In 1959, the physicist Richard Feynman advised his colleagues that "there's plenty of room at the bottom." He envisioned a discipline devoted to manipulating smaller and smaller units of matter. "I am not afraid," he wrote, "to consider the final question as to whether, ultimately -- in the great future -- we can arrange the atoms the way we want, the way very atoms, all the way down." However, in early 1980's the doom and gloom of silicon MOS transistors was foreshadowed and scaling of the humble MOS transistors beyond 140 nm appeared as the impossible dream. Manipulation of material science, the emergence of low-K material and copper technology together with new techniques in lithography and processing have paved the way for revised predication that has foreshadowed the feature sizes in the order of 20 nm - 30 nm will occur somewhere between 2012 and 2016. Coupled with these developments, nanochemists have began to probe into matter and now Nanochemistry is beginning to shape the future of new materials and better understand the unique properties of assemblies of atoms and molecules on a scale that range between that of individual building blocks and the bulk material, thus confirming Feynman's vision. At this level quantum effects can be significant and innovative ways of carrying out chemical reactions become possible.


Due to the intensive development of renewable energy, producing electricity in an irregular and unpredictable way, storage looks set to play an increasingly important role in the energy system. There are only two systems currently used to store electricity on a large scale: pumped storage and compressed air energy storage (CAES), whose respective special geographical requirements mean it is hard to find the right place to implement them in practical terms. This paper takes a comparative look at 'geography-free' liquid air energy storage (LAES) vis-à-vis systems based on compressed air, including balance calculations for selected configurations. A comprehensive energy and exergy analysis was conducted together with a comparison of storage volumes for the systems under consideration.


The present study aims to detail the views and preferences about autism of Spanish-speaking professionals and students related to this condition. For this study, the method was exploratorydescriptive. In total, 816 participants, including teachers, psychologists, doctors, students and unemployed people, responded to an online questionnaire as an initial request of a MOOC course related to autism and inclusive education. Their answers were collected through four choicequestions based on the most controversial terminology related to autism (identity, person or diversity first, Asperger / autism distinction, descriptors). The results showed that, in general, the five groups opted for more inclusive terms, discarding the use of the term disability or weaknesses, and emphasizing the strengths of each individual (between a 75 – 83% of the participants). With regard to the active participants in their profession (teachers, psychologists and doctors), a clear preference for academic terms was denoted, such as Autism Spectrum Disorder (81% of the psychologists / educational psychologists, and 70% of the doctors and teachers). The differences between terms in Spanish compared to English are discussed in the use of person first or diversity first, as well as the importance of the context factor, and the use of the MOOC platform for the implication of the participants who usually choose this type of specific courses are emphasized. In conclusion, the use of inclusive language regarding autism by a Spanish-speaking community is highlighted.


Amid the growing prevailing globalization, an important part of the managerial union in many countries, it has recognized the more and more excellent paper of their companies in the economic, environmental and social transformation of the geographical areas where they act, because of the impact that you/they generate and they reach. These behaviors or ways of assuming aware commitments of contributing with the sustainable development and the improvement of the quality of the workers' life, their families, the community and the society in general, on the base of efficient and effective economic processes, it contains the acting of the Managerial Social Responsibility. The present work has as objective to evaluate the practices in Managerial Social Responsibility of the Genetic Cattle Company Camilo Cienfuegos. For the realization of this, the following methods were used: the historical-logical, systemic and statistical with their different ones technical. As a result an evaluation is obtained on the part of the surrounding population to the entity, as well as of its workers, technicians and specialists of like they perceive the Managerial Social Responsibility carried out by the study entity, starting from excellent aspects related with five fundamental environments: organizational environment, economic and financial environment, environmental environment, environment of programs and projects and innovative and technological environment, which allowed to classify as positive the acting of the Managerial Social Responsibility in this entity.


A better understanding of the natural and cultural heritage value is the basis for dealing with the relationship between protection and utilization of the world heritage,and it is also the precondition to solve the problem of"urbanization,commercialization,artificialization"of the heritage sites.Based on the system theory,after reviewing different views and interpretations of the natural and cultural heritage value,this paper proposes the value system of natural and cultural heritages in China,which can be divided into three parts:the background value,the direct applicable value and the indirect derivative value.This value system is multi-leveled with the background value being the foundation of the other values,so we should make use of the heritage with a reasonable manner at the precondition of protection.At the same time,these three values exist in different spatial areas,namely,the background value mainly exists within the range of heritage sites,the direct applicable value exists in the heritage sites and their adjacent regions,and the indirect derivative value exists mainly outside the range of heritage sites.Therefore,to protect and use the natural and cultural heritages,we should stick to three basic principles:firstly,protecting the background value strictly to ensure that the authenticity and integrity of heritage is not compromised;secondly,using the direct applicable value appropriately through"function comprehensive utilization,product comprehensive development and industrial comprehensive development";thirdly,giving full play to the indirect derivative value to stimulate the local social and economic development.


The influence of information technologies on the general system of enterprise management has been studied, the efficiency of introduction of billing control systems at local enterprises has been analyzed, the influence of information technologies on the quality of the adopted management decisions is substantiated, the mathematical model of managerial activity of the modern manager towards the enterprise has been proposed.


At present, glass is common in our lives. Glass has excellent physical and chemical properties. It has high compressible strength, high hardness, transparency, good stability, and is not easily deformed. It is an inorganic non-metallic material with a wide range of uses. With the development of science and technology, the scope of application of glass is more and more extensive, and the strength requirements for glass are also getting higher and higher. How to improve the impact resistance of tempered glass, this article studies the heat treatment processing technology and parameter adjustment, and the appropriate process route through appropriate heat treatment methods, so as to improve the impact resistance of tempered glass. Inspection has verified the rationality of the process.


In this paper, the energy release energy corresponding to the unit crack propagation obtained from the displacement controlled load-displacement plot is equalized to the elastic energy release rate, and the variation of stiffness based on the crack length is obtained. For this purpose, instead of measuring the amount of crack mouth opening in the single edge-cracked tensile specimen, the extensiometer elongation amount was taken in the middle part of the specimen. Thanks to the equality of the stiffness to the crack length, the transformation of the load-displacement curve into the material resistance curve was realized.


Blue LED light irradiation is currently under investigation because of its effect in wound healing improvement. In this context, several mechanisms of action are likely to occur at the same time, consistently with the presence of different light absorbers within the skin. In our previous studies we observed the wound healing in superficial abrasions in an in vivo murine model. The results evidenced that both inflammatory infiltrate and myofibroblasts activity increase after irradiation. In this study we focused on evaluating the consequences of light absorption in fibroblasts from human cells culture: they play a key role in wound healing, both in physiological conditions and in pathological ones, such as keloid scarring. In particular we used keloids fibroblasts as a new target in order to investigate a possible metabolic or cellular mechanism correlation. Human keloid tissues were excised during standard surgery and immediately underwent primary cell culture extraction. Fibroblasts were allowed to grow in the appropriate conditions and then exposed to blue light. A metabolic colorimetric test (WST-8) was then performed. The tests evidenced an effect in mitochondrial activity, which could be modulated by the duration of the treatment. Electrophysiology pointed out a different behavior of irradiated fibroblasts. In conclusion, the Blue LED light affects the metabolic activity of fibroblasts and thus the cellular proliferation rate. No specific effect was found on keloid fibroblasts, thus indicating a very basic intracellular component, such as cytochromes, being the target of the treatment.


......................................................................................................................................... ii Table of Contents ......................................................................................................................... iii Yahguadangang (author's respects)........................................................................................... iv Acknowledgements ........................................................................................................................v Chief Dan George Epigraph ....................................................................................................... vi CHAPTER ONE: Building Bridges Between Academia and Indigenous Literatures
 1.1 Outlining the Project's Parameters .............................................................................................. 1 1.2 Finding the Appropriate Words ................................................................................................... 3 1.3 Appropriation and Abrogation..................................................................................................... 8 1.4 Make it New: Translation and Hybrid Texuality....................................................................... 11 CHAPTER TWO: Cross-Culturally Rendering Oral Myth in Robert Bringhurst's A Story as Sharp as a Knife
 2.1 Anthropology and Ethnopoetics ................................................................................................ 17 2.2 Learning to Hear the Voice in Text ........................................................................................... 21 2.3 The Sound of Myth.................................................................................................................... 27 2.4 Rendering the "Other" in the Self.............................................................................................. 32 CHAPTER THREE: Creating Dialogic Spaces in Harry Robinsons Write it on Your Heart
 3.1 Storytelling as a Cultural Pedagogy .......................................................................................... 37 3.2 "Interfusional" Writing.............................................................................................................. 41 3.3 The Whirlwind of History ......................................................................................................... 45 3.4 Performing Audience................................................................................................................. 51 CHAPTER FOUR: Resistance as Cultural Translation in War Party's The Reign
 4.1 Hip Hop as a Multicultural Pedagogy ....................................................................................... 55 4.2 Contesting Space: Abrogation and Reinscription...................................................................... 60 4.3 Hybrid Orality and Hypertext Poetics ....................................................................................... 66 4.4 Antiphony: Calling Together, or Calling Away ........................................................................ 71 CHAPTER FIVE (Outro): Listening Scholars
 5.1 First Nations Critical Practice in the 21st Century ..................................................................... 78 Endnotes .......................................................................................................................................82 Works Cited..................................................................................................................................85


This discussion of the mentor/protege relationship in the library setting begins by examining the benefits of mentoring for both individuals and the organization. Characteristics of mentors, guidelines for self-assessment of strengths and weaknesses for a potential mentor, and protege characteristics that will attract a mentor are outlined. Communication skills essential to mentoring are then described, including active listening, giving and receiving feedback, counseling, coaching, and managing conflict and disagreement. Conditions within the organization that encourage or discourage the development of mentor relationships are summarized, and the paper concludes with a discussion of ways that librarians can promote leadership through mentoring. (10 references) (MES) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. ****************** ***** ** ***** ******************************** ********* -4 U.S. DEPARTMENT OF EDUCATION Once of Educational Research and Improvement . EDUCATIONAL RESOURCES C) INFORMATION CZ, CENTER (ERI 111This document has been reproduced as teN received from the person or organization grrginating at 0 Minor changes have been made to Improve reproduction gualdy Lima Pewits of view or oPmons stated in t his ment do not necessarily represent official OEM positron or policy MENTORING FOR LEADERSHIP


We consider the first price sealed auction which the bidders utility functions is u(x)=x a(0a+∞) and the biders conserve value is drawn from uniform distribution in [0,1].The Bayes Nash equilibrium bidding strategy has been obtained in the symmetry auctions and in the asymmetry auctions, if the bidders utility functions is u i(x)=x β i (β i0,i=1,2), for sufficiently large one of β i the auction is not pareto efficient.


