Magnetic properties, phase constitution, and microstructure of melt spun R-lean and B-enriched Mischmetal (MM)–Fe–Co–Ti–B nanocomposites have been investigated. The thermal magnetic analysis show that only 2:14:1 and α-Fe [α-(Fe,Co)] phases appear for MM(A)9.5Fe78.5Ti2B10 and MM(A)9Fe79.5Co2.5Ti1B8 ribbons, while an additional Fe3B phase is present for R9.25Fe79.25Co2.5Ti1B8 [R=MM(A), MM(B), and MM(C)] ribbons. The magnetic properties of the above nanocomposites are determined not only by the phase constitution of MM–Fe–Co–Ti–B nanocomposites but also by the composition of MMs. Besides, fine grain size of 15–40 nm is almost unchanged for the ribbons with various MMs, giving rise to the strong exchange coupling effect between magnetic grains and the improved magnetic performance. In this study, the optimum magnetic properties of Br=9.6 kG, Hic=8.6 kOe, and (BH)max=18.2 MG Oe can be achieved for MM(B)9.25Fe79.25Co2.5Ti1B8 nanocomposites.


Title: Production analysis of capacity and design of production layout for EWP Windtower production – A paradigm changing comparative study from a holistic perspective to stretch the limitations whit in building new windtower factories. Authors: Konrad Ekenberg Advisors: (EWP): Coordinator of production Mahyar Mansoori Advisors: (EC): Lektor Christer Kedström


We propose a self-interacting inelastic dark matter (DM) scenario as a possible origin of the recently reported excess of electron recoil events by the XENON1T experiment. Two quasi-degenerate Majorana fermion DM interact within themselves via a light hidden sector massive gauge boson and with the standard model particles via gauge kinetic mixing. We also consider an additional long-lived singlet scalar which helps in realising correct dark matter relic abundance via a hybrid setup comprising of both freeze-in and freeze-out mechanisms. While being consistent with the required DM phenomenology along with sufficient self-interactions to address the small scale issues of cold dark matter, the model with GeV scale DM can explain the XENON1T excess via inelastic down scattering of heavier DM component into the lighter one. All these requirements leave a very tiny parameter space keeping the model very predictive for near future experiments.


Computer generated diffractive optical elements have been written in binary form in chrome on glass using the electron beam facilities at the Rutherford Appleton Laboratory in the UK. Some of the properties of polygonal elements are considered. These elements have been used as masters for subsequent copying into DCG to obtain higher diffraction efficiencies.


The evaluation of remote sensing imagery segmentation results plays an important role in further image analysis and decision-making. The search for the optimal segmentation method for a particular data set and the suitability of segmentation results for the use in satellite image classification are examples where the proper image segmentation quality assessment can affect the quality of the final result. There is no extensive research related to the assessment of the segmentation effectiveness of the images. The designed objective quality assessment metrics that can be used to assess the quality of the obtained segmentation results usually consider the subjective features of the human visual system (HVS). A novel approach is used in the article to estimate the effectiveness of satellite image segmentation by relating and determining the correlation between subjective and objective segmentation quality metrics.


In case of spices or crude drugs of medicinal- and aromatic plant origin, sensory characteristics, especially odour, has great commercial importance. The instrumental sensory analysis the so-called 'electronic nose' has proved to be a significant, new and quick method in chemometry. The sensor signal responses (data recorded by the electronic nose instrument) of the electronic nose were evaluated by statistical methods, including principal component analysis (PCA) and canonical discriminant analysis (CDA) and the combination of these methods by applying the discriminant analysis on the first eight principal components. The aim of this paper is the comparative analysis of the above evaluation methods as data processing tools of the sensor signal response of the electronic nose (chemosensor array). The essential oil of oregano (Origanum vulgare subsp. hirtum) selected line No. 10 was compared to the oil distilled from the selected line No. 11; and dried root samples of lovage (Levisticum officinale) harvested at different times from the two- and three-year-old population, were investigated with electronic nose (NST-3320, AppliedSensor Sweden AB). Principal component analysis, as a first step of the evaluation, did not clearly distinguish either oregano or lovage samples. Further statistical evaluation of the original sensor signal responses of the electronic nose with canonical discriminant analysis improved the separation power of the model. The best separation could be achieved by the combination of the two methods, whereby canonical discriminant analysis was applied to the first eight principal components, which described 99% of the differences. In all cases more than 92%, while in several experiments 100% of cross-validated grouped cases were classified correctly. Based on the results, the application of the electronic nose and the combination of multivariate methods, PCA and CDA, could be an appropriate tool either for identification of cultivar to accelerate selection process or to distinguish crude drugs of different age or different harvesting period.


Bioplastic or biodegradable plastic is one of alternative replacement to conventional plastic that has the potential to harmful to the environment. One of the raw material that has the potential to be made into bioplastic is sago starch because it has ability to degraded. The general purpose of this research is to determine the characteristics of sago-based bioplastic by modified the citric acid, microcrystalline cellulose filler, plasticizer sorbitol and glycerol. The synthesis method is casting of starch, water, filler Micro Cristalline Cellulose (MCC) with varying plasticizer sorbitol and glycerol with composition of filler is (15-25 % w/w), composition of plasticizer (25–
35 % w/w), and composition citric acid (3-9 % w/w). The results showed that the treatment with the addition of
MCC fillers, plasticizers, and citric acid are contributed to the mechanical properties produced. In the best process conditions (20% w/w MCC filler, plasticizer sorbitol 30% w/w with citric acid 0.95% w/w) give result Tensile strength 15.84 MPa, Elongation 9.32%, Young's Modulus 171.2 MPa, Biodegradation 51.65%, and wavelength absorption 1722.51 cm-1


The platform system of the present invention is one huge stereo overhead transport network for automatic cable cars to run in high speed and consists of modern turrets, towers and cable car lanes. Ithas cable cars as main carrier tools. As one basic installation for overhead city transport network, the present invention lays a practical technological and material foundation for the construction of overhead city transport network.


Indonesia has one of the largest wet seaweed producer in the World. It will impact the  economic value if the seaweed processing industry small and medium-scale can be established disentra seaweed production centers such as in Eastern Indonesia. The establishment of the seaweed industry small and medium-scale can be realized through several approaches, both economic and financial approach. The research method using descriptive analytic  with field surveys as reinforcement data analysis . The object of  this study is the financial analysis of the seaweed industry in Indonesia, especially in eastern regions such as South Sulawesi, Central Sulawesi, North Sulawesi, West Nusa Tenggara, East Nusa Tenggara, Maluku and North Maluku. The results of the financial analysis of the overall approach to demonstrate the positive zone seen from the feasibility, both NPV, IRR, and Payback Ratio ratio BC


The paper is devoted to the investigation of Shahbuz accents of the Azerbaijani language. The questions connected with the phonetics and morphology of the Shahbuz accents are investigated. It is determined that the syntactical differences show itself in the comparison with the literary language. The minority of these differences arise from the stability of the syntactic structure of the Azerbaijani language and its unity. The other reason is correct establishment of the Azerbaijani literary language on the basis of the national language. The author shows that there are few radical differences between the syntactic structure of the dialects and syntactic structure of the Azerbaijani literary language, but existing ones are not belong to one dialect and accent, belong either to dialect group or to the general dialects and accents of the Azerbaijani language. It is clear that Shahbuz accents are rich on both phonetic and grammatical aspects and is the product of long centuries. Here one can come across with many old words and expressions related to the growth way, life, welfare of the Azerbaijani language, these reflect the history of the Azerbaijani language. From this point of view, the study of the dialects and accents of the Azerbaijani language has a great significance. There are many similar and different aspects in relation with the literary language and other group of dialects or accents in Shahbuz accents.


Susan Bernofsky, Foreign Words: Translator-Authors in the Age of Goethe. Detroit: Wayne State UP, 2005.239 pp. Bernofsky's study, part of Wayne State's Kritik series, is not a broad-based study of translator-authors in the Goethezeit as the title suggests, but rather an in-depth study of the role translation plays in the works of Kleist, Holderlin and Goethe. As should be apparent from her focus on these three figures, Bernofsky is less interested in translators who happened also to be authors and more on canonical authors who also produced translations during their careers. Although the readings of individual works are insightful, the greatest contribution Bernofsky makes in her book is the dichotomy between service and authorial translations. Lawrence Venuti's concept of "foreignizing translation" as articulated in his The Translator's Invisibility underlies Bernofsky's distinction between types of translation. Whereas Venuti contrasted foreignizing and domesticating translations on the basis of the degree to which translators employ "cultural references and linguistic structures specific to the work being translated and its original language," Bernofsky postulates service translation as attempting "to emulate the characteristic features of the individual original work" (2, 3)- Both foreignizing and service translations attempt to preserve a high degree of fidelity with the original text. In contrast, authorial translation represents a writer's appropriation and "shaping of the translated text in a particular direction" (x). Bernofsky argues that this type of translation only became possible in light of the rise of service translation during the Age of Goethe. Bernofsky devotes her first chapter to this rise of service translation, best exemplified by Johann Heinrich Vofi's translations of Homer and August Wilhelm Schlegel's translations of Shakespeare. Although VoB and August Schlegel were authors in their own right, they are, as Bernofsky notes, best known for their translations. The converse, of course, is true with Kleist, Holderlin and Goethe, with the possible exception of Holderlin's Pindar translations. Thus, the emphasis on this generally overlooked aspect of the works of these three authors is worthwhile. Heinrich von Kleist's Amphitryon bears the subtitle Ein Lustspiel nach Moliere. Bernofsky's strongest pages are those in which she details how Kleist transforms Moliere's seventeenth-century comedy into "a tool to serve his [Kleist's] own aesthetic, literary, political, and philosophical ends" (48). …


Background: Nearly 93 million children worldwide live with disabilities. Disparities in activity participation between children and youth with and without disabilities increase with age, resulting in fewer opportunities for children and youth with disabilities to prepare for healthy independent living in adulthood. Parents often manage their youth's activity participation on their own or with limited intervention support while balancing competing demands on their time. Parents need practical tools to efficiency develop, manage, and communicate their efforts to promote children's participation. The Participation and Environment Measure for Children and Youth (PEM-CY) is a valid and reliable parent-report survey that enables detailed assessment of children's participation in home, school, and community environments. Providers and parents have expressed their interest in using mobile technology to actively and feasibly develop their own plan of care using the PEM-CY. Towards this end, we need to know how the PEM-CY can be used to support collaborative goal setting and plan management within a clinical intervention or self-management context.

