Using extract from Flos lonicerae as the main component,the best formula was optimized for course preparation of buccal tablets by comprehensive evaluation index including appearance,taste,disintegration and friability,hardness,weight etc.Implantation of cotton ball into Granuloma of rats induced by tissue hyperplasia was used to assess its function on chronic inflammation.The results showed that the prescriptions with extract of Flos lonicerae(10%),sugar(25%),starch(5%),maltodextrin(15%) and mannitol(45%) were optimum.The inflammation-diminishing test of throat showed significant differences(P0.01) of hyperplasia between inflammatory granulation tissue and control group.The wet weight of animal Granuloma reduced significantly,irrespectively of used dosage of honeysuckle buccal solutions.Therefore,the optimized formula may satisfy the requirements for Flos lonicerae buccal tablet preparation,and the honeysuckle buccal tablets were preliminarily confirmed to be anti-inflammatory.


Results of experimental and theoretical studies have determined which physical parameters of PIN diode junctions control their dynamic responses as limiters to fast-risetime microwave pulses. Both RF and DC dynamic impedance measurements were made and compared, with good agreement, to theoretical calculations which model both the junction and intrinsic regions of the PIN diode. One interesting analytic result is that a low level of p-type doping in the intrinsic region reduces the transient turn-on response time and reduces the turn-on peak voltage. The holes in the intrinsic region help compensate for the lower hole mobility in Si.<<ETX>>


A system and a method are provided for making magnetic recording servo tracks with inherent dropout robustness and with encoded track set information, longitudinal position information and other information recorded during tape or disk manufacture. A tape is provided having at least two servo tracks of opposite polarity recordings separated by a transition region. Servo data signals are produced for recording on the at least two tracks of the tape during a single pass during manufacture of the tape. The servo data signals are derived from MR elements that determine the polarity of the servo data signals.


Traditional indigo print once played an important role in people's daily life and it was the embodiment of plain but implicit beauty.This article proposes several approaches to innovate the color of Nantong traditional indigo print,including precisely controlling the pigmentation by applying modern technology to bring more hues,further developing the technology of overprint to enhance the saturation and using indigoid dye with other vegetable dyes to create more color schemes.All these approaches will help the colors of the traditional indigo print be more vigorous.


This paper addresses the multi-machine multi-item capacitated production planning problem with sequence-dependent changeovers that faced by most process industries. A new mixed-integer programming model formulation and its incorporation into a fix-and-relax heuristic are proposed. Numerical studies from test instances of different size exhibit that the developed heuristic approach is capable of solving large instances within a reasonable amount of time and indicate superior solution qualities.


E-health incorporates a range of digital techniques that are interlinked because they promise to improve people's health and quality of life. The question of how these techniques actually contribute to "living a good live" is not so easy to answer, because scientific, commercial and patients' perspectives all come into play. Research on the unintended consequences of e-health applications clearly shows that it is necessary to anticipate social consequences as early as in the design phase. However, because it is not possible to predict some outcomes, it is also necessary to properly monitor how these techniques affect daily life. It is crucial to pay attention to how these techniques affect people with different educational backgrounds.. Digital techniques have a great capacity to democratise healthcare, but may also unintentionally increase health inequalities. The ethical consequences of e-health applications need to be anticipated and monitored in order to prevent this happening as much as possible.


Abstract : A balloon-borne submicron aerosol counter developed under previous Air Force contracts was successfully flown on three stratospheric balloon experiments over Holloman AFB, New Mexico in May of 1973. The results indicate that particulate matter at higher levels is characterized by markedly different scattering parameters than is the case at lower levels. This effect is manifested in the form of exceedingly sharp cut-offs in the size distribution at about 0.4 micrometer diameter, which is only observed above 23 km. The extent to which this sharp cut-off is attributable either to nonspherical particles or to index of refraction uncertainties rather than to the actual size distribution, is a matter of conjecture. Recommendations for equipment modifications tending to eliminate these ambiguities, are discussed. Also described here are the several hardware and software modifications incorporated in the system under the present contract in preparation for these flights. (Author)


As is known, the concept of care in the philosophy of nursing over the course of the last few decades has been recognized as its most important paradigm. No small part in its theoretical description, defining through this the formal structure of nursing, has been played by the philosophical output of M. Heidegger. It is therefore not surprising whatsoever that the concepts developed by him are often used by many authors who write about care in the philosophy of nursing. However, the fundamental semantic scope of many of Heidegger's terms, even for those who dabble in philosophy ex professo, still remains unclear. Even greater difficulty arises with regard to their meaning in relation to the philosophy of nursing. So to what extent can Heidegger's thought expressed as it is in such a specific language be helpful to cope with the demands of contemporary nursing? On what basis does the uniqueness of his inspiration for the paradigm of care and selecting postulates lie?


A dough pressing system (100) including means for coupling a cover to a pressing platen (110), wherein the cover can reduce the wear caused to the pressing platen (110) by the heat and pressure used to process one or more products. The cover optionally can be configured to be removably attached to the pressing platen (110) with vacuum pressure. One or more spacers (310a-f) are placed between the cover and the pressing platen (110). The thickness of the spacers (310a-f) can adjust the thickness and diameter of products processed by the pressing platen (110). For example, to increase uniformity among products pressed together in a press cycle, the spacers (310a-f) can have different thicknesses that correspond with the location of the spacer in the pattern of dough balls (104).


This study aims to determine how the social rehabilitation service program for children with the law. Using role theory by Biddle and Thomas, this research uses qualitative methods with data collection techniques through interviews, documentation, and observation. focuses on Expectations, Norms, Performance, Evaluation, and Sanctions. The result is that the Marsudi Putra Technical Implementation Unit Surabaya is used as a place of service for the protection of minors who commit criminal acts, with the existence of a rehabilitation center they will get protection rights, the rehabilitation process is given to all clients, sanctions from the Marsudi Putra Technical Implementation Unit can be given to staff who have problems with respect to existing guidelines. The rehabilitation program services provided by the Marsudi Putra Technical Implementation Unit are expected to provide lessons for minors who commit crimes so that they have a deterrent effect and do not make the same mistakes.


Abstract : This report summarizes the state-of-the-art in helicopter noise. It includes a bibliography of reports on all components of helicopter noise including main rotor, tail rotor, engine and gearbox. Literature on helicopter noise reduction and subjective evaluation of helicopter noise were also included. Capsule summaries of important reports are included which describe the purpose of the report, summarizes the important results, compares the report with others on the same subject, and provides a critical evaluation of the work presented. It is concluded that the available prediction methodology provides a means for estimating helicopter sources on a gross basis. However, the mechanisms of noise generation are still not fully understood, although the experimental and theoretical tools are now available to conduct the definitive experiments and establish the mathematical models needed for accurate definition of helicopter noise generation mechanisms. Spectrum analyses of helicopter noise show that main rotor, tail rotor, and engine sources contribute significantly to annoyance. In cases where these sources have been heavily suppressed, gearbox noise will also appear as a significant contributor to annoyance. Therefore, quieter helicopters must include suppression of all of these components. For certification, the liter


The effects of Re-B-C-N multi-elements penetrating on fatigue performance of 65Mn metal rubber made of thick wire were studied.The results show that static loss factor is the suitable fatigue criterion;the fatigue life of the metal rubber treated by Re-B-C-N multi-elements penetrating is increased by 28.6%.


Changbai mountain is one of biodiversitive centers in China. And live twenty five rare and endangered plants. The present situation and the reasons that the plants exhausted were analyzed and discussed.We have suggested some strategies in protection .


Turner syndrome (TS) is one of the most common genetic disorders associated with abnormalities of the chromosome X. Objective. The purpose of this study was to examine the prevalence TS, frequency of variants of the karyotype, the age of children at diagnosis, degree of stunting. Materials and methods. A retrospective analysis of registration cards 387 girls aged 11 months to 18.2 years from the database of patients TS for the period from 2004 to 2013. Results and discussion. Prevalence TS in Ukraine – 77.5 per 100 000 live births. The average age at diagnosis is TS 9,8±4,7 years [5.1;14.5]. At 1.6% of girls were diagnosed in the first year, 3.5% – at the age of 1-4 years, at 9.3% – at the age of 4-8 years, 18.8% in 8-12 years, in 66.8% – after 12 years. The most commonly diagnosed TS in puberty. Stunting TS girls with an average 3,2±1,08 SD [2.12; 4.28]. Among the options of chromosomal abnormalities in girls with TS in Ukraine most frequent monosomy (45, X) – 60.6%, at least – mosaicism (45 H / 46, XX) – 23.6%, structural abnormalities – 14.4% mosaicism with polysomes and X – 1.3%. Conclusions. Among prevalence TS among the population of Ukraine similarly prevalence in others countries. In Ukraine marked late diagnosis of Turner syndrome in children, with a maximum frequency of the initial registration of cases in puberty. The highest proportion of patients with Turner syndrome (58.3%) have a karyotype with monosomy of chromosome X. In Ukraine, Turner syndrome remains without due attention by pediatricians and other physicians, which does not allow a timely manner to establish the diagnosis and to provide appropriate medical, psychological and social assistance to the child and his family.


Transaction prices of financial assets are contaminated by market microstructure effects. This is particularly relevant when estimating volatility using high frequency data. In this article, we assess statistically the effect of microstructure noise on volatility estimators, and test the hypothesis that its variance is independent of the sampling frequency. We provide evidence based on the Dow Jones Industrial Average stocks. We find that noise has a statistically significant effect on volatility estimators at frequencies of 2–3 min or higher. The independently and identically distributed specification with constant variance seems to be a plausible model for microstructure noise, except for ultra high frequencies.


