Abstract Background SARS-CoV2 infection has been associated to a wide range of clinical scenarios, named COVID-19, ranging from acute respiratory distress syndrome to blood coagulation abnormalities and vascular manifestations related to hyper-inflammation. Recent focus has been addressed to study of microvascular alterations which may explain COVID-19 pathophysiology. Alterations in microvascular structure, identified as increased wall to lumen ratio (WLR) of retinal arterioles, have been extensively described in patients with cardiovascular diseases, such as hypertension or diabetes mellitus. Both inflammation and immune system dysregulation seem to play a role in the pathogenesis of these morphological changes. Purpose Aim of this study was to evaluate through Adaptive Optics microvascular differences of retinal arterioles between patients experienced COVID-19 and controls. Methods Patients were hospitalized between 28th February and 15th April at a Internal Medicine ward in a tertiary care hospital. All patients tested positive for a SARS-CoV-2 nasopharyngeal swab at admission and showed signs of pneumonia and respiratory insufficiency. Adaptive Optics, which allows a non-invasive evaluation of retinal arteriole structure, and blood chemistry exams were performed as part of follow up visits between 2 to 3 months after hospitalization. Baseline characteristics were collected through medical records. COVID-19 patients were compared to age- and sex-matched healthy subjects referred to our center between 2018 and 2019. Results A total of 80 patients were included in this study (of which 40 were COVID-19 patients). Apart from smoking habit, other baseline characteristics (sex, age, cardiovascular risk factors and main comorbidities) did not differ between the two groups. At follow up visit COVID-19 patients showed lower values for leukocytes (6.2 vs. 7.5x103/μL, p=0.015) and lymphocytes (1.9 vs. 2.8x103/μL, p=0.002). Creatinine values were higher in patients who suffered from COVID-19 (1.0 vs 0.8 mg/dl, p=0.004 – Figure 1, panel A). Adaptive Optics showed no differences in terms of internal lumen, wall thickness and WLR of retinal arterioles. However, the wall cross-sectional area (WCSA) was found to be higher in COVID-19 patients (p=0.039 – Figure 1, panel B). Hypertension significantly affected both WCSA and WLR between COVID-19 and healthy individuals, while diabetes only impacted on WLR (Figure 2). Conclusion Previous studies described the presence of leukopenia and lymphopenia during the acute phase of SARS-CoV2 infection. Our study demonstrates that these alterations persist several weeks after symptoms onset. Adaptive Optics showed microvascular alterations occurring in these patients: in particular, higher wall cross-sectional area of retinal arterioles were observed in patients after COVID-19 hospitalization, reflecting the complex pathogenic mechanisms which may explain the wide range of symptoms and clinical severity. Funding Acknowledgement Type of funding sources: None. Figure 1 Figure 2


In this paper,we give a new geometric explanation of the multipoint Newton-Raphson iteration. According to this explanation,we give a simple proof of its 4-order convergence and some related results. In addition, we conclude that the multipoint Newton-Raphson iteration is more efficient than the Olver iteration and the Newton iteration.


The abolition or reform of unfunded pensions will generally make members of a transitional generation worse-off, because of the "double burden" of funding their own retirement along with that of paying off the unfunded pension liability. Reform will also lower the time-path of interest rates, which will reduce both firms' costs of capital and the rates at which they discount their future profits. Each of these two effects will raise the present value of the gains from technological innovation. These may then cause an immediate supply-side response, which, in turn, may solve the double-burden problem. We demonstrate this possibility numerically in a simple overlapping-generations model. 1 This paper is part of the research project, "Social security initiatives and economic growth" under the Evolving Macroeconomy Programme, initated by the ESRC to which I am grateful for finance. Thanks are due to Mike Bleaney and Richard Disney for helpful comments, while the responsibility for any remaining shortcomings with the author. 2


BACKGROUND
Reperfusion of ischemic heart causes the generation of free radicals, and these radicals play an important role in post-ischemic tissue damage. These free radicals are removed by scavenger enzymes and antioxidants in the cell. In this study, erythrocyte catalase, glutathione peroxidase and glutathione reductase enzyme activities were determined in patients undergoing cardiopulmonary bypass.

METHODS

EXPERIMENTAL DESIGN
Blood samples were obtained from the coronary sinus of patients at the following times: 1) Before cardiopulmonary bypass, 2) Immediately after cardiopulmonary bypass, 3) Fifteen minutes after the second specimen, 4) Thirty minutes after the second specimen.

PATIENTS
this study was carried out on eleven patients undergoing open heart operation.

MEASURES
catalase, glutathione peroxidase and glutathione reductase enzyme activities were determined in these patients. RESULTS. Catalase activity was significantly decreased in the third and fourth groups as compared with the first group, which was also the control group (p<0.05). Glutathione reductase activity in the third group was significantly higher as compared with control group (p<0.001). However, there were no differences in glutathione peroxidase activity among control group and other three groups (p>0.05).

CONCLUSIONS
Our results indicate that the activities of antioxidant enzyme activities in erythrocytes are changed during the ischemia and reperfusion of the heart.


This paper describes the grinding optimization of a fragile,brittle tungsten polymetallic ore.According to the laboratory conditions test,the laboratory grinding conditions of filling rate of 45 %,grinding time of 4 min,grinding concentration of 67 %,ratio of speed 200 r/min,precision ball diameter: Φ50 ∶Φ40 ∶ Φ30 = 25 %∶25 %∶50 % were obtained.Then verified by precision experiments under the above conditions,the interval of 19~74 μm is the highest grade which is in line with the range of dissemination size and dissociation for tungsten ore,the interval of-10 μm metal distribution is decreased than that of the site.The characteristics of particle size and metal distribution of the grinding product are improved comprehensivly.


This paper proposes a simulator of EDLC, which realizes the performance equivalent to electric double-layer capacitors (EDLCs). The proposed simulator consists of an electrolytic capacitor and a two-quadrant chopper working as a current source. Its operation principle is described in the first place. The voltage dependence of capacitance of EDLCs is taken into account. The performance of the proposed EDLC simulator is verified by computer simulations.


Yunnan University was estabhshed in 1922 with its origianal name being privately - owned Donglu University. The establishment of the University took only five months. The homeland - loving returned overseas students, represented by Dongze, made a big contribution to the development of Yunnan's education of high learning.Dongze,Huaxiusheng,Heyao and Xiongqinglai,the four returned overseas students,who had pursued their studies in the United States and Europe,successively served as the presidents of the Univer- sity in the republican period.They strongly advocated the modern American and Eropean educational patterns during their terms and made the school develop into a University which was famous domestically and interna- tionally.During this process,the school went through four periods:the period of Privately-owned Donglu U- niversity,the period of Provincial Donglu University,the period of Yunnan Provincial University ard the peri- od of State-owned Yunnan University.Dongze and Heyao,the first and fourth presidents especially helped the University gain its dominant position.In 1946,Yunnan University was cited by the British Encyclopedia as one of China's most prestigious Universities.


The paper critically evaluates the results of the European Commission set in "An Aviation Strategy for Europe"of 2015 in the form of the Indicative Action Plan. Balancing accomplished vs unaccomplished tasks across the fields of Common Aviation Policy and the legal nature of the tasks, the paper discusses broader context of the Common Aviation Policy of the European Union in light of eventual institutional and fiscal reform.


AIM
This study aims to develop new nanoformulations of EGFR T790M targeted inhibitor AZD9291 and paclitaxel (PTX) for combination therapy of lung cancer.

MATERIALS & METHODS
We prepared and characterized PTX- and AZD9291-loaded disulfide cross-linking micelles (DCMs), and evaluate their combination effect and toxicity in vitro and in lung cancer-bearing mice.

RESULTS
Drug-loaded DCMs were relatively small in size, and possessed glutathione-responsive drug release. The combination of PTX-DCMs and AZD92921-DCMs exhibited strong synergistic effects in both cell line and in vivo without additional toxicity. Molecular studies demonstrated the synergistic modification in both IKB-α/NF-κB/Bcl-2 and EGFR/Akt pathways.

CONCLUSION
The combination of DCM-loaded AZD9291 and PTX could potentially offer more effective and less toxicity treatment options for lung cancer patients.


Background: In the area of evidence based medicine (EBM), biostatistics and epidemiology are considered as the main elements aiding the health professional to design a research study, understand the literature, and make decisions about patient care. Planners and policy-makers in the medical health science education institute need to apply research-based information to maintain and improve quality of teaching-learning processes. Methods: Eighteen until twenty-five medical doctors and health professionals from FM UMM, other universities and hospital, participated in this intervention, which consisted of four day workshop. We assessed the impact of this intervention through pre and post-workshop evaluations. Results: Significant result were obtained that showed the benefits of a biostatistics workshop in clinical research that can help medical doctors and health professionals to develop a conceptual understanding of statistical ideas and their applications to investigate problems of medical and health research (p = 0,0000). The results indicate that workshop approach can facilitate developing statistical knowledge and skills to solve medical and health research problems. Incorporating biostatistics into evidence based medicine practice and curriculum would pave new ways into research fields. MHS faculty should include more effective biostatistics training in their faculty development programs and curricula to successfully prepare educators and students for this important lifelong learning skill.


This article elaborates the necessity of constructing Broadcast Television network operator call-center system,as well as the hardware disposition,software function,management and the experience.Meantime it specifically discusses the establishment of repository and its application.


To the Editor:

Tumor necrosis factor-α (TNF-α) antagonists are highly effective drugs that have radically improved the functional outcomes and quality of life of many patients with inflammatory diseases. Although TNF-α antagonists are generally well tolerated and safe, the list of reported adverse events is growing steadily. The most common adverse events are infectious diseases including potentially severe infections due to intracellular organisms; allergic reactions including urticaria, rash, and stomatitis1; and biological autoimmune disorders. In addition, dermatological events not reported in premarketing clinical trials but seen in everyday rheumatologic and dermatology practice2 include acne3, eczema4,5, psoriasis6–8, vasculitis9, bullous lesions10,…


Communication Accommodation Theory (CAT) is a framework used to analyze and predict linguistic and behavioral adjustments within interpersonal communication. As computer-mediated communication (CMC) becomes more prevalent, applying this framework provides insight into interpersonal communication via a screen. Two studies explored CAT applied to CMC with participants observing linguistic adjustments in text-message screenshots. Results indicated that likability, empathy, gender, and textisms each play a role in how we perceive and interact with others during digital communications. Implications are discussed.