Objective: To characterize a decisional support algorithm that enables parents of children with disabilities and their providers to leverage their PEM-CY baseline results in order to systematically and feasibly prioritize needs, formulate goals, and develop intervention strategies to promote youth activity participation.

Methods: We employed an explanatory sequential mixed methods (quan>QUAL) design. The quantitative (quan) phase included PEM-CY completion by 23 parents of children with disabilities ages 5-17 years who were actively enrolled in community recreation services in Northern Colorado. For the qualitative (QUAL) phase, 7 service providers participated in 60-minute interviews to provide their perspectives about how PEM-CY results could be applied within an intervention planning context. Interview data were content coded by two research staff using NVivo 10.0. We used established procedures to ensure credibility (triangulation of 3 data sources, member-checking (n=3), key informants (n=40)), dependability (two coders for first 5 transcripts), and transferability (confirming study results across cases that differed by child's age and gender).

Results: A majority of respondents were mothers (90.9%) and between 40-49 years old (72.7%). Most children (mean age = 10.7 years) were Caucasian (77.3%) and male (69.8%). Based on PEM-CY results, more than two-thirds of parents were dissatisfied with their child's participation in community events (73.9%), organized and unstructured physical activities (73.9%), unstructured physical activities (73.9%), getting together with others (69.6%), and classes or lessons (73.9%). Provider perspectives of PEM-CY case results yielded a decisional process with five decision-making processes that result in three major steps: 1) a rank ordering of activities in which change is desired is developed by parent, considering the child's interests, abilities, and/or family schedule; 2) provider clarifies parent's goals for their child's participation for each ranked activity, especially if there is mismatch between the type of change desired and child's current participation; and 3) provider probes to identify those environmental supports and parent strategies that can be leveraged and environmental barriers that can be minimized to promote participation.

Conclusion: Results suggest that a core decisional process for applying PEM-CY results to generate an activity-specific action plan is possible. Confirmation of this decisional support algorithm with the end-user (i.e., parent) is needed. In addition, parent feedback on core and optional features of mobile technology to support use of the decisional support algorithm would be useful to develop functional specifications and wireframe of the mobile app. []


the period in question. This shortage guided the author's choice of topic. She constructed this account primarily by comparing local, regional, and international media coverage of the events in question and by heavily supplementing this understanding with secondary-source citations. Although the author occasionally refers to anonymous oral testimony, the lack of accessible government documents or official memoirs makes it impossible to compare explicitly what was said in public with what was discussed in private. When such materials become available, it will be possible to add more depth and behind-the-scenes detail to the relationships described in this book. A quick flip through the book might give one the (false) impression that parts of the book are overly reliant on secondary sources or English-language analytical bulletins (MECS, MEI, MEED, etc.). However, the endnotes in the back of the book add a good deal of important information to the in-text citations. The bibliography as well as the extensive periodical citations in later sections demonstrates that the author consulted a wide variety of titles from the Arabic press. Sunayama does not overstate her argument by presenting sensitivity to Arab nationalist and Islamic identities as the sole determinant of relations. Instead she presents a nuanced, detailed narrative that tracks the relationship between the two states and highlights instances where she sees ideological concerns playing a crucial role.


For most adults an anthology of comic strips will arouse two chains of association. One has to do with nostalgia, the other with an awareness of changing cultural patterns. The two may intermingle. The degree of nostalgia will depend on one's age. Those whose memories readily extend back to the second decade of the century will, on seeing this new volume, scan it eagerly for the old favorites—the Katzenjammer Kids, Krazy Kat, Happy Hooligan, Jiggs and Maggie. All these and more are represented by at least a few samples that bring back old memories—in my own case, eg, spreading the newspaper on the floor (that was an important part of the ritual, perhaps because I was too small to hold the paper more properly) and reading the captions while lying prone. Each of us will have different memories and emotional reactions, depending, obviously, on the point in time when the


A variational coarse-graining framework for heterogeneous media is developed that allows for a seamless transition from the traditional static scenario to a arbitrary loading conditions, including inertia effects and body forces. The strategy is formulated in the spirit of computational homogenization methods (FE$^2$) and is based on the discrete version of Hill's averaging results recently derived by the authors. In particular, the traditional static multiscale scheme is proved here to be equivalent to a direct homogenization of the principle of minimum potential energy and to hold exactly under a finite element discretization. This perspective provides a unifying variational framework for the FE$^2$ method, in the static setting, with Dirichlet or Neumann boundary conditions on the representative volume element; and it directly manifests the approximate duality of the effective strain energy density obtained with these two types of boundary conditions in the sense of Legendre transformation. Its generalization to arbitrary loading conditions and material constitutive relations is then immediate through the incremental minimum formulation of the dynamic problem \`a la Radovitzky and Ortiz (1999), which, in the discrete setting, is in full analogy to the static problem. These theoretical developments are then translated into an efficient multiscale FE$^2$ computational strategy for the homogenization of a microscopic explicit dynamics scheme, with two noteworthy properties. Firstly, each time incremental problem can be solved exactly with a single Newton-Raphson iteration with a constant Hessian, regardless of the specific non-linearities or history-dependence of the micro-constituents' behavior. Secondly, the scheme concurrently solves for the microscopic and macroscopic degrees of freedom, in contrast to standard approaches based on sequential or nested minimizations.


Copyright: © 2014 de Souza ME, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Biofilms are high degree organization communities where microorganisms form a structured, coordinated and functional thin layer [1]. The biofilm production is a successful strategy for microbial survival and infection establishment. The host defense mechanisms and the antimicrobial responses are very impaired against the microorganisms inhabiting the biofilm [2]. This resistance may be related to the antimicrobial penetration difficulty by the cell wall composed (extracellular polymeric substances such as EPS). Such factor enables unlimited dissemination and expression of resistance genes with phenotypic changes of microorganisms in the biofilm [1]. In addition, microorganisms in the biofilm are mostly in their stationary phase, hindering the action of betalactam drugs.


In the composite food product combining the bakery foods and oily foods, and to provide an over time whitening bakery food portion for generating, fat and oil composition for bakery food capable of suppressing the bloom of oily food portions. Further, in a composite food product combining the bakery foods and oily foods, and to provide a composite food product whitening bakery food portion, the bloom of oily food portion is suppressed over time occurs. Fat composition of the present invention is characterized in satisfying that: (a) ~ (c). (A) C44~C48 triacylglycerol content of more than 20 wt% of the total triacylglycerols (b) the total content of SU2 triacylglycerol and U3 triacylglycerols in the total triacylglycerol is 40 mass% or less (c) unsaturated fatty acid content in all the constituent fatty acid is 18% by mass or more .BACKGROUND


In administrative, organizational, financial, and cultic duties, priests were often assisted and supported by cult attendants.

Keywords:

ancient Greece;
Greek history;
religious history


Mabuse's Danae (1527) is generally considered as a lower category erotic piece, but some have yet noticed its analogy with the Annunciation. After having underlined the connections between paganism and Christianism (their iconographies being often mingled, more particularly after the publication of the Corpus hermeticum by Ficino after 1463), this essay brings back the importance of the astrology in the religious believes and practices of princes and popes. The identification of the background buildings (Salomon's Temple and the edifices that come with it) authorises us to come to the conclusion that Danae and the Virgin Mary are identical, or even to reduce the latter to the former.


Hardware acceleration using FPGAs has shown orders of magnitude reduction in runtime of computationally-intensive applications in comparison to traditional stand-alone computers [1]. This is possible because on an FPGA many computations can be performed at the same time in a trulyparallel fashion. However, parallel computation at a hardware level requires a great deal of expertise, which limits the adoption of FPGA-based acceleration platforms. A recent interest to enable software programmers to use GPUs for general-purpose computing has spawned an interest in developing languages for this purpose. OpenCL is one such language that enables a programmer to specify parallelism at a high level and put together an application that can take advantage of low-level hardware acceleration. In this paper, we present a framework to support OpenCL compilation to FPGAs. We begin with two case studies that show how an OpenCL compilation could be done by hand to motivate our work. We discuss how these case studies influenced the inception of an OpenCL compiler for FPGAs. We then present the compilation flow and the results on a set of benchmarks that show the effectiveness of our automated compiler. We compare our work to prior art and show that using OpenCL as a system design language enables large scale design of high-performance computing applications.


