A lossy source coding problem is studied in which a source encoder communicates with two decoders, one with and one without correlated side information with an additional constraint on the privacy of the side information at the uninformed decoder. Two cases of this problem arise depending on the availability of the side information at the encoder. The set of all feasible rate-distortion-equivocation tuples is characterized for each case. The difference between the informed and uninformed cases and the advantages of encoder side information for enhancing privacy are highlighted for a binary symmetric source with erasure side information and Hamming distortion.


An effective field theory is derived for the normal metal-to-superconductor quantum phase transition at T=0 . The critical behavior is determined exactly for all dimensions d{gt}2 . Although the critical exponents {beta} and {nu} do not exist, the usual scaling relations, properly reinterpreted, still hold. A complete scaling description of the transition is given, and the physics underlying the unusual critical behavior is discussed. Quenched disorder leads to anomalously strong fluctuations in T{sub c} which are shown to explain the experimentally observed broadening of the transition in low-T{sub c} thin films. {copyright} {ital 1997} {ital The American Physical Society}


not know their baby much better than clinicians do. In conclusion, then, we are not convinced that "postponed withholding" is the solution to the ethical challenge of deciding about resuscitation for very premature newborns. However, it does point to where the real ethical heat lies—namely, how much weight should be given to parents' wishes for resuscitation or continued ventilation when clinicians believe this is wrong for the baby.


OBJECTIVE
Diabetic retinopathy affects >60% of people with type 2 diabetes during the first 2 decades of the disease and is ameliorated by good glycemic control. This study tested whether intensive diabetes case management could prevent or delay diabetic retinopathy in patients with established type 2 diabetes.

RESEARCH DESIGN AND METHODS
This study was part of a randomized, controlled clinical trial of diabetes case management in type 2 diabetes in southern California counties serving low income ethnic minority populations. Subjects were randomized to intervention (diabetes case management) or control (traditional treatment) groups. Subjects with at least two retinal photographs (n = 149) were included in this analysis to assess the effect of intervention on development or progression of diabetic retinopathy.

RESULTS
Progression of retinopathy in the intervention group was not significantly less than in the control group (P = 0.226). However, those in the intervention group with no evidence of retinopathy at baseline were less likely to develop diabetic retinal changes (5/48) during a mean follow-up of 23.1 months than those in the control group (10/34, chi(2) = 4.805, P = 0.028). This difference remained significant in a logistic regression model that controlled for potential confounders (odds ratio 5.35 [95% CI 1.14-25.12]).

CONCLUSIONS
This study shows that a relatively short duration of case management instituted before the onset of clinically identifiable retinopathy significantly diminished the risk of developing retinopathy in patients with type 2 diabetes. The findings also emphasized the retinal disease burden in this population, with development and progression of retinopathy occurring in <2 years.


" Pathology " is a name which has been somewhat loosely applied to biological processes which are abnormal or unusual. A departure from the norm, however, is not necessarily something which has to be combated. Thus inflammation, though included under the heading of pathology, is a quite right and proper process in so far as it proves effective. If we wish to understand the behaviour of any part of an organic system (let us say, the behaviour of an organ, a tissue, a cell, or even of an " organism " in the usual acceptation of the term), we must not merely consider it as acting upon or being acted upon by its immediate present environment; we must consider also its original inheritance or " nature," and its individual past record or history. It is ultimately impracticable to look upon such an organic part as something isolated either in time or space; we frequently need, of course, to isolate it in theory for temporary purposes, but the particular point of view so gained can never of itself prove an adequate basis for efficient and comprehensive action.


The specifications of dangerous goods classification and transport package of IMDG CODE for battery was introduced and the evaluation method of dangerous goods transport for sealed wet battery was established. Test results of the dangerous goods transport package of more than 100 sealed wet battery samples were analyzed which indicated that the sealed wet battery can be dealed with nondangerous good package, if it hasn't any electrolyte leakage and is in a good condition of antishortcircuit protective package, after the tests of appearance, vibration, pressure and hightemperature.


It is clear that a chronic positive energy balance is required for the development of obesity. whether a chronic excess in energy intake of an impaired energy expenditure is the major cause of obesity has been a question. Under conditions of over feeding, an excess food energy is stored in the body, mainly as lipid in adipose tissue. The control of energy expenditure plays a smaller role in body weight regulation than the control a food intake. strategy for body weight control 1. Restrict diet 2. Behavior and lifestyle modifieations 3. Drugs : anorectic effects - catecholamine anorectics - serotoninergic anorectics 4. Physical exercise. 5. Surgery : Liposuction, Lipectomy : Gastric surgery, jaw wiring The retrospectiye study of 893 patients for 6 years between october 1988 to september 1994. The selected patients in this study were 309 in number. all of them were kmale with complication of osteoarthritis of Knee,. The drugs of choice were the combination between the catecholamine anorectic, and drugs acting on central serotoninergic pathway, afterr three months of treatment the body weight loss 4 kilogrammes,the arthritis of kness improved.


We compare two ways of constructing confidence intervals for the moments-matching parameter estimates of a Gaussian spatio-temporal Ornstein-Uhlenbeck process. It was found that those obtained via pairwise likelihood approximations had lower coverages and were more prone to the curse of dimensionality as opposed to those from a parametric bootstrap procedure.


The Textiles Environment Design (TED) project at Chelsea has since 1996 sought to explore the role that the textile designer can play in creating textiles that have a lower impact on the environment, (www.tedresearch.net. Research published by the Design Council in 1998 showed that if designers make informed and appropriate design decisions at the beginning of the chain, then the environmental performance of any product can be improved by up to 90%. Most other research projects look to make improvements within production and manufacture, ('Well dressed?' 2006, Sustainable Manufacturing Group, Institute for Manufacturing at Cambridge University). TED is unique in that its focus is on the impacts created by the designer.

'Well Fashioned' was the first survey of high-end, well designed and made eco fashion design in the UK, which was the result of research conducted by Earley since 2004 and compiled within the TED Resource at Chelsea. Other exhibitions have attempted similar presentations, but either:

·showed poor quality workmanship ('Remade at Traid', London), or
·focused on the larger fashion labels ('Verdopolis: The Future Green City', New York, 2005), or
·failed to show clothing at a 'high-end' or couture level ('Ethical Fashion Show', Paris, 2004).

'Well Fashioned' considered work made for all stages of the lifecycle of the product: the manufacture, the use, and the disposal of clothing. As curator and an exhibitor, Earley created the format and selected content for the exhibition, and also produced and commissioned new research projects and accompanying texts. The exhibition and website has become a key source for researchers and designers, as the record visitor numbers and extensive national and international press coverage confirms: "Earley has brought passion and dynamism to the Crafts Council, raising a flag for craft and design examined in a profound way." (Suzy Menkes, International Herald Tribune)


Wound healing activity of E uphorbia nivulia Buch.-Ham. (Euphorbiaceae) was evaluated using excision wound model in albino mice by applying latex topically on the area of excised wound once a day for 23 days. Plant latex significantly enhanced the rate of wound contraction and period of epithelialization, which is comparable to Soframycin. Latex of this plant significantly reduces the bleeding and whole blood clotting time. Phytochemical analysis revealed the presence of alkaloids, cynogenic glycosides, phenolics, tannins and saponins. The latex of Euphorbia nivulia possesses natural ingredients capable of arresting wound bleeding and accelerating wound healing properties which suggests healing potential to cure wound.


In experiments in which rabbits are to be given atropine or certain atropine‐like agents, it is important to select animals whose plasma is deficient in the enzyme tropinesterase (atropinesterase). Three simple procedures for assessing the presence of this enzyme in rabbits in vivo have been examined. It is concluded that a different procedure is needed for albino rabbits than for animals with dark irides. In this way, 95–98% correct assessments of the presence or absence of tropinesterase have been made by simple procedures within 1 hr. Fully reliable assessments could only be made by in vitro methods, two of which (one quantitative and the other qualitative) are described. The latter enabled a reliable all‐or‐none assessment of tropinesterase activity to be made with only 0·'02 ml of plasma within 1–2 hr.


The paper utilized high-temperature instantaneous gelatinization technology as a substitute for the traditional steaming technology.By measuring several indexes,such as water content,starch gelatinization ratio,enzymatic hydrolyzeα- amino nitrogen content and total fat content,the variations in the process of these indexes were obtained.Then corresponding models were set up based on artificial neural network.It could be concluded that established models are quiet accrate and can disclose the relationship among operating conditions and indexes by evaluation of two types of data(trained data and untrained data).


A present status of utilizing the reference system of patients' transfusion information during the 19 months from May 1, 1984 to Nov. 30, 1985 was monitored in Kyoto University Hospital. The reference frequency was 6411 in the Blood Transfusion Service and 476 in the polyclinic divisions, and was approximately constant in the former but high in June and July in the latter. The results of the transfusion examination and the transfusion histories of patients were the reference items with almost equal frequency in the Blood Transfusion Service but the latter was the major one in the polyclinic dividions. A high significant correlation (r=0.87) was observed between the reference frequency and the supplied units of the blood preparations in each clinic division. To clarify the reason of the low reference frequency in the polyclinic division, the doctors' opinions about the reference system were researched. Only 58% of the doctors had the license necessary for the reference and 41% of the doctors did not know about the reference system. Thus, the low reference frequency seems to be ascribed to the facts that PR for the doctors about the reference system is lacked, and that the rate of the doctors have the license for the reference is 58% and that the doctors in the clinical division were informed of the results of each transfusion examination by another transmission procedure.


Objective To establish a method for the determination of starch/glucose/sucrose in heroin. Method The samples of heroin mixed with starch, glucose and sucrose were analyzed by FTIR. Result Starch/glucose/sucrose in heroin have been detected. Conclusion FTIR can be used to identify starch/glucose/sucrose in heroin.