Pseudomyxoma peritonei (PMP) is a condition characterized by the accumulation of mucinous material in the peritoneal cavity (gelatinous ascites). Pseudomyxoma peritonei is an uncommon condition in which mucinous ascites causes progressive abdominal distension and gastrointestinal dysfunction. We present a case of 44 year old female who presented with gradually progressive abdominal distension since 6 months. An ascitic tap was performed and the fluid was sent for cytological study. Cytology showed pools of acellular mucin. On laparotomy there was mucinous material in the abdomen that was evacuated. Appendix and omentum were found to be thickened, hence appendicectomy was done and omental biopsy taken. Histopathological diagnosis of well differentiated mucinous adenocarcinoma of appendix with rupture and mucinous ascitis was made.


The most recent building trend is going large, high rise, high strength as overlarge project is developing in domestic construction business.
Belite cement has properties like low heat, excellent long term strength, and durability without admixture(fly ash, silica fume). So, Belite cement is suitable for mass structure which is needed high strength, high fluidity and low heat property.
This study is to examine the possibility of site adoption microwave-use early strength estimation method. Based on the existed study related the Portland cement, the interrelation between Belite cement and microwave-use early strength estimation method is required.


Let G be a simple, connected and undirected graph with vertex set V and edge set E. A total k-labeling f : V ∪ E → {1, 2, …, k} is defined as totally irregular total k-labeling if the weights of any two different both vertices and edges are distinct. The weight of vertex x is defined as wt(x) = f(x) + ∑ xy∈E f(xy), while the weight of edge xy is wt(xy) = f(x) + f(xy) + f(y). A minimum k for which G has totally irregular total k-labeling is mentioned as total irregularity strength of G and denoted by ts(G). This paper contains investigation of totally irregular total k-labeling for caterpillar graphs S n,2,m and determination of their total irregularity strengths. In addition, the total vertex and total edge irregularity strength of this graph also be determined. The results are tvs(Sn,2,m)=⌈n+m−12⌉,tes(Sn,2,m)=⌈n+m+23⌉ , and ts(Sn,2,m)=⌈n+m−12⌉ for n, m ≥ 3.


Malignant pleural mesothelioma (MPM) is the most common form of mesothelioma and the type most often studied in prospective clinical trials.This review reports the trials that have shaped first-line treatment for patients with advanced/unresectable MPM and the real-world integration of first-line immune checkpoint inhibitors into clinical practice.


The risk game theory in the weapon equipment acquisition process is analyzed on the basis of weapon equipment acquisition requirements and the fundamental principles of principal-agent theory.Then,the equipment acquisition model based on risk sharing is established based on Mirrless-Holmstrom model,the effectiveness of the model is studied,and the model is illustrated with Edgeworth box pane diagram.The influential factors and attentions issue of the risk in the weapon equipment acquisition process are analyzed finally.The result shows that under the unsymmetrical information conditions,the effective risk-taking method is that both sides take part of the risks,which can lead to the risk-incentive behavior of the developers,and how much risk should be taken by either side is determined by total risks,risk preference of the decision-maker and risk costs.


There seemed to be rare literatures that the developmental aspects of the lipid nutrition were totally discussed about the fetus and newborn in Japan. Consideration of this issue must be contained as follows; 1) lipid metabolism in pregnancy, 2) placenta function of lipid transport, 3) fetal development and lipid metabolism, 4) Affects to infants of different sources of milk. Although medical care for prematurity has made significant advances in the past 30 years, the knowledge of the lipid nutritional support of the extremely low birth weight infants has been still scare in our country. Several essential points of important issues of lipidology of the fetus and newborn have been explained in this literature including of DOHaD concepts.


This paper deals with the effect of magnetic field of a straight Conductor on data transmission in optical fiber communication systems. A proposed method utilized to measure the stability of system performance. The experimental and simulation results demonstrated that the system instability increases effectively under the effect of external Magnetic Field. The experimental results show linear dependence of the output power fluctuation with the low magnetic field. Furthermore, for higher magnetic field values the maximum probability values of the output power close to110%. Moreover, high values of Q-factor (≥ 6) indicate a lower rate of received signal loss and the effect of the external magnetic field can be neglected in common applications.


VIII. Spectral Theory.- 1. Elements of Spectral Theory in a Banach Space. Dunford Integral and Functional Calculus.- 1. Resolvant Set and Resolvant Operator. Spectrum of A.- 2. Resolvant Equation and Spectral Radius.- 3. Dunford Integral and Operational Calculus.- 4. Isolated Singularities of the Resolvant.- 2. Spectral Decomposition of Self-Adjoint and Compact Normal Operators in a Separable Hilbert Space and Applications.- 1. Hilbert Sums.- 2. Spectral Decomposition of a Compact Self-Adjoint Operator.- 3. Spectral Decomposition of a Compact Normal Operator.- 4. Solution of the Equations Au = f. Fredholm Alternative.- 5. Examples of Applications.- 6. Spectral Decomposition of an Unbounded Self-Adjoint Operator with Compact Inverse.- 7. Sturm-Liouville Problems and Applications.- 8. Application to the Spectrum of the Laplacian in ???n.- 9. Determining the Eigenvalues of a Self-Adjoint Operator with Compact Inverse. Min-Max and Courant-Fisher Formulas.- 3. Spectral Decomposition of a Bounded or Unbounded Self-Adjoint Operator.- 1. Spectral Family and Resolution of the Identity. Properties.- 2. Spectral Family Associated with a Self-Adjoint Operator Spectral Theorem.- 3. Properties of the Spectrum of a Self-Adjoint Operator. Multiplicity. Examples.- 4. Functions of a Self-Adjoint Operator.- 5. Operators which Commute with A and Functions of A.- 6. Fractional Powers of a Strictly Positive Self-Adjoint Operator.- 4. Hubert Sum and Hilbert Integral Associated with the Spectral Decomposition of a Self-Adjoint Operator A in a Separable Hilbert Space H*.- 1. Canonical Representation Associated with a Self-Adjoint Operator Whose Spectrum is Simple.- 2. Hilbert Sum Associated with the Spectral Decomposition of a Self-Adjoint Operator A in a Separable (and Complex) Hilbert Space H.- 3. Hilbert Integral. Diagonalisation Theorem of J. von Neumann and J. Dixmier.- 4. An Application: The Intermediate Derivative and Trace Theorems.- 5. Generalised Eigenvectors.- Appendix. "Krein-Rutman Theorem"*.- IX. Examples in Electromagnetism and Quantum Physics*.- A. Examples in Electromagnetism.- 1. Basic Tools: Gradient, Divergence and Curl Operators.- 1. Introduction. Definitions (Gradient, Divergence, Curl).- 2. The Spaces H (div, ?) and H (curl, ?). Principal Properties.- 3. Kernel and Image of the Gradient, Divergence and Curl Operators. Introduction.- 4. Some Results on Regularity.- 2. Static Electromagnetism.- 1. Magnetostatics of a Surface Current.- 2. Electrostatics of a Surface Charge.- Review of 2.- 3. The Spectral Problem in a Bounded Open Domain (Cavity) with Perfect Conductor Boundary Conditions.- 1. Definition and Fundamental Properties of the Maxwell Operator A in an Open Domain ? ??3 with Bounded Boundary ? = ??.- 2. Spectral Properties of A in a Bounded Open Domain (Cavity).- Review of 3.- 4. Spectral Problems in a Wave Guide (Cylinder).- 1. Introduction.- 2. The Maxwell Operator A in a Cylinder. Definition of D (A) and the Trace Theorem.- 3. Study of the Kernel of the Operator A in the Space H.- 4. Spectral Decomposition of the Maxwell Operator A in the Case of a Cylinder ("Wave Guide") ? = ?T x ? with ?T a Connected and Regular, Bounded Open Domain in ?2.- Spaces Utilised.- B. Examples in Quantum Physics.- on the Observables of Quantum Physics.- 1. Operators Corresponding to the Position, Momentum and Angular Momentum Observables.- 1. System Consisting of a Single "Non Relativistic" Particle Without Spin, Located in the Space ?3.- 2. System Consisting of a Single "Non Relativistic" Particle with Spin (1/2) in ?3.- 3. System of a Single Particle Located in a Bounded Domain ???3.- 4. System of N Distinguishable non Relativistic Particles in ?3.- 5. System of N Indistinguishable non Relativistic Particles in ?3.- 6. System of a Single Free Relativistic Particle. Case of a Particle with Spin 1/2 Satisfying the Dirac Equation.- 7. Other Cases of Relativistic Particles.- 2. Hamiltonian Operators in Quantum Physics.- 1. Definition of Hamiltonian Operators as Self-Adjoint Operators.- 2. Hamiltonian Operators and Essentially Self-Adjoint Operators.- 3. Unbounded Below Hamiltonian Operators.- 4. (Discrete) Point Spectrum, and Essential Spectrum of (Hamiltonian) Self-Adjoint Operators.- 5. Continuous Spectrum of (Hamiltonian) Self-Adjoint Operators.- Appendix. Some Spectral Notions.- 2. "Continuous Operational Calculus" for a (Bounded) Normal Operator.- 3. "Continuous Operational Calculus" for an (Unbounded) Self-Adjoint Operator.- 4. Simultaneous Spectrum of a Commutative Family of (Bounded) Normal Operators.- 8. von Neumann Algebras.- 9. "Bounded Operational Calculus".- 10. Maximal Commutative von Neumann Algebras.- 11. "Maximal" Spectral Decomposition. "Complete Family of Observables which Commute".- Table of Notations.- of Volumes 1, 2, 4-6.


