Other subjects are not immune to attack and doubt. One common room familiar to me reverberates still with a challenging riposte in the context of a discussion about geography: "Look, either Johannesburg is in South Africa or it isn't-where's the subject?" The subject in question in Colin Evans's book is modern languages. Its origins as an academic discipline demonstrate how much doubt surrounded the very notion of making modem languages the object of university study. In Cambridge the dismissive term 'courier tripos' was coined to describe the upstart newcomer to the University's academic courses, first examined in 1886. When a statute of 1903 established the Final Honour School of Medieval and Modern Languages in Oxford it was the culmination of efforts in the University which had been frustrated one way or another since 1724 [1], such was the distrust and fear of 'modern' studies. A quondam Chichele Professor of Modern History demonstrated the prejudices in his autobiography:


Introduction: Congenital alteration in the urinary tract represents 20 to 30% of pediatric patients with end-stage renal disease that required kidney transplantation. Poor bladder emptying and the pooling of mucus may result in an increased incidence of bladder stone formation and infectious that may produce reject and graft loosing. In neuropathic bladder, various tubular structures have been proposed as alternative to drainage the urine. The mean important in this case is to report the outcome in the first intraperitoneal laparoscopic Mitrofanoff procedure using ureter concomitant a native nephrectomy in a child with kidney transplant in our center (Centro Médico Nacional Siglo XXI "Hospital de Pediatría Dr. Silvestre Frenk Freund" IMSS*. Case Report: An 11yearold female child of 16 kg of weight and 1.3m of size with kidney transplantation had 4 months' history of recurrence urinary track infectious due to a neuropathic bladder and left native kidney hydronephrotic. Intraperitoneal laparoscopic: ureterocutaneostomy concomitant left native nephrectomy was performed, like continence derivation in this child, to drainage the urine and prevented deterioration of graft function. Conclusion: Laparoscopically, the ureter was used to create a continent conduit between bladder and skin without closing the bladder neck. The patient had a good outcome and we recommended a meticulous dissecting to the ureter-bladder union that should be used like a continence valve; at the same time, it is better placing a drainage for 1-2 days by an historical hydronephrotic with kidney infectious. Correspondence to: Pierre Jean Aurelus, Hospital de Pediatría Centro Médico Nacional Siglo XXI (Instituto Mexicano Del Seguro Social "IMSS"), México, Tel: +525556276900; E-mail: email@example.com


Surveillance video systems are gaining increasing attention in the field of computer vision due to its demands of users for the seek of security. It is promising to observe the human movement and predict such kind of sense of movements. The need arises to develop a surveillance system that capable to overcome the shortcoming of depending on the human resource to stay monitoring, observing the normal and suspect event all the time without any absent mind and to facilitate the control of huge surveillance system network. In this paper, an intelligent human activity system recognition is developed. Series of digital image processing techniques were used in each stage of the proposed system, such as background subtraction, binarization, and morphological operation. A robust neural network was built based on the human activities features database, which was extracted from the frame sequences. Multi-layer feed forward perceptron network used to classify the activities model in the dataset. The classification results show a high performance in all of the stages of training, testing and validation. Finally, these results lead to achieving a promising performance in the activity recognition rate.


This paper describes the importance of Solfeggio in music education and what professional quality Solfeggio teachers should have in the new era.It also introduces the influence of teaching innovation,humanities and aesthetic judgment on Solfeggio in detail in Solfeggio lessons to improve the breadth and height of students' learning in music.


This study aimed to explore future life orientation and support that needed to accomplish it. A total of 258 participants are Javanese high school student. The age of the sample ranges from 14 to 18 years old. Participants were asked about their future aspiration, their reason of choosing them as important goals in their life, and support that they need to accomplished their goals using open ended questionnaire. The responses were categorized through content analysis into four main categories. They are: (1) Self Fulfillment (72.1%) (2) Parents and Family (16.7%) (3) Altruism (8.1%) (4) Social and Economy Status (3.1%). Meanwhile, the categories for support that they needed are shown as follows: (1) Affection Support (64.7%) (2) Spiritual support (17.4%) (3) Material Support (10.9%) (4) Guidance Support (7.0%). The research found that affection support always gets the highest number in every future orientation categories. It can be concluded that although Javanese adolescents have different future orientation, they basically need affection support. Keywords—Affection support, future orientation, indigenous psychology, Javanese adolescent


Introduction:
 Neo-aortic root dilation (ARD) is common after arterial switch operation (ASO) for D-loop transposition of the great arteries (TGA). We sought to compare short and long-term outcomes for bicuspid native pulmonary valve (BNPV) patients to those with normal trileaflet variants (TNPV).

 Methods:
 A retrospective cohort of TGA patients undergoing ASO at Boston Children's Hospital from 1989-2018 was analyzed, matching BNPV patients 1:3 with TNPV patients by year of ASO; those with >mild subpulmonary stenosis or complex TGA were excluded. Categorical and continuous variables were compared using Fisher's exact and Wilcoxon rank sum tests, respectively. Kaplan-Meier analyses with log-rank test compared groups for time to first reoperation on the neo-aortic valve, first occurrence of ≥moderate neo-aortic regurgitation (AR), and ARD defined as root z-score ≥4. Hazard ratios were estimated based on the Cox proportional hazards model.

 Results:
 A total of 83 BNPV patients were matched with 217 TNPV. BNPV patients were more likely to have a VSD (75% vs 44%, p <0.001). Early surgical outcomes including hospital LOS (11 vs 10 days) and 30-day mortality (3.6% vs 2.8%) were similar. During median 10 years follow-up, neo-aortic valve reoperation occurred in 4 BNPV (6%) vs 6 TNPV (3%) patients, with no statistically significant difference in time to reoperation. More BNPV patients had AR at discharge (4.9% vs 0%, p=0.014) and during follow-up (13.4% vs 4.3%, HR 3.9, p=0.004), with shorter time to first occurrence of AR (Figure 1A); this remained significant after adjusting for presence of VSD. Similarly, ARD was more common in BNPV (45% vs 37%, HR 1.64, p=0.02) with shorter time to first occurrence (Figure 1B).

 Conclusions:
 While patients with BNPV have similar short-term ASO outcomes, AR and ARD occur more frequently and earlier compared with TNPV patients. Further long-term studies are needed to determine whether this results in greater need for neo-aortic valve reoperation.


People are interested in the decision of social problems; therefore they are interested in social advertising development. However the spontaneous nature of its development, its swift registration in a professional way have generated a number of obstacles, which overcoming will make it possible to create an effective market of social advertising.


A list of 152 foraminif er al generic and subgeneric names proposed since the Loeblich and Tappan (1987) compilation along with pertinent bibliographic information is presented. In addition, 18 generic names not included in the above compilation are listed.


This poster discusses several possible approaches by which the nonlinear response of surficial soils can be explicitly modelled in physics-based ground motion simulations, focusing on the relative advantages and limitations of the various methodologies. These methods include fully-coupled 3D simulation models that directly allow soil nonlinearity in surficial soils, the domain reduction method for decomposing the physical domain into multiple subdomains for separate simulation, conventional site response analysis uncoupled from the simulations, and finally, the use of simple empiricallybased site amplification factors


Phase change materials (PCMs) have been widely used as efficient materials in latent heat thermal storage systems for various applications. The poor thermal conductivity of most organic PCMs, however, has long been considered as one of big obstacles hindering their practical applications. Here, we report the first example of in situ reduction of AgNO3 precursor by PEG for preparation of polyethylene glycol/silver nanoparticles (PEG/Ag) PCMs nanocomposites with enhanced thermal conductivity only though a simple blending and heating process, without using any complicated techniques. The prepared Ag nanoparticles show a well dispersion in PEG matrix and the Ag is mainly existed in a zero of valence status. As expected, a maximum value of 211.7 % of that of pure PEG in thermal conductivities of the resulting PEG/Ag PCMs were achieved. The latent heat for PEG/Ag PCMs nanocomposites were evaluated in the range from 121.9 J g−1 to 141.9 J g−1. Owing to high latent heat and excellent thermal conductivity, such PEG/Ag PCMs may have great potentials for energy saving applications. Especially, the in situ preparation of PEG/Ag makes it possible for site operation and scaled-up production, which is of great technologically significance for realization of PCMs into real applications.


A direct punching of inclined ultra-high strength steel sheets having low ductility was carried out to improve the quality of the sheared edge. In the direct punching of an inclined sheet, the contact between the sheet and punch became gradual because of touch from the bottom edge of the punch, and thus the sheared portion tended to bend in the latter half of punching. As the strength of the sheet increased, defects such as burr and secondary burnished surface were occurred around the sheared edge due to the low ductility. The range of direct punching for sheared edge without defects was shown for the high strength steel sheets. To prevent the occurrence of defects, a punch having inclined bottom was used. In this punch, the contact with the sheet was changed, the uniform contact with the inclined bottom was given. In the punch having the inclined bottom, the secondary burnished surface in the edge of 980 MPa grade steel sheet was prevented.


