Finance analysis is an effective tool of evaluating the efficiency and performance of each business organization. It is important for actual investment made by the investors or own capital invested by the owners. Without financial analysis, a business organization is unable to identify the actual worth in the market. Financial analysis is advised to management that a sound found plans and policies are to be developed for the development of its business. It is same as in the interest of a human being's good health, medical authorities suggest a periodical medical examination. Thus, it is necessary activity of each business which is necessarily be performed at the end of each year. The financial analysis can be determined on the basis of various techniques. But, ratio analysis is one of the important techniques of analysis of performance of a business organization. In this paper, the company's performance appraisal has been explained using various ratios. The ratio explains the financial capacity of business.


Objective: Cerebral palsy (CP) is a neurological condition that occurs as a result of non-progressive damage in the immature brain and is characterized by impairment of muscle tone and posture. This study aims to evaluate the risk factors and imaging findings of patients with CP. Material and Methods: Medical records of patients with CP at the Pediatric Neurology Clinic of Cerrahpasa Medical School were evaluated retrospectively. Demographic and clinical characteristics were collected from medical records: Gestational age, birth weight, intrauterine growth retardation (IUGR), delivery mode, type of CP, risk factors, accompanying diseases, computed tomography (CT), magnetic resonance imaging (MRI), and electroencephalography findings were recorded. Results: A total of 169 patients were enrolled in the study. The mean age at diagnosis was 27.3±26.1 months. One hundred eight (66.2%) patients were term and 55 (33.7%) were preterm. The delivery mode was vaginal in 99 (58.6%) cases and cesarean section in 70 (40.4%) cases. Ninety-six cases (56.8%) were male and 73 (43.2%) were female. Birth weights were <2500 g in 59 cases (34.9%) and 2500–4500 g in 110 cases (65%). The types of CP were spastic (n=144, 86%), dyskinetic (n=13, 7.7%), mixed (n=6, 3.6%) and ataxic-hypotonic type (n=5, 3%). In subgroup analysis, 65 (38.5%) cases were quadriparetic, 43 (25.6%) cases were diplegic, 35 (20.7%) cases were hemiparetic, and 2 (1.2%) cases were monoparetic. The reasons for CP were asphyxia (n=99, 58.9%), low birth weight (n=61, 36.1%), prematurity (n=55, 32.5%), hyperbilirubinemia (n=16, 9.5%), meningitis (n=7, 4.1%), intracranial vascular processes (n=7, 4.2%), sepsis (n=6, 3.6%), hydrocephalus (n=5, 3%), genetic anomalies (n=5, 3%), and hypoglycemia (n=1, 0.6%). No risk factors could be determined in eight (4.7%) cases. Imaging techniques (CT and/or MRI) showed encephalomalacia, which was considered as the main finding of hypoxic-ischemic encephalopathy, in 45 (26.6%) cases. Imaging results of 15 (8.9%) patients were normal. Conclusion: This study results showed that asphyxia, low birth weight, and prematurity are the main reasons for the development of CP. Encephalomalacia is the most common imaging finding, but imaging may be also normal in some patients with CP.


Objective: The intension of the present study includes fabrication and optimization of mouth dissolving film loaded with Chlorothalidone by solvent evaporation techniques using two components and their three levels as multilevel Categoric design.
Methods: Major problem associated with the development of film loaded with BCS class II drug is to increase its solubility. Here the Chlorothalidone solubility achieved by co-solvents, such as methanol. After dissolving the drug in co-solvent, this drug solution is poured into an aqueous dispersion of Hydroxypropyl Methylcellulose E5 (HPMC E5) and Polyethylene glycol 400 (PEG 400). The two independent variables selected are factor A (concentration of HPMC E5) and factor B (concentration of PEG 400) was selected on the basis of preliminary trials. The percentage drug release (R1), Disintegration time in sec (R2) and folding endurance (R3) were selected as dependent variables. Here HPMC E5 used as a film former, PEG 400 as plasticizer, mannitol as bulking agent, Sodium starch glycolate as a disintegrating agent, tween 80 as the surfactant, tartaric acid as saliva stimulating agent, sodium saccharin as a sweetener and orange flavour etc. These fabricated films were evaluated for physicochemical properties, disintegration time and In vitro drug release study.
Results: The formulation F6 has more favorable responses as per multilevel categoric design is % drug release about 98.95 %, average disintegration time about 24.33 second and folding endurance is 117. Thus formulation F6 was preferred as an optimized formulation.
Conclusion: The present formulation delivers medicament accurately with good therapeutic efficiency by oral administration, this mouth dissolving films having a rapid onset of action than conventional tablet formulations.


Intraocular foreign bodies (FBs) are extraneous objects usually detected in the eyeball after trauma with metallic objects. As these can cause sight-threatening complications such as endophthalmitis and siderosis bulbi, early diagnosis and removal are essential for favourable outcome. However,


Objective: To evaluate the influence of preoperative moderate acute normovolemic hemodilution (ANH) with 6% hydroxyethyl starch(HES,200/0.5) on blood coagulation.Methods: Twenty ASA Ⅰ-Ⅱ patients scheduled for elective surgery were randomly assigned to receive moderate ANH with 6% HES.After induction of general anesthesia blood was withdrawn and collected before the onset of surgical blood loss,and at the same time replaced with HES.Measurements were obtained before and 15min after hemodilution and retransfusion of autologous blood.Results: After hemodilution APTT and PT were prolonged respectively from 30.50±4.50s and 12.66±1.03s to 34.48±3.62s and 14.14±0.86s(P0.01).After retransfusion both of them could be used to normal range(P0.01).Activated clotting time(ACT) had no changes all the while(P0.05).After hemodilution both Fib and CR decreased significantly(P0.01).Both of them increases significantly after retransfusion(P0.01).Plt after hemodilution is less than that of before hemodilution significantly(P0.01).PF decreased significantly(P0.01) and TP was significantly(P0.01) prolonged after hemodilution.Plt,PF and TP were resumed to a great extent(P0.01).Conclusions: There was influence to some extent of moderate ANH with 6% HES on the function of coagulation.And platelet function could be shielded in ANH.


This article highlights the increased expansion and complexity of the National Bureau of Standards (NBS) from 1904-1922. Samuel Stratton led a carefully chosen group of excellent scientists to produce the principal source of science-based measurement standards in the U.S. The list of services to the public, academia and to Federal agencies broadened. They instituted the Standard Reference Materials Service for industry, became part of the Department of Commerce, supported the physical development, production, and testing of materials needed during World War I, studied problems found in the new field of high altitude aeronautics, radio, and the dental industry, and worked in many more areas. After the war, Stratton successfully proposed that industry send their own scientists to work at NBS as guest researchers. These researchers helped to replace the many NBS staff members lost to higher industrial pay scales, thus maintaining the Bureau's progress on industry related projects. He was a man with enormous abilities that were the driving force that created that institution.


Calnexin is a molecular chaperone and a component of the quality control of the secretory pathway. We have generated calnexin gene-deficient mice (cnx−/−) and showed that calnexin deficiency leads to myelinopathy. Calnexin-deficient mice were viable with no discernible effects on other systems, including immune function, and instead they demonstrated dysmyelination as documented by reduced conductive velocity of nerve fibers and electron microscopy analysis of sciatic nerve and spinal cord. Myelin of the peripheral and central nervous systems of cnx−/− mice was disorganized and decompacted. There were no abnormalities in neuronal growth, no loss of neuronal fibers, and no change in fictive locomotor pattern in the absence of calnexin. This work reveals a previously unrecognized and important function of calnexin in myelination and provides new insights into the mechanisms responsible for myelin diseases.


The article has discussed the necessity structuring early warning mechanism first,proceed to investigation and discussion the problem how to building early warning mechanism,being going to pay attention to in having analysed early warning mechanism putting process into practice.


Objective: To compare the number of hits of students in cervical dilation assessment in dilation simulators with and without the use of direct visual validation. Methods: This is a cross-sectional study with 40 undergraduate obstetrics students from a public university in São Paulo, who assessed cervical dilatations in blind dilatation simulators, in three stages: in the first, they estimated dilations in the simulators; in the second, they sequentially compared the findings in simulators with a direct visual validation tool using the dominant hand and then the non-dominant hand; and in the third step, they simultaneously compared the estimates found in simulators with direct visual validation with the dominant and non-dominant hands. The outcome was the success of cervical dilation in dilation simulators or not, with a p-value ≤ 0.05 considered statistically significant. Results: We analyzed 240 assessments and computed the hits of students related to cervical dilatation assessment of simulators. There was an increase in the hit rate of 47.1% with the use of direct visual validation (OR= 4.689; 95%CI: 2.601-8.452; p<0.001). Conclusion: The use of direct visual validation increases the probability of hits by students in cervical dilation assessment in dilation simulators.


A robust empirical literature suggests that the development of one's political ideology is the product of an "elective affinity" between the discursive, socially constructed elements of ideological belief systems and the psychological constraints, motives, and interests of those who are drawn to those belief systems. However, most studies which support this elective affinity theory have been conducted in the West. In the present study, we tested the theory in China to see whether elective affinities between psychological traits and political ideology are more likely to be universal. Across a nationally representative sample (N = 509), we found initial support for the characterization of the leftright divide in China, albeit in reverse. Namely, the "liberal Right in China mostly evinces traits of the psychological Left in the West (e.g., lower intolerance of ambiguity), while the "conservative Left" mostly evinces traits of the psychological right in the West (e.g., higher system justification). Epistemic motives were most reliably related to political ideology, while existential and relational motives were more mixed; economic and political aspects of ideology were more closely linked to psychological traits than social/cultural aspects. The present findings provide an extension of existing theory and opportunities for further development.


In this article, the establishment and functioning of the Yam Organization are discussed. And also this study abaout the effects of the Yam Organization on the development of the Mongolian Empire. Mongols, who united culturally developed Eurasian countries under a single roof and thus extended their dominance, felt the need to pay attention to the postal organization upon the widening of the borders and the extension of the distances between the centre and the statep. This is mainly due to the fact that any empire, which has achieved to unite a wide geography under a single roof, has to find a systematic organisation to address all areas in order to be able to hold this geography permanently under its control.