A note on the state-of-the-art and the perspectives of research into extreme hydrological events and the related technology is offered. The note serves as the introductory material for the set of contributions assembled in the volume. Structure of the volume is explained, consisting of three sections, in which particular components of the broad problems of floods and droughts are elaborated. Comments on the emerging research needs in the area of extreme hydrological events are also offered.


Starting from the establishment of generalized predictive model based on neural network, LM optimization algorithm is applied to the perdictive control model for study in order to solve these problems that the training speed of the BP network is slow and it is easy to trap into the local minimum.Generalized predictive control and neural network which has the capability of approaching any nonlinear function are combined to forecast the future outputs of the system.LM algorithm is used instead of gradient descent method to optimize controller parameters and it makes full use of Jacobian matrix information identified by neural network.The result of Matlab simulation indicates that the neural network using LM algorithm has the feature of fast convergence rate,model of high precision and good robustness,which is more suitable for real-time nonlinear control.


Due to microgrids low inertia and low capacity, recovering stable operating conditions of microgrids depends primarily on the dynamic performance of control systems. It also depends on the technological constraints of power electronic converters related to the low thermal inertia of semiconductors devices, which requires limiting the transient current under large-disturbances. This paper investigates the large-signal stability of an islanded microgrid fed by a controlled grid-forming inverter in voltage-frequency mode and a controlled grid-following inverter in current control mode. It analyzes the dynamic response models of each inverter control system connected to an islanded microgrid and the interaction between the inverter control systems under a three-phase ground fault. Time-domain simulations are carried out with Matlab/SimscapePowerSystems. The obtained results show that grid-forming inverter imposes the dynamic response of the islanded microgrid through dynamics of the inner current control loop. Whereas grid-following inverter acts as a constant current source whose dynamics is influenced by the grid-forming inverter.


The method for coating a hollow interior cooling blades of the gas turbine (1) is provided, in this way, the outer coating comprising MCrAlY-based adhesive layer (6), ceramic thermal barrier layer of zirconium oxide and (9) (5 ) is a blade (base material of the blade (1) outside the 1) (3) to be coated, Cr diffusion layer (7) inside coatings comprising (4), the blade (inner blade 1) (1) It is applied to the base material of (3). Whereby MCrAlY-based adhesive layer (6) is applied to the finished blade (1). At the same time, with the inner coating (4), Cr diffusion layer (7) is also applied to the MCrAlY-based adhesive layer (6) of the outer coating by chemical vapor deposition (5). Thereafter, Al diffusion layer (8) and the outer brittle Al accumulation layer, by chemical vapor deposition, it is applied to the coated adhesive layer of Cr diffusion layer (7) (6). Thereafter, the outer brittle Al accumulation layer is removed by polishing, the ceramic heat insulating layer (9) is applied to the Al diffusion layer (8).


expanded the horizons of interventional endoscopy [1]. Starting with rigid optical endoscopes that could access only either end of the digestive system, endoscopy evolved to enable visualization of the en− tire gastrointestinal tract with the devel− opment of capsule endoscopy and dou− ble−balloon enteroscopy [2]. However, the biliary−pancreatic system still re− mained a side track. The available bili− ary−pancreatic endoscopes are expensive, suboptimal, and not widely available [3, 4]. Optimal visualization of the bile duct lumen enabling direct interventions through an adequate working channel re− mains a dream. Working under the odds of third−world realities, we recently adapted the diagnostic double−balloon enteroscope to serve as a peroral choledo− choscope, without the need for an expen− sive mother±baby system. A 65−year−old man presented with a 6− week history of painless progressive jaundice and fever. There was evidence of severe extrahepatic distal biliary ob− struction on abdominal CT. Endoscopic retrograde cholangiopancreatography showed a large intraluminal filling defect in the dilated common bile duct and a suspected stricture at the hilar region (l" Fig. 1). Proximal biliary access failed despite a sphincterotomy and multiple attempts with different accessories. With negative biliary brush cytology and noninforma− tive magnetic resonance cholangiopan− creatography, a percutaneous biliary ac− cess seemed inevitable due to the lack of a choledochoscope. Encouraged by prior extensive experience with double−bal− loon enteroscopy, cholangioscopy was performed using the 8.5 mm diagnostic Fujinon double−balloon enteroscope after balloon dilation of the proximal biliary stricture (l" Video 1). Successful endoscopic biliary drainage was accomplished under direct vision, after biopsy of the large papillary projec− tions observed in the proximal common bile duct near the hilum (l" Fig. 2 a, b). Histopathology confirmed papillary cyst− adenocarcinoma that was subsequently operated on (l" Fig. 2 c). To conclude, thinking outside the box, we describe an alternative approach for chol− angioscopy with a 2.8 mm working chan− nel that would enable most endoscopic interventions in the dilated biliary tree. Development of a dedicated peroral cho− ledochoscope to extend therapeutic op− tions seems long overdue.


This study was conducted to evaluate the feeding value of fungi treated Jatropha curcas kernel cake on feed intake, weight gain /loss , digestibility coefficient and blood parameters of West African dwarf goat. Five diets were formulated with diet A (control, without Jatropha curcas kernel cake); B (50% Penicillium treated Jatropha curcas kernel cake +50% Soybean cake), C (50% Aspergillus niger treated Jatropha curcas kernel cake + 50% Soybean cake), D (100%Penicillium treated Jatropha curcas kernel cake ) and E (100% Aspergillus niger treated Jatropha curcas kernel cake). The animals (n=15) were randomized against the experimental diets in a completely randomized design model for a 56 day period. The results revealed highest crude protein intake for diet A and the least for diet E. The ether extract (EE) and crude fibre (CF) consumption were significantly higher for the control diet (A) compared to the fungi treated based diets. The crude protein digestibility was highest in diet A and least in diet C. The serum and haematological values are within the normal range for goat. It was concluded that West African dwarf goat can be fed a diet consisting of 50% Aspergillus niger treated Jatropha curcas kernel cake /or 50% Penicillium treated Jatropha curcas kernel cake in a mixed ration.


Analyzing 16S ribosomal RNA (rRNA) sequences allows researchers to elucidate the prokaryotic composition of an environment. In recent years, third-generation sequencing technology has provided opportunities for researchers to perform full-length sequence analysis of bacterial 16S rRNA. RDP, SILVA, and Greengenes are the most widely used 16S rRNA databases. Many 16S rRNA classifiers have used these databases as a reference for taxonomic assignment tasks. However, some of the prokaryotic taxonomies only exist in one of the three databases. Furthermore, Greengenes and SILVA include a considerable number of taxonomies that do not have the resolution to the species level, which has limited the classifiers' performance. In order to improve the accuracy of taxonomic assignment at the species level for full-length 16S rRNA sequences, we manually curated the three databases and removed the sequences that did not have a species name. We then established a taxonomy-based integrated database by considering both taxonomies and sequences from all three 16S rRNA databases and validated it by a mock community. Results showed that our taxonomy-based integrated database had improved taxonomic resolution to the species level. The integrated database and the related datasets are available at https://github.com/yphsieh/ItgDB.


Exhibitions Dates to note are: Sunday, 21st November 1999. West of England Creepy Crawly Show, Newton Abbot racecourse, Devon. Sunday, 5th December 1999. Midlands Entomological Fair. At Kettering Leisure Village. Open 1030-1630. Admission: £2.00 adults, £1.00 children and OAPs. The venue is just off junction 8 of the A14 and is usually well signposted. Sunday 16th April 2000. Midlands Entomological Fair. At Kettering Leisure Village.


The subject of ''competitive solubility" has been dealt with in two previous communications of this series, parts II and XI. In both of these, emphasis was laid on the fact that electrolytes and non-electrolytes are alike active as precipitants of salts from aqueous solutions and it was implied that no "theory" of the process of dissolution which dose not take this fact into account can be satisfactory. The activity of the several precipitants studied was expressed in terms of their apparent molecular hydration—that is to say, the method of treatment adopted involved the evaluation of the amount of water thrown out of action as solvent water by the precipitant: ears was taken, however, to point out that this artifice was introduced merely on the Around of convenience and that the expression "apparent moleoular hydration" was not to be interpreted literally.


Graph-based binding algorithm is very popular for a retargetable compiler in computer science. Binding number, one indicator to better understand graph, is an important characteristic quantity of graph. Constant work have been done on binding number computation by many researchers for some special graphs, such as product graphs, multi-product graphs, multiple cartesian product graph of complete bipartite graph. This paper is meant to present a polynomial algorithm of the generality graph binding number through the maximum network flow algorithm. We convert binding number computation into calculating the capacity of a minimum cut by constructing directed network with some parameters based on the transformation idea from the least ratio to the least difference. In the latter part,the time complexity of the polynomial algorithm is analyzed and given.


