Significance Designing efficient enzymes could contribute to a sustainable future. Current computational approaches, including physics-based and machine learning–based design, have not led to a robust enzyme design. Predicting enzyme catalytic power is the crucial step for enzyme design. Here, we found that the properties of enzymes are correlated in a nontrivial way with their evolutionary information. For the active site region and the more distant region, the statistical energy obtained from the maximum entropy model for enzyme homologs is strongly correlated with enzyme catalytic power and stability, respectively. The findings here could be used to understand enzyme catalysis and evolution. Combining the present approach with physics-based computer modeling can provide a potent tool for enzyme design. Although computational enzyme design is of great importance, the advances utilizing physics-based approaches have been slow, and further progress is urgently needed. One promising direction is using machine learning, but such strategies have not been established as effective tools for predicting the catalytic power of enzymes. Here, we show that the statistical energy inferred from homologous sequences with the maximum entropy (MaxEnt) principle significantly correlates with enzyme catalysis and stability at the active site region and the more distant region, respectively. This finding decodes enzyme architecture and offers a connection between enzyme evolution and the physical chemistry of enzyme catalysis, and it deepens our understanding of the stability–activity trade-off hypothesis for enzymes. Overall, the strong correlations found here provide a powerful way of guiding enzyme design.


Using a new method of plasma spraying,ZrO2 thermal barrier coating was formed in the course of plasma spraying.The energy of ultrasonic kept invariable,the influence of frequency changing on the adhesive strength of the coating was studied and compared with the condition without ultrasonic.The result shows that the proper arc-ultrasonic frequency can improve the adhesive strength of the coating and the stability of the plasma spraying process.


In this essay, I will offer some thoughts on how we might reframe the issues governing the admissibility of expert evidence. My principal focus is not on any particular type of expert evidence but on broader questions: the extent to which we ought to rely on rulings of admissibility, the standards that should govern admissibility rulings, and the role of the trial and appellate courts in making those rulings. To some extent, I will concentrate on the context of criminal cases, but for the most part my conclusions apply in both civil and criminal litigation. Here are my conclusions: First, the standards for treatment of expert evidence should differ depending on the litigation context. Standards should be very lenient for criminal defendants, and tougher for prosecutors, with the standards for civil litigants somewhere in between. Second, more than has been the case, the test that carries the bite with respect to expert evidence should be one of sufficiency rather than of admissibility. Third, the model created by Daubert v. Merrell Dow Pharmaceuticals, Inc. and General Electric Company v. Joiner, and extended by Kumho Tire Company, Ltd. v. Carmichael, in which trial courts, reviewed under an abuse of discretion standard, act as gatekeeepers to prevent jurors from being bamboozled by unreliable evidence, is not a useful one. Reliability is an inappropriate, misleading standard for testing the admissibility of expert evidence. It does not reflect the way we should think about admissibility issues,


The geometry of moving oceanic lithospheric plates is modeled easily by combining plate subduction and destruction with an application of Euler's theorem to the Euclidean sphere of the earth's surface. However, continental masses must respond to drift motion in a different manner because they cannot sink into the denser mantle. A theoretical geometric analysis, tested by data from the eastern Pacific margin, is presented to illustrate the unique response to drift of large continental masses. If they are large enough to comprise a significant fraction of the earth's circumference, an alignment of continental masses should undergo extension until the frontier between them and the ocean over which they encroach approximates a global great circle. This extension should entail secondary sea-floor spreading transverse to primary spreading directions, localized where continental masses along the frontier are narrow and therefore weakest, and ductile stretching and fracturing of the narrow continental spans. Continued sea-floor spreading and continental drift beyond the stage at which the continent-ocean frontier approximates great circle configuration presents a new problem. The maximized frontier length must now adjust to a decreased area of encroached ocean. Adjacent continents must now approach each other along the frontier direction, and formerly stretched and disrupted continental spans must be 'bent' to account for the excess frontier length. Recent reconstructions of post-Paleozoic continental drift indicate that the American and Antarctic continents and intervennig Caribbean and Scotia seas and island arcs may have undergone such a history.


In order to understand the energy consumption condition and the influencing factor of Huainan residential building, the present situation of this city energy consumption has been understood through questionnaire survey, as well as the major effective factor of this city year energy consumption has been find through the relevance analysis and the multiple regression analysis in this article. Meanwhile the multi-dimensional statistics linear regression mode of Huainan residential building year energy consumption has been constructed through above statistical method, the results indicated that the family yearly income and the construction type is biggest influencing factor to the residential building year energy consumption.


The psychosocial, emotional and technological adaptation needs of the elderly have been increasing for several reasons. The objective of this study is to carry out a review about the main results of the research on these issues, with the long term goal of designing, implementing and perform a differential evaluation of a comprehensive program for the development of these competences in older people through the tools of Web 2.0. The study was divided into two parts. In the first, we present evidence from the review process on emotional and psychosocial variables. The second shows the results obtained in relation to the tools of Web 2.0. Finally, we discuss the relevance of developing interventions in this line. During this research study, we received competitive funds from the Spanish Ministry of Education, Science and Innovation (MICINN) (EDU2010-19250 / EDUC) for 2010-2013, awarded to the Director/Main Researcher (J. N. Garcia). C. Diaz-Prieto received funds from the FPU MECD for 2013-2017.


The low voltage ride-through (LVRT) capability of wind farms has a great impact on the power system stability. A novel technology is proposed to improve the low voltage ride-through capability of wind farms using series dynamic braking resistor (SDBR) which can boost terminal voltage and dissipate active power. A switching scheme of SDBR is introduced based on the dynamic stability margin of speed-voltage. This paper uses a representative wind farm model based on fixed speed wind turbines to study the transient LVRT stability. Both detailed analysis and simulation results show that SDBR can significantly improve the low voltage ride-through performance of wind farms, and the switching scheme of SDBR is simple and effective. The technology can reduce wind farm's dependence on the pitch control systems and alternatives in riding through low voltage fault, and allow retrofit existing wind farms.


Chang, H. W. J.1*, Francis, A.S2, J. Dayou2, J. Sentian3 & Chee, F. P.2 1Preparatory Center for Science and Technology, University Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia 2Energy, Vibration and Sounds Research Group (e-VIBS), Faculty of Science and Natural Resources, University Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia 3Climate Change Research Group (CCRG), Faculty of Science and Natural Resources, University Malaysia Sabah, Jalan UMS, 88400 Kota Kinabalu, Sabah, Malaysia. *[E.Mail: firstname.lastname@example.com ]


Simple tables requiring at most a linear interpolation and addition are presented for the speed of sound in the open ocean. These tables cover the range 30–42 0/00 S, −2°–32° C, and 0–1100 kg/cm2 gauge, so they have some applicability also to the Mediterranean and Red Sea. The tables were produced from an equation having a standard deviation of 0.05 m/sec which fit at NUC to the latest NRL measurements.


The invention provides a preparation method of a polypropylene cable material and the polypropylene cable material.The preparation method comprises the step that 1-5 parts of a grafting agent, 0.2-3 parts of a grafting auxiliary agent, 0.05-0.20 part of an initiating agent and 2-10 parts of a grafting agent carrier are mixed to be uniform and then subjected to co-extrusion with 100 parts of polypropylene resin added with 0.2-1.5 parts of a stabilizer and 2-5 parts of a catalyst.The polypropylene cable material obtained through the preparation method is resistant to high temperature and high pressure and high in tensile strength, the tensile strength can reach up to 35 MPa, the elongation at break is not lower than 300%, the tensile strength changing rate is not larger than +/-10% after aging is performed under the temperature of 135 DEG C for 168 h, a cable manufactured by adopting the polypropylene cable material can be used under the environment of high temperature, high pressure and even existence of H2S and is small in damage rate and long in replacement period, and the replacement period of a petroleum cable is effectively prolonged.


Objective To understand the knowledge and perception of community public health practitioners on immunization for patients with diabetes mellitus, and to make recommendations for the improvement of community diabetes care. Methods From each of the community immunization clinic in an urban area of Guanghzou, a public health practitioner was interviewed in depth. Descriptive statistics were used to describe the basic features of the data, and Chisquare test was used to compare proportions between different groups. Results Thirty-seven public health practitioners were interviewed. Twenty-four(64.9%) mentioned that influenza-associated pneumonia is particularly common for patients with chronic conditions. Twenty-three(62.2%) believed that mortality from influenza is high in patients with chronic conditions. Fifteen(40.5%) mentioned that patients with chronic conditions are at higher risk for pneumococcal disease.Only nine interviewees(24.3%) believed that patients with chronic conditions should be vaccinated against influenza. Most interviewees knew little about the efficacy and effectiveness of the 23-valent pneumococcal polysaccharide vaccine.Barriers to reaching higher rates of influenza and pneumococcal polysaccharide vaccination in diabetic patients include poor public awareness, no target vaccination coverage, and worries about adverse events following immunization.Conclusion The community public health practitioners were aware of influenza and pneumococcal disease. We should take measure to improve influenza and 23-valent pneumococcal polysaccharide vaccination in patients with diabetes mellitus include health education and training, greater resource inputs, and service improvement.


Modifying the set value is based on the waiting time until then is changed to a value other than 0 (zero) is the output of the open signal of the flow control valve is started, the difference between the target value and the measured value of the management response time of the flow It executes a control operation for repeatedly. As a result, the response time after setting of the flow rate is changed until the flow rate reaches a set value, the fluid type, set flow rate, regardless of the temperature, individual difference in pressure and the device, it is possible to the desired value . Is also multiplied by a weighting factor to the difference between the target value and the measured value of the management response time, it may be in response to each of a plurality of predetermined range of flow rates so as to execute the control operations.


Gibellula pulchra (Sacc.) Cavara and Gibellula leiopus (Vuill.) Mains are the only two species of Gibellula reported to be pathogenic on spiders in North America (Mains, 1950). The geographical distribution data for these fungi on this continent suggest that they occur mostly in the eastern United States (Mains, 1950). Records show the northern limit for G. pulchra is Maine (Mains, 1950), and for G. leiopus there are two reports on spiders from Canada: one was collected at Brookside, Nova Scotia (Mains, 1950), and the second was a 1979 collection (DAOM 189850) by N. Binyamini from Gatineau Park, Quebec deposited in the herbarium of the Biosystematics Research Centre, Ottawa, Ontario (BRC).


