Purpose To report staphylococcal endophthalmitis following cataract extraction in a patient with Darier's disease. Methods A 67-year-old man presented with decreased visual acuity OD and hypopyon 3 days status post-cataract extraction with intraocular lens placement. The patient was hospitalized and placed on topical and intravenous antibiotics. A diagnostic vitreous tap, pars plana vitrectomy, and intravitreal antibiotic installation were performed. Results Vitreal tap cultures indicated Staphylococcus epidermidis. His clinical status improved after vitrectomy and antibiotic therapy. The same bacteria was cultured from the patient's eyelids. Conclusions The source of the S. epidermidis was the skin lesions on the patient's face and eyelids. Darier's disease is an exfoliative hyperkeratotic skin disease that affects all areas on the body except the buttocks. Although clean, sterile surgical techniques were followed, the risk of endophthalmitis following intraocular surgery in a patient with Darier's disease may be increased due to his or her dermatologic condition.


This chapter is largely preliminary in nature; it consists of a brief review of some of the terminology and the elementary theorems of general topology, an examination of the new concept "linear topological space" in terms of more familiar notions, and a comparison of this new concept with the mathematical objects of which it is an abstraction. After an introductory section on topology, we consider linear topological spaces, subspaces, quotient spaces, product spaces, and linear functions. With the exception of a few simple propositions relating to circled sets, these theorems are specializations of familiar results on topological groups (in other words, little use is made of scalar multiplication).


Student mobility within the European Union is as important for the individual student as it is for the European economy and the attempt to strengthen a sense of common European identity. However, students wishing to study abroad risk encountering serious financial obstacles. The present article suggests that it may be possible to rely on free movement law in order to claim portable financial support from the home Member State to a greater extent than can be inferred from the case law specifically addressing the subject. It does so by pointing to inconsistencies with the case law on Union citizenship and by way of a comparison with cross-border provision of public healthcare services, arguing that a denial of the right to portable support can be perceived as an unjustified obstacle to free movement. Finally, the
need to reconcile an increase in support for student mobility with the Member States' interest in limiting financial responsibility is discussed. While it may be possible to achieve some improvements through legislation, it is argued that developments of a judicial nature are more likely, albeit not entirely unproblematic.


NOTE: This statement is intended for those lifesavers, acting in a professional or volunteer capacity, who are trained in the techniques of water rescue and resuscitation and who assume a duty to safeguard members of the public at aquatic sites. They may be called lifeguards, lifesavers or both. This statement is not directed at members of the public trained in water safety and rescue techniques, but without a duty to respond, who may also be known, in some areas of the world, as lifesavers.


The magnetocrystalline anisotropy theory developed earlier by us and based on a novel energy level model for Fe2+ in YIG:Si(Ge) is used here to study the mechanism of spin reorientation in YIG:Si. Single-ion anisotropy with a uniform distribution of Fe2+ ions indicate a broad spin reorientation which turns out to be due to the higher-order cubic terms K3 and K4. It is found that the completion temperature (T2) of the spin reorientation is strongly influenced by K4 thus indicating an inadequacy of the approach based on K1, K2 and K3 only. From the single Fe2+ ion anisotropy results we propose a two-center model which implies a new mechanism of the spin reorientation in YIG: Si. The bulk onset (T1′) and completion (T2′) temperatures are linked to the relative number (a) of the near Fe2+ sites. Spin orientation diagrams in the plane a - T are established for the total Fe2+-Fe3+ system for a wide range of the parameters involved. The two-center model accounts well for the bulk experimental temperatures T1′ and T2′ in YIG: Si and for the absence of spin reorientation in samples having Si-content less than 0.18. The total magnetization M is predicted not to rotate smoothly between the [100] and [111] direction. There exists an upper critical angle beyond which M switches sharply to [111] as the temperature approaches T2′. Comparison with the previous model which requires a nonuniform distribution of Fe2+ ions is also discussed.


During the time of Liang in the Nan Dynasty,the brothers,Xiaotong and Xiaogang,were in charge of editing "Wenxuan"and"Yutanxingyong"respectively.This paper makes a comparative study of the purpose of compiling these two books,different structure, the authors and their works,their respective understanding of literature and their influence on the following generations so as to reveal the values,gains and losses.


This descriptive-quantitative study is aimed at finding out the types of impoliteness super-strategies used by Sylvie toward her employee, Emily, in Emily in Paris season one, as well as the most and least frequently used types. The main theory used is Culpeper's (1996, 2005) impoliteness strategy. The findings reveal that Sylvie has implemented all five types of impoliteness super-strategies. The most common is negative impoliteness which most likely occurs because Sylvie always opposes Emily on purposes despite knowing how much Emily wants to be professionally acknowledged at Savoir. The least frequently used is withhold politeness, which might happen because although Sylvie is a generally nice person, she uses clearer impolite strategies to Emily on purpose. The writers conclude that Sylvie purposefully uses impoliteness strategies and adds impolite gestures, to bring Emily down and to emphasize her power to get rid of Emily from Savoir. Keywords: impoliteness, impoliteness strategy, status, utterance


The treatment given a patient with meningitis (Streptococcus haemolyticus) following mastoiditis which complicated scarlet fever is of interest, as it was followed by the unusual result of complete recovery. Surgical drainage of the mastoids was done. The value of repeated blood transfusions 1 to combat the strong hemolyzing influence of this type of infection was recognized, and that agent was used. Frequent spinal taps were done for the reduction of intracranial pressure. In addition to the aforementioned treatment, the following therapy was used: convalescent scarlet fever serum 2 both intravenously and intraspinally together with a derivative of sulfanilamide (prontosil) 3 intramuscularly and sulfanilamide by mouth. 4 REPORT OF CASE J. W., a boy 6 years old, was admitted to the scarlet fever ward of the Willard Parker Hospital on Oct. 28, 1936, the fifth day of his illness. Five days before coryza had developed, with malaise; on the following day a slight rash on


This article discusses the situation of high-speed railway lines in Germany, and briefly refers to the situation in the rest of Europe and in Japan. A map shows the infrastructure plan of the European high- speed rail network up to 2010. Germany differentiates between completely new routes (NBS) and existing routes upgraded to a higher standard (ABS). The underlying reason for choosing to construct an NBS is lack of capacity on lucrative rail routes. An NBS not only raises capacity within the rail network, but also improves quality by allowing the installation of the latest technology and generous alignment standards. The maximum NBS speed is set between 250kph and 300kph. ABS have maximum design speeds of 200kph, but sometimes have sections allowing up to 250kph. Sometimes, an ABS serves as an extension of an NBS route. German Railways (DB) has both NBS routes catering for mixed traffic, and those only carrying fast, lightweight trains. Given equal conditions, a purely high-speed route involves a lower proportion of large structures than one designed for mixed traffic. However, some high-speed routes have a very high proportion of large structures, especially when passing through unfavourable topography or areas with high population density.


Proficiency standards for thirty-nine critical math skills were developed based on the performance of 49 adults whose chosen careers required mathematical skills. These standards will help regular education teachers write and meet basic skill objectives. Also, special education teachers can use these standards in individualized education plans and to improve mainstreaming efforts.


The author discusses clinical applications of electrical impedance tomography using the Sheffield applied potential tomography system. The examples given are: diagnosis of ventilation deflects; monitoring intrathoracic fluid volumes; continuous monitoring of ventilation.


Multi-parameter estimation is investigated for target discrimination and localization in multiple-input multiple-output (MIMO) radar system. With an M-element uniform linear array in the transmitter and a square array consisting of N2 pair of crossed-dipoles in the receiver, a novel method is proposed for joint estimation of direction-of-departures (DODs), two-dimensional direction-of-arrivals (2D-DOAs) and polarizations of multiple targets for bistatic MIMO radars. Its signal model is described, and the algorithm is given by exploiting rotational invariance property of ESPRIT and polarization sensitive array processing technology in transmit and receive arrays. To discriminate and localize targets in a 3-D plane, more information than those of traditional bistatic MIMO radar algorithms is provided using the proposed method. Also, by making use of polarization diversity, its resolution capability is greatly improved when two targets are closely spaced.


The International Self-Report Delinquency (ISRD) has become increasingly used among researchers to study the prevalence and incidence of crime and juvenile c...


The gills, functioning as simple membranes in exchange with the external medium, account for 90 % of total 4Ta uptake and 70 % of total output. Exchange also occurred across abdominal cuticle and via the anus (net outwards exchange 13 % and 7 %, respectively, of total). The long midgut appeared to be a site of calcium excretion. Antenna1 gland output was only 0.5% of the total. Blood 46Ca uptake gave an exponential curve, resolved by graphical analysis into three components: (1) a "fast" component due to completely reversible exchange across the gills; (2) a "medium" component due to loss via the abdomen; and (3) a "slow" component due to deposition in the cuticle. Calcium was lost rapidly in calcium-low artificial seawater, and most of the loss was made good within 24 hr. Calcium above normal levels did not result in a significant increase in body calcium. 45Ca was freely exchangeable between soft tissues but complete exchange did not occur with the external medium, largely due to "bound" calcium in the cuticle. Calcium in the exocuticle was revealed only by histochemical tests, but visible calcium deposits occurred at the exocuticle-endocuticle interface. The latter begin at scattered calcification centres, grow concentrically, and may become confluent; deposition continuing through the intermoult period. This type of calcification appears to occur in a number of Malacostraca. Calcium ot the exocuticle seems to be "bound", but that of the interface is labile and apparently serves as a calcium (or alkaline) reserve, though this calcium does not appear to be resorbed prior to ecdysis.


The leakage detection is using temperature characteristics of the leak point and infrared radiation signals to locate the leak point.The key to achieve the best detection result is to increase the temperature difference between the leak point and around.Diameter of the inflatable orifice,pressure and temperature of the air will impact the temperature difference.Through theoretical analysis,s imulation and experimental analysis,to get the temperature change during charge and discharge process in different testing conditions,and given the new strategy using infrared images when temperature difference ΔT is near the extremum to diagnose the leakage.And the effectiveness is verified through the actual image processing algorithms.