There is little information concerning a nitrogen metabolism of the cariogenic streptococci included in the species Streptococcus mutans. Carlsson (Caries Res 4: 305-320, 1970) examined nutritional requirements of the S mutans and found that for an anaerobic growth the ammonium salts can be used as a sole source of nitrogen and for an aerobic growth only one amino acid-glutamic acid, glutamine, aspartic acid, or asparagine-is needed. Krzeminski (Czas Stomatol 26: 351-355, 1973) showed that the S mutans strain FA-1 has three active basic transamination systems, that is, with a-ketoglutaric acid, pyruvic acid, and oxalacetic acid as acceptors of amino groups. There is still a lack of information about the free amino acid pool of the cariogenic streptococci. S mutans strains FA-1, BHT, and HS-1 were examined. The organisms were cultivated aerobically at 37 C in a medium containing 2% Tryptose,a 0.5% Yeast Extract,a 0.5% glucose, 0.2% NaCl, 0.4% KH2PO,, 0.2% Na,HPO4, 0.1% K2C03, 0.012% MgSO4, and 0.0015% MnSO4. The cells were harvested by centrifugation at 4 C, washed three times with cold 0.85% NaCl, and resuspended in distilled water to a density of about 2.5 to 3 mg dry weight/ml. The amino acids were extracted from the cells by heating the suspension at 100 C for 15 minutes. Then the cells were centrifuged and the amino acids in the supernatant fluid were determined quantitatively by a ninhydrin method (MOORE and STEIN, J Biol Chem 211: 907-914, 1954) and qualitatively by means of two-dimensional ascending paper chromatography (PASIEKA, Can J Biochem Physiol 38: 1137-1147, 1960) and paper electrochromatography (WRONSKI, Chem Anal 10: 1001-1006, 1965). After 20 hours of growth, the quantity of the free amino acid pool in strains FA-1, BHT, and HS-1 was 0.36, 0.45, and 0.27 ,umoles/mg dry weight (calculated according to the standard curve for leucine). The pool approximated 4.7,


In this paper, we propose a new rate-control scheme, called splitting, to construct low-rate codes from high-rate codes by splitting rows of the parity-check matrices of LDPC codes, which can construct ratecompatible LDPC codes having good initial transmission performance. Good low-rate codes can be constructed by making the number of distinct check node degrees as small as possible after splitting. The proposed scheme achieves good cycle property, low decoding complexity, and fast convergence speed, especially compared to the puncturing. Especially, rate-compatible repeat accumulate-type LDPC (RA-Type LDPC) code is constructed using splitting, which covers the code rates from 1/3 to 4/5. Through simulation it is shown that this code outperforms other rate-compatible RA-Type LDPC codes for all rates and can be decoded conveniently and efficiently.


An improved quantum neural network model and its learning algorithm are proposed for fault diagnosis of the coal electrical haulage shearer in order to on line monitor working states of the large mining rotating machines. Based on traditional BP neural network, the three-layer quantum neural network is constructed to combine quantum calculation and neural network for the error correction learning algorithm. According to the information processing mode of the biology neuron and the quantum computing theory, the improved quantum neural network model has the ability of identifying uncertainty in fault data classifications and approximating the nonlinear function for different fault types to monitor the electrical motor voltage, current, temperature, shearer location, boom inclination, haulage speed and direction in the coal electrical cutting machines. The theory analysis and simulation experiment results show that the control performances and the safety reliability of the coal shearer are obviously improved, while the quantum neural network model is applied to the nonlinear feature fault diagnosis of the coal electrical haulage shearer.


BACKGROUND
Endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA) of mediastinal lymph nodes has been found to be more accurate than standard TBNA in the setting of malignancy. In patients with suspected sarcoidosis, the smaller ultrasound needle may yield inadequate material to make a histologic diagnosis of granulomatous inflammation. The aim of this study was to compare the diagnostic yield of EBUS-guided TBNA to TBNA performed with a standard 19-gauge needle in patients with mediastinal adenopathy and a clinical suspicion of sarcoidosis.

METHODS
A randomized controlled trial was performed in a university medical center, enrolling 50 patients (of 61 screened, 2 declined, and 9 did not meet entry criteria) with hilar and/or mediastinal adenopathy and a clinical suspicion of sarcoidosis. Twenty-four patients were randomized to undergo EBUS-guided TBNA and 26 to undergo TBNA using a standard 19-gauge needle.

RESULTS
The primary outcome measure of diagnostic yield was 53.8% vs 83.3% in favor of the EBUS-guided TBNA group, an absolute increase of 29.5% (p < 0.05; 95% confidence interval [CI], 8.6 to 55.4%). After blinded research pathology review, diagnostic yield was 73.1% vs 95.8%, in favor of the EBUS-guided TBNA group, an absolute increase of 22.7% (p = 0.05; 95% CI, 1.9 to 42.2%). Sensitivity and specificity were 60.9% and 100%, respectively, in the standard TBNA group, and 83.3% and 100%, respectively, in the EBUS-guided TBNA group (absolute increase in sensitivity, 22.5%; p = 0.085; 95% CI, 3.2 to 44.9%).

CONCLUSIONS
The diagnostic yield of EBUS-guided TBNA is superior to TBNA using a standard 19-gauge needle for sampling of mediastinal lymph nodes in patients with a clinical suspicion of sarcoidosis.

TRIAL REGISTRATION
ClinicalTrials.gov Identifier: NCT00373555.


Abstract
It appears that the risk of crop production under dry land conditions would be increased due to climate change in the next future decades. Recently, because of in most dryland regions, water use efficiency (WUE) is low due to undesirable production management. Water stress affects many physiological processes, involved in wheat (Triticum aestivum L.) yield formation. In order to improve economy of water use, regulation of root and shoot growth is important. In this study effects of different levels of nitrogen fertilizer and plant growth retardant (Chlormequat Chloride) on grain, phytomass yield and WUE of four rainfed wheat cultivars were examined in a field experiment during 2006-07 and 2007-08 growing seasons in College of Agriculture, Shiraz University located in Badjgah. The results showed that differences between cultivars for grain yield, phytomass and WUE were significant. Effects of chlormequat chloride and nitrogen on grain and phytomass yield were significant. In the first year the highest grain yield and phytomass production (192.4 and 431.2 g/m2, respectively) were obtained from Nicknejad cultivar, Chlormequat Chloride application and using 80 kg/ha nitrogen, and in the second years from Azar-2 cultivar (121.5 and 333.5 g/m2, respectively). Chlormequat chloride and nitrogen had significant effects on WUE in both years. Interaction of chlormequat chloride and 80 kg/ha nitrogen application in both years on WUE were significant (0.95 and 2.35 g/m2/mm, respectively). It appeared that nitrogen and chlormequat chloride application with increase root expansion and proliferation improved soil water uptake. It might be recommended that selecting resistant cultivars to later season drought stress, together with application of chlormequat chloride and nitrogen fertilizer have beneficial effects on increase of WUE of rainfall and could improve wheat grain yield under rainfed conditions.

Keywords: Dryland Wheat Cultivars, Plant Growth Retardant, WUE, Drought Stress, Grain Yield


The Judicial Reforms of 1864 have long been recognized as a major turning point in Russian history. Not only did they represent the first legal limitation on the absolute power of the autocracy, they also established, despite numerous obstacles, some of prerevolutionary Russia's most durable liberal institutions: the jury, the independent judiciary, and the legal profession (advokatura). Without question these reforms had a profound impact on Russian society, yet at the same time it must be emphasized that the Judicial Reforms did not, as is sometimes suggested, symbolize the instant transformation of the entire Russian judicial system. In reality these reforms took more than thirty years to implement-Omsk and Tashkent did not come under their jurisdiction until 1898-and even in the districts where the reforms were introduced, remnants of the pre-1864 legal system survived and prospered. One of the main paradoxes of tsarist Russia's legal development, therefore, was that pre-1864 legal traditions and institutions continued to influence Russia's emerging legal consciousness long after the Judicial Reforms had been implemented. The peasant volost' courts provide the best-known example of this phenomenon. By restricting peasants to their prereform local courts and keeping them subject to peasant customary law, the autocracy removed approximately 80 percent of the population from the jurisdiction of the reformed courts. The courts were not the only judicial institution, however, that continued to be influenced by its prereform past. The advokatura-the established Bar-faced a similar predicament; before it could establish its professional supremacy, it had to confront the descendants of the prereform legal profession. Prior to 1864, Russia's legal practitioners-commonly known as the striapchie (scriveners)-existed as an amorphous mass, an "absolutely free profession" as one commentator later called it, where every citizen not specifically forbidden by law had the right to serve as a legal representative in court.l In sharp contrast, the Judicial Reforms created a new


Introduction: AML pts who relapse after allogeneic hematopoietic cell transplantation (HCT) face poor clinical outcomes and short overall survival (OS) (Schmid et al, Blood2012). The delivery of optimal salvage therapy is challenging as some pts do not tolerate high intensity regimens, and lower intensity therapies may not yield sufficient disease control. Favorable responses in older, treatment naïve AML pts with venetoclax (VEN) in combination with low-dose cytarabine (LDAC) or DNA methyltransferase inhibitor (DNMTi) led to its approval. Off-label use in relapsed/refractory AML is increasing (DiNardo et al, Am J Hematol2018; Aldoss et al, Haematologica2018). We retrospectively evaluated the overall response rate (ORR = CR+CRi+PR+MLFS) and report our clinical experience with VEN-based salvage in post-HCT relapsed AML.
 Methods: After IRB approval, consecutive pts with post-HCT relapsed AML treated with VEN+LDAC or VEN+DNMTi from May 2018 to July 2019 were retrospectively analyzed. Selection of VEN partner and dosing were at the discretion of the treating physician based on institutional guidelines and published prescribing information. Responses were assigned based on the AML IWG criteria. The Kaplan-Meier method was used to describe OS. ORR and treatment complications were summarized via descriptive statistics.
 Results: 18 pts with post-HCT relapsed AML who received at least 1 cycle of VEN-based salvage chemotherapy were included. Median age at HCT was 64.5 years (range 34.5-73.7 years). Most pts were poor risk: 6/18 pts had an antecedent hematologic malignancy, 12/18 had an abnormal or complex karyotype (CK) prior to HCT, and 4/12 pts with CK also were TP53mut. 15/18 (83.3%) received reduced intensity conditioning and MUD was the predominant graft type (50%). All pts received PBSCs. Additional disease and response characteristics are reported in Fig 1A. Median time from HCT to relapse was 5.5 mos (range: 0.9 to 44.9 mos); 27.8% of pts relapsed within 100 days and 55.6% relapsed within 6 mos of HCT. At relapse, 1 patient had grade 2 aGVHD and 1 had severe, extensive cGVHD. No pts experienced a GVHD flare or progression during treatment. 14/18 (77.8%) of pts were receiving immunosuppressive therapy (IST) at relapse and received VEN concurrently with IST.
 VEN-based salvage chemotherapy began shortly after confirmed relapse (range: 4-46 days); 4/18 pts received VEN with LDAC and 14/18 were treated with a DNMTi partner. 15/18 pts were evaluable for response. IWG responses were seen in 8 pts with an ORR of 53%. There were 0 CR, 6 CRi, 0 PR, 2 MLFS, 7 pts had progressive disease (4 by BM, 3 by PB, Fig 1B). 3/18 additional pts had a ≥50% reduction in circulating blasts indicating treatment effect but were non-evaluable given lack of surveillance BM biopsy. Pts received a median of 2.5 cycles (range 1-9). 15/18 pts had treatment held or delayed due to fever/infection (7), PB cytopenias (4), combination (3), or non-hematologic toxicity (1). 6/8 pts who achieved a CRi/MLFS had VEN dosing reduced or administered as a single-agent. One patient achieved CRi with dose interruptions lasting ≥3 mos, maintained this response, and subsequently cleared a TP53 mutation.
 The majority of pts 13/18 (72.2%) experienced infectious complications during treatment: 7 developed bacterial pneumonia (4 associated with sepsis), 4 fungal penumonia, and 2 oral infections (both associated with sepsis). 8/18 pts had active infections at the time of death. Time from HCT or IST status did not appear to impact the frequency or severity of infectious complications. After a median of 2.7 mos of follow up (range 0.6-8.9 mos), the mOS after the start of VEN was 130 days. Consolidation with donor lymphocyte infusion or second HCT is planned for several pts.
 Conclusions: Transplant related- and disease related-mortality are difficult to disentangle in post-HCT AML relapse making it challenging to ascertain the benefit of therapy. In this cohort, the majority of pts relapsed within 6 mos of HCT and were receving IST at the start of salvage therapy. In spite of this, VEN-based salvage induced meaningful responses. To convert these responses to long term survival benefit, as VEN-based salvage is more widely used in this setting, consideration of immunosuppression and previous marrow injury should inform alternative dosing regimens, careful monitoring for infectious complications in close follow-up, and broad spectrum antimicrobial prophylaxis.