Haemostatic abnormalities may occur in 1–2% of patients treated with l‐asparaginase. Here, we present the second case of a myocardial infarction, developing in a patient with acute lymphoblastic leukemia (ALL), in the course of l‐asparaginase treatment. In our patient and in the only one reported case from the literature, a recent exposure to vincristine and daunorubicin was also reported, but induction chemotherapy program was completed as scheduled, with the only withdrawal of l‐asparaginase. Myocardial infarction should be included in the list of thrombotic complications possibly associated with l‐asparaginase treatment, or with a combination of l‐asparaginase and vinca alkaloids/anthracycline.


Diabetic ulcers are the most unloved and frightening chronic complications for patients, bacteria that are resistant to certain antibiotics giving considerable attention to health agencies around the world. This suggests that antibiotics do not work optimally and that the diseases that have initially improved, can be experienced back with a worse prognosis. Objective: To know the sensitivity of antibiotic to bacteria in pus patient of diabetes mellitus ulcers. Method: This study was conducted by taking a sample of pus from patients with ulcers of diabetes mellitus. The samples obtained were identified and isolated to obtain the type of bacteria present in the pus. After obtaining the type of bacteria contained in the pus carried out the sensitivity test by using the method of diffusion caktram and diamtai diameter zone inhibition of bacterial growth formed Result: The type of bacteria from the sample obtained by bacteria Staphylococcus and Pseudomonas Aeruginosa. Antibiotics that show sensitivity to bacteria result from diabetes mellitus ulcer pus isolation is gentamicine with result of measurement 24.3 mm and seftazidine with measurement 18.7 mm.


Acknowledgements Note on Names 1. 'The Lady at their Head': Women and the Landed Estates 2. 'The Business and Charities of the Parish': Churches, Schools, and Local Authority 3. 'Many to Take Care of': Charity, Philanthropy, and Paternalism 4. 'Aristocratical and Female Influence': Elections and Electioneering 5. 'Party' Politics: Metropolitan Political Society. 6. 'A Busy and Suspicious "Cabal" or "Head Housemaids"'? The Ladies of Queen Victoria's Household Conclusion Biographical Appendix Bibliography


Mono-ligand complexes of the tridentate ligand N-(2-methylthiophenyl)- 2?-methylthiophenylmethyleneimine (SNS) of the type MX2(SNS) (M = Co, Ni, Cu; X = Cl, Br, I, or FCS) have been prepared. The electronic spectra indicate that the cobalt halide complexes are five-coordinate, whereas the complex Co(NCS)2- (SNS) and the nickel complexes are six- coordinate and polymeric. The copper complexes CuX2(SNS) (X = Cl, Br) are possibly five-coordinate. The bis-complexes of nickel [Ni(SNS)2]X2 (X = ClO4, BF4) are high- spin but the complex [Co(SNS)2](ClO4)2 appears to be a rare example of a low-spin octahedral complex of cobalt(II).


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The evidence developed in two years of study—with three lots of lambs on a ranch in Mendocino County—indicates that there are a number of factors involved in the "break" which frequently interrupts the finishing of lambs on irrigated ladino and grass pastures.


Enhanced field emission (EFE) presents the main impediment to higher acceleration gradients in superconducting rf (SRF) niobium (Nb) cavities for particle accelerators. A scanning field emission microscope was built at Jefferson Lab with the main objective of systematically investigating the sources of EFE from Nb surfaces. Various surface preparation techniques and procedures, including chemical etching, electropolishing, ultrasonic water rinse, high pressure water rinse, air-dry after methanol rinse, air-dry after water rinse in Class 10 cleanroom, were investigated. The capability and process variables for broad-area Nb surfaces to consistently reach field emission free or near field emission free performance at /spl sim/140 MV/m have been experimentally demonstrated using the above techniques/procedures.


An experimental study was performed to determine the environmental durability of the adhesive bond between fiber-reinforced plastic (FRP) and concrete. The study specifically focused on freeze-thaw cycling exposure of such bonds and their ultimate strength prior and after the environmental exposure. To investigate the bond strength 84 single lap shear specimens were manufactured utilizing two different types of carbon FRP pultrued strips and three different structural adhesives for total of three FRP/adhesive combinations. Two types of concrete substrate were used: regular high strength and air-entrained concrete. The specimens were freeze-thaw cycled for three different numbers of cycles using two different freeze-thaw procedures. First freeze-thaw procedure used chloride solution (3% NaCl) as its medium; the second procedure utilized tap water. This main program was complemented by the same freeze-thaw cycling of pull-off specimens of the adhesively bonded system and dumbbell tension specimens of the three adhesives. Coefficients of thermal expansion of the three structural adhesives were also experimentally measured. Results show that the ultimate strength of the adhesive bond between FRP and concrete deteriorates measurably during freeze-thaw cycling in chloride solution. This must be put into perspective as the concrete itself severely deteriorates during this type of freezethaw cycling. Therefore, the durability of the adhesive bond between FRP and concrete is dependent on the durability of the concrete. This is also supported by the results of testing of the adhesive tensile specimens that did not show decrease in strength only an increase in ultimate strain. The freeze-thaw cycling in water did not result in any deterioration of the specimens' strength, most specimens actually acquired higher strength, due to moist curing of the concrete during the freeze-thaw cycling. Thesis Supervisor: Eduardo Kausel Title: Professor of Civil and Environmental Engineering * )'/,j ~ ~i 2* , ~ <4~7Y <6 7/in ,4,'r t


Movies are an important part of our daily entertainment, with the global movie industry experiencing significant growth and capturing the attention of people of all ages. However, only a few movies achieve success, leading to pressure on movie production stakeholders. Therefore, researchers and moviemakers require expert systems that can accurately predict the probability of a movie's success prior to its production. Most research on predicting movie popularity has focused on post-production stages, but it's essential to predict a movie's success at an early stage to enable necessary changes to be made. To this end, a content-based movie recommendation system (RS) has been proposed that uses preliminary movie features such as genre, cast, director, keywords, and movie description. This RS output and movie rating and voting information are then used to create a new feature set, which is input into a CNN deep learning (DL) model to build a multiclass movie popularity prediction system. The study also proposes a system to predict the popularity of the upcoming movie among different age groups, dividing the audience into four categories: junior, teenage, mid-age, and senior. The study uses publicly available data from the Internet Movie Database (IMDb) and The Movie Database (TMDb). The multiclass classification model implemented in this study achieved 96.8% accuracy, outperforming all benchmark models. Overall, this study highlights the potential of predictive and prescriptive data analytics in information systems to support industry decision- making.


ABSTRACT Recent urbanization led to a more evident distinction in historical inner cities, consolidated urban periphery and peri-urban areas. The resulting metropolitan structures are moulded by social, economic, cultural and political factors, fuelling unregulated – and often dispersed – urban expansion. In this context, spatial planning was increasingly asked to regulate complex processes of metropolitan development. Under the hypothesis that discontinuous urban expansion was associated with planning deregulation or poorly effective zoning procedures, the present study introduces an operational approach aimed at comparing actual and planned land-use at the metropolitan scale in the Large Urban Zone (LUZ) of Rome, Italy. Settlements developed on land with less stringent building constraints have resulted in the discontinuous urban expansion. Because of increased house demand and high pressure for services and infrastructures, discontinuous urbanization in Rome has frequently involved out-of-plan land – with partial regulatory constraints or with mixed/ambiguous land destination – in areas with growing population. Going beyond a descriptive analysis of urban morphologies, empirical exercises comparing actual and planned land-use provide basic information to design developmental policies containing discontinuous urbanization.


What can be learned from Earth's past to guide our understanding of life in a warming world? Climate models are invaluable tools for understanding Earth's climate system. But examination of the real world also provides insights into the role of greenhouse gases (carbon dioxide) in determining Earth's climate. Not only can much be learned by looking at the observational evidence from Earth's past, but such know ledge can provide context for future climate change.


Abstract Isolation of volatile concentrate from the wood of Guaiacum bulnesia (Bulnesia sarmienti Lorenz ex Griseb., fam. Zygophillaceae), has been obtained by Supercritical Extraction with carbon dioxide. To obtain a pure volatile extract devoid of cuticular waxes, the Extraction products were fractionated in two separators operating in series. A good Extraction process was obtained operating at 120 bar and 800C in the Extraction vessel, at 120 bar and at –50C in the first separator and at a pressure between 20 and 15 bar and temperature in the range (10 – 200C ) in the second one. The composition of the volatile concentrate has been analyzed by GC-MS, the major component were α-guaiene, cis-β-guaiene and α-bulnesene. A comparison with the oils obtained by hydrodistillation is also given. GC-MS Analysis on the extracts revealed differences between the volatile oil obtained from Supercritical Extraction and the one extracted by hydrodistillation. In the case of Supercritical Extraction the yield was of volatile oil was 0.7 % by weight of the charged material.


