Immunotherapeutic approaches such as CAR-T and T cell engaging bispecific antibodies have shown positive clinical outcomes and demonstrate the value of harnessing cytotoxic T lymphocyte (CTL) activity for tumor intervention. Here we describe Engineered Toxin Bodies (ETBs) with Antigen Seeding Technology (AST) as a unique tumor targeted therapeutic approach to recruit endogenous polyfunctional memory CTL responses against cancers.
 Molecular Templates' ETB platform combines antibody domains with a proprietary form of the Shiga like Toxin A (SLTA) subunit to specifically target cells and exploit SLTA's intrinsic ability to self-internalize and destroy ribosomes. With the addition of a foreign class I antigenic peptide fused to an ETB (AST), antigens present in complex with endogenous MHC I to initiate a high avidity T cell response to target cells. Utilizing this approach, we demonstrate ETBs targeted to clinically relevant markers can seed antigenic peptides to hematological tumor, solid tumor, and primary cells.
 Expanded CTLs from donors with preexisting Human Cytomegalovirus (CMV) reactivity phenotypically resembled memory expansion from natural infection. We next delivered class I CMV peptide to tumor cells by AST with ETBs targeted to PD-L1 and co-cultured tumor cells with expanded CTLs. This led to activation of CMV specific T cells, direct tumor-T cell engagement, and potent cell kill activity above that of parental ETBs. CTL phenotyping and cytokine profiling revealed polyfunctional T cell activation driven by AST enabled ETBs. Thus, ETBs delivering peptide via AST provide additive mechanisms of action: direct cell kill via ribosomal destruction, and antigen specific polyfunctional memory CTL activation.


The author shows that the Russian Orthodox Church throughout the centuries has combatted superstition on theo logical grounds. Nonetheless, many Orthodox parishoners, and to some extent the clergy themselves, manifest elements of superstition. In the popular mind, and to most Soviet scholars, Baptism takes a more consistently conscious and rational approach to religious faith. Baptism, too, is firmly against superstition, but many Baptists are superstitious. Even non-believing members of the Soviet intelligentsia are not immune. The author analyzes the nature of superstition both in theory and in fact (on the basis of field work).


The importance of rapid identification of the victims in mass disasters is essential for legal and humanitarian reasons. When the individual is edentulous, where almost all valuable identification components of oral cavity are lost, the positive identification can be achieved through marked dentures. This paper emphasizes the importance of denture marking and reviews the different denture marking methods.


Due to the degradation of an aerial image due to occluding of sunlight, namely shadows, algorithms like segmentation and object recognition may be highly influenced negatively. This paper describes a novel shadow restoration algorithm based on atmospheric effects and characteristics of sun-light for aerial images. In this work, first shadow regions are detected exploiting the Rayleigh scattering phenomena and the fact that shadows have low illumination intensity. After detection shadow restoration is achieved by first restoring partially occluded shadow areas, with modeling these transition regions with a sigmoid function. Then, fully occluded shadow regions are restored by first segmenting the image to uniformly illuminated regions, then multiplying the intensity in these regions with a constant, which is determined by the ratio of intensities between each segment and its non-shadow neighborhood. The experimental results yield better results when compared with the other methods in the literature.


We classify the "fully tight" simply laced Coxeter groups, that is, the ones whoseiji-avoiding Kazhdan–Lusztig basis elements are monomials in the generatorsBsi. We then investigate the basis of the Temperley–Lieb algebra arising from the Kazhdan–Lusztig basis of the associated Hecke algebra, and prove that the basis coincides with the usual (monomial) basis.


ABSTRACT In this paper we interrogate how different research assemblages act as affect-enhancing devices for elections by drawing from the 2015 Canadian Federal election. The paper uses scholarship from media events traditions to devise an ontological framework for analysing the mediatization of elections and to show how research assemblages propagate a myth of the mediated centre. We then discuss two examples of how research assemblages are deployed as mood enhancing devices within election coverage. The first example focuses on how polling data is deployed to generate and sustain a myth of the mediated centre within an ontology of expectation. For the second example, we turn to how the emergence of a participatory condition in contemporary sociality introduces an ontology of anticipation that further problematizes the role of research assemblages in the mediatization of elections. In the final sections of the paper, we examine a case study of Creative Publics: Art-Making Inspired by the Federal Election to discuss alternative approaches to researching elections that also draw on an ontology of anticipation. We show how alternative research assemblages can channel the anticipation generated by participatory politics to yield more diverse and critical forms of participation in the lead up to elections.


When there is a order of a temporary injunction, it"s ordinary that is registered. It"ll be a problem whether the effect of the order forms when doing the order, or when registering the order. It was settled by legislation in Japan about this problem. However, it isn"t clear whether this problem was settled in legislative way in our country. It"s in the current state studied by a practitioner mainly about this problem. A precedent of an important Supreme Court case about this problem has gone out recently. This study treats this problem with the precedent as a material. This precedent quoted and judged the effect of the injunction to suspension of the exercise of duties with quoting the Commercial Law. Supreme Court An Areopagus judged that its effect formed when doing the order as a principle. When court does a temporary injunction actually, the registration also combines, so there are almost no cases that it"ll be a problem as of the occurrence of the effect of the order. However, registration is sometimes impossible, so it is understood its effect to form when doing the order. When revising the Civil Enforcement law from now on, we"ll need enough consideration about this problem.


This study examined the causal relationships between eight factors determining the perceived importance of school board functions and effective schools. Measures were obtained from 84 school districts in a mid-western state. Two instruments were used, a self report survey for school board members, and a school effectiveness rating determined by regional educational specialists. The school board data were factor analyzed, and eight constructs emerged. A regression model adjusting school effectiveness ratings for two demographic characteristics was used to obtain the dependent variable for the path model. Path analysis findings did not verify that there was a causal relationship between perceived school board functions and effective school districts. In recent years attention in education has been focused on how to improve our methods of instruction. New technology and progressive methods have been implemented by administrative and instructional leaders. Educators have been encouraged to experiment with a variety of teaching and learning styles in an effort to facilitate the acquisition of skills and thought processes. Along with the surge in awareness of improving instruction, equally there has been a push for accountability. Traditional methods of measuring student performance have provided incongruous results to which schools are "doing the job" and why. Because many studies are conducted at the elementary level, it is often


The existing safety guarantee systems for the railway operation in China only focus on upgrading their information technology, while their auto-control and intelligent capacity are relatively low and the auxiliary decision making capacity is poor. Knowledge Discovery in Data Bases (KDD) enables us to find out potentially useful information from mass database so that the decision will be more accurate. Appling knowledge discovery to decision making of railway operation safety can improve the intelligent, real-time and integration performance of the system. This paper applies case-based reasoning to accident treatment, and shows important significance to assist the decision making for train running safety.


BACKGROUND
The long-term success of implant therapy depends not only on proper osseointegration, but also on the healing of the epithelium and the quality of the biological seal on the abutment and on the implant neck. This study aims to evaluate the possible use of dentinal adhesives on the surface of the transmucosal path of dental implants in order to create a hermetic seal between keratinized epithelium and abutment.

METHODS
Four sections of 12 µm thickness were obtained from a sample of the oral mucosa. Scotchbond TM Universal Adhesive (3M ESPE, Seefeld, Germany) was carefully applied both to the samples and to the transmucosal path of titanium abutment (Win-Six, BioSAFin, Italy). The adhesives were polymerized. FT-IR analysis was performed on: 1) polymerized Scotchbond Universal Adhesive (3M ESPE, Seefeld, Germany); 2) the interface between the titanium abutment and the adhesive; 3) the interface between the adhesive and the mucosa; 4) the mucosa samples.

RESULTS
Comparing the spectra, it emerged that the adhesive has established chemical bonds both on titanium and on the keratinized mucosa, involving different types of chemical interactions.

CONCLUSIONS
The results of this in-vitro study are encouraging. In the future biocompatibility and comparative study with other adhesives will be required.


Experiments and numerical simulations show that the energy spectrum of the magnetohydrodynamic turbulence in the quasi-static limit deviates from Kolmogorov's k −5/3 spectrum as the external magnetic field, or equivalently the interaction parameter, is increased. To explain this phenomena, we construct an analytical turbulence model with variable energy flux that arises due to the Lorentz-force induced dissipation. The energy spectra computed using our model for various interaction parameters are in qualitative agreement with earlier experimental and numerical results.


Present endogenous degrading enzymes (e.g., proteases, etc.) in order to reduce the activity of lowering the pH of the composition, reducing the moisture content, during and / or composition adding water substitutes provide an amount stabilized by increasing the demineralized bone matrix (DBM) or other substrate compositions of heavy water to. It stabilized DBM composition hydrated form, may be stable up to one year at room temperature at acidic pH. DBM composition acidification include stabilizers, for example, heavy water, water substitute, polymers, protease inhibitors, glycerol, the addition of such hydrogels can be further stabilized. The present invention is also a process for preparing stabilized osteoinductive matrix composition of the present invention, to provide a test method and use.


Insulated DC-DC switching power supplies have been using a magnetic coupling method using a transformer for several decades. Transformers have excellent properties as a material that can change the voltage while insulating. On the other hand, it can be considered that there is a limit to the reduction in size and weight with increasing switching frequency. Therefore, we are interested in the insulation type converter by the capacitor coupling. The principle of the capacitor insulation method was introduced in 1994, but it was pointed out that the problem of noise that occurs when the power device is turned on and off. After that, a case where noise was suppressed by using a series resonant circuit of a capacitor and an inductor was reported. However, it had no means to control the output voltage, and had the problem that fluctuations in the input voltage would directly cause fluctuations in the output. Therefore, we maintain "resonance state" by providing "two sets of LC resonance tank circuits corresponding to the resonance frequency" and changing the operating frequency for ON width pulse of fixed width (pulse frequency modulation or pulse density modulation). We propose that the output voltage can be controlled while. The voltage control characteristics are analyzed using Spice Simulation, and the Co-relation with the experimental value is confirmed. By using frequency/density modulation, the inverter is always switched at the current zero crossing point, enabling Noiseless switching. Regarding the possibility, we will analyze the switching characteristics due to the deviation from the resonance point by using ADS; Electronic Design Automation tool, for the noise that may occur in the actual PCB (circuit pattern), and show the results.


