Phage Display is a powerful tool for identification of protein ligands against a myriad of targets. In our study, we selected a small protein member from the Kunitz family to serve as a scaffold in the MIII 13 phage coat protein. The protein, originally a scorpion toxin that inhibits a potassium‐dependent voltage channel, has 33 residues composed of two beta sheets and an alpha helix stabilized by disulfide bonds. After cloning the toxin gene into an M13 phagemid, we used Kunkel's mutagenesis, an additional uracil‐DNA glycosylase treatment, and rolling circle amplification (RCA) procedures to produce a synthetic Kunitz‐type phage display library. We drove the mutations in specific residues within two specific loops as well as within the alpha helix of the scaffold protein, keeping the cysteines intact. We were able to produce a library of over a million different proteins. To validate the ability of this library to bind specific targets, trypsin was used as target. Since other studies have proved Kunitz's natural proteins as protease inhibitors, we expect our displayed Phage protein library to generate new potent and specific protease inhibitors for medical as well as biotechnological purposes.


The present invention provides a wireless power transmission system and a control method thermal stability is excellent. The system comprises a transmitting coil frequency generator and coil frequency phase tracking feedback unit. Transmitting coil frequency generator control circuit, made from the drive circuit and an inverter circuit, a coil frequency phase tracking feedback section is composed of the frequency detection circuit and a phase locked loop circuit. Wherein the control circuit is controlled by the software to output the exact opposite of the control signals of two channels, through the drive circuit controls one channel switch on and off, respectively, to generate a high-frequency vibrations in the coil the features. The control for the software system, the components themselves parameters reduces drift problems frequency points by environmental temperature parameter, and precise control of frequency points and AC frequency characteristic of the wireless power transmission circuit, the heating problem of the critical components reduced, improving the power transmission efficiency of the wireless power transmission circuit.


Based on the review of environmental archaeology at the Yangtze-Huaihe Basin in Anhui,the regional environmental archaeological research achievements were summarized in recent years.At the same time,the regional environmental archaeological research means and methods were hackled,the main problems about environmental archaeological studies were pointed out at the Yangtze-Huaihe Basin in Anhui,and the next research methods were proposed,which through interdisciplinary,multiple measures on natural sedimentary strata and archaeological strata with environmental proxy indicators to implement the integrated research on environmental archaeology in this area.(1) to establish the high-resolution chronological framework and environmental evolution sequence;(2) through the typical Neolithic ruins to establish the regional archaeological cultures sequence;(3) to establish flood catastrophe stratigraphic markers and to extract the flood catastrophe events information from stratum;(4) to explore the human activities how response to the regional environmental evolution.The study will lay the foundation to the trajectory of ancient civilizations origin and development,furthermore,it will reveal the influence mechanism on man-land relationship with the regional environmental evolution and the Paleoflood catastrophe events at the Yangtze-Huaihe River Basin in Anhui.


We propose a new Bayesian approach to object-based image retrieval with relevance feedback. Although estimating the object posterior probability density from few examples seems infeasible, we are able to approximate this density by exploiting statistics of the image database domain. Unlike previous approaches that assume an arbitrary distribution for the unconditional density of the feature vector (the density of the features taken over the entire image domain), we learn both the structure and the parameters of this density. These density estimates enable us to construct a Bayesian classifier. Using this Bayesian classifier, we perform a windowed scan over images for objects of interest and employ the user's feedback on the search results to train a second classifier that focuses on eliminating difficult false positives. We have incorporated this algorithm into an object-based image retrieval system. We demonstrate the effectiveness of our approach with experiments using a set of categories from the Corel database.


The role of an advocate as a free and independent law enforcement is guaranteed by law and legislation to be very important in the law enforcement process. Through legal services provided by both paying and underprivileged clients is the same in terms of treatment but in reality it is still rarely advocate to provide legal aid to the community is not capable, especially in civil disputes How the implementation of advoiat in providing legal assistance free of charge only to the community is not capable in particular in sengkete keperdataan. What factors are the obstacles of advocates in providing legal aid only to the community is not able especially in civil disputes? This study uses the method of Juridical Sociological Approach, with the location of research at the Office of Legal Aid Institute of Malang City Type of data used is the primary data obtained from the field and secondary data from legislation, primary data collection techniques obtained from interviews and secondary data obtained through library studies and tracing legislation. Analyzed using qualitative descriptive techniques. Based on research obtained from 5 resource persons at Advocate Office of Legal Aid Institute of Malang City, as for the result of research that still lack of handling done by Legal Aid Institution in giving legal aid free of charge to society is not capable especially keperdeataan and there are 6 factoryamg influence one of them is lack socialization from advocates to the community.


We introduce a multiuser detection algorithm for Direct Sequence Code Division Multiple Access (DS-CDMA) systems that implements a fast relative newton algorithm in a quasi-maximum likelihood (quasi-ML) estimation framework. The symbol signals are estimated based on this quasi-ML criteria at reduced Bit-Error-Rate (BER) and reduced computational load. Specifically, we construct multiuser detectors based on this new algorithm as well as the leading RobustICA and FastICA algorithms. Then, we demonstrate the significant improvements in Bit error rate (BER) and computational speed achieved by this new algorithm in comparative simulation studies.


The VA has made progress in implementing mandates to expand medical residency programs to more rural and underserved locations and to increase access to family care providers, but some specialties, like geriatrics, remain underrepresented.


INTRODUCTION................................................................ 455 THE EARLY PERIOD ................. .......................................... 456 Antiquity of the Disease......................................................... 456 Smallpox During the Middle Ages................................................ 458 Smallpox During the Seventeenth and Eighteenth Centuries.......................... 458 INTRODUCTION OF VARIOLATION INTO BRITAIN AND COLONIAL AMERICA ... 458 Variolation in Asia and Africa ................................................... 458 Role of the Royal Society of London .............................................. 459 Role of Lady Mary Wortley Montagu............................................. 460 Endorsement and Practice of Variolation in Britain................................. 463 Role of the Reverend Cotton Mather in Colonial America ...... ..................... 464 Variolation in Continental Europe and Colonial America ............................ 466 JENNER SUBSTITUTES VACCINATION FOR VARIOLATION ...................... 466 Edward Jenner and his Innovation .......... ..................................... 466 Jenner's Opponents and Supporters ......... ..................................... 471 Initiation of Vaccination Programs in Europe and Worldwide Acclaim of Jenner's Innovation .............................................................. 476 Eastward and Westward Odysseys of Vaccination ....... ........................... 477 Role of Benjamin Waterhouse and James Smith in the Introduction of Vaccination to the United States ............................................................ 479 SMALLPOX AFTER THE JENNERIAN INNOVATION.............................. 482 Worldwide Prevalence .......................................................... 482 The Disease................................................................... 482 Recent Importations of Smallpox to the United States and Europe .................... 486 Laboratory-Associated Infection in London........................................ 488 Vaccines and Method of Inoculation .............................................. 488 Discontinuation of Vaccination in the United States................................. 489 Adverse Reactions to Vaccination .......... ...................................... 489 GLOBAL ERADICATION OF SMALLPOX ........ ................................ 490 Concept of Eradicating Smallpox................................................. 490 Preparations for Global Eradication .............................................. 490 Problems and Setbacks ............... .......................................... 492 The 10-Year Program for Global Eradication ...................................... 494 Phase I..................................................................... 494 Phase II .................................................................... 495 Phase III.................................................................... 496 Certification of Global Eradication .......... ..................................... 498 Use of Vaccine After the Global Eradication ....................................... 500 POXVIRUS DISEASE AFTER THE GLOBAL ERADICATION OF SMALLPOX........ 501 Laboratory-Associated Infection at Birmingham University ...... .................... 501 Human Infections with Animal Poxviruses......................................... 503 Monkeypox virus ............. ............................................... 503 Whitepox viruses............................................................. 505 Other animal poxviruses ............. ......................................... 505 Smallpox Scares ............... ................................................ 506 Certain Unanswered Questions................................................... 507 ACKNOWLEDGMENTS ......................................................... 507 LITERATURE CITED .......................................................... 507


The formulation, manufacture and testing of an epoxy resin‐based solid substitute for water is presented. This ''solid water'' has radiation characteristics very close volumetrically to those of water. When it is used as a dosimetry phantom for x‐ and γ‐ray beams in the radiotherapy range, phantom‐to‐water corrections and density corrections are eliminated. Relative transmission measurements have shown that the transmission through 10 cm of solid water is within 0.2% of that through an equal thickness of water for x and γ rays. The use of this material for calibration phantoms can help achieve the goal of radiotherapy beam calibrations within ±1.0% of the true dose rate, easier to achieve.


Extreme metal music demands, and expects, extreme skills from producers and engineers. In this in-depth masterclass we explain the
techniques that go into crafting modern metal sounds.


A new technique for multistep phase‐contrast image processing is presented. The N‐step method consists of simply forming the linear average of the N — 1 adjacent phase‐difference signals. It has similar noise reduction properties as other multistep techniques, but the simplicity of the noise variance of the N‐step technique allows intuitive insight into phase‐difference phase‐contrast processing and noise reduction, which can aid in the design of efficient and improved phase‐contrast imaging sequences. As well, the computational simplicity of the N‐step phase‐difference technique compared with any other known multistep technique is advantageous. Like other multistep techniques, it has far more efficient noise reduction properties than simple two‐step, multiple average phase‐contrast imaging, even when normalized for total scan time. A three‐step phase‐difference velocity image has 50% less variance than an image acquired with two steps and two scans averaged but is obtained in 25% less scan time. Given its advantages, it should now be the chosen technique for increasing velocity‐to‐noise and contrast‐to‐noise ratios in all phase‐difference phase‐contrast clinical applications.


