Author One: After teaching various grades in small private schools for fourteen years, I was ready to take a professional step forward. I was a successful teacher. I built quality relationships with students as I partnered with their parents. I planned multi-dimensional lessons and strove to engage students in active learning as we pursued academic excellence. But, I was bored. I was not cognitively and emotionally invested in my day-today activities. Having earned my master's degree early in my teaching career, pursuing my doctorate seemed like the next logical step in my professional journey. Author Three: I applied to doctoral programs in order to find something more fulfilling. I had taught preschool through grade 12; public and private schools; regular, gifted, and special education students; as a tutor, knew about how to be an excellent educator.


With the continual enhancing of hardware founction of singlechip, the efficiency of developing singlechip application system is determined by its software in some extent. The character of a kind of simple and efficient singlechip advanced language_Franklin C51 language is introduced. At the same time, its application in developing the program of displaying Chinese characters on LCD is illustrated. It has been successfully used to the portable instrument on detecting the anchoring quality of bolts.


Experiments indicate that turbulent free convection over a horizontal surface (e.g. Rayleigh–Bénard convection) consists of essentially line plumes near the walls, at least for moderately high Rayleigh numbers. Based on this evidence, we propose here a two-dimensional model for near-wall dynamics in Rayleigh–Bénard convection and in general for convection over heated horizontal surfaces. The model proposes a periodic array of steady laminar two-dimensional plumes. A plume is fed on either side by boundary layers on the wall. The results from the model are obtained in two ways. One of the methods uses the similarity solution of Rotem & Classen (1969) for the boundary layer and the similarity solution of Fuji (1963) for the plume. We have derived expressions for mean temperature and temperature and velocity fluctuations near the wall. In the second approach, we compute the two-dimensional flow field in a two-dimensional rectangular open cavity. The number of plumes in the cavity depends on the length of the cavity. The plume spacing is determined from the critical length at which the number of plumes increases by one. The results for average plume spacing and the distribution of r.m.s. temperature and velocity fluctuations are shown to be in acceptable agreement with experimental results.


To conduct the Scientific Outlook on Development and improve the overall arrangement of Socialist course with Chinese characteristics,the social management must be enhanced and innovated.As "the genuine birth-land and stage of the history",Marx's Theory of Civic Society is of great instruction on the establishments of law,social system,and competence.In the meanwhile,the theory also provides an important basis to us to realize the social transformation,from traditional centralized administration conducted by the government to the multiple administration conducted by the whole society.Further more,the theory functions as the guidance for us to improve the governments' administration competence and self-ruling competence of the whole society.


The paper examines the influence of new technologies and media on the book, seen both as printed text and screen structure, as a teaching aid and the constituent part of literary canon. The blurred boundary between the screen and the print clarifies the fact that screen break and page break demand diverse reading strategies: requiring the particular focus, print presents the reader with monovalent information, while screen makes the reader's attention diffused, offering a dazzling array of sources but not the reliability of information. The cultures of print and screen are further divided owing to different attitudes towards new information technologies, defined by Susan Greenfield as webophoria, webophilia and webophobia. While webophobia springs from eternal human fear that illusion might at a certain moment irretrievably erase the truth, webophoria fails to see that the media structure of the Internet changes is irrevocably as well: it has moved from a democratic institution of polilogue towards a commodified dimension of monologue.


English grammar and Indonesian grammar are differentin some ways. One of differences can be seen in constructing sentences based on referring time . The difference of grammatical structure between English and Indonesian which will be learnt especially is tenses for verbal sentences because in verbal sentences the rewill be shown the transformation of verb which does not occur in Indonesian structure. Therefore the researchers using Report Text material in spesifically about students' experience, then There are four students which will be observed by the researchers. the method- research using is the descriptive method or what is usually called the qualitative method.And qualitative data will submitted by observing a hand-writting from the students.


The launching mechanism of the jets of active galactic nuclei is poorly constrained observationally, owing to the large distances to these objects and the very small scales (sub-parsec) involved. To better constrain theoretical models, it is especially important to get information from the region close to the physical base of the jet, where the plasma acceleration takes place. In this paper, we report multi-epoch and multifrequency continuum observations of the z = 2.5 blazar PKS 1830−211 with ALMA, serendipitously coincident with a strong γ-ray flare reported by Fermi-LAT. The blazar is lensed by a foreground z = 0.89 galaxy, with two bright images of the compact core separated by 1′′. Our ALMA observations individually resolve these two images (although not any of their substructures), and we study the change in their relative flux ratio with time (four epochs spread over nearly three times the time delay between the two lensed images) and frequency (between 350 and 1050 GHz, rest frame of the blazar), during the γ-ray flare. In particular, we detect a remarkable frequency-dependent behavior of the flux ratio, which implies the presence of a chromatic structure in the blazar (i.e., a core-shift effect). We rule out the possibility of micro- and milli-lensing effects and propose instead a simple model of plasmon ejection in the blazar's jet to explain the time and frequency variability of the flux ratio. We suggest that PKS 1830−211 is likely to be one of the best sources to probe the activity at the base of a blazar's jet at submillimeter wavelengths, thanks to the peculiar geometry of the system. The implications of the core shift in absorption studies of the foreground z = 0.89 galaxy (e.g., constraints on the cosmological variations of fundamental constants) are discussed.


The present article deals with the study of propagation of plane waves in an isotropic generalized thermoelastic diffusive medium. It is found that, for one dimensional model of isotropic generalized thermoelastic diffusive medium, there exists three kinds of dilatational waves in addition to shear waves which get decoupled from rest of motion and are not affected by thermal and mass diffusion fields. The phase velocity, attenuation coefficient, specific loss and penetration depth of dilatational waves are computed numerically and presented graphically. In addition, the fundamental solution of system of differential equations in the generalized theories of thermoelastic diffusion in case of steady oscillations in terms of elementary functions has been constructed. Some basic properties of the fundamental solution are also established.


Purpose:To evaluate the value of the combination of multi-technique MRI such as DWI,PWI, TDC,MRS in diagnosis of primary brain lymphoma.Materials:Twenty-nine cases of primary brain lymphoma confirmed by clinical and pathological results were enrolled in our study.The signal characteristics of the tumors in conventional MRI,DWI,PWI and MRS which were done before and after treatment were retrospectively analyzed.Results:Primary malignant lymphomas of the brain were shown with equal or slightly lower signal intensity on T_1WI,slightly higher signal intensity on T_2WI.The perifocal edemas were moderate.Most tumors wre shown with homogeneous enhancement after contrasted.The parietal lesions can be shown with "indentation" sign.When the lesion involved the corpus callosum,a "butterfly" sign could be shown.The tumors were mostly homogeneous high intensity signal on DWI,the ADC values of them were much lower than that of the contralateral normal brain parenchyma.PWI showed the tumors were with low rCBV,nearly the same as the normal white matter.The TDC negative ascending branch and descending branch were basically symmetrical.MRS showed the tumors were with significantly higher Cho peak,moderate MAA peak,slightly lower Cr peak,and visible Lip peak.The ratios of Cho/Cr,Lip/Cr,Lac/Cr were significantly increased,the ratios of NAA / Cr was significantly reduced.Conclusion:Conventional MRI of primary malignant lymphoma of the brain has a certain characteristic,through the combination of DWI,PWI, TDC and MRS the performance of their diagnosis can be improved.


1. Calcium channel currents (IBa) were recorded in cultured dorsal root ganglion neurones (DRGs), 24‐32 h after microinjection with 20‐mer phosphorothioate antisense oligonucleotides complementary either to a G alpha o or a G alpha i unique sequence, or with a nonsense sequence. 2. The ability of the GABAB agonist (‐)‐baclofen (50 microM) to inhibit IBa was examined. The maximum peak current was inhibited by 35.3 +/‐ 4.0% (n = 11) in control non‐injected cells, and by 38.1 +/‐ 2.6% (n = 11) and 34.8 +/‐ 4.2% (n = 5) in nonsense‐ and G alpha i oligonucleotide‐injected cells. Following G alpha o oligonucleotide injection, (‐)‐baclofen inhibited IBa by 21.0 +/‐ 3.2% (n = 19). 3. Confocal immunocytochemical localization of G alpha o showed prominent staining at the plasma membrane in control DRGs, and this was also present in G alpha i and nonsense oligonucleotide‐injected cells. The G alpha o staining at the plasma membrane was reduced by 76% in G alpha o oligonucleotide‐injected cells. In contrast, confocal immunocytochemical localization of G alpha i showed immunostaining in the membrane and cytoplasm of control, G alpha o‐ and nonsense‐injected DRGs, whereas this was depleted by 68% in G alpha i oligonucleotide‐injected cells. 4. These results indicate that the GABAB receptor couples to voltage‐sensitive calcium channels via the G protein G(o) and not Gi, and that antisense oligonucleotides can be used to deplete G proteins in DRGs.


This paper presents how the lucid dreaming of a young woman, Kanna, was unpacked in line with the ideas and practices that underlie narrative therapy. It outlines how Kanna's dream was rendered into a metaphor in order to story events and experiences in her life, culminating in the selection of a new support 'Team', and changing what she had come to know as distressing nightmares into 'lucid dreaming', in which she was authorised to shape the stories that she now could tell herself in both her sleep and her waking life.


How should practice managers respond to a patient's request for CCTV footage? Dr Rachel Birch, Medicolegal Consultant at Medical Protection has some advice for practice managers about the legal position with regard to data sharing


Much of the research on women in construction has indicated that they are often not well integrated within their organisations, with their lack of advancement related to exclusionary organisational tactics and discriminatory practices. An inclusive environment, characterised by a culture which supports positive relationships and less stereotypes, should provide an ideal environment for women to utilise their skills effectively, as well as balance their work and family lives. A questionnaire examined the perceptions of a sample of 456 professional women from the Australian construction industry. Inclusion was operationalised through a composite measure using standardised variables and two groups formed using a zero-zero split. Contrary to expectations, comparisons using independent t-tests found the career advancement of the two groups of women were not statistically different. Career satisfaction was significantly higher in the group with high inclusion; however work-family conflict and turnover intent were statistically lower in the same group. These findings indicate inclusion is an important organisational attribute. Some explanations for its lack of effect on women's advancement are discussed.


