In the expansive Rio Hotel and Casino in Las Vegas, I stood in line for around an hour and a half to pay for my badge for admittance into DEF CON 21, one of the largest hacker conventions in the world. The wad of cash in my hand felt heavier than it should have as I approached the badge vendor. DEF CON is an extravagant affair and attendees pay for it (though, from my own readings, the conference administrators work to keep the costs reduced). The line slowly trickled down the ramp into the hotel convention area where the badge booths were arranged. As I laid eyes on the convention, my jaw dropped. It was packed. Attendees were already moving hurriedly throughout the place, engaged in energetic conversations. Black tshirts— a kind of hacker uniform— were everywhere. Las Vegasand gamblingthemed décor lined the walls and floors. Already, I could see a line forming at the DEF CON merchandise booth. Miles, a hacker I had gotten to know throughout my research, mentioned that if I wanted some of the "swag" or "loot" (the conference merchandise), I should go ahead and get in line, a potential threeto fourhour wait. Seemingly, everyone wanted to purchase merchandise to provide some evidence they were in attendance. Wait too long and the loot runs out. After winding through the serpentine line of conference attendees waiting for admittance, I approached the badge vendors and (dearly) departed with almost $200. Stepping into the convention area, I felt that loss in the pit of my stomach. The con was huge and already bustling even though the badge line still wrapped around the interior of the enormous Rio hotel. I shuffled to the merchandise booth and scanned the prices. Merchandise was not extraordinarily pricey, but certainly not bargainbin cheap either. I peered into my wallet to inspect my cash reserves— not wanting to spend too much. As a graduate student, finances were tight and I had to pay for this entire trip out of pocket. But I wanted a shirt; evidence of attendance.


According to structural type of a building, construction load can be different because construction method and collateral condition corresponding to each structural type is different. Generally, construction load of design code is based on the research result on construction of flat plate building structures. Therefore, this design code for construction load may be inappropriate for construction of wall type building structures. In this paper, through field instrumentation on a wall type building structure, construction load was investigated and the behavior under construction was analyzed. According to the result of field instrumentation, construction load of the wall type building structure was lower than specified load by design code. However, unexpected additional load because of temperature changes and storage of steel bars occurred and it can be larger than specified construction load by design code. Therefore, this unexpected additional load should be considered reasonably to assure safety of construction and restrict cracks on the slab under construction.


Compressed Air Energy Storage (CAES) technology and electricity generation by this system are described in this paper. General performances and possible system efficiency definitions of those kinds of systems are indicated. Hybrid systems which consist of CAES and other Renewable Technologies—RT—(e.g. wind turbines) are presented. A possible location for CAES–RT in Poland is indicated. A dynamic mathematical model of CAES is presented; using this model the results for compressing and expanding operating modes are obtained.


Although Descemet's membrane endothelial keratoplasty represents the ideal of pure anatomic replacement surgery, results of a laboratory study indicate the procedure is still in an early stage of development.


In accordance with the practice of a hydropower station with high pressure, finite element method is used to analyze the stress and deformation of an underground steel bifurcation with gap existing between bifurcatio n and surrounding rock, in which the rock is considered to evoke elastic reactions to the bifurcation. The FEM analysis result of underground bifurcation indicates that rock has a great effect on bifurcation stress and can therefore reduce the thickness of the bifurcation.


A study of the effect of adding coarse and fine slate waste mass product to hot mix asphalt compound tested on 28 kilometers paved of the Brazilian BR-040 which carries about 5 thousand vehicles a day. The accumulation of this slate waste has become an environmental problem due to the lack of disposal facilities. In addition, the exploitation of virgin quarries of other suitable materials impacts on the environment. In spite of the unsuitability of the lamellar form (flat and elongated - 30%) of the aggregate produced by recycling this waste, and the unwillingness of some highway engineers, a low Los Angeles abrasion value product was attained to meet the ecological and technical requirements. This is also a matter of international concern, particularly in the United Kingdom. Although recent, the experience was based on observing a hot mix compound applied about 40 years ago with the material obtained directly from the matrix rock, that is, not from slate waste. For the covering abstract see ITRD E157233


One of the signal developments in contemporary criticism over the past several years has been the ascendancy of the colonial paradigm. In conjunction with this new turn, Frantz Fanon has now been reinstated as a global theorist, and not simply by those engaged in Third World or subaltern studies. In a recent collection centered on British romanticism, Jerome McGann opens a discussion of William Blake and Ezra Pound with an extended invocation of Fanon. Donald Pease has used Fanon to open an attack on Stephen Greenblatt's reading of the Henriad and the interdisciplinary practices of the new historicism. And Fanon, and published interpretations of Fanon, have become regularly cited in the rereadings of the Renaissance that have emerged from places like Sussex, Essex, and


In last number I pointed out where, in constructing a house, the water-closet ought to be placed with a view to its perfect ventilation, and shall now consider the various ways by which the sewage is at present conveyed through our houses, till it enters the main drain?a matter which has not received the attention it deserves from architects and builders, or, indeed, the public at large. Sufficient vigilance does not seem to be exercised over the parties entrusted with the laying of these internal fittings of houses, and as a result their imperfections are a continual source


The invention discloses a hydraulic cylinder structure for a drill pump, which comprises a plurality of suction hydraulic cylinders and a plurality of discharge hydraulic cylinders. Each suction hydraulic cylinder is communicated with the corresponding discharge hydraulic cylinder, the suction hydraulic cylinders and the discharge hydraulic cylinders are of an integral structure which is integrally formed, and the suction hydraulic cylinders and the discharge hydraulic cylinders form an integral hydraulic cylinder. The hydraulic cylinder structure for the drill pump reduces use of raw materials, lowers production cost, reduces processing faces, improves processing efficiency, and saves processing time.


(1) Johann Heinrich von Thünen Institute, Institute of Climate-Smart Agriculture, Braunschweig, Germany (firstname.lastname@example.com), (2) Institute for Landscape Biogeochemistry, Leibniz Centre for Agricultural Landscape Research, Müncheberg, Germany, (3) Institute of Agricultural and Nutritional Science, Martin-Luther-University Halle-Wittenberg, Germany, (4) Institute of Crop Science, University of Hohenheim, Germany, (5) Department for Crop Sciences, University of Göttingen, Germany, (6) Institute of Crop Science and Plant Breeding, Kiel University, Germany, (7) Department of Technology Assessment and Substance Cycles, Leibniz Institute for Agricultural Engineering Potsdam-Bornim, Germany, (8) Johann Heinrich von Thünen Institute, Institute of Agricultural Technology, Braunschweig, Germany


Histochemical studies of the lipids of the eye lenses by traditional lipid staining methods yield rather poor results: the majority of the lipids of the lenses are bound to proteins. On the other hand, the traditional fat dyes (oilred, Sudan black, Sudan 111) detect mainly free lipids. The organic solvents of these dyes are not indifferent to the lense lipids either. The lense lipids were examined with microscopic method based upon luminescence. The microscopic field was illuminated by incident light of a HBO mercury vapour lamp (Zeiss), through BG 4/3 filter. Intact human lenses of different ages, furthermore those of subjects suffering from atherosclerosis or diabetes, as well as human cataractous lenses were examined. Among the cataractous lenses there were congenital, traumatic and senile cataracts. The materials were fixed for 48 hours in 4 per cent solution of formaldehyde containing 1 per cent calcium chloride. After washing for 4 hours with tapwater 6 to 10 micron thick sections were cut with a freezing microtome. Staining: a.) with 0,1 per cent aqueous solution of phosphine (C19H10NZ02) for 10 minutes. Rinsing in dist. water. b.) With a 1 per cent aqueous solution of riboflavin (Chinoin, Budapest) for 20 minutes. Rinsing in dist. water. c.) With a 0,5 per cent aqueous solution of oxytetracyclinhydrochloride (Chinoin, Budapest) for 20 minutes. Rinsing in dist. water. d.) With a 0,5 per cent borate buffered solution (Mc William et al. 1959) of chlortetracyclinhydrochloride (Lederle). Rinsing in dist. water. e.) With an aqueous solution of coffeine benzpyrene (Berg, 1951) for 20


We present an extensive study about the formation of Ge nanocrystals by using two-step process deposition by a commercially UHVCVD system. We also investigate the growth duration effect on micro-Raman characterization in SiO2 matrix containing Ge-NCs. FTIR spectroscopy is employed to monitor the amount of various chemical bonds in SiO2 matrix embedded with Ge-NCs under various annealing temperatures. The C-V curves show the hysteresis indicating the charge storage. Furthermore, high temperature annealing effects are also presented and going to be discussed


Methylglyoxal (MGO), a byproduct of sugar and lipid metabolic processes, is a major glycating agent. This metabolite reacts with basic residues of proteins and promotes the formation of advanced glycation end products (AGEs). Although MGO and AGEs are widely discussed in the context of diabetes, until recently, MGO was thought to result from insufficient blood sugar control. A new report reveals that plasma MGO, and not blood sugar, distinguishes diabetic patients with no pain from those with pain. This ability brings to MGO a new applicability to disease diagnosis. Diseases with normal sugar conditions, such as hypertension, sepsis, and renal disease, are increasingly recognized as MGO-related. We review the role of MGO in drug-induced nephropathy, induction of hypertension by oral administration, and as a biomarker of sepsis. We also discuss the measurement of MGO and its stable metabolite d-lactate. The metabolism and pathogenic mechanisms of MGO need investigation in diverse disease models. Whether MGO can be considered as an individual pathological factor will be an interesting topic.


In industry non-contacting measurement systems are becoming more and more a necessity. Among non-contacting techniques, optical method enjoys the virtues of being whole-field and non-contaminating and is getting more and more acceptance by industries for characterization of microsystems. In this paper, a universal digital microscopic laser speckle interferometer, which is called "Microferoscope" in the paper, is presented. The system is designed for measuring microstructures and Micro-Electro-Mechanical Systems (MEMS) with rough surface. The method is based on laser speckle interferometry incorporating a long distance microscope (LDM), a CCD-Camera and a high precision phase shifting technique. In this paper, the theory and methodology of the universal digital laser Microferoscope are described. A special software program "OPTIS" is developed for automatic data acquisition and evaluation. The usefulness of the Microferoscope is demonstrated by examples of shape and displacement measurement for different samples.