Two new species of hydroids, Halopteris enersis sp.nov. and Halopteris schucherti sp.nov., from the Pacific coast of southern Chile are described and figured. Measurements and nematocyst data are provided for each species. Their morphological features are compared with those of other members of the genus, and comparative tables listing their peculiarities are presented.


Absolute parameters of 509 main-sequence stars selected from the components of detached-eclipsing spectroscopic binaries in the Solar neighbourhood are used to study mass-luminosity, mass-radius and mass-effective temperature relations (MLR, MRR and MTR). The MLR function is found better if expressed by a six-piece classical MLR ($L \propto M^{\alpha}$) rather than a fifth or a sixth degree polynomial within the mass range of $0.179\leq M/M_{\odot}\leq 31$. The break points separating the mass-ranges with classical MLR do not appear to us to be arbitrary. Instead, the data indicate abrupt changes along the mass axis in the mean energy generation per unit of stellar mass. Unlike the MLR function, the MRR and MTR functions cannot be determined over the full range of masses. A single piece MRR function is calibrated from the radii of stars with $M\leq1.5M_{\odot}$, while a second single piece MTR function is found for stars with $M>1.5M_{\odot}$. The missing part of the MRR is computed from the MLR and MTR, while the missing part of the MTR is computed from the MLR and MRR. As a result, we have interrelated MLR, MRR and MTR, which are useful in determining the typical absolute physical parameters of main-sequence stars of given masses. These functions are also useful to estimate typical absolute physical parameters from typical $T_{eff}$ values. Thus, we were able to estimate the typical absolute physical parameters of main-sequence stars observed in the Sejong Open Cluster survey, based on that survey's published values for $T_{eff}$. Since typical absolute physical parameters of main sequence stars cannot normally be determined in such photometric surveys, the interrelated functions are shown to be useful to compute such missing parameters from similar surveys.


Abstract Disclosure: T. Rave: None. J. Giunta: None. Hyperthyroidism is defined as excess thyroid hormone, most commonly due to Graves Disease. Thiomides are first line therapy, however more definitive options are radioactive iodine (RAI) or thyroidectomy. RAI enters thyroid follicular cells and destroys the thyroid tissue with beta ray emissions. Patients with Graves disease, toxic multinodular goiter, and thyroid cancer can benefit from RAI, but it is contraindicated in pregnancy, breast feeding, and severely uncontrolled thyrotoxicosis. Early side effects are pancytopenia, thyrotoxicosis, and later complications are bone marrow suppression and cancer. There are several reports of cerebral vascular accidents (CVA) after RAI therapy, however, there is limited research demonstrating whether CVA is a direct consequence of RAI or secondary to thyrotoxicosis. This case describes a possible RAI-induced CVA. A 60-year-old female with a past medical history of type 2 Diabetes Mellitus, hypertension, obesity, and Graves disease presented with altered mental status and gait instability for 1 day. She received RAI therapy 1 day prior to symptom onset for uncontrolled Graves disease. She was previously on Methimazole and PTU, however, both were discontinued due to an intolerable rash. As a result, she was maintained on a beta blocker prior to RAI. On presentation, she was afebrile, normotensive with a heart rate of 79. She was oriented only to person and place and had an unbalanced gait. Her Burch-Wartofsky score was 30, which was concerning for thyrotoxicosis. Her TSH was undetectable and EKG showed normal sinus rhythm. She was placed on atenolol, PTU and hydrocortisone. Her CT head was negative for acute disease, however, her MRI brain diagnosed an acute ischemic stroke. During admission, she had episodes of atrial fibrillation with rapid ventricular response. This patient presented with thyrotoxicosis after RAI therapy complicated by a CVA. It is important to note that on presentation she was reliably taking a beta blocker outpatient and her EKG was normal sinus rhythm making atrial fibrillation a less likely culprit of her CVA. Research has found that hyperthyroidism alone can lead to a prothrombotic state, however, additional literature reports that both hyperthyroid and euthyroid patients have an increased risk of CVA following RAI. Whether a CVA is secondary to thyrotoxicosis or a direct effect of RAI, this potentially life-threatening complication should be discussed with patients prior to treatment. Presentation: Friday, June 16, 2023


This paper summarized the development and operation experiences of DC filtering capacitors for HVDC transmission.It is clear,that our enterprise has a good grasp of design skill and manufacturing technology of DC filtering capacitors and installations.The application of the products in "De-Bo" project will lay a foundation of further expanded application of domestic capacitors for DC field.


The present invention is a patient, preferably to the use of any of the acetic ulipristal or a metabolite thereof in the prevention or treatment of breast tumors of patients with mutations in the BRCA1 gene.


By the investigation and experiment of soil erosion of scattered garden plot in Dianchi lake watershed, the article explains the law of soil and water loss in garden plot in Dianchi lake watershed, thinks that the value of SS from small scattered garden plots in Dianchi lake watershed is not the main source of soil and water loss. But the loss effects deeply the changes of vegetation. The scattered garden is potential soil erosion area.


Objective To explore the clinical effect of transurethral plasma kinetic resection used for Bladder neoplasm.Methods 72 cases were randomly divided into experimental group and control group,experimental group were given therapy of transurethral plasma kinetic resection,and control group were given therapy of traditional electrocision.Results The surgical time,blooding during surgery,hospital time(all P0.01) and complications(P0.05) of experimental group was significantly less than that of control group,it showed better surgical effect.Conclusion Transurethral plasma kinetic resection used for Bladder neoplasm,might be safe and effective,and can significantly enhance clinical effect,so it should be a deserved surgical type in clinical work.


Using the methods of modern materials science the researches and the comparative analysis are performed for the structural and phase states, dislocation substructure, mechanical and tribological properties of the surface of the thermo-mechanically strengthened and non-strengthened I-beam DP155 from low carbon steel used for mine monorails. It was found that accelerated cooling of the beam section in line 450 of the mill at "EVRAZ – Consolidated West-Siberian Metallurgical Plant" (rolling speed is 6 m/s, the water pressure on the sections of shelf cooling is 0.22 – 0.28 MPa, the temperature before the refrigerator is approximately 800 °С) forms a high defect surface layer structure characterized by higher (relatively to the unhardened state) values of hardness, wear resistance and scalar dislocation density. In the non-heat-resistant state, the microhardness of the samples is 2.70 ± 0.33 GPa, and Young's modulus is 269.6 ± 27.1 GPa. Thermo-mechanical hardening of the material leads to a decrease in its microhardness up to 3.30 ± 0.29 GPa and to an increase in the Young's modulus up to 228.2 ± 25.7 GPa, respectively. In addition, an increase in the range of microhardness values from 2.20 – 3.80 GPa to 2.64 – 4.60 GPa and a decrease in the Young's modulus range from 208.0 to 403.0 GPa to 184.1 to 278.2 GPa is established during thermomechanical hardening of steel. It is shown that the thermomechanical strengthening of steel leads to an increase in the wear resistance of the surface layer in approximately 1.36 times (the wear rate varies from 5.3·10 –5 mm 3 /N·m  to 2.9·10 –5 mm 3 /N·m) and an increase in the friction coefficient by 1.36 times (from 0.36 to 0.49). In the non-strengthened state the dislocation chaos structure is observed (the dislocation scalar density is (0.9 . 1.0)·10 10 cm –2 ). High-temperature rolling and subsequent accelerated cooling of the samples lead to the formation of a strip dislocation substructure in the grains of ferrite and a reticular dislocation substructure in martensite grains (the average scalar dislocation density in the surface layer is 4.5·10 10 cm –2 ). The possible reasons for the observed regularities are discussed.


This study examines whether from the late fifth to the peak of the recent sixth acquisition wave, acquiring firms in emerging economies created operating performance following transactions. The authors analyze whether the degree of threat from corporate governance and the legal environment influences value creation. Based on ninety-eight merger and acquisition deals from 1998 to 2006, this paper concludes that emerging market acquirers typically have good operating performance before transactions occur, but that the average adjusted operating performance over a three-year period following a merger transaction shows little improvement. In addition, the square relationship that exists between postacquisition performance and the level of ownership concentration provides evidence to support both the incentive and the tunneling effects of large shareholders. Furthermore, there is no significant difference in performance improvement related to the legal framework of the acquirers' home countries, but the legal quality of target nations does have an impact on acquisition performance. Finally, our results on firm-specific governance mechanisms complicate the usefulness of audit committees on company boards but support the crucial role of independent directors. The results for country-specific legal systems confirm that a secure legal environment can help curb the practice of using ownership to extract private benefits and lead to better performance by emerging market acquirers, although legal enforcement from public institutions that is too strong reduces value.


Diffuse x-ray resonant magnetic scattering, atomic-force microscopy, and magnetic hysteresis measurements are used to explore the relationship between the roughness and magnetic properties of interfaces between magnetic and nonmagnetic thin films. Bare Co films and Co films capped with magnetic and nonmagnetic thin films are investigated to elucidate why and under what circumstances the magnetic boundary differs from the chemical boundary. Competing models to explain why the magnetic boundary appears smoother than the chemical boundary are explored.


Parkinson's disease (PD) is a progressive, debilitating neurodegenerative disease that afflicts approximately every 1000th individual. Recently, activation of genomic transposable elements (TE) has been suggested as a potential driver of PD onset. However, it is unclear where, when, and to what extent TEs are dysregulated in PD. Here, we performed a multi-tissue transcriptional analysis of multiple patient cohorts and identified TE transcriptional activation as a hallmark of PD. We find that PD patients exhibit up-regulation primarily of human endogenous retrovirus (HERV) transcripts in prefrontal cortex tissue, prefrontal neurons as well as in blood, and we demonstrate that TE activation in the blood is highest at the time of PD diagnosis. Supporting a potentially causal association between ERV dysregulation and PD heterogeneity, reduced gene dosage of the TE repressor Trim28 triggers transcriptional changes highly correlated to those measured in animal models of synucleinopathy (PFF-injection), and importantly, to those exhibited by patients themselves. These data identify ERV up-regulation as a common feature of central and peripheral PD etiology, and highlight potential roles for Trim28-dependent TEs in stratifying and monitoring PD and treatment compliance.


