Receiving wireless power, in accordance with an embodiment of the invention the device includes a frame that provides a predetermined inner space, a coil provided on an upper portion of the frame pattern, a contact is provided on one side of the frame is connected to the coil pattern and the electrical terminal and the combined with the frame and disposed above the coil pattern includes a magnetic material sheet is as therein defined, and the coil pattern may be provided and integrated with at least one and insert mold the injection of the frame and the magnetic material sheet have.


Therapeutic procedures recommended include miotics (Rychener, I944), hot and cold compresses (Kushner, 1959), and anterior chamber irrigation with proteolytic enzymes (Podos, Liebman, and Pollen, I964; Sinskey and Kricheskey, I962; Scheie, Ashley, and Weiner, 196I; Pierse and Legrice, I964). Sinskey and Kricheskey (I959) observed that neither miotics nor mydriatics had any detectable effect on the absorption of 51Cr. labelled red cells injected into the anterior chamber of rabbits. Cole and Byron (I964) suggested a combination of enzymatic irrigation of the anterior chamber and intravenous administration of urea, and Kwitko and Costenbader (I962) advised intravenous urea in the treatment of every case of hyphaema with a sustained increase in intraocular pressure. Ahuja and Kaothalkar (i 969) discussed the effect of urea, sucrose, sorbitol, and glycerol on the resorption of hyphaema using radioactive blood injected into the anterior chamber of rabbits.


Semi-supervised learning algorithms learn from a combination of both labeled and unlabeled data. Thus, they can be applied in domains where few labeled examples and a vast amount of unlabeled examples are available. Furthermore, semi-supervised learning algorithms may achieve a better performance than supervised learning algorithms trained on the same few labeled examples. A powerful approach to semi-supervised learning, called multi-view learning, can be used whenever the training examples are described by two or more disjoint sets of attributes. Text classification is a domain in which semi-supervised learning algorithms have shown some success. However, multi-view semi-supervised learning has not yet been well explored in this domain despite the possibility of describing textual documents in a myriad of ways. The aim of this work is to analyze the effectiveness of multi-view semi-supervised learning in text classification using unigrams and bigrams as two distinct descriptions of text documents. To this end, we initially consider the widely adopted CO-TRAINING multi-view algorithm and propose some modifications to it in order to deal with the problem of contention points. We also propose the COAL algorithm, which further improves CO-TRAINING by incorporating active learning as a way of dealing with contention points. A thorough experimental evaluation of these algorithms was conducted on real text data sets. The results show that the COAL algorithm, using unigrams as one description of text documents and bigrams as another description, achieves significantly better performance than a single-view semi-supervised algorithm. Taking into account the good results obtained by COAL, we conclude that the use of unigrams and bigrams as two distinct descriptions of text documents can be very effective.


TiO2/ZrO2/SnO2 nanocomposite with large pore is prepared by sol-gel method with Pluronic P123 and Macrogol 20000 as double template. The structure and physicochemical property of the composite are characterized by small-angle powder X-ray diffraction (SAXS), wide-angle powder X-ray diffraction (WA-XRD) and N2 adsorption-desorption. The photocatalytic efficiencies of the product are assessed by monitoring the photodegradation of Rhodamine B (RhB).The results show that the doping of SnO2 retard the crystal phase transformation from anatase-TiO2 to rutileTiO2; the doping of ZrO2 stabilizes the anatase phase, and the phase transformation can be greatly retarded; the materials have relatively regular pores and high specific surface area; two types of pores attributed to the usage of double template; the presence of SnO2 significantly increase the degradation rate; the materials can be used five times without decreasing their photocatalytic capacities significantly.


This article relates to the Observer as a methodological category of semantic analysis. The cognitive model of observation reflects inseparable ties between the Observer and the Observed which make it necessary to give proper consideration to the analytical complex «the Observer + the Observed» while interpreting various aspects of perception presented in lexical semantics.


VERVLOET, R. J. H. M. Morphological and structural constraints on the dynamics of the river basin of the River Benevente Espirito Santo. 2009. xxx f. Dissertation (MA) Faculty of Philosophy, Letters and Human Sciences, University of Sao Paulo, Sao Paulo, 2009. The study of watersheds in the humid tropical environment, has acquired great importance in recent decades due to growing demand for water resources planning. However, many studies have confused the concept of watersheds, believing that this was simply a network of interconnected channels that form the hydrography of the land, thus making it as simple cartographic unit of study. This commonplace is the use of concepts related to the studies of basins, causing serious confusion in the current academic productions. Assuming that the basins are territorial spaces of vertical and horizontal movement of water, the interconnected network of channels, as one of its main elements, we chose the basin of Rio Benevente to study the relationship between the dynamics of this river and its structural and morphological constraints. Based on the method of the Association and indeterminacy in geomorphologic Leopold and Langbein (1970), and through information from the technical and operational procedures of geomorphological partitioning and compilation of data from hydrographic parameters, could find that the sub-drainage systems that make up the total of the hydrographic basin, driven by evolving litoestruturas crystal and the tectonic proterozoico, therefore, the old organization, and that, apparently, show not suffer reactivations modern as to intervene in the evolution of sub-compartments of regional importance and the evolution of the network of river channels. Enough is thus concluded that the processes to fit the drainage, catch river, sectioning of litoestruturas, genesis of knickpoints and evolution of longitudinal river profiles are associated with the dynamic of geomorphic processes differential,under litoestruturas of strong anisotropic nature and complex organization geotectonica. Fact responsible for the diversity of sub-compartments of important configuration and evolutionary dynamics of river systems of differential.


This article examines the Pounds Off Program (POPS) at Oral Roberts University from 1976 to 1978. POPS was a mandatory weight-loss regime for fat students who were required to lose a certain amount of weight in order to maintain their status at the university. The program generated national controversy in 1977 when some fat students allied with the American Civil Liberties Union (ACLU) to sue the university for discrimination. The article argues that the POPS reflected many U.S. citizens' views that there was a direct relationship between body weight and piety. The cooperation between the fat students and the ACLU also demonstrated the fluidity of U.S. society on the eve of the culture wars.


Under three-dimensional drainage conditions, the consolidation of saturated cohesive soil is affected by the shape and size of the loading area on the surface. When there are differences in area and shape between the field loading test and practical engineering, the results from the loading test cannot accord with the practical ones. It must be modified. According to the three-dimensional consolidation theory, a modified formula for calculating the degree of consolidation is presented in this paper.


Given a Tonelli Hamiltonian H:T*M → ℝ of class Ck, with k ≥ 4, we prove the following results: (1) Assume there is a critical viscosity subsolution that is of class Ck + 1 in an open neighborhood of a positive orbit of a recurrent point of the projected Aubry set. Then there exists a potential V : M → ℝ of class Ck−1, small in the C2 topology, for which the Aubry set of the new Hamiltonian H + V is either an equilibrium point or a periodic orbit. (2) For every ɛ > 0 there exists a potential V : M → ℝ of class Ck−2, with ‖V‖C1, for which the Aubry set of the new Hamiltonian H + V is either an equilibrium point or a periodic orbit. The latter result solves in the affirmative the Mañé density conjecture in the C1 topology. © 2015 Wiley Periodicals, Inc.


Dearterialization should reduce arterial overflow to haemorrhoids. The purpose of this study was to assess the topography of haemorrhoidal arteries.


This study examines the writing strategies employed by a group of undergraduate French majors while composing in both the L1 (English) and the L2 (French). A descriptive study points to the existence of distinct writing strategies based upon the language of composition.


Abstract Older immigrants in affordable senior housing face a unique set of challenges due to their demographic, social, economic, and cultural diversity. Existing knowledge about health among this unique but increasing aging subgroup population is extremely limited. Focusing on older immigrants subgroups (Asian and Russian older adults) in affordable senior housing in St.Louis, MO, this study aimed to examine to what extent different ethnic minority elders' health varies by their uses of services available in the housing. Data came from the survey interviews at a subsidized independent senior housing in St. Louis (n=136). Hierarchical multiple regressions were used to examine ethnic differences in self-rated health and the role of services for the health of low-income ethnic minor elders in senior housing. Compared to the non-immigrants (White/African older adults), Asian (b=0.67, p<.05) and Russian residents (b=0.89, p<.05) were likely to have lower self-rated health. Interestingly, for both ethnic groups, they report a better self-rated health when they use supportive daily service (i.e. e.g. meal delivery, transportation, housekeeping and others) (b= -0.84, p<.05 for Asian, b=- 0.90, p<.05.for Russian) and social service (e.g. recreational, wellness, and exercise programs) (b= -0.73, p<.05 for Asian, b=- 0.83, p<.05.for Russian). Our findings point to an important role of services for the health of low-income ethnic minor elders in senior housing. As the first attempt to examine services that explicitly focus on ethnic minority elders, our study provides meaningful implications for future research on the health and service needs for older immigrant populations in senior housing.


A study involving drug treatment services in Australia has found a strong level of support for greater consumer participation in the planning and delivery of these services. It is found that the benefits of inclusion include improvements in the quality of health care; improvements in health outcomes; more appropriate public policy and better use of public funds among other things.


This article examines the features of implementing EU values in transitional democracies, with a focus on Ukraine and the Republic of Moldova. It aims to explore the challenges and successes of these countries in adopting European values and democratic principles, as well as to analyse the impact of such implementation on their social and political development.
Drawing on existing literature and case studies, the article explores the historical and political experience of Ukraine and the Republic of Moldova on the way to the implementation of EU values, including their transition from Soviet-style governance to democratic systems.
The analysis highlights the role of political instability, corruption, judicial reforms, and cultural factors in shaping the implementation of EU values, as well as the importance of civil society and EU engagement in promoting democratic reform. In particular, the article emphasizes the role of mentality in shaping public attitudes towards democracy and the rule of law. In particular, the article emphasizes the role of mentality in shaping public attitudes towards democracy and the rule of law. Overall, the article argues that successful implementation of EU values is crucial for the future of democracy and economic development in Ukraine and the Republic of Moldova. And, that a comprehensive and multi-faceted approach is necessary to overcome the challenges that stand in the way.
The Russian–Ukrainian war, which began in February 2022, has become a global challenge and a threat to the entire democratic concept of Europe. Today, it is clear that the military conflict in Ukraine is a fierce confrontation between democratic and traditional values. Accordingly, Ukraine's victory will be a fundamental determinant in strengthening and developing European values in the region. That is why, realising this, the EU and most democratic countries are trying to support Ukraine in this struggle in every possible way.