Here, the employment of multilayer perceptrons, a type of artificial neural network, is proposed as part of a computational funneling procedure for high‐throughput organic materials design. Through the use of state of the art algorithms and a large amount of data extracted from the Harvard Clean Energy Project, it is demonstrated that these methods allow a great reduction in the fraction of the screening library that is actually calculated. Neural networks can reproduce the results of quantum‐chemical calculations with a large level of accuracy. The proposed approach allows to carry out large‐scale molecular screening projects with less computational time. This, in turn, allows for the exploration of increasingly large and diverse libraries.


Purpose Certain radiation responsive skin diseases may develop symptoms on the upper or the lower half of the body. The concept of a novel Hemi-Body Electron Irradiation (HBIe - ) technique, described in this work, provides a low cost, LINAC based, intermediate treatment option in between extremely localized and Total Skin irradiation techniques. The HBIe - technique, developed in our department, incorporates a custom crafted treatment chamber equipped with adjustable Pb shielding and a single electron beam in extended Source-Skin Distance (SSD) setup. The patient is conceptually positioned in custom 'Stanford' technique positions. The geometrical setup provides both optimal dose homogeneity and dose deposition up to a depth of 2 cm. To confirm this, the following characteristics were measured and evaluated: a) percentage depth dose (PDD) on the treatment plane produced by a single electron beam at perpendicular incidence for six fields at 'Stanford' angles, b) 2D profile of the entrance dose on the treatment plane produced by a single field and c) the total surface dose on an anthropomorphic phantom delivered by all 6 fields.


Abstract In the previous paper3), we reported a method of synthesizing nitriles from benzyl and alkyl amines by using nickel peroxide as an oxidant. In these reactions, the reaction was initiated by the hydrogen radical abstraction from the methylene and amino groups by nickel peroxide and produced the aldimine intermediate, which was further oxidized to a nitrile. Several papers have been reported describing one-step syntheses of nitriles from the corresponding aldehydes and ammonia in the liquid phase by the oxidation with several kinds of oxidants.


In this paper, the fundamental characteristics on humanistic quality are described in detail. The present situation on humanistic quality for science engineering university students is discussed by a mass of data. Because "instrumentalism" in high education make the students became a common consciousness, which instrumentality is equal to benefit, it is the cause which humanistic quality of science engineering university students is weak.


SiC nanoparticles reinforced magnesium matrix composite was fabricated by ultrasonic vibration assisted squeeze casting. Since ultrasonic device could meet the use requirements according to theoretic calculation, uniform dispersion of SiC nanoparticles was expected to achieve. The grains of the composite were refined compared with the AZ91 alloy, which was related to the increase of nucleation sites during solidification and Zenner pinning effect caused by SiC nanoparticles. With increasing the ultrasonic power, grain size of the composite changed no obviously while the morphology of β-Mg_17Al_12 phase was significantly affected. The ultimate tensile strength, yield strength, and elongation to fracture of the composites fabricated under different ultrasonic powers were simultaneously improved compared with the AZ91 alloy. The increase of yield strength could be attributed to Hall–Petch strengthening and Orowan strengthening for the present composites. Theoretical value of the yield strength obtained by the square root method was close to the experimental value.


p-Aminopyridines were oxidatively substituted at the C31-position of methyl pyropheophorbide-a, one of the chlorophyll-a derivatives. The electron-donating p-(dimethyl)amino groups induced silver m...


1 Professor Emeritus, Department of Food Science and Nutrition, University of Minnesota, 1334 Eckles Ave., St. Paul, MN 55108, USA 2 Full Professor, Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, United Kingdom Copyright: © 2021 Paul B. Addis, Martin Grootveld. This is an Open Access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. https://www.thegms.co


Optimal methods for processing input information signals often involve operations, implementation of which is extremely difficult and significantly increases the requirements for automated information processing systems. However, the use of various approaches to solving this problem has led to the appearance of synthesized methods for processing a sequence of signals that allow solving the detection problem with the required quality without significant hardware complications. The article considers a method for weightless processing packets of input quantized signals, which allows us to evaluate the potential (limit) quality of information processing and quantify the amount of loss of this quality when excluding certain operations. The considered method is given with a reasonable structure of implemented devices in practice. A special feature of weightless signal processing is analysis of increasing unit density in a fixed interval of close positions, which gives information about the possible presence of an information signal. To identify this factor, two logical criteria are used, such as "m out of m" and "n out of m", which will be described in this article.


It discloses a method of improving the vibration damping of a substrate, such as automotive underbody. The method includes applying a plastisol containing a polymer component and polymeric plasticizers. Fusion plastisol has an attenuation behavior improved as measured by a dynamic mechanical thermal analysis. Also disclosed is a novel plastisol. .BACKGROUND


Popular is the inherent requirement of Marxist philosophy,but for a period of time since,"philosophical theory is useless"has influence by more and more people in China,and gradually formed a kind of ordinary people do not understand philosophy,young students don't love philosophy and philosophy only concerned philosophy strange phenomenon.Adctually,from Maozhdong put Marxist philosophy with Chinese traditional culture,especially the Chinese traditional philosophy and the Chinese way of thinking of organic combination of process can see,only to find the right path and method,Marxist philosophy must be popularized in China.


The enormous number of images of works of art available on the Internet promises great potential for research in art history and related image-using disciplines. Yet without adequate indexing, this resource is very difficult to explore. It is certainly necessary to identify each image with the basic unique information relating to it, but more is needed. Since it is largely the concepts related to works of art that interest art historians, it is these concepts that need to be reflected in indexing terminology. As these concepts have changed over time, a sizeable verbal infrastructure is needed to support the indexing of large image databases to achieve maximum use by art historians.


The numerous advantages of foamed polystyrene (FPS) food ware over other food service wares increase its demand in food packaging services. The large demand for these products resulted to an accumulation of about 4-5 tons per day of post-consumer waste FPS in Metro Manila. The product made from recycling waste FPS in used oil is a probable wood substitute. This thesis aims to evaluate the mechanical properties of the recycled FPS as a wood substitute and to determine the waste FPS to oil ratio that would produce the strongest recycled product. Varying proportions of waste FPS were melted at temperatures of 160, 170, 180, 190, or 200 oC. The resulting products were evaluated of their compressive strength, modulus of rupture, and hardness. The ratio of 3 parts waste FPS to 1 part used oil yields the strongest product. The compressive strength and the modulus of rupture are increasing with temperature. For both of these tests, the 3:1 ratio tolerates the greater load. The hardness of the materials have hardness ranging from 4-5 or equivalent hardness of fluorite or apatite.


Island floras are diverse with exceptionally high rates of endemicity, and they are also severely threatened. Invasive plants are widespread on islands, but whether islands are particularly susceptible to invasion or island species are more vulnerable to displacement, or both, remains unclear. As part of the "island plant syndrome," it has been predicted that island plants have convergently evolved conservative resource use, slow growth rates, and weak competitive abilities in response to moderate climates and the presumed absence of competition in communities with relatively low species richness. Yet, functional trait approaches have provided mixed evidence to support this prediction, and direct tests of competition as neighbour effects on plant performance are lacking. Considering the extensive environmental heterogeneity that exists within islands and among islands, it seems more likely that diverse functional strategies, spanning conservative to acquisitive, have evolved in island plants. Furthermore, assessing island plant syndrome predictions through comparisons with invasive species, which are nonrandom subsets of continental plants, is a flawed approach. Future studies that compare functional strategies of native island versus native continental plants and direct tests for competition between native and invasive island plants within the local scale at which competition occurs, and that consider non‐additivities with other simultaneous global threats, are urgently needed to conserve these biodiversity hotspots.


Excellence in teaching has always been a demanding and absorbing concern in institutions of higher learning. Earlier studies, which are numerous, have often dealt with the measurement of teacher qualities but have largely failed to explain the phenomenon of excellence in practice. This study focused on the outstanding professional teachers' candid revelations of their subjective experiences of becoming and being excellent in their craft. Findings of the study indicated that love is the touchstone of excellence in teaching: that is, loving the students, loving knowledge and loving the teaching process.


The thresholding method based 2-D maximum entropy and the one based on 2-D minimum cross entropy are used widely in image segmentation today,but in some applications,they fail to segment images because of too high or too low thresholds.Therefore,we proposed an image thresholding method based on the combination of 2-D maximum entropy and 2-D minimum cross entropy.Firstly,the formula of the 2-D minimum cross entropy was transformed,then 2-D maximum entropy and 2-D minimum cross entropy were combined together using multi-objective programming theory so that the optimal threshold value could satisfy the threshold requirement of the both.A new recursive algorithm was inferred using the features of the 2-D histogram in order to search the best threshold vector and to reduce the computing complexity.Experimental results show that: 1) the proposed method is effective and can compensate the shortcomings of the two methods in some applications;and 2) the computation time is less,which is about 0.3 second.


The movement of water through the soil profile and the consequent displacement and transformation of chemicals dissolved in the water is a key concern in preventing water quality degradation, with its eventual impact on living systems, both human and otherwise. Predictions of the effect of a particular water and chemical management system at the soil surface will lead to more enlightened control of chemicals introduced into the environment as pesticides, fertilizers, or waste products. The use of geographic information systems (GIS) in concert with simulation modeling of soil leaching processes is becoming more widespread as a procedure applied to environmental chemical fate issues. The use of GIS has brought to the forefront the spatial scale of such databases as soil survey, elevation, climate and land use, and their use in the modeling process. An accompanying concern is the spatial scale at which any simulation model is assumed to be accurate, and the spatial scale at which both model input and field-verification data should be generated. Such modeling presently consists of a number of approaches, some useful at several spatial scales, and others more limited by the assumptions inherent in their development. This paper discusses these issues, and presents two case studies as examples.


