Results of a series of seven long-term NPKMg fertilizer trials in different Sumatran sites showed variations in oil palm (Elaeis guiineensis Jacq.) responses to fertilisers. Identification of important site factors and quantification of their contribution on the response variations is studied. The information is essential to improve the current fertilizer recommendation system used for larger area of commercial fields with similar characteristics. Soil type, mineralogy and topography, and rainfall were possible factors that generated the variation. Soil retention and losses of the applied fertilisers by water mechanisms were studied in additional trials. The trials included comparisons of soil nutrients from added and zero K and Mg plots, runoff and leaching at sites with different rainfall and slopes, and a pot observation. Of the fertilisers applied the soils retained 9-41% K and 73-102% Mg. The effect of rainfall was greater than soil on nutrient loss. P. Rambong with double rainfall than Bah Lias received six and eight times greater loads of leaching and runoff, respectively. Consequently lost K and Mg by runoff on the same flat topography were respectively 1% and 2% at Bah Lias, and 18% and 10% at P. Rambong. Deep drainage removed the applied K and Mg by 2% and 5% at Bah Lias, and 15% and 23% at P. Rambong. The effect of land steepness exacerbated runoff losses of K and Mg to 28% and 13% at the higher rainfall site. Some possible measures to implement in the field included improved fertilizer application policy, and soil and water conservation.


A model recently proposed by Hacyan for primordial black hole (PBH) growth in the early universe is extended to a class of equations of state p=a/sub s//sup 2/epsilon (p = pressure, a/sub s//sup 2/ = constant sound speed epsilon=energy density) and to arbitrary time delay between the births of the universe and of the PBH. We show that the PBH mass grows asymptotically in proportion to the horizon mass of the background for all a/sub s/, and that the general-relativistic matching to a flat background demands that the ingoing Vaidya metric used to model the PBH be self-similar. We emphasize that this model is not in conflict with earlier work (Bicknell and Henriksen) that found no self-similar growth for a/sub s//sup 2/<1 because decompressive transitions were explicitly excluded there. Although formally correct for all a/sub s//sup 2/, we argue on physical grounds that only when a/sub s//sup 2/=1 is the present model liable to be realized.


We address the design of cognitive MAC protocols for opportunistic spectrum access in the presence of sensing error. Decentralized protocols are presented for ad hoc networks where there is no central coordinator or dedicated communication/control channel. Secondary users search for and access spectrum opportunities independently without exchanging local information on spectrum availability. We assume on-demand partial spectrum monitoring subject to sensing errors. Specifically, a secondary user may not be able to simultaneously sense the whole spectrum of interest due to hardware limitation and may only monitor the spectrum when it has data to transmit in order to conserve energy. We propose two approaches to formulating opportunistic spectrum access in the presence of sensing error by considering either a constraint on the probability of colliding with primary users or a penalty imposed on each collision. Under these formulations, we address the joint design of both the spectrum sensor at the physical layer and the cognitive protocol at the MAC layer to maximize spectrum efficiency while limiting the interference to primary users.


Decentralized network research has received substantial attention internationally, resulting in significant innovations in distributed databases, storage, and computing in the areas of cloud, fog, and edge computing. When it comes to decentralized networks, they are widely recognized "a network from the future" that possesses serious limitations in terms of trust and security. In a traditional distributed network, resources (i.e., computing power)are typically concentrated on a single server, or through a core server to "direct". Thus, a core server represents the upper limit of the capacity of the entire service, and it is susceptible to concurrency bottlenecks or excessive loads. Therefore, in a decentralized network, the absence of a core not only means that the load capacity of the entire network has increased significantly, but also that the entire network is more "open", the disaster tolerance is stronger, and the response time performance is faster. In this paper, a simple implementation of file sharing is presented, the feasibility of file sharing in a decentralized network is discussed, and its advantages and disadvantages are studied.


As a famous historian and philosopher of science,Donna Haraway criticized traditional view of scientific objectivity,feminist empiricism and feminist standpoint theory and offered situated knowledge or embodied objectivity as an alternative. Analyzing her works on this special issue,this paper concludes that the basic connotation of her opinions on scientific objectivity includes: invoking and reforming vision metaphor as a starting point,and emphasizing the epistemological significance of self- division /conflict of the subject,priority of partial perspective,object as an actor in knowledge production,and local nature of knowledge. It has a distinct tendency of postmodern feminism and provides important clues for scientific epistemology and the development of the feminist theory,and meanwhile there are still some problems to be resolved.


Background: Around 13 percent of families with newborns in Germany are in need of support from the early prevention networks. Cooperation Martina Schlüter-Cruse between the professionals working in healthcare and social welfare is Friederike zu Sayn-Wittgenstein essential for improving children's development opportunities. Freelance midwives are respected partners in the early prevention networks but there has been very little research on their view of this cooperation. Aim: The study analyses key behavioral concepts of midwives in the context of interprofessional cooperation and early prevention. 1 Osnabrueck University of Applied Sciences, Faculty of Method: The qualitative study is based on 27 problem-centered interviews with freelance midwives in Germany. Access to the field was Business Management and Social Sciences, Osnabrueck, Germany gained through posts on local mailing lists, adverts in professional midwifery journals, participation in conventions and by involving profes2 Witten/Herdecke University, Faculty of Health, Witten, Germany sionals acting as gatekeepers. The interviews were conducted based on a script, were digitally voice recorded and lastly transcribed. Data evaluation was carried out using a qualitative text analysis. Results: Establishing a relationship of trust betweenmidwives and their clients was identified as the focal point for midwives' cooperation in early prevention networks. This relationship shapes the working relations between midwives and clients as well as between midwives and child and youth welfare professionals. Some midwives build on the women's trust in order to refer them to services provided by the Youth Welfare Office, others use it to set themselves apart from the latter. Conclusion: The key challenge of freelance midwives is to carve out their role as a cooperation partner within the networks of early prevention without undermining the trust of their clients. This requires a clear and comprehensible framework for all actors involved in these networks.


Bulk-grown CdZnTe (Zn = 3%) substrates are the natural choice for HgCdTe epitaxy since it is lattice matched to long wave LW-HgCdTe alloy. However, lack of large area CdZnTe substrates, high production costs, and more importantly, the difference in thermal expansion coefficients between CdZnTe and silicon Read out Integrated Circuits (ROIC) are some of the inherent drawbacks of CdZnTe substrates. Consequently, Hg1-xCdxTe detectors fabricated on silicon substrates are an attractive alternative. Recent developments in the molecular beam epitaxy (MBE) buffer layer growth technology on Si substrates has revolutionized the HgCdTe research and offered a new dimension to HgCdTe-based IR technology. Si substrates provide advantages in terms of relatively large area (3 to 6-inch diameter is easily obtained) compared to CZT substrate materials, durability during processing, and reliability to thermal cycling. Innovations in Si-based composite substrates made it possible to fabricate very large-format IR arrays that offer higher resolution, low-cost arrays and more dies per wafer. Between Si substrates and HgCdTe has large lattice mismatch of 19%. This leads to dislocation densities of low-107 cm-2 for optimal growth of HgCdTe on silicon-based substrates as compared to the mid-104 cm-2 dislocation density of HgCdTe grown on CdZnTe. This paper present dislocation reduction by two orders of magnitude using thermal cycle anneal under Hg environment on HgCdTe grown on Si substrates and as well as defect reduction in Cd(Se)Te buffer layers grown on Si Substrates.


The solubilization and extraction of phenanthrene from loess soil by a bio-surfactant saponin were investigated with comparing of two conventional nonionic surfactant TritonX-100 and Brij35.The result showed that saponin had the ability of solubilization for phenanthrene with higher solubilization ratio(SR) and the micelle-phase/aqueous phase partition coefficient(Kmc) than those of TritonX-100 and Brij35 in both of aqueous solution and water/soil system.There was a linearly proportional relationship between the consolidation of saponin and the apparent solubility of phenanthrene in aqueous solution.The result provided a reference to the use of saponin for remediation of contaminated soils in engineered surfactant-enhanced washing.


Research indicates that university students present higher levels of psychological distress compared with non-student age-matched youth. These levels are higher among healthcare students, and even higher during the Covid-19 pandemic. Therefore, cost-effective large-scale interventions are needed in order to prevent further development of psychological distress during this period, and more generally. The aim of the current study was to assess the effectiveness of an 8-week Internet-based positive psychology intervention for healthcare students in Tunisia. A two-armed randomized controlled trial was conducted among a sample of 366 health care students (183 in the experimental group and 183 in the control group), with a majority of women (94%). The average age was 20.74 years (±1.64). The participants completed the following online questionnaires at three time-points (before the program, immediately after, and three months later): stress, anxiety, depression, emotional regulation, optimism, hope, study engagement, and well-being. Repeated-measures ANOVAs revealed significant positive effects of the intervention on all the measured variables for the experimental group. The results showed a significant improvement immediately after the intervention compared to the control group, which was maintained three months later. This program may thus be considered as a promising means of improving students' mental health and study engagement.


An analog-to-digital converter (ADC) for monitoring the voltages of a stack of eight Li-ion batteries is presented. The converted voltage range for each battery is 3–4.2 V with a maximum nominal input voltage of 33.6 V. High-voltage (HV) switches and a single HV capacitor make up the HV track and hold. The remaining part of the circuit operates at a nominal 5-V supply. An interleaved extended-range ADC makes up the architecture. It converts the eight channels in 720 <inline-formula><tex-math notation="LaTeX">$\mu\text{s}$</tex-math></inline-formula>. The battery monitor has been fabricated in a 0.35-<inline-formula><tex-math notation="LaTeX">$\mu\text{m}$</tex-math></inline-formula> triple-well 5-V HV CMOS process with drain-extended MOS HV devices. The prototype active area is <inline-formula><tex-math notation="LaTeX">$1300\times 650\ \mu\text{m}^{2}$</tex-math></inline-formula>, and the measured total power consumption is 3.64 mW. The measured input-referred noise is 177.9 <inline-formula><tex-math notation="LaTeX">$\mu\text{V}$</tex-math></inline-formula>, and the residual offset is 642.5 <inline-formula><tex-math notation="LaTeX">$\mu\text{V}$</tex-math></inline-formula>.