Census 2000 procedures were rehearsed in three sites during 1998: Sacramento, California; Menominee county, Wisconsin, including the Menominee Indian Reservation; and Columbia, South Carolina with eleven surrounding counties. These sites provided responses to the initial census as well as to an independent second enumeration, the Integrated Coverage Measurement (ICM) survey, of sampled areas in these sites. (In South Carolina, the coverage measurement survey was designed as an evaluation not strictly integrated with the census. Yet, to simplify descriptions, this paper refers to all 1998 coverage measurement as ICM.) The ICM involves two samples. Both are based on housing units found in blocks (or subsampled sections of large blocks) selected from census sites. The E-sample is comprised of persons reported in the census as Census Day residents in those housing units; it is used to count errors among those the census did count. The P-sample includes persons the survey found residing in housing units in the same areas on Census Day; it is used to determine who was missed in the census. Names of persons in the P-sample of the ICM are sought among census names. Persons found in both are matches. The focus of this paper is on P-sample nonmatches, persons who were not found to be enumerated in the Census 2000 Dress Rehearsal. The aim is to identify characteristics that may be related to their being missed in census enumeration. The statistic used in this study is the nonmatch rate, the proportion of nonmatches among Psample persons, computed within age, race, and other descriptive categories. The nonmatch rate is well related to (but less refined and more inflated than) the dual system adjustment factor used in census coverage evaluation. Errors and incomplete data estimated from the E-sample, as well as matches that may exist among census enumerations beyond areas searched, are refinements taken into account by dual system estimates but not nonmatch rates. Nonmatch rates are worthy of study independent of the effects of false or ambiguous enumerations, which are investigated by Feldpausch and Childers (1999) and by Jones and Childers (1999). Beaghen (1999) modeled both E-sample and P-sample data to gain insight into misses. Several prior publications provide more background for this research. The procedures for both census and survey data collections in the Census 2000 Dress Rehearsal are described in Waite and Hogan (1998). Childers (1999) describes the ICM more completely. P-sample nonmatches were analyzed in the context of the 1990 census results by Moriarity and Childers (1993) using some of the same variables investigated in this research.


In 1963 Rubinstein and Taybi described, in seven children, a new symptom-complex characterized by broad thumbs and great toes, facial abnormalities, mental retardation and a cluster of congenital mal¬ formations. Since then 14 additional cases have been reported. In this paper three more such children are described. Chromosome studies were normal. The etiology of this disorder is unknown but it is probably genetic. enfants. cariotypes Etaient maux. ce trouble n'est pas elucide, mais d'origine g£n&ique.


A geological feature in the Qaidam Basin known as the'Shell Bar'contains millions of freshwater articulated clam shells buried in-situ.Since the 1980s this feature in the now hyper-arid basin has been interpreted to be lake deposits that provide evidence for a warmer and more humid climate than present during late Marine Isotope Stage 3(MIS 3)(Bowler et al.,1986).However,the global climate during


In the current era of automation, vehicle automation plays a vital role in the current technological evolution. Vehicle automation and detection mechanisms are attracting so many research enthusiasts in this period. This research work has utilized this opportunity to play our role by creating our project for Surveillance-Based Spotting and Categorization of Automobiles. The main focus of our project lies in the detection and categorization of vehicles that are in motion and in still positions. Though there are numerous methods of vehicle detection using sensors, microchips, and many other technologies, all of these tend to be vulnerable to environmental factors that affect their longevity and increase the cost of their implementation as well as their maintenance. To avoid these additional costs, a computer vision technology that uses a vision-based detection mechanism is used to detect the vehicles from the real-time video input with the help of image fragmentation and pattern recognition. The goal of this project is to provide a feasible and cost-effective system to spot and categorize various kinds of automobiles using OpenCV and YOLOv3.


At present,"the twelfth five-year plan" emphasizes on establishing harmonious society and service-type government,which provides requirement and opportunity for the development program of public administration discipline of IMUFE.Using IFE and EFE environmental analysis matrix as basic research methods,this paper analyzes the internal and external environment of public administration discipline of IMUFE,makes clear the developing opportunity and challenge in expectation to provide certain theoretical basis for the establishment of development objectives and policy-making.


IN THIS PAPER,BASIC THEORY AND FUNDAMENTAL STRUCTURE OF MACHINE VISION IS ILLUSTRATED,AND ITS APPLICATION IN AUTOSORT SYSTEM OF SHEET IS GIVEN,ALSO SHOWS IMPORTANT EFFECTION OF AREA CCD IN MACHINE VISION SYSTEM OF AUTOSORT SYSTEM OF SHEET.


Accurate genetic diagnosis in inherited muscle diseases is challenging, with over 30 causative genes for the limb-girdle muscular dystrophies (LGMDs) alone,1 but also vital, with gene-specific therapies now available and more on the horizon.2 Although next-generation sequencing provides a wealth of genetic data, interpretation often requires deep phenotyping including clinical, laboratory, and imaging data. Many MRI studies have described the different patterns of muscle involvement in inherited muscle diseases.3 Whereas the MRI patterns are generally concordant with the clinical distribution of weakness, using MRI patterns of involvement potentially offers greater complexity and discrimination because of the ability to assess each muscle individually.


Since the coming to power of the present administration in Nigeria on 29 th May, 2015, salaries of civil servants in not less than twenty-seven out of thirty-six States of the country and the Federal Government are in arrears for several months. The state governments that have failed and/or refused to pay workers' salaries have gone cap in hand asking for bailout funds from the Federal Government to no avail. In the alternative, some have opted to down size the workforce or even embark on downward review of the national minimum wage payable to workers.In this article, we canvassed that, the failure of the Governors and the Federal Government of Nigeria to pay workers' salaries had occasioned severe deprivation, mental and physical health challenges to most Nigerian civil servants and indeed any worker at that. This situation has reduced the lives of the workers in their employ to a bare life, or life not worth living, thus taking away their human dignity, due to their failure to pay the workers their salaries.These are human rights abuse. As a general rule, the duty to pay workers' salaries and wages is derived from the terms of the contract of service expressly or impliedly or by statute. This duty which is implied at common law is applicable to every contract of employment. It is protected in Part I sections 15 and 17 of the Nigeria Labour Act and equally entrenched in various international human rights instruments to which Nigeria is a signatory. Keywords : contract of service, non-payment of salaries, human right abuse, Nigeria constitution.


Twisted Calabi-Yau algebras are a generalisation of Ginzburg's notion of Calabi-Yau algebras. Such algebras A come equipped with a modular automorphism σ ∈ Aut(A), the case σ = id being precisely the original class of Calabi-Yau algebras. The aim of this paper is to give a concise proof of the fact that every twisted Calabi-Yau algebra may be extended to a Calabi-Yau algebra. More precisely, we show that if A is a twisted Calabi-Yau algebra with modular automorphism σ, then the smash product algebras Aoσ N and A oσ Z are Calabi-Yau.


Abstract Since the publication in 1895 of George Wiebe's work, Zur Geschichte der Preisreuolution des XVI. und XVII. Jahrhunderts, 1 the 'price revolution' has been a generally accepted concept found in most historical textbooks. By the 'price revolution', Wiebe meant the general rise in commodity prices which occurred in western Europe during the 16th century, the primary cause of which according to him was the influx of silver from the new Spanish possessions in America. His explanation also came to be generally accepted, but perhaps an even more significant contribution to the influence which this book has wielded is the fact that he synthesized in readily usable form the price analyses in existence when he wrote, i.e. at the end of the 19th century. In the 1930s his tables still formed the basis of sweeping conclusions and generalizations.


The importance of culture and heritage is becoming more and more obvious, both in regionalists and regional development. Cultural factors are important because they directly affect economic performance and development, and therefore the competitiveness of the region. This study gives an overview of relevant literature, aiming to introduce the complex relations between culture, heritage, geography, tourism, economy and experience economy. Furthermore, it offers a clear definition of each specific term, and defines the newest forms and trends in cultural tourism and experience economy. © 2014 The Authors. Published by Elsevier Ltd. Selection and peer-review under responsibility of Institute of National Economy from Romanian Academy


In this paper, a novel speech emotion recognition scheme bases on intuitionistic fuzzy set (IFS) and discrimination information measures is proposed. Intuitionistic fuzzy set (IFS) is a new way of knowledge representation. In which, two character functions, the degree of membership (belongingness) and the degree of non-membership (non-belongingness), are adopted to describe the relation between the features and the patterns. The discrimination information is used to estimate the distance between the intuitionistic fuzzy sets in the paper. Finally, the experiment indicates that the method mentioned in this paper has a satisfying performance on the recognition of speech emotion.


Abstract : This paper examines the question of whether it is possible to substitute serial memory for conventional random access memory (RAMs) in commonly encountered numerical computations. There is much interest in tasks such as solving large systems of linear equations, large linear programming problems, and other calculations applied to large amounts of data concurrently with development of techniques for constructing large serial memories which are intrinsically less expensive than comparable RAMs. The answer to the question is 'yes' for those computations discussed in this paper if the serial memory is equipped with compare/exchange circuits so that it will sort its contents. Generally when using self-sorting memory, labels or keys are appended to the data to be stored; conventional machine addresses are not to be used. Data entries thus specified pass to simple arithmetic processors for the requisite numerical operations, after which the data may be returned to the self-sorting memory for retention until needed again. A property common to all computations discussed in this paper is the feasibility of computing the requisite memory output sequence as data is first passed to the memory, as well as in the course of computation. While there is clearly no analytic basis for asserting that the class of all common numerical computations shares this property, many computations not discussed in this paper are clearly within this class.