Based on a bulk flotation-separation flotation process,the experiment for comprehensive recovery of copper,cobalt and iron from a polymetallic copper sulfide ore in Sichuan was performed.The results showed that the process can obtain a copper concentrate with grade of 22.41% Cu and recovery of 91.32%,and a cobalt concentrate with grade of 0.53% Co and recovery of 56.22%,then iron was recovered from above mentioned flotation tailings,and obtained iron concentrate contained 64.49% Fe with recovery of 38.04%.


This article outlines the low-temperature cofired ceramic (LTCC) technology, from its historic evolvement to the basics of dielectric material properties and manufacturing process with emphasis on the design concept of multilayer LTCC RF and microwave embedded passive devices and modules. A detailed table containing most of commonly seen passive components is provided with layouts of their high-frequency circuit models (Table 4 in the article).

Keywords:

LTCC;
ceramic material;
RF circuits;
laminated waveguide;
microwave circuits


Unlike other components of the Renaissance Venetian economy, such as maritime trade, shipbuilding, glassmaking, and the woolen industry, the silk industry has been largely neglected by historians: a somewhat puzzling neglect, for that industry was viewed by contemporaries as a major player in the economy, enjoyed an enviable international reputation, and employed at its peak a highly skilled labor force of several thousands. In this richly textured, exhaustive study covering three centuries and based on a prodigious amount of archival research, Luca Molà has filled a large gap and has thus greatly expanded our knowledge of a multifaceted Renaissance economy.


An apparatus for measuring the conversion efficiency η and several further key properties of thermoelectric generators is presented. To achieve highest reliability and accuracy the crucial determination of the thermal energy that is supplied to the generator is done by an absolute method, i.e. by measuring the electrical power that is dissipated in a thermally guarded resistive heater. The accuracy of this method was carefully verified with a traceable calibration standard. The data evaluation is discussed for test measurements of a high efficiency Bi2Te3 module and compared to results that are estimated from the material properties. Excellent accuracy, consistency and reproducibility of the data are found, which makes the measurement a sensitive and reliable tool for the development of thermoelectric generators.


Fermilab Main Injector is upgrading the accelerator to double the beam intensity from 24e12 protons to 48e12 protons, which brings the accelerator into a regime where electron cloud effects may limit the accelerator performance. In fact, an instability that could be caused by electron cloud effects has already been observed in the Recycler [1, 2]. Secondary Electron Yield (SEY) is an important property of the vacuum chamber material that has great influence on the process of building up free electrons. The Main Injector of the Fermilab accelerator complex offers the opportunity to measure SEY and conditioning effects in the environment of a running accelerator, since samples of these materials are located at the beampipe wall. The SEY of stainless steel (SS316L) and TiN coated SS316L in the proximity of the proton beam were measured and compared. A series of simulation studies of electron cloud build up were done for the Main Injector and Recycler using the code POSINST. Parametric studies were done to determine the maximum electron density vs. peak SEY at different beam intensities in the Fermilab Main Injector. Threshold simulations of electron cloud density versus SEY were extended from Main Injector to include the Recycler Ring [3]. It was found that the electron cloud density around the beam depends on bunch location within the bunch train. SEY MEASUREMENT The Secondary Electron Yield (SEY) measures on average how many electrons are emitted when one electron hits the beam chamber surface. SEY is generally dependent on the incident electron energy, E, and the incident angle, θ. The SEY of different materials and coatings has been studied for many years; however, the effect of the accumulated dose under actual accelerator conditions has only been studed recently [4]. SEY Test Stand The SEY measurement stand was originally designed and built by Cornell. Modifications were made to adapt it to the Main Injector, reduce background, and improve signal level for the Main Injector tunnel conditions [4, 5]. The measurement stand has two different arms so that two samples can be exposed to the same dose for comparison. The arms are protected by faraday boxes to eliminate leakage current. Each sample is a small curved piece that sits on the vacuum chamber wall. They are retracted from the vacuum chamber on an electrically isolated arm during measurements. Two Kimball Physics ELG-02 electron guns were installed and are directed towards the sample at a 15 Figure 1: The SEY test stand. angle, which will increase the measured SEY by 1% compared to normal incidence, according to the Furman-Pivi probabilistic model [6]. The electron guns scan over an energy spectrum of 45 eV to 1545 eV with a 1 mm diameter spot on a 3 × 3 grid. A Keithley 6487 pico-Ammeter is used to indirectly measure the SEY of the sample. A bias voltage must be applied during measurements and the picoAmmeter is also used to apply this bias voltage. A typical measurement generally takes 6 to 8 hours, which includes transportationof the DAQ-control computer, equipment set-up and warm-up and then the actual measurement. The test stand vacuum vessel is groundedduring measurements. The gun was set to to deliver 0.5 to 1.0 nA beam at 300 eV. The primary current Ip is measured by applying a +150 V bias voltage that recaptures all secondary electrons. The total current It is measured by applying -20 V that repels all low energy secondary electrons. Then the secondary emission current is given by ISEY = It − Ip . The SEY can be calculated by the following equation. SEY = ISEY Ip = It − Ip Ip (1) Leakage Current Due to the low signal current measured, the bias voltage induced leakage current can cause a very high background during a measurement. The leakage current can reach as high as tens of nano-Amperes and must be compensated when calculating the SEY from the data. High leakage current generally occurred when the ceramic (used to isolate the vacuum vessel from the sample) got wet due to moisture from the surrounding atmosphere, or there were excessive vibrations around the testing stand, or current leakage from the wire to the faraday box. The following modifications were made to control the leakage current: 1. Implementation of a faraday box. Proceedings of IPAC2015, Richmond, VA, USA MOPMA039 5: Beam Dynamics and EM Fields D06 Coherent and Incoherent Instabilities Measurements and Countermeasures ISBN 978-3-95450-168-7 629 Co py rig ht © 20 15 CC -B Y3. 0 an d by th er es pe ct iv ea ut ho rs 2. Implementation of a nitrogen system to keep the ceramic dry. 3. Better isolation of wires from the faraday box. The leakage current generally takes 2 to 5 minutes to reach a steady level, so before a measurement it is necessary to wait for the leakage current to settle. Recently, the leakage current during measurements have been around 300 pA with a variation of 20%. SEY Measurement Results Two sets of Main Injector SEY measurements have been taken to monitor changes with beam exposure. Incident energy 0 50


The results of an empirical study of international competition for the UK machine tools market are presented. The research focuses on the comparative marketing strategies and organizations of a matched sample of British, German, U.S. and Japanese subsidiaries competing for customers in the UK market. The most striking contrast is between the Japanese subsidiaries on the one hand, and their British and U.S. rivals on the other. The German subsidiaries fall in-between the two. In terms of emphasis on marketing performance and a willingness to take a laid-back attitude to short term profits the German subsidiaries were closer to the Japanese approach. In terms of organization, control and reporting procedures they were more akin to the other Western competitors than their Japanese rivals.


Restoration of endodontically treated teeth is important for the success of endodontic treatment. In full coverage restorations, maximum amount of tooth structure is compromised, so as to conserve the amount of tooth structure partial coverage restorations, can be preferred. This case report is on fabrication of a conservative tooth colored restoration for an endodontically treated posterior tooth. A 22-year-old male patient presented with pain in the mandibular left first molar. After endodontic treatment, composite material was used as postendodontic restoration. The tooth was then prepared to receive a ceramic onlay and bonded with self-adhesive universal resin cement. Ceramic onlay restoration was periodically examined up to 2 years.


Landslides are one of the most severe and pernicious natural phenomena which occur on Earth. They particularly occur in sloped regions where the integrity of the topsoil of the land has been compromised. The reasons for this are multifaceted, depending on the lithography of the region in question. A landslide can be triggered by intense inundation, cloudburst, earthquakes, deforestation, which at times can be a consequence of urbanization, amongst other factors. They have a detrimental effect on the geography, local economy of the region they occur in and cause immense monetary loss as well. There is a need for timely detection of landslides for establishing correct preventive measures and technological advancements, especially in the field of deep learning are being used for the same. In this paper we present an approach based on Convolutional Neural Networks, using median pooling for feature reduction applied on a dataset with highly inclusive features like vegetation index, water-based index, temperature wind speed, precipitation etc. The architecture of the models is discussed and the preprocessing of features is done as well. We finish with a discussion on model performance and possible improvements.


