Background: Polypharmacy is a considerable problem in people with rheumatic diseases, including rheumatoid arthritis (RA), related amongst others to worse disease outcomes and increased cost for the health-system (1). Objectives: To assess polypharmacy in RA and usage of the health-care system (outpatient clinics) in a real-world setting. Methods: Medical records of 170 consecutive RA patients from a large outpatient service of a central hospital were retrospectively reviewed. Demographic characteristics, treatment for RA and comorbidities as well as frequency and type of visits to any outpatient services were recorded. The latter included rheumatologists, "medical specialties" doctors (general physicians, cardiologists, respiratory physicians, oncologists, dermatologists, gastroenterologists, hematologists, nephrologists and neurologists) and "surgical specialties" (general surgery, orthopedics, neurosurgery, urology, ophthalmology, ENT, maxillofacial and vascular surgery). Disease duration was defined as the time between RA diagnosis and the end of the study (May 2018). Univariable and multivariable analyses were performed (Table). Results: Data from 170 RA patients (77.1% female) with a mean±SD age of: 62.1 ± 13.7 years and disease duration: 87.8 ± 22.0 months, were recorded. The median number of non-rheumatic drugs receieved througouht disease duration was 3. Only 7% of the patients were not receiving any additional drugs, while 15.3%, 40.6% and 56.4% had received 1, 2 and 3 non-rheumatic drugs, respectively. The most commonly used non-rheumatic drugs were, anti-hypertensive, anti-osteoporotic and lipid-lowering drugs. Higher total number of drugs correlated with age of the patient and longer disease duration. Methotrexate (MTX) experienced or biologic-naïve patinets, had received a larger number of non-rheumatic drugs compared to those who had not received methotrexate or were biologic-experienced. Multivariable analysis confirmed age and exposure to methotrexate/biologics to be positively and negatively association respectively, with the number of non-rheumatic drugs received (Table). Number of visits to rheumatologists/year were: median (range) 2.9 (0.5 – 13.6). The number of visits was correlated with age of the patients, disease duration and number of non-rheumatic drugs received. Multivariable analysis, identified, disease duration, number of non-rheumatic drugs received and being MTX-naive as predictors of number of rheumatology visits (Table). Number of visits to non-rheumatologists/year were: median (range) 1.8 (0.0 – 13.7). Visits to "internal medicine" doctors were more common than in "surgical specialties" doctors (p<0.0001). Number of visits to non-rheumatologists was correlated with age, disease duration, and with the number of non-rheumatic drugs received. Multivariable analysis confirmed only the association with the total number of drugs but revealed also that being MTX-naive was also associated with more frequent visits to non-rheumatologists. Conclusion: The majority of RA patients received more than 3 (non-RA related) drugs. This increased with older age and associated with more frequent visits to rheumatology and other specialties.Table 1 References [1] Filkova M, et al. J Rheumatol. 2017 Dec;44:1786-1793 Disclosure of Interests: None declared


In order to get the range of particle size in which the measurement result is more accurate and reliable,the wettability of four different kinds of flotation coal,each of which were divided into four size fractions,has been measured by using the contract angle measuring module of K100 surface tension tester.The result shows that the difference in particle wettability affects the effect in particle size on Washburn equation.For Ji' ning coal,which is highly hydrophobic,the particle size has little influence.Ruqigou coal,which is strongly hydrophilic,satisfies the Washburn equation that the relationship of slopes is consistent with the particle size.And for Jiahe and Qianjiaying coal,which are partly hydrophilic,the relationship of slopes differ from the particle sizes.So when the wettability is very strong or very weak the effect of the particle size is very weak and the range of particle size can be relaxed.On the other hand,when the particles are partly hydrophilic,the effect of the particle size is very significant and large particles will affect the accuracy of the experimental results.For different liquid,the law of the particle size effect is different.Take Jiahe coal as an example.The relationship of the slopes for water and Jiahe coal is k0.25~0.125 k0.125~0.074 k0.5~0.25 k0.074~0.038,but for oil and Jiahe coal is k0.125~0.074 k0.25~0.125 k0.5~0.25 k0.074~0.038.And similar situations occure when using other coals.So the influence of particle size can't be removed by using reference liquid.In conventional flotation system,the wettability of particles whose size is less than 0.5 mm can't be measured directly with this method.And to increase the accuracy of measurement,the particle size should better be less than 0.125mm.


Avulsion of permanent teeth is one of the serious injuries that require immediate attention in a dental setup and immediate replantation and splinting is the treatment of choice. The replantation of avulsed tooth improves aesthetics, occlusion, and function. Most common complication of tooth replantation is inflammatory external root resorption. Mineral trioxide aggregate is a calcium silicate-based material that maintains high alkaline pH for a longer duration and it helps in preventing inflammatory external root resorption. The purpose of this article is to report the successful management of inflammatory external root resorption associated with a replanted maxillary right central incisor using MTA in an 11-year-old girl with one-year follow-up.


Governing Federations: Constitution, Politics Resources, edited by MICHAEL WOOD, CHRISXIPHER WILLIAMS, CAMPBELL SHARMAN (Sydney: Hale & Iremonger in association with the Royal Australian Institute of Public Administration, 1989, 281 pp).

Federalism in Canada t Australia: Historical Perspectives 192088, edited by BRUCE W. HODGINS, JOHN J. EDDY, SHELAGH D. GRANT, JAMES STRUTHERS (Peterborough: Frost Centre for Canadian Heritage and Development Studies, Trent University, 1989, 511 PP).

Australian Federalism, edited by BRIAN GALLIGAN (Melbourne: Longman Cheshire, 1989, 278 pp).


Achievement motivation is defined as a way for an individual to develop or demonstrate high ability in two ways: reference to one's own performance or mastery, or reference of oneself relative to others. The purpose of the study was to compare the sports achievement motivation between Kabaddi and volleyball players that take part in inter college sports competitions. For this study the researcher selected twentyfive (25) kabaddi players and twenty-five (25) volleyball players. The subjects were randomly selected for this study, between the age group of 18-28 years and the level of significance 0.05. To measure sports achievement motivation between kabaddi and volleyball male players, a questionnaire developed by Kamlesh (1990) was employed and for statistical analysis and interpretation of data mean, standard deviation and 't' test was conducted. The result shows that there was no significant difference in sports achievement motivation among kabaddi and volleyball players.


Characteristics of nanoparticles controlled by precursor flow rate and reaction temperature in chemical vapor condensation process were interpreted in the view of decisive reaction factors, i.e. supersaturation ratio, concentration of vapor molecule, collision frequency and rate, and residence time, which directly affect the particle size and size distribution in CVC reactor. As results, the increases of precursor flow rate and reaction temperature induced the increase in the average sizes of nanoparticles in CVC reactor by acceleration of coagulation growth due to the increase of collision between vapor molecules and particles. The effects of reaction factors on the characteristics ofnanoparticles were discussed with considering particle formation process in CVC reactor under given process parameters.


Let H=−∂x2+V(x) be a properly defined Schrodinger operator on L2(R) with real potentials of the form V(x)=q(x)+p′(x) (the derivative is understood in the distributional sense) with some p,q∊L2(R). We prove that the absolutely continuous spectrum of H fills (0,∞) which was previously proven by Deift-Killip for V∊L2(R). We also refine the 3/2-Lieb-Thirring inequality.


Aims: This study was aimed to determine the TiO 2 /zeolite photocatalytic activity for removing red Safranin dye form aqueous phase. Materials and Methods: In this study, TiO 2 nanoparticles were produced using sol-gel method and 2.5 ml sol-gel was coated on 1.2222 g of zeolite. X-ray diffraction (XRD) and scanning electron microscopy (SEM) were applied to specify the structure and morphology of TiO 2 nanoparticles. The effect of TiO 2 coating on zeolite, ultraviolet (UV) radiation intensity, initial concentration of dye and the type of photocatalyst substrate (fixed and moving) on photocatalytic process was investigated. Results: According to XRD results, the TiO 2 nanoparticles had two phases including anatase (80.5%) and rutile (19.5%). The uniformity of nanoparticles was obvious in the SEM images. The removal efficiency of TiO 2 coated on zeolite was higher than TiO 2 photocatalysis with increasing UV radiation intensity from 2.4 w/m 2 to 3.9 w/m 2 , the photocatalytic efficiency was also enhanced. The removal efficiency decreased from 91.61% to 77.91% by increasing the red Safranin dye concentration from 10 mg/L to 50 mg/L. The moving bed of TiO 2 /zeolite photocatalyst had a higher efficiency than the fixed bed. Conclusion: In over all, the TiO 2 /zeolite photocatalyst was much more effective than TiO 2 photocatalyst for Safranin dye removal from the aqueous phase. With increasing UV radiation intensity and decreasing dye concentration photocatalytic efficiency, was improved. TiO 2 /zeolite photocatalyst with fixed bed is recommended to be used in water treatment. The most important problem of using moving-bed TiO 2 /zeolite photocatalyst in the water treatment is opacity.


