Simple Summary Hepatocellular carcinoma (HCC) represents an important health problem. At the moment, systemic therapies offered only modest clinical benefits. Thus, HCC represents a cancer extremely difficult to treat, and therapeutic breakthroughs are urgently needed. Metabolic reprogramming of neoplastic cells has been recognized as one of the core hallmarks of cancer. Experimental animal models represent an important tool that allows to investigate metabolic changes underlying HCC development and progression. In the present review, we characterize available rodent models of hepatocarcinogenesis. Moreover, we discuss the possibility that pharmacological targeting of Warburg metabolism may represent an additional tool to improve already available therapeutic approaches for HCC. Abstract Hepatocellular carcinoma (HCC) is one the most frequent and lethal human cancers. At present, no effective treatment for advanced HCC exist; therefore, the overall prognosis for HCC patients remains dismal. In recent years, a better knowledge of the signaling pathways involved in the regulation of HCC development and progression, has led to the identification of novel potential targets for therapeutic strategies. However, the obtained benefits from current therapeutic options are disappointing. Altered cancer metabolism has become a topic of renewed interest in the last decades, and it has been included among the core hallmarks of cancer. In the light of growing evidence for metabolic reprogramming in cancer, a wide number of experimental animal models have been exploited to study metabolic changes characterizing HCC development and progression and to further expand our knowledge of this tumor. In the present review, we discuss several rodent models of hepatocarcinogenesis, that contributed to elucidate the metabolic profile of HCC and the implications of these changes in modulating the aggressiveness of neoplastic cells. We also highlight the apparently contrasting results stemming from different animal models. Finally, we analyze whether these observations could be exploited to improve current therapeutic strategies for HCC.


Paper points out that flexibility or stiffness matrix methods have their common origin in energy; procedures for calculating total energy of structure; applications to analysis of truss with elastic supports and continuous beam. (22 refs.)


In order to defend the safety of our country's petroleum, to evade the risk of the price fluctuation of international oil and obtain the right to speak for the price in the international market, the fuel oil futures appeared on the market in the Shanghai Futures Exchange. But the display of the futures was hardly satisfactory, the deep reason is the imperfect market system resulting from the special system of the transition period and it ought to explore the way of development with Chinese characteristics for the petroleum industry.


Precipitation of PbS quantum dots (QDs) controlled by solid-state Ag ion migration and subsequent thermal treatment was investigated. Ag ions migrated from Ag paste applied on the surface into glass at 320°C. After following heat treatment, PbS QDs formed in the near surface area where Ag paste was coated. Sizes of the PbS QDs were larger in Ag-migrated surface regions than those in Ag-free glasses, and PbS QDs can grow at temperatures as low as 420 and 430°C. Ag nanoparticles (NPs) also formed during the thermal treatment. These results suggest that Ag NPs supplied the nucleating sites and promote the formation of PbS QDs in glasses. The spatial distribution of PbS QDs in glasses can also be controlled through solid-state Ag ion migration.


In these changing times, there are several factors that affect the quality of life, cost of living being one of them, which in turn has brought about changes in welfare. With the advent of the economic crisis of the 90s, has been affecting the quality of life of the Cuban, so research is required to endorse such a situation. The aim of this work is to evaluate the cost of living and its impact on the welfare of the Cuban working people in the province of Santiago de Cuba, in order to propose alternatives for stabilization in the period 2004-2011. The research methods applied are analysis-synthesis, inductivedeductive, historical - of course, the method of the general to the particular dialectical documentary analysis and the theoretical and methodological research. The Techniques of collecting statistical information provided by the ONEI or other agencies.


The service environment of the bridge column of the sea-crossing bridge is relatively poor, which is easily affected by the construction personnel and construction technology. The sea-crossing bridge is often in harsh weather waters such as strong winds and the current situation is difficult to predict. Therefore, it is particularly important to accurately and effectively identify and analyze the dangerous factors of bridge column construction. Based on the grounded theory, this paper selects 15 crucial risk factors for constructing the bridge column of the sea-crossing bridge from three aspects. The relationship between the indexes and the structure of the index system is analyzed by the fuzzy interpretative structural model-cross-impact matrix multiplication (FISM-MICMAC) method. The relationship between various factors is gradually analyzed and concluded from the perspective of the environment, construction, and human system analysis. The results show that the dangerous factors that play a direct role in the construction of cross-sea bridge columns mainly include the construction site conditions and material and equipment conditions, and the dangerous fundamental factors are the objective influence of natural environment and geological conditions. The proposed FISM-MICMAC model method can better identify the impact and correlation between the various risk factors, and further provide relevant suggestions for engineering practice.