--In this paper, based on the materials between the years of 2001-2012 in Shandong province, we estimated the level of the fusion between informationization and industrialization, calculated the integration index, and quantitatively reflected the integration development level of the fusion between informationization and industrialization in Shandong Province. And then, through the establishment of VAR model, we empirical analyzed the dynamic fusionrelations in Shandong province. Finally, we proposed countermeasures and suggestions for the deep integration of informationization and industrialization in Shandong Province, in order to promote the realization of Shandong Province's development objectives, and also promoted the transformation of Shandong Province from a big economic province to a strong economic province to achieve leapfrog development of social productive forces, and provided valuable decision-making recommendation. Keywords-Informationization; Industrialization; The fusion of informationization and industrialization;The VAR model I. RESEARCH BACKGROUND There are many theoretical studies on the integration of the informationization and industrialization and they are mainly focused on the relationship of informationization and industrialization, the connotation of the integration, the mechanisms, and promotion policies and so on. For example, Zhou Zhenhua ( 2008 ) , Tong Youhao ( 2008 ) , Li Jian ( 2010 ) , respectively from different perspectives describe and analyze the connotation of the integration of informationization and industrialization [1][2][3]; An Xiaopeng ( 2008 ) adopts the perspective of the global industrial revolution and elaborates the integration[4]; Xu Jun ( 2008 ) conducts a theoretical analysis on the influencing factors of the integration, and brings forward some corresponding strategies[5]; Jin Jiangjun ( 2009 ) establishes a theoretical model to study the theoretical system of the integration[6]; Wang Jinjie ( 2009 ) comes up with an analytical research on China's countermeasure for integration[7]; Wang Xiwei, etc. ( 2010 ) start from the connotation of the integration and reveal the maturity models of both the development of informationization and industrialization, based on this basis , they also construct a system model of the key elements of the integration.[8] Ji Desheng, etc. ( 2012 ) explore the related issues on the deep integration in China's high-tech zone[9]. Based on the contents of the existing researches, they mainly focus on the theoretical issues of the integration and empirical analysis on the national level, but empirical analysis on the provincial and municipal levels is not enough. Therefore, this paper is based on the existing researches between the year of 2001-2012 to estimate Shandong Province's level of integration index since the last 12 years, and reflect the level of development of integration in Shandong Province, and then, through the establishment of the VAR model, empirical analysis and dynamic relationship of integration in Shandong Province is analyzed, while at the same time, combines the study with economic sense. II. THE MODEL AND METHOD A. Two fusion level measure method Two chemical fusion levels ultimately reflected in the development of informatization and industrialization level, the two fusions the deeper, the higher the level of informatization and industrialization. Therefore, we still adopt the method of informatization and industrialization International Conference on Advanced Information and Communication Technology for Education (ICAICTE 2014) © 2014. The authors Published by Atlantis Press 65 level, respectively, measure to reflect the two fusion levels. 1) Method to measure the informatization level Informatization index is used to calculate the different social, national or regional level of informatization index. This paper uses model of informatization index of the Japanese Telecommunications and economic comparison of authority (RITE) proposed, the model from four secondary indicators of the amount of information, information equipment, the rate of communication subject level, information coefficient to measure the different social stages, different countries or areas of informatization development degree, under the two-level index, set up 11 tertiary indicators. In combination with the practical situation of our country and the status of the realistic society, we improved the RITE model, remove some indicators that does not reflect the current social reality, and increase some index can reflect the characteristics of the current social development. The improved RITE model contains four secondary indicators and 14 tertiary indicators, as shown in tableI. TABLEI EVALUATION INDEX SYSTEM OF INFORMATIONIZATION LEVEL Index1 Index2 Index3


Background: Common variable immunodeficiency (CVID) is one of the most prevalent symptomatic primary immunodeficiencies (PIDs), which manifest a wide clinical variability such as gastrointestinal (GI) disorder.Patients and Methods: A total of 240 patients with CVID were enrolled in this study. The patients were evaluated for demographic data, clinical manifestations, and immunologic profile.Results: In demographic data, the frequency of consanguinity and mortality rate were higher in patients with GI manifestation than those without GI manifestation. History of GI manifestations was evident in 147 patients (61.3%). The most common GI manifestation in patients with CVID was chronic diarrhea (29.6%). The prevalence of GI disease was 59 of 102 (57.8%) in female patients and 88 of 138 (63.8%) in male patients. The frequency of recurrent infection was higher in patients with GI manifestation than in those without GI manifestation. Also, CVID patients with GI manifestations had lower WBC and CD4+ T cells than patients without GI manifestations.Conclusion: CVID patients are at increased risk of infectious conditions in the GI tract; hence GI manifestations are one of the most important presentations in CVID patients which can appear as a first manifestation or appear during the course of disease.


Digalo is a graphic-based software tool for supporting collaborative argumentation and structured discussion. It has been developed in the framework of the DUNES project (IST-2001-34153, http://www.dunes.gr ). Using Digalo consists of synchronously co-creating maps built of written notes inside different cards (represented by diverse geometrical shapes), as well as using different arrows to represent various types of connections between the cards or contributions. These 'cards' and 'arrows' represent the ontology or the "grammar" of the discussion, which constrains but also facilitates and promotes the discourse [1,2] by guiding the learners to use specific speech acts and raising their awareness to their discursive roles, thus encouraging a certain type of discussion, such as critical dialogue.


Objective To observe the Shenlingbaizhu Powder for the Treatment of Chronic Obstructive Pulmonary Disease(COPD) respiratory muscle fatigue patients.Methods 78 cases of COPD in remission in patients with respiratory muscle fatigue,were randomly divided into observation group and control group patients with the control group given conventional treatment,observation of traditional Chinese medicine group were scattered Shenlingbaizhu oral treatment.Comparison of two groups of patients with respiratory failure,the incidence and remission rates of dyspnea,arterial blood gas before and after treatment of PaO2 and PaCO2,pulmonary function in accounting for expected value of FEV1 and FEV1/FVC percentage changes.Results The incidence of respiratory failure 30%,dyspnea 70% remission rate are higher(P0.05).Observation group after treatment,arterial blood gas PaO2 was increased in the trend,PaCO2 downward trend,in FEV1 lung function is expected to account for the percentage of the value and FEV1/FVC values after treatment were significantly higher than(P0.01),two groups have significant difference.Conclusion Application of Shenlingbaizhu Powder for the Treatment of COPD patients with respiratory muscle fatigue is an effective method of traditional Chinese and western medicine,it is worth to further promote clinical.


The research presented in this article is a wear volume analysis of the effects of silver nanoparticles in a polyethylene-glycol lubricant (PEG). The ball-ondisk method was used to perform the tests and a surface profilometer was used to analyze the amount of wear produced by this nanolubricant. The results showed that with the addition of silver nanoparticles, the wear was reduced significantly in comparison to a control sample without any nanoparticles. This is in contrast to some of the nanoparticles which can actually increase the wear when added to a lubricant.


This letter tries to enhance the presented information in the Unworthy peer review process and publishing method,1 which has been recently published by this journal.


Laboratory for Intelligent Processes and Systems The University of Texas at Austin, Austin, TX 78712 barber~maii.utexas.edu This research analyzes the performance of individual agents and groups of agents in different Decision-Making Frameworks across a variety of situations. A DecisionMaking Framework (DMF) specifies how a set of agents interacts when determining how a set of goals should be achieved (Barber and Martin, 2001). A Decision-Making Framework is (1) the decision-making control set which agents make decisions about the goals, (2) the authorityover set which agents must carry out the decisions, and (3) the set of goals under consideration. The experiment domain is naval radar interference management, where each agent has one goal, "Minimize system radar interference." Each agent controls the radar frequency on a simulated ship and attempts to choose frequencies that are not being used by other radars in the system. The performance metric is the mean interference of all agents in the environment. The roles agents play in DMFs are Decision-Making Interaction Styles. Master agents decide how to achieve goals for themselves and Command-Driven agents; Consensus agents collaborate equally to decide for the group; and Locally Autonomous agents decide alone. The graph below reflects an analysis of how combinations of Decision-Making Interaction Styles and Decision-Making Frameworks affect the performance of individual agents and groups of agents in accomplishing an inter-dependent set of goals in a shared simulation.


A computer-controlled densitometer for data acquisition and high speed analysis of photographically recorded optical emission spectra has been developed. The instrument scans and digitizes spectra and stores the data sequentially in computer memory. A high-resolution linear measurement transducer mounted on a Jarrell-Ash densitometer monitors the plate position as the spectrum is scanned. The transducer measurement is accurate to within 0.001% over a range of about 340 mm on a glass photoplate. Computer algorithms for locating and identifying peaks and for calculating the wavelengths of spectral lines from their positions in the spectrum are described. With the use of a calibration curve based on the measured positions of three known spectral lines, the wavelength of any spectral line can be determined to within 0.005 nm, and the transmittance of a peak in the recorded spectrum can be measured to within 1%. The wavelengths and transmittances of all detectable spectral lines in the digitized emission spectrum are determined in less than two minutes.


The utility model relates to a feed type cutting machine of a circuit board, which can ensure the quality of a circuit board after a circuit board is broken. The utility model comprises a machine table, a movable feed group, a control structure and a fixing feed group, wherein, both sides of the upper end of the machine table are provided with horizontal frames provided with saw-shaped belt pulleys which are driven by a motor; the lower edge of the horizontal frame is provided with a linearising slide rail; the control structure is arranged on the other side of the horizontal frame; the movable feed group comprises a horizontal n-shaped seat of which the upper end is provided with clips clamped on the saw-shaped belt pulley; the lower part of the horizontal n-shaped seat is pivoted with a round feed disc; the fixing feed group is arranged on the lower edge of the machine table and corresponds to the round feed disk of the movable feed group.


Problem statement: A two-dimensional wave prediction model along the best track of Typhoon Linda 1997 was interested to study the impact of typhoon wind-wave characteristics. The dynamical wave model with deep water condition was used to predict the wave height (Hs) of Typhoon Linda before and after entering into the Gulf of Thailand (GoT). Approach: The standard one-way nested grid for a regional scale of the third generation WAve Model Cycle 4 (WAMC4) is scrutinized in the present study. This model is enabled to solve the spectral energy balance equation on a coarse resolution grid in order to produce boundary conditions for a small area by the nested grid technique along the best track of typhoon. The model takes full advantage of the fine resolution wind fields in space and time produced by the available US Navy Operational Global Atmospheric Prediction System (NOGAPS) model with 1° resolution. The nested grid application was developed in order to gradually increase the resolution from the open ocean towards the South China Sea (SCS) and the Gulf of Thailand (GoT) respectively. Results: The model results were predicted at five stations which were before and during the typhoon entering into the GoT. The wind speeds of the stations 1-5 were in ranges of 5.14-29.81, 4.11-28.27, 0.51-24.67, 0.51-31.35 and 0.51-33.41 m sec-1, respectively. While the Hs of these stations were found in ranges of 0.54-2.99, 0.68-2.85, 0.11-1.57, 0.12-2.92 and 0.09-2.76 m, respectively. The model results were compared with buoy observations at Ko-Chang and Rayong locations in the GoT which were obtained from the Seawatch project. The comparison of those results at Ko-Chang and Rayong showed the percentage errors of 11.20 and 15.12% respectively. Conclusion: The model results presented the relationship of typhoon wind-induced ocean wave at five stations along the best track. The tendency of the Hs from the model in the spherical coordinate propagation with deep water condition in the fine grid domain was in good agreement with the Hs from the observations.