Complexation of HA (and FA) by goethite, hematite, gibbsite, and boehmite was studied in pre-dried systems. Hematite showed the highest fixation of HA at various oxide: HA ratios and at all pH ≥ 7.0. A gradual reduction in HA/FA fixation from 2.0 to 10.0 was observed for all minerals except gibbsite, which showed a very sharp decrease at pH > 7.0 and a maximum at pH 5.0. Exchangeable cations have a remarkably dissimilar influence on HA complexation by the four minerals. Thus, various cationic forms of gibbsite showed a drastic loss of HA fixation capacity compared with the original (pronated) surface, whereas in boehmite, the reverse behavior was observed. Most of the metal ion-substituted hematites showed excellent HA fixation, but goethites revealed a mixed trend. It is inferred that two major modes of HA bonding are operative in hematite and goethite, viz., cation bridges forming oxide-M-HA links and direct bonding of HA to coordination centers at the oxide surface; forces of such bonding are strongest in hematite. In boehmite, cation bridging is the major interactive mode, whereas in gibbsite, HA fixation occurs primarily to coordination centers at the surface.


With the Coalition's flagged rejection of the Clean Energy Target and former PM Tony Abbott's recent speech spreading climate denial myths, the media is once again talking about Australia's 'climate wars'.


This paper focuses on the characterization of shear behavior of RC beams strengthened with Near-Surface Mounted (NSM) GFRP bars. Based on ABAQUS, the finite element model for the shear behavior is established and the simulated results are compared with the test results. The parameters including spacing and inclination of GFRP bars, mechanical properties of the groove-filling epoxy, stirrup ratio and shear-span ratio of the specimen beams for the shear behavior are discussed. The simulated results show that there has a good agreement with the experiment results. The beams strengthened with NSM GFRP bars have a significant improvement in shear capacity. Further more, the analysis results on the parameters indicate that ultimate shear capacity of the beam strengthened with NSM-GFRP bars gradually increases with the decrease of spacing of GFRP bars. The ultimate bearing capacity increases of the strengthened beam with inclination of 45° is the more larger than those of 60° and 90°. The different types of epoxy adhesive and shear-span ratio have a great influence on the load-deflection curves of the strengthened beams.


The Oxygen Status Algorithm is a computer program which uses measurements from a pH & blood gas analyser and a haemoximeter to calculate the oxygen status and the acid‐base status of the arterial blood. Version 3 features on‐line data collection from the analyser; storage of up to 2000 patient cases in a Lotus 123 file format; printing of a Cumulated Patient Report in addition to the Patient Status Report; combination of arterial and mixed venous data for calculation of the shunt and the oxygen consumption rate (when cardiac output is keyed in); calculation of reference values for fetal haemoglobin for newborns (when gestational age is keyed in). Examples of applications answer the following questions:


The commenters point out that the idea using a two-dimensional digital correlation technique to perform synthetic-aperture-radar (SAR) processing, presented as new in the above-titled paper (see ibid., vol.24, p.218-23, May 1988), was described by them as early as 1978 and has since been described by other authors. They discuss some of these earlier studies. The author replies that he was unaware of the earlier work, and that he did not intend to convey the impression that the nonseparable transform domain processor that he presented was the first. >


The Inaugural Dinner of the Society was held after the meeting at Limmer's Hotel, Dr. Felix Semon presiding. Signor Manuel Garcia, the inventor of the laryngoscope, was present, and received an ovation as the first Honorary Member of the Society. Dr. McBride, Mr. Butlin, Mr. Victor Horsley, and the Chairman were the principal speakers, the proceedings being greatly enhanced by music and songs contributed by the Chairman, Dr. Dundas Grant, Dr. Jacob, and Dr. W. Aikin.


A linear-cavity externally modulated Er-doped fiber (EDF) laser that utilizes fibre Bragg gratings for cavity feedback and wavelength selectivity has been fabricated. The narrow linewidth and high repetition rate make it a valuable communication source.


Porous rGO/SiO2 nanocomposites with a "core-shell" structure were prepared as an efficient adsorbent for the liquid-phase adsorption of cationic neutral red (NR) dye. The samples were characterized with powder X-ray diffraction (XRD), field-emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), thermogravimetric analysis (TG), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, and N2 and water vapor adsorption/desorption methods. The NR removal ability and kinetics of the adsorption process of SiO2 and the rGO/SiO2 nanocomposites were investigated at 298 K. The rGO/SiO2 nanocomposite SG 0.30 showed a superior adsorption of NR dye. In regard to NR at pH 5, we measured a superior adsorption capacity of 66.635 mg/g at an initial NR concentration of 50 mg/L. The experimental adsorption capacity of SG 0.30 was 3.791 times higher than that of SiO2. Then, we compared the results with similar materials used for NR removal. Moreover, the water adsorption sites provided by the nitrogen- and oxygen-containing groups might be one of the reasons for the increased adsorption of water vapor. The broad range of properties of the rGO/SiO2 nanocomposite, including its simple synthesis, ability to be mass prepared, and strong adsorption properties, makes it a truly novel adsorbent that can be industrially produced, and shows potential application in the treatment of wastewater-containing dyes.


The purpose of this study is to explore to determine the maximum volume with doing permanent waving in flat crown of the head. The method was like this. First of all, the diameter, the ratio of the circumference of a circle to its diameter and the number of rotations were analyzed same hair using permanent waving rods each number of 110. Secondly, the increasing rate of volume of curls number of 110 was analyzed. According to the result of the experiment, as the number of permanent waving rods were bigger, the ratio of the circumference of a circle to its diameter constant was increasing but the number of rotations was decreased. When the permanent waving rods of each number 1-3(Big diameter) were used, the volume was decreased. That's because there was fewer rotation compared to the diameter and was no ample combed dried hair. Due to this kind of reason, there was no perfect curling. Once number 10 permanent waving rods (most small size) was used, the shape of curling was strong and the stability was made after combed dried hair. But volume was decreased by 9% because of the cohesive power. In case of number of 49 rods used, volume was increased. Volume was highest when permanent waving rods was number 5 which was used combing on base both morphology and numerical value.


INTRODUCTION :
Portal hypertension is the most common and dreaded complication
of chronic liver disease. It is responsible for the development of
gastroesophageal varices, variceal hemorrhage, ascites, renal dysfunction,
portosystemic encephalopathy, hypersplenism, and hepatopulmonary
syndrome. Bleeding from ruptured oesophagogastric varices is a major
complication of portal hypertension and a frequent cause of death. Only
40% of Child pugh class A patients have varices, while they are present
in 85% of Child pugh class C patients.
 AIM :
To evaluate the relationship of Doppler parameters of hepatic and
portal vasculature, hepatic vein wave forms with presence and size of
oesophageal varices in cirrhotic patients.
MATERIALS AND METHODS :
A cohort of cirrhotic patients identified by clinical, laboratory and
radiological parameters were evaluated. They were investigated for
oesophageal varices by oesophagoduodenoscopy and by Doppler
ultrasound. The relation between the presence and size of oesophageal
varices and Doppler parameters were studied.
RESULTS :
Fifty two patients were enrolled in this prospective study. There
were 44 male and 8 female patients. 23 patients were in Child Pugh Class
C , 16 in Child Pugh Class B and 13 in Child Pugh Class A.Small
oesophageal varices were associated with monophasic wave forms in
19.4%. biphasic wave forms in 38.7%, triphasic wave forms in 41.9%.
Large oesophageal varices were associated with monophasic wave forms
in 42.1%. biphasic wave forms in 52.6%, triphasic wave forms in 6.3%.
The p- value was statistically significant with 0.013 [p <0.05].Spleen size
greater than 15.3 was associated with large oesophageal varices which
was statistically significant. Except for splenic artery resistivity index,
none of the other Doppler parameters were statistically significant for
large oesophageal varices.
CONCLUSION :
Our study data suggested that monophasic hepatic vein wave
forms, splenic artery resistivity index, and spleen size greater than 15. 3
cms were related with presence of large oesophageal varices.These
parameters may help in targeted identification of patients with large
oesophageal varices and aid in their management.


We undertook this study to measure the reach of Oregon's legislated farm-to-school grant program among school districts and children, particularly low income, and examine changes in local purchasing, particularly fruit and vegetables, and the use of produce from school gardens in school meals. We conducted descriptive analyses to examine the reach and paired two-sample t-tests to examine average purchases of local products between school year 2014–2015 (baseline) and 2015–2016 (intervention). The study results indicate that the number of nonwhite students attending a district participating in farm-to-school nearly doubled in the intervention, and 89% of children eligible for free and reduced-price meals attended schools in participating districts compared with 39% of eligible children at baseline. Eighty-one percent of participating districts were low income, which is much higher than the percentage of districts characterized as low income statewide (65%). The policy also increased the average total local food purchases for low-income districts, particularly fruits and vegetables. The results suggest that the opt-in approach to the grant program facilitated greater a * Corresponding author: Kristen C. Giombi, RTI International; 3040 E. Cornwallis Road, P.O. Box 12194; Research Triangle Park, NC 27709 USA; +1-919-541-7330; email@example.com b Anupama Joshi, National Farm to School Network, San Francisco, CA 94129 USA. Joshi is now Executive Director, Blue Sky Funders Forum, New York, NY USA; firstname.lastname@example.com c Caroline Rains, RTI International; 3040 E. Cornwallis Road, P.O. Box 12194; Research Triangle Park, NC 27709 USA; +1-919-485-5607; email@example.com d Jean Wiecha, RTI International; 3040 E. Cornwallis Road, P.O. Box 12194; Research Triangle Park, NC 27709 USA; +1-781-434-1739; firstname.lastname@example.com Funding Disclosure The research reported in this article was funded by Healthy Eating Research (HER) and the Robert Wood Johnson Foundation (RWJF). Journal of Agriculture, Food Systems, and Community Development ISSN: 2152-0801 online https://www.foodsystemsjournal.org 140 Volume 9, Issue 3 / Spring 2020 participation from low-income districts that may otherwise have not accessed the grant program. Oregon's policy approach of designating funds for procurement and/or education grants (versus generic farm-to-school grants to be used at the discretion of the district) enabled the prioritization of these activities in grantee districts. Future research can help develop a more thorough understanding of the long-term impacts of Oregon's farm-toschool policy on children's health outcomes and on other intended outcomes on farmers and the local economy.


