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HGTV Message Boards
General Gardening
Hydrangea refuses to bloom! Help!
I planted three beautiful Forever and Ever Hydrangea at my last house and they bloomed for three years. Moved them to my new home and they have not bloomed since (two seasons). I've given them the same eastern elevation but all I get is leaves, lots and lots of leaves. What's wrong? TIA.
**Life isn't about waiting for the storm to pass...it's about learning to dance in the rain**
Where in the world are you?
What is the soil these Hydrangeas planted in like?
What does a good reliable soil test say about that soil?
The sign of a good gardener is not a green thumb, it is brown knees.
My question would be, have they pruned recently? I'm pretty sure the Forever and Ever variety are continual bloomers but it's always possible that they were shocked or something.
Happily married and mom of 4
Central maryland - Zone 7
So, I'm in Michigan, halfway between Detroit and Lansing. I have no clue as to soil type, but I only moved across town so it's probably not that different. Here's the thing, a Hydrangea that was already here (in the exact location where I planted the Forever and Evers), which I moved about 10 feet away, is blooming beautifully so I don't think soil is the issue. What else could it be?
**Life isn't about waiting for the storm to pass...it's about learning to dance in the rain**
RE: pruning...I pruned them when I moved them last year and I did think that might have been why they didn't bloom last year, but this year, I did not prune them...
**Life isn't about waiting for the storm to pass...it's about learning to dance in the rain**
I saw these tips for Forever and Ever:
They can be pruned at any time during the year without compromising the blooms for the season.
Beneficial Pruning for the plants:
1) Remove all dead stems from the plant each year.
2) After plant is at least 5 years old, 1/3 of the oldest stems can be pruned down to the ground each year. This type of pruning will help revitalize the plant.
Once all the old stems are removed, then shape the rest of the plant as desire
Suggested fertilizer: balanced, such as 10-10-10, following package directions.
I use Holly-tone organic fertilizer. For some reason, I had a hard time finding it this year. I sprinkle it around the plants in spring and maybe halfway thru the season. Whatever the package says. I haven't done it yet this year, but they have buds.
I actually am just getting around to fertilizing my Endless Summer because they were hit hard this year wo snow cover and then our 14" of snow May2. The green is just starting to come up from the ground and taking off. They were 4 ft around last year.
I would wait it out. Maybe they're just developing roots in their new home before they have the "power" to bloom. ???
You shouldn't, nor will it work....you cant feed a plant into submission. If it's not blooming...when all says it should...its for a reason and the soil its in is only one possible cause.
The problem at hand evidently is affecting not one plant...but three...it has to be something that is affecting all of them.
Soil...they're all in the same soil so that's one possible cause....something in the soil is causing the problem.
"lots and lots of leaves"....that tells us something. The plants are all being made to grow foliage...lots of it.
So it comes down to what causes that.
Fertilizer. High nitrogen fertilizer probably fed in the spring and no doubt when they were planted in their new home.
Usually, plants will put up a fuss when moved.
They have to get used to their new surroundings...soil, water, sun....all can have an affect.
But nitrogen from all that fertilizer given them tells the plant to grow leaves...and the plant likes it...it says, keep it comin....but don't count on bloom. It aint going to happen.
The best thing you can do for the plants is to STOP ALL FEEDING....ENTIRELY, until it does bloom, then be governed by its performance.
Watch the watering and make sure it drains well.
Whether there is time left for some flowering to appear this season is up in the air...but you should be able to count on next season.
You've been given some good advice thus far. I just wanted to add that hydrangeas hate to be moved so they really just might e getting used to their new home. Good luck!
My home and garden http://skylerhome.shutterfly.c.../?a=0AasWbFu1ctGLCUg
Thanks to all...
nance425 (I returned your PM), lots of good info, I appreciate it!
Loonie, since there are numerous flowering plants surrounding the hydrangeas, over use of nitrogen is not the problem.
Skyler, that's what I thought last year, but this year is just too long for it to be "moving trauma" methinks.
**Life isn't about waiting for the storm to pass...it's about learning to dance in the rain**
Belstone, I moved some 3 yrs. ago. I got my first bloom this year....and it was HUGE.
Mine don't get any fertilizer, so that wasn't a problem.
"The soil is the source of life, creativity, culture and real independence." David Ben-Gurion
Interesting...as I mentioned, I moved the hydrangea that came with house and while it wasn't very happy the first year, it did bloom and this year is gorgeous. I'm glad you posted as I was thinking I'd move them to the backyard and replace with new ones...maybe I'll give them another year? Thanks.
**Life isn't about waiting for the storm to pass...it's about learning to dance in the rain**
I have no idea, other than a soil problem?
I moved three of mine (that never ever bloomed) to a new spot last year and they LOVE it, blooming like crazy they are, so I'm not sure it's the moving thing, so much as a sunlight/soil thing.
The majority of plant problems I have seen over the years can be traced to the soil they are in. If you have clay soil, most common in your area, that can result in a too wet soil and Hydrangeas do not grow well in soils that are too wet. There can be a lot of difference in soils 10 feet apart. Perhaps this link will be of some help.
The sign of a good gardener is not a green thumb, it is brown knees.
That was helpful...we did have late frosts both this and last year...did a number on my Japanese Maple as well! Thanks KimmSr!
**Life isn't about waiting for the storm to pass...it's about learning to dance in the rain**
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I realize there's a raging debate about the consumer ethics of shopping on Thanksgiving, Black Friday and so forth. Still, in the interests of our mission - we have info to share with you.
First, please remember your OWN tote bags for your shopping. On the busiest shopping day of the year, imagine what you can do to reduce disposable bags with a few totes?
Second, we have found a list of (reported) freebies on Black Friday. These might be terrific gift items and also terrific items to donate. Walgreens and CVS in particular have a ton of free items that include many groceries you can share. You get the rewards on your in-store cards; your neighbors benefit from the items.
And if you are fortunate enough to receive a modest gift card as your "freebie" - perhaps consider purchasing some totes to donate? Or passing along the card to a project you support - you might be surprised how far we can make a $5 or $10 card stretch.
Are you aware of any other free tote offers? I'm surprised there aren't more of them.
So what to do with your bounty? First, put your totes in your car ...
Here's a list of spots accepting donations. If you donate food or groceries, please be sure to look for an indication that the spot can manage food.
And if you can take a minute around your own Thanksgiving gathering - perhaps suggest the family consider a holiday project? Its never too late to share.
Happy Thanksgiving!
The Pittsburgh Tote Bag Project collects new and gently used tote bags for distribution to the region's food pantries. We are a project of the Thomas Merton Center. Visit our website for a list of permanent drop-off spots, information on how to organize your own tote bag drive and details on our partnerships with corporations and promotional products items. You can also follow us on Twitter@Tote4Pgh and Facebook.com/Tote4pgh

subset: commoncrawl


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Savoir Embellished Tunic DressColour: Navy.
Savoir Embellished Waist Maxi Dress
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11 reviews
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Savoir Maxi Dress with Embellishment to Waist
This glamorous evening dress by Savoir is the ideal addition to your special occasion summer wardrobe with it's lightweight, silky feel and sleeveless design.
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Wear this maxi dress with a pair of Teatro peep toe heels, sparkling and delicate jewellery with an embellished clutch bag to complete your glamorous evening style.
Useful info:
- Evening maxi dress by Savoir
- Embellished detail to waist
- Soft, silky touch; lined
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- Length: 48 inches
Savoir Petite Simple Shift Dress
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Savoir Petite Simple Shift Dress
Structured pencil dress. Length 40 inch.Colours: Blue, Red. Machine washable.
Savoir Luxury Linen Pencil Dress
Mixing casual with elegance, this linen day dress by Savoir is the perfect pick for summertime soirees and garden parties with friends and family.
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Savoir Simple Shift Dress
Structured pencil dress length 40 inch.Colours: Blue, Red. Machine washable.
Savoir Embellished Linen Dress
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1 review
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Savoir Linen Shift Dress with Embellished Neckline
Celebrate sizzling summer style in this beautiful linen shift dress by Savoir - it's the perfect pick for daytime soirees.
Linen fabric is ultra light and comfy making this dress ideal for exploring new cities and making an entrance at daytime parties. The embellished neckline shimmers and sparkles as it catches the light, while the floral print works in a little summer inspiration for a feminine finish.
Wear this shift dress with a pair of leather tan wedge heels to lift your looks this season and finish with delicate jewellery to complete your summertime style.
Useful info:
- Linen shift dress by Savoir
- Embellished neckline
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- Length: 38 inches
Savoir Ruched Side Lace Dress
Jersey lace dress. Length 38 inch.Colours: Bronze, Navy/Nude. Shell: 93% polyamide, 7% elastane. Lining: Polyester. Machine washable.
Savoir Broderie Anglais Dress
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1 review
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Savoir Broderie Anglais Pencil Dress.
Length 40 inch.Colour: Navy. Cotton. Machine washable.
Savoir Cut-Out Detail Linen Dress
This linen dress by Savoir is a chic piece that adds a sophisticated edge to your summer wardrobe.
Linen is the perfect fabric for the approaching summer months - lightweight and cool it provides all day comfort. Floral cut-out detailing to the neck and hem add an intricate beauty, giving your style a unique twist. The sleeveless style is perfect for warmer weather and looks stylish layered with tailored seperates.
Wear this dress with Head Over Heels flat sandals and carry a Fiorelli tote bag for a elegant daytime outfit.
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- Linen dress by Savoir
- Cut-out detailing
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Savoir Stitch Knitted Dress
This knitted dress by Savoir adds a sweet and chic touch to your new season wardrobe.
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Wear this dress with Shoe Box heels and a classic trench coat for a daytime outfit you'll love wearing.
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- Dress by Savoir
- Textured knit detail
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Savoir Petite Mix and Match Dress
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Belt included.Colours: Navy, Stone. Shell: Polyester. Lining: Polyester. Machine washable.
Savoir Biker Confident Curves Dress
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23 reviews
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Savoir Confident Curves Biker Dress with Inner Corset
Show off your curves with confidence in this stunning biker inspired dress by Savoir. From their Confident Curves collection, this piece smoothes and sleeks for a striking result every time.
Featuring an inner corset this dress nips you in helping you accentuate your hourglass curves. The gentle stretch to the fabric ensures the fit is personalised and helps to smooth your silhouette. Quarter sleeves flatter your upper arms, while the functional side zip adds a subtle biker chick touch.
Available in blue or black have fun with this dress and pair the classic black with a pair of zesty orange court shoes and blue with a metal trim for the cobalt hue.
Useful info:
- Confident Curves Dress by Savoir
- Inner corset feature
- Quarter sleeve style
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- Gentle stretch to fabric
- Length: 40 inches