Background: Livedo reticularis (LR) is a skin disorder characterized by a reddish‐blue mottling of the skin in a "fishnet" reticular pattern. The aim of this study was to investigate the major histopathological characteristics of LR and determine whether the histopathology of LR is more common in whitish areas or in the erythematous areas.


In recent years, many efforts have been done to account for the non-Gaussianity of the intensity signal in diffusion Magnetic Resonance Imaging (MRI). In particular, various estimation methods for the Diffusion Tensor Imaging (DTI) model have been extended to the Rician noise model, which arises from taking the modulus of a single complex signal, assumed to be Gaussian in both its real and imaginary component. The Rician model is effective in accounting for the signal skewness at low Signal-to-Noise Ratios (SNRs), but the assumptions for its validity are violated in presence of multi-coil scanners (or multi-channel coils). If the signals received by the N coils are combined by sum of squares, the intensity signal follows a scaled noncentral chi distribution with 2N degrees of freedom. Moreover, the literature suggests that different signal combination methods, as for example adaptive combine, yield signal distributions that still follow approximately a noncentral chi law, but with a lower number of degrees of freedom with respect to twice the number of coils.
In this work we present a framework for accounting for the distribution of a multicoil signal under the DTI model.
First, we propose a hypothesis test-based method for discriminating background from signal voxels, basing on the noise distribution, with the possibility of accounting locally for the apparent number of coils. This method, other than finding a "mask" for the MR image that individuates areas with relevant diffusion properties, provides a bound for the estimation of the noise dispersion parameters, thus allowing to improve the following estimation under the DTI model. The noise discrimination test is validated on real brain data, addressing in this specific case the issues related to the intialization of the method.
Moreover, we propose a method for estimating the diffusion parameters of the DTI model in noncentral chi-distributed signals. Diffusion parameters are estimated accounting also for the local noise dispersion and a spatially-varying number of coils. Practical implementation details are provided, to overcome computational and mathematical coherence problems like dealing with Bessel functions. The performance of this method is then compared to other existing ones, like loglinear or Rician estimation.


The paper describes an educational project on teaching rhetoric at the university level as part of practical rhetoric workshops. What makes this didactic proposal innovative and unique is the incorporation of improvisation tools in rhetoric classes. The aim of the article is to demonstrate how techniques from contemporary improvisational theatre help students improve their communication skills. The article begins with a brief overview of rhetorical education at Polish universities and a description of basic rhetorical competences related to the creation and analysis of texts. An introduction to improvisational theatre and the specifics of improvisation workshops are presented. Then, a proposal is made to combine these different approaches to the development of communicative competences in a series of workshops. Two exercises are presented, representative of the entire workshop series and devoted to the categories of ethos and narration. The benefits of using this method are discussed by showing the learning outcomes as a specific connection between communicative competences and the mechanisms of understanding rhetorical categories.


The purpose of this study was to analyze the multiple regression between the psychological well-being, Empathy ability Scale and Job Efficiency at relationship among on Teacher`s job satisfaction among elementary, middle, high the whole country. It aims to find a method that can improve teacher`s job satisfaction. The subjects for this study were 308 teacher`s composed of 196 out of elementary school teachers, 62 out of middle school teachers and 50 out of high school nation wide. The result and discussion are as follows:First, if we take a look teacher`s psychological well-being, Empathy ability Scale and Job Efficiency autonomy and school administration, compensation system, personal growth and school administration, compensation system, working environment, purpose of life and school administration, positive interpersonal relationships, self acceptance among subordinate variables of psychological well-being, empathy ability scale, job efficiency of teachers at are all relevant to of subordinate variables except compensation system. Second, as a result of the multiple regression analysis, the significant variables which affect teacher`s job satisfaction are ranked in the order of human relationships, self acceptance, emotional factors. whole all variables are not significant.


Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening hyperinflammatory syndrome characterized by overactivation of the immune system due to systemic release of proinflammatory cytokines, especially of interferon gamma (IFNγ), and persistent activation of macrophages/histiocytes and T cells. Emapalumab, a fully human, anti-IFNγ monoclonal antibody that binds to both free and receptor-bound IFNy, neutralizing its biologic activity, was approved by the Food and Drug Administration (FDA) in 2018 for the treatment of adult and pediatric patients with primary HLH with refractory, recurrent or progressive disease or intolerance with conventional HLH therapy. The safety and efficacy of emapalumab was based on results from a pivotal phase 2/3 trial which reported a 63% overall response in patients treated with emapalumab. Since approval, no study has evaluated the use of emapalumab in a larger cohort of patients in the real-world clinical setting.
 Aim: To assess real-world treatment patterns and outcomes, clinical and demographic characteristics among patients treated with emapalumab.
 Method: This retrospective, non-interventional, observational medical chart review study will include patients treated across treatment centers in the US with emapalumab in a non-clinical trial setting. The study aims to include more than 100 patients who have been treated with at least one dose of emapalumab between November 20, 2018 and December 31, 2020 (patient identification period). The date that the patient initiates treatment with emapalumab within the patient identification period is defined as the index date. The post-index date is defined as the period from the index date through to the study end date (June 30, 2021), end of data availability for the patient, or date of death, whichever occurs first. Patients will be classified into three groups (i.e. primary HLH, secondary HLH, or non-HLH) based on the information obtained from their charts, the HLH 2004 diagnostic criteria, and adjudication by the REAL-HLH Steering Committee.
 Results: The primary objective of the study is to describe treatment patterns in patients with HLH treated with emapalumab in a real-world clinical setting, including emapalumab dose, treatment duration, and reasons for initiating or discontinuing treatment. The secondary objectives are to describe demographic and clinical characteristics of patients with HLH treated with emapalumab, and their outcomes. The exploratory objectives include detailing the demographic, clinical characteristics, treatment patterns, and outcomes of patients with non-HLH clinical conditions treated with emapalumab (Table 1). Demographics and clinical characteristics will be analyzed at the time of diagnosis. Treatment patterns and outcomes will be analyzed during the post-index date.
 Conclusion: The study aims to assess treatment patterns and outcomes, clinical and demographic characteristics among patients treated with emapalumab, a novel IFNγ blocking agent, in real-world clinical settings in the US.
 Figure 1 Figure 1.

 Allen: Sobi: Consultancy. Leiding: Sobi: Consultancy. Chandrakasan: Sobi: Consultancy. Walkovich: X4 Pharmaceuticals: Other: Local PI for clinical trial involving mavorixafor and patients with neutropenia; Swedish Orphan Biovitrum AB (Sobi): Consultancy, Honoraria; Pharming: Honoraria, Membership on an entity's Board of Directors or advisory committees; Horizon Pharmaceuticals: Honoraria, Membership on an entity's Board of Directors or advisory committees. Oladapo: Sobi: Current Employment. Yee: Sobi: Current Employment. Pednekar: Sobi: Consultancy; PRECISIONheor: Current Employment. Raza: Sobi: Consultancy; PRECISIONheor: Current Employment. Jordan: Sobi: Consultancy.


T HE SIGNIFICANCE and prognostic value of the exercise test in coronary heart disease remain controversial. Robb and associates1 found significantly higher rates of death and occlusion in those with a positive test and stated that a negative response to the double two-step exercise test excludes, for practical purposes, the presence of latent coronary insufficiency and clinically significant narrowing of the coronary arteries. Lepeschkin2 reported that a completely normal electrocardiographic response to the double Master exercise test indicates with great probability that no major coronary stenosis is present, or, if present, it is well compensated by collateral circulation. Wood and associates3 permitted 100 patients with classical angina pectoris to exercise until symptoms developed and obtained an isehemic response in 88 per cent. Scherf4 stated that it is apparently impossible to exclude false-negative tests and that any conclusion as to prognosis, based on the outcome of an exercise test, is unjustified. The type of response to exercise in which the S-T segment is depressed 0.5 mm. or more below the P-R or P-Q junction in a horizontal or sagging course has been described as significant of myoeardial isehemia by Wood and associates3 and by Myers and Talmers.5 Robb and associates1 found this to be the best and only unequivocable criterion for a positive test. Brody6 examined 756 business executives free of clinical coronary heart disease and found 23 with this ischemic type of response. Definite coronary artery disease later developed in 70 per cent of these 23 men. Myers and Talmers,5 Robb and associates,1 and Brody6 all found that S-T junctional depression, if deep and not due to tachycardia, could indicate myocardial ischemia in some cases.


Metabolic fluxes are governed by physical and economic principles. Stationarity constrains them to a subspace in flux space and thermodynamics makes them lead from higher to lower chemical potentials. At the same time, fluxes in cells represent a compromise between metabolic performance and enzyme cost. To capture this, some flux prediction methods penalise larger fluxes by heuristic cost terms. Economic flux analysis, in contrast, postulates a balance between enzyme costs and metabolic benefits as a necessary condition for fluxes to be realised by kinetic models with optimal enzyme levels. The constraints are formulated using economic potentials, state variables that capture the enzyme labour embodied in metabolites. Generally, fluxes must lead from lower to higher economic potentials. This principle, which resembles thermodynamic constraints, can complement stationarity and thermodynamic constraints in flux analysis. Futile modes, which would be incompatible with economic potentials, are defined algebraically and can be systematically removed from flux distributions. Enzymes that participate in potential futile modes are likely targets of regulation. Economic flux analysis can predict high-yield and low-yield strategies, and captures preemptive expression, multi-objective optimisation, and flux distributions across several cells living in symbiosis. Inspired by labour value theories in economics, it justifies and extends the principle of minimal fluxes and provides an intuitive framework to model the complex interplay of fluxes, metabolic control, and enzyme costs in cells.