【This study was carried out the group communication program which I had composed of using the Satir's communication family theory and skills. The purpose of this study was to investigate the effects on the dysfunctional communication self-esteem and depression, executed this program for the mothers group with caring the mental disorders. and then for the test of some hypotheses it was devided two groups ; the experimental group(n=20) and control group(n=25). In the control group they were learned two session family education program in the psychiatric clinics of Pusan National University Hospital and in the experimental group they had experienced during the 10 session by the group communication program. In the methods of the statistics on this datas, it was to statistics X²test for the comparison between the experimental group and control group with general characteristics. The effect of the Group Communication Program was to analyse ANCOVA between pre-post test on the disfunctional communication, self-esteem and depression in the control group and experimental group. The conclusions were derived from the results and test of hypothesis as followings ; 1) The results were tested the differentiation between the experimental and control group, and the pre-post test in the experimental group with dysfunctional communication self-esteem and depression. Some hypothesis were tested and supported as followings : It was supported that the level of dysfunctional communication of the experimental group would be lower than the control group (Hypothesis 1) It was supported that the level of self-esteem of the experimental group would be higher than the control group (Hypothesis 2). It was supported that the level of depression of the experimental group would be lower than the control group (Hypothesis 3). 2) The relation of the dysfunctional communication with the self-esteem was presented negative correlation and with the depression was not correlation. The relation of the self-esteem with the depression was presented significantly negative correlation. The relation of the sacrificuny pattern of dysfuntional communication with the self-esteem was presented negative correlation and with the depression positive correlation.】


Recent research generated information that human milk is not only a valuable source of nutrition, but it also provides a complex microbial community, containing especially Lactobacillus species - the major components of a great number of commercial probiotics. New findings on potential applications of Lactobacillus species revealed that these bacteria have abilities to produce anti-microbial exopolysaccharides (EPS) and to reduce cholesterol in culture broth. In this study, we successfully isolated and screened for Lactobacillus bacteria from human milk samples, and finally obtained four strains, including L. plantarum BM7.13, L. plantarum BM29.7, L. acidophilus BM10.8 and L. rhamnosus BM30.4. Researching the probiotic activities of these strains showed that all strains were tolerant to the low pH (3.0) and 0.3% bile salts. Characterization of the probiotic properties indicated that all selected Lactobacillus isolates had ESP (125-326 mg/L) and exhibited strong antimicrobial activities against pathogenic microbes, such as Escherichia coli, Staphylococcus aureus, Shigella flexneri and Salmonella typhimurium. Our results also indicated that all strains displayed cholesterol assimilation capabilities in culture broth with the maximum figure recorded for L. plantarum BM7.13.


In this paper, we try to build a objective-oriented (teleological) framework for transport planning that could: (i) establish a set of results which have to be sought by the transport sector; (ii) not be mode oriented, thus allowing an inclusive solution approach; and (iii) restrict results to what can be expected from transport planning and practice. This framework starts from classic and commonly accepted objectives as mobility, transport efficacy and efficiency to specify main issues that contribute to each of these aspects. This framework is also a powerful tool for designing information and decision support systems, structuring a knowledge-base, and on designing strategies on transport improvement in order to deal, among other issues, with the problem of social exclusion. (a) For the covering entry of this conference, please see ITRD abstract no. E215911.


This article is intending to analyze several risks of the unsistainable development in tourism industry in Vietnam. Vietnam's tourism sector is booming and contributing signi ficantly to the national economy. Thus, the tourism sustainable development is important for sustainable development in the national economy. The risks of tacking or loosing sustainability in tourism industry will greatly damage the whole economy of Vietnam.


A simple spectrophotometric method has been developed for the determination of Osmium (IV) by using Schiff base 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP]. HPIMNP extracts Os (IV) quantitatively (99.94%) into iso-amyl alcohol from an aqueous solution of pH range 0.0–2.0. The iso-amyl alcohol extracts show maximum absorption at 545 nm (λ max). Beer's Law is obeyed over the Os (IV) concentration range of 1.5 to 24.0 μg/ml. The Molar absorptivity and Sandell's sensitivity for Os-HPIMNP system is 3700.00L mole−1 cm −1 and 0.051μg.cm−2 respectively. The composition of extracted species is found to be 1: 3 [Os-HPIMNP] by Job's continuous variation and Mole-ratio method. Interference by various ions has been studied. The proposed method is rapid, sensitive, reproducible and accurate and it has been satisfactory applied for determination of Osmium (IV) in Synthetic mixture samples.


Purpose In this presentation an overview will be given on the basic optical effects connected with the tear film. A prominent role of the tear film is to create a smooth surface for the most powerful refractive interface of the eye, i.e. the air-cornea interface. On the other hand, the tear film itself can disturb proper imaging if light is scattered in it, or if its surface is not perfectly smooth.

Methods Surface effects on optical image formation can be described with aberrometry. Only, in the case of the epithelial surface, present aberrometers do not have sufficient resolution to describe the fine irregularities. The group of Thibos designed a way to address this problem using the shape of the spot images of the Shack-Hartmann aberrometer. Effects of light scattering can be assessed using straylight measurement (implemented in the C-Quant from Oculus).

Results Both aberrometric and straylight outcomes combine to form the ocular point-spread-function defining the functional problem originating from optical defects in the tear film. The aberrometric errors dominate the central part of the PSF, and thus visual acuity. Straylight corresponds to the peripheral part of the PSF, and dominates in complaints like glare and hazy vision. Literature models for both aspects of the optical problems in the eye media were used to delineate their effects on the PSF.

Conclusion Two domains must be differentiated: the aberration domain and the small particle scatter domain, with corresponding parts (small angle vs large angle) to the PSF. Straylight typically originates ffrom small particles, as opposed to aberrations originating from refractile humps and bumps extending over large distances (tear film surface) or small small distances (epithelial surface).

Commercial interest


a "Southerner," then defines what she means by that term. She speaks as a black female native of a region with a turbulent and violent racial past, a history of white supremacy and bloody racial conflict. Her conclusions, a mixture of experience and hope, recognize the changes that have occurred in her native region, the racial tensions that remain, and the hope for a better tomorrow. The sentiments Harris expresses, perhaps, can best be understood by fellow southerners. Summer Snow provides an opportunity to explore that possibility. ........................................................................................................................


Abstract Introduction: Although paragangliomas (PG) are derived from extra-adrenal chromaffin cells of sympathetic paravertebral ganglia in the thorax, abdomen, and pelvis, they can also arise from parasympathetic ganglia located along the glossopharyngeal and vagal nerves in the neck and at the base of the skull. Non-secretory PG have a low prevalence, are often silent, and can present as a malignant tumor with mass effects. Symptoms often include: unilateral hearing loss, pulsatile tinnitus, cough, hoarseness, pharyngeal fullness, swallowing difficulty, pain, and/or problems with tongue motion. Case: A 25 year old African American woman presented with 2 yrs of exertional presyncope, night sweats, subjective fevers, 20 lb. weight loss and a nontender enlarging left neck mass. Family history: Mother had thyroid cancer. Physical exam- BMI 21 kg/m2, BP 118/72 mmHg, HR 74, with indurated, fixed, nontender mass in left upper neck, inferior to mandibular angle. Laboratory-Hgb 6.9 g/dl, MCV 71.7, Iron 137 mcg/dl, TIBC 151 mcg/dl, Ferritin 155 ng/ml, CRP 65.20 mg/dl, ESR 122 mm/hr, AST 107 U/l, ALT 7 U/L, Alk Phos 81 U/l. EGD and Colonoscopy-normal. CT scan of neck, abdomen and pelvis: 6.0x3.5x2.7 cm heterogeneously enhancing mass in left neck involving skull base at carotid canal level, within the internal carotid space, causing external compression of left internal jugular vein, with multiple hypervascular lesions in bilateral lungs, liver and spleen, as well as cervical, thoracic, lumbar and sacral spine. Packed red blood cells were transfused. Liver Biopsy-metastatic paraganglioma with SDHB mutation. Laboratory tests- normal plasma catecholamines, thyroid function tests, prolactin, cortisol, ACTH, LH, FSH. A few weeks later, she reported new onset left sided tinnitus, orbital pain and vision changes. MRI Brain/orbit- 10 x 11 mm enhancing lesion centered in left cavernous sinus near orbital apex without intra or extraconal lesion. Chemotherapy was started with vincristine, cyclophosphamide and dacarbazine. After 12 weeks of chemotherapy, the left neck mass size decreased, tinnitus, and vision changes resolved. She was referred for genetic counseling and multidisciplinary care. Discussion: Our patient had malignant head and neck PG with SDHB mutation. Mutations in the gene encoding SDH subunit B (SDHB) can lead to metastatic disease in ≥ 40% of patients, are frequently familial, and are associated with other malignancies (renal cell carcinoma, pituitary adenoma, breast and thyroid cancer). Although there are current guidelines regarding diagnosis and management of non-malignant secretory paraganglioma/pheochromocytoma, screening and management of metastatic disease is not clear. Therefore, it is important to have a low threshold of suspicion for early diagnosis. Provider awareness and education regarding diagnosis and management is needed.


To identify the fittest quantity for every higher education resources in Heilongjiang province, a surface model is constructed based on collected data in 20 years, 15 vectors and the corresponding multinomial equation. Firstly, the vectors are integrated to human capital, material capital, intellectual capital and intangible capital, which have been reconstructed from the original data. Considering the performance of teaching and studying respectively, an integrated one is get to make the dependence variable, and the corresponding parameters are get by least square method. At last, joint analyzing the factual situation of Heilongjiang Province's high education resource, the fittest resources are adjusted from the quantity get by the model.


Parking is one place that needed by the community, with a large number of vehicles coming in a market, shops, or elsewhere. This requires proper settings for user convenience and rapid ser- vice more secure parking. Recording transactions in a way perceived less ecient manual and time consuming than if we use the computer facilities. Recording the number of vehicles, calculation of the length of time a vehicle in the parking area and parking fee calculations using computer applications has the bene t that is unbelievably great that no longer waste time in the transaction process.


A class of circuits to decompress matrixes with piecewise redundant rows is presented. A typical application is the use for cyclic redundancy check calculation with programmable polynomials. The decompression is carried out in a small number of clock cycles, and therefore improves performance as well as economises on memory space for storage of the matrixes.


Triclinic, P1, a=8.435, b=8.9898, c=7.8747A, α=106.374, β=96.184, γ=72.64°, Z=1, R=0.038. The molecule lies on a centre of symmetry. The second half of the molecule is generated by symmetry operation 2-x, 1-y, 1-z. However, there is a statistical disorder of hydrogen atoms bonded to C15


International Center for Hydrogen Energy Technologies (ICHET) has been implementing measures to demonstrate potential benefits of the "hydrogen and fuel cell systems" in developing countries. As part of applied R&D activities, various prototype vehicles (a small tri-wheel scooter, a four-passenger cart integrated with a 2 kW fuel cell, a mobile caravan with wind, solar and fuel cell power and a forklift with the necessary fuelling options and controls) were demonstrated utilizing hydrogen as fuel. Performance analysis, sizing of the various system components and modelling will be carried out as part of applied R&D program. A long-term objective of the projects is to push for use of fuel cell powered light mobile vehicles in public places and encourage local industry to manufacturer similar vehicles and explore market potential for such use. As a benefit of this activity, public awareness on applications of renewable and fuel cell technologies will increase and viability of such systems will be demonstrated to change public perception.


