This paper aims to handle the conceptual framework within which critics present home. It helps us think about our relationship with home and examine questions about the problem of displacement directing research to Third World. This overview provides the vocabulary for articulating this dilemma. Regarding methodology, the paper is an in-depth qualitative study based on views of selected critics. The findings have indicated that applying the critics' reflections on the conditions of people is advocated to detect whether homing is attainable or still remains a desire aspired to. Hence, the paper, as a preliminary study, stimulates for further research.


In an environment where software development is expanding in scope, it is necessary to develop new techniques that can be used to identify defects in a product, while at the same time keeping the cost of product certification to a minimum. For the initial deployment of any software, there is no way to get around performing a complete test of the product. However, subsequent iterations of software development require complete testing of the new features, and regression-testing of the existing features using orthogonal defect classification. Random sampling techniques may also be used; but unless they are properly designed, run the risk of not being adequately representative of the whole array of test cases. Using orthogonal arrays, we can break the test cases down into categories, thereby reducing the amount of testing without sacrificing the quality of the deliverables.


In this paper we have designed and implemented(15, k) a BCH Encoder on FPGA using VHDL for reliable data transfers in AWGN channel with multiple error correction control. The digital logic implementation of binary encoding of multiple error correcting BCH code (15, k) of length n=15 over GF (2 4 ) with irreducible primitive polynomial x 4 +x+1 is organized into shift register circuits. Using the cyclic codes, the reminder b(x) can be obtained in a linear (15-k) stage shift register with feedback connections corresponding to the coefficients of the generated polynomial. Three encoder are designed using VHDL to encode the single, double and triple error correcting BCH code (15, k) corresponding to the coefficient of generated polynomial. Information bit is transmitted in unchanged form up to k clock cycles and during this period parity bits are calculated in the LFSR then the parity bits are transmitted from k+1 to 15 clock cycles. Total 15-k numbers of parity bits with k information bits are transmitted in 15 code word. Here we have implemented (15, 5, 3), (15, 7, 2) and (15, 11, 1) BCH code encoder on Xilinx Spartan 3 FPGA using VHDL and the simulation & synthesis are done using Xilinx ISE 13.3. BCH encoders are conventionally implemented by linear feedback shift register architecture. Encoders of long BCH codes may suffer from the effect of large fan out, which may reduce the achievable clock speed. The data rate requirement of optical applications require parallel implementations of the BCH encoders. Also a comparative performance based on synthesis & simulation on FPGA is presented. Keywords: BCH, BCH Encoder, FPGA, VHDL, Error Correction, AWGN, LFSR cyclic redundancy checking, fan out .


Preclinical testing in animal models is a critical component of the drug discovery and development process. While hundreds of interventions have demonstrated preclinical efficacy for ameliorating cognitive impairments in animal models, none have confirmed efficacy in Alzheimer's disease (AD) clinical trials. Critically this lack of translation to the clinic points in part to issues with the animal models, the preclinical assays used, and lack of scientific rigor and reproducibility during execution. In an effort to improve this translation, the Preclinical Testing Core (PTC) of the Model Organism Development and Evaluation for Late‐onset AD (MODEL‐AD) consortium has established a rigorous screening strategy with go/no‐go decision points that permits unbiased assessments of therapeutic agents.


1 Department of Physical erapy, National Cheng Kung University, Tainan 701, Taiwan Department of Physical erapy, China Medical University, Taichung 404, Taiwan Division of Physical erapy, Department of Physical Medicine and Rehabilitation, Cheng Hsin Rehabilitation Medical Center, Taipei 112, Taiwan Department of Food Sciences and Technology, Chia Nan University of Pharmacy and Sciences, Tainan 717, Taiwan Department of Anesthesiology, Chi-Mei Medical Center, Tainan 710, Taiwan Department of Medical Research, Chi-Mei Medical Centre, Tainan 710, Taiwan


In this paper, the capacity of four-month-old infants from monolingual environments to distinguish between two syllable-timed languages is analysed. Catalan and Spanish are both Romance languages which present differences at the segmental level and at the syllable structure level, but show important similarities concerning prosodic structure at the phonological phrase level. Nevertheless, the presence of vowel reduction only in Catalan may determine rhythmic differences which could be detected by infants and used to tell these two languages apart. Two experiments have been run, with normal and low-pass filtered utterances, using a visual orientation procedure with a reaction time measure. Results indicate that infants are able to discriminate even when segmental information has been removed. The distinction seems to be the result of basic differential rhythmic properties between these two languages.


We describe the case of a 27-year-old male with painful lymphadenopathy involving multiple sites. An excisional lymph node biopsy established the diagnosis of Kikuchi-Fujimoto disease (KFD) and the patient improved with supportive care only and did not have further episodes. This is a case of a rare, benign lymphadenitis, of unknown etiology. The histopathology proved the benign character of the lymphadenopathy and made the diagnosis clear, despite the nonspecific character of the clinical presentation. It is important to recognize the clinical and histopathological aspects of KFD in order to avoid unnecessary and sometimes harmful treatment, such as chemotherapy, when this disease is confounded with lymphoma.


An estimated 6.5 million Americans aged 65 years or older have Alzheimer's disease (AD), which will grow to 13.8 million Americans by 2060. Despite the growing burden of dementia, no fundamental change in drug development for AD has been seen in > 20 years. Currently approved drugs for AD produce only modest symptomatic improvements in cognition with small effect sizes. A growing mismatch exists between the urgent need to develop effective drugs for symptomatic AD and the largely failed search for disease modification. The failure rate of clinical trials in AD is high overall, and in particular for disease-modifying therapies. Research efforts in AD have focused predominantly on amyloid-β and tau pathologies, but limiting clinical research to these "classical hallmarks" of the disease does not address the most urgent patient, caregiver, or societal needs. Rather, clinical research should consider the complex pathophysiology of AD. Innovative approaches are needed that provide outside-the-box thinking, and re-imagine trial design, interventions, and outcomes as well as progress in proteomics and fluid biomarker analytics for both diagnostics and disease monitoring. A new approach offering a highly specific, yet multi-pronged intervention that exerts positive modulation on the HGF/MET neurotrophic system is currently being tested in mid-to-late-stage clinical trials in mild to moderate AD. Findings from such trials may provide data to support novel approaches for development of innovative drugs for treating AD at various disease stages, including among patients already symptomatic, and may offer benefits for other neurodegenerative diseases.


Atomic force microscopy (AFM) was employed to investigate the nanostructure of the catfish (Ictalurus punctatus) skin gelatin aggregates. The gelatin was extracted at an optimized acid after alkaline processed condition. First, the imaging parameters were optimized for obtaining high quality AFM images. Then height and error signal mode images were used for sectional profile analysis and particle analysis. The results illustrated the fish gelatin at nano scale, compared with those AFM images of gelatins. Both circular pores with the diameters of 117.6 nm and spherical aggregates with the average diameter of 266.9 nm were found in AFM images. We proposed that the penetration way of water and ionic during hydrolyze the collagen determined the structure formed and a scheme for the formation of annular pores and spherical aggregates is proposed. The AFM results would help researchers to better understand the structure and further its functional properties, the nanostructural results could be applied to improve the physical properties of fish gelatin.


OTTAWA-- Canadian health officials are seriously considering a plan that could double federal spending on university-based medical research next year by creating a national framework that would supplement the current bottoms-up approach to funding research. Such a system would give the ruling Liberal government a way to invest in health care without stepping on the jurisdictional toes of the provinces and to inject $375 million a year into a biomedical and health research community now strapped for cash.


Different Cu/(Mg or Ni)/Al mixed oxides based on hydrotalcite-like compounds have been studied for the catalytic oxidation of trichloroethylene. The catalysts have been synthesized and characterized by different techniques such as N2-adsorption, inductively coupled plasma (ICP), X-ray diffraction, and temperature-programmed reduction (TPR). It has been shown that the activity for the catalytic abatement of trichloroethylene depends on the presence of metals with redox properties in the catalyst composition. The best results have been obtained with containing copper mixed oxides, although there is no direct correspondence between the copper content and the catalyst activity. These catalysts are highly active and selective, CO2 and HCl being the main reaction products. A mechanism for the reaction has been proposed.


The Boltzmann transport equation can be solved to give analytical solutions to the resistivity, Hall, Seebeck, and Nernst coefficients. These solutions may be solved simultaneously to give the density-of-states (DOS) effective mass, the Fermi energy relative to either the conduction or valence band, and a scattering parameter that is related to a relaxation time and the Fermi energy. The Nernst coefficient is essential for determining the scattering parameter and, thereby, the effective scattering mechanism(s). The authors constructed equipment to measure these four transport coefficients simultaneously over a temperature range of 30-350 K for thin, semiconducting films deposited on insulating substrates.


Introduction: Local Anaesthetic Thoracoscopy (LAT) has a role in the work-up of undiagnosed pleural effusions. If non-expandable lung is suspected, an indwelling pleural catheter (IPC) can be inserted at LAT. Incidence of subcutaneous emphysema (SCE) following this is unclear. It is unknown whether SCE reduces when the IPC is placed through a separate incision to the thoracoscopy port. We aim to establish the incidence of SCE when IPC is placed at time of rigid LAT and whether the site of IPC insertion influences this. Methods: Retrospective analysis of LAT electronic records and chest radiographs over a six-year period was undertaken at a tertiary centre. SCE was assessed at day 1 and discharge imaging and graded 0-4 [0 none; 1 IPC site; 2 ipsilateral chest wall; 3 neck; 4 contralateral chest wall]. Results: Between 2014-2019, there were 36 dual LAT and IPC procedures. Median length of stay post-LAT was 3 days. 28 patients had IPC sited through the LAT port incision and 8 were sited through a separate incision. Incidence of any subcutaneous emphysema on day 1 was 22/28 (79%) through port site and 4/8 (50%) through separate incision. At discharge, incidence was 79% and 62% respectively. No patients required additional intervention. Combined incidence of subcutaneous emphysema of Grade ≥2 only occurred in 10/36 (27%) on day 1 and 13/36 (36%) at discharge. For patients with IPC via separate incision, incidence of Grade ≥2 was 12.5% and 25% respectively compared with 32% and 40% for IPCs via LAT port site. Conclusions: Placement of IPCs through a separate incision to the LAT site may reduce the incidence of subcutaneous emphysema in rigid LAT.