System Analysis and Design (SAD) is one of the core courses offered in Bachelor's degree programme in Information Technology. However, it is observed that students are not grasping the details of the lessons, and this is affecting their employability and the productivity value in the software development chain. This experience is linked to the presently-used teaching method. In this regard, blended learning model, which improves students' learning experience and reduces underachievement in computer science, is suggested. This study therefore aims to identify the effects of the identified success factors on academic success of SAD. To achieve these objectives, a quantitative research method was employed, involving administration of survey instruments distributed to 151 students, who took SAD as a course in UUM, using simple random sampling, and data collected were analysed with correlation and regression techniques. The study found that students' attitude, students' technology usage level, students' access to technology, students' courseware, curriculum, learning system interface quality, lecture quality, and e-learning system comprehensiveness positively influence students' academic success in SAD.


The estimated annual expenditure on health care is vastly different in the USA (16% of GDP) compared with developing countries (approximately 3% of GDP).1 South Africa is unique in sub-Saharan Africa, where expenditure on health is relatively high and
is estimated to be between 8% and 10%.1 Despite this, there are serious limitations to many aspects of health care delivery based on multiple factors in South Africa. It may be argued that it will take decades before we outlive the injustices imposed on our society
by apartheid. In attempting to offer reasonable and responsible guidance to policy makers and politicians, clinicians and allied health care workers have an obligation to base decisions on objective evidence. Southern African Journal of Critical Care Vol. 24 (1) 2008: pp. 4-6


Pinnacle Systems, located in Dallas, Texas, has stated that software productivity has failed to keep pace with computers. The main reason is that it is still labor-intensive, and previously developed software components are not reused. Market trends continue to be toward greater expectations from computers by users, and interaction with computers on the user's terms. Trends seem to have evolved from:


Institute of Human Genetics and Department of Ophthalmology, University Hospital Erlangen-Nuremberg, Erlangen, Germany, Casey Eye Institute, Department of Ophthalmology, Department of Molecular and Medical Genetics and Department of Neurology, Oregon Health and Sciences University, Portland, OR, USA, Molecular Genetics Laboratory, University Eye Hospital, Tübingen, Germany, Institute of Biochemistry, University Erlangen-Nuremberg, Erlangen, Germany, Dipartimento di Chirurgia, sez. di Oftalmologia, Universitá di Siena, Siena, Italy, University Eye Hospital, Würzburg, Germany


The shock compression response of several THV-alumina particle composites (where THV is a terpolymer of tetrafluoroethylene, hexafluoropropylene, and vinyldiene fluoride) was investigated based on experiments performed in the pressure range of 2–6 GPa. The composites, composed of 25% by volume of either 1, 10, or 100 μm Al2O3, had varying degrees of porosity. The high level of porosity, particularly in the 1 μm Al2O3 composite, obscured determination of any particle size effects. In general, the composites displayed a stiffer shock response than expected, based on the known response of the constituent materials, with the 10 μm Al2O3 composite being slightly stiffer than the 100 μm composite. It is argued that a possible way to describe the stiffer shock compression response is by assigning a higher value for the "effective" Gruneisen parameter γ to the composites. The higher value is consistent with arguments made in the literature that γ for polymers is much higher (by as much as an order of magnitude) t...


The invention relates to efficient multicolor luminous fluorescent crystal material for preparing novel imidazole and silver complex and preparation method of the material. [Ag2(1,4-bis(2-methyl-imidazole-1yl)butane)Br2]n or [Ag2(1,4-bis(2-methyl-imidazole-1yl)butane)I2]n crystal material that is stable and high in luminous efficiency is prepared by means of coordination between 1,4-bis(2-methyl-imidazole-1-yl)butane and silver halide through a mild hydrothermal process. Through X-ray single crystal diffraction, X-ray powder diffraction, infrared absorption spectrum, thermogravimetric curve, excitation spectrum, emission spectrum and the like, it is proved that the luminous crystal material has single crystal characteristics, thermal stability and efficient multicolor luminous characteristic. Two isostructural multicolor luminous fluorescent crystal materials obtained can emit bright light yellow and deep yellow beams when exposed to a handheld ultraviolet lamp at room temperature.


Abstract The new triterpenoid saponin 3-O-[α-L-rhamnopyranosyl-(1→2)-β -D-xylopyranosyl-(1→2)- β -D-glucuronopyranosyl]-3β ,22α-dihydroxyolean-13-en-11-one has been isolated from Ononis spinosa. The new flavonoid glycoside 3-O-[2-O-(E)-p-coumaroyl-β -D-galactopyranosyl]-7-O-β - D-glucopyranosylkaempferol and the new pterocarpan glucoside 3,4-di-O-β -D-glucopyranosyl-4- hydroxymedicarpin have been obtained from Ononis vaginalis. The structures were determined primarily by NMR spectroscopy. The assignment of NMR signals was performed by means of 1H-1H COSY, ROESY, TOCSY, HMQC HMQC-COSY and HMBC experiments.


SAH is a severe disease with a high mortality rate, especially within the first few days following hemorrhage. The treatment of SAH remains one of the major challenges, and a specific therapy is still not available. In addition to abrupt increase in intracranial pressure and simultaneous fall in cerebral blood flow leading to cerebral ischemia, extensive accumulation of subarachnoid hemoglobin and iron may play an important role in early brain injury following SAH. Acute therapy with an iron chelator could be a useful adjunct in the treatment of SAH.


The primary challenge of cloud service providers is finding ways to maintain a high degree of Quality of Service (QoS) in a cost-effective manner to ensure either profitability (for business-based cloud service providers) or cost avoidance (for government cloud service providers). The traditional approach to improving system performance is to upgrade the servers and/or network backbone, an expensive undertaking. The authors used OPNET Modeler to represent distributed system architecture supporting a variety of application services and defined a framework for measuring QoS from the end-user's perspective and discovered that there is no direct relationship between server/network upgrades and overall QoS in distributed systems. This framework can be used as a decision support tool for cloud service providers to optimize the QoS of their systems by choosing upgrade strategies that provide the greatest "bang for the buck."


Due to the Internet era and the background of big data, the express industry in China is developing rapidly. In addition to China Post, private express enterprises in our country are also entering a period of vigorous development. However, private express enterprises are still facing many other problems besides the effectiveness of market economy during development. What's more, the choice of non-market strategy of enterprises has attracted more and more attention, but few people have studied the behavior and image establishment of such enterprises in the face of the public and the media. In the process of using the non-market strategy, the enterprise must deal with the relationship with many stakeholders, in order to help itself to build a unique competitive advantage. Based on the analysis framework established by the enterprise gene theory, this paper makes a deep analysis of social public and media strategy adopted by private express enterprises in China. Taking Shunfeng enterprises as the research object, this paper systematically expounds the concrete manifestations of enterprise genetic mechanism in the development process of private express enterprises, as well as the impact of gene recombination on the choice of non-market strategy for enterprises.


