Motor-driven equipment (ME) is one of the key components in an air-conditioning system, which contributes to the vast majority of the total energy consumption by air-conditioning systems. Distinguishing variable- and constant-speed equipment is important since the energy simulation models of the two types differ. Traditionally, types of ME are known in advance, and energy consumption data are consequently analyzed. However, in the application scenarios of energy consumption data mining, precedent information on the ME type could be missing. Thus, this study applies this process in reverse, providing new insight into energy consumption data of ME to recognize variable-speed ME in an air-conditioning system. The energy consumption data of ME in an air-conditioning system implemented in a commercial building were collected and numerically analyzed. A proposed simple parameter, coefficient of the median, and several numerical parameters were calculated and used to distinguish variable- from constant-speed ME. Results showed that the energy consumption data distributions of the two types of ME differed. The proposed coefficient of the median could successfully distinguish variable- from constant-speed ME, and it could be applied as an important step in energy consumption data mining of air-conditioning systems.


The theatre "Teatro di San Carlo" in Naples, built in 1737, is the oldest opera house still active in Europe. After a devastating fire in 1816, the theatre has been rebuilt and is being considered, until today, one of the most beautiful semi-classical opera houses in the world. Also, from the acoustic point of view, it is reputed to be one of the best theatres in the world. These excellent characteristics had to be maintained and in no way affected by the extensive restoration and extension works which were carried out during a period of one year and a half, until January 2010. On the contrary, if possible, the acoustics were even to be improved. The restoration of the auditorium in terms of room acoustics, the creation of new rooms above and under the auditorium as well as the installation of an air-conditioning system were, among others, the object of the acoustic project of Müller BBM. The activities carried out as well as the obtained acoustic results are being illustrated in form of objective measurements and subjective comments of the artists and the opera lovers.


In this paper the novel teleoperation method "Hands-Free" is presented. Hands-Free is a vision-based augmented reality system that allows users to teleoperate a robot end-effector with their hands in real time. The system leverages OpenPose neural network to detect the human operator hand in a given workspace, achieving an average inference time of 0.15 s. The user index position is extracted from the image and converted in real world coordinates to move the robot end-effector in a different workspace.The user hand skeleton is visualized in real-time moving in the actual robot workspace, allowing the user to teleoperate the robot intuitively, regardless of the differences between the user workspace and the robot workspace.Since a set of calibration procedures is involved to convert the index position to the robot end-effector position, we designed three experiments to determine the different errors introduced by conversion. A detailed explanation of the mathematical principles adopted in this work is provided in the paper.Finally, the proposed system has been developed using ROS and is publicly available at the following GitHub repository: https://github.com/Krissy93/hands-free-project.


BACKGROUND
The most important factor affecting metabolic excretion of compounds from the body is their half-life time. This provides an indication of compound stability of, for example, drug molecules. We report on our efforts to develop QSAR models for metabolic stability of compounds, based on in vitro half-life assay data measured in human liver microsomes.

METHOD
A variety of QSAR models generated using different statistical methods and descriptor sets implemented in both open-source and commercial programs (KNIME, GUSAR and StarDrop) were analyzed. The models obtained were compared using four different external validation sets from public and commercial data sources, including two smaller sets of in vivo half-life data in humans.

CONCLUSION
In many cases, the accuracy of prediction achieved on one external test set did not correspond to the results achieved with another test set. The most predictive models were used for predicting the metabolic stability of compounds from the open NCI database, the results of which are publicly available on the NCI/CADD Group web server ( http://cactus.nci.nih.gov ).


In 2004 RMIT was a recipient of a Hewlett-Packard Mobile Technology for Teaching Grant Initiative comprising equipment and a small development fund. RMIT selected a combination of 23 Tablet PCs and 50 iPAQ PDAs to conduct trials associated with two sub-projects to investigate the application of mobile technology in higher education. Students in the second year of a multi-disciplinary Bachelor of Design program used the Tablet PCs to facilitate the design process. The study used qualitative ethnographic methods to explore the impact access to mobile computing had on student learning and everyday work practices. These students used design applications in concert with web logging and other communication tools to support individual and group design projects across the full academic year. The design students used their Tablet PCs for wireless access, as well as in standalone operation and in some cases wired access. It was found that mobile computing had a substantial impact on their everyday work practices. Second year students in a Bachelor of Nursing program used the iPAQs to access standard applications as well as specialist pharmacological databases. The nursing students used the iPAQs primarily in standalone mode whilst on clinical placements. Both trials used qualitative methods to assess the impact of the new technology on the student experience. The nursing trial also used quantitative methods in a quasi-experimental design to assess changes in pharmacological knowledge. The results showed there was a modest improvement in both groups of nursing students on the post-test assessment. Students using the PDAs increased their mean score by 1.3 marks, and although this was not statistically significant, it was double the increase in the mean score of the comparative group. Overall students reported positively on their experience using mobile technology. The technology improved the efficiency of their study time, and improved their overall learning experience, although no definitive conclusions can be drawn about any improvement in learning. Students also had little difficulty in using the technology. From a university perspective, the trials indicated that wider adoption of mobile technology could be supported, but it may create a load on support and systems, and require more seamless integration of wired and wireless technologies. The experience gained from this project is broadly relevant to all science and engineering disciplines.


This chapter takes a closer look at linguistic and cultural features in a printed Judeo-Arabic version of the Joseph story, qiṣṣat Yosef ha-ṣadiq - ʿalav ha-salom , published in Baghdad in 1924. Of special interest in this text are traces of the Iraqi Arabic dialect landscape, especially traces of the communal dialects in Baghdad (Blanc 1964), in addition to the expected general features of Middle Arabic (MA) that one expects to find in this text genre. This popular version of the Joseph story is especially interesting against the canvas of Saʿadya Gaon's Judeo-Arabic translation of Genesis, as edited in Joshua Blau's chrestomathy of religious and scientific Judeo- Arabic texts. Author concentrates on some noteworthy phonological, morphological, syntactical, and lexical features of the text. Keywords: ʿalav ha-salom ; cultural features; Genesis; Iraqi; Joshua Blau; Judeo-Arabic text; linguistic; QiṢaṢ Al-ʾAnbiyāʾ ; qiṣṣat Yosef ha-ṣadiq ; Saʿadya Gaon


A magnetically-saturated controllable reactor based static VAR compensator(MCSR-SVC) was introduced.In a MCSR-SVC,the controlled voltage of the valve body is less than 10% of rated work voltage,so the purpose can be realized that high power is controlled by low power and only requires low-power thyristors in the HV network.In a single-generator infinite system,the one-order inertia model of the MCSR-SVC was derived with the small-disturbance method.The theoretical analysis indicates that MCSR-SVCs,compared with other SVCs,such as TCRs and TSCs,can compensate the reactive power more rapidly and accurately with little harmonics.Therefore it can stabilize the system voltage efficiently.The digital simulation results of open-loop and closed-loop responses of MCSR-SVCs prove the validity of the analysis.


A soil gas sample obtained by mass flow of gases may not be representative of the point sampled because of mixing with gases from other soil depths or from the atmosphere. The authors have investigated a method which eliminates this error and which is based on the diffusion of gases between a point in the soil to a collection chamber via a tube tightly fitted in the soil. A physical analysis and laboratory tests were made to determine the time required for the collected gas to be representative of the soil atmosphere at any depth. For all conditions, this time depends on initial differences between the partial pressure of a gas in the collection chamber and in the soil. When the percentage of water-free pores in soil is approximately 20 or greater, the time is strongly dependent on the volume of the collection chamber and on the diameter and length of the tube connecting the chamber to a point in the soil. For porosities between 0–15%, the effect of reduced diffusion rates in soil becomes significant and increases the time. Equations are given for making these calculations. An evaluation was also made of the condition in which (1) approximate equilibrium had been previously established between partial pressures in the chamber and in the soil, and (2) partial pressures in the soil were changing due to release or absorption of a gas. It was shown that the pressure of a gas in the chamber will not differ from its partial pressure in the soil by more than 0.5% unless concentration changes in the soil exceed 15% by volume per day. Oxygen analyses are shown for 2-years field results. The average coefficient of variation of oxygen concentration was a low value of 3% but was strongly dependent on soil moisture content. Some comparisons of soil oxygen concentrations obtained by pumping and by the diffusion-equilibrium method showed that the former method gave higher values.


The Internet has become an engine for growth and innovation and has been responsible for the heretofore unprecedented scale of sharing and access to information. However, today the Internet is also used for the illegal exchange of copyrighted materials. The fast changing nature of the Internet meant that the traditional copyright law was ill-equipped to handle this infringement. The Digital Millennium Copyright Act was introduced as an attempt to address the changing needs of the copyright law. One of the salient additions of the law was an extra-judicial mechanism to remove allegedly infringing content. This thesis examines the takedown process in practice in a structured fashion. As part of this work, we analyze the takedown notices made available to the public, in particular the Chilling Effects repository. We also run active measurement studies to understand the actions and reactions of the system as a whole. In addition to this, we address questions about the DMCA Section 512 process and the entities involved in this process. Finally, we also make specific observations and recommendations in an attempt to structure the future work in addition to summarizing the results of this work. In particular, we find that while the process is not able to take down all the infringing content, it is able to make it less accessible to a casual user


At the global level, the resources of oil and gas on the continental shelf have long been the main sources of increasing the level of hydrocarbon production. To date, the share of oil and gas produced on the continental shelf already exceeds 25 % of the global volume. The world's largest continental shelf is in our country: its oil and gas potential exceeds 30 % of all resources in the bowels of the shelf of the World Ocean. Over 85 % of the hydrocarbon resources of the Russian shelf are concentrated in the Arctic seas. This explains the relevance and necessity of scientific and technological progress in the development of the oil and gas industry of our country. The formation of an integrated transportation system for the development of hydrocarbon resources in the Far North is a complex technical task. It requires the development of existing and construction of new transport infrastructure elements: onshore and underwater pipelines of high length, storage and reloading terminals, oil and gas storage facili- ties, transport and auxiliary vessels, etc. Basic methods for transporting hydrocarbons from fields to treatment or storage sites, their advantages and disadvantages are analyzed. The most difficult question of developing offshore hydrocarbon resources in these seas is the choice of transportation schemes for severe climatic conditions, complex ice conditions, high distances from coastal regions and markets. Of particular importance in this situation is a preliminary analysis of available schemes and a choice of schemes for transporting hydrocarbons produced on the shelf, which will be the most economi- cally viable in each specific case.