Citrullus colocynthis is an important medicinal herb belonging to family cucurbitaceae. Plants are efficient chemical factories that produce a wide variety of chemical compounds called phytochemicals. Two types of metabolites are produced from plants i.e. primary metabolites viz., carbohydrates, lipids etc. and secondary metabolites viz., alkaloids, flavonoids, essential oils, sterols, lignin and tannins. In the present set of investigations, biochemical changes of various cellular metabolites/enzymes were observed from in vivo (leaf, stem, fruit and root) and in vitro (callus and differentiating callus) of Citrullus colocynthis. Result showed that the total phenolic contents were maximum in leaf sample and minimum in differentiating callus. Ortho-dihydroxy phenolic contents were maximum in differentiating callus and minimum in leaf. High polyphenol oxidase activity was observed in differentiating callus and minimum in leaf sample.


Fairness measure is used in designing Operating System (OS) schedulers to determine whether users or applications are receiving a fair share of system resources. PS (proportional share) schedulers are the dominant schedulers in Virtual Machine (VM) environment. A PS scheduler assigns a weight to every VM to allocate CPU cycles, allocating these cycles to VM is proportional to that weight. Current VM scheduling algorithms don't aware about the attributes (e.g. weights and number of threads) of the running processes in VMs. We illustrate this issue through experimental evaluations of the current scheduling thus revealing its weakness. A modification of current scheduler is proposed in this work to enable users to specify weights to VMs. Therefore, user gets CPU usage proportion to the assigned weight, the higher weight the more CPU usage and vice versa. In addition, a pricing calculator is considered to calculate the fee that the user should pay according to his desired CPU usage. Derived results show that our modification achieves accurate proportional fairness for a diverse set of workloads.


and controls. Mean RSN spatial maps for all 50 subjects are shown using hot colours. Regions of significant group differences (p < 0.01) are shown in cold colours. DMN = Default mode network, RFP = Right fronto-parietal, LFP = Left frontoparietal, Vis = Visual, SM+Aud = Sensorimotor and auditory, PF = Pre-frontal. MNI coordinates (mm) shown for slice locations. A resting-state fMRI study in chronic obstruction pulmonary disease Ai Wern Chung, James W. Dodd, Rebecca A. Charlton, Paul W. Jones, and Thomas R. Barrick Stroke and Dementia Research Centre, St George's University of London, London, London, United Kingdom, Division of Clinical Science, St George's University of London, London, United Kingdom, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, United States


In order to further improve the population diversity of the immune cloning algorithm when optimizing high-dimensional objects, and to improve the algorithm's global optimization ability and search efficiency, an immune cloning optimization algorithm based on antibody similarity screening and steady-state adjustment (ICASA) is proposed. By screening, that is, removing highly similar antibodies in the antibody population, the probability of the algorithm searching for the optimal solution is improved, and the repeated solution of similar antibodies is avoided. The antibody population is adjusted based on themedian property, and is injected with a high-quality vaccine realized by the median, which makes the antibody population evenly diffuse in the solution space to generate global antibody solutions. Finally, the convergence of the algorithm is proved by Markov chain theory. The test results of six groups of high-dimensional functions show that, compared with genetic algorithm (GA), immune cloning algorithm (ICA) and immune genetic algorithm (IGA), the proposed algorithm achieves 100% optimization, and the minimum convergence algebra, average convergence algebra and iterative algebra standard deviation are reduced by an average of 13.3%, 5.3%, and 29.3%, respectively, which verifies the algorithm's strong optimization ability, fast convergence and good stability.


The invention discloses an automatic opening and closing notebook computer, which comprises a host, an upper cover and a rotating device connected to the host and the upper cover. An on-off key is arranged on the lateral part of the host and connected with an internal power supply of the notebook computer. The rotating device comprises a rotating bracket, a positioning rotating shaft, an angle gasket and a fixed bracket, wherein one end of the rotating bracket is fixed on the upper cover of the notebook computer; a positioning hole and a positioning column are arranged on the other end face of the rotating bracket; the positioning rotating shaft is matched with the positioning hole; the angle gasket is matched with the positioning column; and one end of the fixed bracket is fixed on the host of the notebook computer, and the other end of the fixed bracket is matched with the rotating bracket and the angle gasket by a driving device. The automatic opening and closing notebook computer can be automatically opened and closed, is easy to operate and solves the problem of conventional complex operations.


In undertaking strategic water resources planning for Melbourne, a range of scenarios of future water availability from existing water supply assets and the future demand for water have shown that the timing of future imbalances in water supply and demand is very uncertain. This is due to compounding uncertainties in future climate conditions, population growth, water use behaviour, and a range of other factors. This uncertainty makes it difficult to identify a fixed schedule of supply and demand actions over the long-term. As a result adaptive management principles were developed through a Water Outlook (WO) approach. The WO is published annually on 1st December to review the storage level at the end of November each year with reference to three water security zones: High, Medium and Low zones. The WO proposes an appropriate mix of supply-demand actions that should be undertaken during the following years to provide for water security. This paper describes a risk-based modelling approach to derive the action points, expressed in terms of the volume of water available in storage, to define the three water security zones for Melbourne. The innovative approach made use of a database of storage drawdown simulations under a wide range of possible drought inflow conditions generated using Melbourne's REALM headworks system model. This has enabled rapid screening of the database to derive the action points by exploring a range of possible critical drought risks and durations. The action points derived were tested under a range of potential extreme drought inflow scenarios and a continuation of dry conditions experienced during the recent 1997-2009 'Millennium drought'. The risk-based modelling approach is technically sound and practically robust to guide water security management and was incorporated in the drought response planning for Melbourne.


BACKGROUND
The objective of the study was to investigate whether radiotherapy or its omission after breast-conserving surgery has measurable consequences on local tumor growth and patient survival.

METHODS
We conducted a pooled analysis of published randomized clinical trials that compared radiotherapy versus no radiotherapy after breast-conserving surgery. The outcomes studied were ipsilateral breast tumor recurrence and patient death from any cause. The pooled relative risks (RRs) were estimated with a random-effects model. Heterogeneity was assessed using the Cochran Q test.

RESULTS
A search of the literature identified 15 trials with a pooled total of 9422 patients available for analysis. The relative risk of ipsilateral breast tumor recurrence after breast-conserving surgery, comparing patients treated with no radiotherapy or radiotherapy, was 3.00 (95% confidence interval [CI] = 2.65 to 3.40). Mortality data were available for 13 trials with a pooled total of 8206 patients. The relative risk of mortality was 1.086 (95% CI = 1.003 to 1.175), corresponding to an estimated 8.6% (95% CI = 0.3% to 17.5%) relative excess mortality if radiotherapy was omitted.

CONCLUSION
Omission of radiotherapy is associated with a large increase in risk of ipsilateral breast tumor recurrence and with a small increase in the risk of patient mortality.


Abstract Continuous subcutaneous (SubQ) treprostinil is an effective therapy for pediatric patients diagnosed with pulmonary hypertension (PH). To date, the clinical characteristics and factors associated with failure to tolerate this therapy have not been described. The purpose was to describe patient‐reported factors contributing to SubQ treprostinil intolerance in pediatric patients with PH. A retrospective descriptive study was performed at 11 participating sites in the United States and Canada for patients younger than 21 years of age diagnosed with PH who failed treatment to tolerate SubQ treprostinil between January 1, 2009, and December 31, 2019. All data were summarized using descriptive statistics. Forty‐one patients met the inclusion criteria. The average age at SQ treprostinil initiation, and length of treatment, was 8.6 years and 22.6 months, respectively. The average maximum dose, concentration, and rate were 95.8 ng/kg/min, 6.06 mg/mL, and 0.040 mL/h, respectively. The reasons for failure to tolerate SubQ treprostinil included intractable site pain (73.2%), frequent site changes (56.1%), severe site reactions (53.7%), infections (26.8%), and noncompliance/depression/anxiety (17.1%). Thirty‐nine (95.1%) patients transitioned to a prostacyclin therapy with 23 patients transitioning to intravenous prostacyclin, 5 to inhaled prostacyclin, 5 to oral prostacyclin, and 7 to a prostacyclin receptor agonist. A subset of pediatric PH patients failed to tolerate SubQ treprostinil infusions despite advances in SubQ site maintenance and pain management strategies. Intractable site pain, frequent SubQ site changes, and severe localized skin reactions were the most common reasons for failure.


There is always the matter of a surplus that comes from an elsewhere and that can no more be assimilated by me, than it can domesticate itself in me. A teaching that may part ways with Heidegger's motif of our being able to learn only what we already understandwhen does learning take place? what do we already understand?the Conversation belongs, as ethical relation, to the effort of thinking the infinite, the transcendent, the Stranger. None of this amounts to thinking an object. Avital Ronell, Dictations


An effective scheme is proposed for preparing large-scale maximally entangled W states by fusing arbitrary-size polarization entangled W or W-like states via polarization-dependent beam splitter (PDBS). In our scheme, Wm+n−1 state can be generated from an n-qubit W state and an m-qubit W state, and Wm+n+t−2 state can be generated from Wm, Wn and Wt states. The fusion process can start with Bell states too. Because PDBS has selective transmission rates for different polarization states, our fusion has a distinct property, i.e. a large-scale maximally entangled W state can be generated by fusing small-size W-like states, and the cost analyses indicate that our fusion scheme is more efficient than the previous one in fusing W-like states. In addition, there is no need for any controlled quantum gate and any ancillary photon in our scheme, so it is simple and feasible.


