The current trend in the development of motor-and-tractor diesel engines imposes tough requirements on fuel equipment and the fuel supply process. The implementation of it is difficult to combine with the requirements of reducing heat generation at the initial stage of combustion and the rate of pressure increment to reduce exhaust emissions and engine noise. A decrease in the duration of the injection process and an increase in the volumetric feed rate lead to a growth in the cycle dynamism factor and an increase in the operation noise. This scientific article discusses the use of multiple injection of fuel in a diesel engine to reduce the emission of nitrogen oxides, smoke and particulate matter by improving the heat transfer processes, the mixture formation and, as a result, heat generation. Low exhaust gases toxicity and smokiness values are achieved.


This paper describes the apparatus and the procedures implemented to test the front-end (FE) electronics of the LHCb muon detector multi wire proportional chambers (MWPC). Aim of the test procedure is to diagnose every FE channel of a given chamber by performing an analysis of the noise rate versus threshold and of the performances at the operational thresholds. Measurements of the key noise parameters, obtained while performing quality tests on the MWPC chambers before the installation on the experiment, are presented. The test suite proved to be an automatic, fast and user-friendly system for mass production tests of chambers. It provided the electronic identification of every chamber and FE board, and the storage and bookkeeping of test results that will be made available to the experiment control system during data taking.


High-strain-rate biaxial punch tests were performed on DOP-26 (Ir-0.3 wt.% tungsten) iridium-alloy disc given annealing and aging heat treatments. Test temperatures ranged between 600 and 1440/degree/C, and punch velocity was held constant at 45 m/s. Three types of samples were evaluated: Z-batch old-process discs, B-batch old-process discs, and B-batch new-process discs. The results indicate that batch-to-batch variations in ductility are significant and that new-process iridium is slightly more ductile than old-process material. 12 refs., 43 figs., 26 tabs.


It is a focus issue for exploring the road to China's overall social development in the 21st century to clarify the relationship between MAO Zedong thought and the theory system of socialism with Chinese characteristics.The relationship between the two is not "one dosen't contain the other"or "one contains the other",but it is an intrinsic unity.This needs to be holisticly understood,and "history of ideas",theory and practice,philosophy and "theory function" may be taken as integration paths


The quantification objective is to predict the class distribution of a data sample. Therefore, this task intrinsically involves a drift in the class distribution that causes a mismatch between the training and test sets. However, existing quantification approaches assume that the feature distribution is stationary. We analyse for the first time how score-based quantifiers are affected by concept drifts and propose a novel drift-resilient quantifier for binary classes. Our proposal does not model the different types of concept drifts. Instead, we model the changes that such changes cause in the classification scores. This observation simplifies our analysis since distribution changes can only increase, decrease or maintain the overlap of the positive and negative classes in a rank induced by the scores. Our paper has two main contributions. The first one is MoSS, a model for synthetic scores. We use this model to show that state-of-the-art quantifiers underperform in the occurrence of any concept drift that changes the score distribution. Our second contribution is a quantifier, DySyn, that uses MoSS to estimate the class distribution. We show that DySyn statistically outperforms state-of-the-art quantifiers in a comprehensive comparison with real-world and benchmark datasets in the presence of concept drifts.


Using the framework of communication accommodation theory, the authors examined convergence and maintenance on evaluations of Chinese and Australian students. In Study 1, Australian students judged interactions between an Anglo-Australian and another interactant who either maintained his or converged in speech style. Results indicated that participants were aware of convergence but that speaker ethnicity (Anglo-Australian, Chinese Australian, or Chinese national) was a stronger influence on evaluations and future intentions to interact with the speaker In Study 2, Australian students judged Chinese speakers who maintained communication style or converged on interpersonal speech markers, intergroup markers, or both types of markers. Results indicated that the more participants defined themselves in intergroup terms, the more positively they judged intergroup convergence relative to interpersonal convergence and maintenance. This points to the importance of distinguishing between convergence on interpersonal and intergroup speech markers, and underlines the role of individual differences in the evaluation of convergence.


Aquaculture can lead to eutriophication and High organic matter in aquatic system.At the same time,multipile physical and chemical water paramates will change such as dissolve oxgen and pH decrease,sufide(sulfate) and organic matter increase in sediment,and destroying biological community composition,which affact by using the fish pharmaceutical as well excreta input.The efflunce on methylation of mercury in aqautic system from aquaculture has not well understanding,and few reseach is done till now.Therefore,it is very necessary for reasonablly utilizing and developing reservoir resources in future management.


Introduction: It is imperative, if not fundamental, for medical students to receive continuing education in Basic life support (BLS). This present study aimed to investigate the effectiveness of continuing education using social media in this regard. Methods: In this quasi-experimental study, a questionnaire containing 20 items about BLS awareness was completed by the interns who were trained monthly in the emergency medicine training course. Then half of the interns received distant education through Telegram software up to three months, and the other did not receive any further education. Again, both groups completed the questionnaire at the end of the third month. Results: 100 medical interns with the mean age of 25.05 ± 1.26 years were allocated to two groups of 50 subjects (65.0% female). Two groups were similar regarding the mean age (p = 0.304), gender (p = 0.529), mean awareness score at the beginning of the study (p = 0.916), and average pre-internship exam score (p = 0.080). The mean awareness score of medical interns increased significantly in intervention (11.44 ± 2.37 to 14.88 ± 1.97, p < 0.0001) and control (11.38 ± 3.22 to 12.54 ± 3.04, p < 0.0001) groups at second examination. But mean difference of awareness score, before and after the education, was significantly higher in intervention group (3.44 ± 1.48 versus 1.16 ± 1.51; p < 0.0001). Conclusion: The increase in the BLS awareness score was significantly higher in medical interns who were continuously educated using Telegram social media software.


An array of atmospheric aerosol optical characteristics is obtained from synchronous measurements on a long nearground path and in a local volume of air. The algorithm of statistical comparison of the data obtained is modernized. The spectral dependence of the single scattering albedo in the wavelength range 0.45 to 3.9 μm is calculated. Non-monotonic increase of albedo with wavelength is observed. Seasonal variations of albedo are estimated. Minimum values of albedo are observed in April and October, and maximum values are in July.


Shadow vehicles are used to protect freeway maintenance activities from other vehicles. Annually, many shadow vehicle drivers are seriously injured or killed due to errant drivers. This paper presents an overview of an autonomous shadow vehicle research and development project. The driver-less shadow vehicle can track a lead vehicle, such as a road sweeper, or be driven using a remote control box for stop and go freeway maintenance operations. An overview of the lead vehicle user interface and tracking systems employed and control strategies used are also presented. The autonomous shadow vehicle is currently under development and testing.


Manual grading of essays by humans is time-consuming and likely to be susceptible to inconsistencies and inaccuracies. In recent years, an abundance of research has been done to automate essay evaluation processes, yet little has been done to take into consideration the syntax, semantic coherence and sentiments of the essay's text together. Our proposed system incorporates not just the rule-based grammar and surface level coherence check but also includes the semantic similarity of the sentences. We propose to use Graph-based relationships within the essay's content and polarity of opinion expressions. Semantic similarity is determined between each statement of the essay to form these Graph-based spatial relationships and novel features are obtained from it. Our algorithm uses 23 salient features with high predictive power, which is less than the current systems while considering every aspect to cover the dimensions that a human grader focuses on. Fewer features help us get rid of the redundancies of the data so that the predictions are based on more representative features and are robust to noisy data. The prediction of the scores is done with neural networks using the data released by the ASAP competition held by Kaggle. The resulting agreement between human grader's score and the system's prediction is measured using Quadratic Weighted Kappa (QWK). Our system produces a QWK of 0.793.


The legal obligation for the members involved in multi lateral trade which are specified by WTO mainly deal with the obligations of governments of its members. They are regarded as the functional activities of the governments rather than commercial and trading activities. A new topic for the jurists to study is how to develop a legal system of administration which may be in line with WTO so as to standardize and guarantee the orderly operation adaptable to WTO. The basic concepts of constructing a legal system of administration which is in line with WTO include the following: 1) promoting the legislation, amendment and abolition of the legal system of administration; 2) improving the art of exercising administrative rights by law; 3) intensifying the supervising mechanism of legal system of administration.


This study aims to identify effective internationally emerging implementation models in teacher professional development. Several trends in teacher Professional Development are influencing the nature and quality of teacher professional development. The meta-analysis method was used in this study by identifying, collecting, and analysis potential studies to reach the findings. The results show that professional development has the potential to transform the education scene when supported by all industry players. Policy plays a vital role in the success of programs like PD programs. Policies surrounding the government of this model should be carefully structured to guide the PD programs appropriately as well as formulators should be industry players who understand the drivers that affect the education sector and in particular the educators. Good policy choices will mean that the PD stands a chance to be effective. The PD program should be provided with all the necessary resources for it to be effective and to enable smooth running. Educators should be facilitated with the necessary materials they require for the program. Lack of resources means that the PD program will not achieve its intended goals. Resources might be learning resources for the educator, allowances among many others. Extensive collaborations should be done by the sectors that could play a strong role in affecting the education, stakeholders, investors and other parties related in order to reach an agreement on the best model of PD. Additionally, there is a need to determine how best to run the PD programs to be beneficial to the education system.  Article visualizations:


In this paper, a dynamics behavior of a delayed hepatitis B infection model with exposed state and humoral immunity is studied. The basic reproductive number R0and humoral immune reproductive number R1are introduced. By using suitable Lyapunov functional and LaSalle invariant principle, it is proved that when R0 1, the sufficient conditions to the local stability of the infected equilibrium with immunity Q2can be obtained. The time delay can change the stability of Q2and lead to the existence of Hopf bifurcations. The stabilities of periodic solutions are also investigated. Finally, numerical simulations are carried out.


