The objective of the present invention is to select a solution according to the air conditioning control objective among multiple Pareto solutions indicating the amount of operation to control the air conditioning environment. An index calculation unit (15C) calculates indexes of one or multiple kinds for each Pareto solution to evaluate the similarity of air conditioning control based on the operation amount and/or condition distribution of the corresponding Pareto solution. A similarity calculation unit (15D) calculates the similarity of each Pareto solution to a reference Pareto solution based on the indexes of the corresponding Pareto solution and the indexes of the reference Pareto solution selected as a reference among Pareto solutions. A Pareto solution display unit (15E), based on the evaluation value of each Pareto solution obtained using an objective function, displays the symbol of each Pareto solution with a plot at a position of certain coordinates corresponding to the evaluation value on a display screen and displays the symbol of each Pareto solution with an identifier according to the similarity to the reference Pareto solution. [Reference numerals] (10) Air conditioning solution display device; (11) Communication I/F unit; (12) Operation input unit; (13) Screen display unit; (14) Memory unit; (14P) Program; (15) Calculation processing unit; (15A) Distribution system flow analysis unit; (15B) Pareto solution designation unit; (15C) Index calculation unit; (15D) Similarity calculation unit; (15E) Pareto solution display unit; (20) Air conditioning system; (21) Air conditioning processing device; (22) Air conditioning device; (30) Air conditioning control device; (50) Air conditioning space


In this memoir, we shall consider weighted convolution algebras on discrete groups and semigroups, concentrating on the group (Q, +) of rational numbers, the semigroup (Q+•, +) of strictly positive rational numbers, and analogous semigroups in the real line R. In particular, we shall discuss when these algebras are Arens regular, when they are strongly Arens irregular, and when they are neither, giving a variety of examples. We introduce the notion of 'weakly diagonally bounded' weights, weakening the known concept of 'diagonally bounded' weights, and thus obtaining more examples. We shall also construct an example of a weighted convolution algebra on N that is neither Arens regular nor strongly Arens irregular, and an example of a weight ω on Q+• such that lim infs→0+ ω(s) = 0. Acknowledgements. This memoir was commenced whilst the second author held a Commonwealth Fellowship and a London Mathematical Society Scheme 2 Grant to visit the University of Leeds in 2006; we are grateful for this support. The second author is also grateful to UGCSAP-DRS grant No F.510/5/DRS/2004(SAP-I) provided to the Department of Mathematics, Sardar Patel University. 2000 Mathematics Subject Classification: Primary 46H20; Secondary 43A20.


Nowadays, the Family Health as a strategy has been takes as priority in many Brazilian municipalities. This article brings a reflection on family and mental illness issue in the Family Health Program (FHP), highlighting the team's possibilities of care to families with persons suffering from mental disorder. We intent to emphasize in which aspects the FHP are ideal to include the mentally ill patient into the community.


In many applications, users face the need to integrate multiple information sources to solve their tasks. While most information sources can be seen as stable, as they contain factual, objective knowledge (which is the case for most relational databases), there can be personalized contextual knowledge which enriches the available factual data and contributes to their interpretation, in the context of the knowledge of the user who queries the system. In this paper, we present CrowdSourced Semantic Enrichment (CroSSE), a social knowledge platform supporting semantic enrichment and integrated services (such as content personalization, preview, and social recommendations) within the context of scientific investigations. Semantic enrichment is especially useful in applications where data (schema and facts) evolve faster than the database itself and, while essential to the operation of the enterprise, the database lacks the flexibility to (a) prevent going stale or (b) capture user-provided and/or crowdsourced data and knowledge for more effective decision support. More specifically, in this paper, we focus on the SESQL language and the supporting system architecture, which enables users to (a) enrich a databank with semantic tagging information and (b) leverage contextualised queries to the databank for enabling contextualised data analysis.


Other articles, by such leading scholars as Andrew Skinner, Donald Livingston, and Jeffrey Smitten, show how the American experience informed or illuminated the thought of luminaries like Adam Smith, David Hume, and William Robertson. David Daiches provides a characteristically elegant discussion of the ways in which the rebels of the American Revolution borrowed the literary style of that more conservative and politically lame Scotsman, Hugh Blair. Equally elegant and informative are the contribution and introduction by Richard Sher. A book of essays o consistently well written and edited is a rare and precious find. The only weakness of this volume, perhaps, is that the final essays on music, medicine, and architecture in Philadelphia tend to be pedestrian. While they doubtless contain new and valuable information, they fall flat in comparison with the literary and analytical feast that characterizes the rest of the book.


The angular dependence of the cumulative particles production off nuclei near the kinematical boundary for multistep process is defined by characteristic polynomials in angular variables, describing spatial momenta of the particles in intermediate states. Physical argumentation, exploring the small phase space method, leads to the appearance of equations for the polynomials in cos(θ/N), where θ is the polar angle defining the momentum of final (cumulative) particle, the integer N being the number of interactions. The recurrent relations between polynomials with different N and their factorization properties are derived, the connection of these polynomials with known in mathematics Chebyshev polynomials of 2-d kind is established. As a result, differential cross section of the cumulative particle production has characteristic behaviour dσ∼1/π−θ near the strictly backward direction (θ ∼ π, the backward focusing effect). Such behaviour takes place for any multiplicity of the interaction, beginning with n = 3, elastic or inelastic (with resonance excitations in intermediate states) and can be called the nuclear glory phenomenon.


By definition, Aeromonas salmonicida is found in fish but never in surface water. However, this does not explain the reason for explosive out-breaks of furunculosis among populations of salmonid fish which have never been exposed to the disease. Evidence is presented, from laboratory-based experiments, which show that A. salmonicida survives in freshwater, beyond the period necessary for plate counts to reach zero. These cells may subsequently be re-activated by the addition of nutrient. It may be assumed, therefore, that A. salmonicida survives outside of fish, by entering a dormant phase.


Abstract Oil and gas discoveries spurred expectations of economic growth and employment in Ghana. The demand for labour is however limited within offshore petroleum extraction. Employment generation therefore depends on the development of an onshore oil and gas service sector. This study examines the strategies adopted by local entrepreneurs in the 'oil city' of Takoradi, focusing on the gendered nature of their activities, skills, networks and capital sources. I argue that the petroleum industry's male dominance and international standards requirements, coupled with gender constraints regarding work and access to relevant resources, limit female entrepreneurs' creation of employment in this emerging sector.


We cannot reflect on our own cultural context without knowing another one. We need to stand aside from our own context in order to un- derstand the difference. Huertopoema condenses this vision of poetic identi- ty, of the space of the crop and the poem, in search of balance in the use of topos, such as the garden and as a form of artistic life; farm labour; sowing and harvesting are synonyms of poiesis . Its fundamental principle is based on an elementary spatial order and rational arrangements, as well as a com- parative grammar that encrypts its interpretation and its knowledge not only in aesthetics, but through intuition. Like a sculpture, like a musical score, like a painting, a poem made into a garden; just as words are laid out on the page, the furniture in the space of the room, a huertopoema functions as a complete work: earth, water, air, day, night, fruit, vegetables, animals and people live together, coexist, make the huertopoema . There is a direct refer- ence to "concrete poetry", to concrete music; to take a case in point, the


A Cluster Approach to Destination Development - Network Structures and Contextual Factors in the Evolution of the Mountain Resort of Are, Sweden


Previous studies have indicated that cortisol hypersecretion and abnormal cortisol responses to dexamethasone (DEX) could be both associated with low levels of plasma melatonin (MT). In this study, the possible relationship between urinary MT excretion (8 PM-8 AM) and the CRF-ACTH-Cortisol axis was investigated. 39 children and adolescents whose weight for age was above the 97th percentile received 2 mg of DEX at 8 PM. Plasma cortisol levels were determined at 8 AM and 5 PM before, and at 8 AM after DEX administration. 15 patients with a normal cortisol cycle (12.1±1.4 and 3.1±0.5 μg/100ml), and levels below 1.0 after DEX, showed a highly significant increase in MT excretion during the night following DEX administration (63.8±5.6 ng/12h vs 33.1±3.0 for the control night, p<.001). In a second group of 14 patients with mean cortisol levels similar at 8 AM and 5 PM (10.7±1.3 and 9.3±1.5), but with a normal cortisol decrease after DEX, nocturnal MT excretion increased from 21.5±2.2 to 34.7±5.6 (p<0.02). A third group of 10 patients with both poor cortisol cycles (16.1±2.5 and 10.8±2.4) and abnormal cortisol suppression after DEX (7.6±2.1), showed no increase in MT excretion (24.2±2.7 and 24.9±3.7). The reciprocal changes in plasma cortisol and MT excretion in obese subjects suggest a relationship between the CRF-ACTH adrenal axis and the pineal gland.


Shows a view of a coastal settlement spread along the water's edge, backed by bush-clad hills, and seen from the water. Thames, originally named Shortland, was established in 1867 as a goldmining town, but had grown to the size shown here by 1870. The buildings depicted are likely to include miners' houses, hotels and stamper batteries
Quantity: 1 watercolour(s).
Physical Description: Watercolour 165 x 770 mm (trimmed)


This article presents a dual-polarized corrugated horn antenna incorporated a turnstile orthomode transducer (OMT) covering the full Ka-band (26.5–40 GHz). A three-stepped cylindrical tuning stub scattering element is designed in the turnstile junction to combine/split the two linearly polarized waves with high isolation. The proposed turnstile OMT shows a good simulated return loss better than 20 dB and a high isolation higher than 57 dB within the whole Ka-band. Then, a corrugated horn antenna with five-stage choke rings is designed. Finally, the proposed horn antenna incorporated in the turnstile OMT is fabricated and measured. The measured impedance bandwidth for |S11/22|≤ −15 dB is 50.7% from 25 to 42 GHz. The measured peak gain is 11.9 dBi. The proposed antenna system is a promising candidate for the 5G millimeter-wave applications.


Presentation of Case A 15-year-old right-handed girl was admitted to the hospital because of hemiparesis, slurred speech, and urinary retention. The patient had been in excellent health until two a...