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Dynomite Game Overview
Get cracking! Aim your slingshot and fire away at a wall of eggs!Clear prehistoric eggs by matching three or more of the same color. In the Endless puzzle, the eggs never stop falling so you have to match fast. In the Stomped puzzle, every egg you explode incites Mama Brontosaurus, and when she gets really mad, she'll stomp and bring the eggs down a notch.
1.Select and click a puzzle -- Endless or Stomped, or Fossil Challenge, which is a Deluxe game download.
2.Select and click your skill level -- Normal, Hard, or Expert.
3.Click the Play button and fire your first egg to begin!
Having Trouble?
Tips and Strategies


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Chocolate Cake RecipeChocolate Cake Recipe3 years ago in Artisan Crafts More Like This
The Chocolate Cake With Excessively Thick Icing
Two 9 inch cake tins with removable bases
2 circles of greaseproof paper the size of your baking tins' bases
A large pan of water and a smaller pan (feel free to use a double boiler instead if you own one)
At least two mixing bowls
Whisk (normal or electric, a hand cranked one won't work!)
Cooling Rack
Ingredients (Sponge)
250g Margarine or Butter (suitable for baking)
200g Plain flour
50g Cocoa Powder
250g Caster Sugar
4 tsp. Baking Powder/Soda
4 eggs
2 tbsp. hot water
Ingredients (icing)
125g Butter or Margarine (only solid butter will do, no spreads or shortenings)
50-100g of cocoa powder (to taste)
50-100g icing sugar or white caster sugar (to taste)
Boiling Water
156ml whipping cream
200g Dark Chocolate
Preheat the oven to 180 degrees C.
Grease the tins and place the greaseproof paper on the base of each.
Chop up the butter or margarine (for the sponge) and plac


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Transcript Staff
The Norman Transcript
NORMAN — Norman Eagle Scout candidate Samuel Smith is hoping to donate a bronze statue of a wildcat to Alcott Middle School. The statue donation is part of Smith's Eagle Scout project. Smith is a candidate of Troop 20 who attends Alcott.
Local artist and sculptor Wade Heckes helped design and sculpt the wildcat, which will be posed atop a granite base. Heckes said he was eager to help, since he attended Alcott when it was called West Junior High.
"I thought that it was a great idea and project," Heckes said. "I believe that the Boy Scouts is a great organization, and I am pleased that I could help Samuel on his Eagle project. It will be something that I know will be there for years to come and is my way of giving back to the community."
Smith said he has learned that the process of creating a statue is more complicated than he thought. In addition to coordinating numerous things at one time, he is having to work within a timeline to complete the project before school is out for the summer.
Smith hopes the result of his hard work will boost morale and encourage pride at his school.
"I have gone to Alcott for three years," Smith said. "When thinking about selecting a project, I just wanted to give back to my school. It will give the students a more potent sense of pride and ownership for Alcott, the school that they are associated with."
The clay sculpture of the wildcat has been on display at the school. Once funding has been established, the sculpture will be sent to JSC Manufacturing Inc. in Wilson to be bronzed.
"Not only is it neat that we have a local artist helping me with the project, but if we get the whole community on this bandwagon, then it would truly be a community project," Smith said. "I know there are a lot of people who have attended Alcott, or West Junior High, as it used to be called, or that their children attended the school who would like to help make a statue of the mascot for the first time."
The approximate cost of the project is $5,000. Smith is accepting donations to help cover the cost of the project. Donations may be sent to Samuel Smith, 4304 Upper Lake Drive, Norman, OK 73072. Checks can be made out to BSA Troop 20, c/o Samuel Smith Eagle Project.
For local news and more, subscribe to The Norman Transcript Smart Edition, or our print edition.


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Alumni from the five schools of The Jewish Theological Seminary are invited to an evening of dinner and dialogue at the fourth annual JTS Delaware Valley Alumni Reunion. The event will take place at 6:30 p.m. on Sunday, November 23 at Temple Beth Hillel-Beth El, 1001 Remington Road, Wynnewood. Rabbi Daniel Nevins, Pearl Resnick Dean of The Rabbinical School of The Jewish Theological Seminary, will be the guest speaker.
The evening of reunion and friendship is being made possible through the generosity and vision of Yale Asbell, a member of the JTS Board of Trustees, and his wife, Audrey. JTS's five schools include The Rabbinical School, H.L. Miller Cantorial School and College of Jewish Music, Albert A. List College of Jewish Studies, The Graduate School, and the William Davidson Graduate School of Jewish Education.
In addition to serving as dean, Rabbi Nevins teaches homiletics, chairs the Department of Professional and Pastoral Skills, and serves on the chancellor's Academic Council. He is a member of the Executive Council of the Rabbinical Assembly, and serves on its Committee on Jewish Law and Standards. He has written responsa on the halakhic topics of personal status, disabilities, bioethics, and homosexuality.
Prior to joining JTS in 2007, Rabbi Nevins served as religious leader of Adat Shalom Synagogue in Farmington Hills, Michigan, for thirteen years. The author of a number of well-received articles and essays, Rabbi Nevins earned his bachelor's degree, magna cum laude, from Harvard College and his master's degree and rabbinic ordination from JTS. He received a graduate fellowship from the Wexner Foundation.
Reservations are requested by Monday, November 17. To RSVP or for further information, please contact Rickey Goodman at (215) 376-0474.


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Traverse City Record-Eagle
---- — KYLE EDWARD KEAN, 26 of Lake Ann, passed away unexpectedly on Wednesday, May 29, 2013 in Saginaw. A memorial service for Kyle will take place at 3:30 p.m, on Saturday, June 8, at the Reynolds-Jonkhoff Funeral Home. A complete obituary will follow in a later edition of the Record-Eagle. The family is being served by the Reynolds-Jonkhoff Funeral Home.
CHARLES L. STEFFENS, 75, of East Leland, died Saturday, June 1, 2013 at Tendercare of Leelanau. Visitation will be held from 5 to 8 p.m., Tuesday, June 4, at the Martinson Funeral Home of Suttons Bay. The funeral service will be held at 11 a.m. on Wednesday, June 5 with visitation one hour prior to the service at Immanuel Lutheran Church of Leland. Arrangements are with the Martinson Funeral Home of Suttons Bay.


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From the economic impact of the polar vortex to who will perform at next month's Super Bowl, here are five things you need to know for the coming week:
1. Luxury retailer Neiman Marcus joined Target as a victim of a cybersecurity attack over the holidays. Neiman Marcus confirmed on Saturday that customers' credit and debit card information may have been compromised, following evidence of hacking in mid-December. And on Friday, Target announced that its data breach over the holidays affected up to 70 million more customers than they first believed. The total number of people who potentially had their data stolen is now 110 million. It's unclear if the two security breaches are related.
2. The government may fire CGI Federal, the company that created the troubled HealthCare.gov. According to The Washington Post, federal health officials are preparing to sign a new a 12-month contract worth an estimated $90 million with Accenture, the consulting firm that built California's new health insurance exchange.
3. The Red Hot Chili Peppers will perform during this year's Super Bowl halftime show. The band will join Bruno Mars on the entertainment roster, Fox announced Saturday.
4. Your doctor asks you about your diet, exercise and smoking habits, but does he or she ask you about your drinking? Probably not, according to new Centers for Disease Control data showing just 1 in 6 adults reported any such conversation. Drinking too much, even if it's not indicative of alcoholism, can have serious effects on your health and safety. Go here for the CDC's most frequently asked booze questions.
5. Last week's polar vortex cost the economy about $5 billion, estimates the business weather intelligence firm Planalytics. The number, which includes everything from frozen water pipes to travel delays, would make the freeze the most expensive weather disaster since 2012's Superstorm Sandy, which cost $65 billion in property damage alone.


