Anthropological collections, particularly those of mummies, constitute invaluable material for the reconstruction of human history.Therefore, efforts to protect these museum collections are a priority.These efforts must include particular care and attention in the study of the specimens and application of the most sophisticated techniques to acquire precise information without causing damage. The mummies in the Archaeology Museum of Palmyra are a cultural and biological patrimony of inestimable value for the Syrian city, since they are the only ones remaining after past dispersions. [...]


Cow's milk protein allergy (CMPA) has been reported as one of the common food allergies in infants and young children in literature. CMPA presents with non-specific symptoms leading to over- or under-diagnosis which leads to withdrawal of milk-containing food items from meals of infants and children resulting in under-nutrition and poor growth in some cases. In Benin most cases of 'suspected CMPA' are managed based on parental understanding and very few are properly diagnosed and managed. To the knowledge of the authors, there is paucity of data on CMPA in Nigeria, thus we report a case of a two year old girl with CMPA. Keywords : cow's milk allergy, non-specific symptoms, mis-diagnosis, under-nutrition


Updating component-based systems demand a careful treatment due to stability risks. Replacement components must be analysed on behaviour equivalence for the provided functionality. Our proposal complements the conventional compatibility analysis with black-box testing criteria as a support for substitutability. The aim is to analyse functions of data transformation encapsulated on components, i.e. their behaviour. This is reflected by the observability testing metric. For a piece under substitution, a component behaviour test suite is built for being later applied on candidate replacement components. The approach is supported through a tool, testooj, which is focused on testing Java components.


SAW torque sensor is an important method in torque detection, and sensing element is an important part of sensor. Therefore, the design and analysis of the torque sensing element in SAW technology hold significant importance. In this study, The SAW torque sensing element was simulated and analyzed by finite element simulation software, the SAW torque sensing element was fabricated through the use of MEMS processes. Finally, the SAW torque testing platform was built, and the SAW torque sensing element was tested and analyzed. The results of three loading tests show that the sensitivity of SAW torque sensing element is 4.0045kHz/N•m, 4.0044kHz/N•m and 4.0011kHz/N•m. The results show that the designed SAW torque sensing element has good sensitivity and provide a good guidance for the application of SAW torque sensor.


Abstract : We have investigated whether and how autoimmune complex (AIC) in SLE (lupus) can induce T helper (Th) cell polarizing cytokines including IL-27 and IL-1 , leading to enhanced Th cell responses. We have measured IL-27 gene and protein expression by healthy human monocytes g Istimulated with autoimmune complex containing anti-dsDNA and snRNP antibodies using qPCR and ELISA, respectively. However, levels of IL-27 produced from the stimulated monocytes were relatively low compared to those of the pro-inflammatory cytokine IL-1 . IL-1 promotes of the development of Th17 cells that is increased in lupus patients. Increased IL-1 expression was found in the target tissues of lupus patients although the mechanism for these findings is unknown. It is conceivable that a combination of IL-27 and IL-1 can promote the development of Th17 cells with the capacity to produce IL-10, a notion in accordance with our original hypothesis. We have reported that AIC containing dsDNA and U1-snRNP activate human monocytes dependently of anti-dsDNA and U1-snRNP antibodies, respectively, leading to the production of cytokines including IL-1 . This phenomenon was dependent on the activation of Toll-like receptor and NLRP3 inflammasome pathways. We also found that IL-27 can suppress IL-17 production in human CD4+ T cells and that such suppression is enhanced in patients with SLE. This finding suggests a potential therapeutic implication of exogenous IL-27 in patients with SLE.


Here we describe a new signaling cross‐talk between the Vav/Rac1 and Ras pathways that is established through the stimulation of RasGRP1, an exchange factor for Ras subfamily GTPases. This interaction is crucial for Ras activation in lymphoid cells, since this GTPase cannot become activated in the absence of Vav proteins. The activation of RasGRP1 requires both the generation of diacylglycerol via phospho lipase C‐γ and the induction of actin polymerization, two responses induced by Vav and Rac1 that facilitate the translocation of RasGRP1 to juxtamembrane areas of the cell. Consistent with this, the cross‐talk can be activated by tyrosine‐phosphorylated wild‐type Vav, oncogenic Vav and constitutively active Rac1. Conversely, Ras activation can be blocked in lymphocytes and ectopic systems using inhibitors affecting either phospholipase C‐γ or F‐actin polymerization. These results indicate that a relay mechanism exists in lymphoid and other cells helping in the generation of robust signaling responses by the Rac/Rho and Ras pathways upon receptor engagement.


This essay argues that Gertrude Stein's novella 'Melanctha' (1909) inscribed within the canon of Anglo-American modernism the conceptual coordinates for the emergence of a posthumanist aesthetics. It also argues that the potential of such a radical event can be more fully appreciated by considering Stein's pioneering treatment of meaning in the novella alongside Niklas Luhmann's account of meaning in his theory of social systems. The essay emphasises the details of Stein's crucial contribution to the articulation of a discourse of posthumanism and relates this occurrence to the emergence of a mass-media system at the beginning of the twentieth century.


Poultry farming has always been a means of combating malnutrition. In recent years, quails farming has offered us new choices of taste, with meat production to meet the increased demand in animal proteins. However, the big problem in the poultry sector remains the cost of food. To overcome this problem, the use of agricultural by-products in animal feeding remains capital. These by-products are readily available and rich in nutrients, as it is the case with Adansonia digitata and Parkia biglobosa pulp. This is the context in which this study is taking place, which is a contribution to the valorization of P. biglobosa pulp as a partial replacement for corn in quail nutrition as a source of energy and nutrients. A total of 540 curds was selected with an average body weight of 7.00 ± 0.02 g and one day of age. Four batches of treatments were constituted, namely, batch control, batch 5%, batch 10% and batch 15% according to the rates of substitution of corn by P. biglobosa pulp in their feed. The weekly weighings of the birds made it possible to follow their weight growth and the average weekly gain of the birds. The consumption index was thus determined on the basis of food consumption. The results showed that the substitution of maize by P. biglobosa pulp improved the weight and the average daily gain of the birds in the growth phase. Feed consumption and feed conversion ratio were low for the control batch compared to the treated batches during both rearing phases. Food consumption and the consumption index were more in favor of the control especially in the start-up phase compared to the treated batches. The pulp of P. biglobosa, by virtue of its nutritional quality, can therefore be used in quail feed at corn substitution rates of 5 to 15% without adversely affecting its zootechnical performance.


Inflation is a rise in the general level of prices of goods and services in an economy over a period of time. When prices rise, each rupee buys less goods and services than it had been before, consequently eroding the purchasing power of money. It is measured through inflation rate- the annualized percentage change in a general price index Consumer Price Index and Wholesale Price Index over time. Inflation affects both the economy of a country and its social conditions, as well as the political and moral lives of its inhabitants. Inflation is the gravest economic concern which has gripped India into its jagged tentacles. India has been plagued by the disease of inflation since the 1950s but it has started showing its prominently harmful symptoms and ill effects since 1991, post liberalization since previous year's global meltdown somewhat crippling the Indian economy, the inflation rate has been steadily rising to surpass the double digits. At present, it is hovering around 9 per cent. Present paper is an attempt to understand inflation and its historical development in India.


Purpose

The purpose of this paper is to investigate the effect of laser surface texturing on the tribological properties of polyimide composites and the output performance of traveling wave rotary ultrasonic motor.

Design/methodology/approach

The surface texturing on polyimide composites specimens were fabricated by laser ablation process of different dimple densities, and then the tribological properties were tested by a flat-on-flat tribometer under dry conditions. Finally, the output performance of the traveling wave rotary ultrasonic motor was tested to verify the effectiveness of dimples surface texturing.

Findings

The results show that surface texturing can greatly enhance the friction coefficient of contact interface, especially the specimen with a dimple density of 7.06 per cent exhibited the highest friction coefficient among the specimens. When the input voltage is 500 V, the output power, locked-rotor torque and output torque of ultrasonic motor with textured PI of 7.06 per cent dimple density as friction material at the speed of 100 r/min increased by 13.8, 19 and 12.8 per cent compared to that of the untextured PTFE, respectively. When the ultrasonic motor reverses, the output performance is increased by 20.9, 40.3 and 17.7 per cent, respectively.

Originality/value

Surface texturing is an effective way to improve the friction behavior of polyimide composites and then correspondingly enhance the energy conversion efficiency and output performance of the traveling wave rotary ultrasonic motor.


The main objective of this research is to understand the relationship between budg- etary goal characteristics and managerial performance. However, the positive relationship between procedural justice and managerial performance may not be a direct one, but is indi- rect via the intervening variable of procedural justice. Sampling technique used is purposive sampling with criteria as middle and lower manager on the finance department in local government of ex Karesidenan Surakarta. Analysis technique used is multivariate analysis to test the truth of relationship (causal model) between variables of this research. The result, based on a path analytical model and a sample of 83 middle and low managers on local government, indicate that budgetary goal characteristics have a direct effect on the managerial performance and indirect effect via procedural justice.


Pre- and postoperative treatment with the potent corticosteroid difluprednate ophthalmic emulsion 0.05% signficantly improves outcomes after cataract surgery compared with use of prednisolone acetate ophthalmic suspension 1% and so results in improved patient satisfaction, according to one expert.


SCA which solved the transportability and reusable among different software radio systems is the technique specification of software radio developing.The basic content of SCA specification is introduced,the specification followed by software radio system design is illuminated from hardware,software and security architectures.And then the SCA specification established the foundation of software radio developing.


This article characterised the role of oxidative stress in mediating pathological reactions in the lung and the unique antioxidant defences that the lung possesses. The impact of redox balance in regulating inflammatory and immune reactions were discussed, and the impact of enhancing lung antioxidant capacity in animal models of asthma and chronic obstructive pulmonary disease were characterised.