To the editor:

We read with great interest the recently published article by Schultz and colleagues1 about the putative link between the expression of the zinc finger protein ZNA 804A and the cortical structure in schizophrenia and wish to comment from a "human neuroanatomical" perspective on selected aspects of this topic. A single-nucleotide polymorphism (SNP) rs1344706 in the intron of the zinc finger protein ZNF804A (rs1344706) is a replicated genetic risk variant associated with schizophrenia (reviewed in Hill and Bray2). In the endeavor to learn more about the role of ZNF804A in schizophrenia, Schultz et al1 performed a comprehensive allelic-specific gene expression study (homozygous risk allele AA carriers vs AC/CC carriers), combining magnetic resonance imaging cortical thickness and folding computing in genotyped patients with schizophrenia and healthy controls. Furthermore, they analyzed ZNF804A gene expression in a prefrontal region using postmortem tissue of schizophrenia patients and controls. It was revealed that in patients, AA carriers exhibited thicker cortex in prefrontal and temporal regions and less disturbed superior temporal cortical folding than AC/CC carriers, whereas the opposite effect was found in control cases. In addition, the expression analysis showed that the risk allele is associated with lower prefrontal ZNF804A expression in patients. This and other studies clearly imply that the expression of ZNF804A (and its gene variants) significantly impacts the developmental organization of human brain, both in health and disease. Indeed, the ZHF804A is thought to be prominently involved in brain development by influencing neural migration, neurite outgrowth, and the formation of synapses3 and was shown to be highly expressed in fetal (peaking in the second trimester) but not adult human brain.2 To better understand the role of ZNF804A in normal and disease-related brain development, it would be very important to know the regional and cellular expression of this protein in developing brain and adult human brain. Amazingly enough, this aspect has not been studied so far. We therefore immunohistochemically analyzed the expression patterns of ZNF804A protein in 4 adult human brains from psychically healthy individuals (3 males, 1 female; aged between 43 and 55 years) and 4 fetal brains (17th, 19th, 22nd, and preterm 28th gestational weeks). All brains were obtained from the Magdeburg brain collection.4 Case selection procedures, the acquisition of personal data, autopsies, and the handling of autoptic material were all conducted in strict accordance with the Declaration of Helsinki and were approved by the responsible Magdeburg Ethics Committee. In adult brains, we found a wide neuronal expression in the cortex (figure 1A), thalamus, hippocampus, hypothalamus, cerebellum (figure 1B), and brain stem. In mid-gestational brains, ZNF 804A was highly expressed in multiple neuroblasts and radial glial cells (figure 1C). Our findings strongly support, from a neuroanatomical viewpoint, the notion that ZNF804A might be an important player in neurodevelopmental processes.1–3 However, its relatively high expression in mature human brain neurons leads us to assume that ZNF804A is relevant for adult brain functioning as well. Especially the strong expression of this protein in normal cortical neurons (together with a proposed altered neuronal expression pattern in schizophrenia) might well contribute to differences in cortical thickness between schizophrenia and control brains as observed by Schultz et al1 and others. Whether or not the cellular expression patterns of ZNA804A is really altered in schizophrenia is currently completely unknown. We therefore are about to conduct an immunohistochemical study on ZNF804A localization in brains of schizophrenics and healthy controls with and without the SNP rs1344706 to learn more about the cellular consequences of this mutation.

Fig. 1.

Immunohistochemical demonstration of ZNF 804A in adult and developing human brain. (A) Temporal cortex of a 49 years old male. TNF 804A is expressed in layer III pyramidal cells and interneurons. (B) Cerebellum of a 55 years old female. A vast majority ...


Background and aim: About one-third of the world's population has some serologic evidence of suffering infection by hepatitis B virus (HBV). One of the effective measures for reducing the mortality because of hepatitis B virus is vaccination at birth time, 2 months and 4 months old. The criterion for effectiveness of hepatitis B vaccine is enough production of antibody. The aim of this study is to investigate the immunity response to hepatitis B vaccination in breast-fed and formula-fed infants vaccinated at the age of 12-24 months. Material and methods: This descriptive study is conducted using accessible sampling based on entrance criteria on healthy 12-24 months old infants who received 3 dose of hepatitis B vaccine. one group was 51 formula-fed infants and the other 56 breastfed infants. Blood sample was taken from both groups to measure the antibody titer of hepatitis B using ELISA experimental method, and finally both groups were compared based on their antibody level and age, sex and the type of feeding. Results: Both groups were the same with regard to age average and sex. Overall 9 infants (8.4%) had antibody titer of lower than 10 mIU/ml and didn't response well to vaccine, among whom 1 was breast- fed and 8 ones were formula-fed infants. HBS-Ab average was 124.4±55.9 mIU/ml and 91.7±51.1mIU/ml in the first and second group respectively (p=0.002).The response in the first group (98.2%) had a meaningful difference with the second group (84.3%) (p=0.009). In each group, there was no significant statistical difference between girls and boys in responding the vaccine, but in both groups overall, the boys had more immune response to hepatitis B vaccine compared to girls (p=0.004). Conclusion: The results of this study showed that breastfed infants respond well to hepatitis B vaccine and the average antibody titer is higher in boys. (Mohsenzadeh A, Ahmadipour SH , Firouzi M, Babaei Homa, Anbari KH. Effect of Breast-feeding and Formula- feeding on Antibody Response of Hepatitis B Vaccination. Life Sci J 2013;10(1):2063-2068) (ISSN:1097-8135). http://www.lifesciencesite.com . 293


In this paper we compare search and inference in graphical models through the new framework of AND/OR search spaces. Specifically, we compare Variable Elimination (VE) and memoryintensive AND/OR Search (AO) and place algorithms such as graph-based backjumping and no-good learning, as well as Recursive Conditioning [7] and Value Elimination[2] within the AND/OR search space.


eld to the single-q helical state in the chiral magnet, the skyrmions appear. The topology of the skyrmion is characterized by the skyrmion number Nsk dened as Nsk = ∫ d 2 r 4π n [(∂ n/∂x) (∂ n/∂y)], where is the unit vector along magnetic moment at r, assuming the two-dimensional conguration. The singleq helical state is a topologically trivial magnetic texture, i.e., Nsk = 0. Therefore, within the continuous deformation, there is no way to realize the skyrmions from the single-q helical state. We nd, by a numerical simulation of Landau-Lifshitz-Gilbert equation, the pair nucleation of skyrmion and anti-skyrmion occurs, and they annihilate to reach the skyrmion crystal-like state or the ferromagnetic state. We show the lives of skyrmion and anti-skyrmion in the dynamics of a quenched chiral magnet.


Boundaries may happen to develop along certain geographic features that eventually correspond to geothermally significant geological structures. In the case of the Ethiopia-Djibouti border, two active volcano-tectonic systems are extending on both the northern and southern side of the border: The Manda Inakir volcanic range to the north The Gobaad graben to the south, which include Lake Abhe and Dama Ale volcano. Manda Inakir volcanic range was shown by Haga et al. (2012) to be a site of potential geothermal interest, with a well-defined rift structure, as it is one of the active spreading segments in Afar, having encountered at least one historical eruption. The site is however rather remote and is not given a high priority on any side of the border at present. Nevertheless, the railway line project to link Dallol and Mekele to the port of Tadjourah, if engaged, would renew the interest for this potential geothermal site. The recent evolution of the diplomatic relations between Eritrea and Ethiopia may also change the game, as this is the nearest geothermal site to the port of Assab. More mature appears to be the Lake Abhé geothermal prospect, which was recognized long ago (BRGM, 1972) as a target of geothermal interest, due to the spectacular travertine chimneys found on the Eastern shore in the Djibouti Republic, which – besides being a touristic attraction, still draw the interest of geo-scientists (see f.i. Dekov et al. 2014). The site was reconsidered recently and taken as a priority target by the Office Djiboutien de Développement de l'Energie Géothermique (ODDEG) (Awaleh et al., 2015; Kaireh et al., 2016) and it benefitted from the support of ICEIDA in the frame of a project of ODDEG's capacity building. However, the geothermal conceptual model that can be deduced from the surface studies that have so far been done imply that the heat source of the geothermal system is located to the West; that is at the level of the Dama Ale volcano found on the Ethiopian shore of Lake Abhé. In fact, the Lake Abhé geothermal system is located on the Eastern extremity of the Tendaho-Gobaad graben, which bears several active volcanic units including Gabilema to the south. Both Gabilema and Dama Ale are located at the northern tip of the Main Ethiopian Rift at the place where it hits against the Red Sea – Gulf of Aden oceanic ridge crossing through Afar (Tazieff et al., 1972, Barberi & Varet, 1977, 1978). Their respective volcanic evolution shows magmatic series ranging from basalts to rhyolites, expressing the presence of magma chambers, i.e. shallow heat sources. Considering the location of the heat sources, and the hydrogeological context with surface and groundwater flow from West to East, a sound exploration programme of the area should rely upon a cross-border survey including both Ethiopian and Djiboutian partner organizations. A joint geothermal exploration project would enable the identification of the heat sources, the hydrogeological context and the nature and extension of the reservoirs – located in both sedimentary and stratoid series layers and bearing fluids of economic interest. It is not excluded that relevant financial agencies would be interested to support this kind of project, which would ultimately be of strategic interest for the sustainable development of the region.


This work expounds the review of non-destructive evaluation using near-field sensors and its application in environmental monitoring. Star array configuration of planar electromagnetic sensor is explained in this work for nitrate and sulphate detection in water. The experimental results show that the star array planar electromagnetic sensor was able to detect nitrate and sulphate at different concentrations. Artificial Neural Networks (ANN) is used to classify different levels of nitrate and sulphate contaminations in water sources. The star array planar electromagnetic sensors were subjected to different water samples contaminated by nitrate and sulphate. Classification using Wavelet Transform (WT) was applied to extract the output signals features. These features were fed to ANN consequently, for the classification of different levels of nitrate and sulphate concentration in water. The model is capable of distinguishing the concentration level in the presence of other types of contamination with a root mean square error (RMSE) of 0.0132 or 98.68% accuracy.