Water is the source of life and the fundamental element of ecology, and climate is inseparable from water. To evaluate the influence of water-adaptive space in a traditional Weizi (polder village) settlement on its microclimate, the authors analyzed the morphological characteristics of such a polder village and applied the ENVI-met model to simulate the impact of water bodies and village morphological elements on human thermal comfort. This paper demonstrates the positive impact of water bodies on improving the thermal environment of a village and regulating its microclimate by quantifying the impact of morphological elements of the settlement on microclimate. The results indicate that: 1) The simulation model fits the actual measurements well, and the simulation accurately reflects experimental results; 2) In summer, the cooling effect of water bodies is better in the afternoon than in the morning, especially from 12:00 to 15:00. The cooling effect is significantly correlated with the distance to water bodies, i.e., the closer, the better; 3) Building density and man-made underlying surface are negatively correlated with temperature, humidity, and Physiological Equivalent Temperature value, while greening rate and water body rate are positively correlated with microclimate. Overall, water bodies can improve outdoor comfort in summer and thus should be protected and developed in rural planning and design. Villages can be built around water bodies for a maximized cooling effect, and microclimate comfort can be effectively improved by increasing green plants near the village center, and reducing man-made underlying surface and building density. The results of this study will guide the improvement of the habitat environment in the process of rural revitalization, as well as the protection and re-development of traditional villages.


Thermal expansion microcapsules (TEMs) are widely used in various fields due to their unique structures. In recent years, TEMs have attracted much attention and have broad market application prospects. In this study, thermally expandable microcapsules with a core–shell structure were prepared by suspension polymerization using acrylonitrile (AN), methyl methacrylate (MMA), and methyl acrylate (MA) as monomers and low-boiling alkane as the core material. Through particle size analysis, morphology test, thermal analysis and other methods, the effects of core material types, single core material and mixed core material, dispersion system on the microcapsule structure, particle size distribution, and expansion properties were compared. Moreover, the core material with a content of 35% can make the expansion ratio of the microcapsules up to 4 times. The expansion performance of the microcapsules with a mixture of isopentane and isooctane (ratio 1:1) as the core material was increased by 27% compared with that of a single core material. In addition, comparing with colloidal SO2/PVP dispersant, the expansion ratio of the microcapsules with magnesium hydroxide as the dispersant was increased by 20%. Finally, the optimized method for preparing thermally expandable microcapsules was obtained.


The chemical composition of the methanolic extract of Ammi visnaga (Khella) seeds from the Sidi Slimane region is determined for the first time by Gas Chromatography coupled with Mass Spectrometry (GC/MS). Ten compounds representing 99.638% of the total extract were identified. Khellin (49.011%), Visnagin (26.537%) and Dimethylethylamine (15.108%) are the major components. Moreover, the inhibitory effect of the Methanolic extract of the seeds of Ammi visnaga on the corrosion of mild steel in a solution of 1M HCl is determined using weight loss measurements, the potentiodynamic technique as well as the technique of electrochemical impedance spectroscopy (EIS). It is found that the extract reduces the corrosion rate of the steel in the acid solution. Inhibition efficiency increases as the concentration of the extract increases. The tested compound has an inhibition efficiency of 84% for a concentration equal to 1.0 g/L. The polarization measurements indicate that the examined extract acts as a mixed inhibitor with predominant anodic efficacy. The data obtained from EIS studies are analyzed to model this process using appropriate equivalent circuit models. The adsorption of the extract on the surface of the mild steel obeys the Langmuir adsorption isotherm in acidic medium and the activation is determined and discussed.


In recent years there has been increasing concern about the growing volume of end-of-life electronic products. As the primary elements in most electronic products, Printed Circuit Board (PCB) is widely used and its recycling becomes a challenge not only to the industry, but also to the society. As an alternative environmentally benign method for PCB recycling, this dissertation adopts a novel processing method to separate the PCB scraps, which would increase the recycling rate and reduce the negative environment impact. Various solvent systems, i.e., carbon dioxide and water, are explored for delaminating PCB scraps at certain high temperature and pressure. For the purpose of finding an optimal condition for PCB delaminating, the experiment facilities were set up at the Advanced Manufacturing Lab (AML) in the Department of Industrial Engineering. Through series designed experiments, input parameters such as temperature, pressure and process time were recorded, and the output parameters, i.e., weight reduction, thickness expansion, impact energy variation were measured to evaluate the PCB delaminating results. Response Surface Method (RSM) was applied for selecting the input parameters. Multiple Objective Optimization method (MOO) was adopted to evaluate the overall delaminating effects. The utility theory was utilized to set up the utility function and figure out the optimal solution. Furthermore, the fundamental


Land is the basis of social, economic, and political development in most societies as it exhibits a close relationship to the style and quality of living of the society. There are many demands on land resources therefore, land has been frequently the basis of social upheaval and much effort was devoted to developing systems to administer land rights. Due to the influence of the different colonial powers, land administration systems in Africa vary from one country to another. To better understand the land administration systems in the region, the Eastern Africa land Administration Network (EALAN) attempts to carry a comparative analysis of land administration systems in the member countries. This paper illustrates the status of land Administration System in South Sudan by considering the institutional, legal, administrative and technical framework. The agencies responsible for the main elements of land administration and the challenges facing these agencies were also presented. The paper concluded by identifying areas of the needs for the development of land administration institutions in South Sudan. KEYWORDS: Land Administration Systems, Land registration, Land land use


Anakinra is an Interleukin - 1 receptor antagonist for the management of joint disease in Rheumatoid arthritis (RA). The structure, mechanism of action, indications, dosage and complications are described


In this paper, the theory of a new stochastic switching control strategy based on Linear Matrix Inequalities (LMIs) is applied to the bilateral teleoperation systems over networks with time delays and packet loss (Walker et al., 2008). The control algorithm in the theory part is here extended to a case with asymmetric communication channels. In the experiment, two identical 1-DOF (degree of freedom) manipulators are used as master and slave systems. The characteristics of the network with random time delays and packet loss are thoroughly incorporated in the design. Correspondingly, a stochastic switching control is proposed to ensure that the tracking error is bounded by the rate of change of the external forces acting on the system. Finally, experimental setup and results are extensively discussed.


Since 1986 Mali has had a program to vaccinate children and women of reproductive age against tetanus. Despite this effort routine data showed coverage for calendar year 2001 around 61% for children and 38% for women. The 2001 Demographic and Health Survey (DHS) showed similar coverage for women (32% had two or more doses of tetanus vaccine) but coverage for children was considerably lower: 34% were vaccinated by 12 months of age. Data also showed substantial differences in coverage based on locality of residence: women in the capital for example had 55% coverage versus 25% for women residing in rural areas. Risks presented by low coverage are amplified by the fact that 61% of births are at home. While such low coverage can be partially explained by .inadequate personnel who are obliged to work with dilapidated equipment in a poorly organized system it is also due to problems of geographic access cultural characteristics and lack of financing. Given these circumstances Mali was one of three countries in West Africa selected by UNICEF and WHO to participate in a maternal and neonatal tetanus elimination campaign. New technologies have resulted in the development of injection devices that can be used by non-health workers. Notable is the pre-filled auto-disable injection device called Uniject. Since tetanus vaccine is relatively heat stable tetanus filled Uniject devices could be used outside of the cold chain. It has been expected that tetanus toxoid filled Unijects TT-Uniject would enable innovative approaches to expand TT coverage by administration by lay providers with a more flexible cold chain storage and transport in areas of limited health facility infrastructure and/or staff shortages with a capacity to overcome acceptability concerns. The goal is to use it in areas and with populations less accessible and in parallel with usual methods of vaccination against tetanus (VAT) such as auto-disable syringes and multi-use vaccine vials. (excerpt)


Anglo-American law has historically prohibited fornication, and through the 1960s fornication remained illegal in all but ten states. Few questioned the validity of laws proscribing various forms of private, adult, consensual sexual behavior until the early 1970s. Aside from legislative repeal, substantive due process has been the primary weapon in the fight against state sex laws. Although the U.S. Supreme Court's substantive due process jurisprudence, particularly in the area of personal privacy, has brought the constitutionality of fornication statutes into question, it has not definitively resolved the matter. This Comment argues that laws prohibiting fornication do not violate substantive due process. It reasons that fornication laws need only withstand rational basis review because history does not support a right to fornicate, and the Supreme Court's privacy jurisprudence does not encompass such a right. This Comment contends, alternatively, that even if the Court were to find a fundamental right to engage in sex, fornication laws would withstand strict scrutiny. Finally, the Comment concludes that states should pass, but not necessarily enforce, fornication laws. Laws prohibiting fornication' remain on the books in at least thirteen states and the District of Columbia.2 Until the 1970s, few questioned the validity of laws prohibiting various forms of private, adult, consensual sexual behavior.3 Today, however, these laws, at the threshold of 1. Although statutory definitions vary slightly, fornication is the act of sexual intercourse between persons who are not married to each other. See Gerhard O.W. Mueller, Legal Regulation of Sexual Conduct 46 (1961). 2. D.C. Code Ann. § 22-1002 (1996); Ga. Code Ann. § 16-6-18 (1996); Idaho Code § 18-6603 (1997); 720 Ill. Comp. Stat. Ann. 5/11-8 (West 1993); Mass. Ann. Laws. ch. 272, § 18 (Law. Co-op. Supp. 1992); Minn. Stat. Ann. § 609.34 (West 1987); Miss. Code Ann. § 97-29-1 (1994); N.C. Gen. Stat. § 14-184 (1993); N.D. Cent. Code § 12.1-20.08 (1985); S.C. Code Ann. § 16-15-60 (Law Co-op. 1985); Utah Code Ann. § 76-7-104 (1995); Va. Code Ann. § 18.2-344 (Michie 1996); W. Va. Code § 61-8-3 (1997); Wis. Stat. Ann. § 944.15 (West 1996); see Richard A. Posner & Katharine B. Silbaugh, A Guide to America's Sex Laws 98-102 (1996) (listing enactment dates of state fornication statutes, ranging from as early as 1692 (Massachusetts) to as late as 1973 (North Dakota)). Additionally, at least four states that do not expressly prohibit fornication have outlawed cohabitation. See Ariz. Rev. Stat. Ann. § 13-1409 (West 1989); Fla. Stat. Ann. § 798.02 (West 1992); Mich. Comp. Laws Ann. § 750.335 (West 1991); N.M. Stat. Ann. § 30-10-2 (Michie 1994). It is also a federal offense to knowingly transport or persuade an individual to travel in interstate or foreign commerce with the intent that such individual enuage in criminal sexual activity. 18 U.S.C.A. §§ 2421-2422 (West Supp. 1998). See generally Posner & Silbaugh, supra (providing state-by-state review of fornication and cohabitation laws, including enactment dates). 3. Richard Green, Fornication: Common Law Legacy and American Sexual Privacy, 17 AngloAm. L. Rev. 226,228 (1988). Washington Law Review attempts to regulate sexual conduct,4 are the subject of much dispute. Courts nationwide are divided over whether fornication is a fundamental right, and whether the right to privacy protects private, consensual sex between unmarried heterosexual adults.' Some lower courts have upheld laws prohibiting fornication or deviant consensual sex between unmarried heterosexual adults as valid exercises of the police power; 6 others have struck down these statutes as violations of the right to privacy.7 The U.S. Supreme Court has found that the right to personal privacy includes an individual's liberty to make choices regarding contraception and abortion;8 nevertheless, it has upheld statutes prohibiting sodomy as applied to consenting homosexual adults.9 The Court has emphasized that its substantive due process opinions, particularly in the area of privacy, have not decided the constitutionality of statutes prohibiting fornication." This Comment argues that fornication statutes do not violate an individual's Fourteenth Amendment substantive due process rights. Part I briefly traces the history of fornication laws in the United States. Part II presents the framework for evaluating a substantive due process challenge. Part III summarizes the Supreme Court's privacy jurisprudence" and notes that neither the U.S. Supreme Court nor lower courts have resolved whether fornication proscriptions are constitutional. Part IV argues that no fundamental right to fornicate exists; thus, fornication statutes are subject to rational basis review. It notes that fornication statutes do not violate substantive due process because states have numerous rational bases for proscribing fornication. Part V contends that, even if the Court were to find that statutes prohibiting fornication warrant strict scrutiny, the statutes would withstand it. Part 4. Id. at 237. If fornication laws withstand substantive due process challenges, legislation related to less conventional private consensual sexual conduct, such as adultery and homosexuality, has a strong chance of being upheld. See id. at 238. 5. See, e.g., Schochet v. State, 580 A.2d 176, 181-82 (Md. 1990) (noting significant division among courts addressing constitutionality of punishing consensual sex between heterosexual adults). 6. See infra note 102. 7. See infra notes 99-100. 8. Carey v. Population Servs. Int'l, 431 U.S. 678, 685 (1977). 9. Bowers v. Hardwick, 478 U.S. 186, 189 (1986). 10. See, e.g., Carey, 431 U.S. at 688 n.5, 694 n.17. 11. The concept of constitutional privacy has embraced at least two different kinds of interests: the individual's interest in avoiding disclosure of personal matters, and the individual's interest in independence in making certain kinds of important decisions. Whalen v. Roe, 429 U.S. 589, 599-600 (1977). This Comment focuses on the latter. Vol. 73:767, 1998