Thesensiti vity anduncertaintyestimatesof aregionalmodelto aselectedsetof lumpedanddistributedparametersis determinedusingthefirst ordermethod, the Rosenbluethmethodand the Latin Hypercubesampling(LHS) method. Evapotranspiration(ET) crop coefficientsis identifiedin the studyasthe parametermostsensiti ve to the output, followed by roughness.Singularvalue decompositionis usedto determinepossiblegroupingof parameters. INTRODUCTION Parameteruncertainty, combinedwith input uncertaintyandthealgorithmuncertaintyareresponsiblefor the total modeluncertainty. Regionalhydrologic modelsfor SouthFloridauselargenumbersof distributedparametersuchas ET cropcoefficientsandflow roughnesswhich changewith local naturalconditions,andcannotbedeterminedwith precision.Model outputsalsodepend on topographicelevations, river widths, detentiondepthsand other features which cannotbedeterminedthroughdirectcomputations.Thestudyis aimed at determiningthesensiti vity of selectedmodeloutputsto someof theparameters.Model sensiti vity analysisprovidesanopportunityto studythebehavior of physicalsystemsto varyingnaturalandman-madeconditions. METHODSOF ANALYSIS Thesimplestmethodfor sensiti vity analysisis thefirst ordermethodin which


There are diverse species of macro algae in Tanjung Tuan, Port Dickson that include the division of Phaeophyta such as Padina gymnospora (Kutzing) Vikcers, Sargassum baccularia C. Agardh, Sargassum binderi Sonder, and Turbinaria conoides (J. Agardh) Kutzing together with the division of Chlorophyta such as Caulerpa lentillifera J.Agardh and Caulerpa racemosa (Forsskal) J. Agardh. Nutritional compositions of samples collected were determined. Content analysis of moisture, ash, protein, carbohydrate, crude fiber, fat content, vitamins (vitamin A, vitamin B₁, vitamin B₂, vitamin C, Niacin) and minerals (phosphorus, sodium, potassium, calcium, iron, magnesium, copper and zinc) of the selected macroalgae had been carried out using standard methods. Comparisons with corresponding nutrient values in several commonly consumed local vegetables (spinach), local macro algae e.g. Gracillaria changii and macro algae or macroalgae derived-products from other countries e.g. Dulse, Irish Moss, Kombu, Nori, Wakame, seaweed agar (raw) were done. Turbinaria conoides showed the overall. best reading compared to five other species because it showed higher contents of ash (4.7 %), vitamin A (24.1 mg/kg, 80333 IU), niacin (274 mg/kg), sodium (13085 mg/kg), potassium (21137 mg/kg), calcium (2353 mg/kg), magnesium (4026 mg/kg), copper (25.2 mg/kg) and zinc (49.1 mg/kg).


A 12-month study was conducted in the southern rangelands of Ethiopia on the mineral status of Boran zebu cattle and their responses to supplementary P and Cu. The forages were marginal-to-deficient in Na, P and Cu (respectively 0.12 g kg −1 , 1.6 mg kg −1 and 6.8 mg kg −1 ), probably due to the very low levels of these elements in the soil. Ca serum concentration at an average level of 5.1 mg (100 ml) −1 represented an acute hypocalcaemic condition, though it is not clearly understood whether this was a serious metabolic deviation in the breed or what consequences it could have


The photoluminescence quantum efficiency of semiconductor nanocrystals at room temperature was markedly enhanced about 50 times by surface treatment of the nanocrystals after synthesis, and the original photoluminescence peak position and narrow line width were maintained. Simply, the nanocrystal surface was treated with a small amount of sodium borohydride (NaBH4) in toluene at room temperature. The surface-treated nanocrystals showed very high quantum efficiency, up to 75%, even in the blue region of 490 nm. The TGA and XPS data revealed that some of the surfactants on the nanocrystal surface were removed by the reaction with NaBH4 and that the exposed cadmium on the surface was converted to cadmium oxide. The cadmium oxide functioned as a robust passivation layer on the CdS surface and contributed more electron density toward the inside of the CdS core to enhance exciton recombination. The surface treatment was powerfully effective in improving the quantum efficiency of II−VI compound semiconductors su...


We propose a novel method of incorporating physical knowledge as an additional input to the discriminator of a conditional Generative Adversarial Net (cGAN). Our proposed approach, termed as Physics-informed Discriminator for cGAN (cGANPID), is more aligned to the adversarial learning idea of cGAN as opposed to existing methods on incorporating physical knowledge in GANs by adding physics based loss functions as additional terms in the optimization objective of GAN. We evaluate the performance of our model on two toy datasets and demonstrate that our proposed cGAN-PID can be used as an alternative to the existing techniques.


Adaptive antenna subset selection can improve the expected theoretical capacity of a multiple-input, multiple-output (MIMO) wireless channel, whilst maintaining the tractable complexity of the lower order MIMO system. This paper seeks to explore the effects of delayed selection using measured indoor channel data at 5.2GHz, reflecting more accurately the situation facing a real-time system. Several selection schemes are considered and results show that delayed selection, while not as effective as instantaneous selection, can still improve the expected capacity by a significant margin.


Abstract Poster session 1, September 21, 2022, 12:30 PM - 1:30 PM Objectives The aim of this study was to characterize the Candida spp. isolated from blood cultures and determine the antifungal susceptibility pattern of the Candida species prevalent in a tertiary care hospital in North India. Methods This retrospective study was conducted in Department of Microbiology of a tertiary care hospital in North India from April 2020 to March 2022. All blood cultures received in the department during this period were included in the study. Candida species isolated were identified and antifungal susceptibility testing was performed by VITEK as per standard protocol, The susceptibility pattern of 50 isolates was also performed by the broth microdilution method as per Clinical and Laboratory Standards Institute guidelines (CLSI) and the results were compared with VITEK results. Results Out of 21 804 blood cultures received during this period, 177 grew Candida species. Therefore, the overall prevalence of Candida species was 0.81% in our study. The incidence of bloodstream infection caused by non-albicans Candida species (80%) was higher than C. albicans (20%). Among NAC species, C. tropicalis (45%) was the most common, followed by C. pelliculosa (15%). Candidemia was predominantly observed in ICU patients. Resistance was seen in 14.1% isolates to voriconazole and fluconazole, 4.2% to flucytosine and 3.9% to caspofungin and amphotericin-B. No resistance was seen to micafungin. A total of 15% of the isolates were resistant to more than one drug. Conclusion There was a predominance of non-albicans Candida over C. albicans. Maximum resistance was seen to voriconazole followed by fluconazole. Continuous surveillance is necessary to follow trends and monitor changes in epidemiological and resistance patterns in different geographical regions, especially in critically ill patients.


Francois Taddei raises confidence as the basis of creativity and the production of scientific works; proposes work in classrooms and laboratories as a means of achieving depth in research and presents its initiative to advance careers, masters and doctorates from the motivation of students.


Problems associated with provision of food in quantity foodservices prompted the development and use of prepared food items processed in retortable trays. Consumer acceptance of such foods was required so that the items could be screened for foodservice application. Consumer tests, using small portion samples and sensory testing under laboratory conditions, gave a relatively reliable prediction of acceptability of most of the items under extended-use consumer testing during a field trial. Final field acceptance of some items was influenced by external factors not accounted for in laboratory testing.


AIM To examine whether an elevation of total plasma homocysteine is a risk factor for coronary heart disease and stroke. METHODS The study involved 173 patients with hyperhomocysteinemia and selected healthy subjects of matching age and sex. The incidence of coronary disease and stroke was observed during the one-year follow up. RESULTS The incidence of coronary disease was 3.6% in hyperhomocysteinemia patients and 0.6% in the control(RR:3.0,95% CI: 0.4 to 5.5, P0.05), and that of stroke was 4.1% in the patients and 0.6% in the control(RR:3.5,95%CI:0.7 to 6.4, P 0.05). Both coronary disease and stroke occurred in 7.7% of the patients, while in 1.2% of the healthy subjects ( RR:6.4, 95% CI:2.7 to 10.1, P0.01). CONCLUSION Hyperhomocysteinemia is a risk factor for coronary disease and stroke.


According to Peter Evans, the relationship between states and development can be analyzed by applying one of two typologies: predatory or developmental states. The characteristics of predatory states include victimizing and intimidating citizens; profiting from society and its resources without offering suitable services in return; giving no weight to the increased accumulation of wealth; enjoying despotic power; feeling no need to negotiate with social and political groups; the existence of an inefficient bureaucracy; governmental opposition to citizens' political participation; preventing the emergence of social groups interested in social change; preferring individual interests to collective interests; tolerance of corruption; excessive regulations; and assigning managers for all economic and political sectors. In contrast, the characteristics of a developmental state include political dependence on society; continuous negotiations over goals and policies of civic institutions; supervising economic transitions; preferring collective to individual interests; an efficient bureaucracy based on meritorious appointments; an active role in substructure fields; and encouraging education. A developmental state relies on society and is responsible for its social environment so that the state and social groups carry out joint projects to initiate change. Developmental states may be classified into three types based on the way in which the state communicates with and plays a role in the growth of civil society. These types are obstructionist states, equivocal states and developmental states. The relationship between each kind of developmental state and social changes that have their roots in structural reforms is defined according to their approach to structural reforms. Equivocal states, for example, resist such reforms. Iran's Qajar monarchy (1796–1925) was an example of such a state. Even though Qajar shahs promoted certain forms of development, they vehemently objected to the growth of an industrial bourgeoisie, resisted structural reforms and national movements that threatened their own powers, and led Iran to the brink of economic recession, underdevelopment and despotism. Equivocal states do undertake structural


The invention discloses a high-performance crosslinked ethylene and tetrafluoroethene copolymer insulated cable and a preparation method thereof. The insulated cable comprises a lead (1), an insulation sleeve (2), a shielding sleeve (3) and a sheath (4), wherein the insulation sleeve (2), the shielding sleeve (3) and the sheath (4) sleeve the lead (1) successively from inside to outside, the insulation sleeve (2) and the sheath (4) include crosslinked ethylene and tetrafluoroethene copolymer sleeves respectively, and the shielding sleeve (3) is a silvered aramid fiber braided sleeve. The insulated cable prepared by the method is high in insulatiing, mechanical and radiation-hardening properties and is chemically stable in the vacuum environment.