The article presents the results of a sociological study – an expert survey on the problems of selfdevelopment of the municipalities of the Far North and the Russian Arctic. Comparisons, generalizations on the most significant issues characterizing the dynamics of self-development of a number of municipalities of the specified territory are made. The constancy of the problems limiting the self-development of municipalities was revealed: lack of financial resources and budget revenues, logistical difficulties due to the focality of settlement and poor transport accessibility, problems of employment and training of in-demand personnel. The importance of expert opinions on the assessment of urgent problems for the development and adjustment of appropriate management decisions is shown.


This paper documents the change in educational achievement differences between native and foreign background students between the ages of 10 and 15, as they progress from primary to secondary education. We examine three cohorts of students in a number of Western European and traditional English-speaking immigration countries using combinations of PIRLS, TIMSS and PISA survey data. While the performance of students with mixed parents is not markedly different from native students', foreign background children—both first- and second-generation—exhibit a large achievement gap at age 10 in continental Europe, even when accounting for observable differences in socio-economic characteristics. The gap tends to narrow down by age 15 in reading, but no catching up is observed in mathematics. By contrast, we do not find significant differences between the academic achievements of immigrant children and their native-born peers in traditional immigration countries.


This article considers the philosophical underpinnings that have shadowed the emergence of focus group methods as a counterpoise to positivist research design. Examples of the application of focus group methods are drawn from two studies where the voices of marginalized groups were facilitated: 1) focus groups with patients diagnosed with personality disorder; and 2) focus groups with gypsy travellers. In both groups there were varying degrees of coherence in communication although particular attention here is paid to the role of dissonance and `negative dialectics' in the formation of opinion. Data generation in focus groups is considered in relation to group size, structure and clinical techniques.


The Australian schooling system has become increasingly segregated and unequal, which is identified in an increased gap between the rich and poor and the differences in public and private schools. Some years ago the Australian government attempted to provide support to refugee and immigrant students under the New Arrivals Program. English as a second language (ESL) programs could be made effective with the financial allocation being three times more than the amount currently provided through federal sources.


There are number of welding methods available for welding materials such as shielded metal arc welding, Gas metal arc welding, Flux cored arc welding, submerged arc welding, electro slag welding, electron beam welding, and Gas Tungsten arc welding methods. The choice of the welding depends on several factors; primarily among them are the compositional range of the material to be welded, the thickness of the base materials and type of current. Tungsten inert gas (TIG) welding is the most popular gas shielding arc welding process used in many industrial fields. Other arc welding processes have limited quality when they are compared to TIG welding processes. However, TIG welding also needs improvements regarding spatter reduction and weld quality of the bead. Shielding gas in TIG welding is desirable for protection of atmospheric contamination. TIG welding process has the possibility of becoming a new welding process giving high quality and provides relatively pollution


Significance The transcription coactivator LEDGF/p75 contributes to regulation of gene expression by tethering other factors to actively transcribed genes on chromatin. Its chromatin-tethering activity is hijacked in two important disease settings, HIV and mixed-lineage leukemia; however, the basis for the biological regulation of LEDGF/p75's interaction to binding partners has remained unknown. This has represented a gap in our understanding of LEDGF/p75's fundamental biological function and a major limitation for development of therapeutic targeting of LEDGF/p75 in human disease. Our work provides a mechanistic understanding of how the lens epithelium-derived growth factor interaction network is regulated at the molecular level. Lens epithelium-derived growth factor/p75 (LEDGF/p75, or PSIP1) is a transcriptional coactivator that tethers other proteins to gene bodies. The chromatin tethering function of LEDGF/p75 is hijacked by HIV integrase to ensure viral integration at sites of active transcription. LEDGF/p75 is also important for the development of mixed-lineage leukemia (MLL), where it tethers the MLL1 fusion complex at aberrant MLL targets, inducing malignant transformation. However, little is known about how the LEDGF/p75 protein interaction network is regulated. Here, we obtained solution structures of the complete interfaces between the LEDGF/p75 integrase binding domain (IBD) and its cellular binding partners and validated another binding partner, Mediator subunit 1 (MED1). We reveal that structurally conserved IBD-binding motifs (IBMs) on known LEDGF/p75 binding partners can be regulated by phosphorylation, permitting switching between low- and high-affinity states. Finally, we show that elimination of IBM phosphorylation sites on MLL1 disrupts the oncogenic potential of primary MLL1-rearranged leukemic cells. Our results demonstrate that kinase-dependent phosphorylation of MLL1 represents a previously unknown oncogenic dependency that may be harnessed in the treatment of MLL-rearranged leukemia.


Thecommunication of research findings is one of our most important functions. Not communicating research findings can be harmful in many ways. Publication bias is a well-known phenomenon that affects cancer epidemiology, biomarker research, and cancer prevention. As these areas grow, along with the


Some years ago, a colleague from another institution told me how much she was looking forward to screening Nasser 56 in her introductory Middle East history course. Students had just finished reading about the Nasser era, and the screening of Muhamad Fadel's stylish biopic starring the charismatic film star Ahmed Zaki would serve as an enjoyable way to round out the unit. I was surprised, not at my colleague's use of the film in her class, but at her timing. Released in 1996, Nasser 56 is very much the product of the Mubarak era. It offers rich opportunities to discuss the particular challenges Egypt faced in the 1990s and how this nostalgic look back at a triumphant moment in Gamal Abdel Nasser's (Jamal ʿAbd al-Nasir's) presidency was marshalled to animate an economically and politically fraught period. Its celebration of ʿAbd al-Nasir as an effective and caring patriarch to the nation could be interpreted as an endorsement of Egypt's authoritarian political system. However, the film is less useful as an explication of ʿAbd al-Nasir as a political figure, or of 1950s Egypt.


Summary The definitions of thrusts and nappes are discussed and the criteria used to define these structures are analysed. A 'thrust fault' is defined as a map-scale contraction fault. A 'thrust nappe' is an allochthonous tectonic sheet which has moved along a thrust fault. Suggested definitions are also given for, a fold nappe; extension fault; contraction fault; listric normal fault; reverse listric fault; klippe; tectonic slide; ramps and flats; duplex structure; blind thrusts.


Computational optical scanning holography (COSH) is one of the single-pixel incoherent digital holographic techniques; therefore, three-dimensional fluorescent objects can be measured as a digital hologram with a single-pixel detector. However, due to the requirement of a phase-shifting method to remove unnecessary components from holograms, the number of measurements of COSH is larger than the number of pixels. To reduce the number of measurements, the spatially divided phase-shifting method has been proposed. Similar to the parallel four-step phase-shifting digital holography, the spatially divided phase-shifting method can obtain four phase-shifted holograms simultaneously. However, the spatially divided phase-shifting method has a problem in that the spatial resolution is lower than the original COSH. In this paper, a spatially divided two-step phase-shifting method is proposed to improve spatial resolution. The numerical evaluation results indicate the feasibility of the proposed method. In addition, the proposed method is applied to microscopy for proof of principle experiment. The experimental results indicate the proposed method improves the image quality compared with the conventional spatially divided four-step phase shifting method.


These Adaptive inverse compensation is adopted to eliminate the hysteresis nonlinearity of piezo-actuator in active control system. The adaptive control law based on grads method is obtained with Prandtl-Ishlinskii model. It is proved that when Prandtl-Ishlinskii model is used, results of compensation have no contact with slopes under the assumption that backlash model has a symmetry structure and backlashes as well as slopes are all proportional with each other. As only proportion of reference input and output is related with slopes, the estimated parameters are reduced to only one. The results of simulation indicated that compensation effect of adaptive inverse control to hysteresis nonlinearity was much better when signal frequency was low.


Despite sexuality education in school contexts being a highly politicized and ideologically fueled conversation, discussions of the specific needs of disabled students are often silenced, in particular for those who might be accessing special education programming. In this paper, we provide a call to action to explicate the crucial importance of addressing both ableist attitudes and constructions embedded within conversations of childhood sexuality and sexuality education, as well as policy and curriculum change to create more inclusive sexuality education approaches for disabled students and learners in Canadian provinces and territories. Many Canadian provinces do not mention disability or accommodations for disabled learners in their sexuality education curricula and all provincial curricula do not currently meet requirements set by internationally governing human rights policies. As such, this paper aims to bring to attention the different ways in which current school-based sexuality education is failing the human rights of disabled learners in Canadian schools and how sexuality education can be rethought through a social justice framework to ensure that the needs of all learners and that systems of inequality, such as ableism and heterosexism, are addressed in school contexts. Specific recommendations for policy and professional practice are provided to direct educators, policy-makers, and curriculum developers towards providing more inclusive sexuality education.


This paper presents the results of a numerical non-linear finite element modeling of the response of reinforced concrete slabs to the blast loads. A concrete slab with conventional reinforcement was analyzed using multi-degrees of freedom finite element model. A single degree of freedom model was also used in the analysis for comparison. The blast load was modeled as a tri-angular pressure load and distributed uniformly within the slab surface. The nonlinear behavior of concrete and reinforcing steel was taken into account in the finite element model. The effects of applying the relatively high dynamic load with a short duration on the material properties were taken into account by means of dynamic increasing factors. It has been found that the single degree of freedom procedure which is adopted in technical manual "Structures to Resist the effects of Accidental Explosions "TM51300 gives conservative results compared to finite element procedure. Also the displacement –time history for the slab been plotted and it has been found that it was similar to the expected time history illustrated in literature.


SINCE PUBLICATION of a descriptive account of the species of Conus in Hawaii (Kahn, 1959) several additional species have been collected, and study of additional material has led to the discovery of a major error in the previous report. We correct this error here, discuss the recently discovered species, and provide new information on appearance of soft parts, maximum size, and vertical distribution of several species. The Pele Expedition of May-Sep 1959 dredged from sites off Oahu and Maui much of the material reported on here. The descriptive terminology in this paper follows Cox (1960). Names of colors of shells are those of the Inter-Society Color CouncilNational Bureau of Standards (ISCC-NBS) (Kelly and Judd, 1955), obtained with the standards of Ridgway (1912). Colors of soft parts in life are subjective and were not compared with standards.