The purpose of this work is to analyse the influence of external factors on quantitative variables of Eurytemora affinis in water bodies of Kazakhstan. In 1997-2018, more than 150 water bodies located in various regions of the country were surveyed. The results obtained and analysis of the published literature showed that E. affinis primarily inhabits small shallow water bodies of Central and Eastern Kazakhstan. Populations from the North-Eastern Caspian Sea, originally identified as "Eurytemora affinis", could be attributed to the recently described species Eurytemora caspica. In the water bodies examined, E. affinis was found at water temperatures from 12 to 25°C and at salinities from 0.2 to 7.1 g/dm3. The highest abundance of Eurytemora was recorded at 21-22°C and a salinity of 1.0-3.0 g/dm3. The optimum temperature range in the water bodies examined in an extreme continental climate is higher than the values given for E. affinis in water bodies in a moderately temperate climate. The optimal TDS [Total Dissolved Solids] value (1.0-3.0 g/dm3) has shifted towards more truly fresh waters than was stated for E. affinis collected from the sea (6.2-8.2), and this was confirmed in experiments (from 3.0-10.0 to 10.0-15.0). In the majority of the examined water bodies of Kazakhstan, males dominated the Eurytemora populations. Male dominance in E. affinis populations might be due to the adverse effect of elevated temperature on the lifespan of females, and it was also connected with the level of toxic pollution of the water bodies. It seems that E. affinis endures a relatively high content of heavy metals, but it does not inhabit water bodies with very high toxic pollution. The revealed features of E. affinis' biology in Kazakhstan water bodies might be associated with both the heterogeneity of its populations from different parts of the range, and the existence of a complex of closely related species that at present is collectively named "Eurytemora affinis".


An evolved dual-band $2\times 1$ Microstrip Patch Array Antennas are designed with rectangular slot defected ground structure. The proposed antennas are used with two different substrates FR4 and RT Duroid 5880 and third one is the same shape with the half size of substrate and shape of the proposed antenna (${A}_{1}$ or ${A}_{2}$). The dimensions of the proposed antennas $({A}_{1},\ {A}_{2})$ and ${A}_{3}$ are taken as $(50\times 40\times 1.6)\ {mm}^{3}$ and $({25}\times {20}\times {1.6})\ {mm}^{{3}}$ respectively. The proposed antenna- ${A}_{{1}}$ resonate at 3 GHz and 17 GHz with the corresponding peak gain 2.76 dBi and 5.55 dBi and impedance bandwidth of 42.14% & 24.71% respectively. The proposed antenna- ${A}_{{2}}$ resonate at 4 GHz and 7 GHz with the corresponding peak gain 4.26 dBi and 5.52 dBi and impedance bandwidth of 30.77 % & 21.58% respectively. The proposed antenna- ${A}_{{3}}$ resonate at 5 GHz and 10 GHz with the corresponding peak gain 1.05 dBi and 1.50 dBi and impedance bandwidth of 7.84% & 10.84 % respectively. The applicability of all three proposed antenna depends on their resonance frequency, they are useful for S, C, X, K and ${K}_{{u}}$ -band and for next generation IOT devices and WLAN/Wi- Max for smart home applications. The designed has been simulated by HFSS v.13.0.


"Legal community" is the Sociology of Law is an important concept,scholars in the legal community and more will follow when the definition of the following two ways:as a social one of its main from the "natural" to "legal person" the process of conversion; Second,referring to Western countries,"the law of social movement." Construction of the legal community and scholars to promote the path of the law from the simple to the balance of the legal concepts of internalization,but only to follow the perspective of civil society in order to make the law of real people within,and promote the socialization of the law.


T HE current economical situation and specially the prediction of future events are en-couraging numerous H.R. professionals to think about the importance of having employ-ees committed with the company's business plan. To face the present economical break-down, a lot of companies are implementing dramatic downsizing processes as a fi rst step. However, for the second stage, the challenge for H.R. Management is to achieve workers aligned with the company's strategy through their commitment to the business project. Previous research related the organizational commitment to variables such as the job security (e.g. R OMZEK , 1985; S TEERS , 1977), job autonomy (e.g. B AKKER , D EMEROUTI and Euwema, 2005) and different H.R. practices (e.g. Pfeffer, 1994; W ALTON , 1985). In a sample composed by 458 workers from 16 private companies, the present study anal-yses the connection among commitment and autonomy, job security and four types of high quality H.R. practices. The results show that participation practices and autonomy at work are the variables with the highest predictive power on organizational commitment; the rest of H.R. practices (shared information, training and development and reward system), and the job security also showed signi fi cant relationships. These results allow concluding that the organizations which want to increase the commitment of their em-ployees have to develop stimulation programs considering this kind of variables, beyond the extrinsic considerations and/or guarantees of the continuance in the company. Abstract:


Malt containing high levels (up to 52 μg/kg) of ochratoxin A (OA) was prepared on a pilot scale by inoculating malting barley with live Penicillium verrucosum. This malt was then used for pilot brewing trials to determine the extent to which OA can survive the brewing process. Substantial losses, up to 40% of the OA in the grist, were observed during mashing, most probably by proteolytic degradation. Another 16% was eliminated with the spent grains. Some losses of OA occurred during fermentation, but these were less than those in mashing. Overall, between 13 and 32% of the OA present in the original grist survived into the beer.


Today, 50 years after the elucidation of the structure of DNA, high-performance computing, data management, and the Internet are making possible the large-scale industrialization of many aspects of biomedical research. The basic steps of identifying, purifying, and cloning a gene, followed by purification and characterization of the proteins coded for by that gene, have been automated and streamlined to a degree that no one could have predicted just ten years ago. Superimposed on this trend has been a rapid evolution in the design of large-scale computing infrastructure for bioinformatics. Coupled with explosive growth in the quantity of available bioinformatic data, these improvements are driving a migration from in vivo (observations of real life) to in vitro (test tube experimentation) to in silico (experimentation by computer simulation).


This study investigated whether dichloroacetate (DCA) decreases the reliance on substrate level phosphorylation during the transition from rest to moderate-intensity exercise in humans. Nine subjects cycled at ∼65% of maximal oxygen uptake (V˙o 2 max) after a saline or DCA (100 mg/kg body wt) infusion, with muscle biopsies taken at rest and at 30 s and 2 and 10 min of exercise. DCA infusion increased pyruvate dehydrogenase (PDH) activation at rest (4.0 ± 0.3 vs. 0.9 ± 0.1 mmol ⋅ kg wet wt-1 ⋅ min-1) and at 30 s (3.6 ± 0.2 vs. 2.5 ± 0.4 mmol ⋅ kg-1 ⋅ min-1) of exercise. As a result, acetyl-CoA (45.9 ± 5.9 vs. 11.3 ± 1.5 μmol/kg dry wt) and acetylcarnitine (13.1 ± 1.0 vs. 1.6 ± 0.3 mmol/kg dry wt) were markedly increased by DCA infusion at rest. These differences were maintained at 30 s and 2 min for both acetyl-CoA and acetylcarnitine. Resting muscle lactate and phosphocreatine (PCr) were not different between trials, but DCA infusion resulted in lower lactate accumulation throughout exercise, especially at 2 min (21.6 ± 3.1 vs. 44.6 ± 8.0 mmol/kg dry wt). PCr utilization in the initial 30 s (16.9 ± 0.4 vs. 31.7 ± 2.6 mmol/kg dry wt) and 2 min (27.8 ± 4.7 vs. 45.1 ± 2.6 mmol/kg dry wt) of exercise was decreased with DCA. This resulted in a lower accumulation of free inorganic phosphate at 30 s (25.4 ± 2.0 vs. 36.4 ± 2.8 mmol/kg dry wt) and 2 min (34.6 ± 4.7 vs. 50.5 ± 2.2 mmol/kg dry wt) with DCA and decreased glycogenolysis over 10 min. The data from this study support the hypothesis that increased provision of substrate by DCA infusion increases oxidative metabolism during the rest-to-work transition, resulting in decreased PCr utilization and an improved cellular energy state at the onset of exercise. The transitory improvement in energy state decreased glycogenolysis and lactate accumulation during moderate-intensity exercise.