ABSTRACTThe Aluminium foam is a new class of material with low density, better corrosion, wear resistance and low thermal expansion. Their applications are in lightweight structural components, sho...


mented the realities of life of those under thirty during the 1960s; it could be a skillful put-on. Read straight by a square, the two-hundred decibel noise level of the narration, the rock of continuous violence, and the rhythm of a not quite unbroken succession of campy pictures of a truly tragic assaults with fists, stones, clubs, bayonets, Gatling guns, and rifles convey the illusion of the Kent State murders taking place at three o'clock in the morning at the Fillmore East when that establishment was the national shrine of hysterical youth. Brecher advocates a world where the needs of the people are provided in a humane society made up of workers endowed with philosophers' wisdom and heroic capabilities. This utopian future will be ushered in by the "mass strike," which has been conceptualized by Rosa Luxemburg as climaxing a whole period of class struggle. "Its use, its effects, its reasons for coming about are in a constant state of flux... political and economic strikes, united and partial strikes, defensive strikes and combat strikes, general strikes of individual sections of industry and general strikes of entire cities, peaceful wage strikes and street battles, uprisings with barricades-all run together and run alongside each other, get in each other's way, overlap each other; a perpetually moving and changing sea of phenomena." In the context of this definition, with its emphasis on violence and lack of concern over issues, the author maintains that mass strikes include the Great Upheaval of 1877, the eight-hour day movement of 1886, the Pullman strike, the San Francisco waterfront strike and the textile strike of 1934, and the sitdown strikes of the late 1930s. Invariably in this reading, always slightly discordant with historical reality, an engulfing, fulfilling violence follows the strike. Noble workers of Galahad-like purity are striving to realize their revolutionary goals when union leaders or government officials intervene to frustrate a final victory. The sturdy toilers, however, will refuse wage increases or union recognition to insist on the establishment of rank-and-file control over the industry or the economy. Thus Brecher declares, recalling C. Wright Mills, that the CIO channeled the sitdown movement into organizational forms which, "far from challenging the power of the corporate rulers, actually reinforced their power over the workers themselves." Today's workers, undaunted by the oppressive weight of the capitalist superstructure, continue to conduct a secret struggle in the plants against their oppressors, by fighting incentive systems, fielding alternate systems of control, and mobilizing the rank-and-file into informal organizations which challenge all aspects of the establishment, including bosses, unions, and government. This is an engagingly romantic fantasy about the world, even if it is tarnished by a neurotic fixation on violence and is based on a perversely surrealist montage of data and make-believe (including references to Alfred Sloan on the purposes of the UAW, Root and Branch pamphlets, and assertions that all strikes are revolutionary). A kind of spuriously realistic fiction, with an unacknowledged source in Franz Fanon, Strike! is neither labor nor social history, nor serious political analysis. The total unreality of the descriptions of unions and informal organizations in the work place plus the compulsive evocation of murder and mayhem remind one of motion picture and TV westerns and crime melodramas which, like Strike!, are essentially combinations of mythology and violence. It is unfortunate that Brecher insists on perpetuating the false stereotypes of workers as thugs, ballbat wielders, mobsters, and criminals. These characterizations filled academic histories and texts in a time now past. They may serve the private fantasies of a few Rolling Stone readers, but the titillation is at the risk of grievous injury to the wageearners for whom Brecher pretends a romantic, reverential adulation.


Myocardial infarction (MI) is also called the heart attack, and it results in the death of heart muscle cells due to the lacking in the supply of oxygen and other nutrients. The early and accurate detection of MI using the 12-lead electrocardiogram (ECG) is helpful in the clinical standard for saving the lives of the patients suffering from this pathology. This paper proposes a novel approach for the detection of MI pathology using the multiresolution analysis of 12-lead ECG signals. The approach is based on the use of Fourier–Bessel series expansion-based empirical wavelet transform (FBSE-EWT) for the time-scale decomposition of 12-lead ECG signals. For each lead ECG signal, nine subband signals are evaluated using FBSE-EWT. The statistical features such as the kurtosis, the skewness, and the entropy are evaluated from the subband signals of each ECG lead. The deep neural network such as the deep layer least-square support-vector machine (DL-LSSVM) which is formulated using the hidden layers of sparse auto-encoders and the LSSVM is used for the detection of MI from the feature vector of 12-lead ECG. The experimental results demonstrate that the combination of FBSE-EWT-based entropy features and DL-LSSVM has the mean accuracy, the mean sensitivity, and the mean specificity values of 99.74%, 99.87%, and 99.60%, respectively, for the detection of MI. The accuracy value of the proposed method is improved by more than 3% as compared to the wavelet-based features for the detection of MI.


Traditional image retrieval systems consist of two working blocks for a query image: Feature extraction and similarity matching. This structure, however, does not provide satisfactory retrieval performances for different image databases. Therefore, image retrieval systems based on users' relevance feedback have been developed. Since this structure assumes the relevance feedback, it cannot be applied to fully automated systems. It can also annoy the users who may be reluctant to repeat the querying process. Therefore, we propose a better automated image retrieval system, which adds a classifier to the traditional system for giving feed-forward information to maximize the average precision. It requires a pre-analysis of the given image database.
We find that every category of images has its own mode (a combination of color space, quantization method, and similarity measure) leading to a better average retrieval performance than other modes. That is, there is no single mode to maximize the average retrieval performance for every category of images. Given a database, our proposed system will improve the overall precision by selecting the best mode based on known statistics (average precision vs. recall for each category). The Lloyd-clustered Gauss mixtures are used in the classifier to provide the feed-forward category information and in the quantization of color images for histogram generation.
The proposed system improves the retrieval precision by about 2.8 percent over our previous best single mode retrieval system. The result is better than that of the famous color indexing of Swain and Ballard (91') by 9 percent for the generic color images used. The proposed system can improve the retrieval precision by up to 5.5 percent over the best single mode retrieval under our experimental setup, given a perfect classifier.


The basic elements of criminalistics description of illegal turn of disks for the laser systems, matrices and raw material for their production are selected. It is basis for the construction of method of investigation of crimes of this type.


Machine learning techniques have been widely used in methods of network user's abnormal behavior detection.With the development of network,traditional detection methods cannot detect abnormal behavior accurately and quickly for their shortcomings such as cannot deal with unbalanced training data,huge demand for training data's label and so on.So this paper proposes a detection method based on selective collaborative learning.It uses improved EasyEnsemble algorithm to generate balanced training data.To improve the accuracy and reduce the cost of training, this method uses mixed perturbation algorithm to construct differentiated member classifiers and uses selective collaborative learning method to train them.Finally this method builds ensemble classifier according member classifiers' accuracy.Experiments showed this method can quickly and accurately detect abnormal behavior while reducing the demand for labeled training data.


The paper discusses how logistics service providers are using terminals in their supply chains. It argues that an increasing 'terminalization' of supply chains is unfolding, whereby seaport and inland terminals are taking up a more active role in supply chains by increasingly confronting market players with operational considerations such as imposing berthing windows, dwell time charges, truck slots, all this to increase throughput, optimize terminal capacity and make the best use of available land. With the development of inland terminals, a new dimension is being added: logistics players are now making best use of the free time available in seaports terminals and inland terminals, thereby optimizing the terminal buffer function. As a result, transport terminals are achieving an additional level of integration within supply chains that goes beyond their conventional transshipment role. Given increasing levels of vertical integration in the market and an increasing pressure on port capacity, a further terminalization of supply chains is likely to occur, which will strengthen the active role of terminals in logistics.


Our results are based on measurements carried out in a residential house in suburban area of Zagreb town, as well as in a medium-size office building (seven stories, approx. 150 offices) in the Zagreb city center, during two moths (late August, September and early October 2003). The noise samples were collected in five whole-day (6 am – 10 pm) campaigns. Those five days were equally distributed over the two-month period. Noise was measured with the spectrum analyzer, built in the instrument Anritsu Site Master S114B, between the neutral (N) and protection (PEN) wire, so that virtually no 50 Hz voltage was present on the analyzer port. Anyways, we have provided a simple overvoltage protection for the instrument, in case a temporary network fault occurs. We have studied noise on N-PEN pair because there is a technically well grounded tendency that this wire-pair, and not the neutral-phase or phase-phase, should be utilized for PLC systems, [1]. Beside noise measurements, we also carried out simultaneous measurements of the actual office building electrical load, by periodically reading its meter. This was needed for the investigation of correlation properties between the electrical load and total noise power in the 10 to 30 MHz band. In all measurements we have recorded both noise samples from one analyzer scan (lasting about 5 seconds), thus obtaining "temporary" shots, and 5 minutes maximal values, using max-hold function of the instrument. We found 5 minutes maximums interesting because of rapid temporal fluctuations in noise power levels. Resolution bandwidth of the analyzer was 10 kHz. On all figures in this article we use noise power levels in dBm recorded by the instrument with that resolution.