The goal of this paper is to review the publication story of Nogeoldae(老乞大) and Bakthonasa(朴通事), Chinese interpretation and conversation textbooks, and their history of changes placing main focus on original Nogeoldae that was retrieved and introduced to the academia recently. At present, various editions of Nogeoldae can be classified into following four types depending on nature and editors or interpreters of the respective work: 1. Original Nogeoldae(原本老乞大) compiled in the end of Koryo dynasty), 2. The Revised Nogeoldae(刪改老乞大) by Ke ̄ gi(葛貴) in 1483 A.D., 3. The Newly Interpreted Nogeoldae(老乞大新釋) by Kim, Changjo(金昌祚) and Byeon, Heon(邊憲) in 1761 A.D., 4. The Republished Nogeoldae(重刊老乞大) by Yi, Su(李洙) in 1795 Similar classification applies to original Bakthongsa(Interpreter Bak), and it is as follows: 1. Original Bakthongsa(原本朴通事, non-existing), 2. Revised Bakthongsa(刪改朴通事), 3. The Newly Interpreted Bakthongsa(朴通事新釋). All of the above were translated into Hangeul to be published as Translated Nogeoldae(飜譯老乞大), Hangeul Nogeoldae(老乞大諺解), Hangeul version of The Newly Interpreted Nogeoldae(新釋老乞大諺解), and Hangeul version of The Republished Nogeoldae(重刊老乞大諺解) on one hand, and Bakthongsa Translated(飜譯朴通事), Hangeul Bakthongsa(朴通事諺解), and Hangeul version of The Reinterpreted Bakthongsa(朴通事新釋諺解). In this paper, we review the current status of these material and their bibliographical features.


Length at age, length at maturity. and age at maturity of yellowfin sole, Pleuronectes asper, in the eastern Bering Sea, are influenced by area of sampling and bottom depth. Yellowfin sole sampled during spring and summer bottom trawl surveys (1982-94) grew faster in the northwest area compared with the southeast area. Mean lengths at age were generally more than 2 cm greater than those for southeast fish at ages greater than 10 years. Length at 50% maturity in females during 1993 and 1994 was respectively 2.3 em and 0.94 cm larger in the northwest area than in the southeast area. In contrast, there was no apparent difference in age at 50% maturity between areas. Spring-summer patterns in bathymetric habitation of yellowfin sole differ for immature and mature individuals and cause a potential bias in estimates of growth and maturity. There is a clear relation between length and depth for immature fish, with older, immature fish inhabiting deeper water. In contrast, mature fish distribute similarly by size across a wide range ofbottom depths. As a result, estimates of length and age at 50% maturity (L5o' A50, tended to increase with increasing bottom depth. Because current resource assessment surveys do not sample the shallowest areas of the summer distribution ofyellowfin sole, estimates ofL5o and ~o are inherently biased high. Manuscript accepted 27 February 1997. Fishery Bulletin 95:494-503 (1997). Yellowfin sole, Pleuronectes asper, inhabit the nearshore shelfareas of the eastern Bering Sea, from Bristol Bay to north of Nunivak Island (600N lat.)(Fig. 1), during spring and summer months. Adult individuals overwinter near the shelfslope break at approximately 200 m. Two main eastern Bering Sea overwintering groups, composed mainly ofsexually mature adults tKrivobok and Tarkovskaya, 1964) have been identified: a southern complex near Unimak Island and a central complex located west of the Pribilof Islands tFadeev, 1970; Bakkala, 1981; Wakabayashi, 1989). During spring, as the edge of the shelf ice recedes toward the coast, yellowfin sole migrate across the shelf to nearshore spawning areas in Bristol Bay and off Nunivak Island CBakkala, 1981). Yellowfin sole generally spawn at bottom depths less than 50 m (Wilderbuer et al., 1992); most spawning activity, however, occurs at depths less than 30 m, May through August (Nichol, 1995). Juvenile yellowfin sole probably do not undergo the long cross-shelf migration. At least some juveniles «6 years) are known to overwinter nearshore (Fadeev, 1970; Wilderbuer et al., 1992), whereas relatively few juveniles overwinter offshore (Krivobok and Tarkovskaya, 1964; Fadeev, 1970>. Bottom trawl surveys for groundfish resource assessment are conducted annually in the eastern Bering Sea to obtain abundance estimates of commercially important fish and invertebrate species. Differences in fish distributions and oceanographic factors have prompted scientists who analyze survey results to stratifY the eastern Bering Sea into discrete northwest and southeast areas, and three different depth regimes (Walters and McPhail, 1982; Walters, 1983; Wakabayashi, 1989; Bakkala, 1993). Thus, both geographic and bathymetric factors affect fish distribution and abundance in the eastern Bering Sea. In this paper I describe regional differences in growth ofyellowfin sole (P. asper) from the eastern Bering Sea and effects of geographic area and bottom depth on estimates of length and age at maturity. Commercial catch records (Norris et al. l ) indicate that yellowfin sole occur in substantial numbers in waters shallower than 30 m, where 1 Norris, J. G., J. D. Berger, and K. T. Black. 1991. Fisherman's guide to catch per unit effort and bycatch data from the National Marine Fisheries Service Observer Program: Bering SealAleutian Island yellowfin sole trawl fishery.AFSC Proc. Rep. NOAA-NMFS 91-07,200 p. Alaska Fisheries Science Center, Natl. Mar. Fish. Serv.• NOAA, 7600 Sand Point Way NE, Seattle, WA 98115-0070. Nichol: Effects of geography and bathymetry on growth and maturity of Pleuronectes asper 495 _---------.........------'---~-........-r__-~--_;_ 64 OON ~~AWRENCE I. ~' ~ 'Y fi.~/ ); ~dk ALASI *' f \ + + + + + + + + +/+ +'-d: + + + + + + + + ill + +~ (-. ...... +"..+ +++++++++.'~ ......+~ ... T +.?+.. ~ . research surveys are not routinely carried out. Thus, current survey biomass estimates underestimate population abundance of the species; exclusion ofjuveniles in shallow water, as well as sexually mature yellowfin sole that inhabit these nearshore spawning areas during the survey period (June-August), may introduce a samplingbias into estimates of growth and estimates of size at maturation. 1b determine the extent of this potential problem, I considered the effects of bottom depth on fish size. Materials and methods 'SO OOW '77 0


(57) about Abstract] protocol to optimize the use of the coded transmission, such as via a wireless link. In this technique, the inter-frame is first, according to the transmission characteristics of the radio channels are divided into segments selected to the optimum size. Each segment is assigned a position identifier and redundancy check sum. Then each segment is assembled to the block, the redundant bits are generated forward error correction algorithm is applied to the block. Then FEC block is divided between valid communication channel, it is transmitted to the receiver. Inverse process is applied to the receiver. Use of this method, it is necessary to apply only to the segment containing the error data. Therefore, simultaneously when using a large block size required for forward error correction performance, the latency required to retransmit the entire block when you can not recover the error to a minimum.


This article mainly introduces the welding procedure test and welding procedure qualification test of compound steel2.25Cr-1Mo and stainless steel,illuminates the availability of welding procedure for compound2.25Cr-1Mo and steel stainless steel.The prac tice proves that the welding process can meet the requirement.


Venous thromboembolism (VTE) is the third most prevalent acute cardiovascular syndrome, behind myocardial infarction and stroke, and is associated with a significant disease burden [1]. Approximately 900 K cases of VTE/year occur in the U.S. There is an estimated death count of about 60–100 K people per year in the U.S. Up to 25% of Pulmonary Embolism cases may present with sudden death [2,3] Serious nonfatal sequelae may occur in up to 50% of patients. These include chronic thromboembolic pulmonary hypertension, post-thrombotic syndrome, and the post-PE syndrome with functional and exercise limitations. There is also a higher risk of MI and stroke in VTE patients [4]. With growing population and longer life expectancy, it is expected that the prevalence of this disorder will increase. Over the past decade there have been several advances in this arena. Most notably in 2012 DOACs (Direct acting oral anticoagulants) were approved for treatment of DVT and PE. Since approval of these oral agents, many patients with DVT are no longer being admitted to the hospital. There is also the potential to discharge low risk pulmonary embolism cases from the emergency department. Also with new diagnostic algorithms the number of CTA (CT angiogram) tests ordered to rule out pulmonary embolism have been reduced [5]. Another important advance has been the use of extended (indefinite) anticoagulation in patients with idiopathic VTE. If unprovoked VTE patients are to be anticoagulated indefinitely then the need for thrombophilic testing for mutations such as Factor V Leiden and Prothrombin Gene 202010A will be reduced. Up until recently oncology patients with VTE have been treated with parenteral low molecular weight heparin. But new data is showing the DOACs are equally effective thus improving the quality of life of these patients in no small part by relieving them of the need for painful daily injections [6,7]. Also DOACs seem to have a role in VTE prophylaxis in these high risk people [8,9]. Finally, in 2020 a new clotting disorder has developed in the form of COVID-19. This is especially significant in the ICU population where a 31% incidence of thrombotic complications has been reported even in the face of standard VTE prophylaxis [10]. The purpose of this issue will be to discuss nine different issues regarding the arena of VTE. These papers written by an international faculty will focus on the current thoughts pertaining to the diagnosis and treatment of VTE. The following topics will be included in this issue:


The present invention relates to a credit document for the composition. The compositions of the present invention as preferably before drying liquid or paste shape, is to include a reversible machine luminescent compound having a colorless print matrix, and the following general formula A: In the formula: - Ar is an n number of the benzene rings represent a single or a plurality of fusion resulting monosubstituted polycyclic aromatic hydrocarbon, wherein n is 4 to 10, - n1 is 0-10, n2 is from 0 to 10 provided that, n1 and If n2 are simultaneously 0 is excluded, and, - Y is especially cyano, trifluoromethyl, formyl, ester, nitro, halo, sulfoxide, sulfonyl, Tricia noete carbonyl, ammonium and phosphonium organic or selected from nyumgi heteroaryl - an organic group.