Building on perspectives from sociology, criminology, and economics, this article reports findings from a randomized experiment undertaken with over 2,000 ex-offenders in the states of Texas and Georgia in which unemployment benefits were extended to individuals immediately upon release from prison. The analysis focuses on the endogenous relationships (over a one-year follow-up period) between these "transfer payments," unemployment, arrests for property and nonproperty crimes, and the resulting time spent in jail or prison. By and large, the hypotheses derived from a priori theory are supported by the data. (abstract Adapted from Source: American Sociological Review, 1980. Copyright © 1980 by the American Sociological Association) Ex-Offender Texas Crime Causes Poverty Socioeconomic Factors Unemployment Factors Employment Factors Adult Crime Adult Offender 07-02


On behalf of the Organizing Committee, it is my pleasure to warmly welcome you all to the 20th Symposium on Integrated Circuits and System Design (SBCCI2007) in the beautiful Rio de Janeiro, a city rich in culture and natural beauties.

SBCCI2007 is to be held at the Othon Palace Hotel, facing one of the most famous beaches in the world and Rio's best known postcards, Copacabana Beach. It is an ideal place to combine stimulating scientific meetings with leisure.

The technical program this year consists of 21 sessions that cover a broad range of technical subjects. I am very pleased that the response of the Integrated Circuits and Design Scientific Community confirmed the tradition of continued growth of the SBCCI conferences, reaching even more countries outside Latin America. A panel discussion on Government sponsored research and industry initiatives in Brazil, along with four plenary presentations are also planned. In addition to the regular technical program, 5 specially organized tutorials are scheduled on Monday, September 3, preceding the start of the regular program.

Besides hard work, a conference is also a good opportunity to travel and learn more about the world countries and peoples. A number of social events are planned throughout the conference, including a Welcoming Reception and a Banquet with great Brazilian food and music. Additionally, spouse and dependent activities are organized, and include bus tours to famous places such as the planet's largest urban forest, with an area of 3,300 hectares encompassing trees, belvederes, caves and waterfalls, the Sugar Loaf, and of course, the statue of Christ the Redeemer, which has just been chosen to be among the modern-day seven Wonders of the World.


Amends the Internal Revenue Code to exclude from gross income interest on industrial development bonds the proceeds of which are to be used to provide for the construction, reconstruction, erection, or acquisition of a beverage container facility used in connection with a law prohibiting or discouraging the sale of beverages in nonreturnable containers.


In this paper we provide a detailed description of the ground-state phase diagram of interacting, disordered bosons on a lattice. We describe a quantum Monte Carlo algorithm that incorporates in an efficient manner the required bosonic wave-function symmetry. We consider the ordered case, where we evaluate the compressibility gap and show the lowest three Mott insulating lobes. We obtain the critical ratio of interaction strength to hopping at which the onset of superfluidity occurs for the first lobe, and the critical exponents {nu} and {ital z}. For the disordered model we show the effect of randomness on the phase diagram and the superfluid correlations. We also measure the response of the superfluid density, {rho}{sub {ital s}}, to external perturbations. This provides an unambiguous characterization of the recently observed Bose and Anderson glass phases.


The mechanical limited slip differential (LSD) in vehicles is being replaced by the electromagnetic LSD because of its fast response and better active control characteristics. The coil housing made of STS 304 is one of the most important parts in the solenoid assembly of the electromagnetic LSD. High geometrical accuracy is a prerequisite for the manufacture of such coil housings, but precision machining is difficult because of the use of STS 304 thin plate and the variance in machining variables. The aim of this study is to optimize the mean and variance of the shape accuracy in the coil housing by finding a robust solution for the machining process conditions. The mean and standard deviation of the jaw contact pressure, cutting speed, and feed rate are considered to be the major parameters for minimizing the geometrical mean and variance. The response surface model based on the second-order Taylor series is combined together to minimize the mean and variance of the shape accuracy of the coil housing.


Purpose: Emergency departments have a basic role in saving the human life in any accidents. Developing an information system with an accurate documentation facilitates evaluating emergencies activities and providing quality care. The main objective of this study was to determine the rate of complete documentation and compliance of legal aspects in documentation of Emergency's Medical Records in teaching hospitals of Zabol University of Medical Sciences. Methods: In this descriptive-analytical research, 500 Emergency's Medical Records were selected by random sampling method. Two checklists were applied to gather all the information. First checklist measured completion of data element in Emergency's Medical Records forms and second checklist analyzed the legal aspect Compliance. Since the first checklist used the standard medical record`s data item of Ministry of health, it was validated. Reliability and validity of second checklist were verified by of medical records experts' opinions. The statistical significance was set to 0.05. The statistical package SPSS were used for the analysis (Chi-square test). Results: The amount of data recorded by physician, nurses, and reception staffs were 25.4, 52.6 and 67.1 percent, respectively. In general, legal aspect Compliance was 44.7 percent. Comparing hospitals` legal aspect Compliance ratio showed a statistically significant difference (P=0.0001). Conclusion: Our study showed that Emergency's Medical Records were incomplete and legal aspects were not complied in medical record documentation. These deficiencies lead to loss of patients' information. Therefore authorities, doctors, and medical experts should pay more attention to completeness of documentation of emergency's patient records in teaching hospitals of Zabol University of Medical Sciences.


of a lover of art..."2 This meeting halfway is potentially a great leveler, allowing people without money or academic credentials access to objects which otherwise require admission fees, travel expenses, or social connections. The Drexel Digital Museum is a searchable database of text and images concerning objects housed in the Drexel Museum and the College of Media Arts and Design at Drexel University in Philadelphia. The database is a joint project of the Colleges of Media Arts and Design and Information Science and Technology. At present the database includes only limited data for the Drexel


Swedish pupils' ability to profit mathematical education is often written about. Many pupils are said to have difficulties in mathematics and because of that they have difficulties reaching the goa ...


Simple Summary Central line-associated bloodstream infection (CLABSI) is among the most serious hospital-acquired infections that impose public health threats. Accordingly, the urgent need for a rapid identification method that can identify CLABSI pathogens and their resistance genetic markers is essential for the prompt initiation of adequate antibiotic therapy. This study aimed to evaluate the clinical performance of the BioFire FilmArray Blood Culture Identification 2 (BCID2) panel in the rapid identification of 33 microbial species and 10 antibiotic resistance genes in comparison to the VITEK-2 system, among 104 patients admitted to an ICU in an Egyptian tertiary care hospital with bloodstream infections (BSIs) within 48 h of a central line placement. In comparison to the VITEK-2 system, the BCID2 panel showed an overall sensitivity of 75.8% and an overall specificity of 98% in detecting microbial species. The sensitivity and specificity for detecting resistance genes by BCID2 were 90% and 99.6%, respectively. In conclusion, this study emphasizes the high sensitivity and specificity of the BCID2 as compared to the VITEK-2 system in the rapid and reliable microbial identification, as well as the accurate detection of various antibiotic resistance markers. Abstract Central line-associated bloodstream infection (CLABSI) is among the most serious hospital acquired infections. Therefore, the rapid detection of the causative microorganism is of crucial importance to allow for the appropriate antimicrobial therapy. In the present study, we analyzed the clinical performance of the BioFire FilmArray Blood Culture Identification 2 (BCID2) panel in the identification of 33 microbial species and 10 antibiotic resistance genes in comparison to the VITEK-2 system. A total of 104 blood specimens were included. The FilmArray BCID2 results were concordant with the VITEK-2 system in 69/97 specimens (71.1%). Non-concordance was either due to the detection of more pathogens by the FilmArray BCID2 23/28 (82%) or microbial species were misidentified 5/28 (18%). Hence, in comparison to the VITEK-2 system, the FilmArray BCID2 panel showed an overall sensitivity of 75.8% (95% CI, 66–83%) and an overall specificity of 98% (95% CI, 97–98.8%) in detecting microbial species. For the resistance genes, the FilmArray BCID was able to detect the presence of blaCTX-M gene in 23 Gram-negative isolates, blaNDM and blaOXA-48- like genes in 14 and 13 isolates, respectively. The mecA and mecC genes were found in 23 Staphylococcus species, while mecA, mecC and MREJ genes were found in 4 Staphylococcus aureus isolates. The sensitivity and specificity for detecting resistance genes by the FilmArray BCID2 was 90% (95% CI, 81.4–95%) and 99.6% (95% CI, 99–100%), respectively. As concluded, the present study emphasizes the high sensitivity and specificity of the FilmArray BCID2 in the rapid and reliable detection of different bacteria and fungi from positive blood culture bottles, as well as the accurate detection of various antibiotic resistance markers.


Williams et al. (1976) have provided useful confirmation of the effectiveness of bed rest in ensuring maximum retention ofisotope in a joint, particularly ofgold 198. One sentence in their article is perhaps misleading. It should be clearly understood that in only one of the publications that they quote were some patients not strictly rested in bed (Gumpel et al., 1973). In our single centre comparison of four yttrium 90 colloids (Gumpel et al., 1975) we compared the retention of citrate, ferric hydroxide, resin, and silicate, in randomly selected patients in identical conditions. Although our figures for retention of ferric hydroxide were not grossly different from those given by Williams et al., the variability of retention in the knee in individual patients was much greater with ferric hydroxide than with silicate. This is clearly shown in one figure in this paper and the results that they have quoted from a paper on chromosomal damage (Gumpel and Stevenson, 1975) are only a brief synopsis of that study. For this reason we chose to use yttrium 90 silicate rather than ferric hydroxide. J. M. GUMPEL Rheumatic Disease Study Group, Northwick Park Hospital, Watford Road, Harrow, Middlesex HAI 3UJ. References Gumpel, J. M., and Stevenson, A. C. (1975). Chromosomal damage after intra-articular rejection of different colloids of yttrium 90. Rheumatology and Rehabilitation, 14, 7-12. Gumpel, J. M., Williams, E. D., and Glass, H. J. (1973). Use of yttrium 90 in persistent synovitis of the knee. I. Retention in the knee and spread in the body after injection. Annals ofthe Rheumatic Diseases, 32,223-226. Gumpel, J. M., Beer, T. C., Crawley, J. C. W., and Farran, H. E. A. (1975). Yttrium 90 in persistent synovitis of the knee--a single centre comparison. The retention and extra-articular spread of four 90-U radiocolloids. British Journal ofRadiology, 48, 377-381. Williams, E. D., Caughey, D. E., Hurley, P. J., and John, M. B. (1976). Distribution of yttrium 90 ferric hydroxide colloid and gold 198 colloid after injection into knee. Annals ofthe Rheumatic Diseases, 35, 516-520.