This report discusses the following topics: Polymeric systems; Lead halide-containing fast ion conducting glasses; Mixed ionic electronic conduction; Plastic crystals; and Mobile ions as a basis for high impact ceramics.


Restricted by the individual aesthelic standard mechanism, Stendhal lays emphasis on analysing the inner world of the characters,whose creations display internal tendency. However Balgac reveals and castigates the social drawbacks in particular, whose creations display external tendency.Both of them enrich and perfect the creations of critical realism from various aspects.


We investigated the operating characteristics of the hybrid-type superconducting fault current limiter (SFCL) according to the inductance of secondary windings. The hybrid type SFCL consists of a transformer that has a primary winding and a secondary winding with serially connected YBa₂Cu₃O? (YBCO) films. The resistive-type SFCL has difficulty when it comes to raising the capacity of the SFCL due to slight differences of critical current densities between units and structure of the SFCL. The hybrid-type SFCL with closed-loop is able to achieve capacity increase through the electrical isolation and reduction of the inductance of the secondary winding with a superconducting element of the same critical current. On the other hand, the current limiting characteristics were nearly identical in the hybrid-type SFCL with open-loop compared to closed-loop, but quench time was longer than the hybrid-type SFCL with closed-loop. We confirmed that the capacity of the SFCL was increased effectively by the reduced inductance of the secondary winding. In addition, the power burden of the system also could be lowered by reducing the inductance of secondary winding.


American Journal of Botany 99(3): 552–561, 2012; http://www.amjbot.org/ © 2012 Botanical Society of America The tendency of fungal pathogens to switch hosts remains an important fi eld of study as humans facilitate the intentional and unintentional dissemination of biological materials across the globe. Of particular interest are the fungi traditionally classifi ed in Clavicipitaceae (Ascomycota: Hypocreales), whose members play important roles in biological control efforts, and also represent important pathogens of food crops ( Scholte et al., 2005 ; Kanzok and Jacobs-Lorena, 2006 ; Haarmann et al., 2009 ). The use of molecular phylogenetics has greatly advanced our understanding of relationships and the evolution of nutritional modes for these fungi. Previously considered a single large and diverse family, Clavicipitaceae sensu Rogerson (1970) is now recognized as encompassing three families, Clavicipitaceae s.s., Cordycipitaceae, and Ophiocordycipitaceae ( Sung et al., 2007 ). Pathogens of plants are unique to Clavicipitaceae s.s. and are hypothesized to have evolved from animal pathogenic ancestors at least twice. Species infecting other fungi are known from all three families and are represented in Clavicipitaceae by a single asexually reproducing species, Verticillium epiphytum ( Spatafora et al., 2007 ). In spite of advances in our understanding of phylogenetic relationships and evolution of nutritional modes, many species of clavicipitoid fungi remain inadequately sampled and their ecology unknown. Phylogenetic analyses and ancestral character state reconstructions support an origin of arthropod pathogens near the Jurassic – Cretaceous boundary, essentially concurrent with the rise of angiosperms and the modern orders of phytophagous insects ( Sung et al., 2008 ). The subsequent acquisition of plant and fungal hosts are supported as shifts from arthropod hosts ( Spatafora et al., 2007 ). Theoretical explanations of how such divergent host ranges evolved among closely related species have been limited to specifi c cases and have involved two possible hypotheses. The host habitat hypothesis posits that new hosts are acquired due to their proximity in the environment, whereas under the host relatedness hypothesis, pathogens are more likely to jump to new species closely related to the original host. The host habitat hypothesis was found to explain host jumping between cicada nymphs and false truffl es owing to their co-occurrence near plant roots ( Nikoh and Fukatsu, 2000 ; Spatafora et al., 2007 ). Shifts from animal to plant hosts have not been explicitly tested, although pathogens of hemipteran scale insect hosts (families Coccidae, Diaspididae) have been postulated as the ancestral state ( Hywel-Jones and Samuels, 1998 ; Bischoff et al., 2005 ). 1 Manuscript received 17 March 2011; revision accepted 13 December 2011. Funding was provided by an NSF PEET grant (DEB 0529752) to J.W.S. and two NSF EAPSI grants (OISE 0714106 and 0914288) to R.M.K. 9 Author for correspondence (e-mail: email@example.com)


A new method of measuring the Brillouin gain spectrum of optical fiber is proposed and demonstrated. Unlike existing methods, both the pump light and the counter-propagating probe light are generated from a single laser diode whose optical frequency is directly modulated by injection current modulation. The frequency difference between the pump and the probe is scanned continuously through optical frequency chirp occurring when the injection current is modulated with a square wave. The measured Brillouin gain spectrum of telecom single-mode fiber agrees well with that shown in other literature.


A review is given on the analysis of ferrous alloys. 348 references are given to U. S. and foreign journals published from November 1960 through June 1962. (P.C.H.)


Objectives: While outcomes are favorable for Human Papillomavirus (HPV)-positive oropharyngeal squamous cell carcinomas (OPSCCs), early diagnosis may be beneficial to reduce treatment-related morbidity and mortality. Circulating tumor-tissue-modified viral (TTMV) HPV DNA is detectable in approximately 90% of HPV-positive OPSCC patients and may be a useful diagnostic tool in the clinical evaluation of patients at-risk for the disease. Methods: In this prospective exploratory cohort study, patients presenting to an Otolaryngology-Head and Neck Surgery clinic with unexplained signs or symptoms considered high-risk for HPV-positive OPSCC such as neck mass, tonsillar asymmetry or throat pain were recruited between March 2021 and October 2022. Circulating TTMV-HPV DNA testing was performed by a commercial laboratory (Naveris, Natick MA) and results were shared in real time with the subjects and treating clinicians. Clinicians were surveyed regarding the perceived clinical utility of the test. Medical record abstraction was performed to ascertain subsequent diagnoses. Results: Thirty-nine patients were enrolled. Most subjects were women (N=23, 59%), white (N=32, 82%) and never-smokers (N=20, 51%) with median age of 60 years. The most common presenting sign was tonsil asymmetry (N=24, 62%), while 16 (41%) subjects presented with a neck mass. Circulating TTMV-HPV DNA test results were returned within median 7 days (range, 4-21 days). TTMV-HPV DNA was detected in 2/39 subjects (5%), both subsequently diagnosed with HPV-positive OPSCC. Both were white men in their 70s presenting with a neck mass. One woman with undetectable TTMV-HPV DNA was subsequently diagnosed with HPV-positive OPSCC via excisional neck mass biopsy. Other eventual diagnoses relating to presenting signs and symptoms included 3 HPV-negative head and neck squamous cell carcinomas, 2 branchial cleft cysts, and 4 other malignancies. Treating clinician surveys indicated that while the test impacted clinical management only for 8/38 (21%) subjects, it was perceived as helpful in clinical decision-making for 26/38 (68%) subjects, and as useful for similar future patients in 32/37 (86%) subjects. Conclusion: Plasma TTMV-HPV DNA testing is feasible alongside standard clinical work-up for at-risk patients with particular potential for use as a diagnostic aid for HPV-positive OPSCC. Clinicians should, however, be cognizant of its limitations, and should not consider a negative test result to indicate absence of disease. Further studies to evaluate its utility are warranted.
 Citation Format: Sana Batool, Rosh K. V. Sethi, Annette Wang, Kirsten Dabekaussen, Ann Marie Egloff, Catherine Delvecchio Fitz, Ravindra Uppaluri, Jennifer Shin, Eleni M. Rettig. Circulating tumor-tissue modified HPV DNA testing in the clinical workup of patients at risk for HPV-positive oropharynx cancer: The IDEA-HPV Study [abstract]. In: Proceedings of the AACR-AHNS Head and Neck Cancer Conference: Innovating through Basic, Clinical, and Translational Research; 2023 Jul 7-8; Montreal, QC, Canada. Philadelphia (PA): AACR; Clin Cancer Res 2023;29(18_Suppl):Abstract nr PO-001.


Linear controllers perform well for straight-line path-following autonomous vehicles. For curved paths, significant large errors may result. These can be improved using two linguistic fuzzy-logic controllers (FLCs) even in the presence of inaccurate measurement of path curvature. One of the FLCs is used for accounting the path curvature. Using the linear-to-fuzzy algorithm, the synthesis of the linguistic FLCs is readily achieved. Also using the equivalent transformation algorithm, the stability analysis of the linguistic FLCs can be carried out based on a Lyapunov function which is obtained using the linear-matrix-inequality method. Experimental results are presented to illustrate the effectiveness of the proposed FLCs.


Various embodiments for providing and share comments multiple users to share the content item, to provide a comment system. For example, the user, documents, spreadsheets, photos and Web links to a collection of other content items of some media, etc., can be shared with other users that are stored in the online content management systems. In order to enable such functionality, online content management system, in order to be able to attach to the content item and third-party service providers to develop a comment interface, can publish the application programming interface. Therefore, such a comment computing system, each content each content item the user may provide comments to shared content item or user may provide comments for use as memorandum for personal content items in order to display at the same time side by side with the item, it may provide a comment interface.


A global optimization algorithm was presented for optimizing the 4-D trajectory to solve the follow ing problem: maximize the performance index for the space vehicle,and the performance index of optimal trajectory is to maximize the number of the asteroids w hich the spacecraft met and also maximize the final mass. The optimization algorithm is comprised of static parameters and dynamic control law s. The space vehicle flies starting from the Earth at the time January 1st2015 and then flies around the Sun for 10 years. Based on a great deal of numerical flight simulation by using this global dynamic optimization algorithm,the 4-D optimal trajectory w as obtained for the spacecraft fly by 20 asteroids around the Sun w ithin 10 years.


During the last years more and more discussions came up about the contribution of technology-oriented and technology-intensive industries for the economic development and employment. One reason for these contradictory evaluations of technology-intensive industries can be attributed to different conceptual definitions of technology which are briefly discussed. The foundation and liquidation dynamic of West-Germany is examined for the period 1979-1992 on the basis of a data set from the employment statistics of the Federal Institute of Labour and the Institut fur Arbeitsmarkt- und Berufsforschung (lAB). The result is that there are great differences in the foundation and liquidation performance between technology-oriented, not technology-intensive and selected parts of the service sector. The effect of the economic development is analysed in the final part of the paper, showing that technology-oriented industries are more linked to the economic performance than other industries.