This paper expounds the present development of coal washing techniques, illustrates the basic principles and technical performances of new techniques and new equipment, looks forward to the developing trends of washing coal industry, and advances some problems needing solution in the coal washing industry.


A supersonic underwater pulsed acoustic source has been developed at Loughborough University. A 120 kV magnetic core transformer drives electrical breakdown which acts as an acoustic source. The paper will present the design of the system and source, the diagnostic methods used to study breakdown, including an ultra-fast camera, acoustic diagnostics, and analytical techniques employed. The main results will be presented and discussed.


Exonuclease activity has been measured in preparations of both enzymes. The activity associated with DNA polymerase a requires denatured DNA, Mg2+ and is ATP-dependent. The polymerase b-associated nuclease requires denatured DNA and Mg2+ or Caz+. Studies of the distribution of these enzymes during the cell cycle have shown that extracts of cells harvested at the time of nuclear DNA synthesis (Chiang & Sueoka, 1967) have DNA polymerase b as the predominant DNA-synthesizing activity, whereas DNA polymerase a is the major activity in cells harvested at a resting phase of growth. The two major DNA polymerases of Chlamydomonas reinhardii therefore seem to differ in physical and enzyme properties and in the time of appearance during the vegetative cell cycle.


This invention provides a surface treated electrolytic copper foil, which has a low profile on an equal or higher level as compared with a low-profile surface treated electrolytic copper foil which has been supplied on the conventional market and is small in waviness which affects the linearity of wiring, and a process for producing the same. In the surface treated electrolytic copper foil, on the face of adhesion to an insulating layer constituent material, the maximum level difference of elevation of waviness (Wmax) is 0.05 mum to 0.7 mum, the maximum difference of elevation of irregularities (PV) is 0.05 to 1.5 mum, and the surface roughness (Rzjis) is 0.1 mum to 1.0 mum. The electrolytic copper foil used in the production of the surface treated electrolytic copper foil is produced by electrolysis under electrolytic conditions of current density on at least two different levels from continuous first step electrolysis to nth step electrolysis, using a sulfuric acid-based copper electrolysis solution, prepared by adding 3-mercapto-1-propanesulfonic acid or bis(3-sulfopropyl)disulfide, a quaternary ammonium salt polymer having a cyclic structure, and chlorine, and a cathode having a small surface roughness.


Automated quantitative (i.e. stochiometric) analysis of tissues is of eminent importance in the understanding of all interactions between cells in their natural environment. In tissue cytometry a solid trigger is necessary in order to unequivocally differentiate between cellular and non-cellular events. This can be best performed by nuclear staining. Aim of this study was to analyze a brain tissue section by laser scanning cytometry (LSC) in order to depict the threedimensional distribution of nuclei in the tissue. To this end the section was measured in several foci and different nuclei detected in several depths of the tissue were assigned to the respective layer. Frozen sections of formalin-fixed rat or human brain tissue (120μm thickness) were incubated with propidiumiodide (PI) (50μg/ml) and covered on slides. For analysis by the LSC propidiumiodide was used as trigger. After a first analysis focussed on the top of the tissue, the focus was adjusted in 30μm steps deeper into the tissue. Per analysis data of at least 50,000 cells were acquired. After finishing measurements from all depths of the field were merged, i.e. data were combined into a composite data file. With the special features of the LSC it was possible to develop a method depicting the threedimensional distribution of the nuclei in solid tissue sections. LSC can be useful tool for this relatively new field of solid tissue cytometry termed tissomics. After evaluation of methods like this, so far not available data can be analysed for diagnostic purposes. By these studies we intend to demonstrate the power of the LSC for the routine pathological use. This should add up to the bright versatility of applications for the LSC as a cytometric instrument suitable for high throughput and high content analysis.


In the framework of the isomonodromy deformation method, we present a constructive procedure to obtain the critical behaviour of Painleve VI transcendents and solve the connection problem. This procedure yields two- and one-parameter families of solutions, including trigonometric and logarithmic behaviours, and three classes of solutions with Taylor expansion at a critical point.


This symposium proposes that Participatory Quantitative Ethnography (PQE) is an important new strand of research for the QE community to develop. This paper introduces the participatory research values motivating PQE, outlines contributions from symposium speakers explaining the importance of PQE from different perspectives, before closing with a set of research questions that motivate a research agenda. It is hoped that this symposium may spark fruitful conversations and collaborations that advance PQE concepts, methodologies


Using high density ZnO:Al2O3 (AZO) target (94%) and without introducing any reaction oxygen, (001)-oriented transparent conductive AZO thin films are prepared by rf planar magnetron sputtering deposition on soda-lime glass. The structural, electrical and optical properties of the films deposited and annealed at different conditions are characterized with various techniques. The as-deposited and post-deposition annealed thin films have highly c-axis-orientated growth with hexagonal structure. Samples deposited at below 360°C are very smooth with spherical grains about tens nano-meters, the crystallization has been improved with vacuum annealing. The experimental results show that AZO thin films with optical transmittance of above 85% at wavelength of 550 nm and electrical resistivity of 10-4 Ωcm order were achieved by deposition at substrate temperature of 360°C and subsequently annealed at 450°C for 2 h in vacuum pressure of 10-5 Torr. With increase of the deposition temperature or post-deposition annealing in vacuum, the carrier concentration of AZO thin film increases, and the absorption edge in transmission spectra shifts toward the shorter wavelength side (blue shift).


An automatic detection system based on machine vision is designed to measure the verticality of elevator guide rail more effectively.A verticality measuring robot for elevator guide rail moves along the rail with a vertically fixed lighten ring.Canny transform is used to extract the elliptical edge points acquired by a video camera.Then ellipse parameters are fitted.The relationships between lighten ring geometrical parameters and ellipse parameters are derived.So its geometric center and the normal vector are determined.The changes in the center of the lighten ring reflect those in the verticality of elevator guide rail,and the changes of the angle between normal vector and the vertical reflect the distortion direction of the guide rail.Experimental results show that the proposed system can measure the deformation of the guide rail easily and accurately.


This study estimates the amount of willingness to pay of the general public by applying the contingent value method to the Korea Program for International cooperation in Agricultural technology(KOPIA), a representative project of the Rural Development Administration. Prior to measuring the amount of willingness to pay for the KOPIA project, a survey of the perception of agriculture and rural areas and respondents' basic perception of public development assistance showed a positive perception of official development assistance in general. In particular, many respondents said that aid from the international community in the past contributed to Korea's economic and social development along with the importance of the international community helping the poor in underdeveloped countries. As a result of estimating the acceptance probability regression model by including the public awareness as a variable, the higher the income of the respondents and the more positive the perception of public development aid, the higher the amount of willingness to pay. The average annual payment amount per household derived from the acceptance probability regression model was estimated to be about 30,729 won.Based on the results of this analysis, several policy implications related to the public development aid policy of Korea were presented. ■ keyword :∣Agricultural ODA∣KOPIA∣Contingent Valuation Method∣Willingness To Pay∣ 접수일자 : 2020년 12월 30일 수정일자 : 2021년 02월 15일 심사완료일 : 2021년 02월 18일 교신저자 : 문광민, e-mail : email@example.com 조건부가치측정법을 활용한 공적개발원조의 경제적 가치 추정: 농촌진흥청 해외농업기술개발사업(KOPIA)을 중심으로 549


The freeze–thaw (F-T) cycle of the active layer (AL) causes the "frost heave and thaw settlement" deformation of the terrain surface. Accurately identifying its amplitude and time characteristics is important for climate, hydrology, and ecology research in permafrost regions. We used Sentinel-1 SAR data and small baseline subset-interferometric synthetic aperture radar (SBAS-InSAR) technology to obtain the characteristics of F-T cycles in the Zonag Lake-Yanhu Lake permafrost-affected endorheic basin on the Qinghai-Tibet Plateau from 2017 to 2019. The results show that the seasonal deformation amplitude (SDA) in the study area mainly ranges from 0 to 60 mm, with an average value of 19 mm. The date of maximum frost heave (MFH) occurred between November 27th and March 21st of the following year, averaged in date of the year (DOY) 37. The maximum thaw settlement (MTS) occurred between July 25th and September 21st, averaged in DOY 225. The thawing duration is the thawing process lasting about 193 days. The spatial distribution differences in SDA, the date of MFH, and the date of MTS are relatively significant, but there is no apparent spatial difference in thawing duration. Although the SDA in the study area is mainly affected by the thermal state of permafrost, it still has the most apparent relationship with vegetation cover, the soil water content in AL, and active layer thickness. SDA has an apparent negative and positive correlation with the date of MFH and the date of MTS. In addition, due to the influence of soil texture and seasonal rivers, the seasonal deformation characteristics of the alluvial-diluvial area are different from those of the surrounding areas. This study provides a method for analyzing the F-T cycle of the AL using multi-temporal InSAR technology.