Natural killer (NK) cells are innate immune cells that contain preformed cytotoxic granules and rapidly kill virally infected or transformed cells. However, they also possess features of adaptive immunity, as they can acquire antigen-specific memory and confer enhanced protection against secondary viral infection, although the transcriptional program underlying this feature has not been known. Mutations in the transcription factor interferon regulatory factor 8 (IRF8) have recently been reported to result in familial NK cell deficiency and severe viral infection in three unrelated families. Using a mouse model of selective deletion of IRF8 in NK cells, Adams and colleagues demonstrate that IRF8 is necessary for virus-specific NK cell expansion and consequent memory response to mouse cytomegalovirus (MCMV). The authors generated mice with selective deficiency of IRF8 in NK cells by crossing Irf8fl/fl mice with mice transgenic for Nkp46Cre/+. This complete deficiency did not hamper NK cell development, but did impair viral clearance and survival of MCMVinfected mice. MCMV recognition is mediated by the Ly49H receptor on NK cells ligating the viral glycoprotein m157 on infected cells. Transcriptome analysis revealed Irf8 to be one of the most upregulated genes after Ly49H engagement, undergoing rapid but transient expression. Its induction was partially dependent on interleukin 12/signal transducer and activator of transcription 4 (IL12/STAT4), but independent of type I and II interferons (IFNs) or IL-18. Chromatin precipitation sequencing and assay for transposase-accessible chromatin sequencing experiments suggested that STAT4 modulates the epigenetic landscape of the Irf8 promoter to induce IRF8 in activated NK cells. In terms of NK cell function, deficiency in Irf8 did not reduce MCMV-dependent NK cell production of IFN-γ and proinflammatory cytokines or cytotoxicity. Instead, in mixed bone marrow chimeras, it dramatically reduced MCMV-dependent NK cell proliferative bursts, resulting in fewer NK cells across various organs. Although the remaining NK cells were able to respond to a secondary infection, their lower numbers precluded the memory-like enhanced protection to secondary challenge. In contrast, Irf8 was not required for the maintenance of NK cell memory, as its inducible deletion after MCMV infection–driven NK cell expansion, using UbcCre-ERT2Irf8fl/fl mice, did not affect NK cell numbers. Moreover, the reduced expansion of Irf8-/NK cells was only apparent after viral infection and not for hapten-specific contact hypersensitivity responses, indicating that IRF8 is not required for signaling downstream of all NK receptors. SUMMARY AND ANALYSIS Watch LITERATURE


© 2016 Taylor & Francis Group, London. The two main obstacles to the commercial deployment of tidal turbines are cost and reliability. Behind both of these lies the ability of a turbine to withstand the hostile marine environment for long periods without failure or costly maintenance. Unsteadiness in the incoming flow seen by a tidal turbine causes large fluctuations in thrust and torque, which generate fatigue loads on the blade and drivetrain respectively and thus significantly reduce turbine lifespan. This paper will present the development of flow control devices to keep thrust and torque constant despite changes in flow speed. In particular, it will be shown that torque can be controlled using a small trip near the leading edge of the blade, and that thrust can be controlled viaa flap at the trailing edge. Data from a small-scale turbine will be used to show the effectiveness of both devices, and a reduction in unsteady loading of up to 75% will be demonstrated. This could translate into an order of magnitude increase in fatigue life.


This paper is a corpus linguistic analysis of 1000 random path-, road-, and way-instances from the British National Corpus. The aim is to show that both non-metaphorical and metaphorical instances ...


Remembering the 1914–18 War has a complex and contentious history in Ireland. Recent scholarship has re-examined the complexity of the Irish experience during this period, both by addressing the place of Irishmen in the Allied Forces and by retrieving the contribution of women towards the formation of the Irish Free State. However, the reinstatement of the female experience within the nationalist narrative has overlooked other female experiences of wartime in Ireland which were significantly different from those of their British counterparts. This essay examines an aspect of the 'Home Front' in Ireland when women's involvement in war industries, particularly in the Dublin munitions factories, are seen as crucial to the European war effort. Though the revolutionary, armed female volunteer is recognisably a figure of modernity, the female munitions worker, operating within the technological machinery of warfare, is also one. This essay explores the mobilization of women within the Irish war industries and suggests that there is still much work to be done in uncovering the extent of Irishwomen's contribution to the military war effort. Considering the complexities and contradictions of these parallel frameworks for modern Irish womanhood, this essay addresses how the Irish case adds important new dimensions to our understanding of the war's wide-ranging impacts on concepts of gender and the public roles of women that continue to resonate as the twentieth century unfolds.


A PNP-triggered SCR with improved trigger techniques is proposed for high-speed I/O ESD protection. By using these techniques, a high trigger voltage, VTRIG, for latch-up immunity during normal operating conditions, together with a low trigger voltage, Vt1, during ESD stress conditions, can be realized with simple design. Moreover, I/O circuits including the ESD protection are operable at a higher voltage than an on-chip core VDD. The PNP-triggered SCR is demonstrated in our 90 nm CMOS technology, suitable trigger voltages at both conditions (VTRIG = 4.0 V@125degC/ Vt1 = 2.0 V), and good ESD performances (HBM: 3500 V/ MM: 200 V) are achieved.


The European Medicines Agency approved ustekinumab for psoriasis treatment in adolescents (12–17 years) in 2015 (CADMUS trial), and children (6–11 years) in 2020. Interim results are reported from a post-authorization study (NCT03218488) evaluating the long-term safety profile of ustekinumab. This ongoing, prospective, observational, multicentre study enrolled patients (6–17 years) diagnosed with moderate-to-severe plaque psoriasis initiating ustekinumab. Clinical data and all adverse events (AEs) through approximately 54 months (data cut-off) are reported. Younger children (6–11 years) were included later in the study. Data are reported by age (younger cohort, 6–11; older cohort, 12–17). At data cut-off, 85 patients, 10 younger (median follow-up, 0.24 years) and 75 older (median follow-up, 1.69 years), had been enrolled. Ustekinumab therapy was discontinued in 11 (12.9%) patients, all from the older cohort. Overall, 50/85 (58.8%) patients reported 290 AEs and 27 (31.8%) reported 96 AEs considered related to ustekinumab. The most commonly reported AEs were nasopharyngitis (n = 8, 9.4%), fatigue (n = 7, 8.2%) and headache (n = 7, 8.2%). Most AEs were mild and did not result in treatment change. Nine (10.6%) patients reported 13 serious AEs; one (appendicitis) was considered related to ustekinumab. One younger patient reported two AEs considered related to ustekinumab, although neither was serious and therapy continued. No malignancies or deaths were reported in either cohort. These findings revealed no new safety concerns and are generally consistent with the known safety profile for ustekinumab in paediatric patients.


In order to acquire knowledge from databases, there have been proposed several methods of inductive learning, such as ID3 family and AQ family. These methods are applied to discover meaningful knowledge from large databases, and their usefulness is ensured. However, since there has been no formal approach proposed to treat these methods, efficiency of each method is only compared empirically. In this paper, we introduce matroid theory and rough sets to construct a common framework for empirical machine learning methods which induce the combination of attribute-value pairs from databases. Combination of the concepts of rough sets and matroid theory gives us an excellent set-theoretical framework and enables us to understand the differences and the similarities between these methods clearly. In this paper, we compare three classical methods, AQ, Pawlak's Consistent Rules and ID3. The results show that there exist the differences in algebraic structure between the former two and the latter and that this causes the differences between AQ and ID3.


To harden electronic systems against powerful electromagnetic pulse,a hybrid method which combined finite difference time domain(FDTD) and Simulation Program with Integrated Circuit Emphasis(SPICE) is provided.The effect mechanism of powerful electromagnetic pulse interaction with microstrip line is studied.The results show that the coupling of EMP on microstrip line has two different modes related to frequency,due to the complex structure of microstrip line.One is the surface wave coupling whose polarity is along the strip line,and the other is the slot coupling whose polarity is vertical to the strip line.The influence factors of transfer function under two coupling modes are very different.The study is significant to improving the defense ability of electronic system against EMP effects.


Two commercial non heat-treatable aluminium alloys (3004 and 5182) previously heavily cold-rolled have been submitted to in-plane shear tests in various directions with respect to the initial rolling direction. The macroscopic mechanical behaviour, the dislocations microstructure and the global crystallographic texture have been analysed. Both alloys presented before the shear tests similar geometrical characteristics: dislocation patterns, morphology of the granular structure and of the distribution of precipitates, crystallographic texture. They differed mainly by their solid solution, leading to a wavy slip character for the 3004 alloy and to a planar slip character for the 5182 alloy. The shear stress-shear strain curves were significantly different for the two alloys. In 3004 alloy, a stress saturation occured after about ten percent of strain, whereas the 5182 alloy appeared harder, with a positive hardening until the maximum stress, obtained after more than 40%. In both alloys, the ductility during shear test was hardly dependent on the direction α of shear with respect to the initial rolling direction. Shear strains larger that 100% could be obtained for α = 0° in 3004 and for α = 0°-15° and 90°-105° in 5182. Fracture occurred very early for the other α values, and these features was correlated to the development of shear bands in the gauge length from the corners of the samples. The spatial distribution of the shear bands was sharply localised in case of low ductility, whereas diffuse spreading of shear banding permitted high ductility. The T.E.M. observations showed elongated cells in the shear direction in 3004 alloy, and, after sufficient strain, microbands formation in 5182 alloy, consistently with the expected slip character. However, inside the shear bands, similar microstructure composed of highly elongated cells or bundles of microbands was observed in both alloys. The global crystallographic texture evolution was low in 3004 alloy due to the low ductility except for α = 0°, and to the partly stability of the textured for α = 0°. In 5182 alloy, more noticeable texture changes were pointed out, but the cases of large ductility corresponded to initial textures containing large volume fraction of stable torsion components, or when these components are easily obtained during shear.


Silk/cotton fabrics bear charming characteristics such as soft luster,delicate feel,excellent moisture sorption capacity,nice air permeability and draping property.Therefore,they are a kind of high quality textile material most favored among consumers.However,silk/cotton fabrics have also an obvious shortcoming,that is,the low wet crease recovery angle,which makes the fabric apt to crease during family washing or in a moist state.A study is made on the processing of silk/cotton fabrics with citric acid finishing agent so as to improve the crease resistance property.A discussion is held on the processing parameters which are likely to affect the crease resistance finishing of silk/cotton,such as dosage of finishing agent,baking temperature,baking time,variety and dosage of catalyst and so on.By testing crease recovery angle of fabrics under different finishing conditions,optimal finishing technology is obtained.


Qhis work by the distinguished scholar and performer of Arab music presents a collection of English translations and commentaries on medieval Arabic writings on musical rhythm. Representing the culmination of more than two decades of research on this subject, it expands the chapter on rhythm in Sawa's study Music Performance Practice in the Early 'Abbasid Era, 132-320 AH / 750-932 AD (The Institute of Mediaeval Music, Ottawa, 2004) to cover a wider range of literary sources within a more extensive historical period, from the early centuries of Islam to the Umayyad and early 'Abbasid era. Written mainly in Baghdad and reflecting performance practice in cultural centres of the Arab caliphate, these sources are diverse in scope and provenance, ranging from quotations of early musicians in later theoretical writings and belles-lettres to specialised treatises on rhythm. Here they are taken to represent two strands of medieval knowledge on rhythm (iqa'), examined in the two parts of the work: that of "practitioners," composers and performers, notably the celebrated musician Ishaq al-Mawsili (d. 235/850) featured in al-Isbahani's Book of Songs, and that of "theorists," or exponents of the scholarly tradition rooted in ancient Greek and Islamic sciences, namely the polymath-philosophers al-Kindi (d. c. 256/870) and al-Farabi (d. 339/950).