A method of the simulation of the waves was introduced,it simulated the phenomenon of wave's spread and interference of physics experiment during senior high school.Under the virtual reality exploitation technique flat OpenGL and programming environment of VC++,every particle that in reality can be abstract to a mathematical model.The system can control every particle's move orientation and speed,and confirm particle's location based on wave's characteristic of spread and interference and the modularization design idea.It is useful for student to understanding wave's theory and improving teaching effect.


II. More than 450 sites of the Stone Age, including 20 of the Early Paleolithic age, have been discovered in the territory of Mongolia during the last five years of investigation of the ancient lakes, hollows and the river systems of the Mongolian and Gobian Altai. The anciest sites are on the 90-, 100-, 120-, and 130-m terraces formed by the Miocene and Pliocene deposits overlain by the Eopleistocene alluvium. In 1985-87, about ten Early Paleolithic sites were discovered in the Baidrag-gol and Narijngol on the northern face of the Valley and Lake Hollow (Fig. 2). The striking and diverse material has been obtained at the locality in the Narijn-gol River Valley. The anciest camp-site was on the 120-, 130-m terrace, in 10-12km from the modern current of the river. The technique of splitting stone at the examined locality, is represented by nuclei, flakes and rarely the large lamellar flakes (Figs. 3 and 4). The most typical nuclei are those with the extremely low degree of treatment their strikingplatforms. The flakes of the citron type were chipped off just from the pebble surface. The set of tools is rather scanty: choppers, choppings, screbloes, pointed tools and flakes with crude retouch. The working surfaces are greatly deflated and practically do not differ from the pebble crust, as a result of the chemical and physical weathering. Undoubtedly, the earliest complexes of the type preceed those of the Levalloiso-Mousterian sites. The character of their primary and secondary treatments of artifacts allow to refer them to the Early Acheulean and even preAcheulean Periods. Thus, as far back as in the Early Paleolithic Epoch, Central Asia and Southern Siberia (in part) were peopled by the anciest population of the human beings.


Introduction: Social interaction is an inevitable technique and resource of children's mental development, and children learn how to interact with others. The purpose of this study was to determine the effectiveness of social skills training on aggression and impulsive among kindergartens children in Tehran in 2017-2018.
Materials & Methods: The study was a quasi-experimental design with a pre-test and post-test were selected by simple random sampling to compare a group of experiments (N= 7) with control (N = 7) groups. In this study, the statistical population in Tehran kindergartens in 2017-18 consisted of all children aged 4 to 6 years.  The intervention was conducted 10 sessions in 60-minute after pre-test and then the results were evaluated in two stages of pre-test and post-test by Matson's Social Skills Questionnaire and finally, after about one month the data were collected. Data were analyzed by using SPSSver.22 software.
 Results: According to the descriptive findings, the age range of 4 to 6 years with mean age of 5.5 years. The mean and SD scores of aggression and impulsive behaviors in the experimental and the control group were 24.14± 6.24 and 26.17±8.11, respectively. The mean scores of aggression and impulsive behaviors in the experimental group increased from 26.71 to 28.17 in the post-test. The standard deviation of these scores is 6.47 and 7.54, respectively. So that, the test did not show a significant difference at a level of p< 0.05.
Conclusion: Considering the use of social skills training interventions, it did not show a significant difference between aggression and impulsive in kindergartens children. Therefore, it is necessary to teach methods along with other psychotherapeutic to reduce aggression and impulsive behaviors among kindergartens children.


According to the processing and control requirements of precision CNC internal grinder, a design of ARM-based embedded precision CNC internal grinder soft-PLC system was proposed. The design idea of open CNC system was introduced and the system hardware and software were packaged as the components to develop the PLC applications, achieved the logic control of the machine tool. This design meets the requirements of software design instead of hardware design and system integration development of embedded CNC system, achieved the real-time process control and improved the precision.


For adults, developing a stable romantic relationship is often a fundamental life goal, and plays an important role in life satisfaction and overall wellbeing. Conflict is inevitable within ongoing couple relationships, and if not handled appropriately may have lasting negative effects. Hence the purpose of the current study was to examine the impact of attachment insecurities (attachment anxiety and attachment avoidance) on reports of conflict behaviours. Specifically, the research examined the direct associations of attachment anxiety and avoidance with the conflict behaviours of attack, avoidance and problem-solving, together with the indirect (mediating) role of negative partner attributions and the moderating role of relationship quality. Participants (N = 333) completed an online survey in which measures of attachment and relationship quality focused on participants' current relationship, but items assessing attributions and conflict behaviours were rated with reference to a standardized vignette depicting couple conflict. It was expected that attachment anxiety and avoidance would be associated positively with maladaptive conflict behaviours and negatively with problem-solving. Further, causal and responsibility attributions were expected to mediate the relationships between attachment dimensions and conflict behaviours. As predicted, attachment anxiety was associated positively with attack and negatively with problem-solving, while attachment avoidance predicted conflict avoidance. Attributions acted as a mediator between attachment anxiety and both attacking behaviour and problem-solving, but relationship quality did not moderate the links between attachment insecurities and maladaptive conflict behaviours. This research highlights the important role attributions play in the robust relationship between attachment dimensions and conflict behaviours. Theoretical and practical implications of the research are discussed


ABSTRACT Concentrically braced steel frames (CBSF) always suffer from weak-story failure with a large inter-story drift concentrated on the weakest story. A novel system of Energy-Dissipative Column (EDC) is proposed in this paper to improve the seismic behavior of low and mid-rise CBSFs. The EDC system consists of dual hinge supported steel boundary branches and replaceable steel strip dampers between them. Nonlinear dynamic analyses are conducted on 3-story and 6-story benchmark CBSF buildings with and without EDCs. The effectiveness of EDCs with different stiffness ratios on mitigating the seismic responses of CBSFs under design based and maximum considered earthquakes are investigated. The results show that the presence of EDCs in an existing multi-story CBSF can not only dissipate seismic energy to reduce the maximum inter-story drift, but facilitate more uniform inter-story drift distribution by redistributing the seismic forces along the structural height. It is found that the maximum inter-story drift and drift concentration can be reduced by half when the lateral stiffness ratio of EDC to CBSF reaches 0.2.


The behaviour of grafted polymer brushes subjected to shear forces is discussed along the lines of a model recently proposed by Rabin and Alexander. The model is shown to predict an increase in the layer height when a shear force is applied. The theory is tentatively applied to the interpretation of recent experimental results.


We develop a method for finding the economic sampling plan that minimizes expected total costs, subject to a constraint on labour time. We explicitly recognize the labour time required for sampling, investigation, extra processing effort per unit due to operating the process out of control, and the time to put the process back into control. These times, as well as the total production time, are frequently constrained by total available labour. With this constraint, we use a Lagrangian relaxation method to find the best sampling plan. Results of a numerical experiment show that the labour-constrained sampling plans and costs can differ substantially from the unconstrained solution. However, much of the cost penalty when labour is tightly constrained can be reduced with relatively small increases in total available labour time.


Abstract. In this paper, we study the zero dissipation limit problem for the Navier-Stokes equations of one-dimensional compressible viscous heat-conducting fluids. We prove that if the solution of the inviscid Euler equations is piecewise smooth with finitely many noninteracting shocks satisfying the entropy condition, then there exist solutions to Navier-Stokes equations which converge to the inviscid solution away from shock discontinuities at a rate of ε as the viscosity ε tend to zero, provided that the heat-conducting coefficient k = O(ε).


Every little helps with cutbacks and budget restraints being a part of modern life in the care industry. Yen-Pei Chen describes how managers can maximise their tax deductions while refurbishing a home, helping stretch their budgets that little bit further


SUNY Press, 2003). 13. CLR James, A History of Pan-African Revolt (New York: PM Press, 2012), 131. 14. Andrea Smith, 'Heteropatriarchy and the Three Pillars of White Supremacy: Rethinking Women of Color Organizing', in The Color of Violence: The INCITE! Anthology, ed. INCITE! Women of Color Against Violence (Boston, MA: South End Press, 2006). 15. See Wolfe, Settler Colonialism and the Transformation of Anthropology (1998), 1–2. Lorenzo Veracini, for his part, helpfully includes African settler colonies in his theoretical overview of this specific form of domination, and even points toward a provocative contextualization of the engineered failures of African decolonization in the context of settler colonialism on that continent in Lorenzo Veracini, Settler Colonialism: A Theoretical Overview (New York: Palgrave Macmillan, 2010), 106–7. 16. Alongside Fanon, one could point to the aforementioned James, Nyerere, Ali A. Mazrui, and perhaps most centrally, Ngugi Wa-Thiongo. The latter's first novel, Weep Not, Child, for instance, is a rich reflection on some of the central psychoaffective, territorial, cultural, and political predicaments into which Indigenous populations are forced by settler colonial structures of governance. Wa-Thiongo's influence on contemporary theories of Indigenous resurgence and struggle against settler colonial governance can be observed in such classic works in Native studies as Linda Tuhiwai-Smith's Decolonizing Methodologies, for instance. See Ngugi Wa-Thiongo, Weep Not, Child (New York: Penguin Classics, 2012); Linda Tuhiwai-Smith, Decolonizing Methodologies: Research and Indigenous Peoples (London: Zed Books, 2012). 17. On the imperative to reciprocate studies and politics for Africa when conducting studies of the politics in and of Africa, see Olufemi Taiwomignolo, 'What is African Studies?', Reclaiming the Human Sciences through African Perspectives Volume II, eds. Helen Lauer and Kofi Anyidoho (Accra, Ghana: Sub Saharan, 2012). 18. Siba N. Grovogui, 'Regimes of Sovereignty: Rethinking International Morality and the African Condition', The European Journal of International Relations 8 (2002); Achille Mbembe, 'At the Edge of the World: Boundaries, Territoriality, and Sovereignty in Africa', Public Culture 12 (2000). 19. See Roderick A. Ferguson, The Reorder of Things: The University and Its Pedagogies of Minority Difference (Minneapolis: University of Minnesota Press, 2012); Siba N. Grovogui, 'Deferring Difference', in Postcolonial Theory and International Relations, ed. Sanjay Seth (London: Routledge, 2012), 106–23; Gayatri Chakravorty Spivak, Death of a Discipline (New York: Columbia UP, 2003). 20. See, for example, John Borneman, 'American Anthropology as Foreign Policy', American Anthropologist 97 (1995); Marc Pinkoski, 'Back to Boas', Histories of Anthropology Annual 7 (2011): 127–69; George Stocking, 'Franz Boas and the Culture Concept in Historical Perspective', American Anthropologist 68 (1966): 867–82; Wolfe, Settler Colonialism and the Transformation of Anthropology (1998). 21. Frantz Fanon, Black Skin, White Masks (New York: Grove Press, 2008), 1–2. 22. Ibid., 18–19. 23. Bhabha, The Location of Culture, 57–93. 24. See Frantz Fanon, The Wretched of the Earth (New York: Grove, 2004); Frantz Fanon, 'Medicine and Colonialism', A Dying Colonialism (New York: Grove, 1965), 121–45. 25. Pinkoski, 'Back to Boas'.