There are numerous efforts to measure the degree of anonymity. Among which the entropy anonymity is a popular one. However in practice entropy anonymity is hardly used because one of its assumptions is difficult to meet. In this paper we propose a method to tackle this problem. Our method is based on Bayesian statistics and can be used to compare the entropy anonymity of different anonymous communication systems. We use this method to analyze Threshold Mix to show its effectiveness and usefulness.


Poverty blights the lives of children and young people. Research has consistently shown that the most economically disadvantaged pupils across the United Kingdom (UK) have the poorest educational outcomes and that poverty has a pernicious effect on children's well-being. However, far less is known about the ways that poverty is differentially experienced for children and young people in schools within the four jurisdictions of the UK. Are there historical, social and cultural factors that make poverty a postcode lottery in terms of quality of schooling in the different parts of the UK? Are successful local interventions context specific as the research evidence seems to suggest or can we learn from particular regions or cities? This introduction points out that anxieties about growing educational inequality in the UK have to be contextualised historically, geographically and in terms of the distinct political and socio-economic landscapes in England, Scotland, Wales and Northern Ireland.


In two studies, we compared whether making and viewing art improved affect and whether the affective benefits were due to participants' experience of enjoyment and flow. In Study 1, participants engaged in an art-making and art-viewing activity separated by one week. In Study 2, participants were randomly assigned to an art-making or art-viewing activity. In both studies, we induced a negative mood in participants by having them watch a sad film clip. We measured positive and negative affects before and after the mood induction and after the activity. In Study 2, participants rated levels of enjoyment and flow experienced during the activity. Both making and viewing art reduced negative affect equally. However, making art improved positive affect more than viewing art, and making art was associated with greater enjoyment than viewing art. Actively making art is a potentially more powerful way to improve affect than passively viewing art.


Deposition parameters determine the characteristics of semiconductor films in electrodeposition. Thus, it is essential to understand the effect of deposition parameters on the electrodeposited film for fabricating suitable semiconductor film fitting for various applications. In this work, the morphological and compositional properties of electrodeposited delafossite CuFeO2 film, according to the deposition parameters, were studied. The CuFeO2 film was fabricated by the galvanostatic electrodeposition and post-annealing process under inert gas flow. The type of solvent, electrolyte condition, applied current density and deposition time were controlled as the variable deposition parameters. As a result, the typical CuFeO2 film, without any impurities, was electrodeposited in the electrolyte-based DMSO solvent. Interestingly, the concentration of potassium perchlorate as a complexing agent caused morphological change in electrodeposited CuFeO2 film, as well as compositional transition. On the other hand, the applied current density and deposition time only influenced the morphology of electrodeposited CuFeO2 film. These observations would provide specific guidelines for the fabrication of electrodeposited CuFeO2 film with suitable composition and morphology for various applications.


To determine the soil water diffusivity, D(θ), by the horizontal infiltration method of R. R. Bruce and A. Klute (1956) the slope of the water distribution curve and the area under the curve must be evaluated. Experimental data often exhibit scatter, thus making the evaluation of the slope difficult. In this paper a rapid, simple method is described that introduces an empirical function that by linear least squares regression yields a curve that fits water distribution data for a wide range of soil textures. The function is differentiable, and its integral is easily calculated with a numerical technique available on programmable scientific calculators. The proposed method produces estimates of D(θ) that reach expected large values near water saturation. This result offers a clear advantage over other simple methods that assume an exponential relation between D and θ and thus describe D(θ) adequately only over the middle range of water contents.


A study was conducted at the LSU AgCenter Dean Lee Research Station in Alexandria, LA to evaluate insecticides for management of the SBL. Ten insecticide treatments, in addition to an untreated check, were assessed in a RCBD with 4 blocks and 1 replicate per block. Soybeans (HALO 4:94) were planted on 10 May on 38-inch centers (twin rows, 160,000 seeds/acre). Plots were 4 rows wide and 35 ft long. Insecticides were applied on 23 Aug, when SBL densities were approaching the LSU AgCenter recommended action threshold. All treatments were applied with the non-ionic surfactant Induce at 0.25% v/v. A CO2-pressurized backpack sprayer calibrated to deliver 10 gpa at 40 psi was used with a 2-row boom equipped with 4 TeeJet TX VS6 nozzles spaced at 19 inches. Treatment efficacy was evaluated on the 2 center rows of each plot by estimating percent defoliation and collecting insects from a 25-sweep sample with a 15-inch diameter sweep net. The two center rows of each plot were harvested for yield on 8 Oct. Defoliation data and SBL counts were compared using repeated measures ANOVA (PROC MIXED, SAS Institute). Yields were compared using a 1-way ANOVA (PROC MIXED, SAS Institute).


about four in 2 j p of the margin ; vasiforrn orifice about 25 / L broad, short and rounded, with the broad entire margined operculum practically filling the orifice$. I n the table by Mrs. Bemis (Proc. U. S. Nat. Mus., XXVII , p. 48j) , this runs to A. n i p n s , but differs in the regularly oval shape; the adult also is quite different. Adult about I 140 ,L long ; body above blackish, covered with white meal, the base and sides of abdomen white, the extreme base of wings yellow; beneath, the abdomen is light yellow, with the last two segments gray ; eyes black, com~~le te ly divided ; wings white, each with a small dusky spot in the apical field, alld also two very faint slightly iridescent clouds above the principal vein, one from the dusky spot toward the apex, the other apparently marking the place of the lost upper branch. Nearest, I think, to A. Dorseyi Iiirkaldy, but the dorsal area of the pupa is much more obtuse posteriorly rhan in that species, which occurs on R ~ I I N I I L Z L S in Califo~nia. The adult of A. Dorseyi is unknown.


Measurements are reported of the mobilities of helium ions in superfluid helium very close to the λ transition. The mobilities of both positive and negative ions appear to be singular in the sense of having infinite slope at the transition. The measurements are made by a new differential technique, based on the space-charge-limited method, which makes possible a sensitivity to changes in mobility of the order of parts in 104. This allows mobility measurements into the range |e|<10-4, where e=(T/Tλ)-1. Most of the reported measurements are taken along isotherms which cross the λ line at elevated pressures, although a series at saturated vapor pressure is also reported. Means of transforming the data between various thermodynamic paths are discussed. Uncertainty as to which thermodynamic path should be considered fundamental together with experimental problems in the technique at this stage in its development make quantitative assessment of the singularity difficult. However, if we assume a limiting form (μ-μλ)/μλ∼(-e)ρ′, where μ is the mobility and μλ its value at the transition, we find for the exponent ρ′=0.94±0.02.


CONTEXT: Changes in the healthcare system have resulted in shortened hospital stays, moving the focus of care from the hospital to the home. Patients are discharged post‐operatively with ongoing needs, and whether they receive nursing care post‐hospitalization can influence their recovery and survival. Little information is available about the factors that influence outcomes, including the survival of older cancer patients after cancer surgery.


It introduce economics of development,analyse power load and power require of 2002 years in yangquan city,and predict electricity requiremems from 2003 to 2005.