Noncompliant behavior of patients frequently interferes with effectiveness of treatment for a variety of medical conditions and can have serious consequences. Most clinicians have had little training in identifying the common causes of patients' noncompliant behavior, and clinicians have few tools to cope with this type of behavior. The goals of this article are to define noncompliant behavior, to discuss the most common reasons for non-compliance, and to provide new insight into noncompliant behavior that clinicians can use to design more effective strategies for coping with noncompliant patients.


PrefaceAcknowledgmentsOverview and Theoretical PerspectivesSocial Work Practice in the Twenty-first CenturyTheories of AgingIntegrated Gerontological PracticeStages in Gerontological PracticePsychological Problems and InterventionsAnxiety Reactions Among Older PeopleDepression Among Older PeopleSuicide Among Older PeopleSubstance Abuse Among Older PeopleDementiaSocial Psychological Problems and InterventionsSocial Workers and Aging FamiliesSocial Work Practice and End-of-Life CareBereavement in Later LifeWork and RetirementSociopolitical IssuesEconomic Policies and AgingPoverty and AgingHealth Policies and AgingImproving the Quality of Life: Social Services and AgingReferencesSubject IndexName Index


759Background: Microsatellite instability (MSI) has been associated with improved survival outcomes in early stage CRC. In stage IV disease, MSI represents only 3-5% of cases and currently the prognostic implications are less clear. There is however evolving evidence that treatment pathways should include anti-PD-1 antibodies given the encouraging results in heavily pre-treated MSI mCRC patients. We undertook an analysis of the South Australian mCRC population based registry to explore the relevance of MSI status in this population based registry. Methods: The registry was analysed to assess patient characteristics and survival outcomes comparing patients with MSI or microsatellite stable (MSS) disease. K-M survival analysis was used to assess OS. Results: 4359 patients are registered on the data base. 598 (14%) patients had been tested for MSI. 62 (10.1%) of these patients had demonstrable MSI. Patient characteristics and outcomes are summarized in the table. There are statistically higher rates of right...


Let R be a nonempty set, let N consist of all non-negative rational integers, and denote by RN the set of all functions on N to R. If R is a ring, a map M: R"—>P^ is linear if M(rxfx+r2f2)=rx(Mfx) +r2(Mf2) for rx, r2 in R, fx, f2 in RN. For a finite commutative ring with unit we determine which linear transformations M: RN—+RN can be realized by finite automata. More precisely, let A, B he finite nonempty sets. A map M: AN—>BN is an automaton transformation if there exists a finite set Q, maps Mq: A X£>—><2, Mb: A XQ-*B, elements h in B, q in Q such that corresponding to each/ in AN there exists an h in QN satisfying


Abstract In this work, a dynamic model was developed to simulate the transient behaviour of a pilot scale, continuous, siagewise, 15 plate distillation column separating a mixture of ethanol, iso-propanol and isobutanol. The accuracy of the predictions was assessed by transient response data collected during experiments under step changes in reflux ratio, feed flow rate and feed composition. Results demonstrated the feasibility of simulating multicomponent distillation under unsteady state conditions with fairly good success. Further improvements were suggested for a better accuracy


This thesis explores the experiences of women who have chosen to participate in amateur
football (known in Australia as soccer). It investigates and interprets effects of individual
experiences and perceptions of sport for women amateur football players on their
identities.
The present research proposes that women's exposure to sporting experience as players
has an influence on their identities both within and outside the sporting arena. The
arguments for this position are explored using local narrative which details the nature of
women's experiences of sports and their ever-changing identities. To understand these
experiences it is important to locate them within a foundation of historical context which
traces the history of football, the involvement of women in sports, the development of
women's football in significant countries and the journey of the game of women's football in
Australia. With this information about the historical journey of women's sport and football it
is simpler to examine the current effect of the sport on identity.
Theories of identity, gender and sports are analysed. The theoretical perspective taken in
this thesis builds on feminist ideologies and an interactionist approach to understanding
women and their experiences. Analysis is undertaken using sport as a site of self-discovery
and identity building best understood through investigation of women's individual
experiences.
This thesis uses qualitative research with in-depth interviews, participant observation and
reflexivity to investigate the research proposition. Interviews with thirteen amateur women
football players were undertaken to investigate their thoughts, feelings and perceptions,
and consequently information was collected about sporting experiences, perceptions and
effects on identity. This was combined with participant observation to assist in giving
context and clarity to the exploration. Finally, reflexivity was engaged to provide an added
measure of triangulation to the study.
The thesis analyses the data as it relates to the experiences of identity change and
transference between the identity domains of leisure, work and family. The findings
demonstrate that the experience of sports participation as a player provides women with
access to testing their established identities, practising additional identity traits in a
challenging and often new environment and, once having done so, transferring aspects of
their new-found identities to other areas of their lives. It found that sports participation
clearly influences the development, shaping and sustaining of identity for women in a
range of identity domains.
The findings demonstrated that the act of playing football brings with it a broad range of
impacts upon each woman's identity. Often the women expressed their appreciation of the
opportunity to practise and apply the self-awareness, connections, sense of team,
confidence, capability, aggression, sense of agency and fun they had adopted in the
sporting arena to other areas of their…


In our work we have reconsidered the old problem of diffusion at the boundary of an ultrametric tree from a 'number theoretic' point of view. Namely, we use the modular functions (in particular, the Dedekind η-function) to construct the 'continuous' analogue of the Cayley tree isometrically embedded in the Poincare upper half-plane. Later we work with this continuous Cayley tree as with a standard function of a complex variable. In the framework of our approach, the results of Ogielsky and Stein on dynamics in ultrametric spaces are reproduced semi-analytically or semi-numerically. The speculation on the new 'geometrical' interpretation of replica n → 0 limit is proposed.


The increased usage of online social networks in recent days attracts the attention of researchers. That makes analysis of social networks a significant concern. Link prediction is one of the problem of social networks, where links are predicted between users by analyzing the relationships between the nodes. As the size and usability of the social network grows, the accurate prediction of connections with limited public information is a challenge. This article introduces a novel approach for predicting missing links using a nature‐inspired method, the gravitational search algorithm. We selected seven real‐world networks and five widely used algorithms and also considered the sparsity of networks for the experimental evaluation of the proposed approach. The proposed GSA‐driven algorithm has shown a better or comparable AUC result than the other standard algorithms on these networks.


The methodology for experimental studies and the analysis of the obtained results intended to determine the analytical dependencies and numerical values of the coefficients in a mathematical model of the contact interaction of working body of digging machine with a frozen soil are presented. Modeling of the process was aimed to take into account the physical and mechanical properties of the frozen soils and to determine a nonlinear behavior of the stress distribution over the contact surface of working body. As a result of the research, the main principles of the processes were revealed, which allowed one to validate both the design parameters of the working bodies and the technological parameters of the frozen soil excavation by digging


TitleRelativistic Calculations of Shakeup and Shakeoff Probabilitiesas the Result of 1s-Shell Vacancy ProductionAuthor(s) Mukoyama, Takeshi; Ito, YoshiakiCitationBulletin of the Institute for Chemical Research, KyotoUniversity (1994), 71(4-6): 398-405Issue Date 1994-02-25URL http://hdl.handle.net/2433/77542RightType Departmental Bulletin PaperTextversion publisher


Recently, the authority for electricity regulations in Oman introduced a new regulation for grid-connected photovoltaic (PV) systems. One of the main concerns is how the penetration of the grid-connected PV systems would affect the Mazoon Electricity Company's (MZEC) load behavior, especially at peak times. This paper presents the behavior of grid-connected loads considering the MZEC, which is one of the power distribution companies in Oman. The Al Bashir primary substation load distribution network was used as a case study. The MZEC peak load pattern was considered with respect to solar PV connection regulations in Oman. Furthermore, the various timings for electricity billing and the expected incentives were also used in evaluating the economical benefits of integrating the solar PV systems into the power grid. Data were collected for two years for the feeder and distribution transformers in the power grid. The export and import average power generation within the period of the study were also investigated. The behavior of the grid loads was investigated before and after installing the PV systems. The variables of the average power, load import, and export for different periods were used to evaluate the system performance. The obtained results reflect that with proper synchronization of the solar PV systems in the power grid, the maximum load of the primary substation decreased from 80% to 40%, considerably saving cost. Consequently, more consumers could be fed with the excess solar power, with less distribution transformers in the power grid.


In this paper,the problem how to associate multiple target groups will be brought forward,by deficient remote sensing measurements from satellites.But it makes trouble for the reality of association by attribute that the target groups alter their kinematic states irregularly and that the accurate attribute of the target groups isn't easily required.In term of the knowledge that the terrain limits the target groups' movenment,this paper brings forward a multitarget association algorithm based on analysis of terrain grids.


