Presents a conceptual framework that can help focus treatment of the contrasts between global and local behavior on the one hand and between continuous and discontinuous behavior on the other. Since that framework describes different perceptions of regulation and stability behavior, it provides the necessary background for a 2nd topic, which concerns the particular causative relations and processes within ecosystems, the influence of external variation on them and their dynamic behavior in time and space. A 3rd topic synthesizes present understanding of the structure and behavior of ecosystems in a way that has considerable generality and organizational power. A 4th connects that understanding to global phenomena on the one hand and local perception and action on the other.


BRICS is one of the alternative projects of multipolar world building. BRICS was created as community of the most powerful developing countries seeking to reform the world order. What is unique about this bloc is the fact that it includes counties with various social-economic models and cultural-civilizational characteristics. BRICS is primarily a dialogue platform for discussing major international issues. At the same time the foreign policy of BRICS is based on the solid basis of economic and military-political potential of the member states. BRICS offers new ways of reforming the system of international regulation.


The concept of a balanced near semiring was introduced by the authors in [5] in order to describe ring-like structures derived by means of lattices with involution, in particular with complementation. Now we show that every such balanced near semiring has an underlying structure which is a Boolean algebra. Based on this result, we describe ideals of these near semirings. A natural one-to-one correspondence between ideals and congruences is established. 2010 Mathematics Subject Classification: 16Y60; 16Y30; 06E25


An image sensor and a fabrication method of the same are provided to improve a defocusing effect caused by a step of a boundary between a pixel part and a peripheral part. A pixel part and a peripheral part are defined on a semiconductor substrate. A pixel array(110) is formed on the pixel part. A PMD(Pre-Metal Dielectric) layer(120) is formed on the semiconductor layer. An IMD(Inter-Metal Dielectric) layer(130,140,150) is formed on the PMD layer. The IMD layer positioned on an upper surface of the pixel array is etched as much as the first depth in comparison with an upper surface of the peripheral part. A color filter array(160) is formed on the etched IMD layer. A micro-lens array(190) is formed on the color filter array. The micro-lens array has continuous curves without a gap between adjacent lenses.


The empirical analysis of this article presents an interpretation of religious attitudes expressed during the COVID-19 pandemic in the Muslim communities in Moluccas, Indonesia. The article explains religious experiences and the meanings of their resistance to COVID-19. Various measures to respond to the pandemic have created resistance in religious communities globally. As a result, there have been violations of health protocols, including in Indonesia. Data were obtained through interviews and observations around Ambon City, Moluccas, Indonesia. The data were analyzed through qualitative methods and constructivist paradigms based on a phenomenological perspective, especially a social constructionist perspective. This article explains the role that phenomenological and religious studies of resistance can play in understanding effective public health management and improving the government's policies and the pandemic health protocols. Subjective experiences occurred in religious worship, community homes, educational institutions, and rituals amid uncertain information and political polarization. The results indicate that resistance encompasses planning, fraud, global disasters, negative labeling, panic, anxiety, and fear. Resistance will have an impact and become necessary due to the involvement of individuals; this affects daily life for religious belief and coping with fear, panic, and uncertainty of COVID-19. This article will benefit Muslim communities' subjective experiences regarding resistance during the COVID-19 pandemic and encourage further research.

http://www.pertanika.upm.edu.my/resources/files/Pertanika PAPERS/JSSH Vol. 30 (4) Dec. 2022/27 JSSH-8473-2021.pdf


In this paper, we aim to develop a travelogue service to discover and convey various travelogue digests, in form of theme locations and geographical scope to their readers. In this service, theme locations in a travelogue are the core information to discover. Due to the inherent ambiguity of location relevance, we explore the textual (e.g., surrounding words) and geographical (e.g., geographical relationship among locations) features of locations to perform location relevance classification for theme location discovery. Finally, we conduct comprehensive experiments on collected travelogues to evaluate the performance of our location relevance classification technique and demonstrate the effectiveness of the travelogue service.


Purpose – The aim of the investigation is to identify enabling and disenabling factors in the development and operation of virtual teams; to evaluate the importance of factors such as team development, cross‐cultural variables, leadership, communication and social cohesion as contributors to virtual team effectiveness.Design/methodology/approach – A total of 115 employees in virtual teams using an on‐line survey contributed a 55 per cent response rate. An on‐line survey combining both quantitative Likert scale and qualitative explanatory questions measured the following variables in addition to those above: team member roles and responsibilities, relationships and trust and team dynamics.Findings – Results indicated that cross‐cultural communication improvement, managerial and leadership communication, goal and role clarification, and relationship building are most important to virtual team performance.Research limitations/implications – Further research focusing on particular sectors such as knowledge‐ i...


This paper seeks to understand the intriguing but o nly sparsely explored phenomenon of "leisure time invention," where the main underlying idea for the new product or process occurred when the inventor was away from the workplace. We add to previous res earch by focussing on the inventive creativity of the individual researcher, and reassessing the imag e of researchers inventing during unpaid time – who have often been dispatched as "hobbyists". Based on the responses from a survey of 3,000 German inventors, we test hypotheses on the conditions und er which leisure time invention is likely to arise, and how valuable it is. We find that the incidence of leisure time invention is positively related to high workplace inventive productivity, and exposure to a variety of knowledge inputs. Leisure time inventions are more frequently observed in conceptu al-based technologies than science-based technologies, and in smaller R&D projects. The aver g value of leisure time inventions exceeds the value of work time inventions.


. Some symmetries for Casorati determinants whose entries are q classical orthogonal polynomials are studied. Special attention is paid to the symmetry involving Big q -Jacobi polynomials. Some limiting situations, for other related q -classical orthogonal polynomial families in the q -Askey scheme, namely q -Meixner, q -Charlier, and q -Laguerre polynomials, are considered.


This study aims to adapt and validate the Bulgarian version of the Social and Emotional Loneliness Scale on adults and older adults. We present the results of the psychometric assessment of the questionnaire on a sample of adults aged 35—75 (N=332; Mage=49.45; SD=11.17). Exploratory factor analysis revealed four factors: two factors were identical to the first two sub-scales, the third sub-scale split into two separate factors. Reliability of the new sub-scales was assessed with Cronbach's α coefficient that showed high levels of reliability for the general scale (α=0.875) and for all four sub-scales (α ranged from 0.843 to 0.873). Confirmatory factor analysis proved the four-factor structure of the adapted scale. The convergent validity of the Social and Emotional Loneliness Scale was proved by correlation analysis with the Differential Questionnaire of Loneliness Experience. Our study yielded the adequate psychometric characteristics of the Social and Emotional Loneliness Scale for adults and older adults in Russia. In future research, we plan to increase the sample to standardize the scores for the scales.


OBJECTIVE: To study the relationship between the serum concentrations of soluble E-selectin and intercellular adhesion molecule-1 and metastasis of colorectal cancer. METHODS: The serum concentrations of soluble E-selectin and intercellular adhesion molecule-1 were determined in 64 cases of colorectal cancer by using the immunohistochemistry technique. In addition. carcinoembryonic antigen (CEA) was also determined. RESULTS: sE-selectin levels and sICAM-1 levels were significantly increased in patients with colorectal cancer. P=0.001 and P=0.032, and sE-selectin levels and sICAM-1 levels were significantly higher in patients with distant metastasis than those in ones without, P=0.004 and P=0.015. Serum concentration of sE-selectin and sICAM-1 were correlated with CEA levels, P=0.025 and P=0.038. CONCLUSION: Increased sICAM-1 serum levels and sE-selectin levels may reflect the widespread of the disease and contribute to the progression of colorectal cancer.


Abstract The importance of pivoting is well established in the context of nonparametric confidence regions. It ensures enhanced coverage accuracy. However, pivoting for directional data cannot be achieved simply by rescaling. A somewhat cumbersome pivotal method, which involves passing first into a space of higher dimension, has been developed by Fisher and Hall for samples of unit vectors. Although that method has some advantages over nonpivotal techniques, it does suffer from certain drawbacks—in particular, the operation of passing to a higher dimension. Here we suggest alternative pivotal approaches, the implementation of which does not require us to increase the intrinsic dimension of the data and which in practice seem to achieve greater coverage accuracy. These methods are of two types: new pivotal bootstrap techniques and techniques that exploit the "implicit pivotalness" of the empirical likelihood algorithm. Unlike the method proposed by Fisher and Hall, these methods are also applicable to axia...


Rice germplasm of Chhattisgarh plays an important role in preserving and maintaining the biodiversity of rice. Rice germplasm is a very important asset that must be preserved. There is a strong need not only to conserve landrace genotypes but also broaden the genepool of rice for the future utilization in breeding of high yielding, superior quality and better adapted varieties in the country. In crop improvement programme, to increase the productivity breeder needs to maintain a pool of diverse desirable donor parents (Joshi et al., 2013). Genetic diversity plays a key role in selecting the suitable parents for hybridization programme resulting in superior hybrids and desirable transgressive segregants (Rathi et International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 11 (2019) Journal homepage: http://www.ijcmas.com


The issuing of performance bonds or construction guarantees in terms of a building contract may hold important consequences for the parties to a construction guarantee. Recently construction guarantees have received much attention from our courts and some of these cases even proceeding to the Supreme Court of Appeal (Loomcraft Fabrics CC v Nedbank Ltd 1996 (1) SA 812 (A); Lombard Insurance Company Ltd v Landmark Holdings (Pty) Ltd 2010 (2) SA 86 (SCA); Dormell Properties 282 CC v Renasa Insurance Co Ltd 2011 (1) SA 70 (SCA); Minister of Transport and Public Works, Western Cape v Zanbuild Construction (Pty) Ltd 2011 (5) SA 528 (SCA); Casey v FirstRand Bank Ltd 2014 (2) SA 374 (SCA); FirstRand Bank Ltd v Brera Investments CC 2013 (5) SA 556 (SCA); and Guardrisk Insurance Company Ltd v Kentz (Pty) Ltd (92/2013) [2013] ZASCA 182). There may be various reasons for this sudden escalation in litigation with construction guarantees as the subject matter. One of the reasons may be due to numerous major construction projects that have been undertaken in the last few years in South Africa. Notable examples of these major construction projects include the building of stadia for the 2010 FIFA Soccer World Cup, the Gautrian Project, and the Gauteng Freeway Improvement Project.