Background: Nearly 35 million people are suffering from diabetes in India. The present trend in diabetes is escalating diabetes prevalence and earlier onset of type 2 diabetes in the adult population. Awareness is an important factor in the early diagnosis, adequate treatment and prevention of complications due to diabetes. This study was undertaken to assess the knowledge regarding different aspects of diabetes mellitus among college students.Methods: A cross-sectional study was undertaken with 348 college students of Latur City. The students were administered a 41 items, pre-tested, semi structured questionnaire assessing general and specific knowledge of diabetes like symptoms, causation, risk factors, complication, treatment, attitudes towards people with diabetes etc. The results were analyzed using Microsoft Excel software.Results: Excessive tiredness, non healing wounds, excessive sweating and hunger were mentioned as symptoms of diabetes by 82.47, 73.85% and 72.70% subjects respectively. About (57.76%) study participants were aware of diabetes as a rising problem and only (8.33%) students had correct knowledge of the prevalence. Only (27.30%) were aware that genetic factors are reason for the causation of diabetes. As much as 85.91% subjects stated that blood and urine tests are done for diagnosing diabetic persons. Common complications not identified by the study subjects were impotence (68.39%), stroke (64.65%), ulcer on foot (54.31%), and repeated skin infections (53.16%).Conclusions: Specific knowledge about diabetes is poor among the degree college students, hence appropriate activities to increase awareness about diabetes is the need of the hour.


This article compares the predictive performance of ARIMA and artificial neural networks. Production forecasts of wind power to produce electricity in the field of "Kabertne" (70 km north of the State capital of the Adrar, in southern Algeria), the results show that ANN mode better predict than ARIMA model, according to the criteria of the MAE, RMSE,
and MAD. overall ANN are the best model and can be used as an alternative method for the prediction of wind energy production. The actual empirical results with data indicate
that the proposed model can be an effective way to improve the accuracy of forecasting by artificial neural networks. Therefore, it can be used as an alternative model appropriate for the operational forecasting, especially when forecasts more precision is needed.


We can overcome the pessimism in worst-case routing latency analysis of timing-predictable Network-on-Chip (NoC) workloads by single-digit factors through the use of a hybrid field-programmable gate array (FPGA)–optimized NoC and workload-adapted regulation. Timing-predictable FPGA-optimized NoCs such as HopliteBuf integrate stall-free FIFOs that are sized using offline static analysis of a user-supplied flow pattern and rates. For certain bursty traffic and flow configurations, static analysis delivers very large, sometimes infeasible, FIFO size bounds and large worst-case latency bounds. Alternatively, backpressure-based NoCs such as HopliteBP can operate with lower latencies for certain bursty flows. However, they suffer from severe pessimism in the analysis due to the effect of pipelining of packets and interleaving of flows at switch ports. As we show in this article, a hybrid FPGA NoC that seamlessly composes both design styles on a per-switch basis delivers the best of both worlds, with improved feasibility (bounded operation) and tighter latency bounds. We select the NoC switch configuration through a novel evolutionary algorithm based on Maximum Likelihood Estimation (MLE). For synthetic (RANDOM, LOCAL) and real-world (SpMV, Graph) workloads, we demonstrate ≈2–3× improvements in feasibility and ≈1–6.8× in worst-case latency while requiring an LUT cost only ≈1–1.5× larger than the cheapest HopliteBuf solution. We also deploy and verify our NoC (PL) and MLE framework (PS) on a Pynq-Z1 to adapt and reconfigure NoC switches dynamically. We can further improve a workload's routability by learning to surgically tune regulation rates for each traffic trace to maximize available routing bandwidth. We capture critical dependency between traces by modelling the regulation space as a multivariate Gaussian distribution and learn the distribution's parameters using Covariance Matrix Adaptation Evolution Strategy (CMA-ES). We also propose nested learning, which learns switch configurations and regulation rates in tandem. Compared with stand-alone switch learning, this symbiotic nested learning helps achieve ≈ 1.5× lower cost constrained latency, ≈ 3.1× faster individual rates, and ≈ 1.4× faster mean rates. We also evaluate improvements to vanilla NoCs' routing using only stand-alone rate learning (no switch learning), with ≈ 1.6× lower latency across synthetic and real-world benchmarks.


A learning management system is an educational tool employed in higher education to organize, document, track, report, and deliver courses. Selecting the appropriate learning management system is a critical decision for a university. This study explores the usability of two leading systems, Blackboard and Canvas, from the students' perspective. The goal is to gather and analyze user preferences in order to select an appropriate learning management system. Data was collected through surveys of student's experience with the two learning management systems. The survey evaluated the ease of the following tasks: finding course documents, viewing grades, ease of navigation, intuitiveness, and communicating with professors. A usability study was also conducted on both learning management systems. The information was combined to provide an overall ranking of the learning management systems.


Abstract At present cod liver oil is the most common source of vitamin D for chicks which do not have access to direct sunshine. Since the vitamin D potency of different cod liver oils varies, safety demands the use of biologically tested oils, which are rather expensive. It seemed desirable to determine the value of cod liver oil stearin as a preventive of rickets in growing chicks, since it offered possibilities for an economical source of vitamin D. Stearin1 is the term which is used to designate the mixture of fats which is removed from crude cod liver oil during its preparation for human consumption. The crude oil is chilled to about 20° F2, at which temperature these fats solidify and are removed by filtering. Crude cod liver oil, on the average, contains about 20 per cent of stearin3; but this amount varies to some extent, depending upon the condition of . . .


Abstract This study examines the value relevance of mandated disclosures by UK firms of the investor‐firm share of liabilities of equity‐accounted associate and joint venture investees. It does so for the six years following the introduction of FRS 9: Associates and Joint Ventures, which forced a substantial increase in such disclosures by UK firms. Since the increased disclosure requirements were partly motivated by concern that single‐line equity accounting concealed the level of group gearing, and in light of previous US results, it is predicted that the mandated investee‐liability disclosures have a negative coefficient in a value‐relevance regression. The study also examines whether value‐relevance regression coefficients on investee‐liability disclosures are more negative for joint ventures than for associates and whether they are more negative in the presence of investor‐firm guarantees of investee‐firm obligations than in the absence of such guarantees. The study reports that the coefficient on all investee‐liability disclosures taken together has the predicted negative sign, and is significantly different from zero. It finds little evidence that the negative valuation impact of liability disclosures is stronger for joint venture investees overall than for associate investees overall, or stronger for guarantee cases overall than for non‐guarantee cases overall. There is, however, some evidence that the impact for joint venture guarantee cases is stronger than that for joint venture non‐guarantee cases and stronger than that for associate guarantee cases.


Ideology in context human resources in the context of business strategy human resource strategies in the Chinese context the role of the HR function in foreign invested enterprises the greatest directness is flexible-compatible paradigms.


Objective To evaluate the role of gene CCR5 on donor cells in models where intensive preconditioning of the recipient occurs,thus provide the scientific evidence for clinical experience of allo-HSCT.Methods Lethally irradiated BALB/C mice received C57BL/6 mice is allogeneic bone marrow transplants.We divided mice into 4 groups according to receiving variant donor cells: B6 CCR5 KO group,receiving C57BL/6 CCR5~(-/-)mice bone marrow cells and splenocytes;B6 WT BMC group,receiving C57BL/6 mice bone marrow cells and splenocytes;B6 CCR5 KO BMC group,receiving C57BL/6 CCR5~(-/-) bone marrow cells alone;B6 WT BMC group,receiving C57BL/6 mice bone marrow cells alone.Results Compared to B6 WT group,B6 CCR5 KO group succumbed to acute GVHD at an accelerated rate.Donor CD8~+ T cells expanded to a significantly greater extent in recipients of CCR5 KO vs WT control cells.T cells recovered from recipients of CCR5 KO cells roduced more IFN-γ and TNF-Αand proliferated to a T-cell mitogen at a significantly greater level than T cells from recipients of WT cells,indicating that CCR5 plays a role in downregualting donor alloreative CD8~+ T-cells expansion.Histological assessment of the mice indicated pathological lesions in the kidney and a greater degree of liver pathological changes in mice that received CCR5 KO donor grafts.Conclusion The absence of gene CCR5 on donor cells results in increased GVHD and donor CD8~+ T cells as well as hepatic and renal lesions in allo-HSCT,which indicated gene CCR5 is very important in allo-BMT.


DURING the two year period between July 1951 and July 1953, 546 patients were admitted to the enlisted men's neurosurgical ward at the United States Naval Hospital, National Naval Medical Center, Bethesda, Maryland. Craniocerebral injuries accounted for 222, or 40.6 per cent of all admissions. Open craniocerebral injuries (60 patients) were not as frequent as the closed type which occurred in 162 patients. The majority of these craniocerebral injuries were sustained as a result of automobile mishaps. Forty-three of the 162 patients with a closed head injury were studied. They had no evidence of a fracture through the calvarium or base of the skull on x-ray examination; there was a period of unconsciousness greater than five minutes; a diagnostic lumbar puncture was performed, with a careful manometric study and biochemical determinations; and a complete neurologic examination was performed for all patients under study. Lumbar punctures were done with the patient in the lateral position, and the cerebrospinal fluid was sent to the laboratory immediately for examination. One of the most difficult problems was an accurate determination of the period of unconsciousness; in most instances estimates were recorded, having been verified by information from relatives, police, witnesses to the accident, and other emergency service personnel who might have seen the patient first. In none of the patients did cerebrospinal fluid and blood escape from the nose, ears, or nasopharynx.