Introduction: Obesity is a proven risk factor for knee osteoarthritis (KO). The majority of actual studies reveals the association of thrombophlebitis with KO mainly after knee arthroplasty, needing anticoagulant prophylaxis. The aim of this study was to determine the association of KO with obesity and thrombophlebitis in our rehabilitation clinic division. Material and Methods: We analysed in a descriptive study 112 patient diagnosed with KO admitted between January 2014 and December 2015; we evaluated all patients according range of motion (ROM), body mass index (BMI) quality of life (QoL), and the numeric difference between calves diameter and we made ANOVA to compare means. All patients benefited for a specific rehabilitation program; p= value under 0.05 was considered statistically significant. Results: Mean age 65.08 (SD= 10.6), min 41 max 96, male: 40,17% female: 59,82%. Among analysed patients shows that: 41 individuals (36.60%) had obesity, 17 patients (15.17 %) had thrombophlebitis and only 10 (8.92%) had both association. Most contributively for KO are ROM (97.14), than QoL (92.3) and age (65.8) p-value<0.001. Conclusions: The association of KO with obesity and thrombophlebitis is a condition which should be considered. Important predictor factors for KO are obviously articular mobility but as well patient's QoL which interfere with the functional prognostic and results of rehabilitation program.


Current plant diversity can influence exotic plant invasion, but it is unclear whether there is a legacy effect of plant diversity on exotic plant invasion. As plant diversity can affect soil microbial communities and physio-chemical properties, which may cascade to impact subsequent exotic plant growth, we hypothesize that the soil legacy effect of plant diversity can influence exotic plant invasion.

 We conducted a plant-soil feedback experiment. In the conditioning phase, we trained soils by monocultures of 12 plant species from three functional groups (four grasses, three legumes and five forbs) and mixtures of eight randomly selected species with all three functional groups from this 12-species pool. In the test phase, we grew the invasive plant Bidens pilosa with a co-occurring native grass (Arthraxon hispidus), with a co-occurring native forb (Pterocypsela indica) or with both in each type of the conditioned soils.

 The performance of B. pilosa relative to its native competitors varied depending on the functional type of both conditioning plant species in the conditioning phase and competing plant species in the test phase. Diversity of the conditioning plants did not influence the growth difference between B. pilosa and its native competitors. However, increasing diversity of the competing plant species reduced the performance of B. pilosa relative to its native competitors. Our results suggest that current plant diversity can reduce exotic plant invasion through increasing growth inequality between invasive and native plants, but the soil legacy effect of plant diversity may have little impact on exotic plant invasion.


The intellectual role still has a powerful calling because the sacred fire of mankind has not been vanished: the action of discussing problematic issues. In fact, there is a minimum of cognitive grade, included in the most degraded analysis. This particular wandering of the spirit, or the exercise of intellect, may be defined as every process which can be used to record a human experience. The best metaphor to characterize it could be a travel. Even there is no a spatial movement from a place to another, but there is an imaginary movement, in which the wiser, without moving of this place, constructs a space from a present situation. He travels in a land imagined by the concepts, the abstractions which make him transcend his specific conditions (Ortiz "Taquigrafiando lo social") (Taking the social in shorthand). This present article will be used as a pretext to think some of the paradoxes that show the intellectual task. We will expose below about the partial understanding of the cognizing subject and the social origin of cognition; then we will make some considerations with respect to the history and social production of the intellect; and, finally, we will refer to the language as a constructor of reality.


Over the last 20 years in Australia the attitude of Government to policy evaluation has changed dramatically. Ministers (and Treasury officials) are no longer content to rely on anecdotes from agency heads as evidence that their programs are working. Rigorous evaluation is usually required, especially if the program is controversial or expensive. This is an encouraging development because it provides greater assurance that taxpayer funds are being wisely spent. Many of those responsible for fashioning or implementing new policies, however, though experts in their own field, have only a limited understanding of the circumstances in which rigorous evaluation is possible.


In order to reduce steam leakage loss and increase unit safety and economic efficiency,it is necessary to reform the traditional gland seal using advanced steam sealing technology.The application of the Brandon steam seal on N600-16.67/538/538 steam turbine was introduced.The system pipeline was optimized.By comparison of the thermodynamic test result before reformation with that after reformation,it was found that adopting the Brandon steam seal can reduce the heat rate of turbine considerably and enhance the operation economic efficiency of the turbine.


Summary The effect of variation in food intake and of unilateral nephrectomy on cellular proliferation in the kidney has been measured in weanling rats by means of autoradiography following flash labeling with tritiated thymidine. Labeling was used as an index of the proportion of cells engaged in DNA synthesis and thus in active proliferation. The labeling index decreased markedly from 0.65% to 0.06% after 24 hours of fasting. Refeeding after a 20-hour fast resulted in increased labeling after a 16-hour interval with return to normal levels at 24 hours. The stimulus of unilateral nephrectomy, which causes an increase in labeling index to 1.9% in animals fed ad libitum, failed to increase the index above 0.1% in fasting animals or in animals given 6 gm of food/day following a 4-day fast. The results suggest that renal work load may be the major factor stimulating cellular proliferation in the kidney, since loss of renal mass caused by nephrectomy failed to cause cellular proliferation in animals deprived of high levels of new metabolic products by fasting.


In Aesch.  Agam . 512, an emendation by M. L. West is supported by a new consideration involving the idiom in which a deity is requested to be sated with former infliction of harm and adopt a more benign attitude.


We show that an integer $ n\in \mathbb{N}\cup \lbrace 0 \rbrace $ is the forcing linearity number of a coatomic module over an arbitrary commutative ring with identity if and only if $n\in \left\{ 0,1,2,\infty \right\} \cup \left\{ q+2\left\vert q\text{ is a prime power}\right. \right\} .$


Objective To examine the association of intron 4 polymorphism in endothelial nitric oxide synthase ( eNOS) gene with diabetic nephropathy and its distribution in different ethnic groups of Singapore. Methods 258 patients with diabetic duration longer than 10 years (150 Chinese, 71 Malay and 37 Indian) were selected from both inpatients and outpatients of National University Hospital. Polymorphism was identified by DNA extraction, PCR, Cloning and sequencing. Results All published studies identified that the 27bp repeat polymorphism in intron 4 was biallelic ( a and b alleles ). Our study found a third allele-allele c, with six 27bp repeats. It was also demonstrated that there was no significant difference in overall allele distribution among the three main ethnic groups and the intron 4 polymorphism didn't show any association with diabetic nephropathy. Conclusion The intron 4 polymorphism was triallelic. We failed to demonstrate any association between this polymorphism with diabetic nephropathy.


In a solid oxide fuel cell (SOFC) stack the fuel and the air have to be uniformly distributed to a system of parallel channels. This is a difficult task, particularly when the total pressure loss of the stack should be kept as low as possible. In this paper a simulation program is described treating the problem of branching channels with a particular view to fast convergence for application as a subroutine to the main SOFC code. The simulation is experimentally verified and then applied to a planar SOFC cell and stack as well. The calculations show that a mass flow variation by a factor of 3 to 4 occurs along the stack. The effect on the integral operation quantities, i.e.cell voltage and performance is smaller than 1%, the local temperatures, however, increase by 20 K. Additional results of a sensitivity study are presented, particularly the effect of the manifold size on the mass-flow distribution.


This study aims to conduct a contextual analysis of Public Service Advertisements from the Ministry of Education and Culture: OVERSEAS WORKER. The approach in this research is qualitative with content analysis method. The source of the data in this study is the Public Service Advertisement from the Ministry of Education and Culture: OVERSEAS WORKER which is uploaded through the YouTube channel of the Ministry of Education and Culture of the Republic of Indonesia. From this research, four data were found that can be analyzed by contextual discourse analysis, which are divided into the principle of personal interpretation, the principle of locational interpretation, the principle of temporal or situational interpretation, and the principle of analogy.


MTs Tahfidz Al Qur'an Darul Qutub el Gontori is an institution that implements Islamic Full Day School (IFDS) with the aim of improving student achievement. Therefore, researchers will observe whether there is an effect of IFDS on increasing student achievement. The type of research is quantitative research with associative approach, the total population is 77 students, and the sample is 29 students. data collection techniques using, questionnaire interviews and observation. The analysis using product moment correlation analysis aims to determine whether there is a relationship between the X (IFDS) and Y variables (student learning achievement), and how big the relationship is between the two. The results of this study are student achievement in the Islamic Full Day School (IFDS) program at MTs Tahfidz Al-Qur'an Pagar Alam City is included in the good category and there is an increase, with the Islamic Full Day School (IFDS) bestajar bepen students it is known that the value of r obtained is in the other table product moment (r count) with the number of subjects 29 columns N in the 5% significance column for db 27 N = in rtable or rt = 0.487 den = thus greater than rt 5% significance level of 0.381 and rt rt 1% significant level of 0.470.


Bacillus exist in the form of spores with the characteristics of resisting for high temperature,acid,alkali and extrusion.It plays an important role in improving growth performance,meat quality and immunologic function.The article summarized the role and mechanism of Bacillus.


Abstract Most of the literature on the effects of German works councils does not deal with the issue of potential endogeneity of works council existence. Exploiting exogenous variation in works council authority stemming from a 2001 reform of the German Works Constitution Act, I apply a regression difference-in-difference using establishment panel data. I find that increasing works council size and the introduction of one full-time councilor causally reduces the number of voluntary quits by about 30 %. This decline is driven entirely by collective voice effects and there is no evidence for monopoly effects in place. Similar to the findings of previous research, the effect is significant only in establishments which are subject to a collective agreement. The results suggest that the effectiveness of works councils either heavily relies on the support of unions, or that works councils mainly serve as a guardian of collective agreements.


The indoles present in urine and blood of a wide range of primates have been investigated. The differences found appear to be of taxonomic significance.