A method and device as well as use thereof for sterilization of implements. Using a cycle comprising a first spraying with cold water, a spraying with sterilizing fluid and a second spraying with cold water. The cold water and the next customized equipment and the liquid is sprayed onto the tools via the difference nozzles (7, 8)


BACKGROUND
Once-weekly dosing of recombinant human erythropoietin (rhEPO) in patients with myelodysplastic syndromes (MDS) has not been investigated thoroughly. We performed a clinical trial to evaluate the effects of this new dosing regimen in patients with MDS who were unresponsive to the conventional three-times-weekly schedule.

PATIENTS AND METHODS
Forty-eight patients with low- or intermediate-risk MDS were enrolled in a 12-week study. rhEPO alpha (rhEPOalpha) was administered once-weekly by subcutaneous injection with a starting dose of 40,000 U fixed dose. The drug dosage was increased to 60,000 U fixed dose if after 6 weeks there was no or suboptimal erythroid response.

RESULTS
Clinically significant responses were seen in 13 (27%) patients, with 11 improving their response after dose escalation of rhEPOalpha. Only one patient (case 23) maintains a response after a follow-up period of 14 months. All other patients had responses lasting between 10 and 43 weeks, with a median time to relapse of 20 weeks. Treatment was well tolerated, with no relevant adverse events. Response to therapy was associated with significantly higher concentrations of circulating erythroid blast-forming units and a decrease of the bone marrow fraction of apoptic CD34+ cells.

CONCLUSIONS
Once-weekly rhEPOalpha therapy results in an improvement of erythropoiesis in a subset of MDS patients who are unresponsive to conventional dosing, and may act by inhibiting apoptosis of erythroid precursors. These results warrant further investigation of this dosing regimen either alone or in combination with other agents.


J. M. Coetzee's Foe , one of the most discussed of his novels, is known for its inter-textual relationship with Defoe's Robinson Crusoe and Roxana . But despite the substantial body of criticism devoted to examining Foe 's intertextuality, the allusions it makes to Crime and Punishment at crucial moments in the narrative have not so far been spotted. This essay argues that Dostoevsky's novel is of greater structural importance to Foe than those of Defoe, and that Foe 's allusions to Dostoevsky enable an understanding of its hitherto ba¥ing ending. It shows how the presence of Crime and Punishment in the text relates to the literary-critical study of Dostoevsky that Coetzee made just prior to composition, and argues that his engagement with Dostoevsky enjoins us to examine Foe more rigorously in terms of its handling of literary genre, particularly that of the novel itself. Through Dostoevsky a new reading of Foe emerges that throws the more established ways of dealing with the text into doubt; it becomes more complex, more witty, and more stubbornly paradoxical than previous criticism has been able to acknowledge. Seen from too remote a vantage, life begins to lose its particularity. All shipwrecks become the same shipwreck, all castaways become the same castaway, sunburnt, lonely, clad in the skins of the beasts he has slain.The truth that makes your story yours alone, that sets you apart from the old mariner by the ¢reside spinning yarns of sea-monsters and mermaids, resides in a thousand touches which today seem of no importance.


The kinetic behavior of the liquid-phase oxidation of cyclohexane was investigated in a bubble column under 1.1 MPa at various temperatures,in which gases with O2 concentrations ranging from 5% to 99% were used as oxidants.By comparing the non-catalytic and catalytic oxidation of cyclohexane,the free radical mechanism of the oxidation was discussed in detail.Both the mechanism analysis and experimental data showed that the catalyzed liquid-phase oxidation of cyclohexane was a reaction of first-order with respect to both cyclohexane and oxygen.For the non-catalytic oxidation,an induction period was obvious.During the non-catalytic oxidation of cyclohexane by oxygen,the chain initiating reaction was the rate determining step.Beyond the induction period,the reaction was accelerated and exhibited auto-catalytic behavior due to the release of radicals through the decomposition of cyclohexyl hydroperoxide when its concentration accumulated to a certain degree.On the other hand,in catalytic oxidation the cyclohexyl hydroperoxide decomposed rather quickly,and then accelerated the reaction.And during the reaction,the concentration of cyclohexyl hydroperoxide kept very low and the chain propagation became the rate limiting step.


Article history: Received 30 October 2018 Received in revised form 1 December 2018 Accepted 5 December 2018 Available online 10 January 2019 Volume thermal expansion measurement of the solid is one of the most challenging issue in material industry especially when the solid is in big size. The existing instruments such as dilatometer has a limitation to determine the volume thermal expansion of material. Therefore, a new and precise system has been proposed to determine the volume thermal expansion. In this study, several samples such as gold and tungsten were used to determine its volume thermal expansion by using custom made hydrostatic weighing system (HWS) where the experimental results show that the HWS can determine the volume thermal expansion. Volume thermal expansion value for gold rod and tungsten rod are 1.5×10-4 °C-1 and 7.7×10-5 °C-1 respectively. The expanded uncertainty obtained using HWS was 0.0003 °C-1. To assure the quality of the HWS, inter-instrument comparison between HWS and dilatometer was performed. The results of the comparison show that the En ≤ 1 indicates the performance of the HWS is acceptable. Thus, this study will demonstrate on how the volume thermal expansion of the material is precisely and accurately measured using HWS. Furthermore, it is cheaper than dilatometer with reasonable accuracy and it was traceable to SI unit.


Abstract We report a structure refinement of a P21/m ferromagnesian cummingtonite crystal with Fe/(Mg + Fe) = 0.37 at 140 K; this crystal was inverted from the C2/m structure, which is stable at room temperature. The phase-transition temperature is ∼240 K. The most significant structural changes associated with the C2/m-to-P21/m phase transition are as follows: (1) one crystallographically independent O-rotated silicate chain becomes two, with the A chain S rotated and the B chain 0 rotated; (2) the M4 site collapses, with a marked decrease (0.020 Å) in the average M4-06 bond distance; and (3) the largest decrease in the isotropic displacement factor is for the M4 cation. From 295 to 140 K, total changes of 14 and 11° occur in the O5-O6-O5 kinking angles of the A and B chains, respectively. The volume of the M1 octahedron decreases more than that of the other three MO6 polyhedra, whereas the volume of the M3 octahedron is essentially unchanged. All four MO6 polyhedra become more regular as a result of the C2/m-to-P21/m transformation. These results provide new evidence that the effective size of the M4 cation controls the relative stability of the C2/m and P21/m structures. The results also provide a new explanation for the unresolved broadening of the cummingtonite Raman spectra measured at low temperatures by Wang et al. (1988).


Introduction * What is FLR and How Does it Differ from Current Approaches? * Building Support for FLR * Applying an Adaptive Management Approach in FLR * Understanding the Landscape Mosaic * Understanding Forest Landscape Dynamics * Applying a Stakeholder Approach in FLR * Identifying Site-level Options * Site-level Restoration Strategies for Degraded Primary Forest * Site-level Strategies for Managing Secondary Forests * Site-level Rehabilitation Strategies for Degraded Forest Lands * Site-level Strategies for Restoring Forest Functions on Agricultural Land * Scenario Modelling to Optimize Outcomes * Monitoring and Evaluating Site-level Impacts * Getting Started * Bibliography, Glossary, Index


Public opinion is increasingly interested in the disposal of absorbent hygiene products. Their precise chemical characterization allows to correctly consider the possibility of energy recovery from their treatment and evaluate the related gas emissions.


This paper proposes an output spike-predictable comparator based on an adaptive threshold value method (ATVM) for obtaining a low-power neuron circuit. The proposed comparator operates during the predicted time at which the membrane voltage and threshold voltage coincide. This prediction-based power-gating method can help decrease the static power consumption of the comparator. In addition, the A TVM increases the threshold in proportion to the number of output spikes, and thus, the reduced use of the main comparator further decreases the power consumption. With the 28 nm complementary $\mathbf{metal-oxide}$ -semiconductor process, a framework with 144 input layers, 25 hidden layers, and 10 output layers was trained using MATLAB®. Modified National Institute of Standards and Technology (MNIST) classification operations were conducted using 250 synapses and 10 neurons. Using the proposed comparator and ATVM, the total power consumption of the comparator could be reduced by 90.37% with a supply voltage of 1.8 V. The accuracy of the MNIST classification using the A TVM was 95.02 %.


War has been portrayed as the blood-thirsty second horseman of Apocalypse that plagues the human race. According to some estimates, only in 20th century more than 230 million people were killed or allowed to die by human decision, to use the words of the historian Eric Hobsbawm (1). Many more millions of war sufferers can be added to this tragic account: the ones injured, crippled, orphaned, bereft of their homes and families, and mentally afflicted. Psychological consequences of war are diverse and manifold, but one condition in particular has become a household word and a symbol of war survivors' mental anguish: posttraumatic stress disorder (PTSD).


Abstract During the last 2 decades, European brown hare (Lepus europaeus) populations have declined considerably. We evaluated whether this decline could have been associated with diminished overall fitness due to reduced genetic variability. We also estimated the extent of population differentiation. We typed 307 hares from 21 localities for 5 microsatellite loci and the mitochondrial d-loop. Analysis of molecular variance revealed a high degree of genetic variability, matrilinearily structured populations, male-biased gene flow, and lack of inbreeding. We did not identify any geographical or anthropogenic barriers to gene flow. Because extant populations are small and susceptible to random genetic drift, we recommend changes to current population management practices and periodic genetic surveys.


In Australia, as in other Western democracies, the category 'old age' often refers to men and women who are not only advanced in age, but who are also poor. When two Victorian psychiatrists introduced the concept 'successful ageing' into discussions on mental health in old age in the 1960s, they too drew on the experience of men and women whose lives were marked as much by hardship as advancing age. However, their use of this concept has the potential to contribute to a broader understanding of life in old age in twentieth-century Australia because it was also based on observations of changes in the experience of old age that affected all classes. This article has been peer-reviewed.