Impact experiments are presented in this work. In order to analyse the behaviour of concrete under high strain rates, an impact mass is dropped from the maximum height of 9 m onto square concrete slabs with a side length of 1 m. Slabs of different concrete strengths are tested, thus the behaviour of standard concrete slabs is compared to the one of high performance concrete (HPC) and ultra high performance concrete (UHPC). Furthermore, the influence of subsequent fabric reinforcement is analysed. Different measurement techniques are used during the test procedure to study the relation of local damage and global structure behaviour. For instance, photogrammetry is used for monitoring the vertical displacement during the deflection of the concrete specimen. Beside measurement technique, stamping cone and damage effects due to the impact load are evaluated. Comparing the concrete specimen with or without additional fabric reinforcement, enormous differences in resistance to impact load and in penetration of the impactor are seen.


não! Abstract Selection, yes; collections, no ! The choice of bibliographic and audio-visual material is the specific function of the librarian, whose mission was defined by the essayst Ortega y Gasset as a filter placed between the flood of books and man. Collect ons of masterpieces of universal culture — as well as collections of national cultures - — should be avoided by public libraries as they end up being much more expensive than the purchase of the individual works in better and less expensive


The episode of Katanga's secession from the newly created state of Congo in 1960 offers an example of the difficulties by which the European powers ended an era in their colonial history. It proves how the process of decolonization was performed in an atmosphere of mutual distrust between Belgium and its former African territory. When revolts in the aftermath of Congo's independence began, Belgium and its advisors tried to limit the damage. Among these advisors, the National Bank of Belgium (NBB) was not the least. We will follow its attempts to work out a whole scale of measures to ensure the continuation of Belgian commercial and financial interests as well as what it thought to be the best interest of Katanga and Congo in general. The wish to preserve trade with the former colony was combined with an interest in helping the Congolese. However, the former colonizer, its business circles included, tried to take advantage of the problems of the young state in order to improve its position. The Katangese president Moise Tshombe and his people, so the Belgian leaders thought, would be easier to deal with. The 'Katanga-episode' in the decolonization period of Congo also makes clear that there were other players involved: Great Britain, who was still in power in nearby Northern and Southern Rhodesia; the United States of America; the United Nations; and numerous foreign 'adventurers' who tried to make an easy profit in the heart of Africa. The US, especially, was decisive in the outcome of this crisis.I. The Katanga SecessionBy the end of the 19505 it became clear that the colonial regime would not last much longer. In 1957 and 1958, there already had been agitation in the Belgian Congo that resulted in the beginning of political participation of the African population. In 1959, riots broke out and black political parties clamored for Congolese independence. At first the Belgian government proposed only to give more autonomy, but at the political roundtable conference in JanuaryFebruary 1960 the Belgian and Congolese participants agreed on full independence starting on 30 June of that same year. However, the hidden agenda of the Belgians was to maintain economic and financial influence in the new state. They would do this with agreements that it hoped to conclude at the Belgian-Congolese roundtable conference of April-May 1960, which was focused on economic, financial, and social matters. For example, the National Bank of Belgium, which did most of the Belgian preparations for this conference,2 launched the idea of having the two states manage the colonial portfolio on a basis of parity. This second roundtable conference did not go as smoothly as the first, and distrust among the Congolese negotiators prevented them from agreeing on anything other than general intentions. The tough questions concerning the future of the former colonial enterprises and assets would continue to generate disagreement.The case of the Union Miniere du Haut-Katanga (UMHK) is the most important example, and it will be a focus of this article. It was founded in 1906 by the Comite Special du Katanga (CSK), the Belgian holding company Societe Generale, and the British Tanganyika Concessions Ltd. The colonial government and private capital owned the CSK, dating from 1900. The UMHK held the concessions for the mining and mineral exploitation of the 'copper province." That would have made an independent Congo, as inheritor of the colony, the largest shareholder of the mining company. But before this date the Belgian government paid back to the private investors in the CSK one third of the capital. This became a big issue in Belgian-Congolese relations that wasn't resolved until 1967. On 23 June 1960, the UMHK itself became a Belgian company. Nevertheless, it remained of huge financial importance for the young state.3 In 1958 it produced 16.4 % of the colonial budget, and in 1964 it produced 33.7 % of the Congolese state income.4Shortly before 30 June 1960, the date on which the Belgian Congo was to become an independent state, there had already been marginal attempts by people of the Katangese Conakat Party to move for Katanga's secession. …


This paper describes the dynamic characteristic analysis of a high-torque spindle system for a heavy duty lathe. In the study, we performanced the analysis of a high-torque spindle system for our heavy duty lathe by using ADROS, which is our own developed S/W for dynamic analysis of spindle system. We get a results some analysis dynamic characteristics of a spindle, such as natural frequency, whirl frequency and critical speed.


Pulse width modulation (PWM) is extended to cases in which multiple signals are to be encoded into 2 single data stream, while still supporting. all the requirements of power conversion. This permits lossless recovery of multiple signals with a single set of converters. The approach has applications in digital PWM amplification of audio signals and in three-phase converters. It permits a unified AC link converter, for example, to conveniently deliver multiple output signals.


Traditionally, attention has been focused on uncertainty in customer demand. However, uncertainty is also inherent in the market on the supply side, because the quantity and quality of raw materials delivered from external suppliers may differ from those requested. This paper quantifies the financial impact of having uncertainty in a retail supply chain. Having unstable inventory records leads to profit losses in a supply chain. These inventory records may not be correct due to various causes such as transaction errors, misplacement, etc. These inaccuracies are caused by uncertainties in customer demand, parts supply and variations in the process itself. The aim of this paper is to examine the relationship between inventory inaccuracy and financial performance. The results indicate that each type of uncertainty can have different impacts on the chain and the elimination of uncertainty can more or less reduce supply chain costs and hence, increase profit.


This Thesis is submitted in partial fulfillment of the requirement for the degree of Masters of Arts in Literature at the University of Nairobi


The conditions of the urban environment in the aspect of progressive climate change mean that city spatial planning is becoming an increasingly greater challenge. The specificity of Krakow's centre stems from its historical urban grid and the placement of an exceptionally large fragment of the city under heritage conservation. This paper is the result of analyses in terms of urban environmental conditions in the Old Town area, and the objective of the study was to determine possible solutions to improve the living conditions of residents and enhance biodiversity. The measures are based on the idea of a human-friendly city that also limits the negative consequences of urbanisation.


The study was conducted on 10 multiparous Murrah bufialoes from day 20 pre-partum to day 30 postpartum at the cattle farm of the institute. Body condition score, milking temperament score, milk letdown time, milking time, milk yield and milking rate for morning and evening on days 1, 2, 3, 4, 5 and thereafter on 10, 15, 20, 25 and 30 days postpartum were recorded. Expert milker performed hand milking during the study period. Milk letdown time, milk yield, milking time and milking temperament scores varied significantly (P<0.01) on different days of study and no variation was observed between morning and evening milking. Body condition score reduced the slightly restless temperament (P<0.01) of buffaloes, but there was no effect on milking rate. Reduction in milking temperament Score significantly (P<0.05) increased both milk-letdown time and milk yield and there was no effect on milking time and milking rate. Body condition score during milking also significantly (P<0.0 1) improved milk yield at first month of lactation.


During the 40-years long development of Nafta-gas Co., the inventive activity of its workers was always included. Growing out of the afterwar enthusiasm with many pioneer-creators, it became carrier of the Company development. With the usage of new technologies and procedures, the produced reserves of hydrocarbons increased greatly, in spite of significant consumption growth. Besides drastic decrease of oil prices, however paradoxical it may seem, the considerable development of explorative techniques became evident, and the modern technologies applied in Nafta-Gas Co. in well planning contributed to significant decrease of explorative expenses


The present invention relates to preparations based on vegetal extracts of Ajuga reptans for favouring the growth of hair and stimulating the hair bulb. The preparations of the invention are in suitable formulations for oral administration or local application and are specifically suitable for the prevention and treatment of androgenic alopecia in males and females.


duty of reliance on faith and prayer; the indisputable results of the revival of trust in spiritual agency; the aberrations of "Christian Science"; the necessity of the testing by scientific experts of all evidence of spiritual healing; the duty of consecrating personal gifts to God; thankfulness for the triumphs of medical and surgical skill; improvements recommended in Pastoral Visitation, especially the addition -of collects more hopeful of recovery; the permission that such prayers should be accompanied by the Laying-on of Hands; the difference between Psychic Forces and Spiritual; the need of prayer for guidance on the whole subject; the impossibility of giving official recognition at present to " Giftsof Healing "; caution to those who believe themselves to have such gifts, especially as to the need of medical study and the avoidance of Occultism and Spiritualism. With regaid to the practice of anointing with oil, the Bishops pointed out the obscurity as to the primitive practice; the gradual attraction of the practice as an encouragement to faith into a sacramental preparation for death; and though refusing to prohibit it, declared that at present it could not be authorized by the Church, but that the bishop of each diocese should be consulted. The Archdeacon went on to show how large a part the healing of the sick occupied in the ministry of Christ and His Apostles, and of the Church at large. To the continuance of these gifts evidence was given by Justin Martyr, Irenaeus, Origen, Ambrose, Chrysostom, and Augustine. To the practice of anointing the sick with oil with a view to recovery testimony was found in Tertullian, Serapion, Jerome, the Apostolical Constitutions, the Testamentum Domini, St. Martin of Tours, and others. From the great mass of works of healing in the Middle Ages down to the present time, Mr. Dearmer, who had written on the subject, had selected a list of forty-five, including in recent times George Fox, Jonn Wesley, Prince Hohenlohe, Father Matthew, Dorothea Trudel, Pastor Blumhardt, and Father John of Cronstadt. Hutton, the late editor of the Spectator, took a favourable view of these agencies. In England until the end of the reign of Queen Anne was retained the custom of touching by the king for scrofula, with indisputable results in certain cases. The part borne by faith in healing was fully recognized in the BRITISH MEDICAL JOURNAL. From the JOURNAL accounts were quoted of three remarkable faith healers Valentine Greatrakes, the Deacon de Paris, and Johann Joseph Gassner. The cures effected at Lourdes might be reckoned at about 5 per cent. In modern times an American movement for faith healing had begun in an episcopal church in Boston, which had not received much encouragement from the authorities on nervous diseases; its promoters had finally decided that nothing should be attempted without the sanction of a responsible physician. In this country, Dr. Alexander Robertson, Physician of Glasgow Royal Infirmary, had practised healing by mental suggestion as far back as 1871 and 1889. In London an association had been formed in 1908, called the Church and Medical Union for the promotion of the recognition of the power of faith in sickness in co-operation with medical skill. There was also the Society of Emmanuel, conducted by Mr. James Hickson, with a view to the employment of spiritual forces in healing. Articles were quoted from the BRITISH MEDICAL JOURNAL which supported the cautious views of the Bishops at Lambeth, acknowledging the wonderful power of mind over matter, and pointing out thelessons to bedrawn from thepast history of faith healing. ThA Archdeacon referred to a remarkable discussion at the Harveian Society at a meeting held last autumn, when the powers of suggestion in mental and nervous diseases was fully acknowledged, while the final responsibility of the experienced practitioner was strongly maintained. The upshot seemed to Archdeacon Sinclair to be that there were no limits to the powers of faith and prayer; that many persons, like wise parents, had a gift of personal impressiveness; that the subconscious self was a fact in psychology; that the clergy might do more in their visitations of the sick by encoouragements to faith;* that the laying.on of hands anld the anointing with oil .might be tangible helps to faith; and that religion and medical science should always co-operate, while the ultimate responsibility must lie with the accredited physician. HEALTH VALUES.