Work shift systems are often implemented by companies to increase production targets.shift system can have an impact on health problems both acute and chronic experienced by workers.Age can affect the physical condition and endurance of workers where as they get older the immune system will decrease and be vulnerable to health problems. This Study was aimed to know correlation between age andhealth problems acute and chronic in shift workers at PT. Dan Liris Sukoharjo. This research uses observational analytic method with cross sectional approach. Population in this research is the shift workers weaving II totaling 229 worker. Cluster Random Sampling method was used to take sample. Data taken from respondents by interview using a questionnaire.Statistical tests using the Spearman rank correlation test with a significant level of p value = 0.01 and r = 0.24 in acute health disorders and p value 0.01 with r = 0.24, which shows the corrrelation between age andhealth problems acute in workers. It is recommended for shift workers PT. Dan Liris Sukoharjo to maintain physical fitness with exercise and must be able to divide normal sleep time.


Principal instructional leadership has been found to support improved instruction. However, the methods through which principal leadership influences classroom instruction are less clear. This study investigates how principals' leadership may predict the expectations that mathematics teachers perceive for classroom practice. Results from a hierarchical generalized linear (HGLM) model, using data from four urban school districts, show that the principal's work to frame instructional vision, and the principal's own vision, both predict perceived instructional expectations. However, other conventional leadership activities are not predictive. Finally, principals appear to provide a baseline of expectations for standards-based mathematics instruction rather than comprehensive expectations.


No record of the railway should be destroyed until after the expiration of the period prescribed for its preservation and full details should be maintained permanently of all records destroyed from time to time, Subject to any orders issued by the Railway Board, in a particular case, the periods for which the records of the railway shall be preserved, should be prescribed by the General Manager, except that the periods for the preservation of records of initial accounts in the executive offices and for other records {including correspondence) in such offices as may be connected with the accounts rendered to the Accounts Department, should be prescribed after consultation with the Financial Adviser and Chief Accounts Officer.


In this paper we present an approach for fruit recognition using artificial vision, towards to employ it as an application for supermarkets. The fruit's visual features extracted are shape, texture and -we focus on- the extraction of the color chromaticity. From the few related works on fruit recognition, the color extraction is performed in the RGB (Red, Green, Blue) space. We claim as necessary to employ the chromaticity of colors to characterize the color of the fruits. Thus, we propose to use the HSV (Hue, Saturation, Value) space because it is possible to extract and process the chromaticity data, but without the undesirable intensity effects of the RGB space. On the other hand, before the color is characterized, we complete a selection of the chromaticities that contribute with important data about the fruits. Our approach's strength is validated by performing test on 20 common fruit classes: this proposal outperforms the color characterization of related work.


Model reduction is a major issue for control, optimization and simulation of large-scale systems. We present a formal procedure for model reduction of perturbed linear second-order differential equations. Second-order equations appear in a variety of physical contexts, e.g., in molecular dynamics or structural mechanics to mention just a few. Common spatial decomposition methods such as Proper Orthogonal Decomposition, Principal Component Analysis or the Karhunen-Loève expansion aim at identifying a subspace of "high-energy" modes onto which the dynamics is projected (Galerkin projection). These modes, however, may not be relevant for the dynamics. Moreover these methods tacitly assume that all degrees of freedom can actually be observed or measured. An alternative procedure is known by the name of Balanced Truncation which is a method of model reduction for stable input-output systems. Unlike the aforementioned approaches Balanced Truncation accounts for incomplete observability. It consists in finding a coordinate transformation such that modes which are least sensitive to the external perturbation (controllability) also give the least output (observability) and therefore can be neglected. Accordingly, a dimension-reduced model is obtained by restricting the dynamics to the subspace of the best controllable and observable modes. A great advantage of the method is that it gives computable a priori error bounds; a drawback is that it typically fails to preserve the problem's physical structure and suffers from lack of stability [1, 2]. Here we adopt the framework of port-Hamiltonian systems which covers the class of relevant problems and that allows for a generalization of Balanced Truncation to second-order problems, while preserving stability and the underlying Hamiltonian structure. The restriction to the controllable/observable subspace is done by imposing a holonomic constraint using techniques from singular perturbation theory for deterministic or stochastic differential equations. Given a quadratic Hamiltonian H : R ×R → R, we consider the system


The current problems on damping in seismic response analysis of bridges is presented. The Rayleigh damping theory is simply introduced in this paper. Taking the Longtan River Bridge for instance, the finite element model of Longtan River Bridge (left line) is established. Then, the dynamic properties of the bridge is analyzed. Based on this, the Rayleigh damping constants and in an ANSYS dynamic analysis are obtained.


A characterization of simplicial objects in categories with finite products obtained by the reduced bar construction is given. The condition that characterizes such simplicial objects is a strictification of Segal's condition guaranteeing that the loop space of the geometric realization of a simplicial space X and the space X1 are of the same homotopy type. A generalization of Segal's result appropriate for bisimplicial spaces is given. This generalization gives conditions guaranteing that the double loop space of the geometric realization of a bisimplicial space X and the space X11 are of the same homotopy type.


The behavior tendency of the related interest group during the property rights exchange process is analyzed.Basing on the prospect theory,the paper proposes a trilateral game model including the supervisor,the agent and the purchaser,also finds out the Nash equilibrium solution in the mixed strategy and the best supervisory probability of the supervisor.The paper gives an analysis of the behaviors and strategies of the supervisor,the agent and the purchaser,and suggests the supervision should be directed against agents and purchasers according to their different behaviors.


Supergrid is a grid that enables to transfer electricity produced by renewable sources from the production places, located in regions, like ocean coasts and Sahara desert, to the consumptions centers. Several projects were developed supported by EU in last years and others will be proposed on such topic in the next future. In this paper the authors propose a method able to evaluate the projects in terms of their compatibility with the EU policy.


The authors carried out the life cycle assessment (LCA) for metallic nickel produced by pyrometallurgy processes based on the investigations. The production processes of nickel, which use nickel-copper coexistence ore as the raw material, are a complex production system and deal with nickel, copper and other metals production; therefore, the LCA study is rather complicated. The environmental impacts are distributed to each product, according to the mass flow combined with the energy consumption, and a LCA case study for the complex metallurgical processes is offered. The assessment indicates that the processes, which cause the largest energy consumption and waste gases emission, are mining, ore preparation and electrolysis processes. The processes, which cause the largest amount of waste water and solid waste, are mining process. The improving ways of them are also discussed.


Crane selection is an important issue in assembly works planning. Tower and telescopic, stationary and mobile cranes used in construction have essentially different properties. Assembly planning begins in analyzing the possibilities of assembly with a given crane. This is called technical aspect of crane selection. Cranes that meet the technical criteria are then analyzed in terms of other criteria related to the effectiveness of their use on the construction site. The article presents the assessment of the selection criteria and the method of crane selection itself. Surveys conducted among construction managers and planners in Polish companies dealing with assembly works allowed to determine the significance of the selection criteria. For this purpose, an example using SAW (Simple Additive Weighting) and FSAW (Fuzzy Simple Additive Weighting) methods was presented. They also allowed to propose a technique for determining preferences in the use of selected construction cranes. The aim of the research was to increase the usability of computer applications supporting assembly planning by acquiring expert knowledge for the initial selection of organizational solutions.


Methane gas is a promising potential source for the future energy needs of humanity. The author will describe the analytical method of predicting the production profile of gas and water of a Coal Bed Methane (CBM) field, using the material balance of a modified G.R. King iteration procedure. The author has concluded that some of the steps within the iteration procedure of G.R. King are not suitable, and has thus applied a mathematical analysis to correct G.R. King's iteration procedure, to allow the prediction of a production profile in a CBM field. With the newly-modified iteration procedure, the author applied the material balance technique with data given by G.R. King (SPE 20730) and working from other references was able to generate a production profile for a CBM field. The author also applied the Corey Correlation for gas and water to ascertain whether it is suitable or not to generate the production profile of a CBM field. The author concluded that the modified G.R. King iteration procedure is analytically suitable for the production profile of a CBM field. However, the Corey Correlation has never been found suitable to precisely describe the characterization of a CBM production profile. Moreover, the author tried to analyze many different values within Corey parameters, and in this paper posits that the most suitable parameter to be changed is the Corey exponent. The larger the value of the water saturation exponent, the longer the time consumed for water recovery. The larger the value of the gas saturation exponent, the longer the time consumed for gas recovery; this creates a different production profile for as CBM field.


This study was designed to assess the effects of different types of organic matter on the quality and biochemical properties of red seedless watermelon. The research was a single factor experiment, which involved six (6) treatments and four (4) replications. Watermelon grown and harvested from five (5) different organic matter sources, namely; vermicompost (VC), poultry manure (PM), cow dung (CD),  goat dung (GD),  and moringa leaf extract (MLE), at the rates of 10 ton, 20 ton, 30 ton, 30 ton, and 3000 L ha-1, respectively, were used in this study. The results revealed that the treatment of vermicompost improved the chlorophyll content, chlorophyll fluorescence, stomatal conductance, internal carbon dioxide, net photosynthetic rate, fruit weight and mineral nutrient content of watermelon. The application of cow dung reduced the rind thickness and increased the TSS and antioxidant activity of the watermelon.  The goat dung treatment significantly affected fruit size, juice content and the pH content of the watermelon's fruit juice. The poultry manure (PM) and moringa extract (MLE) treatments resulted in the highest anthocyanin content of all the watermelon. Although all the organic matter, in their unique ways, improved the quality of red seedless watermelon, the study shows that the vermicompost application had better growth, yield and improvement in the quality of watermelon.


