Mobile apps bring unprecedented levels of convenience, yet they are often buggy, and their bugs offset the convenience the apps bring. A key reason for buggy apps is that they must handle a vast variety of system and user actions such as being randomly killed by the OS to save resources, but app developers, facing tough competitions, lack time to thoroughly test these actions. AppDoctor is a system for efficiently and effectively testing apps against many system and user actions, and helping developers diagnose the resultant bug reports. It quickly screens for potential bugs using approximate execution, which runs much faster than real execution and exposes bugs but may cause false positives. From the reports, AppDoctor automatically verifies most bugs and prunes most false positives, greatly saving manual inspection effort. It uses action slicing to further speed up bug diagnosis. We implement AppDoctor in Android. It operates as a cloud of physical devices or emulators to scale up testing. Evaluation on 53 out of 100 most popular apps in Google Play and 11 of the most popular open-source apps shows that, AppDoctor effectively detects 72 bugs---including two bugs in the Android framework that affect all apps---with quick checking sessions, speeds up testing by 13.3 times, and vastly reduces diagnosis effort.


Abstract : The goal of this award was to identify cytoplasmic proteins that associate with the cytoplasmic tail of PSMA. Using yeast tow-hybrid screening, we identified that PSMA associates with an actin cross-linking proteins called filamin. We have demonstrated this interaction both in vitro and in vivo. We also established that PSMA is localized to he recycling endosome and that PSMA association with filamin is necessary for PSMA targeting to the recycling endosome. Finally, we also showed that the cytoplasmic tail of PSMA through its association with the act in cross-linking protein modulae the NAALADase activity of this protein. We suggest that the cytoplasmic tail of PSMA plays an important role in the function/s of PSMA.


Magnetic tracking technology is emerging to provide an occlusion-free tracking scheme for the estimation of full pose of various instruments. This brings substantial benefits for intra-corporeal applications, such as tracking of flexible robots or wireless endoscopic devices, and thus is helpful for further computer-assisted diagnosis, interventions, and surgeries. Towards efficient magnetic tracking, we propose a magnetic localization and orientation system in this paper. By modeling the cylindrical magnet, the magnetic models have been compared and analyzed. Moreover, we present a sensor layout strategy based on grid method and its optimization method for better performance. Based on the magnetic model and the layout optimization results, we have built a sensor array for magnetic positioning. Extensive simulations and experiments have shown the feasibility of the proposed system with the average positional and orientational errors of  $1.4 mm$  and 3.4°, respectively.


Nowadays silver nanoparticles (AgNPs) synthesized so often by plant extracts as a reductor. The synthesis of AgNPs was carried out by Citrus microcarpa Bunge fruit peel extract a reductor in various extract concentrations (10, 15, and 20%), concentration of AgNO3 solution of 0.15M and temperature of 700C. The presence of AgNPs was determined by color test and the formation of Surface Plasmon Resonance (SPR) using UV-Vis Spectrophotometer while to determine the morphology and size of the nanoparticles using Scanning Electron  Microscope (SEM). The results of the analysis showed that AgNPs was formed at colloidal phase with dark brown color with wavelengths of 457.30 nm, 478.90 nm, and 422.80 nm for variation concentration of 10, 15 and 20% with slightly spherical, slightly elongated and jagged morphology with average size of 253.8 nm (10%), 254.2 nm (15%) and 253.9 nm (20%).


This article aimed to analyze lifetime and past-year victimization and polyvictimization experiences in adolescent outpatients from a southern European country. The sample included 149 adolescents (35.6% boys, 64.4% girls), aged 12 to 17 (M = 14.28, SD = 1.45). Experiences of victimization were assessed using the Juvenile Victimization Questionnaire (JVQ; Finkelhor, Hamby, Ormrod, & Turner, 2005). Results showed that 99.3% of those interviewed had experienced at least one type of victimization during their lifetime, and 84.6% reported past-year victimization. Gender and age differences were found. Based on community criteria, the proportion of polyvictims in the sample was 32.2% for lifetime victimization and 20.1% for past-year victimization. When assessing children in the context of outpatient mental health services, it is essential that clinicians explore any history of exposure to violence, as this information is crucial in determining the young person's therapeutic needs.


This article analyzes the divergences pervading the debate between two contemporary liberal legal philosophers, namely Ronald Dworkin and Jeremy Waldron, about the relationship between democracy, tolerance and religious hate speech. On the one hand, Dworkin argues that any attempt to impose limits on religious hate speeches violates the fundamental right to freedom of speech and therefore affects the democratic legitimacy. Waldron, on the other hand, contends that legal restrictions on hate speech are needed to ensure that intolerance not undermines the democratic principles and values. The ultimate aim of this paper is to evaluate to what extent Dworkin's and Waldron's proposals can provide satisfactory answers to the relationship between religion, democracy and tolerance.


Click-Through Rate (CTR) prediction plays a core role in recommender systems, serving as the final-stage filter to rank items for a user. The key to addressing the CTR task is learning feature interactions that are useful for prediction, which is typically achieved by fitting historical click data with the Empirical Risk Minimization (ERM) paradigm. Representative methods include Factorization Machines and Deep Interest Network, which have achieved wide success in industrial applications. However, such a manner inevitably learns unstable feature interactions, i.e., the ones that exhibit strong correlations in historical data but generalize poorly for future serving. In this work, we reformulate the CTR task --- instead of pursuing ERM on historical data, we split the historical data chronologically into several periods (a.k.a, environments), aiming to learn feature interactions that are stable across periods. Such feature interactions are supposed to generalize better to predict future behavior data. Nevertheless, a technical challenge is that existing invariant learning solutions like Invariant Risk Minimization are not applicable, since the click data entangles both environment-invariant and environment-specific correlations. To address this dilemma, we propose Disentangled Invariant Learning (DIL) which disentangles feature embeddings to capture the two types of correlations separately. To improve the modeling efficiency, we further design LightDIL which performs the disentanglement at the higher level of the feature field. Extensive experiments demonstrate the effectiveness of DIL in learning stable feature interactions for CTR.


were increasingly drastic. The right of drug stores to handle alcoholic stock was taken away. Court officers were given inquisition powers which made it possible to obtain convicting evidence. Repeated violation of liquor laws was made cause for penitentiary sentence. The climax came with the passage of the &dquo;bone dry&dquo; act which made mere possession of intoxicating liquor prima f acie evidence of violation of the Kan-


The aim of the present study was to optimize effervescent floating tablets of Cefixime Trihydrate as model drug by optimization of polymers concentration using central composite design. Mean dissolution time (MDT), time required to release 50% of drug ( t 50% ), drug release at 2 h ( R 2h ) and dissolution efficiency in 2 h (DE 2h ) were taken as target responses, where as the quantity of different polymers such as Carbopol 934P (viscoelastic agent), Sod.CMC (swelling agent) were considered as independent variables. A second-order polynomial equation was determined by the multiple regression analysis of the experimental data. The best fitting model was selected based on the comparisons of the coefficient of determination (r 2 ), adjusted coefficient of determination (adj. r 2 ). In addition, analysis of variance (ANOVA) was used to evaluate the statistical significance of the quadratic polynomial model. The optimum values for the critical components were obtained as 13.151% Carbopol 934P and 4.08% of Sod.CMC with predicted value of 4.926 h MDT, 5.257 h t 50% , 27.6316% R 2h and 16.5951% DE 2h from desirability and overlay plot. Further the reliability of the model was checked by validating the observed responses from optimized formula. The drug release from characteristics of all formulations followed Higuchi model with a non-Fickian diffusion mechanism. Further the data of FTIR study showed there was no interaction of drug and excipients used for the preparation of floating tablets. Key words: Central composite design, Cefixime Trihydrate, Mean dissolution time, Fickian diffusion, dissolution efficiency


The time-averaged enthalpy flow <\dotH> into the second-stage expansion space was evaluated by analyzing the measured pressure in the second-stage expansion space and temperature in the tube connecting the regenerator and the expansion space. Pb and Cu particles with diameters ranging from 0.2 to 1.0 mm were chosen as the second-stage regenerator materials. <\dotH> was calculated as a function of operating temperature for all these regenerator materials. It was found that the magnitude of <\dotH> always increases with decreasing operating temperature, and that <\dotH> strongly depends on both the specific heat and the diameter of the particles. We clearly show how <\dotH> depends on these two parameters by analyzing the temperature profile in the second-stage regenerator. Heat loss <\dotQloss> was also evaluated by taking the energy balance in the second-stage expansion space into account.


Using a vector multiplier, in conjunction with a Motorola M6800 microprocessor, a digital filter section has been implemented. The implementation has added flexibility to the vector multiplier as well as giving sampling rates in the region of 20 000 samples/s.


Although it is recognised that the prevalence ofurinary incontinence increases with age,' it is not known whether this is mirrored by a similar increase in referral for urodynamic studies. The aim of this study was to determine the association with age of referral patterns and urodynamic diagnoses in women with urinary incontinence.