The cave sediment is a product of karstification.The seasonal variation of karstification has greatly impacted on the precipitation rate and feature of sediment.Selected hydrochemical indictors in the groundwater,the precipitation rate of the cave sediment and carbon dioxide concentration in the case of Xueyu Cave,Chongqing were monitored during Feb.2007 to Sep.2011.Results show that the bicarbonate and calcium concentrations are the main components of the total ions in the groundwater with a ratio of 84.2%~94.4%.It demonstrates the chemical components are controlled by karstfication of the covered bedrock of the carbonate,and the hydrochemical faces are Ca2+-.Compared to other karst areas in SW China,the better overlaying vegetation,more dead branches and leaves,soft ground and developed rock crack in the study area enable the karstification to be stronger in rainy season than that in dry season.The conductivity and concentrations of calcium and bicarbonate in rainy season were 20.1%,29.9% and 16.5% higher than that observed in dry season,respectively.In additional,due to the abundant water source during the rainy season in the performance of increase in drip water,the precipitation rate in rainy season is 82.5% higher than that in dry season.The sediments can not be easily weathered and their color remains white like jade,which is caused by stable temperature,saturated humidity and high carbon dioxide concentration in the cave causes.


This article critically evaluates recent claims about the positive role that corporate social responsibility (CSR) could play in contributing to international development goals such as poverty alleviation and health improvements.
The article suggests that many recent claims about the positive contribution of CSR to international development are unjustified based on four arguments: (1) lack of empirical evidence; (2) analytical limitations of CSR; (3) the constraints of the business case for CSR; and (4) unresolved governance questions.
On the one hand, the article implies that private firms are unlikely to act as successful development actors without corporate governance reforms, which would align the interests of non-traditional stakeholders with corporate interests. On the other hand, the article implies that international development priorities may misalign the intrinsic interests of shareholders and company executives.
The current CSR agenda seems inappropriate for addressing international development goals.


Results of study of stresses induced in pipes buried in field in expansive clay and exposed to seasonal changes, as well as irrigation; asbestos cement pipes were tested to determine stresses at various sections; measurements of soil moisture changes and soil movements; high stresses resulted in pipe through inequalities in lateral and vertical swelling behavior of clay; these stresses could be greater than those caused by internal pressure.


Channel morphology controls on the spatial variation of trace metals in bed sediments are examined in a 500 m reach of Soda Butte Creek, Montana. Sampling by a channel morphology classification system is used to determine the variation in trace metals between morphologic units, laterally and longitudinally within units, and to assess whether channel hydraulics and differential transport of sediments control trace metal distributions. The types of morphologic units sampled are low gradient riffles, high gradient riffles, glides, backwater pools, lateral scour pools, attached bars and detached bars. Ten of each type of morphologic unit were sampled. Three to nine samples were collected from each of these 10 riffles, bars, pools, and glides. Nine of 12 trace metals show significantly different concentrations in sediments smaller than 2 mm when stratified by morphologic units. Backwater pools and attached bars consistently have the highest metal concentrations, while low gradient and high gradient riffles typically have the lowest concentrations. Metals showing the greatest between unit variability are Fe, Cu, Cr, and Al, followed by Ti, Co, Ni, Mg, and V. Lateral and longitudinal variations of metals within units are not significant, and distance downstream does not show a significant linear relationship with metal concentrations. Sediment samples generally contain less than 1% organic matter. Organic content variation between morphologic units is smaller than variability due to analytical error. Higher metal levels in backwater pools and attached bars may be related to the tendency for metals to concentrate in finer sediments, while relatively high levels of some metals in high-gradient riffles may be related to the mineralogy and density of the sediments. Channel bed morphology is a useful scale at which to examine trace metal variation, and is a starting point from which to determine hydraulic parameters which control trace metal concentrations in sediments.


In this article, the critical behavior of birth-death equation for trimolecular reactionmodel has been discussed. If 1+k 3 A 2 3 D 1 )/D 2 ) 1/2 ] 2 , it is just the critical behaviorof the trimolecular model itself. The amplitudes of the unstable fluctuation waves have been taken as order parameters describing the change of fluctuation distribution near the critical point (B=B m ). By using the renormalization method to evade the difficulty due to the divergence of the fluctuation of steady solution at B m , we obtain the generalized Landau-Ginzburg equations for the amplitudes of average values and fluctuation of partical numbers.The analytical and numerical analysis show that, as B increases beyond B m , the variance also has a periodical stable part, the amplitude of which is very large and determined mainly by the saturated amplitudes of average particle numbers.


Recent years have witnessed a proliferation of interest in the phenomenon of the gang both in the UK and across Europe. Such concern has been driven forward by growing reports of gang activity reported in the media, circulated by populist politicians as well as by academic researchers convinced the European gang has been ignored for too long. This anxiety has coalesced in a perception that the gang is a serious and growing problem, that the rise in lethal violence, as seen recently in inner cities such as London, Birmingham, Manchester and Liverpool, is connected to the proliferation of the gang, and that the solution to the problem of urban gang violence lies in its suppression. This article takes a critical standpoint against these statements and challenges attempts to interpret urban violence in the UK as a problem of gangs or a burgeoning gang culture. It argues that the problem of street-based violence is not always reducible to the gang and suggests that the solution to preventing urban violence will not be found by sanctioning crackdowns or gang suppression programmes. It concludes by offering an alternate perception of the gang and urban violence and signposts areas that research on urban violence might need to address.


Abstract The nutrient status of a 6-year-old Norway spruce stand in south-west Sweden was examined 4 and 5 years after application of soil ameliorative treatments. In addition to control plots, three treatments were tested: granulated wood ash at 4150 kg dry weight (dw) ha−1, a nitrogen-free, dolomite-based vitality fertilizer (SkogVital) at 2×1500 kg ha−1 and the fine fraction of harvest residues (mostly needles) at 15,050 kg dw ha−1. The treatments had no short-term effect on height increment. Nitrogen (N) was probably the growth-limiting element, but phosphorus (P) and potassium (K) were also in suboptimum supply. The vitality fertilizer increased the foliar concentration (or the element/N ratio) of P, calcium (Ca) and zinc, while ash application increased the foliar Ca/N ratio. The vitality fertilizer also increased magnesium and Ca concentrations in roots and decreased aluminium concentrations, whereas logging residues and wood ash only increased manganese concentrations in roots. Thus, the vitality fertilizer had a more marked effect on tree nutrient status than the granulated wood ash.


Technology is having a dramatic effect on colleges and universities, producing what may be the most challenging period in the history of higher education. One form of the convergence of technology and education is distributed learning. The World Wide Web (WWW) provides alternative means for delivery of the courses and services, providing learners with an extraordinary range of options. Distance learning methods are being developed and implemented to offer educational opportunities to those who are unable or choose not to attend an educational institution on a conventional, scheduled basis. There are few, if any, studies that have attempted to evaluate the learning achieved through interactivity of students with the online contents using interactive multimedia in online environments, perhaps because of the difficulties in designing rich multimedia contents, a tight experiment for such studies and the fact that confounding variables can easily become significant. The purpose of this study would be to investigate the effectiveness of learning through interactive multimedia and present the results. This research report provides information on the design and development of an online Computational Method in Engineering Technology course. The course is interactive multimedia-based including 3D animation, simulation, video, graphics, and audio. The research considers information on the theoretical framework for designing the course, the process of developing the multimedia and developing the course. The results of the study on the effectiveness of the course is reported in the presentation. Major points of emphasis studied in this research include: 1. Discussing the need for multimedia-rich courses for teaching technology-based subjects in online environments; 2. Developing multimedia based online courses; 3. The effects of using multimedia in teaching technology-based concepts; 4. The results of the study on the effects of using multimedia in an online environment and 5. Results of student attitudes toward learning through multimedia.


1. An apparatus including a vertical double suction pump comprising: a pump housing, the pump housing having a wall; ikoleso with double inlet, located in the pump housing on the shaft and having upper and lower bands with metallic rims, adapted to the formation of the upper and lower insulating annular gap between wheel with double suction and the wall of the pump housing to prevent exposure of the recycle stream from the bleed wheel opening the upper and lower bands and create a controlled axial impact load on the basis of the hydraulic pressure differential on the upper and lower ba ndazhi.2. The apparatus of claim 1, wherein the upper and lower insulating annular gaps are geometrically different between the upper and lower shrouds wheels with double inlet, which creates a pressure drop in the direction parallel to the axis of rotation with a bilateral vsasyvaniem.3. The apparatus according to claim 2, wherein the upper and lower insulating annular gaps adapted to generate controlled axial impact load on the wheel with double inlet, generally not having significant hydraulic head in the direction vrascheniya.4 axis. The apparatus of claim 1, wherein the rims are made of metal to be positioned at a minimum value relative to the outer diameter landing wheels with bilateral vsasyvaniem.5. The apparatus of claim 1, wherein the upper and lower insulating annular or circular clearances are adapted to the formation of the upper or lower bands isolated section extending at least partially into


Absorption spectra of bone samples, and in turn bone tissue composition, were estimated from time-resolved spectroscopy combined with a model of light propagation in small volumes. Bone optical properties show significant correlation with biological properties.