The feedback Group Method of Data Handling (GMDH)-type neural network algorithm is proposed and is applied to 3-dimensional medical image recognition of the lungs, the pulmonary vessels and the bronchial trees. In this feedback GMDH-type neural network algorithm, the optimum neural network architecture is automatically selected from three types of neural network architectures such as the sigmoid function type neural network, the radial basis function (RBF) type neural network and the polynomial type neural network. Furthermore, the structural parameters such as the number of layers, the number of neurons in the hidden layers and the relevant input variables are automatically selected so as to minimize the prediction error criterion defined as Prediction Sum of Squares (PSS). The recognition results show that the feedback GMDH-type neural network algorithm is useful for the 3-dimensional medical image recognition of the lungs, the pulmonary vessels and the bronchial trees and is ideal for such practical complex problems since the optimum neural network architecture is automatically organized.


To increase the robustness of visual processing in the context of mobile robotics, we introduce an image filtering process based on the codebooks computed by the SOM. The Self Organizing Map and the Simple Competitive Learning are used to compute adaptively the vector quantizers of color image sequences. The codebook computed for each image in the sequence is then used as a smoothing filter, the VQ Bayesian Filter (VQ-BF), for the preprocessing of the images in the sequence. This filter is applied to the computation of optical flow at the single pixel level.


Groundwater makes up almost 99 % of available freshwater sources on Earth. However, Malaysia's freshwater supply comprises less than 10 % of groundwater. As the water shortage crisis becomes more severe, attention has shifted towards utilizing groundwater. However, due to progressing urbanization and the increase in population, the treatment of groundwater is necessary to ensure safe consumption. This research focuses on the hydrochemistry of groundwater samples collected from 3 different sites located in Johor, Malaysia. The main objective of this study is to establish the quality of groundwater in terms of its physicochemical properties to determine its viability to be used as drinking water. The important physical properties of groundwater such as pH, conductivity, total dissolved solids (TDS), and ion concentration analysis were conducted in the lab. The chemical composition of the groundwater was determined where major cations (Ca 2+ , K + , Mg 2+ , Na + ) and anions (HCO 3- , F - , NO 3- , SO 42- , Cl - ) concentrations are present in the groundwater together with several trace elements (Si, Al, As). The results of ion concentration analysis obtained for the groundwater samples were compared with the guidelines set by the Ministry of Health Malaysia (MOH) for drinking water quality to check whether it adheres to the standard values or not since excess of any mineral ions can cause severe health implications. The analysis data indicated that Ca 2+ is the major cation present in all the samples at the highest concentration while HCO 3- is the dominant anion that exists at an abundant concentration in all the groundwater samples. According to the analysis results obtained, it can be deduced that the groundwater samples from all three locations can be classified into the bicarbonate-calcium-rich type of water category. The groundwater samples also adhere to the quality limit set by MOH for the major ions' concentration, establishing the potential of groundwater for consumption purposes and household needs as well.


Multilayered nanovectors made up from a controlled binary lipid mixture (POPC and DMPS) and trimethyl chitosan (TMC) have been prepared and characterized by light- and small angle neutron scattering. The morphology and the multilayer structure of the particle outer shell has been described in detail. By varying the amount of TMC in the starting solution it is possible to tune the overall surface particle charge as well as its multilamellarity. In this way the drug loading/release properties of the particles can be controlled. Therefore the use of controlled POPC/DMPS mixtures can be a valid alternative to commercial lecithin to obtain nanovectors with specific release properties.


Excerpt Despite the common occurrence of oral and esophageal candidiasis in patients with the acquired immunodeficiency syndrome (AIDS), the relationship between infection in one site to that in th...


Sodium caseinate was hydrolyzed with commercial Neutrase 15 MG.The dosage of Neutrase was(1∶1 000,) and the substrate concentration was 85%.The reaction time was 2,10 and 48 h,respectively.The molecular weight distribution of hydrolysis was identified by high performance size exclusion chromatography(HPSEC).The process of enzymatic reaction was quantitatively characterized based on the peptide mapping.


Objective—Natural killer (NK) cells have been identified in human vascular pathologies. In this study, we identified NK cells in aortic root atherosclerotic lesions of low density lipoprotein (LDL) receptor–deficient (LDLr−/−) mice. To characterize the role of NK cell–mediated cytolysis in atherosclerosis, we generated C57Bl/6 double-mutant mice by crossing LDLr−/− mice with NK cell–defective Lystbeige mice (creating beige,LDLr−/− mice) and with perforin-deficient mice (creating Pfp−/−,LDLr−/− mice). Methods and Results—Male mice (8 to 10 weeks old) were fed a high-fat diet to induce atherosclerosis. Compared with LDLr−/− mice, beige,LDLr−/− mice had impaired NK cell cytolytic activity and significantly increased atherosclerosis (P <0.05). Pfp−/−,LDLr−/− mice had impaired NK cell cytolytic activity, yet they had lesions that were similar to those of control mice. This suggested that NK cell cytolysis did not play a significant role in atherosclerosis and that the exacerbated atherosclerosis of the beige,LDLr−/− mouse was independent of impaired NK cell cytolytic activity. Therefore, we investigated the role of T and B lymphocytes in atherosclerosis of beige mice by crossing them with recombinase activator gene 1–deficient LDLr−/− mice (Rag1−/−,LDLr−/− mice), thus creating beige,Rag1−/−, LDLr−/− mice. As in the double-mutant study, beige,Rag1−/−,LDLr−/− mice had significantly increased lesions compared with Rag1−/−,LDLr−/− control mice. Conclusions—Therefore, the Lystbeige mutation in LDLr−/− mice has proatherogenic properties that are independent of NK cell–mediated cytolysis and lymphocyte-mediated acquired immunity.


CONTEXT
There is a need for models of health care that provide accessible, culturally appropriate, quality services to the population of Hispanic migrant farmworkers at risk for or diagnosed with diabetes.

PURPOSES
The purposes of this study were to describe the Migrant Health Service, Inc (MHSI), Diabetes Program, the conceptual model on which it is based, and 4 types of outcomes achieved over a 3-year period.

METHODS
Types and amounts of medical services and education were studied. Qualitative data obtained from program records and documents were analyzed to determine the nature of the program. Quantitative data were used to measure outcomes of the program.

FINDINGS
The multiplecomponent MHSI Diabetes Program is addressing economic, cultural, and language barriers experienced by the target population. The program provides a continuum of health services and education that meet American Diabetes Association (ADA) Clinical Practice Recommendations on diabetes. The program exposes regional health care professionals and university students from numerous academic disciplines to Hispanic farmworker culture.

CONCLUSIONS
Evidence-based program management, patient care, and program evaluation are traits of this program, which offers accessible, culturally appropriate, quality health services and education to Hispanic farmworkers. The multicomponent program model has high potential for positively impacting the health of the target population.


The banana's industrialization is an option to make good use of the surplus production and of the fruits that are out of quality standards for raw consumption. An alternative use of banana is its nectar form, which is a good nutritional beverage that is ready for consumption and of easy processing. This work's primary objective was to prepare the nectars from acidifi ed mashed bananas of the varieties Prata, Brazilian Dwarf and Marmelo. Moreover, characterize chemically the nectar, its sensorial acceptance and evaluate its intention of purchase. The average of pH values found for the three nectars varied from 4.49 to 4.59; the total tenor of soluble solids varied from 8.8o Brix to 10.97o Brix; the total titratable acidity varied from 0.29% to 0.37%; the tests of reducing sugars varied from 10.92% to 12.76% and of non-reducing sugars varied from 8.51% to 12.41%. The color sensorial evaluation of the banana's nectar showed that the varieties Marmelo and Prata had the higher averages and that their difference were negligible (p≤0,05). The fl avor of the variety Brazilian Dwarf presented the best acceptance. Global appearance did not show signifi cant difference between Marmelo and Brazilian Dwarf varieties. The purchase intention pointed the Brazilian Dwarf variety being the most accepted, with acceptance rate between "probably would buy" and "perhaps would buy / perhaps would not buy"


The invention discloses a preparation device for in-situ vertical isolating engineering barrier material. The preparation device comprises a first motor, a second motor, a first bearing, a second bearing, a stirring tank, a first stirring blade connector, a second stirring blade connector, a first stirring blade and a second stirring blade. Slurry jetting pipes with jetting openings are arranged on the side surface of the stirring tank. A power output shaft of the first motor is connected to one end of the first bearing, the other end of the first bearing is fixedly connected to the first stirring blade connector, and the first stirring blade is fixedly connected to the first stirring blade connector. A power output shaft of the second motor is connected to one end of the second bearing, the other end of the second bearing is fixedly connected to the second stirring blade connector, and the second stirring blade is fixedly connected to the second stirring blade connector. The invention further discloses a preparation method for the in-situ vertical isolating engineering barrier material. The preparation device and method effectively achieves in-situ, efficient and uniform preparation of the soil-bentonite vertical isolating engineering barrier material.


The well-known vertex enumeration problem calls for generating all vertices of a polyhedron, given by its description as a system of linear inequalities. Recently, a number of combinatorial techniques have been developed and applied successfully to a large number of monotone generation problems in different areas. We consider four such techniques and give examples where they are applicable to vertex enumeration. We also discuss their limitations and sketch an NP-hardness proof for generating the vertices of


The surface of much equipment that employed in petrochemical industry is always damaged by corrosion. As a novel technology, laser-high frequency induction hybrid cladding is an effective surface modification technology. Processing parameters, such as laser power, laser scanning speed and induction heating temperature, play an important part in the structural integrity of the coatings. The effects of these processing parameters to cladding integrity were investigated in this paper. Nickel base alloy (Ni60A) claddings were fabricated on the surface of low alloy steel by the way of laser-high frequency induction hybrid cladding and coaxial powder feeding. Macroscopic appearance and porosity of the claddings were systematically investigated by optical microscopy. The corrosion resistance of specimens manufactured by the optimum processing parameters is evaluated in 3.5% NaCl solution by electrochemical test. As the change of processing parameters, the width, height and porosity of laser claddings had an obvious change. Optimum processing parameters was determined because of the overall performance of the claddings. A good metallurgical bonding between Ni60A claddings and substrate was shown by microstructure. The results of the polarization curves turned out that the corrosion resistance of the Ni60A cladding is apparently better than the matrix.