Latterly, the formation enthalpies were determined for many carbocations by means of thermochemical methods. Therefore a thermodynamical view is possible for the propagation reactions of the cationic polymerization to a larger extent.

In letzter Zeit wurden fur viele Carbokationen die Bildungsenthalpien thermochemisch bestimmt. Damit wird in erweitertem Umfang die thermodynamische Betractung der Wachstumsreaktionen der kationischen Polymerisation moglich.


An immunomodulatory polynucleotide having less than 50 bases or base pa- res and comprising a sequence selected from SEQ ID NO: 1, SEQ ID NO: 19 and SEQ ID NO: 132.


Breeding red-throated divers Gavia stellata were studied in Shetland during 1981-1983. The overall probabilities of nest success were 0.35 in 1981 and 0.25 in 1982, as calculated by the Mayfield method. Productivity was shown to be at least 0.51 chicks fledged per breeding pair in 1981 (n = 100) and 0.36 in 1982 (n = 91), and a review of all field studies for Shetland gave a mean value of 0.45 per year (n = 1104) with no detectable trends in productivity since 1918; this was considered probably sufficient to maintain a stable population. Nests at lochs smaller than one hectare experienced the greatest hatching success. The majority of known breeding lochs wore used in three consecutive years, with a significantly greater re-use of lochs which had previously supported successful pairs. Breeding success declined with season in 1981 and 1982 largely due to reduced hatching success of late nesters, and a slight seasonal decline in egg volume was found in 1983.


Some very persistent problems in our attempts to reconcile the theory of general relativity to quantum mechanics, lead one to suspect that the fundamental principles of both of these theories will have to be reconsidered.


The design, fabrication, and demonstration of an electrorheological valve that operates at reduced electric field are presented. An electrorheological liquid crystal flows between upper and lower electrodes. Applying an electric field aligns the liquid crystal with the field, increasing its apparent viscosity. Valves with conventional flat electrodes and patterned valves with 200 µ m high protrusions on the electrodes are compared. The increase in apparent viscosity in patterned valves is about 2.5X greater than in valves with flat electrodes under the same average field. Patterned-electrode valves can potentially control hydraulic actuation of mechanically biomimetic soft robotic organs.


Women with a history of gestational diabetes (GDM) are at high risk for developing type 2 diabetes, which may be further increased with weight gain after pregnancy. Our objective was to determine associations of long-term weight changes after a GDM pregnancy and type 2 diabetes risk. We used data on a cohort of 139 women with a GDM pregnancy identified though the Kaiser Permanente Northern California (KPNC) GDM registry (1986-2009) who completed a follow-up study visit an average of 16 years later (2011-2013). Type 2 diabetes was identified through the KPNC diabetes registry, self-report during follow-up visit recruitment, or at least one abnormal value on a 75-gram, 2-hour oral glucose tolerance test (2015 ADA criteria) conducted at the follow-up visit. Clinically measured weights extracted from the electronic health record were used to calculate average BMI change per year between delivery and either type 2 diabetes identification date or follow-up visit date. We used modified Poisson regression to estimate relative risks of type 2 diabetes associated with BMI change categories. Twenty-six percent of women lost weight [mean -0.3 BMI units/year, equivalent to -0.8 kg/year for a woman of the average height in our cohort (1.6 m)], 24% maintained their weight ( Disclosure S.E. Badon: None. F. Xu: None. C. Quesenberry: None. A. Ferrara: None. M.M. Hedderson: None. Funding National Institutes of Health (R01HD065904)


For more than five years, the CLIC Test Facility (CTF) has used photo cathodes (illuminated by laser) as intense sources of electrons. These cathodes are mounted in an RF gun at 3 GHz and subjected to high electric fields, greater than 100 MV/m, in order to produce a beam charge of more than 10 nC in less than 10 ps. Traditional photo cathodes developed for photo multipliers have been shown to be unsuitable for our application. After having tested several types of photo cathode, metallic, semi-conductor or impregnated, we have selected two, compatible with the specifications of the photo injectors and, at the same time, with the technical performance of our laser installations. One of them, in caesium telluride, allows the production of high charges, but must be transferred under vacuum from the production laboratory to the RF gun. The other, in caesium iodide, covered with a fine layer of germanium, produces smaller charges, up to several nC but, in contrast, it can be exposed to the air for short periods. After having recalled the main characteristics of the photo cathodes that we have tested, including the first test of a GaAs photo cathode in an RF gun, this note describes in more detail the two cathodes which were selected and their use in an RF gun.


In this paper we outline a Knowledge Transfer Partnership (KTP) R & D Project involving the University of Leeds and Hydro-Logic Ltd aimed at combining radar and raingauge data in real-time within urban areas. The project also involves three Water Companies, Yorkshire Water, Northumbria Water and Scottish Water, who will purchase three dense raingauge networks for three urban areas Bridlington, Filey and Scarborough, Newcastle and Glasgow (Figure 1). The motivation for the Water Companies is linked to their Asset Management Programmes (AMP) 5 concerned with developing storm intensity alarms before sewer flooding occurs, and post-event analysis through improved storm frequency statistics. For each incident of sewer flooding the UK Environment Agency may impose a fine of around £20k upon a Water Company. At present in the UK urban areas suffer from a lack of dense raingauge networks. Those tipping bucket raingauge networks that are available are costly to maintain, and often have uncertain calibrations. Also radar data in cities is sometimes of poor quality, particularly in short-period convective storms, Hence, the raingauge and radar data will be merged in real-time, with the raw data and merged product being stored in a Web-based archive. Prototype facilities will be provided for the Water Companies to access the quality controlled radar and raingauge data.


Taking Hebei poplar as test material,the control effect of 20%triadimefon EC,12.5% diniconazole WP and 50%thiophanate-methyl WP on Uromyces transversalis(Theum) Wint.were studied.The results showed that 20% triadimefon EC 800 1 200times and 12.5%diniconazole WP 1 500~3 000times would both get a better effect,with the control effect more than 92.3%,and the control efficiency were significantly better than 50%thiophanate WP 600times.


The last years it is a good time in heart failure for innovative therapy. The results of new trials which were published after the last 2016 guidelines for heart failure need the systematic approach and present the practical guide based on EBM. For that reason in the last year 2019 the experts of Heart Failure Association (HFA) European Society of Cardiology published the consensus. The present article summarized the main issues regarding heart failure with reduced ejcetion fraction together with comennt based on the HFA expert consensus.


In this paper, we compare, first, the impact of a windfall and a boom sectors on the economy of an oil exporting country and their welfare implications ; in a second step, we analyze how monetary policy should be conducted to insulate the economy from the main impact of these shocks, namely the Dutch Disease. To do so, we built a Multisector DSGE model with nominal and real rigidities. The main finding is that Dutch disease effect arise after spending and resource movement effects in the following cases : i) flexible prices and wages both in the case of a windfall and in the case of a boom ; ii) flexible wage and sticky price only in the case of a fixed exchange rate. In other cases, Dutch disease effect can be avoided if : prices are sticky and wages are flexible when the exchange rate is flexible ; iii) prices and wages are sticky whatever the objective of the central bank is in both cases : windfall and boom. We also compare the source of fluctuation that leads to Dutch disease effect and we conclude that the windfall leads to a strong e¤ect in terms of de-industrialization compared to a boom. The choice of flexible exchange rate regime also helps to improve welfare.


Binary Fe-28 at.% Al alloys (Fe[sub 3]Al-type) transform from B2[yields]DO[sub 3] ordered phases at 550[degrees]C upon cooling. More complex Fe-28Al alloys can have B2[leftrightarrow]DO[sub 3] transition temperatures that range from 530 to 670[degrees]C. Kinetics of the B2[yields]DO[sub 3] ordered phase transition also appear to be affected by alloy composition and by matrix dislocation microstructure. The binary and Nb-containing ternary alloys have rapid B2[yields]DO[sub 3] transition kinetics during cooling. However, the ternary or more complex alloys that contain Cr have relatively slower phase transition kinetics during similar cooling. Deformation of a complex Fe-28Al-5Cr alloy in the B2 phase regime creates a very high matrix dislocation concentration, which coincides with complete suppression of the B2[yields]D0[sub 3] phase transition during cooling.


Abstract: External information is commonly collected for, and provided to, evaluation stakeholders without giving due consideration to their precise needs. As a result, evaluation resources are often inefficiently consumed and the impact of the evaluation process is diminished. The External Information Search and Formatting (EISF) process is a new approach that seeks to avoid such an outcome. This tool requires that the information searcher collaboratively work with his or her stakeholders to ensure that their informational needs are well met and the information is presented in a manner that is useful to them.