Do metaphors influence our information policy preferences? Professor Osenga thinks so, which makes it especially important to choose the right one, as a metaphor is often the primary tool the general public uses to understand information policy. Using a five-point rubric, she evaluates, among others, understanding the Internet as "tubes," "highway," "space (cyberspace)," "coffee shop/bar" and "cloud." Osenga finds them all lacking in important ways. However, she believes the metaphor of the Internet as "ecosystem" is very promising and deserves to be further developed.


SUMMARY The determination of the curve traced in the phase-space by the solution of a Cauchy problem for a system of autonomous ordinary differential equations has been called trayectory problem. Formulae, analyses of the local truncation error using geometric elements and some numerical experiments of severa1 finite-difference methods for the numerical integration of trayectory problems are shown.


When analyzing the reliability of a time-constrained distributed software, the Markov state space is often used. However, many evaluation methods are not fast and the size of Markov state space is very large. In this paper, we propose an approach for the reliability analysis of distributed software with time constraint. The approach proposed is based on the principle of distributed program reliability analysis, and combines the reliability-preserving reduction with breath-first manner and fast reliability evaluation algorithm (FREA). We propose a new analysis model, called Reliability Analysis with Degree-n and Redundancy Reduction (RADR), and calculate transmission time of data files needed in the file spanning tree (FST). A simple distributed timeconstrained system is discussed to illustrate the feasibility of the proposed approach. Key-Words: Reliability analysis, Distributed software, File spanning tree, Time-constrained distributed software, Response time, Transmission time


Wireless Sensor Network (WSN) consists of tiny sensing devices which co-operate and communicate with each other to perform certain tasks. These are generally deployed in hostile environment where an adversary may capture nodes, replicate them and use it for its own purpose. If the clone nodes remain undetected, it can disrupt the network functions making it vulnerable to attacks. Hence false data can be injected or the legitimate data can be taken out. Thus to detect the clone nodes is the fundamental problem in WSN. The objective of distributed node clone detection is to detect clone nodes with minimum communication and storage overhead. The proposed project is a node clone detection system for sensor networks, which will be capable of detecting the node clone attack in a distributed way.


Abstract: Mobile Ad hoc Network is a network in which numerous are contained. These nodes are dynamic in nature and utilize multi-hop communication for communicating with one another. There isn't any central controller included in such a network. These nodes have random mobility and they are allowed to move in any direction due to the infrastructure less quality of this network. DFCP is a routing algorithm using which a path can be established amid source and target. The link failure leads to mitigate the efficacy of this protocol whose enhancement is required for maintaining the QoS. This research work suggests the enhancement of DFCP algorithm to recover the path when the link is failed. NS2 is applied to deploy the suggested algorithm. The simulation outcomes exhibit that the suggested algorithm outperformed the traditional methods concerning higher throughput and lower packet loss.


Trade routes to Spain for the transportation of raw material and minerals are presented. They provided for all types of minerals, tools, food and goods arriving from all over the world to the Imperial Villa de Potosi. Also, topics related to the Intangible Heritage (festivals and other entertainment, local foods, and worshiped virgins and Andean "deities") are handled.


The invention discloses a process for machining pipe row holes. The process comprises the following steps of A, feeding, B, blanking, C, resetting and D, discharging. Equipment for machining the pipe row holes comprises a punching machine, the punching machine comprises a base, a punching block and a power part for driving the punching block to vertically move, and a punching mold is arranged on the punching machine. A base block is fixed to the base, and a sleeve rod is fixed to the base block. A transverse through hole and a longitudinal hole communicating with the transverse through hole are formed in the sleeve rod. The size and position of the transverse through hole are matched with those of a blanking hole in the punching mold. The sleeve rod is arranged in a round hole in the punching mold in a clearance fit manner and located in the center of the round hole. The top face of a first supporting plate on the punching mold is fixed to the punching block, and the bottom face of a second supporting plate on the punching mold is fixed to the base. Communicating channels are formed in the base, the second supporting plate and a first fixing block on the punching mold in the longitudinal direction, the tops of the channels communicate with the longitudinal hole, and the bottoms of the channels communicate with the outside. The process and equipment for machining the pipe row holes are high in pipe punching efficiency and good in precision.


Abstract Objectives Given the recent debate challenging the contribution of cytology in cervical screening, we evaluated results of liquid-based cytology (LBC) and human papillomavirus (HPV) testing in cotesting preceding cervical cancer (CxCa) and precancer diagnoses in a national, heterogeneous population. Methods We assessed the results of cotesting, performed by Quest Diagnostics, in 13,633,071 women 30 years and older, tested 2010 to 2018. Cotest results preceding CxCa or precancer diagnoses were analyzed and stratified by histopathology. Results Among all screening results, 1,615 cotests preceded 1,259 CxCa diagnoses, and 11,164 cotests preceded 8,048 cervical precancer diagnoses. More women who were subsequently diagnosed with CxCa within 1 year were identified by the LBC result than by the HPV result (85.1%, 1,015/1,193 vs 77.5%, 925/1,193). Among all women with CxCa, the overall rate of nondetection was 13.1% (212/1,615) for cotesting results (LBC negative/HPV negative) and this rate increased substantially when testing exceeded 12 months compared to within 1 year prediagnosis of either CxCa or precancer. Conclusions Analysis of 9-year cotest results from a national reference laboratory confirms the value of LBC element in cotesting. This supports that LBC/HPV cotesting enhances screening for the identification of CxCa in women 30 years and older, more so than LBC or HPV alone within cotesting.


The rates of self-exchange electron transfer in the trimethylphosphine complex of cytochrome c have been measured by an NMR technique over a large range of ionic strengths. The rate constant is 1.56 x 10(4) M(-)(1) s(-)(1) at 23 degrees C (&mgr; = 0.34 M) at pH 6.9. Dependence on ionic strength of the rate constant is treated by van Leeuwen theory. Extrapolation of the rate constant to infinite ionic strength gives a rate constant of 3.9 x 10(5) M(-)(1) s(-)(1). This rate constant is compared with others reported for myoglobin and cytochrome b(5)(). The values for these systems range over 2 orders of magnitude with myoglobin-PMe(3) << cytochrome b(5)() < cytochrome c-PMe(3) < cytochrome c. Analysis of the data in terms of Marcus theory gives a reorganization energy, lambda, for self-exchange of 0.75 eV mol(-)(1) for cytochrome c-PMe(3). Substitution of Met-80 by PMe(3) appears to influence only weakly the rearrangement barrier to electron transfer.


would justify on that ground spending money on vocational training for general practice, on Briggs training for nurses, and on training social workers and following through the Merrison recommendations on postgraduate training." Extending skills meant, for instance, seeing that GPs were involved in community hospitals-a very important aspect of using skills in a different way. How much of the consultants' work could be taken over by non-medical staff was less certain. If North American experience suggested that surgical procedures could be performed to a high standard by technicians then there was no reason why the same should not be done here. There were many procedures done by doctors that could be done by non-medical staff: there was no legal bar to a surgeon who wished to organise his team so that technical operative procedures were carried out by non-medical assistants. Of course, said Dr Owen, the moment he made comments of that kind someone always came along to say they had made the necessary changes years before. "I am only too aware," he explained, "that if we could universalise the best practice in the NHS overnight we would solve practically all our problemsalmost everything that needs to be done in the NHS is being done in some localities-and if we could generalise the best standards our difficulties would disappear."