NV centers in silicon carbide have been identified in the three main polytypes 3C, 4H, 6H by magnetic resonance and photoluminescence experiments and related ab initio calculations. Their properties show them to be promising centers for applications in quantum technology, similar to the case of NV in diamond. However, their spectral range is in the near-infrared, which should allow their integration in telecommunication systems.


GaAs has been grown on Ge substrate oriented 9° off towards ( 110 ) by atmospheric pressure MOVPE. Various growth temperatures and rates were tried to get device quality epitaxial layers suitable for solar cell applications. It was observed that the growth temperatures and the growth rates affect the surface morphology, optical properties and crystalline quality of the epitaxial layers. This was studied using optical microscope, photoluminescence and double crystal x-ray diffractometry.


The novel nonlinear thermoelastic behavior of shape-memory alloys (SMAs) makes them increasingly desirable as components in many advanced technological applications. In order to incorporate these materials into engineering designs, it is important to develop an understanding of their constitutive response. The purpose of this thesis is to develop a constitutive model of shape-memory polycrystals that is faithful to the underlying micromechanics while remaining simple enough for utility in engineering analysis and design. We present a model in which the material microstructure is represented macroscopically as a recoverable transformation strain that is constrained by the texture of the polycrystal. The point of departure in this model is the recognition that the mechanics of the onset of martensitic transformation are fundamentally different from those of its saturation. Consequently, the constraint on the set of recoverable strains varies throughout the transformation process. The effects of constraint geometry on the constitutive response of SMAs are studied. Several well known properties of SMAs are demonstrated. Finally the model is simply implemented in a commercial finite-element package as a proof of the concept.


Radioactive material packages containing fiberboard insulation have been subjected to Hypothetical Accident Condition (HAC) thermal tests for many years. Historically, the packages` thermal performance has always been difficult to grasp. A package designer needs to understand the effects of temperature and pyrolysis on the rate of heat transfer and performance. This paper describes in detail the one-dimensional HAC thermal tests performed on fiberboard to understand the effects of pyrolysis, its char and its gas products. The tests were conducted by the Packaging and Transportation Group at the Savannah River Site (SRS). Test fixtures were assembled at SRS and thermal testing conducted in the Radiant Heat Facility at the Sandia National Laboratories. Descriptions of the test fixtures are provided, as well as the time dependent temperature profiles. In addition, lessons learned are discussed.


Improved healthcare provision has led to substantial increases in life expectancy, yet cardiometabolic diseases (CMD) [cardiovascular diseases (CVD) plus type 2 diabetes] remain major causes of death and morbidity. In particular, the prevalence of type 2 diabetes continues to increase rapidly in the UK and other parts of the European Union. It therefore remains critical that diet, an important chronic disease risk modifier, is optimized to reduce risk. Milk and dairy products are perhaps the most misunderstood foods habitually consumed by large sections of the population.


The Second Avenue Subway is a major transportation project in the New York region, which will significantly expand MTA's subway system. Second Avenue Subway is currently the largest underground infrastructure project in the World. The project will generate enormous benefits for the residents and businesses of New York City and the New York region. The paper chronicles the history of the Second Avenue Subway Project from its original inception in 1929 to the current Preliminary Engineering stage of design. The paper discusses the project as a whole and then focuses on some of the unique challenges facing client and designer when dealing with underground construction in New York City.


Jule Gregory Charney, Alfred P. Sloan Professor of Meteorology at the Massachusetts Institute of Technology, died June 16, 1981, at the Sidney Farber Cancer Institute. He was the leading world figure in meteorology ever since he and John von Neumann first introduced the electronic computer into weather prediction in 1950.


Iowa Governor Norman Erbe ad· vocated a "fresh approach" Thursday night to find the most econom· Ical means of using state funds for the institutions of higher learning. Speaking at a meeting of the sur Young Republicans on "High· er Edllcation and the Legislature," Erbe urged wider utilization of junior colleges in Iowa by raising their standards and possibly by placing them under control of the Board of Regents. En,. seid many students .re "groping Iround" when they en· ter colleg. or ere not int.rested In more thin two y.ers of educ.· tlon. Their schooling, h. said, could b. tak.n cere of et Ihom. with I.IS ",pense to the ltudent end I.ss load on the thrH stet. coll.,.s. Erbe also urged " investigation of the tri -semester plan as another way to "fully utilize physical fa , cilities. I don't know whether it would work in Iowa," he said, "blit it has been workatlle in oth· er schools." Bet t e r coordination between Iowa's three state eolleges by ex) changing professors, . eliminating duplication of curricula and setting up similar seme$ter terms were also suggested by Erber fi. pointed out t!'et tM ~I, • question before the 1"lllatUre now II where to ,.t the m_y for the 25 per c'nt incr.... In It... Ic:hool epproprletions end for property tax r.llef. L"ookrng Chipper. \


The light emitted by high-speed particles produced by a Van de Graaff accelerator and excited by passage through a thin foil of carbon has been studied in the wavelength range 2700–6600 A. Lines from deuterium, helium, nitrogen, and oxygen are presented including some that have not previously been reported. Qualitative observations are presented on the mean lives of the excited states and on the dependence of spectral line intensity upon particle energy.


Abstract Aim The aim of this study was to compare the normative dental needs and sociodental needs in a sample of 18–21-year-old students in Davangere city in South India. Method This cross-sectional survey was conducted on a sample of 250 students aged 18–21 years. Data was collected using a self-administered questionnaire and clinical examination. The normative needs were assessed by different indices. The impact of oral diseases on their quality of life was assessed using the standard Oral Impact on Daily Performance (OIDP) scale and propensity-related needs (PRNs) were assessed using three standard questions. Results About 85.6% of the subjects fulfilled the criteria for professionally judged normative treatment need. Among them, 42% of the subjects were suffering from emergency/progressive oral conditions and the remaining 43.6% subjects were suffering from non-progressive oral conditions. In turn, a total of 28.4% of the subjects with non-progressive oral conditions fulfilled the criteria of impact-related treatment need. Finally, only 1.2% had sociodental needs (high PRNs). Conclusions A substantial reduction in treatment needs were found with the sociodental approach among youths in India. The considerable proportion of the children with impact-related need (IRN) did not have a high behavioral propensity, hence potentially needing alternative interventions and programs.


The PRISM (partial risk map) methodology is a novel risk assessment method developed as the combination of the failure mode and effect analysis and risk matrix risk assessment methods. Based on the concept of partial risks, three different aggregation functions are presented for assessing incident risks. Since the different aggregation functions give different properties to the obtained PRISM numbers and threshold surfaces (convex, concave, linear), the description of these properties is carried out. Similarity analyses based on the sum of ranking differences (SRD) method and rank correlation are performed and robustness tests are applied related to the changes of the assessment scale lengths. The PRISM method provides a solution for the systematically criticized problem of the FMEA, i.e., it is not able to deal with hidden risks behind the aggregated RPN number, while the method results in an expressive tool for risk management. Applying new aggregation functions, proactive assessment can be executed, and predictions can be given related to the incidents based on the nature of their hidden risk. The method can be suggested for safety science environments where human safety, environmental protection, sustainable production, etc., are highly required.


Objective: To analyze the MRI characteristics of fetal sacrococcygeal teratoma and to determine the value of prenatal MRI.Materials and Methods: From December 2009 to January 2012,7 cases suspected of having fetal sacrococcygeal tumors by ultrasound,MRI was performed in all of the cases.Pregnant women aged 21~33 years,with the gestational age of 24 weeks to 37 weeks+5,the size,location,signal characteristics,and compressive effects of the masses were determined.Results: The sacrococcygeal teratoma appeared entirely cystic in six fetuses,mixed cystic and solid in 1,type Ⅰ in two patients,type Ⅱ in 2,and type Ⅲ in 1,type Ⅳ in 2,MRI findings of fetal sacrococcygeal teratomas were as follows: fetal sacrococcygeal region tumors with low T1 high T2 signal intensity,the sacrococcygeal teratomas with septa in two,intrapelvic and intraabdominal extent of the tumor in two.which was proved by follow-up or pathologic findings.Conclusion: Fetal sacrococcygeal teratomas had characteristic MR imaging appearances.


The purpose of this study is to provide basic information to improve understanding of contemporary kimchi culture in Korea. Many Koreans are now purchasing kimchi at markets, while the proportion of self-preparation is gradually decreasing. This commodification tendency of kimchi is considered to be associated with changes in consumer's behavior and attitude. In this study, a linear regression and a logistic regression model were used to identify relationships between kimchi consumption behavior and household characteristics. The results showed that the probability of kimjang activity was positively related with family size, possession of a kimchi refrigerator, self-preparation practice, and the intensity of sharing behavior. I also found that kimchi consumption volume per capita of 'purchasing' household was greater than that of 'selfpreparing ' or 'sharing-dependent' households, and that the number of family members was inversely related with kimchi consumption volume per capita. The inverse relationship between family size and kimchi consumption volume per capita is considered to be contrary to the widespread thoughts in Korea, which have been developed while experiencing kimchi preparation and consumption in traditional extended families. I think that the relationship comes from differences in menu varieties, which appear to vary with family size. This issue will be investigated in subsequent studies.