(1) University of Milano-Bicocca, Department of Earth and Environmental Sciences, Italy (email@example.com), (2) Istituto Nazionale di Geofisica e Vulcanologia, CNT, Genova, Italy (email@example.com), (3) Univ. Grenoble Alpes, Univ. Savoie Mont-Blanc, CNRS, IRD, IFSTTAR, ISTerre, Grenoble, France, (4) Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, China, (5) Istituto Nazionale di Geofisica e Vulcanologia, Bologna, Italy


Ascorbic acid is commonly known as vitamin C. By de nition, vitamins, with the exception of vitamin D, are substances which can not be synthesized but are essential for the organism. In this light vitamin C is special. It is hypothesized that millions of years ago some species, like primates, guinea pigs and fruit bats, lost the ability to synthesize ascorbate from glucose due to an inactivation of an enzyme called L-gulono-γ-lactone oxidase. Since then, these species have been dependent on dietary intake of this micronutrient. Ascorbate is not only the most e cient watersoluble antioxidant, but also an important cofactor in neuro-transmitter or collagen biosynthesis. An inadequate intake of this vitamin leads to scurvy. In 2008, a French researcher documented that all species that lost the ability to synthesize ascorbic acid express a di erent facilitative glucose transporter isoform (GLUT) in their erythrocytes. The expressed GLUT-1 transports not only glucose but also dehydroascorbate which is the oxidized form of vitamin C. Was that di erent GLUT expression the keystone event for the evolutionary success of these species? To examine the questions regarding the evolutionary bene t of this transporter expression, the kinetics of ascorbate and dehydroascorbate transport into erythrocytes from four di erent species were evaluated. Further recycling and disposal of the transported vitamin as well as a possible accumulation were observed. The results demonstrate that there are three di erent transport types of dehydroascorbate. One which does not transport the vitamin at all, one whose transport of dehydroascorbate competes with glucose and one which absorbs dehydroascorbate completely independent of the extracellular glucose concentration. After absorption, vitamin C is not recycled and is not disposed back into the extracellular uid. Additionally, it is not stored in the cell until the erythrocyte undergoes apoptosis. The evolutionary bene t is found in an electron transfer across the erythrocyte membrane from intracellular ascorbate to the extracellular, oxidized form of vitamin C. In an energetic light, this recycling of extracellular Vitamin C is more e cient than the de novo synthesis of the micronutrient. Therefore, the erythrocyte acts not as a reservoir for Vitamin C storage, but as a reservoir for electron storage to prevent degradation and loss of dehydroascorbate in times of high oxidative stress. This electron reservoir becomes more important in diseases with high levels of oxidative stress. A metabolic disorder, which is frequently described to be accompanied by high levels of oxidative stress and lowered vitamin C levels in plasma and cells, is diabetes mellitus. The decreased plasma concentrations do not result from a smaller dietary intake. Probably, the uptake of dehydroascorbate into erythrocytes, and, therefore, the extracellular ascorbate recycling is disordered. Investigations of the distribution of GLUT-1 in di erent erythrocyte membrane subdomains showed that the regulation of this transporter is altered in subjects with diabetes mellitus type 1 compared to healthy controls. In vitro no di erences in dehydroascorbate transport rate could be observed but signi cantly decreased intra-erythrocyte vitamin C concentrations were detected in vivo. In conclusion, the altered regulation of GLUT-1 in the erythrocyte membrane in the case of diabetes can a ect vitamin C recycling in plasma. A decreased ascorbate pool in the cells leads to a decreased recycling capacity, and, therefore, to a lower antioxidant defense outside the cell. Due to that knowledge, the recommended dietary intake of vitamin C in the case of diabetes mellitus must be reconsidered to prevent further complications.


Gone are the days when meetings were held in large assembly rooms and preparations were needed to accommodate large number of people. In voluntary organizations' meetings people were compelled to participate in a face to face meeting after a much debated place to hold the meeting. Now participants do not need to worry to go to faraway places to attend the meetings, group discussions, classes, seminars and many other events. Social media have provided opportunities to actively participate in events with the comfort of a home. Social media is having a great impact on the society particularly the educated section of the society. Nursing students and nursing professionals being part of the community are also being influenced by the social media. Use of social media has both advantages and disadvantages and this fact applies equally to the nursing professionals using it. Social media has brought a tremendous revolution in communication and disseminating information to people in all the corners of the world. Social media, a big tool of communication, is increasingly becoming popular with nursing professionals but there is a need to understand that it has to be used cautiously otherwise it may bring a bad name to the nursing profession.


Theintensed sunlight is very important because the amount of energy is very high and intensed in a very small area. In this situation, the heating is a big issue and in order to make safe measurements a remote controlled cyborg is needed. This cyborg will assume the duty of protecting the measured sample and to expose for a precise time to the intensed sun. Also for easy operating, all the duties including the initial conditions, triggering the measurements, and conditioning the signals must be assured by the cyborg.


In this paper, a GC sample introduction technique is described in which an uncoated precolumn and the analytical capillary column are individually temperature programmed. The influence of different rates of temperature programming of the retention gap on band broadening of a series of n-alkanes has been investigated for different lengths of the precolumn. It is shown that extra column band broadening of high boiling solutes is reduced when the temperature of the precolumn is ramped at a faster rate than the analytical column. This benefit is particularly pronounced when long retention gaps are employed.

The technique extends the useful lifetime of the analytical column when complex real-world samples with a wide volatility range are analyzed. This is due to the fact that the final temperature of the precolumn can be kept below the final temperature of the analytical column. Thus, the column is not contaminated with high boiling non-elutable solutes.


A method and apparatus is disclosed for building a tool string uphole of any desired length prior to lowering that tool string downhole into a wellbore for the purpose of performing wellbore operations downhole during a single trip into the wellbore. The apparatus includes a valve 18 disposed between an upper section and a lower section of the wellbore and adapted to open and to close, the upper section of the wellbore being isolated from the lower section of the wellbore when the valve is closed. The tool string of any desired length is built in the upper section of the wellbore when the valve 18 is closed and the upper section of the wellbore is isolated from the lower section of the wellbore. The apparatus also includes a mandrel and piston, the valve being initially disposed in an open position and adapted to be changed from the open position to a closed position when the mandrel is shifted from one position to another position. An upper chamber communicates with a gas reservoir 24 and a valve manifold 26 at the surface. The manifold 26 includes a slow bleed valve and a fast bleed valve. A gas metering orifice separates the upper chamber from a lower chamber. The mandrel is shifted in one direction and the valve changes position when a gas is delivered from the surface of the wellbore to the upper chamber thereby moving the piston and the mandrel, the mandrel shifting in an opposite direction and the valve changing position again when the gas in the upper chamber leaks from the upper chamber to the fast bleed valve at the surface. The mandrel shifts in the one direction and the valve changes position again when the gas from the surface is delivered to the upper chamber. However, the mandrel does not shift in the opposite direction and the valve does not change position again when the gas in the upper chamber leaks from the upper chamber to the slow bleed valve at the surface.


With the streaming media system on computer network more and more extensive application in their daily work and lives, the conflict between network bandwidth and data transfer is also increasingly severe and obvious. If both factors have been fixed, there will be a need to apply the appropriate strategy for network transmission and effective use of the media flow characteristics and network resources to transfer streaming data flow. This article focuses on layered strategy in congestion control strategy. For between each layered strategy there are defects of different priority restrictions and low flexibility, this article brings forward a layered multicast strategy of coding after layer, and gives a detailed test and realization method, and lastly discusses the features of this strategy.


Language-in-education policy is a product of socio-political, cultural, and economic situations, particularly more so in the age of English as a...


In the article the offensive operation of the 40 th army of Voronezh battlefront near Voronezh in September 1942 is under study. On the basis of archival documents and the reminiscences of the fighting participants including information from private archives, the author reveals in detail the objective and preparation for the offensive, covers in a condensed form the course of fighting at the river Don interfluve and on the outskirts of Voronezh, in particular, in the south areas of the city, and summarizes the results of the offensive operation.


Objective To explore the advantages and practical clinical value of combined laparoscopic surgery(CLS).Methods 198 cases who received combined laparoscopic surgery from August 1994 to May 2005 were retrospectively analyzed.Results Of all cases 4 were converted into open surgery,1 case occurred with postoperative fistula of gallbladder,1 case of LC combined laparoscopic common bile duct exploration received postoperative endoscopic sphincterotomy because of residual common bile duct stone,and the other 192 cases acquired success and recovered well.Conclusion As long as strictly following operative indications for CLS,we can treat multiple abdominal diseases safely,effectively and economically,and the patients can be fully benefited from it.


Application of computer management technology,computer optimization technology and manufacture controlling automation technology in a modern clean coalblending factory is illustrated by the design of integrated automation system in Guizhou Tianlong Clean Coal Plant.


The endemics in the floristics is the emphasis contents of the research.First,it systematically discusses the concept,type,origination and studied significance of the endemics in the floristics. Secondary,it overall summarises the studied achievements of the basic condition,life-form,areography,level distribution,vertical distribution and origination of the endemics of the floristics in China.Third,it introduces the research methods of the endemics in floristics by the morphology and geography,the cytogeography and the isozyme analysis. Last,it putts forward to be faced with problem of the endemics of the floristics in China,that the authors think emphasis to study the basic characteristics,formation,origination,evolution and spread of the endemic elements of the three floristic regions of Tian(Yunnan)-Qian(Guizhou)-Gui(Guangxi),Mt.Hengduanshan and Central China and so on.