 Byrne: Karyopharm: Research Funding. Dholaria:Celgene: Honoraria. Ferrell:Incyte: Research Funding; Agios: Consultancy; Forma Therapeutics: Research Funding; Astex Pharmaceuticals: Research Funding. Jagasia:Kadmon: Consultancy; Incyte: Consultancy; Janssen: Research Funding. Strickland:Astellas Pharma: Consultancy; Sunesis Pharmaceuticals: Research Funding; AbbVie: Consultancy; Jazz: Consultancy; Kite: Consultancy; Pfizer: Consultancy. Savona:Sunesis: Research Funding; AbbVie: Membership on an entity's Board of Directors or advisory committees; Boehringer Ingelheim: Patents & Royalties; Celgene Corporation: Membership on an entity's Board of Directors or advisory committees; Incyte Corporation: Membership on an entity's Board of Directors or advisory committees, Research Funding; Karyopharm Therapeutics: Consultancy, Equity Ownership, Membership on an entity's Board of Directors or advisory committees; Selvita: Membership on an entity's Board of Directors or advisory committees; Takeda: Membership on an entity's Board of Directors or advisory committees, Research Funding; TG Therapeutics: Membership on an entity's Board of Directors or advisory committees, Research Funding.

 Venetoclax use in relapsed/refractory AML


Diphterial intoxication was established in rabbits by means of bolus 1 DLM/kg intravenous injection of diphterial toxin. Different types of N-acetyl-beta-1)-galactosaminidase's activity were determined in lysosomal fraction which had been obtained after ultracentrifugation of the left and right ventricles' tissue of the heart. It has been found that the mechanism of fixation's reinforcement of this enzyme exists in lysosomes in case of increasing of its activity. This mechanism was damaged on the different stages of diphterial intoxication that influenced negatively the heart's contractility.


We have generated antibodies against a synthetic peptide corresponding to the sequence of human von Willebrand factor (vWF) between residues Ser17" which includes the Arg-Gly-Asp sequence common to several adhesive molecules. Two anti-peptide antibodies, one polyclonal, and one monoclonal reacted with native vWF and inhibited its binding to platelet glycoprotein (GP) IIb-IIIa, but showed negligible cross-reactivity with fibrinogen, fibronectin, and vitronectin, three other molecules that contain the sequence Arg-Gly-Asp and bind to platelets. The structural bases for the specificity of the two antibodies were evaluated by testing the ability of peptides homologous to the parent sequence, but with single amino acid substitutions, to neutralize the binding of the two antibodies to vWF. The substitution of Pro1743, the residue immediately adjacent to the Arg-Gly-Asp sequence on the amino-terminal side, with Phe resulted in a peptide that failed to interact with either antibody. Thus, is important  for maintaining a peptide conformation recognized by two antibodies pecific for the GP IIb-IIIa-binding domain of vWF. Other residues important for optimal peptide reactivity with the polyclonal antibody were Ser17", Arg'744, and G ~ Y ' ~ ~ ' , whereas G ~ Y ' ~ ~ ' , G ~ Y ' ~ ~ ' , and Asp1746, but not Arg1744, were important for reactivity with the monoclonal antibody. The epitopes of both antibodies, therefore, included at least 2 of the residues in the sequence ArgGly-Asp considered the common cell-binding site of adhesive molecules that interact with GP IIb-IIIa. Nevertheless, both antibodies reacted only with vWF. These studies demonstrate that peptide-specific antibodies, unlike the promiscuous G P IIb-IIIa receptor, can recognize distinctive structural characteristics of the cell-binding domain of adhesive molecules imposed by residues adjacent to the sequence Arg-Gly-Asp.


The objective of this article is to present the different strategies of promotion of education by popular culture from the activities of the Campaign "De pe no chao tambem se aprende a ler". In order to reach this goal, we carried out a literature review considering classical authors in the discussion of the theme, such as Jose Willington Germano, Moacyr de Goes and Djalma Maranhao; Theses and dissertations; Other written sources, such as newspapers, and testimonials from people who have experienced the activities of the Campaign, such as alumni and teachers. After analyzed separately, the sources were crossed, following the guidelines of Paul Thompson, and allowed us to make some initial considerations about the Campaign. We realized that there were diverse strategies for the promotion of education through popular culture, ranging from the construction of squares, theaters and libraries, to the development of cultural circles, spaces for critical literacy, based on the Paulo Freire System. We consider, then, that the Campaign was not constituted in a homogeneous way, otherwise, it acted in a diversified way, with a view to achieving the goal of the dissemination of education through Popular Culture.


The dyeability and strength properties of cotton fabric resin fmished using Finish KVSI (a DMDHEU based cross linker with built-in-catalyst) in presence of polyethylene glycol 600 (PEG 600) have been studied. The treated samples were dyed with three different vinylsulphone reactive dyes. The dyeing was evaluated by K/S values and fastness ratings while the strength properties were observed in terms of tensile and tear strengths. It has been observed that the dyeability of the crosslinked (resinfinished) fabric substantially increases in presence of PEG 600. The best results are obtained at the optimum resin cone. of 100 gpl, PEG 600 cone. of 140 gpl, curing temperature of 160°C and curing period of3 min.


ABSTRACT Electronic spectra of C6H7 radicals, α-hydrofulvenyl and cis/trans-1-vinyl-3-methylpropargyl, have been measured in the gas phase. A resonant two-colour, two-photon ionisation scheme was used after the radicals were produced in a supersonically cooled discharge source. The origin bands in D1 (2A″) ← D0 (2A″) transitions are observed at 18,734, 21,278 and 21,698 cm−1, respectively. The assignment of the spectra is based on the calculated harmonic frequencies in the D1 states and the available literature data.


An ultra-thin passive film was obtained on electroless plated Ni-P coating by treatment with a single agent chromate bath.Electrochemical tests indicated that the passivation treatment dramatically improved the corrosion resistance of the coating.The chemical composition of the passive film was analyzed with X-ray photoelectron spectroscopy(XPS),the result showed that the film comprised of O,Cr and Ni.According to the sputtering rate of Ar+ to the film,the thickness of the film was evaluated as about 6nm.By analyzing the high-resolution spectrum for the Cr 2p,it was found that the Cr in passive film was existed as trivalent compounds in the form of Cr2O3 and Cr(OH)3 And according to the XPS analysis,the formation mechanism of the passive film was discussed.


Today, military leaders have limited options when reacting to the wide range of current threats existing in our world. These threats demand forces able to deploy rapidly while possessing combat capabilities to stabilize a hostile area quickly. The Army's answer to this requirement is the Interim Brigade Combat Team (IBCT). Logistically supporting the IBCT will require the Army to develop support organizations that exploit available technologies to automate support activities, enhance situational awareness, and minimize the overall logistics footprint. The unit responsible for supporting the IBCT is the Brigade Support Battalion (BSB). One of the important missions of the BSB is to establish an ammunition transfer point (ATP) for the storage and distribution of ammunition stocks to all customer units throughout the IBCT area. This study employs an Arena 5.0 discrete-event simulation model to explore the performance of the ATP over a set of operating conditions. This set of operating conditions was selected with a statistical design of experiments using two different sets of transportation assets and ATP personnel as factors.


We prove that, for any theory defined over a space-time with boundary, the symplectic form derived in the covariant phase space is equivalent to the one derived from the canonical formalism.


The effects of radiation on the loss of ability of an irradiated Saccharomyces cerevisiae cell to produce a visible colony were studied. The studies included dependence of radiosensitivity on oxygen, temperature, cellular water, and phase state. Some generalizations on cellular radiobiology are included. (T.R.H.)


ABSTRACT This work deals with the development of optimum design tool. A finite element program is coupled with genetic algorithm to carry out the shape optimization of plates. The evaluation of performances is based on classical optimization problems. Quality of results and possible enhancement of the method are discussed


Abstract Adenosine monophosphate (AMP) is a key cellular metabolite regulating energy homeostasis and signal transduction. AMP is also a product of various enzymatic reactions, many of which are dysregulated during disease conditions. Thus, monitoring the activities of these enzymes is a primary goal for developing modulators for these enzymes. In this study, we demonstrate the versatility of an enzyme-coupled assay that quantifies the amount of AMP produced by any enzymatic reaction regardless of its substrates. We successfully implemented it to enzyme reactions that use adenosine triphosphate (ATP) as a substrate (aminoacyl tRNA synthetase and DNA ligase) by an elaborate strategy of removing residual ATP and converting AMP produced into ATP; so it can be detected using luciferase/luciferin and generating light. We also tested this assay to measure the activities of AMP-generating enzymes that do not require ATP as substrate, including phosphodiesterases (cyclic adenosine monophosphate) and Escherichia c...