Abstract : Surface pressure tests were made on a scale model of the Viking Lander Capsule at Mach number 10 and Reynolds numbers, based on the model aeroshell radius. Angle of attack was varied from -26 to 26 deg. with yaw angles of -5 and -10 included at the capsule estimated trim angle of attack of 11.2 deg. Results show the effect of protuberances representing a camera bump, an antenna, a reaction control system, and other appendages on the base cover pressure distribution. Comparisons with data from another test facility are also presented. (Author)


To the Editor: Gut microbiota, the trillions of microbes living in the human and rodent gut, play a pivotal role in cardiovascular diseases, including hypertension and atherosclerosis. One of the crucial mechanisms underlying gut microbiota functions in cardiovascular diseases is the microbiota-derived metabolites such as short-chain fatty acids (SCFAs). And emerging evidence demonstrated gut microbiota-derived metabolites –– SCFAs maintained stable blood pressure. However, there is no large cohort study on the correlation of SCFAs with hypertension.


The indications for transanal minimally invasive surgery (TAMIS) for the treatment of rectal adenomas are progressively broadening. Location in the upper rectum, a size of more than 5cm and a circumferential tumour involvement more than 50% of the rectal wall are no longer a contraindication. However, treating more difficult cases may lead to a higher risk of surgical complications. Peritoneal entry, detected during the procedure or in the postoperative period, has been reported quite frequently, especially for large anterior wall lesions of the upper rectum.


Lewy bodies, mainly composed of α‐synuclein (αS), are pathological hallmarks of Parkinson's disease and dementia with Lewy bodies. Epidemiological studies showed that green tea consumption or habitual intake of phenolic compounds reduced Parkinson's disease risk. We previously reported that phenolic compounds inhibited αS fibrillation and destabilized preformed αS fibrils. Cumulative evidence suggests that low‐order αS oligomers are neurotoxic and critical species in the pathogenesis of α‐synucleinopathies. To develop disease modifying therapies for α‐synucleinopathies, we examined effects of phenolic compounds (myricetin (Myr), curcumin, rosmarinic acid (RA), nordihydroguaiaretic acid, and ferulic acid) on αS oligomerization. Using methods such as photo‐induced cross‐linking of unmodified proteins, circular dichroism spectroscopy, the electron microscope, and the atomic force microscope, we showed that Myr and RA inhibited αS oligomerization and secondary structure conversion. The nuclear magnetic resonance analysis revealed that Myr directly bound to the N‐terminal region of αS, whereas direct binding of RA to monomeric αS was not detected. Electrophysiological assays for long‐term potentiation in mouse hippocampal slices revealed that Myr and RA ameliorated αS synaptic toxicity by inhibition of αS oligomerization. These results suggest that Myr and RA prevent the αS aggregation process, reducing the neurotoxicity of αS oligomers.