Women Artists in the Age of Reason: Art and Criticism in the 1960's in Portugal This article discusses the new status of women artists in Portugal in the 1960's based on the works of the most significant artists (Paula Rego, Helena Almeida and Lourdes Castro) and on their appraisal by the critics. A real transformation occurs: the attitude of these women changes and the barriers that used to confine them to a particular type of art – female art – are broken. At the critic's level, the paternalistic and discriminatory attitude is overcome, and the turn is to more impartial criteria and less gender prejudice. The article establishes the contrast between the female art, classified by critics in the first half of the twentieth century as naive, lyrical, sensitive and clearly solar, and an art of reflexive and experimental nature, made in the years of 1960's by women with critical and conceptual ability. Key-words Women Artists (in Portugal), Art Criticism (in Portugal), 1960's, Paula Rego, Helena Almeida Resume Femmes artistes a l'âge de la raison : art et critique dans les annees de 1960 au Portugal Le nouveau statut des femmes artistes dans les annees 1960 au Portugal est analyse a partir des œuvres des artistes les plus significatives (Paula Rego, Helena Almeida e Lourdes Castro) et de leur reception critique. MULHERES ARTISTAS NA IDADE DA RAZAO. ARTE E CRITICA NA DECADA DE 1960 EM PORTUGAL


Ovarian cancer is a cancer that begins in an ovary. It results in abnormal cells that have the ability to invade or spread to other parts of the body. The p63 is a homologue gene of the tumor suppressor p53. p63 appears to be important for the development and differentiation of reproductive epithelium and interacts with p53 in human tumorigenesis. This study presents the immunoexpression of the p63 in malignant epithelial ovarian tumors. We evaluated the p63 immunoexpression in 34 ovarian malignant tumors a) using a Polyclonal rabbit antihuman antibody (Biogenex, AM418-5M).


This work describes an analysis of ground penetrating radar (GPR) measurements at frequency range of 1.7-2.6 GHz to get a relationship between attenuation and density for nine road pavements slabs with different densities. There are about two different frequencies had been tried. The method is simple, fast, contact less and accurate way to determine the density of road pavement. The most important parameter that used in this project is density where it can be used to determine the compressive strength of road pavement. In laboratory, the measurement system consists of a signal generator (250 kHz-3 GHz) as a source, spectrum analyzer (100 Hz-8 GHz), directional coupler with adapter and horn antenna. The first part of the measurement system setup is to determine the amplitude of transmitted wave (received signal strength). A few of received signal strength and attenuation for nine pavement slab samples were taken at two different frequencies. The GPR mixture model has been used to produce the simulation data and has been compared with measurement data. An instantaneous method for measuring the density of road pavement in wave propagation was developed by using microwave transmission/ reflection technique and free space method at two frequencies. The MATLAB software is used to analyze the measurement and simulation data and also for the graphs comparisons. The relative error between measurement and simulation were calculated. The results from the GPR measurement were used and were elaborated in data statistical analysis.


We present a new iterative algorithm for 3D reconstruction under constraints from a limited number of radiographic projections with adjustment of the constraints during the iterations. The first step of the algorithm is a classical iterative reconstruction ART type method (Algebraic Reconstruction Technique) which provides a rough volumic reconstructed 3D zone containing a flaw. Then this reconstructed zone is modelled by a Markov Random Field (MRF) which allows us to estimate some 3D support and orientation constraints using a Bayesian restoration method. This fundamental step is an important one in the sense that it allows the introduction of local geometric a priori knowledge concerning the faults. The next step consists in reintroducing these strong constraints in the reconstruction algorithm. Few iterations of the algorithm are necessary to improve quality of the reconstructed 3D zone. Simulated radiographic projections allow the performance of the algorithm to be evaluated


TheCellprocessor offers substantial computational powerwhichcanbeeffectively utilized onlyifapplication design andimplementation aretuned totheCell architecture. Inthis paper; weexamine application characteristics which facilitate efficient useoftheCell processor; andthose which present obstacles toit. Moreover; weconsider possiblesolutions designed tomitigate inefficiencies. Thetarget application inourstudy istheGROMACSmolecular dynamics package. Wehaveaccelerated themost-often used compute-intensive kernel while maintaining theconstraints imposed bythestructure ofthesurrounding program. The significant contribution ofthis paper istheconsideration of thekernel inthecontext ofacomplex end-to-end application, withirregular dataandcodepatterns, rather thanan isolated kernel code. Forthis challenging scenario, ourresults showa2Xspeedup versus hand-tuned VMX/SSEcode running onhigh-end PowerPCandx86uniprocessor machines.


Communities of soil invertebrates were studied in 4 types of tundra ecosystems on Spitsbergen (Hornsund area) during the vegetative season of 1989. Taxonomic composition, density and biomass of soil fauna were evaluated in the sites along a gradient of increase in the biogenic impact of bird colonies, i.e. in polygonal tundra, mossy/lichenous tundra, Calliergon stramineum moss association, and mossy associations near a colony of Little Auks (Alle die). Average total biomass of soil invertebrates increased in this site sequence from 1.1 to 25.0 g wet weight x m "2 (mainly due to collembolans and nematodes). Seasonal dynamics of all groups of soil meso- and macrofauna (Nematoda, Enchytraeidae, Aranei, Acarina, Collembola, Coleoptera, Diptera larvae) is presented and discussed.


This thesis is a first-principles theoretical investigation of solid materials with high degrees of anharmonicity. These are systems where the dynamics of the constituent atoms is too complex to be ...


The charge capacitance of metal containing complexes are studied. For molecules with multiple bonding between the metal atoms it is found that the charge capacitance is correlated to the maximum bond order, natural bond order, and to some extent the effective bond order. Furthermore the charge capacitance of some methylidene metal dihydride complexes are studied. These molecules have agostic interactions of varying strength, and it is concluded that this strength is very well reflected in the charge capacitances of the systems. In accordance with the definition of agostic interactions it is therefor concluded that the charge capacitance holds information about the strength of covalent interactions. The effect therefore on the agostic interactions upon substitution of one of the hydrogen atoms with fluorine in the methylidene metal complexes is studied, and found to reduce the agostic interactions. It is also demonstrated that there is an agostic interaction in an ArCrCrAr complex. The distance dependence of the charge capacitance is also discussed. (C) 2008 Wiley Periodicals, Inc. Int J Quantum Chem 109: 618-628, 2009 (Less)


In modern energy management systems (EMS), there are two types of measurement data collected by the SCADA (supervisory control and data acquisition) system, namely, status data of breakers and switches, and analog data of real and reactive power flows, injections, and bus voltages. The status data are used to determine real-time topology of the network. The analog data are used to determine line and transformer loading and voltage profile. These data are noisy due to measurement errors, communication noise, missing data, etc. In addition to simple checking of the analog data locally, in most modern EMS, state estimation is used to process these data globally to correct errors in the raw analog measurement data. In this paper, the use of global information in state estimation to correct errors in the direct measurements of the status data is proposed and conditions for detectability of errors are analyzed. The telemetered data of breaker and switch status are processed in the EMS computer to determine the present network topology of the system, and this function is called network topology processor. Errors in status data will show up as errors in the network topology. Sasson et al and Dy Liacco et al used a tree search algorithm for the network topology processor. The method is widely used in practice. Bonanomi et al proposed a sequential search method through the network graph. Recently Lugtu et al suggested the approach of using state estimation results for topology error detection.


Alright kids, this is the column where you write in with the lurid
details of your personal lives, and I put them on the Internet for
everyone to snicker at. But also, I give you a free Tarot reading, so
there's that.


This paper aims to prove the growth in the use of social networks by companies in recent years.
More and more consumers are looking for companies that maintain a permanent contact with the customer and especially where he can consult the opinions of other customers. The goal is also to show that with the passage of time companies have the perfect notion that this happens, and therefore, bet on social networks in order to be able to match the expected and keep up with the competition. Having said this, there is also a sub-thesis, in order to prove that companies really have this notion.
To do this, 100 companies were randomly surveyed from various parts of the country, including islands, which answered a total of 10 multiple-choice questions and allowed certain satisfactory conclusions to be drawn, of which, the most important were that almost 40% of the companies analyzed did not have social networks 5 years ago. This is a significant number given that currently around 97% of companies already own them. It is also important that most companies note that they have gained more customers, and consequently, more profit thanks to their bet on social networks. Last, but not least, another significant conclusion is that companies are 100% aware that more and more social networks are used by themselves and that customers prefer that they have them, which is what they come against my sub thesis.
I was very surprised by the feedback I received from all the companies, and I had the notion that social networks that I did not consider so relevant to a company are definitely the most used, as is the case of YouTube. Also note that the idea that he personally had, that a company dedicated to the industry does not have as much concern with social networks, nor will these make a difference in the opinion and captivation of customers is completely wrong! Industry companies are also affected by the new technologies, and many of them made me arrive that noticed a difference in their customers from the moment they created them.


Abstract Not Available – First paragraph follows:
Controlled fermentations in wine are under study using special equipment designed to control the temperature, pressure, type and rate of gas or gases sparged into fermenters, and rate and duration of stirring or pumping-over, and allow the submerging of red grape skins for color extraction. For critical work with various yeasts, the equipment can be sterilized under steam pressure. Control instruments record gas flows, pressures, temperatures, and carbon dioxide and oxygen content of gases. Two of these fully controlled fermenters of 25-gallon capacity have been in use for several years. Ten smaller units, each of 7-gallon capacity, are being assembled and will be fully equipped and available to enlarge the area of study within a few years.


The invention relates to a ground source heat pump unit capable of preventing valve leakage. The ground source heat pump unit comprise a refrigerating or heating circulation device, first to fourth pipelines, first to eighth branch pipes, an air-conditioning system water supply pipe and water return pipe, an underground system incoming water pipe and outgoing water pipe, air-conditioning system and underground system circulation water pumps and eight conversion valves, wherein a check valve is mounted at the part, located at the downstream of each conversion valve, on each of the first to eighth branch pipes. The ground source heat pump unit provided by the invention has the beneficial effect that as the check valve is connected in series at the downstream position of each conversion valve on each of the eight branch pipes which are connected among a condenser, a condenser, and the air-conditioning system and the underground system, pressure difference between two sides of the conversion valve can be effectively reduced, and thus the phenomenon of water leakage at the edge of a valve plate on the conversion valve does not occur. In addition, as the water leakage phenomenon can be reduced, the air-conditioning system does not need ceaseless water replenishment, and thus an energy conservation effect is good.