Open reduction and internal fixation with plate and screws is the standard treatment for displaced or unstable lateral malleolar fractures. Despite functional satisfactory results obtained using this technique, complications including infection, skin necrosis, and discomfort caused by the plate are reported in 10-20% of cases. Several minimally invasive techniques have emerged as alternatives to avoid these complications. The present study aims to describe a technique and case report for percutaneous treatment of lateral malleolar fractures applying only screw fixation.


In November 1589, news of a provocative act of vandalism reached the ears of the Elizabethan authorities. Robert Goldesborowe, an outspoken recusant who christened his children ''in corners'' and openly affirmed that all Protestant ministers were knaves, had maliciously defaced an English Bible in three distinct places. One of the passages he chose to mutilate apparently concerned the translation of the Scriptures into the vernacular. Goldesborowe subsequently confessed to this crime of sacrilege ''under his owne hand wrytinge.'' The details of this intriguing case are unclear, but at first glance it could be interpreted as an example of a committed Catholic layman implicitly defending the principle that the Bible should remain forever encased in the alien language of Latin. Protestant propagandists might have alighted upon it triumphantly as evidence of the extent to which the popish priesthood had brainwashed the laity into believing that there was no need for them to have direct access to God's Word in their mother tongue. Like the case of Thomas Fugall, the Yorkshire vicar investigated for cutting a copy of the Bible with a knife during the reign of Mary I, and the ritual burning of English translations at the time of the Northern Rising in 1569, they might have seen it as symptomatic of the Church of Rome's innate hatred of Holy Writ itself.


It is foreseen to significantly increase the luminosity of the Large Hadron Collider(LHC) at CERN around 2018 by upgrading the LHC towards the sLHC (Super-LHC). Due to the radiation damage to the silicon detectors used, the physics experiment will require new tracking detectors for sLHC operation. All-silicon central trackers are being studied in ATLAS, CMS and LHCb, with extremely radiation hard silicon sensors on the innermost layers. The radiation hardness of these new sensors must surpass the one of LHC detectors by roughly an order of magnitude. Within the CERN RD50 collaboration, a massive R&D programme is underway to develop silicon sensors with sufficient radiation tolerance. Among the R&D topics are the development of new sensor types like 3D silicon detectors designed for the extreme radiation levels of the sLHC. We will report on the recent results obtained by RD50 from tests of several detector technologies and silicon materials at radiation levels corresponding to SLHC fluences. Based on these results, we will give recommendations for the silicon detectors to be used at the different radii of SLHC tracking systems. European Physical Society Europhysics Conference on High Energy Physics EPS-HEP 2009, Krakow , Poland July 16-22, 2009


LOOKING AT THE ubiquitous clocks on classroom walls, many school officials may be wondering whether they will still keep time at the stroke of Y2K. They are no doubt wondering, too, whether computerized attendance and payroll data will drop out of sight. The clocks will probably run as well as ever which means that no two in the same building will ever agree. This matter of keeping time in schools has an interesting dimension when you compare two recent lists. One looks backward in time to the beginning of the century; the other looks forward, presenting a scenario for education in the 21st century. The latter, based on the ideas of the Council of 21, a group made up of leaders from education and business brought together by the American Association of School Administrators (AASA), is certainly radical by our current standards. However, it is the former list that might actually be the more radical document, describing as it does the major events that have shaped education in this century. Imagine trying to predict in 1900 what schooling in the United States would become by century's end. It is doubtful that many of these actual events would have been on any list of predictions, proof that it is very difficult to account for the unpredictable in forecasts of what society, the world, and the schools will be like. The "Top 10 Educational Events of the 20th Century" was compiled by Ben Brodinsky, whose career in educational publishing and journalism spanned half of this century. Writing in EdPress News (volume 63, no. 1), Brodinsky lists the GI Bill of Rights as the major event. At first, this may not seem so momentous, but those who witnessed the influx of serious, older students onto the campuses of colleges and universities following World War II would probably agree about the importance of the GI Bill. It changed higher education from an elitist institution into one accessible to all those who would lead the country in the economic expansion of the second half of the century. It gave them a chance to enter professions that they would never have considered without it, and it made college attendance seem like a natural progression to future generations. According to Brodinsky, nearly 21 million people have benefited directly from this federal program. Desegregation of schools is Brodinsky's pick for the second most important happening in the past 100 years. In 1900, one would have needed to envision a very different society in order to expect this change to happen. Once it did occur, again as a national priority, it challenged both values and law and the hypocrisy of both in a struggle that is still going on. Nevertheless, it was inevitable. One cannot imagine the United States declaring itself a world leader and coping with the rising importance of developing countries and, at the same time, maintaining an education system separated by race. The Brown desegregation decision by the U.S. Supreme Court also laid the groundwork for Brodinsky's third most important 20th-century event, the Education for All Handicapped Children Act, most recently called the Individuals with Disabilities Education Act (IDEA). He doesn't mention it, but the idea that universal education includes all students was also extended to other identifiable groups, including ethnic minorities, language minorities, and females. Again, we haven't worked out all the problems yet, but few today would argue with the need to provide all children and young people with a good education. These events had their origins in midcentury. But the fourth most important event, now taken for granted in American education, took place way back at the beginning of this century. That event was the creation of the American public high school, which at the beginning of the century enrolled only 11% of young people. Although the first public high school opened in Boston in 1821, according to Brodinsky, public secondary schooling was considered a waste of money by most policy makers and taxpayers until well into this century. …


................................................................................................................ iv Acknowledgements .............................................................................................. vi List of Figures ..................................................................................................... xiii List of Tables ...................................................................................................... xix List of Abbreviations ...........................................................................................xx Chapter


The United States Military describes the concept of maneuver as the disposition of forces to conduct operations by securing positional advantages before and or during combat operations. This paper will briefly explore how the concept of maneuver in kinetic operations has evolved over time and how that concept relates to cyber operations and cyber warfare. It will attempt to define what constitutes the principle of maneuver within cyberspace as it relates to the traditional concept of maneuver in warfare and how the unique domain of cyberspace alters this concept. This paper will explore the characteristics of maneuver in cyberspace and the basic offensive and defensive forms of maneuver that have thus far emerged will be identified and analysed. The author will also briefly touch on the issue of sovereignty in cyberspace as it relates to cyber maneuver and attempt to identify how and when the concept of cyber maneuver might cross the line to violate a state's sovereignty. This paper will demonstrate that there is a valid concept of maneuver in cyberspace, and that the stealth and anonymity provided by the Internet allows for blatant acts which, in a kinetic operation, would most like result in open armed conflict.


Text-based conversational Turing test benchmarks for artificial intelligence have significant limitations: It is possible to do well by only faking intelligence, thereby subverting the test's intent. An ideal replacement test would facilitate and focus AI research, be easy to implement and automate, and ensure that human-competitive performance implied a powerful and general AI. The idea in this paper is that general video game playing is one such promising candidate for an improved human-level AI benchmark. To pass such a test, a computer program must succeed in efficiently completing an unannounced and diverse suite of video games, inter-acting with the game only through simulated versions of the same information streams available to a human player; the test is easy to automate but difficult to exploit, and can stress nearly all aspects of human intelligence through strategic sampling of the vast library of existing video games. In this way, general video game playing may provide the basis for a simple but effective benchmark competition for human-level AI.


THE DETECTION of small leaks in large all-metal vacuum systems has long been a troublesome manufacturing problem for which there was no satisfactory.


Abstract Objective To compare estimated levels of psychological distress in the Australian population as measured by online versus face‐to‐face survey methodologies. Method Kessler Psychological Distress Scale scores from a nationally representative online survey of 955 Australians were compared to results from the 2014–2015 and 2017–2018 National Healthy Surveys, which were conducted by the Australian Bureau of Statistics. Results Australians in the online survey reported levels of psychological distress that were significantly higher than those that completed the face‐to‐face National Health Surveys. This difference was greatest among respondents aged 18 to 34-years. Conclusions These results can likely be attributed to the effect of conducting the Kessler Psychological Distress Scale via a face‐to‐face interview versus an online survey. There are compelling reasons to believe that online surveys elicit more honest responses on sensitive issues, while face‐to‐face surveys are prone to social desirability bias. This suggests that Australian psychological distress may have been systematically under‐estimated in previous research.


Susan Howe's late style marks a departure from her earlier work. Two books recently published—The Quarry (New Directions, 2015) and Tom Tit Tot (Museum of Modern Art, 2015) illustrate this point. Whereas Howe's earlier books of critical prose—for example, My Emily Dickinson (1985)—used scholarship to buttress Howe's critical positions and arguments, her new "essays" in The Quarry are more properly understood as poems. When we analyze Howe's meditations on Wallace Stevens, we learn that she identifies with Stevens to create a new poetic hybrid. And the language and rhythm of these new essays is that of a poetic construct. In the same vein, her long poetic sequence, Tom Tit Tot, made up of fragments of other people's writings, the underlying thread being the fairy tale of Rumpelstiltskin (Tom Tit Tot), is a conceptual work that appropriates fragments of other texts so as to create an entirely new angle on the fairy tale and its cognates. Both of these new books show how contemporary technique—facsimile, xerography, overprint, digital processing—can reanimate literary texts and make them new. Howe's austere later writing is perhaps her very finest.


The Principle of Most Significant Relationship is of great importance in the choice of law rules as to international contracts. This paper examines certain preconditions for the application of the MSR principle and gives some comments on the debecage theory of applicable law in order to clarify some problems concerned in the field of contract law.