(54) SILVER SALT PHOTOTHERMOGRAPHIC (30) Foreign Application Priority Data DRY IMAGING MATERIAL AND PRODUCTION METHOD OF THE SAME Nov. 5, 2003 (JP).................................. JP2003-375349 Dec. 19, 2003 (JP).................................. JP2003-422484 (75) Inventors: Hiroaki Ando, Tokyo (JP); Kazuhito Ihara, Tokyo (JP); Shinichi Karakata, Publication Classification Tokyo (JP); Kazuyoshi Shioiri, Kyoto-shi (JP) (51) Int. Cl. ................................................... G03C 1/00 (52) U.S. Cl. .............................................................. 430/619 Correspondence Address: MUSERLIAN, LUCAS AND MERCANTI, LLP 475 PARKAVENUE SOUTH (57) ABSTRACT 15TH FLOOR EW YOR Y 10016 (US N K, N (US) A photothermographic imaging material containing a Sup (73) Assignee: Konica Minolta Medical & Graphic port having thereon photoSensitive Silver halide grains, Inc. 9 light-insensitive organic Silver Salt grains, a reducing agent for Silver ions and polymer, wherein and average particle (21) Appl. No.: 10/976,005 size of the photosensitive silver halide grains is 0.005 to 0.1 tim, and the polymer dissolves both in water and in an (22) Filed: Oct. 28, 2004 organic Solvent.


Based on the explication of structural and functional relations, a scientifically methodical approach to modeling the relationship between financial intermediaries' illegal activities, the trust crisis in the financial sector, and its deformations have been developed. Based on the construction and analysis of the relevant structural equations, it has been empirically confirmed that the probability of financial intermediaries' involvement in shadow transactions increases with the aggravation of the trust crisis in the financial sector. Using the tools of the structural equations modeling, a mediator analysis was performed, Received: April, 2020 1st Revision: June, 2020 Accepted: March, 2021 DOI: 10.14254/20718330.2021/14-1/12 Journal of International Studies S ci en ti fi c P a pe rs © Foundation of International Studies, 2021 © CSR, 2021 Maryna Brychko, Taras Savchenko, Tetiana Vasylieva, Paweł Piotrowski Illegal activities of financial intermediaries: A burden of trust crisis 173 the results of which confirmed the hypothesis that the financial sectors' trust crisis contributes to the degeneration of financial institutions and markets with regard to their depth, access, security and efficiency, which, accordingly, results in higher shadow transactions involving financial intermediaries.


In this paper I analyze why is important to consider the entrepreneurship as a key tool for the bank crisis. I related entrepreneurship with creativity, because both concepts are needed as you will see among its reading. The search investigation was based in a questionnaire to our students trying to discover their desire to become entrepreneurs and also I related the main characteristics of the entrepreneurship with the creativity ones. Why did I do that? Because, at the present moment, the banks need other kind of management, other styles and the young people, I mean, the future students could help to reach it.


The nature, as well as the deteriorations and distortions of our sense of touch are analyzed. Presented are programs for rejuvenating the sense of touch. The massage of appropriate acupoints includes a newly discovered cranial Circle of Release which facilitates the reduction of 10 different types of emotional «armoring»


.. Background: The Ankle brachial index (ABI) measurements are commonly used inscreening and management of Peripheral Vascular Disease. In recent studies, Ankle brachial index (ABI) is utilized as a predictor of future atherosclerotic vascular disease and all-cause mortality. Purpose: The purpose of this study was to investigate utility of pre and post peripheral vascular intervention ankle-brachial index (ABI) assessmentinpatientswith the chronic limb ischemia. Study Design: Quasi experimental study. Setting: National Institute of Cardio-Vascular Disease (NICVD), Karachi, Pakistan. Period: January 2013 to June 2014. Methodology: The study included 23 patients hospitalized. According to study inclusion/ exclusion criteria, patients of chronic limb ischemia on clinical ground and the vascular lesions of lower limb according toTrans-Atlantic Inter-Society Consensus (TASC scoreclassification II) were evaluated and recruited. The lesions were further classified into three types, Aortoilliac, Femoropopliteal andTibioperoneal. Ankle brachial index (ABI) was classified according to American Diabetic Association. The study was approved by the ethical committee of NICVD. Data was analyzed using SPSS 20. Inc. Results: The mean age of the enrolled patients was 57.86±6.56 years. Majority of the patients were male 18(78.3%). The commonly found peripheral lesion was femoropopliteal in 9(39%), TASC grade A was commonwith 8 (62%) of cases. ABI score done pre and post procedure showed a significant difference with a (p-value<0.05) and there was an improvement of ABI scores in all the lesions after peripheral vascular intervention. Conclusion: The study results concluded that there was animprovement in ABI score after intervention of peripheral vascular surgery for lower limb segment and recommended its utility for the assessment in Peripheral Vascular Disease intervention.


Spectral inaccuracies in binaural synthesis caused by factors such as non-individualised HRTFs and headphone compensation filters can induce colouration artifacts; changing the perception of an intended auditory event. Detection thresholds for induced colouration artifacts can be used to approximate colouration acuity. If the colouration acuity with binaurally synthesised sound sources is perceptually equivalent to that with real sound sources, the binaural synthesis system can be considered acceptable for evaluating colouration in synthesised environments. Perceptual colouration detection thresholds using both real and binaurally synthesised sound sources were measured and compared as an indicator of colouration acuity.


According to a survey [7] carried out by the research institute Fafo in 2016, attitudes among youth with immigrant background differ partially from those of the majority population. However, the general trend is that the gap between their own attitudes and the prevailing attitudes of the majority society is gradually diminishing, especially when compared to the general attitudes of the parents' country of origin. Most indicators showed that Norwegian minority youth's attitudes on equality issues are close to the prevailing ideals. Attitudes on homosexuality are far more conservative than those of the majority.


This Research Full Paper presents the effects of computing identity sub-constructs on the persistence of computer science students. Computer science (CS) is one of the fastest growing disciplines in the world and an emerging critical field for all students to obtain vital skills to be successful in the 21st century. Despite the growing importance of computer science, many university and college programs suffer from low student persistence rates. Disciplinary identity is a theoretical framework that refers to how students see themselves with respect to a discipline and is related to long-term membership in a disciplinary community. The theory has been effectively applied in Science, Technology, Engineering, and Mathematics (STEM) to understand students' success and persistence. This study examines the effects of performance/competence, recognition, interest and sense of belonging on the academic persistence of computer science students. A survey of approximately 1,640 computing students as part of a National Science Foundation (NSF) funded project was developed and administered at three metropolitan public institutions. Confirmatory Factor Analysis (CFA) was performed to validate the sub-constructs of identity for use in a computing identity model. Then, a structural equation model (SEM) was constructed as a snapshot of the structural relationships for describing and quantifying the impact of the identity sub-constructs on persistence. The results indicated that our model for CS aligns with prior research on disciplinary identity but also adds the importance of sense of belonging. In addition, the findings indicate that students' academic persistence is directly influenced by their interest. A better understanding of these factors may leverage insight into students' academic persistence in computer science/engineering programs as well as a meaningful lens of analysis for further curriculum and extracurricular activities.


Abstract A model of inertial oscillations that may occur with, and be modulated by, deformation frontogenesis is formulated. The deformation parameter is α ∼ 10−5 s−1 and the Coriolis parameter is f ∼ 10−4 s−1. This timescale separation, distinguished by the ratio α/f ∼ 10−1, provides the basis for application of a two-timescale analysis that separates the frontal evolution from the inertial frequency oscillations. To lowest order, the inertial oscillations do not influence frontogenesis, described by the classical Hoskins and Bretherton model. The frontal evolution, characterized by the alongfront geostrophic wind, does, however, provide an amplitude modulation of the inertial wind oscillation and of the temperature that also undergoes an oscillation at the inertial frequency. Parameter values are chosen to illustrate frontal contraction and translation characteristics that can distort the wind hodograph from circular motion. Ground-level temperature traces also exhibit unusual attributes, such as an ini...


Traditionally, technical requirements for loudspeakers used in electronics products which are for instance as TV sets and audio recorders are understood well by every one. Especially there are a lot of mature technical standards to guide so that it seems no doubts exist at all. But it becomes complicated these years in China because of market and R&D reasons. A lot of loudspeakers need to supply to different countries. Therefore it is possible for Chinese manufacturers to meet different standards and technical requirements from different customers. Some basic questions, which are sine wave listening, power matching between loudspeaker and amplifier and so on become doubtful from tradition. Also there is a trend to demand loudspeaker with some technical specification beyond physics limitation. The suppliers often meet dilemma because of management reason. The positive and scientific discussion for related issues based on some observing and thinking is promoted.


Modern intelligent personal assistants are comprehensible. Despite this, their speech still
sounds artificial, where the prosody of the speech seems to be one of the major
difficulties. Both companies and researchers in the subject strive for naturalness in
synthetic speech, but if this is something that is desirable has neither been demented nor
confirmed. The purpose of this study was to investigate the importance of intelligent
personal assistants' speech for the user experience and if it increases with more
naturalness. The intelligent personal assistant Siri was chosen to perform an experiment
with repeated measures design consisting of three levels: Siri's speech, natural speech
mimicking Siri's prosody and natural speech. The results revealed no statistically
significant difference between the three levels. Hence, no difference was found between
natural speech and Siri's speech regarding the user experience. The study was also not
able to confirm whether prosody has an impact on the user experience. Further statistical
analysis found that there was a statistically significant difference between the natural
speeches and Siri's speech as to how easy they were to understand, where Siri's speech
was significantly more difficult to understand. That a statistically significant difference
can be found in terms of understanding the intelligent assistants but not for the user
experience could be an interesting discovery, but requires further investigation.