Adolescents with deafness exhibit higher mental health problems when compared with their hearing peers. There is limited information on the mental health problems of adolescents with deafness living in the sub-Saharan Africa. The aim of this study was to determine the prevalence of mental health problems in a group of deaf adolescents and the relationship with socio-demographic characteristics and to compare with their hearing counterparts. Materials and Methods: Teachers of 102 deaf adolescents and 102 age- and sex-matched hearing adolescents completed the Strengths and Difficulties Questionnaire (SDQ). Severity of deafness was assessed using Pure Tone Audiometry, using a five-frequency average. Results: The results showed that 88.2% and 11.8% of the deaf participants had profound and severe forms of deafness respectively. The prevalence of behavioural problems was significantly higher in the deaf adolescents than the control, as assessed by their teachers' (64.3% vs. 35.7%; p < 0.001). Ninety seven percent of the deaf participants reported no hearing aids use. Parental separation/divorce and mother's educational status were significantly associated with higher rates of behavioural problems (p < 0.05). There was no significant association between severity of impairment and mental health problems. Conclusion: Almost all the factors associated with deafness that are highlighted in this study are preventable through appropriate health and social interventions such as hearing aids, and will require that appropriate policy measures are put in place.


At the COMPASS experiment a sample of ∼380000 exclusive events of diffractive pion dissociation on a lead target into a π−π+π−π+π− final state has been recorded in 2004. The 5π invariant mass spectrum shows a momentum transfer dependent structure peaking around 1.8 GeV/c2. In the (4π)0 subsystem there is a clear signal for the f1(1285) resonance decaying into 4 pions. In this note we describe the data sample and explore the physics potential of this final state.


We sought to compare effects of remifentanil- and fentanyl-based anesthesia on the morphology of somatosensory evoked potentials (SSEPs) and speed of recovery from anesthesia. Forty-one patients undergoing spinal surgery and requiring intraoperative monitoring of SSEPs were randomized into two groups. In Group 1, anesthesia was induced with sodium thiopental and maintained with fentanyl, 50% nitrous oxide in oxygen, and 0.5%–0.75% isoflurane. In Group 2, anesthesia was induced with sodium thiopental and maintained with remifentanil, 50% oxygen in air, and 0.5%–0.75% isoflurane. The variables compared included hemodynamic changes during the induction and intubation, the interval from the end of anesthesia to extubation, intraoperative blood loss and fluid administration, and changes in latency and amplitude of the P37–N45 component of posterior tibial nerve somatosensory evoked potentials and the N20–P24 component of median nerve somatosensory evoked potentials. The two groups were matched for demographics, ASA physical status, and duration of surgery. Hemodynamic profiles after the induction and intubation were similar. There were significant differences between groups in time intervals from the end of anesthesia to extubation (15.3 ± 12.8 vs 5.3 ± 2.3 min;P = 0.0001) and ability to follow verbal commands (14.6 ± 11.9 vs 4.5 ± 2.4 min;P = 0.0001), with the Remifentanil group showing earlier recovery. Variability (coefficient of variation) of P37–N45 latency was greater (0.026 vs 0.014;P = 0.001) in the Fentanyl group.


Studied the peculiarities of oxidative stress of 32 women with external genital endometriosis (EGE) endometriosis without thyroid gland pathology and 30 women with external genital endometriosis and hypothyreosis age from 20 to 41. Estimation of indexes of oxidative stress, ultrasound investigation of thyroid gland and organs of small pelvis, laparoscopy. It was established, that when hypothyreosis and external genital endometriosis are combined, the changes in condition of oxidative stress take place more openly and it complicates the course of external genital endometriosis.


The increasing prevalence of hypothyroidism, which can cause endocrine dysfunction, abnormal neurological function, and cardiovascular and cerebrovascular injuries, poses serious health problems. Thyroid hormone supplementation constitutes the current main therapeutic method for hypothyroidism, yet it has many limitations and risks and is not suitable for everyone. Therefore, it is necessary to seek alternative and complementary treatment methods. It has been proven in practice that traditional Chinese medicine (TCM) possesses multi-channel comprehensive characteristics for the treatment of hypothyroidism and has more advantages than single thyroid hormone supplementation. Through a comprehensive examination of existing literature about TCM efficacy in addressing hypothyroidism, we have meticulously consolidated the most recent research findings on prescriptions and herbal substances employed in the treatment of this condition. Furthermore, we have explicated their respective functions in the management of hypothyroidism, thereby offering valuable perspectives and recommendations for the prospective utilization of natural remedies in its treatment.


Research emphasises the fundamental role of research data management (RDM) in enhancing academic and scientific research. This paper intended to examine RDM in Iraqi Universities, identify the current challenges of RDM and propose influential RDM practices. Data collection employed a self-administered questionnaires distributed to 155 postgraduate students and 20 faculty members from five universities in Iraq. Research findings revealed that there is a lack of proper RDM. Postgraduate students and researchers were managing their own research data. Main challenges of maintaining a good RDM involve lack of guidelines on effective RDM practices, insufficient of adequate human resources, technological obsolescence, insecure and inefficient infrastructure, lack of financial resources, absence of research data management policies and lack of support by institutional authorities and researchers negatively influenced on research data management. Postgraduate students and researchers recommend building research data repositories and collaboration with other universities and research organisations.


"We Serbs must militarily defeat our enemies and conquer the territories we need." Vojislav Maksimovic, Member Bosnian Serb Parliament "I don't see what's wrong with Greater Serbia. There's nothing wrong with a greater Germany, or with Great Britain." Bosnian Serb Leader Radovan Karadžić The break-up of Yugoslavia has come about as a result of national, economic and political conflicts which by the end of 1987 had taken on unprecedented dimensions. At that point, latent political conflicts between various republics came into the open. More specifically, the conflict between Serbs and Albanians in Kosovo had turned into a low-intensity war. Under Slobodan Miloševićs leadership in Serbia, the Serbo-Slovenian conflict over Kosovo deepened, forcing other republics and provinces to take sides. The Slovenian leadership opposed a military solution to the Serbo-Albanian conflict in Kosovo. By 1990 the Serbo-Slovenian conflict had spilled over into Croatia, completely polarizing the Yugoslav political elite into two distinct camps; one encompassed Slovenia and Croatia, the other Serbia and Montenegro, with Macedonia and Bosnia-Herzegovina playing the role of unsuccessful mediators.


Freeze‐coring and bulk sampling are routine methods used to sample subsurface spawning gravel under shallow water. Both methods have limitations. Freeze‐coring is not believed to representatively sample coarse grain sizes and the sample volumes are relatively small. Conversely, when bulk sampling, even within an enclosure, some fine sediment is suspended and washed away from the sample. This paper assesses the biases in sampling performance between the two methods and determines whether the loss of fines that occurs when bulk sampling could be predicted and thus corrected for.


Abstract : The following sections describe the research that has been accomplished during the entire grant period form September 1, 1991 to March 31, 1995, with partial support from the Air Force Office of Scientific Research and summarizes the papers, prototype systems and theses produced on the grant. Several major areas will be discussed. These are Cooperative Databases Systems, Combining Knowledge Base Systems, Disjunctive Deduction Databases, Extensions to the Semantics of Logic Programming and Parallel Logic Programming. During the first year of the grant we emphasized theoretical aspects of work in deductive databases and knowledge base systems. During the second year we stressed the development of tools and techniques to transfer the theory into practical systems. During the third year we developed prototype systems and experiments with them. Technological developments were made in Cooperative Database Systems and Disjunctive Deductive Databases. New theoretical developments were achieved in the Semantics of Logic Programming and in Combining Databases.


variables that may affect the way in which businesses contribute to political finance. In Chapter four, for example, he compares the 'subtle, complex, long term' nature of business financing in Australia to the Chinese notion of 'guanxi' (p. 93). Guanxi is (arguably) better understood as a cultural and societal connection. The comparison here in the context of a business financing of politics is fair, but hints at an area of study that might give us an even greater understanding of these exchanges. Secondly, although the book is about the nature of money there is no mention of the 'revolving door' between business and politics. This is understandable – an entirely separate book could be written on this particular corrupt exchange – however an acknowledgement of its incidence would not have been gone amiss. The most persuasive arguments are saved for the final chapters; his rejection of the two dominant positions, 'that business cash in politics is bribery' but also 'that it has no influence' is logically robust (p. 136). McMenamin concludes that money is 'multilingual': to better understand the relationship we must consider each country as being made up of potentially significant independent variables. That is not to say that McMenamin shirks the challenge of drawing generalisable conclusions; rather the book does not focus on 'proclaim(ing) what is and is not corrupt' but instead 'it shows how democracies might relate their political values to the types of behaviours prevalent in their political systems (italics my own)' (p. 136). The book is less about corruption and more about gaining a greater understanding of the (sometimes corrupt) relationship between business financing and political parties. A more nuanced view of this relationship might allow us to better differentiate between the notion of legitimate and illegitimate exchange. McMenamin's work stands as a vital contribution to the field, it also provides a springboard – and potential framework – for continuing study in the area.


Gender inequality is defined as the social phenomenon in which men and women are not treated equally. Unfortunately, when it comes to studies of sexual dysfunction in diabetes, the scale once again seems to be tilted in favour of the males. A PubMed search of '"Female sexual dysfunction" AND diabetes' yields less than 150 results while a similar search for the male gender leads to nearly 4000 publications. The scientific community clearly has not shown enough interest in this topic.


A compact planar Wilkinson power divider is proposed using two-section asymmetrical T-structures to achieve a significant size reduction and retain a mimic return-loss bandwidth as compared with the conventional one. The asymmetrical T-structure is realised by two series high-impedance lines with unequal electrical lengths and a shunt low-impedance line. The two-section configuration has the advantage of decreasing the shunt stub size, and then achieving an optimally miniaturised circuit layout. The developed power divider has a 66.5% 15 dB return loss bandwidth and only occupies a 12.7% circuit size of the conventional one. The measured results of the developed power divider are in a good agreement with simulated results.


