomplish its mission of providing accessible, quality associate degree programs, training and lifelong education in a diverse and supportive learning environment.
The Stark State Foundation exists to bridge the gap between the needs and resources of Stark State College.
The non-profit, tax exempt corporation was established in 1986 to raise funds to provide assistance to Stark State students who would like to enhance their lives through education and training. The Foundation supports the college in areas that are not supported by taxes, tuition, or grants.
Stark State Foundation Board of Directors
As a 501(c) 3 organization, the Stark State Foundation is managed by board of directors comprised of business and community leaders. They oversee the Foundation's fund-raising and investment management to ensure that donors' interests are always met. In addition, they ensure they work closely with the College president and vice president for advancement and external relations to ensure that the College has the resources it needs to accomplish its mission and serve students. Members of the Foundation Board are listed here.
Our Students, Our Success, Our Spirit
As a community-based college of technology, Stark State changes lives in so many ways. We've created a climate that encourages personal and academic growth by offering a variety of programs to meet the needs of our changing world. However, as more and more students arrive on our doorstep, the need for support increases.
In reaching out to meet the varied needs of our student population, the Stark State Foundation encourages charitable giving by the private sector. Individuals, corporations, foundations and service organizations that choose to invest in the Foundation have a number of giving options:
- Provide funds for scholarships that can be named for a business, foundation or individual
- Establish a memorial – a gift in honor or in memory of a friend or loved one
- Donate special equipment to enhance student education in a particular degree program
- Naming Stark State as a beneficiary in a will, trust, insurance policy or annuity
Stark State is state-assisted rather than state-supported. Less than one-half of the operating budget is provided by state appropriations. State support is critically important, but it continues to decline as a percentage of the total operating budget.
Would you like to support Stark State students and the community?
Planned giving opportunities at Stark State
Stark State College needs and seeks the support of the community in order to continue helping students to achieve their educational goals and become productive members of our community. Stark State has been sustained by people like Don and Pauline Colaner, who feel a personal responsibility to support our efforts. Click here to read about how their special gifts have been an important impetus in bringing Stark State to its present strong position as a leader among two-year colleges.
Planned giving is one of a number of giving opportunities available. A planned gift provides donors with the immense personal satisfaction of making a substantial contribution toward the future of Stark State College, and provides financial and tax benefits. From the donor's financial perspectives and estate planning, a planned or "deferred" gift is often the right gift or the best gift to make. Planned giving provides a number of benefits and opportunities to:
- Perpetuate one's beliefs and values;
- Direct the disposition of one's assets for charitable purposes and avoid unnecessary taxes;
- Support the mission of the College in tangible and meaningful ways;
- Leave a legacy that will benefit the entire community, because of Stark State's vital role in community economic development.
There are a number of planned giving opportunities to consider, including:
- Bequests – Provide for Stark State College in your will.
- Major planned gifts – Give appreciated assets as part of a succession and/or estate plan. Paid-up life insurance policies, stocks and bonds may be gifted.
- Life-income gifts – Participate in a charitable trust agreement or other gift arrangement that can provide current income to you.
- Other gifts – Name the Stark State Foundation as beneficiary of Qualified Retirement Plans or IRAs or as beneficiary of a checking or savings plan.
Did you know you can support Stark State with a memorial gift?
If an obituary directs contributions to the charity of your choice, you can:
- Write a check for any amount payable to the Stark State Foundation.
- Let us know whom you wish to memorialize.
When we receive the check, we will:
- Send a thank you letter with tax deduction information.
- Notify the family that a gift was made by you in memory of the deceased.
All contributions to the Stark State Foundation go directly to support student needs.


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Woodworker's Journal
With that said, we are back to our regular brand of foolishness. We have real free plans, tool previews and the lot. I thank you for your indulgence and warn you that next April, we may not be able to contain ourselves again.
-- Rob Johnstone, editor: Woodworker's Journal


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This CD was recorded using a Blüthner piano chosen by Brahms in 1896 for a young British pianist, Margarita Hanson, who had met him while she was studying music in Germany. John Thwaites, the pianist here, enthuses in the booklet notes about its personality and musicality, and its ability to blend with strings. Blend, perhaps, but the recording here favours it to the extent that too often the strings sound small and distant, particularly when one of them is alone with the piano.
In the first movement of the Fauré, the strings seem to lurk at the back, while the quicksilver second movement sounds like a little piano concerto with a string accompaniment. Which is a shame, because there are lots of good things going on. The Adagio third movement recovers from a not-quite-unison opening to blossom into a beautiful silky elegy.
The strings hold their own better in the big-boned Brahms Quartet, with its assertive, passionate paragraphs. There is fine, lyrical playing in the Andante con moto third movement, with its long, undulating lines, and tremendous fire and energy in the Rondo alla Zingarese finale.
From the January 2012 issue. Subscribe to The Strad or download our digital edition as part of a 30-day free trial.
Kalina Macuta (violin) Daniel Blanch (piano)
David Garrett (violin) Royal Philharmonic Orchestra/Ion...
Ayako Yonetani (violin) Slovak State Philharmonic of...
Santiago Quartet, Ahmed Dickinson Cárdenas (guitar)