Tuned Mass Damper (TMD) with magneto-rheological elastomer isolators (MRE-TMD) is a novel control device for suppressing structural vibration caused by earthquakes. It is a nonlinear hybrid vibration absorber and the stiffness & damping can be controlled by changing the current of isolators' coil. Using MRE-TMD as an adaptive frequency TMD to mitigate vibration and treating it as only a passive damper is the focus of most nowadays researches. In this paper, semi-active control theory is introduced to the MRE-TMD-structure system which means that the control force can be obtained through variable stiffness & damping technology, and MRE-TMD is a semi-active damper instead of a passive one. A control system sketch, as well as principles and control strategies of a semi-active MRE-TMD-structure system for vibration control is designed. An improved limited sliding (ILSL) algorithm based on linear quadratic optimal theory is also introduced. Numeric simulations of a five-story benchmark building model equipped with semi-active MRE-TMD subjected to several benchmark earthquake records are conducted to investigate the control performance of the proposed semi-active MRE-TMD. Control force characteristics of the structural MRE-TMD systems are also evaluated. The results indicate that semi-active MRE-TMD can provide control force to the system and it shows superior ability to suppress the structural vibrations of comparing to the passive MRE-TMD.


INTRODUCTION Use of pulverized coal in electric utility power plants has resulted in severe environmental problems due to the emission of sulfur oxides and halogen. In situ sulfur capture, adding the sorbent with coal together, is regarded as the prime candidate because of its low cost and simplification. iJ2), it is also usefu1 for capture of halogen during combustion 3), Among the sorbents, calcium'based are particularly attractive due to their low cost and the inertness of the calcium su}fate or calcium sulfide by'product 2), However, due to many physical and chemical factors, in situ sulfur capture has the low removal efficiency Many works aTe, therefore, still necessary to clarify the behavior of sorbent in coal combustion. This paper mainly fbcuses on SOx and halogen removal ability of limestone in combustion of three coals, Effect of residence time, morphology and mode of occurrence ofcalcium are discussed here. EXPERIMENTAL Coal properties Three coals from China, Yiinzhou with high SulfUr (YZHS), Datong (DT) and


Objective
To evaluate the effectiveness and safety of mushroom incision femtosecond-assisted penetrating corneal transplantation combined cataract extraction surgery.

Methods
A retrospective analysis was carried out for 29 patients (30 eyes) who performed FS- PKP combined cataract extracapsular extraction versus 11 patients (11 eyes) who performed traditional PKP combined cataract extracapsular extraction. Lesions involving whole cornea and all the patients' lenticular opacity were moderate or above. Femtosecond laser was used for make mushroom incision of corneal graft and corresponding recipient bed, conventional group used trephine. Then implemented cataract extracapsular extraction, intraocular lens were implanted, sutured at last. Their follow-up were 1 week, 1 month, 3 months and 6 months, part of the patient were followed up until 18 months. The follow-up results of two groups were compared.

Results
Postoperative vision of two groups had increased, postoperative UCVA and BCVA of femtosecond group were better than normal group, postoperative astigmatism was lower than normal group within 3 months, and there was no obvious difference after 6 months. No obvious difference was found between two groups of ECD and postoperative complications occurrence rate.

Conclusions
Mushroom incision of femtosecond-assisted penetrating corneal transplantation combined cataract extraction surgery has obvious curative effect, precision cutting and high security, its early visual acuity is superior to the traditional penetrating keratoplasty, it can be widely used in clinical therapy.

Key words:
Femtosecond laser; Keratoplasty; Cataract; Penetrating; Leukoma


One of the most used and abused approaches to technology studies in the schools is creative design and technological problem-solving. Current research suggests that it is not clear what students learn, if anything, in many creative design and technological problem-solving activities. Recalling the previous chapters, it is not enough to merely involve students in activities and problems. Emotions, knowledge, and skills must be articulated, organized, and demonstrated. Inferences from mistakes and successes must be drawn. Procedures must be practiced. One of the reasons that creative design and technological problem-solving activities are often without adequate results is that technology teachers tend to take creativity, design and problem-solving for granted. We assume that creativity, design, and problem-solving are automatic components of what we practice in technology studies. However, little is automatic in education. There is more to design and problem-solving than learning methods and resolving technical problems. In this chapter, current research is brought to bear on creative design, ingenuity, and technological problem-solving. In technology studies, one of our missions is to demystify the processes and products of design and technology. It is not enough to merely teach students to express their creativity, design or solve problems. We use the processes of creative design and problem-solving to disclose self-knowledge and feelings as well as the cultural 701 E. Chocolate Avenue, Suite 200, Hershey PA 17033, USA Tel: 717/533-8845; Fax 717/533-8661; URL-http://www.idea-group.com ITB13598 INFORMATION SCIENCE PUBLISHING


The number of obese patients referred to our laboratory for pulmonary function tests is increasing: sleep breathing disorders, unexplained effort dyspnea, evaluations before surgical procedures are the main problems we are expected to cope with. In some patients with normal FEV1 and FEV1/VC values, we have observed an overlap between the tidal volume expiratory flow and the maximal forced expiratory flow, a pattern that suggests expiratory flow limitation (EFL) [1]. EFL has been reported in obese patients without bronchial obstruction [2] and it is not surprising that some of our obese patients may be flow limited at rest. Partial sub-maximal flow/volume curves (PSCs) have been reported as a tool for detecting expiratory flow limitation in patient with airway obstruction [3]. In COPD we described that when PSCs suggest the occurrence of EFL, a loop in the expiratory phase of quiet breathing airway resistance (Raw-qb) is frequently seen. We hypothised that a loop in the expiratory portion of Raw-qb could be a marker of EFL [4]. With the aim of seeing if the same issue was true for obese patients, we studied 45 consecutive obese subjects with no history of asthma, no bronchial hyperreactivity to methacoline challenge, and no acute or chronic obstructive lung disease. Thirteen patients had no graphic overlap between maximal flow-volume curves and tidal volume; the others had tidal volume expiratory flows impinging maximal forced expiratory flows in all manoeuvers, suggesting the likelihood of EFL. The Raw-qb were obtained twice, when a patient was breathing at tidal volume, trying to minimise factors that could artificially create a loop (phase delay in flow measurement, artefacts due to gas temperature changes, air losses from the mouthpiece and cheek movements, plethysmographic losses). After at least eight stable tidal breaths, patients were invited to sligthly increase their respiratory rate to 18-24 breath/minute paced by technician: during this phase Raw qb were collected. PSCs, obtained according to the description by Pellegrino et alii, are extensively described elsewhere [3, 4]. The manoeuvres, were repeated 2-4 times. All measurements were obtained at the same session with patients seated, using the Vmax 20 Sensor Medics. The data was analysed using Systat statistical software, rel. 11.05 for Windows (SPSS Inc. Chicago). The results were expressed as means ± standard deviation and as frequency percentages. The differences in variables between groups were evaluated by Student's unpaired two tailed ttest and ANOVA. The level of statistical significance for each test was set at <0.05. The association between variables was examined using bivariate correlations and Spearman's coefficient calculation.


On the basis of analyzing the status of Vacuum Pressure Impregnation equipment and traditional impregnation method,In accordance with instability of the graphite electrode impregnation control system caused by artificial element,PLC control system of Vacuum Pressure Impregnation is put forward,control precision is improved,and good result is gained in practice.


The lower Wuerhe formation reservoir of the 8th district is a blocky, ultra-low-permeability gravel reservoir with poor waterflooding development, and it is urgent to attack the gas injection gravity flooding. The barrier property of seepage barriers such as interlayers developed inside the reservoir is very important for the study of gas injection gravity flooding. The mineral composition, pore throat structure, and physical characteristics of the interlayer rocks were studied by X-ray diffraction (XRD) whole-rock analysis and nuclear magnetic resonance (NMR). The gas injection breakthrough pressure of the interlayer was studied by core breakthrough experiment and digital core simulation. Based on the determination of the interlayer criteria, logging was used to interpret and characterize the interlayer. The effects of different types of interlayer combinations on gas injection were studied by combining the physical model and numerical simulation methods. The results showed that the lithology of the interlayer in the lower Wuerhe formation of the 8th district was mainly mud-bearing fine gravel with microporosity, average porosity of 6.1% and permeability of 0.0043 mD. The interlayer gas injection breakthrough pressure and permeability were in a logarithmic linear relationship, and the lower limit of gas injection breakthrough under reservoir conditions was 0.003 mD. Initially, it is difficult to flood the upper remaining oil of the gas injection due to the blockage of the interlayer, while in the middle and late stage, the gas-liquid interface gradually reached stability with the increase in injected gas, which has little impact on the final recovery. These results indicate that it is feasible to carry out gas injection gravity flooding in this reservoir.


A Electric Vehicle Micro-computer Control system based on Dual-single chip microcomputer is designed; With Dual-Part RAM to complete data exchange between single chip microcomputers; A basic principle and a completed way on the FPWM is presented. The practical application shows that the system has a simple structure and a strong function. It also shows that the capability to price of this system is very high.


In this work the coating technique adopted for the preparation of zinc oxide thin film is sol-gel spin coating method. The materials used for the fabrication of ZnO thin film are zinc acetate dehydrate, 2-methoxy ethanol and monoethanolamide. The optical characteristics wereanalysed with the help of transmittance spectra obtained from UV -visible spectroscopy. All samples were annealed at different temperatures ranging from 35°C to 75°C. When analyzing it is found that the optical characteristics are strongly depend on the annealing temperature. The transmittance is maximum above 400nm wavelength for all samples and it is about 80% from 400nm to 800nm. When analyzing the absorption spectrum it is also found that the absorption coefficient is also depends on annealing temperature. The optical band gap is found decreasing when annealing temperature increases.