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12-Pk. Easton® XX75 Camo Hunter Shafts
Item # WX2-213954
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You must be 18 years of age to purchase this item.
This item is shipped directly from the factory. To see the expected shipping date, please add to your Shopping Cart. Sorry, no express shipping available. We are unable to ship factory direct items to Alaska, Hawaii, Puerto Rico or APO or FPO addresses.
Shipping restrictions apply to this product under some jurisdictions. Known age, state and local shipping requirements are applied at checkout and may result in changes to an order.
This item cannot ship to Canada.
This item cannot ship internationally.
- Details & Specs
12 Easton® XX75 Camo Hunter Shafts. With a factory-installed UNI Nock system and tough alloy shaft...
...this 12-Pk. is all about results! After all, when it comes to bowhunting, what else matters? The Super UNI Bushing acts as a buffer between the shaft and the nock to help reduce annoying "popped nocks" after a particularly strong shot. It also helps keep the nock in place for you tight shootin' William Tells who tend to hit the arrow from your previous shot during target practice.
The tough alloy shaft is dressed-up with hard-anodized camo for a cool look that'll last for many hunting seasons down the road. And just like every Arrow in the Easton® line-up, the Camo Hunter gives marksmen (and women) the best chance for successful shooting with superb straightness standards and excellent weight consistency.Easton and The Guide hit the mark once again:
- "X" Uni bushings and "X" nocks installed on sizes 1816, 1913 and 1916 all other sizes fitted with Super Nocks and Super-Uni Bushings
- Straightness: +/- .002" guaranteed
- Weight tolerance: +/- 1%
- Available in plenty of sizes.
State Size, as available in Shopping Cart.
Please Note: Arrow does NOT include fletching nor broad head. Custom Cutting NOT available on this item.
- Reviews
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100-Pk. of Allen 100 Grain Field PointsBuyer's Club $16.19 Non-Members $17.99
3-Pk. of Rage® X-treme 100-grain Chisel Tip BroadheadsBuyer's Club $40.49 Non-Members $44.99
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12-Pk. Easton® Power Flight ShaftsBuyer's Club $62.99 Non-Members $69.99


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The Final Shot: Photopass collection by Anika Mottershaw
A photographer's photopass collection by Anika Mottershaw.
We try and close out our featured content each day with an interesting picture from the musical world, mined from the libraries of our photographers and readers. We call this The Final Shot. If you'd like to contribute, please send your pictures to email@example.com at landscape, 960 pixels width.


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A good blend of sweet and sour this chutney goes well with any Indian curry.
115g/4oz coconut, freshly grated
110g/4oz chopped, fresh green coriander
1 small onion or 2 shallots peeled and coasley chopped
2.5cm/1in piece of fresh ginger, peeled and coarsely chopped
2 garlic cloves, peeled and coarsely chopped
2 tbsp lemon juice
1 tsp coriander seeds
2 cloves
1cm/½in piece of cinnamon stick
1 tsp salt
1 tsp sugar
Put the coconut, coriander, onion or shallot, ginger, garlic, chillies and lemon juice in a food processor. Blend, adding 4 tbsp water as needed to get a thick, coarse paste. You may, if you wish, put this mixture into the container of an electric blender in several batches to get a much finer paste, adding a little water if needed.
Put the coriander seeds, cloves and cinnamon into a clean coffee grinder and grind them to a fine powder. Mix the powder with the coconut mixture. Add the salt and sugar. Stir to mix and taste for the blend of sweet and sour. Cover and refrigerate until needed.
The chutney lasts 24-36 hours. It may also be frozen.
Type the ingredients you want to use, then click Go. For better results you can use quotation marks around phrases (e.g. "chicken breast"). Alternatively you can search by chef, programme, cuisine, diet, or dish (e.g. Lasagne).
BBC © 2014 The BBC is not responsible for the content of external sites. Read more.
This page is best viewed in an up-to-date web browser with style sheets (CSS) enabled. While you will be able to view the content of this page in your current browser, you will not be able to get the full visual experience. Please consider upgrading your browser software or enabling style sheets (CSS) if you are able to do so.


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Catch the Purple Fever!
January 30, 2013
Time: 2:45 PM - 3:15 PM
Location: William H. Thumel Sr. Business Center Atrium
Contact Name: Danielle Giles
Contact Phone: 410.837.4955
Contact E-mail: email@example.com
Please join the Merrick School of Business in celebrating our hometown team the Baltimore Ravens and their march towards a Super Bowl victory!
Come in your best purple attire, Ravens jerseys, sweatshirts, t-shirts and rally gear! And don't hold back, purple feather boas, beads, etc encouraged.
- Light refreshments will be served.
- A group photo will be take around 3 p.m. so come early!


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A handful of area voters got the opportunity last night to dive a bit deeper into the debate surrounding Question 7, which could allow a casino to operate in Prince George's County and bring Vegas-style table games to casinos across the state.
Gathered in a first-floor conference room in the Hyattsville Municipal Building, they were here to consider the two sides of the argument in a manner more thoughtful than what might be available to a typical voter in the midst of one of the most expensive political campaigns waged in Maryland in recent memory.
Arguing in favor of expanded gambling was Brad Frome, deputy chief of staff to Prince George's County Executive Rushern Baker.
His argument focused on three projected benefits which a casino in Prince George's County would bring: jobs, and increased local tax revenues and education funding.
Arguing against the proposal was Del. Doyle Niemann (D-District 47), of Mount Rainier.
He argued that expanded gambling in Prince George's County would not bring in the amount of tax revenues which gambling proponents claim and he was also critical of the social cost–the effects of gambling addiction, for instance–which local governments might have to deal with if Question 7 passes.
The debate was moderated by Hyattsville resident Jim Groves. Each side had 20 minutes at the outset to lay out their arguments. That was followed by a town hall-style question and answer session moderated by Groves
Frome opened up the debate by noting the expansion of gambling in Delaware, West Virginia and Pennsylvania over the last decade. He said that Marylanders were leaving the state in droves to dance with lady luck.
"The facts on the ground dictate that all of this money was leaving the state," said Frome during his opening statement
Frome then highlighted the National Harbor site, which is being eyed by Baker as a potential site for a new billion dollar MGM casino. Its location, on the edge of the Potomac River, just south of Washington, DC and across the river from Alexandria, made it a perfect location for a glitzy casino, said Frome.
"We're next to the largest tourist destination in the nation," said Frome. "41 Million visitors. We have the potential to have a facility that is a major destination.
But while Frome had earlier bemoaned the fact that Marylanders had to go outside of the state to play table games, he projected that the vast majority of casino customers, between 75 and 80 percent of them, would be out of state tourists.
Frome also stressed the economic benefits which a Prince George's County casino might bring, predicting that the facility would require 2,000 construction jobs and 4,000 permanent jobs to operate. Anticipating the argument that the jobs at a casino might be, for whatever reason, undesirable, Frome said that while some casino jobs might not require advanced degrees, they are still jobs.
"For a lot of folks, that job is an opportunity that they didn't have before," said Frome. "For a lot of folks who don't have an education, who don't have a lot in life, that is an opportunity."
Frome also said that the casino would directly and indirectly generate much needed revenue for the county government. Not only would the county see a roughly five-percent local cut of gambling tax revenues, argued Frome, but also the property taxes on the casino site, income tax from casino employees living in the county and increased amusement and hotel tax revenues. As a result, Frome predicted county would see a total of $41.4 million in new tax revenues if the casino moved forward.
"That's the equivalent of raising everybody's property tax rates by 10 percent," said Frome, noting that the county was at or near the limit it can charge for property, income and telecommunications taxes.
Nieman, in his arguments, said that the gambling bill was not a good deal for the state or the county and that the past promises of gambling proponents have fallen short of projections.
"It's just not worth it," said Nieman, who said that the tax revenues would be coming from nearly $590 million in money lost at slots and table games by visitors to the casino. "We talk about these revenues as if the casino's were selling widgets, but it's based on what people lose…the house always wins if you bet long enough."
Nieman said that the average gambler walks out of a casino with half of the money they brought into it.
Nieman also argued that the county would be better served by devoting resources to attracting government jobs and development around area Metro stations and a more robust effort to attract high-skilled private sector jobs to the county, instead of efforts to attract a casino.
"What kind of economic development do we want? We're now pulling money out of the economy where it is spent in different ways and putting it into an industry that really produces no value, whose only purpose is that we can tax it," said Nieman after the debate.
Niemann, during the debate, revealed that his father was a problem gambler. While his family never lost the farm on a bet, he did fear the impact that an increase in gambling addiction-related problems like foreclosures and crime which a casino in Prince George's might bring.
"One of the things that concerns me about the bill is the 24 hour gambling," said Nieman. "At four in the morning, you are not getting tourists to come in. You're getting locals. You don't have an opportunity to go home at 2 a.m. and think about all the money you've lost."
Nieman was also critical of how much power the gambling industry might come to hold in Maryland and Prince George's County if the bill passed, saying that the tax revenues would essentially force government officials to bend to the will of the casinos on some policy matters.
"The more we go down this path, the more we go down this path," said Nieman. "Because there is so much money involved."