Results: DM1 presented the following abnormalities respect to controls: a significantly lower E wave (64.7±15.4 78.8±13.3 m/sec, p<0.0001) and a comparable A wave (56±11.6 vs 55.6±17 m/sec) with a significantly lower E/A ratio (1.2±0.5 m/sec); a comparable mitral deceleration time contraction and time time, significantly higher than MPI was abnormal 73% and ejection Conclusion: We found significant alterations of myocardial contractility de- tected by MPI in patients with DM1. MPI could be important addition to the echocardiographic evaluation of DM1. Objectives: In our research we aimed to study influence of exercise on dias- tolic and systolic functions of left ventricle (LV) in patients with hypertrophic cardiomyopathy (HCM). Methods: of (LVOT). We used M-mode, two-dimensional and Doppler echocardiography and in 1-1.5 after erect ergo-meter exercise test (EET). Coronary-ventricular fistula (CVF) have been isolated reported in hypertrophic cardiomyopathy and some other patologies. Although their pathogeny and meaning are unclear, it could developed by a coronary steal phenomenon. We report the observation of CVF in Apical Hypertrophic Cardiomyopathy (AHCM). At our knwoledge, it is the first time that a so high prevalence of CVF in AHCM is reported. AHCM Nyquist limit, focus at apical level ). CVF were defined as holodiastolic flow from myocardium to ventricular cavity, differentiating them from intramyocardial coronary flows. Typical AHCM was defined as exclu- sively apical hypertrophy and a thickness relation between apex and posterior wall > 1»5. Mesoapical AHCM was defined if also the mesoventricular but not the basal segments were affected. Results: We studied 13 patient with AHCM, 6 women, aged 64+77, and 6 caracterized as typical. We found CVF in 8 cases (60%). We did not find any relation between CVF and sex, age, cardiovascular risk factors, BMI, medical treatment or any other clinical data. CVF were more often found in patients with typical AHCM (Fischer, p=0.047).CVF were associated to very low ven- tricular volumes (LEDV 62.38+10.9 ml vs 97.6+3.9 ml p<0.001 and LEDSV 23.38+8.8 ml vs 40.6+14.9 ml p=0.022) but not to atrial volume, diastolic pattern, maximum apical thickness or the apex/posterior wall index. Conclusion: Using the appropriate echocardiographic protocol, CVF can be frequently found in the AHCM, mainly in the typical pattern and in those with very low ventricular volumes. The pathogeny and clinical significance of this results should be defined. Objective: Non-compaction of ventricular myocardium (LVNC) is a rare car- diomyopathy characterized by multiple prominent trabeculations with deep interventricular recesses that communicate with the ventricular cavity. It is accompanied by depressed ventricular function, systemic embolism Forty HCM, 21 men, mean age 58+/- 19 43% obstructive, I: 40%, II: 22% and III: 8%. Left ventricular mass (LVM), maximum wall thickness and presence of late gadolinium enhancement (LGE) were assessed by cardiac MR, taking into account their severity, extension and uptake patterns. Maximum dynamic gradient, grade degree of mitral regurgitation (MR) and LV filling pressures (LVFP) estimated by the mitral E (E)/tissue E (E') ratio were assessed by echo-Doppler. Results: LVM and maximum myocardial thickness determined by MR corre-lated acceptably with LVFP (r=0.5; p=0.03). 73% of patients had some de- gree of LGE. LGE grades 3 and 4, extension in more than 6 segments presence of a diffuse pattern were associated with elevated LVFP (p=0.0001). Mild or moderate late enhancement, with an extension lessthan 6 segments present an increase in LVFP. Conclusion: LVM, maximum wall thickness, severity and diffuse late en- hancement pattern were associated with greater deterioration in diastolic function and increase in filling pressures. years Alcohol percutaneous septal ablation (PTSMA) is an effective method of treat- ment in hypertrophic obstructive cardiomyopathy (HOCM), but its long term results are not good recognized. Methods: We present results of alcohol ablation in 18 pts 5 to 9 years post PTSMA in comparison with early, 1 and 3 years results. Assessed parame- thers: peak outflow gradient (LVOTG), left ventricular dimension in systole (LVs) and diastole (LVd), interventricular septum (IVS) and posterior wall (PW) thickness in diastole, left atrium dimension (LA), mitral E and A waves, E/A ratio, isovolumetric relaxation time (IVRT) and deceleration time. We es- timated changes in LV anatomy and contractility, valves function and other new changes. Results: In all patients we observed significant reduction of LVOTG (from 74±40 mm Hg to 13±12 mm Hg). At the end of observation 2 pts had LVOTG >40 mm Hg and 2pts >20 mm Hg. LVs increased after 6 months from 2.2±0.45 cm to 2.9±0.6 cm (p<0.001). LVd from 4.2±0.6 cm to 4.6±0.6 cm (p<0.05) and IVS diminished from 2.4±0.6 cm to 1.5±0.4 cm (p<0.001). PW and LV didn't change significantly. Results after 6 months and in follow-up were similar. Among diastolic function parameters IVRT was shorter after 6 moths and 1 year than before procedure and in follow-up. Mitral insufficiency diminished in most of pts. In 3 pts definite reduction of LVOTG and IVS remodeling ended after 1-3 years. In 1 pts we observed worsening of LV systolic function (progression toward congestive cardiomyopathy?) from 5 years after PTMSA, in other 1 after 7 years - mitral annulus calcification and in 1 significant mitral regurgitation. In 4 pts pacemaker or cardioverter implantation 1 or more years after PTSMA was necessary. In 5 oldest patients we observed new arteriosclerotic plaques in aorta. Conclusion: PTSMA is an effective method in treatment of HOCM in long- term observation. Results in 6 months follow-up are permanent in most of patients. Rhythm and conduction disturbances are still significant problem after suc- cessful PTSMA. Purpose: This study sought to investigate whether conventional and tissue Doppler velocities are predictive of adverse clinical outcomes in patients with with hypertrophic cardiomyopathy (HCM). Methods: Echocardiograms were prospectively obtained in 96 patients with HCM (median age 53). Inclusion criteria were considered: normal sinus rhythm; heart rate <90 beats/min and absence of moderate to severe mitral regurgitation. The end point was sudden cardiac death, ventricular fibrilla- tion/ventricular tachycardia or ICD discharge. Median follow-up was 14.2 months. Results: By univariate analysis, a statistical significant correlation was docu- mented between the end point and tricuspid E velocity (r=0.20, p=0.04), tricuspid A velocity (r=-0.20, p=0.04), transtricuspid E/A ratio (r=0.27, p=0.006), septal mitral Ea (r=-0.28, p=0.006), septal E/Ea ratio (r=0.32, p=0.001) and lateral mitral Aa (r=-0.20, p=0.04). By forward stepwise re- gression analysis, septal E/Ea ratio (R²=0.34, p<0.001) and transtricuspid E/A ratio (R²=0.36, p<0.001) predicted sudden cardiac death, ventricular fibrillation/ventricular tachycardia or ICD discharge. The aim of this study was to evaluate possible correlation between BNP levels, exercise capacity and left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy. Methods: In 19 patients (age 51.1±14.2 years; 11 female) a complete echocardiographic study (with assessement of left ventricular outflow tract obstruction) and cardiopulmonary exercise test (CPX) with assessment of peak VO2 and VE/VCO2 slope (index of excessive exercise ventilation) were performed. In all patients venous blood for BNP analysis was collected after 30 min rest and immediately after exercise. Results: In 10 patients left ventricular outflow tract obstruction was diagnosed. There weren't any significant differences between groups with (HOCM) and without obstruction (HCM) concerning age (44±17 vs 55±8 years), BNP level at rest and after exercise, and peak VO2 (21±4.6 vs 19.5±6 ml/kg/min). There was a trend toward higher VE/VCO2 slope (index of ventilatory re-sponse to exercise) in HOCM. BNP level increased significantly with exer- cise in both groups; HOCM - rest vs exercise - 351±395 vs 505±532 pg/ml; p=0.008 and HCM - rest vs exercise - 381±395 vs 467±450 pg/ml; p=0.005. In the whole investigated group there were significant correlations between BNP level at rest and peak VO2 (r =-0.6; p=0.004) and VE/VCO2slope (r=0.6; p=0.009); and BNP peak exercise level and peak VO2 (r =-0.6; p =0.01) and VE/VCO2 slope (r=0.5; p=0.02). Conclusion: These preliminary observations indicate that BNP level and exercise capacity are not related to left ventricular outflow tract obstruction in HCM. The significant correlations between BNP levels and exercise capacity in patients with HCM, which are similar to that found in heart failure, require further investigation.


Numerous single‐hole and cross‐hole pneumatic injection tests have been conducted in unsaturated fractured tuff at the Apache Leap Research Site (ALRS) near Superior, Arizona. Single‐hole tests have yielded values of air permeability at various locations throughout the tested rock volume on a nominal scale of ∼1 m. Cross‐hole tests have yielded equivalent air permeabilities (and air‐filled porosities) for a rock volume characterized by a length scale of several tens of meters. Cross‐hole tests have also provided high‐resolution tomographic estimates of how air permeability (and air‐filled porosity), defined over grid blocks having a length scale of 1 m, vary throughout a similar rock volume. The results have revealed a highly pronounced scale effect in permeability (and porosity) at the ALRS. We examine the extent to which the permeability scale effect is amenable to interpretation by a recent stochastic scaling theory, which treats the rock as a truncated random fractal.


This study aims to analyze the influence of adversity quotient and emotional intelligence in influencing economic achievement of high school students in Madiun City. This research is a quantitative descriptive research. The research subjects studied were high school students in Madiun City who received economics subjects totaling 302 respondents. Data collection technique using purposive random sampling technique. Research data was taken using a questionnaire which was carried out offline by visiting schools. Data analysis technique using multiple linear regression analysis. The research results obtained are as follows. First, adversity quotient has a positive and significant effect on students' economic achievement. Second, emotional intelligence has a positive and significant effect on students' economic achievement. Third, adversity quotient and emotional intelligence has a positive and significant effect on students' economics learning achievement by 50.2%..


Apollo's oracle gives specific instructions concerning the treatment of the murderer of Laius. Oedipus issues an edict of excommunication and bindshimself under a curse. I wish to examine the relationship between these three pronouncements as they occur initially and as they are used throughout the play. The basis of what I have to say is tentative in that it consists in a particular interpretation of Oedipus' addres, 216 ff., and in the assumption that Sophocles employed a distinction between an edict, that is a secular command of the kingas governing authority, and a curse which, once pronounced, is felt to operate independently. However, both the interpretation and the assumption are farfrom arbitrary, and if they are acceptable the resulting analysis reveals whatmight be called Sophocles' creative use of past episodes. The terms of the oraclegive way to an edict of excommunication, and this in turn, becomes the contentof a curse which initially had a different content.


A mmWave-enabled integrated access backhaul (IAB) network for the 6G cellular Internet of Things (IoT) is necessary to handle the escalating wideband communications needs. A decreased sum rate and low successful transmission probability were the results of the mmWave-enabled IAB network's significant interference problems between access links and differentiated small-cell base stations' backhaul capacities. This article suggests the Q-learn JUP algorithm, which stands for joint user equipment association and power allocation. In order to establish the UA and PA problem, we first investigate how the SBSs-UE association and transmit power are related. Second, using the interference and backhaul burden as the state, UA and PA as the action, and the overall sum rate increment as the reward function of Q-learning, we determine the best joint optimization framework through off-line training. In order to lessen interference and backhaul load, a new backhaul capacity and cautious matching approach utility function has also been designed. Simulation results demonstrate that, in contrast to existing algorithms, the proposed algorithm may vastly enhance the network sum rate and successful transmission probability.


It has become apparent that the move to bring new or improved technological devices into the Federal judiciary is gaining momentum. In the wake of current budgetary restraints, it would be advisable to preface any such move with a complete systems analysis study to make certain that such a move is warranted. This note draws upon the experiences of the state court systems in this area during the last fifteen years as a basis for encouraging these evaluations.


ABSTRACT There is limited data on the implementation of Comprehensive Sexuality Education in Nigerian schools. This study explored In-School adolescents' perspectives on the implementation and utility of the Family Life and HIV/AIDS Education Curriculum, using questionnaires and focus group discussions. Findings reveal that sexuality education in schools is mostly moralistic and cognitive in emphasis, with limited adaptation of interactive methodologies. Inadequate teacher training, teachers' sexual double standards, and limiting curriculum to junior classes were identified as major setbacks. Curriculum expansion, Comprehensive School health programming, continuous teacher training and ensuring that teachers are held accountable for their behaviors are recommended.


Professional development plays a key role in addressing the gap between teacher preparation and standards-based reform; it is a key focus of U.S. efforts to improve education. Much of the professional development that is offered to teachers, however, simply does not meet the challenges of the reform movement (Corcoran, 1995; Darling-Hammond, 1995; Hiebert, 1999; Lieberman, 1996; Little, 1993; Sparks & Loucks-Horsley, 1989).


Overview At all times, system security in electricity markets relies crucially on interactions between demand and supply. While researchers have devoted much attention to dynamics on the supply side most often under inelastic demand assumptions the analysis of price effects on consumer demand still needs to be widened. In the past consumers were exposed to retail prices and wholesale prices were simply not observable. With the establishment of energy exchanges as trading platforms and the growing participation of utilities and industries in auctions the dependency on retail prices might have changed. In this debate, real time pricing could provide incentives for customers to reduce demand in hours where prices peak and, vice versa, shift demand to off peak hours when market demand is low. In theory, we expect a demand smoothing effect on prices in peak hours that increases social welfare. However, it still remains unclear how and to what extend the level of demand responds to changes in prices. We are thus interested in the real-time price elasticity of electricity demand and its evolvement in the past years. Besides being an important information for participants in the market for electricity, the level of price elasticity is especially important for policy makers which are concerned about system security.