Abstract: Recently we reported the isolation and partial biochemical characterization of a novel polypeptide, h3, from the human brain and liver. Thin‐layer isoelectric focusing showed that the polypeptide was ubiquitously distributed throughout the human brain. Immunophosphatase transfer electrophoresis showed that this protein was localized in several mammalian species and different tissues. In addition, h3 or h3‐like protein was demonstrated in subsets of tissues from one avian species. Protein h3 was present in epithelial and muscular tissue, as well as in nervous tissue; however, for all species investigated, it was most abundant in CNS and muscle.


Fungal infection on the seed adversely affects the seed quality, causing seed discoloration, reduced seed weight and density, poor germinability and reduced viability. Seed mycofora load on five cultivars of brinjal viz., GOB-1, Doli-5, GAOB-2, GABH-3 and ABH-1 was studied and Alternaria tenuis, Fusarium oxysporum, Aspergillus niger, A. flavus, Curvularia lunata, Penicillium sp. and Phoma sp. were found associated with seeds. Among all cultivar GOB-1 had highest number of seed mycoflora. Seed treatment of systemic and non-systemic fungicides of the cultivar GOB-1 seeds with carbendazim, tricyclazole, tebuconazole, thiram, captan and mancozeb at their respective concentrations revealed significant differences in per cent seed mycoflora. All the treatments reduced the seed mycoflora but none of the treatments gave complete control of all fungi. However, minimum number of fungal species (three) were recorded with thiram at 0.3 per cent with minimum per cent seed mycoflora (6.25%) followed by carbendazim at 0.1 per cent and tebuconazole at 0.1 per cent. Among all the fungicides, highest per cent seed mycoflora was observed with mancozeb at 0.3 per cent.


With the rapid development of renewable energy, there is a shortage of renewable energy consumption, resulting in serious waste of resources. Relying solely on technological improvement can no longer meet the large-scale consumption demand of renewable energy, and market-based measures are needed to further promote the consumption of renewable energy. Nowadays, China has established multiple market mechanisms. In order to measure the market mechanism's contribution to the renewable energy consumption effectively and guide the adjustment of the market mechanism, a comprehensive evaluation system needs to be constructed. Therefore, this paper first determines each evaluation index of the evaluation system from the three aspects of power generation side, power grid side and social side, and then proposes the concept of influence degree, which is used to form the evaluation index value. Then the evaluation is established based on the improved entropy method and ideal solution. Finally, taking the measures of developing auxiliary power service market in Fujian Province and other regions as an example to evaluate its impact on the renewable energy consumption, which proves that the method used in this paper has application value in evaluating the effect of the operation mechanism of the power market.


Realistically useful level 10 W m−2 electric power generation is demonstrated during liquid cooling of a heat releasing surface using a thin thermal boundary layer and thermally stable electrolyte flowing between non-isothermal electrodes.


Opening words from chair of the Northern Research Forum Steering Committee, Lassi Heininen. Recorded by Arctic Portal at the 6th NRF Open Assembly in Hveragerði Iceland, 4. - 6. September 2011.

Please click on the URL below to see the video.


The British Library was founded in 1972 by an Act of Parliament which brought together eight institutions, including the British Museum Library and the National Lending Library for Science and Technology. The Library has a 250-year history of collecting, with over 150 million items from oracle bones to digital ephemera. Our traditional strength is in arts and humanities, but, in 2006, the Library decided to invest in the development of its social science proposition. Activity to date has concentrated on creating a new department, developing relationships with the research community, alongside the identification and mapping of material across the Library (by discipline and research themes) and creating a coherent social science collection. Collaboration and the development of relationships with the wider social science research community are key priorities as we aim to play a significant role in knowledge transfer, particularly the exchange of ideas and experience between researchers, practitioners and policy makers. Engaging with the public is a longer term goal, with the intention of highlighting the role and value of research. This paper discusses the process and issues involved in developing the social science proposition and moving from a collection to content-focused approach in a major national research library. International Federation of Library Associations, Social Science Libraries Section, Satellite Conference, Disappearing disciplinary borders in the social science library global studies or sea change? University of Toronto, Toronto, Canada, 6-7, August 2008 Collection or content? Developing a social science proposition in the British Library 2 IFLA Social Sciences Libraries Section, Satellite Conference Disappearing disciplinary boundaries in the social science library – global studies or sea change? Collection or content? Developing a social science proposition in the British Library


By comparing to the multiple echelons of China-foreign football club,this paper finds out the gap location with foreign soccer club and suggests the development countermeasure of Chinese soccer club. At the same time,the author hopes that can provide draw lessons for our country's soccer club.


BACKGROUND
Sensitization patterns to dust mites depend on the geographic area and are important in clinical practice. However, the role of molecular diagnosis is not currently defined. We sought to characterize a pediatric population focusing on sensitization to different mite species and major mite components, to assess the clinical relevance of sensitization to allergenic components in our practice.

METHODS
Consecutive children with respiratory allergy sensitized to house dust mites by skin prick test were recruited. Specific IgE to nDer p 1, rDer p 2, rDer p 23 by ImmunoCAP, and sIgE by ImmunoCAP-ISAC microarray was determined. Subjects were followed-up for three years.

RESULTS
A total of 276 children were recruited. Sensitization was 86.6% to nDer p 1, 79.3% to rDer p 2 and 75.8% to rDer p 23. Lepidoglyphus was the most common storage mite detected by SPT. Twenty-six patients (9.4%) were not sensitized to Der p 1 and Der p 2; noteworthy, 14 of them (53.8%) had positive IgE binding to Der p 23. Asthmatic patients, and especially those with a persistent moderate and severe phenotype, recognized more often the three major allergens.

CONCLUSIONS
Most of our population with mite allergy is sensitized to Der p 1, Der p 2 and Der p 23 major allergens; however, 5% were sensitized only to Der p 23 of the allergens evaluated. Sensitization to Der p 23 should be considered in the diagnosis and treatment of mite allergy, especially in patients with moderate and severe asthma because it may worsen the clinical phenotype.


With a variety of tourism resources,more tourist facilities and multiple trades,the integrated tourist attraction is a typical carrier of circular tourist economy.The circular economy development of integrated tourist attraction should not only stick to the principles of reduction,reuse,recycling,replacing,reintegration and rethinking;but also be organically combined with tourism environment protection,resources cultivation,products innovation,image advancing,and tourism benefit enhancement.Its sustainable development should be based on ecological restoration,culture inheritance,energy consumption reduction and green production.


Foreign sera, their globulin fraction, or washed immune aggregates containing foreign immune globulin were tested for their ability to evoke antibody formation against their immune globulin components. The antibody response against immune globulin was measured by two agglutination methods. In one of these sub-agglutinating amounts of the foreign immune globulin were adsorbed on red cells; in the other the foreign immune globulin against polysaccharide, obtained by dissociation of immune precipitate, was adsorbed to tanned red cells.
 The data show that guinea pigs injected with normal rabbit serum or its globulin fraction fail to produce appreciable amounts of antibody against rabbit immune globulin. In contrast, injection into guinea pigs of washed immune aggregates formed by the reaction of rabbit immune sera with their corresponding antigens elicits production of potent anti-rabbit immune globulin sera. The ability of washed immune aggregates to evoke this antibody response is inhibited by the admixture of normal rabbit serum to the immunizing antigen. Strong immune sera against the immune globulins of mice and guinea pigs are also readily produced by the injection of immune precipitates containing mouse or guinea pig immune globulin into guinea pigs or rabbits, respectively. Practical and theoretical implications of these findings have been discussed.


The documents on the administration of career education which are listed here were screened from a computer search of the ERIC collection. All are available in either microfiche (MF), &dquo;hard copy&dquo; (HC), or from the producer of the document. flAdeA3 [on MF and HC 3kou2d be sent to ERIC Document Reptoduction SeAvice, P.O. Box J 90, Ah.2,ca2g~av~, V1Bgln1a 22210. For additional information on the administration of career education, consult the pages of ERIC's R&60u~.c.&6 in Education (RIE) and CuBAent Index to Jocvc~.a.~S .cn Education (CIJE) or write or call the ERIC Clearinghouse on Career Education, The Center for Vocational Education, 1960 Kenny Road, Columbus, Ohio 43210 (614) 486-3655.


Delicate degree of wheatstone bridge is an important factor that affects its measurement precision. This paper discusses the relation between delicate degree and electricity resistance value of bridge arms of wheatstone bridge from the perspective of theory and experiment with the conclusion reached which shall benefit the improvement of delicate degree and the teaching of such experiment.


In order to reduce the tropospheric delay error and improve the positioning accuracy of GPS, the feasibility was discussed of tropospheric delay calculation by prediction model. Four kinds of prediction model were established, which are multivariate linear regression model, combination forecasting model, grey model and BP neural network model. And a new method of calculating weight coefficient of the combined model was invented. With reference of the CORS observation data and ground meteorological data from Pizhou and Xinyi station, an experiment was carried out to compute tropospheric delay. The experimental results showed that, within 48 h, the accuracy of four forecasting model respectively were 10,15,25,30 mm. Among which the multiple linear regression model was the best regards to predictive effect. Its prediction accuracy could reach 1 cm if the true value of learning samples was known, which was improved about 50% compared with the traditional model of tropospheric delay correction.


The expenditure of the Community budget is composed of many chapters and headings. All of these are classified in six titles/heading budget sites that make up the financial perspective for the period 2007-2013. Titles that make up the financial perspective are as follows: sustainable growth; preservation and management of natural resources; citizenship, freedom, security and Justice ; EU global partner administrative expenditure compensation. The basic rules for the system of own resources are legislated by the Council decision of 7 June 2007 adopted unanimously by the Council of the EU and ratified by all Member States. Total amount collected from its own resources needed to finance the Community budget is determined by the total level of expenditure. The maximum amount of own resources shall amount to 1.23% of EU GNI. Recent consultations on the reform of the budget showed that the stakeholders in the process are critical to the current arrangement of EU revenue.