A fast and efficient method for measuring high-order Volterra kernels along the axis is given in this paper. Using the conclusions of the authors' previous paper (see IEEE ISCAS 1990, vol.1 p.184-7, May, 1990), and combining a DC component with the input signal, the high-order kernels H/sub 2/ (jf,0), H/sub 3/ (jf,0,0) and H/sub 3/ (jf/sub 1/, jf/sub 2/, 0) can be measured with many points.<<ETX>>


Direct wafer bonding was performed under medium vacuum conditions. The effects of the sequence of wafer contact and vacuum application, annealing temperature, and annealing time on the bonding quality and bonding speed were investigated. From the comparison of the bonding efficiency, contacting two wafers in air rather than in vacuum produces much less bubbles. For vacuum bonding, good bonding, such as high bonding strength and high bonding efficiency, can be achieved at temperatures as low as 300 °C. From the comparison between air wafer bonding and medium vacuum wafer bonding, it is obvious that medium vacuum annealing can improve the bonding strength and accelerate the bonding process. Based on the results observed, a qualitative mechanism of medium vacuum wafer bonding at low temperatures was proposed.


With the accelerating process of industrialization,a large number of agriculture land have been turned to industrial using land,which leads to affect the soil environment quality of the surroundings.By the method of partition sampling,the topsoil samples were collected from area of coal industrial park in Henan Province.The contents and pollution indices of soil Hg,Cd,Zn,As,Pb and Cr were analyzed.The heavy metal contents of surrounding soil were analyzed and compared to indicate the potential factors or trend of soil environmental pollution.The results showed that the single pollution index and the Nemerow pollution index of six heavy metals in soil in coal industry park were in the security level.But the average contents were higher than the surroundings.The potential heavy metal pollution risk factor might be Hg,followed by Cd,Zn,As,Pb and Cr.As the spatial distribution,except for Cr,other tested heavy metal contents decreased with the increase of distance from the industrial park.Finally,some reasonable suggestions for soil pollution prevention were put forward according to the results of this research.


The scalable parallel implementation, targeting SMP and/or multicore architectures, of dense linear algebra libraries is analyzed. Using the LU factorization as a case study, it is shown that an algorithm-by-blocks exposes a higher degree of parallelism than traditional implementations based on multithreaded BIAS. The implementation of this algorithm using the SuperMatrix runtime system is discussed and the scalability of the solution is demonstrated on two different platforms with 16 processors.


There are many possible ways to perform the attitude control of a quadcopter and, recently, the subject of event-triggered control has become relevant in the scientic community. This thesis deals w ...


Transfer alignment is the main method to solve the problem of initial alignment for airlaunching missiles on moving base. Actually, it is a data matching process of the aircraft INS and the INS on air-launching missiles. The matching methods using usually include the velocity matching, the position matching, the attitude matching, the angular rate matching, the acceleration matching and the combined matching. The performance of transfer alignment is debased because of the uncertainty in dynamic environment, so the transfer alignment on moving base is a dii cult point for research all the time. This paper analyzed the dynamic characteristics of the aircraft, coni rmed the main interference source of transfer alignment and researched on the influence mechanism of different dynamic interference factors on the ef ect of dif erent transfer alignment matching methods. The study can provide references for the targeted design of transfer alignment method.


James Hammond and co-authors report from a BGA meeting on how advances in instrumentation are opening up opportunities for dense, large-scale deployments of seismometers on land and in the oceans.


K. Inhibition of steroid-induced prostatic hyperplasia in rats by treatment with anti-androgen (TZP-4238). Endocr. J. 1993; 40: 479–88. 19 Persson K, Andersson KE. Non-adrenergic, non-cholinergic relaxation and levels of cyclic nucleotides in rabbit lower urinary tract. Eur. J. Pharmacol. 1994; 268: 159–67. 20 Dokita S, Morgan WR, Wheeler MA, Yoshida M, Latifpour J, Weiss RM. NG-nitro-L-arginine inhibits non-adrenergic, non-cholinergic relaxation in rabbit urethral smooth muscle. Life Sci. 1991; 48: 2429–36. 21 Doh H, Shin CY, Son M et al. Mechanism of erectogenic effect of the selective phosphodiesterase type 5 inhibitor, DA-8159. Arch. Pharm. Res. 2002; 25: 873–8. 22 Choi SM, Kim JE, Kang KK. Chronic treatment of DA-8159, a new phosphodiesterase type V inhibitor, attenuates endothelial dysfunction in SHR-SP. Life Sci. 2006; 78: 1211–16. 23 Kang KK, Yu JY, Yoo M, Kwon JW. The effect of DA-8159, a novel PDE5 inhibitor, on erectile function in the rat model of hypercholesterolemic erectile dysfunction. Int. J. Impot. Res. 2005; 17: 409–16. 24 Ying J, Yao D, Jiang Y, Ren X, Xu M. The positive effect of sildenafil on LUTS from BPH while treating ED. Zhonghua Nan Ke Xue 2004; 10: 681–3. 25 Hopps CV, Mulhall JP. Assessment of the impact of sildenafil citrate on lower urinary tract symptoms (LUTS) in men with erectile dysfunction (ED). J. Urol. 2003; 169 (Suppl 4): 375. 26 Roehrborn CG. Lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction, and phosphodiesterase-5 inhibitor. Rev. Urol. 2004; 6: 121–7. 27 Bahng MY, Kang KK, Ahn BO et al. Tolerance and pharmacokinetics of single-dose DA-8159 in healthy male. Int. J. Impot. Res. 2002; 14(S3): S101. 28 Amakye D, Ward J, Bryson S, Han K. DA-8159-phase I studies to investigate the safety and pharmacokinetics in healthy male Caucasian subjects. Clin. Pharmacol. Ther. 2004; 75: 86. 29 Padma-Nathan H, Paick JS, Ahn BO, Kang KK, Bahng MY, Kim WB. Phase 1, double-blind , placebo-controlled study in healthy male subjects to investigate the safety, tolerability, and pharmacokinetics of DA-8159. J. Urol. 2004;171 ( 4 ): S234.


Joining chain (J‐chain) is well known as an integrated component of dimeric immunoglobulin A (IgA) and pentameric IgM. We show here that the J‐chain protein is also expressed in a subset of CD11c+ dendritic cells (DC) in C57BL/6 mice. J‐chain knockout mice (J−/− mice) had a reduced fraction of CD4−/CD8α+ and mPDCA‐1+ DC in the spleen. J−/− mice also had reduced levels of RNA for the immunoregulatory enzyme indoleamine 2,3‐dioxygenase (IDO) in the spleen. Furthermore, in lymph nodes from C57BL/6 mice the majority of J‐chain‐expressing CD11c+ cells also expressed IDO, while the number of IDO‐expressing cells in lymph nodes and the amount of IDO protein in splenic CD11c+ cells were reduced in J−/− mice. Also, J−/− mice had a lower ratio of kynurenine/tryptophan in serum compared to C57BL/6 mice, indicating a lower overall IDO activity in J−/− mice. We also show that J−/− mice are less susceptible to tolerance induction than C57BL/6 mice. In conclusion, our data show that J‐chain protein is expressed outside the B‐cell compartment in a subset of immunoregulatory DC that are compromised in animals that cannot express J‐chain.


In order to verify the correction of the friction factor fractal model of the end faces for mechanical seals, some tests for mechanical seal were conducted on the self-designed mechanical seal testing device. Experimental sealed medium was 15°C water. A series of experimental data of friction factor were obtained under different spring pressures and sealed fluid pressures as well as at various rotating speeds. Compared the theoretical calculation data with those of experimental, the results show that the friction factor variation of theoretical was the same as those of experimental with the change of the working parameters, the relative error decreased with the increase of rotating speed and sealed fluid pressure, and the maximum relative error was less than 5.5% when the rotating speed reached the normal working speed of 2900 rpm.


Structural shifts caused by the expansion of "green" convergent technologies significantly enhance the ecological convergence of the economies in the countries in which they determine the exit to the trajectory of sustainable development. At the same time, in an economy where the commercialization and diffusion of green technologies is constrained by structural problems, the prerequisites for environmental divergence are formed, which can finally consolidate technological lag and a long-term trend of environmental degradation. The transition from environmental divergence to convergence should be carried out in a system of convergentoriented structural policy. It presents a three-level complex: targeted changes in the reproductive structure, the proportion of production factors (the first level); impact on the sectoral, technological, market-competitive, social structures of the economy (the second level), development of research, production and financial infrastructure for the commercialization and transfer of "green" technologies (the third level).


ABSTRACT Resilient Modulus (Mr) is an important material property for pavement design and evaluation. The Mr values can be estimated in the laboratory by measuring material's response under simulated field loading conditions. It can also be determined from nondestructive tests such as the falling weight deflectometer. Some previous studies have shown, however, that the Mr values determined from laboratory testing can differ significantly from that determined from the backcalculated resilient moduli using FWD data. This paper presents the results of a site-specific comparison of the Mr values determined through laboratory testing and backcalculation of FWD data. Both laboratory and FWD data are related to an instrumented pavement section on I-35 in central Oklahoma. Unlike most previous studies that focused on FWD testing on the top of asphalt concrete, in the present study FWD tests are conducted on different layers namely, natural subgrade, stabilized subgrade, aggregate base and asphalt concrete. The study indicated increase in backcalculated Mr values due to the construction of overlying layers. For natural subgrade and aggregate base layer, backcalculated Mr values were found higher than corresponding laboratory determined Mr values. In addition, FWD tests were also performed on top of the asphalt strain gauges and earth pressure cells and strains and pressure data were collected simultaneously. A comparison of the pavement response between the predictions from a multilayer elastic program, KENPAVE, and the in-situ sensors was made.