The depth of anaesthesia (DOA) achieved is a result of the concentration of the anaesthetic drugs in the brain. Until recent years, there has been no simple, accurate and objective method for assessing the DOA or alerting the anaesthetist to a state of awareness. The monitoring of DOA is complex, and dependent on many factors, which vary between patients and operating procedures. A method that can be adapted for handling complex and inexact knowledge (e.g. DOA) within a computer program is fuzzy set theory. This paradigm seems to be specially suitable for medical processes, since it depends upon expert experiences which are not precisely quantifiable, such as patients' subjective sensations, interpretation of clinical signs and effects of instrumental accuracy.


Vedam and Barnes 1 compare small and large bore intercostal tube drainage for spontaneous pneumothorax and seem to conclude that large bore drainage is the appropriate management. This study seems to address a question which is no longer relevant. Their recommendation is in line with the American College of Chest Physicians consensus statement. 2 However, the British Thoracic Society study on management of pneumothorax 3 provided randomised trial evidence that aspiration was preferable to tube drainage and this has subsequently been shown once again in a further prospective randomised study in Europe, 4 which incidentally also confirmed the fallibility of consensus expert opinions. Not only were success rates better with simple aspiration but previous suggestions that patients treated with chest tubes had higher recurrence rates were confirmed. 5


In this paper English class is studied by introducing new ecological education concept. Starting from basic ecological theories, optimized ecological strategies and methods of classroom teaching have been studied. Through the analysis of the existing problems of the English class room teaching, new strategies have been brought forward. With a large amount of practices and deep study, a new model of Ecological English classroom teaching is built which has significant meaning in the further development of English teaching.


resistance Abstract. AZ31B was used as the basic material in electroless Plating of Ni-Co-P, The optimium formula and process conditions were obtained by using the orthogonal experiment methods. XRD, SEM and EDS were used to characterize phase structure,compositon and morphology of Ni-Co-P coating. The morphology,corrosion resistance, composition ,hardness,thickness and binding force of coating are measured and analysed. The optimum formula and the technological conditions were gained as follows:26.0g/L NiSO4 ·6H2O ,28.0g/L CoSO4·7H2O,24.0g/L NaH2PO2·H2O,80.0g/L Na3C6H5O7·2H2O,60.0g/L NH4F ,temperature of 90.0℃,0.001g/L KI, 0.05g/L SDBS ,the plating time of 2.0 h and pH of 8.0.Under this condition, the coating had stronger corrosion resistance, drop time for KMnO4 solution was 272s; The hardnesses was 229.60HV ;the deposition rate was faster, up to 53.33 g·m -2 ·h -1 ;thickness was 12.43 μm;the surface of the coating was uniform;the distribution of


The evolution of a quantum lattice gas automaton (QLGA) for a single charged particle is invariant under multiplication of the wave function by a global phase. Requiring invariance under the corresponding local gauge transformations determines the rule for minimal coupling to an arbitrary external electromagnetic field. We develop the Aharonov–Bohm effect in the resulting model into a constant time algorithm to distinguish a one-dimensional periodic lattice from one with boundaries; any classical deterministic lattice gas automaton (LGA) algorithm distinguishing these two spatial topologies would have expected running time on the order of the cardinality of the lattice.


As an important topic in computer vision and multimedia analysis, 3D shape recognition has attracted much research attention in recent years. For point cloud data and multiview data, various approaches have been proposed with remarkable performance. However, few works simultaneously employ the point cloud data and multiview data to represent 3D shapes, which is complementary and beneficial in our consideration. Moreover, existing multimodal approaches mainly focus on the multimodal fusion strategy or on exploring the relation between them. However, the intra-modality characteristic information and inter-modality complementary information are ignored in these methods. In this paper, we tackle the above limitations by introducing a novel Point-View Complementary Learning Network (PVCLN) to explore the potential of both the complementary information and characteristic information for 3D shape recognition. Inspired by the successful application of graph neural networks in capturing relations between features, we introduce a novel multimodal fusion strategy. Concretely, we first separately extract the visual feature from multiview data and structural feature from point cloud data. We then project the visual feature and structural feature into the same feature space to learn the complementary information between two modalities by modeling the inter-modality affinities. The characteristic information in each modality is also preserved by considering the intra-modality affinities. The intra-modality and inter-modality affinities compensate for the lacking characteristic information and enhance the complementary information in the feature learning process. Finally, the updated visual and structural features are further combined to achieve a unified representation for a 3D shape. We conduct extensive experiments to validate the superiority of the overall network and the effectiveness of each component. The proposed method is evaluated on the ModelNet40 dataset and the experimental results demonstrate that our framework achieves competitive performance in the 3D shape recognition task.


Deposition of metal thin films is well-established for vapour-based methods like atomic layer deposition (ALD) and chemical vapour deposition (CVD). The chemistry of the


To compare features of pelvic floor muscle function between men with and without incontinence after prostatectomy and men with no history of prostate cancer.


The over 60-year segregation, together with different political ideology and education systems, all lead to sharp difference in interpreting cross-strait history. Indeed, the way to understand history may be through texts and films too. The audi-video effects of films can offer the viewers direct impressions, which can be more communicative and effective too. Director Yi-Li's film, "The Knot", is so touching that the researcher attempted to adopt this film as an assistant teaching material to help students understand the differences in cross-strait historical development, while at the same time to observe the audiences' views after seeing the film. The post-view questionnaires show the following interpretations: the localization proposed by Taiwan has still been affecting the youngsters' ideas; besides, the Culture-Visiting Tour proposed by Mainland China still needs to be further advocated, so as to attract more to join the activities related. The cross-strait next generation needs to collaborate and trust each other, so as to set up the glory and brilliant century belonging to the Chinese. In a word, the touchstone to the glory is people's enthusiasm broad enough to provide balanced perspectives in cross-strait history.


The recycling of lubricating oil detergent from pretreated waste residue with xylene as diluent is studied by extraction centrifugation method. The effect of different dilution ratios( quality ratio of residue to solvent) on the washing time and recycling effect is investigated in detail. The results show that the recovery of lubricating oil detergent with stable quality from waste residue can reach 98. 0%- 99. 2%. The physicochemical properties and crystal grain size for the recycled and fresh lubricating oil detergent are compared. It is found that recycled lubricating oil detergent can meet the quality requirements.


In this chapter, the resource allocation and rate adaptation techniques are proposed using the MAC protocol. In this work, Hidden Markov Model (HMM) and Fuzzy logic techniques are used for resource allocation and physical layer data rate adjustment, respectively. In the first phase, the free available bandwidth in the channel is predicted based on the current traffic load of the nodes. The HMM is utilized for predicting the free bandwidth. New users are admitted after checking the predicted available bandwidth against the demand of each user. In order to estimate the exact physical transmission rate, the channel utilization, queue state, delay and the available free bandwidth are passed as input variables to fuzzy logic inference engine. Based on the outcome of the fuzzy logic, the exact physical rate can be estimated.


This paper presents the remote control of a mobile robot via internet. To solve the problem of delay time which is unpredictable, direct teleoperation architecture is proposed. This architecture allow s us to minimize the trajectory error of the robot movement which is controlled via the internet. This work also demonstrates the use of virtual reality in the context of the remote control. Virtual reality can be used in a conventional manner to simulate the behavior of a system, but also in parallel with the real system to improve quality control. To validate our work, we conducted teleoperation experiments in various places. Experimental results show the effectiveness of the proposed architecture.


Throughout the world, the establishment of special economic zones (SEZs) has found support among many developing countries. However, few African SEZs have proved successful. It is generally acknowledged that Mauritian SEZs are a model for success, particularly in terms of export diversification and integration into the Global Clothing Value Chains (GCVC). The contribution of this paper is to first examine the Mauritian export diversification policy experience, and for the first time, considers the test of three hypotheses – learning-by-importing, self-selection of markets and financial innovation using two firm-level survey data sets for a pooled sample and inter-firm comparison of exporters operating in the Mauritian clothing and textiles sector. Overall the regression results provide evidence to support two of the three hypotheses in that what primarily matters for performance are the use and productive inputs of labor and imported intermediate inputs consistent with learning-by-importing and the financial innovation capabilities of firms. From a policy perspective, the empirical findings of this study suggest that more careful attention should be paid to the type and allocation of public incentives to boost export performance. Policies that facilitate imported inputs and financial credit can make domestic firms more competitive and better integrated within the global markets.