The objective of research is to estimate efficiency concerning laser ablation of leukoplakia of urinary bladder at women with chronic relapsing cystitis. Patients and methods. 124 patients (women) with the diagnosis of leukoplakia of urinary bladder were performed an ablation of mucous, changed by the high-energy laser by «Lahta-Milon» device (Russia) with wavelength of 0,81 microns and power output of 16 W. Efficiency of treatment was estimated in 7 days, 1, 6 and 12 months after the carried-out operative measure. Results. The laser ablation of leukoplakia of urinary bladder leads to permanent decrease of pains in suprapubic area and dysuria, normalization of urodynamical indicators. In 6 months after operation the frequency of emiction and intensity of pain syndrome decreased in comparison with initial indicators in 1,7 and 2,3 times respectively. Conclusion. Minimum surgical trauma, good hemostasis, lack of intraoperative complications, fast purification of mucous in urinary bladder from a crust, short period of postoperative aftertreatment are the main advantages of laser ablation of leukoplakia of urinary bladder.


THE CAUSES OF THE ACCIDENT WERE EXAMINED BY A SPECIAL COMMITTEE. THE LESSONS TO BE DERIVED FROM THE INVESTIGATION ARE OUTLINED, AND ATTENTION IS DRAWN TO THE NEED FOR GREATER CARE IN THE DESIGN AND CONSTRUCTION OF LARGE RIVER BRIDGES, PARTICULARLY AS REGARDS STRESSES DURING CONSTRUCTION AND ERECTION.


We describe a topic-based multidocument sentence extractor developed for the DUC 2005 competition. The system has been designed for the real task of producing summaries given an information need expressed as a set of questions. The implementation of the system takes advantage of an in-house summarization toolkit and available natural language processing technology.


Chomsky, Noam. 2001. Derivation by phase. In Michael Kenstowicz (ed.), Ken Hale: A life in language, 1–52. Cambridge, MA: MIT Press. Chomsky, Noam. 2008. On phases. In Robert Freidin, Carlos P. Otero & Maria Luisa Zubizarreta (eds.), Foundational issues in linguistic theory: Essays in honor of Jean-Roger Vergnaud, 133–166. Cambridge, MA: MIT Press. Hale, Mark & Charles Reiss. 2000. 'Substance abuse' and 'dysfunctionalism': Current trends in phonology. Linguistic Inquiry 31, 157–169. Marvin, Tatjana. 2002. Topics in the stress & syntax of words. Ph.D. dissertation, MIT. Mester, R. Armin. 1994. The quantitative trochee in Latin. Natural Language & Linguistic Theory 12, 1–61. Samuels, Bridget. 2011. Phonological architecture: A biolinguistic perspective. Oxford: Oxford University Press. Samuels, Bridget. To appear. Consequences of phases for morphophonology. In Ángel J. Gallego (ed.), Phases: Developing the framework. Berlin: Mouton de Gruyter. Scheer, Tobias. 2010. A guide to morphosyntax–phonology interface theories: How extraphonological information is treated in phonology since Trubetzkoy's Grenzsignale. Berlin: Mouton de Gruyter. Vaux, Bert. 2008. Why the phonological component must be serial & rule-based. In Bert Vaux & Andrew Nevins (eds.), Rules, constraints, and phonological phenomena, 20–60. Oxford: Oxford University Press.


This study focused on a high photo catalyst activity of TiO2 in addition to bleaching of different types of dyes. Titanium dioxide Nano particles were successfully synthesized by sol Gel method, then the gel has been dried at 400°C to obtain TiO2 Nano powder. The synthesized Nano powder has been characterized by X-ray diffraction (XRD), Scanning Electron Microscope (SEM), Ultraviolet spectroscopy (Uv-Vis). A system of photocatalytic with UVlamp (365nm) to activate a thin layer of TiO2 particles on glass substrate was set up, and the effect of activated TiO2 on degradation of methyl orange and Eriochrom black T as a model of organic pollutants were investigated in ppm concentration over period time of 6 hours. The results shown that Titanium dioxide nanoparticle shows a high efficiency to degradation of dyes. The highest percentages were 95.69%, 97.96% for MO and EBT respectively.


The analysis of variance showed a significant (P less than or equal to 0.01) effect of the presence of pathogenioc bacteria in the udder on lactose content in milk. The relationship between lactose level and milk yield was significant (P less than or equal to 0.05).


The unsaturated complex [Mo2Cp2(μ-COMe)(μ-PCy2)(μ-CO)] (1) reacts with the solvate manganese complexes [MnL(CO)2(THF)] (L = Cp, η5-C5H4Me) rapidly at room temperature in toluene solution to give the corresponding electron-precise clusters [MnMo2Cp2L(μ3-COMe)(μ-PCy2)(CO)4] (Mo−Mo = 2.986(1) A when L = Cp), which follow from the addition of the manganese fragment to compound 1 and further spontaneous carbonylation. In contrast, the incorporation of the group 8 metal fragments M(CO)4 occurs selectively either at room temperature (reaction with [Fe2(CO)9]) or under photochemical activation (reaction with [Ru3(CO)12]) to give the 46-electron derivatives [Mo2MCp2(μ3-COMe)(μ-PCy2)(CO)5] (M = Fe, Ru), which follow from the addition of the M(CO)4 fragment to compound 1 and carbonyl migration from M to molybdenum. Simple addition of a metal fragment to the triple intermetallic bond of 1 is observed in its reaction with CuCl, which gives the unsaturated derivative [CuMo2ClCp2(μ3-COMe)(μ-PCy2)(μ-CO)]. Compound 1 can ...


Abstract A chemo‐ and biocatalytic cascade approach was applied for the stereoselective synthesis of hydroxy ketones and the corresponding 1,3‐diols. A new class of tridentate N,N,O ligands was used with copper(II) complexes for the asymmetric β‐borylation of α,β‐unsaturated compounds. The complex containing ligand L5 emerged as the best performer, and it gave the organoborane derivatives with good ee values. The corresponding keto–alcohol compounds were then bioreduced by yeasts. The biotransformation set up with Rhodotorula rubra allowed (R)‐keto–alcohols and (S,S)‐diols to be obtained with up to 99 % ee and up to 99 % de in favor of the anti enantiomers.


Introduction Many students lack the political sophistication necessary to interpret the underlying messages that are a basic ingredient of political advertising. This lesson plan will help students understand that political advertisements often appeal to people's base emo tions, and that they sometimes contain false or misleading informa tion. This lesson plan will also give students the skills they need to examine political advertisements from an analytical point of view. Prior to class the teacher should videotape several political ads. The more ads that can be taped the better. The ads should include candidates for as many offices as possible and represent both the Republican and Democratic parties. Taping the ads can be done easily while watching television. Many ads will be run at the hour and half-hour. Put the VCR in the "record" mode and "pause" it until a political ad is broadcast. Show the political ads to the students in class and have them fill out the worksheet after each ad is viewed (you may want to do this activity in groups). After each ad is shown have the students give their conclusions about the ad based on their worksheet data. As a follow-up for this assignment, have students (either in class or for homework) do research on a political ad to see if the claims made for the candidate, or against his opponent, are valid. Using the Worksheet Name or number each political advertisement that you show so that students can easily identify the ad. Many ads will not mention the party that the candidate belongs to; lead a discussion on why this is so. (The candidate wants "cross-over" voters and does not want to antagonize voters who might like his ideas but belong to the other party; voters to whom party identity is important will either already know the candidate's party or will be contacted by party workers who are "getting out the vote"). Discuss the issues that the ad is referring to. Does the ad relay a message that is not explicitly stated? (The "Willie Horton" ad is the most famous example of this technique). Ask whether the ad is primarily for the candidate (a positive ad) or is it primarily against his opponent (a negative ad). Elicit feelings from the class on which type of ad they believe is the most effective and why they feel the way that they do. The student should evaluate the ad for its effectiveness. For


The article analyzes the views of the representative of the Russian sociological school of law, a supporter of the ideas of the right state and civil society B. A. Kistyakovsky on the problem of law and social justice. It is established that social justice, according to the scientist, could not exist outside of a legal society with a developed legal culture, values and freedom of choice. It is doctrinally justified that the true existence of law in the concept of B. A. Kistyakovsky was not in formal normativism, but in the consciousness of the whole society, which influenced the knowledge of law as a social phenomenon, the so-called «just law».


to April 1920. This was when the treaty was really hammered out. More of the book concerns this period than the spring of 1919, dramatic though that was because of Wilson's presence and the arguments among the Big Three or Four. The San Remo conference is correctly described as mostly a rubber stamp. Helmreich is usually easy to read. It is unfortunate that the opening page gives an outlandish spelling of Kut-al-Amara, and that the neobarbarisms of "mitigate" for "militate" and "flaunt" for "flout" have been allowed to creep into a scholarly work. . Two of the author's judgments may be questioned. He believes that the negotiations occasionally were influenced by a correct assessment of the growing Turkish nationalist movement; the Sevres terms make this seem debatable. He also believes that Curzon's idea of splitting Constantinople from the rest of Turkey would have saved much later anguish; yet it is hard to conceive of a viable Constantinopolitan state of any sort, or even of a durable consensus among great and small powers on its future. But generally Helmreich is judicious in his observations and conclusions. He shows clearly how great-power and imperialist interests produced an unenforceable peace that disregarded the wishes of the peoples of the area. Balfour's remark in the following colloquy gives the tone of the peacemaking. Montagu: "Let us not, for Heaven's sake, tell the Moslem what he ought to think, let us recognize what they do think." Balfour: "I am quite unable to see why Heaven or any other Power should object to our telling the Moslem what he ought to think." Or—one might add—the Armenian, the Bulgarian, the Maronite, or the Greek Orthodox.


Objective: To identify the type of family bond of the elderly living in long-term care institutions. Method: This is a literature review through research in digital databases such as the Virtual Health Library (VHL), LILACS, MEDLINE, SCIELO, based on standardized and available descriptors, in studies published in the last 5 years. Results: After the analysis, 12 articles were included in the review, which discuss the institutionalization of the elderly and their feelings. Conclusion: Many family ties may have been broken in the past and not necessarily in old age, leading to the institutionalization of the elderly. But if these bonds are strengthened, they can provide the elderly a life with dignity and with guaranteed rights.