OBJECTIVE To develop an HPLC method for the quantification of huperzine A in rat plasma an d in injection site after im microspheres.METHODS Samples were extracted by liquid-liquid extraction and separated on a Kromasil -C 18( 4.6 mm× 250 mm, 5 μm).The mobile phase of drug content d etermination in plasma and muscle homogenate was acetonitrile- 0.2% triethyl amine)20∶100 and 25∶75 respectively.The detection wavelength was 310 nm.RESULTS The assay range of the two methids was 2.5~ 500 μg·L -1 and 1.0 08~ 201.6 mg·L -1 respectively.The limit of quantification was 2.5 μg·l -1 and 1.008 mg·L -1 respectively.The relative recove ry was in the range of 85%~115% and the RSD of the inter and intra-day were all less than 12%.CONCLUSION The method can be applied to evaluate the long release effect in vivo of huperzi ne A microspheres.


In this paper we have treated supervision and control of local governance in context of fair governance in Republic of Kosovo. Analyse of law framework and European standards of governance autonomy of local self-governance and administrative supervision of local governance. Treating of supervision of local authority governance and the main mechanism of government for legal administrative review of local authority governance and legality as well as the rights of the supervising authority for administrative review of legality of general acts of municipalities. The purpose of this paper is to analyse and tackle the challenges of supervision and control of local government institutions in Kosovo.The mandate and powers of the central government to review the legality of local authorities in the field of enhanced competencies and the legality and appropriateness of their scope of activities of in the field of delegated powers. The challenges of preserving the autonomy of local self-government and local government supervision by the central authorities. One of the challenges of the supervisor in the future will be to supervise and control of municipalities with extended competences (municipalities with Serb majority), shall these municipalities consider requirements to be review the unlawful acts and harmonize them with the applicable legislation in Kosovo. The methodology of the paper will be mixed, such as: as comparative methods, descriptive, requesting explanatory, predictive.


Desalination has been growing rapidly as an industry and as a field of research that combines engineering and science to develop innovative and economical means for water desalting. Many countries in the world, especially in the Middle East, depend heavily on seawater desalination as a major source of drinking water and have invested considerable efforts and financial resources in desalination research and training. Desalination plants have seen considerable expansion during the past decade as the need for potable water increases with population growth. It is estimated that the world production of desalination water exceeds 30 million cubic meters per day and the desalination market worldwide is expected to reach $ 30 billion by 2015. One of the major economical and environmental challenges to the desalination industry, especially in those countries that depend on desalination for potable water, is the handling of reject brine, which is the highly concentrated waste by-product of the desalination process. It is estimated that for every 1 m3 of desalinated water, an equivalent amount is generated as reject brine. The common practice in dealing with these huge amounts of brine is to discharge it back into the sea, where it could result, in the long run, in detrimental effects on the aquatic life as well as the quality of the seawater available for desalination in the area. Although technological advances have resulted in the development of new and highly efficient desalination processes, little improvements have been reported in the management and handling of the major by-product waste of most desalination plants, namely reject brine. The disposal or management of desalination brine (concentrate) represents major environmental challenges to most plants, and it is becoming more costly. In spite of the scale of this economical and environmental problem, the options for brine management for inland plants have been rather limited. These options include: discharge to surface water or wastewater treatment plants; deep well injection; land disposal; evaporation ponds; and mechanical/thermal evaporation. Reject brine contains variable concentrations of different chemicals such as anti-scale additives and inorganic salts that could have negative impacts on soil and groundwater. This chapter highlights the main concerns as well as the environmental and economical challenges associated with the generation of large amounts of reject brine as a by-product of the desalination process. The chapter also outlines and compares the most common options for the treatment or disposal of reject brine. The chapter focuses on a novel approach to the management of reject brine that involves chemical reactions with carbon dioxide in the


Female healthcare workers have a high prevalence of low back pain (LBP)‐related sickness absence. Here, we report findings of a 24‐month follow‐up of a previously published 6‐month randomized controlled trial (RCT).


This publication is a contribution to discussion on the geometry and petrography of the rock complex responsible for the Carpathian conductivity anomaly. We analysed arguments showing that this anomaly is caused by induction in the sedimentary basin, and make a critical review of various data to find out whether the good conductivity is connected with a rock complex containing graphite or mineralized water. We conclude that a more likely mechanism is the ionic one, i.e., the existence of fluids, although a final decision can only be made on the basis of deep drillings.


Recent initiatives by the United States government are seeking to enhance the transparency and openness of its decision finding processes. At the same time, increased use of interactive web and soc...


In this letter, we present a novel concept of virtual electric/magnetic walls which are formed by combining perfect electric conducting parallel plates and perfect magnetic conducting parallel plates. In practice, the perfect magnetic wall can be replaced with an artificial magnetic conductor surface. Two types of complementary transverse electromagnetic waveguides are built with the virtual electric/magnetic walls. The field distribution in the waveguide was simulated and measured. The existence of virtual electric wall was verified.


The kinetics of formation of α- and β-molybdosilicic acid have been investigated and rate equations proposed, together with possible reaction sequences involving individual molybdate species. The α-acid was found to form according to a sum of exponentials model [At=θ1+θ2exp(θ3t)+θ4exp(θ5t)] relating absorbance with time. In contrast, the β-acid formed according to a simpler exponential model [At=θ1+θ2exp(θ3t)], which is consistent with pseudo-first-order behaviour with respect to silicate concentration. For the first time in a kinetic study of heteropolymolybdate formation, the effects of changes in molybdate speciation upon the kinetics have been considered in detail. The concentrations of individual molybdate species at pH between 0.5 and 5.0, and total molybdate concentrations up to 0.20 M as molybdenum, have been calculated using equilibrium constants together with an existing computer program. The most interesting result of the study is that the observed α-acid kinetics demand the presence of a third silicon species in addition to the reactant silicate and the α-acid product. At this stage it is not known whether the third species should be another silicate condensation product or a molybdosilicic acid. The general application of the results of this study to silicate analysis is discussed. Methods of non-linear parameter estimation have been used extensively in fitting theoretical models to observed data.


The military etiquettes of Xizhou belongs to the category and ancient etiquette civilization,which not only reflects the characteristics of the transformation of civilization in Xia,Shang,and Zhou dynasties,but also had a profound impact on the Confucianists.In conquering warring,the Confucianists mainly inherited the political and moral elements in the military etiquettes of Xizhou.


In the 6th book of his "Questions on Metaphysics", John Duns Scotus develops a complex study on the truth. To do so, he distinguishes between two modes of truth: a "truth in the thing" and "a truth in the intellect". Here I intend to turn to the first of these notions, reading a short passage of that work in the light of some other texts by the Subtle Doctor – a procedure suggested by those very questions.


The development of new water adsorbents that are hydrothermally stable and can operate more efficiently than existing materials is essential for the advancement of water adsorption-driven chillers. Most of the existing benchmark materials and related systems in this field suffer from clear limitations that must be overcome to meet global requirements for sustainable and green energy production and utilization. Here, we report the energy-efficient water sorption properties of three isostructural metal-organic frameworks (MOFs) based on the simple ligand pyridine-2,4-dicarboxylate, named M-CUK-1 [M3(3-OH)2(2,4-pdc)2] (where M = Co2+, Ni2+ or Mg2+). The highly hydrothermally-stable CUK-1 series feature step-like water adsorption isotherms, relatively high H2O sorption capacities between P/P0 = 0.10─0.25, stable cycling, facile regeneration, and most importantly, benchmark coefficient of performance (COP) values for cooling and heating at low driving temperature. Furthermore, these MOFs are prepared under green hydrothermal conditions in aqueous solutions. Our joint experimental-computational approach revealed that M-CUK-1 integrates several optimal features, resulting in promising materials as advanced water adsorbents for adsorption-driven cooling and heating applications.


Common approaches to evaluate Question Answering (QA) systems consider exclusively the accuracy of the answers. It ignores an essential feature of all the computational procedures: the eciency. In this note, we explore new evaluation measures that take into account, in addition to the accuracy, the eciency, which is incorporated through the magnitude of the answer time of QA systems. In particular, we have developed a family of metrics where the signication of the eciency


The invention discloses a magnetic resonance imaging system. The magnetic resonance imaging system comprises a scanning device and a hospital bed device. The hospital bed device comprises a hospital bed support and a bed plate, the bed plate is capable of moving on the hospital bed support along the length direction, a position determination device is arranged along the length direction of the bed plate, and the position determination device is used for determining a position of a checked portion of a checked person. The position of the checked portion is determined through the position determination device, the bed plate can be controlled and driven to move on the hospital bed support along the length direction, and the checked portion is moved to a set position. A touch screen is arranged on the outer shell of the scanning device, and attitude information of the checked person is conveniently input on spot through the touch screen. The magnetic resonance imaging system not only is convenient, but also reduces the error rate.


The structure of the title compound, C8H7Cl2NO, resembles those of N-(4-chlorophenyl)acetamide, N-2-chloro-(4-methylphenyl)acetamide, N-2-chloro-(4-nitrophenyl)acetamide and other related amides, with similar bond parameters. Molecules are linked into chains through N—H⋯O hydrogen bonding.


A new theorem of existence of solutions for the nonlinear three-point boundary value problem is obtained by using a fixed point theorem due to Krasnoselskii and Zabreiko.