Previous studies showed that great change in yield and physiological traits,desired traits and high yield could be obtained through controlling level of N.This paper summarized the physiological changes,including growth of plant,dry matter accumulation,photosynthetic efficiency,non-structural carbohydrates,quality of seeds and yield could be caused by level of N.


Autonomous Optical Navigation is essential for the proximity operations of space missions to asteroids that usually have irregular gravity fields. One core component of this navigation strategy is the Image Processing (IP) algorithm that extracts optical observables from images captured by the spacecraft's on-board camera. Among these observables, the centroid of the asteroid is important to determine the position between the spacecraft and the body, which is the focus of this research. However, the performance of standard IP algorithms is affected and constrained by the features of the images, such as the shape of the asteroid, the illumination conditions and the presence of additional bodies, therefore, the quality of the extracted optical observables is influenced. To address the latter two challenges, this paper develops a Convolutional Neural Networks (CNN)-based IP algorithm and applies it to the Early Characterization Phase (ECP) of the European Space Agency's HERA mission with the target body of binary asteroid Didymos. This algorithm is capable of estimating the centroid of the primary body successfully with high accuracy and without being affected by the presence of the secondary body or the illumination in the input images. In addition, it can also estimate the centroid of the secondary body when the two bodies are in the same image, which increases the robustness of the overall navigation strategy.


Balancing the intensity and duration of antiplatelet therapy according to thrombotic risk is a fundamental need in order to optimize therapy effectiveness and safety. Incorporation of new predictors in thrombotic risk stratification is therefore of a crucial importance for antiplatelet therapy net clinical benefit.

 The present analysis aimed to evaluate the relation of miR-126-3p and miR-223-3p, new markers of platelet activation, in order to facilitate prediction of recurrent thrombotic events after acute myocardial infarction (AMI).

 The analysis included 598 patients (age median 62 years, men 77.8%) randomized in the Prague-18 study (ticagrelor vs. prasugrel in AIM treated with primary PCI). During the study follow up, 40.6% of patients switched to clopidogrel. Determination of miR was evaluated 24 hours after admission; miR-126-3p and miR-223-3p were normalized by miR-423-3p and miR-150-5p. Quantitative determination of selected miRNAs was performed with a novel microRNA immunoassay method.
 Selected miRNAs were compared with key efficacy endpoints (cardiovascular death, nonfatal MI and stroke), stent thrombosis and all hemorrhagic events, and analysed using univariate and multivariate logistic regressions.

 Increased values of miR-223-3p were significantly related to the occurrence of combined ischemic endpoint within 30 days [OR (95% CI) 15.739 (2.066; 119.932) p=0.008] and within one year [3.175 (1.40; 7.186) p=0.006]. Decreased ratio of miR-126-3P/miR-223-3p was significantly related to the occurrence of combined ischemic endpoint within 30 days [0.137 (0.031; 0.609) p=0.009] and one year [0.372 (0.169; 0.819) p=0.014]. MiRNAs were identified as independent predictors even after adjustment for confounding clinical predictors (Study arm, Switch to Clopidogrel, Age, Men, BMI, Smoking, History of Hyperlipidemia, Hypertension, DM, MI, PCI, CABG, Chronic heart failure, Chronic renal failure, Peripheral arterial disease, LBBB, RBBB, TIMI <3 after PCI, Number of diseased vessels >1, Stem disease, Suboptimal of failure of PCI, Time to hospital). Adjusted ORs (95% CI) are 11.828 (1.472; 98.011), p=0.022 and 2.394 (1.021; 5.610), p=0.045 for increased value of miR-223-3p and the occurrence of combined ischemic endpoint within 30 days and one year respectively; 0.151 (0.030; 0.757), p=0.022 and 0.407 (0.179; 0.925), p=0.032 for decreased ratio of miR-126–3P/miR-223-3p and the occurrence of combined ischemic endpoint within 30 days and one year respectively. No association between miRNA and bleeding complications was identified.

 The miR-223-3p and miR-126-3p to miR-223-3p ratio are strong independent predictors of thrombotic ischemic events and can be used to stratify patients post AMI.


To study the seismic behavior of steel reinforced concrete cross-shaped columns, four specimens under constant axial load and cyclic lateral load were tested, and the effects of the axial compression ratio, the steel ratio and the loading direction on the failure modes, hysteretic behavior, deformation capacity and energy dissipation capacity of the specimens were analyzed. Based on the experimental results, a finite element analysis was carried out to simulate the behavior of the specimens, and the numerical results agreed well with the experimental results. The results show that steel reinforced concrete cross-shaped columns have favorable ductility, plastic deformation capacity and energy dissipation capacity. Compared with reinforced concrete cross-shaped columns, the steel reinforced concrete cross-shaped columns have higher bearing capacity and excellent seismic behavior, which can be used in high-rise buildings and the construction in high seismic fortification zone.


The resilient modulus (MR) of subgrade and unbound materials is significantly influenced by the changes in the soil physical state represented by its moisture content and dry density values. DARWin-ME requires the pavement designers to input the laboratory measured resilient modulus value at optimum moisture content for appropriate characterization of subgrade and unbound materials. The resilient modulus at optimum or near optimum moisture content represents the soil physical state at the time of subgrade construction. For new flexible pavement designs, the resilient modulus and the optimum moisture content values are relatively easier to obtain from historical construction records. However, for flexible pavement rehabilitation or reconstruction designs, identifying the as-constructed subgrade condition is not straight forward. The field subgrade modulus derived from backcalculation of deflection basin tests or DCP tests that reflect the "in situ" conditions at the time of overlay or reconstruction cannot be directly used without appropriate adjustments. The pavement designs are often confronted with a question of what input value of subgrade resilient modulus would be appropriate for use in flexible pavement rehabilitation designs. This paper proposes a simple method to determine the resilient modulus input value from field measurements with appropriate adjustments. These adjustments help to establish a correspondence between the input MR value adjusted for as-constructed conditions with the "in situ" MR measured at the time of deflection testing while keeping the DARWin-ME simulated postcompaction profile of subgrade MR variations unchanged.


Spiking neural networks (SNNs) are inspired from biological brains and have demonstrated great energy efficiency on hardware computing platforms. However, it is a challenge to implement an online training algorithm on SNN hardware to adapt to the realistic cognitive applications. Besides, the accuracies of SNN adopted rate-based coding scheme are highly depend on the number of coding timesteps, resulting in the long data processing time and massive power consumption. In this brief, a multilayer online training SNN accelerator based on spike-timing-dependent plasticity based back-propagation (BP-STDP) algorithm is carried out. To speed up the spike processing, a weighted neuron model is proposed according to the characteristics of BP-STDP training algorithm. In addition, the training module can reuse the integrate and fire arithmetic unit circuits in hidden layer neuron module, which can significantly reduce the hardware overheads. The proposed accelerator is verified on the Xilinx Virtex-7 FPGA under 100Mhz clock frequency for the application of handwritten digit recognition. The proposed accelerator achieves a 95.3% recognition accuracy rate while consuming 0.27 ms for recognizing one image, and 1.22 ms for training one image. Compared with the software implementation, the proposed accelerator demonstrates $41.87\times $ training speedup and $56.96\times $ recognizing speedup.


This thesis analyses the challenge by massive culture transmission to moral education of school from the angle of effect that massive culture transmission has on young students'mentality of moral values and moral concept. It points out that this challenge actually poses a historic requirement for moral modernization. Moral modernization means not only modern ways of education,but more important is modernization of value system. The mass media should undoubtedly take up the responsibility for this matter.


Clinical and experimental studies on the insulin-like activity and glucagon-like activity of blood were carried out from the view point of metabolic and neurogenic controls of the endocrine activity of pancratic islets. Insulin-like activity of blood was determined by Shimazu's rat diaphragm method and glucogonlike activity by Shinko's liver slice method. As the metabolic factors, the following three hexose, i.e., glucose, levulose and galoctose were employed by means of intravenous infusion and by oral administration. In clinical investigations, normal and diabetic subjects were examined with simultaneous follow-up of blood sugar level. In animal experiments, both normal and alloxan dogs of 7-10kg. body weight were used. Blood was drawn from V. pancreaticoduodenalis up., A. femoralis and V. femoralis and blood sugar level was determined by Hagedorn Jensen's method. The results are summarized as follows ; 1) In normal and diabetic subjects per oral administration of glucose induced an increase of insulinlike activity of blood. The one hour percent increase of this activity in normal subjects was more pronounced than that of diabetics. The diabetics who do not require insulin showed higher percent increase of insulin-like activity than the diabetics under insulin treatment. 2) Following intravenous infusion of glucose solution insulin-like activity of blood showed transient decrease and then turned to increase in normal subjects. The author has assumed, that this indicates a possible acceleration of insulin secretion by an initial consumption of blood insulin by infused glucose. In diabetics this transient decrease of insulin-like activity disappered with increasing severity of the disease, showing direct increase immediately following glucose infusion. The glucagon-like activity of blood of normal subjects showed a transient increase in 30 minutes after infusion of glucose solution but returned to preinjection level in 60minutes. In diabetics, however, with the increasing severity of the disease, this normal pattern of glucagon was lost. It decreased transiently at first and then increased upon glucose infusion. 3) Investigations on normal and alloxan dogs in case of intravenous infusion of glucose solution revealed almost the same pattern as normal subjects and diabetics as regard to the insulin-like activity of blood. The pattern of blood insulin-like activity showed slight modification following the insulin consumption in the blood. Glucagon-like activity of blood showed no particular change both in normal and alloxan dogs. In general, one can say that alloxan dogs tend to secrete glucagon rather slowly than normal dogs. After infusion of glucose solution an increase of A-V ratio was observed, resulting most plausibly from the increased glucose uptake in the peripheral tissue under the co-influence of insulin and glucagon.


These remarkable offer original and sensitive way of 'being in the world' which may still be as fruitful for theological education as more fashionable theoretical


The domestic private capital is characterized by relative concentration and profit pursuit. So with the development of state-owned economy, it is feasible for private capital to participate in the basic construction by means of BOT. Concrete measures may be taken from building external circumstances, giving play to the government's function and adopting flexible model.