We are interested in a group of species, animal or plant, which, for various reasons, are threatened. They may thus disappear in the more or less near future. For example, the IUCN (International Union for Conservation of Nature) Red List provides information on whether or not a given species is threatened. This list classifies threatened species into three categories, according to their level of extinction risk: "Vulnerable", "Endangered", and "Critically Endangered". This classification is made taking into account various factors such as the population size of the species in question, the rate of decline of this population, the loss and/or fragmentation of its habitat or its genetic erosion. It is also possible to look at a set of focal species, threatened or not, as their protection automatically leads to the protection of many other species. It should be noted that many species, although common, are also in decline and this should be reversed. We are also interested in a set of geographical zones, spread over a territory, that we can decide whether or not to protect, from a given moment on, in order to ensure a certain protection for the species in question and thus increase their chance of survival. The terms "sites", "parcels", "patches", "tasks", "areas", and "islets" are also used to designate these parts of territory. In this book, we will essentially use the term "zone" which, because of its generality, is appropriate in many contexts. The focus here is on species protection, but all of the following could easily be adapted to other threatened aspects of biodiversity such as valuable habitats. In sections 1.2–1.5 of this chapter, it is considered that there is only one level of protection for the zones. In other words, a zone is protected or not. Decisions on protective actions to be taken at the beginning of the time horizon (e.g., 10 years, 50 years or 100 years) are made at the beginning of this horizon, at which time the candidate zones are in a certain state. Protecting a zone has a cost. It differs from one zone to another and may include monetary, ecological and social aspects. We can look at the consequences of these decisions at the end of this horizon. For example, it can be assumed that a given species in a protected zone survives at the


The crystals of (OC-6–13)-(acetonitrile-N)trichlorobis(triphenylphosphine-P)rhenium(III), [ReCl3(C2H3N)(C18H15P)2], contain distorted octahedral molecules in which the phosphine ligands are trans with respect to one another and the Cl ligands adopt a meridional arrangement. In contrast to the isostructural [OsCl3(PPh3)2(CH3CN)] complex, where the Os—Cl distances do not differ greatly, the Re—Cl bond trans to the nitrile ligand [2.393 (2) A] is appreciably longer than the mutually trans Re—Cl bonds [2.344 (2) and 2.350 (2) A].


It is well understood at the moment that most young stars (those younger than 10' y) were formed in large molecular clouds. However, the mean densities of molecular clouds are not high enough to form stars. Some kind of compressing mechanism is needed to produce a star-formation process. It is generally believed that there are three triggering mechanisms for star formation: (1) compression by density wave, (2) compression by the expanding gas of supernovae, and (3) compression by the radiation of 0and B-type stars. To find out which mechanism is dominant, one should study those regions where the stars are very young. The Orion region is one of the youngest. Moreover, since it is a t high galactic latitude and is near the Sun, we are able to obtain many kinds of good data. In this paper, we will discuss results obtained from photographic observations of the stars in the Orion region.


An efficient and compact concentrator Fresnel concentrator is discussed and designed,The central region is a conventional Fresnel lens designed according to Snell's law of refraction,The edge region is designed to be TIR (internal total reflection) prism.According to the Fresnel formula,the best segmentation position and the optimum focal length of two kinds of lens are calculated,and use SolidWorks to build 3D model,The ray tracing simulation of the designed lens is carried out by using TracePro software.The results show that the efficiency is 89.6% and the F/# is 0.5 at high concentration. The efficiency of the traditional Fresnel concentrator is only 66% when the F/# is the same. The design goal of compact structure and high light performance is achieved.


Ebony wood, the black heartwood of trees in the genus Diospyros, is a high-value commodity of many Pacific Islands. The revenue earned from the sale of ebony carvings is important for many low-income rural communities, resulting in high harvesting pressure and reported declines of ebony-producing species. This study investigates the impact of ebony wood harvesting on species of Diospyros on Vangunu Island, Western Solomon Islands. Diospyros samoensis, locally known as 'rihe', was the main source of ebony wood, with D. vera occasionally harvested but producing poorer quality wood. For D. samoensis, we investigated the existing ethnobotanical knowledge and harvesting dynamics using questionnaires and surveyed 11 populations using five 15 × 15 m plots. Although D. samoensis was common throughout the study area, trees with harvestable ebony heartwood were considered rare. The sale of ebony carvings contributed substantially to the livelihood of carvers. Harvesting practices cause considerable damage to the stem and appeared to alter population structure, with fewer seedlings found in stands with higher harvesting intensities (r = −0.704, P = 0.008). Therefore, populations of D. samoensis appear to be negatively impacted by current harvesting practices, which should be modified to (1) cause less damage to individual trees and populations, and (2) protect larger and older trees to help regeneration. Therefore, the increasing rarity of ebony heartwood in the Pacific may not equate to dangerous declines in Diospyros species and implementing low-impact harvesting practices could help improve the health and long-term persistence of Diospyros populations.


Proved the possibility of using amorphous aluminosilicate as a modifying agent for the adhesive dry mixes. Are given the data on the microstructure and chemical composition of the amorphous aluminosilicates. Installed , that the microstructure of the synthetic additives is characterized by particles of round shape, dimensions 5,208-5,704 μm, Also there are particles of elongated shape in size 7.13-8.56 μm. Predominate chemical elements O, Si, Na, S, and Al in quantity 60.69%, 31.26%, 24.23%, 18.69% and 8.29% respectively. Described the character changes in the rheological properties of cement-sand mortar, depending on the percentage of additives. Determined, that the introduction in the cement-sand mortar the additive based on amorphous aluminosilicate leads to higher values of plastic strength. Are given the model of cement stone strength using synthetic additives in the formulation. The results of the evaluation of the frost resistance of cement-based tile adhesives with the use of amorphous aluminosilicates as a modifying additive are presented. In the article is determined the mark on frost resistance of tile glue and frost resistance of the contact zone of tile glue. The evaluation of the performance properties of the layer of tile adhesive on the basis of cement, dry mixes. The calculation of the value of displacement of the adhesive layer made on the basis of the developed recipes cement dry mixes applied to a vertical surface. Experimental data obtained values of displacement tiles relative to the substrate. Described the results of physical and mechanical properties of tile adhesive made on the basis of the developed adhesive dry mix formulations.


A process for producing power from a sour gas comprising H2S, the process comprising the steps of: (a) providing a sour gas stream comprising natural gas and H2S to an acid gas removal unit, resulting in a cleaned natural gas and a acid gas comprising H2S; (b) combusting the cleaned natural gas stream with an oxygen containing gas in a gas turbine to produce power and a hot flue gas; (c) sending the hot flue gas to a first heat recovery steam generator to generate steam and a clean flue gas; (d) combusting at least part of the H2S in the acid gas comprising H2S in the presence of an oxygen containing gas to obtain a hot gas effluent comprising S02; (e) sending the hot gas effluent comprising S02 to a second heat recovery steam generator to generate steam and a cooled gas effluent comprising S02; ; (f) leading the cooled gas effluent comprising S02 to a sulfuric acid unit to produce sulfuric acid, steam and a cleaned flue gas stream.


As part of the qualification materials to apply for RoboCup 2019, this paper describes the most recent improvements made by the CAMBADA Middle Size robotic soccer team. During the last year, improvements have been made in a significant number of components of the robots. The most important changes include redesign of the vision system, design and adoption of an Ethernet gateway among all hardware modules, model adjustment of the ball handling mechanism, conclusion and release of the new RtDB v2, improvements on the vision color calibration and distributed leader election technique, further developments on the set-play engine and the release of the Wi-Fi Monitor and analyser tool for MSL.


The invention discloses a paper giving and overlapped-paper separating controlling device for different thickness and quality paper, which comprises the following parts: paper twisting mechanism, paper twisting pressure adjusting mechanism, overlapped-paper controlling mechanism and handy paper giving adjusting mechanism, wherein each part correlates, which connects chassis of device through rack or stand.


Complementary/alternative medical (CAM) providers continue to have a strong presence in the health care of United States citizens. The osteopathic physician may be in the position of having to interpret unfamiliar interventions and unfamiliar terminology as applied to her patient, and runs the risk of being seen as adversarial if she shows resistance or confusion in the presence of CAM influences. This article will describe several common forms of complementary/alternative health interventions, discuss related scientific evidence, if any, and provide information which may be helpful to physicians and patients when considering or integrating different health care paradigms. © 2009 Published by Elsevier Inc.


Hypothetical models have been proposed in which explicit collapse mechanisms prevent the superposition principle from holding at large scales. In particular, the model introduced by Ellis et al. [J. Ellis et al., Phys. Lett. B 221, 113 (1989)] suggests that quantum gravity might be responsible for the collapse of the wave function of massive objects in spatial superpositions. We consider here a recent experiment reporting on interferometry with atoms delocalized over half a meter for a time scale of 1 s [T. Kovachy et al., Nature (London) 528, 530 (2015)] and show that the corresponding data strongly bound quantum-gravity-induced decoherence and rule it out in the parameter regime considered originally.


HAUSAT-2 is nano satellite with 25kg mass being developed by Space System Research Lab. in Hnakuk Aviation University. This paper addresses HAUSAT-2 small satellite thermal analyses and its verification at satellite system, electronic box, and PCB levels. Thermal model which is used for system-level and box-level thermal analyses was verified and corrected through thermal vacuum/balance test. The new board-level thermal analysis methodology, modelling high-power dissipating EEE parts directly, was proposed. The proposed methodology has been verified with test results.


On the view of cleaner production,the full process of one enterprise is systematically assessed in the aspects of raw material, resources consumption,pollutant discharge. Then,the level of cleaner production of the enterprise is quantitatively analyzed in the papermaking trade.


Introduction Processing fluids have been recently adopted by the U.S. swine industry as a breeding herd PRRS monitoring tool due to their increased representativeness of animals within the herd. Here, we use the Morrison Swine Health Monitoring Project (MSHMP) database, representative of ~50% of the U.S. swine breeding herd, to describe processing fluids submissions for PRRS diagnosis and their relation to PRRS prevalence and time to stability over time between 2009 and 2020. Methods An ecological time series Poisson regression modeling the number of status 1 farms and weekly percentage of processing fluids submissions for PRRS diagnosis was done. Time to stability was calculated for sites that detected a PRRS outbreak within the study period and modeled through a proportional hazards mixed effect survival model using production system as a random-effect factor and epiweek as a panel variable. Results Processing fluids diagnosis submissions increased starting in 2017. The difference between each year's highest and lowest weekly prevalence averaged 10.9% between 2009 and 2017, whereas it averaged 5.0% in 2018–2020 period. Each year's lowest weekly prevalence ranged from 11.3 to 19.5% in 2009–2017 and from 22.4 to 29.2% in 2018–2020. We also detected an increasing proportion of breeding sites that did not reach stability within 1 year of reporting an outbreak (chi-square for trend p < 0.0001). The total time to stability was not associated with the region of the country in which the site was located, the site's air filtration status, its PRRS status before the outbreak, or the different statuses a site achieved to be classified as stable, when accounting for the production system in the multivariate model. However, a higher proportion of system-wide processing fluids use was associated with increased time to stability. Discussion Altogether, the temporal concurrence of processing fluids used for PRRS virus monitoring suggests that the adoption of this sampling strategy may help explain the changes observed in PRRS status 1 prevalence since 2018, although further studies are still needed.