Hereditary gingival fibromatosis, also known as congenital familial fibromatosis or idiopathic fibromatosis, is a rare genetic disorder with prevalence of 1/750000 [1,2]. This disorder may show as an isolated disease entity or as part of a syndrome [3,4]. As a single disease entity, it is typically transmitted as an autosomal dominant trait [5]. The main clinical features of hereditary gingival fibromatosis include severe generalized and progressive gingival overgrowth [6,7]. It can involve attachment gingiva, marginal gingiva and interdental gingival papilla, which always cover the teeth partially or completely. Gingiva are smooth, firm and usually normal in color. This disease usually appears during childhood and occasionally delays eruption of teeth [8,9]. The body and mental development of patients are normal [10]. The most important treatment for hereditary gingival fibromatosis is dental plaque control and elimination of gingival inflammation [11,12]. Gingivectomy is usually performed after adolescence [13].


Many fruits are rich in myo-inositol, a stereoisomer of the carbohydrate inositol. Myo-inositol is an intracellular second messenger that may act as an


Infant mortality rates in many developing countries have declined substantially during the past three decades, while neonatal mortality rates (i.e. death during the first 28 days of life) remain unacceptably high in many developing countries of the world. Neonatal mortality now accounts for approximately two-thirds of the 8 million annual deaths worldwide in children ,1 year of age and one-third of all deaths in children ,5 years of age. 2 For every early newborn death, another infant is stillborn, often because of infection; up to 80% of early preterm births are associated with an intrauterine infection that precedes rupture of membranes. 4 The first week of life is a particularly vulnerable period when 50 to 70% of fatal and lifethreatening illnesses occur. Worldwide 98% of all neonatal deaths occur in developing countries, mainly in Africa and Asia, and most are attributable to infection, asphyxia and low birth weight. An estimated 20% of all children born in developing countries, or 30 million annually, develop an infection during the neonatal period. Infections account for an estimated 30 to 40% of the neonatal deaths, caused principally by acute respiratory infections (; 750 000 deaths per year), neonatal tetanus (375 000), sepsis (300 000) and diarrhea (150 000). 3 As the regional mortality rate increases, infections are believed to cause an increasingly higher proportion of the deaths. Conditions that affect the neonate, including infections, impact not only neonatal mortality but also long term morbidity through effects on neurologic and cognitive development and associations with chronic diseases (e.g. diabetes, cardiovascular disease, chronic lung disease). This is particularly relevant to HIV-1 infection, wherein significant effects on health typically are lacking during the neonatal period but become profound later in life. Thus interventions that prevent acquisition of or morbidity from disease during the neonatal period have the potential to be highly cost-effective and impact the individual's health far beyond the neonatal period. Despite the public health significance, few programs target neonatal health in developing countries. Research to develop, test and adapt cost-effective, practical sustainable interventions to reduce neonatal morbidity and mortality in developing countries is needed, because development of effective strategies for improving neonatal health may now hold the greatest potential and promise for improving the survival and health of future generations of children. Given the vast scope of the need, however, intervention strategies and research efforts must be prioritized to utilize available resources for improving neonatal health most effectively. A large number of antenatal (Table 1) and intrapartum (Table 2) practices may impact acquisition and outcome of infectious diseases during the neonatal period. This report focuses on care of the neonate (i.e. postpartum strategies) and avenues of research most likely to effect a reduction in neonatal morbidity and mortality in developing country communities. Despite knowledge of the effectiveness of a number of interventions to reduce neonatal mortality, many newborns continue to die of preventable causes. Failure to identify and address socioeconomic barriers to seeking and receiving health care and failure to implement proven preventive measures contribute to these deaths. Strategies to reduce neonatal morbidity and mortality must be implemented within a sustainable health system that can improve the general health of women, provide accessible and acceptable antenatal Accepted for publication April 20, 2000. From the Department of International Health, School of Hygiene and Public Health, The Johns Hopkins Medical Institutions, Baltimore, MD (GLD, REB, MS); and the Departments of Pediatrics and Medicine, University of Washington School of Medicine, Seattle, WA (GLD). Presented as Postpartum Strategies for Reducing Neonatal Infections, Reducing Perinatal and Neonatal Mortality: Review of Potential Interventions and Implications for Programs and Research, May 11, 1999, School of Hygiene and Public Health, The Johns Hopkins Medical Institutions, Baltimore, MD.


In an industry facing major unsustainability issues, companies struggle to implement sustainable practices, to ensure the sustainability of their supply chains. Sustainable fashion supply chains are a source of competitive advantage if applying sustainable manufacturing, eco-material production, green distribution, green retailing and ethical consumer practices. We will analyze the action of two companies, Inditex, and H&M, companies recognized for the efforts they undertake in order to ensure the sustainability of their supply chains, businesses and brands.


The authors report surface charge retention and enhanced ferroelectric polarization effect on ferroelectric thin films by Kelvin probe force microscope (KFM). Since high electric field is induced at scanning probe microscope tip during domain switching and the sign of surface charge induced by this high electric field is always opposite to the sign of induced ferroelectric polarization charge, the surface potential of the KFM signal exhibits the relative potential difference between the potential of the ferroelectric polarization charge and the potential of the surface charge. After the discharge process of surface charge, the enhanced contribution from the ferroelectric polarization charge was observed. Similarly, the reduction of surface charge was observed as time passed and the surface potential indicating the ferroelectric polarization charge was enhanced due to this retention property of surface charge.


We report about a two year old girl with onset of severe temporo-parieto-occipital seizures at age of 7 month, retardation of speech development and ataxia. High resolution T2-weigthed MRI identified a hyperintense lesion arising from the ependyma of the right ventricle to the right superior temporal gyrus. In addition, T1-weighted MRI indicated a slightly hyperintense nodular area within this lesion as well as minute calcification. Neuroradiological inspection was highly compatible with a transmantle type of focal cortical dysplasia or cortical tuber (without further lesions of the tuberous sclerosis complex). PET revealed a hypometabolism of the right parieto-occipital lobe. Maximum valproic acid and oxcarbazepin medication were not sufficient to control seizure activity. Temporo-parietal resection of the lesion was performed and histopathologically examined. In contrast to the clinical diagnosis of a transmantle-type focal cortical dysplasia (FCD type IIB according to Palmini et al., 2004), microscopical inspection revealed a ganglioglioma presenting with dysplastic neurons, a neoplastic glial cell population and expression of CD34– immunoreactive satellite clusters (WHO grade I). Proliferation activity was in the range of 1%. Calcification was present and appeared as microscopically small deposits within small capillaries and neuropil. There were no hint for the presence of balloon cells. Seizure activity is controlled after surgery (postoperative time interval is only 4 month yet). Retrospective analysis of MRI data sets were performed, but gave no further hint for a neoplasia. This is an interesting lesion with histopathological hallmarks of a ganglioglioma (WHO grade I) mimicking a transmantle sign typically observed in FCD type IIB. Indeed, recent molecular-pathological studies point to similar signalling pathways operating in both lesions, i.e. the insulin-growth factor receptor cascade activating the tuberin/hamartin complex.


Spray columns and towers are fundamental in many industrial applications. Understanding the spray pattern in these dynamic environments is very important in the design of an overall spray system solution. Traditional laboratory physical experiments can be time-consuming, expensive, and sometimes impossible to complete. Computational fluid dynamics (CFD) modeling can be used effectively in this area. In this case study, a slurry feedstock is injected into a reaction column through numerous nozzles and a significant amount of the feed gets flashed quickly after exiting the nozzles. The gas from flashing produces a complicated flow field in the column that has a great impact on the spray pattern. A critical factor in the operating process is a requirement that the spray have good coverage over the column while not impinging on the sidewalls. CFD is the tool we used to optimize the position and the orientation of each nozzle in this spraying system. The gas flow field in the column is solved by the Navier-Stokes equations while trajectories of droplets are calculated by the discrete phase model (DPM). The flow field and the droplets' calculation are closely coupled, allowing the interactions of spray and flow field to be accurately captured. Droplet size distribution of the spray is closely accounted for as well. In this case study, different nozzle layouts are studied and compared for optimization of the nozzles and their respective placement. From the simulation, it is apparent that flow-spray interactions are vital in the prediction of spray pattern.


Aims: The aim of this consensus paper is to review the available evidence on the association between moderate alcohol use, health and disease and to provide a working document to the scientific and health professional communities. Data synthesis: In healthy adults and in the elderly, spontaneous consumption of alcoholic beverages within 30 g ethanol/d for men and 15 g/d for women is to be considered acceptable and do not deserve intervention by the primary care physician or the health professional in charge. Patients with increased risk for specific diseases, for example, women with familiar history of breast cancer, or subjects with familiar history of early cardiovascular disease, cardiovascular patients should discuss with their physician their drinking


The results of investigations dealing with the ability of Salmonella pullorum and Salmonella gallinarum to reduce nitrates to nitrites in a nitrate-peptone solution do not agree. Rettger and Harvey (1908) reported reduction by both organisms. Bushnell, Hinshaw and Payne (1926), Kaupp and Dearstyne (1927), Wallace and Neave (1927), and Tittsler (1928) reported reduction by Sal. pullorum. Hadley, Elkins and Caldwell (1918) found no reduction by either organism. Gage (1922), and Hadley, Caldwell, Elkins and Lambert (1917) reported no reduction by Sal. pullorum. Kaupp (1927) states that nitrates are reduced by Sal. gallinarum but not by Sal. pullorum. Bergey's Manual (1925) characterizes both organisms as negative to the nitrate test. Mallmann (1925) in an extensive study of Sal. pullorum found considerable variation. In 1924 his cultures gave a "weak positive test," but in 1925 some "were strongly positive, while others were weakly positive" and still others "were positive in only one tube." Perhaps the differences in results were due to differences in the media or methods of testingfor nitrites; however, no definite conclusions can be drawn since no statements were made concerning these points except in the reports of Wallace and Neave (1927) and Tittsler (1928). The assumption that a "Standard Nitrate-Peptone Solution" was used would be erroneous, as evidenced by the report of Conn and Breed (1919) which


Chain structured vibration systems with N degrees of freedom with masses mj and stiffnesses kj have been discussed in detail [1]. Some of them can be solved explicitly, others only numerically. Here, an inverse problem is considered: How mj, kj, j = 1, …, N, should be chosen such that the related eigenvalue/eigenvector-problem can be solved by Laguerre polynomials? (© 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim)


The practical use of cogeneration is as old as the generation ofelectricity itself. When electrification of broad areas was devised to re-place gas and kerosene lighting in residences and commercial facilitiesthe concept of central station power generation plants was born . Districtheating systems were popular during the late 1800's and why not. Dis-trict heating dates ba ck to Roman times when warm water wascirculated in open trenches to heat buildings and communal baths. Dis-trict electrification dates back to Thomas Edison's plants in New Yorkand it didn 't take long to combine the two . The prime mo vers that droveelectric generators thro w off waste heat that is normally blo wn to atmo-sphere. By capturing that heat and making low pressure steam thatsteam could be piped throughout the district for heating home s andbu sinesses. Thus, cogeneration on a fairly large scale was b orn .