Bacterial virulence factors are attractive therapeutic targets because they do not affect bacterial growth and thus should be under less selective pressure to develop drug resistance. One drawback, however, is that virulence factors are often species-specific and thus unlikely to be useful as broad-spectrum targets. Researchers at the University of Texas Southwestern Medical Center now have shown that the virulence target QseC is conserved across multiple types of bacteria, and they have identified a QseC inhibitor that could offer broad-spectrum antibacterial efficacy.1 QseC is a membrane-embedded histidine kinase that bacteria use to recognize the host signaling molecules epinephrine and norepinephrine, and bacterial autoinducer-3 (AI-3), a compound involved in bacterial cell-to-cell signaling. Once one of these molecules has been detected, QseC triggers a complex signaling cascade that activates, among other targets, bacterial virulence genes.2 Blocking QseC signaling could prevent a bacterial pathogen from identifying host signaling molecules and thus inhibit the bacteria from recognizing the host environment and becoming virulent. According to the authors of the Science paper, "because QseC is present in many important animal and plant pathogens, drugs that target this sensor kinase have the potential to have broad spectrum." Using a high throughput screen, the UT Southwestern researchers identified LED209, a substituted benzenesulfonamide that inhibits QseC-dependent virulence-gene activation. In cultures of Escherichia coli, Salmonella typhimurium and Francisella tularensis, the small molecule lowered expression of several virulence genes. In mice infected with S. typhimurium, 80% of those given LED209 were alive 24 hours after infection compared with 30% of untreated controls. Additionally, in mice infected with F. tularensis, 80% of treated mice were alive 9 days after infection compared with 10% of untreated controls. Ongoing SAR studies of LED209 are aimed at developing a nonsystemically absorbed form of the molecule to increase its antibacterial efficacy in the gut. Vanessa Sperandio, the principal investigator and corresponding author on the Science paper, told SciBX that "by blocking QseC signaling and preventing bacterial pathogens from knowing where they are, the pathogens aren't able to program themselves to become virulent, and the immune system can simply clear the nonvirulent bacteria." Sperandio added that because histidine kinases are absent in humans, inhibitors of QseC should be sufficiently selective to target bacterial cells without affecting mammalian cells. Sperandio is an associate professor of microbiology at UT Southwestern.


The present invention is a polyurethane and an isocyanate having at least 60% rebound rate relates to thermoplastic polyurethane elastomer by melt spinning the termination polyether or polyester additive obtained fiber. The elastic fibers have a low shrinkage, high heat resistance, low tensile properties and high elongation.


The global data on arsenic (As) contamination in drinking water and the severity of As exposure emphasize the utmost need for early and efficient detection of As in water. In this work, we report a quantitative optical detection of As in drinking water using silver nanoparticle (AgNP) functionalized etched-fiber Bragg grating (e-FBG) sensor. The selective attachment of As (III) to AgNP is applied here for the sensitive detection of As, which is exemplified as a Bragg wavelength shift (<inline-formula> <tex-math notation="LaTeX">$\Delta \lambda _{B}{)}$ </tex-math></inline-formula> in the functionalized e-FBG sensor. The detection limit is found to be 10 femtomolar (fM) with dynamic range up to 100 nanomolar (nm), which is less than the World Health Organization (WHO) standards for drinking water (not over 50.5 nm). The e-FBG sensor shows a good reproducibility (standard error < 10 pm), specificity, and sensitivity (86.13 pm/<inline-formula> <tex-math notation="LaTeX">$10^{-{1}}\cdot \text{M}$ </tex-math></inline-formula>) to As in real time at ambient conditions. The quantitative As value, with a 94% recovery in tap water sample, makes the e-FBG sensor better than the other methods.


The paper describes experimental and numerical investigations of turbine vane clocking effects on the flow process in a two-stage turbine with low-aspect ratio stators. The data present clocking effects that can be observed both for local flow patterns and external characteristics for the entire machine in terms of efficiency. A low-aspect ratio and high turning create a highly three-dimensional flow that is dominated by secondary flows. The aim was to reduce the impact of the secondary flows by bowing the first stator vanes by means of different vane bending and the stator clocking. Another major objective was to show how wake trajectory features can be applied in a turbine design. The changes in the secondary flow structures of the first stator were performed by leaning and bowing the airfoils to achieve load reduction near end walls. This can lead to a weaker end wall secondary flow structures and lower losses. Bowed blades are nowadays often adopted for high-pressure gas and steam turbines. The results demonstrate that incoming interacting streamwise vortices have a major influence on the secondary flows and loss generation mechanisms of the downstream airfoil rows. Using the clocking concept, the secondary flow structures are forced to interact one with another at different positions of the stators. This procedure reveals the best nature of such interactions and shows the resulting benefits. The data acquired by clocking the upstream cascade can identify the effects of incoming vortices, particularly when they entering the leading edge regions of the downstream cascade airfoil. The results for this test indicate that the size and strength of the secondary flows for the downstream cascade should be lower than those obtained without interaction. It is apparent from these investigations that incoming stream-wise vortices may have a potential effect on the flow distribution for downstream airfoil rows. The first part of the paper presents results of the stator clocking identification for different geometries of the first stator. An introduction of the vane bowing has redesigned the first stator. The cylindrical version and two combinations of the bowed vanes with low and high curvature have been considered for the first stator. The authors have found that modified vanes produce smaller and weaker secondary flow structures. The second part presents experimental and numerical results of the clocking investigations for the above-mentioned versions. The experiments have shown that clocking effects seem to be related to the stator wake and vortex structures which produce low momentum fluid areas. These areas interact with boundary layers or secondary flow regions of the second stator where the fluid momentum is already low. Clocking effects on external flow parameter are analyzed versus the low momentum area trajectories due to the first stator vane bowing. The present work focuses on the structures that are formed downstream as a result of the exit flow field of the upstream stage, and examines the implication for efficiency improvement. This paper therefore deals with an interaction of complex three-dimensional stator-rotor flow structures in the two-stage axial turbine.Copyright © 2007 by ASME


Information assurance courses delivered in an online environment pose challenges to the development of meaningful hands-on exercises for students. This article presents techniques on furnishing laboratory exercises to online students and presents examples of assignments drawn from the author's experiences in teaching online courses for over three years. These assignments have proven successful in enhancing the learning experiences of undergraduate and graduate computer science students in introductory and advanced courses in the area of information assurance. Typical courses include introduction to computer networks, computer and network security, information assurance, network management, wireless networks and applications, computer forensics, and risk assessment.


We report here a new record of the giant caviomorph Phoberomys corresponding to a fragmentary mandible from the Monte Salvado area, Peruvian Amazonia (Madre de Dios Department). We describe this specimen and compare it with the material previously attributed to Phoberomys. The mandibular fragment is referred to as Phoberomys sp. Found as float on a bank of the Rio Las Piedras, it has been hypothetically assigned a late Miocene age, due to the local/regional stratigraphic and lithologic context. This specimen constitutes the second record of Phoberomys in Peru. For the first time, the pattern of p4s and lower molars in Phoberomys was analyzed and compared to a large taxonomic sample (in-cluding Paleogene-Recent chinchilloids and other caviomorphs) in order to progress the understanding of the homology of dental structures in this genus. For p4s and lower molars, the position of the protoconid in Phoberomys and other chinchilloids (Drytomomys sp., Potamarchus, Eumegamys, Gyriabrus, Isostylomys, and Tetrastylus) is ambiguous, and as a result we propose two alternative homology hypotheses for these taxa: protoconid within the first and second laminae or within the third lamina on juvenile specimens. The knowledge of a comprehensive ontogenetic sequence in extinct and extant chinchilloids, associated with more complete palaeontological records, would likely allow for a clarification of these homology ambiguities.


There is provided an interface for use in sampling ions in a mass spectrometer, the interface being arranged for receiving a quantity of ions from an ion source and forming more than one ion beam therefrom, each ion beam being directed along a respective desired pathway.


A new technique to encode on QR code and its realization are studied in windows system, and one QR code encoder is developed. It can choose the optimal masking model and version, which is to save coding space to a maximum extent. In this encoding system, not only character, number, Chinese character but also pictures can be encoded. What's more, we can save or print the QR code conveniently. Tests show that the encoding system can encode data fast and accurately, with low CPU utility.


Work in progress. Comments are welcome. Please do not quote without permission from the authors. helped improve previous versions of the paper. We would like to thank the managers of the companies studied for sharing their experiences. The first author would also like to thank The MIT-Japan Program Starr Foundation, the CS Holding Fellowship in International Business, and the Massachusetts Institute of Technology Doctoral Fellowship for the financial support for this study. All errors remain ours.


Diesel or gasoline engine cold cranking is a serious problem for different vehicle operation in northern countries. The engine starting torque is usually provided by an on-board electrochemical battery represented by a lead-acid unit. Modern energy storage devices, such as supercapacitors (SCs), lithium-ion, nickel-cadmium (NiCd) and nickel-metal hydride (NiMH) batteries react differently on low temperatures. Moreover, capacity losses also occur. Considering wide applications of such storage devices in electrical vehicles, their behaviour at low temperatures is of interest. Physical simulation of storage battery cold cranking was carried out using a climate chamber. Lithium-ion, NiCd, NiMH and lead-acid batteries were tested individually and paired with a SC unit to generate a power impulse for engine cranking. A number of experiments (up to five) for each type of storage devices were taken. The best performance results both for direct and hybrid cranking simulation were showed by LiFePO4based and Ni-Cd batteries. The SC module itself showed the best performance, but its specific energy capacity cost is too high to have a large battery system based on SCs only. In this case a combined storage could give enough power to fulfill cranking demands.


This article centers on the potential of instability as an aesthetic as well as a political hermeneutic category, using the example of progressive literature in Austria between 1945 and 1955, during what is referred to as a "freeze" in Cold War discourse. In a bid to discuss the potential of the term instability for interdisciplinary analysis, it suggests that an "unstable equilibrium" (A. Okopenko) among the various aesthetic formations on the literary market in Austria during the first decade after 1945 was directly impacted by an equally unstable equilibrium among ideological positions in the Austrian version of a "transitional society" (Claude Ake).


Aron et al. demonstrated the critical role of right inferior frontal cortex in suppressing an already initiated manual response , yet it is unclear how this inhibitory function is implemented in the motor system. Mink suggested that the basal ganglia and specially the subthalamic nucleus, could play an important role because it suppresses the "direct" fronto-striatal pathway that is activated by response initiation. We want to study the inhibition response during the initiated response performed by Parkinsons disease (PD) patients in order to find the appropriate paradigm for further activation studies using functional magnetic resonance. Two groups were selected: 10 PD patients (without surgical treatment) and a control group (healthy subjects) with similar age and educational level. Subjects performed a computerized test, Stop Signal Task, which examines the motor inhibiton control, measuring the latency of inhibitory process to stop the initiated response. Two arrows, with opposite directions appear at the screen and the subject will press the similar key on the keyboard. First, we calculate the typical reaction time for each subject in the GO condition. Then, the test was conducted, introducing the STOP signal (25% of 500 trials). Results showed differences between groups because the mistakes and reaction time on the GO condition were higher in the PD patients.