The tragic consequences for the fetuses of pregnant women using the sedative thalidomide destroyed the theory that the placenta was a type of barrier protecting the fetus from the effects of maternal pharmacology. It now is known that virtually all drugs and chemical compounds cross the placenta. Because such compounds have to cross several lipoprotein barriers in vascular walls to travel from the maternal to fetal circulation, certain physicochemical characteristics of drugs and chemicals favor transport to the fetus: low molecular weight, lipid solubility, and nonionization at a pH of 7.4. Most drugs in current use (prescription and over-the-counter) cross the placenta. Most environmental toxins also cross the placenta and present a special problem; they are very lipid-soluble and may be stored in the woman's body fat, even from childhood until pregnancy occurs. With pregnancy may come mobilization and passage to the fetus. Details of when compounds are transferred across the placenta in pregnancy in humans are not available. Because we are unable to obtain more than the single simultaneous maternal and fetal samples available from the cord blood at delivery, our knowledge of maternal-fetal partitioning and pharmacokinetics remains fragmentary.
 Drug exposure can occur at any time from conception through labor and delivery.


Modern business processes are embedded in a complex environment and, thus, subjected to continuous changes. While current approaches focus on the control flow only, additional perspectives, such as time, are neglected. In this paper, we investigate a more general concept drift detection framework that is based on the Earth Mover's Distance. Our approach is flexible in terms of incorporating additional perspectives thanks to the capability of defining custom feature representations, as well as expressive feature similarity measures. We demonstrate the former by incorporating the time perspective using both a time-binning-based trace descriptor and a suitable similarity measure that considers time and control flow. We evaluate the resulting sliding window detector on different types of control-flow and time drifts, and holistic drifts involving multiple perspectives.


Time-resolved spectroscopic observations with the shock tube are described. Emission spectra are recorded for the high-temperature gas behind the shock reflected from the closed end of the tube. Simultaneous observations are made of the hydrodynamic variables. The state of the emitting gas is predicted by hydrodynamic theory and correlated with the observed spectrum. Deviations from ideal theory caused by viscosity and heat conduction are recognized, and their influence upon pressure and temperature is appraised by direct measurement.


A crucial part of a typical pattern recognition system is the extraction of the appropriate information that uniquely describes the patterns under processing. This information has the form of vectors and their contents are called features, which are constructed by specific extraction methods (Feature Extraction Methods FEMs). The length of the extracted feature vectors may take high dimension by incorporating many features for each pattern, although this huge information may be redundant and in a lot of cases this extra information corrupts the separability of the patterns under recognition. Therefore the need of an additional pre-processing method that reduces the feature vectors' dimension, by selecting the most appropriate features, subject to some performance indices (class separability, high classification error etc.) is necessary. This procedure is called dimensionality reduction or feature subset selection and has attracted the attention of the scientific community for the last thirty years (Molina et al., 2002). This chapter is focused on the usage of evolutionary methods in selecting the appropriate feature subset from a pool of features, in a way the resulted subset increases the recognition rates in several benchmark pattern recognition problems. A simple genetic algorithm is used to examine the usefulness of a predefined feature set of some benchmark problems from the literature and some useful conclusions about the ability of these features to recognize the patterns are drawn. Moreover, the dependency of the resulted feature subsets, as far as their classification abilities are concerned, on the form of the fitness function used to measure the appropriateness of the candidate solutions, constructed by the genetic algorithm, is studied in this chapter. Three fitness functions with different properties are examined and their performance is compared to each other, for a set of pattern recognition problems.


In order to optimize the hot stamping process of an A-pillar and speed up getting the product to the market, we separately simulate forming and heat transfer to get a better tooling design. In the analysis of forming, the thinning rate is under 30%, we judge that there is no crack issue. In the analysis of heat transfer, the cooling curve is out of bainite and ferrite in CCT diagram, so the cooling design can meet the requirements of quenching. Finally, we bring simulation to tooling and test variables to get a better process parameter.


Abstract Melanoma brain metastases (MBM) and leptomeningeal metastases (LMM) are two manifestations of melanoma dissemination to the CNS with vastly different survival outcomes. Analysis of single cell RNA-Seq data from 43 clinical specimens has uncovered a distinct, immune-suppressed T cell landscape in the LMM microenvironment that is distinct to those of the brain and skin metastases. An LMM patient with an extraordinarily long survival and documented response to therapy demonstrated an immune repertoire that was distinct from those of typical poor survivors and more similar to CSF from non-LMM donors. Analysis of serial specimens over the course of therapy demonstrated reductions in melanoma cells and macrophages, coupled with increased levels of T cells and dendritic cells in the CSF of the extraordinary responder, whereas poor survivors showed no improvement in T cell responses. In MBM patients, targeted therapy and immunotherapy was associated with increased immune infiltrate, with similar T cell transcriptional diversity noted between skin metastases and MBM - suggestive of immune cell trafficking into the brain. Treatment with targeted therapy was associated with an enrichment of CD8 T cells. Immunotherapy was associated with a more diverse lymphocyte landscape and higher numbers of antibody-producing cells. These findings were confirmed by multiplexed staining of patient specimens and using an immune-competent mouse model of MBM. Correlation analysis across the entire immune landscape identified the presence of a rare, novel population of dendritic cells (DC3s) to be correlated with increased overall survival, regardless of disease site/treatment. The presence of DC3s positively regulated the immune environment of both patient samples and preclinical melanoma models through modulation of activated T cells and MHC expression in the tumor. Our study provides the first comprehensive atlas of two distinct sites of melanoma CNS metastases and identifies rare populations of cells that underlie the biology of this devastating disease.


All possible graded extensions of the Poincare Lie algebra are constructed. Massless P2=O representations of these algebras are investigated and it is found that the usual conditions on massless particle helicity states necessarily imply constraints on the spinorial generators. It is shown that these constraints are not consistent with the graded Lie algebra, except for the case of conventional supersymmetry. It follows that massless representations of such algebras are forbidden.


A method for bonding an optical fiber (60) in a connector (1) optical fiber, said connector (1) optical fiber element (3) binding the fiber, a thermoformable material surrounding said element (3) comprising binding fiber and a body (2) of the connector surrounding said thermoformable material, the method comprising the steps of: - inserting the optical fiber (60) into the connector (1) optical fiber; - inserting the bare portion of the optical fiber (61) between a first portion of said member (31) connecting said fiber and thermoformable material, wherein said first portion of said member (31) connecting the fiber to contact with the bare portion of the optical fiber has a first area (CS1) of the cross section; - inserting the coated portion of the optical fiber (62) between a second portion of said member (32) connecting the fiber and thermoformable material, wherein said second portion of said member (32) connecting the fiber to contacting the coated portion of the optical fiber (62) has a second area (CS2) of less than said first area (CS1) of the cross section cross section; - activate the thermoformable material, thereby attaching the optical fiber (60) to the element (3) binding fiber; - attaching a bare portion of the optical fiber (61) to the element (3) binding and bonding a fiber coated portion of the optical fiber (62) to the element (3) binding the fiber.


Localization is a crucial requirement for mobile underwater systems. Real-time position information is needed for control and navigation of underwater vehicles, in early warning systems and for certain routing protocols. Past research has shown that the localization accuracy of networked underwater systems can be significantly improved using collaborative tracking techniques. More specifically the Maximum Likelihood (ML) position estimates of a mobile collective can be computed from measurements of relative positions and motion, albeit centrally and non-real time. While for a number of underwater applications non-real-time position estimates may suffice, in this paper we focus on the design of a collaborative tracking solution that operates in real-time, yet is scalable and energy-efficient. Using the ML solution as a baseline, we identify key factors that fundamentally limit the performance of real-time (centralized and distributed) solutions, quantifying their effects via simulations. In the remaining solution space, we propose a low overhead scheme for real-time and distributed tracking. The specific challenges that we address include determining what information should be shared between vehicles, how this information must be encoded to minimize the communication overhead and when should vehicles communicate with each other to achieve the best performance with the minimum energy consumption. Our proposed technique can strategically trade off localization accuracy and energy consumption, achieving more than 50% reduction in the communication overhead compared to any fixed scheme.


Small, shallow seepage lakes in northern Wisconsin that have both low winter oxygen concentrations and low pH possess depauperate fish assemblages containing primarily or exclusively central mudminnows, Umbra limi, and yellow perch, Percaflavescens. Six times during three years I determined the total densities of fish in five lakes by mark-recapture and catch-per-effort methods. The richness of the fish assemblages in these lakes varied from one to three species in a nested pattern. While seasonal variations in density occurred within and among lakes due to variations of growth, mortality, and recruitment, total densities overall were independent of species richness. This pattern, called complete density compensation, suggests that total densities are expressions of the lakes' similar abilities to support fish and that the species interact rather than being independent. An intense negative correlation between perch and mudminnow densities was found, suggesting a strong interspecific population dominance of perch over mudminnows. There was also indirect evidence that both com? petition (exploitation and interference) and predation by perch regulate mudminnow populations when the species co-occur. Because these assemblages were unpredictably variable in time and space, con- clusions from single censuses would have been unreliable. An exercise simulating single seasonal censuses from each richness class showed that less than one-half of such single censuses would have produced the pattern of complete compensation that was observed in the field study. In general, my results support the idea that the relative importance of the factors that determine community structure, or even the factors themselves, can differ not only from assemblage to assemblage at any one time, but even from season to season or year to year within a single assemblage.