Medicinal plants represent one of the most important fields of traditional medicine all over the world. In light of the recent emergence of pathogenic bacterial and fungal strains which are resistant to antibiotics posing a challenge for the treatment of infections, the need to discover new antimicrobial substances for use in combating such pathogens become pertinent. Therefore, the aim of the present study is to analyze the composition of phytochemicals and their antimicrobial activity from stem of T. cordifolia by using agar well diffusion method against seven bacterial and three fungal strains. Methanol and aqueous extracts exhibited the high antimicrobial activity while chloroform exhibited moderate activity and hexane showed low antimicrobial activity. Methanol and aqueous extracts showed antimicrobial activity is higher than standard antibiotics against Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Streptococcus pneumoniae, Klebsiella pneumoniae and Proteus vulgaris. Methanol extract was found to be strong MIC against Enterococcus faecalis, Staphylococcus aureus, Streptococcus pneumoniae, Klebsiella pneumoniae, Proteus vulgaris whereas aqueous extract against Staphylococcus aureus and Sterptococcus pneumoniae, at concentration of 31.2 μg/ml. When the concentration of the extracts was increased the zone of inhibition also increased.


Purpose – Satellite and airborne images are increasingly used at different stages of disaster management, especially in the detection of infrastructure damage. Although semi- or full automatic techniques to detect damage have been proposed, they have not been used in emergency situations. Damage maps produced by international organisations are still based on visual interpretation of images, which is time- and labour-consuming. The purpose of this paper is to investigate how an automatic mapping of damage can be helpful for a first and rapid assessment of building damage. Design/methodology/approach – The study area is located in Port-au-Prince (Haiti) stricken by an earthquake in January 2010. To detect building damage, the paper uses optical images (15 cm of spatial resolution) coupled with height data (LiDAR, 1 m of spatial resolution). By undertaking an automatic object-oriented classification, the paper identifies three categories of building damages: intact buildings, collapsed buildings and debris. ...


This paper considers the situation in which the desired three-dimensional impulse response is represented as a finite series, and discusses the spatial domain design of the three-dimensional recursive digital filter, which approximates the desired response by a separable-denominator three-dimensional local state-space model. As the first step, a necessary and sufficient condition is derived for the separable-denominator three-dimensional local state-space model to be separately locally controllable and separately locally observable. It is shown that the condition is equivalent to the minimality of three one-dimensional systems. Then the given three-dimensional impulse response is represented formally in terms of three one-dimensional impulse responses, and the coefficients of the separable-denominator local state-space model are designed through the singular-value decomposition of the Hankel matrices. Finally, the validity of the proposed method is verified by a numerical example.


With the rapid development of Internet technology, people have more abundant ways to obtain information through the
Internet.More and more information is spread in the network, which will produce a large amount of data.The big data type is more
complicated. In order to implement data implementation, the industry is generally combined with different data types and business
scenes, special development and design of different processing subsystems.This method has a large research cost and learning cost,
and a unified computing system platform is relatively lacking, which further makes developers unable to maintain and expand the
system formed by different sets of technology systems.Based on the above situation, this paper designs a universal real-time data
analysis and processing system based on Spark Streaming.


A future B-ISDN (broadband integrated services digital network) will need flexibility for various service requirements and traffic enlargement and fluctuation. The authors define the layer functions for a model of network node functions and for its interlayer interfaces. They also provide a generic example of a node configuration. The necessity of introducing a three-layered transmission system and control and management layers corresponding to each layer for a flexible communications network is presented. The idea of applying self-routing switches to switching equipment in the user layer and cross-connect equipment in the logical layer is also presented.<<ETX>>


Objective To investigate a better method for repair of scalp avulsion with skull exposure.Methods After primary debridement and skin grafting,tissue expanders were placed into subgaleal layer of normal scalp.After enough expansion,expanded scalp flaps were used to repair the skull exposure and the bald deformity.Results All of 6 cases had satisfactory results,wounds were repaired,no bald deformity occurred and no tissue expander infected case was encountered.Conclusion Using this method,we can treat the scalp avulsion with skull exposure without bald deformity.


The Ncf1 gene is a major determinant of disease severity in experimental animal models of Rheumatoid Arthritis. The Ncf1 codes a protein that is important for regulating the activity of the NADPH o ...


This paper reports friction-stir forming (FSF) of cylindrical pin embossments on JIS A5083 aluminum alloy medium gauge plate. A substrate material was put on an emboss die and conducted friction stirring on its back surface. The die has 1mm diameter and 0.5mm deep fine holes at 1.5mm pitch on its top, and the material successfully filled them due to high pressure and heat caused by friction stirring. Three tools having different shoulder diameter were utilized to investigate the deformable area with a single pass. As a consequence, faster spindle speed, slower tool feed rate, and larger tool shoulder contribute to a wider range of completely formed pins. Extrusion of the material to the die cavity seemed to be mostly limited under the area of the shoulder. The ratios of the band width of the complete pins to the shoulder diameter were increased with the larger diameter of the shoulder of the FSF tool. Therefore, a larger shoulder was more effective for wide-range embossing with a single pass. In addition, we evaluated the shape of formed pins with a non-contact 3D measurement system. Accuracy of the height of the completely formed pins was within ±0.013mm, which was comparable with machining.


In this study, three solders, Sn-37Pb, Sn-3.5Ag, and Sn-3.8Ag-0.7Cu were screen printed on both electroless Ni/Au and OSP metal finished micro-via PCBs (Printed Circuit Boards). The interfacial reaction between PCB metal pad finish materials and solder materials, and its effects on the solder bump joint mechanical reliability were investigated. The lead free solders formed a large amount of intermetallic compounds (IMC) than Sn-37Pb on both electroless Ni/Au and OSP (Organic Solderabilty Preservatives) finished PCBs during solder reflows because of the higher Sn content and higher reflow temperature. For OSP finish, scallop-like / and planar Sn intermetallic compounds (IMC) were formed, and fracture occurred 100% within the solder regardless of reflow numbers and solder materials. Bump shear strength of lead free solders showed higher value than that of Sn-37Pb solder, because lead free solders are usually harder than eutectic Sn-37Pb solder. For Ni/Au finish, polygonal shaped IMC and P-rich Ni layer were formed, and a brittle fracture at the Ni-Sn IMC layer or the interface between Ni-Sn intermetallic and P-rich Ni layer was observed after several reflows. Therefore, bump shear strength values of the Ni/Au finish are relatively lower than those of OSP finish. Especially, spalled IMCs at Sn-3.5Ag interface was observed after several reflow times. And, for the Sn-3.8Ag-0.7Cu solder case, the ternary Sn-Ni-Cu IMCs were observed. As a result, it was found that OSP finished PCB was a better choice for solders on PCB in terms of flip chip mechanical reliability.


The reduction in construction and maintenance costs per MW of renewable energy facilities, together with low interest rates, have led to a significant growth in the purchase prices paid for these facilities in the Spanish market. This trend is shared by other European countries, especially for projects that hedge energy price risk incorporating power purchase agreements with third parties. In this framework, questions arise about the economic rationale of the purchase prices paid for these projects. Consequently, we develop a project evaluation model that forecasts expected cash flow and time-varying required rates of return for a standard photovoltaic plant, in order to study the extent to which foreseeable market conditions—interest rates and equity risk premia, among others—translate into economically viable buyouts. Our results suggest that purchase prices paid for these initiatives often lead to buyer returns below those that would be reasonable according to market conditions. Indeed, we find that only facilities that reach a production 23% higher than the number of hours considered in the base case provide returns that compensate long-term financing costs. However, specialised investors can exploit their relatively low cost of financing to pay prices up to 73% higher than those affordable by classic investors.


In this work, we offered a facile strategy to produce lignin microspheres (LMS) with loading of benzotriazole (BTA) inhibitors, which were released as the pH changed. The morphological and composit...


The purpose of this paper is to analyse the issues related to home bias and foreign direct investments (FDIs). We study the role of physical, cultural, and institutional distances from home on FDI decisions taken by corporations to assess whether the globalization of the past two decades has reduced their influence. Using the 'home bias' framework from the finance literature and the gravity model from the economics literature, we utilize a large sample of both developed and emerging markets, using FDI flows of 6263 unique bilateral country pairs over a 30-year period. We find strong empirical evidence of persistent home bias in FDI outflows, and we show that not only physical distance but also cultural and institutional similarities between host and source countries remain a decisive factor in foreign corporate investment decisions. We also show that such home bias is persistent over time and is observed around the world.


Study the fluorescence generated from the target surface of aluminum oxide, titanium dioxide when exposed to high luminescence intensity beam of carbon dioxide laser in atmosphere of oxygen and argon gases each one separately. We found that the intensity of the resulting fluorescence depend on the type and pressure of the gas surrounding the target in addition to the energy density of the laser beam.


Laser welding is a significant method for welding a ll kinds of alloys. High speed welding, low distort i n and easy automation are the advantages of this method. In this study, pulsed Nd :YAG laser butt joint welding was performed on 304 and 316 Austenitic stainless Steels workpieces. All the parameters were designed by Full Factorial Method which the center point wa s repeated for 10 times. Henceforth, the effect of power, pulse duration, la ser velocity and chemical composition on width and depth of welding area, ultimate tensile strength, elongation and Ferrite N umber were studied. The welding process was perform ed in 1.2 and 1.8 KW as power, 3 and 4.4 ms as pulse duration and 0.2 and 0 .8 mm/s as velocity of welding. Thus, the upper lev e of input parameters were selected as the optimal case. This was done by surv eying all the samples to achieve maximum UTS, size of the weld and Ferrite Number. In these conditions, output error for width of weld, depth of weld, U.T.S, elongation and Ferr it Number was 2, 5, 1.6, 25 and 2%.