The purpose of the present study was to compare the functions of observational learning among female basketball players in with different levels of self-efficacy in the first division clubs of Tehran. Therefore, 63 players voluntarily filled out the functions of observational learning (Cumming et al., 2005) and physical self-efficacy questionnaires (Ryckman et al., 1982). The players were assigned to upper and lower self-efficacy groups based on median. The data analyzed by MANOVA to compare the functions of observational learning in different levels of self-efficacy. According to the results, there were no differences between skill and performance functions in upper and lower self-efficacy groups, but there was significant difference between strategy function of 2 groups (p<0.017). Thus, it seems that skilled basketball players with upper self-efficacy use more observational-learning function. Research findings suggest that athletic trainers, sport psychologists and athletes at all levels and functions of observational learning can benefit as a powerful tool for the acquisition of motor skills and mental preparation of the athletes.


The influence of RE (RE = Yb, Sm) substitutions on the microstructure and superconducting properties of Y-Ba-Cu-O (YBCO) bulk superconductors has been studied for different RE concentrations and their combinations. Precursor powders YBa2Cu3O7-δ (Y-123), Y2O3 and CeO2 were enriched with different amounts of Yb2O3 and (or) Sm2O3 powders with the aim to increase critical current density, i.e., Jc, in self-field as well as in higher magnetic fields, by introducing additional pinning centers. YBCO bulk superconductors with RE2O3 addition were prepared by the optimized top-seeded melt-growth process in the form of single grains. Microstructure analysis revealed that RE2O3 addition leads to a higher amount of smaller Y2BaCuO5 (Y-211) particles, which is related to high critical current density (Jc ~ 7 × 104 A/cm2) of the samples with RE2O3 addition in low magnetic fields. In this paper, the effect of RE2O3 addition on Y-211 particle size, critical temperature Tc, and critical current density Jc is reported.


The traditional rehabilitation service and the early community rehabilitation service cannot meet the requirement of weak energy personage to live on their own or to return to the community.Most of the weak energy personage have to depend on their relatives or neighbors;they live in the community but they cannot get the technique of recovery of humanity care.The study of modern community recovery pattern is important in helping the weak energy personage to be out of difficulties,to develop and to return to the society.


On the basis of high-level molecular quantum mechanics, the zero-point-corrected energy for formation of the anti-anti conformer of carbonic acid from water and carbon dioxide is compensated by formation of the most stable dimer. Therefore, the zero-point-corrected energy for formation of the carbonic acid dimer from its constituents water and carbon dioxide is close to zero, and even slightly negative values seem to be possible. These results include new CCSD(T)/6-311++G(3df,3pd) calculations of the formation energy of carbonic acid from water and carbon dioxide, which gave an energy difference of between 8.2 and 9.2 kcal/mol which is lower than those reported before. Furthermore, the dimerization energy of carbonic acid and formic acid is reported up to the MP2/aug-cc-pVTZ level of theory, leading to a best estimate of −16.9 kcal/mol for the carbonic acid dimer relying on convergence considerations for the MP2/aug-cc-pVxZ level of theory that also clearly reveal the failure of counterpoise correction fo...


We studied the anxiolytic-like activity of alnespirone and buspirone, two 5-HT receptor agonists, in a modified 1A Geller–Seifter conflict model, and examined the role of 5-HT receptors by studying whether WAY-100635, a selective 1A antagonist at these receptors, blocked their effects. Administered s.c. 30 minutes before testing, 0.5 and 1 mgrkg ( ) alnespirone significantly increased punished responding, whereas lower doses 0.125 and 0.25 mgrkg had no effect. At ( ) 1 mgrkg, alnespirone significantly reduced the rates of unpunished responding. One dose of buspirone 1 mgrkg significantly increased punished responding and reduced unpunished responding. Lower doses were ineffective. Administered s.c. 40 minutes before testing, WAY-100635 had no effect on any parameter but completely antagonized the effects of ( ) ( ) alnespirone 1 mgrkg and buspirone 1 mgrkg on punished responding. The ability of buspirone to reduce unpunished responding was not antagonized by WAY-100635, probably reflecting a sedative effect of buspirone due to dopamine D receptor blockade. The results suggest that alnespirone and buspirone have anxiolytic-like activity in a conflict 2 procedure by stimulating 5-HT receptors, presumably at a presynaptic level. Like buspirone, alnespirone may have 1A useful effects in the treatment of anxiety disorders. Q 2000 Lippincott Williams & Wilkins.


In the last few years, quantum computing has evolved as the next big technological breakthrough. Many big companies are actively researching this area and have built open-source frameworks which can be used to develop solutions for problems that connect be solved by classical computers. One such problem is the solution of Navier-Stokes equations which takes exponential time for simulation but using quantum computers, they can be solved in polynomial time. But the current state of quantum computation does not enable everyone to test their implementation on a real quantum computer. In this situation, a simulator enables rapid prototype and testing techniques and algorithms for when the real quantum computer is ready. This paper focuses on simulating fluid flow algorithms using a quantum framework, such as Navier- Stokes equations, with the lattice Boltzmann method (LBM) used to numerically solve the relevant system of equations on both CPU and GPU to speed up the process. The quantum framework used in this paper is Qiskit, an open-source software development kit created by IBM that allows developers to create and test quantum algorithms. NVIDIA cuQuantum is an SDK of optimized libraries and tools for expediting quantum computing operations used in this paper to solve the fundamental problem of modeling large-size quantum circuits using the power of GPU


Abstract The problem considered is the computation reduction for general delete-d jackknife variance estimators. The delete-d jackknife estimator was proved consistent (Shao and Wu 1986), and in this article its mean squared error is shown to have order o(n –2), where n is the sample size. These properties are not shared by the traditional delete-1 jackknife in some situations. Use of the delete-d jackknife, however, requires ( n d ) recomputations of a point estimate θ, which increases rapidly as n and d increase. Using techniques from survey sampling, a shortcut can be taken with θ evaluated only m times, m ≪ ( n d ). The efficiency and consistency of the resulting jackknife-sampling (hybrid) variance estimators (JSVE's) are studied. If m is chosen so that n/m → 0, the increase in mean squared error by using the JSVE is relatively negligible. For the consistency of JSVE, m → ∞ is sufficient. Hence the JSVE with m < n can also be used to alleviate the computational burden for the delete-1 jackknife in th...


A design of hardware and software platform based on ARM(Advanced RISC Machines) meeting to the requisition of reliability and rapidity in fault line detection is presented.ARM processor LPC2214 with low power consumption makes the controlling core of this device.The software algorithm called integrated criterion of this device integrates several line detection methods to improve adaptability of the device.The advantages of ARM,excellent real time interrupt response and high calculating speed,make the synthetical intellective algorithm to be fast processed in time.The operation results show that this platform has good running stability,high adaptability and fault detection is fast and reliable,which may become an ideal earth-fault detection platform for its better performance-price ratio.


Over the last 40 years, the US has experienced a large increase in inequality. At the same time there has been a substantial increase in residential segregation by income and education. What is the link between inequality and residential and educational choice? We first document a strong correlation between inequality and residential segregation at the MSA level, especially in MSA with higher percentage of families with children. Then we develop a general equilibrium overlapping generations model where parents choose the neighborhood where they live with their children. The key ingredient of the model is that there is a spillover effect: children's future wage is expected to be higher if they live in richer neighborhoods. We model such a spillover effect as a black box that can be explained by different quality of public schools, peer effect, learning from neighbors' experience and so forth. This generates a general equilibrium effect through which the residential choice amplifies future inequality: the higher is inequality, the higher is residential segregation which, due to the spillover effect, generates higher inequality. Is this the end of the American dream? We then calibrate the model, using the elasticities found in Chetty and Hendren (2016) and quantify how much residential segregation has contributed to increase inequality. (We attach slides of a preliminary version of the paper, as the current version is still on progress).


This paper presents an attempt to analyse the growth of conflict in the context of globalization processes of the XXI century, in particular the clash of cultural and social identities. The development of digital technologies has provoked an increased array of information flows, which bring disorienting sentiments to society. This resulted in the spread of such social phenomena as "echo chamber" and gaslighting. Conflict of identities is a response to the collapse of a unified society. Purpose and objectives of the paper. The objective is to conduct a socio-philosophical analysis of identity as a conflict-causing phenomenon in the globalized digital age, based on the achievements of modern science and philosophy. Methodology of Research. The main research methods are structural-functional, philosophico-cultural and philosophico-anthropological. The principle "from abstract to concrete" and the principle of systemicity were applied to solve specific research tasks. Research results. On the one hand, modern globalization processes allow the interaction of previously distant or even mutually exclusive cultures, patterns of behaviour, or identities. On the other hand, there is a clash of previously separated and relatively closed cultural, civilizational groups, which becomes a catalyst in forming a completely new (or hybrid) identity and advocating existing identification values, where the alternative reality is perceived as a threat of losing the uniqueness or value of the heritage of generations. As a result, there is a conflict of identities at both the individual and social levels. Conclusion.The globalization processes of the XXI century are penetrating more and more actively into all spheres of social life: there is a clash of cultural and social identities, which provokes increasing conflict levels and grouping to preserve uniqueness in response to global trends, the establishment of new social norms and expansion of human rights. The world is in a state of formation, constant change, and the understanding of the described trends features and their mechanisms reveals their contradictory phenomena "echo chamber", gaslighting etc. "Otherness" has become an integral feature of today and in our opinion, the search for practices of mutual understanding is becoming another cultural challenge.


A review is made of existing literature concerned with the analytical investigation of the velocity and temperature distributions in the boundary layers of a heated (or cooled) flat plate. The plate is postulated infinitely thin and is parallel to a uniform fluid stream. The more recent solutions include the combined effects of frictional dissipation and variable fluid properties. Only the results pertaining to the transfer phenomena occurring at the plate surface are included, i.e., skin drag and over-all heat transfer; the individual temperature and velocity distributions leading to these results are omitted.