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July News from PCAN
Portsmouth Summer Fair 30th August
Martin Fido is well under way with organising our PCAN Summer Fair and it's going to be great.
So if you are involved with other groups so let your members know and think about booking a stall as soon as you can.
We have a Facebook events page which makes it easy for you all to cascade it out to your friends! Find it from our PCAN page or from here
We also now have web banners and flyers so PLEASE get in touch if you can help us by sharing these.
And don't forget we'll need help on the day
Natalie Bennett
The leader of the Green Party is speaking at a public meeting in Petersfield on Friday 4th July. It's at St Peter's Parish Hall, St Peter's Road. Petersfield 7.15 for 7.30
Our next PCAN Meeting is on 30th July and the one after that is 17th September both at 7.30 in the King St Tavern, 70 King St, Southsea, PO5 4EH
Do come if you can
Time to Act on Climate Change
The Campaign Against Climate Change is asking us all to join them on March 7th 2015 in a mass creative action and march on the streets of London, to tell politicians: So make a note of the date now.
In the run-up to the 2015 election and at the international climate change summit in Paris in December 2015, the Time to Act on Climate Change campaign has a clear message - the urgent need for effective action to tackle climate change. We know what we need to do. We need to move:
¨ From exploitation to climate justice: UK support for a just international climate deal.
¨ From delay to action: 10% emissions cuts year on year, creating at least one million climate jobs.
¨ From fracking & fossil fuels to renewable energy: for all our needs.
¨ From cold homes and energy waste to insulation for all.
If you saw the recent films at Portsmouth's Green Film Festival you might be interested in this petition to stop the European Parliament letting Monsanto peddle its genetically modified crops all over Europe -- including places where it has been banned.
The petition text is: MEPs: take a stand for bees, birds and democracy, and vote against the proposal to allow GM crops to be grown in Europe." Take action here
Food partnership conference
If you missed the recent Portsmouth Food Partnership stakeholder meeting, you can find a copy of the presentations here.
In the course of the next few weeks, a multidisciplinary group will be invited to join the steering group to formally agree and finalise a Food Charter and begin generating the Action Plan, ready for an Autumn meeting.
For the Love of…
The Climate Coalition are getting people to share ideas of things people love which may be affected by climate Change and have a new For The Love Of.. website, Check it out here
For The Love Of.. Film
They have also produced a film highlighting the diverse and unexpected everyday things that are affected by climate change, and that people have already put up on the site.
We can send you the video file separately if you want to use it at any of your events, just get in touch.
See the film here:or they can send the video file separately for events
Showing our love on 21st September
They are also planning to make a public show of our love in Autumn, ahead of the Climate Leaders' summit in New York. It will be an opportunity to highlight support for our Government to show some much needed ambition on climate. They'll be teaming up with Avaaz, who are organising a people's march in London to link with a huge march in New York on Sunday 21st September, as well as other cities, on the same day.
The Plan: On Sunday 21st September we'll bring supporters together to show their love on the Thames, with boats representing 5 of the things that supporters have said they love through the medium of massive inflatables! This will of course represent the diversity of the coalition and will include Fairtrade food, wildlife, family and hobbies/ sports. Once the boats have docked the teams with their inflatables will come together with other coalition supporters, and spread some love on the Avaaz march in the afternoon.
There'll be loads of fun ways to get your supporters involved in the lead up and we'll have an event-brite page set up in mid July. http://fortheloveof.org.uk/
The Climate Coalition's AGM is on 15th July in London
Stuff and happiness: is it a choice between economic growth and well-being?
Tuesday 8 July, 7.30-9.15pm
United Church, Jewry Street, Winchester, SO23 8RZ
A joint WinACC/Friends of the Earth meeting.
Free, open to all. Refreshments from 7.15pm.
Hampshire Climate Action Network
This is a new network of campaigning groups around the County. They are planning a get-together of Hampshire groups on 18th October in Basingstoke. Anyone like to be on a very small time-limited group (meeting mostly by email or telephone conference) to plan this?
Transatlantic Trade Treaty
Take back the power – make trade work for people and planet
Transatlantic trade deals currently being negotiated, threaten to do the exact opposite. Investor dispute mechanisms will allow secret courts to overrule democratically made decisions if they are not considered in the interests of large corporations.
The US and the EU are negotiating a new trade agreement - TTIP - which amounts to the biggest transfer of power to corporations seen in recent years.
The Transatlantic Trade and Investment Partnership (TTIP) aims to liberalise the market between the US and the EU and remove barriers to trade. Its existence was leaked in March this year and exposed by a German newspaper. It's currently at the stage of negotiation 'cycling' between officials in Europe and the States, and has come under fire for being conducted with a complete lack of transparency. The process is due to conclude by 2014/2015.
Our democracy, public services and environment are under threat. If agreed, TTIP would extend the power of big business over our society to unprecedented levels. Shamefully, the UK government are currently a major supporter. But together, we can defeat this agreement.
On 12 July 2014, people across the UK will be taking action to say no to TTIP.
Join the #noTTIP day of action.
Day of Action: 12th July 2014
Download a pack of action ideas here
See here to get involved.
Oxfam Lifting Lives
Oxfam campaigners are focusing on climate change now – see the Too Much Weather link from this site
Get the banks out of coal
The UK financial sector is funding a coal boom in the global south with investments worth billions of pounds. Join WDM in calling for tougher regulation on coal finance.
Ideal World 2030
Have a look at this site where you can post your thoughts about an ideal world to be delivered to the UN Climate talks
Don't forget
We're happy to advertise your green events
You can follow us on Facebook. 'Like' our page for updates: PCAN
Find us on Twitter @portsmouthcan
We try and post as many relevant articles as we can on our twitter account @portsmouthCAN so do sign up to that and you can see the archive of posts.
Last Updated (Wednesday, 16 July 2014 17:42)


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Shoppers look for costumes for Halloween.
With halloween just two days away, many people are scrambling to get their costumes. Trick or Treaters of all ages want that perfect look for friday night.
Shoppers stopped in the Center Stage and Simply Unforgettable Costume shops to grab last minute items.
Managers from various stores saying the most popular costumes selling fast are The Joker and super heroes for men and Sarah Palin being the chose for ladies. Owners say they expect the crowds to get even busier and the lines a little longer. Center Stage Manager, John Albritton says, " We have two kinds of shoppers, the kind that prepare months in advance and know what they want. We have the kind that come in the last minute, like this week. It's Halloween, I got to get something.".
Both costume stores will be open for regular business hours on friday.
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Style Guides
APA Formatting and Style Guide (Purdue)
See this online quick guide.
Publication Manual of the American Psychological Association
Call Number: Reference BF76.7 .P83 2010
APA Style Guide to Electronic References
Call Number: Reference BF76.7 .P831 2007
Writing with Style: APA Style for Social Work
Call Number: Reference HM586 .S98 2004
Writing Tools
Writing Literature Reviews
Call Number: H61.8 .G3 2009
Publication Date: 2009-01-01
Articles relevant to Social Work can be found in multiple databases, including newspaper collections. The first two below are your best bets to get started; check the others for more focused research, or see the Topics tab.
- Social Services AbstractsFind current research about social services and welfare, including mental health services, crisis intervention, evaluation research, gerontology, policy and planning, poverty and homelessness, violence, and more.
- Academic Search PremierWith both scholarly and popular articles, this database is great for multidisciplinary topics, including social work issues from different perspectives.
- PsycINFO / PsycArticlesWith articles and books, PsycINFO covers all aspects of psychology. Use it for social work topics that overlap with psychology, mental health, mental disabilities, addictions, and more.
- Sociological AbstractsFind sociological research, including family and social welfare, substance abuse, criminology, health, social development, and more.
- DSM 5 (The Diagnostic and Statistical Manual of Mental Disorders)PsychiatryOnline contains the DSM library. The Diagnostic and Statistical Manual of Mental Disorders (DSM) is the standard classification of mental disorders used by mental health professionals in the United States. This site contains online access for the DSM V. Site also includes electronic access to all the previous editions of the DSM.
- Political Science CompleteThis is an excellent place to research the laws, legislation and the politics behind most social issues, nationally and internationally.
- CQ ResearcherThough not considered scholarly, this is a great source for easy-to-understand overviews of contemporary issues, including social services, disability, health, human rights, etc.
- ProQuest NewspapersUse newspaper articles to find local perspectives (both policy and opinion). Here you can find the Star Tribune and other major U.S. newspapers, including the Wall Street Journal and New York Times.
- LexisNexis AcademicGreat for comparing policy in foreign countries, LexisNexis provides full-text coverage of major national and foreign newspapers. It also includes TV and radio transcripts and federal and state cases and codes.
- No full text? Click "Find It" by the article to get it elsewhere, or to order it (learn more).
Explore a wide range of Social Work topics using the books below.
Encyclopedia of Social Work
Call Number: Reference HV35 .S6 v. 1–4
Use it online!
This superb set is a great place to start investigating all aspects of social work: social policy and history, practice and interventions, social environments, and social conditions and challenges.
This superb set is a great place to start investigating all aspects of social work: social policy and history, practice and interventions, social environments, and social conditions and challenges.
Comprehensive Handbook of Social Work and Social Welfare
Call Number: Reference HV40 .C635 2008 v. 1–4
Your go-to source for in-depth discussions, here you can find the basics of the profession (v. 1); theory (v. 2); assessment, intervention, and specific populations (v. 3); and social policy (v. 4).
Encyclopedia of Social Work with Groups
Call Number: Reference HV45 .E53 2009
Find a comprehensive overview of different group work approaches, working with specific populations and ages, and more.
Encyclopedia of Canadian Social Work
Call Number: Reference HV12 .C36 2005
Explore hundreds of diverse social work and welfare topics in the Canadian context.
Encyclopedia of Counseling
Call Number: Reference BF636.54 .E53 2008 v. 1–4
Find a comprehensive overview of the major theories, approaches, and contemporary issues in counseling. Volume 3 in particular focuses on cross-cultural issues.
International Encyclopedia of the Social Sciences
Call Number: Reference H40.A2 I5 2008 v. 1–9
This enormous set covers all aspects of the social sciences. See the articles on "Social Issues and Policy" in v. 1, p. CXLIX for places to start.
Social Work Diagnosis in Contemporary Practice
Call Number: Third Level HV40 .S6178 2005
With a focus on diagnostic skill development, this work underscores developmental stages, various situations, diverse populations, and innovative approaches to practice.
Web Resources
- National Association of Social Workers Research PageThe NASW provides information to inform policy, practice, and education. Find reports and links to other organizations for dozens of topics such as child welfare, homelessness, mental health, poverty, AIDS, veterans, etc.
- The Urban InstituteThe Urban Institute conducts research to foster sound public policy. Check out their reports and fact sheets by topic and their handy Policy Jargon Decorder, a glossary of common policy terms, legislation, and acronyms.
- Amhest H. Wilder FoundationThis St. Paul health and human services organization provides and promotes social welfare for the poor, youth, the elderly, and others. See their research reports and learn more about their programs.
- Greater Twin Cities United WayThe United Way connects people to various social services in the community. Find reports, learn about Twin Cities poverty, and check out the 2-1-1 service (formerly First Call for Help).
- Hennepin County Health, Housing, and Social ServicesFind information on various social services in Hennepin County, including adoption, abuse and neglect, homelessness, mental health, and much more.
- Ramsey County Community Human ServicesLearn how Ramsey County serves children and families, the low income and homeless, the elderly, the chemically dependent, people with disabilities, and the mentally ill.