Paprika Oleoresin (PO) is a widely used natural colour in the food industry and microencapsulation by spray drying has served to be a successful option to prevent colour degradation of these compounds. This research was focused on evaluating the enhancement of physicochemical properties by using a blend of Gum Arabic (GA) and Orangepeel nanofibers (OPNF) as encapsulants. The addition of nanofibers to polymers resulted in superior properties, characterised by mechanical properties and SEM analyses. The wall material (GA:OPNF) was tested for different proportions (50:50, 60:40, 70:30, 80:20) by comparing encapsulation efficiency and moisture content. The best encapsulation efficiency was exhibited at 80:20 but moisture content was lowest at 70:30. Hence the latter was chosen for the evaluation of physicochemical properties such as water activity, hygroscopicity, caking, solubility, density, flowability and colour. The outcomes suggest that the proposed nanomaterial from orangepeel could serve as a potential supplement to the conventional encapsulant.


The present invention relates to a multiphase flow positron tomographic imaging apparatus in a pipeline, the apparatus using the electron-positron annihilation produces a pair of 511keV gamma ray energy may conform to the tomographic imaging means, for the oil pipeline in multiphase flow metering online tomography function. The apparatus comprises a gamma-ray detector arrays with high accuracy a plurality of sets of parallel arrangement of the specific spatial structure of the positron radiation source and the shield, and the binding function of the image processing oil can be acquired only at a single radiation source, gas phase fraction of the multiphase flow mixture of water and the like. A plurality of sets of the detector array precision design greatly improves the accuracy and applicability of the multiphase flow metering multiphase flow in various flow patterns of flow pattern. Image information it produces fluid will greatly enrich the basic data for the oil and gas industry oil and gas metering information and to provide more effective reservoir management and production optimization.


The air oxidation of poly-p-xylylene films was studied at temperatures between 125 and 200°C. The oxidation kinetics were obtained from neutron activation (NA) oxygen analyses and infrared (IR) Spectroscopy. A correlation between the NA oxygen analyses and mechanical properties indicated that the amount of oxygen incorporated into these polymers before a significant degradation mechanical properties is about 1000 ppm for poly(dichloro-p-xylylene) and 5000 ppm for poly(monochloro-p-xylylene) or poly-p-xylylene. The activation energy for the oxidation of these polymers was about 30 kcal/mole. Long-term-use (100,000 hr) temperatures were also estimated for each of the poly-p-xylylenes studied. The 100,000-hr maximum continuous-use temperature is 112°C for poly(dichloro-p-xylylene), 72°C for poly(monochloro-p-xylylene), and 57°C for poly-p-xylylene.


The Atlantic forest is a terrestrial biome that extends along the Brazilian coast and has been subject of intense deforestation for decades. There are presently several efforts to try to preserve the flora and fauna of what remains from this region (e.g., Coco et al. 2014, Maciel-Silva et al. 2014, Missagia et al. 2014), but several questions on how the distinct floristic units of this biome are structured is still to be understood. In this issue of the AABC, Saiter et al. (2015) have studied the occurrences of different tree species and related them to distinct geoclimatic data in the Rio Doce River. As known, geographic distribution of plants is highly complex and there are several variables to be taken into account (e.g., Rizzini 1997, Legendre and Legendre 2012). With this study, Saiter et al. (2015) have provided a better definition of several floristic units and aimed to establish better parameters that could help in the development of more effective conservation measurements. However, as everyone knows, a recent incident in the town of Mariana (Minas Gerais State) where a dam of a mining company failed caused serious effects on the biota of this area. Perhaps follow-up studies of the work of Saiter and colleagues might be paramount to revise several conservation actions in this region.


Weidentified andmappedtheregions responsible forneutralization inthehumanparvovirus B19structural protein byusing region-specific humanantibodies derived fromseropositive blooddonors. Theregion-specific antibodies were purified byusing affinity columns coupled withsynthetic peptides ofthehydrophilic regions including thes-turn structure deduced bythepredicted secondary structure ofVP2.Fifteen highly specific antibodies against thesynthetic peptides were obtained. Tenofthemwere abletoprecipitate theradiolabeled virus. Sixofthemproved tobeabletoprotect thecolony-forming uniterythroid cells inhumanbonemarrow cell cultures frominjury bythevirus. Thesequencesrecognized bythesixneutralizing antibodies were sites corresponding toaminoacids 253to272,309to330,325to346,359to382,449to468,and491to515from theamino-terminal portion ofVP2.Theseobservations suggest thattheneutralizing epitopes were distributed intheregion fromaminoacid253intheamino-terminal portion ofVP2tothecarboxyl terminus ofVP2.


OBJECTIVE
To determine the patient and hospital characteristics associated with severe manifestations of 'poor glycemic control'-a 'no-pay' hospital-acquired condition defined by the US Medicare program based on hospital claims related to severe complications of diabetes.

DESIGN
A nested case-control study.

SETTING
California acute care hospitals from 2005 to 2006.

PARTICIPANTS
All cases (n= 261) with manifestations of poor glycemic control not present on admission admitted to California acute care hospitals from 2005 to 2006 and 261 controls were matched (1:1) using administrative data for age, sex, major diagnostic category and severity of illness.

MAIN OUTCOME MEASURE(S)
The adjusted odds ratio (OR) for experiencing poor glycemic control.

RESULTS
Deaths (16 vs. 9%, P= 0.01) and total costs ($26,125 vs. $18,233, P= 0.026) were significantly higher among poor glycemic control cases. Risk-adjusted conditional logistic regression revealed that each additional chronic condition increased the odds of poor glycemic control by 12% (OR: 1.12, 95% CI: 1.04-1.22). The interaction of registered nurse staffing and hospital teaching status suggested that in non-teaching hospitals, each additional nursing hour per adjusted patient day significantly reduced the odds of poor glycemic control by 16% (OR: 0.84, 95% CI: 0.73-0.96). Nurse staffing was not significant in teaching hospitals (OR: 0.98, 95% CI: 0.88-1.11).

CONCLUSIONS
Severe poor glycemic control complications are relatively rare but meaningful events with disproportionately high costs and mortality. Increasing nurse staffing may be an effective strategy in reducing poor glycemic control complications particularly in non-teaching hospitals.


Negative of an art work depicting a soldiers being doctored under a tent. Govt. Collection # W.13.174.45. Data: On attached card- Abbott Collection, Paintings of Army Medicine, China-Burma-India. Watercolor, 22 x 18 by Howard Baer. Burma, 1944.


Simple Summary This experiment was conducted to investigate the effects of a high-dose vitamin E (VE) supplementation on rumen microorganisms and the blood metabolites of subacute ruminal acidosis (SARA) induced by a high-grain diet in dairy cows, and to explore the mechanism of action through the combined analysis of the microbiome and metabolome. Our studies indicate that a high dose of VE can alleviate a series of adverse effects caused by SARA. Abstract The aim of this trial was to assess whether the supplementation of vitamin E (VE) in high-concentrate diets could improve the fermentation and blood metabolism in the rumen of dairy cows, thereby modulating the degree of the subacute ruminal acidosis (SARA) response and improving the performance. Seven Holstein cows (four fitted with ruminal cannulas) were fed three diets (total mixed rations) during three successive periods (each lasted for 18 d): (1) the control diet (CON); (2) a high-grain (HG) diet, which was the control diet supplied with a 15% finely ground wheat diet (FGW); and (3) a high-VE diet (HGE), which was the control diet provided with a 15% FGW and 12,000 IU of VE/head per day. The results indicated that VE was able to alleviate the reduction in the dry matter intake (DMI) and milk fat yield in cows caused by HG diets. The supplementation of VE significantly reduced the levels of lipopolysaccharide (LPS), histamine (HIS), and the total volatile fatty acid (TVFA) in the rumen. The supplementation of VE observably increased the antioxidant capacity of the milk and plasma. In addition, VE markedly reduced the plasma levels of endotoxin, HIS, and pro-inflammatory factors. The supplementation of VE significantly enriched the differential metabolites of the purine metabolism, cysteine, methionine metabolism, and ABC transporter synthesis pathway in the serum. The supplementation of VE also significantly increased the relative abundance of Succiniclasticum and decreased the relative abundance of Treponema, thus reducing the production of TVFA in the rumen. In conclusion, considering that the cows in this trial had high ketone levels (BHBA > 2.3 mmol/L), we found that VE could improve the rumen fermentation and blood metabolism by modulating the relative abundance of rumen microorganisms, thereby mitigating a range of adverse effects caused by SARA.


Background . Zoster vaccine live (ZVL) is a live-attenuated vaccine for the preven- tion of herpes zoster (HZ) in individuals age 50 years and older, approved in May2006 and subsequently licensed in >50 countries. A review of spontaneous postmarketing (PM) adverse event (AE) reports following nearly 10 years of experience and >31 mil-lion doses distributed, worldwide, was conducted. Methods . The Merck AE Reporting System database was queried to identify all PM reports from 2 May 2006 to 1 November 2015 received from healthcare providers with a temporal association to ZVL. Results . A total of 21,833 reports containing 42,578 AEs were identi fi ed. The ma- jority of reports were from the US (85%), females (70%) and individuals ≥ 60 years of age (80%). Nine percent were from individuals<50 years of age and were primarily reports ofmedication errororofflabeluse. Ofthe reports withevent outcome reported at the time of the report, 60% reported recovery. Among the 21,833 reports, Oka/ Merck vaccine-strain varicella zoster virus (VZV), con fi rmed by PCR analysis, was reported in 12 reports. The most frequently reported AEs were injection site reactions (ISR) (n=8766; 21%) and HZ (n=3719; 9%). Median time to onset (TTO) from vac-cination to AE for ISR was 2 days. Of the 1691 reports of HZ with available VZV for the the 135 9 suggest an association between ZVL and re-currenceofHZO. (IMS) VZV IMS), Conclusion and vaccine-strain VZV have been reported individuals with DHZ, several immunosup- pressed contraindicated for The postmarketing safety pro fi le following nearly use consistent


UHVDC transmission system is characterized by transferring large amount of electrical power over long distance , which plays an important role in the west-to-east power transmission project. Since the underground current can reach several kA under UHVDC monopole operation, the safe and stable operations of grounding electrode are highly relative with nearby soil resistivity. This paper introduces porous media model and analyzes the influence of rising temperature around grounding electrode on soil resistivity. Based on researching soil conduction mechanism under DC, calculation formula for soil resistivity and the rule of DC density on soil resistivity are presented. Furthermore, the relationship between DC density and soil resistivity is obtained, which was demonstrated by current characteristics experiment of soil resistivity.