The lack of normalization of mental health as a conversational topic is becoming increasingly evident in certain cultures. The fact that students underutilize mental health services in schools can be attributed to the presence of various barriers that impede their willingness to seek help. Stigma surrounding mental health services continues to be the most prevalent barrier to help-seeking behaviour. Alternative barriers have emerged that are both personal and public in nature and can have a substantial impact on students' preferences to seek help in schools. A sequential explanatory study was carried out among 256 Muslim students in a school with a dual education system to explore both their self-stigma of seeking help (SSOSH) and mental health help-seeking attitude (MHSA). In addition, 12 students were interviewed in a focus group setting to explore further the phenomenon of help-seeking by students and understand the initial quantitative analysis. Preliminary findings indicated that the students' level of self-stigma was only moderate, but they had a favourable attitude towards counselling help. There was no significant difference in gender for both variables; however, the lower the self-stigma, the higher the mental help-seeking attitude for this current study, which is a common trend in the relationship between the two variables. The interview revealed that, apart from public stigma, the absence of a qualified counsellor, a lack of ethical principles of counselling, a confidentiality issue, and the emotional openness of the students were identified as other barriers to their help-seeking attitudes. This paper also discussed the recommendations made by students for addressing barriers to counselling and facilitating their counselling needs for the improvement of their mental and academic well-being. Additionally, this research offers the most recent data about mental health in the context of schools with a dual education system in Brunei Darussalam. It is hoped that it will serve as a guide for policymakers to consider the provision of mental health services that are more appealing to the students' mental and academic well-being.


The water in Cibeles Fountain flows in a closed circuit and is replaced every 6 months. After this period of time, an increase in bicarbonate, sulfate, calcium and magnesium contents is registered in the water, as well as a slight increase in its acidity. This acidity, favored by atmospheric pollution, is the main cause for the process of dissolution that marble used in the ornamental sections of the fountain undergoes. Calcite-based marble, from the Carrara quarries in Italy, of the cherubs suffers the most acute dissolution processes, while dolomite-based marble, used for the main sculpture body is less affected by these processes. Dissolved materials fall on certain sections of the sculpture and of the fountain forming dirt crusts and inlaid soiling.
In order to prevent decay of the fountain building materials, periodical control of water composition is necessary, with a view to stabilizing water pH level at around 7.8. It is likewise necessary to add chemicals that prevent bacteria and algae proliferation, thus improving water quality.


Neuronal activity and brain glucose metabolism are tightly coupled, where triggered neurotransmission leads to a higher demand for glucose. To better understand the regulation of neuronal activity and its relation to high-speed metabolism, development of analytical tools that can temporally resolve the transients of vesicular neurotransmitter release and fluctuations of metabolites such as glucose in the local vicinity of the activated neurons is needed. Here we present an amperometric biosensor design for rapid co-detection of glucose and the neurotransmitter dopamine. The sensor is based on the immobilization of an ultra-thin layer of glucose oxidase on to a gold-nanoparticle-covered carbon fiber microelectrode. Our electrode, by altering the potential applied at the sensor surface, allows for the high-speed recording of both glucose and dopamine. We demonstrate that, even though glucose is electrochemically detected indirectly through the enzymatic product and the electroactive dopamine is sensed directly, when exposing the sensor surface to a mixture of the two analytes, fluctuations in glucose and dopamine concentrations can be visu alized with similar speed and at a millisecond time scale. Hence, by minimizing the enzyme coating thickness at the sensor surface, dual detection of glucose and dopamine can be realized at the same sensor surface and at time scales necessary for monitoring fast metabolic alterations during neurotransmission.


During pregnancy, mothers generate di-galactosylated IgGs that cross the placenta more readily and provide the fetus and the newborn infant with antibodies optimized for NK cell–mediated antibody-dependent cellular cytotoxicity. During pregnancy, mothers generate di-galactosylated IgGs that cross the placenta more readily and provide the fetus and the newborn infant with antibodies optimized for NK cell–mediated antibody-dependent cellular cytotoxicity.


Nickel orthoborate Ni3(BO3)2
 nanoribbons were synthesized via a facile solid state reaction. The process is very simple and only two chemicals (H3BO3 and Ni(NO3)2) are used. It is the first time that well-defined 1D Ni3(BO3)2 nanoribbons can be obtained. The nanoribbons have widths in the range of 100–150 nm and length up to 20 μm. The antimicrobial studies show that the Ni3(BO3)2 nanoribbons have good antimicrobial activities towards Gram-negative bacteria and Gram-positive bacteria. In addition, we also explored the application of the Ni3(BO3)2 nanoribbons as electrochemical capacitors and found that the Ni3(BO3)2 nanoribbons have a large specific capacitance of 170 F g−1. The electric properties of single Ni3(BO3)2 nanoribbons were also investigated.


Experimental solubilities are reported for benzil (1,2-diphenylethanedione) dissolved in six binary mixtures containing methyl tert-butyl ether with hexane, heptane, octane, cyclohexane, methylcyclohexane and 2,2,4-trimethylpentane at 25 °C. Results of these measurements are used to test two mathematical representations based upon the combined nearly ideal binary solvent (NIBS)/Redlich−Kister equation and modified Wilson model. For the six systems studied, the combined NIBS/Redlich−Kister equation was found to provide the more accurate mathematical representation of the experimental data, with an overall average absolute deviation between measured and calculated values being on the order of 0.3%. Slightly larger deviations were noted in the case of the modified Wilson equation.


Lockdowns measures including closure of educational institutions due to COVID-19 may affect youth's activity patterns, psychological stress and obesity status. This is the first kind of study in India on the basis of a large number of teenage subjects from the COVID-19 Impact on Lifestyle Changes. Through an online questionnaire, 144 participants from high schools, aged 10-19 years, voluntarily reported their lifestyles and weight, basal metabolic rate (BMI) status in between 19th July to 12th August 2020 (before and after lockdown). Our data suggest that teenagers having prevalence of significant weight (49.6±15.5 to 52.1±15.2 Kgs p <0.001) and BMI (21.0± 1.2 to 22.7±.1.7 p<0.01) gain. Data further showed that this weight gain was for 71.1 % teenagers and BMI 67.2% subjects. Also, significant decreases were seen in the frequency of engaging in active physical activity, and leisure-time walking, while significant increases were observed in the average sedentary time during weekdays and weekends. Our findings would serve as important evidence for making strategies to counteract or reverse the lockdown effects on youths' obesity. OBESITY, EATING BEHAVIOR AND PHYSICAL ACTIVITY DURING COVID-19 LOCKDOWN: A STUDY OF INDIAN TEENAGERS Received on: 30.10.2021 Revised on: 12.11.2021 Accepted on: 18.11.2021


That Mao Zedong moves towards the Shaoshan period has been such character person,he has understood that in the field of the family,from father on one's body,to oppose the significance oppressing;From mother on one's body,he has obeyed the spirit feeling pity for the weak;In the field of society,among from current affair and progressive books,he has been produced saving the nation rescuing people mental consciousness.This three kinds character union are in having formed a quality must have by revolutionist together.


HeLa-cells labelled with 51Chromium start to release 51Cr into the medium 5-6 hours after infection with poliovirus. 51Cr-release is only observed when the viral genome is intact. Virus particles previously irradiated by UV do not cause chromium-release. Furthermore, protein synthesis must be allowed to proceed for 3-4 hours, p.i. for the effect to take place. Viral RNA synthesis is not required. Chromium release, release of viral particles and leakage of cellular proteins into the surrounding medium follow the same time course and have identical requirements. They are therefore considered to reflect a single phenomenon, a leakiness of the cell due to virus infection.


The disposal of ashes from power plants has caused health issues and reduce the air quality of the surrounding areas. The ashes have a potential to be used in construction of concrete mixture as partial replacement for cement. This research studies the potential fly ash and clay mixture (FAC) as a nuclear shielding material in concrete mixture. The raw materials and the testing were all done in Agensi Nuklear Malaysia. All concrete mixtures had a constant water/cement ratio of 0.266. The hardened concrete mixtures were tested for compressive strength. Scanning electron microscopy (SEM), energy dispersive X-ray (EDX) and small angle neutron microscopy (SANS) are used to characterize the properties of the mixtures. The results suggested that mixture of FAC concrete with 10% of clay addition showing good potential for nuclear shielding compared to other ratios.


Introduction to the Handbook Loads Design Philosophies Mechanical and Electrical Systems Vertical Transportation - Structural Aspects Welding-related Considerations in Building Design Structural Walls and Diaphragms - How They Function Structural Form Preliminary Design of Low-Rise Buildings Tall Buildings - Load Effects and Special Design Considerations Preliminary Design of High Rise Buildings Preliminary Design of Single-story Open-space Structures Preliminary Design of Shells and Folded Plates Preliminary Design of Space Trusses and Frames Preliminary Design of Lightweight Membrane Structures Including Air Supported and Structurally Supported Systems.


Abstract Eighty-one Chinese patients who became aphasic following a stroke are reported. Perisylvian aphasia syndromes were present in 18 (22·22%), borderzone aphasic syndromes in 19 (23·46%), global aphasia in 16 (19·76%), subcortical aphasia in 27 (33·3%) and anomic aphasia in only one (1·23%). Sixty-eight of 70 (97.1%) right-handed patients with aphasia had lesions located in the left hemisphere as defined by computed tomography. Nine of the 11 non-right-handed patients also had lesions located in the left hemisphere. The dominant hemisphere laterality of the majority of Chinese patients—whether right- or left-handed—was the left, and the classic aphasia patterns of Indo-European language speakers were readily demonstrated in Chinese-speaking subjects.