A semiconductor integrated circuit device and a technique related to a method of manufacturing a semiconductor integrated circuit device corresponds to a semiconductor substrate having an active island, embedding a predetermined portion of the active island gate, a source and a drain, the drain bottom is formed on the gate both sides comprising a current blocking layer formed on the active island regions, may be constructed from the drain through the lower part at the time of the current flowing, the source is discharged into the semiconductor substrate.


Cairncrossite is a new phyllosilicate species found in manganese ore on dumps of the Wessels Mine, Kalahari Manganese Field, South Africa. Associated minerals are richterite, sugilite, lizardite and fibrous pectolite. It occurs as radiating platy micaceous aggregates of up to 1 cm in size. Cairncrossite is colourless, appearing white, and the crystals are translucent to transparent with a white streak and vitreous to pearly lustre. The crystals are sectile before brittle fracture, with a Mohs hardness of 3. A perfect cleavage parallel (001) is observed. The calculated density is 2.486 g cm −3 . The mineral is biaxial positive with n α = 1.518(2), n β = 1.522(2), n γ = 1.546(2), 2 V obs = 33.9(6)° (2 V calc = 44.97°) at 589.3 nm and 24°C. The orientation of the indicatrix is Z ^ c * = 10°. The dispersion is weak ( r v ) and no pleochroism is observed. An intense light-blue fluorescence is emitted under shortwave UV radiation. Cairncrossite is triclinic, space group P 1 ¯ , a = 9.6265(5), b = 9.6391(5), c = 15.6534(10) A, α = 100.89(1), β = 91.27(1)°, γ = 119.73(1)°, V = 1227.08(13) A 3 , Z = 1. The strongest lines in the Gandolfi X-ray powder-diffraction pattern [ d in A( I )( hkl )] are 15.230 (100)(001), 8.290 (15)(1–10), 5.080(25)(003), 3.807(30)(004), and 3.045(20)(005). The chemical composition obtained by electron-microprobe analysis is Na 2 O 3.06, K 2 O 0.11, CaO 18.61, SiO 2 54.91, SrO 11.75, total 88.44 wt%. The relevant empirical formula, based on 16 Si atoms per formula unit ( apfu ) and TGA data is: Sr 1.99 K 0.02 Ca 5.81 Na 1.73 Si 16 O 55.84 H 30.33 . Taking variable sodium contents into account, the idealized structural formula is Sr 2 Ca 7–x Na 2x (Si 4 O 10 ) 4 (OH) 2 (H 2 O) 15–x with 0 ≤ x ≤ 1, and the simplified formula for sodium-rich crystals is SrCa 3 Na(Si 4 O 10 ) 2 (OH)(H 2 O) 7 with Z = 2. The structure of cairncrossite was refined on single-crystal X-ray data (Mo K a radiation) to R 1 = 0.047. Cairncrossite belongs to the gyrolite and reyerite mineral groups, it is characterized by sheets consisting of edge-sharing CaO 6 octahedra, which are corner-linked on both sides to silicate layers. These units are intercalated by layers formed by SrO 8 polyhedra, which are arranged in pairs via a common edge, and further bound to disordered NaO 6 polyhedra. A complex system of hydrogen bonds strengthens the linkage to adjacent silicate layers. Cairncrossite exhibits a two-phase endothermic weight loss of the H 2 O molecules in the range 25–400°C; however, the mineral shows a nearly complete rehydration capability up to 400°C. The new mineral is named in honour of Bruce Cairncross, Professor and Head of the Department of Geology, University of Johannesburg.


demonstrate an array of interesting behavioral and morphological traits ( 1, 2, 3 ), but many of the approximately 1,700 species have not been investigated in depth. I studied a population of Steniolia nigripes located at the Granite Mountains in the Mojave Desert, California, from 2008 to 2013. I present information on the distribution and habitat of these wasps, as well as seasonal patterns in population size and location. I also discuss the response of Steniolia nigripes to environmental variation. In addition, I describe the behavior of wasps of both sexes, including foraging, prey selection, aggression, and space use. This paper represents the first truly comprehensive description of S. nigripes natural history and behavior. The presence of photosynthetic microorganisms in desert rocks has come to be expected. E. I. Friedmann and has shown that at sites from around the world, including the Antarctic Dry Valleys, the Negev Desert in Israel and the Atacama Desert in Chile, wherever high aridity precludes the establishment of so-called epilithic organisms on the surfaces of stones and


Various aspects of multidimensional random fields are studied by means of space transformations. The latter are elegant and comprehensive Radon operations which can solve complex multidimensional problems by transforming them to a suitable unidimensional setting, where analysis is considerably simpler. It is shown that spatial correlation functions in R/sup n/ are uniquely determined by means of their space transformations in R/sup 1/. Necessary and sufficient conditions are established in order that a spatial random field (in R/sup n/) be represented as the linear combination of pairwise uncorrelated random processes (in R/sup 1/). Space transformations provide analytically tractable criteria for testing the permissibility of correlation functions and constitute an attractive instrument for spatial and spatiotemporal random field simulation and for studying stochastic partial differential equations. Several examples and a case study are discussed. >


The present invention relates to a transfer sheet characterized in that a fluororesin layer, wherein reflective particles such as pearl particles or glass particles for giving metal texture are dispersed, is formed on a carrier film and an adhesive layer is formed on said fluororesin layer, and an exterior laminate film characterized in that by transferring said transfer film on a synthetic resinfilm, the fluororesin layer containing reflective particles forms a surface layer, and an adhesive layer and a synthetic resin film are in turn laminated under said fluororesin layer. The exterior laminate sheet according to the present invention can easily give physical properties, such as excellent weather resistance, corrosion resistance and stain resistance, resulting from the fluororesin to windows/doors and panels, and it is so flexible that it has an effect of easily constructing curved surfaces. In addition, the exterior laminate sheet according to the present invention is allowed to use pearl particles or glass particles having large particle size by adopting formation of a fluororesin layer containing reflective particles as a coating method, whereby it has an effect that a decoration effect may be maximized.


Privacy protection is an important problem in workflow scheduling, for which scheduling tasks with privacy constraints to reliable resources is essential. In this article, we consider the scheduling problem of Spark applications in a hybrid cloud with deadline and privacy constraints. A scheduling algorithm framework is proposed, which consists of four algorithm components. Candidate strategies are developed for each algorithm component. The components and parameter values are statistically calibrated over a comprehensive set of random instances. The proposed algorithm is compared to modified classical algorithms for similar problems. The experimental results indicate that the proposed algorithm outperforms the compared algorithms under different application scales, deadlines, and private VMs


Summary x =: axial component r = radial component = condition at wall The axisymmetric subsonic and supersonic flow fields, and the skin friction and heat transfer of an electrically conducting com pressible fluid flowing in a channel of constant circular area through a magnetic field are investigated when the magnetic Remolds number is small. The inviscid-flow field for flow through a dipole field is solved by the method of characteristics in the supersonic case. For the subsonic case, linearized equa tions are derived for small values of the magnetic interaction parameter. Numerical results are obtained by the relaxation method. The inviscid-flow-field solutions are used as boundary condi tions for the laminar boundary layer along the wall, in which axial pressure gradients form an important feature. The exact continuum-flow equations are reduced by an order-of-magnitude analysis to the boundary-layer equations, which are solved nu merically by an integral method using a fourth-degree velocit}^ profile and a fifth-degree stagnation-enthalpy profile. Pressure, temperature, and heat-transfer measurements are made with a shock tube under supersonic-flow conditions closely approaching those used in the numerical computations. Gen eral agreement is found between the theoretical and the experi mental results.


Alzheimer's disease (AD) is a devastating neurodegenerative disease and the primary cause of dementia, with no cure available. The pathogenesis of AD is believed to be primarily driven by the accumulation of Aβ, a 4-kDa peptide generated from the amyloid-β precursor protein (APP) through proteolysis. APP is a type-I trans-membrane protein which is constitutively expressed in many tissues, including the eye. Emerging evidence support that visual impairment and several common eye disorders may share common pathogenic determinants with AD. Over the past decade, an increasing number of researches have been utilizing mouse models to investigate the underlying mechanisms of human disorders. Intriguingly, AD animal models present devastating amyloidopathy not only in the brain but also in the eye. This article aims to describe the progress in understanding the pathophysiology and pathogenesis of AD, focusing on the amyloidopathy in visual impairment. Moreover, the studies described in this review support the potential use of non-invasive ocular tests for screening AD patients at an earlier stage and for assessing treatment efficacy of AD.


This article examines the paradoxes inherent in filmic time, with particular reference to the autobiographical work of the British director Terence Davies. Analysing ways in which film, itself constructed from still images, can create, reverse or freeze temporal flux, confuse and blend multiple and conflicting temporalities, and create the spatian dimensions of an 'imaginary' time, it argues atht the relationship between film and music may well provide a fundamental key to the understanding of filmic time.