People often struggle to find appropriate energy-saving measures to take in the household. Although recommender studies show that tailoring a system's interaction method to the domain knowledge of the user can increase energy savings, they did not actually tailor the conservation advice itself. We present two large user studies in which we support users to make an energy-efficient behavioral change by presenting tailored energy-saving advice. Both systems use a one-dimensional, ordinal Rasch scale, which orders 79 energy-saving measures on their behavioral difficulty and link this to a user's energy-saving ability for tailored advice. We established that recommending Rasch-based advice can reduce a user's effort, increase system support and, in turn, increase choice satisfaction and lead to the adoption of more energy-saving measures. Moreover, follow-up surveys administered four weeks later point out that tailoring advice on its feasibility can support behavioral change.


Objective To evaluating the promote effect of a Pro-ABB yogurt on physical intestinal canal. Methods The trial was a 3-week randomized trial on 200 healthy person aged from 25 to 45 years 1:1 gender randomly to 4 groups: blank group, ordinary yogurt group, 1 yogurt group, 2 yogurt group. Each group intake the corresponding yogurt 100 g twice everyday respectively on 10 a.m. and 4 p.m. except for blank group. Results 1.Effectively improve digestive system on abdominal distension, bellyache, gastrectasia, stomach ponderosity, inappetency. 2. Effectively improve digestive canal health. 3. Effectively increase satisfaction on defecate frequency, defecate period, feces trait, defecate habit. 4. Effectively improve weekly defecate frequency and feces weight. Conclusions Significant effectiveness on slightly constipation and GI symptom were proved by intake Pro-ABR probiotics yogurt.


Organophosphorus(OP) compounds which are widely used as high efficient and broad-spectrum insecticides caused broad-area pollution to environment.A bactrium with high efficient capability of degrading methyl parathion,identified as Ochrobactrum sp.by 16S rDNA analysis,is isolated from highly OP-polluted soil in this study.The full-length mphxw gene from this bactrium is cloned by PCR.The prokaryotic expression vector is constructed and the expressed products bore normal bioactivity in E.coli.The methyl parathion hydrolase MPD is purified.


This article is an investigation of the agency of matter and an exposition of the new materialist methods I have been developing as part of a muti-sited trans-national ethnography that features socially engaged arts practices alongside more traditional ethnographic and qualitative techniques. I think through the agency of matter and consider the temporality of matter as part of its agency, understanding these agents as constitutive features of the research assemblage. Drawing on ethnographic fieldwork from the United Kingdom, I examine how matter's space-time can impact processes of making the social. I develop theoretical resources for moving the field forward.


Plasma-generated hydroxyl radicals (·OH) and oxygen atoms (O) produced by the COST reference plasma jet, a micro-scaled atmospheric pressure plasma jet, were investigated using a variety of experimental techniques. Several gas admixtures were studied to distinguish the contributions of the two reactive oxygen species. Large discrepancies between inferred aqueous ·OH densities were noted when using a 2-hydroxyterephthalic acid (HTA) fluorescence assay and electron paramagnetic resonance (EPR) measurements with the spin trap 5,5-dimethyl-1-pyrroline N-oxide—especially when oxygen was present in the feed gas. A series of follow-up experiments including optical emission spectroscopy, H2O2 quantification, and EPR measurements of atomic oxygen using the spin trap 2,2,6,6-tetramethylpiperidine, revealed that the inconsistencies between the measured aqueous ·OH were likely due to the propensity of atomic oxygen to hydroxylate TA in a manner indistinguishable from ·OH. This renders the HTA assay non-selective when both ·OH radicals and atomic oxygen are present, which we report for all three gas admixtures in our experiments. Additionally, considerable degradation of both HTA and the spin adducts measured using EPR spectroscopy was apparent, meaning actual radical densities in the plasma-treated liquid may be considerably higher than implied. Degradation rates compared favorably to previously measured gas phase densities of atomic oxygen in the predecessor of the COST jet and reported degradation of other chemical probes. These results show the prolific role of atomic oxygen in plasma-induced liquid chemistry and caution against diagnostic techniques that are unable to account for it.


Coin flipping is a cryptographic primitive in which two spatially separated players, who in principle do not trust each other, wish to agree on a random bit. Classical and quantum coin flipping protocols have been studied extensively for more than twenty‐five years. However, until recently, quantum coin flipping protocols were designed without taking into consideration the losses of quantum information that would be unavoidable in any realistic implementation. We introduced in 2008 a novel protocol and proved its security even when losses are taken into account: no cheating player could obtain a desired outcome with a probability greater than (6+2)/8≈93%. Here, we refine our earlier protocol by making it fair in the sense that the optimal cheating strategies allow either player to bias the outcome by the same amount. Specifically, either player can cheat to obtain a desired outcome with probability exactly 90%, but no more. An implementation is underway.


We use lattice simulations to compute the baryon spectrum of SU(4) lattice gauge theory coupled to dynamical fermions in the fundamental and two-index antisymmetric (sextet) representations simultaneously. This model is closely related to a composite Higgs model in which the chimera baryon made up of fermions from both representations plays the role of a composite top-quark partner. The dependence of the baryon masses on each underlying fermion mass is found to be generally consistent with a quark-model description and large-Nc scaling. We combine our numerical results with experimental bounds on the scale of the new strong sector to derive a lower bound on the mass of the top partner.


We present in Table I an updated list of the sensitivities of 298 restriction endonucleases and 20 DNA methyltransferases to sitespecific modification at 4-methylcytosine ("HT), 5-methylcytosine C^C), 5-hydroxymethylcytosine OTM^), and 6-methyladenine (^A) (McC14), four modifications that are common in the DNA of prokaryotes, eukaryotes, and their viruses (Mc2,Mc5,Mc8,Mcll,Ne3,Ne4). In addition, new information is included on restriction endonuclease cleavage at sites modified with 5-hydroxymethyluracil ( ^ U ) . Knowledge of the sensitivity of restriction endonucleases to site-specific modification can be used to study cellular DNA methylation. Several restriction-modification enzymes share the same recognition sequence specificity, but have different sensitivities to site-specific methylation. Table II lists 32 known isoschizomer pairs and one isomethylator pair, along with the modified recognition sites at which they differ. The data presented here and an additional three other tables are available in printed form or as a text file on a 3.5" Macintosh diskette. The extra tables include Table HI which is a list of over 205 characterized DNA methyltransferases. A detailed list of cloned restriction-modification genes has been made by Wilson (Wi4). Table IV lists the sensitivities of over 20 Type II DNA methyltransferases to "^C, C, C, and "^A modification. Most DNA methyltransferases are sensitive to non-canonical modifications within their recognition sequences (Bu9,MclO, Ne3,Po4), and this sensitivity often differs from that of their restriction endonuclease partners. Table V gives a list of restriction systems in this review alphabetized by recognition sequence. The data can be supplied as a Microsoft Word, Macwrite or MS-DOS file. Please contact Michael McClelland at CTBR, phone 619 535 5486, FAX 619 535 5472.


Regional Cardiothoracic Centre, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, U.K. Antiarrhythmic drugs play a small but important part in the long-term management of patients following myocardial infarction. Mexiletine, disopyramide and amiodarone seem the three most valuable drugs in this context at present. Indications for therapy are not clearly defined except in patients who are symptomatic or who have repetitive ventricular tachycardia and fibrillation. Introduction


Adolescence phase comprises between 10 and 19 years old. This stage is characterized by a fast individual growth and development. However, these changes do not occur at the same rate for both genders, and can lead to differences in postural balance. The purpose of this study was to compare the postural balance between male and female adolescents. To this, 11 female and 19 male adolescents were assessed. The center of gravity height was obtained by a reaction board, and postural balance was evaluated with a force platform from Advanced Mechanical Technologies, Inc. model OR6-6. The variables analyzed were calculated from the center of pressure (COP): COP anteroposterior range of displacement (COPap), COP mediolateral range of displacement (COPml); and COP mean displacement velocity (COPvel). Female adolescents showed a significantly lower COPap (p=0.011) and COPml (p=0.003) ranges of displacement with open eyes when compared to male adolescents. With closed eyes, females had lower COPap (p=0.001), COPml (p=0.001) and COPvel (p=0.004). It suggests a lower postural sway for these female adolescents. It is believed that the results came from differences in anthropometric characteristics between genders. We conclude that female adolescents in this study had a better postural balance when compared to male adolescents.