Two field experiments were designed in a stripplot with four replications were conducted in the Farm of Tag El-Ezz Research Station (latitude of 30.56 N and longitude of 31.35 E), Dakahlia Governorate during 2012/2013 and 2013/2014 seasons to study the effect of four plant spatial distributions and irrigation intervals on yield and quality of sugar beet preceded by rice crop. The present work included twelve treatments represent the combinations between four plant distribution patterns (D1: planting on one side of ridges of 50-cm, D2: planting on both sides of ridges of 50-cm width, D3: planting on both sides of beds of 100-cm width and D4: planting three rows on beds of 150-cm width, with hill spacing of 20 cm in case of D1 and D3 and D4 as well as 40 cm in case of D2) and three irrigation intervals [irrigation every 25 days (R1), 35 days (R2) and 45 days (R1)]. The obtained results revealed that plant distribution patterns significantly influenced every studied traits in both seasons, except purity % in the 1 season. The highest values of all studied characters resulted from D3, while the maximum percentages of TSS, sucrose and purity resulted from D1 in both seasons. Applying D3 increased root yield by 21.7, 11.5 and 6.2 % t/fad in the 1 st season, corresponding to 18.2, 10.4 and 4.2% t/fad in the 2 one as compared with D1, D2 and D4, respectively. Irrigation intervals had a significant effect on all studied characters except purity% in both seasons. The highest values of all studied characters produced from R2 treatment, while the highest values of TSS%, sucrose% and purity% were recorded by R1. Applying R2 increased root yield by 3.9 and 8.2% t/fad in the 1 st season and 4.9 and 9.3% t/fad in the 2 one compared with R1 and R3, respectively. Planting on two sides of beds of 100-cm width and 20 cm between hills and irrigation every 35-days recorded the highest productivity and quality of sugar beet under the environmental conditions of North Delta.


Assessment of executive function in young children is amongst the most commonly used cognitive assessments; however, there is a paucity of childhood executive function assessment methods which can be used remotely. Here, we present a novel adaptation of two child-friendly variants of the Stroop task (i.e., "Day-Night"; "Happy-Sad"), which were conducted remotely with a small (N=40) sample of 3-to 5-year-old children of mothers with depression, taking part of a larger clinical trial. During the assessment, children's heart rate at baseline and during each task was measured using wrist-worn heart rate monitors. The tasks showed good feasibility in this sample, as the majority of children (80%) completed both tasks, with wide variability in task performance and completion time observed across children. Correlation analyses showed that older age and slower resting heart rate were related to better performance and faster completion time on each task. Follow-up regression analyses including age, household income, baseline heart rate, and heart rate reactivity as predictors accounted for significant variability in task performance and completion time for the Day-Night and Happy-Sad tasks. In the final models, age was a significant predictor of task performance and completion time across both tasks. Resting heart rate was not a significant predictor of task performance for either task, but was a significant predictor of completion time across tasks; children with slower resting heart rate completed the tasks faster. Despite limitations, our findings support the feasibility of online, remote assessment of executive function in young children with implications for researchers and clinicians during the Covid-19 pandemic and beyond.


This paper presents a system for three-dimensional reconstruction of an object based on photographic images, also proposes a system to acquire multifaceted lower limb ecchymosis images. The three-dimensional reconstruction is done through the feature extraction of several silhouettes from images of the same object. These images must be registered radially with a known angular step. In order to facilitate the acquisition, an automatized electro-mechanic system is proposed, having a camera, a trail system, a support system and the object, which stays steady during the acquisition. Through simulated images, the developed prototypes for tridimensional reconstruction were tested, presenting satisfying results.


Scattering of photons on spin 1/2 particles is investigated for large values of s and finite u on the basis of the Regge pole hypothesis. The expression for the scattering amplitude is reduced to an explicitly factorized form. The main qualitative results are the same as those of Gribov for pi -N scattering. Asymptotic expressions for the differential cross section and some polarization effects are calculated for scattering into large angles. (auth)


PURPOSE: To brew various coffee beverages such as espresso, caffe latte, cappuccino, by roasting multiple coffee beans, mixing predetermined quantity of coffee powder milled to prefered grains, and injecting desired quantities of hot water, steam and milk to infuse. CONSTITUTION: Multiple kinds of beans are selected from coffee bean hoppers 26, 32, milled to prefered size grains by grinders 24, 30, and blended 22 to prefered quantity. Hot water is supplied from a warm water supplying apparatus 34 into a blender 22 to be heated and brewed into a cup 54. And water supplied from a water valve 74 is heated 72 in a steam generator 70 to be high pressure steam. Milk supplied through a milk valve 96 from a milk supplying part 110 is mixed with the high pressure steam and air from a forked air valve 92 by a venturi 90, and made to foamed milk by a vortex mixer 98 to be supplied into the cup 54. If a bottom of an operation part is selected, a series of these operations is carried out by a stored program. As a result, prefered coffee beverage is automatically brewed.


Based on the analysis of shear stress-displacement curve of cemented concrete-rock joint,an assumption is proposed that the shear stress of cemented concrete-rock joint is dependent on the bonding strength and the friction effect of the cohesive interface. A new model of cemented concrete-rock joint considering the bonding degradation after peak stress is therefore established. The comparison of results of back analysis using the proposed model with ones from shear tests shows that the proposed model could describe the entire process of failure of cemented concrete-rock joint. Besides,a stability analysis of the foundation of Furongjiang Bridge is carried out using the proposed model. The numerical results show that the shear stress between the skewback and the bedrock from the bridge loading is smaller than its shear strength;and the shear displacement has a very low value,which indicates a safe bridge foundation.


Collaborative learning supported through computers seems to be very promising due to advances in computer mediated communication tools. However it is not clear which approach for on-line learning - individual or collaborative - is more effective for the students. This paper is a continuation of previous work from the authors, that combines both approaches, taking in account that some advantages related to individual learning, such as the self-pacing and the establishment of learning goals by the learner imply difficulties to establish collaborative settings. In this article a framework is proposed for the management of study groups of distributed learners sharing on-line material. A model is presented to capture the essence of group activities. This information allows further analysis of group and individual performances.


The magnitude of the impact of technological development (Industrial Revolution 4.0) has become a challenge for the world of education to continue to improve, even this situation demands very rapid change, which becomes a serious threat to the world of education, especially the vocational field. There are several problems in concrete rock practice learning such as (low student grades, not yet having teaching materials relevant to the demands of the industrial revolution 4.0, and not optimal use of technology in learning. Research development (R & D) with 4-D models (define, design, develop, disseminate) it aims to answer the challenges of the revolutionary industry 4.0 by creating effective teaching materials and learning strategies with video combination by optimizing the use of technology (smartphone). This research produces module and video that is valid (expert judgment), and effective that can evidenced from the increase in student learning outcomes (average pretest 50.72 and posttest average 86.04). Module teaching materials and video combinations are very suitable to be used for practical learning, especially in concrete stone practice course.


An overview is provided of the utilitarian role that allylindation under aqueous conditions can play in a variety of synthetic contexts. These include the diastereoselective allylation of chiral aldehydes, the consequences of coupling geometrically biased allylic bromides, the realization of 1,4-asymmetric induction, and an analysis of competitive intramolecular/intermolecular chelation options. Also presented are the results of diastereoselective additions to α-oxygenated ketones and to 2,3-azetidinediones. Synthetic applications include a practical alternative to the Knoe-venagel reaction of aliphatic aldehydes, the formation of α-methylcne-γ-lactones fused to medium and large rings, and the intercalation of multiple carbon atoms between the carbonyls of α-diketones.


Lack of safety and regulatory framework currently prevent the routine use of unmanned aircraft systems (UAS) within the U.S National Airspace System (NAS). Demonstrating a level of safety equivalent to that of manned aircraft will allow UAS to fly and interoperate in civil airspace. An unmanned aerial collision avoidance system (UCAS) designed to communicate and interact with the traffic alert collision avoidance system (TCAS) implemented on manned aircraft is proposed. Considering intruding aircraft equipped with TCAS as cooperating aircraft, UCAS will also be able to sense, detect, and avoid non-cooperative aircraft through the use of sensor technology. Simulation and analysis has been carried out to generate a safety metric quantifying the safety of the UCAS system. A Monte Carlo simulation has been performed for a set of outer loop state variables to generate the probability of a near midair collision. A second encounter model is carried out to show the benefits of incorporating the mitigation strategy selected, in this case the collision avoidance capabilities. An existing case study is analyzed to demonstrate the value of the model and the efficiency of the system


Objective To investigate factors influencing postoperative prognosis of elderly patients with intrahepatic cholangiocarcinoma(ICC)in order to improve clinical diagnosis and treatment.Methods A retrospective analysis of consecutive 36 elderly patients(≥65 years old)undergoing hepatectomy for ICC from Oct.1988 to Oct.2007 was performed,and 32 patients younger than 65 years served as controls.The data were analyzed by Kaplan-Meier method and Cox regression.Results In the elderly group,the 1-,3-and 5-year survival rate with radical excision was significantly higher than that with non-radical excision(P0.01).The 1-,3-and 5-year survival rate with a low CEA level(≤10 μg/L)was significantly higher than that with a high CEA level(10 μg/L,P0.01).Multifactor analysis with the Cox proportional-hazards model indicated that radical excision,and CEA level were independent factors influencing the prognosis.Conclusion Operation is the major treatment for the elderly patients with ICC.CEA level and radical excision are major factors influencing the prognosis of elderly ICC patients.


The mechanism of catastrophic degradation of InGaAsP/InP double‐heterostructure light emitting diodes with Ti/Pt/Au electrodes through the application of pulsed large current, is investigated by electroluminescence topography, scanning electron microscopy, energy dispersive x‐ray spectroscopy, and transmission electron microscopy. As the degradation is promoted, a dark region is generated in the center of the light emitting area. This then develops through the whole light emitting area. During the generation and the development process of the dark region, no dislocations are generated. The dark region, which develops through the whole light emitting area, consists of amorphous area and nonstructural small grains. There is clear compositional inhomogeneity in the region corresponding to the dark region. However, the electrode metals are not detected. The mechanism of the catastrophic degradation can be explained by local heating at the contact region by large current pulses, melting of the matrix crystal a...