Thereafter, his 'intensely personal analysis of the play' is all too often a celebration of his own production and fellow performers in it. BerkoflPs accounts of his own dynamics of performance are more illuminating (also the occasions for some supremely self-conscious slabs of Berkoff Purple Verbals), and demonstrate his essentially heroic sense of drama, where energy can be equated with morality to an alarming degree ('This is grand and majestic . . . the lion's spirit roared out in hyperbole', 36). Elsewhere, Berkoff exhibits an almost endearing extent of selfcontradiction concerning Shakespearian text. He alternatively avows with a piety befitting Richard III, 'Let us obey Shakespeare and he will not lead us astray' (45), then lists copious cuts of ostensibly 'boring and unnecessary', slack or monotonous passages. Berkoff gives the reader a vivid and thorough account of a production: also irrelevant personal anecdote, theatrical gossip, laddish camaraderie, artistic sniping and political pontification which often remain unsubsumed into the drama he is otherwise describing. For example, his Falklands War analogies do not seem to be made theatrically overt or even particularly clear (as were Michael Bogdanov's in his 1983 production of Hamlet at Dublin's Abbey Theatre). This is a frustratingly spasmodic book, inaccountably dedicating a disproportionate amount of attention to the first three acts of the play. Intriguing metaphors like 'Shakespeare has a habit at the beginning of plays of being like a frantic knitter with four needles and many colours' are succeeded by populist deductions such as 'He digresses and needs trimming to reveal the core' (6), when it is BerkofTs writing that might profitably have been sent to to the barber's, or been sifted by an editor unintimidated by 'taurean bellows'. University College of Wales, Aberystwyth DAVID IAN RABEY


An interrogation scheme based on optical power monitoring was proposed and implemented to demonstrate a compact photonic temperature sensor, which incorporates a tunable silicon resonator with a heating electrode, a single-wavelength light source, and a photodetector. The temperature is basically determined by tracking the notch of the resonator, which is displaced by the thermal effects. By utilizing the proposed interrogation scheme, which did not require any complex spectral scanning, the ambient temperature was successfully estimated with a resolution of better than 0.1 °C over the range of 20 to 50 °C, and the electrical power consumption was ∼600 mW.


Market-oriented reforms affect RD input through the ownership structure and the market environment which includes level of marketization and demand for new products and funding environment.This article selects the panel data of China's high-tech industries during the period of 1995 to 2010,and using GMM method make an empirical analysis of the market-oriented reforms influence on the RD input.The result shows that improvement of level of marketization and growth of demand for new products have significant positive impact on RD input.Moreover the impact is more significantly after joining WTO.The improved funding environment promotes the growth of high-tech industry RD input.Too concentrated state-owned property is against the growth of RD capital investment,but it leads to too much RD manpower input.Market power has a non-linear inverted U-shaped relationship with RD capital investment and RD manpower input.The influence of firm size on RD capital investment is uncertain,but it has significant positive impact on the growth of RD manpower input.


This research aimed to study: 1) the suitable formula gluten free pasta supplemented with Cladophora spp., 2) the chemical and physical properties of pasta supplemented with Cladophora spp., and 3) the consumer acceptance. A mixture design experiment was conducted, and three factors were analyzed, 50-70% brown rice flour, 15-25%modified starch, and 10-20%Cladophora spp., the most suitable formula indicated 68%brown rice, 22%modified starch, 10%Cladophora spp.  The nutritional profile of this gluten-free pasta per 100 grams was 379.00 kilocalories of total energy, 7.09 grams of protein, 1.91 grams of dietary fiber, 0.11 milligrams of vitamin B, 0.11 milligrams of vitamin B2, 31.30 milligrams of calcium, and 3.84 milligrams of iron and antioxidant activity 48.50 mg eq Trolox. Most consumers' overall liking score was at a moderate level. The gluten-free pasta supplemented with Cladophora spp. will make better nutrition value.


Purpose – This paper aims to examine the development and effectiveness of quality assurance as a competitive tool for Singapore's private tertiary education in an increasingly competitive global market.Design/methodology/approach – A review of the growth of private education in Singapore is presented and issues related to quality and Singapore's quality assurance framework are discussed in this paper. The experience of "private schools", that is, private tertiary education providers, in relation to quality assurance is documented through two case studies of two typical private schools in Singapore.Findings – It was found that quality assurance of private tertiary education in Singapore is still narrowly focused on business and management processes. The government has not yet imposed any form of regulatory framework to ensure that academic standards are upheld. Rather, private schools are relying heavily on their own initiatives to safeguard teaching quality.Practical implications – This paper reveals the ...


Gastrin exists widely in gastrointestinal tract and pancreatic tissues,and plays an important role in the adjustment of physiological functions and pathogenic mechanism of some diseases.Recent studies show that gastrin might lead to the development of tumors,especially digestive tumors such as gastric cancer and colorectal cancer.It is promising to apply gastrin clinically to endocrine therapy for gastrin can speed up cell proliferation and inhibit apoptosis.


Syngnathia refers to congenital adhesion of maxilla and mandible by fibrous or bony tissues with only 55 reported cases in literature. Occurrence of syngnathia with non-formation of temporo-mandibular joint (TMJ) in the absence of any other syndrome or congenital abnormality is a very rare presentation. An 11-year-old boy was presented with complaints of extreme degree limitation of mouth opening with left sided bony syngnathia, non-formation of left TMJ, and zygomatic arch disruption. The rarity of condition with non-definitive management options suggests a poor prognosis.


Tasks that imply engagement of visual-spatial working memory (VSWM) are common in interaction with two-dimensional graphical user interfaces. In our paper, we consider two groups of factors as predictors of user performance in such tasks: (1) the metrics based on compression algorithms (RLE and Deflate) plus the Hick's law, which are known to be characteristic of visual complexity, and (2) metrics based on Gestalt groping principle of proximity, operationalized as von Neumann and Moore range 1 neighborhoods from the cellular automata theory. We involved 88 subjects who performed about 5000 VSWM-engaging tasks and 78 participants who assessed the complexity of the tasks' configurations. We found that the Gestalt-based predictors had a notable advantage over the visual complexity-based ones, as the memorized chunks best corresponded to von Neumann neighborhood groping. The latter was further used in the formulation of index of difficulty and throughput for VSWM-engaging tasks, which we proposed by analogy with the infamous Fitts' law. In our experimental study, throughput amounted to 3.75 bit/s, and we believe that it can be utilized for comparing and assessing UI designs.


Carbon nanotubes have many unique properties, including a tensile strength greater than that of steel and current-carrying capacity greater than any known metal or superconductor. Many applications have been identified, including field-emission displays and ultra-small transistors. At present, the main barrier to such applications is the ability to synthesize the nanotubes in a large scale with controlled properties'. The work reported here is an effort for growing carbon nanotubes on porous silicon with a designed pattern. Experimental procedures include (1) a liquid catalyst was prepared by mixing AlCl3.6H2O, SiCl4, FeCl3.6H2O, MoO2Cl2,P-123 chemical components; (2) a flat piece of polydimethylsiloxane (PDMS) elastomer stamp containing a designed pattern was etched in the oxygen plasma, followed by spin coating the catalyst on the patterned stamp;(3) the inked stamp was printed onto a porous silicon substrate. This substrate was then heated in air at 70°C for 10 minutes to stabilize the catalytic pattern on the surface of porous silicon.


Catalytic wet air oxidation(CWAO) is an effective water treatment technology for hazardous,toxic and high concentration organic wastewater.The impact of catalyst on CWAO as well as preparation,deactivation,reuse and regeneration of catalyst was reviewed,for the purpose to provide reference for researchers.


Introduction: Uterine arteriovenous malformation (AVM) is one of the rare conditions in gynecology. Conservative management such as uterine artery embolization can be tried to preserve the uterus. We have successfully treated a patient with recurrent uterine arteriovenous malformation with three times of uterine artery embolization. Case Report: A 35-year-old female presented with heavy vaginal bleeding. Uterine arteriovenous malformation was suspected by Doppler ultrasonography and it was confirmed with angiography. The first uterine artery embolization procedure was performed using polyvinyl alcohol but it recurred after one year and another recurrence after three years. Finally she was successfully treated with third uterine artery embolization. Otherwise, patient remained asymptomatic and keen for pregnancy. Conclusion: Uterine Artery embolization is a safe and effective treatment for recurrent uterine arteriovenous malformation. Hoo P.S.1, Norhaslinda A.R.2, Shah Reza J.N.3 Affiliations: 1Clinical Lecturer, Obstetrics and Gynaecology Department, School of Medical Science, Universiti Sains Malaysia; 2Clinical Specialist, Obstetrics and Gynaecology Department, School of Medical Science, Universiti Sains Malaysia; 3Senior Lecturer, Obstetrics and Gynaecology Department, School of Medical Science, Universiti Sains Malaysia. Corresponding Author: Pek Sung Hoo, Clinical lecturer, Obstetrics and Gynaecology Department, School of Medical Science, Universiti Sains Malaysia; Email: hoopeksung@ usm.my Received: 18 January 2017 Accepted: 04 May 2017 Published: 18 July 2017


AbstractAttention deficit hyperactivity disorder (ADHD) is a highly prevalent disorder that has an onset in early childhood, but persists frequently into adolescence and adulthood. Outcome studies suggest continued deleterious effects in adolescence and adulthood with continued academic impairment, and increased risk for the development of antisocial behaviors, substance abuse, and psychopathology. Recent findings indicate that ADHD is highly familial and that discrete subtypes may be identified based on patterns of comorbidity, particularly with conduct, mood, and anxiety disorders. These subtypes may have differing risk factors, clinical course, and pharmacological responses. Treatment needs to be multimodal and may include individual therapy, family counseling and parental guidance, cognitive and behavior therapy, remedial educational interventions, and pharmacotherapy. The mainstay of pharmacotherapy has been the stimulant medications, but alternative interventions including tricyclic antidepressants ...