People with severe mental illness served by public mental health systems have rates of co-occurring chronic medical illnesses that of two to three times higher than the general population, with a corresponding life expectancy of 25 years less.1,2 Treatment of these chronic medical conditions in those with serious mental illness is often substandard, with many receiving no treatment at all. Much of the treatment they do receive comes from costly ER visits and inpatient stays, rather than routine screenings and preventive medicine.2,3 In 2003, in Missouri, for example, more than 19,000 participants in Missouri Medicaid had a diagnosis of schizophrenia. The top 2,000 of these had a combined cost of $100 million in Missouri Medicaid claims, with about 80% of these costs being related not to pharmacy, but to numerous urgent care, emergency room, and inpatient episodes. The $100 million spent on these 2,000 patients represented 2.4% of all Missouri Medicaid expenditures for the state's 1 million eligible recipients in 2003. In general medical benefi t programs, these chronic medical conditions, including congestive heart failure, hypertension, diabetes, and asthma are frequently targeted for disease management interventions. Joseph J. Parks, MD, is Chief Clinical Offi cer, Missouri Department of Mental Health. Tim Swinfard, MS, is President/CEO, Missouri Coalition of Community Mental Health Centers, Jefferson City, MO. Paul Stuve, PhD, is Project Manager, Care Management Technologies, Jefferson City. Address correspondence to: Joseph J. Parks, MD, Missouri Department of Mental Health, 1706 E. Elm, PO Box 687, Jefferson City, MO, 65102; fax: 573-751-7815; e-mail: joe.parks@ dmh.mo.gov. Dr. Parks; Mr. Swinfard; and Dr. Stuve have disclosed no relevant fi nancial relationships. doi: 10.3928/00485713-20100804-08


Accurate alignment of multi-session medical imaging is essential to the analysis of disease progression. By comparing the magnetic resonance imaging (MRI) data captured before and after a course of neoadjuvant chemoradiation (nCRT) treatment, physicians are able to evaluate the tumor response for further treatment of the disease. However, rectal MRI data captured in multi-session are often misaligned and not guaranteed to have one-to-one correspondence, making it challenging for physicians to observe the treatment response of tumor. To address this issue, we propose an unsupervised learning based volume registration framework, which enables accurate alignment even under a high degree of deformation between multi-session rectal data. Moreover, it works without the assumption of one-to-one correspondence between multi-session data, and hence is a general solution to rectal MRI volume registration. The experimental results show that the proposed registration framework accurately aligns rectal cancer images and outperforms other state-of-the-art methods in medical image registration. By providing accurate registration, it can potentially increase the efficiency and reduce the workload for physicians to evaluate the rectal tumor response to nCRT.


The article talks about the author's understanding after attending the provincial education new course conducted by the provincial Education Department and briefly analyzes how higher education in normal art suits new course reform in middle school art in teaching idea in Fujian province.


In this paper, we attempt to gain insights on designing codes for unsourced multiple access by investigating an important special case of a two-user unsourced binary adder channel (2-UBAC). In 2-UBAC the receiver observes a noiseless real sum of two binary vectors. We show several results. First, for a linear code the per-user probability of error (PUPE) equals the fraction of nonminimal codewords, implying that such codes can at most achieve rate-1/2 while capacity of 2-UBAC is 3/4. Second, for sparse-graph codes to jump start an iterative peeling decoder we need to reveal ("pivot") one of the ambiguous symbols. If the pivot is selected randomly then any irregular LDPC code ensemble has a non-vanishing error probability. If the pivot is selected optimally then we show that three regular LDPC code ensembles attain vanishing PUPE: (3, 4), (4, 5) and (5, 6). Our proof does not apply to any other regular LDPC code ensembles, but we believe that they should all have a non-vanishing error probability. Finally, we discuss ideas about (nonlinear) coding to break through the rate-1/2 bottleneck.


Guidelines for the construction, selection and interpretation of measurement devices, David F. Pack and Colin M. Shapiro screening and detection of psychiatric illness, Patricia Casey depression, Max Hamilton and Colin M. Shapiro anxiety, R. Phillip Snaith and Graham Turpin obsessions, compulsions and intrusive cognitions, Paul M. Salkovskis personality disorder and social functioning, Peter Tyrer psychotherapy, Chris P.L. Freeman and Jenny Munroe adjustment to illness, Geoffrey B. Lloyd organic psychiatry, B.E. Berrics psychosis, Eric L.H.M. Van de Loo et al elderly, Chris J. Gilleard and Janice E. Christie drug problems, Susan J. Grey and Michael Gossop people with mental handicaps, Chris Culten and Paul Dickens eating disorders, Chris P.L. Freeman and Fiona Barry sexual behaviour, John Bancroft sleep disorders, Colin M. Shapiro and Katherine Rathouse.


The approach of connecting the customized A/D hardware with the LabVIEW software platform was presented based on dynamic link library function and traditional program language C.


The purpose of this study was to describe the effectiveness of the implementation of "public service plus" programs in Kecamatan Kuranji Padang City. This study described the effectiveness of program implementation seen from the quality of apparatus, administrator competence, facilities and infrastructure, discipline, and supervision. This study was a descriptive research with quantitative approach. The population of this study amounted to 1285 users of public services plus, with a sample of 93 respondents determined by Slovin formula and used random sampling technique. Instrument in this study used questionnaire with Likert scale measurement. Data in this study were analyzed with descriptive statistic. The results of this study indicated that the effectiveness of the implementation of public service plus programs only reached 49.7% and categorized as quite effective. In terms of effectiveness of the implementation of public service programs plus seen from the quality of apparatus, administrator competence, facilities and infrastructure, discipline and supervision, the service program only reached 57.3% and categorized as quite effective.


Over the past decades, we witnessed changes in the matrimonial and parenting institutions. Medical innovations have further created ethical-legal dilemmas. It is, therefore, essential to create a theory and framework that will determine ways to deal with the resulting dilemma in a fully developed manner. This paper surveys the current, conflicting shifts in family structure and the definition of legal parenthood. In it, I deal with the importance and various aspects of defining legal parenthood. I will also focus on the singularity of this dilemma as it is increasingly apparent in the various fertility treatments. I present the sociological-legal roots of the definition of the legal-parenthood dilemma as reflected in various levels of modern family structure over the past fifty years. I further survey the current law accepted models for defining legal parenthood, their central themes, various challenges they must address, and their advantages. This way, I hope to lay the theoretical foundation for a normative model which, in my opinion, will serve as the most coherent, flexible, applicable, and just model for determining legal parenthood by agreement. I will review its main benefits at the end of this article.


A simplified method for calculating investment costs of organic chemical plants from energy input and output data is described. On the basis of this analysis, the general production cost parity condition is deducted for processes that can be based on oil or coal. In addition, a prognosis on the sequence of substitution of coal for oil in different organic processes is attempted. The proposed method is a supplement to, but not a replacement for, conventional methods.


We point out an equivalence between the discrete velocity method of solving the Boltzmann equation, of which the lattice Boltzmann equation method is a special example, and the approximations to the Boltzmann equation by a Hermite polynomial expansion. Discretizing the Boltzmann equation with a Bhatnagar-Gross-Krook collision term at the velocities that correspond to the nodes of a Hermite quadrature is shown to be equivalent to truncating the Hermite expansion of the distribution function to the corresponding order. The truncated part of the distribution has no contribution to the moments of low orders and is negligible at small Mach numbers.


While most countries have imposed austerity policies that risk jeopardizing the progress towards gender equality, there are examples of European regions that have maintained or strengthened gender-equality policies in a climate of economic downturn. Following a realist approach and adopting Kingdon's agenda-setting model as our framework, this explanatory case study examines how, why and under which circumstances the gender budgeting strategy has resisted austerity measures. This strategy represents a key tool for gender mainstreaming in Andalusia, a southern region of Spain. Results have shown that the existence of a strong left-wing government is a necessary context for the maintenance of gender equality policies. The feasibility given by the previous context of institutionalization of this strategy and its low cost, together with political commitment — with a decisive contribution from female leadership — have been the major factors allowing the maintenance of the gender budgeting strategy in Andalusia.


Let G be a k-regular vertextransitive graph with connectivity � (G )= k and let mk (G )b e the number of vertexcuts with k vertices. De-ne m(n; k) = min{mk (G): G ∈ Tn; k }, where Tn; k denotes the set of all k-regular vertextransitive graphs on n vertices with � (G )= k. In this paper, we determine the exact values of m(n; k). c


Artificial neural network(ANN) -- as general tools for implementing nonlinear mapping between inputs and outputs -- is proved to be feasible position estimation for self-sensing active magnetic bearings. A neural network with five neurons in hidden layer is constructed and well trained. With neural network act as position feedback, the active magnetic bearings system performed well. Simulation results show that neural networks can well extract the information of rotor position from the current wave form.


Procedures were devised for the reversible decondensation and recondensation of purified mitotic chromosomes. Computational methods were developed for the quantitative analysis of chromosome morphology in high throughput, enabling the recording of condensation behavior of thousands of individual chromosomes. Established physico-chemical theory for ionic hydrogels was modified for application to chromosomal material and shown to accurately predict the observed condensation behavior. The theory predicts a change of state (a "volume phase transition") in the course of condensation, and such a transition was shown to occur. These findings, together with classical cytology showing loops of chromatin, lead to the description of mitotic chromosome structure in terms of two simple principles: contraction of length of chromatin fibers by the formation of loops, radiating from a central axis; and condensation of the chromosomal material against the central axis through a volume phase transition. One sentence summary The mitotic chromosome is an axially scaffolded ionic hydrogel, undergoing a volume phase transition to achieve a condensed state.