2,2-bibenzyl-1,3,5-trithiane was prepared in solvent ethanol absolute,1,3-diphenyl-2,2-dithiol and methyl aldehyde as raw materials using p-toluene sulfonic acid as catalyst,the yield of 2,2-bibenzyl-1,3,5-trithiane was 51.7%,The thermal properties of 2,2-bibenzyl-1,3,5-trithiane was studied by DSC and TG method from 100~350 ℃ in the static.Hearing rate wae 10 ℃/min in the experiments.The results shows that can be oxidized over 231 ℃ in air.Therefore,it should be preserved under 231 ℃.And it can be used for soup seasoning rather than for barbecue.


Background/Introduction: As natural disasters continue to cause human suffering and contribute to health inequalities, Mobile Health Units (MHU) provide medical aid to people deprived of health care. However, the service modality has received criticism related to logistical difficulties, irregular service provision, and adaptability. Although MHUs may be of value, there is a significant knowledge gap regarding their usefulness on addressing health needs in natural disasters. Objectives: To elucidate the use of MHUs in natural disasters in adherence to WHO Classification for Emergency Medical Teams. Method/Description: A scoping review was conducted following the framework by Arksey and O'Malley. Twenty-six bibliographic databases and websites were screened for white and grey literature published from 2000-2021 reporting on the use of MHUs in natural disasters. Results/Outcomes: Thirteen publications were included in the final analysis, highlighting seven themes: key characteristics, services, staff, benchmark indicator, operational availability, self-sufficiency, and pre-deployment preparedness. All documents described the mobile approach to increase access to health services in the absence of regular health care. MHUs were mostly reported to provide out-patient care with medical needs primarily related to non-communicable diseases. Basic trauma care was less reported on. The main challenges concerned transportation, coordination, and communication. Conclusion: Data on the use of MHUs in natural disasters are scarce with inconsistent reporting of key aspects. The literature adhered to previous research and WHO guidelines to some extent. Further research is deemed necessary to evaluate the interventions and outcomes of MHUs following natural disasters.


This research examines the relationship between direct foreign investment and political protest in developing countries. A cross-national design is employed to investigate how investments in manufacturing and in mining interact with a society's historical relationship to the world system, its contemporary relationship to the world system, its economic structures, and its rate of social change to affect protest. The results show that manufacturing investments in new states and that are from the former colonial overlord are associated with lower levels of protest, while mining investments from a single foreign national source and in societies with high income inequality and a strong local capital structure are related to more protest. In countries with a large working class, both manufacturing and mining investments are associated with higher levels of protest


iii For my family iv ACKNOWLEDGEMENTS First of all, I wish to express my sincere thanks to my advisor, Dr. John Copeland for his insight guidance, endless patience and support. Without his help, this research could not have been completed. I am indebted to him. Dr. Alessandro (Alex) Orso and Dr Raheem Beyah for their valuable times, professional suggestions and gracious services on my committee. Myounghwan Lee for their valuable time and friendship. My most special thanks go to my parents Jiarang Xuan, Xiuying Zhu, and my wife Hu Tu for their everlasting encouragement, support and love.


Starvation resistance (SR) is an important trait for survival of insects in the wild. We used recombinant inbred lines (RIL) to search for quantitative trait loci (QTL) in crosses between intercontinental inbred lines that were originally selected for heat-knockdown resistance. SR was measured as the time of survival under repeated events of starvation. SR was consistently higher in females than in males. Composite interval mapping identified one QTL region (cytological range 64D - 66E2) on the left arm of chromosome 3 in males, and no QTL was found in females. Many candidate genes that were identified in previous studies of QTL for stress resistance are included within this QTL region. The QTL-allele that decreased SR was found in the line originating from the colder population (Denmark). We discuss our results with regard to multiple candidate genes, non-colocalization with thermotolerance QTL, and possible geographical variation.


An introduction to photoresist materials is presented, followed by a discussion of current modelling practices, focusing on dissolution models. The need for physical understanding of dissolution mechanisms is motivated. The results of experimental work and simulations on four negative chemically-amplified photoresists with var ied crosslinker structure are detailed, revealing some drawbacks in current kinetic models and showing that crosslinker structure has little overall effect on dissolu tion characteristics. Recent advances and current research in describing polymer dissolution mechanisms are discussed, and a simple simulation program of chainscission is applied to find the molecular weight distribution of PMMA after elec tron-beam exposure. Finally, directions for future research are presented, suggest ing the design of some experiments and future simulation programs.


We read with interest the study by de la Torre et al. comparing survival time of Caucasian patients with hepatocellular carcinoma (HCC) and portal vein invasion (PVI) after radioembolization using yttrium-90 microspheres (n=26) or sorafenib therapy (n=47). Respective median survival time was 8.8 and 5.4 months (p=.047) after median follow-up of 6 months. Around the same time, Cho et al. reported similar median survival time for Asian patients with HCC and PVI who received radioembolization (n=32) or sorafenib (n=31) (13.8 vs 10.0 months, p=.22). These results were confirmed by propensity score analysis. We applaud those authors for examining the suitability of radioembolization for patients with HCC and PVI, who currently have few treatment options and face extremely poor prognosis. At the same time, we think that more detailed analysis is needed in order to identify the most appropriate patient subgroups who may benefit from radioembolization or sorafenib, especially in the light of strong evidence that hepatic resection can be safe and effective for certain patients with HCC and PVI. The studies by de la Torre et al. and Cho et al. did not perform subgroup analyses by PVI grade, even though the grades are associated with substantially different prognoses. A systematic review of studies involving 4389 patients with HCC and macrovascular invasion found that hepatic resection was associated with median overall survival of 50% at 1 year and 18% at 5 years. A Japanese nationwide survey of 6474 patients with HCC and PVI found hepatic resection to be associated with significantly longer median survival than other treatments (2.87 vs 1.10 years, p<.001), and the rate of postoperative 90-day mortality rate was only 3.7%. This finding was also supported by propensity score analysis. Hepatic resection survival benefit was observed regardless of patient age, HCC etiology, tumour markers or tumour number. This extensive evidence suggests that hepatic resection can be safe and effective in selected patients with PVI in the segmental or sectoral branches of the portal vein (Vp0-2). It is less clear, however, whether hepatic resection is justified in patients with PVI in the main trunk or portal bifurcation (Vp3-4). We agree with de la Torre et al. and Cho et al. that radioembolization can provide good survival in patients with HCC and PVI, but its safety and efficacy should be verified in different PVI grades. Clinicians should also consider hepatic resection as an option for selected patients with PVI limited to the first-order branch. Financial Support


In this paper we discuss the problem of finding the treewidth and pathwidth of permutation graphs. If G[7r] is a permutation graph with treewidth k, then we show that the pathwidth of G[7r] is at most 2k, and we give an algorithm which constructs a path-decomposition with width at most 2k in time O( nk). We assume that the permutation 7r is given. For permutation graphs of which the treewidth is bounded by some constant, this result, together with previous results ([9], [15]), shows that the treewidth and pathwidth can be computed in linear time.


Cohen-Sutherland clipping algorithm may produce the invalid intersection points, which will reduce the efficiency of the whole algorithm. To avoid the shortcoming, this paper has put forward an improved algorithm based on Cohen-Sutherland algorithm. Given a line segment, by the coordinate values of clipping window vertexes and the implicit equation of the line segment, the improved algorithm can rapidly judge which clipping window edge has real intersection point(s) with the line segment. Experiments show that the improved algorithm is more efficient than other improved Cohen-Sutherland algorithms in reference papers.


Circularly polarized electromagnetic waves have unique advantages in removing artifacts in millimeter-wave imaging technology. In order to improve the working efficiency and detection accuracy of Ka-band millimeter-wave imaging systems, a polarization-converted beam scanning reflectarray antenna is proposed in this paper. The array antenna consists of a double-layer microstrip patch unit and a corrugated horn feed. The arrangement of the units on the front adopts the multi-focus design idea to meet the larger beam scanning range. The simulation results show that at a typical frequency of 35 GHz, the antenna achieves a gain variation of less than 2.3 dB within scanning angle $\text{of}\pm 30^{\circ}$, the side lobe level of less than 18.6 dB, and the axial ratio of less than 1.3 dB. This performance index shows that the reflect array antenna can be applied in millimeter wave imaging system.


Background
As in many other countries in sub-Saharan Arica, a shortage of well-trained health workers is one of the biggest barriers to quality health-care services in Ghana. Human resources for health deficits must therefore be addressed by improving the effectiveness and performance of the existing and future health workers through improved retention, competence and productivity. This PhD project was carried out in the framework of PERFORM, a health human resource management intervention that aimed at improving the performance of health workers by strengthening District Health Management Teams (DHMTs). Attrition and retention, both important factors of performance, were the main focus of this thesis, which were analysed from the management as well as the health workforce perspective.

Methods
The studies for this thesis were carried out in three districts of the Eastern Region in Ghana by using a mixed-methods approach. Data were collected during three research visits between May 2012 and July 2014 covering 13 months in total. The first study was a qualitative study on DHMT efficiency, which aimed to identify factors resulting in inefficient district health management practices. The second study was an explorative study that investigated current DHMT time use practices by doing daily retrospective time use interviews with all 21 district health managers in the districts over a three-month study period. In order to explore health worker motivation and job satisfaction and their effects on turnover and to also identify how district health managers may improve health workforce retention, 256 clinical health workers from several staff categories (doctors, nursing professionals, allied health workers, and pharmacists) were interviewed for the third study by employing a cross-sectional study design. Given the design of this study with only one measurement in time, turnover intention was used as a proxy of turnover.