capital. It was allowed to borrow more widely, but never did so. It was always aimed largely though not exclusively at small and medium-sized businesses, to whom it lent on medium term, and generally on the security of fixed assets; by statute, its power to make larger loans was not unlimited, and although it could provide equity capital and offer guarantees it did very little of either. During its lifetime, before the Canadian government transformed it to the Federal Business Development bank in 1975, it made 65,000 loans, extended guarantees, and made 81 transactions that involved equity participation. Originally limited to the financing of industry, it experienced a gradual widening of lending powers, partly because of political pressure and partly because narrow rules created appalling problems with respect to the assessment of "eligibility," so that in and after 1961 it could lend to almost any sector of the economy. The author of this official history, who worked with the IDB for thirty years and who retired as the chief general manager of its successor, tells a thought-provoking tale. His attention is properly concentrated on the bank as an institution, but he links the story of internal evolution with larger developments, especially with those in the fields of politics and finance. When the bank was set up there was believed to be no source from which small and medium-sized businesses could borrow on medium term. But in the first fifteen years of the bank's existence there were parallel developments not only in the public sector but in the private: Canada's chartered banks began to make such loans, sales-finance companies became active in the same field, specialized private companies were formed, provincial governments, and even the national government itself, set up various agencies to nurture small enterprise. Meanwhile, the political agenda was broadening, as governments became anxious to help business, encourage Canadian ownership of firms, speed regional development, erase regional inequalities—goals which had certainly not been present in 1944, but which spurred the national government to effect the transformation of 1975. The IDB was always a minnow in Canada's financial ocean: even in 1975, its loans were only 5.2 percent of chartered-bank business loans. Its officers would have been quite happy to be left alone, assessing risks and financing worthwhile projects on the basis of its statutory definition of function and responsibility, thus paying no attention to these larger national purposes. It valued its independence and freedom from political manipulation, sheltered as it was behind the skirts of the central bank, from whom it borrowed at rates equal to or only slightly higher than the rates at which the national government could borrow. It always made a modest profit, although an element of subsidy was certainly implicit in that it almost never made a "normal return on equity capital." Supposed to lend on ventures that would succeed, it valued its ability to assess prospects, and was pleased that, in its final five years, 90 percent of its loans were classed as "satisfactory." But after nearly thirty years of genuine autonomy, it found in 1973/75 that Canada's government had larger plans. This book prompts one to reflect upon the interconnections among branch banking, administrative practices within banks, lending patterns, and statutory authority; it also contains plentiful examples of politicians' ignorance and confusion. Financial historians should certainly reflect upon the interconnections, while Clark can teach theorists of democracy a great deal about the relations between politicians, parliaments, and government businesses. It is fortunate, therefore, that Clark's exposition is so clear and occasionally so witty. His book deserves to be read outside Canada's borders.


Orthographic effects in spoken word recognition and phonological effects in visual word recognition have been observed in a variety of behavioral experimental paradigms, strongly suggesting that a close interrelationship exists between phonology and orthography. However, the metrics used to investigate these effects, such as consistency and neighborhood size, fail to generalize to words of various lengths or syllable structures, and do not take into account the more global similarity structure that exists between phonological and orthographic representations in the language. To address these limitations, the tools of Network Science were used to simultaneously characterize the phonological as well as orthographic similarity structure of words in English within a phonographic multiplex. In this paper, I analyze a section of the phonographic multiplex known as the phonographic network of language, where links are placed between words that are both phonologically and orthographically similar to each other, i.e., a link would be placed between words such as 'pant' (/p@nt/) and 'punt' (/p^nt/). Conventional psycholinguistic experiments (auditory naming and auditory lexical decision) and an archival analysis of the English Lexicon Project (visual naming and visual lexical decision) were conducted to investigate the influence of two network science metrics derived from the phonographic network—phonographic degree and phonographic clustering coefficient—on spoken and visual word recognition. Results indicated a facilitatory effect of phonographic degree on visual word recognition, and a facilitatory effect of phonographic clustering coefficient on spoken word recognition. The present findings have implications for theoretical models of spoken and visual word recognition, and for increasing our understanding of language learning and language disorders.


Atsushi Sawatari and Hiroshi Nakamura Laboratory of Cellulose Science and Technology, Department of Applied Biological Science Tokyo University of Agriculture and Technology, Fuchu-City, Tokyo, 183 Japan Abstract: The cellulose sheet surface with various durations of corona treatment were characterized by chemical modification in liquid phase-ESCA technique. Whatman #1 filter paper, regenerated cellulose film, handsheet from thermomechanical pulp (TMP), and handsheet from softwood bleached sulfate pulp (N-BKP) were used after washing with ethanol/benzene mixture. Carboxyl groups were found on the main chain of lignin on the surface of handsheet from TMP. However, no carboxyl groups were found on the main chain of the surface of the other cellulose sheets, namely, Whatman #1 filter paper, regenerated cellu lose film and handsheet from N-BKP. Carbonyl groups were introduced on the main chain of the surface of the all sheets used, after the treatment with corona discharge. Chemical modification-ESCA technique was very effective for the analysis of functional groups formed on the cellulose fibre sheet surfaces.