Both (+)-[18F]flubatine and its enantiomer (−)-[18F]flubatine are radioligands for the neuroimaging of α4β2 nicotinic acetylcholine receptors (nAChRs) by positron emission tomography (PET). In a clinical study in patients with early Alzheimer's disease, (+)-[18F]flubatine ((+)-[18F]1) was examined regarding its metabolic fate, in particular by identification of degradation products detected in plasma and urine. The investigations included an in vivo study of (+)-flubatine ((+)-1) in pigs and structural elucidation of formed metabolites by LC-MS/MS. Incubations of (+)-1 and (+)-[18F]1 with human liver microsomes were performed to generate in vitro metabolites, as well as radiometabolites, which enabled an assignment of their structures by comparison of LC-MS/MS and radio-HPLC data. Plasma and urine samples taken after administration of (+)-[18F]1 in humans were examined by radio-HPLC and, on the basis of results obtained in vitro and in vivo, formed radiometabolites were identified. In pigs, (+)-1 was monohydroxylated at different sites of the azabicyclic ring system of the molecule. Additionally, one intermediate metabolite underwent glucuronidation, as also demonstrated in vitro. In humans, a fraction of 95.9 ± 1.9% (n = 10) of unchanged tracer remained in plasma, 30 min after injection. However, despite the low metabolic degradation, both radiometabolites formed in humans could be characterized as (i) a product of C-hydroxylation at the azabicyclic ring system, and (ii) a glucuronide conjugate of the precedingly-formed N8-hydroxylated (+)-[18F]1.


A new kind of mobile emergency water supply facility of disc tube reverse osmosis(DTRO)is presented,in which technical characteristics,process and application range are introduced.The facts show that DTRO mobile emergency water supply facility has the characteristics of maneuverablility,stable,high reliability and so on.It is able to deal with various quality of water.Through water quality monitoring,the production water of this unit could meet the requirement of the standards for drinking water quality(GB 5749—2006).


ABSTRACT Limited attention has been devoted to the dimensionality of the low self-control scales commonly constructed in two nationally representative datasets routinely used to test self-control theory (SCT) – Add Health and NLSY79. We assess the measurement properties of the low self-control scales by comparing a series of exploratory and confirmatory models that are appropriate for the categorical nature of the observed items, including unidimensional, correlated factors, second-order factor, and bifactor models. Additionally, based on these results we explore the predictive validity of the respective scales on adolescents' delinquent behavior. The results indicate that the low self-control scales in these data have acceptable levels of internal consistency but do not represent unidimensional latent factors. Rather, scales are best represented by a second-order factor structure. When measured this way, our Add Health scale is associated with delinquency in a cross-sectional context and our NLSY79 scale predicts delinquency longitudinally. This study reveals that low self-control is best conceptualized as a multidimensional construct within these data. The results of this study provide guidance to researchers measuring low self-control in either dataset (or other data sources) and inform the larger SCT measurement literature.


Vertical movement of the larynx has been held responsible for two effects in speech production: a noticeable change in intraoral air pressure (P0) as a result of contraction or expansion of the oral cavity and perturbation of the fundamental frequency (F0) of neighboring vowels as a result of changes in the vertical tension of the vocal folds. Raising the larynx is supposed to elevate both P0 and F0, while lowering the larynx is supposed to reduce both parameters. Simultaneous measurements of larynx movement and P0 during the production of voiced and voiceless stops and ejectives by three speakers of Tigrinya showed that the larynx moves much too slowly to have any significant effect on P0. Computer simulation of the stops of this language confirmed this result. Larynx movement also could not be responsible for the perturbation of F0 in vowels following stops in Tigrinya since F0 was either not elevated or even depressed after stops which are produced with larynx raising, the voiceless stops, and ejective...


Coolmax fiber is used as the weft yarns of denim-like cotton/polyester fabric.The effects of alkali treating time on the morphology,denier,breaking strength,thermal performance,moisture permeability,quick-drying and dyeing performance of blended fabric are discussed,and are compared with those of polyester weft yarns.The results show that the fabric with alkali deweighting features increased absorbent property,deep color and good conductivity;the optimum alkali treating time is 35~60 min to ensure appropriate denier and breaking strength.Heat setting temperature of the fabric made of Coolmax fiber is 5~10 ℃ lower than that of conventional denim-like polyester fabric.


This article presents an algorithm for the detection of pedestrians in urban driving environments during the day. The main contribution is in the design of a new classifier to discriminate between the person and the background, under partial occlusion. To construct the classifier, the HOG (Histogram of Oriented Gradients) descriptor was used together with the SVM (Support Vector Machine) and IL (Logic Inference) algorithms.The input image has been divided into twelve regions, and for each of them the feature vector has been extracted and a classifier based on SVM has been built. With this design it is possible to capture the specific detail of each part of the human body, such as head, legs, arms and body. Subsequently, they have been joined in a final classifier using IL, in order to obtain an efficient algorithm to discriminate between partially occluded pedestrians and the background, in urban environments during the day. The experiments related to the classifier were developed onseveral public databases, in various degrees of partial occlusion; and the experiments linked to the detection were generated on the visual information obtained by the experimental platform ViiA, to validate the proposal under real driving conditions.


When young refugees who arrive in the European Union (EU) are categorized as "unaccompanied minors," an implicit assumption and ascription coincides with their categorization, namely that they are vulnerable. Being underage and being vulnerable are inextricably linked and often equated. Thus, vulnerability is understood as a bodily fact linked to a person's age, and discourse consequently overlooks how vulnerability is enacted in the EU's border regime. To demonstrate how vulnerability is produced and stabilized through entangled practices of human and nonhuman agencies, I examine vulnerability-making in the context of young refugees who were classified as "unaccompanied minors" in Malta. I pay specific attention to policies, documents, and spatiality and ask: How is vulnerability of young refugees in the EU's border regime produced and stabilized? And, how are nonhuman agencies implicated in these dynamics? The article, on one hand, makes an important empirical contribution to understanding the construction of vulnerability in respect to unaccompanied minors. The theoretical contribution of the article, on the other hand, lies in offering a new way of conceptualizing vulnerability in the border regime and within bordering practices in the EU by examining it through the epistemic lens of intra-action.


Much research has dealt with how social and organisational processes change when they take place in virtual spaces. This article considers innovation processes in which actors try to establish virtual worlds as platforms for professional communication. However, instead of focusing on internal communication processes in virtual worlds, the article seeks to question the dichotomy between physical and virtual worlds and to explore the importance of materiality in organising the virtual. Adopting a perspective inspired by actor-network theory, the article argues that physical places and objects do not only serve as context for innovation processes, but on the contrary are incorporated as strategic resources that actively help create the virtual worlds. The article is based on an empirical analysis of five Danish companies, and shows how companies make use of physical places and objects as strategic resources in the innovation process. Thus the article contributes to the literature on innovation in new media such as virtual worlds.


We consider the fractional Korteweg-de Vries equation $u_t + u u_x - |D|^\alpha u_x = 0$ in the range of $-1<\alpha<1$ , $\alpha\neq0$. Using basic Fourier techniques in combination with the modified energy method we extend the existence time of classical solutions with initial data of size $\varepsilon$ from $\frac{1}{\varepsilon}$ to a time scale of $\frac{1}{\varepsilon^2}$. This analysis, which is carried out in Sobolev space $H^N(\mathbb{R})$, $N \geq 3$, answers positively a question posed by Linares, Pilod and Saut (SIAM J. Math. Anal. 46 (2014), no. 2, 1505-1537).


Composite are generating curiosity and interest in students all over the world.
This project is one of the composite studies to explore the effect of curing temperature
and fiber layer on laminate composite. This project emphasizes on an overview of
composite followed by manufacturing of composite and composite mechanical behavior
testing. The objectives of this project are to fabricate composites with different number
of layer and curing temperature.
Moreover, the effect of composite's thickness and cunng temperature on
structure strength is evaluated. The focus of the study is on the structure made of glass
fiber and epoxy resin followed ASTM D 3039/ D 3039 M using hand lay up technique.
As the result, curing temperature and number of layers does not affect the hardness of
the composite. It remains same for all samples of the composites while in tensile test,
stress and strain of the composite increase with the number of fiber layers in 27°C. To
get the best performance composite, lower temperature is the best curing temperature
with higher number of fiber layers.
You will fmd this project is very interesting. Besides that, it will become one of
an additional references and new knowledge on composite world.


Obstructive sleep apnea (OSA) can be a serious and potentially fatal breathing disorder if left untreated leading to heart arrhythmias, heart failure, high blood pressure, stroke and diabetes [1-5]. This disorder causes a person to experience pauses in breathing due to collapse or blockage of the upper airway during sleep [3,5]. The true cause of OSA can be one or a multiple of the following: the size and position of soft and hard tissue structures of the oro-facial complex, tongue size, soft palate thickness and length, adenotonsillar size, hyoid bone position, short mandibular length, high mandibular plane angle (dolichofacial growth pattern), Class II skeletal and dental malocclusions, and a narrow maxillary arch width, among others [5].


The drying of the leaves of aromatic plants before extraction to reduce moisture content leads to the loss of many compounds which are dragged to the leaf surface by the evaporating water. In this research, the essential oil of Ocimum gratissimum leaves dried by different methods was obtained by hydrodistillation and analyzed by gas chromatography – mass spectrometry. The air-dried, sun-dried and oven-dried leaves yielded 1.33 %, 0.58 % and 0.59 % of the essential oils, respectively, whereas the percentage of oils was 0.61 % in the fresh plant material. The essential oils of O. gratissimum were composed mainly of monoterpenes and sequiterpenes. The percentage composition of major constituents in the dried leaves also varied; air-dried-: caryophyllene oxide (11.84 %), sun-dried-: terpinene-4-ol (17.98 %), and oven-dried-: β–myrcene (12.11 %). The most abundant component in the fresh leaves oil umbellulone (14.68 %) was absent in the dried leaves oils. The yields and chemical compositions of the essential oils obtained from O. gratissimum were affected to varying degrees by the methods of drying used.


Job displacement is widely considered a negative life event associated with subsequent economic decline and depression, as established by numerous prior studies. However, little is known about whether the form of job displacement (i.e., layoffs vs. plant closings) differentially affects depression. The authors assessed the effects of different ways in which workers are displaced on subsequent depression among U.S. men and women nearing retirement. They hypothesized that layoffs would be associated with larger effects on depression than plant closings, particularly among men. The findings generally support these hypotheses. The authors found that men had significant increases in depression as a result of layoffs, but not as a result of plant closings, whereas the reverse was true among women.