THE MAJOR TWENTIETH-CENTURY Japanese novelist Soseki Natsume was Conrad's contemporary. Born in 1867, he died in 1916 at the age of forty-nine. As a novelist, he was as late a starter as Conrad, with his first success, I Am a Cat, being published in 1905 when he was thirty-eight. Soseki, as he is familiarly called in Japan, studied and taught English literature, spending two years in London (1900 to 1902) to familiarize himself with contemporary English writing at a time when Japanese interest in things English was especially intense. The Nigger of the "Narcissus" and The Mirror of the Sea figured in his library; he wrote an article on The Nigger, and he left notes on Typhoon, "To-morrow," "Youth," "Heart of Darkness," and "The End of the Tether."1A few comparative studies by Japanese Conrad scholars have compared Kokoro with Conrad's works (Oshimoto 1975, and Suzuki 1998). Some commentators on Soseki have also compared Kokoro with "Heart of Darkness" (Merivale 1988, and Ikeda 1992). To my knowledge, no critical work has compared Under Western Eyes with Kokoro. This essay also considers the possibility that Soseki's novel complexly and interestingly reflects his reading of Conrad.The proximity of the publication dates of the two novels - 1911 and 1914 - suggests that Soseki could have read Under Western Eyes before beginning to write Kokoro. He may have borrowed a copy of Under Western Eyes from his friend Tadaichi Hidaka, Professor of English Literature at Waseda University, Tokyo. A Conrad enthusiast, he paid a visit to Conrad at Oswalds in 1922.2 Hidaka's interest in Conrad dates to 1906 when he was lent a copy of "Youth," he thereafter ordered Conrad works from abroad, keeping abreast with Conrad's fiction as it appeared (Okuda 1998: 73). In April 1915, a year after Kokoro's publication, Hidaka published an article entitled "Conrad as a Neo-Romantic." Although it does not take up Under Western Eyes, there is an interesting preliminary remark: "After the publication of Under Western Eyes four years ago, Conrad can no longer be called a romantic. Therefore, in this article, I introduce Conrad through his works written prior to Under Western Eyes." Hidaka, then, had read the novel before this date. According to Hidaka, it was Soseki who lent him a copy of The Nigger of the "Narcissus. " Given their shared interest in Conrad, there is the possibility that Hidaka lent Soseki his copy of Under Western Ejes.Begun as a short story called "Razumov," Under Western Eyes appeared in serial versions in The English Review and The North American Review from December 1910 to October 1911 and was published in book form in the latter month (Knowles and Moore, 2000: 382-86). Kokoro also began as the title-story of a short story collection. Published serially in Tokyo's daily Asahi Shinbun [The Rising Sun] between April and August 1914, it was published in book form in September 1914. The novel, generally considered Soseki's masterpiece, was first translated into English as Heart by Ineko Kondo in 1941, and by Edwin McClellen simply as Kokoro in 1956.3 It has sold more than twenty million copies since its first publication (Matsumoto, 1994) and remains a best seller in Iwanamfs paperback series of modern classics ("Titbits," 1993: 64).Just as Under Western Eyes was written at a period during which Conrad suffered from poor health and acute anxiety (Najder, 1983: 352) Soseki wrote Kokoro after interrupting his writing because of illness. According to C. J. Dunn:When he resumed, his work had a sombreness in marked contrast to the cheerful tone of earlier novels: this was due partly to his personal suffering, but also to the ebbing away of the optimism that had pervaded Japan after her victory over the Russians,, when equality with the West seemed attained. In his last novels, Soseki shows a developed power of psychological analysis, and Kokoro is typical of this last period. (Dudley and Lang 1969: 4: 285)Critics have discussed Under Western Eyes in such contexts as Russian history, contemporary politics, narrative technique, and the psychology of its characters (see Knowles and Moore 2000: 384-86). …


This study investigated the effects of high pressure processing (HPP) on the barrier properties of eight multilayer films. Pouches made from these films were filled with distilled water, sealed and then pressure processed at 600 and 800 MPa for 5, 10 and 20 min at 45°C. Controls were similarly prepared but exposed to atmospheric pressure. After processing, all pouches were dried and their oxygen, carbon dioxide and water vapour permeance determined. Films used in this study were PET/SiOx /LDPE, PET/Al2O3/LDPE, PET/PVDC/nylon/HDPE/PE, PE/nylon/EVOH/PE, PE/nylon/PE, metallized-PET/EVA/LLDPE, PP/nylon/PP and PET/PVDC/EVA. Results showed that metallized PET was most severely affected by HPP, as its permeance values for oxygen, carbon dioxide and water increased as much as 150%. Copyright © 2000 John Wiley & Sons, Ltd.


The application of sputtering in a mixed gas of Ar and N 2 to Al 80 Zr 20 resulted in the formation of compositionally graded amorphous Al(Zr, N) film. By changing continuously the partial pressure P N of N 2 from 0.03 to 0. 13 Pa in a total Ar+N 2 pressure of 1 Pa, the resulting phase consists of only amorphous Al(Zr, N) in the whole P N range. As P N increases, the wavevector at the peak position of the amorphous halo in the X-ray diffraction patterns decreases continuously and the crystallization temperature increases to temperatures above 773 K. The Knoop hardness and the electrical resistivity measured along the amorphous film thickness increase from 660 to 2120 and from 4.0×10 -6 to 1.3×10 -4 Ω m respectively with increasing N 2 content


We study Thurston's norm on the second homology of a 3-manifold. The novelty of our approach consists in the use of methods of the C∗algebra theory. Namely, for Stallings' fibration M with pseudo-Anosov monodromy, we associate a C∗-algebra whose K-theory gives rise to an algebraic number field K. We show that the trace function on the ring of integers of K induces a norm on the second homology of M . Further developments of this theory are discussed.


The democratic theory discloses that the democratic systems are imperfect and full of contradictions. One of them is the capacity to regulating the national target, what is not into the necessities and the imperatives of contemporary internationalization. Therefore, endowed with demanding of international insertion and qualified for the development degree where they are considered, democratic contemporary States are marked by the search for more efficient, transparent and inclusive domestic politics each time, at the same time where imperative of circulation of goods and people same States create distinct obligations for these. With this, the qualification of an orbit of domestic laws becomes visible, at the same time, the difficulty to guarantee rights of circulation of people. This article is focused on the philosophical principles of part of the democratic theory in which it has to the question above


Osteochondritis dissecans (OCD) of the talar dome is relatively common, however, OCD of the talar head is extremely rare. We present two cases of OCDs of the talar head. This report describes the natural history of this rare condition and its evolution until skeletal maturity. The literature of OCD in this unusual location is reviewed.


For multi-angle plane-wave (PW) imaging, Delay-Multiply-and-Sum (DMAS) beamforming has been used to improve the image resolution and contrast by introducing signal coherence into the image display. Signal coherence can be extracted in the dimension of either PW transmit angle (Tx) or receive channel (Rx). Nonetheless, excessive signal coherence may compromise the speckle quality and thus degrade the contrast-to-noise ratio (CNR). In this study, minimum-variance (MV) estimation is combined with DMAS beamforming to increase the image resolution without excessive signal coherence while the background speckle quality is better maintained. In the proposed Tx-MV-DMAS beamforming, low-resolution images are firstly constructed for all available PW transmit angles to generate the transmit vector. After magnitude-scaling the transmit vector by p-th root while maintaining the phase, the MV weighting is adaptively estimated for each image pixel and then the high-resolution image is produced by weighted summation of the transmit vector. Finally, the magnitude of the high-resolution image is restored by p-th power to introduce the signal coherence in DMAS beamforming. PICMUS simulation and vivo data are used to compare the performance of Tx-MV-DMAS with the conventional Tx-DMAS and CPWC.B-mode images show that the Tx-MV-DMAS offer significant improvements over Tx-DMAS in terms of image resolution and contrast while the background speckle remains visually comparable.


By applying the theory of mood in systemic-functional grammar,this paper analyzes the interpersonal meaning in "Hills like White Elephants".Through the analysis,the attitude that the man and the woman adopt towards each other is perceived and the relationship between the man and girl is revealed,thus the feasibility of interpreting literary works from the perspective of systemic-functional grammar is proved.


In a previous essay I contrasted Eric Voegelin and Rosenstock-Huessy's interpretation of Christianity and revolution, essentially arguing that at the heart of their different appraisals of revolution was Eric Voegelin's Platonism. I wish to review the topic, not because I think that was wrong, but this time I am interested in stressing the virtues of each rather than what I consider the deficiencies of one in relationship to the other. I argue here that Voegelin is primarily the voice of a diagnostician pointing out the historical pathologies of mind that give lead to revolt. He is also deeply opposed to the modern's unreal elevation of the self – its gnostic move – and the denial or imminentization of God into history and progress, the failure to appreciate the symbolic ordered relies upon the necessity of maintaining God as a beyond in relation to society, man and world. Rosenstock-Huessy likewise is concerned that the failure of moderns to understand the sign and significance of God is disastrous. He too is deeply opposed to modern gnosticism and the pathologies that come out of it, but he is also interested in something that is not Voegelin's primary concern – mainly the role of providence in history. Although I show that Voegelin's Augustinianism makes him more compatible with Rosenstock-Huessy's analysis than may at first be realized. Both in their different ways call upon and develop Augustine, and taken together bring out different aspects of what is intrinsic to the Christianization of society.


The discovery by Kool and coworkers that 2,4-difluorotoluene (F) mimics thymine (T) in DNA replication has led to controversy regarding the question of whether this mimic has the capability of forming hydrogen bonds with adenine (A). Recently, we have provided evidence for an important role of both hydrogen bonding and steric effects in the replication of DNA. In the present work, we extend our study to mimics (GFC′N′ and CN′NF) of the bases guanine (G) and cytosine (C). We address not only the question of the strengths of the hydrogen bonds in GFC′N′CN′NF as compared with those in GC but we focus in particular on the nature of these interactions. Thus, we have analyzed GFC′N′CN′NF and GC at the BP86/TZ2P level of density functional theory (DFT). In line with previous experience, this approach is shown to achieve close agreement with the available data from ab initio computations and experiment: the complexation energy of GFC′N′CN′NF (-4.1 kcal/mol) is confirmed to be much weaker indeed than that of GC (-26.1 kcal/mol). Interestingly, the weak hydrogen bonds in GFC′N′CN′NF still poses a significant orbital interaction component that resembles the situation for the more strongly bound GC, as follows from (1) an analysis of the orbital electronic structure of GFC′N′CN′NF and GC, (2) a quantitative decomposition of the GFC′N′CN′NF and GC bond energies, as well as (3) a quantitative decomposition of the charge redistribution associated with the GFC′N′ CN′NF and GC interactions based on the Voronoi deformation density (VDD) method. The VDD method allows us to decompose the charge redistribution ΔQ per atom into a component associated with the Pauli repulsive orbital interactions and a component associated with the bonding orbital interactions: ΔQ = ΔQPauli + ΔQoi. Implications of our findings for the mechanism of DNA replication are discussed. © 2006 Wiley Periodicals, Inc. Int J Quantum Chem, 2006


(IL-1a) and caspase-3 expression by FDPC in monoculture or cocultured with HMVEC Finally, we asked whether the two drugs could protect endothelium against oxidative stress occurring during ageing, skin wounding and inflammatory responses. As IL-1a is a cytokine prominent in these events, and acts as a negative hair growth regulator, we decided to evaluate the effects of MXD and Sh-Polypeptide 9 on its endothelial release. HMVEC were treated with H2O2 (400 lM, 2 h) to induce a strong oxidative stress. As expected, this stimulation evoked a strong increase of IL-1a levels in endothelial medium (24 h). The lowest MXD concentration slightly (but non-significantly) reduced IL-1a production that was dramatically prevented by the lowest concentration of Sh-Polypeptide 9 (Fig. 2e, Table S1). The same trend was measured for the apoptotic marker caspase-3 (Fig. 2f). No further changes were observed in the presence of FDPC. Conclusions We have recently shown that FDPC strongly support endothelial survival, proliferation and tubulogenesis in insert-based cocultures(7). Here, this approach was employed to investigate the activity of MXD and Sh-Polypeptide 9 (VEGF-like biomimetic peptide) on HMEC-FDPC crosstalk. The results reveal that Sh-Polypeptide 9 promotes endothelial tubulogenesis and VEGF production more efficiently than MXD, in particular at low concentrations. In addition, the VEGF-like biomimetic peptide is more powerful on b-catenin expression by FDPC and on endothelial protection from oxidative stress. In conclusion, our in vitro study points to Sh-Polypeptide 9 as a promising molecule; however, only further detailed mechanistic studies, together with 'in vivo' and clinical trials, will establish its positive effects against hair loss. Acknowledgements E.B. performed the research, analysed the data and wrote the manuscript. F.G. designed the research study. A.Z. contributed essential reagents. L.M. designed the research study, wrote the manuscript and contributed essential reagents. We acknowledge funding from Rottapharm-Madaus. Conflicts of interest None declared Supporting Information


We present a randomized inference algorithm for regular tree languages. The algorithm takes as input two disjoint finite nonempty sets of trees P and N, and outputs a nondeterministic finite tree a ...