The effects on performance of the value of detecting a signal, the cost of a miss or false detection, and the size of the set from which the signals were drawn were studied in an auditory vigilance task. Seventy-two subjects were randomly assigned to each cell of a factorial arrangement of the cost and load variables and required to detect and identify each of several 49 db SPL pure tones differing only in frequency. Analyses of the number of correct detections, correct identifications, false detections and detection response time indicated a significant performance decrement with time for all measures and suggested that increasing costs for misses and false detections led to poorer detection performance while value had no effect. Load effected only identification performance, as higher loads led to a decrease in the percentage of signals correctly identified. The ď and β statistics of signal detection theory, indicated sensitivity to be invariant with manipulations of costs and with time. These findings imply that the performance decrement during a vigil is due to an increased strictness in the criterion the subject sets for deciding whether or not a signal was present. The cost factors were effective in manipulating performance by causing changes in the subjects' decision criteria.


Recent years we can hear a lot about cooperative decision-making, group or collaborative decision-making. These types of decisions are the consequences of developed working conditions: geographical dispersion, team working, and concurrent working. In the article we present two research works concerning two different collective decision situations: face-to-face decision-making and synchronous distributed decision-making. These two research studies adopt different approaches in order to support decision-making process, in view to different research objectives. Nevertheless, the conclusions show complementary aspect of these two studies.


th AIAAASM Thermophysics and Heat Transfer Conference June San Francisco CADSMCSimulationsofAp olloCapsuleAero dynamicsforHyp ersonicRareedConditionsJamesNMossyChristopherEGlassandFrancis AGreenezNASALangleyResearchCenterHamptonVADirect simulation Monte Carlo DSMC simulationsare p erformed for the Ap ollo capsule in the hyp ersonic lowdensity transitional ow regimeThe fo cus is on ow conditionssimilartothatexp eriencedbytheAp olloCommandMo duleduringhighaltitudep ortionofitsreentryResultsforaero dynamicforcesandmomentsarepresentedthatdemonstrate theirsensitivitytorarefactionthat is for free molecularcontinuum conditionsAlso aero dynamicdataarepresentedthatshowstheirsensitivitytoarangeofreentry velo city encompasing conditionsthat include reentry from low Earth orbit lunarreturn and Mars returnvelo cities to kmsThe rareed resultsare anchored inthe continuum regime with data from NavierStokes simulationsNomenclatureArefreference areaDb mcgcenter of gravitymcpcenter of pressuremCAaxial force co ecient Axial Force VArefCDdrag force co ecient Drag VArefCLlift force co ecient Lift VArefCmcgpitching moment co ecient Moment ab out center of gravity VArefDbCmpitching moment co ecient Moment ab out z VArefDbCNnormal force co ecient Normal Force VArefDbmaximum b o dy diameter mKnD H Sfree stream hard shp ere Knudsen numb erDbLlift force NLDlift to drag ratiomcsmean collision separation distance mmfpmean free path mnumb er densitymRaafterb o dy spherical nose radius mRnblunt foreb o dy spherical nose radius mRsshoulder radius mTtemp erature KVfree stream velo citymsxyzmo del co ordinates mXmole fractionsangle of incidence degSenior Research Engineer Aerothermo dynamics Branch Mail Stop A jnmosslarcnasagovFellow AIAAySenior Research Engineer Aerothermo dynamics Branch Mail Stop A ceglasslarcnasagov AIAA Senior Memb erzSenior Research Engineer Aerothermo dynamics Branch Mail Stop A fagreenelarcnasagov AIAA Senior MemberCopyrightc by the American Institute of Aeronautics and Astronautics Inc The US Governmenthas a royaltyfreelicense to exercise all rights under the copyright claimed herein for Governmental purp oses All other rights are reserved bythecopyrightowner of American Institute of Aeronautics and Astronautics Pap er


The majority of chronic diseases are likely to be the result of the combination of environmental exposures and human genetics. The exposome concept was proposed to increase our knowledge regarding the potential role of environment in the causation of disease. The exposome is a paradigm involving the study of all environmental exposures (e.g., air pollutants, chemical contaminants, diet or life style factors) and associated biological responses from conception until death. Once environmental exposures enter the human body they and their biological consequences become part of the internal exposome, which can be measured by OMICS technologies. Investigating perturbations in the internal exposome can provide information on direct measures of exposure or on physiological perturbations that are indicative of a certain exposure. Studying the internal exposome can provide biological underpinnings for empirically observed exposure-disease associations. In this thesis, we focused on air pollution, a high priority environmental pollutant responsible for 7 million premature deaths worldwide each year. Air pollution is recognized as a human carcinogen associated with lung cancer. It is also a major risk factor for other acute and chronic diseases including cardiovascular disease and chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease. The overall aim of this thesis is to study three OMICS platforms (proteomics, transcriptomics, and DNA-methylomics) in relation to exposure to air pollution in order to have a better understanding of the biological processes that link air pollution exposure to health effects. When successful such analyses might contribute to generating insights on air pollution induced health effects, identifying air pollutant specific biological pathways, and detecting biomarkers of early disease.


A new approach to 2-amino-6-(methoxycarbonyl)amino-4-(1,2,3,6-tetrahydro-1-pyridyl)pyrimidine 1-oxide (3) is described. Methyl [1-ethoxy-2-(ethoxycarbonyl)-ethylidene]carbamate (5) reacted with guanidine to the pyrimidinecarbamate 6, which was successively transformed into methyl 2-amino-6-(p-tolyslulfonyl)oxy-4-pyrimidinecarbamate (8). Oxidation of 8 led to the corresponding pyrimidine N-oxide 9, a useful starting material to 3.


B ecause statins markedly reduce cardiovascular risk, poor persistence with them is an important clinical problem. If statins were stopped for valid reasons, there may be no opportunity for improvement. However, there are many invalid reasons why patients stop medication, often for symptoms that, although not causally related, are listed in package inserts. Physicians also stop statin therapy for invalid reasons. Several consensus statements, from the Canadian Cardiology Society, the European Atherosclerosis Society, and the National Lipid Association, have reviewed aspects of the adverse effects of statins from various perspectives. In this narrative review, we discuss approaches to helping patients continue needed therapy with statins, based on experience with >50 000 patients attending our vascular prevention clinics over many years and from the perspective of clinical pharmacology, including pharmacokinetic and pharmacogenomic factors that impair persistence by worsening causally related effects of statins.


Abstract Here we model the pathways leading to the introduction of highly pathogenic avian influenza (HPAI) of the H5N1 subtype to Ethiopia through the legal import of day-old-chicks (DOC). The uncertainties, variability and randomness associated with the model inputs and final probabilities were implemented using Monte Carlo simulation (@Risk; Palisade Corp.). Our results suggest that under current conditions the risk of introducing virus through the legal trade of DOC is very low but is likely to occur. Furthermore, we would expect to import infection every 3.8 years (90%CI: 0.30-235) from the approved third countries considered (i.e. Egypt, Saudi Arabia, United Kingdom and the Netherlands) with an annual probability of importing at least one infected DOC of 23% (90%CI: 0.4%-96%). The number of parent stock testing positive at the countries of origin of the DOC is suggested to have the highest effect on both risk estimates (r=). Our simulations also suggest that the higher the level of poor compliance of the veterinary authorities at the border inspection posts (BIP) the lower the number of years between virus introductions in Ethiopia (r=). We report and discuss the impact of sensitivity analysis of the baseline assumptions on the uncertainty associated with both estimates of risk. Keywords: Highly Pathogenic Avian Influenza H5N1, quantitative risk assessment, import of day-old-chicks, epidemiology


The invention discloses a medetomidine industrial splitting method which takes L-(-) camphorsulfonic acid as a chiral reagent and C1-C5 alcohol as a chiral auxiliary. According to the method disclosed by the invention, the splitting yield reaches up to over 40% and the splitting optical purity reaches over 99.5%. The method is simple in industrialized operation and can be used for industrialized and commercialized production.


TECHNICAL GRADUATE. Nine years' experience as resident, plant and general electrical engineer. Desires position with established company ase stimator, contractor's follow-up man, installation road representative, or salesman along engineering lines in the metropolitan district. E-4154.


Based on Landsat7 Enhanced Thematic Mapper Plus(ETM+) image data,the information of mudflats of Weishanhu Lake area was extracted,by using of established classification model method with spectral characteristics and gray level concurrence matrix texture feature of typical types.In addition,random sampling method was evaluated on the classifications with an overall accuracy(Kappa Coefficient) of 0.8227.The results show that spectral features classification method which is single used can't effectively separate the information of mudflats from wetland.While it is combined with the texture feature classification method,it could separate them well and achieve a certain classification accuracy.So it provides a method for the extraction of remote sensing information.