This presentation represents the outcomes of our study about the draft curriculum framework (DCF) for pre-university education. Findings from the research, our comments and conclusions are set forth in four sections, interconnected. The study summarizes the main features of the contemporary epistemological hypotheses. Although the new curriculum is not based on a particular theoretical approach, new ideas need to be drawn from it so far as the central idea of both is that students are architects and key actors in the process of building new knowledge and competencies. The accomplishment of this idea is related to the new meanings of "the curriculum" and "the competency". Key terms: Behaviourism; constructivism; curriculum; competency; content-based curriculum; competency-based approach. The starting point – a conceptual framework The conception of our curricular reform and the products (the DCF, gymnasium curricular documents, etc.) include new elements (cross-curricular skills, cross-cutting themes, etc.). Under these circumstances we can raise the question: "Does the proposed draft meet the requirements for the formation of the basic features of students? We based our response on the conceptual framework (Table 1). We analyzed the DCF, depending on the characteristics of the two approaches (inspired by distinct philosophical concepts) and conceptual networks of meanings "curriculum" and "competence". In this context, this information aims to promote a discussion about moving towards the competency-based curriculum which creates optimal conditions for people who want to know, do what is right and can also provide arguments why they do it. We should bear in mind that some of the features presented in columns of the conceptual framework are not simply alternatives to each other, but shifting poles. In practice, curriculum changes represent combinations of these characteristics or the balance between the poles. Thus, for example, the role of the teacher remains the key one, regardless of the type of approach applied in the educational process. 1. Pellumb Karameta, Executive Director, email@example.com


In this paper, we report the dynamic mechanical behavior of amorphous poly(vinyl chloride) (PVC) samples that have received three different thermal treatments:  (a) quenched from a temperature near calorimetric Tg, 80 °C; (b) quenched from a temperature above Tg, 90 °C; and (c) quenched from a temperature well above Tg, 130 °C. Dynamic mechanical measurements have been done at a heating process from about 50 to 115 °C, and from each run, we obtained tan φ and the storage modulus as functions of temperature for two frequencies, 10 and 1 Hz. The results clearly show that the quenching temperature has dramatic effects on the dynamic mechanical behavior of amorphous PVC and the range of physical aging is not limited to below the α-relaxation peak temperature (Tα).


(CrO3) [1333-82-0] CrO3 (MW 99.99)

InChI = 1S/Cr.3O

InChIKey = WGLPBDUCMAPZCE-UHFFFAOYSA-N

(C5H8N2) [67-51-6] C5H8N2 (MW 96.13)

InChI = 1S/C5H8N2/c1-4-3-5(2)7-6-4/h3H,1-2H3,(H,6,7)

InChIKey = SDXAWLJRERMRKF-UHFFFAOYSA-N

(oxidizing agent for alcohols;1 oxidant for saturated carbons α to unsaturation2-5)

Physical Data: see Chromium(VI) Oxide.

Solubility: sol dichloromethane; slightly sol ether and pentane.

Form Supplied in: formed in situ from widely available reagents.

Preparative Method: drying of the CrO3 over P2O5 is recommended; rapid addition of DMP (1 equiv) to a suspension of chromium(VI) oxide (1 equiv) in dry CH2Cl2 (−20 °C) results in a dark red homogeneous solution after 10 min; the solution is then treated with the organic substrate (0.05–0.5 equiv).1, 2

Handling, Storage, and Precautions: chromium salts are carcinogenic; this reagent should be used in a fume hood.


Symptoms of DHMN2 usually begin from the age of 10 to the middle of adulthood. Early signs of this disorder include clogging or weakness in the muscles of the toe and the next, the whole leg. The DHMN2 syndrome is caused by the mutation of the HSPB1 gene, which is positioned in the long arm of chromosome 7 as 7q11.23, and the HSPB8 gene, which is based on the long arm of chromosome 12, is 12q24.23.


Policymakers and academics often identify institutional boundaries as one of the factors that shape the capacity of jurisdictions to manage natural resources such as water, forests, and scenic lands. This article examines two key bodies of literature-common-pool resource management theory and local public economy theory-to explain how the boundaries of political jurisdictions affect natural resource management. Two empirical methods were used to test hypotheses from the literature, using a study of water management programs in California. The results demonstrate that institutional boundaries that coincide with natural resources are likely to be associated with the implementation of more effective resource management programs. At the same time, where jurisdictions can control through coordination, they can also facilitate more effective resource management where jurisdictions do not match resource boundaries. © 2004 by the Association for Public Policy Analysis and Management.


The wine industry impacts the environment due to its massive scale of production, distribution, and retail. Wine retailers' green purchasing is essential for changing environmental initiatives because purchasing is a key function for managing an upstream supply chain and to further achieve sustainability throughout the entire supply chain. Thus, this study was designed to identify important drivers of wine retailers' green purchasing by incorporating both individual factors (values and competences) and organizational culture. Hierarchical linear modeling was employed to analyze the nested data obtained from 457 purchasing managers working for 10 wine retail companies in the United States. Results documented that individual values (social desire and moral attitudes), cognitive competence, and organizational culture such as the ethical behavior of top management, positively and directly influenced wine retailers' green purchasing behavior. In addition, the study findings revealed that the effects of individual values and cognitive competence on wine retailers' green purchasing behavior were positively enhanced when organizational culture was formed based on top management's ethical behavior, codes of conduct and incentives. Implications for developing effective methods for improving wine retailers' green purchasing behavior are presented and discussed.


This article explains how the social documentary can function as a tool of denunciation and symbolic reparation as well as a vehicle for the empowerment of victims. Esperanza Huayama, vice president of the Asociacion de Mujeres Afectadas por las Esterilizaciones Forzadas (AMAEF) and leader of the Asociacion de Mujeres Campesinas de la Provincia de Huancabamba (AMBHA), is one of the most emblematic cases of forced sterilization in the province of Huancabamba, Peru. In the documentary Una voz esteril (2012), which I did as part of my doctoral research, Esperanza Huayama gives her testimony for the first time. Today she participates actively in protest marches in Lima and in meetings with parliamentarians, gives interviews to different public and independent media and interviews with the judges who have taken the case. She has travelled to Spain and England bringing the voice of the sterilized women of the country and feels responsible for representing them. She is aware of the impact this campaign has made on the media and the fact that she has become a public figure through the power of social networks and the denunciation documentary. Her case —and those of the women who make up the Instituto de Apoyo al Movimiento de las Mujeres (IAMAMC) and the AMBHA— provided me with evidence of how the case of sterilizations is remembered and how the citizens of Lima maintain a hegemonic and racist social discourse which allows them to ignore the rights of the populations affected by these policies.


Dear Editor-in-ChiefSeveral scholars pointed out the relationship between the function of muscle and teeth (1). The effects of breathing on facial growth and occlusion of the bite have been identified in various papers (2, 3). A breathing disorder occurs after upper airway blockage during sleep, it has not only nighttime symptoms such as snoring or apnea but also daytime symptoms such as behavioral disorder, excessive daytime sleepiness, concentration issue, memory, and cognitive function. Sleep is a physiological phenomenon essential for performing basic human functions and is important for normal growth and development, and for maintaining emotional health and immunity. Among various sleep disorders, Obstructive Sleep Apnea Syndrome (OSAS) is a common medical problem for children (4). Among the sleep disorders, obstructive sleep apnea has been reported in Korean children and adolescents based on polysomnography, relative to other sleep disorders. Sleep-disordered breathing can be prevented myofunctional therapy, the neuromuscular toning and re-education of oral, facial, and pharyngeal muscles (lips, tongue, cheeks, face, and throat) through a series of activities which helps normalize the developing or developed, head and neck structures and function, with orthodontic treatment (5,6). A recent research literature review shows myofunctional therapy for those whose tongues block their airway during sleep can reduce these choking events by approximately 50% in adults and 62% in children and those lowest blood oxygen saturations, snoring, and sleepiness outcomes improve in adults (7).We now have the evidence-based studies to validate the success of treating patients collaboratively with a variety of disorders (e.g., orthodontic disorders, sleep apnea, orofacial pain) but, until recently, there were not enough studies using oral appliance and myofunctional therapy of Korean children and adolescents. Since cephalometric radiography was introduced by Broadbent to evaluate the craniofacial morphology, as recently reported (8), to evaluate the size of the airways and tongue in patients with sleep apnea, it is widely used, but, not be evaluated in three dimensions.Cone-beam computed tomography (CBCT) is a useful nondestructive method for 3D reconstruction that can be used to visualize and measure the morphological structures of hard and soft tissue on face. 3D models reconstructed from CBCT and tomographic images can display the precise anatomical structure of Oropharyngeal space. In addition, CBCT is useful for establishing realtime clinical diagnoses of patients and treatment plans (9). Programs that accurately measure complex structures of 3D models mathematically are available, but no studies have attempted to measure the Oropharyngeal space area using CBCT technology. So, our study was conducted to evaluate three dimensional changes after Myobrace (Myofunctional Research Co, Australia) appliance treatment for the children with OSAS symptoms (Fig. 1, 2). Our study confirmed the increase of oropharyneal airway dimension using Myobrace (Fig. 3). We excluded the sleep symptoms of the participating patients.Although the majority of childhood obstructive sleep apnea is due to hypertrophy of adnexaadenoid, there is no correlation between the magnitude of hypertrophy and the severity of obstructive sleep apnea syndrome. …


Recently, scholars have begun to conceptualize oppressive experiences as traumatic events and have advocated that categories of traumatic events be expanded to include experiences of oppression that do not meet the traditional diagnostic criteria for posttraumatic stress disorder (PTSD). Building on this literature, this study explored the relationship between two kinds of heterosexist experiences, one that meets the traditional diagnostic criteria for PTSD (i.e., heterosexist hate crime victimization) and one that does not (i.e., heterosexist discrimination) and lesbians' PTSD symptoms. Furthermore, it explored the potential moderating and mediating role of self-esteem in the heterosexism-PTSD symptom link. Results revealed that both heterosexist hate crime victimization and heterosexist discrimination were unique and significant positive predictors of lesbians' PTSD symptoms. Support was found for a partially mediating but not a moderating role of self-esteem in the relationship between heterosexist discrimination and lesbians' PTSD symptoms.