This paper presents a probabilistic approach for the estimation of the angle between the optical and visual axes (angle kappa) in infants. The approach assumes that when patterned calibration targets are presented on a uniform background, subjects are more likely to look at the calibration targets than at the uniform background, but it does not require accurate and continuous fixation on presented targets. Simulations results show that when subjects attend to roughly half of the presented targets, angle kappa can be estimated accurately with low probability (< 1%) of false detection. In experiments with five babies who attended to the calibration target for only 47% of the time (range from 26% to 70%), the average difference between repeated measurements of angle kappa was 0.04 ± 0.31°.


The recrystallization of CL-20 and HNFX to form different polymorphs was investigated by employing combinations of computations (polymorph predictions with and without the presence of the solvent molecules in the molecular dynamics based calculations) and experimental analyses, including micro-crystallization under a myriad of conditions, novel means of crystallization, analysis of polymorphs using X-ray powder diffraction, and Rietveld analysis, and the use of conventional methods including DSC, TGA, polarized microscopy and SEM (with the experimental results reported in Part II of this paper). In the investigation all three groups of solvents: polar protic, non-polar aprotic, and dipolar aprotic solvents were employed. Our computations have revealed (in agreement with earlier studies) that polymorphs with various densities for both CL-20 and HNFX are possible. However, as part II of this paper will show although the experiments revealed different polymorph types, α, β, γ, ϵ for CL-20 under different recrystallization conditions all of our experimental work for HNFX have resulted in crystals pertaining to Ci R-3, which is the only known polymorph of HNFX.


The objective of this work was to evaluate the supplementation of an enzymatic complex based on xylanase, β-glucanase and phytase in light commercial egg laying feeds at peak egg production,performance and egg classification. A total of 288 laying hens of the Hy-Line W36 breed were used in a completely randomized design in split plot with four treatments and six replicates of 12 layer each in four periods of 21 days each. The experimental rations were formulated based on corn and soybean meal, consisting of four types of ration: CP ration - positive control (100% recommended metabolizable energy without enzymes), CN ration - negative control, reductions in 75 kcal of metabolizable energy, 0.12 percentual points (pp) of Ca and P available, CN Ration + 60 g/t Enzyme Complex and CN Ration + 100 g/t Enzyme Complex. The enzyme complex was composed by: xylanase = 12,000 u/g; beta-glucanase = 2500 u/g and phytase = 5000 u/g. The variables evaluated were: average egg production (egg%/ layerday), mean egg weight (g), mean feed intake (g/layer/day), feed conversion per egg mass, and classification according to weight. There was no interaction between the treatments and the evaluation periods (P> 0.05). It is possible to observe that the egg production was influenced by the nutritional reductions of the rations and the inclusion of 100 g/t of the enzymatic complex made it possible to recover the egg production rate, matching the layers of the positive control treatment (P<0.01). Feed intake was higher (P<0.05) for birds receiving 100 g/t enzyme complex compared to hens fed with ration without addition of enzyme complex (negative control). The weight of the eggs responded (P<0.01) to the nutritional reductions of the rations, being lighter in the negative control treatment, but with recovery when adding 100 g/t enzyme complex. The feed conversion was worse (P<0.05) for laying hens fed the feed with 60 g/t of the enzymatic complex tested, mainly due to the lower egg production observed in this treatment. The use of 100 g/t of the xylanase, beta-glucanase and phytase-based enzyme complex for feed formulations with nutrient reductions at 75 kcal ME/kg, 0.12 pp Ca and 0.12 pp P is recommended for laying hens Egg production in order to maximize performance and improve the classification of eggs produced.


Graduate credit instruction is provided to professional engineers at their worksites by the Off-Campus Graduate Education Program and Columbia Video Network. Instruction is either through a live two-way video link or videotapes. The programme offers substantial benefits to the university, to industry and to the off-campus students themselves. The future for such programmes is a challenging one and will be affected by such factors as the need for universities to diversify away from their traditional functions; the advantages to industry of being able to select the best courses and institutions, irrespective of location; continuing down-sizing of technology-based companies; and the need to serve displaced workers.


Abstract Suppression of thermal expansion is of great importance for industry. Negative thermal expansion (NTE) materials which shrink on heating and expand on cooling are therefore attracting keen attention. Here we provide a brief overview of NTE induced by intermetallic charge transfer in A-site ordered double perovskites SaCu3Fe4O12 and LaCu3Fe4−xMnxO12, as well as in Bi or Ni substituted BiNiO3. The last compound shows a colossal dilatometric linear thermal expansion coefficient exceeding −70 × 10−6 K−1 near room temperature, in the temperature range which can be controlled by substitution.


Laryngeal squamous cell carcinoma (LSCC) is one of the most common head and neck cancers, with high mortality and incidence. MicroRNA‐26a (miR‐26a) is involved in the development and progression of several tumours. However, the roles of miR‐26a and its target CKS2 in LSCC progression are not yet clear. The mRNA and protein expression was determined using RT‐PCR and Western blotting assay, respectively. Cell proliferation was detected using a Cell Counting kit‐8 assay (CCK‐8). Transwell assay was used to evaluate cell migration and invasion. Dual‐luciferase reporter assay was applied to determine the relationship between miR‐26a and CKS2. In addition, a tumour xenograft model in nude mice was established to further determine the effects of miR‐26a on tumourigenesis. In this study, we found that miR‐26a level was down‐regulated in LSCC tissues and cell lines, while CKS2 expression was increased. Cell proliferation, migration, invasion and the expression of MMP2 and MMP9 was suppressed by miR‐26a overexpression, but enhanced by inhibition of miR‐26a. Dual‐luciferase reporter assay demonstrated that CKS2 is a direct target of miR‐26a in AMC‐HN‐8 cells. Overexpression of miR‐26a caused a significant reduction in CKS2 expression, and reinforced expression of CKS2 abolished the tumour‐suppressive function of miR‐26a. Moreover, miR‐26a inhibited tumour growth in vivo. Taken together, miR‐26a inhibited proliferation and tumourigenesis of LSCC via targeting CKS2 in vitro and in vivo.


Higher education institutions have various ways to manage email communications and implement architecture that offers reliable service at reduced cost. This paper reports the results of study of email options used by higher education institutions. The two major email architectures that education institutions can implement are traditional on-premise and cloud services. This research finds that many institutions are shifting from on-premise to cloud based email which offer significant benefits as reduced cost and maintenance but have various risks related to privacy and confidentiality of student information. A hybrid model is a combination of on- premise and cloud services which offers benefits of clouds with low risks. This research will help higher education institutions who want to transition to the cloud understand risks associated with migrating and provides ways to balance the benefits and risks.


Using the resources of the methodology of theory of science we propose a rational reconstruction of Duhem's conception of science, interpreting it as a normative theory of the dynamics of knowledge. Such a reconstruction helps to establish that Duhem cannot be classified as a conventionalist/pragmatist as proposed in the standard interpretation, and, furthermore, that Duhem proposes to construct a conception of science as a middle way between a classical metaphysical conception and a conventionalist/pragmatist conception. The methodological strategy for this middle way is the proposal of a structural and convergent realism. Duhem replaces the transcendental subject of the classics with a transcendental theory to be reached by a dynamic process.


We focus on the Probable Maximum Precipitation (PMP) in the Upper Tone River basin, through weather conditions change. In order to evaluate total amount and distributions of heavy rainfalls, WRF model is used. The results are summarized as follows: (1) The increase of relative humidity in the atmosphere affects not only total rainfall but also its temporal variation and it also makes peak time earlier. Moreover it may generate a first peak before main peak rainfall, which will affect the initial loss of rainfall and increase maximum discharge. (2) The increase of wind speed affects not only total rainfall but also spatial distribution of rainfall. (3) Moisture fluxes show high correlation with total rainfall through grid point value (GPV) data from meso-scale objective analysis and WRF model calculation in the upper Tone River Basin, which clearly suggests they can be used as a suitable parameter to estimate PMP.


Early in the COVID‐19 pandemic, Australian donors aged 70 and over were advised to temporarily stop donating. The aim of this research was to understand the factors associated with some of these donors continuing to donate despite the advice, and whether adherence to the advice had negative implications for donor retention.


PURPOSE: To provide a new protease that is useful for treatment of the morbid states in which an excessive amount of tumor necrosis factor(TNF) is endogeneously formed or is dosed externally. CONSTITUTION: This invention provided a new protease that can cleave the cell-bound tumor necrosis factor receptor (preferably P55 TNF receptor) into the soluble TNF and the receptor. This protease is prepared through the gene recombination technique. COPYRIGHT: (C)1995,JPO


We examine the allocation of a limited pool of matching funds to public good projects using Quadratic Funding. In particular, we consider a variation of the Capital Constrained Quadratic Funding (CQF) mechanism proposed by Buterin, Hitzig and Weyl (2019) where only funds in the matching pool are distributed among projects. We show that this mechanism achieves a socially optimal allocation of limited funds.