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Youth Select Life Vest from Onyx, Gray
Item # WX2-421815
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This item is shipped directly from the factory. To see the expected shipping date, please add to your Shopping Cart. Sorry, no express shipping available. We are unable to ship factory direct items to Alaska, Hawaii, Puerto Rico or APO or FPO addresses.
- Details & Specs
Youth Select Life Vest from Onyx®. A fully-loaded fisherman's favorite!
- Large mesh cargo pockets
- 2 zippered chest pockets
- Soft, comfortable flotation foam
- D-ring attachment... great for gloves and small accessories
- Reflective material on front and back for after-dark visibility
- Type III flotation device.
State Size, as available in Shopping Cart.Size Youth:
- Chest: 24-29"
- Weight: 50-90 lbs.
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Customer ReviewsNo reviews exist for this item....
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Windows And Your Home's Layout
We walked by a neighbor's apartment a few days ago and noticed an armoire leaning up against the bay windows, blocking the light. We thought that maybe their floor plan didn't quite allow them to use their space the way they wanted. We spotted this bookcase in the...
...Apartment Therapy LA group pool on Flickr and noticed it is placed perfectly under this bright window. While the furniture fits nicely in the space, sometimes your furniture may be larger or smaller then your home warrants. In this case, do you place the furniture (like the armoire) in front of the window? Let us know how you would handle this layout situation.
Check out more window ideas from Apartment Therapy:
- Look: Vines N' Roses Window Bars
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Image: Faith Emmaline
26 Comments
I don't think I could ever block a window--I need light and ventilation! On my block, there is a house where a bed frame and I think the edge of a bookcase or dresser is in front of a window. I would not want to have to climb on the bed to open and close the window.
Depends on how well I like the piece of furniture, how nice of a piece it is, and how long I plan to live in the apartment. I'm getting rid of a desk that doesn't fit my layout, but it's IKEA and particleboard the craigslist find I'm replacing it with is so much cuter.
My Cedar chest, on the other hand, is still in a kind of awkward position, but I would never, ever dream of getting rid of it, especially since I'm in grad school and probably won't be in this apartment more than 2 or 3 more years.
Those albums in the bookcase under the window are going to warp from heat and or cold. In answer to the question though, I wouldn't put an armoire in front of a window unless there were other windows in the room to compensate for the blocked light and air. I also would want the back of the piece to look interesting in some way. I vote for light over furniture.
I have walls of windows so it was not practical to not put any furniture in front of them -that said it did feel awkward at first. I just have have one piece directly against the windows - my desk armoire and it does have a finished back.
I don't think I'd ever cover a window with furniture, it takes away from the architectural features of the room and makes the space not feel right. And of course sunlight brings warmth into out interior spaces much more than artificial light ever can, I would never want to compromise that.
I don't think I'd ever block a window with an armoire. I try to keep my windows as open and accessible as possible. I'm not always successful, right now my couch sticks out about 5 inches in front of my patio door. It doesn't prevent me from using it, and most people probably don't even notice.
I would never block a window. The windows in what is supposed to be the living room are huge, and spans etnire walls. None of our living room furniture would fit there without blocking the windows, so we turned it into the bedroom. My friends make fun of me, but we love the arrangement, and most importantly, none of the windows are obfuscated.
In our living room the couch is in front of of a large window, pulled out about 6 in with long drapes behind it. There's no other wall in the livingroom to fit a couch, plus we don't open the drapes since they face the neighbors.
The new bedframe arriving this week (yaay!) will also be put in front of a window. Decided to get a king size bed even though room is only 11'x11'... husband and I don't mind the look of a large bed in a little space, the frame will cover some of the window but we are doing it so it looks purposeful rather than sloppy.
I would never block a window - EVER!!! When we were first married we rented a furnished home in a local seaside town. there was a huge dresser in front of the window. First thing we did was move it (and lift the orange carpet, but that's a whole nother story!). Hello, our house was right over the ocean where we could see whales playing all winter... The owners said we were mad and all the bright sunlight would drive us mad... Loved it, never shut the curtains either - lots of light and air and ocean and only whales to see in anyway!!!