Results
Financial constraints, human resource shortages in the DHMTs, low control over financial and human resources, little authority over district activities, and inadequate managing skills regarding planning and time management were identified as key management problems. However, district health managers have higher authority to allocate resources in their districts and to influence certain human resource aspects relevant for staff retention, such as promotions and study leaves. Managers used most of their working time for data management (16.6%), attending workshops (12.3%), financial management (8.7%), training of staffs (7.1%), drug and supply management (5.0%), and travelling (9.6%), while at the same time neglecting other activities such as human resource management (1.3%) and the management of buildings and equipment (0.2%). Of the interviewed health workforce, 69% (95% CI: 63-75) reported to have turnover intentions. Motivation (OR=0.74, 95% CI: 0.60−0.92) and job satisfaction (OR=0.74, 95% CI: 0.57−0.96) were significantly associated with turnover intention and higher levels of both reduced the risk of health workers having this intention. The dimensions of motivation and job satisfaction significantly associated with turnover intention included career development (OR=0.56, 95% CI: 0.36−0.86), workload (OR=0.58, 95% CI: 0.34−0.99), management (OR=0.51. 95% CI: 0.30−0.84), organisational commitment (OR=0.36, 95% CI: 0.19−0.66), and burnout (OR=0.59, 95% CI: 0.39−0.91).

Conclusion
There is a shortage of essential DHMT staff, especially regarding drugs and supply management, administration, and human resources. Hence, most management activities in these areas are neglected, which are sources of health worker dissatisfaction. Financial shortages in the DHAs were identified as another major reason for several of the low job satisfaction outcomes, as they lead to the inability to provide financial incentives to health staff, do regular maintenance of buildings and equipment, and to equip health facilities with the necessary basic supplies. Although district health managers have low authority to solve district specific problems with regard to human resources, findings from PERFORM have shown that adequate human resource management practices have the potential to influence motivation and job satisfaction, which in turn will make health workers more likely to remain in their current positions, thereby improving retention.


In this paper, three new ultra wideband (UWB) communication systems with quadrature-phase shift keying (QPSK) impulse modulation are proposed. First, direct-sequence (DS) multiple-access scheme is applied. The second proposed system is based on time-hopping (TH) multiple-access scheme. The last proposed system applies TH multiple-access scheme with QPSK impulse modulation and pulse position modulation (PPM). The conventional UWB communications as TH scheme with PPM modulation and DS scheme with binary-phase shift keying (BPSK) are used to compare. The simulation results show that all proposed UWB communication systems can provide obviously better performances compared with the conventional TH-PPM and DS-BPSK UWB communication systems. The comparisons in aspects of transmission bit rate and the number of users are also investigated.


After the world witnessed groundbreaking early advances in assisted reproduction that utilized conventional in vitro fertilization in the human, more complex invasive techniques of oocyte and embry...


Conventional analysis of fluorescence recovery after photobleaching (FRAP) data for diffusion coefficient estimation typically involves fitting an analytical or numerical FRAP model to the recovery curve data using non‐linear least squares. Depending on the model, this can be time consuming, especially for batch analysis of large numbers of data sets and if multiple initial guesses for the parameter vector are used to ensure convergence. In this work, we develop a completely new approach, DeepFRAP, utilizing machine learning for parameter estimation in FRAP. From a numerical FRAP model developed in previous work, we generate a very large set of simulated recovery curve data with realistic noise levels. The data are used for training different deep neural network regression models for prediction of several parameters, most importantly the diffusion coefficient. The neural networks are extremely fast and can estimate the parameters orders of magnitude faster than least squares. The performance of the neural network estimation framework is compared to conventional least squares estimation on simulated data, and found to be strikingly similar. Also, a simple experimental validation is performed, demonstrating excellent agreement between the two methods. We make the data and code used publicly available to facilitate further development of machine learning‐based estimation in FRAP.


In this article, I read two of Eliza Haywood's popular amatory novels—Love in Excess (1719) and The Distressed Orphan; or, Love in a Mad-House (1726)—in the context of her philosophical poems in order to shed light on the ways in which Haywood re-scripts both conventional seduction narratives and patriarchy's master narrative. Haywood uses the trope of confinement to reconceptualize the power of language in relation to female desire. She grants epistemological authority to women's intellect and to passion, and she uses the novel genre to show that illegitimate, feminized passion is as legitimate a way to understand the world as is masculinized reason.


An experimental study using microalgae Scenedesmus sp. growth rates are conducted in varies of environmental conditions that aim to access the growth rates effects of microalgae Scenedesmus sp. tolerance and capability to sustain in different type of abiotic conditions. Synthetics aqueous of Basal Bold Medium (BBM) was used to cultivate in batch mode using reactor flask under different abiotic parameters such as pH, temperature, lux intensity and photo period with objective of assessing the microalgae Scenedesmus sp. growth rates. These conditions are chosen due to its influential key on microalgae growth metabolism and nature of environmental where microalgae utilization will took place. The initial concentrations of microalgae are kept constant at 1000cells/ml as the other environmental factors are varies based on the nature of selected wastewater and surrounding nature. The optimum growth rates and tolerance of Scenedesmus sp. subjected to abiotic conditions are pH 7 to pH8, temperature is 250C to 300C, photoperiod is 12/12 (Light/Dark)(hr) and lux intensity of 4000. Microalgae Scenedesmus sp. can easily grow and adapt well in nature conditions as the optimums are precisely close to nature conditions.


Despite recent major improvements of water vapour (wv) databases, the insufficient quality or consistency of the H2O spectroscopic parameters has been reported many times and line parameters are often manually adjusted to minimize residuals and improve the quality of the fits. Atmospheric observations allow assessing the quality of databases through their simulation using the different line parameters reported in those databases. This work presents four concrete examples of the spectroscopic problems and proposed improvements in various spectral regions.


The present work develops an outline for the reprocessed of used oil of motors of internal combustion, with the objective of recovering some of the main such properties as viscosity, density, inflammation point, for its employment in its original form or in other, making pass through a channel zeolita filtrate with different grains what will contribute to a better administration and reutilization from a dangerously noxious waste to the environment.
Keeping in mind and taking advantage of the experience obtained in other investigation works about the filtrate of oil intends the design of an outline of filtration of the oil that is good as method for their reprocessed. Also studying the effects of the oils used in the environment, as well as an economic appraisement of the feasibility of undertaking the new investment.


Introduction Mustard oil contains about 60% monounsaturated fatty acids of which 42% erucic acid and 12% oleic acid . Rapeseed oil can contain up to 45% erucic acid . four-to-one mixture of erucic acid and oleic acid constitutes Lorenzo's oil ; an experimental treatment for a rare neurobiology disorder adrenoleukodystrophy . It is an x-linked genetic disorder that leads to demyelination of the central nervous system and primary adrenal insufficiently. ALD is characterized by the accumulation of saturated very long chain fatty acids (VLCFA) specifically lignoceric (c24:0) and cerotic (c26:0) acids. Introducing large quantities of Lorenzo's oil in the diet of ALD boys lead to an increased binding of these fatty acids with the elongating enzymes. As a result of this process, the production of toxic saturated is curtailed while that of innocuous monounsaturated fatty acids is increased. Method: Literatures were reviewed from journals in sciencedirect, pubmed, google, from 1990-2011. Findings and results: Moser and colleagues had conducted a study on 89 patients with confirmed ALD. Before treatment with Lorenzo's oil, all patients had normal MRI and neurological results. Daily oral doses of Lorenzo's oil were given, and other dietary fat intake was limited. At follow-up 13 years later, they found an association between the change in plasma-VLCFA concentrations and the development of abnormal MRI or neurological signs. 66 patients (74%) had normal neurological and MRI results, 21 (24%) had abnormalities on MRI, and only ten (11%) had clinical signs of neurological abnormalities.[1] A 10 year study of 107 boys with ALD has shown that Lorenzo's oil has some value as a preventive treatment and has significant reductions in the levels of very long chain fatty acids (VLCFAs) that correlated with a reduced risk of developing neurological abnormalities".[2] Moser and colleagues recommend giving Lorenzo's oil to asymptomatic boys with ALD, who have normal MRI and who are younger than 8 years. Key words: ALD, mustard oil, rapeseed oil, Lorenzo's oil.


Filed experiments were carried out to investigate some different mechanization systems for producing bean crop in new reclaimed land under Egyptian conditions. Seed bed preparation was investigated using chisel plow, moldboard plow and land leveler. Planting was investigated using both seed drill and planter comparing with the manual method. Harvesting was investigated using both self-propelled harvester and rear mounted mower at different forward speeds and different moisture contents comparing with the manual method. The obtained data revealed that, mechanical planting using seed drill, mechanical harvesting using selfpropelled harvester are considered the proper systems for producing bean crop in new reclaimed land under Egyptian conditions. Sinus they recorded maximum productivity of 1.387 ton/fed and minimum cost unit of 48.3 L.E/ton. Seed moisture content of about 11.5 % and forward speed of 2.8 km/h are considered the proper conditions for harvesting bean crop as it recorded minimum seed losses of 3.41 %.


The Neu/HER‐2 receptor tyrosine kinase is overexpressed in some types of human adenocarcinomas, including tumors of the breast and the ovary. A 44 kDa glycoprotein that elevates tyrosine phosphorylation of Neu has been isolated and named Neu differentiation factor (NDF), or heregulin. Here we show that NDF affects tyrosine phosphorylation of Neu in human tumor cells of breast, colon and neuronal origin, but not in ovarian cells that overexpress the receptor. By using monoclonal antibodies (mAbs) to Neu, we found that the ovarian receptor is immunologically and biochemically similar to the mammary p185neu. Nevertheless, unlike breast‐derived Neu, the ovarian protein did not display covalent cross‐linking to radiolabeled NDF, and was devoid of ligand‐induced association with phosphatidylinositol 3′‐kinase. Direct binding analysis showed that NDF binds with high affinity (Kd approximately 10(−9) M) to mammary cells, but its weak association with ovarian cells is probably mediated by heparin‐like molecules. Similar to the endogenous receptor, the ectopically overexpressed Neu of mammary cells, but not of ovarian and fibroblastic cells, exhibited elevated levels of NDF‐induced phosphorylation and covalent cross‐linking of the radiolabeled factor. Taken together, our results imply that NDF binding to cells requires both Neu and an additional cellular component, whose identity is still unknown, but its tissue distribution is more restricted than the expression of the neu gene.