A nominally pure Al slab was thermo-mechanically treated to result in a near random texture of 90 m grain size. Subsequent cold rolling with intermediate anneals at 230, 275, and 300°C reduced the Fe solute to near equilibrium compositions below 0.5 ppm atomic. The final cold rolled sheet continuously recrystallized; grain growth of this structure is reported. A grain-growth kinetics mapping was generated, correlating the parameters of Fe-in-Al solubility limit, Fe diffusivities in the grain boundaries and the Al lattice and the activation energies for migration rates.


A waist twisting station includes a base, a rotating unit for waist twisting, and at least one spring to generate resistance force. The rotating unit has a hoop linked with a spring, which can be pushed away by user's body movement. The inside layer of the hoop has a row of massage balls so that the body movement can exercise the waist and lags as well as receive body massage at the same time to accelerate calorie burning. In addition to the waist twisting hoop, a handle bar with or without spring connected to the base can give user a unique whole body exercise experience.


A 76-year-old man was admitted to our hospital for one month of progressive word finding problems. He was diagnosed with Waldenstr€ om macroglobulinemia (WM) two years prior when he presented with fatigue and anemia. The patient carried the MYD88 L265P gene mutation. In the past year, he had developed pancytopenia, elevated serum viscosity, enlarged intra-abdominal lymph nodes, and bilateral pleural effusions. Treatment with monthly infusions of bendamustine and rituximab had been initiated four months before presentation. His absolute lymphocyte count was 1.51 k/uL at the start of therapy, 0.92 k/uL at Cycle 2, 0.75 k/uL at Cycle 3, 1.64 k/uL at Cycle 4, and 1.88 k/uL at four week follow-up after Cycle 4. His counts reached a nadir of 0.24 k/uL midway through the treatment regimen. The patient's word finding difficulties suggest a lesion in the central nervous system (CNS), specifically in the peri-sylvian region of the left hemisphere, which includes Broca's area (the center for language expression) anteriorly, Wernicke's area (the center for language comprehension) posteriorly, and subcortical white matter fibers (arcuate fasciculus) that connect these two regions. The history of WM, and current immunocompromised state due to the disease itself and chemotherapy, raise a broad differential for his neurological symptoms. The most concerning etiologies include arterial or venous occlusion and cerebral infarction due to serum hyperviscosity, cerebral or meningeal inflammation from WM (Bing-Neel syndrome [BNS]), paraneoplastic or other autoimmune encephalitis, or opportunistic infection. On examination, he was alert and interactive with mild bradyphrenia. He had impaired fluency with frequent phonemic and semantic paraphasic errors. He could follow simple commands and repeat short but not longer or more complex sentences. He had right-sided brachiofacial weakness. The remainder of his neurological exam was normal. Abnormal laboratory studies included hemoglobin 11.2 g/dL, white blood cells (WBC) 2.09 k/uL with absolute neutrophil count 0.38 k/uL, absolute lymphocyte count 0.54 k/uL and platelet count 142 3 10/L. Serum protein electrophoresis demonstrated a monoclonal spike in the gamma region of 0.34 g/dL and immunofixation confirmed a monoclonal IgM Kappa paraprotein. Serum IgM level was 379 mg/dL. The patient was in a partial response after 4 cycles of bendamustine and rituximab. The examination supports a mixed aphasia with elements of nonfluency and impaired comprehension that localizes to the left frontal and temporal lobes. The presence of pancytopenia and concurrent immunosuppressive therapy places this patient at elevated risk for progressive multifocal leukoencephalopathy (PML), toxoplasmosis, and primary CNS lymphoma. Furthermore, one should consider CNS abscesses or meningo-encephalitides from fungal (Aspergillus, Cryptococcus), viral (HSV, CMV, VZV) or mycobacterial species. BNS has been described in patients who are responding to therapy for systemic WM [1]. Therefore, the patient's response to therapy does not exclude the diagnosis of BNS. With a serum IgM level less than 3,000 mg/dL, hyperviscosity is unlikely. The next step in clarifying the diagnosis is a brain MRI with gadolinium. MRI showed multifocal well-demarcated nearly confluent areas of abnormal T2 hyperintensity, predominantly in the subcortical white matter of the left frontal, temporal, parietal, and right frontal lobes (Fig. 1A,B). A dominant lesion in the left anterior frontal sub-cortical white matter was edematous and exerted mass effect on adjacent structures. There was modest reduced diffusivity at the periphery of the left frontal lesion (Fig. 1C). There was no abnormal enhancement of this lesion on post-contrast images. As part of staging for WM, the patient underwent a full body positron emission tomography (PET) scan that showed no systemic 18F-FDG-avid lesions. The left frontal lobe lesion showed reduced 18F-FDG uptake (Fig. 1D). The radiographic findings support a multifocal process with a tumefactive lesion in the left frontal lobe. The juxtacortical white matter hyperintensities on T2-weighted images are consistent with an infiltrative condition. The absence of prominent reduced diffusivity makes primary CNS lymphoma or abscess less likely. Furthermore, the absence of contrast enhancement and hypometabolism on PET scan are atypical for high-grade primary or metastatic brain neoplasms. The radiological differential includes PML or BNS. PML produces a pattern of demyelination that is predominantly localized to the frontal and parieto-occipital lobes. Lesions are generally hypointense and


Abstract Background: Sphenoid wing meningiomas among difficult surgery tumours due to involvement of important structures like optic nerve, cavernous sinus or carotid artery. Objective: to evaluate outcome and prognostic factors in patients with medial sphenoid wing meningiomas after microsurgery in a series of 47 patients with medial sphenoid wing meningioma. Method: This paper includes analysis of 47 patients & their data who underwent surgical management for meningiomas involving the medial sphenoid wing in the period between Jan 2008 and February 2016 at Mansoura university hospital. Results: The most of patients were suffering from visual impairment (59.6%), followed by headaches (38.2%). Total tumor resection were achieved in 23 cases, incomplete in 19 cases and partial resection in 5 cases. Visual acuity improved or stable in 57.4% of the patients. Preoperative neurological deficit remains unchanged postoperative in 35 cases while improved in 4 cases. 8 cases developed permanent 3rd Nerve palsy. Tumor recurrence was in 7 patients. Conclusion: There are many factors influence the prognosis of inner sphenoid wing meningioma including the extent of surgical resection, cavernous sinus invasion, present or absent of peritumoral edema, vascularity of the tumor, size of the tumor, presence or absence of arachnoid plane between the tumor and surrounding neurovascular structures and preoperative neurological condition


For women, shoes are so important tools as to signify the completion of the fashion. Thus, if they were prohibited from wearing high heels, it could imply they should give up the fashion. This study investigates the influence of the shape of shoe toes on human feet. By using the insole-type foot pressure measurement system, the sole of a foot is divided into ten zones, with one pair of indoor shoes and 5-centimeter-high pumps of three different kinds of toe shapes(square type, round type, and pointed type), and then the access area, maximum force, and maximum pressure of each zone are measured. The experiments showed that the shoes with pointed type have large access area with relatively narrow area of toe bones, which mean high pressure. In addition, it is observed that the larger forefoot pressure or force results in the decrease in the advancement function of big toes. The concern is also confirmed that the abduction of big toes caused the collapse of arch in the case of a flatfoot. In cases of square and round type, the big toe's advancement function was more prominent in the former than in the latter, which corresponds to the idea of more effective shape of toes for walking. According to the above results, the best shape of shoe toe for women's foot health is considered to be in the order of square type, round type, and pointed type.


Plant bugs of the family Miridae are serious pests of seed, fruit, and nursery crops throughout the world. The genus Lygus Hahn has at least 9 species of major importance to agriculture in North America, Europe, and Asia (Kelton 1975). The bulk of this review will deal with these species, but where appropriate, reference will be made to the following additional species in the family Miridae: alfalfa plant bug, Adelophocoris lineolatus (Goeze); cotton fleahopper, Pseudatomoscelis seriatus (Reuter); Lygocoris pabulinus (L.), and Taylorilygus vosseleri Poppius. Whenever possible, papers dealing with crop resistance relationships of lygus bugs and related mirids are used for discussion.


This paper presents the establishment of the Agent-based Dynamic Model for Pedestrian counter flow (ADMP). It was shown that a rule set of pedestrian behaviors and its combination with a dynamic model for pedestrian flow was capable of effectively capturing the crowd flow rules of pedestrians using agent-based technology. Two digital tests of bottlenecks of evacuation passage in counter flow are presented, in which 200 and 300 pedestrians were stochastically distributed in a space measuring 40000 x 10000 (mm). Crowd behavior phenomena, such as arching, jamming, lane forming, and oscillating could be observed after certain critical points. From a comparison of the two digital tests, it could be seen that, with an increase in pedestrian density, the counter flow became more and more disorderly, and the two different directions of flow struggled more excitedly as a result. It illustrated that the ADMP was efficient in the simulation of pedestrian flow and is a useful tool for fire safety research and management.


Declining mastery of the English language is a cause of great concern and consternation in Malaysia, particularly in the education domain. OUM seeks to address issue of learners' English language readiness by making four basic level English based courses compulsory to all undergraduate students. This paper looks specifically at the grammar of the language used by OUM learners in two of the courses mentioned above to ascertain their mastery, or lack of it, of a specific grammatical construction, the Perfective HAVE in present perfect sentences based on a corpus derived from their coursework. This paper analyses learners' use of the perfective HAVE in the present perfect tense a corpus of learner submitted assignment papers. This syntactical construction is chosen because it is generally regarded by learners as one of the harder tenses to master. The findings will show that while there are indeed issues the learners' mastery of the said construction, they are not entirely unable to use the construction.


Molecular rotors have emerged as versatile probes for microscopic viscosity in live cells, however, the exclusive localisation of rotors in the plasma membrane has remained elusive. We report the synthesis, spectroscopic characterisation and live cell imaging of a new BODIPY-based molecular rotor suitable for mapping viscosity in the cell plasma membrane.