Zionist colonization, even the most restricted, must either be terminated or carried out in defiance of the will of the native population. This colonization can, therefore, continue and develop only under the protection of a force independent of the local population - an iron wall which the native population cannot break through. This is, in toto, our policy towards the Arabs. To formulate it any other way would only be hypocrisy.--Vladomir Jabotinsky, The Iron Wall (1923)In 2002, the Israeli government began construction of an eight-meter-high concrete barrier which would come to surround and cut through much of the West Bank of Palestine. Though concrete was selected in favor of iron, nearly eighty years after writing, Vladimir Jabotinsky's crude blueprint for the colonization of Palestine was realized. Jabotinsky's ideas formed the basis of Revisionist Zionism, a brand of European Jewish nationalism that was most uncompromising in its views of how to treat with indigenous Palestinians, as well as how to confront the British, who controlled Palestine at the time of Jabotinsky's writing.1 Jabotinsky and his followers believed that nothing short of literal separation between the colonists and indigenous Palestinians would be safe for Zionist colonists, and though Israeli strategies of occupation often created de facto separation of Palestinians and Israelis, the construction of the wall in 2002 was the first time the Israeli government enacted steps to literally separate Palestinians and Israelis en masse.Through the following case study of the separation wall in Palestine, I argue that spaces in Palestine that attract international actors can be used by Palestinian actors to access transnational spaces and networks. Following Saskia Sassen's conceptualization of the global city, spaces become transnational when they are the hub of various transnational networks, and those networks are transnational because they move goods or ideas that cannot be quantified or mapped onto a foreign/domestic dichotomy.2 This essay analyzes how graffiti is used as a tool by Palestinians and others to communicate messages from within Palestine to transnational audiences.Palestine has been the hub of many transnational networks, some decades old and others centuries old. Historically, these networks included sites of commerce and pilgrimage, as well as those networks that gave rise to Zionist immigration in the late nineteenth century and, later, British and U.S. support for the Zionist project in Palestine. Variations of many of those networks grow and adapt in contemporary Palestine, and have grown to include those who support and oppose the occupation of Palestine. This paper focuses on how graffiti in Palestine attempts to link up with networks of Christian religious tourists and anti-occupation activists.Through analyzing the content and location of graffiti on the separation wall near Bethlehem and Jerusalem, I argue that Palestinians and others tactically use the space and networks surrounding the apartheid wall to reach transnational communities. While there are instances of Palestinian voices being amplified in transnational space, graffiti analysis also presents the overwhelming (ab)use of the wall by international actors to project their own (already amplified) voices and perspectives into transnational space, setting the stage for transnational dialogue on the surface of the wall. The wall is transnationalized in other ways, including the circulation of images of the wall and its graffiti, often by transnational actors with access to communications technologies. Historical analyses of graffiti in Palestine reveal that Palestinians tactically used graffiti in the first intifada to create national linkages in the absence of national institutions such as state media or state education.3 The presence of such nationalist graffiti on the walls of refugee camps and other places that do not entertain tourists, contrasted with the overwhelming presence of outwardly-focused, transnational messages on the separation wall, point to the tactical use of space to divert it from its intended purpose of separation, and create new meanings and linkages which challenge the structures of the occupation. …


High‐quality zircon U‐Pb ages acquired from Meso‐ and Neoproterozoic strata in North China in recent years has provided a high‐resolution chronostratigraphic framework for dating. A basis of this high‐level chronostratigraphic system provides the foundation for a global Precambrian study and stratigraphic correlation and so recent geological studies have focused attention on systemic SHRIMP zircon dating. A chronology of Meso‐ and Neoproterozoic strata and the time of origin of the overlying Changcheng System is given on the basis of new SHRIMP zircon dating from the Qianxi Complex and diabase of the Chuanlinggou Formation. A new tectonostratigraphy for a Neoproterozoic chronostratigraphic framework in the southeastern margin of the North China continent is underpinned by the new SHRIMP zircon dating of a Neoproterozoic mafic magma diabase in the Jiao‐Liao‐Xu‐Huai Sub‐Province.


Polymer multi-wall carbon nanotube (MWNT) composites were prepared and characterized as part of an effort to develop polymeric materials with improved combinations of properties for potential use in solar cell applications. Multi-walled carbon nanotube (MWNT) poly(3-hexylthiophene) nanocomposites were synthesized by in situ polymerization of monomers in the presence of different amounts of MWNTs. A process is reported to efficiently disperse multi-walled carbon nanotube (MWNT) bundles in a semiconducting polymer matrix. A uniform dispersion of the nanotubes in the polymer matrix was obtained. Characterization of the nanocomposites and the effects of MWNT concentration and dispersion on the structural, optical and electrical properties were discussed. FTIR and Raman spectroscopic investigations of nanocomposites indicate that the polymer is wrapped on the nanotubes, taking up a rigid orientation through π-π stacking. The Hall voltage measurement is followed to monitor carrier concentrations and mobilities, instead of the device fabrication and hole mobility measurements.


Discourses on the public understanding of science can make for some of the dullest and most confusing reading around. That is because they usually fail to grapple with the basic questions of what is represented by the words "science," "public," and "understanding." The images being conveyed are rarely obvious. For example, does "science" mean the fruits of scientific research? Does it mean the processes of doing research? Is science, in fact, a belief system that begs a definition? What does it mean to believe in "scientific progress" when defining progress itself is difficult enough? So when we engage active but dissimilar minds about the importance of popularizing science, we better don our armor and choose our ordnance for a clash of value systems. Oftentimes the public confuses science with its first cousin, technology. And just as often, science in its quest for support conveniently claims major credit for developments that were almost purely the work ...


With the development of high-throughput screening,the cell model plays a role in drug screening.The application of the cell model system in high-throughput drugs screening is riviewed,mainly focusing on the screening process of high-throughput screening based on the cell model,the classification of the cell model,related detective technique,and its development in future.


Rayleigh–Taylor instability of radiation pressure accelerated ultra-thin foils of different thickness profiles and initial curvature is investigated in two dimensions using numerical simulations. The convex curvature of the foil (when viewed from the rear side of the foil) provides radially inward motion to the off-axis ions countering the radial divergence due to the Gaussian intensity distribution of the laser. Nonuniform foils, having maximum thickness on laser axis have similar effect. When a small ripple is superimposed on the foil on the scale of laser wavelength, the radiation pressure acts nonuniformly on the microscopic scale and the perturbation grows as the foil moves. After a certain distance of travel, the foil crests turn into cusps and the phase of quasi mono-energy ion acceleration terminates. The planar foil with uniform laser has a strong growth of Rayleigh–Taylor instability (RTI). The foils with curvature and nonuniform thickness have marginally lower growth rate. However, under all circumstances, RTI is found to induce additional energy spread, in radiation pressure acceleration (RPA) of thin foils.


In fashion, there are various cultural aspects that exist in complexity, where according to the era, even fashion items newly develop and prevail into various designs in the organic function with reality of related cultural phenomenon and aesthetic aim. Among the fashion items, the shoe is historically considered as the shield from lust and also the provision of praise against the most emotional incitement. Mankind has started wearing shoes out of the functional purpose of protection since the ancient Egyptian times. Thereafter humankind has been creating shoes artistically in respect to shape, color, and quality of material, etc, as an expression of aesthetical awareness and introspective desire for beauty. As modern fashion increasingly regards the total fashion image much more important than each items consisting the whole outfit, the role of shoe became essential more than ever. Contrary to its relative importance, little academic attention was given to this area yet, while prestigious museums and galleries in Europe and the USA have held exhibitions of shoes in view of both historical and artistic aspects. This study aims to make a historical inquiry of western shoes, through which their aesthetic values can be drawn. Literature on this subject including aesthetics, history of costume and arts were referred. Fashion magazines and catalogues were investigated for additional information. The process and results of this study are meant to be a suggestion not only to further studies but also to artistic and creative shoe design. Originated for the functional purpose, shoes have evolved in various shapes with different meanings attached to it. When the technological development made the satisfaction for functional needs possible, the intrinsic attribute, the aesthetic value was pursued. The historical contemplations of shoes from Egyptian times to the 1990`s led to the results that the intrinsic aesthetic value of shoes can be summarized as follows: 1) protection and extension of body, 2) need for decoration, 3) erotic expression. 4) symbol of dignity and class, 5) fashion.


A non-logarithmic time dependence of the magnetization relaxation in superconductors is modeled by certain solutions of the nonlinear equation for flux diffusion, which can be derived either on the assumption of a logarithmic dependence of the pinning potential on the current density or, equivalently, a power-law current-voltage characteristic. Limiting cases of the spatiotemporal evolution of the flux density profile are identified: at one end of the parameters governing non-linearity the classical, linear processes relevant to the reversible part of the H-T diagram of high-T/sub c/ materials are found, whereas at the other end, a true critical-state behaviour emerges. Scaling relations between the sample size, magnetic field and characteristic relaxation times are established, which should characterize the magnetization relaxation process as well as the response to an AC field in susceptibility measurements. >


A protective shell of an RFID (radio frequency identification) tag comprises a first shell body, a second shell body, and a packaging structure, wherein the packaging structure is used for packaging the RFID tag in a holding space formed by the first shell body and the second shell body, and the first shell body is provided with a first extended portion. The first extended portion comprises at least one air-guide groove, an elastic body and at least one first air-guide through hole, each air-guide groove is provided with a cavity and an opening, the elastic body matches with each air-guide groove in shape and is inserted into the cavity of each air-guide groove to form an elastic clamping portion with the cavity of each air-guide groove, each first air-guide through hole is poisoned on the side wall, close to the elastic clamping portion, of the holding space, one end of each first air-guide through hole is communicated with the holding space, and the other end of each first air-guide through hole contacts with the elastic body. When the air pressure in the holding space is higher than the atmospheric pressure and reaches a preset threshold value, high-pressure air is extruded from each first air-guide through hole to force the elastic clamping portion to form an air-guide channel and is exhausted via the air-guide channel and each air-guide groove. By the protective shell of the RFID tag, a packaging product of the RFID tag can be resistant to high temperature and meet protection standards of IP68.


A promising approach to solving sparse systems of equations involves creating an augmented system that is symmetric quasi-definite. The attraction of this approach stems from being able to use powerful algorithms and efficient data structures that have been developed for sparse positive definite systems. In this article, bounds are derived for the condition number of the Schur complements that emerge when symmetric Gaussian elimination is applied to these quasi-definite matrices. An application of these bounds to solving regularized linear least squares problems is discussed. For the corresponding linear systems, the bounds may be used to justify a reordering based solely on sparsity preservation considerations.


The pregnant woman is subject to all surgical diseases of non-pregnant women and the surgical acute abdomen isn't an exception. It may to be considered within the medical pathology like one of the more severe and dramatic affections achieving a Revista Cubana de Obstetricia y Ginecología; 30(1)76-83 http://scielo.sld.cu 77 77 great significance when is present during pregnancy and frequently diagnosis of these patients must to be adjusted to care for worries in relation to a second patient: the fetus. An update review was made to expose the peculiarities of the biliary lithiasis disease in pregnancy since it is difficult for whom to make its study to find the subject developed with other problems and peculiarities; in his turn, to offer to all attracted by so fascinating subject, a guideline allowing to make an early diagnosis to avoid tragic consequences for mother and its future baby. We conclude that surgical technique to be used will depend on institution, training and preparation of surgeon, the severity of patient and the pregnancy trimester.