Augmented orthogonal arrays (AOAs) were introduced by Stinson, who showed the equivalence between ideal ramp schemes and AOAs (Discrete Math. 341 (2018), 299–307). In this paper, we show that there is an AOA ( s , t , k , v ) if and only if there is an OA ( t , k , v ) which can be partitioned into v t − s subarrays, each being an OA ( s , k , v ) , and that there is a linear AOA ( s , t , k , q ) if and only if there is a linear maximum distance separable (MDS) code of length k and dimension t over F q , which contains a linear MDS subcode of length k and dimension s over F q . Some constructions for AOAs and some new infinite classes of AOAs are also given.


Review(s) of: Our greatest challenge: Aboriginal children and human rights, by Hannah McGlade, 284 pp, Aboriginal Studies Press, Canberra, 2012, ISBN 9781922059109 (pbk), $39.95.


The low-field quantum Hall effect is investigated on a two-dimensional electron system in an AlGaAs/GaAs heterostructure. Magneto-oscillations following the semiclassical Shubnikov-de Haas formula are observed even when the emergence of the mobility gap shows the importance of quantum localization effects. Moreover, the Lifshitz-Kosevich formula can survive as the oscillating amplitude becomes large enough for the deviation to the Dingle factor. The crossover from the semiclassical transport to the description of quantum diffusion is discussed. From our study, the difference between the mobility and cyclotron gaps indicates that some electron states away from the Landau-band tails can be responsible for the semiclassical behaviors under low-field Landau quantization.


At present,it is difficult to be fair,reasonable and comprehensive in highway engineering evaluating process.Considering the problem,the author put forward evaluation method by applying the order relation analysis.Based on practical conditions of a project,the weight order of bidding documents is calculated by using order relation analysis,then the optimal bidding is determined scientifically.The results show that the evaluation method has merit of convenient calculation and operable authenticity.


Abstract Objectives Vitamin K and metabolites have a beneficial role in blood coagulation, bone metabolism and growth. However, the determination of vitamin K concentrations in the blood in patients consuming a diet with naturally occurring vitamin K is currently challenging. We aim to develop a cost-effective and rapid method to measure vitamin K metabolites with potential application for clinics and research. Methods We developed a simple liquid chromatography-tandem mass spectrometric (LC-MS/MS) method for the determination of vitamin K1, menaquinone-4 (MK-4), menaquinone-7 (MK-7) and vitamin K1-2,3 epoxide in human serum and validated the method in a study cohort of 162 patients tested for carbohydrate malabsorption and in 20 patients with oral phenprocoumon intake. Results The overall precision (CVs) ranged between 4.8 and 17.7% in the specified working range (0.06–9.0 nmol/L for all analytes except for MK-7 with 0.04–6.16 nmol/L). In the malabsorption cohort samples, measured values were obtained for all different vitamin K metabolites except for vitamin K1-2,3 epoxide. This metabolite could be detected only in patients with phenprocoumon intake. The good performance of the method is especially achieved by the interaction of three factors: the use of lipase in the sample preparation, the use of an atypical fluorinated reversed phase column, and a logarithmic methanol gradient. Conclusions The described method is able to determine the concentration of four vitamin K metabolites in a time-efficient, simple and cost-effective manner. It can be suitable for both routine clinics and research.


WAHYU NURKHAENI. Natural regeneration potential Shorea leprosula Miq. in Gunung Dahu Forest Research, Leuwiliang, Bogor District, Supervised by PRIJANTO PAMOENGKAS and HENTI HENDALASTUTI RACHMAT. The establishment of man-made forest is an ex-situ conservation effort. Sustainable plantation management, one of the indicators is the creation of natural regeneration characterized by natural regeneration and diversity of species. Gunung Dahu a man-made Dipterocarpaceae Forest Research is one form of plantation development that has natural regeneration potential. This research aimed to identify the regeneration potential of S. leprosula and environmental factors that affect the regeneration of S. leprosula in the Gunung Dahu Forest Research. The study showed that natural regeneration in plot 2 and plot 5 has the highest number with canopy openness of 20%  25%. Altitude of place does not support natural regeneration of Shorea leprosula. Natural regeneration of seedling stage were abundant while saplings only detected in very few numbers.


For improving the reliability of the output drive unit of the reactor protection system in Qinshan NPP, the former design of this part was improved and researched on the problem appeared during the commissioning and operation under the conditions of narrow process space of cabinets and unchanged overall arrangement : (1) The output relay modules was redesigned to unify the relay specification to improve the versatility, and also to improve the pin's contact by means of welding them directly on the printed circuit boards and to make the modules detachable by connectors instead of previously non-detachable. The modules were connected in series by both power supply line and ground line which were finally conneted at same point respectively, so that other protection signals can still be output correctly when a single module is removed. (2) The relay drive circuit was also redesigned for working in on-off state instead of in amplification to minimize the power consumption. In the other hand, the CMOS buffers were taken to couple the CMOS circuits to the TTL circuits. The actuating time for the new shutdown relay was decreased from the former 35 ms to 5 ms, the actuating time for the engineered safety feature drive signal relay was decreased from 10 ms to 6 ms after the above-mentioned improvements , the reliability of the RPS is remarkably improved and a great economic benefit is obtained.


Bandwidth balancing is a procedure that gradually achieves a fair allocation of bandwidth among simultaneous file transfers on a distributed-queue dual-bus (DQDB) network. Bandwidth balancing was originally designed for traffic of a single priority level. Three ways are demonstrated to extend this procedure to multi-priority traffic.<<ETX>>


Abstract:  A new genus and species of omomyid primate, Melaneremia bryanti, is described from the Early Eocene Blackheath Beds of Abbey Wood, London, UK. It shares unique derived characters with the European subfamily Microchoerinae and is its most primitive member. It is nevertheless more derived than the primitive omomyid Teilhardina belgica from the beginning of the European Eocene. Cladistic analysis shows that the Microchoerinae are sister group to a clade comprising subfamilies Omomyinae and Anaptomorphinae, but excluding Teilhardina belgica and T. asiatica, which are stem omomyids. The Mammalian Dispersal Event (MDE), which marks the beginning of the Eocene (55·8 Ma), saw the dispersal of primates, perissodactyls and artiodactyls into the Northern Hemisphere. At this time similar species of Teilhardina lived in Europe, Asia and North America. The Abbey Wood microchoerine lived about 1 million years later. It co‐occurs with non‐primate species identical or very similar to those that lived in North America. The latter were ground‐dwellers, whereas the microchoerine and others that show distinct differences from North American relatives were tree‐dwellers. Land‐bridges connected North America and Europe via Greenland at the beginning of the Eocene, but 2 million years later these had been severed by submarine rifting. North American species at Abbey Wood indicate that a land connection still remained at c. 55 Ma. However, the forest belt that must have been continuous during the MDE to allow tree‐dwellers to disperse between the continents is likely by this time to have been disrupted, perhaps by volcanic eruption.


This research examines the depiction of normative women in the Edo period (1603-1868) in the novel entitled Hanaoka Seishu no Tsuma (1966) by Ariyoshi Sawako, a Japanese female writer in the post World War II Showa era. Reflecting on the novel's normative female characters, it analyzes the silenced voices of women. It will contribute to the discussion on how the normative female figures criticizing the patriarchal hegemony that has not been revealed in the literary canon of the Edo period. This research shows how normative women characters are presented in the text as a feminine strategy to criticize this hegemony. The researchers use feminist criticism theory from Butler's gender performativity (1990). The study concludes that although normative women characters are commonly represented as men dominating women, those can also be used to criticize the patriarchal hegemony.


This paper introduces the means and characteristics of signal acquisition of the non-contact life parameters detection system as well as the design of preprocessor circuit.The results show that the preprocessor is designed reasonably,which can provide the computer with high quality signals.


Curcuma species contain turmerin, essential oils and curcuminoids. Curcumin has been shown to possess a wide range of pharmacological activities including anti-inflammatory, anticancer, antioxidant, wound healing, hypoglycemic, anticoagulant, antifertility and antimicrobial. Preparation of extract from Curcuma species samples viz. C. longa, C. longa var. lakdong and C. aromatica, collected from different places of Meghalaya was done by stirring and stationary extraction technique. TLC was performed to confirm the presence of active components in the extract with reference to the powdered sample. Separation of the fractions was done by silica gel column chromatography. The presence of active components in different fractions was estimated by measuring absorbance in the UV and Visible range. A variation in the curcuminoid content was observed among the samples studied and a high percentage was observed in C. longa var. lakdong. In the present study, the existence of variation in curcuminoid content of Curcuma species of Meghalaya was established. The findings can help in selecting and multiplying those Curcuma cultivars having curcumimoid content and also extracting curcumin on a commercial scale.


MWD (Measurement while drilling) system for geothermal wells has been developed by NEDO (the New Energy and Industrial Technology Development Organization) since 1991. As a part of this system, the drilling support system has been also developed. The well trajectory prediction system is one of this drilling support system including the well trajectory planning system, the well trajectory visualization system, the temperature analysis system and so on, and this system will be used for prediction of well trajectory while drilling and for design of BHA (bottom hole assembly) before drilling. We discussed about the theory of the well trajectory prediction system and its case studies in this paper.


Embryogenic cell suspensions (ECS) of 'Grande Naine' (Musa AAA group) were plated on RD1 or M3 medium for the regeneration of somatic embryos, 1 to 2 weeks after last subculture. The first regenerable somatic embryos were observed about 3 weeks after inoculation. After 8 weeks of culture, the mass of the embryogenic mass increased about 5 to 18 times and the number of somatic embryos that could be regenerated from 1 mL settled cell volume (SCV) of ECS ranged between 0.71×10~5 and 3.07×10~5, depending on pre-culture time in liquid medium before regeneration, regeneration media and incubation conditions (light/dark). The frequency of plant recovery and the amount of plantlets regenerated from 1 mL SCV of ECS were indirectly affected by somatic embryos regeneration conditions that were studied.