Abstract The redshift interval z = 2–3 is known as the cosmic noon that is the most active era of star formation across the Universe (Hopkins & Beacom 2006). In the past decade, many authors have investigated global properties of star-forming (SF) galaxies in this turbulent era, such as gas fractions and gaseous metallicities (e.g. Erb et al. 2006). With those achievements, we are going on to the next stage to understand more details i.e. those physical parameters in star-forming regions. Recent advent of near-infrared instruments typified by MOSFIRE on the Keck telescope, enable us with identifying the physical parameters of Hii regions in 'typical' SF galaxies individually (Steidel et al. 2014). Recent highlights suggest higher electron densities, higher ionization parameters, and harder UV radiation fields may be common. In order to know how galaxy evolution physically correlates with the natures of their star-forming regions, we have explored relationships between the electron density (ne ) of ionized gas from the oxygen line ratio and other physical properties, based on the deep spectra of Hα emitters at z = 2.5 by the MOSFIRE. MOSFIRE for the first time provides ne of the galaxies at high-z with a high level of confidence. The result shows the specific star formation rate (sSFR) and the SFR surface density (ΣSFR) are correlated with ne (Shimakawa et al. 2015). The ne -ΣSFR relation could be linked to the star formation law in Hii regions if we assume that hydrogen in Hii regions is fully-ionized. Otherwise, more active star formation per unit area (higher ΣSFRs), may cause higher ionization states. However, we need some specific concerns that obtained physical parameters should depend on the scale dependence, since typical size of Hii region is only <100 pc despite that we study physical states of entire galaxies. Thus we obtain surface-brightness-weighted and ensemble averaged line fluxes for the entire galaxy or the part that falls into the slit width (a few kpc scale size). The thirty meter telescope (TMT) is a powerful instrument to resolve such a difficulty, since its spatial resolution reaches <100 pc on the physical scale at z ~ 2 by AO assistance.


The purpose of the study was to evaluate the relationship between the provision of food to public primary schools by FTC and the enrolment of pupils in Mara Ward of Narok West Sub-County, Narok County, Kenya. The study adopted descriptive survey research design. The target population was 131 public primary schools in Narok West Sub-County, 1460 teachers and 3150 pupils. A sample of 97 schools, 302 teachers and 344 pupils was drawn. Simple random sampling method in the numbers of schools, teachers and pupils was used. Findings of the study showed that provision of food increased the enrolment rate of pupils in school. This is because meals programmes offered in schools enables the pupils from far and humble backgrounds to have similar treatment to the pupils coming from better backgrounds and close to the schools. These programmes increased the level of admission of new pupils thus increasing the rate of enrolment in most schools. However, offering food in schools does not automatically increase the rate of enrolment for it was realized that quality of food matters the most as well. The findings can help the government to sensitize on the quality of food being offered to be increased. Meals programmes should be implemented in all schools in Mara Ward and even to other parts of the country. In addition, the quality of the food offered should be increased to reduce diseases associated with malnutrition.


ABSTRACT This study presents the experimental investigation of half-scale, one-story, one-bay pinned frames equipped with a ribbed bracing system (RBS). The RBS is a newly developed passive control system designed to eliminate buckling and enhance the seismic behavior of structures. Here, mechanical models of this bracing system were designed and constructed. Pinned frames equipped with the RBS were cyclically tested. The hysteretic behavior and energy absorbing capacities of the frames were evaluated. Based on the results, the full plastic capacity of the brace was achieved and no buckling occurred. The RBS frame illustrated proper hysteretic behavior and energy dissipation capacity up to 4% story drift.


Existing road network evaluation methods have shortcomings in delineating the topology of the network. This paper uses a dual approach to analyze the topology of the road network. To use the approach, a stroke is introduced as the basis of the network and its abstracting principles are presented. Based on the principle of direction continuity, a program is designed to automatically decompose the road network into linear strokes. Then concentration degree is proposed as an indicator to quantify the centralization of a road network. Its calculation method is presented. Finally, an application demonstrates the use of the indicator. The results suggest its practical benefits to quantitatively evaluate a road network.