Collision-induced dissociation of complexes, Ag+/NH2CH2(CH2) n CH2NH2, where n has values of 0, 1, 2 and 3, show loss of one H2 molecule at low energies. For the largest complex (n = 3), a second H2 molecule is also lost. For complexes with n = 0 and 1, loss of AgH (the only pathway observed in the fragmentation of Ag+/monoamine complexes) also occurs at low collision energies and this becomes the dominant fragmentation pathway at centre-of-mass energies above 2 eV. For complexes with n = 2 and 3, negligible amounts of product ions resulting from loss of only AgH were formed. However, for these complexes, the major products at higher collision energies result from loss of either AgH plus NH3 or, more likely, H2 plus AgNH2; the product ions are postulated to be cyclic iminium ions. Density functional theory (DFT) calculations (B3LYP with a DZVP basis set) on Ag+/NH2CH2(CH2)2CH2NH2 showed the loss of H2 followed by AgNH2 to have a slightly lower barrier than loss of AgH plus NH3. For complexes with n = 2 and 3, there are minor losses of various combinations of AgH, H2, 2H2 and NH3. Reaction profiles for the losses of H2 and AgH from all four Ag+/α,ω-diamine complexes have been examined computationally using DFT calculations. The second step on the reaction profile, loss of either H2 or AgH from the complex between Ag+ and α-amino-γ-imino-propane, Ag+/NH2CH2CH2CHNH, has also been calculated. The highest energy transition state on the profiles to loss of both H2 and AgH from the smallest complex (n = 0) are identical; on all the other profiles, the barrier for H2 loss is lower than that for AgH loss (by 2.5 kJ mol−1 when n = 1, by 13.4 kJ mol−1 when n = 2 and by 33.0 kJ mol−1 when n = 3). Fragmentation of the ligand backbone occurs most extensively for ions derived from the Ag+/NH2CH2CH2CH2NH2. After loss of H2, the product ion, Ag+/NH2CH2CH2CH = NH fragments via a transition state in which the CH2–CH2 bond is breaking, while a 1,5-hydrogen shift from one nitrogen to the other is occurring. Cleavage of the carbon chain of NH2CH2CH2CH = NH2+ occurs at relatively low energy; DFT calculations provide a mechanism by which H2C = NH plus CH3CH = NH2+ are produced.


Using the method of literature review and logical analysis,this paper discussed the content,the status quo of the change and path of physical education.teaching methods.It concluded that: physical education teaching methods should include physical education.teachers and students' thinking mode and behavior mode,which decide the behavior mode in the physical education teaching.Facing the dilemma of the new curriculum reform,the paper proposes specific reform path in teaching methods:shifting from the "teacher-centered" concept to the "student-centered" idea;further implementing and improving the "student-centered" physical education teaching behavior.


In this paper,a wavelet noise elimination method is applied to fault diagnosis of interturn short-circuit in turbogenerator rotor windings.While the generator is operation with load,EMF signals on detecting coil are treated with noise elimination by using wavelet analysis method and combining all signals characteristics and frequency scopes of it.Practical examples have shown that this method is effective to realize noise elimination and applicable to on-line checking for interturn short-circuit in turbogenerator rotor windings.


Some fundamental properties of maximal open sets are obtained,
such as decomposition theorem for a maximal open set. Basic properties of intersections of maximal open sets are established, such as the law of radical closure.


With the development of Internet,Web application has been more popular and complicated.Dynamic Web statistic chart is a typical case.With the development of developing technology,some open source projects become more infective for open and free,and are implemented in many projects. This paper introduces a kind of open source implementing dynamic statistic chart on Web based on JFreeChart engine,describes the display theory of JFreeChart.The B/S developing pattern based on JSP and Java Bean has been the major technology of Java Web applications nowadays.This paper gives a typical application,analyses with an example in a practical project and finds a way to develop dynamic Web statistic chart.


Spectrum efficiency and energy efficiency are two critical issues in designing wireless networks. Through dynamic spectrum access, cognitive radios can improve the spectrum efficiency and capacity of wireless networks. On the other hand radio frequency (RF) energy harvesting has emerged as a promising technique to supply energy to wireless networks and thereby increase their energy efficiency. Therefore, to achieve both spectrum and energy efficiencies, the secondary users in a cognitive radio network (CRN) can be equipped with the RF energy harvesting capability, and such a network can be referred to as an RF-powered cognitive radio network. In this article we provide an overview of the RF-powered CRNs and discuss the challenges that arise for dynamic spectrum access in these networks. Focusing on the trade-off among spectrum sensing, data transmission, and RF energy harvesting, we then discuss the dynamic channel selection problem in a multi-channel RF-powered CRN. In the RF-powered CRN a secondary user can adaptively select a channel to transmit data when the channel is not occupied by any primary user. Alternatively, the secondary user can harvest RF energy for data transmission if the channel is occupied. The optimal channel selection policy of the secondary user can be obtained by formulating a Markov decision process (MDP) problem. We present some numerical results obtained by solving this MDP problem.


We analyze the relationship between wage distribution, degree of redistribution of the Social Security and effective retirement age. We develop a two-staged political economy model. In the first stage government chooses the redistribution level of the Social Security Program, according to three different criteria. In second stage the retirement age is elected through a majority voting process by agents with different wages, knowing exactly the redistribution level and voting accordingly. We analyze the different elected retirement age under each government criterium.


Optical telecommunication will be the next technology for wide-band Earth/space communication. Uncompensated propagation through the Earth's atmosphere (e.g., scintillation and wavefront tilt) fundamentally degrade communication to distant spcaecraft.


In this article, we consider a general bilevel programming problem in reflexive Banach spaces with a convex lower level problem. In order to derive necessary optimality conditions for the bilevel problem, it is transferred to a mathematical program with complementarity constraints (MPCC). We introduce a notion of weak stationarity and exploit the concept of strong stationarity for MPCCs in reflexive Banach spaces, recently developed by the second author, and we apply these concepts to the reformulated bilevel programming problem. Constraint qualifications are presented, which ensure that local optimal solutions satisfy the weak and strong stationarity conditions. Finally, we discuss a certain bilevel optimal control problem by means of the developed theory. Its weak and strong stationarity conditions of Pontryagin-type and some controllability assumptions ensuring strong stationarity of any local optimal solution are presented.


In this paper, we propose a fingerprint verification system using two different modules: the automatic classification of fingerprints which is based on the minutiae-matching algorithms and the verification-search technique which is based on genetic algorithms. Our experiments on a large set of fingerprint images show that our approach is highly promising. Its performance shows a great flexibility in recognizing a person very quickly with an error-prone of at most 1%.


Abstract Hafnium carbide is one of the materials with the most potential that can be used for high temperature oxidation resistant coatings. So far, HfC coatings are mainly being produced by chemical vapour deposition technique. In this work, HfC coatings were produced using a reactive magnetron sputtering method. The reactive gas used in these experiments was mixture of CH4 and H2. The study is focused mainly on the effect of process parameters, applied radio frequency (RF) power, process pressure and reactive gas flow, on the deposition rate and crystal structure of the deposited HfC coatings.


The effects of fasting and feeding on the activity and kinetics of the hepatic microsomal L-thyroxine (T4) 5′-monodeiodinase enzyme system (5′D) responsible for generating 3,5,3′-triiodo-L-thyronin...


Insolvency practitioners play a critical role in supporting the Department to effectively administer FEG. In addition to verifying the eligibility and unpaid entitlements of redundant workers, as a primary contact point for employee creditors of the insolvent entity, insolvency practitioners are often the first port of call for employees enquiring about the status of their unpaid employee entitlements and when and how they will be paid.


From intension of manpower resources management,this text analyzes the current situation and existing problems of the management of manpower resources in small and medium-sized enterprises of our country,and proposes a series of suggestions and countermeasures of feasibility about upgrading the idea in terms of enterprise,making rational long-term planning,and paying attention to the training of the staff's skills.


Abstract
 Emerging issues such as climate change, ozone layer depletion and global warming have driven policy makers to put a cap on the emission of pollutants through various legislations. Policies and legislations are the most important instrument for the proper functioning of any sector of society. Through legislative framework and regulatory policies, the fissure between the 'natural environment' and 'human society' can be bridged, which is the need of the hour in order that sustainable development and protection of the environment can progress in parallel. Legislation serves as a valuable tool for educating institutions about their responsibility in maintaining a healthy environment. Legislation has already been put forth at national and international levels but its proper implementation and enforcement has gone unseen. Witnessing the present scenario, more stringent laws need to be framed, especially by global leaders. This chapter highlights the importance of laws and policies and their role in reducing air pollution. It also critically analyses various regulatory measures and policies in the most polluted countries of the world, and what has been achieved through treaties and conventions organized by the United Nations, such as the Kyoto Protocol and the Montreal Protocol.


The coupling of two vehicles by a rigid tow bar needs special attention in simulation studies and experiments. Two different mathematical vehicle models are used in the research. For the vehicle control, two different concepts based on physically clear ideas are studied. Stability and path tracking performance are investigated. An approach for the handling of emergency cases is proposed. Experimental research is carried out using two passenger cars. The towed vehicle is equipped with a steering actuator replacing the driver. Road tests are performed with the two research vehicles to verify the simulation results for low speed maneuvers. (A) For the covering abstract see IRRD 887751.