In order to propel a manned space craft from earth orbit to Mars various propulsion systems are considered. Propulsion systems which are discussed in connection with manned Mars flight are: chemical rockets, nuclear thermal rockets, ion engines, thermal arc jet thrusters, magnetoplasmadynamic (MPD) thrusters. High power thermal arc jet thrusters and continuously running self-field MPD thrusters offer the capability of being operated at different power levels. This results in variable specific impulse that mainly depends on propellant mass flow rate and electrical power. For each thruster design the attainable specific impulse is limited by a maximum arc current, which can be supplied to this thruster. Therefore, this paper deals with a new thermal plasma thruster which uses two different mechanisms to couple energy into the propellant. ATTILA [8] combines the advantages of thermal arc jets and self-field MPD thrusters, especially their relatively simple setup, and the reliability of a radio frequency power supply, which is usually used for surface hardening. This paper describes the setup of ATTILA and shows its utility as propulsion system. Additionally, numerical calculations to optimize future thruster configurations will be presented.


Through questionnaires and other forms to investigate the understanding of science and engineering students on Chinese medicine culture, and through the combination of traditional media and modern new media to enhance their own Chinese medicine cultural literacy and improve the influence of Chinese medicine.


Locating the Proper Authorities: The Interaction of Domestic and International Institutions. Edited by Daniel W. Drezner. Ann Arbor: University of Michigan Press, 2002. 240 pp., $52.50 (ISBN: 0-472-11289-9).

Within international relations, interest in the interplay between international and domestic politics dates from at least the 1960s and the development of "across-systems-theory" (Rosenau 1969; Wilkenfield 1973). However, it has only been in the past fifteen years that the field of international relations has placed any real emphasis on including domestic factors in its explanations of international behavior. In the past decade, for example, constructivists have advocated the importance of agents as well as structure in explaining politics, redirecting attention away from purely structural explanations of international politics and opening the door for the analysis of the interaction between the international system and substate actors (Koslowski and Kratochwil 1994; Kubalkova, Onuf, and Kowert 1998; Ruggie 1998). Foreign policy analysts, similarly, have asserted a need to account for both international and domestic politics when explaining the actions of decision makers (Holsti and Rosenau 1988; Karvonen and Sundelius 1990; Anderson, Hermann, and Hermann 1992; Carlsnaes 1992; Hagan 1994; Foyle 1997).

To a large degree, this heightened interest in the interaction between domestic and international factors dates from the publication of Robert Putnam's (1988) article "Diplomacy and Domestic Politics: The Logic of Two-Level Games." Putnam argued that the outcomes of international negotiations are determined by decision makers' efforts to reconcile the competing political demands of the international arena and critical domestic constituents. Specifically, the ability to reach an agreement with another state is contingent on a leader's ability to craft a proposal that is not only acceptable to the opposing government but can also be ratified domestically. Although very simple in design, Putnam's model is powerful in that it provides a way to link activities at the international and domestic levels and to account for their interaction. Putnam's work inspired further research on the …


Presently breast cancer detection is a very important role for world young women to save and extended to the life. The new proposed technology is anisotropic median diffusion filter for denoising low-signal-to-noise molecular images. This filter, which incorporates a median filter into the diffusion steps, is called an anisotropic median-diffusion filter. This hybrid filter achieved much better noise suppression and reduced gausssian noise, spikes compared with the anisotropic diffusion filter when it was tested on an image created based on a molecular image model. We prepare a algorithm detect of Brest Cancer early with molecular imaging ADME uses to the (i.e) uses of density of molecular in this study we develop a mathematical mode for ADME and together the breast cancer molecular image and analysis that performance .The anisotropic median-diffusion filter also achieved good smoothen in inner area and outer area boundry of the molecular images. In this filter particularly useful for non linear molecular images.


One of alternative ways to maintain valuable genetic material is to develop optimal conditions for cultivation in an in vitro system. The goal was to evaluate the condition of plants based on changes in the shoot length indicator in order to explore the maintaining mode of the collection. We took the experimental samples from the "Vegetating collection of plants in vitro of promising varieties and clones of grapes": 13 local Crimean varieties and 9 varieties of the Institute Magarach selection. Plant containing culture bottles were in the cold storage without internal lighting at 10-12°C for 6 months. The cultivation findings demonstrated that grape varieties differed in viability and intensity of morphogenesis. Moreover, after storage, they had a high regenerating ability of the buds.


The influence of speech sounds on the unconscious perception of the semantic load of speech is found out. The effect of the phonetic composition of speech on the emotional state of a person was studied. We developed a web-based application that determines the unconscious emotional reactions of a person to speech (or color) impact.


. Today's student youth is a supporter of democratic changes and, consequently, of democratic values. However, the contradictory nature of modern values and the student community diversity necessitate the strengthening of purposeful influence on their awareness, which should be fulfilled in the context of freedom as a universal factor in personal development. The purpose of our study is the necessity to form democratic values of student youth and the priority ways of this process in the context of educational activities as part of the success of training in higher education institutions. Special attention should be paid to such priorities of medical university students, which are established not only at the semantic, organizational, functional, communicative levels of the educational process, but also through macro- and mi-croenvironment, mass media, Internet technologies, as well as extracurricular activities of higher educational institutions, which includes the activities of student youth in self-government organizations, clubs, volunteering. Democratic values embody the importance of democracy as a worldview ideal, its attractiveness to most people, the reason why democracy is worth defending, making it an element of the political consciousness of millions of citizens and gaining new supporters around the world. Core values above-mentioned values and the development of educational activities. It is especially relevant to involve broad sections of the population – parents, teachers, government officials – to main democracy ideas understanding: freedom and responsibility, human rights and the ability to defend them, the involvement of every citizen in social processes, and social justice. Education is a process on which the future of the nation depends. In addition, a well-planned educational process is a necessary condition for its quality, which involves teachers, educational technologies, methods, tools (visual aids, textbooks, technical devices, etc.), educational management. The higher medical institution provides general cultural and professionally oriented students' training, determines the amount of special knowledge, skills, and abilities sufficient to solve typical tasks of a doctor, including the ability to use theoretical knowledge and practical skills, provide medical care, and assess the impact of disease development factors. Of particular importance in this process are the extracurricular activities in higher education institutions, which include youth work in student organizations: student parliament, student union, student scientific society, society of young scientists, European Medical Student Association, Dental Students Association. Such organizations contribute to the readiness of future specialists to work in modern conditions, their sociali-zation, development, democratic values.


The timing of articulatory gestures in speech production was studied in three speakers. Each speaker recorded a list of 400 sentences comprised of a randomized arrangement of 4 sentences by 5 emphatic stress conditions in which each sentence‐emphatic stress combination was repeated 20 times, One sentence was designated as the target utterance, and the remaining three sentences were included as dummy utterances. Subjects were trained to place emphatic stress on a given content word in each utterance or to produce sentences with normal lexical stress patterns. Spectrograms of each target utterance‐emphatic stress combination were prepared and analyzed according to a time normalization procedure in which the time of occurrence of predetermined events in the articulatory sequence was referred to the normalized utterance duration. The hypothesis tested in this investigation—as predicated by Martin's [Psych. Rev. 79, 487–509 (1972)] theory of timing in speech production—was that the repetition variance associat...


X‐linked adrenal hypoplasia congenita (AHC) is caused by mutations in the NR0B1 gene. This gene encodes an orphan member of the nuclear receptor superfamily, DAX1. Ongoing efforts in our laboratory have identified nine novel NR0B1 mutations in X‐linked AHC patients (Y81X, 343delG, 457delT, 629delG, L295P, 926‐927delTG, 1130delA, 1141‐1155del15, and E428X). Two additional families segregate previously identified NR0B1 mutations (501delA and R425T). Sequence analysis of the mitochondrial D‐loop indicates that the 501delA family is unrelated through matrilineal descent to our previously analyzed 501delA family. © 2001 Wiley‐Liss, Inc.


A 76-year-old woman was admitted to the emergency department with a squeezing severe chest pain starting at rest, 1h before. Previous medical history was unremarkable. An electrocardiogram showed rapidly evolving ST-segment changes ( Panels A–C ). The rapid troponin I assay was positive (1.4 ng/mL). Unknown renal dysfunction was also noted (creatinine of 1.7 mg/dL). Apical akinesia was present on bedside echocardiogram (TEE). Urgent coronary angiography due to unremitting chest pain and hypotension excluded obstructive coronary disease. Ventriculography showed a striking pattern of apical akinesia ( Panels D and E …


Background Electromagnetic �elds have been administered, with mixed success, in order to treat a variety of ailments. During the update of magnetic stimulation technology, modelling studies play an important role. To numerically investigate the possibility of cervical thoracic sympathetic nerve magnetic stimulation with current commercial gure-eight coil commonly used in the implementation of Transcranial magnetic stimulation, and improve coil design specially for cervical thoracic sympathetic nerve magnetic stimulation, we conducted this modelling study. Results We simulated the induced currents and induced electric �elds at the cervicothoracic sympathetic and spinal nerves under different simulation study settings; compared and displayed the induced electric �eld distribution and induced currents at the level of the cervicothoracic sympathetic ganglia (stellate ganglia) At the same time, we recorded the speci�c values of the maximum induced current density of the cervical and thoracic sympathetic nerves and spinal nerves and compared them.