Due to the influence of various social and environmental factors, the incidence of infertility is increasing, and the application of assisted reproductive technology (ART) is becoming more and more wide-spread. At present, the clinical pregnancy rate ofinvitrofertilization (IVF) is 40%~60%, and decreased endometrial receptivity is one of the reasons for implantation failure. Endometrial receptivity refers to the capacity of the endometrium to accept embryos. Intrauterine adhesions (IUA), also known as Asherman syndrome (AS), is one of the most common causes of decreased endometrial receptivity after intrauterine surgery or inflammation. At present, most experts believe that IUA should be defined as intrauterine adhesion or fibrosis, which is accompanied by one or more of the following clinical symptoms: menstrual reduction, amenorrhea


In terms of reflecting the period when Ahmet Midhat Efendi lived and penned his works, the novel Felâtun Beyle Rakim Efendi is the most important work of him, the one that set off the highest reaction and was mentioned most often later on. Through two characters opposite to each other in his novel, Ahmet Midhat Efendi presented to the public opinion the troubles in the early periods of the Ottoman modernization and also solutions to those troubles. The character Felâtun Bey who was introduced as a negative model created by modernization was criticized ruthlessly by the author to give a message to the society and define that particular period. However, Felâtun Bey and the understanding of "European manners" he represented were not confined to the civil sphere or space. Besides, the environment of  Doc. Dr., Istanbul Universitesi Edebiyat Fakultesi Turk Dili ve Edebiyati Bolumu Ali Şukru CORUK/ Turk Dili ve Edebiyati Dergisi Cilt/Sayi: XLVII 66 which Felâtun Bey was a representative did not occur spontaneously, but appeared as a reflection of the life style of the courtiers and high rank-officials upon society, who personally considered modernization as the sole way of salvation. Hence, in 1875, a short while after the novel was written, the state which had focused on the image of modernization and got into huge debts for this cause would go bankrupt just like Felâtun Bey. In this paper, correspondences between the modernization experiences of Felâtun Bey and of the Ottoman State will be discussed with reference to the events and people in history.


Introduction The use of the long-wavelength-band (Lband) is attractive for both increasing the capacity of wavelength division multiplexing (WDM) systems and has been used in WDM transmission experiments at over 1 Tb/s. Recently, a gain bandwidth of about 80nm has been achieved by integrating the L-band EDFA in parallel with conventional band (Cband) EDFA [1]. Moreover, the L-band EDFAs will make it possible to construct an effective WDM systems employing dispersion-shifted fiber (DSF) without the degradation caused by four-wave-mixing (FWM) [2]. The L-band erbium-doped fiber amplifier (EDFA) is studied because it can be constructed by silica-based erbium-doped fiber (EDF) and has a low linearity for WDM signals. However, L-band EDFAs have a low power conversion efficiency (PCE) compared to a C-band. Therefore, a double-pass L-band EDFA has been introduced to enhance the gain in this region [3]. Besides gain improvement, L-band EDFAs for WDM system must also be able to manage gain variation due to dynamic add/drop or abrupt failure in the system. To stabilize the gain, various techniques applying the ring laser have been investigated for single-pass EDFA [4-5]. In this letter, a novel and simple configuration of gain-clamped double-pass Lband EDFA is proposed and demonstrated using a ring resonator.


LIVER INVOLVEMENT can be demonstrated in about 25% of cases of cystic fibrosis by careful clinical and autopsy evaluation, although jaundice is rare and hepatic function studies are usually normal. 1 A characteristic biliary cirrhosis with concretions becomes more common as age increases; sometimes this causes portal hypertension, requiring a shunt operation. 1,2 In neonates with cystic fibrosis liver disease is not usually clinically apparent. Gross and microscopic abnormalities of the liver, the biliary tree, 3 and the gallbladder 4 have been described, but only a few instances of prolonged neonatal obstructive jaundice have been reported. 2,5-7 This report describes a case of prolonged obstructive jaundice in a newborn with meconium ileus and jejunal atresia. Liver biopsy during a second operation for intestinal obstruction at 12 weeks of age showed regressing liver pathology at a time when liver disease had become clinically inapparent. Report of a Case This infant (#1354593)


It is shown that any two bivariate polynomials can be made linearly disjoint by applying a linear transformation to one of the variables in one of the polynomials. From this it is deduced that the algebraic fundamental group of an affine line is closed relative to direct products.


The realization method of the basic automation control system of No.1 Sin-tering Plant of Maanshan Iron Steel Co was introduced,including hardware,software com-position and network configuration of the system.This project had completed the integrated reconstruction of electric control and instrument control of No.1,No.2 and No.3 shaft fur-naces.PID control method was combined with hand control in the system,which solved well the regulation problem of gas flow rate.The practice showed that the system control had bet-ter effect.


The explicit form of the effective potential is found in the two-loop approximation in the Johnson-Baker-Willey (JBW) electrodynamics and the Cornwall-Norton (CN) model. The character of the breaking of scale and chiral invariance in the JBW electrodynamics is investigated, and also that of scale, chiral, and tau/sub 2/ invariance in the CN model. The symmetry breaking in these models, despite its dynamic character (the bare masses of all particles are equal to zero) is not spontaneous, but explicit: The currents corresponding to these symmetries are not conserved.


The literary Sketches of Yue Wei Cao Tang is a book about anecdotes.Judging from the methodology,the literary sketches reflect the author's ideas about pragmatism and moralization,the contradiction between political ethics and academic conception.However,the author's thought is a combination of Han school and Song school,practice and metaphysics,emotion and politesse.Such could be found in the composition,as quality of verity has been promoted from "positive wrong" to "passive right" with pragmatism impact fading gradually.


A proportion of patients with interstitial lung diseases (ILDs) are at risk of developing a progressive-fibrosing phenotype, which is associated with a deterioration in lung function and early mortality. In addition to idiopathic pulmonary fibrosis (IPF), fibrosing ILDs that may present a progressive phenotype include idiopathic nonspecific interstitial pneumonia, connective tissue disease-associated ILDs, hypersensitivity pneumonitis, unclassifiable idiopathic interstitial pneumonia, ILDs related to other occupational exposures and sarcoidosis. Corticosteroids and/or immunosuppressive therapies are sometimes prescribed to patients with these diseases. However, this treatment regimen may not be effective, adequate on its own or well tolerated, suggesting that there is a pressing need for efficacious and better tolerated therapies. Currently, the only approved treatments to slow disease progression in patients with IPF are nintedanib and pirfenidone. Similarities in pathobiological mechanisms leading to fibrosis between IPF and other ILDs that may present a progressive-fibrosing phenotype provide a rationale to suggest that nintedanib and pirfenidone may be therapeutic options for patients with the latter diseases. This review provides an overview of the therapeutic options currently available for patients with fibrosing ILDs, including fibrosing ILDs that may present a progressive phenotype, and explores the status of the randomised controlled trials that are underway to determine the efficacy and safety of nintedanib and pirfenidone. Aside from IPF, there are no proven therapies for other ILDs with a progressive-fibrosing phenotype that are effective and have tolerable adverse effects. Clinical studies evaluating the benefits of antifibrotic therapy in these populations are underway. http://ow.ly/40yL30mOs0q


A lot of time and resources have been devoted to research in rangeland hydrology over the past 40 years. What have we learned? Natural variability in precipitation and rangeland watershed characteristics necessitate the results be applicable over both spatial and temporal scales. This requires that data be collected over a sufficient area and time span to evaluate not only the normal storm event but maybe more importantly, the extreme (large) events. While there have been some changes in the research approaches of the past 40 years many of the present concepts in rangeland and watershed hydrology have not changed since the 1970s. Are these approaches still valid? There has been very little effort directed toward developing new understanding of the processes, which make up the hydrologic phenomena on rangelands. New principles must be developed from rangeland settings, not adaptations from cultivated agricultural or forested watersheds.


Differential gene expression profiling of pediatric common acute lymphoblastic leukemia (cALL) versus non-malignant tissues enables identification of aberrantly expressed genes in malignant cells, facilitating discrimination of leukemic from normal cells and possibly revealing specific disease mechanisms. Expression patterns of 29 pediatric cALL samples were analyzed by use of high-density DNA microarrays HG-U133A. Leukemic patients' bone marrow samples were compared to sorted B cells from cord blood of healthy donors expressing CD19 and CD10 surface antigens. Principal component analysis clearly distinguished leukemia samples from normal controls. Significance analysis of microarrays revealed 723 genes significantly up-regulated, and 617 down-regulated genes in leukemic cells. Independent validation of deregulated genes by RT-PCR was chosen to address enrichment limitations of controls. A comparison to previous publications investigating genetically defined subsets of cALL revealed only 5 – 22% match with our differentially expressed genes. Furthermore, class prediction with only 14 differentially expressed genes correctly classified tumors and controls not included in the training set and hitherto not investigated samples including 3 leukemic tumor lines (NALM-6, CALL-2, 697) as cALL. Interestingly, terminal deoxynucleotidyl-transferase (DNTT) as well as in the context of cALL unknown genes, were found to be the strongest predictive genes for the malignant phenotype signifying the diagnostic value of our approach.


Quantum principal component analysis is a dimensionality reduction method to select the significant features of a dataset. A classical method finds the solution in polynomial time, but when the dimension of feature space scales exponentially, it is inefficient to compute the matrix exponentiation of the covariance matrix. The quantum method uses density matrix exponentiation to find principal components with exponential speedup. We enhance the existing algorithm that applies amplitude amplification using range-based static selection of eigenstates on the output of phase estimation. So, we propose an equivalent quantum method with the same complexity using a dynamic selection of eigenstates. Our algorithm can efficiently find phases of equally likely eigenvalues based on the similarity scores. It obtains principal components associated with highly probable larger eigenvalues. We analyze these methods on various factors to justify the resulting complexity of a proposed method as effective in quantum counterparts.