The results of this study are an evaluation of the mechanics of motion of a weight loaded Manduca sexta Hawkmoth during flight using accelerations recorded with an onboard sensory system. Findings indicate that these 'normal' flapping insects maintain relatively fixed body frequencies in both free and weight loaded flight, which correspond with the driving frequency, or wing beat frequency. Within the analysis, a presence of a harmonic body frequency at twice the wing beat frequency was also discovered. The conclusions from this study indicate an average excess muscle power of over 40mW available in free, unloaded flight. Stability robustness of these flapping insects in flight using the results of a large payload disturbance, 856mg or nearly half to one-third the mass of insect, is demonstrated, and their usefulness as platform for cyborg MAV (CMAV) development is presented.Copyright © 2008 by ASME


There is no doubt that this is a very significant volume for the study of Indonesian Christianity, for the understanding of global Christianity, and for the enhancement of Indonesian studies as a whole. It is significant in the first place because the history of Indonesian Christianity has been largely hidden from the English-speaking world. There are two very clear examples of this. First, in the first edition of the Oxford Dictionary of the Christian Church,1 Indonesia is not mentioned at all; indeed, there is only a brief mention of it in the latest edition.2 3The Oxford Dictionary presents largely an English-language, and, indeed, a British, view of the world. Second, in the classic 1960s history of the Christian worldwide mission, that is, in Stephen Neill's A History of Christian Missionsf we see why Indonesian Christianity may be said to have a "hidden history" from the Westerner's perspective. Most of the primary and even secondary sources of Indonesian Christian history were either in Malay, Indonesian, or local languages of Indonesia. Additional sources were in Dutch and German, and, in earlier years, in Portuguese and Spanish. Neill was conscious of this shortcoming, namely, that many in the English-speaking world were uninfluenced by a whole other, nonEnglish literature, because, after he served as a British Anglican theologian and bishop in Britain and India, he was appointed Professor of Missions and Ecumenical Theology at the University of Hamburg, Germany, in 1962. His classic volume was published two years later, in 1964. When he looked at Indonesia's bibliography, he admitted: "Almost all the literature is in Dutch or German. A history of the Churches in Indonesia has been prepared (in Indonesian) by Dr. T. Muller-Kruger; it is hoped that versions in German and English may be made available before long."4 Neill then goes on to say: "The classic work on the Protestant Church in Indonesia is: C. W. Th. Baron van Boeltzelaer van Dubbeldam, De Protestantsche Kerk im Nederlandsch-Indie: Haar Ontwikkeling van 1620-1939" (The Hague: Martinus Nijhoff, 1947).5 He continues:


This paper is concered with the nonlinear cyber physical system (CPS) with uncertain parameters under false data injection (FDI) attacks. The interval type-2 (IT2) fuzzy model is utilized to approximate the nonlinear system, then the nonlinear system can be represented as a convex combination of linear systems. To detect the FDI attacks, a novel robust fuzzy extended state observer with H∞ preformance is proposed, where the fuzzy rules are utilized to the observer to estimate the FDI attacks. Utilizing the observation of the FDI attacks, a security control scheme is proposed in this paper, in which a compensator is designed to offset the FDI attacks. Simulation examples are given to illustrate the effecitveness of the proposed security scheme.


This study examined the effects of an inquiry-based instructional method on secondary school students' achievement in earth science. Students (N=232) were treated as two experimental groups, one receiving 2 weeks of the inquiry-based instruction while the control group received the traditional lecture-type instruction. Data were analyzed employing an analysis of covariance (ANCOVA) on posttest scores with a pretest as the covariate. The results indicated that students who were taught using the inquiry-based instructional method scored significantly higher than those who were taught with the traditional lecturing approach. In addition, a significant improvement in the achievement test at the comprehensiveand integrated-level test items was accomplished. Contains 31 references. (DDR) ******************************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. ******************************************************************************** ce vi ea 00 The Effects of an Inquiry-Based Instructional Method on Earth Science A Students' Achievement


We present a robust Light Detection and Ranging (LiDAR)-based place descriptor called Scan Context Image (SCI) and a localization method that uses this representation for long-term simultaneous localization and mapping (SLAM). We formulate localization as a conventional supervised classification problem using convolutional neural network (CNN), where a gridded place is considered as a single class and SCIs acquired in that place are the corresponding data to the class. The small (three layers in our work) network is trained with only a single sequence from a single date, which has a total of 579 places and an average 26 data per class. Despite these constraints, we show that a learned network achieves sufficient performance in outdoor (top 5 average accuracy is over 90%) on 13 other test sequences from different dates over 1 year with varying environmental conditions.


A high-speed optical IAN is described, supporting both stream and packet services. A hybrid multiple access protocol. specifically designed for service integration, is presented along with its main charac teristics. Reliability aspects are examined and solved using a network reconfiguration procedure. The transmission subsystem is analyzed, fixing the main characteristics of the network and highlighting the transmission problems.


In view of the difficulties in calculating the shock property of ship-based equipment,the dynamics equation under base shock is founded with base excitation effect coefficient.The way that different accelerating shock is transformed into velocity step is analyzed and the transformation error is also calculated.The big-mass method and relative velocity method are submitted to solve the problem of value inputting for initial velocity in ANSYS.


Objective To investigate the clinical efficacy of rifapentine in treatment of tuberculosis. Methods Patients with tuberculosis in First Hospital of Zibo City from March, 2009 to February, 2013 were randomly divided into control(61 cases) and treatment(61 cases) groups. All patients were po administered with Isoniazid Tablets(0.3 g/d), Pyrazinamide Tablets(1.5 g/d), and Ethambutol Hydrochloride Tablets(0.75 g/d). Patients in the treatment group were po administered with Rifapentine Capsule on the basic treatment, 0.6 g/time, once a week. Patients in the control group were po administered with Rifampicin Capsules(0.45 g/d). All the patients were treated continuously for 6 months. After treatment, the total clinical efficacy was observed, and sputum smear overcast, empty disappear, lesions absorption, and adverse reactions were observe. Results The efficacies in the treatment and control groups were 96.72% and 85.25%, respectively, and there was difference between the two groups(P 0.05). After treatment for 3 and 6 months, the rates of sputum smear overcast, empty disappearing, and lesions absorption were significantly higher than those of control group, and there were differences between the two groups(P 0.05). After treatment for 3 and 6 months, the gastrointestinal tract reaction and number of white blood cells reduced, levels of ALT and AST were significantly lower than those in the control group, and there were differences between the two groups(P 0.05). Conclusion Rifapentine can obviously enhance the clinical curative effect in therapy of tuberculosis with less adverse reaction, which is more suitable for application.


Abstract The application of trivariate thin-plate smoothing splines to the interpolation of daily weather data is investigated. The method was used to develop spatial models of daily minimum and maximum temperature and daily precipitation for all of Canada, at a spatial resolution of 300 arc s of latitude and longitude, for the period 1961–2003. Each daily model was optimized automatically by minimizing the generalized cross validation. The fitted trivariate splines incorporated a spatially varying dependence on ground elevation and were able to adapt automatically to the large variation in station density over Canada. Extensive quality control measures were performed on the source data. Error estimates for the fitted surfaces based on withheld data across southern Canada were comparable to, or smaller than, errors obtained by daily interpolation studies elsewhere with denser data networks. Mean absolute errors in daily maximum and minimum temperature averaged over all years were 1.1° and 1.6°C, respectiv...


There was a high hydrocarbon potential in the evaporite platform dolomite of Middle Cambrian in Tarim Basin.Based on the outcrop observation and the comprehensive analyzes of common thin section, scanning electron microscope(SEM),cathodeluminescence(CL)technique and the geochemical data,we carried out the research on the characteristics of a dolomite reservoir which had deposited in the section of X in Tarim Basin during the Middle Cambrian.The results show that the Middle Cambrian rocks in the study area are of various types,and the reservoir′s space mainly includes the dissolved pores and the collapsed caverns(the collapsed shadowing hole).We also studied the reservoir′s forming mechanism through the assay of accompanying minerals and the analyses of the pore characteristics and geochemical characteristics.It indicates that the mechanisms in the study area include the atmospheric water denudation in syngenetic stage,the collapsing rock′s stacking interaction in middle burial stage and the hydrothermal dissolution in deep burial stage.The former two mechanisms were controlled by the fluctuation of sea level,so they distributed widely.However,the distribution of the third mechanism is quite limited,because it was vertically accompanied by the faults and horizontally distributed along the formation,and it may alter the early generated dissolved pores.


Esterification of oleic acid in supercritical methanol was investigated;the effects of operation parameters such as reaction temperature,reaction time and molar ratio of methanol to oleic acid on the conversion of oleic acid were examined.The results illustrated that the esterification of oleic acid in supercritical methanol can be realized under much milder conditions(i.e.lower temperature,shorter reaction time as well as lower molar ratio of methanol to oleic acid) than the transesterification of grease in supercritical methanol.These suggested that triglycerides first hydrolyze to fatty acids and then the fatty acids undergo methyl esterification to form methyl esters in supercritical methanol.Therefore,it is feasible to use the feedstock containing higher water and free fatty acid,such as waste cooking oil and deodorizer distillate,to produce biodiesel in low cost with supercritical methanol.


The author, in a previous report made an effort to present the concept of "Pressure Efficiency in Respiration" as well as explaining the theory and showing normal values. Contriving this concept, the author began to show the relationship between examination and dyspnea in cardio-pulmonary patients. The purpose was to give a single explanation of dyspnea whether due to obstructive or restrictive impairment based on the concept of "Pressure Efficiency in Respiration". The author has shown that the comparative method of measuring the in-crease of respiratory work commonly observed in both obstructive and restrictive impairment by "Pressure Efficiency in Respiration" will produce a high level of objective validty.


Objective
To explore the changes of surface stress and angle of inclination of femoral head in developmental dislocation of the hip.