The spermathecae of 22 honey bee queens (virgin and inseminated) were examined in an electron microscope. The epithelium, uniform in cell type and in organellae, lies between the endocuticula and a several layered basal stratum. The endocuticula also is composed of a number of lamellae and contains osmiophilic granula. The epithelial surface and basal region are structured by numerous membrane invaginations, these being more distinct with inseminated and laying queens. The cytoplasm is densily packed with mitochondria. Large and desintegrated types are especially frequent in inseminated, and laying queens; in these a narrow contact exists between the mitochondria - mainly of oblong shape - and the basal membrane infoldings. GOLGI apparatus and ER are only slightly developed. Osmiophilic bodies are found and here discussed as various types of secundary lysosomes or microbodies. Apical and basal membrane invaginations, density of mitochondria and abundance of secundary lysosomes are particularly conspicuous in the epithelium of inseminated and laying queens. Together with the absence of a distinct GERL they indicate a transport function of the spermathecal epithelial cells. It is postulated by the function of the organ and by severing experiments, that a transport occurs through the wall of the spermatheca to maintain the metabolism of the stored sperma-tozoa. This is strongly supported by the results of this first analysis of the fine structure. jungen unbegatteten und 16 ein bis zwölf Monate alten, begatteten oder besamten Bienenköniginnen * wurden entnommen und unmittelbar darauf nach KARNOVSKY (1965), in einer Modifikation von MILLER u. HERZOG (1969) fixiert (2% Formaldehyd, 2,5 % Glutaraldehyd, 0,025 % CaCl2, 0,09 M Cacodylat-Pufler, 7 % Sucrose ; 2 Std.). Die Nachfixation und Nachkontrastierung des Materials erfolgte in 1 °,ö iger Osmiumsäure (Acetat- Veronal-Putier, 0,05 M, 4 % Sucrose, pH 7,4; 1-2 Std.), 0,5 % Uranylacetat und 1 %iger Phosphorwolframsäure. Entwässerung in Alkohol, Einbettung in Styrol-Methacrylat. Herstel- lung der Dünnschnitte mit LKB-Ultrotom, Mikroaufnahmen mit dem EM 9a Zeiss (sachzu-wendung der Stiftung Volkswagenwk). Zum zytochemischen Nachweis der sauren und aikals- chen Phosphatase sowie der Peroxidase wurden die Gomori-Methode nach BARKA u. ANDERSON (1963) und die Methode nach GRAHAM u. KARNOVSKY (1966) in einer Modifikation von MILLER u. HEnzoc (1969) benutzt.


But Professor Mantle Hood maintains that the Pelog tuning has an elastic quality, whereby intervals may be stretched or compressed, so that to speak of a fixed standard tuning is not in accord with the actual situation. Indeed Kunst himself (1949:251-2) states that "The gamelans of the Principalities are classed into different species both according to their absolute pitch and according to the mutual relation between the intervals." In the case of pitch the Javanese, he says, recognise three classes-low, medium and high: the distinction 'according to intervals "lies chiefly in the interval . . . bemgulu." The question therefore arises whether Kunst's averages were too facile a summary of his tunings and whether the latter have not more to tell us about the nature of the Pelog scale. Our concern is not primarily with the pitch of the notes but with the interval-relationships of the notes in an octave. The stretching of the scale by tuning the octaves sharp is a separate issue which lies outside our immediate investigation. In order to gain a clear picture of comparative tunings, the charting of cents intervals is not the best way: it is far better to use what we have called 'Cumulative Cents' figures. In this method we select one note-and we shall choose the note Pelog-and call it 'O': we than progressively add the intervals below it and above it, and assign the totals to the respective notes. Thus Kunst's normalised Pelog in Cumulative Cents, when Pelog is 'O', will be:


Assuming nonlinear tube characteristics, this paper presents: 1) a single mathematical analysis of instantaneous relations applicable to all classes of operation of push-pull audio vacuum tube amplifiers; 2) a mathematical derivation, applicable to all classes of operation, of the composite load line equation and a study of the amplifier frequency response both at medium and low frequencies, with third and higher odd-order effects neglected at low frequencies; 3) an analytical method for finding the maximum magnitude of class AB 1 and AB 2 grid bias beyond which appreciable non-linear distortion occurs; and 4) a single general condition for matching the load to the tubes irrespective of the class of operation, and the interpretation of this condition for each case.


Objective To investigate the effectiveness of 1320 nm Nd:YAG laser in wrinkle reduction of face and neck in Asians. Methods 65 patients were included in the study:all patients received treatment for five to six treatment sessions,alternation were three to four weeks. and the degree of improvement was objectively assessed by the use of clinical photographs by the patients and the doctors. Results Of 65 cases, 55cases were satisfactory with the treatment, the total effective rate was 100%. Conclusion the 1320 nm Nd:YAG laser is a kind of non-albative skin rejuvenation lasers,and has been proven to be effective and safe for wrinkle reduction in face and neck.


The effects of a compatibilizer, namely, an acrylonitrile–butadiene–styrene copolymer (ABS) grafted with maleic anhydrade (MAH) (ABS-g-MAH), on the mechanical properties and morphology of an ABS/polycarbonate (PC) alloy were studied The results showed that a small quantity of ABS-g-MAH has a very good influence on the notched Izod impact strength of the ABS/PC alloy without compromising other properties such as the tensile strength, flexural strength, and Vicat softening temperature (VST). The impact strength of the ABS/PC alloy, to a great extent, depends on the loading of ABS-g-MAH and the degree of grafting (DG) of MAH in the ABS-g-MAH. DSC analysis and SEM observation confirmed that ABS-g-MAH could significantly improve the compatibility of the ABS/PC alloy. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 81: 831–836, 2001


Aims  Smoking contributes to the development of diabetes and diabetes‐related complications. Currently, data on smoking prevalence in subjects with diabetes in Germany are lacking. The aim of our analysis was to determine smoking prevalence in adults with Type 2 diabetes mellitus using data from the two population‐based studies in Germany.


The feasibility study of the Renovation of the Medan City Exemplary Stadium is to obtain a Foundation of the Planning and Design Program regarding the Renovation of the Exemplary Stadium in the City of Medan that meets the community's need for football as a nationally viable sports facility. The Feasibility Study of the Medan City Exemplary Stadium uses quantitative descriptive research, while the data used are primary data and secondary data. The Feasibility Study Method of Exemplary Stadium Renovation Planning to explain the design requirements (design needs) and design determinants related to the planning and design of the Exemplary Football Stadium. The analysis carried out is the physical analysis of the Medan Exemplary Stadium. As a result of the feasibility study of the renovation of the Teladan Medan Stadium, the physical condition of the Teladan Medan Stadium, the existing facilities, and infrastructure have been damaged and some are no longer functioning. And based on existing infrastructure problems, the renovation plan for the Medan Exemplary Stadium is very feasible.
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When alldigital phase-locked loop(PLL)isapplied in OFDM systems, therearetwoimportant problems thatmustbe solved, namelyhowtonormalize theerrorsignal andhowtoavoid thephenomenon ofout-of-lock inmultipath fading channel. This paperhasstudied thetwoproblems andputforward a suitable solution scheme.Thestudying results showthattheproposed schemecanreally effectively solve theproblem oftiming tracking forOFDM systems andmakePLL worknormally inmultipath fading channels. I. INTRODUCTION Timing tracking isveryimportant inthesynchronization of OFDM systems. Whyshould timing tracking becarried out?The onereason isthat theresidual timing offset isstill existed after timing acquisition, andtheother reason isthatthedifference between sample clock's frequency ofthereceiver andthat ofthe transmitter willresult intiming shifting. Theserious timing offset notonlyresults ininter-symbol interference (ISI) and inter-subcarrier interference (ICI), butalso makesthephases of thedemodulated subcarrier signals generate rotating. Sothe timing offset will haveveryserious effect ontheperformance of OFDM systems.


Almost 50% of new teachers leave the classroom within the first 5 years.1 In the summer of 2011, McDaniel College began a study of its teacher preparation program completers and their employment five years after program completion. Data were collected under the direction of the Coordinator of Teacher Placement and Professional Development and involved contacting completers by phone, email, or in person, and, in some cases, searching the internet for information on school web pages, resulting in the following.


The paper presents an analysis of dynamic properties of a freely moving object equipped with a braking parachute and an accelerating rocket engine. The object is treated as a rigid body with five degrees of freedom. The movement of the object is described by a system of second-order non-linear differential equations. The equations were integrated numerically for the assumed initial conditions. Flight paths, variations of angles of elevation asimuth attack and sideslip, variations of velocity of the centre of mass and its components were calculated for different airdrop parameters. Aerodynamic characteristics were obtained empirically from model testing in a wind tunnel.


We introduce a topological, phase-multiplicative transform for low-light imaging and low-cost image reconstruction. The hybrid, single-shot system solves the phase problem and provides a favorable trade-off, effectively boosting signal-to-noise by lowering resolution and sensitivity.


FlashPack is a fast and simple protocol for capillary column packing. It is developed for the classical 100 bars pressure bomb setup and ultrahigh sorbent concentrations. It provides a 100-fold increase in packing rate and reduces packing time with sub-2 μm sorbents to a few minutes for HPLC columns and to less than an hour for 50 cm UHPLC columns. Custom-produced columns offer performance on par with commercially available capillary columns. Graphical Abstract Highlights Fast and simple capillary column packing protocol. Low-pressure packing at <100 bars from ultrahigh sorbent suspension concentration. Sorbent particle aggregation leading to blocking of the column entrance is avoided. Effective for long capillary UHPLC column packing with a wide range of sorbents. Capillary ultrahigh-pressure liquid chromatography (cUHPLC) is essential for in-depth characterization of complex biomolecule mixtures by LC-MS. We developed a simple and fast method called FlashPack for custom packing of capillary columns of 50–100 cm length with sub- 2 μm sorbent particles. FlashPack uses high sorbent concentrations of 500–1,000 mg/ml for packing at relatively low pressure of 100 bar. Column blocking by sorbent aggregation is avoided during the packing by gentle mechanical tapping of the capillary proximal end by a slowly rotating magnet bar. Utilizing a standard 100-bar pressure bomb, Flashpack allows for production of 15–25 cm cUHPLC columns within a few minutes and of 50 cm cUHPLC columns in less than an hour. Columns exhibit excellent reproducibility of back-pressure, retention time, and resolution (CV 8.7%). FlashPack cUHPLC columns are inexpensive, robust and deliver performance comparable to commercially available cUHPLC columns. The FlashPack method is versatile and enables production of cUHPLC columns using a variety of sorbent materials.