The study was aimed to evaluate the impact of accumulated oral tegafur‐uracil (UFUR) as maintenance chemotherapy on overall survival (OS) and disease‐free survival (DFS) rates after concurrent chemoradiotherapy (CCRT) for complete remission (CR) in non‐distant metastatic TNM stage IV nasopharyngeal carcinoma (NPC).


Optimal control mathematic model of guided bomb's optimal glide trajectory was established.In order to surmount the draw of the conventional numerical optimization methods' sensitivity to initial values and inner inconsistency between exploiture and exploration of solutions sets of hybrid genetic algorithms based on one improvement strategy,self-adapting mutative scale chaos genetic algorithm was proposed to solve optimal glide trajectory problem.On the one hand,the diversity of population was retained by property of chaos,on the other hand,computational efficiency was improved with mutation scale.Computational results indicate that SAMS-CGA has good performance and significantly improves the computational efficiency in optimization.Optimal glide character of guided bomb was analyzed according to the trajectory simulation.


one which had been thoroughly oxydised by exposure to a current of air in presence of ammonia vapour. To the brownish-black substance resulting he subsequently attached the name of pyraloxin. This he found to possess 110 toxic properties, nor was it liable, as a rule, to excite any dermatitis; it had ceased, in fact, to be erosive, it had passed from the keratolytic into the keratoplasty class. In this altered and mitigated form he recommended it for the treatment of psoriasis and of leprosy, and more recently, compounded into a plaster-muslin with oxide of zinc, in that of lupus erythematosus. When employing it in psoriasis, the peculiar and striking smoothness and burnish of the surface which was left on the fading of the patches led me to try it for the cure ?f that most obstinate and rebellious ailment, eczema palmaris. A paper embodying my observations, and containing the account ?f a series of illustrative cases showing its efficiency in this direction, was read by me before the Medico-Chirurgical Society of Edinburgh in December 1897, and published in the Transactions. Since then it has been employed by me with success in numerous lnstances of this obstinate affection. The following example is specially interesting, as it is that of the youngest patient who has yet come under mv observation with this particular variety of


In a context of globalization and internationalization of markets, optimizing physical movement of goods becomes inescapable. To do this, in this paper, we present our contribution to the implementation of a global system of goods traceability in a multimodal transport context. Thus, we propose a new approach for modeling the data needed to cover the entire goods lifecycle. Then, for the sake of integration of our traceability solution, an integration approach according to a service oriented architecture will be presented, and this by presenting a new ontology for semantic description of web services, dedicated to our traceability solution.


The energy consumption of FTTH network variants is compared with respect to the average access bit rate. The results show that passive optical networks are more energy efficient than point-to-point or active optical access networks.


Populations of the coral Dichocoenia stokesi were quantitatively monitored on reefs of the middle and northern Florida Keys during and after a 1995 epizootic of the coral disease white plague type II. Three large-scale surveys were conducted in the falls of 1995, 1998, and 2002 at selected sites throughout the Florida Keys totaling 8478, 6280, and 8792 m 2 respectively. Between 1995 and 2002, the average number of D. stokesi colonies per 314 m 2 site decreased from 44.3 to 11.2, a decline of almost 75%. We found no evidence of coral recruitment in the 7 yr following the epi- zootic, and have found a continuing pattern of coral population decline. The colony size-frequency distribution pattern on these reefs changed over this time period as well, with the D. stokesi popula- tion exhibiting a trend to domination by large colonies, suggesting that the remaining population, while growing, is no longer reproducing. The shift in population to dominance by large colonies is typical of coral populations on degraded reefs. Here we report the results of a quantitative field study on the Florida reefs and compare these data with a similar study on reefs of Lee Stocking Island, Bahamas, that have not experienced a white plague type II epizootic.


Javanese people has variety arts as part of culture, the one is Barongan. Barongan was born and lived side by side with the lives of the people who owned it. Barongan Kusumojoyo Arts of Demak Regency is one of the Barongan arts found on the east coast of Central Java. Barongan Kusumojoyo art is still maintained its existence until now. The purpose of this study is to examine the form of Barongan Kusumojoyo in Demak Regency. This research is a qualitative research that uses observation, interview, and document study techniques in data collection. The data validity techniques used is the extension of observation, triangulation, and peer examination. The data analysis technique is done by doing data reduction, data presentation, and drawing conclusions. The results showed that the performance process of Barongan Kusumojoyo in Demak Regency consisted of 5 (five) sections, namely (1) jathilan, (2) barongan, (3) songs, (4) jokes, and (5) attractions. The supporting elements of the Brongan Kusumojoyo show in Demak Regency are: (1) dancers, (2) music players, (3) comedians, (4) attractions handler, (5) singers, (6) properties, (7) offerings.


Background: Insomnia is two to three times more prevalent in cancer survivors than in the general population, where it is estimated to be 10% to 20%. Cognitive-behavioral therapy for insomnia (CBT-I) is the recommended treatment for chronic insomnia, but meeting survivor needs remains a challenge. Internet-delivered CBT-I (iCBT-I) has been shown efficacious in otherwise healthy adults. We tested the efficacy of iCBT-I in breast cancer survivors with clinically significant sleep disturbance. Methods: Women from a national sample of Danish breast cancer survivors who experienced clinically significant sleep disturbance were randomly allocated to iCBT-I or waitlist control (55:45). The fully automated iCBT-I program consisted of six cores. Online measures of insomnia severity, sleep quality, and fatigue were collected at baseline, postintervention (nine weeks), and follow-up (15 weeks). Online sleep diaries were completed over two-week periods preand postintervention. Intention-to-treat analyses (time group interactions) were conducted with mixed linear models and corrected for multiple outcomes. All statistical tests were two-sided. Results: A total of 255 women were randomly allocated to iCBT-I (n 1⁄4 133) or waitlist control (n 1⁄4 122). Statistically significant (P .02) time group interactions were found for all sleep-related outcomes from preto postintervention. Effect sizes (Cohen's d) ranged from 0.33 (95% confidence interval [CI] 1⁄4 0.06 to 0.61) for wake after sleep onset to 1.17 (95% CI 1⁄4 0.87 to 1.47) for insomnia severity. Improvements were maintained for outcomes measured at follow-up (d 1⁄4 0.66–1.10). Conclusions: iCBT-I appears to be effective in breast cancer survivors, with additional benefit in terms of reduced fatigue. This low-cost treatment could be incorporated in cancer rehabilitation programs. Insomnia is prevalent in the general population, with an annual prevalence of 10% to 20% (1), and the rates in cancer survivors have been found to be two to three times higher (2). In breast cancer, treatments such as chemotherapy and radiotherapy—and possibly surgery and hormonal therapy—may be partly responsible (3). Although the precise causal pathways are unclear, poor sleep is associated with higher levels of cancer-related fatigue, reduced quality of life (4,5), and perhaps even increased risk of all-cause mortality (6) and cancer recurrence (7). While pharmacotherapy remains the most commonly used option for insomnia (8,9), hypnotics such as benzodiazepine receptor agonists are associated with side effects, dependence, and tolerance over time and are usually not curative, requiring maintenance treatment over many years (10). Cognitive-behavioral therapy for insomnia (CBT-I) (11) is an efficacious nonpharmacological alternative (12,13) and is the recommended first-choice treatment for chronic insomnia (14). Short-term effects are comparable or superior to those found for pharmacotherapy, and long-term effects are maintained for up to three years (15), both A R T IC LE Received: September 20, 2017; Revised: November 23, 2017; Accepted: December 21, 2017 © The Author(s) 2018. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact email@example.com 880 JNCI J Natl Cancer Inst (2018) 110(8): djx293 doi: 10.1093/jnci/djx293 First published online February 20, 2018


Abstract This paper was written in response to the fact that Volume 10, No. 2 of BERJ did not contain a single paper from a teacher currently teaching in a school. There comes a point when you can't just moan about a situation, you have to do something, and this paper is that something. It attempts to describe some of the main reasons for the dominance of 'outsiders' in school‐based research and suggests that this is not a good thing. Possible ways of improving the situation are discussed but no offence is meant to any person living, dead or in suspended animation.


An artificial neural networks modeling (ANNs) for the nanoparticles of palladium (Pd) in the long period fiber Bragg grating (LPFBG) is proposed. A number of simulations have been performed to investigate the characteristics of the proposed approach. The trained and the predicted transmission are compared with the experimental data. The LevenbergMarquardt algorithm has been chosen as the main algorithm because of the lowest mean square error. The model of 20 neurons in two hidden layers shows a better fitting with the experimental data. A new predicted data at 10% H2 concentration has been introduced using proposed ANN model.


In order to study properties of coupled fluid-solid phononic crystals,the finite element method and experimental method were adopted in this paper.In particular,the transmission spectra and the acoustic pressure distributions for the two-dimensional steel/water square-lattice phononic crystal with perfect periods or linear defects were discussed in detail by using ABAQUS finite element software.The associated experiments were also carried out and the range of band gaps were measured by the impulse-response technique.It can be seen that the experimental results are in good coincidence with those of numerical simulation,which shows the superiority of the finite element method in the treatment of coupled fluid-solid phononic crystals interaction problem.


Different techniques are usually employed to evaluate the mechanical properties of arc-sprayed coatings. In many situations, comparing properties is complex, and values extracted from tensile tests are required for structural projects. X6CrNi18-8 stainless steel and molybdenum were sprayed onto a mild steel substrate using the electric arc thermal spray technique to discuss this issue. After a detailed microstructure characterization, tensile tests were performed on both coatings to determine the yield strength and total elongation. Easy techniques were also applied: Vickers hardness and Charpy impact test. Tensile tests have shown that applying coatings increased the steel substrate's total elongation. Molybdenum coating presented a higher impact resistance than the X6CrNi18-8 one, resulting in no correlation between elongation and Charpy values. On the other hand, correlations between hardness and yield strength were identified, opening a discussion on the effects of the microstructure and type of test used.