The object of the present study is to investigate the dynamic of closed circuit cement mills and based on that to tune robust PID controllers applied to three actual installations. The model that has been developed, consisting of integral part, time delay and a first order filter, is based exclusively on industrial data sets collected in a period more than one year. The model parameters uncertainty is also assessed varying from 28% to 36% as the gain is concerning and 34% to 42% as regards the time delay. As significant sources of model uncertainty are determined the grinding of various cement types in the same cement mill and the decrease of the ball charge during the time. The Internal Model Control (IMC) and M - Constrained Integral Gain Optimization (MIGO) methods are utilized to adjust the controller parameters. Specially by implementing the MIGO technique robust controllers are built deriving a daily average IAE 2.3-3% of the set point value. Due to the high flexibility and effectiveness of MIGO, the controllers can be parameterized by taking into account the cement type ground and the power absorbed. Subsequently the attenuation of main uncertainties leads to improvement of the regulation performance.


In this paper, a model of the milling process of fibre reinforced composite material is shown. This classical one degree of freedom model of the milling process is adjusted for composite materials by variable specific cutting forces, which describe the fibre resistance. The stability lobe diagrams are determined numerically. Additionally, to eliminate the chatter vibration, small relative oscillations between the workpiece and the tool are introduced. Basing on numerical simulations the range of amplitude and the frequency of excitation is found for chatter reduction.


The equivalence of Maxwell-Chern-Simons Proca model and a higher order derivative extension of it with some gauge theories is analyzed from the point of view of the Hamiltonian path integral quantization.


To study the biological characteristics of sika deer antler dermis layer cells, the dermis layer of growing tip in sika deer antler was collected and a culture and cryopreservation system in vitro for the dermis layer cells was established. The results showed that the antler dermis layer cells could be cultured well within a short term in DMEM medium with 10% FBS in vitro. The cultured dermis layer cells were spindle or rhombic and the cultured cells grew to confluence after 5 days. The cells before the fourth generation appeared uniform. The edge of the cells was smooth and the cytoplasm was uniform and transparent. The cultured cells were closely arranged. The cultured cells changed into flat after the fifth generation and extended more apophysises. The edge of the cultured cells was not smooth and the cells were loosely arranged after merged. The suitable cryopreserved condition for the dermis layer cells was DMEM medium containing 5% DMSO and 10% FBS with stepwise freezing.


Background: The optimal dose of tenecteplase in acute ischaemic stroke remains to be defined. We present a pooled analysis of the two NOR-TEST trials exploring the efficacy and safety of tenecteplase 0.4 mg/kg in acute ischemic stroke. Methods: We retrospectively reviewed two multi-center PROBE trials, NOR-TEST and NOR-TEST 2A, conducted in Norway. The patients were randomized to either 0.4 mg/kg single bolus tenecteplase or standard 0.9 mg/kg alteplase. The primary endpoint was favorable functional outcome at three months (mRS 0-1) or return to baseline if pre-stroke mRS was 2. The secondary endpoints included favorable functional outcome at three months (Modified Rankin Scale 0-2), major neurological improvement and safety data. The pooling project includes a pooled analysis of patients with moderate to severe stroke (NIHSS ?6) from both trials and an additional post-hoc analysis of patients with mild stroke (NIHSS ?5) from NOR-TEST. Results: The per-protocol analysis contains 483 patients, of which 235 were assigned to tenecteplase and 248 to alteplase. In per-protocol analysis, functional outcome was better in the alteplase arm with cut-off mRS 2 (OR 0.52, 95% CI 0.33-0.80, p=0.003) and expressed by ordinal shift analysis (OR 1.64, 95% CI 1.17-2.28, p=0.004). Mortality at 3 months was higher in the tenecteplase arm (OR 2.48, 95% CI 1.20-5.10, p=0.014). Mortality and intracranial hemorrhage rates were higher in the severe stroke group randomized to tenecteplase, whereas these rates were similar for alteplase and tenecteplase in moderate and mild stroke. High age was not associated with either higher mortality or intracranial hemorrhage rates. Conclusions: Tenecteplase 0.4 mg/kg is unsafe in moderate and severe stroke and the risk of death and intracranial hemorrhage probably increases with stroke severity. A lower tenecteplase dose should be tested in future trials.


Building Integrated Photovoltaic (BIPV) technology has been one major area of PV applications. The technology provides a cohesive design, construction, and sustainable solution for the built environment (J. Benemann, 2001 and M. Oliver, 2001). It is a well-known fact that a PV cell converts only a small fraction of the absorbed solar radiation into electricity, and the rest into heat. The latter leads to an elevated cell temperature and consequently, a degradation of PV power. Heat removal from the PV modules is able to improve the electricity generation, and to extend the equipment working life through a reduction of thermal cycles and stresses. The means of heat removal is best through PV cogeneration (Y. Tripanagnostopoulos, 2002 and H.P. Garg, 1997).
A popular research area in PV cogeneration is in BIPV /thermal technology (M.D. Bazilian, 2002). This involves the removal and the subsequent use of waste heat through a convective airflow behind the PV panels. At the same time, the cooling effect lowers the space air- conditioning load in warm climates when the PV panels are fixed on the external wall and the thermal transmission is thus reduced. The total (electrical plus thermal) energy output of the hybrid PV system depends on a number of factors, including the incident solar radiations, the ambient temperature, the wind speed, and the absorber plate dimensions (K. Sopian, 1996). Free air convective cooling is a simple and low cost method to remove heat from the back of the PV modules and to keep the electrical efficiency at an acceptable level.
Although there is a large amount of literature on PV systems and, increasingly, building- integrated components (PV, Proc, 1995), relatively little work has been carried out on hybrid systems where use is made of the heat recovered. Recent years have seen some practical studies on the latter subject (Yang H, 1994 and Wouters P, 1996).Electrical efficiency of PV system decreases with increasing temperature, so that ventilating the facade or roof increases power production.
This paper begins by describing a method for predicting the electrical power output as a function of module characteristics, incident solar radiation and module temperature. The main purpose of this paper is to see the impact of effective cooling of a PV panel on the electricity output due to transpired solar air system. Also the results of temperature and PV output power measurements are included in this paper as for reference (collected at the UK laboratories). The experimental and predicted results (collected at KIER) are presented and discussed along with recommendations for further research and development.


Abstract The unexpected formation of the sulfur containing heterocycles (8), (9), (10), (11), (15) and further compounds (3a, b and 12) in several thermo- and photoinduced reactions of derivatives of the 2,2′-dithiodibenzoic acid is reported. The thioxanthone derivative (15) is formed by uv irradiation of the new bis-thiol ester (7a) in a novel type of aromatic photosubstitution reaction. The interesting unknown 1,2-dithiocin derivative (14) is not obtained in this photoreaction of (7a). Some aspects of the mass spectrometric behavior of the bis-thiol ester (7a) are discussed.


One of the fundamental problems of semantics is polysemy, a topic that has been approached from different positions over the years (Bolinger 1965, Kempson 1977, Pottier 1977),however one of the most interesting positions that address this problem is that of cognitive semantics (Lakoff 1987, Langacker 1991), since it proposes that the different meanings of a word are not given in a random way, but that there is a conceptual basis from which they start by losing and gaining semantic traits through the mechanisms of metaphor and metonymy. This work attempts to present an analysis of one of the movement verbs in Spanish with a greater number of meanings (Morero 2007), the verb PASAR, based on the principles of cognitive semantics, in order to show that its broad polysemy does not occur in a random way, but rather responds to a categorial systematicity.


Objective To evaluate the CT features of primary adrenal lymphoma and its relationship with pathology.Methods Pathologically proven primary adrenal lymphoma 6 cases were reviewed.There were 4 males and 2 females.The age was 18-62 years,average age was 51 years.5 cases was single tomur in unilateral,1 case was bilateral disease.The main clinical manifestations were abdominal pain,abdominal discomfort.All patients had CT scan and were treated surgically.Results CT scan showed the characters of adrenal little low-density soft tissue mass:the maximum diameter of 3-11 cm,irregularly shaped or ovalshaped,multi-state a clear,homogeneous or slightly inhomogeneous density,CT value was 30-40 HU.Lesions could be embedded or close to blood vessels and the ipsilateral kidney.The lesions were not enhanced arterial phase enhancement,CT value was 39-50 HU.The lesions showed vein phase of mild to moderate enhancement,CT value was 47-66 HU.At the delay of continuing to strengthen phase,CT value was 60-78 HU.The pathology charaters showed that:Diffuse of tumor cells under light microscope dense,more uniform size,and a large,granular chromatin,tumor stromal components was relatively small.There was no significant bleeding,necrosis and calcification.one lesion showed sheet,tumor cell necrosis.Conclusions CT scan characteristics and pathological features of primary adrenal lymphoma might have a certain correlation.

Key words:
Primary;  Adrenal lymphoma;  Tomography;  X-ray computed;  Pathology;  Diagnosis


This paper proposes a novel system for video frame freezing detection, which can be easily attached to different multimedia end-user devices for video quality monitoring. The system is implemented on commercially available multi-core1 platform in real-time.2


Various embodiments of the present invention provides a system and method for determining contact with a storage medium. By way of example, the data storage system comprising a head assembly and a data processing circuit is disclosed. Head includes a head disk interface sensor operable to provide a contact signal indicating contact between the storage medium is disposed on the head and the head. The data processing circuit is operable to process the contact signal to yield an indication of a contact between the storage medium and the head.


Jerzy Zdanowski's Speaking with their Own Voices sheds light on slavery and manumission in the Persian Gulf during the first half of the 20th century. Its main strength lies in the source material examined, around 1,000 statements made by slaves in order to obtain British manumission certificates. These personal accounts are quoted at length throughout the work, offering striking insights into the lives of slaves at the time. The book is divided into six chapters. Chapter one gives an overvie...