We show that the family of maximal fixed-cost codes, with codeword costs defined in a right-cancellative semigroup, have biproper trellis presentations. Examples of maximal fixed-cost codes include such "nonlinear" codes as permutation codes, shells of constant Euclidean norm in the integer lattice, and of course ordinary linear codes over a finite field. The intersection of two codes having biproper trellis presentations is another code with a biproper trellis presentation; therefore "nonlinear" codes such as lattice shells or words of constant weight in a linear code have biproper trellis presentations.


A monitoring program was conducted to assess emissions control performance for sulfur dioxide and nitric oxides. The collected data are interpreted. Desufurization rated from 75 to 90 percent while nitric oxides only slightly higher than expected. 3 refs.


The mechanical environment strongly influences many cellular behaviours and responses such as spreading, adhesion, migration, proliferation, differentiation and apoptosis (Lauffenburger and Horwitz 1996; Engler et al. 2006; Dieterich et al. 2008; Trepat et al. 2009; Rørth 2011;). This has been extensively reported for a single cell (motility, random walk and division), for the interaction between two cells (cell-to-cell contact and chemotaxis) or at the tissue level (morphogenesis or tumor progression). For example, many experiments produce valuable observations on single-cell migration on a substrate or on collective migration and these works widely use traction force methods. The values of forces exerted by the cells on the substrate were then estimated by coupling microscopy and inversion procedures (Sabass et al. 2008; Ambrosi et al. 2009). Interesting results have also been found regarding the influence of the substrate rigidity and its anisotropy on cell motility (Lo et al. 2000; Saez et al. 2007; Trichet et al. 2012). Other works focused on cell division and enlightened the association between the division orientation and mechanical efforts (Reffay et al. 2011). All these works are concerned with the study of chemical and physical phenomena arising at different scales (filopodia, cytoskeleton and tissue), and consequently with mechanotransduction, referring to the many mechanisms by which cells convert mechanical stimulus into chemical activity. To better understand the relationships between mechanical and biological effects, some authors have developed models at the cell scale and performed numerical simulations to predict collective effects (Drasdo and Höhme 2005; Peyroux and Pattana 2007; Basan et al. 2011; Vermolen and Gefen 2012). Most of these models can be marked as discrete mechanical models, as distinct from classical continuum mechanics.


The energy fed by active galactic nuclei to the surrounding diffuse baryons changes the latter's amount, temperature, and distribution; so in groups and in member galaxies it affects the X-ray luminosity and also the Sunyaev-Zel'dovich effect. Here we compute how the latter is enhanced by the transient blastwave driven by a shining quasar, and is depressed when the equilibrium is recovered with a depleted density. We constrain such depressions and enhancements with the masses of relic black holes in galaxies and the X-ray luminosities in groups. We discuss how all these linked observables can tell the quasar contribution to the thermal history of the baryons pervading galaxies and groups. Subject headings: cosmic microwave background galaxies: clusters: general quasars: general


Abstract Timberlakena Pate (1939) is reviewed. The subgenera Mohavena Pate (1939), Riparena Pate (1939) and Timberlakena are raised to generic rank and redescribed. Relationships between the three genera are discussed. Ten new species are described: Mohavena bajaensis, M. emmarieae, M. ericalleni, M. utahensis, M. villegasi, Riparena maculifrons, Timberlakena alboclypeata, T. eburnea, T. hirsuta and T. vitellifrons. A new key to the genera of Ammoplanina and keys to the species of Mohavena, Riparena, and Timberlakena are provided. Faces of male and female specimens and forewing venation of each species are illustrated, as well as a habitus photograph of two species of Mohavena.


Motion dictates that the spatial structure of natural image sequences is highly structured over time. In principle, knowledge of this spatiotemporal regularity, combined with local estimates of image structure and velocity, could be exploited by the brain to construct a forward model describing the likely future pattern of visual input. We have recently proposed that predictive signals generated from a drifting sinusoidal grating stimulus interfere with visual input in adjacent regions of space, resulting in a pattern-specific modulation of contrast sensitivity (Roach et al 2011, Curr Biol21 740–745). Detection thresholds are reduced for targets with a spatial form consistent with continuation of the moving pattern (constructive interference) but increased for targets that are inconsistent (destructive interference). To gain a more detailed understanding of the underlying mechanisms, here we extend our examination of these effects using contrast discrimination, equivalent noise masking and contrast matchi...


Homogeneous hydrogenation of 2-phenyl-3-methyl-2-butenoic acid derivatives in the presence of a catalytic amount of such chiral phosphine-rhodium complexes as Rh/(R)-BINAP, Rh/(R)-, or (S)-Cy-BINAP, Rh/(R)-p-tolyl-BINAP, and Rh/(R)-p-methoxy-phenyl-BINAP afforded the corresponding phenylacetic acid derivatives in high enantiomeric excesses and in quantitative chemical yields. The optically active phenylacetic acid derivatives are useful intermediates of agrochemicals and pharmaceuticals.


In regrouping sculptures and drawings by nine representatives of the "new British sculpture", Grant Marchand comments the insertion of drawing in sculpture. Biographical notes. 16 bibl. ref.


To help you find by enhancing the function of a photo-reactive fluorescent mounting material and placeholder in vivo clips quickly and easily the exact location of body treatments target areas to improve the accuracy of the procedure surgery to minimize treatment after the side effects caused by excessive cutting the fluorescent indication clip is disclosed. A vacuum fluorescent display clip for surgery according to the present invention, and a clip body having self-check character (擴 開 性), is provided at the rear end of the clip body the external force from the position that is attached to the fluorescent display and a fluorescent display portion including a photo-reactive fluorescent material by a sliding movement as a clip body can include tightening the tightening portion to the distal end of the pulmonary clip body. Clips, fluorescence, ring laser, position indicating


Objective  Oral malodor is now generally accepted to be the main cause (about 90%) of bad breath. Bacterial formation of the volatile sulfur compounds hydrogen sulfide (H2S) and methylmercaptan (MM, CH3SH) within the oral cavity is the main cause of oral malodor. The objective was to study the occurrence and cause of the less well-known extra-oral halitosis.

Methods  We investigated the mouth- and nose-breath of 59 subjects complaining of bad breath and visiting our bad breath clinic. The methods used were gas chromatography and organoleptic scoring (OLS).

Results  Six of 59 patients (10 %) were found to have extra-oral halitosis. The concentrations of H2S and MM in mouth-breath of patients with extra-oral halitosis were very low and below critical odorous levels. H2S and MM were absent in nose-breath of all patients. The concentration of dimethylsulfide (DMS, CH3SCH3) in mouth- and nose-breath in the six patients with extra-oral halitosis amounted to 1.57 ± 1.31 (s.d.) and 1.64 ± 1.29 nmol l−1 (range: 0.50–4.50), respectively, compared to 0.29 ± 0.19 and 0.21 ± 0.12 nmol l−1, respectively, in patients with oral malodor. The critical odorous concentration of DMS is about 0.5 nmol l−1. Simulated DMS gas-mixtures had the same smell as observed in the extra-oral halitosis patients. In these six patients good to perfect correlations were found between the OLS of mouth- and nose-breath (simple correlation coefficient r = 0.840, P < 0.05), between mouth-OLS and the concentration of DMS in mouth-breath (r = 0.794, P < 0.05) and in nose-breath (r = 0.824, P < 0.05) and between nose-OLS and the concentration of DMS in mouth-breath (r = 0.963, P < 0.001) and in nose-breath (r = 0.955, P < 0.001). A perfect correlation was obtained between mouth- and nose-DMS (r = 0.994, P < 0.001), indicating that DMS does not originate in the mouth . The origin of DMS must be found elsewhere, most probably in the blood.

Conclusions  About 5–10% of patients with chronic halitosis has extra-oral halitosis. In all patients with extra-oral halitosis seen thus far, DMS was always the cause of bad breath. Other causes known, such as trimethylamine in the fish-odor syndrome, are very rare.


Perinatal exposure to Dutch background dioxin levels is rather high. Studies of calamities have shown that dioxins negatively influence the respiratory system. It was hypothesized that perinatal exposure to background dioxin levels leads to lung suboptimality, probably through developmental interference. This study aimed to assess lung function in relation to perinatal dioxin exposure. Spirometry was performed in 41 healthy children (aged 7‐12 y, mean 8.2 y) with known perinatal dioxin exposure. The ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1/FVC ratio) was determined. A complete medical history was taken. The prenatal exposure ranged from 8.74 to 88.8 (mean 34.6) ng TEQ dioxin kg fat−1, measured in breast milk. The postnatal exposure ranged from 4.34 to 384.51 (mean 75.4) ng TEQ dioxin. Twelve children had to be excluded. A significant decrease in lung function in relation to both prenatal (p= 0.045) and postnatal (p= 0.0002) dioxin exposure was seen in the 29 non‐excluded children. A clinical association between chest congestion and perinatal dioxin exposure was seen.