Summary

Through a detailed case study of a two-species (Lolium rigidum and Avena sterilis) weed community at contrasting scales, this paper examined factors that affect weed distribution across space and time in a commercial wheat field in north-east Spain. A. sterilis showed relatively stable spatial distribution and spatial structure of its population over time at large scale, with well-defined patches, although weed density rose quickly. L. rigidum showed poorly defined patches that were not stable across time. Interaction between species could explain to some degree the spatial distribution at large scale: a negative relationship was detected between the spatial structures of both weed populations. At fine scale, both species showed a clear interaction effect from primary dispersal (more important in A. sterilis) and secondary dispersal from combine harvesting (more important in L. rigidum).


This study evaluated the prophylactic potency of ethanol seed extract of Ricinodendron heudelotii against aspirininduced gastric mucosal injury in albino rats. Gastric ulcer was induced by administering 200mg/kg body weight 24 hourly of Aspirin for three successive days to the experimental animals in group 2-5, group 1 served as control. The animals were grouped into five in the order: group 1: Control, group 2: Reference Treatment (200mg/kg/bw omeprazole), group 3: Treatment 1(50mg/kg/bw ethanol extract Ricinodendron heudelotii seed,), group 4: Treatment 2(100mg/kg/bw ethanol extract Ricinodendron heudelotii seed), group 5: Treatment 3(150mg/kg/bw ethanol extract Ricinodendron heudelotii seed). Data obtained after experimental procedures showed a significant increase in pH of the gastric juice, volume of gastric juice at P≤0.05, absence of Helicobacter pylori and a positive fecal occult blood test than those in the control group. Treatment of the rats with 200mg/kg/bw Omeprazole, 50mg/kg/bw, 100mg/kg/bw and 150mg/kg/bw of ethanol seed extract of Ricinodendron heudelotii for groups 2, 3 4 and 5 respectively, revealed the prophylaxis of the pH and volume of the gastric juice, a negative test result for fecal occult blood and absence of Helicobacter pylori in all treated groups, when compared with the control group (group 1) after 21 days of treatment. This suggests the potency of the ethanol seed extract of Ricinodendron heudelotii to enhance prophylaxis of gastric mucosal injury.


Systemicity as a basic prerequisite for the proper functioning of the state should be manifested in the activities of all its structural components. The purpose of the article: improving the systemic activities of the state of Ukraine. The task of the article is to formulate the principles of systematic activities of internal audit entities.
The purpose of internal audit as an artificial system can be defined as ensuring the effective functioning of the internal control system (compliance with the principles of legality and effective use of budget funds and other assets, achieving results in accordance with the goal, tasks, plans and requirements).
The purpose of internal audit can be considered to diagnose the functioning of the entities in which this information and analytical tool is used.
The purpose of the internal audit system is to process information about the activities of entities.
Main (basic) functions of internal audit: study of the asset control system; checking the compliance of the current control with the company's policy; risk analysis and bankruptcy prevention; use of know-how to increase profits and efficiency of new technology; making other decisions that promote the development of the company. Additional (service) functions of internal audit: providing independent conclusions and recommendations, as provided by Article 26 of the Budget Code of Ukraine.
The basic element of the VA system are structural units internal audit of entities in the provided cases.
Adaptive activity of internal audit is manifested in cooperation with other structural units of state bodies, their territorial bodies and budgetary institutions (including their heads), state bodies, enterprises, their associations, institutions for the organization and implementation of internal audit.
Adaptive activity of internal audit is manifested in the following options of the Units: 1) submission to the head of the state body, its territorial body and budgetary institution of audit reports and recommendations for management decisions; 2) reporting on performance in accordance with internal audit standards.
Internal relations ensure the relationship of coordination and subordination of the above structural elements of internal audit - Units, ensuring their integrity.
External links of internal audit are manifested in the relationship of its structural elements with other business entities (reporting, information exchange, etc.).


Carbon fibre reinforced carbon (CFC) composites have been more and more used in different industrial areas as high temperature materials. Some application examples are CFC components in modern furnaces for heat-treatment and brazing. Because CFC components can react with metallic materials when they contact each other, diffusion barrier coatings are essentially important for such CFC components. The aim of the project IGF 14.880 N "Thermally sprayed diffusion barrier coatings for CFC components in high temperature applications" is to develop diffusion barrier coatings by thermal spraying technology. In the project, different coating systems have been developed and investigated regarding the coating build-up, coating microstructure, bonding, thermal shock resistance and diffusion barrier function. The research results reveal that some developed coating systems are suitable for applications in furnaces. In the present paper, some research results of this project are reported.


Mechanical rice transplanting is gaining attention to the Bangladeshi farmers. However, service business on mechanical rice seedlings transplanting has not yet been developed due to various reasons. The 4-row walking type transplanter (model DP488) was operated in 54 farmer's field at Ghaghatpara, Rangpur  Sadar and Kaliganjpara, Pairaband, Rangpur in late boro 2016 season to explore the entrepreneurial opportunity of commercial mechanical rice transplanting service for small holder farmer in Bangladesh. The field capacity and field efficiency of rice transplanter was obtained 0.15 ha hr -1 and 75%, respectively. Field capacity depended on the size and shape of the plots. Small plots having less than 250 m 2 should be avoided for 4-row walking type rice transplanter to get the good machine performance. Fuel consumption was obtained 4 L ha -1 and varied over plot size, soil settlement time, presence of obstacle, plot to plot travelling distance and operator's skill. Scattered plots increased travelling distance hence fuel consumption raised and reduced daily area coverage. Soil setting time should be allowed for 12-24 hrs for satisfactory machine performance. Mechanical transplanting took 18 man-hr ha -1 whereas mat loading, machine transport and cleaning took 1.6 man-hr ha -1 labors. Depending on the combination of seedling density in tray and density settings in machine the tray requirement varies from 153 ha -1 to 222 ha -1 . Tray distribution was observed as 90% in transplanting, 6% in gap filling and 4% pocket area. Gap filling by manual labor required 18-20 man-hr ha -1 . Time distribution depended on managerial combination and relation between transplanting team and farmers. Seed rate showed negative correlation with seedlings population in tray and positive correlation with seedlings mortality. Number of turning events in plots can be minimized by selecting larger plot and operating transplanter in length-wise. Increasing daily coverage, minimizing fuel consumption and selection of sensible consumer group can draw good return from marginal input and establish business in secure environment. Progressive Agriculture 28 (3): 230-239, 2017


My research interests span a variety of topics in n etwork security and system security. My goal is to provide new capabilities and working systems tha t m ke current networks and systems more secure, reliable, and robust. To achieve this goal, I start from the perspective of "network monitoring and intrusion detection" because they ar e essential components to secure the network, and they serve the basis for further response, miti gation, or prevention. My current work focuses on monitoring and detecting large-scale malware thr ats (e.g., worms, and more recently, botnets). I also work on improving general intrusion and anom aly detection capabilities on traditional, manually-launched attacks. My research philosophy is to start with important and real-world problems , study the problem from novel perspectives, design practical t echniques using sound principle and theory, build real systems, then deploy and test using real -world data or in a real-world environment. To solve practical security problems, I often bridge s ystem and networking techniques with machine learning, statistics, information theory, and appli ed cryptography. I believe that useful research requires a good balance between theory and practice , and should result in real systems to solve real-world problems.


This booklet ... was made possible through Transportation Enhancement Program funds provided by FHWA/MassDOT under an agreement administered by Brona Simon, State Archaeologist and Executive Director at the Massachusetts Historic Commission, and John Rempelakis, Archaeological Resources Supervisor at MassDOT.


A 30-Gbit/s demultiplexer IC has been fabricated and tested using an improved double mesa Si/SiGe heterojunction bipolar transistor process. This is-to our knowledge-the highest ever reported bit rate for "real" (as opposed to drift transistor) Si/SiGe HBT circuits. The result was mainly reached by scaling down the transistor sizes to reduce parasitics. The minimum emitter mesa width was 1 /spl mu/m.


Abstract Exercising in hot and especially humid environment can cause rise in body core temperature to such a critical level that it does not only reduce performance, but also may ultimately lead to exertional heat stroke (EHS). This illness is true medical emergency that can result in significant morbidity and mortality, if not early recognized and promptly treated. Diagnostic criteria for EHS are body core temperature above 40°C and central nerve system dysfunction. Any athlete experiencing such symptoms should be immediately exposed to aggressive cooling treatment aimed to lower the elevated core temperature to near normal as quickly as possible. Ice water immersion is highly recommended as a cooling method because it provides the fastest cooling rates and is associated with lowest mortality rates. Athletes cooled rapidly soon after the onset of EHS usually recover without complications and are able to return to normal training in hot environment within a few weeks. EHS is also a preventable condition, and its occurrence can be minimized by implementing a few simple measures.


Seven cases with fracture-dislocation of the 4th and 5th carpometacarpal joints were treated during the past eleven years. These cases were followed for an average of 3 and their years and 3 months. Six cases were male whereas one case was female, ages ranged from 20 to 60 years (average, 33.9 years). Closed reduction was performed in fresh cases, following cast immobilization. Open reduction was performed in 1 fresh case and 5 old cases, following temporary K-wire fixation. In the old cases 7 months after injury, it was very difficult to reduce the dislocation, even surgically. All cases had excellent results.