When assessing the information base of justice the capability approach focuses not just on people's actual achievements of well-being, but their freedom to achieve functionings. One of the advantages of this approach is that it allows us to widen the information base by adding a causal dimension to analyses of capability deficits. So starving can be distinguished from fasting by noting whether a person has the freedom to be malnourished. Including this information in justice and policy considerations allows us to redirect our attention and resources to individuals who lack freedom. Yet, although freedom has figured prominently in discussions of the approach, the sense in which an individual's personal responsibility for his or her disadvantage is relevant for questions of justice and equality has received relatively little attention. This is surprising given the prominent role the concept of responsibility has played in recent debates about justice and equality. But it is also surprising because theories of justice and equality typically accept that taking responsibility for the consequences of one's choices is a key criterion in deciding when to permit inequalities. In what follows, I will argue that the role the concept of responsibility should play in assessments of compensation and redistribution in a capability-based account of justice needs clarification. Further, that while a capability account must address the issue of responsibility in certain contexts, these are more limited than many liberals and supporters of the capability approach suggest. In section I, I will look at the role and scope of responsibility in recent debates in liberal political theory. In relation to the starving/fasting


In order to observe the tissue of rat's thyroid gland ,its mast cell's numbers and the dynamic changes on histechemical property, the sections of the rat's thyroid gland in different days were stained with H.E, toluidine blue(TB)and Alcian bluesafranin(ABS). The results showed that the diameter of thyroid gland fouicular enlarges(30?d,diameter is(383.90±52.79?)μm),the thyroid gland fouicular developed gradually to irregular form(55?d) and cell regiment(65?d). The numbers of mast cells increased gradually and were greater than controled ones(P0.01). The red or redblue granules of mast cell reduced gradually,while the blue ones increased gradually and their CEC value goes down.


Response surface methodology by Box-Behnken was applied to optimize the hot water extraction process of polysaccharides from Pleurotus ostreatus(POP).On the basis of one-factor experiments,the Design Expert 8.05b software was used to design the experiments and the response surface analysis of 3 factors was adopted.A second order quadratic equation for extraction of polysaccharides was built.After analyzed the significance of various factors and interactions,the optimal extraction conditions of the POP were concluded as follows: the ratio of material to water was 1∶44.6(g/ml),extraction temperature was 90℃,and extraction time was 4.3h.Under the optimal conditions,the yield of POP reached 3.25%.


The survival of very small fish can have a major impact on the dynamics of fisheries stocks. Numerous marking techniques have been developed or adapted to small fish in order to investigate either early life histories or small-sized species. Some techniques provide batch marks, while others provide individually unique identification with or without the need for destructive sampling. We review 20 marking techniques in the context of conducting survival studies for small fish, with examples focused on salmonid fry survival. Sixteen alternative release-recapture designs for conducting survival investigations are also examined. Eleven approaches are found capable of estimating survival parameters, while five are not. Of those methods capable of estimating fish survival, five require unique marks, and six permit batch-specific marks. No approach based on a single release of batch-marked fish is capable of statistically estimating survival. Investigators are encouraged to carefully coordinate their choice of marking technique with the design and analysis of the release-recapture model used.


The AMANDA neutrino detector has been in operation since the start of the austral winter of 1997. The analysis of the initial year of data taking has produced a 90% confidence level upper limit on an E−2 flux of muon-neutrinos, at the earth, at a level EΦ(E) = 8.4×10−7 cm−2 s−1 sr−1GeV, for a predominant neutrino energy range 6-1000 TeV, which is the most restrictive bound placed by any neutrino detector. When specific models of neutrino emission are tested, it is found that some are excluded. Here we summarise the findings of this first year of data taking, and discuss the prospects for diffuse neutrino searches with the expanded AMANDA-II detector.


ABSTRACT This study empirically examines the relationship between green supply chain management (GSCM) strategy and financial performance for shipping firms. We collect global data from 289 shipping firms and apply cluster analysis and analysis of variance (ANOVA) to test the research hypotheses. We cluster shipping firms according to their level of GSCM strategy adoption, which ranges from reactive to proactive. We find that shipping firms with a proactive GSCM strategy perform better financially. The findings of this study can contribute to shipping firms' environmental management strategy decisions and help tackle environmental problems while improving their financial outcome. This paper provides a discussion of managerial and theoretical implications and recommends future research directions.