Background:  Onychomycosis is a fungal infection of the nails, which manifested as nail discoloration, thickening, and detachment from the nail bed. It is not life-threatening, however inappropriate treatment of onychomycosis might lead to complications and affect the patient's quality of life; making the management of the disease a challenge for clinicians. Objective:  Investigate the efficacy of pulse-dosed oral terbinafine combined with topical 8% ciclopirox olamine to treat onychomycosis. Methods:  Literature search was performed in Pubmed and Cochrane databases using the keywords  'combination' AND 'oral terbinafine' AND 'ciclopirox' AND 'onychomycosis treatment'  along with their synonyms and related terms. Results and Discussion:  After critical appraisal, studies by Avner et al. and Jaiswal et al. found to be valid, important, and applicable to the patient. The first study found that oral terbinafine combined with topical 8%  ciclopirox olamine is more effective and safe compared to terbinafine as a monotherapy (p 0.05). Conclusions:  Oral terbinafine combined with topical 8% ciclopirox olamine is more effective than monotherapy, despite statistical irrelevance in one of the studies appraised. Further studies are needed to support the implementation of combination therapy. Keywords: ciclopirox, efficacy, combination, onychomycosis, terbinafine


ABSTRACT We analyse the association between age at tertiary graduation and outcomes of the first phase of the working career in Italy by using a rich longitudinal dataset built merging EU-SILC survey data with individual administrative records on working careers. Labour market outcomes is observed at the entry and along the 10-year period from graduation. No large differences in weekly and annual earnings and worked weeks emerge across individuals who attained the degree at different ages, thus showing a negligible direct penalisation related to graduating not at typical age in Italy. In particular, no statistically significant associations emerge as concerns the link between age at graduation and total earnings obtained during the 10 years from graduation.


Excerpt To the editor: The recent brief communication by Dr. Harold Conn concerning "Sudden Scrotal Edema in Cirrhosis" which appeared in the June 1971 issue of the ANNALSbrought to mind an interes...


Utilizing nanotechnology, proprietary chemistry, and microfluidics, innovative firms are developing biochips and instrument systems that enable high-speed automated biomedical sequencing. Incom Inc. presents development results on five novel biochip technologies based on FiberOptic MicroSlide and microcapillary technology. FiberOptic MicroSlides are fiber optic interrogated (FOI) biochips made up of millions of fused optical fibers, and are uniquely suited as a platform for microarray applications. FiberOptic MicroSlides (henceforth referred to as "MicroSlides" or "slides" in this paper) act as a 'zero thickness substrate' transmitting optical signals from top to bottom without spreading, so that fluorescent or luminescent activity on the surface or within a well can be directly coupled to a CCD device without additional optics. In contrast to bulk optics, the slides are compact and have excellent light-gathering power. They are an alternative to conventional microscope slides for applications involving moderate-resolution bottom viewing (inverted microscopy). The surface of the MicroSlides can be etched or patterned with a permanent polymer to form microwell arrays, or microfluidic structures suitable for genomic and proteomic analysis, cell migration studies and other applications. Low-cost microcapillary array plates have also been developed. These plates act as microscopic test tubes, which enable picoliter reactions to be detected, counted and analyzed. Progress in developing large area (300 mm X 300 mm) arrays with up to 100 million capillaries, and diameter / length aspect ratios up to 10,000: 1 is presented. Results demonstrate negligible optical cross talk between capillaries, resulting in improved signal-to-noise ratios while minimizing false hits.


Determining the direction of causal influence from observational data only is essential in many applications, such as the reconstruction of genetic networks from microarray data. As opposed to many probabilistic network inference algorithms which were designed to induce just statistical models of the data, Conditional Independence (CI) based algorithms are theoretically able to infer true causal models from observational data only. But unfortunately, the small sample sizes available from current microarray experiments render the determination of causal direction highly inaccurate. Here we show that this essential aspect of CI-based algorithms can be significantly improved by double-checking certain key statistical tests and by reconciling potential inconsistencies using a simple constraint propagation scheme.


Earlier studies have shown that Australian women are concentrated in a narrow range of occupations and that although occupational segregation has declined during the 20th century, the rate of decline is diminishing. This study uses census data from 1891 to 1981 to analyze the sources of changes in the Duncan and Duncan segregational index. It distinguishes changes in the index due to shifts in the occupational mix of the economy, and shifts in the sex composition within specific occupations. Both effects contributed to the general decline in segregation although the composition effect was quantitatively more important.


Aza‐peptides have been used as tools for studying SARs in programs aimed at drug discovery and chemical biology. Protected aza‐dipeptides were synthesized by a solution‐phase submonomer approach featuring alkylation of N‐terminal benzophenone semicarbazone aza‐Gly‐Xaa dipeptides using different alkyl halides in the presence of potassium tert‐butoxide as base. Benzophenone protected aza‐dipeptide tert‐butyl ester 31c was selectively deprotected at the C‐terminal ester or N‐terminal hydrazone to afford, respectively, aza‐dipeptide acid and amine building blocks 36c and 40c, which were introduced into longer aza‐peptides. Alternatively, removal of the benzophenone semicarbazone protection from aza‐dipeptide methyl esters 29a–c led to intramolecular cyclization to produce aza‐DKPs 39a–c. In light of the importance of aza‐peptides and DKPs as therapeutic agents and probes of biological processes, this diversity‐oriented solution‐phase approach may provide useful tools for studying peptide science. Copyright © 2010 European Peptide Society and John Wiley & Sons, Ltd.


Objective The purpose of this study was to analyze the trends by year, country, institution, journal, reference and keyword in publications on the autophagy of pancreatic cancer (PC) and to predict future research hotspots. Methods The Web of Science Core Collection was used to search for publications. The contributions of various countries/regions, institutes, authors, identified research hotspots, and promising future trends were analyzed using the VOSviewer1.6.16 and CiteSpace6.6.R2 programs. We also summarized autophagy relevant clinical trials of PC. Results A total of 1293 papers on the autophagy of PC published between 2013 and 2023 were included in the study. The average number of citations per article was 33.76. The China had the most publications, followed by USA, and a total of 50 influential articles were identified through co-citation analysis. Clustering analysis revealed clusters of keywords: metabolic reprogramming and ER stress, mTOR-mediated apoptosis, extracellular trap as the most concerned clusters. The co-occurrence cluster analysis showed pancreatic stellate cell, autophagy-dependent ferroptosis, autophagy-related pathway, metabolic rewiring, on-coding RNA as the highly concerned research topics in recently. Conclusion The number of publications and research interest have generally increased over the past few years. The China and USA have made prominent contributions to the study of the autophagy of PC. The current research hotspots mainly focus not only on the related modulation, metabolic reprogramming, ferroptosis of tumor cells themselves, but also on tumor microenvironments such as autophagy associated pancreatic stellate cells and new treatments targeting autophagy.


SUMMARY Investigations of the biological properties of tick-borne encephalitis viruses immediately after isolation from naturally infected Ixodes persulcatus from Western Siberia has revealed their different pathogenicity for monkeys and mice. Strains highly pathogenic for mice on extraneural inoculation and for rhesus monkeys on intracerebral inoculation have been isolated, but also strains with a low extraneural pathogenicity for mice and a complete non-pathogenicity or a mild pathogenicity for monkeys on intracerebral inoculation. The viruses have been classified into three main groups by their virulence for mice and monkeys, and their ability to grow in tissue culture at 40° C. and the findings are summarized in Table 6. Group I included viruses highly virulent for mice by any route of inoculation, which caused fatal paralytic disease in monkeys, and which grew well in chick embryo culture at 40° C. Group II strains also had a high virulence for mice, but in monkeys caused milder disease with a peculiar clinical course indicative of primary damage to the cerebellum. About half of the infected monkeys recovered completely or with mild sequelae (ataxia, pareses of the limbs). This group grew moderately well in chick embryo cultures at 40° C. Groups I and III differed essentially in their virulence for mice by subcutaneous inoculation, and virulence for monkeys decreased distinctly with transition from group I to group III. Group III strains showed a lower reproduction rate at 40° C. In chick embryo culture than group I. Groups I and II showed good correlation between extraneural pathogenicity for mice, pathogenicity for monkeys by IC inoculation, and growth rate in chick embryo cultures at 40° C. Group I strains were isolated chiefly from foci with a high TBE morbidity and the strains of groups II and III in foci with sporadic cases. It is, however, highly probable that in any tick-borne encephalitis focus several variant strains of differing virulence exist. Recent experience of vaccinating volunteers with naturally attenuated group III strains suggests that safe and effective live vaccines can be developed against tick-borne encephalitis. Vaccines against many other arbovirus diseases can probably also be derived from naturally occurring strains of virus isolated from arthropods in areas of low disease but high infection rate. This approach looks more promising than the usual approach of attempting to develop attenuated strains from highly virulent strains.


Aluminized melt-cast TNT and PBX (cast/pressed) based compositions have been widely studied and used in different warheads for various applications,such as air blast, underwater blast, thermobaric effects, etc. Tungsten (W) based cast PBX formulations are the least reported in the literature. We have partially replaced RDX or HMX in the control PBX formulation with 15 to 25% W powder and investigated the effect of this on the ease of processing, density, sensitivity, mechanical properties and explosive performance. The viscosity was improved from 9 to 3 kPoise, and the density by about 12 to 25% on the addition of W powder to the PBX formulations. The sensitivity to impact for the RDX/Wand HMX/W based PBX formulations was improved by 12 to 37%. The reinforcing effect of the W powder caused an increase in hardness (Shore A) by 16 to 45%. A decreasing trend in the velocity of detonation (VOD) was observed because of the replacement of the nitramine content (RDX/HMX) with W powder. The approximate detonation pressure of RDX/W/HTPB (65/20/15), roughly calculated by the Kamlet-Jacobs method, is better than the other tungsten based formulations investigated.