Salience, a concept little analyzed in linguistics/pragmatics, is defined here as that quality which determines how semantic material is distributed within a sentence or discourse, in terms of the relative emphasis which is placed on its various parts. This article explores the concept of salience as it is manifested in the performance of one speech act, that of defining. The salience of definitions functions on two levels: salience of the various information components of the speech act in relation to each other, and salience of the overall speech act within the total discourse. The former is interpreted in terms of "functional sentence perspective." The latter is created internally by precision of propositional content, pragmatic function, syntactic form, distribution of information, lexical "boosters" and "downtoners," and repetition; externally by "grounders" and "confirmations" and paralinguistically by emphatic stress, graphic, and other visual reinforcement.


Data fusion methods are widely used in autonomous robots' measurement system in order to acquire more comprehensive and more exact information. Multi-sensor data fusion is to combine multi-sensor's information, which is redundant or complementary in the space or the time to obtain the uniform description or the understanding to the measured object according to a certain criterion. Move-in-mud robot is an autonomous robot, which can excavate hole in the mud underwater. It can be used in sunken wreck salvage to improve the efficiency of excavating the hole. Location system of move-in-mud robot is designed in the paper and location principle of move-in-mud robot is analyzed. Fuzzy Kalman filter arithmetic is applied and simulated in location system of move-in-mud robot to fuse redundant information of the robot. The simulation results show the data fusion method can improve location accuracy.


Floyd raises concern about several "sports" and "detox" drinks having potassium concentrations over 80 mg/100 ml, as well as "one with …


The West New Guinea conflict between Indonesia and the Netherlands teetered for months on the brink of war in 1962. The August 15, 1962 agreement appeared to offer a preferable alternative. Both sides made significant concessions although the major one by Indonesia (to grant "freedom of choice" to the inhabitants of the territory) seems to depend entirely on her willingness to abide by an international agreement. The policy of "total confrontation," adopted by Indonesia in the latter stages of the conflict, paid off, but not without a price. Lives were rather carelessly sacrificed and an estimated 80% of the 1962 budget was devoted to military expenditures. Massive foreign loans were the life-buoy of the economy. Buckpassing, multiplication of functions, and corruption had become common in the administration. The present super-inflation' practically sanctions dishonesty and pardons corruption. These conditions are not favorable for the task awaiting Indonesia in West Irian. That the Indonesians would display some ignorance about life and conditions in West Irian was to be expected, as was their reluctance to admit this lack of knowledge. Most of the Indonesian slogans were based on false and contradictory concepts reflecting stereotypes of Western colonialism and capitalism. Indonesia adopted the view that illiteracy and primitivity (as revealed by nakedness) were almost complete; that a "colonial mentality and subservience" prevailed; and that all inhabitants were eager to be liberated by their Indonesian brothers from Dutch colonial oppression. Knowing how the Dutch had fared economically in Indonesia, a similar basis of economic achievement was expected in West Irian. And, finally, it was confidently assumed that the penny-wise Dutch would never have poured millions of guilders into the area without anticipating a huge financial return. Already, West Irian has proved a great disappointment. Some of Indonesia's responsible officials realize that administering the territory, maintaining its transportation and aviation system, advancing education and health standards, and encouraging economic development present a tremendous challenge and a long-term burden on the Indonesian economy and balance of payments. They are also aware of the problem of dealing with the Papuan inhabitants without appearing colonial. Some Indonesians and foreign visitors now accuse the Dutch of "having spoilt" the townsfolk


This case exemplifies the fact that how despite tremendous technological innovation, an organization faces extinction due to market innovation by its owners. This case serves a point of refute to the traditional management thinking that positively links technological innovation to unremitting competitive advantage. The success of DTI to meet their customer's (IBM and Toshiba, who were also it's owners) requirement and overcome the manufacturing bottlenecks is an example of managing radical technological innovation. It was Toru Shima's (President, DTI) vision of mixing the right strategies due to which they not only met the requirement of 100,000 units per month but also overcome the hurdles imposed by the complex technological and manufacturing process. As a result the production not only doubled but also tripled. But due to the increased competition and slumping that led to increased pressure on the manufactures of LCDs, led IBM and Toshiba seek for different market focus. While Toshiba saw opportunity in mid-to small scale sized LCDs display for cell phones and hand held devices, IBM focussed on larger, high resolution LCDs for computer monitors. This ended their common vision, which led to the formation of DTI. Thus, traditionally it could be said that the fate of DTI was inevitable and should not be discussed along with the lines of organizational failure or death/extinction. Yet such school of thought may not entirely impede a debate whether such a fate could have been reversed. Death of a firm is an inevitable alternative to self-renewal. A successful firm should always adapt itself or even change the ecosystem to its favor in which it belongs, it were to survive beyond a Strategic Infection Point (SIP). The market innovation of IBM and Toshiba had triggered a Strategic Inflection Point (SIP) that DTI should have realized and acted accordingly.


For the problems of the low contrast and fuzzy flaw edge in X-ray ammunition image,an adaptive local fuzzy enhancement approach based information entropy was presented.It first dynamically normalized the ammunition image,obtained the regions of interest by gradient operator,and automatically selected the best crossover point gc with OTSU algorithm in order to get the transition μc of fuzzy enhancement operator.It then used the improved membership function to nonlinearly fuzzy process the gray value on the two sides μc to obtain the enhanced ammunition image.Experimental results demonstrated that the proposed approach could efficiently improve the contrast of the ammunition image and enhanced the flaw information.


In view of the disadvantage of the traditional SCR phase-control rectification hydrogen preparation power supply,a new diode rectification with multiplex chopper topology is introduced,which is used in large capacity hydrogen preparation power.DSP+FPGA controller is designed,with a variety of failure protective and display functions.Then a multiplex large capacity hydrogen preparation system is developed.The simulink and the running states are very good.


BACKGROUND
Antiagiogenesis represents a promising approach to cancer therapy. We have previously demonstrated that the antitumor effects of endostatin, one of the most potent angiostatic agents, could be enhanced when combined with immunotherapy. Our current study evaluated whether anti-tumor immune response could also potentiate the therapuetic efficacy of another antiangiogenic drug, angiostatin.

METHODS AND RESULTS
Using Matrigel assay, we showed that our preparation of recombinant angiostatin possessed potent anti-angiogenic activity in vivo. The antitumor effects of recombinant angiostatin were tested against weakly-immunogenic 3LL Lewis lung carcinoma versus its highly immunogenic variant 3LL-C75. We showed that angiostatin inhibited the growth of 3LL-C75 more potently than that of 3LL tumor, suggesting that the host's immune response potentiates the antitumor effects of angiostatin. This conclusion was further supported by the finding that the antitumor activity of angiostatin against 3LL-C75 tumor was lower in immunodeficient nude mice in comparison with immunocompetent mice. Immunization of C57BL/6 mice with 3LL-C75 cells stimulated the antitumor immunity and inhibited the growth of parental 3LL tumor. Angiostatin treatment of immunized mice further enhanced the antitumor effect of tumor vaccination.

CONCLUSION
Antitumor immune response could complement the therapeutic efficacy of angiostatin.


Calibration curves for the Apollo 16 command service module pulse code modulation downlink and onboard display are presented. Subjects discussed are: (1) measurement calibration curve format, (2) measurement identification, (3) multi-mode calibration data summary, (4) pulse code modulation bilevel events listing, and (5) calibration curves for instrumentation downlink and meter link.


This is a study about the new supplement in the Swedish law of discrimination; Transgender identity or expression, means that someone does not identify herself or himself as a woman or a man or expresses by their manner of dressing or in some other way that they belong to another sex. The purpose with this essay is to discover different perspective to understand the new supplement. The research questions were: (1) How is it possible to understand this new supplement? (2) How is it possible to read the meaning of identity in relation to this supplement? To analyse this questions I have used queerfeminist theory and the concept of discourse analyse. The findings showed that there is a big tension to be defined within a category as a transgender person and the right to be recognized even outsides this frames as a constantly fluently individual. My conclusion is that the new supplement both appear to include but also exclude people to get protection against discrimination. (Less)


The initial new patient visit in our office is complimentary. At this time, it will be determined whether orthodontic treatment is indicated. If treatment is recommended, Orthodontic Records will be needed. Orthodontic Records are a necessary aspect of the treatment process. These Records are performed to document current teeth alignment, bone structure and jaw growth prior to orthodontic treatment. Measurements are taken using x-rays and models to determine how treatment will proceed.


Abstract Mating and laying sites of Uromenus brevicollis insularis, a Cyrno-Sardininian micro-endemic species, are described from observations conducted at night in several Corsican localities. Asphodelus ramosus was found to be a key host species as both mating and oviposition of this insect take place mainly on the erect dry stems of the plant. Some aspects of the meeting of the sexes are assessed: male stridulation does not appear to play an important role. The females lay their eggs, creating vertical lines in the stem by chewing regularly spaced holes containing nearly 3 eggs per hole. One to three laying lines can be observed on a single stem. Ferula communis is frequently used as an alternative laying site when A. ramosus is absent or rare, but in this case, the eggs can be attacked by woodpeckers (Dendrocopos sp.) or parasitized by Hymenoptera.


A utility program executing on a mobile communication device decides whether to launch an application remotely as a Webapp or whether to launch the application locally on the mobile communication device. The decision is based at least in part on an estimate of how much of a resource the application would consume were the application to be launched and executed on the mobile communication device. Examples of resources include battery capacity, memory capacity, and processing power capacity. If the total amount of a resource consumed by currently executing applications and the application to belaunched would exceed a threshold amount, then the utility uses a browser on the mobile communication device to launch the application remotely as a Webapp, otherwise the utility program causes the application to be launched locally. The utility program has a graphical user interface (GUI) whereby utility program operation can be configured and customized.