A Pickett plot is a powerful graphical technique for petrophysical analysis of well logs, which was developed initially to represent Archie's equation visually. Pickett plots rely on pattern recognition on a log-log scale observable on a set of porosities and the corresponding true resistivities taken from well logs. The analyses of these plots have been used in the past, primarily for the determination of water saturation. However, throughout the past years, Pickett plots have been extended and modified for the evaluation of other reservoir parameters of interest, such as permeability, process/delivery speed, bulk volume water, and pore throat apertures.
 In some recent works, applications of the Pickett plot have been extended from representing only a snapshot on time to describing and explaining several millions of years of burial, compaction, maturation trajectories, and petroleum generation. The word 'petroleum' as used in this paper includes oil, gas, and natural gas liquids.
 In this study, the Pickett plot has been modified and extended to include geomechanical parameters such as Vp/Vs, Poisson's ratio, Young's modulus, Shear modulus, bulk modulus, friction angle and Unconfined Compressive Strength (UCS). A better understanding of these parameters helps to minimize risks associated with drilling, stimulation, and wellbore stability problems. Geomechanical characterization is vital to understand fracture creation and propagation. Hydraulic fractures are more likely to be generated in brittle zones with lower tensile strength, lesser Poison's ratio, and higher Young's modulus.
 Mechanical properties are usually measured in laboratory experiments such as Triaxial Compression Tests carried out on core samples. But cores are not always available for testing; therefore, the original contribution of this paper is the construction of a modified Pickett plot that can help to perform quick and reasonable evaluations of geomechanical properties while at the same time carrying out standard petrophysical analysis of petroleum reservoirs. This type of integrated petrophysical-geomechanical interpretation on a single plot is not currently available in the literature.


Nowadays, construction is one of the main sectors that produces waste and consume more materials and energy, so there is a growing need for alternative construction technologies that allow us to modify this situation. In this context, this paper presents the development of an innovative proposal for an industrialized outdoor enclosure. This solution is based on a constructive system with prefabricated insulated sandwich panels, produced on the basis of a new eco-efficient composite material, based on raw stabilized clay. In this way, it is possible, prioritize environmental issues to significantly reduce the environmental impact generated during the manufacture of the piece. The use in the construction of buildings material such as stabilized raw clay can be an alternative to achieve buildings of nearly zero energy consumption. They are known both from a thermal comfort and ability to regulate temperature and humidity, as well as being materials that contain much less embodied energy. This study is a comparative analysis of building systems, as well, as a serie of selected patent systems and copyrighted materials. On the other hand, it also analyzes their enforcement against the values established by the Spanish building code.


Abstract Lower Paleozoic rocks of New Zealand comprise two major assemblages each with their own distinct sedimentary tectonic, metamorphic and igneous history; they thus represent two distinct tectono-stratigraphic terranes. In Nelson-Westland, the western, or Buller, terrane consists of the Western Sedimentary Belt, together with Ordovician paragneiss at Charleston and in Victoria Range. The sedimentary sequence, ranging in age from basal to Upper Ordovician, comprises continentderived quartz-rich turbidites with black shales inferred to have been deposited in submarine fans and slope basins. The eastern, Takaka terrane (Central and Eastern Sedimentary Belts) is much more varied in lithofacies, composition and age (Cambrian to Silurian) and itself comprises several tectonic, probably thrust, slices. Volcanics, volcaniclastics, siliceous and calcareous siltstone, conglomerate and turbidites dominate the Cambrian part of the sequence and indicate proximity to a Cambrian island arc. The oldest sediments ar...


Leading Schools in Challenging Circumstances, we are informed, 'documents an exception' to 'the majority' of educational research, which 'has little or no influence on the lives of schools, student...


The project has aimed to develop a new kind of back assistive device to reduce the risk of low back problems, mainly focused to industries and workplaces where manual handling are frequently occurr ...


How can teacher educators provide relevant and important content in an educational environment that is rapidly evolving? TED.com is a website that provides content that meets these criteria in its ...


Current research on context information focuses on the use of new kinds of sensors and on the aggregation and interpretation of sensor data. Having a closer look at applications supporting emergency scenarios with context information several problems arise. Emergency activities are complex coordination tasks which involve a multitude of different roles and resources. The definition of emergency scenarios and the mapping of relevant context information is a time-consuming and error-prone task.
 This work discusses how a model-based approach can support the definition of emergency scenarios at an abstract level. The abstract representation (PIM, Platform Independent Model) of an activity is then transformed into a platform-specific model (PSM), which includes a collection of context sensors. We show that the use of a model-based approach simplifies the definition of complex context-sensitive applications, and how this increases the flexibility to use different sensor platforms in different emergency scenarios.


Objective
To evaluate the correlation between the prognosis and the early lactate clearance in patients with hemorrhagic hypovolemic shock.

Methods
Prospective observation and collecting the data of 92 patients with hemorrhagic hypovolemic shock. APACHE II score, the mortality and the lactate clearance after 6hours were measured. The patients were analyzed with respect to survival and nonsurvival, low lactate clearance and high lactate clearance.

Results
There was no statistical difference between the two groups in age, sex, APACHE II score and the baseline of lactate. The early lactate clearance in survival group was significantly more than that in the nonsurvival group, (29.8±15.2)% vs (9.8±9.1)%, P<0.01. The mortality was in high lactate clearance group significantly less than that in the low lactate group, 11.3% vs 42.9%, P<0.01.

Conclusion
The early lactate clearance is a good prognostic factor of hemorrhagic hypovolemic shock.

Key words:
Hypovolemic shock; Lactate clearance


When a patient presents with visual symptoms (e.g., jaw claudication, headache, visual symptoms), a diagnosis of giant cell arteritis (GCA) is obvious,


Twitter is a well-known micro-blogging website which allows millions of users to interact over different types of communities, topics, and tweeting trends. The big data being generated on Twitter daily, and its significant impact on social networking, has motivated the application of data mining (analysis) to extract useful information from tweets. In this paper, we analyze the impact of tweets in predicting the winner of the recent 2013 election held in Pakistan. We identify relevant Twitter users, pre-process their tweets, and construct predictive models for three representative political parties which were significantly tweeted, i.e., Pakistan Tehreek-e-Insaaf (PTI), Pakistan Muslim League Nawaz (PMLN), and Muttahida Qaumi Movement (MQM). The predictions for last four days before the elections showed that PTI will emerge as the election winner, which was actually won by PMLN. However, considering that PTI obtained landslide victory in one province and bagged several important seats across the country, we conclude that Twitter can have some type of a positive influence on the election result, although it cannot be considered representative of the overall voting population.


We report a facile method to synthesize single crystalline copper 7,7,8,8- tetracyanoquinodimethane (CuTCNQ) nanostructures using the chemical vapor deposition (CVD) method. It was revealed that, through simply adjusting the temperature-rising rate in CVD process, the CuTCNQ nanostructures were controllable in both the size and morphology. The single crystal of the CuTCNQ nanostructures was characterized by SEM, TEM, XRD, XPS, IR, etc. The field emission property of the CuTCNQ was studied and the result revealed that field emission property of CuTCNQ depends on its morphology.


often worked in poor indigenous communities lacking adequate resources, and who were often themselves indigenous and female. And Stephen notes that the Oaxaca uprising took place within a wider national political context of political protest, following an extremely close July 2006 presidential election marred by allegations of widespread fraud that left an incumbent party right-wing candidate declared the winner over a leftparty candidate and provoked months of protests. Women, especially indigenous women, were leading actors in the APPO movement, most dramatically in one of the most remarkable episodes of the uprising, ''The Women's Takeover of Media in Oaxaca'' (Chapter 6), which lasted for several months and involved the state radio and TV stations. They took action that male leaders could not fathom and provided the movement with an exponentially more visible platform to reach and hear back from the public. For the first time, the face and voice of the media came to better represent the population of the state, as indigenous women demanded to be recognized and included in decisionmaking. (Also interesting, Chapter Five details the role of community and indigenous radio more generally.) However, Stephen also shows that not all indigenous actors were in agreement with the movement (in Chapter Eight), as she details the violent conflict between rival indigenous organizations (some state-aligned) before and after the unsuccessful attempt in 2006 to establish an autonomous Triqui (indigenous group) municipality in a rural northern region of the state. In the same chapter she also examines the cross-border organizing among mainly indigenous Oaxacan migrants in Los Angeles to become aware of and generally support the 2006 movement. Stephen takes a broader view of the movement-uprising in presenting the perspectives of local businesspeople and merchants (Chapter Seven) as well as the work of young artists in the movement (Chapter Nine). She found a surprising diversity of opinion among the merchantbusiness class, with many quite critical of the governor and his corrupt administration as well as critical of the protests, though they understood some of the grievances. These privileged groups tried to promote dialogue and mediation between the conflicting parties, which largely failed but did create more independent political actors among their class. In contrast, one of the more visible legacies of the 2006 movement is the mainstream acceptance of the vibrant protest street art and other artistic expressions by a lively collection of young artist-activists around the broader 2006 movement, which came to be valued in privileged art circles locally, nationally, and even internationally. This is an extremely well-researched and fascinating case study of an important contemporary social movement in our neighboring country to whom we are closely tied economically and culturally. While highly detailed, the main points come through clearly. It deserves a very wide audience, especially among those who are interested in not only social movements but also gender, ethnic, racial, and class inequalities and human agency, as well as political sociology, ethnographic research methods, and even immigration and transnational communities, not to mention those interested in Mexico and public policy. Stephen has made an important addition to the literature on human agency among subordinated groups as well as Mexican politics. In addition to the book, she and colleagues have created a very impressive, bilingual, freely accessible web site (http://faceofoaxaca .uoregon.edu/introduction/) to make available a wealth of data from the project, which should be invaluable to interested students, activists, journalists, and scholars.