We investigated the relations between swimming motions and flow fields around plankton that is a larva of brine-shrimp (Artemia salina) and jellyfish (Aurelia aurita). These move in low Reynolds numbers by flapping motion in common. We recorded motions and flow by using a high speed CCD camera, and analyzed by a motion analysis and PIV method. We observed vortex pairs in each case as a result of power stroke and recovery stroke of pitching motion. Force acting on the body was estimated by measured acceleration of the body. Mechanism of generation of thrust force related to vortex pairs by flapping motion in low Reynolds number environment was discussed in this paper.Copyright © 2007 by ASME


Background: HIV/AIDS emerged as one of the most important public health issues of the late twentieth and early twenty-first centuries and is now one of the leading causes of global morbidity and mortality. The objective of this study was to determine quality of life of people living with HIV/AIDS by using different Domain Scores. Methods: This was a Bi-centric qualitative cross-sectional study, which was conducted in the three phases, by using standard, validated questionnaires used in WHOQOL HIV –BREF. Findings: Correlation of mean score of overall quality of life and general health score were statistically significant for gender, occupation, per capita income, age, education, marital status, current illness, treatment, CD4 count, HIV status and duration of disease. Correlation coefficient of different domains viz. physical health, psychological health, leave of independence, social relationship, environment, personal belief and spirituality, with overall quality of life score and general health score ranged from + 0.4 to + 0.7. 1.4. Conclusions Although overall quality of life was affected by different socio-demographic determinants, CD4 count, treatment, HIV status and duration of disease, it was contributed by six domain viz. Physical, Psychological, Level of independence, Social relationship, Environment and Spirituality / religion/ personal belief. So, a different approach under integrated program is required to strengthen the most affected domain in above variable to improve overall quality of life of people living with HIV/AIDS.


Epidemic of obesity is a serious problem. According to CDC statistics for the United States population about 35.7% of adults and approximately 17% of children and adolescents (2-19 years old) were obese in 2009-2010. Numerous epidemiological studies demonstrated that obesity is a risk factor for multiple diseases like cancer and cardiovascular. The various weight loss and weight control programs were conducted in recent years and demonstrated effectiveness for the short period of time, yet, the majority of participants re-gained weight sooner or later. Such process of loss and re-gain weight is called weight cycling, and the prevalence of weight cyclers is growing in the United States. The phenomenon of weight cycling is less studied. Some research for association of weight cycling and morbidity and mortality was conducted in 90 th of last century and demonstrated controversial results. National Task Force on the Prevention and Treatment of Obesity summarized the forty three (43) English-language articles that evaluated the effects of weight cycling on humans or animals in studies done from 1966 through 1994. Authors concluded that most studies demonstrated the association between body weight cycling and mortality and morbidity. Nevertheless, the biggest problem to drive solid conclusion was the lack of standardized definition of weight cycling, and research slowed down in this area. This paper provides a brief review of proposed methodological approaches for weight cycling. The most critical key elements of weight cycling like the magnitude of gain/loss, duration and the frequencies-number of cycles are suggested for unified algorithm. User-friendly SAS® V9.12 macro that is flexible in choosing parameters and transparent in each step of calculation determines weight cyclers. The author is convinced that this paper and proposed algorithm supported by SAS® macro can expedite the research of harm and/or benefit of weight cycling on the health of million people.


Objective:To explore clinical features and operative method of the carcinoma of neck of gallbladder.Methods:19 cases of the carcinoma of neck of gallbladder diagnosed from June 1982 to June 2000 were retrospectively analyzed.Results:The rates lymphatic metastasis and bile duct infiltration of the carcinoma of neck of gallbladder are higher than those of carcinoma of gallbladder,but hepatic metastasis rate is lower.Conclusion:The clinical manifestation and treatment in patients with carcinoma of neck of gallbladder may be different from carcinoma of gallbladder.


We report a simple preparation of surface enhanced Raman spectroscopy (SERS) substrates with gold concave nanocubes of different sizes, deposited onto aluminum slides. The SERS substrates were characterized using 4-Aminothiophenol. Resulting in that the substrate prepared with 55 nm nanocubes exhibits the higher analytical enhancement factor (AEF), 1.5 × 106. Moreover, the SERS substrates' performance was also evaluated for thiram detection using a series of water and tomato juice samples spiked with the pesticide. Our results show that the excellent performance of the substrate allows the detection of thiram with high sensitivity. The substrates were able to detect thiram with a limit of detection of 7 ppm and 14 ppm, respectively, in water and tomato juice. Our preliminary results open the possibility of using our methodology to detect diverse pollutants of interest.


A theoretical and experimental investigation of the fluid flow and heat transfer in a tube filled with porous body of high porosity (e95%) was carried out. A theoretical model of a circular tube with porous matrix attached at the channel wall and extended inward, toward the centerline was established. Through analyzing the flow in the porous matrix with the Brinkman extended Darcy equation and through including the effect of dispersion by adding the dispersion coefficient into the energy equation, the theoretical solution of velocity distribution and temperature fields were obtained. The experimental results show that relatively good agreement has been found between the theoretical solution and the experimental data in laminar region. This prove that theoretical model can be used to analyze the laminar flow and heat transfer in the tube with porous body, and this model can provide a theoretical basis for various porous enhanced tubes by further refinements and improvements.


ix Executive Summary 1 1.0 Introduction 4 1.1 Conventional View of DR – A Resource for Extreme Events 5 1.2 Expansive View of DR – Market Efficiency from Continuous Balancing of Demand and Supply 6 1.3 Summary of Views 7 1.4 Organization of Report 8 2.0 Problem Statement 10 3.0 DR Framework Benefits and Costs 14 3.1 Potential Benefits of Demand Response 14 3.1.1 Direct Financial Category 16 3.1.2 Pricing Category 16 3.1.3 Risk Management and Reliability Category – Event and Financial Risks ...... 18 3.1.4 Market Efficiency Category 19 3.1.5 Lower Cost Electric System & Service Category 21 3.1.6 Customer Service Category 22 3.1.7 Environmental Category 23 3.2 Potential Costs of Demand Response Investment 23 3.2.1 Initial Implementation Costs (fixed costs) 23 3.2.2 Ongoing Operating Costs (variable costs) 24 3.3 Overlay of Benefits and Costs by Stakeholder 24


Based on the slipping phenomenon when impregnated diamond bits drill weak abrasive formation or under low drilling pressure, a new thought of adding pore-forming agent to the bits matrix to weak its wear resistance is presented to improve bits' self-sharpening and drilling efficiency. The structure analysis of pore-forming agents show that both type A and type B pore-forming agent have pore formation function when they are eroded by drilling fluid and grinded by the rock, and type A pore-forming agent has better mechanical property because of close packing during hot-pressing. The performance test results indicate that the mechanical properties decrease with adding the pore-forming agents, while the segments containing the type A pore-forming agent decrease less than that of containing type B agent. The mechanical properties decrease a little when the content of the pore-forming agent is under 30%. The drilling rate of the bits increases significantly after the type A pore-forming agent is added, which can increase 1.4 times when the content of the pore-forming agent reach 30%. The condition of the segments' crown demonstrates that the pores uniformly distribute in crown of the segments containing the type A pore-forming agent having pore function. The analysis of the bits' self-sharpening by adding pore-forming agent shows that enhancing the roughness of the bit's crown can weak the diamond-setting ability of the bit matrix and improve the drilling efficiency.


Order-dispatching strategy is fundamental for online ride-hailing systems in three major ways. First, it should be capable of effectively matching hundreds of orders to thousands of vehicles in less than 1 min, whereas both orders and vehicles are geographically widely distributed. Second, it should decide how to fairly allocate profit among participators. Third, it should unify interests of present and future. Conflicts always exist within the three objectives. We observe that the system is dynamically balanced during fine-tuned time intervals. Based on this observation, we propose a novel dispatching strategy capable of juggling the three objectives. By applying optimal transport theory, we demonstrate that, under appropriate presumptions, this dispatching strategy is ruled by the optimal transport plan realizing the Wasserstein distance between distributions of orders and vehicles. Furthermore, we develop a kit of methodological and algorithmic tools which has substantial and sensible advantages in characterizing and optimizing the system.


As with the constantly development of globalization, different countries and regions have been closely linked. The flow of international capital, technology, product and labor creates new chance for the conflicts and blends of diverse cultures. In such a background, individuals' creativity plays a critical role in the development of itself and enterprises. An increasing number of researches have focused on how to convert culture's similarity and differences to multiple culture resource advantage, hence enhancing organizational innovation and development. This paper presents a framework that integrates and reinterprets current research in cross-culture and creativity. The framework also serves to identify areas that need further thinking and can be used as a template for those who want to have a whole picture of cross-culture and creativity.


The author presents the political analysis of issues and prospects of Russian territorial administration in terms of the scenario approach. Particular attention is paid to the correlation between factors and mechanisms of the federal and regional levels. Key elements of the active and passive scenarios for the situation development in the studied field are defined.


The present invention discloses a pinned photodiode having increased electron capacity of pinned and a method for forming a photodiode. The present invention provides a pinned photodiode structure, comprising a substrate base, over which the first layer of semiconductor material. Providing a first conductivity type base layer, wherein the base layer of the first conductivity type doped base layer on the substrate or the substrate base. At least one doped region of the second conductivity type located below a surface of the first layer, and extends to form a first junction with the base layer. A first conductivity type doped surface layer on at least one region of the second conductivity type, and at least one second conductivity type region forming the second junction.


Marine insurance policy protects the insured the risks encountered in maritime adventure. It commencement is reflected in the policy which specifies the particular date and time. Commencement of risk in marine insurance policy is very crucial. The commencement and duration of risk varies according to the type of policy undertaken by the insured. The insured can claim the damages only if the conditions and warranties attached to the policy is fulfilled. However, there are certain exceptions when deviation is permitted and the insured can claim the losses from the insurer which he had incurred during the maritime adventure.


This paper describes the application of the phase monopulse DOA estimation algorithm, using a new concept of sparse array called Vertigo. This novel element distribution is based on a transformation of a generic regular lattice, introduced in [1], which aims at grating lobe suppression. This paper demonstrates that the Elevation and Azimuth main lobes are not affected by the aperiodic antenna element position. Furthermore, the Vertigo distribution avoids the ambiguity in the angular monopulse estimation — due to the grating lobes in a regular lattice — without affecting the angular estimate accuracy.