Background: The specific properties of a synapse determine how neuronal activity evokes neurotransmitter release. Evaluating changes in synaptic properties during sustained activity is essential to understanding how genetic manipulations and neuromodulators regulate neurotransmitter release. Analyses of postsynaptic responses to high-frequency stimulation have provided estimates of the size of the readily-releasable pool (RRP) of vesicles (N0) and the probability of vesicular release (p) at multiple synapses. New method: Here, we introduce a model-based approach at the calyx of Held synapse in which depletion and the rate of replenishment (R) determine the number of available vesicles, and facilitation leads to a use-dependent increase in p when initial p is low. Results: When p is high and R is low, we find excellent agreement between estimates based on all three methods and the model. However, when p is low or when significant replenishment occurs between stimuli, estimates of different methods diverge, and model estimates are between the extreme estimates provided by the other approaches. Comparison with other methods: We compare our model-based approach to three other approaches that rely on different simplifying assumptions. Our findings suggest that our model provides a better estimate of N0 and p than previously-established methods, likely due to inaccurate assumptions about replenishment. More generally, our findings suggest that approaches commonly used to estimate N0 and p at other synapses are often applied under experimental conditions that yield inaccurate estimates. Conclusions: Careful application of appropriate methods can greatly improve estimates of synaptic param-


The utility model relates to a weighing machine using fluid pressure to transmit buffering. The center of a weighing platform is connected with a touch pin, and the bottom end of the touch pin is contacted with one hydraulic cylinder. Hydraulic cylinders are assembled in a main hydraulic cylinder via tube strips and the distributing tubes of tube joints, and a probe which is contacted with an electronic inductor is extended out from the main hydraulic cylinder. The hydraulic cylinders are composed of cylinders, casing covers and shims, and then all hydraulic cylinders are connected into a closed hydraulic system via the distributing tubes. The force of the weighing platform after stressed can be transmitted in a state without friction according to the pascals law, errors can be reduced, and the measuring accuracy of the weighing machine can be improved.


This chapter introduces the reader to the concept of genetics and disease and includes review of more than 200 family, twin, and adoption studies for six important mental and behavioral disorders. The heritability estimates range from 30% for depressive disorder to as high as 80% for schizophrenia. Genome-wide association and sequencing studies are beginning to identify genetic risk variants associated with these disorders, but a large proportion of the genetic contribution remains unexplained. Major challenges in genetic studies include defining and agreeing on the phenotype that should be the subject of the study and the apparent complexity of the genetic etiology. In the near future, as larger samples with more detailed phenotype information are studied, a clear picture of the underlying genetic architecture of mental and behavioral disorders will emerge.


Objective To investigate the related factors and quality of life in the female patients with primary overactive bladder (OAB) to provide the basis for the chnical treatment.Methods One hundred and seven female patients with primary OAB were surveyed by the questionnaire about the general data and the King' s Health Questionnaire (KHQ),and the correlation was analyzed by the Spearman.Results The occurrence of female patients with primary OAB was related to the age,marital status,mode of delivery,dehvery times,body mass index,with and without chronic diseases (P < 0.05),and was not related to the education,residential area,abortion and diet habits (P > 0.05).The scores of the general health feeling,the severity of voiding problem,the restricted behavior,restricted motion,social limitations,the personal life,emotion,sleep and energy,the coping style of symptoms,and severity of symptom in KHQ were respectively (61.44 ± 14.68),(81.31 ±26.76),(32.54±28.63),(46.73 ±21.27),(27.91 ±23.75),(20.91 ±25.86),(47.90 ± 28.19),(32.40 ± 23.44),(14.49 ± 17.02),and (8.45 ± 2.69).The score of Overactive Bladder Syndrome Score (OABSS) was positively correlated with the severity of voiding problem,restricted motion,social limitations,emotion,the coping style of symptoms and the severity of symptom (r =0.280,0.334,0.288,0.224,0.325,0.458,respectively; P<0.05).Contusions The symptoms of female patients with primary OAB are related to the age,marital status,delivery times,body mass index,with and without chronic diseases,and OAB can affect the patient' s quality of life in different degrees.

Key words:
Quality of life;  Risk factor;  Overactive bladder;  Female


The life-span of this project (short title Multiple Livelihoods and Social Change) was 1 April 1998 to 31 March 2001. The original end-date of 31 March 2000 was extended firstly by an additional six months of employment for the research officer (Rachel Slater) and secondly by a request for a further period of six months in which the director (Colin Murray) and principal collaborator (Elizabeth Francis) could consolidate the writing-up of research materials.


The aim of this project is the study of viability of a heat exchanger application for a determinate type of building. The type of building selected is a sportive complex, where its water consumption conditions will be important for making the analysis of a double pipe heat exchanger and for defining the possible performance of equipment. Is wanted to make a full study of the effect of the diverse parameters on the final performance and an estimative cost and amortization of the equipment.


Objective The paper was to explore the characteristics of committing an offence between patients with major depression and other depressive disorders Methods A comparative study was conducted between 37 cases with major depression and 31 cases with other depressive disorders (15 with psychogenic depressive disorder, 9 with depressive neurosis, 7 with depressive personality) from 1980 to 2000 Results In major depression group, the behavior of committing an offence was abrupt and random (62%), and lack of inducement (76%) Most of them had pathological motivation (54%) and committed homicide and injury (76%), in which their family was more often attacked (54%) Thirty eight of the patients attempted to commit suicide after the offence In other depressive disorder group, many of them had inducement (55%), escaped from the scene after the case occurred (45%), defended for the offence (38%) and required for forgiveness (34%) As to the above characteristics, there was significant difference ( P 0 05) between the two groups Conclusion There are different characteristics of committing an offence between the patients with major depression and those with other depressive disorder The difference may be associated with the different pathogeny, state of an illness and psychotic symptom


Autopsy investigations of experimentally produced vascular displacements by stereotaxic methods have been suggested as a means of arriving at an improvement in the location of posterior fossa lesions (GREITZ et colI., to be published). This implies as a technical prerequisite that postmortem angiography of the posterior fossa be performed with the skull essentially intact. Earlier investigations dealing with postmortem cerebral angiography have been mostly based on a non-selective technique or on selective injections in isolated autopsy specimens (MONIZ 1940, KAPLAN 1953, 1956, VANDER EECKEN & ADAMS 1953, HUTCHINSON & YATES 1956, JOHNSON & YATES 1956, STEIN et colI. 1962, RODDA & DUGDALE 1963, MATSUDA 1964, SVARE et colI. 1964, WOLLSCHLAEGER & WOLLSCHLAEGER 1966, STEPHENS & STILWELL (1969). A technique of selective postmortem vertebral angiography of the intact skull does not seem to have been published. HAUGE (1954), GALLOWAY & GREITZ (1960) and GREITZ & SJOGREN (1963) carried out selective angiographies of the vertebral artery in cadavers, the skull being opened to ligate the posterior communicating arteries. A similar method was used by HASSLER (1967 a) for


This article examines the intraday price discovery process among stock index, index futures, and index options in Germany using DAX index securities and intraday transactions data. The three index securities contribute to a common factor, but the spot index and index futures have substantially larger information shares than index options. Moreover, the returns of the three index securities exhibit feedback effects, with futures being dominant. Because the trading costs of the futures appear to be the lowest of the three and those of the options to be the highest, the results are consistent with the transaction cost hypothesis. © 1999 John Wiley & Sons, Inc. Jrl Fut Mark 19: 619–643, 1999


We address the problem of recognizing offensive play strategies from American football play videos. Specifically, we propose a probabilistic model which describes the generative process of an observed football play and takes into account practical issues in real football videos, such as difficulty in identifying offensive players, view changes, and tracking errors. In particular, we exploit the geometric properties of nonlinear spaces of involved variables and design statistical models on these manifolds. Then recognition is performed via 'analysis-by-synthesis' technique. Experiments on a newly established dataset of American football videos demonstrate the effectiveness of the approach.


This paper uses the approach of Adams, Gray & watkins ( 1971 ) to provide an asymptotic rationalisation for the bias reducing property of the jackknifed two stage least squares (J2SLS) estimator observed by Mikhail ( 1975 ).


The Youth Project of the Centre for Conflict Resolution (CCR)-formerly known as the Centre for Intergroup Studies, an autonomous institute associated with the University of Cape Town-focuses on the field of constructive conflict resolution and peacemaking empowerment for young South Africans and is one of the pioneers in this field in South Africa. In 1992, the Human Sciences Research Council initiated a cooperative research program into South African youth and the problems and challenges they face. Among the program objectives were the initiation and support of research into South African youth, and the generation of academically sound research results with significant policy implications. CCR was commissioned to participate and submit a report titled "Conflict Resolution and Peacemaking Among Youth." The report was


Here, we review the definition of a 1-form gauge field. Mathematically, a 1-form gauge field with gauge group G = U(1) is a connection onM×G (or more generally a G-bundle E →M), whereM is the spacetime manifold. [1, 2]. This can be made more explicit by considering a good open cover of the spacetime manifold M; i.e. consider a collection of sets Ui ⊂M that coverM (i.e. ∪iUi =M) such that finite intersections Ui1 ∩ Ui2 ∩ · · · ∩ Uin are diffeomorphic to an open ball. A 1-form gauge field can then be specified by the following data and constraints [3]: (1) The gauge field is locally defined on each Ui by a 1-form A(i). 1 (2) On nonempty overlaps Ui∩Uj (depicted in yellow below), the two locally defined fields A(i) and A(j) must be equal up to a gauge transformation:


In Education Policy Gorard takes us on a lively journey through 20 years of his own (and colleagues') education research. This new text provides an important and accessible synthesis of evidence re...


Marked changes in the occurrence and quality of near-surface ground water in Las Vegas Valley, Nevada result from urban and industrial land and water use practices. In-valley recharge has increased tenfold in the period 1943 to 1973 and now amounts to about 40,000 acre-feet/year (49.3 million m3). Ground-water flows leaving the Valley have increased from 250 acre-feet/year to about 12,000 acre-feet/year.

Twenty to 400 tritium units (T.U.) in shallow ground water confirm widespread addition of recent recharge. Trend-surface analysis of recent water-quality data for depth intervals or "slices" of 0 to 50, 51 to 100, and 101 to 300 feet (0 to 15.2 m, 15.5 to 39.5 m, 30.8 to 91.4 m) revealed that natural trends below a depth of 50 feet are explainable in terms of broad hydrogeologic conditions. From 0 to 50 feet quality is highly irregular and markedly more influenced by land and water use practices and waste disposal in particular. Chloride, TDS, and nitrate are particularly diagnostic of return flows as is spring development and (or) a rising water table resulting from increased recharge and low vertical permeability. Statistical tests on water-quality data for the period 1912 to 1968 yielded generally insignificant change with time. However, the extreme paucity of the data base makes any conclusion questionable.