This paper reviews the applications and potentials of back-wafer contacted silicon-on-glass (SOG) substrate-transfer technology (STT) particularly for RF and microwave silicon-device-design enhancement. This type of SOG process gives direct access to the part of the device that is usually connected via the bulk Si, by allowing advanced patterning and contacting of the backside of the wafer (back-wafer) with respect to the front of the wafer (front-wafer). In this manner the resistive and capacitive parasitics of the device itself, which in silicon often inhibit high-frequency (HF) performance, can be reduced to a minimum. At the same time new device concepts are made possible. Examples of fabricated devices (varactor diodes, vertical double-diffused MOSFETs (VDMOSFETs) and complementary bipolar transistors) are given and described in relationship to issues such as the very limited thermal budget permitted in the back-wafer processing and the inherently high thermal resistance of the SOG devices


This current study aims at describing the implementation of Genre-based
Approach at SMA Muhammdiyah 1 Klaten. The objective of this current study is
know the teaching learning process at SMA Muhammadiyah 1 Klaten using
Genre-based Approach. In this study, the writer uses an ethnographic research
which describes the implementation of Genre-based Approach in teaching
English. The methods of collecting data are observation, interview and
documentation. The procedures for analyzing data are reducing, display and
verifying. The result of this research shows the objective of learning, the model of
syllabus, the material of English teaching, the classroom procedure, classroom
activities in every stage, and problem faced by the teacher. The writer finds that
classroom procedure uses two procedures namely BKOF-MOT- JCOT-ICOT
BKOF-MOT-ICOT. In every stage there are many activities. The activities in
BKOF are asking question and giving explanation. In MOT the teacher gives
example of the text. In JCOT, the activity is the teacher makes a group. And
activities in ICOT are giving the task in the classroom and giving the task as
homework. The research also shows the problems faced by the teacher, namely
difficulty in managing the class, the students' limited vocabulary and students'
difficulty in writing coherence text. Genre-based Approach makes the teacher
easier to deliver the material. The implementation of Genre-based Approach
which is used by the teacher does not always use the stages of Genre-based
Approach.


This guide is intended to give instruction to online English 102 students for the Genocide in World War II annotated bibliography assignment.


Previous reports by Rosenzweig & Morosin [Acta Cryst. (1966). 20, 758–761], Liminga & Abrahams [J. Appl. Cryst. (1976). 9, 42–47] and Svensson, Albertsson, Liminga, Kvick & Abrahams [J. Chem. Phys. (1983). 78, 7343–7352], that the more steeply pointed ends of α-LiIO3 crystals grown from aqueous solution with 3 ≤ pH ≤ 7 have the apex of each pyramidal IO−3 ion pointing toward the direction which develops a positive polarity (d33 > 0) under tensile stress applied along the polar hexagonal axis, have been confirmed contrary to the conclusion of Yang Hua-guang, Zhang Dao-fan, Chen Wan-chun & Li Yin-yuan [J. Appl. Cryst.(1989). 22, 144–149]. The error leading to the latter conclusion is identified.


Digitisation of cultural heritage held by museums in Poland has been ongoing for several years. The process faces many obstacles, but some collections have been digitised and are available online, for example through Europeana and the Google Art Project. However, the majority of digitised objects are still unavailable through the Internet. The National Institute for Museums and Public Collections (Narodowy Instytut Muzealnictwa i Ochrony Zbiorow, NIMOZ, http://www.nimoz.pl) the state agency under the Ministry of Culture and National Heritage of Poland has been put in charge, among others, of digitisation of museum collections in Poland, as well as setting standards for collection management. NIMOZ has proposed a new E-Museums Project. The project aims to contribute to the development of the information society by facilitating access to Polish cultural heritage. The main objectives of the project are: (1) to improve access to cultural heritage housed in Polish museums, (2) to improve collection documentati...


This concluding chapter explores how multiculturalism has been understood and deployed, both within Hawaiʻi as well as the rest of the United States. In whatever form it takes, multiculturalism is a fundamentally unstable and conflicted concept. Distilled to its most basic elements, it poses a challenge to any kind of universalism that purports to speak for all members of a heterogeneous community. At the same time, however, multiculturalism is often seen as a means of accommodating difference within a defined community or political structure, be it a nation, city, or university. It is this tension, between universalism and particularism, that animates multiculturalist discourse, evoking the dilemma between national consensus and respect for minority opinion that is a defining feature of American democracy. But the lauding of minority perspectives that multiculturalism entails has been less a solution to the problem of social difference than an indirect acknowledgment of it.