Sir: We read with interest the letter by Scott et al. where they found no significant difference in HIV test uptake before and after the introduction of the opt-out method (74.8% before and 74% after opt-out method). They explained this to the already increased uptake before the opt-out testing. However, our audit shows that despite an initial high HIV uptake rate, there was a significant rise following the opt-out policy. The UK National Guidelines on HIV testing June 2006 recommends that all new patients attending genitourinary (GU) medicine clinics should be offered HIV testing and an information leaflet should be used to increase HIV uptake. The National Strategy for Sexual Health and HIV set its target for reducing undiagnosed HIV in genitourinary medicine clinics by increasing the HIV testing uptake to 40% by the end of 2004 and to 60% by the end of 2007. We introduced an opt-out system for HIV testing in August 2006, replacing the previous policy where clinicians recommended an HIV test to patients. All patients were instructed by the reception staff to read the patient information leaflet on HIV testing while waiting to see a clinician. Posters were displayed in the waiting area informing that blood would routinely be tested for HIV along with syphilis. During consultation, the above information was again reinforced. A retrospective case-note audit before the introduction of the opt-out policy between April and June 2006 showed the HIV uptake rate to be 66% (418 of the 633 new and re-registered patients) demonstrating that we had already exceeded the target. Individual clinician HIV uptake rate too was looked at (see Figure 1). Individual feedback and ways to increase the uptake rate was discussed following the audit. Our second audit between September and November 2006 following introduction of opt-out policy showed HIV test uptake rate to be significantly increased to 80.2% (651 of 812 new and re-registered patients, odds ratio [OR]1⁄4 2.08). No statistically significant differences were found between age and gender in the two groups. This increase in HIV test uptake rate was in keeping with other studies where the increase in uptake was from 50% to 62% and from 35% to 65% following leaflet and opt-out method introduction, respectively. We had conducted our audit a month after the intervention when staff were more used to the advice and perhaps the data is more reflective of the change in practice in contrast to Scott et al., where the audit was done immediately after the introduction of the opt-out policy. There was an increase in the uptake rate of HIV testing by all clinicians in the second audit except in one (opt-out policy, Figure 1), in whom the majority of patients (60%) who had declined the test were re-registered patients who had had a recent HIV negative test. The increase in HIV test uptake rate was marginal in those who already had a high uptake rate at the initial audit as compared with those individuals with a lower uptake rate. This highlights that looking at individual uptake rates may help to improve the overall uptake rate by addressing issues individually. In addition, in the audit following opt-out policy we also looked at the reasons for not having the HIV test (see Table 1). Higher number of female patients (129, 80.1%) did not have the HIV test as compared with the males (32, 19.9%), (P1⁄4o0.001, w test). Age was not significantly associated with gender and HIV test uptake rate. To summarize, opt-out policy with introduction of a leaflet has led to an increase in the HIV uptake rate in our audit. Auditing individual clinicians' uptake rate may help to increase the uptake rate in those with low uptake rate by giving individual feedback and discussing ways to improve. Female patients should be encouraged further for testing. Given that a quarter of HIV-positive individuals are unaware of their HIV status both in the UK and the USA, the policy of routine HIV testing in all health-care settings as recently been introduced in the USAmay be something which UK may have to consider.


The central argument of this chapter is that statutory Parental Leave policy must be conceptualised within a broader framework of care-work policies and cultural ideas over care tasks. We propose a model based on structural and cultural dimensions. The former includes leaves (Maternity, Paternity, Parental), ECEC services, the relationship or gap between leave and ECEC entitlements, occupational welfare, and family structures (e.g. proportion of children living with two parents); the latter include levels of gender inequality and intergenerational solidarity orientation. Considering these six dimensions we focus on four countries, namely Germany, Italy, Sweden and the UK, representing well-established welfare regime models. Our analysis highlights how Germany and Sweden seem more similar than might be expected in light of established welfare regime models, while Italy and the UK are in contrast somewhat similar in terms of their Parental Leave models, whilst showing many differences in relation to other social actors involved in providing welfare goods.


The objective was to optimize the topical diagnosis of the inflammatory process in the kidney and bladder in women with urolithiasis Methods and materials. Examined were 31 women aged 25 to 65 y. o., hospitalized for exacerbation of chronic cystitis with urolithiasis. The comparison group consisted of 15 healthy people without a history of urological diseases. In urine taken the level of pro-inflammatory interleukin 8 (IL 8) was determined by enzyme-linked immunosorbent assay. Results. With an isolated exacerbation of chronic cystitis in the urine taken from the ureters, the concentration of IL 8 ((39±7.6) pg/ml) did not go beyond the normal indicators ((35±7) pg/ml), while the content of this cytokine in the bladder exceeded the norm by at least 3 times ((120±3.5) pg/ml). With a combination of exacerbations of inflammation in the bladder and kidneys, the concentration of IL 8 in the bladder was about 10 times higher than the control values ((350±27) pg/ml), and in the ureter from the affected side, no less than 8 times ((280±16) pg/ml). Conclusions. A comparison of the content of IL 8 in urine from organs (kidneys, bladder) that are supposedly affected by the inflammatory process makes it possible to clarify the localization of the focus of inflammation in the urinary system. the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.


This paper presents the heat transfer and friction coefficient correlations for triangular plain fin surfaces of plate fin compact heat exchanger. It will be prohibitively expensive and time consuming to fabricate heat exchanger cores and conduct experiments over reasonable ranges of all the geometric variables. In contrast, it is relatively easy and cost effective to carry out a parametric study through numerical simulation and derive acceptable correlations for use in industry. A numerical model has been developed for the triangular plain fin of plate fin heat exchanger. The CFD analysis is carried out using FLUENT 12.1, Colburn factor j and fanning friction factor f are calculated for different Reynolds numbers. These values are compared with the available literature data of j and f factors. The correlations have been expressed in terms of two separate equations over the low and high Re regions along with dimensionless geometric parameters.


This paper introduces the social and cultural backgrounds of temple, garden, atrium and other architectural elements and points out that the environment is comprehensive reflection of culture, while the formation of any culture has its historical and regional origins.


International Treatment Guidelines Pages 1-3 Meta Analyses Pages 3-4 Randomized Controlled Trauma Studies Pages 5-12 Non-Randomized Trauma Studies Pages 12-16 Adaptive Information Processing and EMDR Procedures Pages Pages 16-24 Mechanism of Action Pages 24-29 Randoized Studies of Hypotheses Regarding Eye Movements Pages 29-33 Additional Neurobiological Evaluations Pages 33-35 Combat Veteran Treatment Pages 35-38


The aim of this work was to obtain, by water extraction, antioxidant dietary fiber from orange juice byproducts. Extractions were performed to orange pomace powder (OPP) varying temperature (55, 65, 75°C) and time (30, 45, 60 min). Two fractions (sediment and supernatant) were obtained from the water extractions and extractable polyphenolic content, antioxidant capacity, total carotenoid content (TCC), and bioaccessibility were determined. Results showed that at 75°C and 45 min the best combination of antioxidant capacity for both fractions is obtained. Under this condition, the sediment is a potential source of antioxidant dietary fiber. Supernatant is rich in bioaccessible polyphenols, associated to soluble fiber as majority component of dietary fiber. Moreover, the water extraction increased the bioaccessibility of polyphenols and carotenoids contained in the OPP. Therefore, both fractions are a potential source of functional food ingredients and orange juice byproducts were entirely revalued. PRACTICAL APPLICATIONS: The present study suggests an extraction method for orange juice byproducts. Following the principles of green extraction, the technique proposed consists of a water extraction (free of solvents), does not produce waste and is of easy industrial application. As a result, two potential food ingredients with different functional and technological properties are obtained. Therefore, orange juice byproducts are completely revalued and a solution for the management of these byproducts is presented. In addition, the two functional ingredients obtained in this study are a step in the right direction for the development of new functional food formulations.


We recently reported that, depending on its concentration, urate is either a pro- or an antioxidant in Cu(2+)-induced low-density lipoprotein (LDL) oxidation. We also previously demonstrated an antioxidant synergy between urate and some flavonoids in the Cu(2+)-induced oxidation of diluted serum. As a result, the effect of the flavonoid quercetin on the Cu(2+)-induced oxidation of isolated LDL has been studied either in the presence or absence of urate. We demonstrate that, like urate, quercetin alone, at low concentration, exhibits a pro-oxidant activity. The pro-oxidant behavior depends on the Cu(2+) concentration but it is not observed at high Cu(2+) concentration. When compared with urate, the switch between the pro- and the antioxidant activities occurs at much lower quercetin concentrations. As for urate, the pro-oxidant character of quercetin is related to its ability to reduce Cu(2+) with the formation of semioxidized quercetin and Cu(+) with an expected yield larger than that obtained with urate owing to a more favorable redox potential. It is also shown that the pro-oxidant activity of urate can be inhibited by quercetin. An electron transfer between quercetin and semioxidized urate leading to the repair of urate could account for this observation as suggested by recently published pulse radiolysis data. It is anticipated that the interactions between quercetin-Cu(2+)-LDL and urate, which are tightly controlled by their respective concentration, determine the balance between the pro- and antioxidant behaviors. Moreover, as already observed with other antioxidants, it is demonstrated that quercetin alone behaves as a pro-oxidant towards preoxidized LDL.


We review basic properties of the Nakayama functor for coalgebras and introduce a number of applications to tensor categories. We also give equivalent conditions for a coquasi-bialgebra with preantipode to admit a non-zero cointegral.


Often a carefully chosen data structure will allow the most efficient algorithm to be used. A well-designed data structure allows us to apply variety of critical operations by the few resources, both execution time and memory space. In this paper I introduce the concept of metagraph as a new model of data structure. Metagraph is graphical hierarchical data structure in which every node is a set having one or more elements. It has all the properties of graphs. In a metagraph, there is set to set mapping in place of node to node as in a conventional graph structure. In a metagraph as data structures data will be stored inside the computer memory either in the form of adjacency matrix or in adjacency list so that it can be used efficiently.