The state of the economy, public confidence, fiscal policy choices as well as administrative efficiency all play an important role in revenue outcomes. Over the last decade, the South African economy has endured prevailing challenges of a weak economic growth, growing public sector wage bill that has exacerbated spending, widening budget deficit, and excessively growing public debt levels among others. Amidst these challenges, the country's revenue collection has continued to perform below expectations, fuelling increased vulnerability. The significance of acquiring and generating more revenue has become evident, especially during the ongoing Coronavirus pandemic and worsening socio-economic indicators which are all but painting gloomy economic prospects. Having an understanding of the nexus between the revenue and macroeconomic objectives of the government is crucial for the formulation of sustainable fiscal policy as well as the realisation of long-term growth and development. The primary objective of this study is therefore to analyse the relationship between government revenue and macroeconomic objectives in the South Africa. The study followed a quantitative research approach using quarterly time series data from 1995Q1 to 2020Q2. The analysis entailed descriptive and econometric analysis. Specifically, an Autoregressive Distributed Lag (ARDL) model was employed to determine the long and short run effects of government revenue and macroeconomic objectives in South Africa. The choice of this estimation model was driven by the consistency in the results it produces while at the same time, allowing the use of data regardless of its stationarity (I(0), I(1) or a combination). In addition, the Toda Yamamoto Non-Granger causality test was employed to determine causality between the selected variables.

Keywords: government revenue; non-tax government revenue; macroeconomic objectives; government spending; South Africa


In this work a new method to prepare Fabry Perot (F P) cavity for optical switch was proposed by filled with unsaturated polyester (UP) resins doped with disperse red 1 (DR 1), and thermal cured in polariza tion process thereafter. Effects of temperature, initiator and DR 1 content on gel and curing time of UP resins were studied. With increasing content of DR1, the gel time is reduced and the curing time was increased. When the content of DR1 was greater than 5%, the resin is no longer suitable for polarization because of long curing time. However, the gel and curing time of the resin can also be reduced by increasing initiator concentration and improving the temperature. After polarization, the optic loss of total F P cavity was 5dB, and electro optic coef ficient r33 was 9pm/V. The maximum decay is 52%, which is lower than the widely studied PMMA/DR1 sys tem. The manufacturing technology for such device was significantly superior to the traditional spin coating method. All of these convinced this novel method to be much fit for making tunable F P cavity for optical switch.


Low back pain related to intervertebral disk (IVD) degeneration has a major socioeconomic impact on our aging society. Therefore, stem cell therapy to activate self-repair of the IVD remains an exciting treatment strategy. In this respect, tissue-specific progenitors may play a crucial role in IVD regeneration, as these cells are perfectly adapted to this niche. Such a rare progenitor cell population residing in the nucleus pulposus (NP) (NP progenitor cells [NPPCs]) was found positive for the angiopoietin-1 receptor (Tie2 + ), and was demonstrated to possess self-renewal capacity and in vitro multipotency. Here, we compared three sorting protocols; that is, fluorescence-activated cell sorting (FACS), magnetic-activated cell sorting (MACS), and a mesh-based label-free cell sorting system (pluriSelect), with respect to cell yield, potential to form colonies (colony-forming units), and in vitro functional differentiation assays for tripotency. The aim of this study was to demonstrate the efficiency of three widespread cell sorting methods for picking rare cells ( < 5%) and how these isolated cells then behave in downstream functional differentiation in adipogenesis, osteogenesis, and chondrogenesis. The cell yields among the isolation methods differed widely, with FACS presenting the highest yield (5.0% – 4.0%), followed by MACS (1.6% – 2.9%) and pluriSelect (1.1% – 1.0%). The number of colonies formed was not significantly different between Tie2 + and Tie2 - NPPCs. Only FACS was able to separate into two functionally different populations that showed trilineage multipotency, while MACS and pluriSelect failed to maintain a clear separation between Tie2 + and Tie2 - populations in differentiation assays. To conclude, the isolation of NPPCs was possible with all three sorting methods, while FACS was the preferred technique for separation of functional Tie2 + cells.


BACKGROUND Juvenile nasopharyngeal angio fi bromas (JNA) are benign, locally destructive lesions that typically occur in adolescent males. These vascular tumors can present numerous clinical and surgical challenges. Complete resection of advanced-stage tumors can be dif fi cult due to the involvement of critical neuro-vascular structures including the orbit, optic nerve, internal carotid artery, cavernous sinus, and middle cranial fossa. When gross total resection cannot be achieved, additional adjuvant therapies may be considered to achieve disease control. Considering the available evidence


Background: Mesenchymal stem cells (MSCs) can be used to treat premature ovarian failure (POF). Different methods have already been applied to detect MSCs in tissues. This study aimed to investigate the quantitative distribution of CM-DiI-labeled human umbilical cord vein MSCs (hUCV-MSCs) in different regions of the ovarian tissue of the cyclophosphamide (CTX)-induced POF in mice. Methods: Adult female C57BL/6 mice (n = 40) were divided into four groups: (1) Mice receiving PBS as control (Ctrl) group; (2) mice receiving hUCV-MSCs intravenously as Ctrl + hUCV-MSCs group; (3) mice receiving CTX intraperitoneally (i.p.) as CTX group; (4) mice receiving CM-DiI-labeled hUCV-MSCs after CTX injection as CTX + hUCV-MSCs group. Histological changes and CM-DiI-labeled hUCV-MSCs distribution were analyzed in the ovarian tissues. Quantitative real-time PCR was performed to detect human mitochondrial cytochrome b (MTCYB) gene in the ovarian tissues of the mice. Results: The mean number of the fluorescent hUCV-MSCs was 20 ± 2.5 (57.1%) in the medulla, 11.3 ± 2.8 (32.2%) in the cortex, and 5.5 ± 1 (15%) in the germinal epithelium of the ovarian tissue (p < 0.05). Moreover, MTCYB gene was detected in the mice ovaries of the CTX + hUCV-MSCs group, but not in other groups. Conclusion: Our findings suggest that the distribution of the transplanted hUCV-MSCs in different regions of the ovarian tissue is not equal, and it is greater in the medulla than the cortex and germinal epithelium. This is the first report of quantitative distribution of MSCs in different regions of ovarian tissue in the POF model.


Elucidating the phase diagram of solid hydrogen is a key objective in condensed matter physics. Several decades ago, it was proposed that at low temperatures and high pressures, solid hydrogen would be a metal with a high superconducting transition temperature. This transition to a metallic state can happen through the closing of the energy gap in the molecular solid or through a transition to an atomic solid. Recent experiments have managed to reach pressures in the range of 400–500 GPa, providing valuable insights. There is strong evidence suggesting that metallization via either of these mechanisms occurs within this pressure range. Computational and experimental studies have identified multiple promising crystal phases, but the limited accuracy of calculations and the limited capabilities of experiments prevent us from determining unequivocally the observed phase or phases. Therefore, it is crucial to investigate the superconducting properties of all the candidate phases. Recently, we reported the superconducting properties of the C2/c-24, Cmca-12, Cmca-4 and I41/amd-2 phases, including anharmonic effects. Here, we report the effects of anisotropy on superconducting properties using Eliashberg theory. Then, we investigate the superconducting properties of deuterium and estimate the size of the isotope effect for each phase. We find that the isotope effect on superconductivity is diminished by anharmonicity in the C2/c-24 and Cmca-12 phases and enlarged in the Cmca-4 and I41/amd-2 phases. Our anharmonic calculations of the C2/c-24 phase of deuterium agree closely with the most recent experiment by Loubeyre et al (2022 Phys. Rev. Lett. 29 035501), indicating that the C2/c-24 phase remains the leading candidate in this pressure range, and has a strong anharmonic character. These characteristics can serve to distinguish among crystal phases in experiment. Furthermore, expanding our understanding of superconductivity in pure hydrogen holds significance in the study of high-Tc hydrides.


In this article a simple index for robot manipulator kinematics design and motion performance is presented. This index is derived by establishing a simple upper bound on the norm of the Jacobian rate of change matrix. Here, the proposed index behaviour is analyzed/tested on a redundant manipulator executing tasks under various scenarios. The results obtained demonstrate that this index compares favorably with other criteria that have been proposed in the literature


Construction companies now use manufactured sand instead of natural river sand in concrete for a day, where the exploration limitation applies to river sand along with the implementation rule. Water, meanwhile, is also the most prevalent aspect of the concrete manufacturing curing process, and it is now scarce for a few days due to a greater rise in human population growth. In contrast to the traditional curing process, self-curing concrete minimizes the use of potable water. In addition to chemical admixture with the mixture, this paper deals with the various studies of fresh and hardened concrete specimens and findings with the self-curing agent mixed with PEG 400 with Fly Ash and GGBFS in different proportions. The results for the various combinations of blended proportions are correlated with the substitution of manufactured sand (M-Sand) with river sand with both ordinary self-curing concrete and mixed self – curing concrete with M30 grade. Attempts have been made to study the properties of blended self – curing concrete with Manufactured Sand.


Using a self-consistent field theory, we examine the thermodynamics and interfacial properties of a homopolymer solution, either close to a single hard surface or confined between two parallel surf...


In power system identification problems using synchrophasor measurements, we frequently encounter the question, whether the model responses match well with actual system responses or not. In power system model validation problems, we need to assess whether the simulated model response matches recorded system behavior. In ringdown analysis, we have to decide whether the model order is sufficient to capture critical system modes in the system measurements, again by comparing model responses with system measurements. In this paper, we propose quantitative indicators founded in rigorous theory to assess such quality of fit problems. Two different indicators, based on frequency domain and time domain formulations respectively, are proposed and are illustrated on power system identification problems.


Pyrolysis represents one of the most convenient technologies for the chemical transformation of waste. The exposure to corrosion products and high temperatures does, however, require chemically resistant construction materials. This study was carried out to analyze the corrosion behavior of 1.4571 (AISI 316Ti) and 1.4305 (AISI 303) stainless steels machined with wire electric discharge machining (WEDM) in a pyrolysis environment. Different machining parameters were used for both materials tested to examine the influence of WEDM machining. The total testing time in the pyrolysis environment was 28 days, with the testing chamber being refilled 12 times. The surface topography was analyzed following the WEDM, cleaning, and corrosion test. The surface morphology and cross-section analyses were carried out using electron microscopy at all three stages of the process. An analysis of the chemical composition of the surfaces was carried out as well as of the pyrolysis environment to which the samples were exposed. It was established that the organic acids found in the pyrolysis chamber did not degrade the tested stainless steels to a meaningful degree. Minor fissures, that is, fine precipitated carbides, were observed on the surface of both the steel types and in their subsurface layer, as well as a significant presence of carbon. This presence was directly connected to the impurities found on the surface after the removal from the test furnace that were probably of a protective or passivation nature.