Abstract A simple and efficient procedure for determining the propagation characteristics of arbitrarily shaped inhomogeneous waveguide is described. This procedure was mainly based on effective-index method1 and Ritz-Galerkin method. 2 Our procedure can be easily implemented on a small personal computer. We compared the results with those obtained by other method. 3 It was shown that the results obtained for mode spectra and field distributions are also accurate even in the case closed to the cutoff region.


To the Editor—In their letter [1], Kaye and Sobel express concern regarding the model described in our recent review [2] in which we suggest that recurrent urinary tract infections (UTIs) may in part be attributable to the ability of uropathogenic Escherichia coli (UPEC) to invade and persist within the bladder epithelium. This idea is based on results from numerous studies dating back to 1998 that used bladder cell cultures and mouse models of UTI [3]. In mice, persistent bacterial populations within the bladder are often intracellular, as assessed by gentamicin protection assays and microscopy, and unfazed by antibiotic treatments that effectively sterilize the urine. Ongoing studies in our lab and published work using mice indicate that these intracellular bacteria can reemerge sporadically and grow to high titers within the bladder lumen days to weeks after the cessation of antibiotic treatments (eg, [4–6]). The statement in our review that UPEC can persist intracellularly within the bladders of mice "without any overt clinical symptoms" was not the best choice of words and was perhaps too anthropomorphic [2]. We simply meant that mice could harbor intracellular UPEC reservoirs without displaying any obvious signs of inflammation and in the absence of any detectable bacteria within the urine.

Epidemiological studies support the possibility that intracellular bacterial reservoirs within the urinary tract are responsible for many recurrent UTIs in women, but these data may also be explained by the persistence of UPEC reservoirs within local environments outside of the urinary tract (discussed in [7]). Ex vivo assays show that UPEC can invade human urothelial cells in tissue explants from volunteers, and the analysis of shed human urothelial cells collected from the urine of women with UTI symptoms indicates the presence of intracellular E. coli [8, 9]. Together, these sorts of observations suggest that intracellular UPEC reservoirs are likely more than a mouse-specific laboratory phenomenon. However, Kaye and Sobel are correct in noting that the ability of UPEC to persist long-term intracellularly within the human urinary tract has not been established. Determining if intracellular UPEC reservoirs contribute to recurrent UTIs within the human population is a daunting task, plagued by issues of tissue procurement and contamination, possible reinoculation of the bladder by UPEC from niches outside of the urinary tract, and limited means to accurately detect small numbers of bacteria within a relatively enormous tissue. Ultimately, defining the relevance of intracellular UPEC reservoirs to the etiology of recurrent UTIs may only come to light with the development of approaches that can eradicate the reservoirs. We of course agree with Kaye and Sobel that it is premature to alter treatment protocols for recurrent or chronic UTIs outside of controlled clinical investigations based solely on results from mice, but we also feel that it is important to consider alternate rational explanations for recalcitrant UTIs, whether or not they gibe with the traditional view that UPEC act as strictly extracellular pathogens.


The present invention provides a card issuing system, a card issuing server, and a card issuing method and program, in particular a service providing server including an authentication ticket creating unit for encrypting access authentication information and creating an authentication ticket, and an authentication ticket transmitting unit for transmitting the authentication ticket to a card issuing server; where the card issuing server includes an authentication ticket verifying unit for decrypting the authentication ticket and verifying the authentication ticket, a verification result notifying unit for notifying the verification result of the authentication ticket to the service providing server, a connection information transmitting unit for transmitting connection information for connecting to the card issuing server to the service providing server along with the verification result of the authentication ticket, and an authentication information verifying unit for comparing and verifying the access authentication information of the authentication ticket and access authentication information stored in the IC chip of the information processing terminal.


Objective To investigate the effect of vitamin K on concentration of osteopontin in the urine of patients with urolithiasis.Methods Thirty cases of urolithiasis were treated with vitamin K3 injection (12 mg/day for 7days),and 30 healthy volunteers served as controls.The urine specimens were collected in patients before and after treatment and in controls.The concentrations of osteopontin in urine were determined by using Western blotting.Results The concentrations of osteopontin in urine were increased by 18.7% after vitamin K3 treatment (P < 0.05).The concentrations of osteopontin in urine in vitamin K group before vitamin K administration were 93.0% higher than in control group,but there was no significant difference (P =0.36).The concentrations of osteopontin in urine in vitamin K group after vitamin K administration were 129.0% higher than in control group (P < 0.05).Conclusion Vitamin K can clinically up-regulate the expression of osteopontin,and inhabit the formation of urolithiasis.

Key words:
Vitamin K;  Urolithiasis ;  Osteopontin


With 550 000 new cases diagnosed annually and $37 billion spent per year,1 heart failure (HF) with reduced ejection fraction is one of the largest contributors to disease burden and healthcare expenditure in the United States. Despite significant progress in the treatment of HF2,3 with medications, the prognosis of HF remains dismal, with a mortality rate of 42% at 5 years after diagnosis. Therefore, understanding the underlying molecular pathways in the transition from established cardiovascular disease to HF may spur the development of novel biomarkers and therapeutic targets.

The heart responds to stressors such as hypoxia (in myocardial infarction [MI]), increased wall stress (in valvular heart disease), and neurohormonal/metabolic stress (in diabetes mellitus and hypertension) by cardiomyocyte hypertrophy and fibrosis. Although initially compensatory for increased wall stress or myocyte loss, the molecular pathways that underlie pathological hypertrophy are ultimately maladaptive, recapitulating further hypertrophy, contractile dysfunction, apoptosis, and fibrosis. The progression to HF is associated with a characteristic cascade of altered intracellular signaling and gene expression, representing a final common pathway to ultimate decompensation. The various signaling pathways that underlie pathological hypertrophy and the progression to HF have been the subject of intense investigation and are summarized in multiple review publications.4–9. More recently, considerable attention has been paid to microRNAs (miRNAs), a novel biological control mechanism with the ability to regulate entire molecular networks by complex feedback and feed-forward mechanisms. Several reviews have summarized recent findings implicating miRNAs in cardiac development and disease.10,11 In the past few years, the discovery of circulating miRNAs has led to their investigation as biomarkers and mediators of cell–cell communication. This review focuses on recent developments detailing the role of miRNAs in the pathogenesis of HF, their potential role as biomarkers, and their use as …


Transposition of the great arteries (TGA) is a relatively common, yet complex congenital heart disease caused by an inversion of the origins of the two main vessels exiting the heart. This life-threatening condition includes several subtypes of cardiac malformations that range from relatively simple cases where this defect is isolated, to more complex ones associated with other cardiac anomalies. Surgery is the treatment of choice for these pathologies, but the high variability of anatomy demands a rigorous evaluation in order to choose the most appropriate surgical strategy for each individual patient. Along the years, various surgical procedures have been invented, allowing the repair of cases of increasing complexity. This thesis is a presentation of our personal experience in the management of TGA, where a new technique proposed by Yamagishi et al. in 2003 is exposed, with some modifications, in the context of the currently used techniques. We will also propose a new approach in the choice of strategy.


We report studies of photoexcited carrier dynamics in GaAlAs/GaAs superlattices as a function of excitation power using optical technique. At low power, we observe a quadratic behavior of luminescence intensity, due to competition between electron-hole radiative recombination and trapping by defects, At higher power, a departure from this behavior is interpreted by a fast spatial expansion of the plasma. However, over the whole range, the measured decay time is mainly related to the trapping process. Although it is a rather old topic, carrier transport in semiconductors is still a matter of controversy. For instance, a few years ago there was much of a debate about the possibility of a fast plasma expansion at relatively high density as suggested by M. Combescot /I/. The appearance of the new microstructures (quantum wells, su$erlattices) has given a boost to the study of semiconductors. Indeed, physicists have now new degrees of freedom in the design of samples. For instance, superlattices (SL) are strongly anisotropic materials. In SL, much of the research has been devoted to the study of transport parallel to the interfaces, but more recently a growing interest has appeared for the transport perpendicular to the interfaces (vertical transport) / 2 / . Here, we present a study of the effects of the carrier density on the properties of a GaAs/GaAIAs SL. The A1 composition in the alloy is 30% and the GaAs and GaAlAs successive layers are both 30 A thick. The sample held at 77 K in a cryostat is photoexcited by a frequency-doubled mode-locked Nd-YAG laser. The laser can be used in two different configurations: without or with Q-switching; in the following these two configurations are respectively noted ML and QS. In the first one, a continuous train of pulses separated by 10 ns is produced (pulsewidth 100 ps). In the second one, bursts of such pulses are created: the width of the burst is about 1 us and the repetition rate is 8 kHz; this gives larger peak power than in the ML configuration and therefore increases the available dynamic range. The laser beam is focussed on the sample to 100 pm. The luminescence emitted is collected and dispersed by a double moaochromator. Luminescence spectra are obtained with conventional photon counting techniques. Single-photon counting, using a constant fraction discriminator and a time to amplitude converter, gives access to the time evolution of the intensity at a given wavelength. The SL we have studied has a sufficiently short period to insure a large overlap between the wavefunctions of neighbouring wells and an increased 3D behavior of the carriers. Therefore, the exciton has a sufficiently low binding energy to be ionized at 77 K. This is evidenced by the two luminescence spectra shown figure 1. They have been obtained in two different experimental conditions: ML (average power incident on the sample: P=3 mW) and QS ( P=ll mW); therefore the QS spectrum corresponds to a much higher peak power. Both spectra have a characteristic Boltzmann high energy tail as it can be expected for the recombination of free carriers. The effective temperatures are 90 K (ML) or 140 K (QS). Article published online by EDP Sciences and available at http://dx.doi.org/10.1051/jphyscol:19877128 C7-538 JOURNAL DE PHYSIQUE 1.65 1.70 eV 1.65 1.70 eV Figure 1: Luminescence Spectra. Average Power: 3 mW (ML -6 dB), 11 mW (QS 0 d ~ ) Figure 2,3: Luminescence intensity versus excitation power Figure 2: ML configuration


This essay explores the enduring relevance and challenges of Caribbean Négritude poetry, with specific emphasis on the work and thought of Aimé Césaire and Léon-Gontran Damas. The decolonizing imperative that speaks through their work retains an agonic immediacy and political validity, exemplified by the radical hip-hop voices that emerged following the 2005 youth uprisings in French banlieues. The essay pays particular attention to the opening salvo of the Négritude movement, Damas's relatively underanalyzed Pigments (1947) and Césaire's more celebrated Notebook of a Return to the Native Land (1939–56), the former as prefiguration of Frantz Fanon's psychoanalytical exploration of "the fact of blackness" and the latter as a transcendence of narrow identitarian affirmation announcing a liberated space: the "convocation of conquest" in which there is "room for all."