Objective:To compare the clinical effect of large-diameter metal-on-metal(L-MoM)total hip arthroplasty(THA)versus conventional metal on poly ethylene(MoPE)THA following posterolateral minimal incision.Methods:22 L-MoM THA in 20 patients were performed with posterolateral minimal incision.A matched group of 22 hips in 20 patients who had undergone a MoPE THA with posterolateral minimal incision were also performed by the same surgeon.The two groups of patients were evaluated clinically and radiographically respectively,including the length of the incision,surgical time,intra-operative blood loss,postoperative drainage volume,postoperative amount of decreasing hemoglobin(Hb),postoperative pain score,C-reactive rotein(CRP),erythrocyte sedimentation rate(ESR),the circumference difference of the operated thighs,length of stay,major complications and component positions.Results:There were no differences between the two groups with regard to the length of the skin incision,operating time,blood loss,postoperative amount of decreasing Hb,the visual analog scale(VAS)pain score at 24 hours after surgery,CRP,ESR,the circumference difference of the operated thighs,length of stay,major complications and component positions.Conclusion:L-MoM THA with posterolateral minimal incision can be effectively performed without increased risk of complications.The key is to master the surgical skills.


Abstract: Alzheimer's disease is a rapidly worsening public health problem. The current lack of effective treatments for Alzheimer's disease makes it imperative to find new pharmacotherapies. At present, the treatment of symptoms includes use of acetyleholinesterase inhibitors, which enhance acetylcholine levels and improve cognitive functioning. Current reports provide evidence that the pathogenesis of Alzheimer's disease is linked to the characteristic neocortical amyloid‐β deposition, which may be mediated by abnormal metal interaction with Aβ as well as metal‐mediated oxidative stress. In light of these observations, we have considered the development of drugs that target abnormal metal accumulation and its adverse consequences, as well as prevention or reversal of amyloid‐β plaque formation. This paper reviews recent observations on the possible etiologic role of Aβ deposition, its redox activity, and its interaction with transition metals that are enriched in the neocortex. We discuss the effects of metal chelators on these processes, list existing drugs with chelating properties, and explore the promise of this approach as a basis for medicinal chemistry in the development of novel Alzheimer's disease therapeutics.


The development of a country can be determined by estimating the health status of children in that country. Their nature and solitude are the responsibility of the nation. Child health is at the core of India's development agenda. According to WHO, Passage of three or more than three loose of stool or watery stools per day or stools more frequent than normal for a child is considered as diarrhoea. Aims and Objectives: To assess the pretest knowledge on home care management of diarrhoea among mothers of under five children, to evaluate the effectiveness of structured teaching programme on knowledge of home care management of diarrhoea among mothers of under five children, to find out association between pre-test knowledge scores on home care management of diarrhoea among mothers of under five children with selected socio demographic variables. Methods and materials: The present study is a quantitative study conducted to assess the effectiveness This study has been carried out in the selected anganwadies at, Kollam District. And study duration was one month January 2021, with structured teaching programme on knowledge of home care management of diarrhoea among mothers of under five children. The study was well designed to with an informed consent form, method of data collection, parameters to be collected and steps to be followed in reviewing the collected data. Non probability purposive samplingtechnique was used to select 60 mothers of under five children for the study. The tools used for data collection were demographic data, structured knowledge questionnaire. All the study plan was submitted to the Institutional Ethics Committee (IEC) for approval of the study. Conclusion: The study showed that there was improvement in the knowledge of home care management of diarrhoea among mothers of under five children after conducting structured teaching programme and thus structured teaching programme was statistically significant at 0.01 level (t = 21.09, p < 0.00). There was no significant association found between mean pretest knowledge score with socio demographic variables. Hence the study suggested that structured teaching programme was effective in improving the knowledge of mothers of under five children regarding home care management of diarrhoea.


This study evaluates the impact of a student program for mentoring incarcerated persons. Mentoring has multiple goals for both incarcerated persons and mentors; this article focuses on its contributions to incarcerated persons. The program encourages incarcerated persons to think positively and constructively, apply anger management, and learn about the normative society they will enter. Twenty-one incarcerated persons participated in semi-structured in-depth interviews in this qualitative research. The findings show that the students eventually became significant others for the incarcerated persons, most of whom reported on forming excellent relations with the students, and learning to act more deliberately and less violently due to the students. They also described reducing their self-absorption, expanding their horizons, and better understanding their criminal choices. Some mentioned acquiring more structured worldviews and improving their behavior. The findings point to significant benefits gained from the incarcerated person–student interaction in the mentoring framework, and the importance of expanding the program.


The narrow sense of oral ulcer has various types as recorded in ancient literatures. The pathogenic factors of it include exogenous wind-heat,upper invasion of toxin,heat of heart and spleen,weakness of spleen and stomach,fire excess from yin deficiency,fire float due to kidney-yang deficiency,heat in the upper and deficiency in the lower etc.As to the therapeutic methods,relieving exterior syndrome and purging heat,clearing away heat and removing toxicity,tonifying qi and spleen,removing fire through nourishing yin,soothing the nerves and nourishing blood,warming kidney-yang were applied separately. Besides,according to ancient literatures,drugs application,mouthwash,bloodletting,acupuncture and moxibustion,Tao yin,and pediluvium were also adopted under certain circumstances.


The purpose of this study was to examine the relationship between goal orientations and perceptions of the motivational climate emphasized by parents, peers, teachers and sporting heroes for children in physical education (PE). Additionally, gender differences in goal orientations and perceptions of the motivational climate were examined. A total of 266 male and female secondary school PE pupils from the United Kingdom completed a survey assessing personal goal orientations for PE and perceptions of the motivational climateemphasized by parents, peers, teachers and sporting heroes. Results indicated that goal orientations were related to these perceptions. Specifically,task orientation was related to perceptions of a learning-oriented climate from parents, peers and teachers and to perceptions of a mastery orientationinsporting heroes. In contrast, an ego orientation was related to perceptions of a comparison climate from parents, peers and teachers, and to perceptions of an ego orientation in sporting heroes. Results are discussed in terms of the implications that the influence of significant others might have for intervention efforts designed to enhance the quality of youngsters' motivational development in PE.


We study the fourth fundamental form of the factorable hypersurface in the four dimensional Euclidean space . We obtain I, II, III, and IV fundamental forms of a factorable hypersurface.


A prospective clinical study was conducted between January 1991 and June 1992 of 92 HIV seropositive patients attending the Adult Outpatient Clinic of the San Juan de Dios General Hospital in Guatemala City. 52 of the patients met the US Centers for Disease Control clinical criteria for AIDS. Limitations in the diagnostic and laboratory facilities of the hospital hampered identification of some opportunistic infections. 74 of the 92 patients were male. 3 of the 18 infected women gave birth during the study period; the status of their children is not yet known. 87% of the cases were in adults aged 18-40. 25 of the patients died during the 18-month study period and 9 were lost to follow-up. 57 of the 92 had lived in the US or Mexico. 43 of the 74 men reported homosexual relations. 6 reported use of intravenous drugs. 3 had received blood transfusions as the only known risk factor. 56 had histories of sexually transmitted diseases. 3 patients reported always using condoms, 57 never did so, and the rest did so occasionally. 52 of the patients had opportunistic infections. 18 had proven and 5 had presumptive extrapulmonary mycobacteria, probably tuberculosis. 2 had salmonella in the blood. 4 had presumptive cytomegalovirus, 6 had chronic mucocutaneous herpes, and 3 had presumptive HIV encephalopathy. 12 had esophageal candidiasis, 6 had extrapulmonary cryptococcosis, and 14 had pneumocystis carinii pneumonia. 13 had proven intestinal cryptosporidiosis, and 1 each had presumptive cerebral toxoplasmosis and extraintestinal strongyloidiasis. 3 had proven Kaposi's sarcoma and 1 had proven immunoblastic lymphoma. 10 had HIV-related weight loss.


Abstract The first human phaeochromocytorna cell line KNA was tested with regard to stimulation of dopamine biosynthesis by nicotinamide adenine dinucleotide (NADH). Differently from rat phaeochromocytoma cells - clone PC12, where NADH increased dopamine biosynthesis significantly, no stimulation in KNA cells was found. NADH is effective on speeding up the formation of the active cofactor tetrahydrobiopterin by a recycling pathway via the dihydropteridinreductase system. Another way of formation of tetrahydrobiopterin is the induction of de novo synthesis by cytokines such as interferon-y or by lipopolysaccharide via activation of GTP cyclohydrolase I, as shown in rnacrophages. Neither rat PC12 nor human KNA cells showed in vitro a stimulation of tetrahydrobiopterin de novo synthesis by interferon-y and/or lipopolysaccharide.


Today, construction is essential to every economy since it employs many workers and significantly contributes to GDP. The construction industry's efficiency has lagged behind other industries for decades due to low productivity, a lack of research, and poor adoption of advancements. Fortunately, the successful development of digital technologies such as Digital Twin (DT) has facilitated growth in many sectors, and DT has the potential to address challenges in building construction projects. While DT is a virtual replica that provides real-time data and analysis of a physical asset to optimize its performance, Building Information Modeling (BIM) is a collaborative process for creating, managing, and exchanging information throughout a construction project. BIM is the most efficient way to create an accurate, high-value DT and support industry transformation. An integrated DT and BIM platform can improve building design, construction, and performance in the architecture, engineering, and construction (AEC) sectors. Based on a literature review, this research aims to clarify and differentiate DT from other advanced 3D modeling technologies, such as BIM. Related publications from articles about DT and BIM in the construction industry were selected, identified, and organized after careful research of the relevant scientific databases. The research has three primary objectives: (1) to examine the present applications of DT and BIM in the construction industry; (2) to emphasize the similarities and differences between the two; and (3) to develop solutions and design methods for BIM and DT integration in building construction.