Two fox species inhabit the Kaa Iya del Gran Chaco National Park in Bolivia: the crab eating fox Cerdocyon thous and the pampas fox Pseudalopex gymnocercus. We present the results of a study of the spatial ecology of these two species in Kaa Iya. In a series of bi-monthly systematic camera trap surveys, we set between 21 and 32 camera traps at different research camps over a four-year period (2001-2005). We recorded 215 photos of crab-eating foxes and 206 photos of pampas foxes. We captured three pampas foxes and four crab-eating foxes and fitted them with radio telemetry collars. Activity patterns of foxes (obtained from camera trap photos) were similar for both species: the activity peak was between 18:00 and 23:00h, with less activity between 10:00 and 17:00h. Home ranges of crab-eating foxes were between 155 and 293ha and for pampas foxes between 73 and 183ha. Female home ranges for both species were smaller than for males and only in one individual we observed a seasonal home range shift. Introduction The Gran Chaco is the third most extensive ecosystem in South America, covering more than one million km2. Canids are widely represented by two species, crab-eating fox and pampas fox, with the bush dog Speothos venaticus recently reported for the first time in the Kaa-Iya del Gran Chaco National Park, and the maned wolf Chrysocyon brachyurus in Copo National Park (Argentina). Even though both fox species inhabit a wide variety of Chaco habitats frequently in sympatry, the pampas fox is found more frequently in drier areas from southern Bolivia to central Argentina, while the crab-eating fox is more generalist, distributed in diverse environments below 2,000m (except Amazonia), and is scarce and even absent in the drier areas of Chaco (Eisenberg and Redford 1999, Emmons and Feer 1999). This paper compares home ranges and activity patterns of these two species in the Kaa-Iya National Park. Maffei et al. Sympatric foxes in Bolivia


Forests have significant function related biological diversity, habitat protection of flora fauna such as orangutan, tiger, elephant; climate-related functions such as carbon sequestration, air pollution; human settlements, human health, school activities, habitat for people, rural livelihoods; state defense as natural resources such as commercial industrial wood,  non-wood forest products, international and national trade; ecotourism, recreation. However the problem in Indonesia is forest fires. In order to maintain  its  functions, all the famers, forestry-concession owners, government, local government and private enterprise should prevent and suppress the forest fires through the existing law and regulations such as Constitution Law of 1945, Act Number 5 Year 1990, Act Number 22 Year 1999, Act Number 41 Year 1999, Act Number 1 Year 2009, Act Number 6 Year 1994 and Act Number 17 Year 2004 and aircraft operation conducted by foreign aircraft such as Australia, Canada, Malaysia, Russia and Singapore to assist Indonesian's forest fires. Keywords: aircraft operation; forest fires; legal ground; liability; responsibility


The Outline of the 11th Five-Year Plan for National Economic and Social Development sets forth the strategic target for comprehensively implementing the scientific development conception, building resource-saving and environment-friendly society. Based on the target, this paper introduces a thought on building resource-saving and environment-friendly green shipbuilding industry, and makes related suggestions how to build the green shipbuilding industry in the way of design, technology, management mode for the sake of discussing together.


Foliage stems of anthurium (Anthurium andraeanum L.) f. cv. Apalai were submitted to two experiments. In the first one, a pulsing solution with sucrose at concentrations of 0%, 2%, 4%, 6% and 8% were used, and in the second experiment, gibberellic acid sprays at concentrations of 0, 100, 200, 300 and 400 mg L-1, all experiments were kept at room temperature of 25 oC and relative humidity of 75%. Sucrose treatment was not effective nor in the color maintenance neither in the stems weight, but for the gibberellic acid the best treatment applied was 200 mg L-1 concentration that maintained the higher scores. Treatment with gibberellic acid enabled efficient storage for 22 days.


In the last part of the book, Hillis explores how gay men use webcams to engage with the paradoxes created by fetishism coupled with widespread homophobia. Why gay men? Both privileged as men and stigmatized as queer, gay men were early adaptors of a technology that allowed them to be, in their own minds, both public and private about their sexuality and have a modicum of control over their fetishization. He points out how economically difficult being an early adaptor (and, thus, early adapter) of webcams turns out to be. This was a serious, and often unsustainable, financial commitment as well as an aesthetic commitment on the part of these gay men. In addition, Hillis suggests that gay men have parts of their own ambivalent social status confirmed by the mechanics of virtual presence spatially. Virtually, as Hillis argues at numerous pointsinthebook,oneisalwaysbothonlineandembodied, virtual presence always involves a representational anchor elsewhere. Gay men face a similar situation temporally: denied full acknowledgment in the present moment, they orient toward a possible future of acceptance, of being fully acknowledged as present, always here and not here, now and not now. Lastly, gay men struggle with how their telefetish is always commodified. According to Hillis, in these instances, they are actively volunteering to be fetishized, which is both affirming and disquieting in equal measure. Hillis suggests that over time, this tension is unsustainable, and many gay men only volunteer to be fetishized for a certain period and then quit. Online a Lot of the Time asks significant philosophical questions about how our theoretical traditions are challenged by online communication. Ethnographers may prefer concrete examples in which the nuances of the material are carefully explored. This book points the way to some ethnographic places to begin answering these very EuroAmerican questions.


How to efficiently select Web services that can best meet the requirements of consumers is an ongoing research direction in Web service community.Through the transforming of the automatically clustered web WSDL documents into the functionally similar cluster of homogeneity,we can create a service search engine successfully and at the same time the search space can be reduced.By means of providing a technological means(services framework),The characteristics of a series of related web services can be automatically collected,found and integrated,then followed with a clustering method,we can put them all together into a group which can be found and applied.


A column leaching study was conducted in the laboratory to assess the leachate composition and heavy metal contamination of soils amended with coal fly ash. For this purpose, soils amended with two types of coal fly ash freshly precipitated dry fly ash (DFA) and lagooned fly ash (LFA) at levels ranging from 40 to 240 t ha -1 were used. There was a significant increase in the EC (total salts) of the leachate due to fly ash amendment. The EC increased from 0.62 dSm at control to 1.57 dSm with DFA application at 240 t ha -1 in Kathalagere soil. In DFA amended soils, there was a significant increase in leachate EC level at the beginning followed by a sharp decrease as the volume of leachate increased. This indicates that DFA has higher amount of readily soluble salts compared to LFA. The B content increased from 0.63 mg L at control to 1.60 mg L with DFA at 240 t ha . Significant increases in SO4 and Ca content of leachate were also observed in leachate collected from fly ash amended soil columns compared to control. The leachate was found to be highly saline (C3) and having B concentration higher than the prescribed safe limits. The heavy metal loads left on the fly ash amended soils at the end of the leaching period were significantly higher compared to unamended soils. The heavy metal loads recorded at 240 t ha -1 of DFA application were 267.6, 2.5, 68.1 and 87.7 mg kg of Cr, Cd, Ni and Pb respectively in Kathalagere soil.


It is a familiar feature of the tradition of moral philosophy which began with Socrates that its primary concern is with virtues and vices, with what it is to be a good man and why one should aspire to perfection of the soul. By contrast, the focus of much modern ethics is on actions rather than on character, the primary concern being with principles of right conduct.


A new BCD-192 chest refrigerator with the double-capillary tube in tandem refrigeration cycle has been designed and produced. According to the correlative requirement of the national standard, many experimental researches on the performances of the tandem double-capillary tube refrigeration cycle respectively adopting refrigerant R-12, R-134a and R-600a have been done detailedly. The experiment results show that in contrast to the energy consumptions of the BCD-192 chest refrigerator with the single-capillary refrigeration system, the energy consumptions of the BCD-192 chest refrigerator with the new refrigeration system decrease almost by 8, 7.5 and 8.3%, when refrigerant R-12, R-134a and R-600a are adopted respectively.


Pronunciation is an aspect that students in Indonesia should be known and und  erstanding how to express each word in English. To make students easier to produce something in English, the writers take English song as a media to improve students' pronunciation. Beside of they can learn how to produce something in English language; they can gain the language or a new vocabulary.  The research used pre experimental design with one group pre test and post test design which consists of 36 students as the sample. Then the data processed by SPSS 21. And the result of this research showed significance value was .00 and it is lower that the criteria .05. It means the null hypothesis was rejected and the alternative hypothesis was accepted that English song is influence media in improving students' pronunciation.