More efficient irrigation practices could reduce the present irrigation water demand by 15,000 acre-feet/year and reduce return flows by 11,000 acre-feet/year. Return flows by the year 2000 could easily amount to 75,000 acre-feet/year or about three times the total water budget of the Valley prior to urbanization. Therefore, groundwater problems are likely to worsen and, if present monitoring practices prevail, go unnoticed.


Using texture analyzer,the gels of carrageenan and agar were measured.Special attention was pain to the influence of concentration,pH value and Mg2 +ion intensity on the gel strength of the agar and carrageenan.The results showed that the gel strength of the agar have a small increasing trend with the increase of the concentration of Mg2 +,so Mg2 +can be added to the agar.But Mg2 +can not make carrageenan gel effectively,the concentration was the main factor in affecting the gel strength.This strength increased with increasing concentration,and firstly increased and then decreased with the increase of pH value.


Since the 1970s, international students have represented a growing proportion of the global student body, yet how they adjust and how universities can support them is relatively unexplored. We conducted a qualitative study of 36 international students of 11 nationalities studying in Norway and the UK and found that their experience did not fit the dominant 'U-Curve' of adaptation that suggests there is a honeymoon period on arrival. Confirmed with conversations with student wellbeing staff, who suggest that anxiety and culture shock are the norm, the data allows us to suggest factors that trigger adjustment and interventions to improve students' experience. Our contribution is a 'J-Curve' model comprising cultural challenge, adjustment, and mastery, to reflect the reality of the  international student experience.


Measurement results showing intensity vector reconstructions using a rigid spherical microphone array in a vehicle cabin are presented. The measurement equipment developed by Nittobo was used in previous demonstrations to visualize the acoustic field using a beamforming technique superimposed on a picture from an on‐board camera. In the present study intensity reconstructions are shown and are successful in locating and quantifying sources, demonstrating the usefulness of this technique in an enclosed space like a vehicle cabin, aircraft cabin, small room, etc. This work was supported by the US Office of Naval Research and Nittobo Acoustic Engineering Co. Ltd.


This study is a retrospective analysis of data stored digitally for 13 years in a Vision Center located in the urban area of Tirana, Albania. In a population of 19,686 people (39.5% M and 60.5% F) who met the criteria, there was a prevalence of astigmatism 42% (12% only astigmatism, 30% associated with hyperopia or myopia), myopia 25%, hyperopia 22% and 24% presbyopic prescriptions for the medium and near distance. The myopia progression study (mean spherical equivalent) indicates that 20% of people had no change, 42% had an increase in myopic correction from 0.25D to 0.50D, 17% from 0.75D to 1.00D, 11% from 1.25D to 1.50D, 5% from 1.75D to 2.00D and 5% of the population had myopic progression greater than 2.00D.


We present a method for hyper-spectral characterization of the nonlinear effects in a tunneling junction. Harmonics up to 1 GHz were measured in a frequency comb in the tunneling current when 15-fs laser pulses at a repetition rate of 74.25 MHz were focused on the tunneling junction of a scanning tunneling microscope. The typical output power is −120 dBm at the fundamental frequency, which is the pulse repetition rate and decreases by several dB for the higher harmonics. The observed square-law dependence of the signal power on the tunneling current and incident laser power is in good agreement with theoretical predictions.


Special-purpose cement is produced to fit for the structural and constructive characteristics of Shi-banpo Yangtze multiple track bridge.Through controlling mineral consistence and hydration heat of the special purpose cement,it can reduce the temperature rising,improve the volume stability and durability of concrete directly and effectively.By using the special-purpose cement,HPC possesses good synthetic technical performance.


Laptop and desktop computers are frequently used to watch online videos from a wide variety of services. From short YouTube clips, to television programming, to full-length films, users are increasingly moving much of their video viewing away from television sets towards computers. But what are they watching, and when? We set out to understand current video use on computers through analyzing full browsing histories from a diverse set of online Americans, finding some temporal differences in genres watched, yet few differences in the length of videos watched by hour. We also explore topics of videos, how users arrive at online videos through referral links, and conclude with several implications for the design of online video services that focus on the types of content people are actually watching online.


Sheep anti-rat-kidney serum and rabbit anti-rat-kidney serum were utilized in a number of biological studies in order to clarify some of the qualitative and quantitative effects of this antiserum. The teratogenic factor or factors present in these antisera can be characterized as follows: The antiserum is (1) ineffective when administered by the oral route; (2) the antiserum is teratogenic when administered by the intravenous, intraperitoneal, subcutaneous or intrauterine route; (3) more effective by the intravenous and intraperitoneal route than by the subcutaneous route and (4) no more effective when injected into the uterine lumen of a pregnant rat than when given intravenously; (5) uterine vascular clamping experiments and injection of the antiserum during the preimplantation period indicate that the teratogenic milieu persists for days following the administration of the antiserum; (6) the antiserum can be considered a classical teratogenic agent because it produces a different spectrum of malformations on different days of gestation and concomitant fetal mortality and growth retardation; although stage specificity is not as dramatic with the antiserum as with irradiation; (7) although the exact mechanism of teratogenesis is not understood, it was pointed out that fluorescent localization data and the experiments reported herein indicate a similarity between teratogenic antiserum and trypan blue; (8) the importance of yolk sac pathology during the period of differentiation is discussed as it pertains to normal embryology, teratogenesis and the utilization of animals in drug testing programs for the evaluation of teratogenic effects.


Algae is very sensitive to outside factors.  Detergents are a leading pollutant of water sources.  The many ingredients of detergents can have either an antagonistic, additive, or synergistic effect on the toxicity of water.  It is now common for environmentally friendly detergents to be phosphate free although not much is known about their effect on aquatic environments.  We studied the effects of one detergent containing phosphate, and two phosphate free, plant based detergents on the dissolved oxygen of algae.  It was found that USDA certified environmentally friendly products do decrease eutrophication of algae.  An environmentally friendly detergent that was not USDA certified, had the same effects as a phosphate containing, non-environmentally friendly detergent.


Report an the diet and health survey of middle class families in Bombay City by the Indian Statistical Institute (Bombay Branch), 1949, Price Re. 1 I . This is the result of a survey, conducted by the Bombay Branch of the Indian Statistical Institute to investigate into the health and diet standards of m1ddle class populCJtion in Bombay. The infol·mation collected will be useful as a scientific assessment of economic position of middle class people in a part of the Bombay City. The report is comprehensive in matters of information and it must be noted that in the presentation ot the report Mr. K. C. Cheriyan and Dr. N. S . R. Sastry have tried to keep up to the standard recommended in the recent publication, The preparation of sampling survey reports. of the Sampling Sub-Commission of the Statist•cal Commission of the UNO. Thereare some minor defects in the presentation which must have ~scaped the notice of the authors . There is an omission in the numbering of tables and the references to these in the text are inconvenient for the reader. Except for such minor defects the report is an able presentation of information on diet and health of the middle classe pepoles.


There are many subclasses of analytic and univalent func- tions. The object of this paper is to introduce new classes and we have attempted to obtain coecient estimate, distortion theorem, radius of star- likeness, convexity and closure theorem for the classes S ⁄ (fi,fl,»,∞) and K ⁄ (fi,fl,»,∞) on the lines of (1) and (2). Results obtained by (1) and (2) which are particular cases of the parameters involved here, are also pointed out.


This paper concerns a concept of frequency-based quadratic dissipativity and its reduction to an equivalent H/sub /spl infin// (or /spl mu/) condition. The paper is motivated by the observation that a strictly proper system cannot be strictly passive; hence, results on the synthesis of positive real systems using the Cayley transform directly cannot be applied in most physical situations.


The structures of the lead sulphide and lead selenide based photoresistors are examined. The simulation allowed us to explain the experimentally observed differences in the photoconductivity relaxation time between two different types of photoresistors.


Abstract : Following the dissolution of the Soviet Union in 1991, black markets for nuclear material rapidly expanded and proliferation by both state and non-state actors soared. The Department of Defense began a lengthy process of creating mechanisms to address the proliferation through what ultimately became a strategic comprised of three pillars: nonproliferation, counterproliferation, and consequence management. The Department of Defense ultimately achieved unity of command by enforcing organizational changes within the department, establishing a new functional combatant command with a sub-unified command that maintains responsibility for integrating and synchronizing plans and operations to counter proliferation, and by establishing contingency plans to address known proliferation events. By studying strategic documents, operations plans, unified command plans, and organizational histories, the author determined that key to counterproliferation has been unity of command. While unity of command was not immediate, the department did achieve unity of effort early, which mitigated serious consequences.


The study of sliding movements of actin filaments on a surface-fixed myosin in an in vitro motility assay presents a useful method employed to understand the mechanisms of muscle contraction. In order to gain insight into this study, we here propose a novel method to create "spatiotemporal color patterns" of a moving thin filament. First, we verified the method by using artificial patterns generated by computer simulations. Then we gleaned coordinate data of actin filaments from video images by applying digital processing, and expressed the results with the patterns. With this method, the existence of fluctuations in the sliding velocity and/or locus were clearly visualized. As a result, we could also develop a new effective method to accurately determine the sliding velocity of the transforming filaments. In addition, we will discuss the complementarity between the velocity and the length of the filament as they can not be determined simultaneously.


In the ideological system of Michel Foucault,school is not a educational place that can promote development and growth,but a important disciplinary field full of power technologies. Therefore,the allocation of school time isn't the demand of education,but the operation of power. The school time is being segmented,inserted,synchronized,repelled,stretched and internalized so as to operate the discipline. And this makes the students' bodies show the states of fragmentation,indifference and mechanization.