The results of the computational experiment, Show, that the dependence of the relatively carrying capacity on the relatively eccentricity is almost independent on the reinforcement Ratio or on and concrete type.


Three-phase line-start permanent magnet synchronous motors are considered among the most promising types of motors in industrial applications. However, these motors experience several faults, which may cause significant financial losses. This paper proposed a feed-forward neural network-based diagnostic tool for accurate and fast detection of the location and severity of stator inter-turn faults. The input to the neural network is a group of representative statistical and frequency-based features extracted from the steady-state three-phase stator current signals. The current signals with different numbers of shorted turns and loading conditions are captured using the developed finite element JMAG™ model for interior mount LSPMSM. In addition, an experimental set-up was built to validate the finite element model and the proposed diagnostics tool. The simulation and experimental test results showed an overall accuracy of 93.125% in detecting the location and the size of inter-turn, whereas, the accuracy in detecting the location of the fault is 100%.


LDH, one of the earliest marker still being used along with troponins in the diagnosis of acute myocardial infarction is now emerging as an important marker in a wide range of cancers. Recently LDH and its isoenzymes have been extensively studied in the detection and its prognostic role in common tumors such as colorectal, breast, ovarian, prostate, liver and various other metastases. LDH levels have been correlated with CEA, CA 15.3, CA 125,CA19.9 and Hodgkin's lymphomas. Further, isoenzymes of LDH are being studied extensively and each isoenzyme was found to be specific for a particular cancer. LDH has been linked to intracellular enzymes through damaged cells in apotoposis and deregulation. Studies suggest that inhibiting LDH activity may lead to possible anticancer treatment. The objective of this review article is to present the outcome of various research findings during the last two decades and to make awareness among research scholars to undertake further research to establish the exact clinical role of LDH in each type of cancer.


The amylase producing potentials of bacterial isolates associated with cassava peels obtained from five different locations within Delta State, Nigeria was investigated. The bacterial isolates were Bacillus subtilis, Bacillus megaterium, Micrococcus luteus, Streptococcus sp., Corynebacterium kutseri, Lactobacillus fermenti, Escherichia coli and Serratia marcescens. Amylase producing ability was screened for, using nutrient agar supplemented with 1%(w/v) starch. Results obtained revealed that B. subtilis, B. megaterium, C. kutseri and L. fermenti had α – amylase producing ability. Amylase activity increased progressively with increase in incubation duration and decreased as incubation temperature increased. Highest amylase activities were obtained at 25 minutes of incubation and at temperatures that ranged from 26 to 37 o C. Amylase activity reduced from 940 - 2.35 unit/ml (B. substilis), 535.8 – 2.35 unit/ml (B. megatarium), 211.5 – 2.35 unit/ml (C. kutseri) and 446.5 – 23.5 unit/ml (L. fermenti) as incubation temperature increased from 26 - 60 o C. Cassava peels regarded as waste can therefore be explored as source of amylase producing bacteria which could thus be applied in the production of


MEMS and NEMS provide a novel and exciting medium where one can observe and utilize mathematical phenomena not often present in macro-scale systems. By understanding thoroughly the dynamics of resonant MEMS, we can not only predict device behavior to eliminate unwanted effects, but also use nonlinear effects to design better sensors and systems. This paper describes two examples of utilizing and exploiting the parametric resonance instability to design micro and nano-scale resonant sensors. The first example discusses a class of sensors (pressure and mass) based on tracking a sharp bifurcation present in the system. The second example, based on a coupled mode parametric resonance, is a parametric amplifier, which has direct applications in communications (filters, switches, mixers) where high-Q, tunable resonant elements are essential.


The most recent outbreak of the highly infectious acute respiratory syndrome (SARS)-CoV-2 has grappled the world. Human behavior and awareness assessment during this crisis is crucial in an effort to contain the pandemic. Objectives: We conducted this study to assess evaluation of awareness, attitude, prevention, expectations, and precautionary measures against COVID-19 among the university students in Odisha. Methods: This is a comprehensive cross-sectional study that was conducted as an online survey using an online self-completed questionnaire. The participants were students enrolled in different universities in Odisha. The questionnaires were divided into four main sections: general health knowledge, sterilisation, prevention, and precautionary measures on COVID19. Results: Most of the students (85.8 %) believed that consuming antibiotics is not useful, 75.9% considered that washing hands with normal water is helpful and 61.8 % believed drinking a hot drink will help prevent COVID-19. Where 54.7% of participants followed the world health organization as the primary sources of information and 27.4% of the participants used social media to obtain information about (SARS)-CoV-2. Most of the participants (99%) agreed that self-isolation and maintaining distance can decrease the spread of COVID-19. The majority of the respondents had sufficient knowledge and their attitude and perception towards Covid-19 preventive measures was satisfactory. Conclusion: Odisha Universities students demonstrated an expected level of awareness about the COVID-19 virus and implemented effective strategies to prevent its spread.


To control the competition risk of a Build-Transfer project of subcontractor, of which the time to complete its subprojects is stochastic, the problem of partner selection is studied to maximize the completion probability of the project that is constrained by benefit of BT project and the precedence of its subprojects. Firstly, make a prompting policy on consruction period to subcontractor, describing on the basis of program evaluation and review technique, then, a PERT-embedded genetic algorithm is designed to solve the problem. Finaly, calculating the critical path and select subcontractor by example, the reaseach result provide a effective management implement for selecting subcontractor of BT project in stochastic cases.


Ai Siqi and Mao Zedong are the founders and pioneers of the application of Marxism in China.By meeting the demands of the common times and with their specific roles and standpoints,they achieved their own understanding and application and formed the essential framework,way of thinking and means.Their analyses have the immediate significance in the new application and creation of socialism with Chinese characteristics under new historical conditions so we should inherit and carry on this precious historical legacy.


WORKGROUP I-HIV-l ANTIBODY TESTING Keview and update antibody testing recotnmenclations from the first three consensus conferences. Should the consensus conference recommendations be modified to accommodate STA'I' testing? Address the applications of filter paper technology 111 human immunodeticiency virus (HIV) testing. Formulate an algorithm for testing Western blot indcterminants. Address the role of assays based on recombinant or synthetic proteins. What constitutes comparability atnong Western blot methods. Keexamine interpretive criteria for the Western blot. Identify research needs in the area of HIV-1 antibody detection.


The hydrology of wetlands located in urban landscapes is likely to be affected by the numerous effects of urban development on the water cycle. Although urbanization is affecting an increasingly large amount of wetland area, there have been few studies documenting hydrologic patterns in such wetlands. We have studied a set of 21 forested wetlands distributed through northeastern New Jersey, USA, a region characterized by dense residential and commercial development. The sites varied widely in area (6–500 ha), and all were bordered by urban land uses. In ten sites, water levels were monitored for 2.5 yr in shallow wells and piezometers; in all sites, qualitative indicators of hydrology, vegetation, and soil indicators of wetland hydrology were sampled. The sites were placed in five hydrogeomorphic (HGM) classes (depression, slope, riverine, mineral flats, and mineral flat-riverine) and also in three qualitative classes of hydrologic disturbance (low, medium, and high). We examined water-level dynamics, variability, the occurrence of discharge/recharge conditions, and the frequency of occurrence of hydrologic indicators across both HGM and disturbance classifications. Qualitative indicators of hydrology did not reveal differences in hydrology that were apparent from the quantitative data, the soils, and the vegetation. Mineral flat-riverine sites were the most wet, and the riverine sites the most dry, but hydrologic disturbance tended to blur distinctions among HGM classes by creating relatively dry conditions in most site types. Sites with a high level of hydrologic disturbance also tended to be more "flashy," regardless of HGM class. We conclude that the utility of HGM classifications and qualitative indicators of hydrology in urban/suburban landscapes are limited by the high degree of variability in both the extent and particularly the sources of hydrologic disturbance. We conclude that the hydrology of wetlands in an urban region reflects not only the hydrogeomorphic setting but also the unique set of disturbances from current and historical land-uses found at each site.


BACKGROUND AND OBJECTIVE
The association of chemotherapy-associated hemoglobin and survival of colorectal cancer (CRC) receiving adjuvant chemotherapy is uncertain. We sought to explore the prognostic value of chemotherapy-associated hemoglobin in CRC receiving adjuvant chemotherapy and the best cut point affecting prognosis.

METHODS
Three hundred and twenty stage II and III CRC patients receiving adjuvant FOLFOX chemotherapy from March 2003 to March 2012 were enrolled. The associations between chemotherapy-associated hemoglobin (the absolute levels of post-chemotherapy) or chemotherapy-associated hemoglobin change (change between the pre- and post-chemotherapy hemoglobins) and disease free survival (DFS) or overall survival (OS) of CRC, and the best cut point were investigated.

RESULTS
Log rank test showed the best cut points for chemotherapy-associated hemoglobin and chemotherapy-associated hemoglobin change were respectively 90 g/L, 30 g/L. Cox regression model showed chemotherapy-associated hemoglobin < 90 g/L was the independent prognostic factor for DFS (HR, 2.221; 95% CI = 1.157-4.262), OS (HR, 2.058; 95% CI = 1.009-4.197), respectively, but no association of chemotherapy-associated hemoglobin change ⩾ 30g/L and DFS (HR, 2.063; 95% CI = 0.929-4.583), OS (HR, 1.386; 95% CI = 0.553-3.471) was found.

CONCLUSIONS
Chemotherapy-associated hemoglobin < 90 g/L has a significant prognostic value in CRC receiving adjuvant chemotherapy, which is a significant biomarker in the individualized management and may suggest the simple indication for the treatment of anemia in adjuvant chemotherapy in CRC.


77Lu-DOTATATE, a radionuclide therapy which binds SST2A, has demonstrated efficacy in neuroendocrine tumors and evidence of CNS penetration, supporting potential expansion within pediatric neuro-oncology. Understanding the prevalence of SST2A expression across pediatric CNS tumors is essential to identify patients who may benefit from somatostatin receptor-targeted therapy and to further elucidate the oncogenic role of SST2A.