With the development of society, local area network have become larger and larger, in order to improve network performance and avoid the storm , strengthen network security, and the organizational structure of the consideration, in practical engineering need to consider the network division of vlan, and the division of vlan also blocked between different vlan network of mutual visits, the inconvenience brought about by the practical work, through the three layer switch technology can solve the different vlan communication problems.


The invention relates to a device for directional introduction of combustion air into the secondary air sole of a coke oven, which is formed by at least one collecting line for combustion air, which runs along below the coke oven chamber doors of coke ovens of a coke oven, said manifold having at least one branch in at least one coke oven chamber, through the combustion air for complete combustion of coking gas is introduced into the secondary air sole at least a coke oven, so that the combustion in the coke oven sole is optimized and thereby the Verkokungsverlauf is controllable. Preferably, each coke oven can be supplied individually with combustion air through corresponding actuators, so that each coke oven while the Verkokungsverlaufs individually supplied with combustion air, which is in view of the staggered Verkokungsverlaufs in coke oven chambers of a coke oven is of great advantage. The invention also relates to a method for the directed introduction of combustion air into the secondary air soles at least a coke oven of a coke oven.


shown in Fig. 1). In this communication, we describe fermentation, isolation, structure elucidation and antitumor activities of F390B, C and nidulalin A. Culture, AJ117292, was isolated from a soil sample collected at KanagawaPrefecture, Japan and the fungus, AJ117291 was isolated from a soil sample collected at Ehime Prefecture, Japan. Both of the strains were identified as Penicillium sp. by morphological characteristics, and AJ117292 was deposited at the National


Design and creation of wound coverings is a complex interdisciplinary process. Insight into physical and chemical properties and interaction patterns of macromolecular compounds ensure successful development of new medical devices. Article reviews wound dressings in terms of the physical chemistry of polymers. However, only a close collaboration between experts in such a specific field as medical devices the preparation of which requires special focus, with clinicians, could help develop new domestic products and save the market from substandard products.


under R.S.C., O. 14. Kerr L.J., dissenting, considered that these options were too favourable to the defendant. He proposed instead restitutio in integrum: retransfer of the shares to the plaintiff and repayment of the monies paid by the defendant. With respect, the approach of the majority is the correct one. The plaintiffs loss must be assessed in accordance with both the normal rules for contractual damages and the equitable rule in Rose v. Rose. He must be placed in the same position as if the agreement had been performed.


This week The Leader presents resolutions approved by delegates to the recent annual meeting of tlie Civil Service Employees Assn. that require administrative rather than legislative action to accomplish. Last week, resolutions which! r/<?6 r must be acted on in the State Legislature were reported. This week's list ends the resolutions report. RETIREMENT A-76—Show additional percentage payments made by the State on employees retirement annual report. A-77—Provide full option information and level rate option until eligible for Social Security. A-78—Re-open Social Security. B Y the time our readers receive this edition of The Leader tlie 1964 national and local election results will be ui und the effect of these results on civil service will have meaning for some time to com«. Public employees, unlike their counterparts in private industry, deal and negotiate with elected legislative bodies, not company owiittgers and presidents whose (Coiithiued ou Pafe 13) crea.sed one day per year for each two years of service after 15 years. A-80—All rights and privileges restored to new State employees. A-81—Equivalent time off for State workers for holidays which fall on Saturdays. A-82—Adequate uniform allowance for all State employees required to wear uniforms or other special work equipment on duty. A-83—Provide leave with full pay for all employees injured in line of duty, A-84—Provide compensatory time for time spent on business travel. A-85—Provide cash overtime to Public Works employees on stake-(Special To The Leader) ALBANY, Nov. 2—Following a meeting last week between the Civil Service Employees Assn. and the State Judicial Conference, a CSEA spokesman told The Leader that the Employees Association was preparing proposals to amend some facets of new Career Service Rules promulgated recently by the Conference. The rules apply to approximately 10,000 employees of the Unified Court System throughout the State. A second meeting, to be held shortly, will deal with problems of the Conference's classification survey covering New York City court employees. CSEA Wants Protection Assured At last week's meeting, held in New York City, the 60-page document outlining the rules and regulations were dealt with point by point. CSEA will solicit recommendations and comments from representatives of its members employed by the Unified Court System before submitting final The next rev,ular meeting of | Pi'oPosals on the rules to the Beverage Control Board official and field representative for the Civil Service Employees Assn., died recently in Allis, Wisconsin. He was 76. A State beverage control system …


The optimal control of voltage and reactive power is one of the essential issues for power grids' security and the economical operation. Having elaborated the model of reactive power optimization in regional power grids, this paper advances an improved genetic algorithm integrated with reduced gradient technique for solving of ORP problem in regional power networks. It is implemented repeatedly on IEEE 30-bus system and an actual regional power grid. Compared with several other algorithms, the testing results demonstrate its effectiveness. It is showed that the proposed hybrid algorithm can gain better voltage profile and less active power loss simultaneously within permissible limits.


This paper investigates the influence of the basis set on the GW self-energy correction in the full-potential linearized augmented-plane-wave (LAPW) approach and similar linearized all-electron methods. A systematic improvement is achieved by including local orbitals that are defined as second and higher energy derivatives of solutions to the radial scalar-relativistic Dirac equation and thus constitute a natural extension of the LAPW basis set. Within this approach linearization errors can be eliminated, and the basis set becomes complete. While the exchange contribution to the self-energy is little affected by the increased basis-set flexibility, the correlation contribution benefits from the better description of the unoccupied states, as do the quasiparticle energies. The resulting band gaps remain relatively unaffected, however; for Si we find an increase of 0.03 eV.


The purpose of this article is to identify issues of copyright protection for sports and robotics moves that requires an in-depth research and a definition of its specifics. The article justifies the need to study relevant issues such as pantomime and parody as elements of sports moves, modern sports and sports for people with disabilities, moves of emerging robots in terms of copyright, and stakeholders' awareness and willingness to commercialize copyright in the areas.


Dimension lumber, visually graded in accordance with the National Grading Rule and assigned design values derived in accordance with procedures found in ASTM D 1990, has provided satisfactory performance in homes and other structural applications for many years. This ongoing satisfactory performance depends upon a recognition that all standards are living documents that must change over time as new information becomes available. In fact, since its original approval in 1991, D 1990 has been revised to reflect knowledge gained and the changing needs of the wood products industry. These revisions include refinements to the Grade Quality Index provisions, adoption of guiding principles for the maintenance of design values, a framework for monitoring design values, and adoption of a method for deciding when a reassessment of design values is needed. In 2014, a revision to D 1990 was adopted that focused on standardizing the minimum requirements for monitoring, evaluating, and reassessing lumber properties developed in accordance with D 1990. This paper describes the simulation methods that were used to identify a statistical test that performs acceptably (as determined by the ASTM consensus ballot process) when applied to test data from a monitoring program to determine whether a re-evaluation of the current resource is needed.


The skew t (2df) distribution proposed by Azzalini (1985) is a useful model to describe the skewed data sets with heavy tails. Since the moments of this distribution do not exist, not much literature is available on it. Its study in this research is based on large populations using some selected values of the distribution's skew parameter. The impact of this parameter is determined on its shape characteristics, distribution function, quartiles and other measures including hazard curves and Shannon entropy. The estimators of the skew parameter by maximum likelihood estimation and moments are determined and their efficiencies investigated concerning Fisher information through simulation procedures drawing random samples of various sizes. In addition, for Bayesian analysis the skew parameter is assigned a uniform prior distribution over the range (a, 0) for a 0 and the impact of fixed values of z is ascertained on the relationship between posterior mean and z for selected values of a as well as that between the posterior mean and 'a' for selected values of z. The associated variances of the posterior distribution are also determined. The skew t distribution (2df) is applied to a data set consisting of 63 breaking strengths of fibreglass from Smith & Naylor, (1987) estimating lambda by the method of maximum likelihood and Moment Estimator.


OBJECTIVE
To evaluate the effect of arthrocentesis and sodium hyaluronate (SH) injections on nitrite, nitrate, and thiobarbituric acid-reactive substance (TBA-RS) levels in temporomandibular joint internal derangements.

STUDY DESIGN
Arthrocentesis was performed on 10 patients, and 15 patients received a supplemental injection of SH after arthrocentesis. All these patients received an SH injection 15 days after the first intervention. The synovial fluid samples were obtained before arthrocentesis on the first appointment and before the SH injection 15 days later. Nitrite and nitrate levels were measured with a highly sensitive and specific chemiluminescence detection method, and the concentration of lipid peroxidation products was assessed by means of the thiobarbituric acid reaction.

RESULTS
Symptomatic improvement was seen in both groups. Nitrite, nitrate, and TBA-RS levels only decreased significantly (P <.05) with a supplemental SH injection after arthrocentesis.

CONCLUSIONS
Intra-articular injections of SH may reduce nitrite, nitrate, and TBA-RS levels that play a role in the pathogenesis of various temporomandibular disorders.