Duodenal adenocarcinoma (DA) is a rare gastrointestinal malignancy. Due to the low incidence of DA there is limited data reporting patient outcomes following radical pancreatic resection. Large retrospective single and multi-centre studies suggest that lymph node metastasis is an important factor for long-term patient survival following resection. The management of DA has tended to favour aggressive surgical resection with pancreaticoduodenectomy (PD), although a morbidity of up to 50% has been reported, mostly related to post-operative pancreatic fistulas. We assessed the disease-free (DFS) and overall survival (OS) in patients undergoing pancreaticoduodenectomy for DA in our institution.

 We retrospectively analysed all patients undergoing pancreatic resection for DA at our institution between January 2009 – March 2020 inclusive. All DAs were cytologically or histologically proven prior to surgical resection following imaging review in a Hepato-pancreaticobiliary multidisciplinary team meeting. Patients underwent a Whipple's with distal gastrectomy or pylorus preserving pancreaticoduodenectomy (PPPD) based on tumour size and location. Statistical analysis was performed by a Mann-Whitney U test using a p-value significance of 0.05 (SPSS, IBM, USA). DFS and OS curves were presented by Kaplan- Meier survival curves.

 19 patients underwent pancreatic resection at our institution for DA during the study period. 12 patients underwent Whipple's with distal gastrectomy and 9 patients underwent PPPD. The overall postoperative morbidity and mortality was 37% and 5% respectively. R0 resection was achieved in 18 patients (95%). 9 patients (47%) had no nodal involvement. Median follow up was 31 months (range 1-108 months). Median DFS was 17 months but was significantly higher in patients with no nodal metastasis [p < 0.001]. Median OS was 9.5 months for the whole cohort but was significantly higher in the patients with no nodal vs nodal metastasis (60 vs 17.5 months respectively) p < 0.003].

 DA can be resected by PD or segmental resection. PD is favoured due to improved resection margins and overall increased patient survival, despite an increased morbidity. Our series reports comparable morbidity and mortality to the published literature for DA resected by PD. This study reports a 95% R0 resection rate for DA with a 3- and 5-year survival of 50% and 30% respectively. DFS was found to be significantly higher in patients with no nodal disease, despite predominant T4 disease. This series has identified that lymph node metastasis is one of the most important prognostic determinants of long-term patient survival.

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The invention belongs to the field of biotechnology, and particularly relates to endolysin from vibrio parahaemolyticus phage and application of the endolysin. The amino acid sequence of endolysin from vibrio parahaemolyticus phage is all or part of the amino acid sequence shown by SEQ ID No:1. By sequence structure analysis, the enzyme is shown as lyase capable of splitting bacterial cell walls in the phage. The test verifies that the protein formed by the amino acid sequence has relatively good sterilization activity. After the endolysin is expressed and purified by an existing proper expression vector on the market, the endolysin shows an obvious sterilization effect for vibrio parahaemolyticus phage in vitro, and can be used for preparing a vibrio parahaemolyticus fungistat.


Combinatorial increases in programming productivity are possible by the introduction of high level ope rators and operands for composite data structures such as arrays, matrices, trees, record composites, etc. Su ch operators and operands can be composed to generate an infinite variety of virtual reusable components. However, the performance of the code resulting from such compositions is often inadequate because of the cod e fragmentation and delocalization engendered by the building blocks. Attempts to automatically reorgani ze this code to optimize performance using conventional optimization strategies are usually computationally impractical because of the large search spaces engendered. Anticipatory Optimization (AO) is a method for compiling such compositions directly to optimiz ed code without large search spaces and indeed, withou t any search space at all. The keys to AO are 1) distribu ted optimization plans expressed via code annotations a nd 2) transformation-based optimization planning that concurrently reasons over the domain information, t he


Purpose: Anthracyclines effectively treat many pediatric cancers, but their use is limited by cardiotoxicity and new approaches to mitigate anthracycline-induced cardiac damage are urgently needed. Nanoparticle drug delivery is one solution to maintain anticancer efficacy while mitigating both acute and long-term cardiac complications. Additionally, novel treatments are needed to improve cure rates in certain cancer diagnoses that have not seen advancements in decades, particularly Ewing Sarcoma (EWS).
 Experimental Design: We investigated the use of a self-assembling micelle structure composed of myristic acid conjugated to an Apo-A1 mimetic 5A peptide, termed Myr5A nanoparticles (Myr5A NPs). These nanoparticles are transported into cells via the cholesterol scavenger receptor class B type-1 (SR-B1). Doxorubicin (DOX) and the Myr5A NP cannot form a stable micelle due to the hydrophilic nature of DOX, which results in preferential binding to the peptide shell, as opposed to the hydrophobic core. To favor micelle stability, we opted to use the novel, highly hydrophobic anthracyclines valrubicin and AD198 to test the nanoparticle delivery system. The potency of these anthracyclines encapsulated in Myr5A NPs were evaluated in human EWS cell lines with high and low SR-B1 expression via MTT assay. Additionally, 5 mg/kg intraperitoneal injections were administered weekly to 4-week-old wild type C57BL6/J mice and immune compromised homozygous null forkhead box N1 mice (Foxn1null/null mice) over 5 weeks, to assess by echocardiography, acute and long-term cardiac dysfunction.
 Results: Treatment with Myr5A-encapsulated AD198 and Myr5A-encapsulated valrubicin significantly inhibited EWS cell proliferation at concentrations comparable to conventional anthracyclines. Moreover, compared to unencapsulated valrubicin and AD198, encapsulation resulted in a lower IC50 in EWS lines with higher SR-B1 surface expression. By 19 weeks of age, DOX-treated C57BL6/J mice exhibited significantly decreased ejection fraction (EF) compared to PBS control and Myr5A-encapsulated anthracyclines (p<0.05). Additionally, an increase in Left Ventricular Mass (LVM) was observed in all groups except DOX by 19 weeks (p<0.05). Lastly, DOX-treated Foxn1null/null mice showed diminished survival rate compared to all treatment groups, and similar results to C57BL6/J mice in EF and LVM.
 Conclusions: Our results indicate that AD198 and valrubicin, when encapsulated in Myr5A NPs, induce minimal cardiac dysfunction while maintaining antitumor efficacy in EWS tumors. Myr5A NP drug delivery may be a viable option for the treatment of high SR-B1 expressing tumors with a decreased risk of acute and long-term cardiac complications. Future studies will evaluate the drug potency in non-cancer cell lines, such as cardiac fibroblasts and myocytes, and the effects of Myr5A-encaspulated anthracyclines on EWS xenografts and other pediatric tumors.
 Citation Format: Kathryn Crouch, Logan Davis, Nirupama Sabnis, Alexander Pertsemlidis, Laura Rutledge, James Graham, Jason Yustein, Gregory J. Aune. SR-B1-targeted nanoparticle delivery of novel anthracyclines to Ewing's Tumors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 375.


Abstract This article presents the outcome of an empirical study into the background of Italian films that were screened in Flanders between 2000 and 2006. Reconstructing the histories of the films on the basis of in-depth interviews with selected gatekeepers, it also imparts the results of a pilot study on La meglio gioventù, an Italian film that experienced a high level of success in Belgium. Whilst conveying the findings relative to the Flemish market for Italian cinema, I will describe how the industry participants contend with Italian films and how the attributes of imported Italian films are managed by buyers and sellers alike. When cultural products cross borders, their product lives are invariably compromised by the language of these products, their cultural specificity, and the uncertainty of their reception in the importing countries.


10094Background: Insomnia is experienced by up to 80% of cancer patients, and it frequently co-occurs with circadian rhythm disruption. The relationship is reciprocal in that disruption in circadia...


We conduct a test of the CFRP-thin-wall round steel tube concrete axial compression short column,with the confinement index of CFRP as a leading and high steel pipe's radius-thickness ratio,observed it's failure pattern and characteristics of the deformation,and have had the load-strain curve of the CFRP and steel pipe. We analyzed the load-deformation curve of the CFRP-thinwall round steel tube concrete axial compression short column,discussed the influence of confinement index for specimen's mechanical property and ductility,elaborated the failure process which differ from the common CFRP-steel tube concrete axial compression short column. The result shows that: the failure pattern of CFRP-thin-wall round steel tube concrete axial compression short column is steel yield on the radial side caused by the fracturing of CFRP. On the stage of load rising in plastic,CFRP can delay the yield rate of steel pipe,and the CFRP can get a certain mount of plastic,the specimen on this stage possess a certain stiffening characteristics,and concrete filled steel tubular specimens present a yield characteristics. The confinement index of CFRP have a great influence on the specimen's mechanical property and ductility,the influence of the confinement index of the steel pipe is relatively weak.


Gate patterning control for 28nm Fully Depleted Silicon On Insulator (FD-SOI) technology faces several challenges. For lithography and etch , usage of DoseMapper requires extensive and accurate metrology to compute adequate dose recipes. From etch side we will have to control both polysilicon and metal gate CD's. For device integration it will be extremely important to monitor N and PMOS devices and get appropriate gate profiles since transistor morphology is a key contributor to device performances. In parallel of CD control, thin silicon film on top of buried oxide layer will also require a strict control of its thickness. Scatterometry is the only way to get all these informations from a patterned environment [1]. We will show in this paper how scatterometry has been proven to be accurate enough to support the realization of DOE's for metal gate profile optimisation at gate patterning without doing hundred's of TEM. Scatterometry results are correlated to parametric tests and TEM for ultimate validation.


(57) Abstract: The present invention provides polyamines containing urea groups, their preparation, and adhesives, sealants, embedding compounds, their use in the manufacture of moldings or coatings.


We present a III-V/Si hybrid laser using the silicon waveguide TM mode to reduce the propagation loss, backscattering, and two-photon absorption. The TM-mode laser has superior performance than the TE-mode laser.