A mixture of latex and drilling mud clay controls lost circulation in large carbonate fractures by coagulating when it mixes with the formation fluids. The mixture forms large aggregates capable of plugging large formation fractures and is not prone to being washed out by formation water. The Scientific Research Institute of Drilling Techniques in Moscow (Vniibt) has developed a special lost circulation mixture combining a latex base and clay drilling mud for use in plugging these fractures. Mud powders of bentonite and calcium clays can be used to prepare the clay-latex mixture (GPC). The latex is mixed with drilling mud made from bentonite clay powder and is pumped to the lost circulation zone where it coagulates by reacting with the calcium ions in the formation water. The latex used to prepare GPC must be compatible with the mud being used. After coagulation, GPC changes to a rubber mixture. In the Tataria oil region, one of the drilling enterprises used GPC in 23 wells, with positive results in 20 of the wells. The bentonite powder base GPC mixture remains easily pumpable until the end of the operation. The mixture`s plastic strength increases over time as it is pumped into the lostmore » circulation zone. This type of mixture is typically used to control lost circulation at depths greater than 1,000--1,500 m. GPC based on drilling mud made from calcium clay is used at shallower depths. For GPC pumped into a borehole, the latex/clay drilling mud ratio is typically between 1:1 and 1:2.« less


A practical method for the design of artificial neural networks (ANN) for behavioral modeling of various devices is presented. The approach has been applied to the modeling of micro-flow sensors and MOS transistors. It is shown that the ANN based behavioral models are accurate and computationally efficient.


The localization of the auxin receptor relevant to the control of elongation growth is still a matter of controversy. Auxin-induced elongation of maize coleoptile segments was measured by means of a high resolution auxanometer. When indole-3-acetic acid (IAA) was removed from the bathing solution, a rapid cessation of auxin-induced elongation was detected. This decline was delayed when the auxin efflux carrier was blocked by the phytotropins naphthylphthalamic acid (NPA) and pyrenoylbenzoic acid (PBA) or by triiodobenzoic acid (TIBA). The IAA concentration in NPA-pretreated segments was 2–3 times higher than in NPA-free controls 35 min after the removal of IAA in the bathing medium.

A similar rapid drop of growth after removal of auxin was observed for the rapidly-transported synthetic auxin, naphthaleneacetic acid (NAA). When the auxin efflux was blocked, growth induced by NAA was sustained much longer than IAA-stimulated elongation.

In comparison with NAA, the synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D) is known to be excreted very slowly by the efflux carrier. 2,4-D-induced growth remained at a stimulated level when the auxin was washed off, even in the absence of any auxin efflux inhibitor. We conclude from these results that the presence of intracellular auxin is a necessary and sufficient condition for sustained auxin-induced elongation growth, at least for the phases during the 2 h after its application. Consequently, we postulate the existence of an intracellular auxin receptor relevant to the control of growth.


Letter from M. A. Atkinson, Sales Manager American Airlines, to Amon Carter regarding invitations for Fort Worth cocktail party at National Airports Advisory Board Meeting. Includes invitation list.


Only two (5.5%) of 36 possible or known carriers of the gene in Duchenne dystrophy showed increased lactate dehydrogenase isoenzyme 5 (LDH-5) (U/L) in serum, while creatine kinase (CK) was increased in ten (27.8%). LDH-5 and CK did not increase simultaneously; in all five known carriers CK activity was abnormal but LDH-5 was normal. In muscle biopsy, LDH-5 was reduced in patients with Duchenne dystrophy (25.6 ± 11.5% of total, mean ± SD; controls 59.9 ± 10.3%; p ≤ 0.01) and in two of nine possible carriers, but as a group the carriers did not differ from controls: (49.9 ± 12.1%; p > 0.05).


The environment geological conditions of the Zhuyin reservoir is more complex.Though analysis of engineering geological conditions,such as landforms,and formation lithology and so on,the leakage passage of the reservoir and connectivity conditions are evaluated.Forecast the reservoir seepage development degree is medium,the hazard risk is medium,and the hazard extent is small.


Analysing the IOBC authenticated encryption mode.- A Chosen IV Related Key Attack on Grain.- Cryptanalysis of Helix and Phelix Revisited.- Toward Separating the Strong Adaptive Pseudo-Freeness from the Strong RSA Assumption.- Minkowski sum based lattice construction for multivariate simultaneous.- Coppersmith's technique and applications to RSA.- Lattices and security proofs.- Adaptive Precision Floating Point LL.- Better Lattice Constructions for Solving Multivariate Linear Equations Modulo Unknown Divisors.- Key-Dependent Message Chosen-Ciphertext Security of the Cramer-Shoup Cryptosystem.- Black-Box Separations and their Adaptability to the Non-Uniform Model.- Injective Encodings to Elliptic Curves.- Membership Encryption and Its Applications.- Towards Privacy Preserving Mobile Internet Communications.- Count-min sketches for estimating password frequency with Hamming Distance.- Secret sharing.- A rational secret sharing protocol with unconditional security in the synchronous setting.- Secret Sharing Schemes with Conversion Protocol to Achieve Short Share-Size and Extendibility to Multiparty Computation.


The purpose of this study was to evaluate the comparative efficacy and tolerability of sertraline and fluoxetine in the treatment of obsessivecompulsive disorder (OCD). Outpatients meeting DSM-IV criteria for OCD, with a Yale-Brown Obsessive-Compulsive (Y-BOCS) total score ≥ 17, an NIMH Global Obsessive-Compulsive (NIMH-OC) scale score ≥ 7, and a CGI-Severity score ≥ 4 were randomized to 24 weeks of double-blind treatment with sertraline (N = 77) or fluoxetine (N = 73). Primary efficacy measures consisted of the Y-BOCS, the NIMH-OC scale, and the CGI-Severity (CGI-S) and Improvement (CGI-I) scales. Equivalent and significant (p < 0.001) improvement was found at week 24 in Y-BOCS and NIMH-OC scale scores for sertraline and fluoxetine. After 12 weeks, 49.2% of patients on sertraline were rated on the CGI-S scale as being mildly ill or not ill compared to 24.6% on fluoxetine (p < 0.01). A Cox analysis found patients on sertraline to have a statistically nonsignificant 42% greater likelihood of achieving a response by week 12 (CGI-I, much or very much improved; 95% CI, 0.85, 2.38;p = 0.18). Sertraline treatment also resulted in a higher proportion of remissions than fluoxetine (defined as a CGI-I ≤ 2 and a Y-BOCS score ≤ 11), both at week 12 (20% vs. 8%; χ2, 3.95;df 1;p = 0.047) and week 24 (36% vs. 22%; χ2, 3.18;df, 1;p = 0.075). Both medications were welltolerated and demonstrated significant efficacy in the treatment of outpatients with moderate to severe OCD with the subjects treated with sertraline showing a greater likelihood of remission as well as an earlier improvement on some but not all efficacy measures


The following recommendations are based on expert opinions of an international multidisciplinary panel endorsed by the "European Federation of National Associations of Orthopaedics and Traumatology" (EFORT), the "European Hip Society" (EHS), the German "Arbeitsgemeinschaft Endoprothetik" (AE) and the "Deutsche Arthrosehilfe" (DAH)


Social media analysis constitutes a scientific field that is rapidly gaining ground due to its numerous research challenges and practical applications, as well as the unprecedented availability of data in real time. Several of these applications have significant social and economical impact, such as journalism, crisis management, advertising, etc. However, two issues regarding these applications have to be confronted. The first one is the financial cost. Despite the abundance of information, it typically comes at a premium price, and only a fraction is provided free of charge. For example, Twitter, a predominant social media online service, grants researchers and practitioners free access to only a small proportion (1%) of its publicly available stream. The second issue is the computational cost. Even when the full stream is available, off the shelf approaches are unable to operate in such settings due to the real-time computational demands. Consequently, real world applications as well as research efforts that exploit such information are limited to utilizing only a subset of the available data. In this paper, we are interested in evaluating the extent to which analytical processes are affected by the aforementioned limitation. In particular, we apply a plethora of analysis processes on two subsets of Twitter public data, obtained through the service's sampling API's. The first one is the default 1% sample, whereas the second is the Garden hose sample that our research group has access to, returning 10% of all public data. We extensively evaluate their relative performance in numerous scenarios.


Early childhood education and care is currently experiencing unprecedented policy interest and expansion. This policy and practice landscape requires new forms of adaptive leadership, new spaces for production of the knowledge necessary for this changing context, and tools that can support the development of leadership qualities. This paper examines the potential of practitioner research to produce contextually relevant knowledge and to develop leadership capacity. Our findings show that collaborative practitioner research groups provide a relatively safe environment for the sharing of dilemmas and critical reflections. The practitioners who participated in this research wanted access to narratives of change in typically resourced early childhood contexts as well as in the more highly resourced settings that are more often reflected in academic research and literature. This suggests there is a need for much more of this work to be publicly available. These groups can generate the courage required to open practice based research to public critique. This, we argue is an important element of activist leadership. Collaborative practitioner research opens up the possibility for practitioners to position themselves as knowledge producers and to revitalize the knowledge base that informs teacher education in the academy. In supporting this move, academics need to position themselves as resource gathers and co-learners thus opening a third space for knowledge production. The challenges for the profession are how to fund and effectively disseminate collaborative practitioner research and how to draw it into dialogue with other forms of research.


Aryl and vinyl sulfides have attracted much attention from medical and organic chemists because they are prevalent in natural or bioactive molecules and other potential functional organic materials. Therefore, considerable efforts have been made for the construction of aryl and vinyl sulfides, among them transition metal-free direct C — H bond sulfenylation has developed rapidly and became an efficient and eco-friendly synthetic protocol. In recent years, many excellent research achievements were presented and a range of sulfenylated alkenes and arenes were synthesized using this strategy. The recent five-year progress in direct sulfenylation of C — H bond on alkenes and arenes under transition metal-free conditions is re-viewed and the corresponding reaction mechanisms are discussed.