Well, a nice easy chair or sofa in front of a window so that I can sit in the sunshine, sure.
Tell those neighbors who you are, and offer to rearrange their furniture for them. Then post the before & afters, here.
The only thing I'd block a window with is a bed with a high headboard. Anything else in any other room is trashy.
I envy all those people who live in large enough spaces that they can afford to leave a large section of wall furniture free. Windows are not "untouchable" in and of themselves, there is often a bigger picture (if not a bigger room).
In my bedroom I have a large chest of drawers that blocks the bottom 20cm (8 inches) of three-quarters of the only window. Although I have sheer net curtains it can just about be seen from outside. If I didn't have the chest of drawers there I would literally not be able to have it at all, as this is the only possible furniture arrangement in this room. Although I have sacrificed some of the window, and some daylight, overall the furniture balance of the room is optimum the way it is so it's more than worth it.
My desk sits in front of our living room's set of double windows - the top goes up for more storage (luckily no back to it) so it covers up part of one of them. But with the no back light still gets through.
Honestly, I try not to cover up windows with furniture - for the most part if it goes in front of the window, it's shorter than the ledge.
I try not to block windows but my bed covers up about a quarter of the window in my bedroom. It is a long, narrow room so there's no other arrangement that will work...unless I want to turn my bed 90 degrees and climb over it to crank open the window! I don't mind my arrangement though, it's nice waking up to a face full of sunshine. Well, except when a hangover's involved...
I wouldn't want to block a window unless I really had no ther choice. But, in our house we do have to be careful what we put in front of the window. Our dogs see neighbors or cars and jump up on whatever is there to see out the window! We have a couch there now and they are scratching it. We are working on finding something they won't harm or knock over!
I place furniture UNDER windows all the time, and occasionally it may cover the bottom couple inches of the window. But I'd never put furniture in FRONT of a window... that's just crazy! Notable exceptions made for those with walls of windows, that's understandable. ;o)
I also have walls of windows...I just try to keep the items low and unobtrusive. In my living room, I have a low west elm walton sectional in front of windows to the patio, and in my office I have a non-clunky desk.
Heck no! I saw that on an ep of something on HGTV and this had this big ugly china cabinet blocking the only window in their tacky dining room & a dresser in the bedroom! That is insane to me; I love natural light coming in the house. I might block an inch or so of a window with a shorter item, but that's it.
Block a window?! My little condo cave has one East facing Window and East facing door with glass in it. The west facing window is a basement window. I'm staved for light and could never block a window.
My boyfriend's parents have a giant entertainment center blocking one window in their living room, a tall hutch in front of the only window in the dining room, and refrigerator blocking the kitchen window. Seriously.
I do not like blocked windows. It especially bugs me when I go by an old building with big "window shopping" windows that have been boarded up add shelf space to a store. I couldn't imagine living or working in a place without windows.
No blocking here. It would cover up the retarded amount I am willing to spend on curtain fabric.
I agree blocking light is a bad thing, but we have our Ikea Expedit shelves in front of the window and it actually serves as a great spot. It keeps the room balanced, the light still comes through, and it serves the added purpose of filtering the view over the carpark opposite our apartment.
That window doesn't get much light so the records are fine (it's my window :)) I just made curtains for it based on a picture I probably saw on this blog.
I'm not a fan of blocking windows but I love when a piece of furniture fits well underneath one. It's built in day time lighting for your knickknacks. Plus the casement windows in our apartment are not so pretty so it's nice to draw the eye away from them a bit. My desk is also under a window. I love being able to look out the window while I'm working. The window ledge acts as storage for my pencils and paintbrushes.
We have a cable connection for our television that requires the television to sit in the bottom of one side of the window. I can't move it and to minimize the block, I have it on a LOW stand and off to the side. Sometimes life happens. Fortunately, we have two GIANT 72 inch windows in the room so light isn't really a problem and the sun doesn't rise or set on the side where the TV sits. They just didn't design houses in the 50's for modern conveniences!