Introduction: PIGN gene is crucial in regulating mitotic integrity to maintain chromosomal stability and prevent MDS leukemic transformation and progression. Alternative Polyadenylation (APA) regulation and 3' RNA cleavage are 2 known vital processes in cellular DNA damage response to maintain genomic stability. NUDT21 gene encodes protein that is one subunit of the cleavage factor Im complex required for 3' RNA cleavage and APA processing. Although PIGN gene has six potential polyadenylation sites, the exact role of NUDT21 product on PIGN expression regulation has not been illustrated before.
 Methods: At first, we analyzed NUDT21 gene expression profile in AML, MDS, and normal control specimens and to plot the relationship between NUDT21 gene expression status and patient survival length from 5 datasets. We also used correlation regression analysis method to predict the gene expression correlations between NUDT21 gene and PIGN gene. Then, we used Caspas9 technology and vector overexpression technology to knockout or overexpress PIGN in HEK293 cells; RNA interference to knockdown the NUDT21 gene in HEK293, HL60, K562, THP-1,SKM-1 and MUTZ-1 cells. MTT and CCK8 methods were used to evaluate cell proliferation. Meanwhile, cell cycle, apoptosis, Reactive Oxygen Species (ROS) and GPI-anchored proteins (CD55, CD59, and CD235) expression profiles were evaluated by flowcytometry; Immunofluorescence experiment, RT-PCR were used to evaluate the impact of NUDT21 gene knockdown on PIGN expression. in vivo mice siRNA interference tests were conducted to verify the impact of NUDT21 knockdown on PIGN gene expression. RNA-Seq & Dapars analyses were conducted on mRNAs from 3 cell lines with various PIGN gene expression status to observe the effects of NUDT21 knockdown on PIGN 3'UTR processing.
 Results: NUDT21 expression increases in AML and high-risk MDS. NUDT21 expression level is negatively correlated with overall survival. NUDT21 knockdown decreases cell proliferation but increases cell differentiation via prolonging G1 phase, decreasing S phase, and increasing apoptosis. NUDT21 knockdown increases cell membrane GPI-anchoring proteins (CD55, CD59, and CD235) expressions; increases ROS and Caspas3 expressions but decreases CyclinD1 expression. NUDT21 knockout can increase PIGN expression, but PIGN expression status has no impact on NUDT21 expression. RT-PCR and WB results showed that NUDT21 knockdown can increase TP53 expression but decrease p21 expression. in vivo mice siRNA interference tests confirmed that NUDT21 knockdown increases PIGN gene expression. The RNA-Seq/Dapars analyses results showed that 3'UTR of PIGN transcript was significantly shortened and PIGN expression increased after NUDT21 knockdown.
 Conclusion: NUDT21 modulates PIGN gene expression through APA mechanism. PIGN polyadenylation may regulate cell proliferation status via modulating cell cycle and apoptosis.
 Citation Format: Jeffrey J. Pu, Fanggang Ren, Na Zhang, Shuo Li, Lan Zhang, Eric Miller, Guirong Wang, Hongwei Wang. NUDT21 regulates PIGN through APA mechanism to affect the progression of MDS and AML. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 4741.


This study is to investigate the capability of producing lignin-based phenol-formaldehyde adhesive (LBPFA) with lignin derived from coir pith collected in the Mekong Delta, Viet Nam. The LBPFA synthetic process underwent non chemical modifications to minimize petrochemicals and energy. Effective factors as reaction time, reaction temperature and various lignin contents of phenol substitution were examined. Physical, chemical and thermal properties containing formaldehyde content, viscosity, solid content, Fourier transformed infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), tensile strength, tensile modulus and tensile strain were conducted. LBPFA was successfully synthesized at various levels of lignin contents substituting for phenol. The LBPFA's parameters were in accordance with GB/T14372-2006 standard. The optimum reaction time, reaction temperature and lignin replacement content for LBPFA synthesis process were identified at 180 minutes, 900C and 40% wt/wt, respectively. The LBPFA showed the highest dry and wet tensile strengths of 14.42 MPa and 7.66 MPa on wooden boards compared to corresponding figures of commercial resin with 2.98 MPa and 0 MPa, respectively. For plywood, bending strength shown in LBPFA and commercial adhesive were 15.97 MPa and 20.16 MPa, respectively.


Strengthening troops equipment support training is the essential channel to improve troops equipment support ability.With the development of our army weapon equipment and the publishment of new training program,it has important significance to study the characteristics,requirements and systems of troops equipment support training for improving equipment support training quality and promoting equipment support ability.


multi-phasic area that it compels the interest and attention of a variety of professions and disciplines. In one way or another it has been of concern to such fields as physical education, psychology; psychiatry, neurophysiology and optometry. In fact, some aspect of motor learning can be regarded as playing a very significant part in a!most any endeavor of human concern. The branch of motor learning under consideration in this report is learning through motor activity and, specifically, children's learning basic skills and concepts in reading and language through movement-oriented experiences. In the field of physical education, when we speak of learning through motor activity, we refer to things that children do in order to learn. Hence, as far as the physical educator is concerned, motor learning activities derive from basic physical education curriculum in the three broad categories of game activities, rhythmic activities and self-testing activities. For this reason we can also refer to motor activity learning as the physical education learning medium. The Use of the Active Game Learning Medium in the Reinforcement of Reading Skills With Fourth Grade Children JAMES H. HUMPHREY, Ed.D. University of Maryland '


The electromagnetic response of a buried conductor is a complex function of the currents induced and channeled into the conductor from the currents flowing in the background media. The ration between the channeling and induced currents is basically deterrnined by the currents in the background half-space that are available for channeling and on the magnetic fleld on the conductor. In order to "see" the target the secondary fields must exceed some threshold value which is dependent on the layered background response and on the source receiver configuration. To compare objectively the detection efficiency of various source receiver configurations we express the responses in terms of the ratio of the secondary field to the field from the background media. This ratio is called the anomaly index, Al. Using the Al to compare different source receiver configurations energizing the same target provides a completely general way to compare the performance of any EM system in either time or frequency domain or to compare between the two domains. The concept of the Al is used to compare normal incident plane waves, a infinite line, a grounded electric dipole (of variable length) and a horizontal loop (of variable side length) over a thin rectangular sheet buried in a conductive half-space. The Al is computed in both time and frequency domain for a whole range of source-receiver parameters. In general we flnd that the Al for EM systems working in the time domain is larger than for systems working in the frequency dornain. The main reason for this is that frequency domain systems has to "see" the target in the presence of the primary fields from the source whereas the primary fields by nature is absent for time domain systems. Furthermore, it is found that for a vertical sheet, whîch is used in this demonstration, the Al for the honzontal transient fields from the horizontal loop source is substantially larger than for the vertical fields (which is the response usually measured). NTRODUCTION In the literature there has been exhaustive studies of the basic response of a variety of subsurface targets in both time and frequency domain. An excellent review is given in the SEG volume "Electromagnetic methods in Applied Geophysics" (Nabighian (ed.), 1988) where a logical grouping has been in chapters dedicated to sounding methods (deterniination of conductivity vs. depth), profiling methods (with a variety of source-receiver configurations) and finally to uniform field niethods such as magnetotelluric and VLE By and large these studies have focused on specific systems in common use for exploration but there has been littie comparison of the relative response of different systems to common targets. In this presentation we describe a generalized approach for comparing the response of conductive bodies to exeitation by dipole, line and uniform incident fields in both time and


By orthogonal experiment, the sequence of technological parameters of friction welding effecting the strength of the welding joint is friction pressure,upset pressure and friction time.These provide important reference for establishing technological parameters of friction welding in practice.


Research on the prescription of 0.5% emamectin micro-emulsion was introduced,and effect of solvents,surfactants,cosurfactants and water quality on the physical stability of product was discussed.The chemical stability was tested and the quality index was obtained.


Historians understand the importance of language. In the 1980s, the discipline took a sharp linguistic turn, as many social historians trained in the 1960s and 1970s renounced cherished ideas about social class and material life, and moved boldly toward a language-centered cultural history. This shift toward linguistic analysis was particularly notable in my own field—the French Revolution—where self-described "revisionist" historians abandoned Marxian social interpretations of the Revolution to pursue the study of political culture. The result was a highly creative body of work, which claimed that what was modern about the French Revolution was not the seizure of power by a rising capitalist bourgeoisie (this was the old Marxian interpretation) but, rather, the dynamic ways in which revolutionaries constructed a radically new political culture. Much of that culture was the product of novel discourse, as words like "la nation," "le citoyen," and "la révolution" took on new, highly charged political meanings. As Roger Chartier argued at the time, the systematic redefinition of such words reflected an intellectual process by which revolution became thinkable and therefore possible.1


This qualitative study is based on the solutions offered by the students of the "Action Research in Education" course within the scope of the pedagogical formation certificate program at Atatürk University Faculty of Education during a 10-minute presentation in the activity called "one solution to one problem." The data collected from the presentations were subjected to content analysis, and sentences were selected as the unit of analysis and tabulated. Subsequently, with the application of a scale developed by the researcher to the same students, two problems, which were not studied sufficiently during the presentations and that the researcher and students agreed were highly critical, were identified. An open-ended scale was applied to the same students about the problems of interruption/overlap and being unfriendly / speaking rudely, and the solution proposals developed by prospective teachers were analyzed by using the descriptive data analysis technique. It was determined that the prospective teachers had a certain awareness of these problems and could produce solutions that can be adapted to the education system. We believe that the study is also important in that it reflects the perspectives of prospective teachers who are important stakeholders of education.


In this response, I suggest that the focus of "emotion" researchers should be more on striving to develop a science of brain and behavior than on deciding what is the proper status of emotion. Because structure and function are closely intertwined in biological systems, advancing our understanding of complex behaviors will necessitate researching their brain substrates.


This study examines how the age at which children enter Head Start affects their academic and behavioral outcomes. Data from the National Longitudinal Survey of Youth are incorporated to analyze the progress of 1,553 Head Start children. The research examines outcomes through assessments conducted at ages 5–6 and at ages 11–12. The results suggest that the measured outcomes vary with complicated interactions among age at Head Start entry, maternal education levels, and maternal verbal test scores. In many cases, early age of entry is estimated to improve outcomes for children whose mothers have low education and test scores.


This paper addresses the linear placement problem by using a spectral approach. It has been demonstrated that, by giving a more accurate representation of the linear placement problem, a linear objective function yields better placement quality in terms of wire length than a quadratic objective function as in the eigenvector approach [4][11][6]. On the other hand, the quadratic objective function has an advantage in that it tends to place components more sparsely than the linear objective function, resulting in a continuous solution closer to a physically feasible discrete solution. In this paper, we propose an /spl alpha/-order objective function to capture the strengths of both the linear and quadratic objective functions. We demonstrate that our approach yields improved spectral placements. We also present a bottom-up clustering algorithm which iteratively collapses pairs of nodes in a graph using local and global connectivity information, where the global connectivity information is derived from the clustering property of the eigenvector approach. The effect of our new spectral linear placement and clustering approach is demonstrated on benchmark circuits from MCNC.