It is well known that Freon (CC12F2) and sulfur hexafluo ride (SF6) are gases with strong absorption in the ir. They can be used, for example, for wavelength calibration of spec trometers or scanning radiometers or in atmospheric tracer studies. Many workers also are aware that SF6 has a very strong absorption peak which overlaps the CO2 laser lines near 10.6 μm. The extinction (absorption) of these gases is seldom discussed in the literature of ir applications. Yet these data are of potential importance to workers, for example, in the fields of atmospheric or aerosol spectroscopy. The purpose of this Letter is to present absorption data for these gases in mass absorption coefficients, which can be (for example) compared directly with aerosol extinction coefficients, and to suggest practical applications of these data. The general expression for the mass concentration C (g/m) of an ideal gas at pressure p (mm Hg) is Perkin-Elmer model 21 spectrometer. A sample cell 10 cm long, with KBr windows, was used for the measurements re ported here. Spectra were recorded at SF6 pressures of 762 mm Hg, 25.4 mm Hg, and 1.6 mm Hg. The cell was sealed to exclude atmospheric air. Freon spectra were taken by Carlon at 25°C in a 10-cm cell with NaCl windows. The partial pressure p was 4.2 mm Hg in air at 1-atm total pressure. The sample was aerosol-can propellant identified on its label as dichlorodifluoromethane (CCl2F2) and used as a freezing spray for electronic applica tions without added solutes. Since the value of αλ is highly dependent upon the pressure of a gas sample due to pressure-broadening, the values of SF6 are here reported for three pressures including the lowest given in Ref. 3 (1.6 mm Hg), which yields the maximum values of αλ for these data. For Freon, only one partial pressure was available, taken in air at 1-atm total pressure, and comparative extinction coefficients at different pressures could not be calculated. However, the sample pressure (4.2 mm Hg) was comparable with the lowest SF6 partial pressure used (1.6 mm Hg). Figure 1 summarizes αλ for gas pressures of 762 mm Hg, 25.4 mm Hg, and 1.6 mm Hg of SF6. Figure 2 shows αλ for


Withmore and more importance being attached to communicative competence,both teachers and learners have becomeaware of how essential listening as a language skill is for communication.But traditional listening classes fail to help students become successful and effective listeners both in and out of the classroom.Listening class is a heavyburden to some students.This article aims to have a close look at the problems confronted by teachers;in the meantime,tries to give a brief introduction to two key -features of good listening class:authentic listening material andsound teaching procedures.


The level of the in vitro proliferative response of human peripheral blood mononuclear cells (PBMC) to the OKT3 monoclonal antibody is directly related to the level of monocyte representation in the cell population. The responses to OKT3 stimulation of PBMC obtained from different individual are difficult to interpret due to variable percentage representation of monocytes. To eliminate this problem purified T cells from humans of various ages were incubated with 2 ng/ml OKT3 antibody and 10% purified autologous monocytes. The /sup 3/H-TdR incorporation of 1 x 10/sup 5/ T cells at 72 hrs of culture was 69,939 +/- 6085 (SEM) cpm for young individuals (mean age 35 yrs) and 33,163 +/- 2962 cpm for healthy elderly individuals (mean age 78 yrs). In addition, IL2 receptors were measured using two color fluorescence and flow cytometry with phycoerythrin conjugated anti-IL2 receptor antibody and FITC conjugated OKT11 antibody. The percentage of cells expressing IL2 receptors was 46% for the cells from the young individuals and 23% for cells from old individuals. These results suggest that the age related decline in the proliferative ability of T cells is partially due to a decreased expression of IL2 receptors and that proliferation and IL2 receptor expressionmore » is under the control of monocyte accessory cells.« less


Measurements of the production of atomic and molecular metastable states are performed using a novel frozen solid layer detector. This includes examination of solid CO2 and N2O layers in metastable detection, measurements of N( 2P) production from dissociation of N2, investigations into the suitability of solid neon layers for detection of S( 1D) based on electron-impact dissociation studies of OCS and production of O(1S) and CO(a3Π) in electron-impact dissociation of methanol. Novel solid layers for detection of metastable states were examined to determine which products they were sensitive to. First, CO2 layers were deposited and were found to be sensitive to both O(1S) and N2(a Πg) metastable states. The relative efficiency of these layers as a function of temperature and lifetime of the state formed from the impinging O(1S) atoms are reported. Mechanisms which may be responsible for the radiation through formation of CO3 or its ion are also suggested. The detection of metastable N2(a Πg) states from solid N2O layers is also reported. A study of N(2P) production after electron-impact dissociation of N2 was also performed. It was determined that two excitation channels contribute to production of this state. Time-of-flight and fragment kinetic energy spectra are presented for 100 eV impact energy. Excitation function data is also provided over the 0 eV to 200 eV range for one of these channels. Dissociation processes are proposed for both production channels which appear to be due to both a direct dissociation and pre-dissociation mechanism. Intermediary states are proposed for both channels. Investigations into the suitability of solid neon layers for the detection of S(1D) are performed through studies of electron-impact dissociation of OCS. It was found that while production of S(1D) is likely occurring, interactions with solid neon layers do not result in emission within the optical spectral range of our photo-multiplier tube. However, an ultraviolet emission from these layers was detected in these experiments. While the nature of this feature was not definitively identified, some possible processes which may be responsible are discussed. Future investigations to determine the source of the emission are proposed. In addition, likely production channels of S(1D) are suggested. Electron-impact dissociation of methanol was also performed. It was observed that both CO(a3Π) and O(1S) metastable states are produced and detected with solid xenon layers. While production of CO(a3Π) has been reported previously, this appears to be the


A new regime is found in which the growth rate of the resistive interchange mode in cylindrical geometry is considerably smaller than previously believed. This stabilization is due to coupling to the external, tearing stable, region. Considering the crossover point from the conventional resistive interchange to the new regime as a critical beta, beta sub c, we find beta sub c about 7% for classical resistivity with T sub e = 10 eV, in agreement with recent numerical studies. However, beta sub c scales as T sub e to the -3/5th power, giving beta sub c about 1% for T sub e = 1 keV. Marginally stable pressure profiles for totally localized modes in the Bessel function model for a reversed field pinch are also computed, and show that the central pressure may be up to 400 times the pressure at the wall.


The breaking strength and elongation of netting cord were measured on the test piece of various length and the following results were obtained. 1) The number of yarns composing cotton twine seems not to affect the coefficient of varia-bility of the breaking strength. (Fig. 1) 2) The longer test piece is used, the weaker strength is read. And the breaking strength and elongation is fitted by broken line in relation to the length of test piece, but they remain constant when test piece is long over a definite value depending on the kind of fiber and the construction of cord. (Figs. 1, 2 and 3)


Author(s): Medina, Albert | Advisor(s): Eldredge, Jeff D | Abstract: Flapping flight has gained much attention in the past decade driven by the desire to understand capabilities observed in nature and the desire to develop agile small-scale aerial vehicles. Advancing our current understanding of unsteady aerodynamics is an essential component in the development of micro-air vehicles (MAV) intended to utilize flight mechanics akin to insect flight. Thus the efforts undertaken that of bio-mimicry. The complexities of insect wing motion are dissected and simplified to more tractable problems to elucidate the fundamentals of unsteady aerodynamics in biologically inspired kinematics. The MAV's fruition would satisfy long established needs in both the military and civilian sectors. Although recent studies have provided great insight into the lift generating mechanisms of flapping wings the deflection response of such wings remains poorly understood. This dissertation numerically and experimentally investigates the aerodynamic performance of passively and actively deflected wings in hover and rotary kinematics. Flexibility is distilled to discrete lines of flexion which acknowledging major flexion lines in insect wings to be the primary avenue for deformation. Of primary concern is the development of the leading-edge vortex (LEV), a high circulation region of low pressure above the wing to which much of the wing's lift generation is attributed. Two-dimensional simulations of wings with chord-wise flexibility in a freestream reveal a lift generating mechanism unavailable to rigid wings with origins in vortical symmetry breaking. The inclusion of flexibility in translating wings accelerated from rest revealed the formation time of the initial LEV was very weakly dependent on the flexible stiffness of the wing, maintaining a universal time scale of four to five chords of travel before shedding. The frequency of oscillatory shedding of the leading and trailing-edge vortices that develops after the initial vortex shedding was shown to be responsive to flexibility satisfying an inverse proportionality to stiffness. In hover, an effective pitch angle can be defined in a flexible wing that accounts for deflection which shifts results toward trend lines of rigid wings. Three-dimensional simulations examining the effects of two distinct deformation modes undergoing prescribed deformation associated with root and tip deflection demonstrated a greater aerodynamic response to tip deflection in hover. Efficiency gains in flexion wings over rigid wing counterpart were shown to be dependent on Reynolds number with efficiency in both modes increasing with increased Reynolds number. Additionally, while the leading-edge vortex axis proved insensitive to deformation, the shape and orientation of the LEV core is modified. Experiments on three-dimensional dynamically-scaled fruit fly wings with passive deformation operating in the bursting limit Reynolds number regime revealed enhanced leading-edge vortex bursting with tip deflection promoting greater LEV core flow deceleration in stroke. Experimental studies on rotary wings highlights a universal formation time of the leading-edge vortex independent of Reynolds number, acceleration profile and aspect ratio. Efforts to replicate LEV bursting phenomena of higher aspect ratio wings in a unity aspect ratio wing such that LEV growth is no limited by span but by the LEV traversing the chord revealed a flow regime of oscillatory lift generation reminiscent of behavior exhibited in translating wings that also maintains magnitude peak to peak.