1024x768 The present study is a descriptive correlational research which seeks to identity the factors affecting the improvement of communication and organizational empathy. The statistical sample included 164 employees of University of Medical Sciences, Ilam, Iran, who were selected according to Cochran's formula. The data were collected through questionnaires and were analyzed in SPSS based on descriptive-inferential statistics including Pearson's correlation coefficient at the level of α=0.05. Factors affecting organizational communication were divided into three groups: human, organizational and communicative. The groups totally covered 9 items. The findings indicated that the three aspects of human, organizational and communication as well as their sub-groups (regardless of directions of communication) affected organizational communication. Normal 0 false false false RU X-NONE X-NONE


3D models play an important role in a wide range of applications from engineering to training, from visualization to entertainment. The formal representation of, and reasoning over, concepts and properties associated with 3D models can contribute to next-generation 3D scene understanding, classification, indexing, and retrieval via 3D characteristics as opposed to keywords of traditional retrieval methods. This paper introduces a novel 3D model indexing method with X3D-alignment, with an emphasis on the representation, annotation, and efficient content-based retrieval of 3D models and their regions of interest from computer animations.


Abstract This study is called correlational research. The types of data are quantitative data. Here, this study aims to investigate the correlation between intrinsic motivation and self-evaluation toward students' reading comprehension. Intrinsic motivation is the performance or action of a task for its own sake. It values rewards acquired through the process of task completion, regardless of any external factors. Self-evaluation is a process through which a task or organization seeks to understand and assess the value of its work. It is an ongoing process and runs a superior sense of the evaluation process. The researcher used intrinsic motivation (IM) and self-evaluation (SE) as independent variables. In addition, reading comprehension is as a dependent variable. The sample of this research is 110 seventh grade students. The researcher conducted this research on the even semester of 2018/2019 academic year at one of state junior high school in Muncar. The students were given a questionnaire about intrinsic motivation (IM) and self-evaluation (SE). They were also given a reading test. In order to attain the objective of the study, the score was analyzed using multiple regressions in SPSS 20. The data analysis proved that intrinsic motivation (X1) is correlated at 0.492 to the students' reading comprehension (Y). It has a medium positive correlation. The self-evaluation (X2) is correlated at 0.362 to the students' reading comprehension (Y). It has a low positive correlation. In addition, intrinsic motivation (X1) and self-evaluation (X2) are correlated at 0.511 to the students' reading comprehension (Y) at a significant level 0.058. Those variables have a medium positive correlation. Furthermore, students who have better intrinsic motivation and self-evaluation, they have better achievement in reading comprehension. Thus, the null hypothesis are not significantly correlated to students' reading comprehension" was rejected and the alternative hypothesis was accepted. The writer hopes that the other researchers will investigate about intrinsic motivation and self-evaluation more comprehensively in order to get a better result for educational field. Keywords: intrinsic motivation, self-evaluation, reading comprehension


This thesis first makes a deep research on routing protocols in real-life scenarios where the location information of mobile nodes is available. Considering the practical mobility characteristics, a new interpolation prediction algorithm of mobile location is proposed to solve the current problem of speed prediction, and also expands the scope of mobility prediction algorithm. After that, a routing protocol based on the mobility prediction is proposed. In spray phase, multiple copies of the message are distributed in a binary tree way, which can improve the transmission performance and effectively control communication overhead. In forwarding phase, when a node carrying a message copy encounters another node, it will carry out mobile location prediction, and forward the message to the node which will be closer to the destination in the future. This routing protocol reduces the complexity of mobile information collection, and solves the classic routing protocol's problem in delivering messages caused by just waiting to encounter the destination. The proposed routing protocol achieves a better performance in the message delivery probability and delivery delay.


Introduction Smartphones are becoming ubiquitous (Smith, 2011), and mobile internet services are extensively used for various sorts of applications (Gerpott, Thomas, & Weichert, 2012), including ecollaboration (Jones, 2012), e-learning (Cheong, Bruno, & Cheong, 2012; Wong, Boticki, Sun, & Looi, 2011), games (Ho & Tu, 2012), and much more. Although technology acceptance and diffusion of innovation are one of the most studied areas in information systems research (Jeyaraj, Rottman, & Lacity, 2006; Rogers, 2003; Venkatesh, Morris, Davis, & Davis, 2003), very little research has been conducted about smartphone applications' adoption (Verkasalo, Lopez-Nicolas, Molina-Castillo, & Bouwman, 2010). One of the major decisions that prospective consumers of a smartphone have to make is choosing its operating system. The decision, which operating system to choose, is based on their own perceptions, as well as perceptions and recommendations of others, while their opportunities to extensively try the devices beforehand are limited. It is important to investigate the perceptions of smartphone holders, who have been using the devices for a while. In order to gain a deeper understanding of the effects of operating systems on users' perceptions of advantages and disadvantages of smartphones, existing users of smartphone devices were selected for this empirical study. Currently, the most prevailing operating systems are Apple's iOS and Google's Android. Therefore, this study compared these two operating systems. There are more factors involved in the selection decision of a smartphone, such as the available content and applications (Laugesen & Yuan, 2010), or ideological considerations, like using free and open source software (FOSS) and open standards (Subramanian & White, 2012). However, these issues are beyond the scope of this paper, which focuses on the perceived advantages and drawbacks of smartphone operating systems by people who have already bought them, and have been using them for a while. This study contributes to the informing science transdiscipline (Cohen, 1999, 2009; Gill & Bhattacherjee, 2009; Gill & Cohen, 2009) by providing insights regarding the effects of operating systems on users' perceptions of their personal mobile information system, i.e., advantages and drawbacks of their smartphone. This empirical study is important, because only a few studies examined the adoption of smartphones, and most of them (e.g., Cheong et al., 2012) focused on smartphone applications, unlike this study that considers the device. Theoretical Context and Hypothesis Development The global research question of this study is whether operating systems affect smartphone possessors' perceptions of advantages and drawbacks of their device usage, when compared with consuming the same services via a computer. This study investigates three specific research questions (RQ), which originate from the global one: RQ1: Which sorts of perceptions of smartphone advantages and drawbacks are affected by its operating system? This question is elaborated in the subsection "general versus operating-system-related characteristics". RQ2: Are there gender differences of smartphone possessors' perceptions of advantages and drawbacks of their device usage? This question is developed in the subsection "gender differences" RQ3: Does the period of possession of the smartphone affect its possessors' perceptions of advantages and drawbacks of their device usage? This question is explained in the subsection "period of possession". General versus Operating-System-Related Characteristics When comparing the consumption of mobile internet services via a smartphone with consumption of the same services via a computer, there are two main sorts of characteristics that should be considered separately: general characteristics of smartphone use, and characteristics that are affected or determined by the operating system. …


Objective—During atherogenesis, macrophages migrate into the subendothelial space where they ingest deposited lipoproteins, accumulate lipids, and transform into foam cells. It is unclear why these macrophages do not remove their lipid loads from the region. This study was aimed at testing the hypothesis that macrophage behavior is altered when membrane cholesterol levels are elevated, as might be the case for cells in contact with lipoproteins within atherosclerotic lesions. Methods and Results—We examined the effects of elevating membrane cholesterol on macrophage behavior. J774 macrophages were treated with either acetylated low-density lipoprotein (ac-LDL) and ACAT inhibitor or cholesterol-chelated methyl-β-cyclodextrin (chol-MβCD) to increase membrane cholesterol levels. Our results show that elevating the membrane cholesterol of J774 macrophages induced dramatic ruffling, stimulated cell spreading, and affected F-actin organization. Cellular adhesion was required for these effects, and Rac-mediated signaling pathways were involved. Additionally, 3-dimensional transwell chemotaxis assays showed that migration of J774 macrophages was significantly inhibited when membrane cholesterol levels were raised. Conclusions—These findings indicate that increased membrane cholesterol causes dramatic effects on macrophage cellular functions related to the actin cytoskeleton. They should provide new insights into the early steps of atherogenesis.


Chabot Horm Res 2006;65:289–294 294 8 Tran JT, Sheth AP: Complications of subcutaneous fat necrosis of the newborn: a case report and review of the literature. Pediatr Dermatol 2003; 20: 257–261. 9 Balazs M: Subcutaneous fat necrosis of the newborn with emphasis on ultrastructural studies. Int J Dermatol 1987; 26: 227–230. 10 Norwood-Galloway A, Lebwohl M, Phelps RG, Raucher H: Subcutaneous fat necrosis of the newborn with hypercalcemia. J Am Acad Dermatol 1987; 16(Pt 2):435–439. 11 Dudink J, Walther FJ, Beekman RP: Subcutaneous fat necrosis of the newborn: hypercalcaemia with hepatic and atrial myocardial calcifi cation. Arch Dis Child Fetal Neonatal Ed 2003; 88:F343–F345. 12 Drut R, Drut RM, Greco MA: Massive myocardial calcifi cation in the perinatal period. Pediatr Dev Pathol 1998; 1: 366–374. 13 Kruse K, Irle U, Uhlig R: Elevated 1,25-dihydroxyvitamin D serum concentrations in infants with subcutaneous fat necrosis. J Pediatr 1993; 122: 460–463. 14 Sabokbar A, Pandey R, Athanasou NA: The effect of particle size and electrical charge on macrophage-osteoclast differentiation and bone resorption. J Mater Sci Mater Med 2003; 14: 731–738. 15 Cranefi eld DJ, Odd DE, Harding JE, Teele RL: High incidence of nephrocalcinosis in extremely preterm infants treated with dexamethasone. Pediatr Radiol 2004; 34: 138–142. 16 Alon US, Scagliotti D, Garola RE: Nephrocalcinosis and nephrolithiasis in infants with congestive heart failure treated with furosemide. J Pediatr 1994; 125: 149–151. 17 Bachrach LK, Lum CK: Etidronate in subcutaneous fat necrosis of the newborn. J Pediatr 1999; 135: 530–531. 18 Rice AM, Rivkees SA: Etidronate therapy for hypercalcemia in subcutaneous fat necrosis of the newborn. J Pediatr 1999; 134: 349–351. 19 Ezgu FS, Buyan N, Gunduz M, Tumer L, Okur I, Hasanoglu A: Vitamin D intoxication and hypercalcaemia in an infant treated with pamidronate infusions. Eur J Pediatr 2004; 163: 163–165.