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byScott Campbell on
We've Got It Covered
As part of CRN's 30th anniversary in 2012, we're taking a look back at some of the newsmakers we've talked to and written about. Here are five solution provider executives who have graced the cover of CRN magazine through the years and what they're doing now.
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Rapid progress in telecommunication and radar technology is placing increasing demands on wireless system performance. Such demands include high information capacity and the ability to track multiple mobile targets or users. 1–3 Military research programs in particular are placing heavy emphasis on Network Centric Warfare, a wireless network concept...


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Soundgarden frontman Chris Cornell's new song, Misery Chain - recorded with Joy Williams Music – will be released as part of the record Music From And Inspired By 12 Years A Slave, the new pre-Civil War film based on the true story of Solomon Northrup.
Northup (Chiwetel Ejiofor), a free black man from upstate New York, is abducted and sold into slavery. Facing cruelty (personified by a malevolent slave owner, portrayed by Michael Fassbender), as well as unexpected kindnesses, Solomon struggles not only to stay alive, but to retain his dignity. In the twelfth year of his unforgettable odyssey, Solomon's chance meeting with a Canadian abolitionist (Brad Pitt) will forever alter his life.
The soundtrack will be released digitally on November 5 before the CD is used on November 19 (it is available for Amazon pre-order); it was curated by 9-time Grammy Award winner John Legend and features a score by legendary film composer Hans Zimmer.
"12 Years a Slave" premiered at the Telluride Film Festival on August 30 before screening at the 2013 Toronto International Film Festival on September 5, the Philadelphia Film Festival on October 19, and New York Film Festival in October.
12 Years a Slave hit theaters on Rocktober 18 for a limited release with a nationwide release on November 1.
Cornell kicked off a fall North American tour comprised of intimate, acoustic shows on Rocktober 15 in San Diego, California.
Cornell is playing solo concerts under his Songbook format, performing tracks from throughout his career, while offering fans their first chance to hear acoustic arrangements of songs from 2012's King Animal, Soundgarden's first new studio record in over 16 years.


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Postthrombotic Syndrome
Postthrombotic syndrome (also called postphlebitic syndrome) is a complication of a blood clot that forms in a deep vein. Postthrombotic syndrome occurs because of damage to the vein caused by the blood clot (thrombosis).
Veins have valves that prevent blood from flowing the wrong way. These valves keep blood flowing toward the heart. Blood clots can damage the veins and valves, preventing blood from flowing back to the heart properly. As a result, blood collects in the area normally drained by the vein. The pressure from the buildup of blood causes small blood vessels (capillaries) to burst and bleed slightly.
The symptoms of postthrombotic syndrome include:
Postthrombotic syndrome can increase the risk for forming additional blood clots in the affected area. It can also occur in other areas with deep vein clots, such as in an arm.
Medicines called thrombolytics may be used to dissolve large blood clots and prevent postthrombotic syndrome. Specially fitted compression stockings may be used for prevention and treatment of postthrombotic syndrome.
eMedicineHealth Medical Reference from Healthwise
This information does not replace the advice of a doctor. Healthwise disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. How this information was developed to help you make better health decisions.
To learn more visit Healthwise.org
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What does AFAIK stand for?
What does AFAIK mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: AFAIK.
We've found a total of 2 definitions for AFAIK:
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What does AFAIK mean?
- as far as I know.
Still can't find the acronym definition you were looking for? Use our Power Search technology to look for more unique definitions from across the web!
"AFAIK." Abbreviations.com. STANDS4 LLC, 2014. Web. 2 Oct. 2014. <http://www.abbreviations.com/AFAIK>.


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Conduct information
The mission of the Office of Judicial Affairs is to maintain a campus community conducive to a positive learning environment. The judicial system is an educational tool to initiate student development, learning and responsibility. In support of the WKU Mission, The Office of Judicial Affairs strives to prepare students to be productive, engaged, and socially responsible citizen leaders of a global society.
The Office will address unacceptable behavior in a manner that informs students and guides them toward modified behavior. The Office will oversee that fairness and due process is met while administering the concepts outlined in the WKU Student Handbook.


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Harry O. Drake, 26, of Auburn was arrested on a felony warrant charging him with Receiving Stolen Property Second Degree.
According to Auburn police, a victim told officers that someone broke into their residence on the 300 block of N. Ross St. sometime between Dec. 19 and 26. The suspect(s) allegedly stole various electronic devices, firearms and coins valued at $4,600.
Drake developed as a suspect during investigation. Police located him, and discovered he was in possession of electronics and a firearm belonging to the victim. The value of the property recovered from Drake so far is $2,400.
Drake was transported to the Lee County Jail where his bond was set at $3,000.
The investigation is ongoing and additional charges are expected.
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January first may have already passed, but hundreds of people in Amarillo gathered Sunday to celebrate the start of another new year.
Saturday was the Vietnamese New Year Celebration. Operating on a 12 year cycle, this year marks the Year of the Snake. The Vietnamese community, Mayor Paul Harpole, veterans and others in our community came out to enjoy and respect the celebration which included the traditional Dragon Dance, singing and many other cultural performances.
"While the Lions are dancing inside they lit the firecrackers so once again drive away the evil spirits," said Kevin Liu, a sponsor for the event. "And so every little thing that we do goes back a long time and it has a lot of tradition with it."
Organizers say the celebration of the Vietnamese New Year is one of the biggest events in their culture every year.