The post-Covid shutdown U.S. labor market is characterized by many open jobs and substantial unemployment. Despite numerous hypotheses regarding this paradoxical situation, existing models in labor economics lack the features necessary to adequately evaluate the potential policy remedies or causes. I construct a search model to reproduce the prevailing dynamics, which I then use to evaluate the employment impact and effect on the welfare of low-income workers from large-scale transfers, unemployment benefits, and an earnings subsidy. One-off transfers hardly affect employment in a downturn. Raising unemployment benefits by $300 per month leads to a 0.6 point increase in the unemployment rate. Adding an earnings subsidy to unemployment benefits raises employment by 7 percentage points at a 23% lower level of inequality, yet increases costs by only 16-30%. In contrast to a compensating differentials framework, the model shows that lower earners tend to be more at risk for layoffs, and that this effect is stronger following a negative aggregate shock. Following a simulated shock, mean consumption falls by 5% yet consumption at the 10th percentile drops by 16%. Although the risk borne by lower earners is often greater, their savings are often lower, because they have less consumption to seek to smooth and less opportunity to accumulate savings.


Among the derivatives of the N alpha-arylsulfonylated omega-amidinophenyl-alpha-aminoalkyl carboxylic acids, the primary amides of N alpha-arylsulfonylated 2-amino-4-(4-amidinophenyl) butyric acid proved to be compounds with strong antiplasmin and antitrypsin activity, they exert, however, only slight inhibitory effect on thrombin. So far, no benzamidine derivatives with strong inhibitory effects on plasmin but with weak antithrombin activity have been known. The secondary amides of the N alpha-arylsulfonylated 2-amino-4-(4-amidinophenyl)butyric acid possess slight inhibitory effects, the corresponding derivatives of 2-amino-5-amidinophenyl valeric acids, however, are potent inhibitors of thrombin.


Many universities have developed a series of management systems and measures to standardize the teaching management,and achieved great results.But in teaching mode and system management,and evaluation of incentive mechanisms there are still some problems affecting the college teaching,management which effect the functioning of the mechanism.It is necessary to have a rational conclusion to improve the quality of teaching management.


Purpose
This investigation aims to analyze the steel-flux interface level fluctuation because of electromagnetic stirring and its process parameters in a continuous casting billet mold.

Design/methodology/approach
An un-coupled numerical model for electromagnetic field generation and a coupled numerical model of electromagnetic field and two-phase fluid flow have been developed. The two-phase fluid flow has been modeled using volume of fluid method, in which externally generated time-varying electromagnetic field is coupled and analyzed using magnetohydrodynamic method. Top surface standing wave stability criteria are used to study the criticality of interface stability.

Findings
Results show that application electromagnetic field for stirring increases the interface level fluctuation, specifically at the mold corners and near the submerged entry nozzle. The increase in current intensity and stirrer width barely affect the interface level. However, interface level fluctuation increases considerably with increase in frequency. Using stability criteria, it is found that at 20 Hz frequency, the ratio of height to wavelength of interface wave increases much above the critical value. The iso-surface of the interface level shows that at 20 Hz frequency, mold flux gets entrapped into the liquid steel.

Practical implications
The model may be used during optimization of in-mold electromagnetic stirrer to avoid mold flux entrapment and control the cast quality.

Originality/value
The study of mold level fluctuation in the presence of in-mold electromagnetic stirrer has rarely been reported. The criticality of stirrer process parameters on level fluctuation has not been yet reported. This study lacks in experimental validation; however, the findings will be much useful for the steelmakers to reduce the casting defects.


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The scientific article analyzes the peculiarities of the legal regulation of the joint investment insti-tutions of the European Union. The concepts and types of joint investment institutions have been defined, the legal regime and the peculiarities of their activity have been analyzed. The state in which the right conditions for investment funds are created has in their person an ef-fective mechanism for the development of the securities market, which play a significant role in the cross-sectoral redistribution of capital, enhance the stability of the stock market, stimulate both the internal investment process and foreign investment, promote empowering the state with regard to domestic bor-rowing. The positive role of co-investment institutions in the macroeconomic context is confirmed by the preferential nature of investment funds taxation (or lack thereof), which is characteristic of the national legislation of the vast majority of countries.


After the anti-Japanese War broke out,the enlightened gentlemen in the shaanxi-gansu-ningxia border region surmounted their class status,identified with and held out the Chinese Communist cause.They responded actively to the government building of border region.They were famous for democratic politics.The enlightened gentlemen participated in government and politic affairs in different ways,such as congress government,the gentlemen visit of society and they were engaged in having an informal discussion about the situation at home and abroad.They made lots of influential motion in military,politics and law,finance,culture and education,economy and so on.It promoted the development of government Cause.They made indelible contribution in anti-Japanese War and the victory of liberation war.


After axillary node dissection for reasons other than breast cancer, such as malignant melanoma of the skin, lymphatic drainage of the breast tissue is diverted to the internal mammary or supraclavicular lymph nodes. The authors describe a patient who had an axillary node dissection for malignant melanoma of the back in whom breast cancer developed 22 years later. Sentinel node lymphoscintigraphy performed the night before surgery showed diversion of lymphatic drainage to the internal mammary lymph nodes in only the delayed images acquired at 18 hours.


An antigen-specific CD4+ T cell clone, OK2.21, and a hybridoma clone, A3.4C6, induced cytolysis and DNA fragmentation of appropriate targets in the presence of an anti-CD3 monoclonal antibody (Mab). In a double chamber system, OK2.21 killed TNF-sensitive targets that were separated from the T cells by a porous membrane. The killing was completely inhibited by anti-TNF antibody. On the other hand, neither OK2.21 nor A3.4C6 killed a TNF-insensitive target, A20.2J, that was separated from the T cells. Furthermore, the cytotoxicity and DNA fragmentation of A20.2J by anti-CD3 Mab-activated T cells were inhibited by both anti-LFA-1 and anti-ICAM-1 Mab. These results suggest that TNF is the only soluble cytolytic factor involved in CD4+ T cell-mediated cytotoxicity, and that TNF-independent apoptosis occurs through cell-to-cell contact via a LFA-1/ICAM-1 system.


A systematic scoping review of health system Performance and Quality Indicators (PQI) related literature for evaluating publicly funded home care programming was conducted. Through the scoping review we identify PQIs, map these based on quadrants of the Institute for Healthcare Improvement's (IHI) Quadruple Aim, classify these PQIs under general "areas of focus" categories, and present recommendations for use. We selected all articles that identified, referenced, proposed, and/or described at least 1 PQI to measure home care service programming. Minimum inclusion criteria were a description of 1 or more PQIs designed to evaluate and/or measure home care programming, outcomes of home care clients and/or caregivers, or overall system impacts of home care service provision. The review identified 3,475 citations. A review of the abstracts led to the retrieval of 510 full-text articles for assessment of which 105 articles were selected for detailed review and extraction of identified PQIs. Of the 105 identified articles a total of 829 unique PQIs were gathered. Based on the IHI Quadruple Aim, 661 unique measures were identified as Clinical Outcome, 35 as Healthcare Provider Satisfaction, 99 Patient Experience, and 34 in the Financial/Sustainability quadrants. Many patient outcome specific PQIs exist, followed by patient experience measures. Very few PQIs exist in the financial or healthcare provider experience quadrants. The lack of indicators across all the IHI Quadruple Aim quadrants is an opportunity for further development supporting home care quality oversight.


In-store cooked food retailing is seemingly a new concept in Botswana, with almost all the supermarkets engaged with the concept. However, to the best of our knowledge, little or no research has been carried out on this matter. Healthy and clean eating has become a major concern for consumers due to the HIV/AIDS pandemic. However, the in store foods are prepared without the consumers' presence and the customers end up using in store cues to help them in selecting the best store to buy their food from. Akbay et al (2005) and Hiemstra and Kim (1995) found out that food quality and variety and environment significantly affect customer satisfaction in fast food outlets. Food quality, cleanliness and value are the three most important attributes in fast food restaurants.


Various control circuitries in an aircraft are housed on printed circuit boards. These control circuitries usually consist of microcontrollers or programmable logical devices to carry out execution of instructions based on various control parameters. The control circuitries are responsible for the smooth functioning of an aircraft and are responsible for various controlling actions such as fuel control, auxiliary power unit control, flight controls and navigation systems control. The programmable logic devices need to be supplied by a reliable power supply. As a failure in their operation could lead to catastrophic consequences. The power electronic circuitries involved in these power supplies contain semiconductor switching devices and they are vulnerable to failures. Hence an inherit fault tolerant capabilities of a DC-DC step-down converter is explored in this paper. This fault-tolerant converter provides more reliable operation than regular power converters for aircraft control and embedded system applications. In this paper, the authors have conducted literature survey, carried out a study and simulation of the aircraft electrical distribution system and then integrated the fault-tolerant converter.


Synopsis The relative speed of recall of pleasant and unpleasant experiences was investigated in patients with unilateral temporal lobe epilepsy and after unilateral temporal lobectomy. Indications have been obtained that right, but not left, temporal lobe dysfunction may impair hedonic aspects of memory selectivity.