To the Editor: We read with interest "A review of the experience with pediatric written requests issued for oncology drug products."1 The authors emphasize that children typically do not have the same cancer types as adults. But post-pubescent minors are physiologically more mature than neonates. We agree that developing promising new drugs for children is critical to public health. Doubtlessy, the oncology written requests (WRs) reflected best intentions, but good intentions can result in poor outcomes.2,3 Cobimetinib, dabrafenib, and trametinib received WRs for melanoma. Their study data are listed as not yet completed.1 No pediatric studies triggered by theWRs for cobimetini, dabrafenib, or trametinib are listed onwww.clinicaltrials.gov andhopefully none will ever begin. Pediatric melanoma studies with ipilimumab and vemurafenibwere terminated.4,5 They offeredmonotherapywhen combination therapy had become standard of care. As a result, recruitment waned.6 Prepubertal malignant melanoma types exist. However, most minors with conventional malignant melanoma are adolescents and do not have "pediatric" melanoma.6,7 The WR for docetaxel triggered an international "pediatric" nasopharyngeal carcinoma (NPC) study in patients ≤21 years of age.8,9 NPC occurs also in minors, but is not a pediatric disease.10,11 The WRs for single cytotoxics were issued, although these were already successfully used in "cocktails."12 These WR-triggered studies had no therapeutic intention, contrary to those performed by the pediatric oncology networks.12 They aimed at "pediatric" labels.13,14 The FDA justified such studies by emphasizing that study participation had become standard of care.15 However, this is true only for reasonable studies.13,14,16 The term "child" has two meanings. Legally/administratively it describes minors, who bodily mature from conception over birth until maturation with puberty.14,17 Furthermore, puberty has accelerated.18,19 The pediatric warnings that moved Shirkey to characterize children as "therapeutic orphans" had the legal purpose to protect manusfacturers against frivolous lawsuits in the litigious United States.13,14,20 Their kernel of truth were toxicities in premature newborns observed in the 1950s.21 The "moral imperative" for "pediatric studies," expressed by the American Academy of Pediatrics,21 is based more on morality than on science. It is semantically a blur at the interface of medicine and law and is maintained by conflicts of interest. "Pediatric" studies became a business opportunity for pediatric researchers, industry, commercial clinical research, and have advanced careers in regulatory authorities, research, and industry.13,14,16 Not all cancers in minors are "pediatric." Pediatric oncology emergedwhen effective drugs already existed, took decades to reach today's successful results,12 and worked "off-label" decades before this term emerged in 1988.22 Today's innovative treatments engage the body's immune system. The youngest patient with acute lymphoblastic leukemia (ALL), the most frequent pediatric malignancy, was 6 years old when successfully treated after relapsing after chemotherapy.23–25 The FDA today recommends the inclusion of adolescents into adult cancer studies,26 while the EuropeanMedicines Agency (EMA) expands "pediatric" demands into diseases that occasionally occur before the 18th birthday, for example, hepatocellular carcinoma.27 It is time to acknowledge that many regulatory "pediatric" studies are pointless and often harm, withholding effective treatment.13,14,16 Institutional Review Boards/ ethics committees should reject questionable "pediatric" studies and suspend harmful ones. The FDA should re-consider questionable collaboration with the EMA in the "pediatric" cluster.28,29 Long-term, pediatric legislation needs revision.13,14,16


A new method for the synthesis of l-2',3'-dideoxyisonucleosides is described. The readily available, optically active C2-symmetric bis-epoxide (2S,4S)-1,2:4,5-diepoxypentane (5) was prepared by a short route from readily available starting materials. The key step of the new synthesis is the opening of 5 with nucleophiles, which proceeds highly regioselectively; e.g., reaction with sodium sulfide affords a 5:1 mixture of the tetrahydrothiophenediol 9a and the tetrahydrothiopyrandiol 14, and reaction with sodium hydroxide gives exclusively the tetrahydrofurandiol 9b via a preferred 5-exo cyclization. These five-membered diols 9a,b can be converted in only four steps into the modified dideoxyuridine and adenosine isonucleosides 4a−c, one of which (4c) has shown good antiviral activity. In addition, we have examined the opening of the analogous six-carbon bis-epoxide, (2S,5S)-1,2:5,6-diepoxyhexane (23), which affords a 3:1 mixture of the hexahydrothiepinediol 24 and the tetrahydrothiopyrandiol 25 with sodium ...


Objective:learing the status of lipid disorders in colleges.Methods: analyzed the data of lipid testing by taking those aged over 40(including 40 years) in a college this year.Results: The overall prevalence of dyslipidemia is 53.2%,high density lipoprotein cholesterol(LDL-C) 36.9%,high total cholesterol(CHOL) 30.2%,and high triglycerides(TRIG) 26.7%.Male high-density lipoprotein cholesterol(LDL-C) is(41.6%),obviously higher than female(29.8%).The indicators of dyslipidemia of women after the age of 50 is significantly higher.Conclusion: The dyslipidemia in older faculty is prevalent.Male high-density lipoprotein cholesterol(LDL-C) is significantly higher than female.Female the lipids after aged 50 increase obviously.The menopausal women should be careful to prevent cardiovascular disease.


Purpose To study the effects of peroxisome proliferator-activated receptors (PPARs) agonist on experimental atherogensis of rabbits. Methods Twenty-four New Zealand white rabbits were devided into 3 groups:8 were selected as ordinary diet group,8 as atherogenic diet group,the others as treatment group administered with atherogenic diet and rosiglitazone (2 mg/d).Serum lipids,tumor necrosis factor-alpha (TNF-α),interleukin-6 (IL-6),atherosclerotic plaque/intima size ratio of aorta and the number of infiltrating macrophage in plaques were examined on the 0,8th week. Results Rosiglitazone had no effect on the lipids compared with control groups,the level of circulating TNF-α,IL-6,plaque/intima size ratio and the number of infiltrating macrophage in the treatment group was significantly lower than those in control groups (all P0.001). Conclusions Peroxisome proliferator-activated receptors agonist rosiglitazone could prevent the atherogensis of rabbits.


This study was conducted to evaluate the factors influencing students' intention to use E-learning system. Seven dimensions in this study were determined are Computer self-efficacy, Computer experience, Enjoyment, System characteristics and Subjective norm, Perceived ease of use, and Perceived usefulness. In which, Computer self-efficacy, Computer experience, Enjoyment and System characteristics impact on Perceived usefulness of E-learning, while Computer self-efficacy, System characteristics and Subjective norm impact on Perceived ease of E-learning use. Perceived usefulness and Perceived ease of use impact on Intention to use E-learning. The research methodology was conducted in a survey with participation of 246 respondents from 20 universities. The data was analyzed by using descriptive statistics, factor analysis and regression. The empirical results showed that Computer self-efficacy has no impact on Perceived usefulness of E-learning, and System characteristics has no impact on Perceived ease of E-learning use. Finally, this study recommended some solutions, which universities thereby makes some recommendations to universities to attract more students in participating in E-learning until it is officially implemented for the universities' training systems.


A number of atmospherically important trace gases (dimethyl sulphide (DMS), methyl iodide (CH3I), and nonmethane hydrocarbons (NMHCs)) were measured simultaneously in the eastern Atlantic Ocean during May 1997. This investigation was part of the U.K. Atmospheric Chemistry Studies in the Oceanic Environment (ACSOE) Community Research Program and covered a 200 by 200 nautical mile (1 nautical mile is 1.852 km) area to the west of the Mace Head Atmospheric Research Station on the coast of Ireland. Different spatial and temporal patterns were observed for each of the gases, showing that distinct sources dominate their production in this region: specific species of phytoplankton (DMS), macroalgae (CH3I), total phytoplankton biomass (isoprene), and photochemistry (ethene). Sea‐to‐air fluxes of the gases are calculated for near and offshore domains, and their temporal variations are discussed. A simple photochemical box model has been used to assess the contributions of the gas fluxes to the levels of the gases observed at Mace Head. Results show that the area studied may constitute a substantial source of DMS, a weak source of CH3I, a small source of ethene at night, and an insignificant source of isoprene to atmospheric levels of these gases measured at Mace Head in western Ireland.


Underestimation of the proportion of women receiving at least 1 immunization for tetanus during pregnancy based on data taken from Phase I of the Demographic and Health Survey (DHS) is discussed for Ecuador (1987) Ghana (1988) and Sri Lanka (1987). Specifically the question is to what extent immunization rates for births in the past 5 years may underestimate tetanus coverage. Bias may be involved in life-long protection if there is a relationship between tetanus immunization and parity or maternal age or recall as measured by a negative relationship between immunization rates and the length of the open-birth internal or the duration since the last birth. Variations in infant mortality were 58 77 and 25/1000 live births for Ecuador Ghana and Sri Lanka respectively and tetanus immunization levels of 39 70 and 83/1000 live births respectively. Confounding factors of prenatal care mothers education or area of residence are controlled for. Women with no formal prenatal care were excluded from the sample where data were available (Ecuador and Ghana). The results of logistic regressions yielded no strong effect of parity or maternal age; hence there is no evidence of life-long protection bias. For last births there is no strong linear relationship between the length of the open interval and tetanus immunization; hence there is probably no recall bias. The probability of tetanus immunization for the birth is regressed or urban residence and mothers years of schooling controlling for formal prenatal care. The result was statistically insignificant except for possibly Ecuador. In Sri Lanka there is a strong significant and positive relationship between duration since last birth and immunization probability. The implications of the absence of the life-long protection bias are that all women may be vaccinated at each pregnancy regardless of their immunization history or the immunization program is new and weak in providing 5 doses of vaccine to a significant number of women. Over immunization is not considered a health risk. Recall bias was not found in Ghana or Sri Lanka. Sri Lankas recent lower immunization rates may reflect a weakening of the program. The results for Ecuador show nonlinearity and do not definitely confirm a recall bias. It is suggested that immunization histories be made available at the time of the survey thereby eliminating the need for estimation. Since underestimation bias was not found and overestimation is not measurable DHS measures of tetanus coverage may be a reliable estimate of full immunization.