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- The 2014 Big Picture on Cyber Security
- AFCEA Answers
- Ask the CIO
- Building the Hybrid Cloud
- CDWG/NetApp
- Connected Government: How to Build and Procure Network Services for the Future
- Continuing Diagnostics and Mitigation: Discussion of Progress and Next Steps
- Federal Executive Forum
- Federal Tech Talk
- The Future of Government Data Centers
- The Future of IT: How CIOs Can Enable the Service-Oriented Enterprise
- Government Perspectives on Mobility and the Cloud
- The Intersection: Where Technology Meets Transformation
- Maximizing ROI Through Data Center Consolidation
- Mitigating Insider Threats in Virtual & Cloud Environments
- Modern Mission Critical Series
- Moving to the Cloud. What's the best approach for me
- Navigating Tough Choices in Government Cloud Computing
- The New Generation of Database
- Reimagining the Next Generation of Government
- Satellite Communications: Acquiring SATCOM in Tight Times
- Targeting Advanced Threats: Proven Methods from Detection through Remediation
- Transformative Technology: Desktop Virtualization in Government
- The Truth About IT Opex and Software Defined Networking
- Value of Health IT
- Air Traffic Management Transformation Report
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Fridays, 10:00 a.m.
Inside Government is produced by the American Federation of Government Employees (AFGE). The program features interviews and commentary on a wide range of subjects that impact the lives and livelihoods of federal and D.C. government workers and the general public, and features lawmakers, journalists, union leaders, celebrities and more.
Rep. Hank Johnson discusses Social Security, dangers of sequestration on "Inside Government" - February 22, 2013
(From Left to Right) Hank Johnson, AFGE, Michael Meserve, Troy Tingey
Rep. Hank Johnson (D-Ga.)
Troy Tingey
President, AFGE Air Force Materiel Command Council 214
Michael Meserve
Western Region Vice President, AFGE Council of Prison Locals
Paul Ferris
President, AFGE William Beaumont Army Medical Center Local 2516
- Defending Social Security's solvency and long-term viability
- The importance of Social Security to middle class Americans
- The devastating impact sequestration would have on the U.S. economy
Troy Tingey
President, AFGE Air Force Materiel Command Council 214
- The impact furloughs would have on Air Force bases throughout the country
- The morale at AFGE locals in the Air Force Materiel Command Council
Michael Meserve
Western Region Vice President, AFGE Council of Prison Locals
- Working with congressional representatives to improve workplace conditions at the Bureau of Prisons
- Challenges of being a federal correctional officer
Paul Ferris
President, AFGE William Beaumont Army Medical Center Local 2516
- Legislative priorities for 2013
- Advocating for additional staff to care for the nation's veterans


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Product Details
Go Cowboys!
These 1 oz collegiate Silver rounds are guaranteed .999 fine and come to you in a capsule and small gift box, ideal for giving as a gift to a recent graduate, an athlete, alumni, or for any occasion. Due to overwhelming customer requests, APMEX is proud to present these collegiate 1 oz Silver rounds, which are sure to please and promise to sell out quickly.
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Silver -- why buy Silver from APMEX?Silver is one of the world's favorite bullion investments and is a popular way to diversify one's wealth. Call our Account Managers toll free at (800) 375-9006 or click on the "Live Chat" button. APMEX is where to buy Precious Metals! Also, you can come to us when it is time to sell Gold, Silver, Platinum, and Palladium.
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|Product ID:
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|Metal Content:
|1 troy oz
|Highland Mint
|2.9 mm
|39 mm
Reviewed by 1 customer
- Attractive Design
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Back at The Dunk Friday vs. Portland Pirates
Lowell, MA - The first place Providence Bruins fell to the Lowell Devils 3-2 Wednesday evening at the Tsongas Arena. The P-Bruins got their goals from Adam McQuaid and Jeremy Reich. The first place P-Bruins are back at home at the Dunkin' Donuts Center Friday, January 16 versus the Portland Pirates at 7:05 p.m. for Dunkin' Donuts Mug Night.
After a scoreless opening period, The Devils took a 1-0 lead at the 1:35 mark of the second period. Michael Swift tallied his sixth goal of the season, with Jon DiSalvatore and Vladimir Zharkov getting the assists. Providence tied the game at one, while on the power play at the 14:54 mark. Mikko Lehtonen held the puck halfway down the boards and passed it to Andrew Bodnarchuk at the blue line. He took a shot and the rebound went to McQuaid in the right face off circle who netted his third goal of the season. The game went into the second intermission tied at one.
In the third period, Providence took its first lead of the game at the 0:32 mark. Lehtonen dumped the puck into the zone and Wacey Rabbit pulled it out of the corner. Reich picked up the puck in the left face off circle and tallied his eleventh goal of the season. Lowell tied the game at two at the 5:53 mark. Swift grabbed his second goal of the game with Nicklas Bergfors and Anssi Salmela getting the assists. The Devils retook the lead at the 8:08 mark. Pierre-Luc Leblond scored his second goal of the season, while Matthew Corrente and Mark Fraser had the assists. Lowell went on to the 3-2 victory.
Tuukka Rask stopped 29 of 32 shots he faced for the P-Bruins, while Jeff Frazee made 29 saves for the Devils. The P-Bruins were 1-for-1 on the power play and 1-for-1 on the penalty kill.
The first place P-Bruins return home to The Dunk Friday against the Pirates at 7:05 p.m. for Dunkin' Donuts Mug Night. Providence is back on the road at the XL Center versus the Hartford Wolf Pack Saturday at 7:00 p.m. Providence finishes the weekend at The Dunk Sunday versus the Rochester Americans for LukOil Thunderstick Night at 4:05 p.m. Information on P-Bruins tickets can be obtained by calling the team ticket office at (401) 273-5000 or by logging onto the team website at providencebruins.com.