Microalgae are potential sources for the sustainable production of valuable chemicals including polyphenols, pigments, and ω-3 PUFAs. However, successful exploitation of these high value compounds in the food, healthcare and pharmaceutical sectors depends greatly on their effective separation, identification, and analysis after recovery from the biomass. The findings of this review paper illustrated that chromatographic methods coupled to different types of detectors have been used as a crucial part of research on microalgal polyphenols, Omega-3 Polyunsaturated Fatty Acids (ω-3 PUFAs), and pigments production through identification, measurement, sample preparation, and purification practices. Therefore, it is important to provide a comprehensive review regarding the current research in the field. The basic operating principles, parametric optimisation and detection units of common (liquid chromatography and gas chromatography) and novel chromatographic techniques (counter current chromatography, expanded bed adsorption chromatography and supercritical fluid chromatography) used to separate, identify, and quantify polyphenols, PUFAs and pigments from microalgae matrices are comprehensively reviewed.


Somaclonal variation was studied by whole-genome sequencing in rice plants (Oryza sativa L., 'Nipponbare') regenerated from the zygotes, mature embryos, and immature embryos of a single mother plant. The mother plant and its seed-propagated progeny were also sequenced. A total of 338 variants of the mother plant sequence were detected in the progeny, and mean values ranged from 9.0 of the seed-propagated plants to 37.4 of regenerants from mature embryos. The ratio of single nucleotide variants among the variants was 74.3%, and the natural mutation rate calculated using the variants in the seed-propagated plants was 1.2 × 10−8. The percentage and the mutation rate were consistent with the values reported previously. Plants regenerated from mature embryos had significantly more variants than different progeny types. Therefore, using zygotes and immature embryos can reduce somaclonal variation during the genetic manipulation of rice.


In this paper, a new genetic algorithm (GA) method is presented to solve the optimization problem in coordination of overcurrent and distance relays. The objective function (OF) is developed in a way that in addition to coordination of overcurrent relays, the coordination of overcurrent and distance relays is achieved. Various relay characteristics are considered for each overcurrent relay and the best of them is selected by GA to fulfill optimal coordination. The proposed method is applied to a sample power network. Simulation results demonstrate that the method can obtain feasible and effective solutions and, it is a promising approach for optimal coordination in practical power networks.


We argue that intentions are beliefs—beliefs that are held in light of, and made rational by, practical reasoning. To intend to do something is neither more nor less than to believe, on the basis of one's practical reasoning, that one will do it. The identification of the mental state of intention with the mental state of belief is what we call strong cognitivism about intentions. It is a strong form of cognitivism because we identify intentions with beliefs, rather than maintaining that beliefs are entailed by intentions or are components of them.


Methodology of electrical characterization of ISFETs has been described. It is based on a three-stage approach. First, electrical measurements of ISFET-like MOSFETs and extraction of basic parameters of the MOSFET compact model are performed. Next, mapping of the ISFET channel conductances and a number of other characteristic parameters is carried out using a semi-automatic testing setup. Finally, ISFET sensitivity to solution pH is evaluated. The methodology is applied to characterize ISFETs fabricated in the Institute of Electron Technology (IET). Keywords—ISFET, CMOS, electrical measurements, I-V characteristics, characterization, parameters extraction.


This paper intends to analyze film translation researches in China from 1995 to 2008 in terms of the statistics on the papers published in academic journals and the six research areas to which domestic research efforts have been devoted,pinpointing the limitations of the researches and the areas to be explored,in hopes of fostering the overall understanding of the film translation research in China,broadening our intellectual horizons and affirming its research value.


This paper discussed two respects of psychological education in schools: why the development of psychological education in schools was slower than the progress of the society,and what we should do to speed up the progress of school psychological education.


Soybean GM-RLK3 is a receptor-like kinase gene, which shares high similarity with the Arabidopsis thaliana BAM family gene suggesting a similar functional role in promoting meristem size and cell differentiation. While the functional role of RLK3 has been heavily investigated in models as well as in some agronomic crops, no studies have been conducted in soybean. The aim of this study was to examine the functional role of GM-RLK3 in soybean growth and development, in addition to assessing the response of transgenic soybean to biotic and abiotic stresses under greenhouse conditions. Stable transgenic plants for overexpression of GM-RLK3 were developed using immature cotyledon explants. Real time-PCR demonstrated the overexpression of this transgene in different tissues, and showed that GM-RLK3 was overexpressed in unifoliate tissues (52 fold increase) with lower expression in pod tissues (7.7 fold increase). Results showed that overexpression of GM-RLK3 did not improve soybean resistance to necrotrophic pathogens and abiotic stress.  Furthermore an enhanced resistance to Pseudomonas syringae pv. glycinea , as an example of biotrophic pathogens, was observed. This finding reflects activation of soybean signaling pathways involved in resistance to biotrophic pathogens. Additionally, overexpression of GM-RLK3 altered soybean growth and development by enhancing shoot biomass and number/weight of pods. Data analysis from RNA-Seq showed that overexpression of GM-RLK3 altered the transcription of other members of RLK and also of different signaling pathways involved in phosphorus, nitrogen and carbon assimilation. This study demonstrated the importance of GM-RLK3 as a regulator gene in soybean and its the overexpression provides a potential insight to improving the efficiency of soybean through manipulation of this protein.


Distributed knowledge management, intelligent software agents and XML based knowledge representation are three research challenges which are changing the face of knowledge management solutions. Distributed knowledge management allows multiplicity and heterogeneity of perspectives within organizations and consequently map technological architecture to organizational structure. In order to take the maximum advantage of distributed knowledge paradigm, software agents are well suited to handle complex interactions in social process of knowledge management. On the representation side, XML based knowledge representation moves toward popularization of knowledge representation and consequently allows machines to exchange knowledge and process it. In this article we explore structural requirements of distributed knowledge management and how to empower that with software agents and XML based knowledge representation in order to make an orchestrated knowledge management system which is compatible with the organizational structure.


Summary Reports on prenatal diagnosis in cases of skeletal dysplasia have mostly been in high-risk mothers with a suspect genetic background where the fetal lesion could probably be predetermined. We deal with routine ultrasonographic appraisal of the fetal skeleton when dysplasia is not initially suspected, and relate our experience of the lethal forms of this condition. During the 4-year period 1981 - 1984, 6 cases of skeletal dysplasia, including thanatophoric dysplasia, achondrogenesis, the Ellis-van Creveld syndrome (chondro-ectodermal dysplasia) and osteogenesis imperfecta, were detected; the ultra sonographic findings are discussed. S Afr Med J 1985; 17: 222-226. The ultrasonic demonstration of fetal abnormalities is well known, but only recently has there been extensive documenta tion of prenatal diagnosis of skeletal dysplasias. Most of these reports have been of high-risk mothers with a suspect genetic background, so that the likely lesion was predetermined. 1 ' 2 This report is concerned with the more difficult task of routine appraisal of the skeleton when dysplasia is not initially sus pected, and relates our experience of the lethal varieties. Features of the lethal bone dysplasias include limb shortening and, in some cases, a decreased thoracic/ abdominal circum ference ratio. In the second trimester careful ultrasonographic technique can show both limb shortening and decreased echo brightness of bones. 3 ' 4 Other features of the fetal skeleton, such as limb-bowing, fractures and supernumerary digits, must be correlated. The size of the thorax and abdomen must be noted and the presence of hydrops or hydramnios excluded. Radiological diagnosis is usually effective only in the third trimester, and for obvious reasons has been superseded by ultrasonography. However, it does still have a place in confirming the ultrasonic diagnosis in later pregnancy. ·


Abstract : The advanced fire supression technology (AFST) research and development program is being conducted by Olin Aerospace Research and Development program is being conducted by Olin Aerospace Company for WPAFB. The three phase program goal is to evaluate the effectiveness of gas generator technology in suppressing aircraft drybay and engine nacelle fires. This report presents the activities of phase 1, including an initital evaluation of non-filtered solid propellant gas generators, as well as select hybrid agents.


Despite successes in the use of insecticides in the control of malaria, malaria transmission continues in much of sub-saharan Africa. The search for novel methods of control (in particular genetic modification of vector populations), or of superior implementation of the currently available methods will require both greater knowledge of the population structure of the mosquito, and of the immune processes that are important in the wild. It is important to note that the mapping of novel immune genes, via genome wide association studies (GWAS) is predicated on a firm understanding of the population structure.My thesis will include a detailed description of the mosquito innate immune system based on current research and comparative genomics; this will illustrate the major pathways that might be employed in the anti-malarial response, and some potential uncharacterised genes that might be implicated in any GWAS study. It will also include a summary of what is known about the mosquito's population structure, in particular the gambiae / coluzzii speciation event and the implication of chromosomal inversions in the speciation process.I will present the development of a novel approach to the identification of chromosomal inversions; using machine-learning techniques in order to call inversion karyotypes directly from sequence, leading to calls of unprecedented accuracy.I will also present the first truly genome-wide association study to have been performed in the mosquito. Strata-controlled populations of mosquitoes were derived from the wild, including restriction on the basis of subspecies and chromosomal inversion. A two-stage mapping design was then devised in which loss-of-heterozygosity is used to identify broad regions in phenotype pools, before fine-resolution mapping by Sequenom genotyping in individuals. This was used to identify a novel locus with a phenotypic effect on infection prevalence.Finally I will describe how these techniques and findings could be important in the future application of genetic control in the wild.


In this paper we introduce the concept of the P-inversive semigroup S(P) and describe the strong P-congruences on S(P) in terms of their kernels and traces. Furthermore, we prove that any strong P-congruence on S(P) can present a strong P-congruence pair. Conversely any strong P-eongruence pair on S(P) can determine a strong P-congruence.