Abstract. Hyperspectral imagery denoising is a classical problem in hyperspectral remote sensing applications. In our previous work, we combined principal component analysis with wavelet shrinkage, and good denoising results were obtained. We combine minimum noise fraction (MNF) with video block matching and 3D filtering (VBM3D), which is a powerful video denoising method. After MNF transform, we automatically select k0, the number of spectral band images as a threshold for denoising. We reduce the noise in spectral band images of MNF transformed data from k0 to the last band image and do not denoise the first k0  −  1 spectral band images. Finally, we perform an inverse MNF transform to obtain the denoised data cubes. We compare our MNF + VBM3D method with different denoising methods such as bivariate wavelet shrinkage (BivShrink), non-local means, SURELET, and block matching and 3D filtering (BM3D). Experimental results demonstrate that MNF + VBM3D achieves the best denoising results among almost all methods for three testing data cubes and with different noise levels.


The electrode performance of solid oxide fuel cells (SOFCs) strongly depends on their microstructural characteristics, such as the porosity, percolated paths of ionically and electronically conductive phases and in particular, the grain size. Deploying alternative manufacturing techniques, such as magnetron sputtering, that deposits nanostructured materials results in finer particle sizes and thus, increases the quantity of triple-phase boundaries in the anode functional layer (AFL) for SOFCs. Nanostructured NiO-YSZ thin films have been previously produced by reactive pulsed DC magnetron co-sputtering of metallic targets of zirconium-yttrium and nickel, defining the optimal deposition parameters to create state-of-the-art AFLs. Based on recent studies 1–3, the future of oxide-based anode materials for SOFCs will greatly focus on advancing the electrocatalyst through alternative non-precious metal doping and increasing the cell performance by tailoring the microstructure of the AFL. Therefore, in this study, vanadium oxides were doped into SOFC anodes using different concentrations to study their influence on the structural and morphological properties of magnetron-sputtered AFLs.


Deep-sea ecosystems cover about 65% of the Earth's surface and play an important part in biomass production and biogeochemical cycles on a global scale. These processes are largely mediated by benthic prokaryotes which use organic detritus for biomass production and respiration. Therefore marine sediments are configured as important biological matrix and play a prominent role in the ecology of the system of the deep sea. Events that occur in this compartment as organic matter degradation profoundly affect the chemical composition of the ocean and atmosphere in geological time. Due to its importance and complexity, the system of deep sea and its associated microorganisms have been the object of numerous studies in the last 50 years, especially in the last decade. Bacterial abundance, biomass and metabolic activity are the parameters most commonly measured in the sediments. Several methodologies can be used in microbial activity analysis of sediments, including the amino acids labeled with 14 C or ³H incorporation and the measurement of bacterial respiration. The biomass analysis often requires previous determination of bacterial abundance making it imperative that the quantification of sediment microorganisms is performed correctly. The separation of cells from sediment particles and their proper detachment are necessary for epifluorescence microscopy applications and flow cytometry analysis. The optimal use of extraction and analysis techniques and combined evaluation with other microbial parameters enable a greater understanding of the role played by prokaryotic organisms in world oceans.


(57) Abstract: The invention relates to a method and apparatus for monitoring the quality of the yarn. To more effectively separate the foreign substances contained in part of the yarn from the yarn itself or other foreign matter, the signal from the thread (8) (10) is classified in the classification field (16). Based on the classification result, foreign matter and the type contained in the yarn can be determined.


Objective To investigate the correlation between nocturnal acid break-through(NAB) and acid exposure in lower esophagus. Methods Totally 61 patients with duodenal ulcer confirmed by gastroscopy received omeprazole(20 mg twice a day) for 5 days.Ambulatory 24-hour intragastric and esophageal pH monitoring was performed on day 5.The relationship between nocturnal intragastric pH and lower esophagus pH was analyzed using equation of monovariate linear regression.Patients were divided into NAB group and non-NAB group,and the mean lower esophageal nocturnal pH and the mean nocturnal percentage of time of pH4 in lower esophagus were compared. Results The regression equation between the mean lower esophageal nocturnal pH and that of intragastric pH was as follows:y=4.054+0.288x.The regression equation between lower esophageal nocturnal percentage of time of pH4 and that of intragastric pH was as follows:y=5.780+0.204x.The mean lower esophageal nocturnal pH in the NAB group and non-NAB group was(5.31±0.89)and(5.92±0.99),respectively(P0.05).The mean nocturnal percentage of time of pH4 in lower esophageal in the NAB group and non-NAB group was 39.30% and 26.32%,respectively(P0.05). Conclusion The mean lower esophageal nocturnal pH and the lower esophageal nocturnal percentage of time of pH4 change along with those of intragastric pH.The acid exposure of lower esophagus increases in patients experience NAB when receiving proton pump inhibitor treatment.