The crashworthiness of auto?body structures is one of the important issues in the automotive industry. The crash analysis with finite element methods has been conducted in order to evaluate the crashworthiness of auto?body structures. In the car crash, auto?body structures undergo deformation with a wide range of strain rate from 0.001/sec to 500/sec. Since the material properties of steel sheets depend on the rate of deformation, in order to ensure the impact characteristics of auto?body structures accurately, the dynamic behavior of sheet metals must be examined and applied to the finite element model appropriately. This research is concerned with standard uncertainty evaluation of tensile properties of auto-body steel sheets in wide range of strain rate from 0.001/sec to 100/sec. Stress-strain relations of an auto-body steel sheet were obtained with quasistatic and high speed tensile tests. Uncertainty components in both testing methods are summarized and standard uncertainties of each input quantities are evaluated. An analytic model is established in order to calculate combined standard uncertainty of the measurand. The measurand is true stress with respect to true strain and the input quantities are load and displacement data during the tensile test and initial dimensions of specimen such as thickness, width and length. Uncertainties which come from signal processing and deviation of measured values in repetitive tests are also considered.


ry, while the Maros Chronicle presented here both is more fleshed out in terms of contents and continues the story down to the nineteenth century. As such, this Maros Chronicle represents an important new source of historical information about pre-modern South Sulawesi. This article first discusses the manuscript itself. Then a transliteration and translation of the text is given. This is followed by sections discussing what the text reveals about the history of Maros, what it suggests about the writ ing of chronicles in Makassar, and how it may relate to and illuminate events during the period in which it was written. Any historical text stands at an intersection from which we can look in three different directions: a referen tial reading tells us of the past it recounts, a narrative reading tells us how accounts of the past were constructed, and a contextual reading tells us of the social and political context in which it was written. What we see when we look at Indonesian historical manuscripts depends to a large degree on which of these readings we prefer. We begin our readings with a consideration of the Maros Chronicle manuscript.


The atmospheric corrosion behaviors of AZ80 magnesium alloy are investigated by exposure test in different testing sites. After four months exposure test, the corrosion morphologies and the component of the corrosion products were observed by the scanning electron microscopy (SEM) equipped with energy-dispersive analysis of X-ray (EDAX). The corrosion rates of AZ80 magnesium alloys were calculated by mass-loss. The results indicated that the corrosion resistance of AZ80 magnesium alloy in the sea environment is the worst. The corrosion degree of the back surface is worse than the front side. The corrosion products are mainly formed by carbonate, and contain small amount of chloride in most environments, while in Xishuangbanna and Jiangjin area contain a little sulfate.


A fair amount of Canadian taxpayers spend a substantial period of the year in the United States while retaining their Canadian resident status. New income tax rules in the United States related to the notion of residence play an important rule in the planning of the life of a taxpayer. The first part of this paper focuses on the American legislation in order to warn the taxpayers about the potential income tax consequences of spending time in the United States.
 The second part of this paper analyses the U.S. income tax legislation related to Canadian taxpayers who invest in U.S. real estate. Should the taxpayer use a corporation to hold the investment? Should that corporation be Canadian or American? These questions trigger a number of potential tax problems, some of which are discussed in this paper.


The functional condition of organism and adaptable opportunity of cardiovascular system are investigated at pregnant healthy women of young age, and also pregnant women with preeclampsia.


The invention discloses a lycoris aurea cultivation method under a poplar and lycoris aurea composite cultivation pattern. The lycoris aurea cultivation method comprises the following steps: a timber-oriented poplar forest is selected, wherein the poplar forest has loose and fertile soil, the soil is approximately neutral, and the poplar forest is near a water source; soil preparation and bedding are conducted on poplar forest land; lycoris aurea seedballs are prepared; planting furrows are formed in the poplar forest land which is subjected to soil preparation, wherein the lycoris aurea seedballs are placed in the planting furrows according to row spacing, covered with soil, and finally watered for fixing roots; daily field management is conducted after the lycoris aurea seedballs are planted, wherein the daily field management comprises timely grass gathering in spring and summer, timely fertilization and timely hydrops removal; the lycoris aurea seedballs and fresh cut flowers are harvested in time. By the adoption of the lycoris aurea cultivation method under the poplar and lycoris aurea composite cultivation pattern, the biological characteristics of poplar and the biological characteristics of lycoris aurea are given play to, light, heat, space and other ecological conditions of a forest can be made the most of, cost input of production materials and labor added due to compound management are deducted, and the pure profit can be increased by over 20 percent. The local landscape and ecological benefits can be improved, the economic benefits of a poplar forest are enhanced at the same time, and the poplar industry chain is further extended.


P1'arginine of the substrate SNAP-25 is an absolute requirement for catalysis, and the active site of botulinum neurotoxin serotype A (BoNT/A) is populated by acidic residues. We reasoned that arginine derivatives, and basic peptides might bind to the proteolytic domain, and act as inhibitors. A systematic investigation of amino acids, derivatives and basic peptides provided proofs of our concept. D-arginine, arginine hydroxamate and basic peptides effectively inhibited BoNT/A activity. Optimisation of the peptide inhibitors resulted in a RRGC tetrapeptide displaying 90% inhibition at 20 microM. Our studies provide an inhibitor scaffold for potential development as a BoNT/A drug candidate.


The proposed circuit is a basic electric circuit that produces chaos whcih consists three energy storage devices, a dissipative device, and a non-linear device. This paper investigates the use of a memristor as the nonlinear device in Chua's circuit. The memristor is represented mathematically by the port equation and the state equation. The memristor state is defined by the past and present values of input voltage rather than by a piecewise linear or cubic polynomial function. The proposed circuit shows that the circuit undergoes chaotic oscillations that are sensitive to the initial conditions.


BSP is the rock-bottom software which is used to implement hardware independence in embedded system.The function of BSP is to configure and manage the appointed hardware.With the development and popularization of the embedded system,its size becomes larger and larger. And the complication of BSP enhances sharply,too.The traditional developing method of BSP is already not seasoned with the development of the embedded system.Many problems emerged in BSP developed by traditional method,such as repeated development,bad universalization of the code and huge workload of maintenance.Modularization programming is an important thinking in modern software development.It can distinctly enhance programming efficiency, shorten developing periods and enhance the stability of the system.This paper gives an idea to apply the modularization thinking in BSP development based on analyzing the abuse of traditional developing method of BSP.


Smart face identification is widely used in smart city and smart healthcare. However, smart face identification technology is susceptible to envirnmental factor, such as illumination, mask, and expression. In order to fully extract facial feature information, we fuse an improved local binary pattern (LBP) and the histogram of oriented gradients (HOG) to extract the texture and detailed features on the face. The 2DPCA + PCA is used to reduce the dimensionality of the extracted features. The 2DPCA sloves the issue that the model is too complex when the feature dimension is very high. The feature reduction reduces the calculation scale and increases the calculation speed. Finally, experimental results on ORL and Yale face databases show that the feature extraction based on the fusion of improved LBP and HOG complement with each other. Compared with other recognition algorithms, the improved algorithm has higher recognition and identification rate.


It is highly impossible to differentiate between verified and fake media news and updates with modern emerging technology. The creation of deeper fake photos and videos which use artificial intelligence (AI), that shows someone saying and doing things that never did in reality, is one of the recent innovations that contribute to it. Concentrated depths will easily hit millions of citizens and affect adversely our culture, along with their accessibility and pace of social networking. This paper analyses a variety of widely accessible internet news stories, while literature on this subject is scarce, in order to explore the depths, and who creates them, how deep technological advantages and risks are, which example of deepfake occur and how the depths are to be gauged. We will use qualitative research methodology to gather the available information and based on the findings, in the end, we will conclude the discussions along with recommendations.


Brain computer interfaces are an important tool to enable communication for patients suffering from amyotrophic lateral sclerosis. Yet most existing devices use cognitive functions that are impaired in later stages of the disease. Systems based on higher cognitive processes provide new possibilities for this field. However, many patients in the target group suffer from memory impairments. As many higher cognitive processes involve memory, this could be an interference. The present study investigates the differences between a currently existing cognitive paradigm using autobiographic memories and a new paradigm using a guided imagery story. Both are developed to be used in patients and try to target the same processes, with the new paradigm being less dependent on memory functions. Assessment of EEGand behavioral data in healthy subjects results in two working paradigms for brain computer interface control. Higher classification accuracies and more favorable behavioral ratings are achieved by the previously existing paradigm.


The development goals of the sport performance major are established in three aspects,such as talent development,scientific research and social service and the core of the goal is to cultivate the practical talents.The development ways of the sport performance major include satisfying students' learning needs,absorbing the scientific findings and actively participating in the social service.


P hysical educators often object when their classes are used as laboratories for reading and writing instruction (O'Brien & Stewart, 1990; Tannehill, Romar, & O'Sullivan, 1994). Yet, their argument that class time should be used solely for movement only serves to perpetuate the myth that physical activity is somehow isolated from the rest oflife and, in the case of schoolchildren, from education. If physical performance is to be effective, more than just movement practice is required. Unfortunately, little is found in the professional literature to help preservice and inservice teachers see the links between physical education and literacy. In fact, until recently, few preservice programs in secondary education required potential physical educators to take courses in language and literacy. This reluctance to include literacy in physical education may be based on confusion about the difference between general literacy skills and content literacy. As McKenna and Robinson (1990) explained,


A high-frequency, asymptotic solution for transient head,appropriate for a medium containing smoothly varying heterogeneity,provides a basis for efficient inverse modeling. The semi analyticsolution is trajectory based, akin to ray methods used in modeling wavepropagation, and may be constructed by post processing the output of anumerical simulator. For high frequencies, the amplitude sensitivities,the relationship between changes in flow properties and changes in headampliude, are dominated by the phase term which may be computed directlyfrom the output of the simulator. Thus, transient head waveforms may beinverted with little more computation than is required to invert arrivaltimes. An applicatino to synthetic head values indicates that thetechnique can be used to improve the fit to waveforms. An application totransient head data from the Migration experiment in Switzerland revealsa narrow, high conductivity pathway within a 0.5 m thick zone offracturing.