21 We present in situ secondary ion mass spectrometry (SIMS) and electron microprobe 22 analyses of co-existing garnet, omphacite, phengite, amphibole, and apatite, combined with 23 pyrohydrolysis bulk-rock analyses to constrain the distribution, abundance, and behavior of 24 halogens (F and Cl) in six MORB-like eclogites from the Raspas Complex (Southern Ecuador). 25 In all cases concerning lattice-hosted halogens, F compatibility decreases from apatite (1.47–3.25 26 wt %), to amphibole (563–4727 μg/g), phengite (610–1822 μg/g), omphacite (6.5–54.1 μg/g) 27 and garnet (1.7–8.9 μg/g). The relative compatibility of Cl in the assemblage is greatest for 28 apatite (192–515 μg/g), followed by amphibole (0.64–82.7 μg/g), phengite (1.2–2.1 μg/g), 29 omphacite (<0.05–1.0 μg/g) and garnet (<0.05 μg/g). Congruence between SIMS-reconstructed 30 F bulk abundances and yield-corrected bulk pyrohydrolysis analyses indicates that F is primarily 31 hosted within the crystal lattice of eclogitic minerals. However, SIMS-reconstructed Cl 32 abundances are a factor of five lower, on average, than pyrohydrolysis-derived bulk 33 concentrations. This discrepancy results from the contribution of fluid inclusions, which may 34 host at least 80% of the bulk rock Cl. The combination of SIMS and pyrohydrolysis is highly 35 complementary. Whereas SIMS is well suited to determine bulk F abundances, pyrohydrolysis 36 better quantifies bulk Cl concentrations, which include the contribution of fluid inclusion-hosted 37 Cl. Raspas eclogites contain 145–258 μg/g F and at least 7–11 μg/g Cl. We estimate that ~95% of 38 F is retained in the slab through eclogitization and returned to the upper mantle during 39 subduction, whereas at least 95% of subducted Cl is removed from the rock by the time the slab 40 equilibrates at eclogite facies conditions. Our calculations provide further evidence for the 41 fractionation of F from Cl during high-pressure metamorphism in subduction zones. Although 42 the HIMU mantle source (dehydrated oceanic crust) is often associated with enrichments in Cl/K 43 and F/Nd, Raspas eclogites show relatively low halogen ratios identical within uncertainty to 44 DMM. Thus, the observed halogen enrichments in HIMU ocean island basalts require either 45 further fractionation during mantle processing, or recycling of a halogen-enriched carrier 46 lithology such as serpentinite into the mantle. 47 48


1. King JC, Brown KH, Gibson RS et al. Biomarkers of nutrition for development (BOND)-zinc review. J. Nutr. 2015; 146: 858S–85S. 2. Kogirima M, Kurasawa R, Kubori S et al. Ratio of low serum zinc levels in elderly Japanese people living in the central part of Japan. Eur. J. Clin. Nutr. 2007; 61: 375–81. 3. Gammoh NZ, Rink L. Zinc in infection and inflammation. Nutrients. 2017; 9: 624. 4. Saibara T, Maeda T, Onishi S et al. Depressed immune functions in the early phase of varicella-zoster virus reactivation. J. Med. Virol. 1993; 39: 242–5. 5. Field CJ, Johnson IR, Schley PD. Nutrients and their role in host resistance to infection. J. Leukoc. Biol. 2002; 71: 16–32. 6. Shishkov S, Varadinova T, Bontchev P et al. Complexes of zinc with picolinic and aspartic acids inactivate free varicella-zoster virions. Met. Based. Drugs. 1996; 3: 11–4. 7. Prasad AS, Beck FWJ, Bao B et al. Zinc supplementation decreases incidence of infections in the elderly: effect of zinc on generation of cytokines and oxidative stress. Am. J. Clin. Nutr. 2007; 85: 837–44. 8. Read SA, Obeid S, Ahlenstiel C et al. The role of zinc in antiviral immunity. Adv. Nutr. 2019; 10: 696–710.


Crowd sensing is an effective zero-cost method to map physical spatial fields by exploiting sensors already embedded in smartphones. The potentially huge amount of generated data and random measurement positions represent serious challenges to be addressed. In this paper we propose a combined Gaussian process (GP)-State space method for crowd mapping whose complexity and memory requirements for field representation do not depend on the number of data measured. The method is validated through an experimental campaign involving a high accuracy positioning system and a magnetic mobile sensor as data collector.


In this paper we resolve a conjecture of Weiner (1987) concerning the existence of the so-called pseudomoments for a random vector which belongs to the generalized domain of attraction of an operator-stable law. The proof is a direct consequence of the spectral decomposition theorem for generalized domains of attraction in Meerschaert (1991)


Mayor opened the study session of the Sammamish City Council at 6:30 p.m. Public Comment This is an opportunity for the public to address the Council. Three-minutes limit per person or 5 minutes if representing the official position of a recognized community organization.


The thesis defines design and development of a Pressure Actuation Mechanism for land based munitions. This mechanism employs rubber pads for actuation. A consistent and effective rubber compound needs to be used to achieve the desired mechanical properties .Therefore proper selection of rubber pads through analytical and experimental processes is proposed. In use of rubber pads for actuation, physical and chemical properties play vital role. By using Sponge Rubber (NR+SBR), the thesis aims to study the effectiveness of the developed rubber pads for the actuation mechanism to be used in land based munitions. During the research the analysis was done firstly using experimental method and then was cross checked with FEA method for confirmation of result.


China is marching into a new era that will construct a well-to-do society.The current system of basic education financing was formed in the 1980s.This financing system has many problems in the new era.It needs institutional change as the institutional environment has changed.The author analyses the problems of current financing system in three aspects:the responsibility of governments at different levels,the conflict between the mission of public school and multi-channel investment,the cost of monitoring of school and incee system.On the basis of the analysis the author provides his new thoughts on the basic education financing.


Studies on purple stain of soybean. (1) Effect of various fungicides on the disease and influence of moisture on the occurrence of diseased beans. Mari MURAKAMI, Hiroshi IKEDA, Daizaburo YOSHIMURA and Satamasa YOKOYAMA (Fukuoka Agricultural Experiment Station, Chikushino, Fukuoka 818)Seed disinfection by Benlate-T raised the rate of emergence of soybean and prevented occurrence of disease on the cotyledons. Topsin-M and Benlate applied during growth period reduced the percentage of diseased beans. Thus purple stain can be controlled by the application of Benlate or Topsin-M in addition to the seed disinfection. The rate of diseased beans was higher in wet pods than in dry ones. By a moisturizing treatment, symptoms appeared on beans which had been apparently healthy under dry conditions. These results suggest that moisture is closely related to the occurrence of diseased beans and the appearance of symptoms.


The water constructions used to be designed to meet the needs of function but not to the requirements of environment and people.With the development of the water conservancy projects,the water constructions turn buildings into landscape.The landscape design of the project integrates the architectural art and the hydraulic engineering to enrich the design ideas while meeting the demands of a changing society.Considering water conservancy function,the new type of landscape hydraulic engineering intends to gain attention from colleagues in the industry therefore promoting the development in an all-round way of the water conservancy.


Since March 2013, avian influenza H7N9 virus has caused human infections with resulting in an estimated 30% case fatality rate. Although there has been no evidence of sustained human-to-human transmission, effective medical responses and preparedness should be implemented including developing vaccines. Using the hemagglutinin (HA) of A/Anhui/1/2013, a prototype virus recommended for the H7N9 vaccine development by the World Health Organization, we investigated the effects of HA glycosylation on the growth kinetics and immunogenicity of recombinant viruses that generated in the backbone of a 2009 pandemic H1N1 virus. Glycosylation at HA residue increased viral growths both in cultured cells and in fertile chicken eggs whereas deglycosylation at HA residue decreased them all. When HA glycosites were utilized together, the virus exhibited the greatest replication property. In the hemagglutinin inhibition assay using guinea pig antisera raised against each virus. These antisera showed 1.75- to 4-fold increased immunogenicity across all of the tested viruses. Considered all, these results suggest that specific HA mutation can increase potential of a H7N9 vaccine virus by enhancing growth and immune properties.


Porcelain veneer restoration often require modification at laboratory and chair side prior to cementation .Common adjust -  ments include contour, occlusion , color correction , and special characterization masking of imperfections and final glazing. The purpose of this study to compare surface roughness of polished, glazed porcelain with ceramic based zirconium. Thirty samples {Twenty porcelain specimens resembling flat-back facing (Metal porcelain buttons) of vita ceramic and ten specimens of ceramic based zirconium } were fabricated according to the manufacturer's Instructions.(prepared with dimension of (10mm) in diameter and (2mm) in thickness). The specimens were divided into three groups according to the type of surface treatment tested .Each group consisted of ten specimens and the groups were distributed as follows:- - Group A: Polished unglazed porcelain with Rubber wheel. - Group B: Glazed ceramic based Metal. - Group C: Glazed ceramic based with zirconium. The surface roughness evaluation of the specimens was carried out by a surface roughness analyzer device (profilometer). Statistical analysis of data using (ANOVA- one way test) indicated high significant differences among the tested groups. The highest roughness value was scored by group A (porcelain polished with rubber wheel ) followed by group B ( glazed ceramic based Metal.) then group C ( glazed ceramic based zirconium). - Group (A) showed statistical significance in comparism to group (B). - Group (A) showed high statistical significance in comparism to group(C) -Group (B) showed statistical significance in comparism to group(C). According to the conditions under which this study was carried out, it may be concluded that mechanical finishing, polishing procedures were not able to provided a surface as smooth as the glazed surface for the tested porcelain.


Three topic areas relevant to the database community are identi ed. First is user-centered information analysis environments for correlation and manipulation of multimedia and complex information resources based on semantic content, visualizing complex and abstract information spaces, value-based ltering, and search, retrieval, and manipulation of multimedia and complex documents. Second is scalable, secure, and interoperable information repositories supporting a wide range of information resources and services. Issues to be addressed include: registration and security of information resources and services, access control and rights management, automatic classi cation and federation, and distributed service quality assurance facilities. Third is the intelligent integration of information. This topic area will be jointly funded by the I3 program of DARPA/ISO. Proposals are sought for the de nition, development, demonstration, and application of technologies to enable the intelligent search, retrieval, ltering, integration, abstraction, monitoring, and update of information from large collections of heterogeneous data sources, such as knowledge bases, structured databases, semi-structured documents, and unstructured text, image, and video les. Details of the program can be found at http://www.ito.darpa.mil/Solicitations. Proposal abstracts were due 12/23/96, and full proposals are due 02/26/97.