Abstract : This report details a 32 month research project on surface acoustic wave, SAW, two port resonator filters, phase weighted gratings for surface wave resonators, and the equivalent circuit modeling of a thin film stacked crystal bulk wave filter. The report details a new device configuration for coupled two port SAW resonators which would allow the coupling to occur only when the grating reflectors are in resonance and would offer little coupling when the resonator is out of the resonance condition. This configuration is composed of an interdigital electrode transducer, IDT, which is placed within the grating itself but is an IDT whose periodicity is an even multiple of the wavelength. The concept of a phase weighted grating is described for use in wide band resonators. This new concept is based upon the unique properties of gratings and the concept of a movable reflection plane. A simple equivalent circuit for the thin film stacked crystal filter is derived for the first time and results in a lumped element representation for this important device. (Author)


..................................................... iii Acknowledgements............................................... iv List of Terms................................................... v Chapter 1: Introduction......................................... 1 Chapter 2: Embedded Knowledge in the Lands of Eastern Canada... 7 Mi'kma'ki .................................................... 7 Kouwakati: A Place Unearthed ................................ 13 The Ideological Landscape of Dalhousie University ........... 15 Landscape Design for a Renewal of University Boulevard ..... 18 Chapter 3: Resurgence.......................................... 33 Learning and Education from a First Nations Perspective .... 33 Modes of Learning ........................................ 53 A Classroom for Traditional Knowledge ....................... 66 Chapter 4: Architecture of Resurgence.......................... 72 Determination of Program Through Case Study ................. 72 Learning Space as Woven Space ............................... 87 Chapter 5: Refl ection.......................................... 120 Bibliography.................................................. 124


Includes:
1973:
Gay Liberation National Conference. August 25-26 1973, Christchurch. Ilam Student Union, GLF, Box 1717, Christchurch (2 copies)
1974:
Gay Liberation Movement. Gay Liberation National Conference. Out of the closets. Easter 1974. University. Gay Liberation.V.U.W. Stud. Assn. Private Bag, Wgtn. 1974. (2 copies)
1979:
The New Standard. Right now this means lesbians and gay men. "I do not agree that all discrimination should be made unlawful. This would not be reasonable". P J Downey, Chief Human Rights Commissioner [1979] Green poster.(2 copies)
The New Standard. Right now this means lesbians and gay men. "I do not agree that all discrimination should be made unlawful. This would not be reasonable". P J Downey, Chief Human Rights Commissioner [1979] (Copy with two purple stickers, male and female, of the WRAC/NZUSA)
The New Standard. Right now this means lesbians and gay men. "I do not agree that all discrimination should be made unlawful. This would not be reasonable". P J Downey, Chief Human Rights Commissioner [1979] (2 copies)
See the subject location LESBIAN for related material.
Quantity: 4 colour photo-mechanical print(s). 1 b&w photo-mechanical print(s).
Physical Description: Photolithographs on posters, sizes varying around 597 x 420 mm.
Provenance: Donated from various sources


In a production line, the maintenance is a crucial aspect to prevent untimely breakdown as it might lead to decrease in productivity and huge financial losses. This paper presents a concept to develop an integrated intelligent maintenance system for the production line which works when incorporated with an Augmented Reality (AR) device. The overall system will be integrated with the Internet of Things (IoT) for rapid access to varied and arranged information on the AR device. This will provide quick assistance to the users and help in reducing their cognitive load which will in turn help in decreasing the time of maintenance as well as the overall working time of production line.


In view of the current shortages in the multipurpose test- platform and the process of the testing for water pumps, the arti- cle, combining the objects to be controlled and their requirements in the platform and the course of testing, firstly introduces an au- tomatic control scheme of the multipurpose test- platform based on the PLC control and the frequency conversion speeding, then gives the hardware configuration of the PLC and the frequency conversion speeding system, also presents the principle to design software of the PLC control system according to the process requirement of the testing.


Cultivating and lifting the organizational capability of trade association and making it develop continuously and healthily would be of much significance socially,economically and politically.By a brief introduction of Theory of Clubs,Theory of Benefit Group and Theory of Property Rights,the paper,from the perspective of economics,analyzes trade association and properly positions its organizational capability.


Fission yields of twelve mass chains from I4-Mev neutron-induced fission of U/sup 238/ are measured with the following results: A = 89, 2.0%; 90, 3.4%; 91, 2.l6%; 111, yield curve in the region A = 131 to 135 is observed with a distinct peak at A = I32. The data can be explained at least qualitatively, and agrees with the fine structure observed for U/sup 238/ spontaneous fission. (auth)


In this report a method for the numerical solution of the almost incom-pressible Euler equations is described. For this type of ow common numerical methods for compressible ows loose eeciency or do not converge. The method used here for almost incompressible ows is typical for incompressible ow computations: discretisation on a staggered grid in combination with the pressure correction method. When the equations are nondimensionalised in the way described in this paper, this method is expected to give Mach number independent accuracy and convergence. This is connrmed by numerical experiments.


The domain formation process of the photo-induced cooperative low-spin (LS) to high-spin (HS) conversion phenomena are studied based on the Monte Carlo simulation method. The existence of the threshold light intensity and the incubation period are demonstrated. It is pointed out that the nucleation barrier of HS domain is surmounted by the fluctuation caused by the repetition of excitation and de-excitation. By defining an effective temperature for this fluctuation, the time scale of incubation period is estimated following the usual domain formation theory. It grossly accounts the Monte Carlo (MC) results in three-dimensional cases. The phase separation of HS and LS domain is reproduced by considering the volume striction effect. The step wise abrupt conversion is ascribed to the de-pinning of the volume striction.


Emigration countries such as Latvia institutionally should address the negative consequences of the ageing populations' economic and demographic challenges. To this aim, in 2018 network of five regional return migration coordinators was established to foster and nationally encourage return migration. The primary function of the regional coordinator is to foster and facilitate requests of potential return migrants. Drawing on interview materials collected in 2020 with return migration coordinators at the regional level – Latgale, Vidzeme, Zemgale, Kurzeme and Riga, we illustrate good-practice of return migration institutionalisation in Latvia. Our study focuses on three main fields of interest within the work of regional return coordinators: 1) what are the typical return migration paths from the coordinators' perspective? 2) what are the main challenges in coordinators' work? 3) how education-related issues for return migrants are solved? The research reveals that people typically return for family reasons and long for their homeland, traditions, and traditional settings. The research states that the main challenges coordinators' work relates to is the low standardisation level as each returnee's case is unique.


An indirect enzyme-linked immunosorbent assay(ELISA) was established for detection of bovine rotavirus antibodies using bovine rotavirus purified by CsCI density gradient centrifugation as coating antigen.The control antigens prepared with bovine viral diarrhea virus,E.coli,Staphylococcus aureus and Streptococcus agalactia,respectively showed no cross-reaction with negative and positive sera against bovine rotavirus.This result demonstrated that the established method could be used for detection of bovine rotavirus antibodies.


Mary E. Petersen (Figure 1) was born in Nyack, New York, to Charles and Helen Wirtenson on 8 February 1938, and passed away in Damariscotta, Maine on 7 July 2014 at the age of 76 after a battle with cancer. Her childhood and early years were spent in New York State. She received a BA in Art and Zoology from Rutgers University, New Brunswick, New Jersey in 1960 and an MA degree in Zoology and Marine Biology from Duke University, Durham, North Carolina in 1964. At Duke, she was accepted into a PhD programme and completed her course work and various examinations before moving to Denmark in 1965. She received a Mag. Scientist Degree from the University of Copenhagen in 1970. While at Duke, she met and married Kay W. Petersen; they subsequently separated, but Mary remained in Denmark and worked at the Zoological Museum of Copenhagen (ZMUC) as a language and technical editor for various publications including Steenstrupia. Mary was fluent at several levels in eight languages. She was affiliated with ZMUC as a Research Associate in polychaetes from 1965 to 2004. Following discussions and an invitation from Dr Les Watling, Mary retired from ZMUC and moved from Denmark to the Darling Marine Center (DMC), University of Maine in Walpole Maine, USA in December 2004 – where she remained until her death in 2014. At the DMC, Mary was given laboratory space and an honorary title, 'Scholar in Residence', which allowed her to continue her research on polychaetes. Mary Petersen's main interest with polychaete systematics and biology was with the following taxa: Cirratulidae, Ctenodrilidae, Chaetopteridae (mainly Chaetopterus), Fauveliopsidae, Heterospio, Pholoe and Sternaspidae. Her approach to each group was to first determine the availability of type specimens, obtain and examine them, and then compare their morphology with new materials. In this effort she examined most of the types of Chaetopterus and numerous poorly known cirratulids. Unfortunately, the types of certain species were not available and this slowed her efforts, especially when materials from type localities were not available. Much of her effort was directed to supposed cosmopolitan species such as Chaetopterus variopedatus and Chaetozone setosa that with careful study have proven to represent numerous species. For such species, she coined the term 'Characteristic Species Disease' (Petersen, 1984). Mary also used reproductive biology to support her systematic work, especially with cirratuliform polychaetes where asexual reproduction and regeneration is prevalent. She and Dr J.D. George demonstrated that the eight species of an entire ctenodrilid genus, Zeppelina, was based on regenerating specimens of the cirratulid genera Dodecaceria and Monticellina (now Kirkegaardia) and the ctenodrilid genus Raphidrilus (George & Petersen, 1991). She later prepared a comprehensive review of cirratulid sexual and asexual reproduction based on her own observations and a compilation of literature, much of which was obscure (Petersen, 1999a). In August 1986, Drs Mary Petersen and Jørgen B. Kirkegaard hosted the 2nd International Polychaete Conference (IPC) in Copenhagen. Following the Conference, Mary was Guest Editor of the Proceedings, published in Ophelia Supplement 5 (1991), a book with 723 pages that included 67 papers published and 28 new species described by various authors. Mary was also on the editorial board for the 4th IPC and was co-editor of the Deep-Sea Newsletter with Dr Torben Wolff. Mary attended the 1st to 7th and the 9th IPC conferences and presented papers or posters at each one. She also participated in other conferences and workshops devoted to polychaetes (Figure 2). Mary was perhaps best known for her willingness to help other workers by obtaining literature, translating descriptions, reviewing manuscripts, and generally contributing her extensive knowledge of polychaetes. She was often invited to collaborate on various projects. When I was preparing the chapter Fig. 1. Mary Petersen at her home in Maine, August 2007. Photograph courtesy of Vasily Radashevsky.


PURPOSE
Telehealth utilization has increased dramatically over the past few years due to improvement in technology and the COVID-19 pandemic. To date, no study has examined whether a telehealth visit alone for preoperative evaluation is safe and sufficient prior to surgery. We examined the safety and feasibility of preoperative telehealth visits alone prior to minimally invasive urologic surgery Materials & Methods Single institution retrospective review of robotic prostate, kidney, and cystectomy procedures between April - Dec 2020. Cases were dichotomized into those who underwent preoperative evaluation by telehealth-only versus traditional in-person visits. Outcomes included complications, blood loss, conversion to open surgery rates, and operative times. We assessed efficiency of care by measuring time from preoperative visit to surgery. Results 314 patients were included in the study, with 14% of cases (n = 45) being performed after a preoperative telehealth visit. The majority of cases included in analysis were robotic surgeries of the prostate (56.1% of all cases, n = 176) and the kidney (35.0% of all cases, n = 110). Patients seen via telehealth alone preoperatively had no significant differences in any grade of complications, perioperative outcomes, blood loss, operative time, and length of stay. There was no difference in change in anticipated procedure between groups, and there was no cases of conversion to open surgery in the telehealth only group. Time from preoperative visit to surgery was significantly shorter for the telehealth group by 13 days. Conclusion Our study is the first to analyze the safety of telehealth-only preoperative visits prior to minimally invasive urologic surgery. We found no difference in perioperative outcomes including conversion to open surgery or change in planned procedure. Further, telehealth preoperative visits appeared to facilitate shorter time to surgery. This study has important implications for expediting patient care and medico-legal considerations.