The performance of advanced VLSI systems is limited by the interconnection bandwidthinside/between chips rather than individual performance of transistors. The attenuation or deteriorationof signals, arises from physical phenomena in transmission lines, restricts the maximum frequencyat which the signal can transmit. This paper investigates coding techniques that can modifysignal spectrum suited to channel frequency response based on the concept of spectrum shaping ofsignals. We discuss three types of coding techniques for high-speed serial links to evaluate their performanceas well as the feasibility for realizing efficient data transmission.


At normal body temperature as well as during pyrogen-induced fever, injections of 5-HT into the 3rd brain ventricle were found to cause peripheral vasodilatation, polypnea and a marked fall in brain, blood (right heart) and rectal temperature in 2 out of 3 goats. In the 3rd goat, which later developed encephalitis, 5-HT caused a short initial period of peripheral vasodilatation, followed by a syndrome, having all the characteristics of pyrogen-induced fever. Injections of small amount of catecholamines into the 3rd brain ventricle did not alter significantly the rectal temperature of the goats. The findings are discussed in relation to a recent hypothesis according to which body temperature is the outcome of a fine balance in the release of catecholamines and of 5-HT in the hypothalamus.


Abstract:This essay claims with Plato that learning to see and to love the beautiful is the fundamental impulse underlying education, leading to self-transformation. In Plato's educational theory, we discover the intimate connection between beauty, creativity, and art--a connection that today's education fails to emphasize, leaving us with the idea of creativity as mechanical or dull, if not totally irrelevant, and with art as marginalized--a discovery that is a journey of the self, or soul, into the world of transcendent beauty made visible in art as integrity, harmony, and radiance. Through these qualities, art can release us from our everyday experiences, so that we become an expression of something that is not of ourselves accompanied by a revelation that no words can describe but which can be expressed in the state of attentive silence, of looking, or of seeing. Therefore, this article advances a pedagogy of seeing or of looking or of attentive silence that can illumine one's way to what Plato calls "that place which is a rest from the road . . . for the one who reaches it."


The authors report the production of regular zincite nanospheres () in a single step, at room temperature using the macrocycle cucurbit[7]uril (CB[7]) as a clipping template in very small amounts. This procedure is the simplest way to obtain this semiconductor in such form and dimension directly from aqueous solutions of Zn(NO3)2.


Despite the relative success of poverty alleviation over the last two decades, the issue of social safety nets remains an intriguing issue in the area of the strategic intervention of the government of Bangladesh. This article aims at exploring two sets of challenges: adverse political incentives and obstinate behavioural norms. In doing so, the current article proposes a conceptual framework that highlights the effects of clientelism, institutional frameworks and their enforcements, and social, human and technological factors on social safety nets. Further, it also shows how social safety nets influence the reduction of poverty, vulnerabilities and risks, leading towards the capacity building and empowerment of vulnerable people. The case of Bangladesh is discussed in the light of the proposed conceptual framework. Points for practitioners State decision-makers and implementers may take cognizance of the importance of the participation of pro-poor civic forums at different stages of social safety net intervention, the allocation of adequate resources, and addressing numerous management deficits confronting social safety nets. International development organizations also need to consider the contextual variables while providing assistance to developing countries in general and Bangladesh in particular. Political actors and administrators also need to take into account major contradictions in the formulation and implementation of social safety net programmes in Bangladesh.


A b s t r a c t . Marta Torz, 50 de ani fără Dumnezeu: Apocalipsa si apocriful in "Un singur cer deasupra lor" al Ruxandrei Cesereanu [50 years without God: Apocalypse and apocrypha in Un singur cer deasupra lor by Ruxandra Cesereanu], Studia Romanica Posnaniensia, Adam Mickiewicz University Press, Poznan, vol. XLI/2: 2014, pp. 115-123. ISBN 978-83-232-2703-8. ISSN 0137-2475. eISSN 2084-4158. DOI: 10.7169/strop2014.412.010 This paper proposes the reading of Ruxandra Ceseranu's novel Un singur cer deasupra lor as a modern apocrypha presenting a historiosophic vision of Romania's fate in the second half of the 20th century with the use of apocalyptic themes and symbolic imagery. The analysis consists of tracing references to the Book of Revelation which is a key element to the interpretation of the novel, and to other biblical books and themes. The analysis is supplemented with an attempt at describing the most significant archetypical and cultural symbols, and the remnants of bygone traditions that provide the second reading to those historically-grounded stories. References to folk tales based on Christian imaginary world further strengthen the proposition of the apocryphal nature of the work. The additional argument supporting my thesis is the polyphonic and multilayer structure of the novel that combines subjective visions and mythical interpretations with the factual layer, and the use of palimpsest technique consisting of interweaving texts of other authors into the main narration. The paper does not address the question of the conformity of the literary vision with the source documents and historical prototypes of certain episodes and persons. Those matters were partly commented on by the author in the afterword. K e y w o r d s : Apocalypse, apocrypha, archetype, communism, symbol, totalitarianism


Abstract : This exploratory study investigates how writers represent their task to themselves before beginning to write. Using data from verbal protocols, we examine the initial plans of twelve writers (five experts and seven student writers) who were working on an expository writing task. The protocols were coded for types of planning. We also obtained independent measures of the quality of the subjects' plans and of the quality of their texts. The analysis suggests that both the quantity and quality of a writer's initial planning may make a difference in the quality of the final text. We found a positive correlation between the amount of initial planning and text quality, and between the quality of planning and text quality. In particular, we found that writers who developed rhetorical plans (i.e., plans for audience and purpose) tended to produce higher-rated texts. From our analysis, we hypothesize that experienced writers build a rhetorical representation of their task. We defined a rhetorical representation as one which is rich in rhetorical goals and plans relating to the audience, purpose, form and language of the text, and in which the writer integrates his plans to form a coherent theory of the task.


In order to explore the effect of organic manure on the dissolution of carbonate rock,the tilled and untilled soil layers were collected in the carbonate mountain area from Guiyang,China.Two columns were designed to perform the experiments.One column was filled with untilled soil layer(red clay) in the upper part and alkaline carbonate erosion residual in the lower part.The other was filled with tilled soil in the upper part and red clay in the lower part.The soil was fertilized quantitatively in accordance with local fertilization method and regular observations were made on the corrosion of carbonate rock slices buried in different soil depths and index variation of the water in the soil layers.Results showed that organic manure application in the untilled red clay can significantly lessen the carbonate rock corrosion and the lessening became weaker with the soil deepening,while it can bring slight corrosion increase for the underlying alkaline carbonate erosion residual.For the tilled soil layer,the organic manure application had no obvious influence on the carbonate rock corrosion and the corrosion slightly increases as the soil layer went deeper.The carbonate rock corrosion in the lower red clay was much heavier than that in the tilled soil layer,which suffered little influence of the manure application.Overall,the organic manure application can pose great influence on the carbonate rock corrosion in the untilled soil layer,but had minor influence on the rock corrosion in the middle and lower parts of the underlying alkaline carbonate erosion residual,and similarly the manure application bore little influence on the carbonate rock corrosion in the middle and lower parts of the tilled soil layer.The prohibition on reclaiming thin soil layers can positively alleviate the corrosion effect of organic manure application on the carbonate rock and effectively reduce the impacts of de-stony desertification,which will enrich the carbonate rock soil formation theory and provide scientific basis for the prevention treatment of desertification disasters.


representative GC-runs, fig. 3 the complete specific results for archaeal lipids. Figure 4 shows results from GDGT analysis, in particular the ring distribution of numbers and a phylogenetic tree of important community members. The concentrations and isotopic compositions of specific compounds as well as (relative) number of 16S sequences are presented in the supplements, although they are by far more interesting than exemplary GC runs. Hence these data should be displayed in the main text. Most results from the supplementary table and Supplementary Figure 1 are essential to the study – they show that sulfate methane transition zones are in the upper 20 to 50 cm. Somehow this is not further discussed in the manuscript – although this is core to the biogeochemistry.


Optimal development of the gastrointestinal tract (GIT) is essential in young birds for future growth and is related to immune function. The yolk, containing antibodies and good fatty acids, is the colostrum for the chick. In newly hatched chicks, the yolk accounts for 16% of the body weight, which is absorbed during the first 2-3 days. In commercial broiler operations it is not uncommon for newborn chicks to experience a delayed access to feed. With feed absence, the chick goes into survival mode and burns not only protein and fatty acids in the yolk, but also its own fat and muscle reserves from the organs, such as the liver and the heart. The digestive system of the bird at hatch has limited ability to digest and absorb nutrients. It is therefore vital to provide a diet that contains highly digestible and available nutrients. The metabolisable energy and amino acid digestibility of grains are lower in young birds and indigestible nutrients can serve as substrate for undesirable gut microorganisms. The aim should be to kick start the digestive system of the young chick as soon as possible. Feed particle size and feed presentation will play a significant role in this.


The second of three planned versions of the COPERNIC fuel performance code is nearing completion. The COPERNIC code development effort was launched in 1992 as part of a larger Framatome effort to develop a new generation of fuel-management codes. The COPERNIC code was developed primarily to produce accurate steady-state and transient extended-burnup fuel performance predictions and incorporate advanced materials. The COPERNIC code predictions are applicable to UO{sub 2}, UO{sub 2}-Gd{sub 2}O{sub 3}, and mixed-oxide fuel types. The first version of the code, which was completed in 1995 and is currently being licensed in France, was extensively benchmarked to moderately high burnups. The second version contains several improved models and is also being benchmarked to moderately high burnups. The third version will be benchmarked to very high burnups. Model highlights and measured-to-predicted data comparisons for the second version are presented in this paper.


Karaoke machines have become a popular choice for many people's daily entertainment. In this paper, we address a novel task of recommending a suitable key for a user to sing a given song to meet his or her vocal competence, by proposing the Personalized Competence-based Rating Prediction (PCRP) model. Specifically, we learn the song embedding vectors from the sequences of songs' notes, and then design a history encoder with recurrent units to extract users' vocal information from the history rating records and utilize a rating decoder based on the Transformer. The experimental results on a real world karaoke rating dataset demonstrate the effectiveness of the proposed approach.