Because of the high specific surface area, good chemical stability, and outstanding electrical and thermal conductivity, graphene is predicted to be an excellent electrode material candidate for energyconversion/storage systems [1]. The nanoscale dimensions of graphene-based materials enable them to be solubilized and transferred into inks, which can be exploited for direct printing of electrodes using additive technology, such as inkjet printing [2]. Inks formulation for application to printable electrodes requires large quantities of material, which can be synthesized by wet chemical routes, such as exfoliation of graphene oxide (GO) from bulk graphite [3]. GO may be subsequently reduced to reduced graphene oxide (RGO) using several methods [4-6]. UV irradiation is a promising method for reducing GO, which allows the simultaneous photopolymerization of acrylic resin matrices, such as poly(ethylene glycol) diacrylate (PEGDA), which can be used in the formulation of inks [7].


Carbon dioxide, oxygen Matawa these field mixing things nad Roh physiological target gas Niyori foamed to other cured wood solution wo including, in particular varicose veins wo treatment to reservoir Roh treatment use form. This form leaves 0.8% Miman Roh nitrogen-containing amount out there. Gas and passed through a curing agent to form a foam, using a canister system pressurized incorporating a fine mesh of micron dimensions can be generated. Alternatively, this form by passing the gas and curable liquid into a fine mesh between the two syringes can be generated. Canister Matawa syringe wo foundation capital to produce goods Nakano nitrogen amount wo minimum mosquitoes is to method Nitsuite explain. Furthermore, using an apparatus based upon the syringe, also discloses a method for simultaneously forming a foam delivery.


The article demonstrates the application of the methodology of cognitive modeling of the socio-ecological and economic system of the city for the development of a sustainable development strategy on the example of Norilsk, conclusions about the priority directions of the city development are obtained.
The active process of urbanization leads to the aggravation of social, economic and environmental problems of the territory. The urban areas of the Arctic region are particularly vulnerable. Most of the cities in this area are single-industry towns of an industrial nature, the
city-forming enterprises of which are primarily engaged in mining, which leads to active pollution of the natural environment. The development of a strategy for the sustainable development of the city, based on a systematic approach that takes into account the diversity and mutual influence of social, economic and environmental aspects, should contribute to the effective solution of existing problems and the stable development of the city. One of the effective ways to implement a systematic approach is cognitive modeling, which allows you to predict development, identify problematic aspects and choose optimal solutions for managing the socio-ecological and economic system that the city represents.
In the course of the study, the authors selected 27 indicators of sustainable development for the city of Norilsk, and based on open information about indicators and dynamics of their development, a weighted oriented graph was developed for the socio-ecological and economic system of the city, on the basis of which the weights of development indicators were calculated and analyzed. As a result, the indicators that need to be developed in the first place were identified and concrete actions for managing the development of the territory were proposed.


Commercially available types of infrared thermal imaging instruments, both viewers (qualitative) and imagers (quantitative) are discussed. The various scanning methods by which thermal images (thermograms) are generated will be reviewed. The performance parameters (figures of merit) that define the quality of performance of infrared radiation thermometers will be introduced. A discussion of how these parameters are extended and adapted to define the performance of thermal imaging instruments will be provided. Finally, the significance of each of the key performance parameters of thermal imaging instruments will be reviewed and procedures currently used for testing to verify performance will be outlined.


Abstract : Quantitative Structure Activity Relationships (QSAR) have been used successfully in the past to develop predictive equations for several biological and physical properties. A subset of QSAR, Linear Solvation Energy Relationships (LSER) have been used by Kamlet and Taft to predict and correlate a wide variety of solute/solvent interactions for over 100 properties. A major difficulty with LSER is the use of empirically derived descriptors. Work done in this laboratory has shown that it is possible to use theoretically determined descriptors such a molecular volume and a molecular polarizability in place of empirical descriptors. This paper describes the search for electronic descriptors to replace or to describe empirical terms related to hydrogen bonding. Keywords include: Quantitative structure activity relationships; Linear solvation energy relationships; and Hydrogen bonding.


A speed estimation method, based on the introduction of a constant frequency carrier signal, is presented. This frequency carrier signal produces a constant speed rotating field from which the speed information in a wide range is obtained. The speed is estimated through the detection of irregularities in the rotor. These irregularities generate frequency pulsations proportional to the rotor speed, which are independent of the parameters of the machine. Because these signals are extremely low, special electronic circuits, implemented with analog multipliers and filters, have been designed, and they are able to measure very low speed values. Computer simulations and some experiments have been carried out, and they have shown that it is possible to measure speeds as low as 20 RPM.<<ETX>>


Invited Talks.- Query Processing in Peer-to-Peer Systems: An Epistemic Logic Approach.- Description Logics in Ontology Applications.- Automated Reasoning in the Context of the Semantic Web.- Formal Versus Rigorous Mathematics: How to Get Your Papers Published.- Research Papers.- Consistency of Variable Splitting in Free Variable Systems of First-Order Logic.- On the Dynamic Increase of Multiplicities in Matrix Proof Methods for Classical Higher-Order Logic.- A Tableau-Based Decision Procedure for Right Propositional Neighborhood Logic.- Cyclic Proofs for First-Order Logic with Inductive Definitions.- A Tableau-Based Decision Procedure for a Fragment of Graph Theory Involving Reachability and Acyclicity.- Embedding Static Analysis into Tableaux and Sequent Based Frameworks.- A Calculus for Type Predicates and Type Coercion.- A Tableau Calculus with Automaton-Labelled Formulae for Regular Grammar Logics.- Comparing Instance Generation Methods for Automated Reasoning.- An Order-Sorted Quantified Modal Logic for Meta-ontology.- A Redundancy Analysis of Sequent Proofs.- A Tableau Algorithm for Description Logics with Concrete Domains and GCIs.- The Space Efficiency of OSHL.- Efficient Query Processing with Compiled Knowledge Bases.- Clausal Connection-Based Theorem Proving in Intuitionistic First-Order Logic.- Automatic 'Descente Infinie' Induction Reasoning.- A Decision Procedure for the Alternation-Free Two-Way Modal ?-Calculus.- On the Partial Respects in Which a Real Valued Arithmetic System Can Verify Its Tableaux Consistency.- System Descriptions.- Pdk: The System and Its Language.- Proof Output and Transformation for Disconnection Tableaux.- LoTREC: Logical Tableaux Research Engineering Companion.- A Tableau-Based Explainer for DL Subsumption.- CondLean 3.0: Improving CondLean for Stronger Conditional Logics.- The ILTP Library: Benchmarking Automated Theorem Provers for Intuitionistic Logic.- Unit Propagation in a Tableau Framework.


Reported here are the systems and activities of "die Vogelwarten" in West Germany, visited by the author in May-June 1977. These ornithological institutes are in Helgoland, Wilhelmshaven, and Radolfzell.Bird-ringing began in Germany from 1903, using the rings of Vogelwarte Rossitten. Now, two kinds of rings are used in West Germany. One is for the northen regions and the other is for the southern. Annually, more than 370.000 (individuals of) birds are ringed by about 770 amateur ringers.At the Vogelwarte Helgoland, using the well-known Helgoland-traps and several other traps (for Doves, Crows and Sparrows), elaborate research is being carried out throughout the year.The Institute for Ornithology of Wilhelmshaven acts as one of the two bird-ringing centers in West Germany. At this institute are studied behavior of gulls and discriminating ability of Oystercatcher in laboratory.Also I visited to Vogelwarte Radolfzell, the other birdringing center. Near the Vogelwarte, thare is the Mettnau bird ringing station, which belongs to a long-term bird ringing and research program (Mettnau-Reit-Illmitz program). The aim of this program is to study not only migration but also many other items; population dynamics, biorhythmic, research for ecosystems and methodology.I would like to thank heartily Dr. G. Vauk, Dr. D. Moritz and Mr. E. Sohonart of Helgoland, Dr. W. Winkel and Mr. H. Rogall of Wilhelmshaven, Dr. G. Zink, Dr. P. Becker, Dr. J. Holzinger and Mr. F. Bairlein of Radolfzell, and also all the others at the three Vogelwarten, for their very kind hospitality given to us during our stay.


Unidirectional composite laminates based on carbon fibers (CF) and high-performance polyethylene fibers (PEF) and their hybrids were prepared with partially polymerized methyl methacrylate (MMA) at room temperature, followed by heating at 55°C (well below the softening point of PEF, 147°C) for 2 h. The stress-relaxation behavior of the composites were determined and analyzed. It was found that at all strain levels the rate of stress relaxation decreased by the loading of CF in CF-reinforced composite laminates (CFRC); however, the reverse behavior was found in the case of PEF-reinforced composite laminate (PEFRC). An interesting observation of the study was that the rate of stress relaxation decreased linearly in two steps in the case of PEFRC, whereas in the case of CFRC, it decreased in a single step. In the case of hybrid composites, the stress relaxation decreases in two steps as in PEFRC.