Abstract The application of electrically shunted piezoceramic materials (PZTs) for increasing transmission loss is studied. A test setup in an SAE J1400 facility is used to analyze the sound transmission loss due to a test plate with shunted PZTs, and to compare the results with an undamped plate and a plate with constrained-layer damping materials. The test results indicate that shunted PZTs can increase sound transmission loss by approximately 6 dB for a pure tone input at 162 Hz, and 7 dB for a broad band input of 10–10000 Hz. The test results further show that, compared to the constrained layer damping materials that are commonly used in the automotive industry, PZTs provide a substantially higher sound transmission loss-to-weight ratio. This paper will present the test setup in an SAE J1400 facility, the installation of the PZTs on a test plate, and the tuning procedure that is used for the shunt circuits. It also provides a detailed analysis of the results of sound transmission tests for three different test plates, namely an undamped plate, a plate with constrained layer damping, and a plate with electrically shunted PZTs.


Background: The 2019 novel coronavirus disease (COVID-19) outbreak turned into a pandemic, with hundreds of thousands of cases reported globally. The number of cases dramatically increased beginning in early March 2020. Aim: We assessed the cumulative change in the incidence and case-fatality rates of COVID-19 at the global, regional, and national levels from January to March 16, 2020, in 154 affected countries and territories globally. Methods: We collected data of COVID-19 cases using the GitHub repository, which provided real-time surveillance information developed by the Center for Systems Science and Engineering (CSSE), Johns Hopkins University (USA). Information such as confirmed COVID-19 cases, deaths, and recoveries reported across all affected countries was collected from January 22 to March 16, 2020. We estimated the change in the incidence rate, case-fatality rate, and recovery rate from January 22 to February 29 and from March 1 to March 16, 2020. Results: From January 22 to March 16, 2020, globally, the number of incident COVID-19 cases increased by 276.2%, and Europe recorded 65,281 new cases from March 1 to 16, 2020. Overall, the case-fatality rate was 3.92%, with a high COVID-19 fatality rate in Italy (7.7%), Iran (5.7%), China (4.2%) and the United Kingdom (3.6%). The estimated percentage change in COVID-19 cases from March 1 to 16, 2020, was highest in Belgium (105.8/100,000 population), followed by Qatar (439/100,000 population) and Portugal (331/100,000 population). The overall recovery rate of COVID-19 was 43%; China (35.5%) had the highest recovery rate, while the United States of America recorded a recovery rate of 0.3%. Conclusion: Overall, all the COVID-19-affected countries showed an upward trend in incidence, with little change in the incidence rate of -0.20% from January to Mid-March. The case-fatality rate was found to be 3.92%, and the recovery rate was observed to be less than half (43%) among COVID-19 patients. Italy, Iran, and Spain had the largest numbers of new cases of COVID-19 from March 1 to 16, 2020.


Abstract This research uses survey data and count data of formal rules in a Dutch organization to investigate the relationships between an objective measure of formalization and subjective measures of formalization and red tape. We find that red tape perceptions are related to perceptions of formalization. Second, we find that perceived formalization is weakly, significantly related to objective measures of formalization but that objective formalization measures do not correspond to higher levels of red tape perceptions. We conclude that red tape and formalization are distinct concepts, but question the claim that formalization is a necessary condition for red tape.


(F) (G) (H) (I) (J) (A) (B) (C) (D) (E) (F) (G) (H) (I) (J) . The fiber orientation distribution (FOD) function was generated with 45 spherical harmonics (lmax=8) and was then reconstructed at 8000 equidistant points on the sphere, within each voxel. MBR Bootstrapping: In order to obtain residuals in a given voxel we spherically convolved the spherical harmonics of the FOD generated by CSD with the rotational harmonics of the response function. This gave us recovered HARDI signal, devoid of noise. Residuals were calculated by taking the difference between the recovered HARDI signal and the original HARDI signal. A new image set was created by randomly shuffling the residuals, for any given voxel, amongst all the diffusion-encoding directions and then adding them to the recovered HARDI signals. The image set created by each bootstrap sampling was then processed with CSD to generate new instances of the FODs. To further minimize the effects of noise we set a threshold to only accept those peaks on the FOD, as relating to the principle underlying intravoxel fiber orientations (one or more), whose magnitude was greater than 70% of the maximum peak magnitude on the FOD, in a given voxel. Probability of Number of Fiber Populations: The probability of observing n fiber orientations (n ∈ (1, 2, 3, >3)) was determined from the frequency of finding n fiber orientations over 100 MBR bootstrap iterations. Probability Distribution in Parcellated Regions: The median was calculated as the descriptor of the distribution of probabilities of n fiber orientations amongst all the voxels within each of the cortical and subcortical parcellated regions. In order to demonstrate inter-subject consistency we plotted the parcellation medians for one subject against each of the other subjects, and also plotted the group medians of the parcellation medians across all five subjects for the left hemisphere against the right to assess symmetry of cortical complexity. To obtain a statistical measure of inter-subject similarity we computed correlation coefficient matrices for the parcellation medians between all five subjects for each n and for cortical and subcortical regions separately. Results Various maps for a mid-volume coronal slice in one subject are shown in Figure 1. Fig. 1(A) shows an anisotropy map, followed by voxelwise maps of P(n = 1), P(n = 2), P(n = 3) and P(n > 3) (Fig. 1(B- E), respectively) over 100 MBR bootstrap iterations rendered with the same colormap scaled 0-100%. Color-rendered parcellation regions are overlaid on the corresponding contrast-reduced grayscale T1-weighted image in Fig. 1(F), which is followed by maps of the parcellation medians in this subject for P(n = 1), P(n = 2), P(n = 3) and P(n > 3) (Fig. 1(G-J), respectively) rendered with the same colormap but individually windowed to aid visualization for qualitative comparison. The plots in Fig. 2 have used different marker types and colors to separate cortical and subcortical parcellation regions and median probabilities for each n. The strong correspondence between group medians of parcellation medians in the left and right hemispheres is clearly evident in Fig. 2(A). The parcellation medians in the first subject also correspond well with the parcellation medians in the other four subjects (Fig. 2(B-E)). All of the off-diagonal entries in the matrices of correlation coefficients in Fig. 3 are statistically significant (p<0.01), with correlation coefficients being generally higher for subcortical parcellation regions (Fig. 2(A,C,E,G)) than cortical regions (Fig. 2(B,D,F,H)). Conclusion We have successfully shown consistency in the probability of finding different fiber configurations within parcellated cortical and subcortical regions both between hemispheres and amongst a small group of healthy subjects. This suggests that applying model-based residual bootstrapping to the CSD analysis of clinically- acquirable HARDI data can elucidate information about the underlying microstructural complexity. This information represents a non-invasive measure that is sensitive to cortical cytoarchitecture and that may be useful in cortical parcellation and in the identification of cortical lesions.


The present invention relates to a transparent rubber modified styrene series resin composition which comprises rubber particle disperse phase formed from rubber-like copolymer and copolymer continuous phase consisting of styrene series monomer, (methyl) acrylic ester series monomer, acrylonitrile series monomer and other monomer which can be copolymerized. By controlling the content of polystyrene block of rubber-like copolymer, ratio of rubber particles containing internal included particles and content ratio of molecular weight being 3000-50000 in the continuous phase it can make the resincomposite possess excellent resistance to chemicals and workability, at the same time it also can make its transparency and resistance to impact obtain equibalance.


While our understanding of the biological aspects of the treatment of Bipolar Affective Disorder (BAD) has grown exponentially over the last few decades, our grasp of the psychological aspects of treatment have not evolved as dramatically. Psychosocial factors may contribute 25–30% to the outcome variance of bipolar disorder [1] and despite optimal pharmacotherapy, up to 50% of sufferers may encounter further episodes [2]. In recent years, psychotherapies that are focal and structured have enjoyed increasing support in the management of a variety of psychiatric disorders, including severe mood disorder.


Permeable chemical protective suit is an important equipment in the nuclear,biological,chemical( NBC) warfare. The present state of the permeable chemical protective suit at home and abroad was described. New materials development for the permeable chemical protective suit was introduced. The trend of the permeable chemical protective suit was analyzed.


Gas chromatographic analysis of benzene extracts was used to study the effects of temperature and relative humidity on the degradation and volatilization of 2-chloro-2′,6′-diethyl-N-(methoxymethyl)acetanilide (alachlor) in the soil. The relative humidity of a closed system had little effect on alachlor retention in air dry Sawyer fine sandy loam at 22 C, but had a pronounced effect when soil temperature was 38 C or higher. At 0% relative humidity (38 C or 46 C) alachlor was degraded to 2-chloro-2′,6′-diethylacetanilide. Decomposition, which also occurred in 5 N aqueous HCl, was attributed to acidic soil water film surfaces. As relative humidity within the system increased, the rate of degradation decreased, apparently because condensation of water vapor increased the thickness of the soil water film and decreased the surface acidity. At 38 C, minimum loss was noted at 31% relative humidity, and at 46 C, minimum loss was found at 79% relative humidity. The increased loss of alachlor at relative humidities above these critical points was attributed to volatility and not to chemical degradation.