When used in a corn grit-soybean bait at 1500-7500 ppm, AC-217,300 (2(1 H )-Pyrimidinone, tetrahydro-5,5-dimethyl-,[3-[ 4-(trifluoromethyl)phenyl]-1-[2-[ 4-(trifluoromethyl) phenyI]-2-propenylidene]hydrazone) provided control of Pheidole megacephala (F.) comparable to that with mirex bait at 3000 ppm when the baits were broadcast at 2.24 kg/ha in old and new pineapple plantings. Since the use of mirex is being discontinued because of environmental concerns, AC-217,300 has the potential to replace it in controlling ants, and thus wilt, in pineapple production.


Combining with the engineering project on Wuhu Road of Hefei that is intended to transform overhead grid underground,The article puts forward the design idea of the project of transforming facilities from overhead to underground and the questions related to the project.


The controversial picture of gay sexual promiscuity developed in Faggots, and the radical political positions portrayed in The Normal Heart during the AIDS epidemic have helped to build the reputation of Larry Kramer. However, in the same time, they seem to have made his discourse ineffective. Through the study of those two pieces, we are going to question the use of provocation in Larry Kramer's work and its effects.


ABSTRACT:Taking account of some narrative Shi'i commentaries as well as the principles of Islamic mysticism in the study of verses 42-43 of the Qur'anic chapter Sūrat al-Qalam, the present article deals with four propounded questions about the quality and conditions of a promised prostration on Doomsday, mentioned in verse 68:42. Applying the traditions mentioned in the statement, 'The day that the shin shall be laid bare and they shall be summoned to prostrate themselves' in the verse, as well as the transmutation ḥadīth (ḥadīth-i taḥawwul), we show that the two doctrines of Shi'ism and mysticism agree in associating the expression 'laying the shin bare' (kashf 'an sāq) with a divine theophany in the form of the Perfect Man. At the end of this paper, amalgamating the teachings of the two doctrines, we have concluded that the promised prostration on Doomsday is similar in cause and purpose to the angels' prostration before Adam.


A ball milling experiment was carried out with a powder premix of Bi and Sb to investigate the mechanical alloying effect on the thermoelectric properties of Bi-Sb thermoelectric semiconductor. The milling process and phase formation were monitored by X-ray diffraction analysis (XRD), SEM and EDX of the milled powders. The milled powders were sintered by hot-pressing. The microstructure of the sintered compacts was observed by TEM, and the electrical properties of compacts were measured by Van der Pauw method at room temperature and 77K. The X-ray diffraction analysis showed that the Bi92.5Sb7.5 solid solution was formed after 16 hours milling. The sintered compacts have a ultra-fine microstructure with an average grain size of less then 1 ƒÊm, and the grain size decreased with increase in milling time . The electrical properties of sintered compacts varied with milling time. The electrical resistivity slightly decreased with increase in milling time, which considered to be due to decreasing of carrier density and increasing of carrier mobility with milling time.


Rehabilitation of edentulous patient is done by dentist with the fabrication of complete denture. It is commonly observed that mandibular dentures are not satisfactory when compared to maxillary denture due to centrifugal resorption of mandible. Thus rehabilitation of atrophied edentulous mandible by using implant to support and retain the prosthesis is an acceptable treatment option. It adds to the denture stability, increase masticatory efficiency and comfort of the patient. The present case report discuss about a patient with prosthodontics rehabilitation consisting of single implant supported overdenture.


Since the output of treated water from the public treatment system until the moment of consumption, several factors may contaminate the product, such as transport, storage and handling. The lacking knowledge of population, or even wrong about the proper way of cleaning and maintenance from the reservoirs and residential water filters and the prolonged use of candles and taps from the filters can lead to drinking water contamination, affecting the life quality.


ASSA develops locks and integrated security systems for doors. ASSA is Sweden's leadingsupplier of locks and security systems. ASSA AB worked during the master thesis withimplementing a common deve ...


Objective To investigate the frequencies of chromosome 1p/19q co-deletion and its correlation with p53,phosphatase and tensin homolog deleted on chromosome ten (PTEN) and O6-methylguanine DNA methyltransferase (MGMT) protein expression in oligodendroglial tumors.Methods Samples of 68 oligodendroglial tumors (42 oligodendrogliomas and 26 anaplastic oligodendrogliomas) were collected.The 1p/19q status was detected by Fluorescence in Situ Hybridization (FISH) and the expression levels of p53,PTEN and MGMT protein were estimated semi-quantitatively by immunohistochemistry,then the correlations with I p/19q co-deletion were analyzed by t-test.Results The frequencies of 1p deletion,19q deletion,and 1p/19q co-deletion were 67.65% (46/68),61.76% (42/68) and 57.35% (39/68)respectively in 68 oligodendroglial tumor samples.There was no obvious difference of 1 p/19q co-deletion between low-grade oligedendroglioma and anaplastic oligodendroglioma ( P > 0.05 ).The frequency of 1p/19q co-deletion in frontal lobe (76.67%,23/30) was higher than that in temporal (45.00%,9/20) and the other lobes (38.89%,7/18) (P <0.05).There was no significant correlation between 1p/19q co-deletion,age and gender (P > 0.05 ). p53 and MGMT protein expression were positively correlated with tumor grade,but PTEN protein expression negatively correlated with tumor grade in oligodendroglial tumors (P < 0.05 ).Furthermore,there was a significant association between 1 p/19q co-deletion and low p53 and MGMT protein expression (P < 0.05 ),but there was no significant correlation with PTEN protein expression in oligodendroglial tumors (P > 0.05).Conclusion The combined deletion of chromosome 1 p/19q negatively correlates with the expression of p53 and MGMT protein in oligodendroglial tumors,which may be valuable in the diagnosis,treatment and prognostic prediction for oligodendroglial tumors.

Key words:
Oligodendroglial tumors; 1p/19q co-deletion; Fluorescence in situ hybridization; p53 protein; Phosphatase and tensin homolog deleted on chromosome ten; O6-methylguanine DNA methyltransferase


We have developed techniques which contribute to efficient algorithms for certain geometric optimization problems involving simple polygons: computing minimum separators, maximum inscribed triangles, a minimum circumscribed concave quadrilateral, or a maximum contained triangle. The structure for our algorithms is as follows: a) decompose the initial problem into a low-degree polynomial number of easy optimization problems; b) solve each individual subproblem in constant time using the methods of cealcuIns, standard methods of numerical analysis, or linear programming. The decomposition step uses shorteat path trees inside simple polygons (Guibas et. al.~ 1987) and, in the case of inscribed triangles, produces a new class of polygons, the fan-shaped polygon. By extending the shortest-path algorithm to splinegons, we also generate splinegon-versions of the algorithms for some of the optimization problems. The problems we discuss fall into four subgroups: Separa tors : If two points z and y lie on the boundary of simple polygon P and define a directed line segment zy C_ P that separates P into two sets PL and Pa, then zy is called a separator.


Guillain–Barré syndrome (GBS) is characterized by acute immune‐mediated peripheral neuropathy, which may result in rapidly progressive paralysis and fatal respiratory failure. As the underlying pathological mechanisms of GBS are unclear, we surveyed the transcriptome of rats with experimental autoimmune neuritis (EAN), a model of GBS. Briefly, sciatic nerves on both sides were collected from 8–10‐week‐old Lewis rats during early (10 days post‐induction), peak (19 days) and late neuritis (30 days). Total RNA was sequenced to identify differentially expressed genes. Compared to control rats without induced neuritis, 33 genes were differentially expressed in the early phase (14 up‐regulated and 19 down‐regulated), with an adjusted P‐value < 0·05 and |log2 fold‐change| >1, as were 137 genes in the peak phase (126 up‐regulated and 11 down‐regulated) and 60 genes in the late phase (58 up‐regulated and two down‐regulated). Eleven of these genes were common to all stages, suggesting their crucial roles throughout the disease course. Analysis of protein–protein interactions revealed Fos, Ccl2, Itgax and C3 as node genes at different stages. Functional analysis of differentially expressed genes identified biological processes and pathways that are activated as neuritis progresses. This is the first genomewide gene expression study of peripheral nerves in experimental autoimmune neuritis model. Dynamic gene expression and significantly altered biological functions were detected in different phases of the disease, increasing our understanding of the molecular mechanisms underlying EAN and highlighting potential targets for its diagnosis and treatment.


In this paper, we introduce how to use OpenGL to draw human face with high realism. We concentrate on the introduction of OpenGL programming experiences on Windows95 and the application of transformation, lighting, shading, texture mapping in OpenGL.


Few studies have been published about handling intercultural service-encounters. The limited prior publications have focused on satisfaction and dissatisfaction and have neglected the concept of inclusivity. This study reveals the sources of discriminatory services to customers who have limited English proficiency, focusing on those with limited English proficiency and presents components that can facilitate culturally inclusive service-encounters. A combination of lacking intercultural service policies and of language barriers lead to vulnerability amongst customers when receiving service. This study has determined that the necessary components for culturally inclusive service-encounters are: a) training and granting accessibility at the organizational level and b) patience and creating needs at the individual level. From the perspective of frontline employees, culturally inclusive service encounters require integration at both organizational and individual levels. Hospitality and tourism organizations are encouraged to train frontline employees on cultural differences and to embrace technologies that enable a realization of service value amongst customers with limited English proficiency.


Abstract The European dependencies for raw materials supply from foreign countries have been unquestionably shown by COVID‐19 outbreak and have become particular evident from the slow response to the need for high quality personal protective equipment (PPEs). Among all medical devices, surgical face masks have earned themselves a primary role for the containment of the epidemic. In this context, our work aims at improving the barrier effect of surgical mask by depositing on their external surface a mixture of bioactive compounds, mainly polyphenols, extracted from agronomical sources. The main objective is the integration of the biorefining of agri‐food solid wastes with the potential virucidal properties of the polyphenolic extracts for the treatment of PPEs.