The wireless network evolution, delineated during the last years, has urged the necessity to extend the up-to-now static business environment to a mobile and wireless one. However, the current and forthcoming wireless technologies are characterized by different attributes regarding the coverage area, offered bandwidth and delay. The transparent conjunction of various wireless technologies into a single mobile terminal can further boost the wireless explosion. This paper presents the architectural approach and the results concerning the continuous connectivity and seamless switching between two complementary wireless networks, one 802.11-compliant in the short area and a CSM in the wide area. The described experiments were performed on an open, IP-based wireless architecture that can be easily extended to accommodate future wireless networks.


s are available on ACCA web site http://www.escardio.org/ communities/ACCA/education-research/Pages/2014-researchprize.aspx. Following the success of the inauguration of the ACCA Research Prize in Acute Cardiovascular Care, the enthusiasm created and the excellent research presented by the finalists, the ACCA is proud to announce the continuation of this highly prestigious research prize in Acute Cardiovascular Care during the coming years. Don't miss the next edition in Vienna!!! Submission for the 2015 ACCA Research Prize in Acute Cardiovascular Care will open on 1 June 2015 and close on 30 June 2015. Acute Cardiovascular Association European Heart Journal Podcasts The new series of European Heart Journal Podcasts have begun and are discussed by Anna Whiting Since 1980, the European Heart Journal (EHJ) has been at the cutting edge of providing material on all aspects of cardiology of the highest quality. Our readers' needs change, and the means of obtaining access to content have broadened significantly in the past 34 years. With the rise of the internet, audio, and mobile devices, how people read the latest in cardiology varies widely. Not only can readers access via a print subscription, they can read online, read from their mobile devices, and download full issues via the ESC Journals app for off-line browsing. Now for the first time, readers can also subscribe to the new EHJ Podcasts, which launched in August 2014 with audio abstracts of the 10 Hotline papers published to coincide with the ESC Congress 2014. The podcast series continues with an audio commentary linked to Renal denervation: Symply trapped by complexity? by Dr Felix Mahmoud and EHJ Editor-in-Chief Professor Thomas Lüscher. This editorial links to Predictors of blood pressure response in the SYMPLICITY HTN-3 trial, an important piece of clinical research documenting the recent results of the SYMPLICITY HTN-3 trial which have challenged preclinical science, clinical anecdotes, and the consistency observed across early phase trials. The EHJ podcast series joins the established suite of digital offerings from the EHJ, building pathways for readers to discover and access the high-quality articles published in the EHJ. Each future podcast will publish in conjunction with a key paper providing an audio summary of the article which you can download and listen to for free. To listen to the podcasts, readers should simply go to the EHJ homepage and click the link to EHJ Podcasts; from there you can listen in your browser, or subscribe to listen via podcast managers such as iTunes, and receive the latest podcasts straight to your device. With the addition of the EHJ podcast series all readers can now listen, watch, and read cutting edge research from the EHJ anytime, anywhere. Bettina Heidecker, MD The personal experiences of an émigré cardiologist from Austria to the USA Austrian cardiologist Bettina Heidecker first went to the USA as a medical student in 2004. Today she practices cardiology and conducts clinical research at the University of California, San Francisco (UCSF). Heidecker is International Lecturer in Cardiology at the Aston Medical School in Birmingham, UK. She is also Director of the Scientific Advisory Board of Heart Genomics. Heidecker's interest in medicine started during her school years as a Red Cross volunteer. She followed her passion for medicine and joined the Medizinische Universitaet in Innsbruck, Austria. Having completed all graduation requirements at the age of 22, she decided to pursue a thesis on the role of T-lymphocytes in the development of atherosclerosis. Her mentor, Georg Wick, MD, inspired her to apply to the Johns Hopkins University in Baltimore. With his support she was fortunate enough to get accepted as a visiting medical student. Heidecker describes her work with Gary Pasternack, MD PhD in cancer research at Johns Hopkins, as one of her major career highlights. By the end of her term he encouraged her to return for a full-time position as a research scientist. In 2006 Heidecker returned to Johns Hopkins as a post-doctorate fellow in the cardiovascular laboratory of Joshua Hare, MD—a CardioPulse 401 Downloaded from https://academic.oup.com/eurheartj/article-abstract/36/7/398/494469 by guest on 29 July 2018 renowned clinician-scientist in heart failure and cardiomyopathies. Heidecker's experience at Hare's lab has shaped her research career. It was in his lab where she discovered her deep interest in cardiology. Hare providedherwith autonomy,professional guidance, and inspiration to pursue clinically relevant research in the field of transcriptomic biomarkers in myocarditis and heart failure. Bettina Heidecker and Joshua Hare 'Myocarditis is a disease affecting many young individuals. Currently we lack sufficient understanding of its pathophysiology to improve specific treatment. With current standard diagnostic techniques a large number of patients with myocarditis remain under-diagnosed and therefore do not receive appropriate treatment. At Hare's lab we discovered a transcriptomic biomarker that detects myocarditis with very high accuracy at disease onset'. 'For our project on transcriptomic biomarkers we had access to 350 biopsies collected over the course of 10 years from patients at the onset of heart failure. My first task was to develop a technique to isolate sufficient RNA to perform microarray analysis without any additional amplification. Once the technique was optimized to a 99% success rate in practice samples obtained from animal tissues, I processed all human samples at once to avoid batch-bias. It almost felt as if time had stopped when I opened the raw data from the microarray core. If something had gone wrong in the processing of samples, we would have lost 10 years of valuable biopsies. Fortunately, the data passed all quality control tests, and the results were plausible and reproducible in an independent validation set of samples. We discovered a distinct diagnostic biomarker for myocarditis that takes us one stepcloser to saving livesby earlier detection of the disease'. Heidecker's analysis also uncovered an additional biomarker that very accurately predicts the 5-year survival of patients with new onset heart failure. Heidecker's work was recognized by the American Heart Association, the Heart Failure Society of America, and the Myocarditis Foundation, winning her multiple prestigious awards including the Samuel A. Levine Award and the Jay N. Cohn New Investigator Award. Her findings were featured in the seminal cardiology textbook Braunwald's Heart Disease. The Myocarditis Foundation was especially helpful for Heidecker through its financial support and the mentorship of Leslie Cooper, MD, and DeLisa Fairweather, PhD. After completing residency training in internal medicine at the University of Miami, Heidecker's growing interest in cardiovascular medicine led her to pursue clinical training in cardiology. She is currently in her third year of the cardiology fellowship programme at UCSF, one of the most demanding and rigorous training programmes in the USA. 'As I would like to combine research, clinical work, and teaching as part of my career I could not have hoped for a better training ground than the UCSF programme under the leadership of Michael Crawford, MD and Jeff Olgin, MD. UCSF is one of the biggest heart transplant centres in the US, and our faculty comprises many internationally acclaimed experts in a wide array of cardiac disorders. Working side by side with experts such as Theresa DeMarco, MD in the field of heart failure and Joel Karliner, MD in the outpatient clinic, creates an unparalleled clinical environment for my professional growth. During my third year I am focusing my time on advanced echocardiography training, and I could not think of better mentors than Nelson Schiller, MD, who was instrumental in developing the field, and Elyse Foster, MD, who is my role model as a successful woman in cardiology'. Heidecker continues to follow her passion for cardiovascular research. She is currently working under the mentorship of Peter Ganz, MD—a pioneer in atherosclerosis and vascular biology. Her research relies on technology Ganz has contributed to over the past decade that uses aptamers, small nucleotides, to quantify a protein of interest with high sensitivity and specificity. Heidecker is using this technology to evaluate the role of growth differentiation factor-11 (GDF-11) in left ventricular hypertrophy and its correlation with cardiovascular outcomes such as stroke, myocardial infarction, and heart failure. For her research Heidecker obtained access to the Heart and Soul Database—abiobank containing clinical data andplasma samples that have been collected over a course of 10 years. The biobank was established as part of a clinical study directed by Mary Whooley, MD—UCSF faculty member and Heidecker's co-mentor. 'The access to outstanding mentors and resources at UCSF such as the Heart and Soul Database enables me to efficiently conduct translational research that has potential for clinical applications'. Heidecker recommends finding a niche in a supportive environment. 'It is important to pursue your passion with the perseverance it deserves. But this is only half the picture. You also need to choose an environment that shares your enthusiasm, rewards your determination, and trusts your competency in order to grow and succeed'. CardioPulse 402 Downloaded from https://academic.oup.com/eurheartj/article-abstract/36/7/398/494469 by guest on 29 July 2018 People's corner: Mouaz Al-Mallah MD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Dr Mouaz Al-Mallah establishes


Future high energy physics experiments at the energy and intensity frontiers will face challenges of a severe radiation environment from both ionization dose and charged and neutral hadrons. In this paper, we report an investigation on charged hadron-induced radiation damage in BGO, LYSO/LFS, PWO and a LYSO/W/Capillary shashlik cell by using 800 MeV and 24 GeV protons at LANL and CERN respectively. Degradations in both transmittance and light output are reported. The results show excellent radiation resistance of LYSO/LFS crystals and the LFS/W/Capillary shashlik cell against charged hadrons.


[For the English abstract and full text of the article please see the attached PDF-File (English version follows Russian version)].ABSTRACT Growth in demand for rapid passenger transportation, shown in the article, allows to fix the value of such an indicator of quality of service as travel time. Ways to improve the quality of transport services of passengers by railway companies were revealed and substantiated on the basis of the model of factor groups. Transport market coverage extension was recommended for the purpose of marketing, and deepened demand analysis. Age-related differences in the preferences based behavior of passengers when choosing transport mode were underlined. Keywords: transport, railway, civil aviation, market, competition, quality of service, passenger transportation, marketing research, demand factors.


Hongtoushan Copper Mine is the deepest underground metal mine in China. With the mining depth increasing, mining in high stress condition is the major factor leading to rockburst hazards, and that has been a dominant problem in this mine. Rockbursts induced by high-stress mining often cause production losses, damage to equipment, collapse of roadways and stopes, even loss of life. In this paper, in order to analyse the mechanics and dynamics of rockburst during mining process, a FLAC2D (3.0) numerical model was set up and analysed the stress field distribution of cut and fill method during the total stoping process. Numerical modelling results show that the high stress concentration area appears when the stoping height is 32–48 m. The main failure modes are spalling and bursting in the sidewall, which is accordance with field investigations. In order to analyse the mechanics of bursting induced by blasting energy, different blasting energies were considered and analysed by using FLAC2D dynamic analysing method. Numerical results show a blasting energy can induce the rockburst when the pillar/sidewall is in a high stress condition. Meanwhile, destress blasting was applied to control the high stress distribution and reduce the rockburst hazards, which is valuable for providing the knowledge used to improve the stability of mine excavations.


In an attempt to capture a greater share of the symbolic value of coffee in the market, some producers have started to safeguard the geographical names of specific origins through Geographical Indications in their home country, and then subsequently registering Protected Geographical Indications (PGI) under European Union (EU) law. To enable effective value capture, such initiatives require successful collective action. We explain how the need for collective action has manifested within four coffee Protected Geographical Indications in Colombia, Indonesia and Thailand (2 cases). Based on the Institutional Analysis and Development (IAD) framework developed by Elinor Ostrom, we examine the cases following a common analytical approach, encompassing: i) contextual setting of product and territory; ii) actors involved; iii) institutional arrangements and action arena; and iv) the outcome of these arrangements. The cases involved a diversity of applicants including a producer association (Colombia), a social foundation and a private company (Thailand), and a government-supported consortium (Indonesia). The process of institutionalizing the GI required powerful, and well-resourced actors to assume a lead role resulting in relatively little participation from actual producers themselves. Therefore, this does not truly satisfy the IAD requirements for effective collective action, such compliance with the EU requirement for collective action was mainly observed as an administrative formality. The design of guiding rules for collective action processes are seen to significantly affect their effectiveness and the distribution of any benefits generated. This article emphasizes how this design is shaped by the positionality and particular interests of the actors involved, their different capacity to exert power and influence, their diverse attitudes towards moral legitimacy, and varying relationships with external actors such as development agents, research organizations and state agencies.