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Ten years ago, this was a different city.
In the last year alone, Kansas City saw a change in leadership with a new mayor, then a new Police Chief; plus, the opening of another world-class performing arts center.
So, what could this city see in another year? Another five?
Many of the city's fountains were turned on Tuesday, following the annual Fountain Day celebration. The ceremony was held at the Marlborough Fountain, located at 79th and Paseo.
Looking for something to do this weekend? Up to Date's Brian McTavish offers up a few options in his Weekend To-Do List for April 13-15, 2012.
Kansas City Royals vs. Cleveland Indians: Royals' home-opening weekend. 3:10 p.m. Friday, 6:10 p.m. Saturday and 1:10 p.m. Sunday at Kauffman Stadium. Tickets: $10 to $245.
It's a popular saying in our town that only Rome has more public fountains than Kansas City.
How is Kansas City doing when it comes to attracting conventions and tourists to town?
A storm warning has been sent to Kansas City by a city department that performs much of the snow plowing during and after major winter storms.
Looking for something to do this weekend? Up to Date's Brian McTavish offers up a few options in his Weekend To-Do List for February 24-26, 2012.
Each year the Historic Kansas City Foundation releases a list of the "most endangered" structures in an effort to raise awareness of the city's historic buildings.
Looking for a few things to get your attention this weekend? Up to Date's Brian McTavish offers up a few options in his Weekend To-Do List for January 20-22, 2012.
A requested tax break for the reborn effort to develop the Plaza West Edge project breezed through a joint city council committee Wednesday.
Kansas City, Missouri City Manager Troy Schulte's recently proposed budget recommendations for 2012 include a number of cuts, most notably a reduction of more than 100 positions in the fire department. On Wednesday, Fire Chief Smokey Dyer told the City Council's public safety committee that the proposed cuts would violate national fire safety standards.
Even if you can't keep your New Year's resolutions, you can certainly make some short-term promises to go out on the town this weekend. Need some ideas? Brian McTavish is back to offer up a few options in his Weekend To-Do List for January 20-22, 2012.
The Kansas City (Missouri) Police Department searched far and wide for a new chief last year. Finally, they chose from within its ranks: Darryl Forté.
Tuesday on Up to Date, Steve Kraske welcomed Chief Forté to talk about Kansas City's consistently-high homicide rate, community policing, and his background.
North Kansas City took the first step toward creating a new sprawling business development Thursday, when a demolition crew began destroying a century-old Archer Daniels Midland mill.
The hulking gray mill sits on 58 acres of prime land at the intersection of 210 highway and I-35. The city hopes a developer will re-tool the land and create a large mixed-use development that could include medical offices, retail stores and possibly even some residential units.
Ready to face the great urban outdoors this weekend? Brian McTavish is back to offer up a few options in his Weekend To-Do List for January 13-14, 2012.
Whether it's the opening of a beacon of the performing arts, a shopping mall revived from near death, a business fleeing one side of the state for the other, or a law firm's attempt to build a new office structure on the Country Club Plaza, it's been a busy year in development across the Kansas City region.
Just three years ago the Kansas City Missouri City Council voted down a single-terminal plan for Kansas City International Airport. Now it has approved a $4.4 million study to determine how to build and pay for the very same thing. Why the change of heart and how is one terminal better than three?
KANSAS CITY, MO. (KCUR) - When the Kansas City Star used a federal database this summerto investigate the way doctors are monitored in the region, and matched anonymous records from the database to a specific doctor, the U.S. Department of Health and Human Services responded by, among other things, restricting access to the entire public database.
Sometimes truth is stranger than fiction, or fiction can illuminate truths. Lawrence-based artist Judith Levy collapses the two, and reimagines history in an exhibition called The Last Descendants.
By Laura Spencer
Kansas City, Mo. – Sometimes truth is stranger than fiction, or fiction can illuminate truths. Lawrence-based artist Judith Levy collapses the two, and reimagines history in an exhibition called The Last Descendants.
Renovations of the police communications building mean that a well-known statue will have to find a new home. Will it be sent to storage or be moved to another public spot in Kansas City? The debate is on!
By Sylvia Maria Gross, Laura Spencer, Brenna Daldorph
Kansas City, MO – The U.S. Postal Service has taken wraps off two commemorative stamps honoring baseball leagues that led the way toward racial integration. The stamp issue came at the Kansas City Negro Leagues Baseball Museum.
Thurgood Marshall Jr. of the Postal board of Governors noted how Jackie Robinson's 1947 breaking of the color line led to integration of sports and society and politics.
Anaheim, CA – Kansas City Royals relief pitcher Joakim Soria may be the long team representative at the All-Star game in Anaheim. But he's being more recognized by his fellow countrymen in Mexico. KCUR's Greg Echlin has more.
Kansas City, Mo. – Kansas City police waited for a search warrant today before examining the interior of a house in the upscale Country Club District where the homeowner was found dead this morning. Police identify him as 49 year old Michael J. Tutera. Investigators did not say by what means he was killed, except to say it is a homicide.
Police asked anyone with information to call the Crimestoppers' Hotline at 816-474-TIPS. A police spokesman said detectives were following up on what were termed, "good leads."


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After 22 years with The Tonight Show, Jay Leno has said goodbye to the late night show… again.
Leno has hosted the show for years — except for a brief stint in 2009 when he was let go and replaced by Conan O'Brien — after taking over for Johnny Carson.
He has called the gig as Tonight host "the greatest 22 years of my life."
Watch the video above to see Leno's final monologue, in case you missed it Thursday night.
The Tonight Show will move to New York City with a new host — Jimmy Fallon.
"I'm really excited for Jimmy Fallon. It's fun to be the old guy and see where the next generation takes this great institution," he said. "And in conclusion, I want to quote Johnny Carson: 'I bid you all a heartfelt good night.' "Will you miss Jay as host of Tonight? Or do you think it's time for a new host? Tell us in the comments below!


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Book online for ticketed events
One of the biggest Museum stores in the country, holding the reserve collections for Birmingham Museums Trust.
See inside Birmingham Museum & Art Gallery on a virtual tour.
A comprehensive guide to what's happening at Birmingham's museums.
Location: Soho House
25th July 2014 - 25th July 2014
Join us as we host are first Arts Health and Well-being Event! 12.00 noon - 4.00pm
Join us at Soho House 12.00 noon - 4.00pm as we host are first Arts Health and Wellbeing Event!
Throughout the day we will have with a range of information, advice stalls, presentations and workshops including
There is something for everyone! Will also have children's games & trail running throughout the day with loads of prizes to be won!


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Investigators with the North Charleston Fire Department have determined where the fire which ripped through an apartment complex on Delta Street Monday originated.
Fire department spokesperson Bianca Sancic said Friday investigators found the fire at the Delta Oaks Apartments began in the kitchen of apartment 212, but the specific cause of the fire is still undetermined.
Emergency crews responded to the apartments on the 5100 block of Delta Street just before 5 p.m. on Nov. 26.
Fire crews from North Charleston, Charleston, St. Andrews and St. John's responded to the two-story building fire. At one point authorities had shut down I-526 at Rivers Avenue because of the fire.
The fire destroyed 14 units of the apartment.
No one was injured. The American Red Cross is assisting nine families.
The North Charleston Fire Department would like to remind residents that the kitchen is the most likely location for a fire and that cooking is the most common cause of fire in the United States and in the city.
Copyright 2012 WCSC. All rights reserved.
2126 Charlie Hall Boulevard
Charleston, SC 29414
(843) 402-5555
FCC Public File
(843) 402-5555
EEO Report
Closed Captioning


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The Bottom
It's 1997. I'm a musician and find myself in Knoxville as the opening act for legendary Talking Heads frontman David Byrne. David and I had been exploring the seedy old downtown area around Gay Street when we came upon Walter's train wreck of misguided commerce: part barbershop, part thrift store, and, due to the presence of dozens of crudely carved wooden owls of all shape and size that populate the forward area of the shop, part folk-art emporium. ... It's just Walter and me now. Poor David fled the premises a few moments into our visit after being accused by Walter of conspiring to commit petty theft. ...
—Jim White, Radio Silence, "A New Magazine of Literature and Rock & Roll," maintainradiosilence.com
© 2012 MetroPulse. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Gary Cooper has owned at least 23 street rods, but his favorites have always been '34 Ford coupes. He has owned this Emerald Green 5-window for five years and says it's the one car that will never be put up for sale. It was originally built in California for a music industry CEO.
Link to image | Buy this photo
Mike Berry / The Wichita Eagle


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Steven Whitney scored the lone goal in the overtime shootout to help lead the Norfolk Admirals to 5-4 victory over the Springfield Falcons Friday night at Scope.
The game got off to a hot start when Springfields Frederic St. Denis scored on a rocket from the point to jump out to an early 1-0 lead. St. Deniss shot flew through traffic in front of the net and slipped past the left should of Norfolk netmninder John Gibson for the goal at 3:45 of the opening period.
It didnt take long for Norfolk to respond. The Admirals tested Springfields Mike Clemente early in his first start of the season, throwing pucks at the net relentlessly.