Background: Undernutrition is a major developmental concern in Uganda, affecting all regions equally. It has been known as the skeleton in the hospital closet because it's overlooked, undiagnosed and untreated by health practitioners. Most studies done on undernutrition had been public facility and community based, as far as we are aware of, none had been private facility based. The study described the burden, patterns and the sociodemographic factors associated with acute undernutrition in hospitalized children on the paediatric ward of KIUTH. Methods: A hospital based cross-sectional descriptive and analytical study was conducted in paediatric ward of Kampala International University Teaching Hospital between January and May 2017. Structured interviews were administered to caregivers of children aged 6 month to 12 years admitted on the ward. Data collected included socio-demographic characteristics, anthropometric measurement. Univariate, bivariate and multivariate logistic regression analysis was done to find the socio-economic factors associated with acute undernutrition. Results: 379 caregiver-children pair were studied. 150(39.6%) 95%CI 34.8-44.6 children were undernourished. Children who stayed with non-biological caregivers were 3.13 at risk of acute undernutrition (aOR 3.13, 95%CI 1.03-9.51, p=0.04), those from Buhweju district were 20.80 times at risk of acute undernutrition (aOR 20.80, 95%CI 2.04-211.60, p=0.01). Children whose caregivers had no level of formal education were 3.07 times at risk of acute undernutrition than those who had primary level of formal education (aOR 3.07, 95%CI1.38-6.83, p=0.006). Likewise those who resided in semi-permanent houses were 3.01 times more likely to have acute undernutrition than those from permanent houses (aOR 3.01, 95%CI1.45-6.25, p=0.003). Conclusion: The proportion of children with undernutrition in this paediatric ward was high. Hospital need to create a nutritional unit. Children with none-biological caregivers, Buhweju and whose caregivers have no formal education, those from semi-permanent houses need to have a more comprehensive nutritional assessment whenever they present to the hospital for care.


In this paper, we report on a systematic investigation of the structure and electrical properties of c-axis oriented Sr1-xLaxCuO2 (SLCO) thin films grown on BaySr1-yTiO3 (BSTO) buffer layers with tunability of the lattice constant from a0=0.3905 nm (y=0, SrTiO3) to a0=0.4000 nm (y=1, BaTiO3), which is favorable to obtain a quantified result of strain effect. We also report on structure and electrical properties improvement of a-axis oriented SLCO thin films on LAO substrates by strain effect control which has been quantificationally studied by c-axis oriented SLCO thin films.


The article explores some legal issues regarding comprehensive trade and mixed agreements of the European Union (EU). The concept of mixed agreements is special to the EU legal order and under strain after the opinion 2/15 of the Court of Justice of the European Union of 16 May 2017, in which the Court defined the exclusive competence of the EU for concluding "EU-only agreements" in the context of the common commercial policy. This led to a split-up of trade agreements of the Union into "EU-only agreements" and mixed agreements on investment issues whereas no change of policy had been established for association agreements to date. Besides creating greater legal certainty, some problems remain regarding the to-be-improved acceptance of EU free trade agreements in the Member States. The analysis focuses on the division of powers between the EU and the Member States and its impact on mixed agreements on a political and legal level. It concludes that "mixity" has not been ended by the jurisprudence of the Court of Justice and can still be seen as a useful tool in the process of negotiating and concluding future comprehensive international trade and association agreements.


A cage segment (1) for a cage of a roller bearing having at least two runs in the circumferential direction of the circumferential webs (2, 3) and at least two connecting webs (4), wherein the peripheral webs (2, 3) and the connecting webs (4) at least one pocket (5) form for accommodating a rolling element (20). In this case, (10 11 12 13,,,), the cage segment (1) eien coupling unit which is configured to connect the retainer segment (1) end face with another retainer segment.


This paper reports the control centres renewal project, that Iberdrola Distribution has undertaken with the company Siemens. Three out of six systems are already in operation and the rest are scheduled for 2005. Project highlights are: the concentration of systems carried out, the unified operator's interface, the renewal of the communications in the field, the advance functionality introduced for the first time in Iberdrola such as electrical applications for medium voltage and the connection to the corporate systems, both for static data -network models, graphics- and for dynamic data such as electrical magnitudes and information related to quality of service.


A response surface model of Listeria monocytogenes' growth rate was built in this study under different temperatures (10 °C, 15 °C, 20 °C, 25 °C and 30 °C) and acid concentrations: citric acid (0–0.4%) and ascorbic acid (0–0.4%); two ingredients which are often used in the food industry as preservatives. Mathematical validation was performed with additional samples at different conditions within the range of the model, obtaining acceptable values of root mean square error (0.0466), standard error of prediction (18.84%), bias factor (1.05) and accuracy factor (1.16). The inhibitory effect on growth was more effective with citric acid than ascorbic acid, possibly due to the major dissociation of citric acid occurring inside microbial cells. The different conditions considered in the model will potentially allow L. monocytogenes' response to be predicted in foods having a similar composition to the chemical and physical factors set out in this paper.


Sediment is widely recognized as a significant pollutant affecting water quality. To assess the impact of land use and management practices upon sediment yield from upland areas, it is necessary to predict erosion and sediment yield as functions of runoff, soil characteristics such as erodibility, and watershed characteristics. The combined runoff -erosion process on upland areas was modeled as overland flow on a plane, with rill and interrill erosion. Solutions to the model were previously obtained for sediment concentration in overland flow, and the combined runoff -erosion model was tested using observed runoff and sediment data. In this paper, the equations are integrated to produce a relationship between volume of runoff and total sediment yield for a given storm. The sediment yield equation is linear in runoff volume, but nonlinear in distance and, thus, watershed area. Parameters of the sediment yield equation include the hydraulic resistance parameter, rill and interrill erodibility terms, and flow depth -detachment coefficient and exponent. INTRODUCTION Sediment is recognized as a significant water pollutant. In addition, sediment transports chemicals, which compounds its effect on water quality. Therefore, it is important to assess the impact of various land use and management practices upon sediment yield from upland areas. To do this, it is necessary to predict erosion and sediment yield as functions of runoff and soil erodibility. Overland flow on a plane, as a function of time and space, can be modeled by the kinematic wave equations. These equations were developed for flow on hydraulically smooth planes, but have been shown to also apply to irregular surfaces (Woolhiser, Hanson, and Kuhlman, 1970). Thus, for geometrically simple watersheds (topographically uniform) such as upland areas without extensive channel systems, the kinematic wave equations for a plane may be used to compute the overland flow hydrograph. As a first approximation, erosion on upland areas can be conceptualized as consisting of rill and interrill erosion. Interrill erosion is assumed due to rainfall impact and associated transport in overland flow. Rill erosion is assumed due to tractive forces and subsequent transport capacity in flow occurring in rills or small channels. These rills or small channels are the irregularities in the overland flow surface. The interrill process is the principal source of soil detachment, and also provides transport of soil particles to the rills where they can be transported in the rill flow. Rill flow is the principal source of transport for soil detached from the interrill areas, but it can also be the source of erosion or a site for sediment deposition if the available sediment load exceeds the rill transport capacity. These concepts are summarized mathematically by Equations 7 and 8. In this paper we derive a simplified sediment yield equation incorporating these concepts. The equation is applied to data from a small watershed, and predicted values are compared with similar values from fitting the Universal Soil Loss Equation (USLE) to determine if the predicted sediment yields are consistent with observations and predictions using a well -known technique. MODEL Kinematic wave equations for overland flow on a plane have been shown to apply to many irregular surfaces (eg., Woolhiser, Hanson, and Kuhlman, (1970)). Such surfaces include topographically simple upland areas on natural watersheds. The one -dimensional kinematic wave equations for a plane are: at 2xR, 1. Contribution of the U.S. Department of Agriculture, Science and Education Administration, Federal Research. 2. The authors are Mathematician and Hydrologist, respectively, Southwest Watershed Research Center, 442 East Seventh Street, Tucson, AZ 85705. 90 (1)


Natural complex adaptive systems show many examples of self-organization and decentralization, such as pattern formation or swarm intelligence. Yet, only multicellular organisms possess the genuine architectural capabilities needed in many engineering application domains, from nanotechnologies to reconfigurable and swarm robotics. Biological development thus offers an important paradigm for a new breed of "evo-devo" computational systems. This work explores the evolutionary potential of an original multi-agent model of artificial embryogeny through differently parametrized simulations. It represents a rare attempt to integrate both self-organization and regulated architectures. Its aim is to illustrate how a developmental system, based on a truly indirect mapping from a modular genotype to a modular phenotype, can facilitate the generation of variations, thus structural innovation.


To tailor the Au@Ag@SiO2 LSPR effect by varying the Ag shell thickness, the Au@Ag@SiO2 core-ultra-thin shell nanoparticles are fabricated and introduced into DSSC for improving light harvesting and decreasing the recombination of photo-carriers. The Au@Ag@SiO2 electrode exhibits a photo-conversion efficiency of 23.42% (486.7 nm, 10 mW cm(-2)).