Song Yu's Gaotang Fu,Shennv Fu,Dengtuzihaose Fu,Feng Fu,Zhaohun have depictded twp types of beautiful women as goddess and folk women.On the surface of the text,Song Yu is good at using beautiful words,wonderful sentences,exaggerated idea and other ways to render the female beauty.On the morality,Song Yu's description takes ethical significance into beauty.On the art,these beautiful women have different artistic features.Song Yu's much attention to beautiful women and wonderful description created the theme of erotic works.


The Fifth generation of mobile broadband (BB) networks, popularly known as 5G, aims to revolutionize different vertical industries, including media broadcasting. Although it remains to be seen the real impact and timescale of the 5G revolution, 5G may represent an opportunity rather than a threat for broadcast (BC), especially when considering new approaches for BC and BB evolving into new converged platforms inter-connecting terrestrial BC and cellular/wired BB systems together [item 1) in the Appendix]. Hybrid BC-BB platforms are already a success in several countries, based, e.g., on HbbTV in EU, hybridcast in Japan and Ginga in Brazil. But the increasing importance of fixed and mobile BB IP delivery for television services, well-illustrated by the new IP-based ATSC 3.0 standard [item 2) in the Appendix] and the on-going DVB-I (Internet) specification, and the fact that the 5G system will support and be interoperable with non-3GPP access technologies, potentially allowing multiple access technologies to be used simultaneously for one or more services, opens the door to new convergence scenarios.


Phishing email detection is a significant threat in today's world. The rate at which phishing are generated are tremendously increasing day by day. It is high time to deploy a self-learning system that gives a time bound detection and prevention of phishing email efficiently. This work proposes a system which uses term document matrix as feature engineering mechanism and classical machine learning techniques for detecting phishing email from legitimate and phishing ones. The system also incorporates the domain knowledge and lexical features as part of feature engineering mechanism. The efficiency of the system is compared using different classical machine learning techniques. Based on the accuracy, we propose the best model that solves the formulated problem efficiently.


. S9 denotes all groups G that possess an ascending invariant series whose factors are one-or two-generated Abelian groups. We are interested in the problem (1): For which nontrivial groups A and B is A wr B in S? (1) has been completely solved by D. Parker in the case where A and B are finite of odd order. Parker's results are partially extended here to cover groups of even order. Our answer to (1) is complete in the case where A is a finite 2-group: If A is a finite 2-group, A wr ß is in S iff B is finite and B/OJB) is isomorphic to a subgroup of a dihedral group of an elementary 3-group. If A is not a 2-group, we offer only necessary conditions on B. Problem (1) is closely related to Problem (2): If F is a prime field or the integers, which finite groups B have all their irreducible representations over F of degrees one or two? It is shown that all finite B which satisfy (2) are S groups; in particular all such B site solvable.


Ten new species of the genus Newportia Gervais, 1847, are described, belonging to the subgenus Newportia Gervais, 1847; Newportides Chamberlin, 1921 and Scolopendrides Humbert & Saussure, 1896. Drawings with of the significant characters for each species are presented. A map shows tipical localities for all known species for Venezuela.


BACKGROUND
The outbreak of coronavirus disease 19 (COVID-19) has caused great concern to public health. Convincing clinical experiences showed that traditional Chinese medicine (TCM) has exhibited remarkable efficacy in the prevention, treatment and rehabilitation of COVID-19.The research on the treatment of COVID-19 disease with TCM mainly focused on the pharmacological effects and mechanistic analysis. However, the pharmacokinetics and potential herb-drug interaction of TCM in the treatment of COVID-19 is currently incompletely clear.

METHOD
This review summarizes the pharmacokinetics and characteristics of cytochrome P450 enzyme (CYP450) metabolism of TCM recommended in the Guidelines for diagnosis and treatment of coronavirus disease 2019 (trial version eighth), and meanwhile analyzes the potential interactions between TCM and western medicine.

RESULTS
The pharmacokinetics of TCM mainly focused on preclinical pharmacokinetics and fewer clinical pharmacokinetics research were reported. When TCM and western are both metabolized by CYP450 and co-administered, a potential herb-drug interaction might occur.

CONCLUSION
Knowlege of the pharmacokinetics and metabolism of TCM is a key to understand rational TCM use of COVID-19 and develop antiviral TCM.


The increasing use of iodinated contrast medium in radiological procedures, especially in coronary angiogram has raised concerns in growing incidence of contrast induced nephropathy (CIN). CIN is the 3 leading cause (1) of acute renal failure in hospitalised patients which can be prevented if adequate preventive measures are taken. The risk of CIN after primary cardiac intervention (PCI) not only extends to patients with prexisting renal failure but also to those with normal baseline renal function. Although there have been many studies on preventive measures on hydration, Sodium bicarbonate, aminophylline and Ascorbic acid, N-acetylcysteine (NAC) has been of great interest due to its low cost and negligible side effects. Evidence for renal parenchymal injury by oxygen free radicals led to the evaluation of effectiveness of antioxidants in prevention of CIN, Nacetylcysteine is essential to reduce morbidity and mortality in this clinical setting. NAC attenuates CIN, owing to its ability to scavenge oxygen free radicals, thereby preventing direct oxidative tissue damage and its ability to counteract dye induced renal vasoconstriction. Use of non-ionic low osmolality contrast media and preprocedural hydration with intravenous fluids both appear to decrease the risk of contrast nephropathy. Recent work suggests that administration of NAC further reduces the likelihood of contrast nephropathy, but other trials have failed to confirm this finding. Hence it has remained controversial till date.


Abstract In 2013, the American Political Science Association (APSA) Task Force on Political Science, Electoral Rules, and Democratic Governance released a report in which the authors say that more than 50 U.S.-based political scientists have been involved in electoral reform processes in the U.S. and abroad since 2010 (Htun and Powell 2013). In this symposium, we give new insights to this topic by offering a view from the outside of the U.S. European and Canadian political scientists who had been invited to give their opinion about the electoral system of their country, and who engaged with politicians, public officials, and national media on the topic, talk about their experience as national experts. They answer two related questions: (1) What do political scientists know about electoral reform that practitioners do not? and (2) Does it make a difference? This symposium gathers their respective contributions to the roundtable. In this introduction, we give a brief overview of the literature on the role o...


Since calcium and fibrinogen are essential cofactors for ADP-induced aggregation, their mechanisms of action were investigated. Aspirin-treated platelets were filtered through Sepharose 2B equilibrated with cation-poor Tyrode's solution. After adding the radioactive compounds at 22, platelets were centrifuged through silicone oil. Trapping was assessed in separate samples with 14C-sorbitoi. Calcium binding was maximal at 1 hr and with 200 uH CaCl2. Two binding sites could be demonstrated on normal and thrombasthenic platelets and on platelets which had lost their ability to aggregate (but not to change shape or promote clot retraction) after treatment with EDTA (8 min, 37°, pH 7.8). ADP did not alter calcium binding in the presence or absence of fibrinogen. Fibrinogen, however, bound to normal gel filtered platelets in the presence of ADP and ionized calcium " but not to thrombasthenic or EDTA-treated platelets or to normal platelets in the presence of EDTA or at pH 6.5. Binding of fibrinogen increased with concentration but saturation was not observed even at physiologic levels. Fibrinogen binding was similar in gel filtered platelets and citrated piatelet-rich plasma. These studies indicate that stimulation of platelets with ADP under conditions favorable to aggregation is associated with binding of fibrinogen but not of additional calcium.


Introduction COPD exacerbations impose a major burden on patients and the NHS. They are often treated empirically with antibiotics and steroids, despite a large proportion being viral induced or non-infective. We hypothesised that incorporation of R-POCTc within our integrated hospital at home service would improve quality of patient care by ensuring delivery of a more personalised management plan whereby treatment was guided by clinical testing. Objectives To investigate whether Home R-POCTc for COPD facilitated: Reduced antibiotic prescribing Avoidance of hospital admission and ED attendance Improved patient experience and quality of life (QOL). Methods 42 patients underwent R-POCTc: CRP, procalcitonin (PCT) (Finecare) and a panel of 12 respiratory viruses and 4 atypical bacteria(BioFire Film Array, Biomerieux Inc.) were testedusing samples taken by nurses in patients' homes and then analyzed by them in a community hub. Outcomes in this patient cohort were compared before and after the implementation of R-POCTc. Patient reported experience measures (PREMs), health anxiety and QOL questionnaires were collected longitudinally. Results Patients were COPD Gold stage C/D, MRC 3, mean FEV1 less than 50% with a mean of 4 exacerbations and 1 hospitalisation in the last year. RPOCTc allowed antibiotics to be withheld in 32 patients who would have received this treatment at their previous exacerbation (figure 1a). A significantly larger number of patients avoided hospital admission (figure 1b). COPD assessment tool (CAT) scores showed that quality of life was significantly higher in the same group of patients after service implementation (mean difference -2.2, p=0.002). Conclusion R-POCTc improves quality of care in severe COPD by delivering a safe, personalised approach, enhancing the patient experience and journey, by home testing and by reducing risks of inappropriate antibiotic prescribing, thereby improving antimicrobial stewardship. QOL was objectively better using R-POCTc. Patients found the support and care provided at home (without recourse to hospital admission) enhanced recovery from the exacerbation. Personalised decision-making gave reassurance to patients and staff. Patient involvement provided empowerment, education and understanding about their condition. This should help address the frequently high levels of anxiety within this group, which can precipitate exacerbations.Abstract S104 Figure 1


Structural loading on a wind turbine is due to cyclic loads acting on the blades under turbulence and periodic wind field. The structural loading generates fatigue damage and fatigue failure of the wind turbine. The individual pitch control(IPC) is an efficient control method for reducing structural loading. In this paper, we present an IPC design method using Decentralized LQR(DLQR) and Disturbance accommodating control(DAC). DLQR is used for regulating rotor speed and DAC is used for canceling out disturbances. The performance of the proposed IPC is compared with CPC, which was designed with a gain-scheduled PI controller. We confirm the effect of fatigue load reduction with the use of damage equivalent load(DEL).