The effect of 5-fluorouracil on the activity of pancreatic enzymes was studied in rats with acute pancreatitis. 5-Fluorouracil was injected intraperitoneally in a dose of 4.5 mg per 100 g body weight. Pancreatic transaminidase as well as serum alpha-amylase and trypsin levels decreased starting from 3--6h after the induction of acute pancreatitis. 5-Fluorouracil inhibited RNA and DNA synthesis and blocked the synthesis of pancreatic enzymes.


Although the political settlement of 1919 was based on the principle of nationalism, the expectation was that the economic system would remain international. But in the post-war decade nationalism spread steadily to economic matters. In 1920 the United States underwent an extreme reaction toward political and economic national isolation which it was forced to temper somewhat in the ensuing ten years. The New Deal shows a tendency toward international politicl co-operation, but only toward such as is consistent wich a plan of national economic development. Internally, the New Deal promises to strengthen American national solidarity by increasing the integration of economic activity and organization around a national plan and by emphasizing the difference between that wich is comprised in the national plan and that wich is outside it.


Dirac point supports two degenerate intrinsic PC modes. Vortex like PC mode at Dirac point can be excited and coupled in a hollow core PCF when it is helically twisted about the propagation axis.


A historical city constitutes a whole by sheltering buildings those belong to past period. In Anatolia, there are developed historical cities that its historical core had been formed in ancient times. However, these cities have been reformed by Turkish nation's immigration spreading in a long duration to Anatolia. Especially, the cities in Muslim-Turkish nations like Seljuk and Ottoman Empire period has been traced morphology such as urban-systems, settlement-tendency, castle-construction, and development of city centered-bazaars those reflect its era. In this study, city system, residence-tendency, castle-construction and the development of city-bazaar of Seljuk and Ottoman Empire period have been investigated.


The present article aims to explain Constitutional Amendment Proposal 64/2016, given that the current system is negligent along with the victims related to the crime of rape, triggering a mismatch between law and society. In addition, the study seeks a better understanding and reflection, seeking a concise assimilation of its content, composed of the possibility of the crime of rape becoming imprescriptible and non-enforceable by changing the current wording of paragraph XLII of article 5 of the Constitution. The method applied was the legal deductive, based on the interpretation of the Constitution, legislation, theories, jurisprudence and doctrines, with a hermeneutic-dialectic approach. It is concluded that the proposed amendment to the de facto constitution will provide greater security to the victims of crime, so that the amendments presented are consistent with social developments and certainly provide a response to legislative and social weaknesses.


Accurate solar power forecasting has a decisive effect on the formulation of day-ahead power system dispatch strategies. At present, there is every confidence that paring numerical weather prediction with a physical model chain is the state-of-the-art solar forecasting method suitable for grid integration. Leveraging this two-stage solar power forecasting framework, the total cost benefits of day-ahead power system dispatch have been quantified based on a modified IEEE 24-bus system. The numerical experiment results reveal that the two-stage forecasting method saves 2.1 million dollars (1.33%) per year, as compared to the benchmark.


Objective:To evaluate three-phase spiral CT contract-enhanced(CE)scan in the diagnosis of carcinoma of pancreatic body and tail and its clinical application.Methods:Thirty-two cases with carcinomas of pancreatic body and tail underwent plain CT and three-phase CE scan.The CT value of normal pancreas and tumors were measured and compared.According to CT findings,the diagnosis and resectablities were assessed.Results:Among 32 cases,22 showed slight enhancement,9 showed middle enhancement,1 showed non-enhancing cystic lesion.Turmor-pancrea contrast values in arterical phase were 23.45±12.62,64.53±27.34 in pancrdatic parenchymal phase and 41.28±19.12 in portalvein phase.The datas of three groups have difference in statistics(P0.01).Conclusions:Multislice spiral CT three-phase CE scan is valuable in detecting the carcinoma of pancreatic body and tail.


In this paper we prove a topological lemma on real valued random variables which implies the basic ingredients for the proof of the Fundamental Theorem of Asset Pricing in the two period case. In particular, previous results of Stricker and of Schachermayer are special cases of our result. Our proof is considerably shorter and more transparent than previous proofs of related special cases.


167 Background: Several studies have shown that palliative medicine consultation can improve multiple patient-centered outcomes, especially when provided early. Our goal is to show that our electronic health record (EHR) trigger tool is a cost-effective way for hospitals to identify patients who may benefit from early consultation, improving outcomes such as hospital length of stay and facilitating appropriate disposition for patients with metastatic cancer.

METHODS
Retrospective chart review of 721 patients at an urban community hospital who were identified by a trigger system integrated into the Emergency Department (ED) EHR. Patients who met criteria for a palliative consultation as determined by ED physicians at the time of inpatient admission were tracked by the palliative medicine department as part of a pilot phase. Those that were triggered and received usual care made up the control group. The intervention group was made up of patients who were triggered and seen in consultation.

RESULTS
Patients who were seen within 3 days of trigger were found to have a mean length of stay of 7.57 days, while those seen after 3 days had a mean length of stay 10.61 days. Patients who were triggered for metastatic cancer were found to have differences in final disposition between the two groups. Discharge to subacute rehabilitation facilities (SAR) in these patients decreased from 24% in the control group to 12% in the intervention group, while use of home hospice more than doubled to 11%. The percentage of these patients dying in the hospital decreased from 18% to 12%.

CONCLUSIONS
Our study showed that earlier consultation was associated with shorter hospital length of stays if patients were seen within 3 days of being flagged as having palliative care needs in the ED. We also found that our EHR trigger doubled home hospice utilization in patients with metastatic cancer, decreased the proportion of discharges to SAR, and decreased in-hospital death in these patients.


We establish a generalization to an inequality that can be used to measure how badly the intersection of an open ball of the euclidean space with the conformal boundary, i.e. the metric boundary of a conformal deformation of the unit ball Bn , fails to be open in the euclidean sense. As an application to this, we show among other things that every point of a conformal boundary can be approached along a euclidean geodesical arc in a bounded set with respect to the intrinsic metric of conformal boundary. Mathematics subject classification (2000): 30C65.


Introduction- HER2 is now well recognized as a key factor in the development of certain solid human tumors .The expression of Her2/ Neu in
gastrointestinal malignancies is new concept with paucity of literature.
Aim- The present study was conducted in a tertiary care cancer hospital in India to evaluate Clinicopathological features in resected cases of
gastrointestinal cancer cases and their correlation with Her2/Neu expression by Immunohistochemistry.
Material & Methods- The present study was carried out in department of pathology at regional cancer tertiary centre from October 2017 to
October 2019. The cases were selected on basis of inclusion & exclusion criteria.Her2/Neu expression was assessed in all 100 cases.
Results- In present study HER2/neu status was determined on 100 cases by immune histochemistry and all IHC 3+ are accepted as HER2/neu
positive cases, 2+ were equivocal and 1+/0 were negative. Out of 100 cases, 8 cases (8%) show HER2/neu 3+, 5 cases were HER2/neu 2+, 20 cases
showed HER2/neu 1+ score and 67 cases showed Her2 Neu score 0. The mean age of all tumors was 53.7year (Standard Deviation 14.08 ) (P
=0.59). Mean age of gastric and GEJ cancer 57.1 year (SD-12.01), small intestine cancer 57.7 year (SD-7.41), pancreatobiliary cancer 55.50 year
(SD-14.86),colon cancer 54.5 year (SD-13.94),rectal cancer 52.1 year (SD- 15.45).Out of 100 cases , 59 cases were male and 41 were female
(M:F= 1.4:1In the GIT tumors no statistically signicant association was found between her2/ neu status with histological type , T stage , size of
tumor , grade and TNM stage . The only signicant association of Her/ 2 Neu was found with Modied Astler coller staging.
Conclusion- Modied Astler Coller stage can be used as screening test for centers where facility of Her2neu test not available.


Various studies suggest that the size of local unions affects the nature of internal political processes at both the local and the national union level. Data collected from delegates to the 1959 Constitutional Convention of the UAW indicate that large locals contribute more to democratic processes in the national union. The data also suggest that small locals may be less democratic internally than large locals but raise some questions regarding the applicability of customary indexes of democracy to small local unions.


We describe the Uppsala system for the 2017 DiscoMT shared task on cross-lingual pronoun prediction. The system is based on a lower layer of BiLSTMs reading the source and target sentences respectively. Classification is based on the BiLSTM representation of the source and target positions for the pronouns. In addition we enrich our system with dependency representations from an external parser and character representations of the source sentence. We show that these additions perform well for German and Spanish as source languages. Our system is competitive and is in first or second place for all language pairs.


Narran valley is famous for its beauty however anthropogenic activities are not only destroying the beauty of this valley but also lead to the pollution. Cr (VI) is considered as a major environment pollutant as it is mutagenic, carcinogenic and teratogenic. Current study deals with an attempt to know the Cr (VI) reduction potential of the indigenous bacterial isolates of soil of Narran valley. Total ten bacterial strains (JM1, JM5, JM6, JM7, JM8, JM9, JM10, J11, JM12, and JM13) were isolated from Narran valley soil. The morphological and biochemical characterization of selected strains were done. Maximum tolerable concentration of K2Cr2O4 was found to be 300 mgL for all of these strains. These bacteria were found to have multiple metal resistance. These strains could efficiently convert hexavalent chromium into trivalent form (96-98%) at an initial concentration of 300 μg mL of Cr (VI). In comparison with other purified isolates, (JM8) exhibited highest Cr (VI) reduction potential at all the preliminary concentrations (100, 300 and 900 μg mL). Best carbon and nitrogen sources for Cr (VI) reduction were sodium acetate and yeast extract, respectively. 16S rRNA gene sequencing revealed that JM9 and JM13 showed 99% similarity with genus Bacillus whereas JM8 was found to be homologous to genus Acinetobacter. FTIR study showed the contribution of sulphonate, carboxyl, amino and S-H groups of bacterial cell surface in the metal binding process. These chromium resistant bacterial isolates can be appropriate candidate for the remediation of chromate contaminated areas.