Impediments, such as a lack of adequately trained human resources and institutional arrangements, must be overcome in order to utilize science and technology to optimize marine resource development opportunities. All too often, technology is viewed as a solution to a problem when in fact technology should be appreciated as a tool for revealing issues that may have escaped attention. A view of introducing only technology as a solution for national development problems is bound to fail without simultaneously introducing an appropriately integrated package of acceptable policies and institutional analysis. Therefore, the question that should be asked is not what appropriate technology can be identified to address national needs, but what appropriate institutional arrangements are required to optimize the opportunity for appropriate technology to succeed.


A simple synthetic route has been developed to obtain a new axially chiral, C2-symmetric, modified BINOL with the introduction of methyl substituted furan ring fused to the BINOL 1 framework. The successful placement of the furan moiety at C-7; C-8 and C-7�; C-8� positions of 1 resulted in the sterically demanding BINOL derivative. The synthesis of both enantiomers of methylsubstituted furo-fused BINOL has been carried out with high enantioselectivities


This paper, and its companion, investigate the evolution of dense stellar systems due to the influence of two-body gravitational encounters, physical collisions and stellar evolution. Our goal is the simulation of the densest centers of galaxies, like M32, which reach stellar densities near a million solar masses per cubic parsec and which may harbor black holes. These systems have a different Safronov number (the dimensionless ratio of stellar binding energy to mean stellar kinetic energy) than globular clusters, substantially increasing the importance of physical collisions relative to gravitational encounters. In this paper, we focus only on the gravitational encounters. We demonstrate, first, that our simulations with small N with a Hernquist tree code yield results basically in accord with years of effort studying globular clusters. Second, we investigate (crudely) core collapse in rotating systems with mass segregation, to separate out the effects purely due to two-body encounters from those seen in the more complex second paper.
Consistent with previous studies, we find that systems whose constituent particles follow the Salpeter initial mass function rapidly undergo core collapse through Spitzer's mass segregation instability. All rotationally flattened systems show a decrease in flattening with time, consistent with Fokker-Planck calculations. An interesting new result concerns the well-established inability of simulators to identify a static center in their simulations of collisional systems. We find that the lump of high mass stars which condenses at the center wanders about the core in Brownian motion.


The infra‐red absorption spectrum from 2 to 14.5μ was determined for cyclohexane vapor. The number of bands found in the 700–1350 cm−1 region confirms the chair structure (symmetry D3d) as the most stable at room temperature. The band envelopes are discussed and compare well with the theory of Gerhard and Dennison.


The invention discloses a rotary kiln heavy gear ring repairing method, and relates to a rotary kiln repairing method which is used in metallurgy, building materials and chemical industries. The method is characterized in that a repairing operation process comprises the following steps that: (1) a spring board and heavy gear ring connecting lug is cut off, and a heavy gear ring is removed; (2) the heavy gear ring is cleaned and set the heavy gear ring round; (3) the turned over heavy gear ring is hoisted and aligned; and (4) a pin shaft is installed, and a spring board and a new lug are welded. The rotary kiln heavy gear ring repairing method turns over and repairs the heavy gear ring under the circumstance of not replacing a tube section and the spring board, first cuts the spring board and heavy gear ring connecting lug, keeps a tube body and the original spring board unchanged, removes the gear ring and turns over the same and then replaces the new lug and the pin shaft; and after the heavy gear ring is aligned, the new lug and the original spring board are welded firmly. The rotary kiln heavy gear ring repairing method effectively saves the cost for the tube section, the spring board, a rivet and other spare parts, omits spring board installation, hole drilling, riveting and other procedures, and saves a certain repairing time.


FOR more than four decades the construction of a general location theory has been a stimulating challenge to spatial theorists. Despite the productive efforts of Weber, Englander, Predohl, Ohlin, Palander, Hoover, Losch, and others, the goals of spinning a theoretical web and specifying the design of a corresponding operational model are still remote.2 However, the comparatively recent pioneering contributions of Leontief in developing input-output techniques for general equilibrium analysis are of consequence here. They permit an attack upon a specific set of significant problems which logically fall within the jurisdiction of a general theory of location and space-economy. The analysis of changing interregional economic bonds and flows can be approached from several directions. The input-output method as elaborated here implicitly assumes, for the most part, unchanging spatial relations between any producer and his suppliers. Only a limited amount of industrial relocation can be tolerated with any change in the basic parameters of the economic system at any given point of time. An alternative approach has been sketched for example in an unpublished memorandum by Koopmans.3 Such an approach would treat the space factor explicitly. It would permit major variation in the spatial extent of production for each firm and in the geographic pattern of production and resource utilization. It would be consistent with major relocation of industry and population. It would reveal how distance actively conditions interregional economic relations.4 An operational model following this alternative, more desirable, approach is yet to be developed. This paper is concerned with the much more limited assignment of regional and interregional analysis within the rigid spatial framework necessitated by the postulates of input-output analysis.5 'The analysis in this article has greatly benefited from discussions with Guy Freutel and with Wassily W. Leontief, James S. Duesenberry, Leon Moses, and other members of the Harvard Economic Research project. However, the shortcomings of the analysis and the views expressed herein are the author's only. The model to be developed through spatial aggregation is basically different from one constructed by Professor Leontief through national disaggregation (in his forthcoming Studies in the Structure of the American Economy, Chapter 4). Nevertheless, the two models should not be viewed as alternatives. Rather they are complements. The Leontief balanced regional model is particularly useful for determining regional implications of national projections; the pure interregional model, for determining national implications of regional projections. (For elaboration of this point, see W. Isard and G. Freutel, Regional and National Product Projections and Their Interrelations, sections 7 and 8, paper prepared for Conference on Research in Income and Wealth, National Bureau of Economic Research, May 195I,) Since one can proceed by degrees from one type of model to the other, it is likely that after considerable experimentation an hybrid model, involving elements of both, may prove to have the most general utility. The author's experience in directing the preparation and collection of the data and in carrying through the computations for the Leontief model has been of great value in setting up a feasible design for his own model. 'For a presentation and evaluation of these efforts see W. Isard, "The General Theory of Location and SpaceEconomy," Quarterly Journal of Economics, Vol. 63 (November I949), pp. 476-506. 3T. Koopmans, The Optimum Geographical Distribution of Population and Industry in the United States (Cowles Commission for Research in Economics, January I946). 'Though trade theory is basically concerned with geographic flows, it has by and large ignored or set aside the space factor. This is in line with the economic theorist's customary preoccupation with the time factor. ;;Treating space implicitly or as a passive factor has also been characteristic of the better regional development studies. Colin Clark in his excellent works on economic progress in the various regions and nations of the world (The Conditions of Economic Progress, London, I940, and The Economics of I960, London, I942) does not attempt at all to study the basic changes in the spatial interrelations and patterns of these nations or regions. Nor does he probe into the diverse spatial structures of nations and regions at a given point of time. To be sure, he makes spatial comparisons in the sense that he compares nations having different latitudinal and longitudinal positions. But such comparisons more accurately fall under the heading of geographic description, not spatial analysis. A. J. Brown (Industrialization and Trade, London, I943, and Applied Economics, London, I947), in ascribing a significant role to the world's uneven pattern of resources and its implications for geographic specialization and the global locational structure of industry, takes a major step forw7ard. But he does not transcend "geographic positional" analysis. He does not expose the fundamental spatial scaffolding of international relations. Nor do E. F. Staley (Woorld Economic Development, Montreal, I944), the


A MEMS electro-thermal microgripper has been designed and discussed in this paper. The electro thermally actuated gripper consists of "hot-and-cold-arm" actuators. The micro-grippers are used to maneuver small delicate objects with nanometer scale precision and accuracy. Design parameters strongly influencing the performance of the gripper such as length of the hot arm, length and shape of the cold arm has been considered in order to optimize the performance. The gripper has a thickness of 25m. Simulation of the device has been done using the COMSOL Multiphysics software.


This paper presents the results obtained from the life cycle assessment of a paperboard box produced from virgin pulp and old corrugated box in Thailand. All materials and resources use, energy use, and emissions to environment of each processes in the life cycle were identified and analysed. In impact assessment, contributions to five environmental impact potentials were analysed i.e. global warming, acidification, eutrophication, photochemical ozone formation (smog formation), and solid waste generation. The result showed that the most important process with respect to environmental impacts was landfilling of the corrugated box after use. For energy use, drying processes in paperboard factory were the major contribution. For solid waste generation, board and box production was the major sources. A number of modifications in the product's life cycle were analysed in order to identify more environmentally friendly solutions. Emissions from landfill could be reduced significantly by increasing recycling and implementing efficient landfill gas collection and treatment system in landfills in Thailand. Reduction of electricity consumption in factories, re-design of the container for lower weight and increased reuse reduced impacts significantly throughout the life cycle.