Through SEM observation from natural and experimental examples of rocky materials, nanocoating texture was found on the shear slip surface (plane, lamellae). Our researching suggested that the nanocoating possesses some textural characteristics including granular, delaminating and rheological one. In general, single nano-sized grain (40-80 nm in diameter) with moderate roundness and sphericity could aggregate into the compound grain, and thickness of the nanocoating (thin shell, film) might reach from μm to cm scale in different rocky materials. Development of the nanocoating textures of shear slip surface could be subdivided into three stages, i.e. strain hardness, strain softening and strain decaying stage, and its forming mechanism is quite similar to the "tribological white layer" which is very common phenomena in metallography. Furthermore, it is determined that the nanocoating lamellae in rocky materials might be capable to constitute a shelter for a reservoir.


In the research fields of earnings forecast and the behavior of cost accounts there are many studies that indicate factors that affect earnings and factors that are affected by the cost accounts. Earnings affected by many factors as investments, cash flows, ROI, cost of capital, size, and others. Also in the area of earnings management crucial factors that affect earnings are inventories, accounts receivable, accounts payable, depreciation expense, accrued liabilities and others. Resent research in cost accounting field addresses the stickiness of CGA cost as an important factor that may be affect earnings or stock return in all industries except financial service industry. The stickiness of cost has investigated mostly in SGA cost because the manufacturing cost, inventory and cost of goods sold, change proportionately with activity levels that it means that are mostly variable factors. This empirical study investigates the impact of manufactory cost and SGA to operating income in manufacturing industry, using data from 2.128 listed firms, separated in three sectors according to sales level. The findings show that manufacturing cost and SGA cost affects the operating income differently in the three levels. This result disclosures the need for further investigation in separated industries, in different countries and finally to find a stable forecasting model using the cost accounts.


This article is to investigate the reasons for the existence of land rent in China in the socialist market economy system based on the Marx's absolute land rent theory and the differential land rent theory. The problems of the farmland system,which include the vague definition of the land property right,farmers' low investment enthusiasm,the inconvenience of the farmland transfer and the unreasonable allocation of land rent,are revealed in the essay. Moreover,the essay provides some advices to improve the farmland property right system,contracting system,transfer system and land requisition system.


Objective To study the effects of low dose exposure to methylenediphenyl diisocyanate(MDI)and toluene diisocyanate(TDI)on bodys immune function.Methods The workers were divided into Group Ⅰ and Ⅱ exposed to MDI,Group Ⅲ exposed to TDI and control Group unexposed to MDI or TDI.Their serum concentrations of IgG,IgA,IgM,IgE and interleukin 2 receptor(IL 2R)were determined.Serum levels of IgG and IgE against MDI and urine level of MDA in the Groups Ⅰ and Ⅱ exposed to MDI and in controls were determined.Results Serum leverls of IgG and IgA in the Group Ⅰ exposed to MDI were significantly lower than those in controls(P0 01).Serum levels of IgG,IgA and IgM in the Group Ⅲ exposed to TDI than those in controls,and serum level of IL 2R in the Group Ⅲ increased significantly(P0 01).Positivity of serum IgG and IgE against MDI increased with length of employment and urine level of MDA correlated well with serum level of IgG against MDI.Conclusion No obvious allergic symptoms were caused in the exposed workers by long term exposure to low dose MDI and TDI,but their immune function was affected to varied extent.Serum IgG against MDI is a sensitive biomarker indicating exposure.


Reactions between dicarboxylic acids and diols in the melt and leading to an equilibrium yield quantitative results which may be applied to the kinetics of some partial reactions of polyesterification. The relationship of the rate constants of the forward and the reverse reaction as well as of the equilibrium constant furnish valid results both in the absence of catalyst and in the presence of acid or basic catalysts. The values obtained for the energy of activation of the forward and the reverse reaction and of the overall reaction (13 ± 1 kcal/mole) also are in good agreement.


Emodin, a widespread natural anthraquinone, has many biological activities including health-protective and adverse effects Amongst beneficial effects, potential antiviral activity against coronavirus responsible for the severe acute respiratory syndrome outbreak in 2002–2003 has been described associated with the inhibition of the host cells target receptors recognition by the viral Spike protein However, the inhibition mechanisms have not been fully characterized, hindering the rational use of emodin as a model compound to develop more effective analogues This work investigates emodin interaction with the Spike protein to provide a mechanistic explanation of such inhibition A 3D molecular modeling approach consisting of docking simulations, pharmacophoric analysis and molecular dynamics was used The plausible mechanism is described as an interaction of emodin at the protein–protein interface which destabilizes the viral protein-target receptor complex This analysis has been extended to the Spike protein of the coronavirus responsible for the current pandemic hypothesizing emodin's functional conservation This solid knowledge-based foothold provides a possible mechanistic rationale of the antiviral activity of emodin as a future basis for the potential development of efficient antiviral cognate compounds Data gaps and future work on emodin-related adverse effects in parallel to its antiviral pharmacology are explored


To estimate and compare the incidence of dentin hypersensitivity among men and women in an adult population sample who required replacement of missing tooth/teeth with a fixed partial prosthesis. Study population consisted of 28 subjects, 14 men and 14 women, who visited the OPD for replacement of missing tooth/teeth with a fixed partial prosthesis (FPD). After a clinical examination, the patients were asked to grade their overall sensitivity using a 10 cm Visual Analogue Scale (VAS)4,5 labelled at the extremes with "no pain," at the zero cm end of the scale, and "severe pain," at the 10 cm end of the scale following tactile and thermal stimulation and following tooth preparation. Data was analyzed using descriptive statistics, Mann-Whitney U test and Wilcoxan signed rank test. Women reported more sensitivity than men before (p=0.880) and after tooth preparation (p=0.520). Women were more sensitive than men (p=0.001) on tactile and thermal stimulation before tooth preparation. The results showed that women reported more dentin hypersensitivity than men before and after tooth preparation.


This study was con ducted in or der to eval u ate the abil ity of car bon ions to in duce DNA dou -ble-strand breaks and apoptosis in the ra dio-re sis tant hu man HTB140 mel a noma cells. The cells were ir ra di ated with 12 C ions hav ing the lin ear en ergy trans fer of 258 keV/ (cid:109) m. Ir ra di a tions were per formed in the dose range from 2 to 16 Gy. In duc tion of DNA dou ble-strand breaks was eval u ated 2 hour af ter ir ra di a tion through ex pres sion of g H2AX pro tein. In creased level of g H2AX de tected in ir ra di ated sam ples was es pe cially high af ter ir ra di a tion with 12 and 16 Gy. Dose de pend ent in crease of apoptosis was de tected 48 hour af ter ir ra di a tion by flow-cytometry, with the max i mum value of 20.4% af ter ir ra di a tion with 16 Gy, and the apoptotic in dex of 9.3. Pro-apoptotic ef fects of car bon ion beams were con firmed by changes of key mol e cules of the mi to chon drial apoptotic path way, p53 pro tein ex pres


In this paper we are analysing logistical surveys. The surveys assess the level of best practices application within manufacturing companies and are processed in our prototype of a machine-learning system combining categorical data and numerical financial data building value factors. We extended the meta-data phase measuring dissimilarities between different modal variables. The main objective is to find patterns in the distribution of the results that can be translated in general rules.


Abstract The feeder service plan (FSP) of cargo express train aims to utilize the train resources in railway hub in a more cost-effective way. So far in China, the feeder service operating mode with hump yard (FSOMH) in railway hub cannot meet freight transport demand, because of their low level of service. To improve the level of service of cargo express trains, a new feeder service operating mode with hump yard and railway logistics centre (FSOMHR) is proposed in this paper. A mixed integer programming model is also presented, which is based on a service network in railway hub. This model aims to minimize the cost of the cargo express train organization and number of local trains. In addition, the service time constraint and capacity constraint of service arcs are considered. The case study based on Hangzhou railway hub shows that the proposed solution method yields a better FSP. Under the FSOMHR, the departure volume of railcars increases by 58.70%, compared to FSOMH.


The CIBSE Building Energy Code Part 2(a) was devised as a method of assessing the energy performance of designs for heated and naturally ventilated buildings. This paper presents the authors' experience in teaching the use of the Code, primarily to building services undergraduates, and the value of developing this into an educational tool to raise students' awareness of energy issues in buildings. There are a number of other significant educational benefits. Projects along these lines could be adapted to suit other professions in the building industry. Some example results are presented, together with some broad conclusions drawn by both students and the authors on the validity of the Code as a general tool. Its strengths and weaknesses are discussed and further work suggested.


The present invention is a trivalent power is 7 ~ 60W in an aqueous solution containing arsenic and iron comprising: frequency generating the OH radical by applying ultrasonic waves of 280 ~ 600㎑; The third step of the oxidation of arsenic to the OH radical. 5 is formed of arsenic; Relates to the removal of arsenic method comprising the step of forming an iron complex-and the 5 to Arsenic and iron-arsenic reaction.