 SST2A immunohistochemistry (IHC) was performed on tumor specimens and interpreted by two experienced pathologists (blinded), utilizing semi-quantitative scoring of membranous expression within viable tumor. Immunoreactive cell percentage was visually scored as 0 (none), 1 (< 10%), 2 (10-50%), 3 (51-80%), or 4 (>80%). Staining intensity was scored as 0 (none), 1 (weak), 2 (moderate), or 3 (strong). Combined scores for each specimen were calculated by multiplying percent immunoreactivity and staining intensity values (range=0-12).

 A total of 117 tumor samples from 113 patients were analyzed. Significant differences in SST2A IHC scores were observed across histopathologic diagnoses, with consistently high scores in medulloblastoma (mean±SD=7.6±3.6 [n=36]) and meningioma (5.7±3.4 [n=15]), compared to minimal or absent expression in ATRT (0.3±0.6 [n=3]), ETMR (1.0±0 [n=3]), ependymoma (grades I-III; 0.2±0.7 [n=26]), and high-grade glioma (grades III-IV; 0.4±0.7 [n=22]). Pineoblastoma (3.8±1.5 [n=4]) and other embryonal tumors (2.3±3.8 [n=8]) exhibited intermediate, variable expression. Among expressors, there was no association between SST2A IHC score and patient age, sex, presence of metastases, likelihood of relapse, or prior treatment. In a subset of paired primary and recurrent specimens from 3 patients, SST2A IHC scores remained largely unchanged. Among medulloblastomas, SST2A IHC scores were higher in non-SHH (8.6±3.2) than SHH (5.0±3.3) molecular subgroups (p=0.033).

 High membranous SST2A expression was demonstrated in medulloblastoma, meningioma, and some rarer embryonal tumors with potential diagnostic, biologic, and therapeutic implications. Somatostatin receptor-targeted therapy such as 177Lu-DOTATATE deserves further investigation in these highly SST2A-expressing pediatric CNS tumors.


This study aims to investigate the structural behavior of concrete module joints under various compressive strength of concrete, configurations of shear key, and horizontal confining stress levels. The joint behavior, shear capacity, and crack patterns of dry joints in concrete module have been studied. Test results indicated that the shear capacity of joints increased as shear key inclination increased. In addition, shear capacity of concrete module joint increased with the increase of confining stress levels. The results obtained in these tests have been compared with design formulae for assessing the load-carrying capacity of dry joints.


The invention relates to a 'catalyst used for ammonia selective catalytic reduction of nitrogen oxides to nitrogen gas and a preparation method thereof', and belongs to the catalyst technical filed. The catalyst consists of V2O5-WO3/TiO2/BaO/gamma-Al2O3. The catalyst takes gamma-Al2O3 as a carrier, which increases specific surface area of the catalyst and lowers the catalyst carrier cost; BaO is added to protect the carrier against sulfation, reduce oxidization activity on sulfur dioxide and prolong service life of the catalyst; and titanium dioxide is highly dispersed on surface of the carrier, thus improving utilization rate of the titanium dioxide. The catalyst is characterized by low cost, high catalytic activity and very low activity to oxidize sulfur dioxide to sulfur trioxide.


Chimpanzees are remarkably social primates, grooming reciprocally, fighting in groups, and sharing the spoils of hunts. Yet whether chimpanzees engage in collective action and reciprocal cooperation when doing so exacts a toll remains unclear. Kevin Langergraber et al. (pp. 7337–7342) examined whether chimpanzees engage in collective action for group welfare when they incur costs and receive few immediate benefits. The authors analyzed behavioral and genetic data from a 20-year study of more than 140 chimpanzees, 13 years of age or older, at Kibale National Park in Uganda to uncover the motives underlying participation in boundary patrolling. During patrols, which last more than 2 hours and cover up to 2.5 km on average, groups largely composed of male chimpanzees visit the edges of their territories in a show of vigilance, sometimes killing neighbors. Patrolling is associated with heightened stress hormone levels and could exact a physiological toll on individual chimpanzees. Nevertheless, the authors found, males patrolled even when they had no offspring or maternal kin in the group. Overall group patrolling did not decline with group size. Because patrolling can augment group size and future reproductive success, the authors reason, group augmentation might explain chimpanzees' collective action in the absence of short-term benefits. The findings underscore the latent advantages of living in large groups. In a related article, Martin Schmelz et al. (pp. 7462–7467) tested whether chimpanzees engage in a form of quid pro quo. The authors trained six chimpanzees housed at a primate research center to participate in an experiment that involved choosing between a social option, which delivered food both to themselves and a partner, and a selfish option, which delivered food only to themselves. When players in the experiment had previously witnessed partners appearing to provide assistance in obtaining food, they were more likely to make a social rather than a selfish choice—even when the selfish option would have meant a higher food reward for themselves. Chimpanzees were also sensitive to whether partners that appeared to assist them did so at risk of losing food, suggesting that players' social acts were a considered response to partners' perceived social acts. If confirmed in larger studies that include other social primates, such as bonobos, the findings might illuminate the seemingly deep evolutionary roots of human cooperation, according to the authors. — P.N.


Abstract 2547 Poster Board II-524 Hematopoietic stem cells (HSCs) are bone-marrow derived, self-renewing pluripotent cells that give rise to terminally differentiated circulating blood cells. Recent work has implicated HSCs in the repair of parenchymal tissue in the setting of inflammation. In response to the antagonist of the chemokine receptor CXCR4, HSCs and their progenitors migrate from bone marrow to the blood. However, little is known about the signals that mediate their trafficking from the blood into peripheral tissues. Recently, we showed that mice genetically deficient in chemokine receptor CCR2 (CCR2–/– mice) have a marked decrease in the number of circulating "inflammatory" (7/4+, Ly6c+) monocytes, but no decrease in myeloid progenitor cells in the bone marrow (Tsou et al, J Clin Invest, 2007, 902). These data indicated that although CCR2 is not necessary for HSCs to differentiate into mature monocytes, it does play a role in monocyte egress from bone marrow to blood. In the current study, we extend this work and investigate the expression of CCR2 on hematopoietic stem cells and progenitor cells (HSPCs), and tested the hypothesis that CCR2 is critical for the recruitment of circulating HSPCs to sites of inflammation. Here we report that the chemokine receptor CCR2 is expressed on subsets of primitive hematopoietic stem cells as well as some early myeloid progenitors but not on the progenitors dedicated to megakaryocyte and erythroid differentiation. CCR2 mediates the chemotaxis of c-Kit+Lin- bone marrow derived cells to MCP-1 (CCL2) and MCP-3 (CCL7), which are known CCR2 ligands. In unchallenged mice, CCR2 appears to play a minimal role in HSCs trafficking. However, following instillation of thioglycollate to cause aseptic inflammation HSPCs were actively recruited to the peritoneum, as demonstrated by both FACS and functional colony formation assays. That these cells were true HSCs was demonstrated by their engraftment into the bone marrow of irradiated recipients. In contrast, mice genetically deficient in CCR2 (CCR2−/−) were profoundly impaired in the recruitment of HSCs to the inflamed peritoneum. Furthermore, in human disease models of acetaminophen induced liver damages, hematopoietic stem and progenitors were increased dramatically at site of injury in WT mice but not in CCR2−/− mice. CCR2 recruited HSPC play a tissue protective role by increase the numbers of M2 macrophages in injured liver. Taken together, these findings document a novel role for CCR2 in the specific homing of primitive hematopoietic stem and progenitors to sites of inflammation and injury, and suggest a new role for chemokines in increasing the numbers of differentiated leukocytes at sites of inflammation. Recruited HSPCs hasten the resolution of the inflammatory response, and promote repair of injured tissue, at least partially due to locally increase the number of tissue reparative macrophages. Disclosures: No relevant conflicts of interest to declare.


Content Based Image Retrieval (CBIR) systems attempt to allow users to perform searches in large image repositories. Content-Based Image Retrieval (CBIR) has become one of the most progressive research areas in the past few years. In content Based Image Retrieval, images are retrieved based on color, texture and shape (low level perception). There is a gap between user semantics (high level perception/concepts) and low level perception is called 'Semantic Gap'. Relevance Feedback (Relevance Feedback) learns association between high level semantics and low level features. While these research efforts establish the basis of CBIR, the usefulness of the proposed approaches is limited. Specifically, these efforts have relatively ignored two distinct characteristics of CBIR systems are semantic gap and human perception of visual content respectively. In this paper, we propose different aspects of the system such as first, we analyze the nature of the Relevance Feedback problem in a continuous representation space in the context of image retrieval. Secondly, a Relevance Feedback based interactive retrieval approach, which effectively takes into account the above two characteristics in CBIR. During the retrieval process, the user's high level query and perception subjectivity are captured by dynamically updated weights based on the user's feedback and finally, the proposed system where user can view/understands the relevance level of the retrieved result of images to his/her given query image. The proposed approach greatly reduces the user's effort of composing a query and captures the user's information need more specifically. We can reduce the user intervention in the CBIR retrieval system.


The 3-year PREPARE project that started in February 2013 aims to close gaps that have been identified in nuclear and radiological preparedness in Europe following the first evaluation of the Fukushima disaster. Among other issues, the project will address the review of existing emergency preparedness and response procedures for dealing with long-lasting releases, cross-border problems in monitoring and food safety, and further develop missing functionalities in decision support systems ranging from improved source term estimation and dispersion modelling to the inclusion of hydrological pathways for European water bodies. In addition, as the management of the Fukushima event in Europe was far from optimal, a so-called Analytical Platform will be developed exploring the scientific and operational means to improve information collection, information exchange and the evaluation of such types of disasters. This will be achieved through a collaboration of industry, research and governmental organisations in Europe, taking into account the networking activities carried out under the NERIS-TP project. Furthermore, the NERIS Platform member organisations (so far 50 partners) will be actively involved in the development of the new tools.