The scientific management and the people-oriented management are two paradigms of management theories,but both have inherent limitations as a product of subject-object thinking.Therefore,with the integration of the two kinds of management,a new paradigm-dialogue management is bound to come into existence.The dialogue management takes the scientific management as the base and people-oriented management as the value-oriented one to create a new inherent mechanism and complete pattern.It is internalized and surpassed the two,beyond the model of subject-object dualism.It is an inter-subjective management,suitable for the internal logic for development and has demonstrated its success at present.


This report is a bioinformatic analysis of samples from NCBI GEO database series GS132501. It includes previously un-reported data for miR-mimic over-expression of the miRNAs miR-18b, miR-155, miR-142-3p, and miR-890 in the ATCC CRL-1790 cell line. Data analysis was performed using Nanostring nSolver 4.0 and Advanced Analysis Module 2.0 plugin (Nanostring MAN-10030-03). Bioinformatic methods utilized include pathway scoring, differential expression (DE), and gene-set enrichment (GSE) analyses. Findings, with full supplementary data, provide a community resource for effects of dysregulation of these miRNAs in a colon 'epithelial-like' cell line.


The present study was performed to evaluate the effect of 28 days subchronic oral administration of AgNPs in normal and irradiated (4 Gy) rats on the distribution of certain trace elements (silver (Ag), zinc (Zn), copper (Cu), iron (Fe), calcium (Ca), magnesium (Mg) and manganese (Mn) contents in various organs tissues including liver, kidney, lung and testes. AgNPs were orally administered daily for 28 days continuously and the vehicle as well in the vehicle group. The study was performed to investigate the effect of AgNPs on trace elements in different organs and as compared with irradiated treated AgNPs group. Results of the present study demonstrated that subchronic oral administration of AgNPs (26.878 mg/kg b. wt.) induced changed in the concentration of the estimated essential elements in the various tissues examined of normal rats. The recorded changes in the tested trace elements pointed to (Zn), (Fe) and (Ca) content in liver, kidney, lung and testes tissues. Radiation exposure (4Gy) of rats produced marked alterations in the distribution of tested trace elements in all tissues investigated of irradiated rats, concerned with (Zn), (Cu), (Fe), (Ca), (Mg) and (Mn) in liver, kidney, lung and testes tissues. Combined exposure to γ-radiation (4Gy) and AgNPs (42.599 mg/kg b. wt.) treatment showed marked variation in trace elements content of (Zn), (Cu), (Fe), (Ca), (Mg) and (Mn) of the selected tissues examined. Such variations were more or less pronounced than the individual effects of either AgNPs treatments or γ-radiation exposure. The detected variation in the concentrations of the estimated trace Physico-Chemical and Organolyptical Characteristics Of Cake Fortified By Irradiated Broccoli (Brassica Oleracea L.Var It lica) Pow er 15


Over diagnosis of hospital-onset Clostridioides difficile infection (HO-CDI) is directly tied to inappropriate C. difficile testing which does not distinguish between infected or colonized individuals. This can lead to inappropriate therapy. Multiple studies have utilized Computerized Clinical Decision Support (CCDS) tools to reduce inappropriate C. difficile testing. Our study looks at the impact of a Self-Assessment CCDS tools on C. difficile testing for HO-CDI and oral vancomycin utilization as a balancing metric.

 Our institution utilizes a two-step test to diagnose HO-CDI that consists of toxin A/B enzyme immunoassay followed by a confirmatory PCR. We applied a self-assessment driven CCDS approach to reduce testing for HO-CDI. Our intervention was deployed in the 3rd quarter of 2018. It asked 3 questions about stool frequency, laxative use and previous C. difficile testing in the order itself. Inappropriate indications for testing included any of the following: < 3 bowel movements within 24 hours, receipt of a laxative within the past 48 hours, or a previous C. difficile test within the previous 7 days. Ordering providers would self-answer these questions. A 'yes' response to any of the three questions prevented further test ordering; though respondents had the freedom to change the answer and still proceed with the test order. We evaluated 3 metrics that were all calculated per 1000 inpatient census days: oral vancomycin usage, HO-CDI rates and C. difficile testing rates.

 Compared to baseline, our intervention resulted in a significant reduction of C. difficile testing and HO-CDI rates (Figure 1, Table 1). Oral vancomycin usage also decreased significantly (Figure 2, Table 1).
 Figure 1. C. difficile testing and Hospital Onset C. difficile Infection Rates by Month, Before and After Intervention

 Figure 2. Oral Vancomycin Utilization by Month, Before and After Intervention

 Table 1. Changes in Median Rates of C. difficile testing, Hospital Onset C. difficile Infections and Vancomycin Utilization, Before and After Intervention.

 Our self-assessment driven CCDS-based diagnostic stewardship resulted in a significant reduction in inappropriate C. difficile testing for HO-CDI and HO-CDI rates. Oral vancomycin utilization as a balancing metric also decreased significantly. This was despite the use of a self-assessment driven approach with the freedom to change the answers in order to proceed with the test order.

 All Authors: No reported disclosures


In this paper, we present robust adaptive controller design for a special class of linear system, which is composed of two SISO linear subsystems, S1 and S2, under noisy output measurements and sequentially interconnected with additional feedback. We formulate the robust adaptive control problem as a nonlinear Hinfin-optimal control problem under imperfect state measurements, and then solve it using game-theoretic approach. The cost-to-come function analysis is carried out to derive the estimators and identifiers of S1 and S2, and integrator backstepping methodology is applied recursively to obtain the control law, which guarantees the boundedness of closed-loop signals, and achieves asymptotic tracking under some assumptions. Moreover, the closed-loop system admits a guaranteed disturbance attenuation level with respect to the exogenous disturbance inputs, where the ultimate attenuation lower bound for the achievable performance level is equal to the noise intensity in the measurement channel of S1.


defenses, of commonplace disturbances of the self 's harmony, bespeaks such division. Since the self can be divided, indeed, fragmented, it is imperative that we make something of ourselves, some one thing. Consistency in practice is imperative because we are nothing apart from the regularities of our thoughts and actions. Commitment to practical consistency is commitment to the conception of ourselves as beings who take responsibility for themselves, as self-governors. The fact of this commitment is what underlies fully human experience and makes necessary the legislation of principles by which to govern. What is legislated are the principles of rationality. There are none prior to the legislation. Dayton cannot be right, then, when he says that the transparent version of the general principle of consistency for propositional attitudes is what makes the deliberation of our attitudes possible. For what underlies Dayton's principle and what rationality, finally, consists in is self-consistency "in the practical matter of the taking and refusing of commitments."


The utility model relates to a building structure and provides a long-span hydropower station underground power house, which comprises vertical columns and a ring beam consisting of beams. The ring beam is arranged at the tops of the vertical columns; a group of arch beams is arranged between the beams on two opposite sides of the ring beam; an arch slab covering the top of the whole power house is arranged above each arch beam; the arc of each arch slab adapts to that of each arch beam; each arch slab is supported by the corresponding arch beam and the beams on two sides; the arch slabs and the arch beams are in combined slab structures made of profiling steel formworks; and air inlets and return air inlets for communicating an upper space with a lower space of each arch slab are arranged on each arch slab. As the profiling steel formworks are adopted, construction speed is high. Moreover, the profiling steel formworks are used as not only formworks but also tensile reinforcement for the bottom surface of a cast-in-situ structure, and function in decoration. By the aid of the all reinforced concrete structure, the long-span hydropower station underground power house is simple and convenient in maintenance, integrally close, fine in heat insulation and moisture-proof effects, capable of meeting use requirements and avoiding the problem of vibration noise, and applicable to serving as a hydropower station underground power house.


Pre-post-filtering operators have been shown to improve the coding efficiency as well as to mitigate blocking artifacts in traditional DCT-based block coders. Pre-post-filters which preserve the system sampling rate have been extensively investigated. This paper explores the two noncritically-sampled signal decomposition cases - under-sampling and over-sampling - via the pre-post-processing perspective. We discuss various design issues, efficient structures, and present two application examples: under-sampled pre-post-filters for very low bit-rate image coding and over-sampled pre-post-filters for error resilient image transmission. Preliminary experimental results illustrate that noncritically-sampled pre-post-filtering does provide much improved coding performances than its critically-sampled counterpart for the aforementioned specific applications.


Solid compounds containing the complexes Al(taci) 2 3+ , Ga(taci) 2 3+ , and Tl(taci) 2 3+ (taci=1,3,5-triamino-1,3,5-trideoxy-cis-inositol=C 6 H 15 N 3 O 3 ) have been prepared by combining methanolic solutions of taci and of appropriate metal salts.


In present context of globalised markets, customers have become very choosy in terms of product selection. Along with low cost, on time delivery, convenience of giving order and purchasing has become very important for consumers. Therefore on line retailing is being very popular now a day. To work in such kind of environment, organisations need to be very careful in developing their processes and distribution channels. There are many factors, which influence success of online retailing. Based on literature review and discussion with industry professionals ten factors have been identified. These are on time delivery, inventory management, order tracking, less shipping cost, network optimisation, effective portal system, attractive offers on products, customer friendly policies, after sales service and advertisement through social media. These factors are ranked based on technique for order preferences by similarity to an ideal solution (TOPSIS) approach. Based on analysis, it is recommended that on line retailers should focus on timely delivery, attractive offers on products and effective portal system to influence new customers.