Background: MicroRNAs have critical roles in T cell development under normal and stress conditions. Results: Increasing miR-185 levels attenuate T cell development via the targeting of Mzb1, NFAT3c, and Camk4. Conclusion: Elevations in miR-185 impair thymopoiesis at several developmental stages. Significance: MiR-185 levels are reduced in 22q11.2 deletion syndrome patients and the identification of its gene targets is clinically informative. ABSTRACT MiR-185 is a microRNA (miR) that targets Bruton's tyrosine kinase in B cells, with reductions in miR-185 linked to B cell autoantibody production. In hippocampal neurons, miR-185 targets both Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 and a novel Golgi inhibitor. This miR is haploinsufficient in 90-95% of individuals with chromosome 22q11.2 deletion syndrome, patients


In tokamaks, baking of vacuum vessel and first wall components is a prerequisite in order to obtain impurity free pure plasmas. Baking is performed to remove various kinds of impurities such as H2O, Carbon and Oxygen from the v essel wall and first wall components. ADITYA tokamak has been recently upgraded ADITYA-U tokamak to achieve shaped plasmas [1]. The Aditya U tokamak is equipped with a comprehensive baking system for baking the stainless steel v acuum vessel, pumping systems & associated diagnostic systems along with the graphite limiter and diverter tiles up to 150 C. T h e DC Glow discharge cleaning is also carried out in presence of baking to achieve better wall conditions for high performance plasma discharges in the machine. The structure of the Aditya Upgrade vacuum v essel is quite complex, with ~ 111 standard and customize port openings [2]. The baking of the vessel is carried out by positioning the current carrying filament heat in g elements around it . Due to space limitation between vessel and toroidal magnetic coils in the high-field (in-board) side, 1.5 mm thick silicon heaters has been designed and procured from M/s. Marathon Heaters, India. In -situ Installation of h eat er s has been quite challenging due to structural complexity of vacuum vessel. For efficient heat insulation, 6 mm thick silicon jacket designed and fabricated according to vacuum vessel profile and installed on vacuum vessel. A detail analysis has been carried in ANSYS for its optimum performance and to examine its effect on vacuum vessel, especially on the several weld joints. Whole baking system consists of ~ 80 heaters installed on different sectors of the vacuum vessel, pumps and diagnostics. The heaters are controlled in close loop by a Programmable Logic Controller (PLC) based automatic baking control system, which is developed in house. It comprises of three main phases, temperature ramp -up phase, constant heating phase (~ 150 C) and rampdown to room temperature phase. All these phases are individually controlled as required. The complete baking system has been tested thoroughly for its automatic operations for long hours (~48 Hours), integration, ruggedness, reliability, small form factor before integrating it to tokamak operation system for regular long-hour operation s. It also has been optimized for cost effectiveness. The detailed hardware concept, software design and prototype testing results and its regular operation in presence and absence of GDC will be discussed in this paper. Partial pressure of impurity gases is monitored in every baking cycle which decides and controls the baking temperature and duration automatically. Further, the potency of lithiumization carried out before, during and after baking has been compared for the first t ime in Aditya-U tokamak by estimating the lithium lifetime on the walls with plasma operation. The observation of conditioned vacuum vessel and effect of baking with different temperatures and durations on overall plasma performance along with technical challenges faced during installation, commissioning of baking system in Aditya-U will be presented in this paper.


Confronted with a fait accompli by the ratification of the ECSC Treaty in 1951, the biggest German metalworkers' organization – IG Metall – initially came to the conclusion, not to support the foundation of the new community. However, switching to the year 1957, when the Treaties of Rome marked the next step of European integration, this position became significantly modified: IG Metall was not merely participating in all the trade unions related ECSC structures, but rather drew the conclusion, that the ECSC has been an economic success and that integration should be deepened. Reviewing the development of this change and its reasons, this article states that IG Metall had undergone a process of Europeanization.


The study was funded by Spanish projects BIO2005-03569, AGL2005-01748 and CTQ2005-08925-C02-02, EU project QLK3-99-590, and ENCE-CSIC contracts. Beldem (Andenne, Belgium) is acknowledged for the laccase sample.


This article investigates the sense of place experienced by individuals living in the nested "ontic"' district of north County Louth, Ireland, the place where its author was born and raised. The sense of place experienced in north Louth-known locally as "The Cuchulainn Country"-is particularly interesting, for it is characterized by frequent reference to the ancient Irish saga Tdin B6 Cuailnge (The Cattle Raid of Cooley), which scholars hitherto claimed never to have entered modern tradition.2 When an individual's experience of life in a particular locality becomes encoded by a combination of meaningful landmarks and memorable human events peculiar to that place, that person has achieved a sense of place. Writing about individual identity and folklore, Dundes notes that traditional forms of self-identification-such as flyleaf inscriptions found in books-expand outward from the individual through a series of identity sets toward the idea of the totality of existence (Dundes 1983:135). While many features of identity in this unfolding process can and do fluctuate, the element of place is a fairly stable one, indicating its deep significance in human life


The kinetics of bactericidal activity of the methanolic extracts of powdered seeds of Garcinia kola (Heckel), Kola acuminata and Kola nitida obtained by soxhlet extraction, were studied using two bacterial sensitive strains of Staphylococcus aureus and Pseudomonas aeruginosa. The study showed that the three extracts at the concentrations used against the two test organisms, Staphylococcus aureus OOUTH206 (0.5mg/ml for Garcinia kola, 4mg/ml for Kola acuminata and Kola nitida) and Pseudomonas aeruginosa UCH189 (8mg/ml for Garcinia kola, 15mg/ml for Kola acuminata and Kola nitida); had activity on the two microorganisms. There was a gradual reduction in the number of viable microbial counts as evident in the reduction in the cell number at the different time intervals. Similar procedure was carried out in the presence of 5% serum protein and it was observed that the activities of the various extracts were altered significantly indicating the effect of serum protein binding on the constituents of Garcinia kola, Kola acuminata and Kola nitida seed extracts. The results were expressed in percentage viable count of the inoculum size and showed that the percentage viable count decreases with time in varying degrees. The reduction was more intense with G. kola extract than the other extracts on S. aureus as well as on P. aeruginosa towards the third and fourth hours. The effect of serum protein was seen to affect the activities of all the extracts in varying degrees as shown in the graphs plotted. Key words: Garcinia kola , Kola acuminata , Kola nitida , methanolic extracts, respiratory tract infections, serum proteins.


Reversing treatment-related premature ovarian failure by means of autotransplantation of frozen-thawed ovarian tissue harvested before chemo-radiotherapy is becoming an increasingly realistic prospect for clinical application, with 30 live births already reported using this technique. Our objective is to offer young patients at risk of post-treatment premature ovarian failure safe fertility preservation options.


Zirconia-based composites with high thermochemical stability and electrochemical activity are the most promising solid electrolytes for manufacturing solid oxide fuel cells (SOFCs). In the present work, nanocrystalline composite powders of gadolinium-doped zirconia (GDZ: Gd2xZr2(1−x)O4−x) with various doping fractions (0.01 ≤ x ≤ 0.16) were synthesized by the Pechini method and applied for the fabrication of several electrolyte pellets to evaluate their physicochemical properties, sinterability, and conductivity. The X-ray diffraction (XRD) patterns and the thermogravimetry/differential thermal analysis (TGA/DTA) of the synthesized powders confirmed the successful formation of nanocrystalline GDZ in the tetragonal phase with complete substitution of gadolinium phase into the zirconia (ZrO2) lattice. The synthesized gadolinium zirconate powders were then shaped into pellet forms using the tape casting method, followed by sintering at 1300 °C (for 2.5 h). The microstructural analysis of the electrolyte pellets showed suitable grain boundary welding at the surface with an acceptable grain growth at the bulk of the T-phase GDZ samples. The impedance measurements indicated that the T-phase GDZ-8 could provide a comparably higher ionic conductivity (with 7.23 × 10−2 S/cm in the air at 800 °C) than the other dopant fractions. The results of this work can help better understand the characteristics and electrochemical performance of the T-phase gadolinium zirconate as a potential electrolyte for the fabrication of SOFCs.


Generic Science Skills (GSS) are the ability to think and act based on the knowledge possessed by individuals. Every human being has generic science skills that need to be developed along with the development of the human brain. This is because generic science skills can be developed in accordance with the development of the level of human thinking. After the COVID-19 pandemic, teaching and learning activities experienced changes in the learning process. This resulted in learning originally carried out in the network (online) turning into offline learning (offline). Biology is a science that allows students to discover for themselves the concepts and facts contained in the biology material. Finding concepts in biology requires direct observation of biological objects. This study aimed to describe generic science skills among class X students at SMAN 1 Daha Utara. The research was conducted using a descriptive method. The description of students' generic science skills was obtained from filling out the questionnaire distributed to students. The generic science skills questionnaire used uses aspects that refer to Brotosiswoyo in 2001, which contain direct observation, indirect observation, awareness of scales, symbolic language, a framework of mind obeying the principles of natural law, logical inference, the law of cause and effect, mathematical modeling, and building the concept. This study took the population of all class X students of SMAN 1 Daha Utara. The sample for this study took 98 students randomly from six classes, namely classes X1-X6. This study uses data analysis techniques that are carried out by categorizing test results based on low, medium, and high categories. Based on the results of this study, it appears that students' generic science skills are included in the high category.