The invention discloses a method for reinforcing integral replacement concrete of a high-rising building steel bar concrete column, and aims to solve the problem that unqualified steel bar concrete frame column can not be effectively treated by the prior replacing concrete reinforcing method under a condition that the frame concrete columns endure huge load. The method comprises the following steps: mounting an unloading support on the beam end on the periphery of a replaced column; dividing the replaced column into a plurality of parts; manually removing concrete and mounting a profile steel support in sequence; welding a batten plate on the profile steel support to form a structural batten plate column; building concrete on the position of the original replaced column; and detaching the unloading support on the edge of the column. The method can perform integral replacement on the unqualified column of the high-rise building, has small economic loss without affecting the appearance and use functions of the building, need not stop construction for the upper building during construction, and can not cause adverse affect on commercial housing and disturb the selling of the commercial housing.


1017 Background: Dosage of chemotherapy based on body surface area (BSA) does not consider differences in drug clearance and sensitivity, which could result in over- or under-treatment. Several retrospective studies have demonstrated a worse outcome in patients not achieving leucopenia during adjuvant chemotherapy. The SBG 2000-1 trial is the first adjuvant randomized trial designed to compare individually dosed chemotherapy based on grade of leucopenia to standard dosed chemotherapy based on BSA only.

METHODS
Patients with early breast cancer were included and received the first cycle at a standard dose of FEC (fluorouracil 600 mg/m2, epirubicin 60 mg/m2, cyclophophamide 600 mg/m2). Patients with nadir leucopenia grade 0-2 after first cycle were randomized between either 6 tailored FEC with increased doses (E 75-90 mg/m2, C 900-1200 mg/m2) or continuos treatment with 6 standard FEC. Patients with nadir leucopenia grade 3-4 after the first cycle were not randomized but represented a second control group treated with 6 standard FEC. Primary end-point was distant disease-free survival (DDFS).

RESULTS
A total of 1,535 patients were included in the study. After cycle one 1052 patients with low toxicity (leucopenia grade 0-2) were randomized to tailored FEC (n=524) or standard FEC (n=528) whereas 401 patients with leucopenia grade 3-4 continued standard FEC and were registered. With a median follow-up of 5.5 years the 5-year DDFS was 85% and 84% (HR 0.80, CI 0.59-1.08, p=0.14) with a disease-free survival of 82% and 79% (HR 0.76, CI 0.58-0.99, p=0.04) for the tailored and standard FEC group respectively. The overall survival was 90% and 89% (HR 0.80, CI 0.56-1.13, p=0.20,). The 5-year DDFS for the registered second control group was 85% and did not differ from the group of patients allocated to tailored FEC (HR 0.94, CI 0.67-1.32).

CONCLUSIONS
The SBG 2000-1 study failed to show a statistically significant improvement of tailored dosed chemotherapy compared with standard BSA based chemotherapy. However, all efficacy parameters showed trends towards a better outcome for the tailored treatment with estimated hazard ratios of considerable magnitude.


Abstract In recent years, the University of Liverpool has undertaken extensive research and development on work‐based learning across a range of academic disciplines, notably with Departments heavily involved in training for the professions. This paper considers this work and finds strong parallels between the experience gained the findings of recent research at Liverpool on school‐ based teacher training. In particular, the paper considers one issue ‐‐ that of progression, focusing on the changing needs of learners when on extended work placement and identifying implications for mentors. The paper concludes that much can be learned by those responsible for teacher training from the experience gained in other professions.


The friction and wear properties and mechanical properties of bronze/PTFE filled with different content of nano-Al2O3 were studied.The worn surfaces of composites were investigated by SEM as well as the abrasion mechanism.The results showed that nano-Al2O3 and bronze exhibited good synergistic effects on the wear resistance of PTFE composites.The wear resistance of PTFE composites filled with nano-Al2O3 and bronze improved greatly but the tensile strength and elongation at break of composites decreased.The wear wide scar of composites filled with 40% bronze and 5% nano-Al2O3 decreased from 12.0 mm to 5.0 mm,and the volumetric wear rate decreased from 171.40×10-6 mm3/(N·m)to 12.11×10-6 mm3/(N·m).


Presents a comparison study of the well-conditioned workspace, stiffness and inertia properties of four 3 degree-of-freedom (DOF) translational parallel manipulators. The well-conditioned workspace of each architecture is maximized and plotted. The stiffness properties of these architectures are then determined. Finally, the inertia properties of these architectures are determined. The limb lengths are normalized to ensure a fair comparison. The results obtained provide a performance index for each of these architectures. The comparison study indicates that none of the architectures is superior to all others with respect to all performance measures. An architecture which suits certain specific performance requirements best should be chosen for an application. Hence this approach is expected to be useful for the conceptual design of hybrid kinematic machines.


Estimation of the cost of a construction project is an important task in the management of construction projects. The quality of construction management depends on accurate estimation of the construction cost. Highway construction costs are very noisy and the noise is the result of many unpredictable factors. In this paper, a regularization neural network is formulated and a neural network architecture is presented for estimation of the cost of construction projects. The model is applied to estimate the cost of reinforced-concrete pavements as an example. The new computational model is based on a solid mathematical foundation making the cost estimation consistently more reliable and predictable. Further, the result of estimation from the regularization neural network depends only on the training examples. It does not depend on the architecture of the neural network, the learning parameters, and the number of iterations required for training the system. Moreover, the problem of noise in the data is taken into account in a rational manner.


ABSTRACT This article analyses the transformation of Robert College, the first American college founded abroad, from 1923 to 1970. Based on a careful investigation of Robert College archives and personal accounts of the College staff, it contends that the school's missionary character acquired a new identity after the foundation of Republican Turkey. Robert College gradually abandoned its missionary tradition to become an institution of liberal learning in the service of westernizing Turkey. The College presidency and trustees have long elaborated on the new context and trends in liberal education in the United States. At the same time, the Turkish officers and graduates quickly adjusted to this new character immersed in secular values. The College's transition involved a shared commitment going beyond political partnership, reflecting an intellectual vision that came out of long years of negotiations within the College establishment.


The changes of social environment,the internal environment of school, and the rural secondary teacher self own point of view,are the key reasons for mental problems of rural secondary teacher,the changes of personnel training mode and teacher evaluation system,teacher self-adjustment,are the main strategies to solve the mental problems.Only all sectors of society work together can we help rural secondary school teachers completely solve the mental problems


Abstract The emission cross section for the 2 F 5/2 – 2 F 7/2 transition of Yb 3+ has been determined from absorption and emission measurements of some borate glasses at room temperature. By systematic variations in the spectroscopic properties with composition, a glass composition with emission cross sections of more than 1.70 pm 2 and fluorescence lifetimes longer than 1.0 ms is obtained; this composition has advantages over some excellent laser glasses reported in published papers.


In a process for detecting the intention of a driver to start a stationary motor vehicle, the variation in engine speed is monitored when the accelerator is actuated, i.e., when the fuel feed increases, and the intention to start is detected when these variations lie with a certain range.


Abstract Background: Anemia is a commonly encountered clinical problem in the critically ill. Ninety-five percent of critically ill patients who stay in the Intensive Care Unit (ICU) for 72 hours or greater suffer from anemia and approximately 40% of them receive Packed Red Blood Cell (PRBC) transfusions. In 2001, nearly 14 million units of packed red blood cells were transfused, but the physiologic basis for transfusion in the critically ill is not without controversy. In the last two decades transfusion practices have become more restrictive likely in response to prospective research. Aim of Study: The aim of this work is to evaluate the prevalence of anemia in critically ill patients and to assess the effect of anemia of critical illness on the patients' outcome. Patients and Methods: The study was conducted from the existing data base in the Critical Care Department of Elsahel Teaching Hospital from January 2015 to December 2018. The collected data focused on fulfilling the following measures on the selected patients: Comparison of age, length of ICU stays of the patients and APACHE II score in survivors and non survivors groups, frequency of blood transfusion and iron supplementation in the management of anemia of critical illness and its association with the outcome, the relation of follow-up complete blood count and the outcome. Results: In this retrospective cohort study involving 165 patients 74 males and 91 females with mean age 55. 13±20.72, and mean length of stay 11, 87±12,04. The survivors were 103 (62.5%), and those who not survive were 62 (37.5%) the mean hemoglobin at admission was 8.28g dl–1 (±1.96) for survivors group and 8.27 (±2.36) for non survivors. reasons of admission which were associated with higher frequency of mortality among the others are post cardiac arrest, respiratory failure, neurologic problems, cardiogenic shock, septic shock, acute renal failure and obstetrics catastrophes with frequency (85.7%, 77.8%, 66.7%, 60%, 55%, 45.5%, 60%) respectively. Regarding blood transfusion as in management of anemia, in this study there were no significant difference in relation of blood transfusion and the outcome (our hemoglobin threshold was 7g/dl). In this study we had 78 patients admitted for more than fourteen days in the ICU they represent 25% of our study group 39.7% of them died with hemoglobind 7g/dl which was chosen as a best predictor to outcome. Conclusion: It was found that there is no association between management of anemia (blood transfusion and iron supplementation) and the outcome of the patient and that patient's hemoglobin at the end of ICU stay is of good prog-nostic value of anemic patients.