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SALISBURY, N.C. - Food Lion stores are accepting customers' Flexible Spending Account or Healthcare Reimbursement Account cards at all store registers. The transaction process will automatically deduct the cost of FSA/HRA items from a customer's total grocery bill once the card has been entered into the payment process.
ATLANTA (AP) -- The largest health insurer in the state has sent letters containing personal information to the wrong addresses, exposing more than 200,000 Georgians to possible identity theft.
The president pro tem of the Georgia Senate, Sen. Eric Johnson (D-Savannah), attended a reception the Hinesville Dialysis clinic on June 30.
At the end of June, the Coastal Health District began a pilot nicotine therapy replacement program to help local residents quit smoking.
Rep. Ron Stephens, who represents part of Liberty County, recently was honored by the Georgia Association of Emergency Medical Services, a statewide association representing more than 14,000 EMS professionals in Georgia.
As part of the Alpha Kappa Alpha sorority's "Health Resource Management and Economics" national program, the local Nu Rho Omega chapter sponsored two childhood obesity workshops in March.
SAVANNAH -- With sharp fuel prices biting into the grocery checkout line, Patti Moreno, garden expert with Farmers' Almanac, the original sustainable living guide, suggests consumers can save money, eat healthier and help protect the environment by growing their food at home.
ATLANTA - For most people, the summer means weeks of fun and travel. For the American Red Cross and thousands of hospital patients, however, this is a time of high anxiety. The summer traditionally means decreased blood donations, which result in a shortage of the blood types hospitals urgently need to treat trauma victims and other patients.
Hinesville Mayor Jim Thomas and the Chamber of Commerce board of directors joined Dr. Roger Myers and his staff in a ribbon-cutting ceremony July 10 for the opening of the city's newest oral surgery dental office.
Thursday morning, county and Coastal Health district officials gathered at the Fraser Center in Hinesville to discuss the proper course of action if the district were to be affected by a flu or avian flu pandemic. The tabletop exercise, which is being held in every county in the state, was hosted by the Coastal Health District and had an "excellent turnout," according to Annette Neu, who led the group's discussion.
The Liberty County Chamber of Commerce held their Progress Through People Luncheon last Thursday, which provided an eye-opening look at the state of health care within our community. Russ Toal spoke about the three Ring Healthcare Consortium and its mission.
The employees of Coastal Electric Cooperative off Highway 17 in Midway were more than happy to roll up their sleeves Thursday as the company sponsored an American Red Cross Blood Drive from 2-7 p.m.
The nation's emergency departments are in crisis due to overcrowding, which threatens access to emergency services for those who need them most. In its ongoing effort to better serve emergent patients, lower wait times and provide better customer service, Liberty Regional Medical Center will be implementing a new program called Early Medical Screening for Low Acuity Patients (EMLA).
Several of my friends and I have been absolutely amazed at the stories on the news and Web sites of extreme bullying among youth.
JESUP - Wayne/St. Joseph's/Candler Medical Group recently secured the services of cardiologist Dr. Gary Stern for the Jesup and Southeast Georgia areas.
JESUP - Student leaders at Wayne County High School recently educated their peers on the importance of injury prevention and shared data related to young children's emergency-room visits.
ATLANTA - The Association County Commissioners of Georgia and the Coast2CoastRx program save residents $4.6 million on their prescriptions with the Coast2Coast Rx card, a free discount prescription initiative.
Two years ago, I woke up knowing it was the day of my dreaded annual health checkup. I got my son Corey up for school.
The Liberty Regional Emergency Medical Services crew works unpredictable shifts, watches the sun set and rise in one shift and witnesses horrible things while working, yet these paramedics and EMTs still love their jobs.
BRUNSWICK - The Southeast Georgia Health System Auxiliaries recently named Elena "Lea" Taylor and Pearl Sophia Stephen as the volunteers of the quarter at the Brunswick and Camden campuses, respectively, during their quarterly auxiliary luncheons.


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Velvet Furniture Protectors
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This was sent to me by an old friend and client and I knew I had to share this one around the community.
Jump to content
Posted 06 April 2013 - 01:29 PM
This was sent to me by an old friend and client and I knew I had to share this one around the community.
Posted 06 April 2013 - 04:10 PM
I experienced a similar situation,
recovering a abandoned long line on the seabed i found a exhausted nurse shark attached to it.
Considering his/her state being almost unconscious from fighting to become free i decided to risk and try to free him/her.
I had my GoPro running clipped on my bcd but in the situation i did not think to hand the camera to Iris to get some better pictures. :-(
So please excuse the real bad quality!
Edited by ChrigelKarrer, 06 April 2013 - 04:12 PM.
Nikon D800 - Sigma 15mm - Nikon 105mm Micro VR - Hugyfot Housing - 3 Inon Z-240 strobes - 2x2 8'' ULCS arms
Canon G12 with Patima aluminium housing - Fuji E900 with Ikelite housing
Visit My Costa Rica Website - Visit My Italy Website
Posted 06 April 2013 - 04:13 PM
That was incredible! A wild Dolphin? I am totally amazed.
Proprietor of Scubacam, Singapore. Commercial videocameraman. Also shoot digital stills. I modify and built stuff. I love technology. Camera: Red Epic/ Scarlet and soon Dragon
Email: email@example.com
Posted 06 April 2013 - 06:31 PM
Amazing clip
Sony XR500 - LMI Stingray+ G2 - 2x LMI Sola 4000 LEDs
Liquidguru's Website
My weekly Blog from Ambon, Indonesia
Posted 06 April 2013 - 07:30 PM
Very touching moment. Thanks for sharing!
Edited by danielstassen, 06 April 2013 - 07:30 PM.
Posted 07 April 2013 - 06:30 AM
Edited by Ronyx, 07 April 2013 - 06:45 AM.


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Viridian C5L Green Laser Sight 100 Lumen Tactical Flashlight with TacLoc ECR Holster for Springfield XD/XDM Black
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Product Information
The Viridian C5L 5mW Green Laser with Flashlight is the world's only subcompact weapon mountable green laser with a built-in light. It is so tiny that it tucks neatly between trigger guard and muzzle, with no overhang, and will work not just with subcompacts but with virtually any railed gun. The light has an output of 100 lumens. Included with the laser are a TacLoc ECR Holster, CR2 battery, 3 unique rail sets, 1 rail set pin removal tool, 2 adjustment wrenches, 2 mounting screws and a operator's manual.
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Battery Type: CR2 3V Lithium
Battery Life: 4+ hours (constant), 7+ hours (pulse mode), 1+ hours (Laser & Light)
Light Output: 100 Lumen
Laser Output: 5mW Laser
Laser Range: 100 yds (Daylight), 2 Miles (Night)
Holster Fit: Springfield XD/XDM
Warranty: 1-year factory warranty
ECR equipped for use with TacLoc Holster
Covered by the Viridian 30-day money back guarantee
Attaches to virtually any railed gun
Technical Information
Battery Type: CR2 3V Lithium
Battery Life: 4+ hours (constant), 7+ hours (pulse mode), 1+ hours (Laser & Light)
Light Output: 100 Lumen
Laser Output: 5mW Laser
Laser Range: 100 yds (Daylight), 2 Miles (Night)
Holster Fit: Springfield XD/XDM
Warranty: 1-year factory warranty
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Frank Darabont
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Birth Name: Frank Darabont
Born: 01/28/1959
Birth Place: France
Born: 01/28/1959
Birth Place: France
Born in a refugee camp in Montbeliard, France on Jan. 28, 1956, he was the son of Hungarian parents who had fled the country after the failed revolution that year. The family immigrated to the United States when Darabont was a child, and eventually settled in Los Angeles shortly before he entered high school. After attending Hollywood High, he began working in the film industry as a production assistant and set dresser; his first screen credit was the 1981 slasher film "Hell Night," and he worked steadily in the horror and fantasy genre - his favorite - for the next few years.
However, Darabont's career as a filmmaker began a year earlier, when he sent an ambitious letter to best-selling h... Continue Bio >>
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The Great Debate (India)
from The Great Debate UK:
Pranab Bardhan on the economic rise of China and India
In its May economic outlook, the Organisation of Economic Cooperation and Development projected upward growth outlooks for BRIC countries Brazil, Russia, India and China -- the world's four largest emerging economies.
Strong growth in those economies is helping to pull other countries out of recession, the OECD said. The Paris-based organisation projects that China's GDP growth will exceed 11 percent for 2010, and anticipates that India's real GDP growth will be 8.3 percent. Russia's GDP growth is expected to be 5.5 percent, and Brazil's is projected at 6.5 percent. By comparison, the OECD projects that the Euro area will see 1.5 percent real GDP growth, while the UK will see a 2.2 percent growth.
The "BRIC" acronym was created by Goldman Sachs economist Jim O'Neill in 2001 to mark a shift of economic power from the West. In June 2009, the BRIC leaders met in Yekaterinburg, Russia, for a summit, which was seen as the beginning of a geopolitical alliance, although their economies are very different: Brazil's economy is based on agriculture; Russia's on energy exports; India's on services and China's on manufacturing. At that time, the BRIC countries accounted for 40 percent of the world's population and about 15 percent of its economy.
In a new book titled "Awakening Giants, Feet of Clay: Assessing the Economic rise of China and India", Pranab Bardhan, a professor of economics at the University of California, Berkeley, dissects some generally accepted beliefs about the economies of China and India -- arguing that they are oversimplified -- to provide a new perspective on what to expect from the two countries in the future.
from The Great Debate UK:
Vikas Pota on ten business icons in India
Amid jitters about uncertainty in the financial markets over the past 16 months, many investors have continued to look toward the BRIC countries -- Brazil, Russia, India and China, which by 2050 are expected to be wealthier than most current major economic powers.
In all four countries, GDP has more than doubled since 1998, and in China and India it has trebled.
from Global Investing:
Time to kick Russia out of the BRICs?
It may end up sounding like a famous ball-point pen maker, but an argument is being made that Goldman Sach's famous marketing device, the BRICs, should really be the BICs. Does Russia really deserve to be a BRIC, asks Anders Åslund, senior fellow at the Peterson Institute for International Economics, in an article for Foreign Policy.
Åslund, who is also co-author with Andrew Kuchins of "The Russian Balance Sheet", reckons the Russia of Putin and Medvedev is just not worthy of inclusion alongside Brazil, India and China in the list of blue-chip economic powerhouses. He writes:


text:
AAIC Press Release
<< See all AAIC Press Releases
Contact: Alzheimer's Association® | Media line: 312.335.4078 | E-mail: email@example.com |
AAIC 2013 press room, July 13-18: 617.954.3414
Additional Results from Phase 3 Trial of IVIG in Alzheimer's Reported at Alzheimer's Association International Conference
BOSTON, July 16, 2013 – Additional analyses from a negative Phase 3 clinical trial of IVIG (intravenous immunoglobulin) in people with mild to moderate Alzheimer's disease were reported today at the Alzheimer's Association International Conference® 2013 (AAIC® 2013) in Boston.
"We learn more about Alzheimer's disease from every study," said Maria Carrillo, Ph.D., Alzheimer's Association vice president of Medical and Scientific Relations. "Even negative trials provide critical information to the research community for application in future studies to help us find better treatments, which are so desperately needed."
In May 2013, Baxter International announced topline results of the first Phase 3 clinical trial of IVIG as an add-on to established therapy in people with mild to moderate Alzheimer's disease, known as the Gammaglobulin Alzheimer's Partnership (GAP) Study. The drug did not meet either of its primary endpoints.
"These results show us exactly why drugs, in particular those that are approved for one disease that are being tested for another, must go through the very thorough FDA approval process," said Mary Sano, Ph.D., Director of the Alzheimer's Disease Research Center at Mount Sinai School of Medicine, Bronx, NY, and a member of the executive committee for the GAP Study. "The FDA process protects people from misguidedly using drugs that are not effective and may be very costly."
Dr. Sano is a member of the Alzheimer's Association Medical and Scientific Advisory Council.
Updated Results from the GAP Phase 3 Trial of IVIG in Mild to Moderate Alzheimer's
In their topline announcement in May 2013, the GAP Study researchers reported that the results were negative on the main outcome measures, which were two well-established tests of cognition and daily functioning – the ADAS-Cog and ADCS-ADL. At the same time, they reported favorable cognitive changes in two pre-specified subgroups: people with Alzheimer's who carried the APOE-e4 Alzheimer's risk gene and those who were moderately impaired. According to the data presentation, the study was not powered to show statistical significance in the subgroups.
At AAIC 2013, Norman Relkin, M.D., Ph.D., of Weill Cornell Medical College and the Cornell Memory Disorders Program, and lead investigator of the GAP study, reported for the first time on additional analyses, including cognitive and biomarker tests. For cognition, the researchers found that study participants in the APOE-e4 carrier subgroup receiving IVIG 400mg/kg/2wk (n=87) had numerically superior results at 18 months relative to placebo on the Modified Mini-Mental State (3MS) Examination (n=66) and the Trails B test (n=77), two out of several measures of thinking ability made in the study.
"Though 3MS and Trails B were not the primary outcome measures in the study, they are well-established cognitive measures and, therefore, may suggest other ways to measure change in future Alzheimer's disease clinical trials," Relkin said.
Biomarker analyses demonstrated that antibodies from the treatment reached the central nervous system. The researchers found:
- A statistically significant, dose dependent reductions in plasma beta-amyloid 42 levels (but not beta-amyloid 40) was observed in IVIG treated patients relative to placebo.
- Statistically significant, dose dependent increases in anti-oligomer and anti-fibril antibodies in the CSF or plasma occurred in IVIG-treated patients relative to placebo.
- A reduction in brain fibrillar amyloid (as measured by PET scan using florbetapir) was seen in patients who received IVIG at the 400mg/kg/2wk dose.
- No effect in tau and phosphorylated tau levels in spinal fluid.
"It is important to say that the GAP study results do not provide grounds for prescribing IVIG in Alzheimer's disease, even with this positive signal in the APOE-e4 carriers, further confirmatory studies would be needed before clinical use could be recommended," Relkin said.
"The primary clinical outcomes are unequivocally negative, but there are signals in the clinical and biological markers in some subgroups. With the understanding that we cannot draw conclusions about IGIV's effectiveness in these subgroups from these results alone, the effects of IVIG on beta-amyloid and antibody levels in the blood and brain are noteworthy. These results support that IVIG can target beta amyloid and that the antibodies it contains can reach the brains of people with Alzheimer's when administered through the bloodstream."
"Research should continue in people with mild to moderate Alzheimer's; the field should not focus exclusively on early intervention strategies," said Relkin.
The Gammaglobulin Alzheimer's Partnership (GAP) Study was a Phase III, randomized, double-blind, placebo-controlled clinical trial in 390 people with mild to moderate Alzheimer's disease, conducted at 45 centers in the U.S. and Canada. Two different doses of IVIG were tested versus placebo as add-ons to approved Alzheimer's medications. The drug was administered every two weeks for 18 months. Primary study endpoints were changes on two well-established tests of cognition and daily functioning – the ADAS-Cog and ADCS-ADL. The GAP study was conducted by Baxter and the Alzheimer's Disease Cooperative Study, a clinical trial consortium supported by the National Institute on Aging at the National Institutes of Health. Baxter studies of IVIG in mild to moderate Alzheimer's disease were discontinued after the announcement of topline results in May.
APOE-e4 is one of three naturally occurring forms of the APOE gene; the others are APOE-e2 and APOE-e3. Everyone inherits a copy of some form of APOE from each parent. Those who inherit one copy of APOE-e4 have an increased risk of developing Alzheimer's disease. Those who inherit two copies have an even higher risk, but not a certainty. Risk genes increase the likelihood of developing a disease, but do not guarantee it will happen. Researchers have found several genes that increase the risk of Alzheimer's. APOE-e4 is the first Alzheimer's risk gene identified, and remains the gene with strongest impact on risk.
Despite the negative results of the Phase 3 IVIG trial, and because of the successes of IVIG in animal models of Alzheimer's and early stage trials in people, researchers continue to pursue how IVIG may work in the brain to inform ongoing Alzheimer's therapy research.
IVIG reduces tau pathology in a mouse model of Alzheimer's disease
"IVIG may help clear brain amyloid to prevent amyloid plaque buildup, but the poor results so far of clinical trials targeting amyloid raise the possibility that IVIG acts in a different way. Therefore, we tested whether IVIG might target the other characteristic lesion of the Alzheimer's brain, the neurofibrillary tangle," said Scott Counts, Ph.D., of Rush University Medical Center, Chicago.
Counts and colleagues at Rush tested whether IVIG alters the expression of tau tangle-like deposits in the brains of a transgenic mouse model of Alzheimer's that displays tangles as it ages. Three month old mice were treated intravenously with either IVIG or saline every two weeks for either three months or six months. The brains of these mice were then examined to see if IVIG reduced tangle build-up.
- The researchers found that the IVIG-treated mice experienced a small (roughly 15%) but statistically significant decrease of tangle pathology in brain cells of the hippocampus, a brain area that controls memory, compared to saline-treated mice (p < 0.01, n=10/group).
- They also analyzed the blood plasma of the mice to explore whether IVIG altered genetic markers that reflect brain protection. They found that IVIG treatment resulted in a 40 to 50% increase in plasma levels of several genes that are involved in maintaining proper neuronal function.
"Our preliminary data suggest that IVIG may reduce Alzheimer's-like tangle pathology and increase neuroprotective gene expression in a mouse model of Alzheimer's disease," Counts said.
IVIG may make neurons less vulnerable to damage from reactive oxygen species
In an effort to uncover the mechanism(s) by which IVIG might provide benefit, Debomoy Lahiri, Ph.D., of the Indiana University School of Medicine, and colleagues recently showed that treatment of degenerating rat brain cells with IVIG in a test tube protected the structure of the cells and enabled them to survive longer. They hypothesized that IVIG treatment might also preserve and protect human brain cells.
Lahiri and colleagues created primary human fetal brain neuron (HFN) cultures and treated them with several different doses (5-20mg/ml) of IVIG for 72 hours. The cell cultures were then exposed to reactive oxygen species (ROS) for 24 hours. Separate HFN cultures were treated with different doses of IVIG (5-20mg/ml) but not exposed to ROS.
Reactive oxygen species (ROS) are molecules that form as a natural byproduct of the normal metabolism of oxygen; they have important roles in communication between cells and keeping the body's internal environment stable (homeostasis). However, during times of environmental stress, ROS levels can increase dramatically. This can cause significant damage to cells; it is known as oxidative stress.
The scientists observed that IVIG pre-treatment (10 and 20mg/ml) provided significant protection to brain cells that were subsequently exposed to ROS. They also observed significant increase in cell viability in the neurons when they were treated with 10 and 20mg/ml doses of IVIG alone for four days.
"Our results suggest that IVIG treatments may make neurons less vulnerable to damage from reactive oxygen species," Lahiri said. "Since preventing brain cell loss in Alzheimer's is an important goal of therapy, our results suggest that IVIG may be beneficial for preserving and protecting neurons against oxidative damage."