ABSTRACT
The purpose of this research is to know the effect of nursery rhyme to the investing of character education for children in Group A at TK Aisyiyah in Pucangan 1 Kartasura. This research was experimental research. The research Experimental design used was pre-experimental design that used one group pretest-posttest design. The subject in this research was 16 children from Group A. The data collection techniques in this research was conducted through interview, test, documentation, observation, namely nonparticipant observation. The data were analyzed through t-test. The result was the investing of character education for children Group A was 13,75 average value for pretest and 19,5 average value for posttest. The result of T-test analysis used program SPSS 16.0 for Windows was that paired sample t-test obtained t -15.057 <- ttable is -1.753 the result is that H0 is rejected and Ha is received. The conclusion of the research is that there is of the using of nursery rhyme influences the character education for children in Group A at TK Aisyiyah in Pucangan 1 Kartasura.
Keywords: Character Education, Nursery Rhyme.


A 400-MHz phase-mux-based O-QPSK transmitter (TX) for medical imaging applications is presented in this paper. The modulation signal is generated by selecting one of the four quadrature phases to the TX output via a proposed Phase MUX. An inverter-type power amplifier is utilized for it is compatible with the quasi constant-envelope nature of the O-QPSK modulation. Fabricated in a 0.18-mum CMOS process, the whole TX draws 2.9 mA from a 1.2-V supply. With a maximum 15-Mbps data rate, the TX achieves an energy efficiency of 0.23 nJ/bit and delivers an output power up to -7 dBm.


We have used tibiotalocalcaneal arthrodesis by retrograde intramedullary nailing in patients with rheumatoid arthritis with severe hindfoot deformity. A lot of bone often has to be removed to allow full correction, some of it on the tibial and some of it on the talar side of the ankle. Partial removal of the talar bone is not always sufficient to achieve correction in longstanding cases, and to avoid undue tension of the soft tissues, today in some cases we prefer to perform total talectomy and fuse calcaneus directly to the distal tibia, accepting some shortening. The technique is perhaps more commonly used for salvage of loosened or infected ankle prostheses, but it can also be used to transform a painful dislocated hindfoot to one that is pain-free in a normalized functional position.


A (A) a silane-containing ethylene interpolymer comprises ethylene interpolymer, and an alkoxysilane of at least 0.1 percent by weight (2) having a density of less than In one embodiment, such an ethylene interpolymer, based on the weight of the ethylene interpolymer both have a residual boron content and residual aluminum content of less than 100ppm less than 10 ppm. In addition, A. At least one electronic device, Bs. Multilayer electronic device module comprising the above ethylene interpolymer film in close contact with at least one surface of the electronic device is disclosed. Multilayer electronic device module according to the present invention, the potential induced degradation incurred ( "PID") has been shown to be reduced. .FIELD 1


The Public Service Broadcasting has historically been associated with two interrelated dimensions: a political and democratic dimension, and an educational dimension. It has an important role for forming an enlightened public opinion as an essential part of the political process. While contributing to the strengthening of democracy (apart from State and Market), the Public Service Broadcasting is also playing an educational role. In addition to information and entertainment, its duty is to protect and uphold high standards of quality in its programming that correspond to the moral model of societies. A third equally important dimension is the social integration dimension of Public Service Broadcasting and the relationship between society and publicity, and their interaction with Media. This paper seeks to ponder on the convergent dimension of Public Service Broadcasting highlighting its everyday sociability, both in terms of the topics, and in terms of its structure. What is important in this everydayness is that the general interest now seems framed by a motivation to see represented in the Public Service Media the daily lives of the very people to whom it is addressed. It is a discourse not only facing the objectivity and information, as well as to the subjectivity and authenticity


The effects of Total Ionizing Dose (TID) radiation on the cells and terminations of Superjunction MOSFET (SJ-MOS) and conventional power MOSFET (C-MOS) were studied by simulations, respectively. The same degradation trends in electrical parameters were found for the cells of these two devices; however, the breakdown voltage (BV) of the termination region in SJ-MOS shows much less sensitivity to TID radiation. The reason why SJ-MOS has a superior TID endurance is discussed in detail.


Clinical cardiac electrophysiology has evolved rapidly over the past several decades, allowing wide-ranging therapeutics to improve the lives of millions of patients.1 The progression from physiology-based investigations to large, randomized trials of new drugs and devices has allowed clinicians to treat patients with greater confidence and an increasing sense that interventions are evidence-based.2,3 Approaches to national health care reform have applauded this trend and the increasing authority and rigor of national treatment guidelines, with many leaders calling for greater adherence to evidence and guidelines alike.4–9

However, the nuances of the published literature may be lost in translation to patient care or obscured by formal recommendations, which become rapidly ingrained in current practice and the training of new clinicians.3 Trainees, in particular, may never question the genesis of these recommendations, and thus fail to appreciate the underpinnings of some of the most closely held views in clinical medicine. This article examines the hazards of this phenomenon in clinical arrhythmia management. We ask 3 questions, considered by many to be already settled by the existing evidence and forceful recommendations. We propose that considering these questions more closely illustrates areas in need of further debate and investigation and the importance of preserving critical thinking and clinical judgment.

### 1. Are Class IC Antiarrhythmics Contraindicated for Patients With Structural Heart Disease or Coronary Artery Disease?

This restriction is well known to cardiologists, internists, and medical students. The American College of Cardiology/American Heart Association/ European Society of Cardiology (ACC/AHA/ESC) 2006 guidelines for managing atrial fibrillation warn against using any class IC agent in patients with "ischemic heart disease or left ventricular dysfunction due to the high risk of proarrhythmic effects."10 Use of these therapies in patients "who have well-defined risk factors for proarrhythmia with that agent" has a class III, Level of Evidence A recommendation—"evidence and/or general agreement that a procedure/therapy is not …


The research on visual analytics for software maintenance has noticeabily advanced in the past few years. For many software projects, software maintenance needs an effective and efficient path from data to decision. Visual analytics (VA) creates such a path that enables the user to extract insights by interacting with the relevant information. This paper focuses on VA in software maintenance and has the following goals: investigate the VA adoption and suggest important implications for practice, and identify current research trends, open problems, and areas for improvement. To achieve these goals we conducted a systematic literature review with three research questions and assessed 51 studies published in the past two decades. The results indicate that there is a lack of collaboration between academic researchers and industry practitioners. This impedes the credibility of the proposed tools and methods due to lack of confidence in industry adoption. Furthermore, in this study we identified the need to expand VA support to other programming languages and software maintenance tasks.


Biocompatible and biodegradable block copolymers (BBCPs) have become increasingly important in polymer science, and have many potential applications in polymer materials. The structures of BBCPs, which are determined by the competition between crystallization, microphase separation, kinetics and processing, have a tremendous influence on the final properties and applications. In this review, the most recent advances are highlighted in the crystalline structures and morphologies of BBCPs with at least one crystalline block. Particular emphasis is placed on the influences of chemical composition, molecular architecture, crystallization pathway, and film thickness on the structures and morphologies of the block copolymers. The formation and the characteristics of the structures grown in the block copolymers are helpful for understanding the interplay between crystallization and phase segregation, morphologies, structural evolution and their applications.


Objective: To study clinical technique of avoiding false positive of tetanus antitoxin for skin test. Method: To choose right dilution; to strictly master the formulation of skin test and the technique of intracutaneous injection; to fix the best check time; to set the standard of assessing the result of skin test; to strictly master the injection techniqu, e of tetanus antitoxin. Result: To use the new methods for doing TAT skin test ,the positive rate is only 7.2% and after desensitization injection for the 7.2% patients .We get injection rate of 99.88%. Conclusion: We master strictly the formulation of TAT skin test, assess in the best time, inject TAT correctly. So, we can reduce the rate of false positive and increase the chance of patients for administrating.


In this note, I will prove a conjecture in [1], which is related to the invariants of a maximal parabolic subgroup of GLn+1. Consequently, the natural tensor invariants of this typical maximal parabolic subgroup of GLn+1 are determined when n ≥ r. 0. Introduction The purpose of this note is to prove Conjecture (0.1) proposed in [1], which is actually much related to tensor invariants of an distinguished maximal parabolic subgroup of GLn+1. The authors in [1] defined an enhanced reductive algebraic group G, which is naturally a semi-reductive group. In order to illustrate the tensor invariants of GLn = GLn ⋉ C n in EndC(V ) with V = C, they introduced a finite-dimensional degenerate double Hecke algebra D(n, r), and got a Levi Schur-Weyl duality for V = C in [1] (see [1, Theorem 4.3]) which is an analog of classical Schur-Weyl duality. By [1, Example 5.2], CΨ(Sr) ( EndGLn⋊Gm(V ) when n < r. However in the case n ≥ r, there is a conjecture EndGLn⋊Gm(V ) = CΨ(Sr) (0.1) (see [1, Conjecture 5.4]). In §2 of this article, I will give a proof of (0.1). Then it is a position to investigate the enhanced tensor invariants, and this is listed in §3. Note that GLn ⋊ Gm is a canonical maximal parabolic subgroup of GLn+1. It is worth mentioning that the study of invariants beyond reductive groups is a challenge (see [3]-[5]). Consequently the invariant property of G⋊Gm has its own interest. 1. Levi Schur-Weyl duality. 1.1. A general setting-up. In this note, all vector spaces are over a complex number field of C. Let G be a connected reductive algebraic group over C, and (V, ρ) be a finitedimensional rational representation of G with representation space V over C. We can define an enhanced reductive algebraic group G = G×ρ V as follows (see [1] explicitly): Regard G as a set, we have G = G× V ; For any (g1, v1), (g2, v2) ∈ G× V , (g1, v1) · (g2, v2) := (g1g2, ρ(g1)(v2) + v1). (1.1)