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Dust, pollen, pet dander and mold are common allergy triggers found in every home. Removing these from the air you breathe eliminates the source of your allergies. The best air purifiers for allergies and dust feature HEPA style filtration, which captures the greatest percentage of allergy-causing particles to purify and freshen the air you breathe. Alen offers the industry's first—and only—Allergy Relief Guarantee, which guarantees these select Alen Air Purifiers will reduce your allergy suffering within 60 days or your money back. We'll even pay return shipping! Create a refuge from allergies and dust inside your home and join other Alen customers who have experienced relief.
I have an Alen Paralda now for about 4 months. Our bedroom is up high in the house, almost like an attic. And we have a long-hair cat! I used to take albuterol and fluticasone on a daily basis to relieve asthma and allergy symptoms. Had been taking these for years. However, I have not had to use either one now for the last 3 months. This may be atypical, and it may not work the same for everyone. But I thought it was important to write a review, as this may help others. So for the last 3 months I also have slept a lot better. I cannot rave enough about the Paralda. Very quiet on setting 1, which is mostly what we use; have not had the need to go higher. Needless to say, I highly recommend this product.
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On March 17, 1997, at approximately 4:20 am, a customer stepped into the Plaid Pantry at 917 SW Gibbs St. near OHSU to find the clerk Jason Childers, a 27-year-old white male, deceased on the floor. It was determined that Mr. Childers died of multiple gunshot wounds while restocking the shelves of the Plaid Pantry.
Mr. Childers was described as a mild-mannered, good person with a slightly childish personality. He had no criminal record or contacts with the police. No cash was missing from the cash register and Childers' wallet was still present.
Detectives were able to determine that Mr. Childers was last seen alive by a customer buying a pack of cigarettes between 3:45 and 4:00 am.
If you have any information regarding the murder of Jason Childers you are encouraged to contact Crime Stoppers at 503-823-HELP (4357).
This case was featured on KPTV: http://www.kptv.com/story/23876467/cold-case-navy-veteran-gunned-down-while-working-at-plaid-pantry


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thank you for your answer .It was very helpful to me
My project is a knife that moving up an down and cuts a material to slices(many pages of paper).The step motor will move the material 1 to 3 mm foward so the knife cuts it . Every time the knife finishes one cut ,the motor will start to move .
I thote that this movemend was to fast for arduino to sense the knife but as you say ,it will be ok.
I will take it from start and rewrite my code


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Harford's greatest athletes [Pictures]
Harford County has produced some great athletes. Here are a few who were left off The Sun's list of Maryland's top 175 athletes but who merited inclusion, along with those who made it. Read about some of these athletes here.
July 27, 2012


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Occam's Razor is a scientific principle which states that among competing hypotheses, the simplest explanation is the best. This principle seems to hold true for cleaning your pots, pans, and dishes as well. Often times the simplest solution is the most effective!
These bamboo scrapers are simply one of the most useful tools around the house – for cleaning dishes, pots and pans, or whatever scraping needs one might find around the home or garden. For the price, you can't afford not to have these handy tools in hand. You'll soon wonder how you ever got along without them! Made from pure renewable bamboo, just toss 'em in the compost when they're finally worn out, and get out a new one!
Dimensions: 2.5" X 2"