The interaction of fluvial geomorphology evolution and special geological environment in horizontal formation in Wanzhou district resulted in its unique stepladder geomorphic feature.Based on a systematic field investigation,exploration and data collection,combining with the drilling at Shanwan pond in 2008,we conducted a comprehensive study of its sediment for the first time,systematically collecting sediment samples,doing analysis to determine its age and composition.It shows the consistency of Shanwan cliff collapse and the regional tectonism.The sediment profile of Shanwan landslide collapse deposit at each stage is presented and it is divided into 10 cycles of failure.Combining with the sediment dating,the deposition rate of Shanwan landslide sediment is researched,and the recession rate of Shanwan cliff is proposed as 0.31-0.37 m/ka.


Mechanical test data are reported on lap joints and tensile test specimens which have been subjected to a defined post cure cycle. The mechanical properties exhibited an apparently systematic variation with temperature. Inspection of the resins indicated that chemical modification does not appear to occur to a significant extent below 433K. The change in the strength of the joints tensile test samples are discussed in terms of the relative importance of physical and chemical changes on the mechanical properties. It is evident that in the presence of oxygen considerable chemical modification can occur and this is observed both in terms of a change in colour of the resin and the appearance of voids.


Haurwitz (1947) has shown in a highly simplified linear model of sea and land breezes that the wind holographs always rotate clockwisely in the northern hemisphere due to the Coriolis effect. Observed wind hodographs at many stations show the clockwise rotation (CR) in agreement with this theory, but there are also many stations where wind hodographs show the counterclockwise rotation (CCR) (e.g., Ito and Kawazoe, 1983; Shiraki, 1984b). The cause of CCR has not been clear for a long time. However, recently, Kusuda and Alpert (1983) presented that CCR can be produced under certain conditions through an extention of Haurwitz's linear model including a more complex forcing term. The complex forcing term in this theory corresponds to the complex distribution of differential heating generated by the topography. We analyzed sea and land breezes in the Kanto plain using surface wind data, and we found systematic CCR of wind hodographs in certain places in the present study. We show that this observational result can be explained by the superposition of two hodographs with both CR of sea breeze, lake breeze or terrain forced slope wind. This result suggests that the idea by Kusuda and Alpert (1983) can be applied to the sea and land breezes in the Kanto plain.


Apples belong to the group of fruits most susceptible to contamination with mold P. expansum. The consequences of the infection are reflected in the short-term economic losses, and the contamination of the fruits by this mold causes the accumulation of patulin in the poles, a mycotoxin whose role in causing the disease has not yet been fully elucidated. There are currently no satisfactory solutions in the world to reduce the concentration of patulin in apples and apple products. However, compared to commercial apple varieties, traditional varieties have higher proportions of polyphenolic compounds, important factors in plant protection against stress conditions, higher antioxidant activity, and a gene profile that makes them more resistant to climatic conditions, plant diseases and other forms of abiotic stress. The aim of the study is to examine the resistance of traditional apple varieties to the P. expansum colonization and the produced patulin concentrations, to determine potential differences, depending on the variety and the particular polyphenolic profile of the apple variety. Results showed that polyphenolic profile is very important for resistance on colonization by P. expansum. Despite to simmilar measured total poliphenol content valueas, as well as antioxidative activity there are some differences in P. expansum growth and patulin production observed. Apple variety 'Zlatna zimska pramenka' showed the highest resistace to patulin production, but also contain the highest observed cathechine concentration, high total poliphenol content and antioxidative activity. Such results indicate that resistance to P. expansum colonization could be modulated by total poliphenol content. However, further research should be carried out for scientiffic opinion establishing.


It is not enough only by the administration and economy method for lake harness synthetically. We must depend on local people surrounds the plateau lakes, mobilize, propagate and educate them to promote their environmental protection consciousness, so that they can participate in the synthetic lake harness of their own motion and the prospective harness effect can be approached.


KUALA LUMPUR: All Malaysians are advised to spend quality time with their families and to communicate and pay extra attention to their children's feelings and requirements, so that they will not easily be influenced by negative elements. Prime Minister Datuk Seri Najib Tun Razak said cooperation from all quarters was vital to ensure that the Malaysian society would be free from threats of drugs, and that Malaysian children would grow up as a competitive and successful generation.


We investigate computationally two representative examples of higher fluorides of Ag(II), namely KAgF3 and AgFBF4. Both compounds formally contain linear (Ag–F)+ chains, in which divalent silver is coordinated additionally by four fluoride anions. For AgFBF4, the equatorial coordination is weak, and leads to metallic conductivity in 1D, as emerges from our band structure calculations. For KAgF3, however, the axial coordination is very strong, and the compound is virtually a 2D metal (i.e. it is mainly the x2–y2 orbitals of Ag that participate in electronic transport in this interesting material). (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


The traditional power systems are statically rated and sometimes renewable energy sources (RES) are curtailed in order not to exceed this static rating. The RES are curtailed because of their inter ...


Abstract Recent recommendations for control of nickel carbonyl exposures have been considered in the design of a simple, sensitive field method for sampling nickel carbonyl in air and process gases. The method involves collection in dilute aqueous HCI, pH adjustment, nickel complex development with alpha-furildioxime, and extraction with chloroform. Color intensity is compared visually (or for greater accuracy, spectrophotometrically) with liquid standards. Sensitivities on the order of 0.001 ppm are obtainable. A detailed development of the thermodynamics associated with the formation of nickel carbonyl is also presented to show the maximum concentrations of nickel carbonyl that may be formed over a wide range of CO concentrations, temperatures and pressures.


A study was conducted to standardize the method of in vitro propagation of carnation. As regards suitability of explants, shoot tip and nodes were the best for culture establishment, by producing more number of adventitious shoots in a shorter period of time. 'In vitro proliferated shoots were subcultured on MS medium with BAP and kinetin at different concentrations. The highest number of multiple shoots and fresh weight were observed on 20 uM BAP/1. But the shoots showed vitrification. The shoots proliferated on kinetin containing media were healthy and normal. But on medium without cytokinins, single shoots of maximum length were produced. Also when BAP and kinetin were combined with NAA at different concentrations higher number of multiple shoots were observed. NAA at higher concentration showed vitrification and also reduced the length of the shoots. Rooting of microshoot was induced on half strength MS medium with different levels of auxins and rooting was observed even in auxin free medium. Maximum number of roots with better shoot and root characters were observed on medium with 5 uM NAA/1. NAA at higher concentration proved to be detrimental to root growth by suppressing its growth. Soilrite (TC) medium gave the highest survival percentage at 15 and 30 days after transfer to hardening media and plantlets so hardened were also more vigorous.


newdoppler.m is the main matlab file.other functions are called from the main function i.e, newdoppler function. Report is also submitted along.


There is provided an apparatus for homogenizing and / or dispersing flowable, especially liquid or paste-like substances as underlying material, which comprises a container for the underlying material and a motor-driven homogenising and / or dispersing device. The underlying material is conveyed by a vessel outlet by means of a feed pump for homogenizing and / or Diespergiereinrichtung which entry device for additives in liquid and powder form are optionally associated. The homogenizing and / or dispersing device allows optionally the outlet, a return flow into the container. According to the invention the feed pump is shown separately for homogenizing and / or dispersing device is driven, and it is a sensor, preferably a pressure sensor disposed between the pump outlet and the inlet side of the homogenising and / or dispersing device. The sensor controls the separate drive of the delivery pump variably according to the flow properties of the underlying material and / or appropriate process parameters, such that the product stream guide for homogenizing and / or dispersing device is always pre-pressurisation.


Sexual health is an under-explored area of Human-Computer Interaction (HCI), particularly sexually transmitted infections such as HIV. Due to the stigma associated with these infections, people are often motivated to seek information online. With the rise of smartphone and web apps, there is enormous potential for technology to provide easily accessible information and resources. However, using online information raises important concerns about the trustworthiness of these resources and whether they are fit for purpose. We conducted a review of smartphone and web apps to investigate the landscape of currently available online apps and whether they meet the diverse needs of people seeking information on HIV online. Our functionality review revealed that existing technology interventions have a one-size-fits-all approach and do not support the breadth and complexity of HIV-related support needs. We argue that technology-based interventions need to signpost their offering and provide tailored support for different stages of HIV, including prevention, testing, diagnosis and management.


The structural characteristics of loess will change due to carbonate dissolution when loess is exposed to acid rain, industrial acid leakage and other acidic environments. The change of compressive yield well Characterization the initial structure of loess. To analyze the effect of initial water content on compressive yield of loess, confined compression tests and uniaxial compression strength tests were conducted on loess soils of five sets of water content, and the calculating method of compressive yield stress are given. The results show that the compression data of loess conform to the Gompertz equation, and the method to determine the maximum curvature point is given, which provides a new method to calculate the compressive yield stress.With the increase of initial water content, loess enters the compression yield state under lower water content, resulting in the failure of loess structure. This paper will contribute to elucidating the of loess.


Low pressure capacitively coupled radio frequency plasmas (cc‐rf plasmas) were investigated by minimalinvasive 160 GHz Gaussian beam microwave interferometry. The interferometer is a frequency stabilized (PLL) heterodyne system which immediately provides the line integrated electron density at spatial (axial) resolution of about 10 mm and temporal resolution of 200 ns. The line integrated electron density was measured in dependence on the processing parameters rf power (10 … 100 W) and total pressure (10 … 100 Pa) in comparison between argon and oxygen. Thereby, the changed distance between the fixed microwave beam axis as well as the sheath edge is taken into consideration using an analytical collision‐dominated sheath model and results from optical emission spectroscopy. Microwave, interferometry and simultaneous laser photodetachment in oxygen plasma additionally permits the measurement of the negative atomic oxygen ion density. Dynamic and transient phenomena in oxygen plasmas are discussed such as mode transitions, afterglow behaviour in pulsed rf plasma, and electron density fluctuations due to attachment‐induced ionization instabilities (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)


In the latest news of the Kuznets Environmental Curve it has been one of the most debated theories in environmental economics, as it explores the relationship between the variables economic growth and the quality of the environment. in the environment, and in the long term, when they are richer, their economic growth is beneficial for the environment; Based on the empirical evidence, the validity of the proposed hypothesis of the Kuznets Curve for Colombia in the period of 1971 2014, the writing of non-stationary time variables through a VAR model is evaluated; accompanied by tests of unit roots and cointegration. Finally, empirical evidence is presented demonstrating the existence of an environmental Kuznets curve for Colombia, which shows that increases in GDP per capita increase CO2 emissions, decrease from a certain level of GDP, but from an increase in the level of GDP CO2 the emissions grow


Plant unavailability associated with primary and secondary holes is approximately the same as that caused by steam generator tube defects, i.e., 0.5%. Problems encountered with steam generator man-, hand-, and eyeholes during plant operation have led Electricite de France (EdF) and Framatome to improve hole seal design and to develop robots for closing and cleaning them. The data base available in France in this field on some 150 steam generators in 900- and 1300-MW(electric) pressurized water reactors (the equivalent of 300 reactor-yr of operation) has been the base of the developments described in this paper. Incidents occurring in operation primarily concern had-and inspection holes located on the steam generator's secondary side. They include four kinds: (1) leakage detected in operation, requiring forced outages, (2) leakage detected during plant restart after a scheduled shutdown and resulting in a restart delay, (3) pitting of seal mating surfaces, not inducing any leakage but jeopardizing subsequent compliance and requiring difficult and costly repairs, and (4) seizing of screws or bolts. New primary and secondary hole stud tightening and maintenance machines help to improve the efficiency of the in-service closing operations. They provide savings of up to 80% on labor, duration of operations, and exposure.