Objective To investigate the clinical significance of preoperative colonoscopy for patients with benign anal diseases,and to compare the success rates of examination done by sedated colonoscopy and conventional colonoscopy.Methods The clinical data of 333 patients with benign anal disease who received preoperative colonoscopy at the Six Affiliated Hospital of Sun Yat-Sen University from April 2010 to March 2011 were retrospectively analyzed.All the patients were divided into the lesion group (120 patients) and normal group (213 patients)according to the results of colonoscopy.The measurement data and count data were analyzed using the t test and chi-square test,respectively.Results The age of patients in the lesion group was (48 ± 14) years,which was significantly older than (42 ± 14) years (t =3.75,P < 0.05).The constituent ratio of patients older than 40 years in the lesion group was 72.50% (87/120),which was significantly higher than 39.44% (84/213) in the normal group (x2=33.59,P <0.05).The proportions of male and female patients were 71.67% (86/120) and 28.33% (34/120) in the lesion group,and 62.44% (133/213) and 37.56% (80/213) in the normal group,with no significant difference between the 2 groups (x2 =2.90,P > 0.05).The benign anal diseases in the lesion group included polyp (80 cases),enteritis (30 cases),malignant tumor (7 cases),infflammatory bowel disease (7 cases),diverticulum (5 cases) and ulcer (1 case).The application rates of sedated colonoscopy in the lesion group and the normal goup were 51.67% (62/120) and 54.93% (117/213),respectively,with no significant difference between the 2 groups (x2=0.33,P >0.05).The success rate of terminal ileum intubation was 99.44% (178/179) in patients who received sedated colonoscopy,which was significantly higher than 95.45% (147/154) of patients who received conventional colonoscopy (x2 =5.61,P < 0.05).Conclusion Patients with benign anal disease might complicated with colorectal lesions,and sedated colonoscopy is recommended for preoperative diagnosis,especially for patients who are older than 40 years.

Key words:
Benign anal diseases ;  Colonic diseases ;  Rectal diseases ;  Colonoscopy ;  Diagnosis


When designing products with a shorter lifespan, such as packaging and graphic products, sustainability and circular economy are particularly important. The use of an alternative fiber source for papermaking, such as collected biomass from invasive alien plant species (IAPS), is a good example of sustainable natural resource management, where IAPS are seen as a potential source of various new products. The aim of the present study was to analyze the printability of paper made from the IAPS Goldenrod. CMYK prints were made using inkjet digital technology, and their print quality was determined. IAPS Goldenrod paper, with its natural brownish color, low gloss, high voluminosity, high surface roughness and porosity, shows inferior print quality compared to recycled office paper. In order to improve the printability of this paper, surface coating using three different wet film depositions was applied. The results indicate that the smallest coat weight used suppresses the color and inferior properties of IAPS Goldenrod paper efficiently, resulting in similar printability for both the analyzed papers. Only a small difference in print quality between coated IAPS Goldenrod and recycled paper was determined, suggesting that low-value, non-demanding graphic products and packaging could be made from the coated IAPS Goldenrod paper.


Studies investigating the associations of oral function and dysphagia with frailty and sarcopenia in community-dwelling older adults are increasing; however, they have not been systematically summarized. We conducted a systematic review to investigate these associations. We searched electronic databases and synthesized relevant data using conventional (frequentist-style) and Bayesian meta-analyses. Twenty-four studies were found to be eligible for our review, including 20 cross-sectional and four prospective cohort studies. Older adults with frailty or sarcopenia had lower tongue pressure, according to the results of conventional meta-analysis (mean difference [95% confidence interval or credible interval]: −6.80 kPa [−10.22 to −3.38] for frailty and −5.40 kPa [−6.62 to −4.17] for sarcopenia) and Bayesian meta-analysis (−6.90 kPa [−9.0 to −4.8] for frailty, −5.35 kPa [−6.78 to −3.89] for sarcopenia). People with frailty had a higher odds ratio (OR) for dysphagia according to the results of conventional meta-analysis (3.99 [2.17 to 7.32]) and Bayesian meta-analysis (1.38 [0.77 to 1.98]). However, the results were inconclusive for people with sarcopenia. A prospective association could not be determined because of the lack of information and the limited number of studies. Decreased oral function and dysphagia can be important characteristics of frailty and sarcopenia in community-dwelling older adults.


It considers the way of reducing aerodynamic drag of aircraft, connected with injection of supersonic gas stream from the forebody in approach flow. The accepted assumptions and restrictions are designated. The main results of research are presented.


L ifestyle factors can increase one's wellness or overall health for patients with multiple sclerosis (MS). This independent editorial clarifies the supporting literature behind the topics of discussion in a series of accompanying Bayer-supported videos filmed in partnership with the Multiple Sclerosis Association of America (MSAA).


The social movements arising from the social discontent comes to the forefront among the subjects that have begun to be studied after the 1960s within the sociology discipline. The explanation for the reasons of the social discontent which causes the emergence of the social movements may change according to the sociology schools. While the matters canalizing the society to step into reaction were assessed, the threat perception fed by the emotions which lead the actors to act was overlooked and thus this situation brought about mistakes in the examination of the movements. It is necessary to question the approaches on social movements in terms of the threat perception. This approach will bring the importance and necessity of the role of the emotions in human behavior to the attention of the researchers, as well.


Volatile flavor compounds are often retained in the dried carbohydrates in quantities greaterthan expected on the basis of vapor pressure characteristics. In an effort to elucidate the mechanism of this phenomena, the retention of volatile compounds in the model system was studied. The systems consisted of quartic mixture of water, organic volatile, glycerol and carbohydrate. The volatile content after freeze-drying was measured gas-chromatographically by extracting the dried material with 0.5ml of absolute methanol and injecting a 1.0μl sample.The retention of volatiles was influenced by a number of factors, including the relative volatility of each volatile compound and its diffusion coefficient. Sucrose or maltose solution retained larger quantities of volatiles than the solution of polysaccharide. The volatiles retained were; 26-45% of ethyl-n-butyrate and 65-87% of alcohols in the quartic mixture. The observed volatile retentions indicated that the formations of micellar colloid and microregion for entrapping volatiles are much more important than the equilibrium of gas-liquid or diffusion consideration of the volatile.


The continuous demand in electric power system network has caused the system to be heavily loaded leading to voltage instability. However, Flexible Alternating Current Transmission System (FACTS) devices provide the necessary features to avoid technical problems in the power systems. They also increase the transmission line efficiency. Among the FACTS family is Static Synchronous Compensator (STATCOM). The STATCOM (Static Synchronous Compensator) is the shunt connected FACTS devices which are connected to line via voltage source converter. Use of FACTS device is a best solution to mitigate the problem of reactive power compensation without construction of new transmission lines. It injects the compensating current in phase quadrature with line voltage, it can emulate as inductive or capacitive reactance so as to produce capacitive power for the AC grid or draws inductive power from the ac grid to control power flow in the line. KeywordsFACTS, STATCOM, Controller design, PI controller


The ferroelectric SBT films were deposited on Pt/Ti/SiO₂/Si substrates by liquid injection metalorganic chemical vapor deposition (MOCVD) with single-mixture solution of Sr[Ta(OEt) 5 (dmae)]₂ and Bi(C 6 H 5 )₃. The Sr/Ta and Bi/Ta ratio in SBT films depended on deposition temperature and mol ratio of precursor in the single-mixture solution. At the substrate temperature of 400℃, Sr/Ta and Bi/Ta ratio were close to 0.4 and 1 at precursor mol ratio of 0.5~1.0, respectively. As-deposited film was amorphous. However, after annealing at 750℃ for 30 min in oxygen atmosphere, the diffraction patterns indicated polycrystalline SBT phase. The remanent polarization (Pr) and coercive field (Ec) of SBT film annealed at 750℃ were 4.7 μC/㎠ and 115.7 kV/cm at an applied voltage of 5 V, respectively. The SBT films annealed at 750℃ showed practically no polarization fatigue up to 10 10 switching cycles.


Little work has been done on comparing the performance of statistical model-based approaches and nonrigid registration algorithms. This paper deals with the qualitative and quantitative comparison of active appearance models (AAMs) and a nonrigid registration algorithm based on free-form deformations (FFDs). AAMs are known to be much faster than nonrigid registration algorithms. On the other hand nonrigid registration algorithms are independent of a training set as required to build an AAM. To obtain a further comparison of the two methods, they are both applied to automatically register multi-slice myocardial perfusion images. The images are acquired by magnetic resonance imaging, from infarct patients. A registration of these sequences is crucial for clinical practice, which currently is subjected to manual labor. In the paper, the pros and cons of the two registration approaches are discussed and qualitative and quantitative comparisons are provided. The quantitative comparison is obtained by an analysis of variance of landmark errors, i.e. point to point and point to curve errors. Even though the FFD-based approach does not include a training phase it gave similar accuracy as the AAMs in terms of point to point errors. For the point to curve errors the AAMs provided higher accuracy. In both cases AAMs gave higher precision due to the training procedure.


The utility model discloses a self-service electronic product contracting and card-sending integrated machine which can carry out multiple automatic identity recognitions on people who activate cards, and achieves fast electronic product choosing, contracting and card sending. The machine comprises a machine body, an industrial control computer (IPC) arranged in the machine body, an identification card reader, a card sending machine, a camera, an image recognizer, a fingerprint scanning device, a touch screen displayer, an online bank secret key printer, a receipt printer, a protocol and customer confirmation printer, a credit card reader, a universal serial bus (USB) port and a metal keyboard, wherein the identification card reader, the card sending machine, the camera, the image recognizer, the fingerprint scanning device, the touch screen displayer, the online bank secret key printer, the receipt printer, the protocol and customer confirmation printer, the credit card reader, the USB port and the metal keyboard are connected with the IPC. The identification card reader, the camera, the fingerprint scanning device, the touch screen displayer, the USB port and the metal keyboard are arranged on a panel of the machine body, the card sending machine and the credit card reader are disposed in the machine body, a card out-in opening is formed in the panel of the machine body, and an exit of the online bank secret key printer, an exit of the receipt printer, an exist of the protocol and customer confirmation printer are located in the panel. The IPC is further connected with a computer network of a bank.