An electronic motor truck scale is provided, which is characterized in that: a bearing platform is configured with smooth and pleasant plane; a sensor mounting hole is provided at two sides of the bearing platform; a junction box mounting hole is positioned under the bearing platform; a longitudinal and a horizontal position limiting device are positioned at two ends of the bearing platform; a ''U-shape'' position limiting baffle that is respectively parallel with the longitudinal and horizontal brims of the bearing platforms and keeps certain distance from the latter is also positioned at two ends of the bearing platform; a middle section scale platform and scale platforms at two ends are joined with formed surface; a lifting ring is positioned in the sensor mounting hole at two sides of the bearing platform. The utility model has the advantages as follows: (1) the bearing platform has smooth plane, which prevents the leakage of rainwater and effectively protects the sensor and the bearing platform form corrosion; (2) convenient installation, debugging and maintenance of the sensor; (3) the overall strength and rigidity are greatly enhanced and the service life are prolonged; (4) the position limiting mechanism has simple structure, can be adjusted via visual observation and ensures accurate position limiting; (5) the scale platforms join with each other via formed surface, thus ensuring convenient installation.


Abstract The results of a transmission electron microscope (TEM) study of both the high- and low-forms of cristobalite as well as of the phase transition between them are presented. Both high- and low-forms are found to exhibit intense, closely related diffuse intensity distributions. The microstructure of the α-(or low-) form includes both tetragonal twin variants as well as a characteristic array of striations corresponding to planar boundaries. Satellite dark field imaging rules out the possibility that these are simple displacement faults.


The reaction of CuCl2·2H2O with the methyl ester of 3,5-dimethyl pyrazole-1-dithioic acid (mdpa) yields a blackish brown complex of composition, [Cu(mdpa)2][CuCl2]. The complex formed a well-defined crystal and is characterized by single-crystal X-ray diffraction, thermogravimetry (TG), and spectroscopic studies. The molecule possesses a distorted tetrahedral configuration with a CuN2S2 chromophore with +1 oxidation state of copper. The TG study reveals that the molecule is a suitable precursor for copper sulfide nanoparticles. The low temperature thermal decomposition of the single-source precursor produces hexagonal chalcocite (Cu2S) nanostructures in ethylene diamine and ethylene glycol. A selective synthesis of copper-rich high chalcocite was obtained using the new precursor. The size and morphology of the synthesized Cu2S nanoparticles are guided by the precursor and likely to be less dependent on the solvent used in the experiment. The nanoparticles were characterized by X-ray diffraction, scanning electronic microscope, and UV-Vis spectroscopic studies. The optical band gap of the as-synthesized Cu2S nanoparticles is measured to be 1.80–2.40 eV. The Cu2S nanoparticles are found to be good catalysts in UV photo catalytic decomposition (90%) of Congo red (CR) dye following first-order reaction kinetics, and the reusability study of the Cu2S catalyst also shows excellent catalytic performance (80%).


The aim is to research Competitive Intelligence (CI) activities in small and medium-sized enterprises (SMEs) in Spain. An attempt is made to analyze the differences existing between exporting and non-exporting firms. To this end, a questionnaire was distributed among 425 firms of the industry, selected from a list of innovative organizations. The results, highlighted significant differences exist between exporting and non-exporting firms in the intensity of CI activities depending on their competitive positioning. An evolution of Spanish SMEs is noted as far as CI activities are concerned, as there are an ever-increasing number of firms that have established formal procedures.


This study investigated 208 students from two schools of social work on their views and experiences with religion and spirituality in education and practice. Results revealed a generally favorable stance toward the role of religion and spirituality in social work practice and relatively high endorsement and utilization of spiritually oriented interventions with clients. These findings are striking given that the majority of respondents reported little exposure to content on religion and spirituality in their educational program, thus raising concern about potential harm to clients. Results from the study are compared with previous research on social work practitioners and faculty, and implications for social work education are presented.


The aim of this paper is to understand how Local Agenda 21 (LA21) is contributing to update local policy and decision making towards sustainable development in Portugal. Departing from a theoretical view of governance for sustainable development – its core values and challenges – and the role of LA21 in its endorsement, the paper presents the main results of a questionnaire survey submitted to Portuguese municipalities, with the purpose of understanding how far LA21 is being incorporated into planning and management. The paper then tries to expose some of the main potential, limitations and challenges in the local Portuguese case for the short-term sustainable future.


We designed a pair of primers to amplify the NA gene of Swine Influenza Virus (SIV) A/Swine/Inner Mongolia/547/01 (SW/IM/547/01) based on the reported gene sequence.The complimentary DNA of NA gene was amplified by RT-PCR and was cloned into pMD18-T vector.The NA gene was subcloned into the transfer vector pMelBacB after being digested with HindⅢ.Then the purified pMelBacNA was co-transfected to log-phase sf9 insect cells with the linear DNA of baculovirus (Bac-N-Blue~(TM) DNA) and Cellfectin reagent.The recombinant baculovirus were purified by three cycles of plaque assay with the chromogenic substrate x-gal in the agarose overlay.After that,the purified recombinant baculovirus was confirmed by PCR that it was not contaminated with field baculovirus.The results of SDS-PAGE indicated that NA gene was expressed successfully in sf9 insect cells.Western blot and NA assay indicated that the NA expressed by recombinant baculovirus in sf9 insect cells has good immunity and biological activity.The research is a good base for development of SIV subunit vaccine and the further study for the function of NA.


The present invention discloses a social network display apparatus selected through the second feedback. Disclose data relating to the behavior of a system and method for publishing data to one or more social networking services, browsing and IPTV user on a particular platform, select and play media from a particular source is tracked so that such representatives feeding behavior may be communicated to the social networking services for publication. Accordingly, in response to the feed, the user, platform, and provide information about the selected media service of the media may be presented on one or more page provided by the social networking service. By special tags embedded in the social network service server shown API supported protocols and methods compatible feeding the data from the feed can and the local social network content the same look and feel and user experience is displayed on the page.


Cancer Focus Northern Ireland is here to help everyone affected by cancer, their families and carers. We have over 40 yearsâ?T experience of supporting people with cancer and during that time weâ?Tve helped men and women, with all types of cancer and, at all stages of illness.


The main objectives of this chapter are: - to place the recruitment and selection process within the wider context of human resource planning and the options organizations have to choose from when vacancies occur; - to evaluate the main approaches used by organizations when recruiting and selecting employees and to critique the underpinning assumptions made by recruiters that inform their decisions; - to examine the relationship between recruitment and selection and HRM, appreciating the importance of these activities to business performance and the attainment of organizational goals.


This paper investigates the instability overflow within stock market and the foreign exchange market in Pakistan. We used GARCH and EGARCH technique for the long term association and the instability overflow is formed. The expected consequences from co-amalgamation examination demonstrate that there is no lasting association connecting the two marketplaces. The consequences from the instability forming demonstrate that the performances of together the stock exchange and the foreign exchange markets are interconnected. The takings of one market are influenced by the instability of the new market. Specifically, the takings of the stock market are responsive to the takings and the instability of the foreign exchange market. Alternatively, takings in the foreign exchange market are denoting relapse which are influenced by the instability of stock market takings. There is a significant association within the instability of the foreign exchange market and the instability of takings in the stock market.


Selkirk Flood Protection Scheme has announced that RJ McLeod has been confirmed as the successful tenderer for the main construction works contract at the end of a major procurement exercise.


Over decades, tourism has grown steadily and has become increasingly diverse, becoming one of the fastest growing economic sectors in the world. Indeed, among all this forms of tourism, emerging geological tourism in recent years is considered as an alternative that can be associated with classical tourism, which constitutes a presentation of the geological and geomorphological heritage of a territory and highlights the Enormous geological and cultural diversity. Our study forms part of the ongoing work on a territorial project which aims the structuring of these resources/territory (what can be done? what happens? Offers, events). The valorization, mobilization and combination of these resources are made to give various forms of geological tourism in a transversal and territorial approach.


Abstract The problem of generating expressive musical performances in the context of tenor saxophone interpretations was studied. Several recordings of a tenor sax playing different Jazz ballads with different degrees of expressiveness including an inexpressive interpretation of each ballad were made. These recordings were analyzed, using Sms spectral modeling techniques, to extract information related to several expressive parameters. This set of parameters and the scores constitute the set of cases (examples) of a case‐based system. From this set of cases, the system infers a set of possible expressive transformations for a given new phrase applying similarity criteria, based on background musical knowledge, between this new phrase and the set of cases. Finally, SaxEx applies the inferred expressive transformations to the new phrase using the synthesis capabilities of Sms.


First,the basic techniques for developing the call processing software are introduced.The software architecture based on Vxworks and the real-time call processing software system are presented.Finite State Machine(FSM)and software framework are studied.Then hierarchical call processing software framework is elicited and the main functions of call control module are introduced.The call control entity is abstracted,the design of parameters of the call control entity is described,and the call control instance is given.At last,the test of call processing software is conducted and the analysis of test results is given.


Abstract The purpose of this study was to examine the relationship between the self-esteem and oral health awareness of college students and influential factors for their oral health awareness in an effort to plan an oral health program tailored to college students. The subjects in this study were 394 students who were in G college and J university in the city of Gwangju, on whom a self-administered survey was conducted. After a survey was conducted, the collected data were analyzed. The findings of the study were as follows: Regarding oral health awareness by general characteristics, the students who had experience of receiving oral health education were better in that regard(p<0.05). As to awareness of oral health education, the health-related majors took the best view of it (p<0.05). Concerning the links between self-esteem and oral health awareness, there was a significant positive correlation between the two. As a result of analyzing what factors affected oral health awareness, oral health awareness was under the significant influence of self-esteem, self-rated oral health status and oral health education(p<0.05). Given the findings of the study, oral health education programs geared toward college students should be developed in consideration of the various influential factors for oral health awareness to offer better education.


The rationality of investment managers' expectations is tested using quantified survey data. The variables examined include expectations of the annual percentage chan ge in the U.K. FTA All Share and U.S. Standard and Poor's composite s tock market indices, and the expected rates of U.K. price and wage in flation. Tests for the orthogonality of forecast errors to both small and large information sets known at the time of the forecast are car ried out, both with and without allowance for measurement errors in t he expectations series. The results decisively reject the rational ex pectations hypothesis as applied to investment managers' expectations . Copyright 1988 by The London School of Economics and Political Science.