Certain sexual disorders are under-reported, under-researched, and rarely discussed. Many patients have suffered from ailments such as vulvodynia, a subset of vulvodynia called vestibulodynia, post-orgasmic illness syndrome (POIS), and interstitial cystitis (IC) without clear and optimal treatment strategies. To bring more awareness to these conditions, researchers and other medical professionals are working to elucidate their pathophysiologies in order to provide patients with therapeutic solutions. Mast cell dysfunction is one proposed mechanism of disease for these conditions. Mast cells are CD34+/CD117+/CD13 pluripotent progenitors of hematopoietic stem cells. They serve as innate immune cells that play a significant role in allergic responses, inflammation, and tissue homeostasis. They undergo maturation via growth factors and interleukins in the periphery and are heavily implicated in processes such as anaphylaxis, arthritis, coronary artery disease, autoimmune disorders, and cancer. As the body of research grows surrounding the function of mast cells and mast cell activation, researchers are finding that they may be implicated in multiple disease processes, even in genitourinary disorders. We know little about the etiology of disorders that affect sexual function like vulvodynia, POIS, and IC, but when considering their inflammatory and/or allergic-type symptoms, such as itching, burning, and congestion, we hypothesize that their pathophysiology may be correlated to mast cell function impairment.

 The purpose of this study is to determine if mast cell dysfunction correlates with the pathophysiology of vulvodynia, POIS, and IC based on a literature review.

 The authors reviewed existing literature published from January 2010 - June 2022 that explored the histopathological, pathophysiological, and etiological nature of vulvodynia, POIS, and IC. The selection criteria for this narrative review included: original articles (randomized and non-randomized clinical trials, including prospective observational studies, retrospective cohort studies, and case-control studies), review articles, and Cochrane analyses concerning the relationship between sexual disorders and allergens and/or immunology. Eighteen articles met the inclusion criteria.

 From the studies evaluated, it is reasonable to infer that vulvodynia, POIS, and IC have an immunological component to their pathophysiology. The inflammatory nature of all the diseases above indicates a definite immunological involvement, but as more research emerges, several medical providers and authors alike are noting that immunology and, certainly, mast cells may play a more significant role than initially hypothesized. While mast cells are likely not the sole cause of disease, it would be in the patient's and provider's best interest to consider their involvement in multifactorial pathophysiology for sexual disorders.

 The pathophysiology of sexual disorders like vulvodynia, POIS, and IC is not currently well understood. However, review of existing literature supports that mast cell activation and, to a lesser extent, Toll-like receptors (TLRs) and lymphocytes may play a cardinal role in the pathophysiology of the sexual disorders described. Further research needs to be conducted on the possible pathophysiology of sexual disorders broadly so healthcare practitioners can provide effective, evidence-based treatment that will provide patients optimal relief.

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The whisker map in rodent somatosensory cortex is well characterized under anesthesia, but its organization during awake sensation, when cortical coding can differ strongly, is unknown. Using a novel behavioral task, we measured whisker receptive fields and maps in awake mice with 2-photon calcium imaging in vivo. During a whisker-attentive task, layer 2/3 pyramidal neurons were sharply tuned, with cells tuned to different whiskers intermixed in each column. This salt-and-pepper organization consisted of small clusters of similarly-tuned neurons superimposed on a mean subcolumnar map. Parvalbumin interneurons had broader tuning, and were more homogeneously tuned to the columnar whisker. During a sound-attentive task, whisker tuning of pyramidal cells was less heterogeneous in each column, and firing correlations increased. Thus, behavioral demands modulate fine-scale map structure, and decorrelate the whisker map during whisker-attentive behavior.


accompaNyiNg article See pp 1166–1172. DOI: 10.3171/2015.1.JNS132842. iNclude wheN citiNg Published online February 27, 2015; DOI: 10.3171/2014.6.JNS141129. disclosure Dr. Schwartz owns stock in Visionsense. He is also a consultant for Karl Storz, and receives support for a non–study-related clinical or research effort from the NIH. In their article, Gu et al.9 introduce a seemingly minor but actually quite important nuance to the endonasal endoscopic approach (EEA). To understand the significance of their report, one must first review a bit of the history of transsphenoidal craniopharyngioma surgery. In the decades before the modern "endonasal endoscopic" era, the transsphenoidal route was thought to be safe for removing subdiaphragmatic craniopharyngiomas.5 These tumors were anatomically similar to pituitary tumors and well suited for the microscopic transsphenoidal approach. Once the transsphenoidal approach was extended through the tuberculum sellae, the application of the approach became suitable for tumors with supradiaphragmatic extension, although many of these were still mostly subdiaphragmatic and the sella was generally invaded with tumor and enlarged, which facilitated the approach.2,14 With the development of the extended EEAs, the transsphenoidal corridor could be used to remove purely supradiaphragmatic tumors above a normal-sized sella.3,6,7,10,12 These tumors were often within the confines of the third ventricle, or purely intraventricular, as were the tumors described in this article. In recent years, several groups have published their experience with removing supradiaphragmatic, third ventricular craniopharyngiomas by using an EEA, and in skilled hands the results are quite good—arguably better than those achievable with a transcranial approach.11 However, the corridor used to remove these tumors, although supradiaphragmatic, is generally infrachiasmatic. The reasons the infrachiasmatic corridor is used are multiple. The tumor generally takes its origin from the pituitary stalk, which is an infrachiasmatic structure. The chiasm is often pushed upward and forward by the tumor, so the endonasal trajectory takes the surgeon under the back of the chiasm into the third ventricle. Finally, it has been written in the literature that "This route minimizes the risk of postoperative visual loss, which is strictly related to the integrity of the vascularization of the optic chiasm. In fact, at this level, most of the blood supply to the optic system comes from the superior surface, from the branches of the anterior cerebral artery (ACA) and anterior communicating artery (ACoA), thus rendering the inferior approaches less dangerous than the transcranial routes."4 Herein lies the crux of the infrachiasmatic argument—that it is safer due to the origin of the vascular supply to the chiasm, which they presumed arose from above, namely from the ACA and the ACoA. However, as we will show, this presumption is fallacious. Indeed the vascular supply to the chiasm is extremely variable and arises both from above and below the chiasm, but the majority of the blood supply to the central part of the chiasm arises from below, from the ophthalmic portion of the internal carotid artery (ICA), as the ascending branches of the superior hypophyseal artery (SHA) and other small perforators that form a rich anastomotic network of vessels. Probably the most classic article on the blood supply to the chiasm was written in 1969 by Richard Bergland and Bronson Ray at Cornell–New York Hospital.1 In this paper, the authors use 480 autopsy specimens and demonstrate that the supply from the ACAs above the chiasm only feeds the lateral chiasm. In contrast, the supply from below, mainly from the SHAs, feeds the midline chiasm. These results supported their claim that the classic bitemporal hemianopia resulting from pituitary tumor growth pushing upward on the chiasm may not be entirely compressive but may also have a vascular origin. Later work by Al Rhoton mostly confirms these original observations, with a few small novel observations. In his article editorial Does chiasmatic blood supply dictate endonasal corridors?


This paper begins with a review of the broad motivations behind the New Public Sector Management (NPSM), including intrinsic differences between public and private organizations that appear to impact on incentives and performance. The experience in selected OECD countries is reviewed where the financing and delivery of health and other social services is heavily socialized with a strong public sector role, taxpayers have expressed dissatisfaction with traditional modes of public sector management, and NPSM reforms have been hotly debated. Part II of the paper then describes the NPSM paradigm in terms of three building blocks that influence the performance of public agencies and the behaviors of employees who work for them. It explains how leverage points within the NPSM paradigm are expected to create incentives for improved performance. It is when all three building blocks of the NPSM paradigm work together that synergies are expected to take place, and that continuous improvements in the performance of public agencies are expected to be generated over time. Part III illustrates five organizational strategies that can be used to introduce NPSM into public agencies in the national health system. Much of Part III refers to developing country applications.


The study of the biological effect of a localized x radiation on a mammal requires the establishment of a precise and rational test of effects. The physiological conditions under which counting of the cells in the femur bone marrow of the rat and the experimental set-up to give well-defined localized irradiations are described. The side effects are caused either by tue action of corticoid hormones or by scattered radiation. These two factors can be sufficiently reduced to obtain a pure radiological effect. Under such conditions the irradiation, even at high doses, has no perceptible distance-action. Irradiation of the adrenals induces an important decrease of cells of the femoral bone marrow, analogous to that produced by stress.'' Irradiation of other body segments has no effects on animals that have previously received an adequate dose of morphine. It is possible to observe the biological effect of irradiation in its pure form'' and to define the effect of precise radiation doses. (J.S.R.)