This report describes a newly developed sealing method for tunnels and shafts showing many advantages, such as the possibility of sealing on a wet and and rough surface and the tight fixation of the placed sealing cover. By using compressed air, this sealing method allows an objective test of the butt joints with regard to water-tightness and mechanical density. It has been used with great success on various Swiss and Austrian tunnel and shaft projects, including: (1) Ventilation-Shaft Lerche near Dortmund (Germany); (2) vertical ventilation-shaft of the Gotthard highway tunnel (longest tunnel in the world); (3) vertical ventilation-shaft Tauern-Tunnel, greatest shaft of the world, for the Saizburg-Villach highway; (4) vertical ventilation shaft Hattig for the Seelisberg tunnel, connection of the Swiss National Highway Basel-Chiasso; (5) underground railway Vienna; and (6) city railway Frankfurt a.M.


more than coincidence and suggests that the personal taste of the king was the governing factor. An even more striking example than either of these two churches is that of Roslin. Founded as a collegiate chapel by William Sinclair, Earl of Caithness and Orkney, and built by 1446 it is like no other building in Scotland. With an exuberance of detail that is Iberian in origin, and an intended nave based on that of the recently completed cathedral of Gerona, it can only be explained as a whim of the founder. There are points where Mr Cruden's views must be queried. The introduction of an upper floor into the western transepts at Kelso, for which 'the absence of evidence is not evidence of absence' is a particularly devious piece of pleading, however perfectly phrased, although it is more than compensated for by the more general and original discussion of the planning of the west ends of the two other Tironesian houses of Arbroath and Kilwinning. His positioning of the ritual choir at Glasgow west of the crossing must also be doubted. Given the internal levels of the cathedral and the fact that it was a secular foundation, this is unlikely. These, however, are minor points in a book which must be regarded as the most important contribution to studies in this field that has appeared this century and which is written in language that is a joy to read. And that is something which is very rare these days. H. GORDON SLADE


The seed-metering device is the key component of a precision seeder. The methods to improve the seed suction and dropping efficiency of air suction drum precision seed metering device were discussed Establishing the force and equation of motion for sucking, carrying and dropping stages, the effect of the seeding parameters on the effect of sucking and seeding is analyzed. Then, the single factor and orthogonal test are carried out on the sucking pressure, the carrying pressure, the rotation rate and the dropping pressure as the experimental factors for the optimization analysis. And the optimum experimental parameters and the predicted values of each test index are obtained. That is, when the seeding pressure of -2.87kPa, the seeding pressure of -1.91kPa, the drum rotation rate of 18.72 r min-1 and the dropping pressure of 1.74kPa, the best effect that the single rate is 93.8%.


TPS10072 Background: Outcomes remain poor for patients (pts) with relapsed or refractory (r/r) B-cell malignancies such as acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL). CD19 is an attractive therapeutic target because it is widely expressed on normal and malignant B cells throughout B-cell maturation but not on pluripotent stem cells or non–B-cell tissues. We have developed chimeric antigen receptor T cells to target CD19+ cells (CART-19 or CTL019). This approach involves patient-derived T cells that are genetically modified via lentiviral transduction to express a CD19 antigen recognition domain attached to intracellular signaling domains (TCRζ and 4-1BB) that mediate T-cell activation. A recent study in CLL showed that CART-19 therapy had potent activity with responses in 5/8 evaluable pts (3 CR, 2 PR). Pts achieving CR (two > 24 months and one > 5 months) remain in CR with detectable CART-19 cells (Porter et al. ASH 2012). Here we describe a study of CART-19 therapy in pedi...


In the article decision management in a global currency market "FOREX"" model is presented. The model is based on the adequate for investment profit stochasticity assessment portfolio earlier suggested by the author, including portfolio and currency exchange rates fluctuations forecasting system, used to evaluate decisions reliability. The possibilities of model practical application are presented. Experimental results of the model application enable us to state that global currency and capital markets are not homogeneous, that almost always there are possibilities to find a decision management strategy, permitting to have advantage over overall market decisions made, using only historical market data.


This study examined the appraisal of wind resources of Ilorin, Nigeria for vortex-induced wind turbine power generation and off-grid electrification. The technical potential of Modern-Era Retrospective Analysis for Research and Application, version 2 (MERRA-2) was employed as a tool to generate an estimated wind resource of Ilorin city, using five different hub-heights (10, 30, 50, 70, and 90 m). A statistical analysis of wind characteristics for 21 years from 2001 to 2021 was carried out using Weibull distribution function. The daytime and night-time wind characteristics were studied to determine prospective and investment hub-height(s). It was observed that the study area is a low wind region with a minimum and maximum mean wind speed of 2.89 m/s at 10 m and 7.68 m/s at 90 m, respectively. Wind turbines with cut-in wind speed of 2, 2.5, and 3 m have operational chances of 98%, 95% and 88%, respectively. Wind power density at 10, 30, and 50 m elevations was classified as poor while at 70 and 90 m elevations, was regarded as marginal and fair, respectively.


Abstract The ability of dysphasic subjects to name pictures has been shown to benefit from carrying out simple semantic discrimination tasks. Previous experiments have failed to find generalization of this improvement to related items even when these are used as distractors in the tasks. To improve the possibility of such generalization an experiment was carried out in which sets of items were drawn from a single functionally related category. Improvement was found for items directly targeted in the therapy task and for items which appeared as distractors. The former improved significantly more than the latter. Related items which did not appear in the therapy did not improve. Thus generalization is limited to items which appear during the therapy task.


Workplace bullying in Colombia is one of the issues of greatest concern to psychologists involved in human talent because people who suffer refer felt bullying in most cases, and this will have to repeat in other companies you enter the person.
This paper seeks to make a background mobbing in Colombia all based on the state of art theme and found the statistics of the current rates of workplace bullying, the same way the behaviors that are considered harassment arise and how they are impacting the candidate on the different aspects that are around. Context labor and bullying arises in Colombia.
Finally is to determine according to the law and as a psychological approach can prevent bullying in companies.


Based on gelling matrices and ionic liquids (ILs), monolithic ionogel electrolyte membranes (MIEMs) have become a research focus. However, further application is limited by lack of functional matrices. Herein, we proposed the introduction of an ionized polymer, i.e., polyether polymer with side-chain ionic groups obtained via the reaction of quaternary ammonium with uncrystallizable poly (epichlorohydrin) (PECH), as the matrix into the gels to balance the mechanical properties and the ionic conductivity. In combination with lithium bis-(fluorosulfonyl) imide (LiFSI) and 1-ethyl-3-methylimidazolium bis-(fluorosulfonyl)-imide (EMImFSI) via a solvent casting technique, a flexible MIEM was successfully prepared. The as-obtained MIEM exhibited good thermal stability (up to about 250 °C) and a high ionic conductivity of 1.21 mS cm−1 at 20 °C. Moreover, Li|LiFePO4 coin cells using this MIEM delivered high capacity (150.0 mA h g−1 at 0.2C) with good cycling stability, and an excellent C-rate response. This work discloses a novel and paramount route to exploit PECH-based MIEMs for Li storage, as well as energy storage systems beyond Li.


A novel ultrasonic inner-loop bioreactor was used for artemisinin production by adventitious shoots in a multiplate culture of Artemisia annua L. The bioreactor was designed to allow the nutrient mist to uprise along a concentric draught-cylinder until it overflows from the top opening and the side-holes of the central tube downward and out of the annulus, so that the nutrient mist can be fulfilled in the bioreactor within 2 similar to 3 minutes. Under the misting cycles of every 3-minute misting in every 90 minute interval, artemisinin production reached totally 46.9 mg DW/L of culture medium at an airflow rate of 0.5 L/min for 25 d of culture in batches. The product amounted 2.9 and 3.2 folds of those obtained from culturing in solid medium and in shaking flasks respectively.


The Metropolitan Atlanta Rapid Transit Authority (MARTA) is constructing a rapid transit system in Atlanta, Georgia. Finite element studies were conducted to assess the response of the rock mass when openings were made.


In this paper, the trade-off between energy efficiency (EE) and spectral efficiency (SE) is analyzed for both the uplink and downlink of the distributed multiple-input multiple-output (DMIMO) system over the Rayleigh fading channel while considering different types of power consumption models (PCMs). A novel tight closed-form approximation of the DMIMO EE-SE trade-off is presented and a detailed analysis is provided for the scenario with practical antenna configurations. Furthermore, generic and accurate low and high-SE approximations of this trade-off are derived for any number of radio access units (RAUs) in both the uplink and downlink channels. Our expressions have been utilized for assessing both the EE gain of DMIMO over co-located MIMO (CMIMO) and the incremental EE gain of DMIMO in the downlink channel. Our results reveal that DMIMO is more energy efficient than CMIMO for cell edge users in both the idealistic and realistic PCMs; whereas in terms of the incremental EE gain, connecting the user terminal to only one RAU is the most energy efficient approach when a realistic PCM is considered.


Background: Increased metabolic profiles during pregnancy are associated with an increasing risk for maternal and fetal morbidity and remain a significant medical challenge. To our knowledge there are no reports on the favorable effects of calcium supplementation plus aspirin on metabolic profiles among pregnant women at risk for pre-eclampsia. Objectives: This study was designed to determine the favorable effects of taking calcium supplement plus low-dose aspirin on metabolic profiles among Iranian pregnant women at risk for pre-eclampsia. Patients and Methods: This randomized, double-blind, placebo-controlled trial was conducted on 54 primigravida pregnant women, aged from aged 18 to 40 years with gestational age of 27 weeks and positive roll-over test. The population under study was randomly divided into two groups each including 27 subjects. The case group received 500 mg calcium supplement plus 80 mg aspirin for 9 weeks, compared with untreated placebo control group. Fasting blood samples were taken at baseline and after intervention period to measure fasting plasma glucose (FPG) and serum lipid profiles. Results: As compared to the placebo, consumption of calcium supplement plus low-dose aspirin resulted in a significant difference in serum triglycerides levels (8.8 vs. 51.7 mg/dL, P = 0.03). However, no significant differences were found between case and the placebo groups regarding fasting plasma glucose (FPG), and serum total, HDL, LDL cholesterol levels. As for the placebo group, significant increases were observed in serum total cholesterol (+ 12.4 mg/dL, P = 0.01) and triglycerides levels (+ 51.7 mg/dL, P < 0.0001). Conclusions: The consumption of calcium supplement plus low-dose aspirin for 9 weeks in pregnant women at risk for pre-eclampsia resulted in significant reduction in serum triglycerides levels compared to the placebo group, but did not affect FPG and other lipid profiles.