The results of a comparison of the numerical-analytical solution of the Lame problem for a cylinder made of nonlinear elastic material with the solution of the same problem by the finite element method are presented. Calculations are made for the compressible Mooney-Rivlin material and the Murnaghan material. The numerical-analytical solution is based on the use of the semi-inverse method, which is briefly described in relation to the class of problems under consideration; the problem reduces to solving the Cauchy problem for an ordinary differential equation. A finite-element solution was found in a three-dimensional formulation using the Fidesys engineering strength analysis system using 8-node and 20-node elements. The influence of the type of finite elements, material parameters and the magnitude of the applied load on the computational error is investigated.


Atovaquone is a new hydroxy-napthoquinone antiprotozoal agent active against Pneumocystis carinii in vitro and in animal models. The authors report an experience using atovaquone to treat 25 patients with mild to moderate P. carinii pneumonia. Eligible patients were treated for 21 days with 750 mg of atovaquone orally three times daily. Prednisone was added when the P(A-a)O2 gradient was between 35–45 mm Hg. Patients were treated under three treatment protocols. Patients in Group 1 participated in one of two randomized comparative drug trials, designed for patients with and without sulfonamide intolerance. Six of seven patients successfully completed treatment, and one patient discontinued treatment because of an adverse reaction (>5 times baseline increase in transaminase level). Patients in Group 2 were treated with atovaquone for mild to moderate P. carinii pneumonia under a treatment Investigational New Drug protocol because of prior sulfonamide reactions. Fifteen of these 18 patients successfully completed treatment; one died from other complications during treatment and two discontinued treatment for adverse reactions (>5 times baseline increase in transaminase levels, and a diffuse rash). Serum transaminase levels returned to normal at the end of treatment in all patients with elevated levels. All patients demonstrated clinical resolution of their pneumonia and improvement of pretreatment hypoxemia (Group 1: pretreatment PaO2 = 82 ± 14 mm Hg, posttreatment PaO2 = 92 ± 9 mm Hg). Overall, 21 (84%) of 25 patients successfully finished therapy without significant adverse reactions. Atovaquone appears to be an effective and well-tolerated oral treatment for mild to moderate P. carinii pneumonia. The main toxicities appear to be a reversible serum transaminase rise and a nondesquamating rash. Currently, atovaquone should be considered as an alternative therapy for intolerant patients or as salvage therapy.


Through the Eyes of the Employment Manager. Twelve Common Resume Myths. Preparing to Write. Resume Writing--General Comments. The Chronological Resume. Sample Chronological Resumes. The Functional Resume. Sample Functional Resumes. Problem Resumes. Physical Appearance of the Resume. The Cover Letter. Sample Cover Letters. The Top 50 Executive Search Firms.


In voice trunking over ATM (VTOA) technology, the tandem is replaced by three components: trunk inter-working function (T-IWF), control and signaling inter-working function (CS-IWF), and ATM network. This new architecture calls for re-examination of the signaling channel delay issues, which are well-studied and well-specified for TDM networks. In VTOA, the ATM network together with the inter-working functions act as a virtual tandem switching system, which is called "ATM-based distributed virtual tandem switching system". The aim is that the performance of the ATM-based trunking network should be at least as good as the TDM-based network. The cross-office delay budget must be shared among the inter-working functions and the ATM network. Hence, the time for the ATM network to establish a switched virtual connection (SVC) is stringent. In this paper, we propose a simple adaptive SVC caching scheme to offload the high processing capacity burden on ATM switches. After a SVC is established in the usual way for a call, it is not torn down after the conversation is over. Instead, it is kept alive for variable duration (i.e., delayed release) with the expectation that there would be another call request for the same terminating end office during that time. The caching duration is adaptively changed with call arrival rate and call setup delay in the ATM network in order to stay within the delay budget specified by the requirements. The adaptability and the convergence of the algorithm are also shown by extensive simulations related to practical scenarios.


A toxicity test is a test to detect the toxic effect of a substance on a biological system and to obtain typical dose-response data from the test preparation. This study aims to determine the content of secondary metabolites from the aqueous extract and ethanolic extract of gardenia leaves, characterization of gardenia leaf extract, and acute toxicity using the BSLT method against Artemia salina Leach shrimp larvae.Phytochemical screening tests were carried out by the color change method which included the alkaloid test, flavonoid test, tannin test, saponin test, and terpenoid test. Extract characterization tests include determination of water-soluble extract, determination of ethanol-soluble extract, determination of water content, and determination of ash content. Acute toxicity test using the Brine Shrimp Lethality Test (BSLT) method using Artemia salina Leach shrimp larvae.The results of the phytochemical screening test for the aqueous extract of gardenia leaves showed positive results on saponins, while the phytochemical screening tests on ethanol extracts showed positive results on alkaloids, flavonoids, saponins, tannins, and terpenoids. The results of the characterization test on the aqueous extract of gardenia leaves were that the ethanol-soluble extract content was 20.19%, the water-soluble extract content was 23.17%, the water content was 99.13% and the ash content was 0.29%. Meanwhile, in the ethanolic extract of gardenia leaves, the ethanol-soluble extract content was 60.80%, the water-soluble extract content was 57.14%, the water content was 7.87% and the ash content was 3.22%. The results show that gardenia leaves are not toxic with the LC50 value of the water extract of the gardenia leaves is 1399.64 g/mL and the LC50 value of the ethanolic extract of the gardenia leaves is 1080.96 so that it can be used as traditional medicine.


This research was conducted to examine the perception of digital zakat in the scope of Islamic economics from the point of view of sentiment research on Twitter social media users in responding to the development of digital zakat. The method used in this research is a qualitative approach with descriptive statistics from literature studies in the form of 1237 Twitter tweets. Python library software called VADER (Valence Aware Dictionary and Sentiment Reasoner) is used to classify tweets. The sentiment analysis results tended to perceive positive sentiment at 51.7%, neutral sentiment at 28.6% and negative sentiment at 19.7%. The variety of sentiment analysis results reflects the diversity of opinions regarding the progress of digital zakat. The benefit of this study is to contribute literature and considerations in relation to the development of digital zakat as well as identifying shortcomings and threats, such as negative perceptions towards the use of digital zakat. In addition, the objectives of this study also include understanding the positive views, advantages, potentials, and benefits of digital zakat. This research is the first comprehensive research that discusses sentiment analysis on the theme of digital zakat with Twitter tweet data. Suggestions for further research and recommendations are included.


This study aims to clarify differences in parameters based on frequency volume chart (FVC) and on daytime and nighttime urine according to the nocturia frequency, age, and gender.


This is a summary of some of the reports on progress in heavy quark physics presented at the Hadron 2003 conference.


Deployment of novel artificial synapses serves as the crucial unit for building neuromorphic hardware to drive data‐intensive applications. Emulation of complex neural behavior through conventional Si‐based devices requires a large number of elements which increases fabrication complexity and brings challenges of connectivity. Hence, there is a need to investigate alternative material systems and device architectures for emulating richer neural behavior comprising of lesser elements. Herein, a thin‐film transistor‐like synaptic device using all‐inorganic cesium lead bromide (CsPbBr3) perovskite quantum dots (QDs) and amorphous indium gallium zinc oxide semiconductor active material is explored for brain‐inspired computing. The incorporation of CsPbBr3 QDs as a photosensitizer aids in realizing light‐dependent synaptic memory. Furthermore, type II heterostructure can serve as a basis for electro‐optical programming. The proposed artificial synapse demonstrates a materials combination that can decouple optical absorption and charge transport property and provides freedom to tune the spectral region. Harnessing the advantages of novel materials, the devices obey spike‐timing‐dependent plasticity rules, inculcate associative learning and linear nonvolatile blind updates. This architecture paves way for efficient building of neuromorphic hardware elements with facile tunability and tailorable plasticity.


Purpose: The goal of this study is to build a population representative silicone arterial model with lubricated lumen for easy deployment and testing of neuroendovascular devices.

Materials and Methods: We described previously a small batch manufacturing method by infusing silicone into a core shell structure for preparation of patient specific silicone vascular replicas. To evaluate the accessibility for neurovascular device delivery to the anterior intracranial circulation, an internal carotid artery (ICA)–middle cerebral artery (MCA) bifurcation model with representative …


American president Barack Obama visited China from Nov.15-18 in 2009.This article analyzes the related coverage in The New York Times(NYT)from Nov.10-23,and finds that the NYT outlined a picture of dualism by depicting China as a rapidly rising country on economy but stern and inflexible on politics,lacking human rights and press freedom;while criticizing Obama for his weakness of daring not to stick to American core values.Furthermore, this article also analyzes the reasons.


Introduction: Although coronary perforation is a rare
complication observed during intervenetional procedures, it has a
considerably high mortality rate. The prevelance of coronary perforation has
been reported to be 0.20%-0.6%. Its sudden development, the patient's
agitation and development of rapid collapse render intervention difficult.
Materials and Method: The presence of perfusion balloon and covered stent in
clinics is life-saving. In the present study, we retrospectively reviewed 17
cases with coronary artery perforation that were treated between 2009 and 2012.
Of these patients, 10 (58.8%) were men and 7 (41.2%) were women; the median
age was 62.8 ± 8.3 years. The coronary artery perforation resulted from guide
wire in 23.5%, balloon dilatation in 58.8% and stent implantation in 17.6%.
All the lesions were either type B or C lesions. Results: The extensiveness of
perforation was Ellis grade I in 23.5%, grade II in 47.1% and grade III in 29.4%
of the cases. In the treatment of the perforation, polytetrafluoroethylene-covered
stent graft was implemented in 9 (52.9%)
patients, whilst conventional and emergency surgical therapy was performed in 8 (47.1%) patients. Grade
I perforations occurred due to the guide wire and were managed with conventional
therapy (p