The baryon-acoustic oscillation (BAO) feature in the Lyman-$\alpha$ forest is one of the key probes of the cosmic expansion rate at redshifts z~2.5, well before dark energy is believed to have become dynamically significant. A key advantage of the BAO as a standard ruler is that it is a sharp feature and hence is more robust against broadband systematic effects than other cosmological probes. However, if the Lyman-$\alpha$ forest transmission is sensitive to the initial streaming velocity of the baryons relative to the dark matter, then the BAO peak position can be shifted. Here we investigate this sensitivity using a suite of hydrodynamic simulations of small regions of the intergalactic medium with a range of box sizes and physics assumptions; each simulation starts from initial conditions at the kinematic decoupling era (z~1059), undergoes a discrete change from neutral gas to ionized gas thermal evolution at reionization (z~8), and is finally processed into a Lyman-$\alpha$ forest transmitted flux cube. Streaming velocities suppress small-scale structure, leading to less violent relaxation after reionization. The changes in the gas distribution and temperature-density relation at low redshift are more subtle, due to the convergent temperature evolution in the ionized phase. The change in the BAO scale is estimated to be of the order of 0.12% at z=2.5; some of the major uncertainties and avenues for future improvement are discussed. The predicted streaming velocity shift would be a subdominant but not negligible effect (of order $0.26\sigma$) for the upcoming DESI Lyman-$\alpha$ forest survey, and exceeds the cosmic variance floor. It is hoped that this study will motivate additional theoretical work on the magnitude of the BAO shift, both in the Lyman-$\alpha$ forest and in other tracers of large-scale structure.


This study aims to examine whether there is an influence between the understanding of regulations and the quality of tax service services on taxpayer compliance with taxation taxes as moderating. The data used in this study are primary data. This type of research is quantitative. The object of this research is taxpayers who are registered at the Tampan KPP Pratama Pekanbaru City. The sample collection method used random sampling method. Samples were taken as many as 100 MSME taxpayers. The data analysis test uses the Moderated Regression Analysis (MRA) method which is processed using SPSS 24. The results of this study indicate that the understanding of tax regulations and the quality of tax services have an effect on taxpayer compliance. Furthermore, the socialization of taxation is able to moderate the effect of understanding regulations and the quality of tax service services on taxpayer compliance.


The efficiency of converting sunlight to electricity via photovoltaic panels can be significantly improved by using sun tracking. Sun trackers are such devices for efficiency improvement. To solve the problem that the existing sun-tracking apparatus cannot work without electricity, this paper puts forward an automatic sun tracker driven by differential pressure controlled system. The system has two axes of motion, being respectively responsible for tracking the solar altitude angle and azimuth angle synchronously by exploiting one propellant gas with a low boiling point. The performance and working principle of the self-calibrating system will be introduced and tested. This paper also presents a self-locking device to assure the stability of the system and quantitatively researches the self-locking performance and unlocking conditions through an experiment. On the basis of experimental prototype, the feasibility of this type of sun tracker is verified.


A software quality evaluation systern is built and a quantificational method based on improved AHP is given.Through this method,the weight value of factors can be got directly and the consistent test is not required.


Aim of this study was to evaluate the microbiological quality of kebabs retailed in Palermo and Messina. Twenty raw and 22 cooked kebab samples were analysed to determine the aerobic mesophilic bacteria (AMB), Enterobac - teriaceae, Escherichia coli, sulphite reducing anaerobes, coagulase positive staphylococci, micrococci, Bacillus cereus and the presence of Salmonella spp. and Listeria monocytogenes. In raw kebabs, AMB ranged from 4.00 to 7.34 log cfu/g and Enterobacteriaceae from 1.00 to 7.59 log cfu/g. Escherichia coli and sulphite reducing anaerobe counts were from <1.00 to 6.18 and 4 log cfu/g, respectively. Coagulase positive staphylococci ranged from <1.00 to 3.48 log cfu/g and micrococci from <1.00 to 6.00 log cfu/g. Listeria spp. was found in three raw kebab samples. In cooked kebabs, the AMB values ranged from 1.78 to 6.30 log cfu/g, Enterobacteriaceae from 1.00 to 4.00 log cfu/g and micrococci from <1.00 to 5.30 log cfu/g. Three samples were positive for Escherichia coli (from 1 to 1.30 log cfu/g) and one for sulphite reducing anaerobes (2.00 log cfu/g). Coagulase positive staphylococci were found in two samples with loads of 2.30 and 2.78 cfu/g, respectively. Salmonella spp., Listeria monocytogenes and Bacillus cereus were not isolated in raw and cooked samples. The results of this study show that the microbiological quality of kebabs sold in Palermo and Messina is quite variable. The authors stress the importance of selection of raw material of high quality as well as the control of cooking and storage temperatures in order to minimise bacterial potential hazards.


Long Term Fertilizer experiment was initiated to monitor the continuous manuring and fertilization under intensive cropping changes in soil properties concerning to physical, chemical and biological characteristics and crop productivity. The experimental soil belongs to sandy clay loam soil (Vertic Ustropept) with ten different nutrient management practices followed and replicated thrice by the adoption of Randomised Block Design (RBD). Continuous use of inorganic fertilizer along with Farmyard manure (FYM) could increase the soil nutrients such as KMnO4 – Nitrogen, Olsen – Phosphorous and NNH4OAc – Potassium over five decades. The results revealed that the use of inorganic fertilizer conjoint with FYM at 10t ha-1significantly increased the kernel yield of maize by18.1% and 20.3% higher than 150% NPK and 100% NPK plots in sandy clay loam soil. The important indicator for soil fertility concern is Soil Organic Carbon (SOC) and the build-up of SOC was found in NPK+FYM at 10t ha-1 treatment recorded from 3.0 g kg-1 (1972) to 7.8 g kg-1 (2023). Soil fertility status of the experiment after 50 years had reported as medium in KMnO4- N, medium to high in Olsen - P, high in NNH4OAc - K and medium in SOC status in an Inceptisol. From the study, revealed that, the application of inorganic fertilizer along with FYM at 10 t ha-1 achieved a greater yield and better soil health in a sustainable manner.


Ph.D. Thesis "Successors of the Mrnjavcevic family and territories under
 their power 1370-1395" is a continuation of a centuries-old interest of
 national and foreign historians in the past of Serbia and southeastern Europe
 in the second half of 14th century. The weakening of the state of Nemanjic
 coincides with a new wave of Turkish presence on the continent, which
 permanently changed the past not only of the Balkans. Both King Vukasin and
 despot Jovan Ugljesa participated in the events and processes of global
 significance. Their rise has drawn special attention because it is usually
 associated with the end of Empire but also because the activity in the next
 period of King Marko and his three brothers (Andrejas, Ivanis and Dmitar) is
 at the center of the research. Besides, after the battle of Maritsa, mainly
 in the east of the Vardar River, more spacious state of brothers despot Jovan
 Dragas and gospodin (lord) Konstantin emerged. In order to explain this
 phenomenon, the biography of their parents, despot Dejan and Teodora, the
 paternal half-sister of Stefan Dusan, was extensively researched. General
 circumstances had contributed much more to their rises and falls than their
 personal characteristics. State polity, based on appanages, co-ruled
 principalities, "zemlja" - lands and "država" states, was especially
 distinguished. After the battle of Maritsa, Serbian independent land lords
 from the south established their dominions but over time they increasingly
 retreated before their north neighbours (knez Lazar, Vuk Brankovic, the
 Balsic family). In order to understand the multilayered relationships it was
 necessary to study complex and dynamic, political and diplomatic,
 administrative, economic, demographic, religious, cultural and spiritual and
 other processes within the two states and throughout divided Empire. New and
 interesting views occurred with the general conclusion that at the courts of
 king Marko and Dragas brothers, Serbian state policy was coordinated with
 increasingly modest possibilities. Also, the relationships with other
 substantial Balkan forces were researched with the conclusion that the
 Dejanovic family could have a significant influence on the situation in the
 Adriatic and Ionian hinterland, and Epirus and Thessaly. Over time, the Turks
 pressured more powerfully and comprehensively, so that the power of the two
 states weakened increasingly. There is not much source data on the Ottoman
 position towards the two courts; therefore a large section is devoted to the
 issues of Turkish vassalage in general and to the stages of their conquests.
 The key events which are singled out are the fall of Serres (1383) and
 Thessaloniki (1387) and in particular the battle of Kosovo. Deaths of King
 Marko and gospodin (lord) Constantine at the battle of Rovine 1395 were
 followed by probably silent vanishing of their states. Their contours are
 preserved in the early Ottoman administrative units. Besides, many lower
 institutions and numerous individuals adapted to the government…


Crosses were made between Ae.cylindrica Host Y127 and Ae.tauschii,Ae.cylindrica Host Y127 and T.durum Desf,Ae.cylindrica Host Y127 and wheat. The set rates of all distant hybridization descendants were extremely low and the dominant parts of seeds produced were abnormal,without embryo or without endosperm.The F_1 plants of wheat/Y127 gave many tillers, but the backcrossing or self-pollinating descendants produced few seeds.


The present invention relates to the gear portion and the driving motor having a drive shaft is formed, and gear-connected to the gear portion, cross the pair of spaced apart provided with the first and the second gear on the gear actuator for a dual-clutch, first and second which are connected to the gear rotates the first and the second guide cam and the first power transmission unit for transmitting the power of the driving motor according to the rotation direction of the first gear to the first cam or block, the second the performing a second power transmitting unit, the select operation of the first guide a linear motion by the rotation and odd-numbered gear positions of the cam for transmitting the power of the drive motor to the second guide cam or block, depending on the direction of rotation of the gear a linear motion by the fingers of the first shaft having a first finger, a rotation of the second cam, and includes a second finger syapeuteueul having a second finger to perform a select operation of the even-numbered gear positions. Accordingly, it is possible to perform the odd-numbered stage and the select operation of the even-that is separately provided as a driving part, the structure is simple, and because of the reduction in volume and weight of the parts can be effectively used as a space, the effect to improve the fuel consumption a.