The association virulence on the pathogen from gray mold disease of tomato was determined by measuring the inhibition rates of hypha on the agar meaia with different proportions of sumilex and thiram and by analyzing the Finney probability. According to the result, the proportion of two kinds of drug in the prescription was suggested.


Leptocybe invasa Fisher & La Salle was first recorded several years ago in Sri Lanka in the Eucalyptus camaldulensis Dehnh. plantation in Maragamuwa. Recent observations have revealed a decrease in gall infestation, and the present study was conducted to investigate the biology of L. invasa, its damage to E. camaldulensis and the presence of any natural enemies. Life-cycle duration, developmental stages and activity patterns were investigated. The abundance of gall wasps was monitored using sticky traps. Damage caused to different stages of coppices was also assessed. The damage index was calculated from the percentage of leaves affected in each coppice. Insects were reared from the galled coppices, brought to the laboratory, identified and counted. The life-cycle duration of L. invasa was 132 days on average. The damage index was low throughout the study period. Leptocybe invasa attacked the coppices of E. camaldulensis when they turned green in colour; damage increased as the coppices developed until maturity. Four species of parasitoid wasps were reared from the leaf and shoot galls. Megastigmus sp. was the most abundant parasitoid; the mean percentage of parasitization was 67.00 ± 8.00. Natural enemies of L. invasa might have contributed to the decrease in gall infestation observed recently in the coppices of E. camaldulensis in the study site.


Provides details of new developments in negligent training by researching articles in current trade magazines over the last six months. Gives details of employee related litigation that have recently been in the headlines and states any appropriate recommendations or preventative measures to help employers combat employee related litigation. Covers subjects including age, pay, and hiring methods. Concludes that employers must constantly monitor developments in the law to enable their policies to remain up to date and minimise risk.


Abstract
Objective: resistance training on women's body composition, as well as to verify women's body composition before and after the 4 weeks of resistance training program. Methods: A clinical trial study was conducted with 5 female participants over a 4-week period with a weekly frequency of 3 times a week, lasting 40 minutes per day, during a 1-month training period. A physical evaluation was performed before and after intervention. Results: Through the results it can be seen that women did not have a reduction of fat percentage by 4.05% between the pre and post intervention period. Participants 5 were able to complete the study. The results of this study in the general data of the sample had low significance in fat percentage. The results showed that the strength training applied decreased the percentage of body fat and the increase in lean mass causing an impact on body composition. Conclusion: It was concluded that the fat weight percentage decreased at the end of the physical evaluation, making it satisfactory, but had a significant reduction in the fat percentage. Regarding lean mass, the results showed no significant reduction, neither increase nor reduction in lean mass.

Keyword: women, body weight, resistance training


The iodometric determination of peroxides in certain edible oils by the use of standard L-ascorbic acid solution is reported. Calculation of Lea number by the proposed method and the previously recognised sodium thiosulphate method is also given.


A stochastic typhoon model with three properties of central pressure, moving direction and moving velocity is constructed by using B-spline functions and multi-variate autoregressive models. This stochastic typhoon model generates hourly data of typhoon location, central pressure, moving direction and velocity. Predictors against the rainfall intensity and the storm surge at Osaka are selected by using a stepwise regression analysis. About 2820 typhoons for 600 years are generated, and rainfall intensities and storm surges associated with the simulated typhoons are generated at Osaka. The concurrent characteristics of rainfall and storm surge; such as the frequency distribution of time lags, the spatial distributions of typhoon locations, when the peak rainfall intensities and the maximum storm surges occurred. At the same time the joint return periods of heavy rainfall intensities and large storm surges, are evaluated by using observed and simulated data.


This study seeks to examine the work hours of truck drivers and the factors influencing drivers' supply of labor to the freight transportation market. Recently, truck driver hours have been the object of regulatory scrutiny and regulation by the U.S. Department of Transportation, ostensibly for safety reasons. The new Hours of Service regulations are being blamed by some in the trucking industry for decreasing the amount of labor supplied by drivers by drivers entering other fields of employment. While drivers operate under this regulatory environment, the current study examines the other determinants of labor hours for truck drivers. These determinants are particularly relevant in light of projections of a shortage in the supply of truck drivers within the United States in the near future, and the associated costs and rates of driver turnover within the trucking industry. The nature of driver employment, either as an employee of a firm, or as an owner-operator, is also examined within the context of modern industrial organization theories of transaction costs and agency. ___________________________________________________ *The author wishes to acknowledge the assistance of Kristen Monaco at California State University – Long Beach in obtaining the data used in this study and to Dr. Duane Leigh and members of a graduate seminar in labor economics at Washington State University. Introduction A truism of the current market economy is the fact that practically all goods consumed or produced in the United States moved at some point by truck, either from its place of production to a center of manufacturing, or from a center of manufacturing to a final point of consumption. Integral to this process are the truck drivers who physically move these goods from place to place. In light of recent surveys (American Transportation Research Institute, 2005) indicating the importance of driver retention and driver shortages, examinations of the motivating factors in the labor supply are timely. This study seeks to examine the work hours of truck drivers and the factors influencing drivers' supply of labor to the transportation market. Recently, truck driver hours have been the object of regulatory scrutiny and regulation by the U.S. Department of Transportation, ostensibly for safety reasons. The new federal Hours of Service regulations are effectively decreasing the amount of labor supplied by drivers and exacerbating an already existing truck driver shortage (Guido, 2005). While drivers operate under this regulatory environment, the current study examines other possible determinants of labor hours for truck drivers. These determinants are particularly relevant in light of projections of truck driver shortages within the United States in the near future, and the associated costs and rates of driver turnover within the trucking industry. The nature of driver employment, either as an employee of a firm, or as an owneroperator, is also examined within the context of modern industrial organization theories of transaction costs and agency. Previous studies have documented declining wages for truck drivers over the last 25 to 30 years (Hirsch and MacPherson 1997) and those factors of deregulation and human capital contributing to this decline (Belman and Monaco 2001). The American Trucking Association iv in 1997, identified driver retention and driver shortages as significant issues facing the trucking industry since the period of deregulation circa 1980. This study also found that several factors are crucial in retaining drivers such as "higher pay, more regular and predictable hours, greater benefits, or better equipment and working conditions." Given these recent trends of declining wages and truck-driver shortages, this paper seeks to address several questions. First, what is the real wage rate of truck drivers in comparison to the actual number of hours worked? Do various performance incentive schemes affect a driver's willingness to work? Do compensation and benefit programs provide incentives to drivers to provide more labor? What demographic, or specific individual characteristics affect the labor supply decisions of truck drivers? To what extent do these conditions affect a driver's employment relation decisions? In order to answer these questions a unique data set based upon an extensive driver survey conducted by the University of Michigan, is used to construct a model of driver wages and labor supply. One factor that may influence labor supply decisions from the truck drivers' perspective is the nature of the employment type that the drivers operate under. As noted by Nickerson and Silverman (2003), modern industrial organization theories of transaction costs and agency posit that the owner-operator form of employment should dominate truck driving. Reasons for this are the nature of trucks as non-specific capital assets that are easily redeployed (Williamson, 1985; Klein, Crawford and Alchian, 1978). This general lack of asset specificity in trucking argues against vertical integration by trucking firms (Tirole, 1988). Also, agency theory posits that delivery performance is usually easily measured, but that vehicle condition and depreciation are less easily monitored by trucking firms and these costs should be internalized by the drivers (Milgrom and Roberts, 1992; Tirole, 1988; Williamson, et al, 1975; Alchian and Demsetz, 1972) through driver ownership of the trucks. Yet, in a 1991 study by the American Trucking Association, almost 70 percent of truck drivers were employees of firms that own the tractor rigs, assign the shipments to various drivers and manage the logistical functions associated with transporting goods from origin to destination. One explanation for this divergence between theory and reality is in the organizational market niche the trucking firm seeks to exploit (Scheraga, 2005). Using the University of Michigan Trucking Industry Program (UMTIP) survey data, a final question is asked. Given the labor supply variables noted above, the nonspecific nature of truck assets, and that the apparently "structureless" nature of the truck driver labor market (Williamson, et al, 1975), what is the probability that a driver will choose to be the employee of a trucking firm, or choose an owner-operator form of employment relation? Data and Models Standard models of labors supply (Borjas 1999) identify many of the variables associated with the hours-of-work decisions made by participants in the labor force. In addition to the hourly wage, demographic variables such as educational attainment, race, marital status and gender have all been shown to have an effect on labor supply. Other factors that may influence labor supply decisions are nonlabor income and other forms of labor-related income such as health insurance, pensions and deferred income from savings plans, and the award of bonuses or imposition of penalties. This study uses information drawn from a truck driver survey conducted by the University of Michigan Trucking Industry Program (UMTIP) in 1997. The survey is an extensive questionnaire of 573 individuals regarding many aspects of truck driver's working conditions and work lives (Belman, et al 1998). From this survey, 481 observations have been extracted in order to examine the hours-of-work decisions made by truck drivers in relation to factors such as hourly wage, payment schemes, the provision of benefits such as health insurance, pensions or deferred compensation programs, and the presence of bonuses or penalties related to service. Monaco and Willmert (2003) have also examined wages and hours using UMTIP data in comparison to Current Population Survey data from the U.S. Census Bureau. The current study also uses the UMTIP data to examine the factors influencing the employment relation decisions made by truck drivers. The survey also has the benefit of detailed demographic and employment characteristic information regarding the drivers. Information obtained from the UMTIP survey includes data on the drivers experience as a truck driver, union status, the type of employer, and whether the driver classifies their job as "over-the-road," i.e., long-haul trucking, or local pick-up and delivery. Demographic information includes race, gender, marital status, spousal employment, the number of children, total family income in 1996, and the educational attainment of the driver. Educational attainment is classified as less than high school, some high school, high school, vocational or technical school, some college, associate's degree and bachelor's or higher college


This article provides an analysis of the legal and public discourse concerning the ''right of privacy'' in the 1960s. During that period the legal community had ambivalent feelings about recognizin...