A phenomenological quantum theory of the normal skin effect in semimetals in a magnetic field which is valid for an arbitrary relation between the wave frequency w and the electron-hole recombination time T is developed. A feature of the theory is that the appearance of nonequilibrium carriers in the wave, including quantum effects due to the dependence of carrier concentration in the semimetal on magnetic induction f/J is consistently taken into account. It is assumed that w1 is large compared to the intraband relaxation times and hence the kinetic analysis is combined with a thermodynamic description of the carriers in each of the bands. Consequently the impedance and wave attenuation factor can be related to the dependence of carrier concentration and magnetic susceptibility Jl on .9J under thermodynamic equilibrium conditions. In the quasiclassicallimit in a certain frequency range, the skin-effect pattern for a single oscillation of Jl (.srJ) may vary from that characteristic of a monopolar metal to that characteristic of a compensated metal (with a greatly increased skin depth). Some features of wave propagation under purely quantum conditions are also investigated. It is shown, in particular, that for a certain relation between the parameters, a wave with a purely longitudinal electrical field and transverse magnetic field, but with vanishing magnetic induction, may arise.


Meetings comprise a vital part of participation in social activities. For a deaf or hard of hearing person who does not understand spoken language, following meetings can become confusing if there are too many simultaneous sources of information. When the person focuses on one source of information, she misses information from another source; for example, while looking at a presenter's slides, the person misses information from the signing interpreter. The features of Facetop Tablet were iteratively designed according to feedback from members of the Deaf community. Through this feedback, we have refined and completed the implementation and it is ready for evaluation through user studies. We are ready to recruit participants whom we could reach through demonstrations.


A 57-year-old man with no prior medical illness complained of fever and cough for 6 days, followed by breathlessness 3 days later. He had close contact with his daughter-in-law, and was diagnosed with COVID-19 2 days prior. On arrival, he was febrile (body temperature = 38.5°C), not tachypneic, and had oxygen saturation of 99% on room air measured by pulse oximetry. Chest radiography showed ground-glass opacities in the bilateral lower zones. COVID-19 was confirmed by the detection of SARS-CoV-2 in nasopharyngeal and oropharyngeal swab samples using RT-PCR. In the ward, his clinical condition deteriorated with worsening of inflammatory markers and progressive hypoxemia that required oxygen supplementation via face mask on the third day of hospitalization and mechanical ventilation 3 days later. He responded well to intravenous dexamethasone and was extubated after 3 days. Computed tomography of the thorax revealed organizing pneumonia and pneumomediastinum (Figure 1). He still complained of cough but denied chest pain or worsening dyspnea. He received a tapering dose of oral prednisolone and underwent pulmonary rehabilitation in the ward. Pneumomediastinum was managed conservatively owing to general improvement. Oxygen support was weaned off, and he was discharged.


The author has previously reported the experimental study on the use of dried Natto powder and dried salt-reduced Miso for feeding white rats, in which better results were obtained in growth of weight and in nitrogen and amino-acid metabolism than by feeding with autoclaved soybean powder, and the conclusion was that Natto powder can be used to feed infants. In this study, Natto powder milk was prepared with Natto powder as protein source, and human infants were actually fed with it. 1. Materials The Natto powder used in the study was prepared at the laboratory of Prof. Sakurai of Agricultural Department, Tokyo University. Its composition was as shown in Tab. 1. Its protein content was 40.62 % the protein coefficient of 5.71 being applied.


Venezuelan artist Rafaela Baroni (1935–) is the subject of Sergio Chejfec's Baroni: A Journey, yet its psychogeographic art tour conflates sculptures and embalmed bodies, past and present, landscape and paper, not to mention the countless streets and plazas in Venezuela named for Simón Bolívar. As the narrator says, his is a confusion "so ingrained that it was a cadence, or an inclination, assumed as natural, much like a chronic pain":


Football and competition are synonymous. Scan the terrain and conflict is everywhere, from Mourinho v Conte, Messi v Ronaldo, Germany v England, Everton v Liverpool, fans in the pub, fellas in their Sunday league teams or a random group of kids in the park with an hour to spare and ball to share – we – the football mass love competition – it's an embedded part of game. However, the (radical) commercial actors embedded in the game are also infatuated with competition, creating aggressive commercial competitiveness between players, clubs and leagues on a local and global scale.


Subject of research: static characteristics of nodes of 6 kV power supply systems with asynchronous load.
Purpose of research: experimental determination of static characteristics by active and reactive power, calculation of the reserve coefficient by static stability of a node with asynchronous load.
Object of research: power supply systems with a complex load, which includes asynchronous motors.
Main results of research: the results of an active experiment to determine the static characteristics of the load node are presented. The measurements were carried out using devices that record the quality of electricity. Voltage regulation was carried out by the RPN device, the current transformers on the input switch were selected as the connection point of the device. Static characteristics of active and reactive power were constructed using interpolation and extrapolation tools. The critical voltage of the load node is determined. The coefficient of static stability margin is determined.


Over the course of the past hundred years, tourism has become one of the most important sectors of the economy of the Caribbean basin. This industry has had a variety of effects (which we might call, following some economists, "multiplier effects") on other sectors of culture that, some important contributions notwithstanding (Pattullo 1996; Taylor 1993; Schwartz 1997), have remained understudied. During the last ten years in Puerto Rico, the government has turned once again to tourism to rescue its failing economic model, making tourism the "punta de lanza de la economía," as former Governor Pedro Roselló put it. This, of course, follows a global pattern in which tourism has become the solution to economic problems not only in the less developed countries, but also in urban and rural areas of the United States and Europe. In Puerto Rico, this emergence is part of a cyclical, continual revival in which tourism appears not only as the island's major economic asset during troubled times, but also as a referential system that grounds Puerto Rican cultural nationalism.1 The purpose of this essay is to explore how tourism was related to the culturalnationalist discourse that emerged during the 1930s. By focusing on a series of articles that appeared in the magazine Puerto Rico Ilustrado during that


After the world war II, Germany's emphasis on the development of science and technology is unprecedented, which not only promotes the development of science and technology, but also gives itself an advantage in the international competition. In the face of the global financial crisis, Germany takes lots of measures under the government's intervention, such as strongly supporting the cooperation between departments, fields and countries, vigorously developing green energy and strengthening the support to the emerging technology areas by firmly grasping the development trends of the international science and technology, which all contribute to ensuring itself a greater leap in the new era.


Human African Trypanosomiasis (HAT) or "Sleeping Sickness" is a potentially fatal but curable, neglected tropical diseaseseen in sub-Saharan Africa. HAT was nearly eliminated in the 1960s, but has re-emerged in epidemic proportions over the pasttwo decades. We report a case of HAT in order to highlight a possible re-emergence of this rare tropical disease, as well as itstreatment challenges. A.C is a 14-year-old male patient who presented with clinical features suggestive of the chronic form ofthe disease. Despite the prescription of IV Eflornithine, the drug could not be procured. Unfortunately, the patient was lost tofollow-up. This treatment gap underscores the need for emphasis on preventive measures such as eradication of tsetse flies, andreduction of the spread of parasites especially in resource-limited settings of sub-Saharan Africa.


This poster presents the R4Platform which provides an integrated set of tools and services that can be used as an enabler for continuous performance auditing in the built environment. The objective is to provide a modular set of components that when composed can provide an end-to-end auditing system for building managers, ESCOs and energy providers. The poster will present the platform architecture and its application in a real world environment, this will include a visual demonstration of the platform.


A microfluidic biochip integrated with highly sensitive fiber-optic glucose biosensor is presented. With the layer-by-layer self-assembly technology, poly (ethylenimine) (PEI), poly (acrylic acid) (PAA) and glucose oxidase (GOx) multilayers were deposited on the surface of a long-period fiber grating for sensing of glucose. Experimental results reveal that the biochip can achieve ultra-low detection limit (1 nM) and is very promising for diabetes mellitus detection.


Laser‐induced fluorescence (LIF) spectra of the A–X system of the LiH isotopes, excited by the UV lines of an argon and a krypton ion laser, were observed and analyzed. Three long LIF series of different LiH isotopes were taken with a 3.4 m high resolution spectrograph. The results were combined with previous experimental data to study the breakdown of the Born–Oppenheimer approximation in the X 1Σ+ electronic ground state of the isotopic LiH molecules. Using a quantum mechanical variational method, potential energy curves of the four LiH isotopes were extended almost up to the dissociation limits.


The method of manufacturing a heat exchanger is disclosed. The heat exchanger includes a plurality of pin members (10) having a plurality of pins (11) projecting and arranged in parallel from the flat base 12 so as to form the respective side end portions in the width direction of the slit portion base 12, and the pin member are arranged so that each of the base abut one another in the frame. Specifically, the manufacturing method is a long pin member (10L) for the extrusion molding operation for extrusion, the long fin member (11L) of the pin for cutting the long-fin member (10L) of the extruded immediately to cut at a predetermined width and cutting, the slit portion (12c) is included so that the long fin base cutting operation of cutting the long base portion (12L) of the cutting region (13X) formed on the fin cutting operation form.


In order to solve the problems of a heat pump air conditioner for an electric
 bus under extreme conditions, such as the large compression ratio, the high
 discharge temperature, the reduced system performance, the frequent
 shutdown of the compressor due to the overheat protection, this paper
 proposes a vapor injection technology with an economizer, and carries out a
 theoretical analysis of the process to reveal the effect of the vapor
 injection technology on the performance of the air conditioner. The results
 show that at ultra-low temperature heating operating conditions, when the
 compressor speed increases from 2000 rpm to 5000 rpm, the heating capacity
 of the vapor injection system increases from 16.2% to 22.7%, and the heating
 performance coefficient increases from 2.8% to 14.2%.