Job Analysis is a formal organizational document containing a summary of important information about a position to make it easier to distinguish one position from another in an organization. The job analysis is arranged in a structured format so that the information is easily understood by all parties involved in an organization. In essence, job analysis is a basic raw material in HR management in an organization, where a position is explained and given boundaries. This study aims to find out job analysis (X) has a significant effect on performance (Y) at SMK Pertiwi Sukamandi which takes a population of teachers and staff of 107 respondents. While the method of data collection method used is to use a questionnaire (Survey) on all teachers and staff of SMK Pertiwi Sukamandi. The methods used to process and analyze the data are validity test, reliability test, simple linear regression analysis, correlation coefficient analysis, coefficient of determination analysis and hypothesis testing. The results of the study show that job analysis has a positive effect on performance, it can be interpreted that the proposed hypothesis is accepted.


Canine heartworm disease is a potentially deadly cardiopulmonary disease caused by the mosquito-borne filarial nematode Dirofilaria immitis . In Australia, the administration of 27 macrocyclic lactone (ML) drugs has successfully reduced the prevalence of D. immitis 28 infection. However, the recent re-emergence of D. immitis in dogs in Queensland, Australia 29 and the identification of ML-resistant isolates in the USA poses an important question of 30 whether ML-resistance has emerged in this parasite in Australia. The aim of this study was to 31 utilise phenotypic and genotypic assays to determine the presence of ML-resistant D. immitis 32 in Australia. To do this, we surveyed 45 (n=45) dogs from Queensland and New South Wales 33 across 3 years (2019-2022) for the presence of D. immitis infection using an antigen test, 34 quantitative Modified Knott's test, and qPCR targeting both D. immitis and the D. immitis 35 symbiont Wolbachia . A phenotypic assay utilising a microfilarial suppression test for 23/45 36 dogs was coupled with genetic testing of filtered microfilariae for SNPs previously associated 37 with ML-resistance in isolates from the USA. Sixteen (16/45) dogs tested positive for D. 38 immitis infection despite reportedly receiving 'rigorous' heartworm prevention for 12 months 39 prior to the study. The phenotypic and genotypic assays in this study did not unequivocally 40 demonstrate the presence of ML-resistant D. immitis in Australia. Although the failure of 16 41 dogs to reduce microfilaremia by >90% after ML treatment was considered phenotypic 42 evidence of suspect ML-resistance, no genotypic evidence was discovered using the genetic SNP analysis. It is possible that the presence of ML-resistance in this study was masked by the high initial of moxidectin (microspheres, 500 µg/kg s.c.) administered to eighteen 45 (18/23) dogs at the time of diagnosis, which had the potential to clear any ML-resistant D.


Quantitative validation studies of flux-tube gyrokinetic Vlasov simulations on ion and electron heat transport are carried out for the JT-60U tokamak experiment. The ion temperature gradient (ITG) and/or trapped electron modes (TEM) driven turbulent transport and zonal flow generations are investigated for an L-mode plasma in the local turbulence limit with a sufficiently small normalized ion thermal gyroradius and weak mean radial electric fields. Nonlinear turbulence simulations by the GKV code successfully reproduce radial profiles of the ion and electron energy fluxes in the core region. The numerical results show that the TEM-driven zonal flow generation in the outer region is more significant than that in the core region with ITG- and ITG–TEM-dominated turbulence, leading to moderate transport shortfall of the ion energy flux. Error levels in the prediction of the ion and electron temperature gradient profiles in the core region are estimated as less than ±30%, based on a multiple flux matching technique, where the simulated ion and electron energy fluxes are simultaneously matched to the experimental values.


Background: Carpal Tunnel Syndrome (CTS) is a nerve disorder where an entrapped
median nerve in the carpal tunnel causing pain and numbness in hand. Prolonged
condition of CTS will decrease someone's productivity at job that required hand. The
worker of "X" furniture manufacturing work more than 8 hours a day by repetitive
hand movement with loads.
Objective: To identify the prevalence and risk factors of suspected CTS among
worker of "X" furniture manufacturing
Material and Method: A quantitative study using a cross sectional method was
conducted in August 2018. A number 47worker of "X" furniture manufacturing in
Gresik, East java, counted as samples that were obtained by total sampling technique.
The data were taken by questionnaires and checked using Phalen's test. The
correlation between the risk factors variables with suspected Carpal Tunnel Syndrome
(CTS) such as age, gender, work period, and work units were analyzed using chisquare
test.
Result: Based on the research, as much as 15 people (31.9%) were found having
suspected CTS. Based on chi-square test, the significancy value between suspected
CTS with the risk factor are: work period (p=0.042), work units (p=0.800), age
(p=0.899), and gender (p=0.961).
Conclusion: There is a correlation between suspected CTS with work period
(p<0.05) and there is no significant correlation with age, gender, and work units
(p>0.05) risk factors.
Keywords: Carpal Tunnel Syndrome, Median nerve, Industry Worker, Occupational
Health and Safety (OHS)


Let Ibe a nonpseudocompact space which is either nowhere ccc or nowhere of weight < 2". Then ßX — X contains a point x which is a weak /°-point of ßX, i.e. ii F C ßX — {x} is countable, then x & F. In addition, under MA, if X is any nonpseudocompact space, then ß X — X contains a point x such that whenever F C ßX — {x} is countable and nowhere dense, then xif. 0. Introduction. All spaces are completely regular and X* denotes ßX — X. Frolik's [F] proof that the Cech-Stone remainder of a nonpseudocompact space is not homogeneous is elegant and ingenious, but does not give points which are topologically distinct by an obvious reason. When Kunen [K.] proved that there are Rudin-Keisler incomparable points in ßo3, Frolik's ideas were used by Comfort [C] and van Douwen [vD2] to show that, respectively, no infinite compact space in which countable discrete subspaces are C*-embedded is homogeneous and that ßX is not homogeneous for any nonpseudocompact space X. These results showed that certain spaces are not homogeneous but not "why" they are not homogeneous. This suggests an obvious question which has been considered by several authors during the last years. The first promising partial answers to this question were obtained by van Douwen [vD3], who showed that each nonpseudocompact space of countable it-weight has a remote point (independently, this was also shown by Chae and Smith [CS]), and that remote points can be used to show that certain Cech-Stone remainders are not homogeneous. Unfortunately, it was soon clear, by examples in van Douwen and van Mill [vDvMJ, that this line of attack did not solve the entire problem, since many spaces do not have remote points. Earlier, van Douwen [vD.] had introduced far points and w-far points and showed that these points exist in certain Cech-Stone remainders and that they also could be used to show that a restrictive class of Cech-Stone remainders is not homogeneous. Each remote point is a far point and each far point is an w-far point when we restrict our attention to spaces without isolated points. When it was shown that not every nonpseudocompact space has a remote point, van Douwen's [vDJ question whether every nonpseudocompact space without isolated points has an w-far point again became interesting. The examples in [vDvM,] did not clarify this question since they all have far points. From [vDvM2] it Received by the editors November 12, 1980 and, in revised form, June 24, 1981. 1980 Mathematics Subject Classification. Primary 54D35.


Amyloid fibrils of patients treated with regular hemodialysis essentially consists of β2‐microglobulin (β2‐m) and its truncated species ΔN6β2‐m lacking six residues at the amino terminus. The truncated fragment has a more flexible three‐dimensional structure and constitutes an excellent candidate for the analysis of a protein in the amyloidogenic conformation. The surface topology of synthetic fibrils obtained from intact β2‐m and truncated ΔN6β2‐m was investigated by the limited proteolysis/mass spectrometry approach that appeared particularly suited to gain insights into the structure of β2‐m within the fibrillar polymer. The distribution of prefential proteolytic sites observed in both fibrils revealed that the central region of the protein, which had been easily cleaved in the full‐length globular β2‐m, was fully protected in the fibrillar form. In addition, the amino‐ and carboxy‐terminal regions of β2‐m became exposed to the solvent in the fibrils, whereas they were masked completely in the native protein. These data indicate that β2‐m molecules in the fibrils consist of an unaccessible core comprising residues 20–87 with the strands I and VIII being not constrained in the fibrillar polymer and exposed to the proteases. Moreover, proteolytic cleavages observed in vitro at Lys 6 and Lys 19 reproduce specific cleavages that have to occur in vivo to generate the truncated forms of β2‐m occuring in natural fibrils. On the basis of these data, a possible mechanism for fibril formation from native β2‐m is discussed and an explanation for the occurrence of truncated protein species in natural fibrils is given.


1.1. Let k be a local field of characteristic 0, i.e. R, C or a finite extension of Qp. If k is p-adic, we denote by O ⊂ k the ring of integers in k, p ⊂ O the maximal ideal, and $ ∈ p a uniformizer of O. If a is a fractional ideal of O, we denote by Na ∈ Q the norm of a. So if a ⊂ O is an ideal, we have Na = |O/a|. Let | · | : k → R≥0 be the normalized absolute value on k, i.e. for x ∈ k, we have


Person re-identification (ReID) is the problem of identifying pedestrian images among multiple non-overlapping cameras. Most of the researches are based on the front view or side view of the human body. However, there are many challenges, such as occlusion, posture changes. Therefore, based on top view images, we propose a person reidentification method, called ML-CM (multi-layer joint classification-metric deep learning). The proposed method uses classification models and integrates them into the Siamese network, which is the unification of classification and metric learning. It is more suitable for top view images. In this way, minimum intra-class variance and maximum inter-class variance are achieved. We have collected the top view images of 1008 people as TVPR (top view person re-identification) dataset and conducted experiments, demonstrating that the deep features obtained by our approach can get a competitive result.


A new series of heavy duty diesel engines has been designed, developed and launched into production. This has a bore x stroke of 175 x 220mm. The in-line 4, 6 and 8 cylinder direct injection (DI) 17 bar bmep engine covers the power range of 400-960hp for versatile applications such as generators, marine and locomotive propulsion. The optimum design of air flow and fuel flow, thermodynamic calculations for optimum performance, comparison with experimental data form a major part of this paper. The calculations of valve timings is explained in detail. The problem of secondary injection was solved by reducing the dead volumes.