In image-guided procedures high-contrast objects often appear in the imaging field-of-view for the purpose of guiding treatment (e.g., markers intended to localize the target) or delivering treatment (e.g., surgical tools, or in the case of brachytherapy, radioactive seeds). In cone-beam CT reconstructions, these high-contrast objects cause severe streak artifacts, CT number inaccuracy and loss of soft-tissue visibility. We have developed an iterative approach by which high-contrast objects are localized in the 2-D projection set by re-projecting conspicuities from the first-pass 3-D reconstruction. The projection operator, which finds the unique mapping from the world coordinate system to the detector coordinate system for each view angle, is computed from a geometric calibration of the system. In each projection, a two-dimensional 2nd order Taylor series is used to interpolate over the high-contrast objects. The interpolated surface is further modified using a local noise estimate to completely mask the objects. The algorithm has been applied to remove artifacts resulting from a small number of gold fiducial markers in patients being imaged daily with cone-beam CT for guidance of prostate radiotherapy. The algorithm has also been applied to post-operative images of a prostate brachytherapy patient in which the number of seeds can exceed ~100. In each case, the method provides excellent attenuation of image artifact and restoration of soft-tissue visibility. Using a local voxel based metric it was shown that the 2nd order Taylor series with added noise performed best at removing the high-contrast objects from the reconstruction volume.


A method of pH control for a neutralization process made use of Artificial Neural Network (ANN) to enhance a PID control. This Neuro-PID controller trained ANN based on control errors. The performance of the Neuro-PID controller was studied and evaluated by simulation, and its performance was compared with that of the conventional PID controller during actual experimentation. The simulation results showed that the Neuro-PID controller controlled the pH at a desired setpoint with a better performance than the conventional PID controller. Thus, the Neuro-PID controller could be used as an effective alternative to conventional process control techniques in the nonlinear, rapidly changing pH system.


Herein we detail the discovery of a series of parthenolide dimers as activators of PKM2 and evaluation of their anti-GBM activities. The most promising compound 5 showed high potency to activate PKM2 with AC50 value of 15 nM, inhibited proliferation and metastasis, and induced apoptosis of GBM cells. Compound 5 could promote tetramer formation of PKM2 and reduce nucleus translocation of PKM2 in GBM cells while without influence on the expression of total PKM2, thereby inhibited STAT3 signal pathway in vitro and in vivo. PKM2 knockdown assay demonstrated that the anti-GBM effect of 5 mainly depended on the expression of PKM2 in vitro and in vivo. Compound 16, a prodrug of 5, markedly suppressed U118 tumor xenograft growth and reduced the weight of tumor. On the basis of these investigations, we propose that 16 might be considered as a promising lead compound for discovery of anti-GBM drug.


BACKGROUND AIM: N-terminal ubiquitination may play a role in p21 Cip1/ WAF1 degradation via proteasome-dependent proteolytic pathway.We studied the influence of adding a N-terminal flag tag on the stability of p21protein. MATERIAL AND METHODS: NIH3T3cell stably expressing flag-p21was set up by retrovirus pWB3flag-p21infection followed by Blasticidin selection.Half-life of p21protein was tested by western blot with rabbit polyclonal anti-p21antibody,and proteasome inhibitor MG-132was employed to test the role of proteasome pathway on the degradation of p21protein. RESULTS: Half-life of endogenous p21in NIH3T3cells was about30minutes,while the half-life of exogenous flag-p21fusion protein expressed in the same tested cells was obviously increased.Although MG-132significantly increased the amount of endogenous p21protein,there was no detectable change of flag-p21expression under the same condition. CONCLUSION: N-terminal ubiquitination gvas necessary for effective p21proteasome-dependent degradation.That adding flag tag at the amino acid termini may stabilize p21protein should be considered.


†International Maize and Wheat Improvement Center (CIMMYT) Climate EconomistSouth Asia, §International Maize and Wheat Improvement Center (CIMMYT) Agronomist CG Block, National Agricultural Science Center (NASC) Complex, DPS Marg, Pusa Campus, New Delhi 110012, India, ¶International Maize and Wheat Improvement Center (CIMMYT) Senior Agronomist CG Block, National Agricultural Science Center (NASC) Complex, DPS Marg, Pusa Campus, New Delhi 110012, India and §§International Maize and Wheat Improvement Center (CIMMYT) and Chaudhary Charan Singh Haryana Agricultural University Senior Agricultural Economist Chaudhary Charan Singh Haryana Agricultural University, Hisar-125 004, India


The details for optimizing gamma-ray measurement system for specific applications are not always well understood. The setup and operation of a system plays an important role in performance aspects such as maximizing detector lifetime, stability and minimizing the signal to noise ratio. In addition to system setup and operation, the effects of scintillation detector design and accompanying electronics (PMT) are discussed with respect to both gross counting and spectroscopy measurements in order to obtain reliable results. Data has been taken with various sodium iodide scintillation detectors to study system stability during transient such as power cycling and count rate fluctuations. These fluctuations may introduce substantial measurement uncertainty, and if not accounted for will propagate into an analyses. The above transients can also affect the detector lifetime, and if the system conditions are monitored properly, they can be used as a predictive tool for determining the useful life of a detector. Data is also presented to examine counting statistics in an overlapping spectrum as a function of spectral resolution and count rate. The objective is to determine the optimum counting time for the spectrum to reach a statistically stable shape. The data is reduced by examining the standard deviation of fitted Gaussian curves at ten second intervals. The result is a contour plat showing the time needed to reach stability, which increase with spectral resolution and decrease with a rising count rate.


Investors use many rules to make an investment decision. Many of the rules will be framed based on the trial and error method. This leads to the development of rules of thumb. Investors use these rules to make decisions in a complex and uncertain environments. But in reality, the investors' decisions are not rational. They are frequently influenced by psychological biases during investment decisions. One such bias is heuristic. This paper looks at these heuristics and its influence on investor's investment decisions. Heuristic variables such as representativeness, overconfidence, anchoring-adjustment, conservatisms and aversion to ambiguity were taken for this study. The multistage random sampling technique was used to collect the data from retail investors through the structured questionnaire. The data so collected was analysed quantitatively by using different statistical tools. Findings of this study suggest that investors are categorised based on the influence of heuristics as heuristic satisficing, heuristic bounded and heuristic unbounded. Further, based on the interactions of demographic and investment variables with the heuristics, investor's heuristic model has been framed and explained in this study.


A novel bovine astrovirus (BoAstV CH13/NeuroS1) has been associated with encephalitis in cattle in Europe and the USA. We retrospectively analyzed feedlot cattle with encephalitis of unknown etiology for this virus by in-situ hybridization. Results suggest that BoAstV CH13/NeuroS1 is a major cause of encephalitis in western Canadian feedlot cattle.


(57) Abstract: When using a dual cathode (9, 10) or double anode sputtering approach, the substrate (3) between the on the material of the insulating or conductive sputter deposition, the substrate (3) It discloses a method and apparatus for producing ion bombardment. The new electrical circuit center including the tap-ordered transformer (17), without any additional power source, controllable potential, it is possible to be applied to the substrate (3) with respect to the plasma potential. Also disclosed is, either by DC or high frequency AC, a approach that allows the use of a bias power supply (19 or 20), thereby, by alternating the impact of ions and electrons, the surface the makes it possible to continuously discharge.


This paper presents a PowerPoint presentation on the experiences of safety manager from the supplier perspective in a large Public Private Partnership (PPP) bid. It explores the issue of risk allocation and responsibility in PPP type procurements. It also discusses the issues associated with the bidding phase of large projects e.g. changes to fundamental safety standards. It concludes with some lessons learned.


Antonello da Messina's Palermo Annunciate (c. 1475) is usually construed as the equivalent of an icon. Relying on the iconography of the fifteenth-century Flemish Annunciation, Lorenzo Pericolo demonstrates that Antonello's panel must rather be interpreted as a "truncated" narrative in the form of an icon. From this premise, Pericolo also unveils the experimental charge of some pictorial devices used by Antonello, such as close-up, cut-in, and off-scene.


As seen from this trial program, psychiatric triage in the ED is potentially a very effective tool for improving the quality of mental health patient care. For a minimal investment in personnel, there is a potential for a major improvement in patient care, patient record documentation, interdepartmental relations, and financial reimbursement to the institution.


Summary Dual infection with endogenous herpes- and C-type viruses in cultured cells derived from normal guinea pigs as well as in single guinea pig cells, was observed. The guinea pig C-type virus was activated by maintenance of the cultured cells in BrdU containing medium and was detected in all guinea pigs tested, regardless of age, strain or source of animals. Manifestation of the herpesvirus required prolonged cultivation of the cells or co-cultivation with susceptible monolayer cultures. The herpesvirus isolation was age and strain dependent; it occurred most frequently in older inbred animals. Note added in proof: Guinea pig No. AD 185 showed GPHLV infection when tested at 11 mo. Furthermore, both GPHLV and C-type virus were observed in cultured spleen and/or kidney cells derived from leukemic guinea pigs.


The reaction of 1-methoxymethylindolylborates 2 with electrophiles in the presence of benzaldehyde enabled the novel construction of tri-substituted indoles in a 'one-pot' procedure.


To improve the fault diagnosis ability of the intelligent substation is very important for stable operation of power system and power supply reliability.One of the major problems that the power network fault diagnosis system faced is the fault classification problem.The existing classification algorithm has some shortcomings,such as the training samples imbalance,lack of consistent characteristics,weakness learning ability.The feature selection and learning strategies are added to Bayesian algorithm to propose an improved Bayesian fault classification algorithm.The experimental results show that the improved Bayesian algorithm can solve the fault classification problem effectively,and enhance the fault diagnosis capability of intelligent substation network.


Excerpt The Books of Trades attempt to give "Parents, Guardians and Trustees, as well as the Youths themselves, intended for Trades and Business, not only a general Description of almost all Handic...