One of the greatest challenges of the contemporary world is the refractory problem of deforestation, with its catastrophic consequences in terms of biodiversity loss, climate change, disruption of the hydrological cycle, and the loss of livelihood for forest communities. It impacts the daily life of hundreds of millions of people around the world. Yet, in several parts of the world, forest sectors – that are frequently responsible for water management issues, especially in mountainous regions – are consistently marginalized in public budget allocations as well as in private investment decision. Reasons cited for the marginalization of the forestry sector in government budget allocations are the lack of understanding by senior policy makers and planners of the broad range of benefits provided by forests to local communities and national and regional economies, and the fact that many governments have traditionally neglected these issues.


Hinton-Jones, M., Valentine, J. (2008). Variety and altitude effects on yield and other characters of SRC willow in Wales.  Pp. 67-73 in: Aspects of Applied Biology 90, Biomass and Energy Crops III, Booth, E., Green, M., Karp, A., Shield, I., Stock, D., Turley, D., (Eds). Proceedings of the AAB Biomass and Energy Crops III conference, Sand Hutton, UK, 10-12 December 2008. Sponsorship: ERDF, WAG, WDA


Evaluators tend to see the rank and file as suppliers of data and as an audience awaiting what is distilled from the data. The humanist evaluator is a teacher who turns the rank and file into investigators.


The absorption spectra of aqueous solutions of ferric chloride have been examined qualitatively by Jones and Anderson, and quantitatively by Ewan, but Ewan's measurements were confined to very dilute solutions. It was thought, therefore, that quantitative measurements might profitably be carried out on more concentrated solutions of ferric chloride and on solutions of other salts of iron.


Random disturbances arising from the roadway are among the causes of many mechanical defects leading to discomfort
and road users' fatigue. Traditional mechanics analysis, based on the deterministic approach, is unfeasible
when we take into account all the non-controllable effects to explain the physical phenomenon. In this present
work, we used the spectral theory to analyse the dynamic behavior of a vehicle in order to get the probabilistic
characteristics output knowing the input characteristics. To overcome the difficulties encountered in the matrix
elements calculation of the transfer functions, we developed a simple numerical procedure as presented in this
work.


poser and subsequently processed so as to achieve what the composer describes as 'things that orchestras shouldn't be able to do', is promising indeed, but I'm not entirely sure that the resulting music really fulfils that promise, often coagulating into a thick, generalised and only minimally articulated flux of sound, whose internal details are often difficult to resolve and from which the music seems to struggle to emerge. I've known and followed Mercer's work since first encountering it in 2002 when he was still a doctoral student in San Diego, and he struck me then as one of the most timbrally inventive composers I had encountered in a long time, particularly in terms of combining disparate acoustic materials into textures of startling complexity and originality, but here the proliferation seems to have led to somewhat diminishing returns and an overall form which remains imprecise and obscure. Nevertheless I'm always attracted by the kind of musical imagination that seems to be motivated by the question 'what if . . .?' and that is certainly the case here. The third piece, quarks, is an improvisatory collaboration between vocalist Charmaine Lee and electronics performer Sam Pluta, in which Lee's voice, swooping through a kaleidoscope of vocal expressions from clicks, stutters and sighs to whistles, kisses and sharp intakes of breath, is digitally dissected into its smallest components – hence the title, I would assume – and reassembled into whirls of sound-particles to which the voice responds, and so on. There's an exhilaration about the rapidity with which these two composer-performers weave around each other, and the precision with which their sounds interact, coalesce and explode apart, that left me wishing it had continued for a lot longer than just under nine minutes. Finally, Aaron Cassidy's I, for example (the title derives from a quotation from Dostoyevsky found in the New York Times in 2017) is described in the liner note as 'politically charged', for no reason I can discern, and as deriving from improvisations. The degree of transformation undergone in many parameters by the sound materials in this piece, and its persistent reliance on frequency-domain processing techniques, lends it a certain very 'digital' homogeneity, and its succession of more or less dense textures often seems arbitrary. While structural homogeneity is often a feature of Cassidy's instrumental music, here the microstructures beneath that homogeneous surface seem to be missing the definition and attraction that the instabilities built into his multilayered notations can produce in the hands and mouths of expert performers. This is not to say that improvisational means of producing musical materials necessarily lead to such arbitrariness, or that digital processing necessarily leads to such ironing-out of articulative detail – there is plenty of music produced in recent decades that proves quite the opposite – but that there are aspects of this music that seem underdeveloped and indeed lacking in the sense of purpose that a 'politically charged' music ought to have.


This paper addresses the feasibility of computerized record-keeping for low-budget volunteer organizations, and presents results of an experiment designed to determine a fast, reliable, and comfortable data entry technique for enabling non-computer-user to enter large amounts of manually recorded data into a computer file.


To improve cure rates for neuroblastoma (NB), it is important and necessary to evaluate therapy response. Our investigation focuses on using plasma cell free DNA (cfDNA) as a biomarker to determine tumor burden and minimal residual disease (MRD) of NB patients during chemotherapy.


Filter paper splash procedure is a kind of measuring means to raindrop size. It is used widely and operated briefly and its cost is low. The article mainly introduces the influence of different heights to the stain diameter and the relationship between stain diameter and the raindrops. According to the experiment, the relation between the stain diameter and the raindrops is d=0.478D0.610.it is the research foundation of filter paper stain method. According to the data from Fangxian area using the method of filter paper splash procedure, we can conclude that the raindrop kinetic energy has a positive relationship with rainfall intensity. The research is useful for measuring the water and soil loss.Water and soil loss is one of the global environment problems. The most important factor which can cause water and soil loss is rainfall. The research on raindrop kinetic energy is important for the further analysis of water and soil loss. A classical approach for the research on raindrop kinetic energy is paper splash procedure. The relationship between stain diameter and raindrop diameter shall be calibrated in this approach. In general, influences from titrated water drop height and stain diameter are not considered in the calibration process. In this experiment, influences of rain drop height on stain diameter are researched in the stain calibration, settling basis for the research on local volume of water and soil loss.


The main objective of this article is an analysis of editorial practices and policies concerning peer review from 79 international scientific journals in Arts and Humanities and Social Sciences, based on statements found on these journals' own Web sites. The information sources used to identify and select each journal were the databases of Web of Science, in particular Arts & Humanities Citation Index and Social Sciences Citation Index. The analysis checked 30 parameters structured in a Data Collection Sheet (DCS), which were taken from the revised assessment criteria proposed by Delgado and others (2007). In general, these journals have a low average of reported informational parameters. Of all the journals that make up the Humanities' area, informational parameters about peer review editorial practices mentioned average 5.6 %. As for the 58 journals comprising the Social Sciences, their average for the cited parameters was 9.7 %. We conclude this study by providing a range of measures for their improvement and further alignment with the patterns of scholarly communication.


Starting from the structure of C26 fullerene and by using a series of map operations, a series of hyperstructures were obtained and investigated. A series of measures were performed in order to characterize the obtained hyperstructures and the estimations of the relationship between them were done. Images of two hyperstructures showing greatest informational entropy and lowest energy respectively between investigated ones, geometry optimized are given.


This paper describes a study of the current transients associated with glove or bare-skin contact experienced by linemen working from an insulated aerial device. The duration of the electrical shock, the peak current and the current time integral are calculated in order to evaluate the shock severity.


Combined type of small cell lung carcinoma (SCLC) is a rare malignancy of the lung that is usually peripheral and diagnosed after resection. We report an unusual case of centrally located combined SCLC with squamous cell component that was diagnosed on endobronchial lung biopsy.


This paper introduces a procedure called traffic engineering for grids for enabling grid networks to self-adjust to resource availability. The proposal is based on monitoring the state of resources and on task migration. It involves several layers of the Internet architecture. Experiments executed in NS-2 are used to illustrate the efficacy of the procedure proposed.


Thank you very much for downloading roman villas a study in social structure. As you may know, people have search numerous times for their favorite novels like this roman villas a study in social structure, but end up in infectious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they are facing with some harmful virus inside their computer. roman villas a study in social structure is available in our book collection an online access to it is set as public so you can download it instantly. Our books collection saves in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Merely said, the roman villas a study in social structure is universally compatible with any devices to read.


This article proves the necessity of international economic integration between Zabaikalsky Krai and crossborder territories of China. The possibility of increasing regional integration between Zabaikalsky Krai and China is based on complementarity and interdependence of the economic potentials of both sides. At the same time, the existing national differences at the level of development of the adjacent socioeconomic systems need a common system of goals, balance of priorities in their achievement, which, in its turn, implies a coherent integration policy between two regions — Zabaikalsky Krai and Inner Mongolia Autonomous Region. However, the lack of unified theoretical and methodological basis for international regional integration restrains the formation of the existing policy. In the context of multiple and ambiguous scientific approaches to international system, it is proposed to consider the "theory of relationships", by Professor Qin Yatsin, as the scientific basis for international regional integration, which proves the need and possibility of harmonising relationships between participants of international exchanges. From the author's point of view, the practical implementation of the "theory of relations" is possible within the framework of the process approach, which implies the interaction of international integration participants in achieving overall results. The use of the process approach as a methodological basis for regional integration allows to balance the interests of the sides of integration and identify their priorities. The proposed paradigm of international relations is supplemented by the author's classification of the processes, the assessment of their impact on the results of integration. It is shown that the interaction of the processes is sufficiently stable, predictable, manageable, hence the use of the process approach in the development of international regional integration


In modern cities, a busy traffic is an acute problem. Therefore, road monitoring should become an essential feature of smart cities. The possible approach to car traffic control is the usage of neural networks. In this article, we consider the usability of this approach for the detection and classification of city traffic. The developed application is based on the convolutional neural network of the YOLOv3 system. With the testing data set of 750 images, the trained neural network showed an accuracy of 76%.