To treat the SARS-CoV-2 virus, that enters the body through the respiratory tract, different vaccines in particular against the SARS-CoV-2 spike (S)-protein have been developed or are in the development process. For the BioNTech / Pfizer mRNA vaccine BNT162b2, which is injected twice, protection against COVID-19 has been described for the first weeks after the second vaccination. The underlying mechanisms of defense and the long-term effectiveness of this vaccine against COVID-19 are currently under investigation. In addition to the induction of systemic antibodies (Abs), Ab responses in the respiratory tract would help to form a first line of defense against SARS-CoV-2. Furthermore, protection depends on Fab-part-dependent neutralizing capacities, however, Fc-part-mediated effector mechanisms might also be important. Long-term defense would be based on the induction of long-lived antibody-producing plasma cells (PCs) and memory B cells. Here, we established different assays to analyze anti-SARS-CoV-2-S IgG and IgA Abs in blood serum and saliva as well as SARS-CoV-2-S1-reactive IgG and IgA PCs and potential memory B cells in the blood of individuals upon their first immunization with BNT162b2. We show that the vaccine induces in particular anti-SARS-CoV-2-S IgG1 and IgG3 as well as IgA1 and in some individuals also IgG2 and IgA2 serum Abs. In the saliva, we found no anti-SARS-CoV-2-S IgA, but instead IgG Abs. Furthermore, we found SARS-CoV-2-S reactive IgG+ blood PCs and potential memory B cells as well as SARS-CoV-2-S reactive IgA+ PCs and/or potential memory B cells in some individuals. Our data suggest that the vaccine induces a promising CD4+ T cell-dependent systemic IgG1 and IgG3 Ab response with IgG+ PCs and potential memory B cells. In addition to the systemic IgG response, the systemic IgA and saliva IgG response might help to improve a first line of defense in the respiratory tract against SARS-CoV-2 and its mutants.


In order for a unit to procure goods/services over $5000 from a vendor, the vendor must have a purchase order in hand. Failure to obtain the purchase order prior to committing to buy goods/services results in an After the Fact (ATF) purchase. When an ATF occurs, the responsible unit must investigate and write an explanation to the Vice Chancellor for Budget and Finance. This memorandum must explain how the charge was incurred and include a description of the goods/service, a dollar amount, how the vendor was chosen, an assessment of whether the rates were fair and reasonable, a confirmation of resources available to pay the ATF, controls in place to combat future infractions, etc. The Vice Chancellor must then prepare a memorandum approval request to submit to the State Controller's Office and copied to the President or Chancellor and the Procurement Service Center. If the ATF is approved, the unit processes a Purchase Order Requisition in the finance system. The Procurement Service Center then issues a Purchase Order. Up until that time, the vendor receives no payment. If the ATF is not approved, the individual responsible for ordering the goods/service is obligated to pay for the purchase personally. The University may not reimburse the individual. The only other course of action is to return the goods, explaining that the University is under no obligation to pay for them. Unfortunately, a service cannot be returned. Please remember to plan purchases as far in advance as possible. There are several steps to procuring a purchase order and the process can be lengthy.


Coal when mined contains a certain amount of inherent or chemically bound water, which necessarily forms part of the product. In the course of upgrading or 'washing', the raw coal is crushed and a high-grade product obtained by heavy media separation; the fines are cleaned via spirals and dewatered before being admixed to the coarser product for sale. The cleaning process thus involves the contact of coal with water. The amount of this additional free moisture remaining in the dewatered product is particularly prominent for the fine coal fraction because of the high surface area to which water can adhere, and water being occluded in the inter-particle voids of the dewatered cake. A high amount of moisture in coal is undesirable for a number of reasons: it may lead to spontaneous combustion when stored; it increases the stickiness of coal, resulting in blocked chutes and hang-ups in bunkers; it adds to storage and transportation costs, which are charged by mass; and finally, but not least, moisture reduces the heating value of coal. It has been found that reducing the moisture by 10% increased the heat rate in a lignite-fired power station by over 4%, taking a number of factors into account1. Processes to reduce the free moisture of fine coal include filtration (vacuum and pressure filters), centrifuging, and warm air drying in fluidized-beds reactors1. Bituminous coal produced at the Goedehoop Colliery typically contains 3% inherent moisture. The < 5 mm fine coal fraction is dewatered by centrifuging, resulting in 20–23% residual free moisture. The target for total moisture being 15% implies that free moisture should be reduced to some 12%. Common methods used to lower the finecoal cake moisture include the addition of suitable chemicals, either flocculants to produce larger coal particles, or surfactants to modify the coal surface-water interface2. Various models as to the beneficial role of surfactants and the likely mechanism of improved drainage are advanced; none, however, is as yet conclusive3. Probing tests were carried out at the Goedehoop Colliery, a division of Anglo Coal located in Witbank, to observe the effect on residual free moisture of two different surfactants that were added to the fine-coal feed to the centrifuge. The results obtained by this limited and rather unsophisticated plantscale testwork were first presented at a student colloquium4. The presentation here is meant to elicit some discussion from a wider audience because of the rather interesting findings.


A 64-year old woman presented to our institution with complaints of dyspnea, fatigue and palpitation for last 10 years. The patient had undergone surgery for ostium secundum atrial septal defect twenty years ago. Echocardiography showed presence of severe aortic valve regurgitation. In spiral thorax tomography, type-A dissection (6.5 x 7 cm in diameter) of the ascending aorta was revealed. The dissection involved the aortic root and extended toward arcus aorta (Fig. 1). We have performed MR angiography in order to evaluate coronary arteries and obtained normal results. The patient was referred for surgery with the diagnosis of the type-A dissective aortic aneurysm and 3rd degree aortic valve regurgitation. In the operation, an aneurysm beginning from the aortic root level of ascending aorta and ending at the immediate proximity of innominate artery was detected. The ascending aorta was excised longitudinally. The dissection was ending with double lumen. There was an intimal tear at the site where the aortic cannulation was done (Fig. 2). There was damage of the aortic valve structure and it was not appropriate for repair. For this reason, a number 23 Carbomedics brand prosthetic aortic valve was placed in the aortic annulus after a graft anasthomosis of 28 mm Dacron tube. After reimplantation of the coronary arteries, an end-to-end anasthomosis between the distal graft and distal aorta was made. The patient was released from the pump without any problem and was discharged from the hospital a week later. Some of the iatrogenic aortic dissections of cardiac surgical operations may be localized and remain asymptomatic for a long period of time in the form of chronic dissective aneurysm. Nevertheless, these types of dissections may eventually result in an aneurysm that would cause aortic valve regurgitation (1, 2). Therefore, it is important for the patients to undergo radiological and clinical examinations periodically. Preoperative identification of high-risk patients, appropriate preventive measures and careful surgical manipulations may reduce the risk. Furthermore, routine monitoring of the patients suspected for perioperative dissections is important for prevention of aneurysm formation, related symptoms and mortality.


The extracellular matrix (ECM) has historically been explored through proteomic methods. Whether or not global transcriptomics can yield meaningful information on the human matrisome is unknown. Gene expression data from 17,382 samples across 52 tissues, were obtained from the Genotype-Tissue Expression (GTEx) project. Additional datasets were obtained from The Cancer Genome Atlas (TCGA) program and the Gene Expression Omnibus for comparisons. Gene expression levels generally recapitulated proteome-derived matrisome expression patterns. Further, matrisome gene expression properly clustered tissue types, with some matrisome genes including SERPIN family members having tissue-restricted expression patterns. Deeper analyses revealed 388 genes varied by age and 222 varied by sex in at least one tissue, with expression correlating with digitally imaged histologic tissue features. A comparison of TCGA tumor, TCGA adjacent normal and GTEx normal tissues demonstrated robustness of the GTEx samples as a generalized control, while also determining a common primary tumor matrisome. Additionally, GTEx tissues served as a useful non-diseased control in a separate study of idiopathic pulmonary fibrosis matrix changes. Altogether, these findings indicate that the transcriptome, in general, and GTEx in particular, has value in understanding the state of organ ECM.


This paper presents a method to synthesize hardware functional asynchronous monitors from a formal representation. It is essential to get correct information and avoid erroneous messages from these monitors that check properties on synchronous designs. Asynchronous Quasi-Delay Insensitive (QDI) designs are very robust to the environment variations; they remain functional in a wide range of power supplies or temperatures. Uniqueness of the claimed approach lies on the use of QDI technology to construct the monitors leading them to be more robust than synchronous monitors in safety critical environment.


The perovskite oxides are strategic materials due its catalytic, electronic and magnetic properties. These properties are influenced by the calcinations and synthesis conditions. This work describes a study on the synthesis of LaNiO3 perovskites via modified proteic gel method varying the content of collagen. Perovskites oxides with the composition LaNiO3 were synthesized by modified proteic gel method using nickel nitrate, lanthanum nitrate and collagen as starting source. The obtained powders were characterized by thermogravimetric analysis (TGA), infrared spectroscopy (FTIR) and X-ray diffraction. TGA curves and FTIR spectra were particularly useful in establishing of the optimal calcination temperature of the precursor powders. X-ray diffraction patterns revealed the formation of the perovskite structure in all samples prepared by synthesis method varying the content of collagen and after calcinations at 700 °C four 2 hours. In the optimization of the collagen content, the bester bulk proportion of metal (Ni2+)/collagen used was 1.0:1.0, where it was possible to obtain monophasic perovskite.