In consistently expanding region and construction of present-day Power System having trouble request vulnerabilities, the utilization of learned and lively recurrence power technique is fundamental for good working of Power-station. To enhanced regulator boundaries, a SCiWOA has been utilized. Frequency soundness and control are perhaps the main issues in interconnected force matrices plan and operation. Several control circles are working to keep up with the framework recurrence at its set points. The majority of supply request adjusting is accomplished by controlling the yield of dispatchable creating units. Next viable utilization of Power-framework recurrence control is performed by planning a CFPID regulator for a brilliant matrix framework having limitless sources like sun situated, wind & photo-voltaic. All in all, to evaluate the framework performance, the time-domain simulations of different cases are considered.


Part of the controversy about allowing examinees to review and change answers to previous items on computerized adaptive tests (CATs) centers on a strategy for obtaining positively biased ability estimates attributed to Wainer (1993) in which examinees intentionally answer items incorrectly before review and to the best of their abilities upon review. Our results, based on both simulated and live testing data, showed that there were instances in which the Wainer strategy yielded inflated ability estimates as well as instances in which it yielded deflated ability estimates. The success of the strategy in inflating ability estimates depended on the ability estimation method used (maximum likelihood versus Bayesian), the examinee's true ability level, the standard error of the ability estimate, the examinee's ability to implement the strategy, and the type of decision made from the ability estimate. We discuss approaches to dealing with the Wainer strategy in operational CAT settings. The terms "review" and "item review" in testing contexts refer to administrative rules that allow examinees to change their responses to previously answered items. Review is a non-controversial element of most fixed-item, paper-and-pencil administered tests. Over a half century of research on review supports several conclusions: (a) only a very small percentage of answers are changed; (b) more answers are changed from wrong to right than from right to wrong (or wrong to wrong),


An analysis of the extensive experimental data of Frankenburg on the adsorption of hydrogen by metallic tungsten powder between −194 and 750°C has been made, using the Fowler‐Guggenheim treatment of adsorption phenomena as the mode of approach. It has not been found possible to interpret the data in terms of interaction between the adsorbed species on a uniform adsorbent surface. It is shown that the experimental data can be interpreted on the basis of a non‐uniform surface without interaction, the heterogeneity of the surface being specified in terms of an exponential distribution of sites given by the distribution function N=ce−χ/χm, where χ represents the energy difference between the lowest energy state of the gas and the lowest energy of the adsorption complex. Such a distribution function yields the experimentally observed relation d lnp/d lnθ=constant at constant temperature. Such a heterogeneity is especially significant in the case of tungsten metal which hitherto has been treated as an essential...


An abrupt interruption of the brain's blood supply leads to stroke, which causes severe damage to the brain. Due to this condition, there are people disabled and thus leading to death. In this work, the dataset contains ten features where environmental tests are done for the stroke which is utilized to evaluate the efficiency of Machine Learning classifiers and Deep Learning Artificial Neural Network. The purpose of this paper is to provide a forecast of the likelihood of a brain stroke occurring at an early stage using Machine Learning and Deep Learning techniques. The accuracy and efficiency of various types of Machine Learning models and customized Deep Learning models have been compared based on this impression. The custom Deep Learning model here used is an Artificial Neural Network with dropouts having the highest accuracy of 97.06% using RMSprop optimizer and a Decision Tree Machine Learning Classifier, achieved the highest accuracy of 95.98%.


Physical demo plays an irreplacable prole im Physics Teaching. But currently, there are many adverse problems in demo experiment. This paper tried to analyze the cause of these problems, and find out the method of putting the axe in the helve solutions


Pisang Island is one of the islands located in the Coastal West Lampung regency precisely in West Lampung. Expected with the development of Pisang Island as a tourist destination it will beable to increase revenue and the welfare of society in western Lampung. Utilization of coastal and marine resources in West Lampung could be the development of nautical tourism in the region in this regard Pisang Island. One form of nautical tourism is snorkeling and diving activities. However, in the tourist development efforts in Pisang Island have held identification and approach problems first. The most fundamental and the purpose of this studyis to conducta study on the suitability of water level in Pisang Island, especially for snorkeling and diving tourism activities. Research carried out by field observations (collecting primary data and secondary data) for 2 months in July 2011 to August 2011 in the northern part of the Pisang Island, which is divided into thirteen point sampling locations. Primary data collection consisted of coral cover data retrieval and type of life formusing LIT, count the number off is husing visual census of fish and measure the brightness levels use these cchidisk. The method used for the analysis of the research is descriptive method of analysis with the help of Travel Suitability Index which produces the suitability andvalue of the carrying capacity of tourist areas. Based on the results obtained from the calculation of travel suitability index for snorkeling and diving touris snorkeling tours there instations 1, 2, 3, and 5 are located at a depth of 3 meters. And for diving there instations 6, 7, 8, 9, 11, 12, 13 and 14 are located at a depth of 5 meter still 10 meters.


Understanding spatial and temporal variability of dissolved nitrous oxide (N 2 O) is essential to process understanding of N 2 O emissions from near-surface groundwater to the unsaturated zone and to the atmosphere. We propose a conceptual model of bubble-mediated mass transfer within the exchange zone defined by the range of groundwater fluctuations. Based on this model, we discuss our experimental data collected over a period of 2 years from of a small-scale test site (6.5 m x 2.5 m x 5 m, 20 observation wells), where we measured the dissolved gases N 2 O and O 2 at five different depths ( 0.1, 0.5, 0.8, 1.5, and 2.5 m below groundwater level). We show by visualization of the spatially interpolated data and by descriptive statistics that the N 2 O concentration of near-surface groundwater exhibits a significant anticorrelation to O 2 concentration, a spatial coefficient of variation up to 260%, and a spatial-correlation range at the meter-scale. The temporal variation of the spatially averaged data is correlated to the temporal variation of the averaged groundwater level. The implications of high spatial and temporal variability on gradient-based flux models like the steady state-flat interface model usually used in literature are discussed. Our main conclusion is that both the steady-state assumption and the flat-interface model are far from being realistic, because of (1) the highly transient behavior of the exchange zone and (2) the oversimplification of the gas-water interface that underestimates mass transfer by order of magnitudes compared to bubble-mediated mass transfer.


Based on the Γ-convergence theory and the properties of the almost periodicfunctions, we obtain an expression of the Γ-limits of a class of functionals, which unifies andsimplifies all the known formulae.


One of the most important questions of physics teaching is to introduce students to the creative way of problem-solving and to help them from novice to expert type thinking. The development of this capability can be effectively facilitated by producing various solutions to the same problem. This paper shows in a didactic way how one can build the equations of motions of increasingly intricate systems by the use of various theoretical models. Starting with the simple spring pendulum step by step the damped and forced spring pendulum is reached. We are using more ways to find the equations of motion (Newton's second law in inertial and noninertial systems, Lagrange method).


This paper mainly explored the contents and historical background of constructing the ecological and cultural villages accoreling to the developing reguirements of constructing socialist harmonious new countryside.Meantime,it explained further contents and principal of constructing the ecological and cultural villages on the basis of Chizhou City's reality or present situation in Anhui Province,and put forward the practical patterns and main measures about how to develop ment and construction of the ecological and cultural villages in Chizhou.


Aim. To investigate the association between daily physical activity and metabolic risk factors in Japanese adults with prediabetes or untreated early type 2 diabetes (T2D). Methods. Daily physical activity level was measured using a triaxial accelerometer. We assessed correlations between physical activity level and waist circumference, blood pressure, fasting levels of plasma glucose, serum triglycerides, and insulin and homeostasis model assessment-insulin resistance (HOMA-IR). Results. A total of 80 patients were studied. After adjustment for age and body mass index, in all subjects, physical activity level was negatively associated with waist circumference (β = −0.124, P = 0.018) and fasting serum triglycerides (β = −0.239, P = 0.035), insulin (β = −0.224, P = 0.022). In men, physical activity level was negatively associated with systolic blood pressure (β = −0.351, P = 0.044), fasting plasma glucose (β = −0.369, P = 0.025) and insulin (β = −0.362, P = 0.012), and HOMA-IR (β = −0.371, P = 0.011). No significant associations were found between physical activity level and metabolic risk factors in women. Conclusion. Objectively measured daily physical activity is beneficially associated with waist circumference, serum triglycerides, and insulin resistance in individuals with prediabetes or untreated early T2D. (This trial is registered with UMIN000015774.)


On the basis of systemic sample collection,by analyzing macerals,micro-fracture,facies,quality and mercury injection test on coal samples,the authors systematically studied the physical characteristics of Jurassic coal bed methane reservoirs in western Ordos basin.And the favorable area was calculated using multi-level fuzzy evaluation method.The results show that the Jurassic coal bed methane(CBM) reservoir in western Ordos basin has great gas potential,and its pore system has bimodal distribution,and is dominated by micropores,mini pores and macropores.The Erdaoling-Rujigou region is considered as the most favorable target area for CBM development.


Utilizing the critical theory of Drucilla Cornell and Costas Douzinas, and looking back to the utopianism of Ernst Bloch, the paperI offers an argument that acknowledges the limits of the law and the transcendent nature of justice with specific reference to the role of the Constitutional Court in South Africa.