Background: iron-deficiency and anaemia in pregnancy is common but surprisingly challenging, and has lead to inconsistencies in management usually due to lack of clinical guidance. Methods: A Maternity Blood Optimisation (MBOP) strategy has been adapted from the Australian Red Cross Blood Service. However, specific challenges remain in applying evidence to practice. The challenges are: inconsistent treatment thresholds; the influence of inflammation on iron metabolism; and oral iron dosing regimens.Pre-pilot data: 82% 2nd trimester women were iron-deficient and 7% had late stage iron-deficiency anaemia.Discussion: Although challenges in interpreting evidence remain, knowledge advancements do suggest improved clinical pathways based on an early and consistent approach


According to the fact that humans and animals show marvelous capacities in walking on irregular terrain, there is a strong need for adaptive algorithms in walking of biped robots to behave like them. Since the stance leg can easily rise from the ground, the problem of controlling the biped robots is difficult. In other words, the biped walkers have fewer actuators than the degrees of freedom. So they are underactuated mechanical systems. In this paper according to the humans and animals locomotion algorithms, the stability of an underactuated biped walker having point feet is investigated by central pattern generators. For tuning the parameters of the CPG, an effective energy based consideration is used. This robot model in single support phase is a mechanical system with one degree of underactuation. Reflexes from musculoskeletal system to CPG are modeled by tonic stretch reflex terms and nonlinear terms, where these reflexes act as a feedback loop. Also according to the dynamics of the muscles, proportional (P) controllers are used at joints for tracking


In this paper,3-dimensional finite element method is used to simulate and analyze the whole process temperature field and temperature stresses of Dagangshan arch dam block NO.14,the general law of the arch dam temperature field and temperature stress variation is obtained.In the simulation analysis,the thermodynamical properties of the arch dam materials,concrete placement process,ambient temperature variation,arch dam contract joint grouting and reservoir impoundment procedure are considered.


We use air conditioner or heater when driving a car in a hot summer or a cold winter. When you want a straight air blow or air conditioning only for the lower bottom, all these air movements are controlled by an actuator. In this thesis paper, we will look into characteristics, pros and cons of DC motor and STEP motor, actuator's sources of energy; correlation between OEPN-LOOP SYSTEM and CLOSED-LOOP SYSTEM; type of mechanics simulation programs of actuator; and characteristics of automotive air conditioner actuator.


This study investigates the sarcastic utterances found in two American movies. The data for the research were dialogues containing sarcastic expressions found in the movies Fantastic Four (2005) and its sequel Fantastic Four: Rise of the Silver Surfer (2008). The data were analyzed and categorized according to their forms using Camp's theory (2011). The sarcastic utterances were also classified according to their functions using Leech's theory (1983). The results indicate that in terms of form, illocutionary sarcasm (60%) was most frequently used by the characters in the movies, which suggests that the characters in the movies tend to express their sarcasm through illocutions. In terms of function, sarcasm in the movies was more commonly (56%) used for collaborative purposes. The results of the research also suggest that there has to be a clear context in understanding sarcastic expressions, and the interlocutors must share some sufficient common ground in employing sarcasm.


Gels were prepared from tetraethylorthosilicate (or tetramethylorthosilicate), aluminium sec-butoxide, barium acetate, and zinc acetate and converted to «amorphous» oxide powders through an appropriate drying and heat treatment. The effect of various factors such as solvent, composition, chelating agent, and reflux conditions on the synthesis and character of the gels were studied. The physical and chemical reactions occurring during heat treatment were followed by differential thermal analysis and thermogravimetric analysis


Introduction: Nurses spend more time with patients than any other member of the healthcare team. They play a critical, active and very important part in controlling cancer patients' pain and alleviating suffering. This study aimed to explore current nursing practices in the oncology hospital and the level of knowledge they possess about pain and its management in clinical settings.
Methods: This is a transversal type study developed on the basis of cluster sampling type on nurses in the Oncology Hospital, Tirana. The study was conducted in the period 2016-2018 and the sample consisted of 119 nurses.
Results: In total, 119 questionnaires were completed by oncology hospital nurses. Regarding the gender of was seen a predominance of women nurses compared to men 78.15% and 21.85% respectively. Nurses between the age 30 until to 39 years old were 34.4% of participants. Nurses of different gender, education level, and place of birth showed statistically significant difference. Only 23.5 % of nurses had pain training and education, and less than half of nurses (43.7%) had 5-10 years in oncology hospital. In this study, knowledge and practice of nurse's participant on non-and pharmacological pain management were more than 55%. Related to the pain assessment 36.1% were based on the information provided by the patients, while 31.1% of nurses had used the visual analogue scale for pain assessment. According to the ways of pain management, almost 76.5% of nurses think that the best ways of pain management were pharmacology and 71.4% selected opioid analgesic medication while 28.6% selected non-opioid analgesic medication. Contacting the physician for the prescription of opioids was cited as the main delaying process by 43.7% of participants.
Conclusions: The results of the study demonstrated that the nurses had limited knowledge of pain management, because of non-training courses for consequence all of it was associated with poor attitude toward pain management. Most of them did not have formal training in pain management either at the local level. Many of them are familiar with oral route of administration of opioids but still the logistics of administration is not clear to them. Nowadays training and education in pain management is a necessity for medical staff especially for nurses because the adequate knowledge is vital in the provision of quality pain management to patients.


Zimmerman, Bonnie, & McNaron, Toni A. H. (Eds.). 1996. The new lesbian studies: Into the twenty-first century. New York: The Feminist Press at the City University of New York, ISBN 1-55861-136-3, $17.95 paperback, 295 pp. Same sex, Different cultures: Gays and lesbians across cultures. Boulder, CO: Westview Press. ISBN 0-8133-3163-3, $26.00 cloth cover, 204 pp. Caution! These books should be read with an open mind. The material and information contained in these books will make visible the invisible, challenge and deepen your understanding of human sexuality, gender roles, and heterosexism, and bring forth ideas and questions about social and cultural responses to same sex relationships in contemporary and future cultures. While both books address aspects of sexual diversity, they approach the subject matter using conflicting theoretical perspectives and address two different sets of issues in different cultural contexts. Gilbert Herdt (1997), drawing on cultural and historical material, discussed the existence of same sex relationships in a diversity of cultures ranging from Ancient Greece to contemporary societies. Bonnie Zimmerman and Toni McNaron (1996) focused on one specific culture, academia, in their collection of writings that provide a historical and reflective insight into the growth and development of lesbian scholarship. Same sex, different cultures: Gays and lesbians across cultures is divided into seven chapters. In the first chapter, Herdt addresses a few of the more significant problems anthropologists experience in studying sexuality; his theoretical position, and anthropological concepts central to understanding further discussion. Herdt raises two primary challenges to studying sexuality. Anthropologists struggle over how one understands sexual behavior and practices without relating it to one's own sexuality. The second challenge relates to cultures that "simply lack categories or concepts that cover the meanings of the contemporary notion of homosexual" (p. 7). Herdt responds to these problems by approaching this book from a queer theory perspective. Queer theory "argues that history and cultural descriptions are never distinguishable from the authors and assumptions of normality through which subjects or objects are described" (p. 9). In doing so, he challenges the use of all categorical and classification systems and all notions of what is "normal." Queer theorists view concepts such as `sexual identity' and `the body' as "illusions in language and power relationships" (p. 10). Herdt argued that we cannot understand one's sexual lifeway outside of the context of their sexual culture. Herdt stated that "the most important lesson to learn from the cross-- cultural and historical study of homosexuality is that there is room for many at the table of humankind in societies around the world" (p. 27). While there may be room for all at this table of humankind, Herdt suggests that in some countries, the cultural myths associated with homosexuality have contributed to their not being welcomed or invited. In this second chapter, Herdt provides insight into the dominant myths that permeate the United States and other western cultures, revealing the social and historical prerogatives of power from which they have been constructed. Chapter three focuses on the existence of same sex relationships in non-- western cultures. Drawing on ethnographic reports and existent literature, Herdt suggested that these relationships were based on age, gender transformations, and specialized social roles or practices. Age structured homoerotic relationships are reported to be more frequent amongst men than women. It was believed that these relationships contributed to young men's training as warriors (i.e. ancient Greece, feudal Japan); the development of their masculinity (i.e. Australian aboriginals, Sambia) and as responses to cultural taboos and restrictions (i.e. Africa). Gender transformed roles or third gender roles were related to cultural requirements requiring one of the partners to take on the behaviors, role, and dress of the other gender (i. …


In this article, I explore several of Foucault's claims in relation to race, biopolitics, and power in order to illuminate some concerns in the wake of the post-9.11.01 political regime of population management. First, what is the relationship between sovereignty and power? Foucault's writings on the relation between sovereignty and power seem to differ across his writings, such that it is not clear whether he had definitively circumscribed the role of sovereignty in relation to "power." Second, while central sovereign authority, at least in "Society Must Be Defended" has been displaced by Foucault's analysis of power, the question still remains as to what drives or instantiates the exercise of power. I lay out an account of what I will call "ontopolitics," as one that foregrounds the role of sovereign authority in ascribing racial divisions. Moreover, these divisions are driven by cultural, social, and moral criteria that complement—or circumscribe—biopolitics—and are inscribed at the level of the ontological, or onto-ethical.


A recent medical device recall notification from Philips Respironics reported on risk for degradation of polyurethane foam (PUF) in continuous positive airway pressure (CPAP) devices used for obstructive sleep apnoea (OSA) treatment [1]. The degraded foam particles may cause airway irritation, and the volatile gas products (diethylene glycol, toluene di-isocyanate isomers, toluene diamine isomers) released during the degradation process may also have cyto- and genotoxic effects [1]. Kendzerska et al. [2] reported no increase in cancer incidence in 1220 patients using PUF devices over a mean observation time of 7.5 years. However, studies assessing airway symptoms and health outcomes other than cancer are lacking. Airway irritation from degraded foam particles may be particularly harmful for patients with pre-existing obstructive lung disease (OLD). This study aimed to evaluate the association between PUF-CPAP use and adverse health outcomes in OSA patients with/without comorbid OLD. Patients with PUF-CPAP and especially those with pre-existing obstructive lung disease had increased use of anti-obstructive medication but there were no differences in hospitalisations and mortality, and data on cancer were inconclusive https://bit.ly/3uVIzXG


We review the technical challenges associated with the production and use of various coal chars in a direct carbon conversion fuel cell. Existing chemical and physical deashing processes remove material below levels impacting performance at minimal cost. At equilibrium, sulfur entrained is rejected from the melt as COS in the offgas.