"This is particularly important because we know that beta amyloid deposits in the Alzheimer's brain indirectly lead to the generation of ROS, including free radicals, that damage and destroy brain cells," Lahiri added.
About AAIC
The Alzheimer's Association International Conference (AAIC) is the world's largest conference of its kind, bringing together researchers from around the world to report and discuss groundbreaking research and information on the cause, diagnosis, treatment and prevention of Alzheimer's disease and related disorders. As a part of the Alzheimer's Association's research program, AAIC serves as a catalyst for generating new knowledge about dementia and fostering a vital, collegial research community.
About the Alzheimer's Association
The Alzheimer's Association is the world's leading voluntary health organization in Alzheimer care, support and research. Our mission is to eliminate Alzheimer's disease through the advancement of research, to provide and enhance care and support for all affected, and to reduce the risk of dementia through the promotion of brain health. Our vision is a world without Alzheimer's. Visit www.alz.org or call 800-272-3900.
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- Norman Relkin, et al. Results of the GAP 160701 Study: A Phase 3 Clinical Trial of Intravenous Immunoglobulin for Mild to Moderate Alzheimer's Disease - Norman Relkin on Behalf of the ADCS and Baxter GAP 160701 Study Group (Funders: Baxter; U.S. National Institute on Aging)
- Scott Counts, et al. IVIG reduces tau pathology and increases neuroplastic gene expression in the 3xTg mouse model of Alzheimer's disease. (Funder: Baxter)
- Debomoy Lahiri, et al. Effect of IVIg in Preserving Human Primary Neurons & Protecting Them Against Oxidative Stress. (Funder: Baxter)
Proposal ID: 39689
Topic: Therapeutics Subtopic: Clinical Trials
Presentation: Oral session, Tuesday, July 16, 2013, 2:15 pm ET
Results of the GAP 160701 Study: A Phase 3 Clinical Trial of Intravenous Immunoglobulin for Mild to Moderate Alzheimer's Disease - Norman Relkin on Behalf of the ADCS and Baxter Gap 160701 Study Group
Presenting Author: Norman Relkin (firstname.lastname@example.com), Weill Cornell Medical College and the Cornell Memory Disorders Program.
Background: The Gammaglobulin Alzheimer's Partnership (GAP) 160701 Study is a pivotal Phase 3 clinical trial testing the safety and efficacy of Gammagard® IGIV for the treatment of mild to moderate Alzheimer's disease (AD). This presentation provides the final outcomes of the GAP trial.
Methods: All subjects met NINDS-ADRDA criteria for Probable AD (MMSE 16-26 inclusive). Subjects and their study partners consented to participate in the IRB approved protocol. Subjects were randomly assigned to receive intravenous infusions of IGIV 10% at a dose of 0.4 grams/kilogram/2 weeks or 0.2 grams/kilogram/2 weeks or a low dose albumin placebo. The study medication was administered for 18 months (36 infusions) as an add-on to conventional FDA-approved AD medications. Randomization was balanced for baseline MMSE score and APOE genotype. All subjects underwent clinical outcome and safety assessments as well as serial plasma collection and neuroimaging with MRI. Subsets of participants consented to sub-studies involving collection of CSF, FDG PET or AV-45 PET. The co-primary outcomes were the 18 month change from baseline on the ADAS-Cog and ADCS-ADL. The primary analysis was performed on the Intent-to-Treat cohort. In addition, a completer analysis was performed that included all randomized subjects who completed at least 90% of planned infusions.
Results: A total of 732 persons were screened. 390 persons meeting NINDS-ADRDA criteria for Probable Alzheimer's Disease were randomized. 279 subjects (72.3%) completed 18 months of treatment. An additional 22 subjects (5.1%) discontinued study medication before 18 months but completed evaluation visits through month 18. The remaining 88 subjects (22.6%) discontinued study medication and evaluation visits prior to 18 months. Mean age of the study participants was 70.3 years (range 50-89), including 213 females and 177 males. The mean baseline MMSE score was 21.3. At time of enrollment, 381 subjects were receiving cholinesterase inhibitors and 283 were taking memantine. More than 14000 infusions were provided to subjects collectively over the course of the study. The last study visit was completed in December 2012.
Conclusions: Final study outcomes will be presented at the AAIC meeting.
Proposal ID: 37653
Topic: Basic Translational Science Subtopic: Molecular and cell biology
Presentation: Poster session, Monday, July 15, 2013, 11:45 am ET
IVIG reduces tau pathology and increases neuroplastic gene expression in the 3xTg mouse model of Alzheimer's disease
Presenting Author: Scott Counts (firstname.lastname@example.com)
Scott Counts, Sylvia Perez, Elliott Mufson, Rush University Medical Center, Chicago, Illinois, United States.
Background: Current FDA-approved treatments for Alzheimer's disease (AD) offer short-term clinical benefits but fail to alter disease progression. Phase III trials testing the efficacy of Abeta immunotherapy have not improved cognition in people with mild AD. More recently, intravenous immunoglobulin (IVIG) treatment has emerged as an alternative AD immunotherapy. In this regard, placebo-controlled, double blind phase II clinical trials with IVIG demonstrated good tolerability and improved cognitive outcomes in patients with mild/moderate AD. However, the mechanisms underlying the effect of IVIG upon cognitive outcomes remain unknown. IVIG contains antibodies to Abeta causing a shift of Abeta protein concentration from the cerebrospinal fluid to blood, suggesting a brain amyloid clearance mechanism. However, the suboptimal results of clinical trials of anti-amyloid monoclonal antibodies raise the possibility that IVIG acts via an amyloid-independent mechanism.
Methods: We tested whether IVIG alters the expression of tau neurofibrillary tangle (NFT)-like deposits within hippocampal CA1 neurons of the 3xTg mouse model of AD. Three month old mice were treated intravenously with either IVIG (10%, 400 mg/kg) or saline every two weeks for either three months or six months. At sacrifice, blood was drawn for plasma gene expression profiling and brains processed for immunohistochemistry using the AT-180 antibody, which recognizes the T231 tau phosphorylation event involved in NFT formation.
Results: Preliminary quantitative densitometric analysis of CA1 neurons following three months of treatment revealed a small but significant ~15% decrease in AT-180 immunoreactivity with IVIG compared to saline-treated 3xTg mice (p < 0.01, n = 10/group). Expression profiling studies showed that IVIG treatment resulted in a 40-50% increase in plasma levels of several modulators of neuronal plasticity, including synaptophysin, homer-1, nestin, and neurofilament-H (p < 0.05, n = 6/group).
Conclusions: Preliminary data suggest that IVIG reduces hippocampal NFT pathology and up-regulates neuroplastic gene expression in the 3xTg mouse model of AD.
Proposal ID: 39290
Topic: Therapeutics Subtopic: Others; Neurogenesis
Presentation: Poster session, Wednesday, July 17, 2013, 11:45 am ET
Effect of IVIg in Preserving Human Primary Neurons & Protecting Them Against Oxidative Stress
Presenting Author: Debomoy Lahiri (email@example.com)
Debomoy Lahiri, Balmiki Ray, Indiana University School of Medicine, Indianapolis, Indiana, United States
Background: Neurons in Alzheimer's disease are more vulnerable to toxic stimuli, including reactive oxygen species (ROS). A promising treatment strategy for AD is to preserve and protect neuronal cells from oxidative damage. We have recently shown that treatment with intravenous immunoglobulin (IVIg) protects neuronal viability and synaptic proteins in degenerating primary rat hippocampal neurons. We hypothesized that IVIg treatment would preserve, protect and increase human neurons. Here, we report a potent neuropreservatory effect of IVIg against ROS-mediated neuronal damage in primary human fetal brain neuron (HFN) cultures.
Methods: HFNs were cultured (Long et al., JBC-2012) and treated with different doses (5-20mg/ml) of IVIg (Gammagard, Baxter) for 72 h. Glycine and Buminate (Baxter) were added to the cultures separately as vehicle and placebo, respectively. Following IVIg treatments, media were removed, and fresh media with 50µM H2O2 (ROS), without the addition of IVIg, was added into the wells. Cells were harvested after 24 h of ROS exposure, and morphology recorded by imaging and immunocytochemistry (ICC). Separately, HFN cultures were treated with different doses of IVIG (5-20mg/ml) along with the vehicle and placebo. Effects of IVIg alone on neurons were assessed by cellular viability assay (CTG), and on cellular morphology/neurite lengths by ICC.
Results: We succeeded in growing viable HFN cultures from the human fetal brain as assessed by ICC. We observed that IVIg (10 and 20mg/ml) pre-treatment provides significant protection to neurons subsequently challenged with ROS. We also observed significant increase in cell viability in the neurons when they were independently treated with 10 and 20mg/ml doses of IVIg for four days, suggesting increased metabolic activity of exiting neurons or increased neuronal mass.
Conclusion: IVIg treatments make neurons less vulnerable to ROS-mediated damage. Pre-treatment with IVIg alone protected neurons when they were post-treated with ROS. We also observed increased viability of neurons following IVIg treatments. IVIg increases metabolic activity and perhaps the number of viable neurons. Since preventing neuronal loss in AD is an important goal to obtain therapeutic efficacy, our results suggest that IVIg is beneficial for preserving and protecting neurons against oxidative insult and for its effect on increased neuronal viability.
(Acknowledgments: We sincerely thank Dr. Michelle Gilmor for her advice and Nipun Chopra for technical help, and Baxter for research support.)
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AAIC 2013 program
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