[Objective]To study cracking walnut technique and improve whole kernel yield. [Method]With Xinjiang Wen 185 walnut as study object,the influences of moisture content of walnut,loading-rate and loading-position on the rate of whole kernel were investigated by quadratic regression rotary combination experiments. Excel and SAS software were used to analyze the experimental data. [Result] The results showed that,moisture content of walnut,loading-rate and loading-position had significant effects on the rate of whole kernel; The maximum rate of whole kernel with new technology is as high as 60. 28% when deformation amount was 12 mm,the moisture content of the walnut was 8%,loading-rate was 300. 15 mm /min and loading-position at"C". [Conclusion] The study and results can provide a theoretical basis for cracking walnut and fetching kernel of"Xinjiang Wen 185"walnut.


Otitis media (OM) has several forms and among the main are otitis media (AOM), OM with effusion and chronic otitis media (COM) (cholesteatomatous or not). For the most part, the OM progressed well, but there are risks of complications and sequelae. These are divided into extra and intracranial, the first being the most common, but less lethal. Among the extracranial are: labyrinthine fistula, subperiosteal abscess, mastoiditis, temporozigomatic abscess, Bezold's abscess, parapharyngeal abscess, facial palsy, petrositis and labyrinthitis. Among the intracranial are: meningitis, epidural abscess, subdural empyema, brain abscess, the sigmoid sinus thrombophlebitis and otological hydrocephalus. The aim of this study is to identify the main complications of otitis media, distinguishing them from the incidence, degree of morbidity and mortality and analyze the development, management and treatment required for each entity. Brain abscess is the most common entity and subperiosteal abscess is the most common extracranial complication. Labyrinthine fistula occurs most often related to OMC. This has the physiopathology erosion of the bone covering the semicircular canal, usually the lateral semicircular canal. Labyrinthitis results from the spread of infection from the cochlear window membrane and can be presented in two ways: serous or suppurative labyrinthitis. The most common intracranial complication is meningitis, rarely associated with cholesteatoma and most often associated with AOM, of higher incidence in children. CT with contrast is the gold standard when you suspect any complications in patients with otitis media after undergoing a thorough history and physical examination. When the physician knows the possible complications and their signs and symptoms, the diagnosis is early and the prognosis best. Treatment of complications in general is based on patient hospitalization, myringotomy with culture and sensitivity, intravenous antibiotic therapy as early as possible and mastoidectomy in all cases related to COM or recurrent complications.


The LMC method of construction which have application to the road bridge is being considered the least relative importance about the watertight performance, because it focused on the durability of concrete. However, The LMC which is being expanded scope of application to the method of construction has grown importance about the watertight performance on the usability and maintenance side as well as durability. In this study, The latex concrete of two types which are different from mingled-ratio of the latex made a comparison to the compressive strength, watertight performance, dynamic wheel load resistance performance and confirmed what it has resistibility about chemical action through the chemical resistance test. The initial strength and watertight performance showed that were tendency the downward at 14 days. However, The long-term strength after 28 days showed that it has firm performance. In consequence, The initial curing of latex concrete is required to scrupulous care and attention at the site application. As a chemical resistance test result, The specimen that is steeped in sulphuric acid solution of 2% discovered the delamination phenomenon. However, it was confirmed that delamination phenomenon don't have an effect on the compressive strength. Moreover, As a dynamic wheel load resistance test result, The latex concrete was concluded to confirming the durability and running stability, because it had hardly any thickness reduction of latex concrete surface about dynamic wheel load and rarely found crack and delamination.


Kinetic studies on photoinduced and thermal electron-transfer oxidation of a variety of organosilanes in acetonitrile at 298 K are reported in terms of the electron-transfer rate constants (k et ) with a series of oxidants having the known one-electron reduction potentials (E 0 red ). The Rehm-Weller Gibbs energy relationship is applied to determine the fundamental parameters for the electron-transfer oxidation, i.e., the one-electron oxidation potentials (E 0 ox ) and the intrinsic barrier for the electron-transfer oxidation (ΔG 0 )


Renal scintigraphy was performed to rule out a urinary leak on a 47-year-old woman a few days after she underwent pediatric cadaver kidney transplantation. Because of the chronic shortage of donor organs, paired pediatric kidneys (from donors younger than 5 years old) are increasingly transplanted using en bloc extraperitoneal anastomosis of the donor aorta and vena cava into the recipient's extemal iliac artery and vein. The transplantation of two infant kidneys into one recipient doubles the amount of functional renal mass and increases the chance of good long-term renal function. The postoperative scintigraphic evaluation did not show any abnormality.


The wavelengths used in PDT are in the red or infrared range of electromagnetic wave. For a photobiological reaction to occur light must be absorbed by the photosensitizer. This is possible when the wavelength of light matches the electron absorption spectrum of the photosensitizer (Hsi et al., 1999). For clinical use the activating light is usually between 600 and 900 nm. This is because endog-enous dyes, mainly hemoglobin, strongly absorb light below 600 nm and longer wavelengths are energetically insufficient to produce 1 O 2 , which is the most important although not the only cytotoxic ef-fector of PDT. A critical parameter for consideration in discussing the efficacy of PDT is the depth of light penetration through tissues, which is dependent Photodynamic therapy (PDT) is a clinically approved and rapidly developing cancer treatment regimen. It is a minimally invasive two-stage procedure that requires administration of a photo-sensitizing agent followed by illumination of the tumor with visible light usually generated by laser sources. A third component of PDT is molecular oxygen which is required for the most effective antitumor effects. In the presence of the laĴer, light of an appropriate wavelength excites the photosensitizer thereby producing cytotoxic intermediates that damage cellular structures. PDT has been approved in many countries for the treatment of lung, esophageal, bladder, skin and head and neck cancers. The antitumor effects of this treatment result from the combination of direct tumor cell photodamage, destruction of tumor vasculature and activation of an immune response. The mechanisms of the direct photodamage of tumor cells, the signaling pathways that lead to apoptosis or survival of sublethaly damaged cells, and potential novel strategies of improving the antitumor efficacy of PDT are discussed. Photodynamic therapy is a minimally inva-sive therapeutic modality approved for the treatment of neoplastic and vascular diseases. It consists of three elements: a photosensitizer that is applied topically or administered systemically; light usually in the visible range, commonly generated by laser sources, and molecular oxygen, which in the pho-todynamic reaction generates singlet oxygen (1 O 2) and reactive oxygen species. AĞer a period necessary for efficient accumulation of the photosensitiz-er in the tumor, a light of appropriate wavelength is precisely delivered to the target tissue. Since light used in PDT is of low power there is no tissue heating and connective tissues containing collagen and elastin fibers are not damaged. Excellent cosmetic results in the treatment of skin cancers …


Background: Patients' oral health is impaired in Intensive Care units (ICUs) due to loss of consciousness, open mouth, intubation, and mechanical ventilation. Objectives: The current study aimed to compare the effects of comprehensive and combined programs on oral health in patients under mechanical ventilation. Methods: This single-blind clinical trial with three groups was performed on 90 patients with mechanical ventilation admitted to ICUs of medical centers affiliated to the Zahedan University of Medical Sciences, Iran, in 2020. Patients under mechanical ventilation were randomly divided into three groups, including those receiving a comprehensive program, those receiving a combined program, and controls through permutated blocks. In the two intervention groups, oral care was performed for 5 minutes, three times per day, during the 5 days of the study with a specific method. The control group received routine oral care. The patients' oral health was measured once before the intervention and then every day until the fifth day of the intervention using the Beck Oral Assessment scale. The data were analyzed using the analysis of variance and chi-square in IBM SPSS Statistics software version 26. Results: The mean oral health score in the three groups was not significantly different before the intervention and on the second day of the study (P > 0.05). However, on the third to fifth days of the study, the oral health score in the two intervention groups showed a significant decrease compared to the control group, indicating an oral health improvement in these groups (P = 0.001). The mean oral health score in the control group increased during the study days. Conclusions: Comprehensive care and combination methods can improve oral health in patients under mechanical ventilation. Nurses are recommended to use regular and codified oral care methods.


The material distribution inside tree crowns is difficult to quantify even though it is an important variable in forest management and ecology. The vertical distribution of a relative density index (i.e., vertical profile) of the total, woody, and leafy material at the crown scale were estimated from terrestrial laser scanner (TLS) data on two species, sugar maple (Acer saccharum Marsh.) and balsam fir (Abies Balsamea Mill.). An algorithm based on a geometrical approach readily available in the Computree open source platform was used. Beta distributions were then fitted to the vertical profiles and compared to each other. Total and leafy profiles had similar shapes, while woody profiles were different. Thus, the total vertical distribution could be a good proxy for the leaf distribution in the crown. Sugar maple and balsam fir had top heavy and bottom heavy distributions respectively, which can be explained by their respective architectural development. Moreover, the foliage distribution of sugar maples shifted towards the crown base when it was found in mixed stands, when compared to pure stands. The opposite behavior was observed for balsam firs, but less pronounced. According to the shape of the foliage distribution, sugar maple takes advantages from mixture contrarily to balsam fir. From a methodological point of view, we proposed an original approach to separate wood from leaf returns in TLS data while taking into account occlusion. Wood and leaf separation and occlusion problems are two challenging issues for most TLS-based studies in forest ecology.


Abstract Spongicola tropicanus, a new genus and species of the family Eunicicolidae, and Asterocheres brevisurculus, a new species of the family Asterocheridae, are described as copepods associated with the sponge Phyllospongia foliascens (Pallas) from the Moluccas. Spongicola is the second genus of the family and may be characterized by a two‐segmented prosome, the absence of leg 3, and the presence of leg 5. Asterocheres brevisurculus may be charecterized by one‐segmented mandibular palp, short oral siphon, and 19‐segmented female antennule.