This two-part study describes the development and validation of a method for quantifying adolescent personality pathology using the latest edition of the Shedler–Westen Assessment Procedure for Adolescents (SWAP-II-A), an instrument designed to be used by clinically experienced observers. In Study 1, experienced psychologists and psychiatrists described a normative clinical sample of 950 North American patients. Study 2 applied the SWAP-II-A in a day treatment setting. Results indicated that SWAP-II-A personality disorder (PD) scales evidenced high internal consistency, construct validity with Diagnostic and Statistical Manual of Mental Disorders (5th ed.) symptoms and diagnoses, and concurrent validity with Child Behavior Checklist (CBCL) ratings. Independent observers saw patients similarly, and PD assessments were significantly associated with CBCL scale scores and ward behavior.


In this paper we discuss interest rate curve interpolation methods and their properties in the context of financial applications. We review the modern (multi-curve) theory of interest rate curve modeling, taking into account collateralization. Building on this solid foundation we reconsider several curve interpolation methods and derive some modifications thereof. We revise well-known criteria for the goodness of interpolation and introduce the hedge error, arising from dynamic delta-hedging over an extended period, as enhanced evaluation parameter. This new criterion reflects both a practical and meaningful choice since hedging is the essential instrument applied by banks to mitigate interest rate risks. The hedge error particularly represents the amount of money at risk. Numerical results in a multi-curve financial framework are derived by means of a Java-based implementation performed on actual market data.


This paper presents an overview of the problems most commonly encountered in the analysis of natural gas for water vapor content, and provides details on the successful application of the thin film aluminum oxide moisture sensor to this type of measurement. Natural gas, as it comes from the ground, is usually quite warm and saturated with water. If the gas is not quickly treated to remove liquid water as well as water in the vapor phase, numerous problems can result. The problems associated with this saturation are presented in this paper.


We present spatially resolved X-ray observations of the binary T Tauri star system V710 Tau. Using Chandra's Advanced CCD Imaging Spectrometer (ACIS), we imaged this 3.2″ separation binary system, consisting of a classical T Tauri star, V710 Tau N, and a weak-lined T Tauri star, V710 Tau S. The Chandra ACIS-S3 images—obtained in two 9 ks exposures separated by about 3 months (2004 December and 2005 April)—cleanly resolve the V710 Tau binary, demonstrating that both stars emit X-rays, and thereby enabling the first spectral/temporal study of the individual components of this mixed (classical and weak-lined) T Tauri star binary system. The northern component, V710 Tau N, appears to have been in a flaring state during the first (2004 December) exposure. During this flare event, the X-ray flux of the classical T Tauri star hardened significantly. Single-component plasma models with plasma temperatures in the range kTX ∼ 0.7–1.1 keV are adequate to fit the observed X-ray spectra of V710 Tau S in 2004 December and both stars in 2005 April. The 2004 December flare-state observation of V710 Tau N requires a higher temperature plasma component (kTX ∼ 2.5–3.0 keV) in addition to the soft component (kTX ∼ 0.5 keV), and is better fit by a model that includes a slightly enhanced Ne/Fe abundance ratio. These results are generally consistent with statistical contrasts between the X-ray emission properties of classical (rapidly accreting) versus weak-lined (weakly accreting or nonaccreting) T Tauri stars.


There is widespread agreement that the business rates system needs to change – but what are the options for fairer and more efficient commercial property taxation?


ABSTRACT Aim: ICAN study (NCT01106781) was designed to investigate EGFR gene mutation status, clinical outcomes and recurrent risk factors in early stage Chinese NSCLC patients with adenocarcinoma (ADC) histology after complete resection. Methods: Patients were ≥18 years old, with histological diagnosis of NSCLC ADC, and received surgical complete resection. Tumor sample EGFR mutation status was determined according to clinical routine practice. All eligible patients were followed up for 3 years to collect the clinical information and the survival outcomes. Results: Of 568 patients from 26 sites, 313 (55.1%) patients were EGFR mutation positive. The most common mutations were exon19 deletion and exon 21 L858R mutation found in 139 (24.5%) and 128 (22.5%) patients respectively. 4(0.7%) patients were exon19 deletion + exon 21 L858R mutations and 42 (7.4%) patients were with rare mutations. Frequency of EGFR mutation was not correlated to postoperative pathological stage (P = 0.1047). The 3-year DFS was 58.8%. Subgroup analysis found that 65.6% 3y DFS in EGFR mutant patients and 56.8% in wild type patients (P = 0.0347); 63.8% in exon 19 deletion, 67.2% in exon21 L858R mutation, 100% in exon19 deletion + exon 21 L858R mutations and 63.4% in rare mutations (p = 0.5810). There were 50.7% of the patients who received adjuvant therapy, among which 45.4% received chemotherapy, 4.6% received radiotherapy and 1.8% received TKI therapy, respectively. Among EGFR mutant patients, adjuvant therapy correlated significantly to 3-year DFS (P = 0.0024), but was not significant when adjusted for postoperative pathological stage. Female showed a higher 3-year DFS rate than male patients (67.90% vs 55.70%, P = 0.0041). There was statistically significant difference of 3-year DFS among patients with different postoperative pathologic stage (P Conclusions: The overall EGFR mutation positive rate in operable Chinese ADC was 55.1%. 3-year DFS rate was 58.8%. EGFR mutant patients have a favorable 3-year DFS compared with EGFR wild type. Postoperative pathologic stage had a statistically significant association with 3-year DFS, while age, smoking pack-years didn't show statistically significant associations with 3-year DFS. Disclosure: Y. Wu: Recieved speaker fees from AstraZeneca, Roche, Eli Lilly, Sanofi, Pfizer. All other authors have declared no conflicts of interest.


Recently, with the spread of smart device and the introduction of web services, the data is rapidly increasing online, and it is utilized in various fields. In particular, the emergence of social media in the big data field has led to a rapid increase in the amount of unstructured data. In order to extract meaningful information from such unstructured data, interest in big data technology has increased in various fields. Big data is becoming a key resource in many areas. Big data's prospects for the future are positive, but concerns about data breaches and privacy are constantly being addressed. On this subject of big data, where positive and negative views coexist, the research of analyzing people's opinions currently lack. In this study, we compared the changes in peoples perception on big data based on unstructured data collected from the social media using a text mining. As a results, yearly keywords for domestic big data, declining positive opinions, and increasing negative opinions were observed. Based on these results, we could predict the flow of domestic big data.


The electronic structures of the ternary(Hume-Rothery) L2_1-phase compound AlCu_2Ti are calculated by first-principles using full potential linearized augmented plane wave(FLAPW) method with the generalized gradient approximation(GGA).The results show that the total DOS depends strongly on the positions of TM atoms,and the TM d DOS plays a crucial role in hybridization with other element valence electrons.However,the Al 3s states are repelled far away from the Fermi energy,and the Al 3d states are far more extended-like in the character than the d states.Furthermore,the total DOS_s in are modulated by Al 3p states and the Al 3p states are more sensitive than d states to change in the electronic interactions.Especially,the AlCu_2Ti has more particular flat total DOS than the others,and shows the poor metallic character.


Shear banding characterization of Zr64.13Cu15.75Ni10.12Al10 and Zr65Cu15Ni10Al10 BMGs was studied by using Rockwell indention method. Well-developed shear band pattern can be found for both BMGs after indentation. The significant difference in plastic deformation ability can be ascribed to different shear banding features.


Refracturing treatment is an economical way to improve the productivity of poorly or damaged fractured horizontal wells in tight reservoirs. Fracture reorientation and fracture face damage may occur during refracturing treatment. At present, there is still no report on the rate decline solution for refractured horizontal wells in tight reservoirs. In this work, by taking a semi-analytical method, traditional rate decline and Blasingame-type rate decline solutions were derived for a refractured horizontal well intercepted by multiple reorientation fractures with fracture face damage in an anisotropic tight reservoir. The accuracy and reliability of the traditional rate decline solution were verified and validated by comparing it with a classic case in the literature and a numerical simulation case. The effects of fracture reorientation and fracture face damage on the rate decline were investigated in depth. These investigations demonstrate that fracture face damage is not conducive to increasing well productivity during the early flow period and there is an optimal matching relationship between the principal fracture section angle and permeability anisotropy, particularly for the reservoirs with strong permeability anisotropy. The fracture length ratio and fracture spacing have a weak effect on the production rate and cumulative production while the fracture number shows a strong influence on the rate decline. Furthermore, multifactor sensitivity analysis indicates that fracture conductivity has a more sensitive effect on well productivity than fracture face damage, implying the importance of improving fracture conductivity. Finally, a series of Blasingame-type rate decline curves were presented, and type curve fitting and parameter estimations for a field case were conducted too. This work deepens our understanding of the production performance of refractured horizontal wells, which helps to identify reorientation fracture properties and evaluate post-fracturing performance.


The variational equations and the evolution matrix are introduced and used to discuss the stability of a bound Hamiltonian trajectory. Singular-value decomposition is applied to the evolution matrix. Singular values and Lyapunov exponents are defined and their properties described. The singular-value expansion of the phase-space velocity is derived. Singular values and Lyapunov exponents are used to characterize the stability behaviour of five simple systems, namely, the nonlinear oscillator with cubic anharmonicity, the quasi-periodic Mathieu equation, the Henon-Heiles model, the 4+2 linear chain with cubic anharmonicity, and an integrable system of arbitrary order.


The field dependent magnetization of single crystal Ti2O3 doped with 2% and 5% vandaium was measured down to 1.6K. The results disagree with the predicted magnetic behavior based on the VanZandt impurity level model proposed for this system.


The abrupt fracture of vibrating screen lower beam will make the whole coal preparation product line shutting down and result in large economic losses. In this paper, according to the difficulties and requirements of vibrating screen lower beam crack detection, a quick detection method was put forward based on combined technical method of metal magnetic memory testing and eddy current testing. The experimentation and spot application results showed that the method was efficient, and could achieved the early crack fault quick detection of vibrating screen lower beam. Its application could decrease even avoid the lower beam abrupt fracture occurrence of the vibrating screen, and bring enormous economic and social effects.


Information regarding taxation of Health Libraries Inc. is provided. The Australian Taxation Office publishes ClubPack which is a taxation guide for clubs, societies and associations and Guide to register for the new taxation system.


This paper expounds the equipment transformation of comprehensive mechanized coal mining face in Chengzhuang Coal Mine, including the transformation of the tail of the extensible conveyer, the updating and transformation of gate equipment and the updating of gate belt conveyer.