To evaluate the natriuretic effect of a nonhypotensive dose of felodipine, 11 healthy volunteers (age: 21–28 years) on a high‐sodium diet received the drug or its vehicle in a double‐blind, randomized, crossover study. Administered intravenously at a dose level of 7.5 μg/min for 30 minutes followed by 5 μg/min for 120 minutes, felodipine increased natriuresis (546 ± 69 vs. 454 ± 39 μmol/min, P <0.001) and diuresis (8.9 ± 0.6 vs. 7.5 ± 0.5 mL/min), compared to its vehicle. Renal plasma flow tended to be augmented, but there was a significant reduction of renal vascular resistance (0.085 ± 0.004 vs. 0.101 ± 0.012 mm Hg/mL/min, P <0.03). The glomerular filtration rate was slightly decreased and proximal sodium reabsorption was diminished with no measurable effect on distal function. Felodipine stimulated plasma renin activity, but produced no changes in plasma atrial natriuretic factor, cGMP, aldosterone, and atrial vasopressin levels. In conclusion, felodipine induced natriuresis and diuresis while reducing proximal tubular sodium reabsorption.


At the Supcrcomputing Research Center we have built a computing farm consisting of 16 SPARCStation. ELCs. The ELCs all support the Mother distributed shared memory, which has primitives to support efficient synchronization and use of the network and processors. Mother docs not support the traditional consistency semantics provided by, for example, Ivy or Mach external pagers.

The first parallel application we ran on the farm was a Monte Carlo radiative heat transfer simulation. The performance we achieved on the farm was within an order of magnitude of the performance we would expect to achieve on a 16-processor model of the C90 supercomputer available from Cray Research.

With this application we found that the use of the Mother distributed shared memory allowed us to run the same code on the Cray as we ran on the SPARCStatlons, and we did not require the complex cache-coherent memory semantics provided by, say, Ivy or Mach to run this application effectively.


Abstract The synthesis of the potential ligands, cyclamphosphane sulfide and cyclamphosphane selenide, is described. Products are characterized by elemental analysis, infrared, 31P NMR and mass spectrometries.


taking the lead in conducting the study for the group. The sponsors have established the Health Care Cybervision web site to provide access to a questionnaire that will provide the critical data for the second and third phase of the project. Healthcare professionals are invited to visit the site at http://www.hccybervision. com and complete the questionnaire. All participants will receive the three monographs produced by the project. The first, available now, presents the framework and scope of the project. The second will detail the findings of the survey and examine the Internet's emerging impact on the healthcare industry. The third and final monograph will examine and document opportunities and barriers to the use of the Internet in health care in the future. The sponsors believe that this project will provide a truer picture than is currently available of how the Internet is being used in health care today, and give new insight into how it can be best used in the future.


When you have a strong team, you can provide quality mental health care and have an immensely satisfying career—even in the middle of a cornfield.


This paper suggests a Resource Description Framework (RDF) model for effective handling of distributed data relating to the Semantic Web. RDF is a data model that integrates aptly structured data. The World Wide Web is facing great challenges in data retrieval as a result of increase and request of knowledge from different sources. This brings the issue of information overload. Therefore, in minimizing this challenge, the paper presents the process of modeling RDF knowledge base which is the essential step of Semantic Web development. As a state-of-the-art research, a meteorological and oceanographic dataset has been used to provide the basic concepts of RDF serialization. The result accessed through the developed SPARQL endpoint. Thus, it implies that the approach is sufficient for querying as well as data representation of distributed data.


Anodized TiO2 nanotube arrays have important applications in the area of photocatalysis and biomedicine. In this study, with the aim of improving the photocatalytic and biomedical properties of TiO2 nanotube arrays, we prepared both single and double layer walled TiO2 nanotube arrays and subjected them to hydrothermal treatment in strontium acetate solution. It was found that fluoride doped SrTiO3/TiO2 nanotube arrays could be formed after hydrothermal treatment without the failure of the single and double layer walled structure. In the case of fluoride doped SrTiO3/TiO2 nanotube arrays with a double layer walled structure, doping of fluoride induced a visible light response, formation of SrTiO3 benefited the separation of photogenerated electron–hole pairs, and the double layer walled structure led to an enlarged surface area. Due to the synergetic effect of above three factors, the fluoride doped double layer walled SrTiO3/TiO2 nanotube arrays demonstrated the highest photocatalytic activity under ultraviolet, visible and simulated solar light irradiation. The degradation rates of methylene blue solution are 0.13 h−1, 0.26 h−1 and 0.53 h−1 respectively. Moreover, ability to induce hydroxylapatite formation on the surface was also examined through an immersing test in simulated body fluid. The results indicated that SrTiO3, doped fluoride and a double layer walled structure could stimulate the hydroxylapatite formation by providing a larger number of hydroxyl ions, hydroxyl radicals and reactive initiation sites, thus the fluoride doped double layer walled SrTiO3/TiO2 nanotube arrays also exhibited the best ability to form hydroxylapatite on the surface.


A no doubt far from immaculate conception of how it, er, must have been, in Paris, almost fifty years ago, with Beckett, just a few weeks before he was awarded the Nobel Prize for Literature.


The use of computer for a long time period can cause a ocular complaints called Computer Vision Syndrome (CVS). This syndrome can be influenced by various risk factors, such as individual factors, computer factors and environmental factor. This study is to identify and analyze individual, computer and environmental factors associated with the incidence of Computer Vision Syndrome (CVS). This research is an observational study with a case control method. The study was conducted in September-October 2018 at General hospital Haji Surabaya. A sample of 266 people with certain criteria, divided into 2 groups of cases and controls. The research was conducted by direct interview using a questionnaire. The statistical test uses the Chi square test. The odds ratio used to determine the value of the association of the magnitude of the risk and multivariate analysis (logistic regression analysis) is used to find out which risk factor is the most influential. The 95% confidence interval and the results of the case-control study observations are arranged in a 2×2 table. The factors that were significantly associated with the incidence of CVS were gender [p = 0.009; odd ratio = 0.504 (95% CI = 0.301 – 0.843)], use of glasses [p = 0.000; odds ratio = 0.333 (95% CI = 0.201 – 0.553)], duration of working hours on the computer [p = 0.000; odds ratio = 0.331 (95% CI = 0.194 – 0.563)] and computer vision distance [p = 0.000; odds ratio = 0.331 (95% CI = 0.194 – 0.563)].


Staphylococcus, Bacillus, Pseudomonas, Citrobacteria, Klebsiella, Rhodococcus, Rhodotorula and Pichia are the commonly used microorganisms in bioremediation processes which include bio-augmentation wherein microbes and nutrients are added to supplement the intrinsic microbes of the site for bio-stimulation or sometimes nutrients and enzymes are added to supplement the intrinsic microbes of the site. These metal contaminants pose adverse health effects on those who live near the polluted sites. It has already been established that heavy metals and heavy metal toxicity possess serious threat to our environment leading to severe health hazards which may even claim our lives. Thus considering this acute environmental problem and environmental sustainability, our research interest has prompted us to intensify our study on bioremediation of heavy metals (lead and chromium) by using heavy metal resistant microorganisms. Keeping this view in mind, the present work has been undertaken to isolate and identify the heavy metal tolerant microorganisms and a heavy metal tolerant/resistant yeast strain (Rhodotorula mucilaginosa) was isolated from effluent of Chittaranjan Locomotove Workshop,W.B.


Drax power station comprises 6 660 MW bituminous coal-fired units with an annual coal consumption of 11 milion t. This paper explains the project strategy for the retrofitting operation. The FGD system is briefly described


In this paper, the fundamentals of a prospective Internet that aims to collect electric charge of virions at streets is presented. The purpose of this paper is twofold: (i) In one hand to demonstrate the capability of sensors that can be able to detect and identify at the shortest periods of time, the volume of virus in certain public zone. While the wind velocity might vary the detection of virus in air, the proposal of hardware is basically centered in an architecture composed by a layer of Polymerase chain reaction. In some circumstances this would be improved to attract the negative charge of virus so that this pass through micro wires to a layer aimed to discriminate the noise. Thus, the quantity of collected charge would create pulses whose number is approximate to a concrete value of volume of virus. Thus, this information is uploaded to the network in order to calibrate the best intensities to be radiated at the area of detector.


To the Editor

Smith et al1 make a laudable effort to define medical student learning objectives in laboratory medicine. Most of the listed objectives already exist in medical school curricula, as broadly defined by the US Medical Licensing Examination step 1 content outline for basic science disciplines in general principles and organ systems, in addition to the applicable step 2 and 3 content described by the authors.2 The fundamental issue at the medical student level is depth of knowledge detail required. No curriculum can teach to the expert level on every subject. The true tests for curricular necessity should be clinical relevance, application to patient safety, and …


The Effect of Biological Assessment in Think Pair Share (TPS) Strategy on Students' Cognitive Abilities. The purpose of this study is to find out the differences in students' cognitive abilities, that is, critical thinking and creative thinking, in Think Pair Share cooperative learning model between those given authentic assessment and those conventional assessment. A number of senior high schools in Malang Municipality were involved based on the categories of high and low achievement scores of national examination. Using a 2x2 factorial quasi experimental design, the study selected a sample of eleventhgrade students. The results of ANCOVA, followed by the Least Significant Different (LSD), show that there were differences in cognitive abilities between the students assessed using different methods, authentic and


In this research, a numerically efficient computational procedure for the simulation of pavement structures under the load of rolling tyres is presented. In order to avoid a time-consuming transient finite element computation, an arbitrary Lagrangian Eulerian (ALE) formulation is introduced for the pavement structure. In the ALE frame, the pavement is described in a moved reference configuration, so that the loading of the pavement with a steady state rolling tyre can be described as a time-independent process. For the consideration of the inelastic material behaviour of asphalt in the ALE frame, two different procedures are presented and compared. The developed novel inelastic unsplit ALE procedure is found to be adequate, reliable and efficient. As an example, a pavement structure under the load of a rolling truck tyre is simulated. Stresses, strains and displacements of the pavement structure as well as the effect of different driving velocities of the tyre are evaluated.