Methods
Left hip dislocation model was established surgically in 7 Tibetan pigs while right sides served as control group. Pelvic radiological examination was performed. And bilateral values of Sharp angle and acetabular head index were measured at different timepoints of postoperative immediately, postoperative Month 1 and Month 3 respectively. Computed tomography examinations of pelvis and lower extremities were performed. Then, a three-dimensional finite element model was established for analyzing the characteristics of stress distribution of femoral head and control side.

Results
Postoperative immediately, Sharp angle showed no significant difference between experimental and control sides. At postoperative Month 1 & 3, Sharp angle increased at experimental side versus control side and the difference was insignificant. At postoperative immediately, Month 1 and Month 3, head acetabular index at experimental side decreased versus control side and the difference was significant; ipsilateral comparison showed that, with elapsing time of dislocation, Sharp angle increased at experimental side and the difference was insignificant; acetabular head index decreased with elapsing time of dislocation, the difference was significant. Finite element analysis of surface stress of femoral head: stress distribution of the same site was compared with that of control side femoral head at Month 1 and 3. Stress distribution significantly increased at experimental side and the difference was statistically significant (P<0.05); With elapsing time, stress value of medial femoral head at experimental side and lateral stress of femoral head increased and stress distribution of the same site was statistically significant (P<0.05).

Conclusions
Increase of anterior tilt angle and deformation of femoral head and acetabulum occur gradually and it is correlated with surface stress distribution of femoral head. Thus early detection, timely operation and correcting anterior tilt angle are essential.

Key words:
Hip dislocation, developmental; Finite element analysis; Models, animal


The polymorphism of TGFB3 gene in Qianbeima goat,Inner Mongolia cashmere goat and Guanzhong dairy goat was detected by PCR direct sequence method based on a pair of specific primers selected from TGFB3 genomic sequence(NM_001101183) in cow to provide the theoretical basis for goat breeding.The results showed that there was a polymorphism locus(SNP G-212-A) at 212 bp of the first exon of TGFB3 gene in Qianbeima goat,there were 28 transcription factor binding sites with more than 96 scores(two CdxAs,eighteen HSFs,two ADR1,one AML1a,three GCR11s,one cap and one SRY) by analyzing regulator sequence of TGFB3 5'flank but CpG island was not detected in TGFB3 5'regulator region.


Sparse Random Linear Network Coding (RLNC) reduces the computational complexity of the RLNC decoding through a low density of the non-zero coding coefficients, which can be achieved through sending uncoded (systematic) packets. However, conventional recoding of sparse RLNC coded packets at an intermediate node in a multi-hop network increases the density of non-zero coding coefficients. We develop and evaluate sparsity-preserving recoding (SpaRec) strategies that preserve the low density of non-zero coding coefficients of sparse RLNC with systematic packets. We develop SpaRec strategies with and without decoding at the intermediate nodes, with and without a specified coding rate, as well as with finite and infinite recoding window lengths. We evaluate the SpaRec strategies in multi-hop networks in terms of packet loss, packet delivery delay, as well as recoding and decoding (computation) throughput. We find that the SpaRec strategies substantially improve the RLNC performance compared to conventional recoding.


A Bifidobacterium surface expression gene for expressing an immunogenic polypeptide on the surface layer of the bifidobacteria, the gene includes a gene encoding the immunogenic polypeptides, the immunogenic polypeptide is predetermined It includes a base domain and at least one antigenic peptide, the at least one antigenic peptide is coupled to either the N-terminal side and the C-terminal side of the base panel domain. Bifidobacterium surface expressed genes of the present invention may further comprise a gene encoding a GNB / LNB substrate binding membrane protein from Bifidobacterium.


This report is submitted in fulfillment of the lesson plan assessment request made by the Department of Environmental Studies, Nagasaki University. Lesson plan assessment is based on the lesson units designed by the author for Language Communication AI/AII courses in the Department of Environmental Studies. Instructional approach utilizing a Cyber Classroom created by online resources at TaskStream® is introduced by the author. A Cyber Classroom offers supplementary instruction that promotes self-study and maximizes classroom instruction while supporting student and task-based learning.


Metrology Corporation Malaysia Sdn Bhd was incorporated with the sole objective of providing the verification and re-verification services for all weighing and all measuring instruments use for trade in Malaysia. The company started operation on the 4th April, 2005. Before that all the weighing and measuring instruments were verified and re-verified by the Metric Unit, Enforcement Division, Ministry of Domestic Trade And Consumer Affair. This project paper will focus on how this firm performance during 4 years ago. Start from 2007 until 2010. This project paper will calculate the ratio analysis of this firm that been extract from income statement and balance sheet. To concrete this ratio, the researcher also includes a common size analysis as the side evidence about this company financial performance. The purpose of this analysis, to compare how the company performance throughout from 2007 until 2010. Data are being collected by interview, journal. Thus further studied being done to show how the financial position about this firm.The result indicates that, the used of these method contribute to the reasons and evidence that based on the trend of the financial statements.


To give rigorous mathematical proofs of chaotic behaviors in a given system, it is necessary to identify the homoclinic structures in the system. In this tutorial review, methods for constructing explicit solutions for nonlinear partial differential equations are presented, with more emphasis placed on those utilizing complete integrability associated with soliton equations. As an extended application, homoclinic orbits to spatial uniform plane waves of coupled modified nonlinear Schrodinger equations are obtained via the dressing method. During the procedure, it is necessary to introduce the Lax pair for these coupled equations, as well as its Floquet spectral analysis and corresponding Bloch functions.


It has been argued that the end of the Cold War signaled the waning influence of Non-Align Movement (NAM). NAM had been considered a third force during the Cold War rivalry between two superpowers but after the war the movement appeared to lose its momentum and failed to achieve the aspirations of the Bandung Spirit conference of 1955, which called for political cooperation among newly independent Asian and African countries. This article discusses to what extent the Bandung spirit continues to inspire the NAM's struggle for self-respect and self-determination among developing countries post-Cold War and analyses the major challenges NAM faces in reviving its status as a respected international organization representing developing countries in the current unipolar international political system. Finally, the article explores Malaysia's part in reinvigorating the Bandung spirit among NAM member countries since the 1997 Kuala Lumpur Summit.


In this study we mapped the Rosaceae species richness with the point-to-grid richness analysis tool DIVA-GIS, using a 10×10 kilometer grid cell and the circular neighborhood option with the 50 km radius, to identify potential areas for conservation of Rosaceae. This analysis is accomplished by 5762 georeferenced observations. The main potential areas for conservation of this family in Iran belong to the Irano-Turanian Region with its two important parts including central Alborz and Zagros Mountains respectively. These areas cover the centre of endemism of the family in Iran. The Rosaceae has 91 rare and 70 endemic species. Mazandaran with the highest number of rare species (23) is one of the most important areas for conservation (in central Alborz).


Herbal dietary supplement sales saw their strongest sales growth in more than 15 years in 2017, according to new figures out from the HerbalGram Herb Market Report published by the American Botanical Council.


Rain radar for the TRMM follow on mission should be a conservative one because of the short time for development. The basic requirement for the radar may be to keep the data quality, such as sampling number, spatial resolution, etc. the same as the TRMM rain radar. Since the TRMM follow on mission should measure the rainfall over not only the tropical region but also the mid-latitude region, the swath must be widened to keep the sampling number. The altitude of the satellite is expected to 400-500 km, which helps to widen the radar swath. The basic configuration of the radar should be the same as one for TRMM to use the TRMM heritage fully.<<ETX>>


In this paper,we continue our discussion of the application of the nonlinear prediction model which was given in our previous work.The prediction ofnoisy chaotic time series using this model and its relationship with the embedding dimensions are studied through nomerical experiences.


Message Ferrying is a new approach developed to assist communication in Mobile adhoc networks. Mobile ad-hoc networks are typically deployed with limited infrastructure. In addition, due to various conditions like limited radio range, physical obstacles or inclement weather, some nodes in the network might not be able to communicate with others. This could result in a disconnected network. In such situations, a typical network protocol might not yield good results. Message Ferrying is an approach which works around such problems. The message ferrying technique makes use of mobile nodes, called "ferries", which are able to collect and transport data from one node to another. There are two approaches to deliver a message, Node-Initiated Message Ferrying (NIMF) and Ferry-Initiated Message Ferrying (FIMF). In NIMF approach a node will move towards known route of ferry if it has data to transmit or receive. The node comes close so that ferry will be in normal range of node. In FIME approach the ferry broadcast its location periodically. When a node wants to send or receive messages via the ferry, it sends a service request message to the ferry using its long range radio. This message contains the information of node location. According to this information ferry will adjust their trajectory to meet the node. After finishing the data transfer ferry will return to its default route. This paper propose an improved version of NIMF, called Improved NIMF where the source/receiver nodes makes no movement towards the ferry, instead they select other nodes in their connected network which are nearer to the ferry with enough buffer space to send or receive their data to/from that node. Then that particular node transmits/receives the data to/from the ferry and receive/pass from/to actual sender/receiver. Through simulation experiments it is proved that the proposed approach works better than the NIMF.


Independent vector analysis (IVA) utilizing Gaussian mixture model (GMM) as source priors has been demonstrated as an effective algorithm for joint blind source separation (JBSS). However, an extra pre-training process is required to provide initial parameter values for successful speech separation. In this paper, we introduce a time-varying parameter in the GMM to adapt to the temporal power fluctuation embedded in the nonstationary speech signal so as to avoid the pre-training process. The expectation-maximization (EM) process updating both the demixing matrix and the signal model is altered correspondingly. Experimental results confirm the efficacy of the proposed method under random initialization and further show its advantage in terms of a competitive separation accuracy and a faster convergence speed.