In this paper, linear antenna-array with logarithmically increasing inter-element spacing and non-uniform excitation amplitudes or weights has been investigated for beamwidth (BW), side lobe level (SLL) and directivity (D). This non-uniform linear array has been compared with uniform and non-uniform linear arrays, employing uniform and non-uniform weights, proposed in literature. Conventionally, non-uniform weighting techniques such as binomial, Dolph-Chebhychev, etc. have been applied to suppress side lobes at the cost of increased beamwidth. In this paper, we have shown that applying non-uniform weights to the proposed non-uniform linear array, SLL can be suppressed without compromising beamwidth, resulting in increased directivity. The proposed array has been compared with other linear array geometries and weighting schemes in terms of beamwidth, peak side lobe level (PSLL) and directivity.


In order to predict hot deformation behavior of superalloy nimonic 80A, a back-propagational artificial neural network (BP-ANN) and strain-dependent Arrhenius-type model were established based on the experimental data from isothermal compression tests on a Gleeble-3500 thermo-mechanical simulator at temperatures ranging of 1050–1250 °C, strain rates ranging of 0.01–10.0 s−1. A comparison on a BP-ANN model and modified Arrhenius-type constitutive equation has been implemented in terms of statistical parameters, involving mean value of relative (μ), standard deviation (w), correlation coefficient (R) and average absolute relative error (AARE). The μ -value and w -value of the improved Arrhenius-type model are 3.0012% and 2.0533%, respectively, while their values of the BP-ANN model are 0.0714% and 0.2564%, respectively. Meanwhile, the R-value and ARRE-value for the improved Arrhenius-type model are 0.9899 and 3.06%, while their values for the BP-ANN model are 0.9998 and 1.20%. The results indicate that the BP-ANN model can accurately track the experimental data and show a good generalization capability to predict complex flow behavior. Then, a 3D continuous interaction space for temperature, strain rate, strain and stress was constructed based on the expanded data predicted by a well-trained BP-ANN model. The developed 3D continuous space for hot working parameters articulates the intrinsic relationships of superalloy nimonic 80A.


This paper investigates the interlaminar fracture toughness properties and the self-repair capability of carbon fibre-reinforced epoxy composite laminates incorporating intraply mendable thermoplastic filaments. A carbon fibre fabric was interlaced with mendable filaments of polyethylene-co-methacrylic acid (EMAA) via co-braiding. The EMAA-interlaced carbon fabric layers were stacked to create a pre-form which was subsequently thermo-formed and epoxy resin-infused to manufacture carbon-epoxy laminates. The effects of intraply-located EMAA filaments on the mode I interlaminar fracture toughness and self-healing efficiency of the carbon-epoxy composite were investigated. Results from this study showed that the presence of EMAA improved the interlaminar fracture toughness (both the crack initiation and steady-state crack growth resistance) of the carbon-epoxy composite and enabled healing of the delamination crack. The delamination crack growth resistance of healed-composites containing EMAA was found to be superior to that of the baseline composite (without EMAA).


Several methods for determination of elastic–plastic parameters by instrumented spherical indentation tests have been presented in the past few years. Each method was established according to a specific constitutive model. Identification of the constitutive models of new materials has become an indispensable step in order to choose an appropriate indentation method to extract the elastic–plastic parameters. In the present work, the half depth energy accumulation rate and Meyer's index were related to the elastic–plastic constitutive models via qualitative and numerical analyses. A method for identification of the elastic–plastic constitutive models by instrumented spherical indentation test was proposed.


Follicular lymphoma (FL) is the most common indolent B-cell lymphoma in western countries. Overall, 70% of patients achieve complete remission after first treatment.[1][1] However, it is characterized by a pattern of relapsing and remitting disease. The outcome of patients with FL has clearly


Abstract Specifications are provided for a device for collecting human parotid saliva. The equipment has been designed to make it easy to construct, to sterilize, and to wear.


The Roadrunner (Geococcyx californianus) is a diurnal ground-dwelling cuckoo, which is a permanent resident in the arid and semiarid regions of southwestern North America. Some features of its physiology are known (Calder and Bentley 1967; Calder and Schmidt-Nielsen 1967; Calder and Schmidt-Nielsen 1968; Calder 1968). However, the presence of a salt-secreting nasal gland (Ohmart 1972) and studies on the efficiency in body water turnover in birds under simulated desert conditions (Ohmart et al. 1970) indicated that detailed field information was needed to inte-


Artificial neural networks have been proven to be effective learning algorithms since their introduction. These methods have been widely used in many domains, including scientific, medical, and commercial applications with great success. However, selecting the optimal combination of preprocessing methods and hyperparameters for a given data set is still a challenge. Recently a method for supervised learning model selection has been proposed: Particle Swarm Model Selection (PSMS). PSMS is a reliable method for the selection of optimal learning algorithms together with preprocessing methods, as well as for hyperparameter optimization. In this paper we applied PSMS for the selection of the (pseudo) optimal combination of preprocessing methods and hyperparameters for a fixed neural network on benchmark data sets from a challenging competition: the (IJCNN 2007) agnostic vs prior knowledge challenge. A forum for the evaluation of methods for model selection and data representation discovery. In this paper we further show that the use of PSMS is useful for model selection when we have no knowledge about the domain we are dealing with. With PSMS we obtained competitive models that are ranked high in the official results of the challenge.


It is an important component of harmonious development and the exploitation strategy of the western China to collaborate economy and harmonize development between east and west parts of Yangtze River Basin. Firstly , the paper analyzed the potential and prominent superiority of the Yangtze River Basin in policy, natural resources, mutual industry recruitment and area location etc. Furthermore, it addressed the acollaboration and existing problems, between the west and east of the River Basin, such as handicap in the passage, the bad economic macrocosm, the incompact inter relations and shorts of the person with management ability etc. The paper proposed to reinforce basic establishment, to unitedly explore resources, strengthen the protection of environment, to collaboratively explore the regional market etc. At the same time, it brought forward some problems which should be paid attention to in the process of the collaboration, such as the construction of the mechanism of the economics harmony, the confirmation of the main body of economic collaboration of the River Basin and establishment of the policy to guide its further development.


Essential Cases: Equity & Trusts provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in Barclays Bank Plc v O'Brien [1994] 1 AC 180, House of Lords. The document also includes supporting commentary from author Derek Whayman.


In this research work, the design of pipe in pipe, shelland-tube and combined heat exchanger (previously mentioned types were combined to consider as one unit) has been made. These three heat exchangers have been utilized for two kinds of flows i.e., parallel as well counter flow types individually. The design of combined heat exchanger takes been proposed with the idea of increasing the heat transfer area and to understand the behavior of various parameters involved by comparing with the individual heat exchangers. 75:25 aqueous Ethylene Glycols, have been used as the working fluid in all three heat exchangers of counter as well parallel flow conditions. Total quantity of working fluid is 12 liters, in which 6liters of fluid is used as cold fluid and the other half is used as hot fluid. As a result, overall heat transfer coefficient (U) has been increased with increase of mass flow rate. Highest overall heat transfer coefficient value observed as 1943w/m2 -k at highest mass flow rate (within the considerations of this work) of 0.145 kg/s. The highest decrement in LMTD recorded for 0.0425 to 0.145 increase of mass flow rate is 49.32% in shell-and-tube heat exchanger of parallel flow arrangement. The highest effectiveness is observed for pipe in pipe counter flow heat exchanger case, which is 0.39 at a mass flow rate of 0.145kg/s.


This article presents the results of a study of the dynamics of fiber formation in an interspecific hybrids of G.hirsutum L.x G.barbadense L. The experiments were carried out on hybrids of cotton G.hirsutum L.x G.barbadense L during their period of growing between 3070 days.


In this paper we introduce the Alternating Direction Implicit (ADI) method for non-steady state conditions simulating of convection-diffusion transport of matter in electrochemical cell with a channel microband electrode. Our digital approaches basis at i) non-uniform grid by x, y and t coordinates and ii) an automatic selection uniform (ASU) grid for efficient and stable solution. Calculated results for each from two approaches we compared between both ones and with the experimental data.


We revisit a homogeneously broadened ring laser that is driven by an external coherent signal. We identify new basins of attraction and calculate the dimensionality of the chaotic regions by using both the Kol'mogorov and Lyapunov formalisms. As a function of the driving-field amplitude, we see the dimensionality of the chaotic regions globally decrease in fractal dimension and locally decrease linearly immediately before the emergence of a periodic attractor. New evidence shows that this complex system is governed by only a few attractors; these attractors can coexist, govern independently, or compete for dominance in the chaotic regions. Arguments reveal that, at least for this system, the ideas of distinct chaotic attractors and windows of periodicity within chaos are misnomers and are misleading.


The catalytic ozonation efficiencies of p-chlorobenzoic acid(p-CBA)by petroleum coke,activated carbon(AC)prepared by petroleum coke and Ni/AC catalyst were investigated.The results show that adding petroleum coke cannot significantly improve the degradation efficiency of p-CBA by ozone,but can promote mineralization of p-CBA by ozone.The removal of TOC by AC prepared by petroleum coke after water pretreatment is better than that by AC prepared by petroleum coke after acid pretreatment.When Ni/AC catalyst is applied for catalytic ozonation of p-CBA,and the initial p-CBA concentration is 10 mg/L,the removal rates of p-CBA and TOC are 100% and 60% respectively after 60 min.


In this paper, swarm optimization hybridized with differential evolution (PSO-DE) technique is proposed to solve static state estimation (SE) problem as a minimization problem. The proposed hybrid method is tested on IEEE 5-bus, 14-bus, 30-bus, 57-bus and 118-bus standard test systems along with 11-bus and 13-bus ill-conditioned test systems under different simulated conditions and the results are compared with the same, obtained using standard weighted least square state estimation (WLS-SE) technique and general particle swarm optimization (GPSO) based technique. The performance of the proposed optimization technique for SE, in terms of minimum value of the objective function and standard deviations of minimum values obtained in 100 runs, is found better as compared to the GPSO based technique. The statistical error analysis also shows the superiority of the proposed PSO-DE based technique over the other two techniques.


This paper aims to trace the process of teaching and learning in writing with students of English as a foreign language (EFL). This experiment is translated through an exchange of dialogical journals via e-mail; such journals may be used not only as a communication channel, but also as an additional environment for the development of language and for teaching. The journals, used both as research and learning tools, proved to be effective in raising interest, motivation, production and learning in terms of the written language, by breaking up with traditional practices of teaching.