The offshore structural design practice in Malaysia only focus more on wind and wave effects analysis rather than seismic effect. At the east of Malaysia, the Philippine plate moves westward with an estimate velocity of 80mm/year and cause micro faults in Sabah. Thus, this thesis develops the earthquake ground motion due to Philippine earthquake for assessment of offshore platform in Malaysia. Besides, the adequacy of existing design of offshore platform in Malaysia is determined when subjected to earthquake loading. The analysis of behavior of the offshore platform structures of 3-legged fixed offshore structures under the earthquake effect is obtained to develop the earthquake design criteria for the offshore structures that are located in Malaysia region. The assessment of fixed offshore structure also covers the static and dynamic for the earthquake analysis by using the code of practice of "Recommended Practice for Planning, Designing and Constructing Fixed Offshore Platforms (API RP-2A, 2000). As for designing the offshore platform, this analysis is considering the dead load, live load, environmental loads (wind, wave and current load) and earthquake load such that free vibration, time history and response spectrum. The SAP 2000 computer program has been used to check the steel structure based on Eurocode 3, 2005. The most critical member of jacket offshore platform for the analysis of the various load also determined by compared the element capacity with manual calculation. However, there are assumption has been made such that the structure is fixed to the ground and the geometry, material properties and section properties of the structure are represent almost the same from the actual structure


ABSTRACT Doctoral programmes in which candidates research their own practice can be characterised as having transdisciplinary (TD) qualities. While most of the emphasis in the literature and in policy on TD is on research in teams, we argue for an expansion of the scope in the conception and understanding of TD research to include the way it can be articulated and assessed in practice-led and practice-based doctorates. In this sense, it is worth exploring instances of doctoral programmes that potentially allow doctoral researchers to undertake projects that have TD qualities. In these doctoral projects, researchers draw from a variety of perspectives, for example from their work practices, the theorisation of those practices, experiential learning, multiple disciplinary knowledge and approaches as well as communications and networking with appropriate stakeholders. Drawing from previous scholarship of TD in other fields we analyse and evaluate the TD qualities of a particular doctoral programme. This analysis reveals a set of qualities recognised by the literature as TD and relevant to doctoral researchers: Researching collaboratively with stakeholders; Diversity of disciplinary expertise and assessment criteria; Integration of different methodologies; Situating the research in multiple contexts; Impact on the 'situation' through novel procedures or products; Ethics and the importance of trust; Reflection/reflexivity. The paper posits a convergence between practice doctorates and TD research and demonstrates how TD qualities help doctoral candidates to situate their research at the interface between academia and their professional work and develop projects that have creative and beneficial relevance for practice.


This short exhibition catalogue documents the work of eight contemporary American and European artists. Includes brief comments by the artists. Biographical notes. Circa 100 bibl. ref.


The low bioavailability of hydrophobic organic compounds (HOCs) is one of the key sources of uncertainty in the implementation of in situ bioremediation. Bioavailability of HOCs in the subsurface is affected by sorption/desorption processes in two important ways. First, sorption causes high organic concentrations in microporous regions and impermeable zones to which bacterial access is obstructed. Second, because desorption and immobile zone diffusion must occur before biodegradation can proceed, the overall rate of bioremediation can be limited or even controlled by these mass transfer processes, not by the activity of the degrading microorganisms. Rate models that couple sorption/desorption—related mass transfer processes and biodegradation have been successfully applied to laboratory results and are beginning to offer some insight into the problem. Specifically, the influence of sorption on biodegradation is quantified here by defining a bioavailability factor, Bf. However, many questions remain and predictive modeling is elusive, especially in the context of complicated heterogeneous natural systems. Challenges facing environmental engineers are to develop a better understanding of these processes at both laboratory and field scales and ultimately to use such understanding toward the development of more effective and economical remediation technologies.


To explore the therapeutic effect of sacrococcygeal bone marrow edema after sacrococcygeal pilonidal sinus operation. After operation, patient was given antibiotics, anti anaerobic agents and surgical dressing. After 24 days, the sacrococcygeal wound healed. After 42 days, the sacrococcygeal bone marrow edema evidently subsided. Following up 1 year, no discomfort, no bone marrow edema was found.

Key words:
Pilonidal Sinus; Sacrococcyx; Bone marrow edema


Single-crystalline wurtzite CdS nanowires underwent gas-phase substitution to form unique superlattice cubic Cu1.8S (digenite) and hexagonal Cu2S (chalcocite) structures, using thermal evaporation of CuCl2 at 500∼600 °C. The Cu1.8S nanowires consisted of superlattices along the 〈111〉 direction, with controlled growth direction ([110], [211], [100], [111]) and superlattice periods of 1.6 and 1.9 nm. As the temperature decreased, the growth direction evolved from [100] to the higher surface-energy [110] or [211] directions, with longer superlattice periods. The Cu2S nanowires also exhibited a superlattice along the [0001] growth direction, with a periodicity of 2.7 nm and could be irreversibly converted into superlattice Cu1.8S by electron-beam irradiation.


Measurements are reported of the rates of proton transfer from ring-substituted ethyl α-benzylacetoacetates, 3-benzylpentane-2,4-diones, and benzylmalononitriles to a series of carboxylate ions. For the first two series the Bronsted exponents for substitution in the carbon acid are considerably greater than those for substitution in the carboxylate ion, and this behaviour is compared with the more extreme differences previously reported for reactions of the nitro-alkanes. For the benzylmalononitriles both exponents are equal to unity. Velocity constants are also given for the reactions of 3-benzylpentane-2,4-diones with water and with pyridine, and of benzylmalononitriles with water.


Objective The platelet rich plasma combined with deproteined bovine cancellous bone was applied in the posterolateral fusion of lumbar and the initial stage effect was evaluated. Methods Froty patients were treated with lumbar fusion which were randomly assigned into 2 groups: experimental group and control group. There were 20 cases in each group. Platelet rich plasma combined with deproteined bovine cancellous bone was transplanted in the experimental group and deproteined bovine cancellous bone was applied in the control group. The effect of lumbar fusion was evaluated by bone fusion, disappearance of bone transplant and alteration of disc height and so on. Results Rejection reaction was not found on 2 groups. There was no obvious difference between 2 groups from 1 to 3 months after operation. And there was no obvious difference between 2 groups in alteration of disc height and intervertebral angle 6 months after operation(P0.05). But the alteration of kyphosis angle in the experimental group was more distinct than which in the control group(P0.05). There was obvious difference between 2 groups in alteration of disc height, intervertebral angle and kyphosis angle 12 months post-operatively(P0.05). Conclusion The platelet rich plasma combined with deproteined bovine cancellous bone could enhance the bone healing obviously.


Objective: Based on our previous findings that DC‐SIGN‐expressing B cells could transmit HIV‐1 to T cells (PLoS Pathog. 2:e70, 2006), we determined the relative role of other B cell surface markers in this process.


The only FDA-approved oral immunotherapy for a food allergy provides protection against accidental exposure to peanuts. However, this therapy often causes discomfort or side effects and requires long-term commitment. Better preventive and therapeutic solutions are urgently needed. We have developed a technology for inverse vaccination using glyco-polymerized antigens to induce antigen-specific non-responsiveness. We have demonstrated that following subcutaneous (SC) administration, glyco-polymer conjugates traffic to draining lymph nodes (LNs) and are preferentially internalized by antigen presenting cells, educating the immune system to respond to these antigens in an innocuous way. Here, we tested SC administration of glyco-polymerized β-lactoglobulin (BLG) in a murine model of cow's milk allergy. Two doses of glyco-polymerized BLG given one week apart (prior to sensitization) prevented an allergic response to BLG upon intragastric challenge as measured by reductions in BLG-specific IgG, IgG1, and IgE production as well as BLG-specific type 2 T helper cell (Th2) responses in vitro. We further explored the therapeutic potential of glyco-polymerized BLG. Unlike unmodified BLG, two SC injections of glyco-polymerized BLG after sensitization did not cause anaphylactic reactions in allergic mice and inhibited cellular Th2 cytokines upon BLG restimulation. Since pre-existing humoral immunity inhibited the therapeutic effect of our glyco-polymerized BLG, we introduced a co-therapy (anti-CD20) to blunt the humoral response and observed ameliorated anaphylactic responses following glyco-polymerized BLG therapy. This platform may provide a potential T cell-modulating strategy to prevent and treat food allergies.
 This work was supported in part by seed funding from the Chicago Immunoengineering Innovation Center at the University of Chicago as well as the Food Allergy Fund.


drawing explicitly on the work of Gramsci and Mannheim (Chapter 8). There he sets the agenda for what is perhaps his most ambitious task yet ―'&dquo;... the complex realities explored if1 Gramsci's analyses of 'hegemony' and of 'organic' intellectuals&dquo; ~~.~21) that, from one of the more famous &dquo;scholarship boys&dquo; will indeed be worth waiting for. But in the meantime, Williams has offered us a very useful set of hypotheses and typologies, well suited to concrete practice.