Introduction A 4-hour curriculum was developed to provide residents with information about the concepts of patient satisfaction and experience. The course focuses on the competencies of professionalism and interpersonal and communication skills. It is designed to allow participants to reflect on current knowledge of the patient experience and service principles and to develop a greater appreciation of these concepts' utility and importance to everyday work. Methods Thirty-two residents in 2015 and nine incoming residents in 2016 participated in weekly hour-long sessions over 4 weeks. The curriculum also included an optional fifth component, in which patient satisfaction data were provided to the residents. Residents participated in pre- and postcurriculum survey assessments regarding their awareness of concepts involving patient experience. Results Preliminary results suggested that residents found the curriculum beneficial and that it helped to increase their understanding of the relevance of patient satisfaction and experience education to their practice. Quarterly feedback from patient surveys was provided to residents, identifying strengths and opportunities for improvement. Discussion Given the growing importance and utilization of patient satisfaction surveys, residents participated in this educational intervention to determine if a novel curriculum and proactive approach to resident understanding and utilization of satisfaction data could result in increased patient satisfaction with resident interactions. The study is ongoing and longitudinal, with initial results encouraging.


It is no longer common for historians simply to dismiss Thomas Müntzer (before 1490-1525), as did G.R.Elton, by describing him as an "unrestrained fanatic" and "dangerous lunatic."' Rather, in recent decades there has been a new appreciation of the depth and originality of his thought, of the crucial role he played in the emerging Reformation movement in Germany, and of his intervention on the side of the commoners in the German Peasants' War. It may be too early, however, to speak of a new consensus in the interpretation of this perennially controversial f igure-even of one along the very general lines proposed by James Stayer, who stressed that, "However many disagreements remain, Müntzer is now acknowledged as fully and truly theologian and revolutionary." Many recent studies of Thomas Müntzer clearly do accept this view, but among church historians and theologians there is a certain continuing reluctance to admit that a sixteenth century theologian could also be a sociopolitical revolutionary or that the modern European revolutionary tradition (at least as it can now be reconstructed) has its origins in the Christian theology of the Reformation.


Visiones de Hollywood: la novela espanola como reflejo del debate  cinematografico de principios de siglo XX addition, they included the cinema as a theme in their literary works. Some fundamental features of several novels of the first third of the 20th century are studied in this article, and they show the reflections and concerns that gave rise to this new art in the writers of the time. Through these texts, I shall explain some of the most important ideas that made debate over the cinema in those years, such as the falsity of the cinema, the mythomania created around the actors, the reflections on the public, the aesthetic possibilities of the new show and its comparison with the theatre. Almost all of them narrate the arrival in Hollywood of an aspiring actor and describe the environment of the metropolis of the cinema of the 1920s and 1930s. In some cases it is narrated from the perspective of the Vanguard novel and, in others, from the postulates of the pre-war social novel.


Background In 2003 Messageries Lyonnaises de Presse (MLP), a press distributor, filed a complaint with the French Competition Council (hereinafter "the Council") against Nouvelles Messageries de…


The purpose of this study was to analyze the content of elementary art textbooks(grade 3 to grade 6) in order to examine how the idea of the 7th Korean National Art Curriculum was actually realized and embodied in the content itself, and to suggest a guidance in developing art textbooks for the next Korean National Art Curriculum, which will be followed in the near future. The comparison was applied to 4-grade elementary art textbooks developed and approved by the government(Ministry of Education & Human Resources Development, MOE) and KICE(Korea Institute of Curriculum & Evaluation). The study included 1) the relation between the content of the 7th Korean National Art Curriculum and that of the elementary art textbooks, 2) the analysis of the selected content and content organization, and 3) the analysis of artworks by artists and elementary students represented in the elementary art textbooks. Since the 7th Korean National Art Curriculum was notified in 1997, elementary art textbooks for grade 4 to grade 6 were developed in 2001 and 2002. Textbooks for elementary school will have been used for 5 years after they are released during the 7th Korean National Curriculum is in effect. Especially in Korea, elementary textbooks are developed after experimental-stage textbooks developed in advance. And they are only one kind developed unlike middle and high school ones, which are developed by several different private publishing companies and chosen by the national authorization. A study on the content analysis of elementary art textbooks will be the basis for developing the next Korean Art Curriculum and art textbooks. Most of the problems found in this study were focused on the textbook authorization. To solve these and to improve the content of the art textbook, art textbooks should be developed not by the government but by free authors with different point of view.


This article argues that it is not the child's sleep disorder and the way it is put to bed–as subject to controversy in epidemiological studies–that encourage the incestual context or impinge on the child's autonomy. Rather it is the incestual context as Racamier understands it that fits into the phase of mutual narcissistic seduction in the mother-child intersubjective (or mothering parent-child) interaction and fosters the distortion of that relation due to the denial of an imaginary absence in the parent, a denial that contaminates the child. A fusional relationship of an incestuous nature is then perpetuated that transforms the bonds between the two partners into perverted narcissistic alliances that can lead to genitally or psychically expressed incest. Clinical studies show that this relational distortion is to be encountered both in the incestual mothering father-daughter context and in father-daughter incest.


Investigation is made clear on an identification method of a vortex from a circular cylinder by CAFV. The streamlines in coordinates for a cylinder is at rest or moves, the velocity vector, the streakline, the pathline, the vorticity, the isotherm, the timeline, and the isobar for the circular cylinder wake with the Reynolds number 44 and 70 are obtained and discussed.


Hot air drying suffers from two serious drawbacks. On the one hand it is very non-uniform even under well-controlled conditions, on the other, the rate falls of sharply towards the end of the drying period. Often the net result is a product which is unevenly dried at poor energy efficiecny. Radio-frequency power can remedy both of these shortcomings. The advantages of radio-frequency power in drying from the point of view of product quality and power costs are illustrated by reference to results obtained when drying paper and wool.


During walking in healthy adults, characteristic movement patterns between the upper and lower body relate directly to walking velocity. In persons who suffer a stroke, walking velocity decreases as motor deficits appear in both the arm and leg opposite the side of the stroke. Recent findings indicate that treadmill walking to a metronome beat impacts arm motion, however, the effect is dependent on the severity of motor deficits. The changes in arm motion lead to changes that are indicative of improvements in overall walking function. The purpose of this project is to determine the efficacy of over-ground gait training using an external auditory rhythm directed at arm movement versus leg movement on improving movement coordination, walking velocity, and daily physical activity in persons who have suffered a stroke.


We report the case of a patient presented to the emergency department because of a contusive trauma from a pressurized bottled drink cap. During the visit, the patient indicated that he had been hit in his left eye by a cork while he was opening a sparkling wine bottle. He underwent a total ophthalmology examination. He had an important reduction of visual acuity, corneal swelling, Descemet's folds, and hyphema. Therefore, we decided to perform ultrabiomicroscopy (UBM) of the anterior segment to study the endothelial damage and Descemet's membrane. UBM images confirmed the direct biomicroscopy, highlighting the damaged location.


This presentation is a historical review of foot deformity in the U.S. Army and the struggle to objectively determine when a specific foot type would be unable to meet the physical requirements of soldiering. This presentation begins with the Civil War, where attempts were made to adequately describe a pathologic foot structure, to the end of World War I, where orthopedic surgeons made significant headway in the assessment and treatment of foot deformities of the soldier. The influence of society and technology at the beginning of the 20th century led the hierarchy of the American Orthopaedic Association to persuade the U.S. Army to seriously consider foot deformities, from assessment to treatment, not only for the benefit of soldiers, but also for the new industrialized workers. This injury prevention approach focused not only on the examination of the "deformity," but also on treatment algorithms that were established at development battalions. In the 100 years since World War I, the lack of research using objective measures in both foot form and function to determine the existence of pathologic foot types has been significant.


Beryllium (Be), cobalt (Co), thallium (Tl) and vanadium (V) are candidates of 21 priority soil pollutants in Korea. The distribution of their concentration in soils from three contamination sources including industrial, roadside and mining areas was investigated. Concentrations of the metals were ev...


To the Editor: In the recent paper of Corston, Kendall and Marshall on middle cerebral artery stenosis published in the March-April 1984 STROKE, the authors proposed that the prognosis of this condition was not as benign as that previously reported by Hinton et al.' In fact, a critical review of the series of Corston et al. does reveal a surprisingly benign clinical course. Of the eleven patients in their series treated with aspirin, aspirin and dipyrimadole, or nothing at all, six suffered no new deficits during follow-up. There were three deaths, two due to cancer, and one from unknown causes, and there were only two strokes. 1 would have anticipated many more neurologic complications in this group. Because the paper of Hinton et al. suggests that Warfarin might be an effective treatment for middle cerebral artery stenosis, I was interested in the outcome of the patients in Corston, Kendall and Marshall's group who were treated with this medication. Only two patients in their series appear to have been treated with Warfarin throughout the entire duration of their follow-up. If my interpretation of their paper is correct, only a single patient, badly impaired with an initial stroke, went on to have two additional strokes on Warfarin therapy. Could the authors tell us if their patient's Warfarin therapy was managed appropriately and if the strokes were suffered in the hemisphere ipsilateral to the stenosis. It was also interesting to note that of the four patients dying because of an infarct on the side of the middle cerebral stenosis, only one of these patients appears to have been on Warfarin at the time of the fatal stroke. R. Michael Scott, M.D., F.A.C.S. Department of Neurosurgery Tufts-New England Medical Center Boston, Massachusetts