9:00-9:20 Welcome 9:20-10:00 M. Théra Metric Regularity and Directional Metric 10:00-10:40 M. Volle On Duality for Extended Monotropic Optimization and Application to the Infinite Sum of Functions 10:40-11:10 coffee break 11:10-11:50 G. Crespi Set-optimization and variational analysis: new perspectives and challenges 11:50-12:30 D. Aussel Existence results for variational inequalities: recent advances


Synthesis of SBA-15 mesoporous organosilicas functionalized by phenylamino and gluconamide groups is reported. The organosilicas have been synthesized by co-condensation of proper monomers in the presence of Pluronic P123, and characterized by nitrogen sorption, X-ray diffractometry, elemental analysis, and FTIR spectroscopy to get detailed information about their porous structure, ordering and presence of introduced functional groups. The obtained materials were tested as sorbents of model pharmaceutical (diclofenac) to verify a potential application for removal of pharmaceutical: the observed static sorption capacities were ~50mg/g and ~130mg/g, for phenylamino- and gluconamidefunctionalized samples, respectively, while for pristine sample no adsorption was observed.


Of the international duties that Africa is noted for in the post-Cold War world, participation in peacekeeping is included. Africa is one of the major troop contributors in the numerous efforts to restore peace and order to various conflict areas, particularly those on the African continent. The bulk of African conflicts were either inherited, in the context of the post-colonial crisis that bedevilled the continent, or came during the process of adjustment, consequent to the recession of Cold War politics. The conflict-inducing potential of the simultaneous pursuit of economic reforms, in the form of structural adjustment programmes and democratisation, has also been noted. In addition, elections have proven to be a contentious issue, as the continent's entrenched leadership confront the reality of the periodic renewal of their mandate with the electorate.


Marangoni flow has recently gained much attention for applications in the particle handling in microfluidic channels. This flow is driven by a surface tension gradient along a vapor-liquid interface, which is induced by temperature gradient along the interface. In our previous study, we generated rapid Marangoni vortex flows around a micro bubble using the thermoplasmonic effect of gold nanoparticles under laser illumination [1]. By holding the laser power constant, stable vortex flows developed around the bubble and tracer microparticles dispersed in the fluid were tidily arranged in a circular pattern. Since the induced flow pattern is sensitive to the laser power, we expect that advanced manipulation of micro particles is realized by temporally modulating the laser power. In this presentation, we focus on the clustering of the tracer particles in the temporally controlled thermoplasmonic Marangoni flows.


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Virus-like particle which is composed of several molecules of the viral protein VP1 of JC virus is associated with a cationic polymer, wherein at least one ligand is bound to the cationic polymer, wherein the ligand comprises a target cell-specific group, a labeling group or an effector group.


The image processing method was proposed for white line seam tracking system.The preprocessing for collecting image was realized by homomorphic filter and binarization.The image characteristics edge was extracted by Hough transform and the position of edge was fixed on.Through D/A transform,error about the position was fed back into voltage and Servomotor controlled the rolling of the frame which guaranteed probe realtime tracking seam.Experimental results show that the image processing algorithm has satisfactory detection results and the accuracy of deviation detection si ±1 mm.


Although there has been a considerable body of work on skyline evaluation in multidimensional data with totally ordered attribute domains, there are only a few methods that consider attributes with partially ordered domains. Existing work maps each partially ordered domain to a total order and then adapts algorithms for totally-ordered domains to solve the problem. Nevertheless these methods either use stronger notions of dominance, which generate false positives, or require expensive dominance checks. In this paper, we propose two new methods, which do not have these drawbacks. The first method uses an appropriate mapping of a partial order to a total order, inspired by the lattice theorem and an off-the-shelf skyline algorithm. The second technique uses an appropriate storage and indexing approach, inspired by column stores, which enables efficient verification of whether a pair of objects are incompatible. We demonstrate that both our methods are up to an order of magnitude more efficient than previous work and scale well with different problem parameters, such as complexity of partial orders.


Use of mesenchymal stem cell (MSC) transplantation after myocardial infarction (MI) has been found to have infarct‐limiting effects in numerous experimental and clinical studies. However, recent meta‐analyses of randomized clinical trials on MSC‐based MI therapy have highlighted the need for improving its efficacy. There are two principal approaches for increasing therapeutic effect of MSCs: (i) preventing massive MSC death in ischaemic tissue and (ii) increasing production of cardioreparative growth factors and cytokines with transplanted MSCs. In this review, we aim to integrate our current understanding of genetic approaches that are used for modification of MSCs to enable their improved survival, engraftment, integration, proliferation and differentiation in the ischaemic heart. Genetic modification of MSCs resulting in increased secretion of paracrine factors has also been discussed. In addition, data on MSC preconditioning with physical, chemical and pharmacological factors prior to transplantation are summarized. MSC seeding on three‐dimensional polymeric scaffolds facilitates formation of both intercellular connections and contacts between cells and the extracellular matrix, thereby enhancing cell viability and function. Use of genetic and non‐genetic approaches to modify MSC function holds great promise for regenerative therapy of myocardial ischaemic injury.


It is shown that for the increase of sensibility of X-ray topogram methods to investigate the slantwise cut quartz monocrystal, the external electrostatic field of a certain magnitude should be applied on the sample.

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We have constructed an apparatus for practising elastography in the breast in-vivo. It allows a direct comparison between sonograms and elastograms of a given anatomical site. We will demonstrate that (1) elastograms convey new information, and thus the elastographic appearance of breast tumors is different than their sonographic appearance, and (2) that it is possible to elastographically visualize known breast cancers which are poorly visualized or not visualized at all in sonograms. Due to the sensitivity and low noise in elastography, other potential applications include the visualization of normal, low-contrast tissues such as the internal structures of the kidney and the prostate. Finally, we will discuss some of the theoretical tradeoffs among signal-to-noise ratio, sensitivity, dynamic range and resolution in elastography.


The airline fleet assignment problem addresses the question of how to best assign aircraft fleet types to scheduled flight legs. This paper presents the subnetwork fleet assignment model: a model that employs composite decision variables representing the simultaneous assignment of fleet types to subnetworks of one or more flight legs. The formulation is motivated by the need to better model the revenue side of the objective function. We present a solution method designed to balance revenue approximation and model tractability. Computational results suggest that the approach yields profit improvements over comparable models and that it is computationally tractable for problems of practical size.


The aim of the research is to explore consumer perceptions of masculinity in advertising and determine the effectiveness of these advertising efforts in offering a brand's version of masculinity to men. The researchers ana-lysed consumer comments on the YouTube platform and by applying Nvivo 11 qualitative data analysis software used qualitative content analysis, sentiment analysis, and discourse analysis to understand consumer perceptions of vari-ous brands' efforts in presenting their version of masculinity to consumers. The results showed that masculinity in advertising gets a lot of consumer attention and engagement while the product discourse does not get any noteworthy importance. In addition, the results indicated a correlation between likeability and consumer engagement and the im-portance of the main character and masculinity characteristics displayed in the advertisement for receiving positive consumer feedback.


Transient voltage clamp (TVC) can be used in modern microprocessor power delivery loop to reduce passive decoupling elements. Where to put the TVC and how to control it are the objects of this paper. A microprocessor power supply design without bulk cap on motherboard by using TVC is proposed, which offers adaptive voltage position function and can meet Intel's VRD10.0 specifications.


Systemic sclerosis (SSc) is a chronic connective tissue disease characterised by excessive fibrosis resulting in its most noticeable symptom, the hardened skin. SSc also affects organs including the gastrointestinal (GI) tract, the vascular system, the lungs and the joints. We could previously show that profibrotic cytokines and infiltration of CD4 T lymphocytes are increased in the gastric wall (GW) of SSc patients. In rheumatoid arthritis (RA) we found that certain adipokines have immunomodulatory functions. We therefore analysed localisation of …


This paper introduces the concept of safe operating area (SOA) for the gate dielectric of SiC MOSFETs. The SOA is defined as the stress time-field-temperature space in which the transistor will remain within datasheet specifications and is a more useful parameter than the standardly reported time-to-failure (tfail). Using Weibull statistics, the SOA at 5ppm, 20 Years, T=175°C is ~Vgs =21.5V for onsemi SiC MOSFET products.


Attention is given to the Rayleigh s light scattering modeling. This natural optical phenomenon has been produced in laboratory or classroom by a simple simulation experiment. We propose its modeling, exploring the model-based teaching and learning conception, to improve or facilitate the learner s model-building of the phenomenon and related optical properties involved.


In this paper we analyze intergenerational relationships in the care of women and children during pregnancy, childbirth, and puerperium in Molinos (Salta). Our study is ethnographic and qualitative, focusing on the stories of women from different generations who primarily assume responsibilities and tasks related to domestic care. We compare their domestic and extra-domestic relationships and experiences in order to assess whether they correspond to the cross-age integration model. We find that generational differences in the participation of elderly women in care arise from the changing composition and location of households, conjugal relationships, subsistence activities, and access to health institutions. Despite these differences, older women still provide care and social support during these life stages and become references for decision-making.


Long Term Evolution struggles to provide better Quality of Service (QoS) for multimedia applications in meeting their requirements. To ensure QoS, several quantitative parameters such as delay, jitter, packet loss, bandwidth, etc., must be looked into. There are several problems which occur while enhancing the QoS in resource allocations. Scheduling poses the biggest issue during resource distribution, and it is designed by taking certain parameters both from the user side and from the network side. If a channel is corrupted while processing the resource, the user generates false report and sends back to the base station. Communication is established between user and base station through reference signals. Reference signals are converted into Channel Quality Indicator (CQI) which is fed back to the base station, which then assigns the resource blocks. If the users misbehave by producing false reports, the base station offers the resources wrongly which leads to poor assignment and also to wastage of the resources, such as bandwidth and energy. Consequently, it affects the perfect user to lose their chances of accessing resources because of the depletion of the total energy. The main aim of this paper is to develop a new scheduling algorithm for saving the energy by effectively assigning the resources. By classifying the transmission range and CQI, the proposed algorithm eliminates the imperfect users from the list of available users and uses the energy only for the perfect users, which in turn increases the throughput and enhances the QoS.