In this paper, probabilistic approach has been made in the study of Makki, Madani and Mixed Suras of the Holy Quran. Using the word-size and word-length of Ayats, these Suras are categorized by word-length and a frequency distribution is obtained. The paper highlights the constructional characteristics of the two types of Suras in the Holy Quran. We have also discussed the dispersion and shapes of word-size and word-length of Makki and Madni Surras at other compositions of Surras as introduced by Quran Mufassirs and scientists.


Since the late twentieth century, waterfront development projects have become a topical urban form that is often hailed as a generator of economic growth and strategies to convert derelict docklands in thriving communities. This book situates waterfront developments all over the world in the respective context, that is composed, on the one hand, of 'fixeties' such as institutional structures or the built environment and, on the other hand, of 'flows' such as labour, capital, energy and knowledge. Case studies include developments in London, Dublin, New York, Seattle, the Caribbean, Buenos Aires, Toronto, Boston and Rotterdam.


We investigate whether changes to cross-functional or cross-organizational personal networks following a large corporate merger and acquisition improve junior executives' career outcomes. Previous research on networks and career success has focused on stable organizational environments, finding that large, open networks with many structural holes are most advantageous because of superior information benefits and control power, while closed networks provide redundant information that is unhelpful career-wise. However, we suggest that while dense, closed networks formed within organizational boundaries might be detrimental to executives' future promotability, closed networks are helpful if they are created across boundaries. These ties help to facilitate knowledge transfer and develop a new superordinate post-merger identity and are ultimately valued by the organization. We tested this on junior executives' email network data collected at two time points (pre-merger and a year later) from the newly-merged o...


Here we describe a rare clinical case of female with a history of surgical sterilization coupled to ectopic pregnancy in the fallopian tube stump, comprising on average 1.19 % of total ectopic pregnancies. The patient E. was admitted to the gynecological department complaining of aching pain in the lower left abdominal quadrant, blood discharge from the genital tract, and delayed menstruation. Due to a previous operation for sterilization, no onset of pregnancy was expected. A positive urinary test for human chorionic gonadotropin was obtained, whereas ultrasound examination did not reliably confirm the onset of pregnancy. However, taking into account the ultrasound signs of the hematoperitoneum, a culdocentesis was performed that revealed dark liquid non-clotting blood. Laparoscopic surgery was performed on emergency indications. Intraoperatively: the stump of the left fallopian tube was dilated, cyanotic, and blood was leaking from the fimbria lend. Bilateral excision of fallopian tube stumps was performed. The primary clinical diagnosis was interrupted left-sided tubal pregnancy (in the fallopian tube stump) that was confirmed by pathomorphological examination. Thus, the clinical case described by us demonstrates properly conducted differential diagnostics as well as timely management and therapeutic interventions. Hence, previous surgical sterilization recorded in patient history should not rule out a diagnosis of ectopic pregnancy.


Introduction and objectives:  Cervical cancer is the only gynaecological cancer that is staged clinically. The clinical stage of cervical cancer relies largely on the pelvic examination. The aim of this study is to analyse the discrepancy between clinical stage and pathological results, and to explore the accuracy of pelvic examination.


10% of platelets become activated . In our opinion, and in keeping with the percentage of platelets adhering to collagen reported in our paper [2], this response can be attributed to adhesion, a phenomenon that is not affected in Gaq/Ga13double deficient platelets [9], rather than to aggregation. The independence of these adhering platelets from ADP release was further demonstrated by treatment with the P2Y12 receptor antagonist ARC69931MX [9], which was also used in our platelet preparation [2]. Establishing whether this observed small percentage of platelets adhere to collagen as the result of direct activation through GPVI was not and is not the aim of our study. Moreover, it has been demonstrated that collagen is capable of eliciting PLCc2 phosphorylation, responsible for Inositol-1,4,5-triphosphate which, in turn, causes Ca release, without the concomitant participation of ADP and TxA2 (5,7 among the others). Finally, we agree that the P2Y1 receptor might, in combination with aspirin, be a promising target for future pharmacological approaches, as we believe that reducing platelet aggregation is far more important than reducing platelet shape change in the prevention of thrombus formation. However, we disagree with the statement it would appear more advantageous to improve pharmacological targeting of secondary agonist pathways rather than collagen receptors themselves , as at present there is not enough experimental evidence in this regard. We therefore consider this final assertion of Ohlmann et al. [1] to be highly speculative and wish to state categorically that neither challenging the role of ADP receptor antagonists nor suggesting the utility of collagen receptor inhibitors was the hidden intentions of our study reported in the Journal of Biological Chemistry.


This essay argues that much of the writing about journalism in China has suffered from an approach that is increasingly unhelpful in understanding both the ways in which the mass media operate on a daily basis and their relationships "upwards" to the party and "downwards" to the population who form their audience. In this, it lags behind the broader work on the media, particularly on television and film, which has had a much more inclusive perspective (Curtin, 2007; Keane, 2007; Keane, Fung, & Moran, 2007). In general, however, the study of the media in China, even in its broader forms, has always been heavily concerned with the influence of politics. There are good reasons for this: state, economy and society in China are much less clearly distinguished than is the norm inWestern capitalist societies, and in particular than in the USA, from which so much writing about this subject tends to emerge. The Chinese media are still, as they have always been, very much concerned with propaganda, and each media organisation was and is responsible to the appropriate party committee (Brady, 2008). While this relatively narrow focus might thus be justified, there is clearly more to be said about the Chinese news media than this dominant approach is prepared to recognise. In part, this is a symptom of a much more general problem in the study of the news media, and in particular in the practice of its comparative dimension. Both the venerable Four Theories of the Press (Siebert, Peterson, & Schramm, 1956) and its current successor volume Comparing Media Systems (Hallin & Mancini, 2004), are resolutely focused on the relations between the media and politics. While this must certainly be an important focus for any comparative study, it is completely unconvincing as an account of the whole of the mass media. At best, it applies to a small proportion of TV and radio output: at a generous estimate news and current affairs cannot amount to much more than 10% of the total broadcasting hours in most countries, even China. It applies to some sections of newspapers, but today even the most venerable journals of record have section after section devoted to issues other than Congressional debates and Wall Street stock prices. It applies to only a tiny number of magazines, out of literally thousands in all of the larger societies. It applies to some of the things said and written in the new media, but everywhere,


Introduction:
 Atrial fibrillation (AF) is the most common sustained supraventricular arrhythmia worldwide. Most conditions linked to AF, such as cardiovascular (CVD) and valvular disease, are linked to elevated atrial pressures and atrial cardiomyocyte (CM) stretch, which are powerful stimuli for atrial remodeling. We have shown that the proinflammatory and mechanosensitive cytokine tumor necrosis factor (TNF) is a key mediator of stretch-related atrial remodeling and AF.

 Hypothesis:
 As TNF is a critical factor mediating fibrosis, hypertrophy, inflammation, and arrhythmias in CVD, we hypothesized that targeting TNF-dependent signaling may offer a novel therapeutic target in AF patients.

 Methods:
 We created an aortic regurgitation (AR) mouse model of volume overload characterized by elevated left ventricular end diastolic (LVEDPs) and atrial pressures. To examine TNF-dependent AF pathogenesis in AR, the impact of
 Tnf
 excision in atrial CMs (Cre-recombinase expression controlled by an
 Nppa
 promoter) and pharmacological TNF inhibition with Etanercept (twice-weekly, 2.5 mg/kg) beginning 2-days (early) or 1-week (delayed) post-AR in CD1 mice were examined. Cardiac structural, functional, and electrophysiological properties were assessed using echo, pressure telemetry, immunohistochemistry,
 in vivo
 intracardiacs, and
 ex vivo
 optical mapping of AF.

 Results:
 Four weeks of AR resulted in chronically elevated LVEDPs and progressive LV dilatation, functional impairment, and hypertrophy in the absence of ventricular arrhythmias with or without TNF inhibition compared to SHAM mice. In atria, AR resulted in both
 in vivo
 (8/11, 73%) and
 ex vivo
 (5/8, 63%) AF inducibility, which was associated with hypertrophy, fibrosis, and macrophage infiltration (F4/80
 +
 ) as well as decreased conduction velocity and atrial effective refractory periods. Importantly, atrial CM-specific
 Tnf
 excision (n=10) and both early (n=8) and delayed (n=6) pharmacological TNF inhibition attenuated AR-induced adverse atrial remodeling and protected against AF inducibility.

 Conclusions:
 AF pathogenesis and vulnerability with AR requires TNF, suggesting TNF is an important therapeutic target for the prevention and treatment of AF linked to elevated atrial pressures.


We first research the development of simulation system based on HLA, then take the tanks warfare scenario as an example to illustrate the development and the realization of the weapon countermine simulation system based on HLA, and propose a strategy for system safety.


The present study delt with the effects of di-(2-ethylhexyl)-phthalate (DEHP) on the skeletal system of the prenatal fetuses of 20thday of gestation. DEHP treatment caused fetal mortality, retarded weight, length and ossification of some bones and shortness of others. Skull, vertebrae, sternum, girdles and limbs were the main affected by DEHP.


Fault diagnosis of power systems is an important task in power system operation. In this paper, fuzzy reasoning spiking neural P systems (FRSN P systems) are implemented for fault diagnosis of power systems for the first time. As a graphical modeling tool, FRSN P systems are able to represent fuzzy knowledge and perform fuzzy reasoning well. When the cause-effect relationship between candidate faulted section and protective devices is represented by the FRSN P systems, the diagnostic conclusion can be drawn by means of a simple parallel matrix based reasoning algorithm. Three different power systems are used to demonstrate the feasibility and effectiveness of the proposed fault diagnosis approach. The simulations show that the developed FRSN P systems based diagnostic model has notable characteristics of easiness in implementation, rapidity in parallel reasoning, and capability in handling uncertainties. In addition, it is independent of the scale of power system and can be used as a reliable tool for fault diagnosis of power systems.