In the 1950's and 1960's a strong dollar standard existed; under fixed exchange rates the monetary policies of most nations were governed by the stable monetary policy of the United States. In the 1970's, the dollar standard was reduced to a weak form where industrial (but not less-developed) countries float their exchange rates to secure more domestic monetary independence, but the financial processes underlying international trade itself remain dollar based. What are the elements of the weak dollar standard necessary for world trade to remain largely monetized and multilateral? How can nations avoid a relapse to the bilateralism and barter that characterized the 1930's? I shall consider first, necessary restraints on foreign exchange intervention and reserve holdings by central banks of industrial economies other than the United States; and second, the proper American monetary policy for reconciling the weakened international role of the dollar with domestic monetary stability.


The invention discloses a three-jaw fixing base. Multiple supporting bases are arranged at the bottom of the base, a fixing cap is arranged at the bottom of each supporting base, each supporting base is provided with a threaded rod, threads are arranged in the base, the threaded rods are matched with the internal threads, and the tops of the threaded rods are connected with a lifting plate; fixing claws are arranged on the base and connected with adjusting knobs, the adjusting knobs are connected with fixing parts, and the fixing parts are fixed to the base through first bolts and second bolts. The base is easy to use and install, convenient to disassemble, good in fixing effect and capable of fixing and supporting an optical instrument well.


There has been a great deal of interest in the use of direct sequence spread spectrum (DS-SS) in combination with multicarrier modulation (MCM). Although the proposed system implementations in the literature vary, all of these systems share the functionality of DS-SS, MCM, and some form of a branch combiner at the receiver. We investigate the performance of such a system transmitting through a Doppler spread channel. In Doppler spread fading, the proposed system performance exhibits an irreducible bit error probability (BEP) even for the single user case. Dramatic performance improvements can be realized with the use of an ideal maximal ratio combiner (MRC). A system utilizing an equal gain combiner (EGC) is analyzed. Finally, we compare the analytic results with the results from several computer simulations.


Abstract : New findings are presented providing physical insight on the effect of moisture and sea salt on high-frequency seismoacoustic waves in beach sand. Quantitative results reveal that the velocity of high-frequency compressional waves increases by about 8% as the water content is decreased by 18% from full saturation 1-3. This increase in velocity is in contrast with the Biot-Gassmann theory which predicts that the velocity of low-frequency compressional waves decreases by 85% as the water content is decreased by only 1% from saturation 4. Velocity plots as function of water saturation are compared for different sands and spherical glass beads. The effect of sea salt on grain to grain acoustic coupling is demonstrated. Salt crystallization and transport can lead to the &formation of hard sand/salt layers with a compressional velocity increasing from 200 m/s to 2887 m/s, and a shear velocity increasing from 10 m/s to 1885 m/s 3. A hypothesis is discussed with preliminary results on the potential existence of a suction-cup effect increasing the rigidity of unconsolidated compacted sediments, in the absence of roughness, due to the formation of cavitation microbubbles as the tensile strength of the thin capillary water film between compressed sand grains is exceeded 5.


l. R.W. Israel. Soil Stabilization and Cold Mix Recycling. Bomag, USA, 1982. 2. Materials for Stabilization. American Road and Transpo,rtation Builders Association, Washington, DC, Sept. 1976, 21 pp. 3. J.'A. Epps. State-of-the-Art Cold Recycling. TRB, Transportation Research Record 780, 1980. pp. 68-100. 4. Cold Recycling in a Centrcil Plant Takes Planning. Heavy and Highway Construction, July 1979, pp. 78+. 5. Standard Equipment Makes Old Road New. Heavy and Highway Construction, Feb. 1979, pp. 34-35. 6. J.F. Wood. Cold Recycling Equipment. Proc., Recycling Asphalt and Concrete Pavements, Univ. of Michigan, Ann Arbor, March 24-25, 1981, pp. 151-169. 7. Cold Recycling of Roads Paying Off in Texas. Civil Engineering, American Society of Civil Engineers, Nov. 1980, pp. 47-48. 8. H. Muncy. Recycling with Asphalt Emulsions. Rural and Urban Roads, March 1981, pp. 34+. 9. R.G. Maag. Cold Recycling of K-96 Scott County, Kansas. Proc., Asphalt Emulsion Manufacturers Association, Feb. 10-11, 1982. 10. R.G. Maag. Kansas Evaluates 1978-79 3R Experiments. Rural and Urban Roads, Nov. 1980, pp. 38+. 11. R. Watkins and w. Birt. What CALTRANS Learned 315


The purpose of this study was to describe findings and associations at the group level, and predictive accuracy at the individual level, for three measures of language obtained from a single prospective cohort of US children assessed at three ages during another investigation. Participants comprised all children (n = 414) who had a score at each of three ages (3, 4, and 6 years) on three language measures: Peabody Picture Vocabulary Test-Revised (PPVT); mean length of utterance in morphemes (MLU); and total percentage of phonemes correct (TOTPPC) in a nonword repetition task. At the group level, mean differences and correlations over ages were calculated. At the individual level, the extent to which low scores (1.5 SDs or more below the sample mean) at an earlier age increased the relative risk (R') of low scores at a later age was calculated. At the group level, scores on all measures increased significantly with age. Earlier and later scores on each measure were significantly correlated; r2 values were generally modest (12–59%). A low score at age 3 did not increase the risk of a low score age 4 or age 6 for any of the measures; a low PPVT score at age 4 significantly increased the risk (R' = 5.0) of a low PPVT score at age 6. For these generally healthy children and these language measures, predictive accuracy at the individual level was generally poor between the ages of 3, 4, and 6 years. Large, longitudinal studies are needed to identify and validate measures for use in identifying preschool children at risk for later language deficits.


A considerable enhancement of the yield and a reduction of the threshold of infrared multiphoton dissociation of SiH4 molecules is predicted theoretically and confirmed experimentally near the surface of a copper grating with a periodic relief. The effect is due to an increase in the local fields as a result of diffraction of bounded light beams by the rough surface under conditions of resonant excitation of surface electromagnetic waves.


Objective: Since the emergence of the COVID-19 pandemic at the end of 2019, the number of affected cases has not stopped rising. Similarly, the number of scientific publications and pre-prints has been increasing exponentially, with an effort to understand this disease more and find a proper solution. The purpose of this article is to review the current understanding of the novel coronavirus.

Background: The latest COVID-19 pandemic caused by the SARS-CoV-2 has spread globally ever since it emerged in Wuhan's city in China. This rapidly spreading disease has changed our lives in unimaginable ways, spreading fear and uncertainty due to the lack of knowledge and the flooding with new information, which lacks the scientific method and cannot be critically appraised. The purpose of this article is to gather some of the best knowledge that has been published so far in a unified narrative review, making it easy for the scientific community to review the most accurate and recent understandings about COVID-19.

Methods: We screened relevant articles using a specified number of keywords and specific databases, including PubMed and Embase. We selected peer-reviewed English published material related to the topic, except for a few pre-prints that we deemed necessary to include. We also screened the reference lists of these articles to find relevant publications with the same criteria.

Discussion: This narrative overview comprises several subsections that discuss the epidemiology, virology, pathogenesis, clinical manifestations, diagnostic methods, and management of the disease. We also presented a section on the implications of the disease in pregnancy. We wrapped up the review with a special division regarding the response to COVID-19,  which has been diverse in different countries.

Conclusion: COVID-19 has been a serious global health threat with a high transmission and case fatality rate, particularly in vulnerable populations. Epidemiologic models have so far guided the response, but they need to be interpreted carefully, with an understanding of their limitations. The disease's response has varied among different countries; with no current vaccine or standard treatment, the world stands in fear, maximizing preventive strategies to reduce the damages caused by this virus. This manuscript presents a summary of everything that is so far known about COVID-19 to make it easier for the medical community to overview the disease that has changed the world.


It has been experimentally established that an increase in the efficiency of cardiac glycosides can be achieved when they are combined with stimulators of protein synthesis and nucleic acids that can affect the processes of protein anabolism in the myocardium [3, 5, 6]. At the same time, stimulation of protein synthesis (proper anabolic effect) and blockade of protein breakdown (anti-catabolic effect) of anabolic steroids, apparently, can be enhanced by their combination with protein hydrolysates or mixtures of amino acids.


As an intermittent energy source, the injection of solar power into electricity grids requires irradiance forecasting in order to ensure grid stability. On time scales of more than six hours ahead, numerical weather prediction (NWP) is recognized as the most appropriate solution. However, the current representation of clouds in NWP models is not sufficiently precise for an accurate forecast of solar irradiance at ground level. Dynamical downscaling does not necessarily increase the quality of irradiance forecasts. Furthermore, incorrectly simulated cloud evolution is often the cause of inaccurate atmospheric analyses.
In non-interconnected tropical areas, the large amplitudes of solar irradiance variability provide abundant solar yield but present significant problems for grid safety. Irradiance forecasting is particularly important for solar power stakeholders in these regions where PV electricity penetration is increasing. At the same time, NWP is markedly more challenging in tropic areas than in mid-latitudes due to the special characteristics of tropical homogeneous convective air masses.
Numerous data assimilation methods and strategies have evolved and been applied to a large variety of global and regional NWP models in the recent decades. Assimilating data from geostationary meteorological satellites is an appropriate approach. Indeed, models converting radiances measured by satellites into cloud properties already exist. Moreover, data are available at high temporal frequencies, which enable a pertinent cloud
cover evolution modelling for solar energy forecasts. In this work, we present a survey of different approaches which aim at improving cloud cover forecasts using the assimilation of geostationary meteorological satellite data into regional NWP models.
Various approaches have been applied to a variety of models and satellites and in different regions of the world. Current methods focus on the assimilation of cloud-top information, derived from infrared channels. For example, those information have been directly assimilated by modifying the water vapour profile in the initial conditions of the WRF model in California using GOES satellite imagery. In Europe, the assimilation of cloud-top
height and relative humidity has been performed in an indirect approach using an ensemble Kalman filter. In this case Meteosat SEVIRI cloud information has been assimilated in the COSMO model.
Although such methods generally provide improved cloud cover forecasts in mid-latitudes, the major limitation is that only clear-sky or completely cloudy cases can be considered. Indeed, fractional clouds cause a measured signal mixing cold clouds and warmer Earth surface. If the model's initial state is directly forced by cloud properties observed by satellite, the changed model fields have to be smoothed in order to avoid numerical
instability.
Other crucial aspects which influence forecast quality in the case of satellite radiance assimilation are channel
selection, bias and error treatment.
The overall promising satellite data assimilation methods in regional NWP have not yet been explicitly applied and tested under tropical conditions. Therefore, a deeper understanding on the benefits of such methods is necessary to improve irradiance forecast schemes.