Herpes simplex virus 1 (HSV-1) establishes latency within the sensory neurons of the trigeminal ganglia (TG). HSV-specific memory CD8 (cid:2) T cells play a critical role in preventing HSV-1 reactivation from TG and subsequent virus shedding in tears that trigger recurrent corneal herpetic disease. The CXC chemokine ligand 10 (CXCL10)/CXC chemokine receptor 3 (CXCR3) chemokine pathway promotes T cell immunity to many viral pathogens, but its importance in CD8 (cid:2) T cell immunity to recurrent herpes has been poorly elucidated. In this study, we determined how the CXCL10/CXCR3 pathway affects TG- and cornea-resident CD8 (cid:2) T cell responses to recurrent ocular herpesvirus infection and disease using a well-established murine model in which HSV-1 reactivation was induced from latently infected TG by UV-B light. Following UV-B-induced HSV-1 reactivation, a significant increase in both the number and function of HSV-specific CXCR3 (cid:2) CD8 (cid:2) T cells was detected in TG and corneas of protected C57BL/6 (B6) mice, but not in TG and corneas of nonprotected CXCL10 (cid:3) / (cid:3) or CXCR3 (cid:3) / (cid:3) deficient mice. This increase was associated with a significant reduction in both virus shedding and recurrent corneal herpetic disease. Fur-thermore, delivery of exogenous CXCL10 chemokine in TG of CXCL10 (cid:3) / (cid:3) mice, using the neurotropic adeno-associated virus type 8 (AAV8) vector, boosted the number and function of effector memory CD8 (cid:2) T cells (T EM ) and tissue-resident memory CD8 (cid:2) T cells (T RM ), but not of central memory CD8 (cid:2) T cells (T CM ), locally within TG, and improved protection against recurrent herpesvirus infection and disease in CXCL10 (cid:3) / (cid:3) deficient mice. These findings demonstrate that the CXCL10/CXCR3 pathway is critical in shaping (cid:2) T cell immunity, locally within latently infected tissues, which protects against recurrent herpesvirus infection and CXCL10 in trigeminal ganglia of latently infected CXCL10-deficient mice significantly restored the number of local antiviral CD8 (cid:2) T EM and CD8 (cid:2) T RM cells associated with protection against recurrent ocular herpes. Based on these findings, a novel "prime/ pull" therapeutic ocular herpes vaccine strategy is proposed and discussed. EM CD8 RM CD8 role hausted T cells expressing higher and more persistent levels of PD-1 than activated T cells do (68, 71, 72). Therefore, instead of relying only on the level of expression of PD-1, in the present study, we also determined coexpression of TIM-3 and 2B4 markers of exhaustion on CD8 (cid:2) T cells, as well as of two newly reported markers of exhaustion, TIGIT and VISTA (36–38, 73). PD-1, TIM-3, 2B4, TGIT, and VISTA were all coexpressed at various levels on CD8 (cid:2) T cells from TG of CXCL10 (cid:3) / (cid:3) deficient mice compared to CD8 (cid:2) T cells from TG of age- and sex-matched WT B6 mice. Mobilization of PD-1 (cid:2) CD8 (cid:2) T cells, TIM3 (cid:2) CD8 (cid:2) T cells, 2B4 (cid:2) CD8 (cid:2) T cells, TGIT (cid:2) CD8 (cid:2) T cells, and VISTA (cid:2) CD8 (cid:2) T cells in TG of CXCL10 (cid:3) / (cid:3) deficient mice point to exhausted (dysfunctional) CD8 (cid:2) T cells in TG. This was confirmed at the functional level by a decrease in the levels of CD107 a/b cytotoxic degranulation and by lower production of both IFN- (cid:2) and tumor necrosis factor alpha (TNF- (cid:3) ). These results are consistent with our recent finding of a significantly higher level of exhaustion of HSV-1 human epitope-specific CD8 (cid:2) T cells from TG of HLA Tg rabbits with higher virus reactivation compared to TG of HLA Tg rabbits with less virus reactivation (1, 7, 74). Because HSV-1 might coopt PD-1, TIM-3, 2B4, VISTA and/or TIGIT immune checkpoints as a strategy to


Based on the daily meteorological measurements of 106 meteorological stations in Northeast China from 1951 to 2007,the daily reference evapotranspiration(ET0) and yearly ET0 are estimated using the Penman-Monteith equation.Gridded annual and annual-average ET0 values for the region are produced using the inverse distance weighted interpolation method.The spatiotemporal variability of ET0 is analyzed using the methods of Mexican hat wavelet transform,Mann-Kendall test,the rotated empirical orthogonal function,and the inclination rate.The results show that:(1) a slightly increasing trend(3.89 mm/10a) is detected in the regional-average ET0 time series,and the regional ET0 minimum and maximum are found in 1953 and 1982,respectively;(2) the temporal variability of regional-average ET0 has a quasi-periodicity of 8-16 years experiencing four alternating stages(low-high-low-high),and in which an intensified ET0 oscillation of 8-10 years is observed;(3) the annual-average ET0 ranges from 600 mm to 1160 mm,and appears as obviously spatial difference exhibiting semi-ring-shaped isograms with a gradual ET0 increment from Northeast to Southwest;and(4) the annual-average ET0 shows a increase trend over 72.61% of the region domain based on the analysis of inclination rate,while the opposite result is obtained for the rest of the region;the maximum and minimum values of inclination rate are 30.6 mm/10a at Nenjiang station and-24.4 mm/10a at Yebaishou station,respectively.


e17536 Background: We aimed to assess the clinical features of disease progression (PD) based on Response Evaluation Criteria in Solid Tumors (RECIST) and CA-125 criteria, and analyse the impact on prognosis in ovarian cancer patients treated with poly (ADP-ribose) polymerase (PARP) inhibitors. Methods: All epithelial ovarian cancer patients included in this retrospective analysis were admitted to the Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University between January 2011 and July 2021. All enrolled patients were treated with PARP inhibitor monotherapy or combination therapy with antiangiogenic agents and regularly assessed with RECIST and CA-125 criteria until disease progression confirmed by RECIST criteria. Patients were divided to RECIST PD group and CA-125 PD group based on regular assessment: RECIST PD group comprised patients who were first confirmed with RECIST-assessed PD and did not achieve PD according to CA-125 criteria during the subsequent 28 days; CA-125 PD group comprised as follows: (i) patients who were first diagnosed with RECIST-assessed PD and defined as consistent if CA-125 PD occurred within the following 28 days; (ii) patients who had doubled CA-125 levels for the first time, confirmed after at least 1 week, and defined as consistent if subsequent RECIST progression occurred within 28 days of the initial doubling of CA-125; (iii) patients in whom the first occurrence of CA-125 was doubled and confirmed after at least 1 week, defined as priority PD of CA-125 provided there was no progression in RECIST assessment during the subsequent 28 days. Results: A total of 124 patients were included, with 64 (51.6%) in RECIST PD group and 60 (48.4%) in CA-125 PD group. Forty-three patients (34.7%) had disease progression consistent with RECIST and CA-125 criteria, 64 patients (51.6%) had priority PD with RECIST criteria, and 17 patients (13.7%) had priority PD with CA-125 criteria. The median interval between disease progression as determined by priority CA-125 criteria and subsequent RECIST criteria was 55 days (range 29–192 days). Patients in CA-125 PD group had a higher proportion of lymph node progression (40.0% vs. 17.2%, p = 0.005), multi-site disease progression (41.7% vs. 21.9%, p=0.018), and a worse prognosis with a median overall survival (OS) of 70.5 vs. 87.2 months (hazard ratio (HR)=2.01, p=0.015). In multivariate analysis, residual lesions after primary surgery (no vs. yes, HR=0.493, p=0.015), duration of PARP inhibitor treatment (≤ 6 vs. > 6 months, HR=2.262, p=0.006), priority criteria for PD (RECIST vs. CA-125, HR=0.441, p=0.006), and BRCA1/2 mutation status (wild-type vs. mutation, HR=2.150, p=0.028) were significantly associated with OS. Conclusions: Priority disease progression based on CA-125 criteria in ovarian cancer patients treated with PARP inhibitors might suggest a poor prognosis.


The attention around Ultra-High CPV is increasing year by year, because of the potential cost-cutting achievable by increasing the concentration ratio. In these systems, an adequate thermal management becomes particularly important: cooling systems are required to be compact, reliable and efficient. In this work, the geometry of a passive heat sink for a 4000x CPV application is optimized to reduce the volume and the costs, limiting the effects on the thermal performance. The same approach is used to model the behavior of a UHCPV heat sink in New Orleans, LA (USA): the hourly cell temperatures are presented in the paper.


Abstract : The Secretary of the Department of Homeland Security (DHS) and the Director of the Office of Personnel Management were authorized to prescribe joint regulations for a new human resources management system for DHS employees with the enactment of P.L. 107-296, the Homeland Security Act of 2002. The final regulations were published in the Federal Register on February 1, 2005. This report compares the final regulations with current law under Title 5 of the United States Code and relevant regulations under Title 5 of the Code of Federal Regulations. Specifically, Subparts A (General Provisions), B (Classification), C (Pay and Pay Administration), and D (Performance Management) of the final regulations are examined. (The regulations also affect labor-management relations (Subpart E) and adverse actions (Subpart F) and appeals (Subpart G), but these areas are outside the purview of this report.)


Comparison of 11 friction factor correlations was made with three sets of experimental data on triangular pitch tube banks to determine the best method for calculating the pressure drop across the convection section of a fired heater. The results indicate that a more thorough analysis comparing the various correlations with actual operating data is needed.


Prepectoral total breast reconstruction (PPTBR) has become a popular technique due to the many benefits observed in properly selected patients. Compared with the retropectoral implant position, PPTBR has the advantage of maintaining the pectoral major muscle in its anatomic original position, avoiding acute and chronic pain, maintaining better extremity strength and motion, and avoiding animation deformity and post-radiotherapy pectoral fibrosis. The basic principles of the technique can be used with a tissue expander or permanent implants. We present the preliminary report of 46 patients (51 breasts). In all, 20 out of the 46 patients had an association with radiotherapy; 18 of them received post-mastectomy radiotherapy and 2 received total breast irradiation on previous conservative treatment. The period of follow-up was 2–32 months, beginning in July 2019. The main surgical approach was using a lateral aspect of the inframammary fold incision. Depending on the new subdermal implant pocket width, in 20 patients, a synthetic mesh was placed. We only had two major complications: one who required reintervention due to radionecrosis and conversion to a dorsal flap plus a permanent implant, and the other who required a change into a retropectoral plane reconstruction due to wound dehiscence. No implant infection of grade 3–4 capsular contraction has been reported so far. The aesthetic result was excellent for most patients and the surgeon's opinion, according to the Harris scale.