Due to the problems of unbalanced data sets and distribution differences in longterm rainfall prediction, the current rainfall prediction model had poor generalization performance and could not achieve good prediction results in real scenarios. This study uses multiple atmospheric parameters (such as temperature, humidity, atmospheric pressure, etc.) to establish a TabNet-LightGbm rainfall probability prediction model. This research uses feature engineering (such as generating descriptive statistical features, feature fusion) to improve model accuracy, Borderline Smote algorithm to improve data set imbalance, and confrontation verification to improve distribution differences. The experiment uses 5 years of precipitation data from 26 stations in the Beijing-Tianjin-Hebei region of China to verify the proposed rainfall prediction model. The test set is to predict the rainfall of each station in one month. The experimental results shows that the model has good performance with AUC larger than 92%. The method proposed in this study further improves the accuracy of rainfall prediction, and provides a reference for data mining tasks.


Objective: To evaluate the functional outcome of the Triceps Tongue Lift Approach for distal humerus type C fractures in adults.
Methodology: Twenty-two cases (16 males and 6 females) of distal humeral fractures were included in this prospective study conducted between January 2015 to January 2017. The study was conducted at services hospital, Lahore, Pakistan. The average age was 45 years (range 35-54). Open reduction and internal fixation were performed in all cases. A triceps tongue lifting approach was used and parallel plating technique was chosen for all fractures. The elbow was splinted with back slab, which was removed after 3 weeks of operation. Rehabilitation was started on the next day of operation. Patients were called for follow up at 1, 2, 4, 6 and 12 months during which complete history, physical examination and radiographs were recorded. Completion of Disabilities of Arm, Shoulder and Hand (DASH) questionnaire, Recording of Range of motion at elbow joint, and Objective Muscle Strength Testing (MRC Grade) of triceps muscle were done.
Results: Out of 22 patients, 16(72.7%) were male and 6(27.3%) female with the mean age of 45.0±5.8 years. The mean duration of follow up was 16.8±4.5 months (Range 8-24). Mean flexion contracture was 10.5˚±7.8˚ and mean arc of flexion extension was 111.8 ˚±19.7˚. The mean DASH score at final follow up was 7.0±0.6, indicating mild residual impairment.
Conclusion: A tricep tongue lifting (V-Y plasty) approach is an excellent approach to provide adequate exposure to the joint, and provides good functional outcome, complete range of motion at elbow joint and almost complete recovery of triceps muscle power.


This paper presents the use of self similarity with random variations and probabilistic growth of branches as the basis of generating natural forms of trees. Bifurcation branching geometry has been considered as the fundamental element in the formation of tree structures and Honda's model was used to generate the recursive branching patterns. In order to simulate the dynamic variations of natural trees, the model was extended by introducing random variation to control the branch lengths and branching angles at each stage. The probabilistic occurrences have been introduced to control the formation of new branches. The resultant tree structures show that the addition of random variation and the introduction of probabilistic occurrence of branches have made a greater impact to the generation of visually convincing natural tree structures. J.Natn.Sci.Foundation Sri Lanka 2013 41 (3): 229-235 DOI: http://dx.doi.org/10.4038/jnsfsr.v41i3.6058


Objective To evaluated diagnosis yield of cytological and histological analysis of endo- scopic ultrasound guided fine needle aspiration (EUS-FNA). Methods A total of 43 patients who were clinically diagnosed as having mediastinal lesions, retroperitoneal lesions or pancreatic lesions by CT were re- cruited to the study. EUS-FNA was performed with standard 22G needle. Specimens were placed in formalin for histological analysis, and residual materials were prepared for cytologic analysis. Results Lesions were located in the mediastinum ( n = 9 ) , the retroperitoneum ( n = 1 ) , and pancreas ( n = 33 ). Cytologic diagno- ses included malignancy ( n = 22 ) , suspicious malignancy ( n = 2 ) , atypical cell ( n = 3 ) , absence of malig- nancy ( n = 16). Histologic diagnoses included malignancy ( n = 30), suspicious malignancy ( n = 1 ), sar- coidosis ( n = 2) , chronic inflammation ( n = 10). The positive rates, sensitivities and accuracies of cytology and histology were 51%, 59% , 65% and 74% , 81% , 84% , respectively. Conclusion The positive rate, sensitivity and accuracy of histology of EUS-FNA is superior to cytology.

Key words:
Endoscopy ultrasonography;  Biopsy,fine-needle ;  Cytology;  Histology


Ideally a study of cell proliferation with tritiated thymidine (3H-TdR) should be carried out in the intact animal. Cell cycle compartment times, such as DNA synthesis time (T,), can be examined by means of the per cent labeled mitoses method or if, as in human beings, conditions do not warrant repeated biopsies, by the in uiuo, in uitro double labeling method. Although human lymphocytes are usually available for experimentation (blood, tonsils, adenoids, appendix, spleen, etc.), it is a rare situation indeed when in uiuo kinetic studies can be performed on these cells. Initial results of a completely in uitro measurement of the T, of bone marrow cells (Lala, Maloney & Patt, 1965) were not encouraging, but a subsequent report on erythroid cell T , in bone marrow (Kesse-Elias, Harris 8z Gyftaki, 1967) has prompted a restudy of the problem. Fabrikant (1970) has recently developed a novel method for measuring T, completely in uitro. Lymphocytes were chosen because uiuo-uitro double labeling studies were in progress (Schiffer, 1971). Fresh tonsils from young patients were finely minced in 10 pCi/ml 3H-TdR (specific activity 1.9 Ci/mM) in McCoy's medium 5A and incubated for 45 min at 37°C. Half the resulting cell suspensions was then reincubated for 30 min with 3 4 pCi/ml 14C-TdR (specific activity 50 mCi/mM) in the same medium. Slides were prepared for double emulsion autoradiography as previously reported (Schiffer, 1971). Two thousand labeled cells were counted in each specimen and were classified as I4C labeled or 3H-only labeled. T, was calculated by the relationship:


The relationship between a party leadership and party activists is often illustrated by the use of John May's "Law of curvilinear opinion structures in political parties", i.e. the idea that mid-le ...


Throughout this century, and before, efforts have been made to instruct physicians and scientists in ways to improve their professional writing. Instructors have lectured, conducted workshops, and written articles and books. If the results have been meager, it is not for want of champions. One of these has been Morris Fishbein. He first published this book in 1938; now it appears in the 4th edition, and continues to offer much practical advice in a wide variety of areas. In broad terms, the book provides guidance on the construction of the manuscript as a whole and also discusses the individual units of the manuscript. Thus there are useful chapters on construction, preparation, and revision of the manuscript (which, incidentally, are scattered through the book and might logically be brought together in one section). Additional chapters are addressed to such topics as spelling, capitalization, abbreviations, illustrations, and proofreading. Throughout, the assiduous reader


AbstractSuperparamagnetic starch-functionalized magnetite nanoparticles (SMNPs), ranging from 6 to14 nm, were prepared by a co-precipitation synthesis protocol. The SMNPs were used as nanoadsorbents for the removal of Cr(VI) from aqueous medium by the batch adsorption technique. The SMNPs adsorption capacity was found to decrease with the increase in the pH of the Cr(VI) solution. Under optimum pH conditions, the maximum experimental adsorption capacity of SMNPs for Cr(VI) was found to be 26.6 mg g−1. While the adsorption was endothermic, the equilibrium adsorption data could be best fitted to the Freundlich adsorption isotherm model and its kinetics was in agreement with the pseudo-second-order rate equation. The SMNPs could be easily regenerated because of low adsorption activation energy. The SMNPs capacity for Cr(VI) removal remained almost undiminished even after its repeated use.


The chemical and elemental constituents of Vernonia amygdalina and Azadirachta indica leaves were investigated. Phytochemical analysis was determined by the methods of Association of Analytical Chemists (AOAC). The trace elements and macronutrients concentrations of both samples were determined using Atomic Absorption Spectrometer (AAS). Vernonia amygdalina leaves recorded significantly (p<0.05) higher levels of flavonoids, saponins and caroteinoids while Azadirachta indica leaves had higher levels of alkaloids, glycosides, phenols and steroids. Vernonia amygdalina also recorded higher concentrations of zinc, iron, and manganese while there were higher levels of nickel, molybdenum, cobalt, silicon and lead in the leaves of Azadirachta indica. There were higher levels (mg/100g) of potassium, sodium and phosphorus in Azadirachta indica which recorded 0.843 ± 0.019, 0.301 ± 0.047 and 0.280 ± 0.002 respectively with corresponding values in Vernonia amygdalina as 0.710 ± 0.016, 0.334 ± 0.006 and 0.382 ± 0.006. The results showed that both leaves contained varying concentrations of chemical, elemental and macronutrient components. They can serve as good sources of useful elements. The leaves of Vernonia amygdalina could have better anti-oxidant properties than Azadirachta indica leaves.


With the aim of understanding how the magnetic properties of active regions (ARs) control the eruptive character of solar flares, we analyze 719 flares of Geostationary Operational Environmental Satellite (GOES) class ≥C5.0 during 2010–2019. We carry out the first statistical study that investigates the flare-coronal mass ejection (CME) association rate as a function of the flare intensity and the AR characteristics that produce the flare, in terms of its total unsigned magnetic flux (ΦAR). Our results show that the slope of the flare–CME association rate with flare intensity reveals a steep monotonic decrease with ΦAR. This means that flares of the same GOES class but originating from an AR of larger ΦAR, are much more likely to be confined. Based on an AR flux as high as 1.0 × 1024 Mx for solar-type stars, we estimate that the CME association rate in X100-class "superflares" is no more than 50%. For a sample of 132 flares ≥M2.0 class, we measure three nonpotential parameters including the length of steep gradient polarity-inversion line (L SGPIL), the total photospheric free magnetic energy (E free), and the area with large shear angle (A Ψ). We find that confined flares tend to have larger values of L SGPIL, E free, and A Ψ compared to eruptive flares. Each nonpotential parameter shows a moderate positive correlation with ΦAR. Our results imply that ΦAR is a decisive quantity describing the eruptive character of a flare, as it provides a global parameter relating to the strength of the background field confinement.


Discussing BVD with clients in terms of milk losses and economic impact is not always easy. The new Advance study aimed to contextualise losses related to unseen BVD in a milking herd, which is oft...