Production of mother's milk by several factors one of which is consuming "jamu gejah". There can partitution mothers consume and do not consume "jamu gejah". 30 respondent ( 100% ). Based on preliminary study obtained 7 respondent (100%) who consume jamu gejah the production of mother's milk is smoothly. The purpose of the research to analyze different in the pattern of production quantity of Breast milk on parturition period between mothers who consume and do not consume jamu gejah at Sumber Suko Village and Wonosari field work UPT Health Center Kepulungan, Subdistrict Gempol, Pasuruan regency year 2017. Method of the reserchers is analitic. Design of observational research is where the researchers do direct observation. Independent variable consumption of jamu gejah by the mother of a dependent variable how can the production of breast milk. Design of observational research is where the researchers do direct observation. Population 30 respondent, sample 30 respondent parturition period taken using purposive sampling technique. Method of data collection in the form of observation sheet and the analyzed with a Wilocoxon mann-Whitney Test with a significance level of α= 0,05. Based on the results obtained, the volume of milk production between Breast Milk production volume that consumes an average production of breast milk was 242.2 cc and does not consume jamu gejah average production of breast milk was 178.2 cc has a difference of 64 cc. The test results of the statistic Wilcoxon mann-whitney test retrieved values ρ = 0.000 which means smaller than α so that 0.05 ha are received. So, there is a difference of jamu gejah against the production of Breast Milk during parturition. This research is expected to a childbirth mother her little Breast Milk production could consume jamu gejah, because with the results of the above research gejah herbal medicine consumption affects the smooth production of breast milk.


Data on sterilization with the Filshie Clip and its comparison with Pomeroys technique in India is presented. 147 patients are included--70 with Filshie Clips and 70 by the modified Pomeroy method. 30 had sterilization concurrent to hysterotomy and 40 underwent postpartum sterilization. Patients were followed up at 2 weeks 2 months 6 months and 1 year. The time taken for hysterotomy ligation and postpartum sterilization is shown. Difference was not statistically significant. Postoperative complications include fever wound infection and abdominal pain needing analgesics. 2 failures were encountered with the Filshie Clip technique; none by the Pomeroy method. The 1st failure occurred 6 months after application of the Clip in a hysterotomy ligation patient; the second 10 months after the application of Filshie Clip mark-3 in a hysterotomy patient. The Clip is quick and simple. Postoperative complications should be minimal as the tube is not cut. 10 failures have been reported with Filshie Clips so far. 8 failures with mark-1; 2 with mark-2; none with mark-3 or mark-4. In the present study 2 failures have been encountered 1 with a Filshie Clip mark-3 and the other with Filshie Clip mark-4.


We use recent theoretical advances to develop a functional form for interatomic forces in bulk silicon. The theoretical results underlying the model include an analysis of elastic properties for the diamond and graphitic structures and inversions of {ital ab initio} cohesive energy curves. The interaction model includes two-body and three-body terms which depend on the local atomic environment through an effective coordination number. This formulation is able to capture successfully (i) the energetics and elastic properties of the ground-state diamond lattice, (ii) the covalent rehybridization of undercoordinated atoms, and (iii) a smooth transition to metallic bonding for overcoordinated atoms. Because the essential features of chemical bonding in the bulk are built into the functional form, this model promises to be useful for describing interatomic forces in silicon bulk phases and defects. Although this functional form is remarkably realistic by the usual standards, it contains a small number of fitting parameters and requires computational effort comparable to the most efficient existing models. In a companion paper, a complete parametrization of the model is given, and excellent performance for condensed phases and bulk defects is demonstrated. {copyright} {ital 1997} {ital The American Physical Society}


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s for the Sixth Biennial SIRS Conference S98 Oral Session: Outcome Discussion: This analysis of real-world data found a sizable number of patients with dual diagnoses of schizophrenia and BD-I. Among all patients with either BD-I, schizophrenia, or both, about 2/3 as many met the criteria for both disorders as for schizophrenia alone. Fifteen percent of patients who met criteria for both did so on the same day, likely reflecting patients presenting to acute care exhibiting mixed features. A  review of medical records would be useful to determine if dual diagnosis is more common than suspected, and claims data should be examined to determine if these patients differ sufficiently from those with a single diagnosis to warrant exclusion from single-disease cohorts. O8.6. THE RELATIONSHIP BETWEEN COGNITION AND FUNCTIONAL IMPROVEMENT IN THE CONTEXT OF A PSYCHOSOCIAL INTERVENTION TARGETING SOCIAL DISABILITY IN FIRST EPISODE PSYCHOSIS Sian Griffiths*,1, Stephen Wood2, Renate Reniers1, Max Birchwood3 1University of Birmingham; 2Orygen, the National Centre of Excellence in Youth Mental Health; 3Warwick Background: Whilst Early Intervention Services (EIS) are the 'gold standard' treatment for young people with psychosis, in a recent study of over 1000 First Episode Psychosis (FEP) cases, 66% of individuals were experiencing a high level of poor functioning, despite receiving care under EIS for a period of 12 months (Hodgekins et al., 2015). This highlights the need to develop new interventions to target functional impairments in FEP. A specialised Social Recovery Cognitive Behavioural Therapy (SRCBT) has been developed which aims to address the underlying factors impeding social recovery, and has shown to be effective at improving structured activity in individuals with established illness and FEP (Fowler et al., 2013). Identifying the factors that contribute to functional change will ensure that targeted psychosocial therapies are being delivered appropriately. Impaired social cognition (SC) and neurocognition (NC) are closely related to poor functioning in psychosis. Exploration of SC and NC preand post-intervention will therefore be important to test underlying mechanisms of functional change, and identify individuals who are more likely to benefit from the specialized SRCBT. Methods: This study ran alongside a multi-site proof of concept trial of SRCBT, for individuals with FEP experiencing social disability. Participants (M age = 25 years) had less than 30 hours a week of structured activity before entering the trial. At baseline, 123 participants completed a battery of SC and NC assessments. 59 participants were randomly allocated to the therapy group (SRCBT + EIS), and 64 were randomly allocated to the standard care group (care from an EIS alone). Participants completed a follow-up assessment at 9 months on the same cognitive battery, and a further assessment of their structured activity. The assessors were blind to group allocation. A  small sub-sample of participants (N=6) allocated to the SRCBT group underwent functional magnetic resonance imaging (fMRI) scanning preand postSRCBT, to explore any changes in the social brain regions following successful intervention. Results: Regression analyses showed that SC was a significant predictor of treatment response (i.e. improved structured activity). Specifically, those who had better social knowledge at baseline were most likely to benefit from the SRCBT (Wald χ2 = 4.073; p = .044), accounting for 16% of the overall variance. To further illustrate this, individuals scoring in the top quartile for social knowledge achieved an additional 11 hours on average of structured activity post-intervention. Furthermore, in the group that underwent fMRI scanning preand post intervention, there were increased activations in the social brain regions, namely the temporo-parietal junction (TPJ), which became more refined and localized by follow-up. There was also a trend for increased signal intensity in the TPJ, with increased structured activity post-SRCBT. Although this was not significant (r = .455; p = .365), there was a moderate strength relationship Discussion: No studies to-date have examined predictors of treatment response to a CBT intervention targeting functional impairment in FEP. These findings have implications for practice where remediation of SC may improve the efficacy of the SRCBT, particularly for individuals who have poorer social knowledge. This study is also the first to provide preliminary insights into a functional brain network associated with improved structured activity in psychosis; however, replication of these findings in a larger sample is needed. O8.7. COGNITIVE SUBTYPES IN FIRST-EPISODE PSYCHOSIS AND ASSOCIATION TO TREATMENT RESPONSE Manuela Russo*,1, Simone Ciufolini1, Olesya Ajnakina1, Tiago Reis Marques1, Avi Reichenberg2, Anthony David1, Marta Di Forti1, Carmine Pariante1, Robin Murray1, Paola Dazzan1 1Institute of Psychiatry, Psychology and Neuroscience, King's College London; 2Icahn School of Medicine at Mount Sinai Background: Psychotic disorders are characterized by large heterogeneity in clinical presentation, response to treatment and cognitive functioning. Indeed, there is evidence of the presence of cognitive subgroups of patients across affective and non-affective psychosis. However, very little is known about these subgroups in first episode psychosis (FEP) and whether they can be informative about course of illness, particularly response to treatment. The aim of this study is to investigate the number and the pattern of cognitive clusters in FEP, their external validity and association with treatment response at 12-week and 1-year follow up. Methods: The sample was composed by a total of 212 participants including 105 FEP patients from the South London and Maudsley Foundation Trust and 107 Healthy Controls (HC). All participants underwent a comprehensive clinical and neurocognitive battery. Z-score [mean=0, and standard deviation (SD)=1] were created for the whole sample based on the neurocognitive performance of the HCs. Treatment response at 12-week and 1-year follow-up was used to explore potential utility of subtypes in predicting response to treatment. Hierarchical cluster analysis was carried out to determine the number of cognitive clusters in FEP patients. A series of analyses of variance were carried out to determine if FEP clusters differed among each other in relation to demographic and clinical characteristics, level of functioning and from the HC sample in term of cognitive performance. Logistic regression was used to explore whether cognitive clustering was predictive of treatment response at 12-week and 1-year FU. Results: Four cognitive clusters emerged: one with near normal cognition (42.9% of the FEP patients) with a general cognitive score of z=-0.20, one with selected cognitive deficits (14.3%) in the domains of verbal memory, processing speed and executive functions (general cognitive score of z=-0.55); and two severe deficit clusters consisting in one cluster with severe deficits (33.3%; general score of z=-1.48) and the other with a deeply compromised cognitive ability (9.55%; general cognitive score of z=-2.34). There were no significant differences between clusters in terms of clinical features at baseline (including diagnosis, positive and negative symptoms, medication), apart from the level of functioning that was significantly lower in the severely compromised cluster compared to the near normal cognition cluster. It emerged that majority (about 68%) of the patients from the near normal cognition cluster were responsive to treatment, whilst the majority of the selective and severely impaired clusters did not respond to treatment at 12-week follow-up. There were no significant results with regard to treatment response at 1-year FU. Discussion: Distinct patterns of cognitive impairments exist within FEP that might be characterized by different response to treatment. Clinical presentation at the onset of the illness is not useful in predicting response to Downloaded from https://academic.oup.com/schizophreniabulletin/article-abstract/44/suppl_1/S98/4957307 by guest on 27 July 2018