The intent of this investigation is to determine the elevated temperature properties of the Al3Ni-Al eutectic fiber composite. Specimens were grown from a 6.13 weight percent nickel eutectic alloy. Tensile tests were conducted over a temperature range from room temperature to ninety-seven percent of the absolute eutectic temperature. The maximum strength of the fiber composite decreased linearly from 44,000 psi at 25°C to 5,500 psi at 600°C. These strengths are superior to 2024 T6 and 7075 T6 high strength aluminum alloys at temperatures above 300°C. The room temperature strength of the as cast alloy is approximately 13,000 psi. The fiber morphology remained stable and did not appear to coarsen throughout the range of test temperatures. Deformation of the composite showed a low dependence on temperature and strain rate. Thesis Supervisor: John Wulff Title: Class of 1922 Professor of Metallurgy


This paper gives an overview of the concept of Human Resource Management, HRM. It describes the most important HRM processes and the prevalent ideas about the roles and functions of modern HRM. It is written primarily for the HRM professionals and managers in ministries and government institutions in order to provide basic knowledge on HRM in public administration for HRM training. The content is based on practical experiences of implementation of modern HRM principles and methods in Sweden and other countries. HRM in the context of reaching organisational objectives The overall aim of modern human resource management is to ensure that the organisation is able to achieve its objectives through its staff. In order to reach its objectives an organisation needs not only qualified staff but also effective and efficient systems as well as access to and effective allocation of financial resources. Institutional development therefore involves not only putting the right person at the right place at the right time, but also that the organisation provides a conducive and effective work environment and systems and that the organisation has access to adequate financial resources. In addition to human resources, the organisation needs systems like computers and financial management system, transport to reach the client, medicines in a hospital, books in the school, etc. Top management must reach a harmonious balance between all such resources and push and pull factors. HRM integrated with other systems HRM should develop objectives for its activities linked to the overall objectives of the organisation. The purpose of development of HRM objectives is to provide a direction for the HRM activities in an often turbulent environment so that, on the one hand, the business needs of the organisation, and, on the other hand the individual and collective needs of its employees can be met by the development and implementation of understandable and effective HR policies and practices. HRM objectives HR polices and practices are linked to the HRM strategy. An HRM strategy is mostly an attitude of mind, a belief in the advantages in clarifying aspirations and to make sure that what is planned is appropriate for the aims of that specific organisation and that the various parts of the HR strategy in terms of policies and practices are integrated with each other. The elementary questions for strategic planning are " Where are we going? " and " What do we need to do to get …


An extreme ultraviolet (EUV) study of the emissions from intrinsic and injected impurities in TMX is presented. Two survey spectrographs were used to determine that the major impurities present were oxygen, nitrogen, carbon, and titanium. Three absolutely-calibrated monochromators were used to measure the time histories and radial profiles of these impurity emissions in the central cell and each plug. Two of these instruments were capable of obtaining radial profiles as a function of time in a single shot.


This article presents, a microstrip filtenna with DGS (Defected Ground Structure) is used to implement a LP (Low Pass) filter is designed using a substrate of FR-4 epoxy as the dielectric material. This filtenna consists of a double N-shaped DGS as well as a double closed X-shaped DGS, to improve the performance in terms of wider operational bands, good selectivity and cut-off frequency. The 3dB cut-off frequency of this filtenna is at 2.3672 GHz. The modelled prototype of filtenna is tested and the results are compared between the simulated and the fabricated filtenna. The proposed filtenna has better gain result compared to a conventional antenna in terms of showing better rejection and out-of-band gain which subsequently reduces the interference with the adjacent frequency bands.


ABSTRA C T It is shown how to set up a mathematically elegant and fully relativistic superfluid model that can provide a realistic approximation (neglecting small anisotropies due to crust solidity, magnetic fields, etc., but allowing for the regions with vortex pinning) of the global structure of a rotating neutron star, in terms of just two independently moving constituents. One of these represents the differentially rotating neutron superfluid, while the other part represents the combination of all the other ingredients, including the degenerate electrons, the superfluid protons in the core, and the ions in the crust, the electromagnetic interactions of which will tend to keep them locked together in a state of approximately rigid rotation. Order of magnitude estimates are provided for relevant parameters such as the resistive drag coefficient.


The present work aimed to obtain a mathematical expression to calculate the amount of EDTA required to produce calcium-free and low-calcium water ((Ca 2+ ) < 5 mg L -1 ). Initially, a pilot test was carried out to confirm the effectiveness of EDTA as a chelating agent of waterborne calcium and to evaluate its effect on water pH. Five application rates of Na- EDTA (25, 50, 75, 100 and 125 mg L -1 ) were tested. The concentration of calcium in water was determined initially (before the application of EDTA) and after one hour. Linear regression analysis was performed to find out the relationship between the desired calcium concentration in water and the required EDTA: initial calcium hardness ratio. The expression ŷ = -0.0911x + 3.3628 (R² = 0.933) was derived from the linear regression analysis carried out, in which x represents the desired calcium concentration in water and y the required EDTA: initial calcium hardness ratio.


Based on the research of current SDN traffic scheduling technology, combining the advantages of reinforcement learning in strategy optimization and the characteristics of SDN network resource centralized control, and using the neural network of depth learning to fit the Q-value table, this paper proposes an intelligent multi-path routing planning method based on depth reinforcement learning. Experiments show that the method can use the characteristics of SDN to route the network traffic in multi-path according to the current state information and traffic characteristics of the network; using the advantages of reinforcement learning, it can find multiple forwarding paths for different flows that conform to their traffic characteristics, and improve the utilization rate of the network link bandwidth; and using the neural network of deep learning to fit the Q value in the traditional reinforcement learning algorithm Table.


Objective To analyze the situation of metabolic abnormalities in elderly residents of Beijing community in order to give better management and comprehensive intervention for chronic diseases.Methods Health archives and healthy lifestyle archives of permanent elderly residents over 60 years old from Dongsi community in Beijing were set up from March 2009 to November 2010 to understand the general condition,health condition and life styles.The height,weight,blood pressure,fasting blood glucose,HbA1c,TC,TG,HDL-C,LDL-C,blood uric acid and creatinine were tested.Results Among the 463 residents,the detection rates for hypertension,dyslipidemia,metabolic syndrome(MetS),diabetes mellitus,high uric acid,overweight or obesity and abdominal obesity were 69.98%(324/463),47.08%(218/463),42.12%(195/463),32.18%(149/463),24.41%(113/463),69.11%(320/463) and 71.49%(331/463) respectively.The detection rates of MetS,overweight or obesity and abdominal obesity between males and female all showed statistically significant differences(P0.05).The detection rates of hypertension,diabetes mellitus,dyslipidemia and high uric acid between males and females showed no statistically significant differences(P0.05).The detection rates of hypertension,overweight or obesity and abdominal obesity between elderly residents in different age groups showed statistically significant differences(P0.05).The detection rates of diabetes mellitus,dyslipidemia,high uric acid and MetS between elderly residents in different age groups showed no statistically significant differences(P0.05).The detection rates of hypertension,dyslipidemia,MetS,overweight or obesity and abdominal obesity between high uric acid group and normal uric acid group showed statistically significant differences(P0.05),but the detection rate of diabetes mellitus between the two groups showed no statistically significant difference(P0.05).The detection rates of hypertension,diabetes mellitus,dyslipidemia,high uric acid,overweight or obesity between MetS group and non-MetS group showed statistically significant differences(P0.05).Conclusion Elderly residents in Beijing Dongsi Community have high detection rates of hypertension,dyslipidemia,MetS,diabetes mellitus,high uric acid,overweight or obesity and abdominal obesity.The community should enhance the management of chronic diseases and early comprehensive intervention.


Laser beam welding can be a high productivity joining process, offering significant benefits over conventional welding methods. However, the need for real-time monitoring of laser welding processes is important to provide information on the possible presence of imperfections formed during welding and guarantee quality assurance in production. Laser process monitoring methods are based on the recording of physical phenomena occurring during the laser-material interaction. This paper has investigated an established optical-based monitoring method, using photodiodes responsive to either visible or near-infrared emissions, to correlate the photodiode signals with different types of weld features, imperfections and/or process anomalies. These have included occurrence of internal porosity, changes in penetration depth and beam to joint alignment, deliberate changes in laser power and intentionally poor joint preparation, cleanliness or fit-up. Also, a new type of commercially available process monitoring approa...


This practice-focused chapter describes analyzing student work (ASW), a process used by some music teachers in the United States to assess student work, analyze the results, and modify and improve instructions based on that analysis. Throughout the ASW process, specific qualities of student work are assessed using rubrics (markschemes). For teachers, the ASW process addresses the two questions "What do we do if a student is not proficient?" and "What do we do if a student is proficient and beyond?" The ASW process focuses on one aspect of student work at a time and provides data that enables teachers to modify instruction to improve student learning. Teachers can use data yielded from the ASW process in three ways: (1) to inform instruction and improve student proficiency; (2) to describe student work present and missing to construct a rubric; and (3) build consensus in scoring student work as a data team.


Reading skill has been found to be one of difficult skills to achieve for many learners of English as a Foreign Language (EFL). Importantly, based on the preliminary study, narrative texts  are deemed to be difficult.  This study was conducted to investigate the students' difficulties in reading text at a private primary school in Batu, involving 29 ninth grade students in the academic year of 2018-2019 as the samples. Employing the purposive sampling method by which the best class was selected, the researcher used10-items of a closed-ended questionnaire to collect the data. In the analysis, some aspects of the narrative text such as words, structure, language feature, character, setting, plot, moral value, and point of view were highlighted. Consistently, narrative texts were found to be the most difficult text faced by students at school. According to the English teacher, students got the difficulties because of lack of vocabulary, the use of simple past tense, and the instruction to make sense of the moral values. Further, difficulties pertain to the effort to comprehend the structure, point of view, and the words.


We consider a duopolistic market in which a green firm competes with a brown rival and each firm sells two quality-differentiated products. We study optimal non-linear contracts offered by the two firms when consumers: (i) Are privately informed about their willingness to pay for quality, and (ii) differ in their environmental consciousness. We characterize how consumers with different valuations for quality self-select into firms and show that the ranking of qualities, relative prices and profits all depend on the interplay between consumers' valuations and firms' cost heterogeneity. Interestingly, when consumers' valuations for quality are relatively low, the brown firm does not offer a low-quality variety. This contrasts with the situation of full information, in which both firms commercialize a high- and a low-quality variety. Hence, the lack of information about consumers' valuations may not only favor the green firm in terms of higher prices and profits, but also reduce the product range offered by the brown rival.