For a number of well-documented watersheds and their adjacent coastal zones, a simplified, but generic approach was developed to explore current nutrient deliveries to their corresponding marine system, characterized by their flushing rate/residence time and morphology. An indicator of eutrophication was defined derived from both the C:N:P:Si stoichiometry of the riverine nutrient delivery and the physical features of the receiving marine bay (B_ICEP). Results show that the morphological and hydrological conditions characterizing coastal zones are the main determinants of the manifestation of eutrophication caused by an imbalance of nitrogen (and/or phosphorus) with respect to silica in the river nutrient loading. Action on the structure of the agro-food system of the upstream watershed, which determines the nitrogen losses to the hydrosystem, is identified as the most efficient control for attenuating coastal eutrophication. A comprehensive and generic concept of the systemic processes responsible for river and coastal water degradation can be achieved with a chain of nested models, describing the terrestrial agro-food system of the watershed, the river network, including the biogeochemical processes responsible for water quality, and the ecological functioning of the receiving marine area, in terms of carbon, nitrogen, phosphorus, and silica cycles. This leads to a land-to-sea continuum view, promoting interdisciplinarity and dialogue among the various scientific communities and their modeling approaches. This would also help the actors in multiple sectors (farming, fisheries, tourism, etc) and policy-makers make harmonized choices for a sustainable environment through an economically and socially viable way of life for all citizens.


A method for making, storing and using a surgical graft from human amniotic membrane; the resulting graft; and the storage solution. The amniotic membrane is obtained from human placenta, from which the chorion has been separated. Sheets of the amniotic membrane are cut to size and mounted on filter paper. The cells of the amniotic membrane are killed, preferably while being frozen and thawed in the storage solution. The storage solution comprises a culture medium and a hyperosmotic agent, wherein the hydration of the amniotic membrane is maintained. The membrane can be impregnated with therapeutic agents, prior to storage, for use in post surgical healing or other therapies.


The utility model discloses a fixing device for machining of workpieces. The fixing device for machining of workpieces comprises a base plate, a left supporting part, a right supporting part and interchange plates, wherein the left supporting part and the right supporting part are fixed at the lower sides of the two ends of the base plate respectively, the base plate is provided with at least one pair of through holes, a piston is embedded in each through hole, the lower end of each piston is connected with an air cylinder, a piston rod of each piston is exposed out of the corresponding piston and the surface of the base plate, a pressing plate is installed on each piston rod and is located between the upper end of the corresponding piston rod and the end surface of the corresponding piston, a left fixing seat and a right fixing seat are arranged between each pair of through holes, a notched groove is respectively formed in the inner side of each left fixing seat and in the inner side of each right fixing seat, and the two ends of each interchange plate are installed inside the notched groove of each left fixing seat and the notched groove of each right fixing seat respectively. The fixing device for machining of workpieces brings great convenience to machining of workpieces, improves machining efficiency, guarantees quality of products, and has the advantages of being rapid and accurate in positioning, high in machining efficiency and low in rejected rate.


This paper mainly discusses the use of tunnel technology in the transition from IPv4 to IPv6 and introduces the tunnel types and how to test the configuring and deleting of the tunnel.The reasonability is tested by detecting the technology.


School psychologists have a new and stronger position in Sweden's educational system than earlier. For example, as of July 2011, all Swedish students ages 6 through 18 have guaranteed access to school psychology services. The school psychologists' roles are to be active participants and coworkers in the student health service team, working to promote student health in the learning environment. The preparation of school psychologists, licensing, and specialists training in educational psychology are described. Sweden's school psychological services need further expansion at the undergraduate (first cycle) and master's (second cycle) level university courses as well as improved possibilities for professional development and training.


This letter describes a type of transistor that uses conducting fluidic source and drain electrodes of mercury which flow on top of a thin film of the organic semiconductor pentacene. Pumping the mercury through suitably designed microchannels changes the width of the transistor channel and, therefore, the electrical characteristics of the device. Measurements on transistors with a range of channel lengths reveal low contact resistances between mercury and pentacene. Data collected before, during, and after pumping the mercury through the microchannels demonstrate reversible and systematic tuning of the devices. This unusual type of organic transistor has the potential to be useful in plastic microfluidic devices that require active elements for pumps, sensors, or other components. It also represents a noninvasive way to build transistor test structures that incorporate certain classes of chemically and mechanically fragile organic semiconductors.


The hydrolytic decomposition of dichlorodifluoromethane (CFC-12) on modified zirconium oxide surfaces and on charcoal has been studied. The reaction was carried out under flow conditions at 450 °C. Complete CFC-12 conversion was obtained by employing a molar excess of water in the gas phase which depresses the formation of poisoning zirconium oxofluoride phases. These phases are responsible for the formation of unwanted monochlorodifluoromethane (CFC-13). The long-term stability of the catalysts was found to depend strongly on the CFC concentration in the gas phase. The lower the CFC concentration, the better the catalyst stability and catalytic activity. Pure charcoal can also be used as a catalyst for CFC hydrolysis. However, charcoal, owing to its reductive nature, may result in the formation of unwanted by-products and, thus, cannot be considered either as a serious catalyst nor as a suitable support.


In this work the air humidity (at 2 & 10 meters elevation above ground surface) and meteorological data were explored with the aim to study the temporal variation of air humidity and its association with weather and irrigation activities data parameters obtained from eleven (11) automated synoptic agro-meteorological TARBIL stations located in four different influential agricultural and administrative provinces of Turkey. In this preliminary version only the results for one of the stations are given. The data used in the work were obtained through the official web site of TARBIL - the Turkish Agricultural Monitoring and Information System for period of a year spanning between June 2014 and June 2015. Despite the fact that air humidity statistics at low heights as of 2m and 10m originate from both natural or manmade sources (like precipitation or irrigation) we tried to discover the trend variation of air humidity, based on multiple linear regression model ANOVA statistics and PCA analysis.


Deep geothermal energy systems employ electric submersible pumps (ESPs) in order to lift geothermal fluid from the production well to the surface. However, rough downhole conditions and high flow rates impose heavy strain on the components, leading to frequent failures of the pump system. As downhole sensor data is limited and often unrealible, a detailed and dynamical model system will serve as basis for deeper understanding and analysis of the overall system behavior. Furthermore, it allows to design model-based condition monitoring and fault detection systems, and to improve controls leading to a more robust and efficient operation. In this paper, a detailed state-space model of the complete ESP system is derived, covering the electrical, mechanical and hydraulic subsystems. Based on the derived model, the start-up phase of an exemplary yet realistic ESP system in the Megawatt range—located at a setting depth of 950 m and producing geothermal fluid of 140 ∘ C temperature at a rate of 0.145 m 3 s − 1 —is simulated in MATLAB/Simulink. The simulation results show that the system reaches a stable operating point with realistic values. Furthermore, the effect of self-excitation between the filter capacitor and the motor inductor can clearly be observed. A full set of parameters is provided, allowing for direct model implementation and reproduction of the presented results.


Results: The results show that the natural frequency of reinforced concrete columns increases quickly at an early stage of immersion, but there is little change when the columns are close to saturation; the difference between the natural frequencies before and after cyclic test grows as the moisture content rises. The damping ratio slightly decreases first and then increases with the increase of moisture content; the damping ratio after the cyclic test is larger than before the test due to the development of the micro-cracks.


Husband-wife agreed property system refers to such a system: The couple agrees on their property relation by covenant . It belongs to property conduct in effect according to the principles of property law, and is prior to legal property system. Legal restrictions on manner, time and scope of agreement are analyzed. How to undertake marital debts and the effect of agreement against strangers are argued.


A map of Antarctic subglacial-submarine relief has been compiled on the base of system-morphologic principle. Elements of subglacial-submarine surface represent the contents of the map. These elements include five types of structural lines (crests, talwegs, and others) and simple elementary surfaces, which are bound by structural lines and differ from each other by their place on the profile and relative steepness (14 types) and by their plan shape (3 types). Morphological and topological analysis of the elementary surfaces has helped working out the first geomorphologic regionalization of Antarctic according to system-morphologic principle. The same elements in the different regions differ in their morphometric features and in their role in the structure of subglacial-submarine surface.


When teaching dance history in the twenty-first century undergraduate classroom, how are dominant elisions within the Euro-American historical canon addressed? How might instructors integrate the choreographic voices, movement styles, and geographic regions that normative North American dance instruction—with its emphasis on ballet and modern dance, and (white) choreographers in the Global North—typically exclude? These questions frame Milestones in Dance History, edited by Dana Tai Soon Burgess, a textbook that insists on often-marginalized artistic lineages as essential to the dance historical field. Included within Routledge's Milestones series, "a range of accessible textbooks, breaking down need-toknow moments in the social, political, cultural, and artistic development of foundational subject areas" (p. i), Milestones in Dance History provides a necessary response to ongoing critiques of university-level dance instruction in the United States. Eurocentric thinking, in addition to Euro-American dance styles, are dominant in post-secondary curricula, which obscures the multiplicity of global dance histories and their continued resonances. The book attempts to resolve these erasures by inviting students to, first, encounter dance practices that are typically excluded from canonical syllabi, and, second, interpret their respective histories as connected to each other, rather than geographically and culturally discrete. A "milestone" references moments of importance, denoting significant change or development. On a literal level, it evokes markings on a road or map, often indicating where progress has been made. Milestones in Dance History engages this concept as a primary structuring principle: each of the book's ten chapters centers a milestone that "has shaped the different forms and genres of dance that we experience today" (p. xi). The chapters, which are "designed for weekly use" (p. i) in dance history courses, also cohere around the theme of "migration and political conflict" (p. x). Each author therefore prioritizes specific historical events, contextualizing their chosen


Objective: Masked (MUCH) and white coat uncontrolled hypertension (WUCH) are more and more frequently investigated for their long-term prognostic signifi cance Classifi cation is usually made by a single set of offi ce and out-of-offi ce blood pressure (BP) measurements during the treatment period. To evaluate the long-term reproducibility of MUCH and WUCH, an information crucial for determining the long-term prognostic impact of these conditions.