Comment on Knuepfer et al, page [4078][1]

Malaria parasites export virulence proteins through intermediate protein complexes and membranous clefts in the host erythrocyte cytoplasm. GFP fusion proteins carrying the necessary export motifs provide new ways to study this phenomenon.

Plasmodium


The utilization is discussed of the GPSPAC, which is presently being developed to be used on the low altitude host vehicle (LAHV), for possible use in the shuttle avionics system to evaluate shuttle/GPS navigation performance. Analysis and tradeoffs of the shuttle/GPS link, shuttle signal interface requirements, oscillator tradeoffs and GPSPAC mechanical modifications for shuttle are included. Only the on-orbit utilization of GPSPAC for the shuttle is discussed. Other phases are briefly touched upon. Recommendations are provided for using the present GPSPAC and the changes required to perform shuttle on-orbit navigation.


Soybean is an efficient source of vegetable protein. National soybean production continues to decline during 2010-2012. The lowproductivity of soybean is one of them caused by drought stress. Therefore, it is necessary to use cultivation techniques which can improve the efficiency of water use, ie with deficit irrigation. Deficit irrigation can be evaluated by calculating the amount of crop water productivity. The purpose of the research is to calculate andcompare themagnitude of cropwater productivity andgrowth of three varieties of soybeanplants in each treatment evapotranspiration deficit. Researchwas conducted in September 2014 -December 2014 in the greenhouse of IntegratedField Laboratory and LaboratoryofWaterResourcesand LandDepartment ofAgriculture, University of Lampung.The experimentwas conducted using a factorial in completely randomized design (CRD) with two factors that is soybean varieties which consists of three varieties: Kaba, Tanggamus, and Willis and deficit ETC which consists of three levels: 1.0 x ETC, 0.8 x ETC, and 0.6 x ETC. Data were analyzed with Analysis Of Variance (Test F), then continued by LSD test at the significance level of 5% and 1%. Results showed that: (1) based on the total leaf area, Kaba and Wilis varieties of soybean plants have started stress at week 2nd in the treatment ET2 (0,8 x ETC), varieties Tanggamus began stress on the 3rd week of the treatment ET3 (0,6 x ETC). Eventually based on the production of soybeans plant, varieties Tanggamus andKaba remains stress in treatment ET2 (0,8 x ETC) except varietiesWillis on ET3 (0.6 x ETC), (2) the crop water productivity was not significantly different between treatments except treatment Tanggamus varieties ET3 deficit (0, 6 x ETC), (3) Kaba varieties have the highest production in the amount of 20.22 grams,while the cropwater productivity of the highest of the Wilis varieties is equal to 0.5 kg/m3. Keywords: evapotranspiration, deficit irrigation, soybeans


Constructionist-cognitive theorists hold that knowledge acquisition results from active construction by the cog- nitive subject.This article takes a discussion on fundamental issues of vocational English teaching reform with a constructionist and cognitive view,and tries to point out the key to successful reform is to establish a student-centered teaching model with outdated teaching concepts discarded,modem knowledge view reconstructed as well as quality-oriented education upheld.


1. INTRODUCTION Students learn by doing, not by listening. Physicists and chemists have long understood this, which is why students in these fields are required to perform experiments in the laboratory and write up their findings. Computer scientists also realize this basic truth, so many courses require the students to do some programming. For courses like Introduction to Pascal and Data Structures 101 it is not hard to dream up suitable exercises. For courses on operating systems, it is much more difficult to arrange for a suitable programming laboratory. This paper discusses a solution to the problem based on using a UNIX clone written by the author and available in source form for classroom use. The essential problem with operating systems is that even the small and simple ones are large and complex. The large and complex ones are unspeakable. It is simply not feasible to ask the students to write an operating system, no matter how simple, as an exercise for a one semester course. No one would pass. At the other end of the spectrum, the students can be asked to write a tiny piece of an operating system, such as a CPU scheduler, all by itself. This strategy has the advantage that everybody passes. Unfortunately, nobody learns anything about operating systems this way. The books and lecture material for most courses are already heavily skewed toward the few topics that can be pulled out of context and isolated, such as monitors, schedulers, and deadlock algorithms. Building the laboratory around these topics as well just makes things worse. The only reasonable approach is to distribute to the students a working, well-documented operating system that they can study in detail and then modify. In this way they get to see a whole system close up, without having to write all the code. This strategy is clearly attractive but it has three basic problems: • hardware • software • documentation Let us deal with these one at a time. Operating systems generally have to run on the bare machine. For a course in which the only computing facility available is a large time-shared computer ~or, heaven forbid, a batch system), there are obvious problems. Fortunately, substantial microcomputers have now become so inexpensive that acquiring 20 machines just for the operating systems lab is becoming a real possibility at many schools. There are IBM PC and even 20


In this paper we derive the new contributions to the effective Hamiltonian governs $\vert\Delta S \vert=1$ semileptonic tau decays in the framework of two Higgs doublet model with generic Yukawa structure. We list all operators, in the effective Hamiltonian, generated from the charged Higgs exchange up to one loop-level and provide analytical expression for their corresponding Wilson coefficients. Moreover, we analyze the role of the different contributions, originating from the scalar, vecor and tensor hadronic currents, in generating direct CP asymmetry in the decay rate of $\tau^-\to K^-\pi^0\nu_\tau$. We show that non vanishing direct CP asymmetry in the decay rate of $\tau^-\to K^-\pi^0\nu_\tau$ can be generated due to the presence of both, the weak phase in the Wilson coefficient corresponding to the tensor operator and the strong phase difference resulting from the interference between the form factors expressing the matrix elements of the vector and tensor hadronic currents. After taking into account all relevant constraints, we find that the generated CP asymmetry can be enhanced $6$ orders of magnitude larger than the standard model prediction.


Currently the healthcare industry undergoes disruptive changes so that the design of medical products requires much better speed, flexibility and inter-connectivity. Research and development of mobile health products require an intensive collaboration from cross-disciplinary teams. In order to succeed, healthcare product providers should adapt their engineering processes to the fast improving environment. This paper introduces a hybrid Lean-Agile approach for the medical wearable device development process with respect to the learning outcomes and quality management system.


The objective of the present review was to update the understanding of the types of liver abscesses, namely: pyogenic, amoebic and fungal and relate this pathology with verminosis, in general. Liver abscesses remain a challenge in clinical medicine throughout the world, whether in its diagnosis and or even in its therapy. In "short" it is a serious disease that affects 8-22 individuals per group of 100,000 inhabitants. In recent decades, there have occurred changes in epidemiology, advances in diagnostics and the emergence of new therapeutic alternatives; however some causes for such pathology are still common. Medical literature discusses that parasitism is still a common cause and salutary in the understanding of liver abscess. However, in recent literature it's been evidenced that the presence of gastrointestinal helminth parasites in preschool aged children has a direct relationship with pyogenic liver abscess. It's concluded that the pyogenic liver abscess is the most common type and has verminosis as one of its main causes.


Abstract This study aimed to investigate the accuracy of the artificial neural network in estimating thermal conductivity (k) of ferrofluid-based nanofluids. The parameters of and have been measured at 20–60 0.05, 0.1, and 0.2 vol.% and the results showed that was greater than by 89%, which is obtained at 60 and 0.2 vol.%. To estimate a three-layer ANN was developed that contained two, three, and one neurons, respectively. This neural network was able to estimate with less than 0.8% error considering of The response surface methodology was also implemented, and it was observed that cubic polynomials, taking to account of will figure out the best results so that can be predicted with an error of less than 0.5%.


The model developed in this paper explains the last-resort borrowing, deposit rate and portfolio decisions of dealers in the official short-term money market. Equations based on the model have been estimated from monthly data and they provide a very good explanation of the variables which are the subject of the study. They indicate that the last-resort rate has a significant influence on the rates paid on deposits with the dealers. Some equations explaining the supply of funds to the dealers have also been estimated. An important implication of these equations is that trading banks hold these deposits as a liquidity reserve against drawings on overdraft accounts. The policy implications of the results are discussed in the final section of the paper.


Hypervisors are complex software which may require the reimplementation of legacy stacks. On Microsoft Hyper-V virtual machines (generation 1), some devices are emulated in the userland of its root partition. To explore this attack surface, a specifically crafted open source toolchain called Hyntrospect has been developed. It aims at helping find vulnerabilities in a pragmatic way: by taking benefits of existing Hyper-V and Windows capabilities and tools to perform coverage-guided fuzzing on Hyper-V closed-source binaries. That approach was inspired by previous experiences with libFuzzer, a publication by Microsoft on their fuzzing campaign, and other research conducted on the topic. The specificity of that tool is to rely on debugging and as a consequence to run in a real environment. It was also written in the perspective of putting together techniques that could be ported in the future to other Hyper-V root partition's userland targets. After covering Hyper-V and the state of the art on its instrumentation and research, this paper introduces Hyntrospect and its associated design choices, and finally describes the outcome of the first runs and future endeavors.


Leadership humor is a new type of leadership that integrates humorous behavior into leadership. It is characterized by breaking the traditional dogmatic management and aims to adopt humorous and interesting interactive ways to manage and stimulate the benign behaviors of subordinates. Although the research on leadership humor has made some progress in both theoretical and empirical aspects, the research on the duality of leadership humor is still in its infancy. Through literature review, this paper analyzes the connotation of the duality measure of leader humor and the effect of different types of leader humor, and makes an in-depth review on the duality path and boundary conditions of leader humor influencing subordinates' behavior. Finally, in view of the difficulties and shortcomings of the research on leadership humor duality, four feasible research directions are proposed in the future.