Background:The pandemic of coronavirus disease (COVID-19) has affected every aspect of our life. Fear of the corona virus may trigger safety measures. However, when fear is exaggerated, it may result in maladaptive behaviors. Physicians are among the high-risk groups of infection. They may have more psychological burden and behavioral changes. Aim:To assess the fear of COVID-19 among Egyptian physicians. Subjects and Methods: A cross-sectional online survey was developed. A free software google form was used to send the questionnaire and the informed consent. A convenient sample was used to recruit participants. A total of 382 Egyptian clinical physicians completed the questionnaire. The questionnaire included demographic variables and the fear of COVID-19 Scale. Results: Female physicians were found to have significantly higher fear score compared to males (p=0.012). Moreover, physicians who had observed higher number of COVID-19 patients per week had significantly higher fear score (p < 0.001). In our sample, there was negative correlation between age and Fear of COVID-19 scores among the studied physicians. Conclusion: The pandemic of COVID-19 is associated with significant fear among Egyptian physicians, especially females. Specific interventions are needed to prevent irrational fear during COVID-19 pandemic among Egyptian physicians.


Advance in genetic diversity of Chinese local yellow cattle blood isozyme and its application in bovine genetics were reviewed in this contribution.


To properly detect the face region and improve the accuracy and real-time of face detection and location method in the circumstance of inadequate light of vehicle cab,face detecting method based on skin color clustering is used to segment the color image into skin and non-skin areas.Meanwhile,a new algorithm based on Retinex algorithm is proposed to illumination compensation before the face detection.Simulation experiment has been done with the improved algorithm applied to the newly created database of face image.The detection correctness rate is increased by 4.7 % when the algorithm is compared with the traditional method.The experimental result prove that this algorithm has good adaptability to the images containing face rotations with different illumination intensity,and it has excellent practical value.


Halal certification is very prominent to the restaurant industry in Malaysia but the actual implementation of its Standards is crucial for the comprehension of those who are unfamiliar with Islamic dietary rules. The purpose of this study is to determine the expectations of Muslim and non Muslim restaurant entrepreneurs toward halal certification in Malaysia as the demand for halal food is growing at fast pace. A nationwide mail survey has been conducted involving 13 states and Federal Territory of Kuala Lumpur that covered halal certified, halal claimant and non halal restaurant.
Three techniques that include factor and Cluster analysis as well as independent T-test were conducted to show a clear difference between the Muslim and non Muslim restaurant entrepreneurs. Factor analysis has listed that there were seven dimensions of halal certification whereas the Cluster analysis showed that the respondents were separated into three distinct groups that include 'Certiflcation Advocates', 'Certiflcation Ambivalents' and 'Compliance Cost Focused'. It is gathered that there were significant differences between Muslim and non-Muslim respondents on factors like market signals, Islamic attributes, marketing benefits, cost of compliance and local awareness. However, cost of certification and non-Islamic attributes showed that the differences were not significant. This study is the first to investigate the expectations of restaurateurs with
different religious background toward halal certification with the implication for restaurant Operators and hospitality industry practitioners to recognize the importance of halal certification for both Muslim and non Muslim restaurant patrons.


Review of: MUNOZ, Maria L.O. Stand Up and Fight : Participatory Indigenismo, Populism, and Mobilization in Mexico, 1970-1984. Tucson: University of Arizona Press, 2016.


In lattice Schrodinger picture, the wave functionals of the squeezed vacuum states of a free real scalar field in de Sitter space are constructed explicitly in momentum space by using the method of instantaneous Hamiltonian diagonalization. The modified power spectrum and particle production in the general mixed, squeezed initial states are also presented. For the massless minimally coupled scalar field which is relevant to slow roll inflationary models, we recover the power spectrum of scalar fluctuations for the squeezed vacuum states, and show that the evolution of the squeezed vacuum states exhibits an attractor behavior. The case of a massless conformally coupled scalar field is also discussed.


A study has been made of the combustion of different waste oils produced in an iron and steel works. Combustion is achieved by injecting the waste oil at flows of 10-20 kg/h in a combustion chamber that simulates the conditions of the blast furnace tuyere zone. The waste oil is preheated to 65-90 °C in order to achieve conditions of fluidity and is injected by spraying into the combustion chamber. During combustion the temperatures and the CO 2 , O 2 , CO N 2 and H 2 contents of the gases in the combustion chamber are constantly recorded. The efficiency of the combustion of each waste oil is determined.


Unevenness is a feature of sustainable development of Russian territories. It arises due to the impressive difference in the provision of natural resources, residents' mentality, natural and climate factors, the infrastructure that has formed over the years of territory's existence, and other various conditions. The purpose of the issue is the research of the main factors reflecting the sustainability of development of Russia and proposes directions for improving the social, economic and environmental policy of the country.


Objective
To investigate the clinical significance and interrelation of long-chain non-coding RNA (lcnRNA) HOXA transcript at the distal tip (HOTTIP) and metabotropic glutamate receptor 1 (mGluR1) in pancreatic cancer patients.

Methods
Pancreatic cancer samples, which were treated in our hospital were collected. The expression levels of HOTTIP and mGlUR1 mRNA were detected by reverse transcriptase-polymerase chain reaction (RT-PCR) in fresh pancreatic cancer tissue, and those of HOTTIP and mGluR1 protein by Western blotting and immunohistochemistry. Moreover, the relationship between the expression of HOTTIP, mGlUR1 and clinicopathological features was analyzed.

Results
The levels of HOTTIP and mGlUR1 mRNA and protein were significantly up-regulated in pancreatic cancer tissues as compared with normal pancreatic tissue (P=0.000). The expression of HOTTIP protein was positive in 32 samples (68.09%) and mGlUR1 protein was positive in 30 samples (63.83%). The positive rate of HOTTIP and mGlUR1 in adjacent tissues was 31.91% and 36.17%, respectively, and the difference was also statistically significant (P=0.000). The expression of HOTTIP and mGluR1 was correlated with lymph node metastasis, differentiation degree and TNM stage (P=0.000, 0.004, 0.000). The survival time of HOTTIP and mGlUR1 positive patients was significantly shorter than that of negative patients (P=0.029, 0.047). Cox regression multivariate analysis showed that lymph node metastasis, differentiation degree, TNM stage, HOTTIP and mGlUR1 expression were independent prognostic factors for pancreatic cancer (P=0.022, 0.048, 0.026, 0.000, 0.002). In addition, HOTTIP and mGlUR1 expression showed a significant positive correlation in cervical cancer patients (r=0.689, P=0.002).

Conclusion
The positive expression of HOTTIP and mGlUR1 is associated with the occurrence, progression and prognosis of pancreatic cancer.

Key words:
Pancreatic cancer; HOXA transcript at the distal tip; Metabotropic glutamate receptor 1; Pathological features; Prognosis


Delamination is one of the most commonly observed failure modes in laminated composites. The existence of delamination in a structure can significantly reduce the stiffness and strength of the structure. The simulations of delamination are performed by two different methods: Virtual Crack closure Technique (VCCT) and Cohesive Zone Method (CZM).VCCT is a fracture mechanics approach which is widely used to compute energy release rates. CZM is a progressive event governed by progressive stiffness reduction of the interface between two separating faces which uses bilinear material behavior for interface delamination and fracture energies based debonding to analyze delamination of unidirectional Double Cantilever Beam (DCB) specimen. The proposed methods are validated with the benchmark results. The load-displacement response predicted by CZM agreed well with the benchmark results. The other approach, VCCT, also successfully simulated the load-displacement response curve but this method overestimated the critical load. Parametric study is carried out for a range of height of the beam and load-displacement response is studied.


Abstract This paper evaluates the factors responsible for maintaining substantial military expenditures in Greece and Turkey. The presented research encompasses theoretical and empirical aspects. First, defense spending by both countries was analyzed based on statistical data from international sources. Next, the theoretical determinants of budgetary spending are reviewed, which consider political, economic and military factors behind high expenditures on the army in Greece and in Turkey. Finally, Granger causality tests is applied to determine whether a causal relation between variables exists in the case of these two countries. We conclude that defense expenditures in Greece and Turkey exceed the NATO average, but are relatively low relative to those of selected Middle Eastern countries. Our results indicate that high military spending level in Turkey is mainly driven by national security concerns, whereas an economic driver prevails in Greece.


This study proposes a Naive Bayes (NB) classifier model for predicting congestion and incident in urban road networks. NB is a machine learning classification model based on Bayes' theorem with strong (probabilistic) independence assumptions between predictor variables. This study considers congestion or incident as a target variable and applies a NB model to classify its state (i.e., occur vs. not occur). Predictor variables or features considered in this study include network environment variables (time of day, day of week, and weather) and traffic condition variables (speed on bottlenecks). This study develops a data-driven approach for building and validating NB models. The models are trained and tested using actual traffic, incident, and weather data collected from Brisbane, Australia in 2014. The validation results show that the proposed models can successfully predict congestion and incident occurrence with a desired level of accuracy.


The electrochemical oxidation of zirconium and hafnium double-deckers M(P)2 (M=Zr, Hf; P=OEP, TPP) (Scheme 1)2) leads to mono- and dications which show near infrared absorption bands which are of ≈ 2000 cm-1 higher energy than those of the corresponding cerium double-decker cations. [Zr(OEP)2]X, [Zr(OEP)2]X2, and [Zr(TPP)2]X (X=ClO4− and PF6−) are isolated after electrochemical oxidation and are characterized by IR and NMR spectroscopy. Magnetic susceptibility measurements (2 K < T < 300 K) of the solids confirm the strong coupling of the electron spins in the diamagnetic dication salt [Zr(OEP)2][ClO4]2. The molecular structure of Zr(OEP)2 is elucidated by an X-ray structural analysis.


This article builds the confidence for undergraduate electrical/electronic engineering students in low-power very-large-scale integration by presenting a simple technique for enhancing the performance of precomputation-based content addressable memory. The proposed precomputation method provides minimal power consumption and has enhanced speed than the existing design. Experimental results were obtained using the cadence virtuoso 90 nm. The paper provides hands-on teaching in the basics of content addressable memory and low-power very-large-scale integration technique, stimulates students' interest in very-large-scale integration, and scrutinizes pros and cons of different circuit choices.