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The CEO of General Motors joined first lady Michelle Obama to watch President Barack Obama deliver his State of the Union address. Mary Barra is the first female CEO of a major automaker. She took over the company this month and was invited to the Tuesday night address.President Obama acknowledged her in his speech while talking about the American dream: "I believe that here in America our success should depend not on accident of birth but the strength of our work ethic and the scope of our dreams. That's what drew our forebears here. That's how the daughter of a factory worker is CEO of America's largest auto maker; how the son of a barkeep is Speaker of the House; how the son of a single mom can be president of the greatest nation on Earth."The White House frequently invites guests to sit with the first lady to emphasize a policy or issue associated with the guest that the president wants to highlight.Andra Rush also was invited. She's a descendant of the Mohawk tribe from the Six-Nation Reservation and is founder and chair of the Rush Group. The family of companies includes Detroit Manufacturing Systems and the White House says it's one of the biggest Native American-owned businesses in the U.S.President Obama's remarks about her: "Two years ago, as the auto industry came roaring back, Andra Rush opened up a manufacturing firm in Detroit. She knew that Ford needed parts for the best-selling truck in America, and she knew how to make those parts. She just needed the workforce. So she dialed up what we call an American Job Center - places where folks can walk in to get the help or training they need to find a new job, or a better job. She was flooded with new workers. And today, Detroit Manufacturing Systems has more than 700 employees. What Andra and her employees experienced is how it should be for every employer - and every job seeker. So tonight, I've asked Vice President Biden to lead an across-the-board reform of America's training programs to make sure they have one mission: train Americans with the skills employers need, and match them to good jobs that need to be filled right now."VIDEO: Click on the video player above to watch the excerpts from the State of the Union address-The Associated Press contributed to this report
WJBK-TV | Fox 2 16550 West Nine Mile Rd.Southfield, MI 48075Main Station: (248) 557-2000Newsroom: (248) 552-5103


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COVENTRY — There's no question Coventry senior guard Nate Stitchell is the Oakers' best and most indispensable player.
It also comes as no surprise that the Oakers will only go far in the Division I tournament and the Open tournament as Garrett Douglass's outside shot and Aaron Greenwood's inside game will take them.
NARRAGANSETT–Education Commissioner Deborah Gist spent Thursday touring the town's schools and meeting for an hour with 50 teachers. The Board of Regents, meeting in Narragansett High School, voted to have a public hearing on their suggested three-tier diploma system. The system would award a Rhode Island diploma–the same diploma students now receive–with two additional tiers for high performers.
SOUTH KINGSTOWN–Due to its efforts to improve cardiac care and save lives, South Kingstown and its EMS Department became the third Rhode Island community to be awarded and recognized as a HeartSafe community at Monday night's town council meeting by the American Heart Association.
It was one and done for the Chariho Regional School District, which was entirely closed on Wednesday because of the massive blizzard but is back in business today after a one-hour delay.
There is a parking ban tomorrow morning, Thursday at 7 a.m. Coventry public schools as well as Sylvan Learning of Coventry: Canceled Classes
All East Greenwich schools and town government offices closed, as did the second shift for Stanley-Bostitch. The Warwick Mall was also closed.
North Kingstown and Exeter may have gotten off easy two weeks ago when a quick blizzard passed through the area and left a foot of snow that was picked up without much incident but today, Mother Nature returned with quite a vengeance as well over 15 inches of snow fell across Rhode Island and left areas as far south as Westerly and as far north as Cumberland coated in the white stuff.
So, how did you deal with the storm? Were the roads up to snuff on your commute? Leave a comment and let us know.
Boys basketball
Shea at Narragansett, 7 p.m.
Cranston West at South Kingstown, 7 p.m.
Mount Hope at Prout, 7 p.m.
Lincoln at West Warwick, 7 p.m.
Girls basketball
South Kingstown at Lincoln School, 5:30 p.m.
Prout at Mount Hope, 7 p.m.
Mount Hope at Coventry, 7 p.m.
South Kingstown, Burrillville at Warwick Veterans, 5:30 p.m.
North Kingstown Public Schools will be closed Wed. Jan. 12.
Jamestown Public Schools will be closed Wed. Jan. 12.
North Kingstown Free Library: Closed Wed 1/12 for storm
Parking Bans:
Jamestown: Parking ban this evening; UNTIL MIDNIGHT TOMORROW NIGHT
North Kingstown: Parking ban this evening; In effect at Midnight
Exeter: Exeter-Hope Val.-Pub Works: Parking Ban Tomorrow
CHARLESTOWN -- Despite the snowy weekend, a good sampling of District 36 voters came to Representative Donna Walsh's community meeting on Saturday, Jan. 8, 2011 at the Charlestown Police Station Community room.