Triclosan (TCS) and triclocarban are a group of chemicals that pose microbicidal properties and can perform bacteriostatic and fungistatic activities. Because of these properties, the applications of TCS are not only limited to the healthcare industry but are also being widely used in cosmetic and personal hygiene products. Lately, TCS has been used in a wide range of daily-use products (antibacterial toothpaste, hand sanitisers, soaps, hand washes, deodorants and others) to enhance the substance's antimicrobial and 'germ-free' properties.1 This wide use of TCS in day-to-day products has also raised several concerns over the adverse impacts on health. TCS is also known for its stable nature, and it can survive in the residential drains and sewage treatment plants for longer periods.2 This constant interaction of TCS with faecal microbes of wastewater may further have undesired outcomes including antibiotic resistance. The US Food and Drug Administration realised the severity of …


The numerical method is proposed for solving the ventilation problem of mine roadways and gob areas. The results of air distribution calculations for some block ventilation schemes are presented.


BACKGROUND
The molecular basis of genetic predisposition to pulmonary tuberculosis (PTB) in adults remains largely elusive. A chronic granulomatous inflammatory reaction is one of the main characteristics of the immune response to TB; however, a similar reaction is observed in other diseases, such as Crohn's disease.

OBJECTIVE
To assess the association of genetic polymorphisms previously associated with Crohn's disease and PTB in a Colombian population of PTB patients and controls.

DESIGN
A case-control study was performed among 500 newly diagnosed PTB patients and 320 healthy control subjects. Thirty-one single nucleotide polymorphisms (SNPs) identified in a previous meta-analysis of genome-wide association studies of Crohn's disease were used for genotyping using MassARRAY technology.

RESULTS
In this study, we identified an association with borderline significance (P = 0.0009433 and P = 0.029 after multiple testing by Bonferroni's correction) of SNP rs10995271 with PTB. SNP rs10995271 is in linkage disequilibrium with SNPs belonging to the zinc finger protein (ZNF365) gene.

CONCLUSIONS
Our results suggest that human PTB shares a genetic basis with Crohn's disease, and that SNPs in the ZNF365 gene would have a role in the occurrence of chronic granulomatous inflammatory reaction in TB as well as Crohn's disease.


 Abstract — This paper demonstrates a review of electromagnetic field analysis of metamaterials. First it is verified that a double negative metamaterial (both permittivity and permeability negative) forms left handed triplet and consequently, in such a material, wave propagation vector is anti-parallel with Poynting vector. Furthermore, a purely left handed transmission line model has been verified and it is analytically shown that, in such a media, refractive index is negative. It is also investigated that an effective negative permittivity medium or single negative metamaterial can be analyzed by employing a simple equivalent transmission line model which enables us to formulate the wave equation for plasma medium. In the end, some of the applications of double negative and single negative metamaterials are also mentioned.


Abstract : Composition C4, bulk and extruded, was detonated in configurations representative of orthorhombic shipping boxes and a simulated in-plant dryer bed. Blast output parameters were measured and TNT equivalencies computed based on comparison with TNT hemispherical surface bursts. The results indicated that peak side on pressure and scaled positive impulse values were generally greater than 100%. TNT equivalencies varied due to the effect of geometry.


The present invention discloses a hydroformylation process, comprising the steps of: 1) methanesulfonyl chloride and N, N- dimethylformamide or N- methylformanilide formylating agent to form a complex; 2) the formylating agent and an aromatic substrate to form a complex intermediate; a 3) an intermediate complex by hydrolysis with water to form a formylated product of aromatic substrates. The hydroformylation process of the present invention includes a simple process, low cost, high yield, simple operation, and greatly reduce injury to the operator's advantage, suitable for industrial production.


In the current era of computer technology is no longer a taboo. But has become a daily necessity that is used to do many things that are made as a learning tool for users both among students at school or among the public. Basic guitar learning application with the concept of interactive multimedia is a trend among developers of applications and the world of formal education in the country. Application that contains pictures and basic key guitar sound and video writer who uses the Flash 8 software, the latest series of the Macromedia Flash output that can incorporate various multimedia elements such as text, graphics, animation and sound. With Action Script, an interactive movie can be made into interesting.


In the age of constantly evolving technology, network communication has become more critical than ever. Along with this, the need for secure channels for edge communication is undeniable. Two traits of the quality of desirable network protocols are security and reliability. However, these protocols have associated risks. In this work, we provide an in-depth analysis of dominant network protocols on which the new communication protocols (e.g., CoAP, XMPP, AMQP, etc.) of the Internet of Things (IoT) ecosystem heavily relies on.


Introduction:Acute myeloid leukemia (AML) is a heterogeneous clonal stem cell malignancy characterized by proliferation of immature hematopoietic cells. Adipokines in particular leptin and adiponectin are highly active molecules that attracted considerable interest due to their potential role in the development of cancer as a risk factor.We aimed to measure the body mass index, serum levels of leptin and adiponectin in AML patients, correlating these levels with standard prognostic markers of the disease. Materials and Methods:A total of 60 newly diagnosed AML Egyptian patients attended to NCI, Cairo University and twenty healthy controls age and sex matched were enrolled. Serum Leptin and Adiponectin were assayed in both patients and controls by enzyme linked immune assays. Results:significant lower serum levels of leptin and adiponectin were detected compared to controls (p< 0.02, <0.001) respectively. No significant correlation was detected between serum adipokines and other laboratory parameters except a negative significant correlation was detected between serum adiponectin and bone marrow blast. Regarding cytogenetic analysis, no significant correlation between cytogenetic and serum leptin and adiponectin levels (p=0.98, 0.38) respectively. The current study addressed the reduction of adiopcytokines levels in AML together with negative correlation between bone marrow blasts and adiponectin levels suggesting the implication of adipocytokines in pathogenesis of AML, however these findings necessitate additional studies on large scale of cases International Journal of Comprehensive Leading Research In Science ( ISSN: 2455-4693 ) , Vol. 1 Issue 2, pp: (62-77), January 2015, Available at: www.ijclris.com 63 www.ijclris.com


To analyze the adaptive connection admission and flow control (ACAFC) strategy, we need a queueing model with complex arrival and service characteristics using the underlying arrival phase and service type processes. To solve the queue, we have to study the matrix analytic approach. We use the blocking method (BM) to get the exact solution for the finite queue, however, when the system size becomes larger, the method is slow; thus, we use an infinite queue to approximate the finite queue with the normalizing method (NM). It is shown that the BM is slow compared with the NM based on the adaptive Newton-Kantorovich (ANK) algorithm for an infinite queue, when the system dimension is larger than 35. We investigate how accurate the NM is when it is applied to the matrix analytic model, and the results show that the NM works pretty well as long as the load intensity is less than 0.9; and for most of the common situations we met, both methods consistently show that the level of cell loss probability, for an ATM network using adaptive CAFC, is inversely and linearly proportion to the buffer size. A new call is accepted only when the cell loss probability is less than a certain level, or the quality of service (QoS) is satisfied. The linear relation allows us to obtain the performance of a large system based on the calculation of a small system which is fast. This may provide us with a fast ACAFC algorithm for ATM networks.


Purpose: Present a method to calculate IMRT plan weight or dose to a point from IMRT plan MU settings, capable of being performed manually or with a simple spreadsheet. Applicable to step and shoot IMRT plan MU check calculations. Show how this method corelates to QA measurement results. Method and Materials: Employ beam data tables commonly available for calculating MU settings for 2D and 3D plans. Use simplifying assumptions on the beam equivalent size and the number of MU to apply to producing dose directly and from scatter or leakage to the point of interest based on geometric considerations. The procedure and assumptions will be described. The MU check results will be compared to the beam IMRT plan QA measurement pass/fail results. A 2D diode array was employed for IMRT plan QA measurements. Results: 42 IMRT step and shoot plans have been evaluated. Plan point dose calculated with this procedure fell within 2.5% of the plan value for 35 of the 42 cases. None of these plans failed the measured QA criteria of 3%dose / 3.0 mm DTA gamma evaluation or the 5% point dose measurement criteria. 7 plans had MU point dose results differing by > 2.5%. 2 of these 7 plans failed either the dose measurement QA test or the gamma test. Conclusion: This calculation method shows promise as a plan evaluation tool.


Quantum mechanical calculations on the three dimensional non-reactive, vibrational relaxation process H + HF (v, j →v', j') are presented. The centrifugal sudden approximation is employed together with a recently developed localized form of rotational basis function which is shown to accelerate the convergence of the close-coupling calculations for this collinearly dominated system. A calculated rate constant for the v=1 »0 vibrational transition in non-reactive H + HF is compared with those obtained in experimental measurements.


Passive smoking can cause death from lung cancer and coronary heart disease, but there is little evidence for associations with other causes of death in never smokers. A recent study showed increased all cause mortality with exposure to secondhand smoke at home but did not examine associations with specific causes of death and dose-response relations.1 We have published estimates of the mortality attributable to active smoking in Hong Kong2 and now present the related findings on passive smoking at home.

Details of the sample selection and data collection have been reported.2 Each person who reported a death in 1998 at four death registries was given a questionnaire which asked about the lifestyle 10 years earlier of the decedent and of a living person about the same age who was well known to the informant. Passive smoking was identified in the interview with the question, "Ten years ago, in about 1988, excluding the decedent/control, how many persons who lived with the decedent/control smoked?" Decedents or …


The aim of this study is to investigate the impact of Industry 4.0 adoption and operational performance improvement due to apply Total Quality Management (TQM) and Total Productive Maintenance (TPM). The analyzed sample was collected from 147 Brazilian manufacturers which have been practiced TQM and TPM for at least 10 years and during the past few years have started to adopt Industry 4.0 technologies. Multivariate data analysis was applied into the collected data in order to examine such relationships. Our statistical tests indicate that both TQM and TPM practices act as mediators for the relationship between Industry 4.0 and operational performance improvement. Hence, we mention that the companies which decide to join Industry 4.0 must have properly addressed these practices to entirely benefit from the advances in information and communication systems. This study contributes to threefold. First, it provides evidence to underpin theoretical indications previously argued but lack empirical validation. Second, the identification of relationship in an emerging economy context allows to understand the specific benefits or challenges that Industry 4.0 adoption. Third, comprehending how these approaches interact to help managers to avoid difficulties and set the suitable expectations along their implementation.