The methods for remaining useful life (RUL) prediction of bearings are mainly based on the autoregressive strategies, among which the temporal convolutional network (TCN) has been recently developed and is widely believed as the high-performance one. These methods generally suffer from errors of prediction. In this article, we newly design the Bayesian-optimization-based adversarial TCN (AdTCN-BO), by embedding the TCN into the adversarial training framework as the generator. Within the framework, the discriminator is designed to continuously correct the output value of the generator in the training process, thus reducing the errors of prediction to a certain extent. Based on the AdTCN-BO, a novel RUL prediction approach for bearings is developed. An experimental verification is carried out to validate the effectiveness of the proposed approach, demonstrating that the AdTCN-BO framework is more accurate in contrast to the traditional data-driven methods of RUL prediction.


Abstract This article arises from surveys between 1987 and 1989 among representative samples of 16–20 year olds in Swindon and Liverpool. The young people in the former town ran the lower risk of unemployment, had the higher paying jobs and higher personal incomes on average, and, therefore, the higher levels of leisure spending. Overall, however, the young people in Liverpool had the higher rates of participation in leisure activities. Within each area the young people with jobs had higher rates of leisure participation than the unemployed but this intra-area difference was not mirrored neatly at the inter-area level. The authors discuss how young people in a high unemployment city such as Liverpool were able to maintain relatively high overall levels of leisure activity by drawing upon family resources, forgoing particularly expensive activities and purchases, and scaling down their spending on other leisure goods and occasions. The authors also discuss the ways in which the resilience of leisure among ...


AIDS is an acquired immunodeficiency syndrome. Since 1981 when the first case of AIDS was found,during the first 20 years, the number of worldwide HIV infection maintained a significant increasing trend. In the recent10 years, the growing trend has become mild because of effective preventive measures and improved treatment strategies for AIDS. Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis. It can involve multiple body organs. After infection, it does not have to attack immediately, only does when the patient is weak, such as in AIDS patients. Since HIV was found in human, AIDS often goes with tuberculosis especially in areas with underdeveloped economy and poor medical conditions where scientifical and complete treatments are hardly accessible. The two diseases affect each other. During the last decade, economic and life conditions get improved a lot and people enjoy a good physical condition generally, as a result, both of the two epidemic diseases slow down in infection and incidence rates. The epidemic situation of the two diseases have a significant correlation.


This paper presents a novel blind multiple access interference (MAI) suppression filter in DS/CDMA systems. The filter is adaptively updated by parallelly projecting them onto a series of convex sets. These sets are defined based on the received signal as well as a priori knowledge about the desired user's signature. In order to achieve fast convergence and good performance at steady state, the adaptive projected subgradient method (Yamada et al., 2003) is applied. The proposed scheme also jointly estimates the desired signal amplitude and the filter coefficients based on a stochastic approximation of an EM type algorithm, following the original idea proposed by Park and Doherty, 1997. Simulation results highlight the fast convergence behavior and good performance at steady state of the proposed scheme.


Computing similarity between XML documents has been a big puzzle in documents classifying. This paper firstly proposes a model for computing XML documents similarity. Then it uses XMLGenerator to simulate implementing test. The paper describes a method based on structure, which uses sequential pattern mining approach to find out the maximal common paths in two XML document trees. Then we measure similarity as the ratio between maximal common paths and all paths extracted from XML document tree. A novel approach to minimize XML document is proposed and semantic similarity and structural similarity are both considered to improve similarity between two XML documents. There is a good future of our method.


We study crustal deformation in the Krafla and Theistareykir volcanic systems in the Northern Volcanic Zone of Iceland. Krafla experienced a major rifting episode in 1975-1984, and is also the site of a 60 MW geothermal power station. About 20 km to the north-west of Krafla, Theistareykir is mainly known for its geothermal activity, and plans exist to use the area for geothermal energy extraction. Previous studies have shown several deformation signals in the area, including continuous subsidence of the Krafla caldera, intrusive activity in the Theistareykir central volcano and a broad uplift signal to the north of Krafla. Poor spatial and/or temporal resolution in measurements used during previous studies have made it difficult to correctly identify and separate different signals. Here we present results from a combined study of InSAR and GPS data, which yields deformation maps over wide areas around Krafla and Theistareykir with unprecedented resolution. This allows us to not only obtain new constraints on previously identified displacements, but also reveals a subsidence source at Bjarnarflag geothermal field, in the southern part of Krafla's central volcano.


Abstr Biodiesel has become more attractive recently because of its environmental benefits and the fact that it is made from renewable resources. The most common way to produce biodiesel is through transesterification. In spite of the many advantages of biodiesel, it is not yet commercialized all over the world. The major problem is the cost of the raw material. Waste cooking oil is a promising alternative to vegetable oil due to its reduced cost. Biodiesel was prepared via the transesterification of the esterified mixed oil, waste home domestic oil and restaurant waste cooking oil with excess alcohol using potassium hydroxide as an alkaline catalyst. The effects of reaction temperature, time and alcohol to oil ratio, catalyst type and concentration on the conversion of diesel were examined. Comparison between the analytical methods used to measure the conversion of biodiesel was evaluated and the maximum conversion of approximately 98.6 using TGA analysis and 97.6% using GC were obtained. The biodiesel conversion s as measured by TGA and GC are found to be approximately the same as the linear fit between the two data series results for R 2 value of 0.9983.


Adverse childhood experiences (ACE) have a great impact on mental health outcomes of adults. However, little is known whether ACE may act as modulators of the mental health of health professionals caring for patients with COVID‐19.


(75) Inventor: Anupam Sanyal, Naperville, IL (US) 0 Buecker et al., Power Engineering, Fuel Switching, PRB (73) Assignee: Benetech, Inc., Montgomery, IL (US) Coal Switch Not A Complete Panacae, pp. 76, 78 and unnumbered page, Nov. 2000. (*) Notice: Subject to any disclaimer, the term of this Hottell et al., Radiant-Heat Transfer, Section 4.3, pp. patent is extended or adjusted under 35 66-67, publication unknown, date unknown. U.S.C. 154(b) by 44 days. * cited by examiner (21) Appl. No.: 09/758,666 (22) Filed Jan. 11, 2001 Primary Examiner-Cephia D. Toomer CC an. 1, (74) Attorney, Agent, or Firm Thompson Coburn, LLP


Children are undoubtedly a blessing, albeit an expensive one, and adopted children are no exception. It is not uncommon for families to spend upwards of $15,000 in application, agency, and attorney's fees during an adoption. In the end though, adopting a child can be every bit as rewarding to a family as giving birth to a biological child. In 2007, Justin and Eleece Sanders applied to adopt a baby girl. They were thrilled when, eight weeks after applying, it looked like they would be bringing their new daughter home. Unfortunately, the birth father decided he could not give up his baby, and the adoption fell through. The whole family was heartbroken. Thankfully, the Sanders' story ends happily. In 2008, their dreams came true when they found another birth mother who wanted to give her child up, and they brought their beautiful daughter home at last. Sadly, unlike the


On May 25, 2020, Derek Chauvin, a Minneapolis police officer, murdered George Perry Floyd Jr., and protests erupted in cities and towns across the country. The public health threat of anti-Black police violence in the wake of the pandemic and, more directly, Floyd's murder led many to describe "twin pandemics" of COVID-19 and racism, a framing that circulated widely. As the analysis emerging from the Black Lives Matter movement has made clear, these are not separate threats: the disproportionately high morbidity and mortality rates in communities of color clearly manifest the structural racism that is, in turn, foundational for public health disasters. It is not surprising that women-of-color feminism has laid the groundwork for an analysis emerging from a movement inaugurated by three Black women. Our essay builds on that work to explore an emerging vocabulary these insights have generated: the adoption of phrases such as "systemic racism" and "white supremacy" as the lingua franca of mainstream media, which has gone largely unremarked, as well as the Merriam-Webster Dictionary's redefinition of "racism." We argue for the importance of a changing vocabulary that at once registers and facilitates efforts to address structural racism and the violence it perpetuates.


© The Author(s), 2022. Published by Cambridge University Press on behalf of The Association for Clinical and Translational Science. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/ by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. Cross walk between consensus recommendations and new NCATS PAR-21-293 requirements for D&I in CTSA hubs


The application of computer to rubber instrument technology and the effect of computer instrument system on the traditional instrument system were introduced briefly. The new automatic determination system had fast speed, high precision and more composition functions, which would meet more requirements of consumer.


Developing a dynamic simulation system of unconventional emergency evolution analysis is of great significance for unconventional emergency management.To cover the shortage of existing simulation methods and systems which are used in unconventional emergency evolution analysis,especially their deficiency in integrating the theories,methods and technology achievements within multi-disciplinary and multi-field,a framework of unconventional emergency simulation system is proposed based on knowledge unit,and with the fusional computation of data,knowledge and model as the core of the framework.Then the implementation of every subsystem is discussed.In this system,the internal relationships among data,knowledge and model are achieved by the knowledge unit.And through the reasoning of the knowledge unit network,the fusional computation of data,knowledge and model within various disciplines and fields are realized.Then the simulation of unconventional emergency evolution analysis is further achieved.Finally,a prototype of the system is put forward.And the process of management and running of the prototype are illustrated through an example of debris flow disaster.


A study was conducted to evaluate in vitro efficacy of seaweed (Sargassum myriocystum and Sargassum wightii) and seagrass (Cymodocea serrulata and Syringodium isoetifolium) extract against the mycelial growth of Macrophomina phaseolina at different concentrations of 5, 10, 15 and 20% along with control by poison food technique. The result revealed that, the extract of S. wightii (20%) exhibited the highest suppression of mycelial growth (10, 25 and 38 mm) at 24, 48 and 72 h after incubation. Among the antagonists tested against Macrophomina phaseolina, the fungal Trichoderma viride was found to be the most effective in reducing mycelial growth than the bacterial antagonist Pseudomonas fluorescens. Both the antagonistic fungi and bacteria have compatibility with seaweed and seagrass extracts in the concentrations.