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A new breed of horror. Wednesdays at 10pm.
The psychological illusionist performs amazing acts of mind magic. Starts 2nd Oct, 9pm.
See the final series on Thursdays at 9pm, only on Watch.
The people of Arcadia change forever when their deceased loved ones start to reappear.
Tinie Tempah and Sir Richard Branson are among the stars in this super-sized new series.
Abraham rushes to the scene to deliver a chilling warning to Dr. Ephraim Goodweather.
See what happened when Dynamo visited India and borrowed a sari for his epic street magic.
Gary, George and Matt take the helm of the ultimate cook-off series.
A supernatural medical drama starring Erica Durance, Daniel Gillies and Michael Shanks.
Are you a huge fan? Let's put your knowledge to the test.
Set yourself a challenge with our quiz about the people and events inside Hope Zion.
Enter for your chance to win a copy of Dynamo: Magician Impossible 3 on DVD.
Here's a full list of recent prize winners on Watch.


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Software Map
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Topic :: Drivers/Interfaces [Remove This Filter]
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|0. libpq for WindowsCE - The access sample application is offered with libpq for the client WindowsCE.
This can be made by a few changes by present PostgreSQL and wcecompat.
Registered: 2007-04-19 23:38
|1. pgstream - pgstream is a C++ front-end library for pgsql-7.4 or newer, mainly aimed at providing an easy C++ stream-based API to exchange data with the pg server
|Activity Percentile: 0.00
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Registered: 2004-10-11 14:40


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Click here for a list of
organisations accepting IELTS results.
Canada welcomes IELTS candidates
The Department of Citizenship and Immigration in Canada (CIC) announced it will continue to accept IELTS General Training as proof of English language ability...
The Department of Immigration (DOI) Cayman Islands has introduced a requirement for overseas English language testing (ELT) for prospective employees whose first language is not English.
Biometric systems further tighten IELTS test security
The IELTS test partners announce that biometric systems to verify the identity of test takers have been implemented globally...


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Published on April 11th, 2010 | by Chris Davids
The Beast Below – Reaction
Press reaction to The Beast Below has been limited to a single review in The Guardian/Observer so far – however the audience figures make interesting reading…
6.7 million viewers tuned in to The Beast Below according to overnight figures, but with a 34% audience share it is clear that despite the drop on the previous week, the majority of the available audience was tuned in to see the Doctor (Matt Smith) and Amy (Karen Gillan) encounter Liz Ten (Sophie Okonedo) and the bizarre secret of StarshipUK.
Nevetheless, Doctor Who was the most watched program on Saturday, with only the 7.6 million peak for the Grand National between 4.15pm and 4.30pm providing any competition.
Reviewed on The Guardian website, The Beast Below gets an overall positive reaction, with the selection of dialogue triumphs ("I'm the bloody Queen mate, and basically I rule") sitting alongside this observation:
The Beast Below looks for all the world like a RTD story: a Technicolor morality play light on intricate plotting and heavy on modern moral parallels. But Moffat still conjures some magical ideas and takes the characters exactly where they need to go…
We'll be updating this article throughout the next couple of days as new press reviews are published; look out also for our dedicated round up of blog reviews, while our own review of The Beast Below will be published later on Sunday.


text: OKLAHOMA CITY (Sept. 16, 2014) — State Superintendent of Public Instruction Janet Barresi recognized six Rising Star Teachers from across the state during today's state Teacher of the Year ceremony at the Oklahoma State Fair. Rising Stars are teachers who show an amazing amount of promise in their profession. They are selected in addition to the 12 finalists for the state Teacher of the Year.


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A porcupine sits in a cedar tree on Friday just off Remington Rd. southeast of Aulne.
Lisa Geis, Durham, cleans her pigs at the wash station at the Kansas State Fair on Sunday in preparation for the drive home. Lisa was declared 4th high senior swine showman at the state fair this year in addition to winning several other awards.
Jordan Smith, an eighth-grader at Centre, finished in first place Thursday at Abilene in the first cross-country meet of the season. She finished the course in 5 minutes, 56 seconds.
Barrett Smith, a 175-pound, 5-foot-7 junior, carries the ball early in the game Friday against Solomon at home. Smith was Centre's leading rusher, with 17 carries for 165 yards. He also scored the last two touchdowns.
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