An input-parallel, output-series dc–dc Boost converter with a wide input voltage range is proposed in this paper. An interleaved structure is adopted in the input side of this converter to reduce input current ripple. Two capacitors are connected in series on the output side to achieve a high voltage gain. The operating principles and steady-state characteristics of the converter are presented and analyzed in this paper. A 400 V/1.6 kW prototype has been created which demonstrates that a wide range of voltage gain can be achieved by this converter and it is shown that the maximum efficiency of the converter is 96.62% and minimum efficiency is 94.14%. The experimental results validate the feasibility of the proposed topology and its suitability for fuel cell vehicles.


ICE/ced-3 related proteases (caspases) have been implicated in programmed cell death in a wide variety of cell types. However, their roles in radiation-induced cell death in cultures of mixed, neuronal and glial precursors cells are poorly understood. In order to further elucidate the molecular mechanisms underlying radiation induced death in this system; we have examined the ability of ionizing radiation to induce cell death and the caspase-3 activity. Survival decreased in a dose-dependent manner 24 h after a single 0,1 to 4 Gy dose of ionizing radiation. Irradiation resulted in a significant induction in caspase-3 activity, as measured by increased cleavage of colorimetric caspase substrates. Specific inhibitor of caspase-3, zDEVD-fmk, protected only partially from radiation induced cell death. These results demonstrate that cell death occurred despite of caspase-3 inhibition, and suggest that radio-induced cell death may occur by other mechanisms.


In rational drug therapy, the oncurrent administration of two or ore antimicrobial agents is often ssential and sometimes mandatory in rder to achieve the desired erapeutic aim to treat co-existing iseases. However, drug interaction ay have different effects on the host s well as the infecting organism (1) nd can decrease potency, increase dverse effect or toxicity (2). reatment of mixed infections, erapy of severe infections in which a pecific causative organism is known, nhancement of anti-bacterial activity the treatment of specific infections nd prevention of the emergence of


s of teachers and invited speakers............................................................5 About "Learning" in Artificial Intelligence. Daniel Apollon.....................................................7 Digital Games and Foreign Language Didactics. Myriam Coco...............................................8 Decoratives, controls and squiggles: Seeing the forest for the trees. Erica de Vries.................9 Back from Mars – a practical approach to game based learning. Peter Döppler....................10 Beyond Badges and Leaderboards! Concepts and Challenges of Gamification in Education. Helge Fischer..........................................................................................................................11 Differences matter. How to identify inclusive, open and participative practices of innovation. Thomas Köhler........................................................................................................................12 How to integrate educational and analytical perspectives on collaborative online learning: Reflection on 20 years of virtual collaborative learning (VCL) in Higher Education. Eric Schoop.............................................................................................................................13 Gamification Topic On Students' Final Task in UNY Postgraduate Year 2015-2020". M. Bruri Triyono .....................................................................................................................14 Abstracts of PhD Students and Post-Docs............................................................15s of PhD Students and Post-Docs............................................................15 Coaches' mentoring roles and students' self-efficacy beliefs. Dina Adinda ............................17 Deficient feedback engagement in E-learning reasons and measures. Mattis Altmann ..........19 Digitalization in the Bolivian schools. Silvia Blass ................................................................21 An Innovative Platform to Qualify Corporate Community Managers. Alexander Clauss......24 Characterising pervasive games as experiences: towards a design framework. Diane Dufort...........................................................................................................................27 Online learning in Covid-19: case of Cameroon. Steve Edgar Feze Feugang.........................29 Trump Card Played? Risks and Side Effects of Gamification. Matthias Heinz........................31 Immersive Technology for More Personalized, Dynamic and Effective Approach in Learning. Yuliana Irma............................................................................................................................33 The learning experience assessment of Serious Games. Ying-Dong Liu.................................35 Cooperation in the field of vocational education and training: research on cooperation between learning places in the area of hotel management in Indonesia. Rita Fransina Maruanaya......37


Spry rendering is a modular visualization environment (HVE) similar in many ways to AV$, IBM DX, and 5GI Explorer. It retains the main atu-active features such as modularity, extensibility and relative ease of use. Its distinguishing features are its execution flow and the finer granularity ol r visualization modules. In this paper we briefly describe the Spray rendering environment together with its mix-and-match capabilities and its collaborative visualization extensions. We then highlight its differences from other systems and list some of the advantages offered by spray rendering. Finally, we look at some of the open issues and challenges facing our system and MVEs in general.


Polarization dependence of the two-photon photoemission spectrum has been measured in a layer-type semiconductor ε-GaSe for nitrogen laser excitation. This is the first demonstration that the present technique provides the means for determining the absolute energy level with respect to vacuum and symmetry of the energy band. The result of our analysis is consistent with the band structure calculation of Schlüter et al.


The paper builds a discrete mathematic model for automatic drainage system and operates the sequential decision control to drainage system according to the optimality principle by dynamic programming.


The AM/FM radio adopting electronic tuning systems are increasing in number spreading from car radios to home stereos. The electronic tuning system electronically controls the DC tuning-voltage to the varactor diodes in the receiver circuits, instead of mechanically controlling the variable capacitor or a variable inductance coil, tuning the receiver to the desired channel. The electronic control system fits the demand toward smaller size and increasing functions of a radio, also cost reduction by LSI prompts the tendency to use the electronic tuning system in radios.


Objective To understand and grasp the bacteriostasis situations of Yankang tablet and its main raw material for staphylococcus aureus pneumonia and Cray Borrelia bacteria in vitro. Methods To observe effect of Yankang tablet and its raw materials honeysuckle against staphylococcus aureus and pneumonia Cray using immiscible bacteriostasis method,and to test the minimal concentration of honeysuckle against two kinds of bacteria with spectrophotometric method. Results The Yankang tablet and its raw materials honeysuckle,menthol have certain inhibitory action on pneumonia Cray Borrelia bacteria and staphylococcus aureus,menthol was strongest,honeysuckle was second;the minimal concentration of honeysuckle against staphylococcus aureus pneumonia and Cray Borrelia bacteria respectively were 7.2% and 5.4%. Conclusion The Yankang tablet and its main raw materials have different degrees of antibacterial activityin vitro.


On November 2006 Adrian Guissarri´s Library has reached the ISO 9001:2000 Standard Quality Accreditation. In 2009 the library achieved a new accreditation for ISO 9001:2008, to guarantee our System we designed our Quality Manual and the Procedures that allow us, day by day, the continuous improvement of our working environment. The key of the System is the Balanced Scorecard. This tool has indicators we use to monitor the library's normal functioning. The Balance scorecard allows us to give an effective and efficient service to our users. These indicators are based on the Strategic Map Model, built by Kaplan and Norton in four perspectives: finance, an intern proccess, a growing and educational and finally, a user's perspective


We present images taken using the Gemini South Adaptive Optics Imager (GSAOI) with the Gemini Multi-conjugate Adaptive Optics System (GeMS) in three 2 arcmin2 fields in the Spitzer Extragalactic Representative Volume Survey. These GeMS/GSAOI observations are among the first ≈0.″1 resolution data in the near-infrared spanning extragalactic fields exceeding 1.′5 in size. We use these data to estimate galaxy sizes, obtaining results similar to those from studies with the Hubble Space Telescope, though we find a higher fraction of compact star-forming galaxies at z > 2. To disentangle the star-forming galaxies from active galactic nuclei (AGNs), we use multiwavelength data from surveys in the optical and infrared, including far-infrared data from Herschel, as well as new radio continuum data from the Australia Telescope Compact Array and Very Large Array. We identify ultraluminous infrared galaxies (ULIRGs) at z ∼ 1–3, which consist of a combination of pure starburst galaxies and AGN/starburst composites. The ULIRGs show signs of recent merger activity, such as highly disturbed morphologies and include a rare candidate triple-AGN. We find that AGNs tend to reside in hosts with smaller scale sizes than purely star-forming galaxies of similar infrared luminosity. Our observations demonstrate the potential for MCAO to complement the deeper galaxy surveys to be made with the James Webb Space Telescope.


In the present paper, a transonic mixed-flow compressor that has relatively lower frontal area than that of centrifugal compressors is discussed, and aerodynamic design as well as performance prediction are performed. Main design constraints are compressor exit Mach number of 0.3 and flow angle of 30degrees at the design point, and maximum overall compressor diameter of 177mm, that is 7.0inch. The mass flow rate of design point and pressure ratio are 1.05kg/s and 5.2:1, respectively. The aerodynamic design results show that the transonic compressor designed with forward-swept inducer and curved diffuser can have the target performance with efficiency of 75% within the given constraints. And the compressor exit flow characteristics are discussed here.


236 237 238 239 Science Centre OOSH OOSH Garage Cottage 1 Cottage 2 OOSH Kitchen / Dining Hall / Student Accommodation Student Accommodation I Student Accommodation II B&G Stores / Student Rec Room Student Accommodation Heads Resisdence, Student Accommodation Student Accommodation III iC Central Australian Institute for Innovative Materials (AIIM) The Mike Codd Building Institute for Transnational & Maritime Security (ITAMS) iC Enterprise 1 Australian Institute for Innovative Materials Processsing & Devices (AIIM P& D) Electron Microscope Facility (EMF) The Sustainable Buildings Research Centre Illawarra Flame House iAccelerate