Now the demand for intelligent video processing is getting greater and greater, moving body behavior classification from video images is their focus and difficulty. An approach to extracting human body and classifying the behaviors of the moving objects is presented in this paper. A statistical Gaussian model is used as adaptive background updating method. After foreground objects are segmented from the video images, we propose a novel skeleton model of the foreground objects model for feature extraction. The angles that can represent the pose of the skeleton model and length-width ratio of the human are used as feature vector. Then Bayesian Networks is used as classifier for behavior classification. The experiments show good recognition rate for moving human behavior classification.


The Wiener index W (G) of a connected graph G is defined as the sum of distances between all pairs of vertices in G. In 1991, Šoltés [9] posed the problem of finding all graphs G such that equality W (G) = W (G − v) holds for all vertices v in G. The only known graph with this property is the cycle C11. Our main object of study is the relaxed version of this problem: find graphs for which Wiener index does not change when a particular vertex v is removed. This overview contains results which were obtained and published during the past two years concerning relaxed Šoltés's problem.


Teaching Sociology recently published several articles dealing with the use of computer-assisted pedagogical techniques. Many authors assess the effectiveness of specific computer-assisted instruction (CAI) forms by examining either student performance (Conklin 1976; Dietz 2002; Lavin 1980; Neapolitan 1989; Raymondo and Garrett 1998) or student course evaluation (Ammarell 2000; Fuller 1998; Hare 1999; Persell 1992; Valentine 2001). Some studies look at both (Dimitrova, Persell, and Maisel 1993; Fischer 1996; Magnuson-Martinson 1995; Pippert and Moore 1999; ReedSanders and Liebowitz 1991; Wilmoth and Wybraniec 1998). Most of these projects compare groups of students, such as course sections, within a specific course. Typically one group uses some form of CAI while the other does not. By not comparing these pedagogical techniques between different courses, previous studies do not focus on the types of courses where the use of CAI is more or less effective. This case study examines two different lecture-based courses comparing the use of a traditional, "chalk and talk" pedagogy with an approach complementing lecture


General situations of Gongtan town in Youyang county of Chongqing are introduced.as well as historical evolution and form transition.From three aspects: land use situations,street texture and architecture the characteristic style of Gongtan town is introduced.The ideas and key points of its relocation are discussed;at the same time general scheme concept is proposed in order to realize protection and renewing of traditional characteristic style regions.


The article investigates the distribution and access to vacancies in municipal schools in Rio de Janeiro, focused on school availability. It summarizes a bibliography about enrollment/choice rules in school networks in different countries. The analysis is centered on two heterogeneous enrollment poles with a large flow of students between the first and second divisions of elementary school. The analyses illustrate the flow pattern among schools and identify the procedures and justifications used by school administrations in the selection and distribution of students. The results show non-random patterns of student distribution and the occurrence of veiled actions of the actors who reveal loopholes in the registration rules and contribute to school segregation in the city.


The pore size of membrane filter used in the filtering of photoresist for ULSI manufacturing is now shifting from 200 nm to 100 nm, but the photoresist end-users are asking for a much finer filter pore size. By knowing the size of its polymer it is possible to know the limit of the pore size required to filter the photoresist. From the results of ultra filtration and measurement of light scattering of the photoresist, the limitation of the filter pore size for the photoresist filtration and the detectable particle size in the photoresist were determined. In the ultra filtration of OFPR-800 (positive photoresist of Tokyo Ohka Kogyo Co., Ltd.) molecules larger than 13.5 nm in the original solution have been removed using a 13.5 nm filter. The maximum particle size of OFPR-800 novolak resin molecules measured by dynamic light scattering spectrophotometer was 32 nm and the average particle size was 5.4 nm. Furthermore, particles were observed larger than 32 nm. Because a positive photoresist is a highly concentrated polymer solution of 20 - 30 wt% it has been determined that those particles larger than 32 nm are large polymer groups similar to macro-molecules resulting from the intertwisting of novolak resin. It has been determined that the limit of the filter pore size that can filter a positive photoresist is 50 nm and the detectable particle size is 100 nm.


This work demonstrates a wind power system design for water pumping applications in isolated and remote areas. The proposed design involves wind turbines, asynchronous generator, three-phase AC to DC rectifier (power circuit part), voltage regulator (power circuit part), and DC motors that drive centrifugal pumps. The used AC to DC rectifier is a 72-pulse rectifier that involves two transformers and two diode bridges (six diodes for each bridge) in order to reduce the Total Harmonic Distortion (THD) of the main and transformer currents and enhance the output DC voltage. The proposed wind water pumping system is demonstrated using MATLAB and Simulink to show the performance of the proposed system.


During 1988, the Institution of Engineers, Australia sponsored an Australia-wide design-and-build competition for second-year students in mechanical engineering courses. Students from 18 of the 22 eligible campuses took part. The project task was to work in groups of 2-4 to design and build a device to ascend a vertically-hanging rope in minimum time, carrying a payload comprising a table-tennis ball resting unsecured in a plastic saucer. Local heats were run to determine the best entry from each campus and the campus winners competed in the national final, which was run as part of a major engineering conference. The competition was considered to be highly successful . Student interaction on-campus, between campuses and with the profession was an important benefit. Diversity of design was demonstrated by at least 8 different concepts used at campus level. Five of these were represented at the finals, where the benefits of simplicity and efficiency of one particular concept eventually became evident. The competition was strongly supported by design staff at the various campuses. Seventy-two percent (72%) of these staff members considered that the majority of students benefited from the project, 94% considered that the learning experience justified the staff and student time and effort expended and 89% favoured a similar project in future years.


The final investigation report is to develop a business plan for the creation of the company Recitec SAS to provide the collection service WEEE (Waste Electrical and Electronic Equipment) and further processing and reuse.


The three-body final-state reaction of charged single-pion production, $pp\ensuremath{\rightarrow}{\ensuremath{\pi}}^{+}\mathrm{pn}$, and that for charged double-pion production, $pp\ensuremath{\rightarrow}{\ensuremath{\pi}}^{\ensuremath{-}}{\ensuremath{\pi}}^{\ensuremath{-}}pp$, have been studied at ${T}_{P}=800$ MeV by measuring the momentum spectra for ${\ensuremath{\pi}}^{+}$ and ${\ensuremath{\pi}}^{\ensuremath{-}}$ emitted from proton-proton collisions. The momentum spectra for single-pion production are fit with the peripheral model calculations of VerWest, and a similar model by one of us is discussed. The spectra for double-pion production follow an extrapolation of the Lindenbaum and Sternheimer model from higher energies toward threshold. This result is in disagreement with the results of Cochran et al.


'mainstream' philosophical reflections and essays, he has published books on medical ethics, health promotion and medical education, and has taught medical, dental and nursing students for more than a decade. Downie is clearly continuing the tradition of his predecessors in the Glasgow Chair, such as Adam Smith, who embraced an extended public role for philosophy. The roots of this anthology lie in


Operating in a dynamic global environment, Steelcase Inc. recognized it needed to get a better handle on supply risk. The solution was an initiative called the Global Procurement Process. This comprehensive approach to risk management is built on two core principles : "begin with the end in mind" and "manage suppliers and risk throughout the lifecycle of the process."


Aiming at the tactical and technological requirements on nuclear submarine and its specific moving characteristics, the impact of its regular motion on the natural circulation driving force of its first loop is discussed. The results with respect to integrated reactor and dispersed reactor are given respectively and some corresponding conclusions are drawn which is of significant importance to the management of the nuclear power unit of submarine especially for the system with request of natural circulation.


Background: The incidence of HIV/AIDS is increasing. In 2015 there were 30,935 new cases, 41,250 in 2016 and 33,660 in 2017, where new case findings were also found in children aged less than 4 years and caused child deaths worldwide in 2011 to reach 230,000. At present there is no treatment that can cure the disease, so various efforts are made to support the health and quality of life of sufferers. The purpose of this study was to analyze the effect of providing a combination of avocado juice and storytelling therapy on the weight of a child with HIV / AIDS. Subjects and Method: This was a quasy-experimental with pre-post test design. A sample of 15 children with HIV/AIDS was selected for this study. The dependent variable was body weight. The independent variable was a combination of avocado juice and storytelling therapy. Weight data was measured using weight scales. Data were analyzed using the Wilcoxon test. Results: Body weight (kg) after intervention (Mean= 26.17; SD= 9.30) was slightly greater than before intervention (Mean= 25.30; SD= 9.16), with p= 0.002. Conclusion: Combination of avocado juice and storytelling therapy increased body weight in children with HIV/AIDS. Keyword s : storytelling therapy, avocado juice, children with HIV/AIDS Correspondence:  Warsini. Nursing Academy of Panti Kosala, Surakarta, Central Java. Alamat Instansi Jl. Raya Solo-Baki KM. 4 Gedangan, Grogol, Sukoharjo, Jawa Tengah. Email: warsinimulyono@gmail.com. Mobile: 0816418071 Indonesian Journal of Medicine (2020), 05(02): 148-152 https://doi.org/10.26911/the¬ijmed.2020.05.02.09


Data on muon-pair production by pions are used to determine the momentum distribution for valence quarks in the pion. The shape of a nucleon structure function is also obtained and is compared with a calculation based on existing data.


Nation‐wide surveys in Israel in 1960 and 1966 disclosed 295 patients with multiple sclerosis (MS). Brainstem signs were found in 14 per cent at the onset of the disease and 65 per cent during the course of illness. Cranial nerves supplying extraocular muscles were the most commonly affected. Development of cranial nerve signs was not influenced by sex, age at onset, duration of illness or ethnic origin. Patients with cranial nerve signs tended to have a remittent course. Patients with cranial nerve involvement had a mortality similar to those without such involvement. However, bulbar involvement was associated with an increased death rate. The literature on trigeminal and glossopharyngeal neuralgia, facial paralysis and deafness as well as other cranial nerve involvement in MS is reviewed.