Electron-impact excitation cross sections for the 2p{sup 6}{yields}2p{sup 5}3l transitions in Fe{sup 16+} are calculated in a configuration-average distorted-wave approximation. Resonant-excitation contributions from the 2p{sup 5}3pnl{sup '}, 2p{sup 5}3dnl{sup '}, and 2p{sup 5}4lnl{sup '} series are included in the isolated resonance approximation. The accuracy of the distorted-wave calculations is determined by comparison with previous 139 level resolved (n{<=}5) fully relativistic R-matrix calculations. Excellent agreement is found between the configuration-average distorted-wave and R-matrix total rate coefficients for the strong 2p{sup 6}{yields}2p{sup 5}3p and 2p{sup 6}{yields}2p{sup 5}3d transitions, while differences found for the relatively weak 2p{sup 6}{yields}2p{sup 5}3s transition are mainly attributed to close-coupling effects.


Background: Stroke is a major cause of mortality worldwide and commonly occurs in elderly patients. After coronary heart disease (CHD) and cancer of all types, stroke is the third commonest cause of death worldwide. Primary prevention of stroke includes antiplatelet therapy with aspirin, statin therapy and blood pressure management. Effective prevention and treatment of infections should therefore be an important component in any strategy aiming to reduce the impact of stroke. The integration of the pharmacist role in management of stroke is very crucial and improves outcomes of the patients only by performing a critical medication utilization strategy. Objectives: The current retrospective study of six months duration was performed to assess the prescribing pattern and appropriateness of medication used in the stroke patients in an orthopedic multispecialty healthcare setting of India. Results: Ischemic stroke (65.56%) was more prevalent in our study, hyperlipidemia (47.05%) and hypertension (28.05%) were the most predominant diagnoses observed in majority of population. In our study male gender (66.67%) was more prone to stroke attacks, that too within age group of 61 – 70 years (22.22%), smoking (29%) was one of the cofound contributing risk factor, followed by family histories (80%). Anti-atherogenics and statins were majorly utilized in study population found rationale which is the value addition in stroke therapy. Conclusion: Our study showed a rationale utilization of drugs in stroke patients. Moreover, the study recommends regular and periodic drug utilization studies on medications in stroke patients for improving disease management strategy and quality of life in patients.


A successful transition from kindergarten to 1st grade requires a positive combination of multiple dimensions of child competence. Using latent class analysis, we simultaneously examined the academic skills, work attitude, and social/behavioral competence of a large sample of Dutch kindergarten children to identify profiles of kindergarten competence. We tested the predictive power of the profiles by means of multivariate multilevel analyses with language, arithmetic, and work attitude scores as outcome variables. Research Findings: Five profiles of children with distinctive combinations of skills were identified. The results showed that the profile solution forms a significant basis on which to predict later performance. In particular, children in the 2 profiles with the highest kindergarten competence levels perform significantly better in Grade 1 than children with less advantageous skill sets, an effect that tends to increase in magnitude at the end of Grade 2. Practice or Policy: We suggest a practical validation of these profiles to be used as tools for tailoring learning opportunities in kindergarten according to children's skill sets.


Two Islamic parchments dating back to the IXth century along with a third Jewish one whose age is unknown were investigated by means of a completely non-invasive multi-techniques analysis combining all of elemental XRF and structural Raman, ATR-FTIR and FOR spectroscopies. The materials initially used in the preparation of the writing supports were identified; while the Islamic parchments seem to be condensed tannins-pretreated, hydrolysable tannins and lead white have been highlighted in the Jewish one. Collagen gelatinization with molecular helix disorders phenomena have been highlighted in all parchments; degradation products, gypsum and calcium oxalates, have been identified in parchments supports and writing black inks. These latter have been characterized as iron gall types, while all coloring materials have been identified and characterized: Gold, natural minerals and insect extracts. In addition to constituting valuable scientific data prior to future restorations, the obtained results are highly helpful to: i) improving the available codicological data, ii) establishing the traceability of the investigated parchments and iii) enriching the knowledge of ancient writing supports and materials, and highlighting technologies and practices developed by middle ages craftsmen.


In this paper we revisit the deterministic version of the Sparse Fourier Transform problem, which asks to read only a few entries of x ∈ ℂⁿ and design a recovery algorithm such that the output of the algorithm approximates x, the Discrete Fourier Transform (DFT) of x. The randomized case has been well-understood, while the main work in the deterministic case is that of Merhi et al. (J Fourier Anal Appl 2018), which obtains O(k² log^(-1) k ⋅ log^5.5 n) samples and a similar runtime with the 𝓁₂/𝓁₁ guarantee. We focus on the stronger 𝓁_∞/𝓁₁ guarantee and the closely related problem of incoherent matrices. We list our contributions as follows.
1) We find a deterministic collection of O(k² log n) samples for the 𝓁_∞/𝓁₁ recovery in time O(nk log² n), and a deterministic collection of O(k² log² n) samples for the 𝓁_∞/𝓁₁ sparse recovery in time O(k² log³n).
2) We give new deterministic constructions of incoherent matrices that are row-sampled submatrices of the DFT matrix, via a derandomization of Bernstein's inequality and bounds on exponential sums considered in analytic number theory. Our first construction matches a previous randomized construction of Nelson, Nguyen and Woodruff (RANDOM'12), where there was no constraint on the form of the incoherent matrix.
Our algorithms are nearly sample-optimal, since a lower bound of Ω(k² + k log n) is known, even for the case where the sensing matrix can be arbitrarily designed. A similar lower bound of Ω(k² log n/ log k) is known for incoherent matrices.


Immunity to meningococcal disease is correlated with the presence of bactericidal antibody in serum. The role of the carrier state in stimulating production of bactericidal antibody was studied by obtaining samples of serum from military recruits before and after colonization with Neisseria meningitidis. The sera from 38 men, all of whom harbored meningococci that could not be grouped serologically, were assayed for bactericidal activity against their homologous carrier strains and selected pathogenic strains of groups A, B, C, and Y. Among these men, 38.9% developed antibody to their own strain; the proportion of those developing antibody to selected pathogenic strains of groups A, B, C, and Y was 20.6%, 52%, 47.8%, and 7.9%, respectively. These studies indicate that colonization of the nasopharynx of adults with nongroupable meningococci, which rarely cause disease, can be a potent stimulus to the production of bactericidal antibody, not only against the carrier's own nongroupable strain, but also against selected strains of known pathogenicity. These observations support the role of the nongroupable carrier state in developing and maintaining natural immunity to meningococcal disease.


Abstract : The volume is designed to aid in the transition of computer programs to the Computer Center of the Air Force Cambridge Research Laboratories. The programming package described herein, includes Hamiltonian Ray Tracing without magnetic field, HRT-2, and other programs used to display or generate electron density subroutines. (AUTHOR)


An important concern for current IaaS cloud providers is to be falsely accused by cloud users for the response delays of their applications running on the cloud. Since cloud computing brings an additional virtualization layer between guest-OS and hardware resources, the relationship between the performance of an application and its resource consumption becomes obscure. Only monitoring resource consumption (e.g., CPU, memory, disk I/O and so on) is often inadequate to detect the QoS degradation of a deployed application, not to mention resolving cloud users' QoS complaints. In this paper, we introduce a novel single-view performance visualization technique for a cloud platform to monitor the response delays of all the on-line applications running on it. Our technique sniffs network packets from a network switch in the platform and analyzes their flow to estimate the response time of each application. An important merit of this approach is the easy installation into a cloud platform. Concretely, our approach only requires changing the configuration of a network switch to enable port mirroring. To detect and visualize the response delay of each application in a single view, we convert the absolute response time of each application to a comparable value of delay degree ("delay ratio") which shows how serious the response delays compared to its baseline. The baseline is the service time of each application, which we estimate from the distribution of observed response times (service time + waiting time) by adopting an exponentially modified Gaussian (EMG) distribution fitting with an outlier elimination. We validate our approach through extensive experiments of a representative on-line application benchmark (RUBBoS). The results show high repeatability of the service time estimation (the standard deviation of 40 trials is 0.11). The results also show that our performance monitoring technique is able to accurately visualize response delays even when a training set of response times has a heavy-tailed distribution.


We have cloned by expression the cDNA encoding Trop‐2, a cell‐surface glycoprotein expressed by most human carcinomas. Formal proof of the identity of the clone is the hybridization to DNA and RNA from genomic TROP2 transfectants. TROP2 is a single‐copy gene in human cells, hybridizes to a single 1.8‐kb mRNA from expressing sources and encodes a 35,709 Da type‐1 transmembrane protein with a single transmembrane domain. TROP2 is essentially identical to GA733‐1. Thus, we have proven that GA733‐1, for which a protein product had not been identified, is a functional gene. TROP2 is also homologous to TROPI/KSA/GA733‐2, confirming the serological similarities between the 2 molecules. The homology between the Trop‐1 and Trop‐2 peptides is clustered in 2 extracytoplasmic domains and in the transmembrane/cytoplasmic region. Twelve cysteines and a potential cytoplasmic tyrosine phosphorylation site are also conserved. Trop‐1 and Trop‐2 are homologous to serum IGF‐11‐binding proteins and appear as signal transducers. Thus, they likely represent novel cell‐surface receptors and may play a role in regulating the growth of carcinoma cells. On the other hand, we have found no evidence for a role of Trop‐2 and Trop‐1 as homophilic adhesion molecules. © 1995 Wiley‐Liss, Inc.


A method for grinding coffee beans in a coffee machine is described. The method the steps of: arranging a first grinding wheel (55) and a second grinding wheel (57)in a seat (53), the grinding wheels forming a grinding volume there between and rotating one with respect to the other; introducing coffee beans into said grinding volume and grinding the coffee beans by rotating the grinding wheels one with respect to the other. Rotation of the grinding wheels is continued after grinding of the coffee beans, thus removing ground coffee therefrom by centrifugal force.