The electric currents in the solar wind are described for the particular case of Parker's model, in which the sun's magnetic field is a dipole located at the center of the sun and inclined at an arbitrary angle to the sun's axis of rotation. The current consists of two components. The density of one depends only upon the sun's dipole moment, and that of the other depends upon the solar wind velocity and the sun's angular velocity as well as its dipole moment. The latter component flows in heliographic meridional planes. The electromagnetic forces of this component tend to accelerate the plasma in the leading half of a magnetic sector and to decelerate it in the following half. If the angle λ between the sun's spin axis and the dipole axis is different from either 0° or 90°, the electromagnetic force near the equatorial plane has a southward component in the positive sector and a northward component in the negative sector. The generalization to a more complicated solar magnetic field is discussed. The electromagnetic torque on the sun slows its rotation and for λ ≠ 0° or 90° also has oscillating components in the two directions perpendicular to the spin axis. These components tend to increase λ, indicating that the stable configuration is λ = 90°. For a given dipole moment, λ = 90° is also the orientation that maximizes the electromagnetic braking. Possible electromagnetic contributions to the sun's differential rotation are also considered.


There is an increasing interest in indoor occupation and guidance information for business and societal purposes Scientific literature has paid attention to various ways of detecting occupation using different sensors as data source including various algorithms for estimating occupation rates from this data Gaining meaningful insights from the data still faces challenges because the potential benefits are not well understood This study presents a proof-of-concept of an indoor occupation information system, following the design science methodology We review various types of sensor data that are typically available or easy-to-install in buildings such as offices, classrooms and meeting rooms This study contributes to current research by incorporating business requirements taken from expert interviews and tackling one of the main barriers for business by designing an affordable system on a common existing infrastructure We believe that occupation information systems call for further research, in particular also in the context of social distancing because of covid19 © Proceedings of the 13th IADIS International Conference ICT, Society and Human Beings 2020, ICT 2020 and Proceedings of the 6th IADIS International Conference Connected Smart Cities 2020, CSC 2020 and Proceedings of the 17th IADIS International Conference Web Based Communities and Social Media 2020, WBC 2020 - Part of the 14th Multi Conference on Computer Science and Information Systems, MCCSIS 2020 All rights reserved


Oceanographic Processes of Coral Reefs, D. Suzuki The Place of Science and Technology in the Wise Management of the Great Barrier Reef, J. Baker Physics-Biology Links in the Great Barrier Reef, E. Wolanski Landcover and Water Quality in River Catchments of the Great Barrier Reef Marine Park, A.K.L. Johnson et al. Runoff of Terrestrial Sediment and Nutrients into the Great Barrier Reef World Heritage Area, M. Furnas and A. Mitchell Water Circulation in Mangroves, and Its Implications for Biodiversity, E. Wolanski et al. Muddy Coastal Waters and Depleted Mangrove Coastlines - Depleted Seagrass and Coral Reefs, N.C. Duke and E. Wolanski The Effects of Siltation on Tropical Coastal Ecosystems, M. Fortes Modeling and Visualizing Interactions Between Natural Disturbances and Eutrophication as Causes of Coral Reef Degradation, L.J. McCook et al. Biodiversity on the Great Barrier Reef: Large-Scale Patterns and Turbidity-Related Local Loss of Soft Coral Taxa, K. Fabricius and G. De'ath River Plume Dynamics in the Central Great Barrier Reef, B. King et al. Connectivity in the Great Barrier Reef World Heritage Area - An Overview of Pathways and Processes, M. Cappo and R. Kelley A Model of the Ecosystem, and Associated Penaeid Prawn Community in the Far Northern Great Barrier Reef, N.A. Gribble The Effects of Water Flow Around Coral Reefs on the Distribution of Pre-Settlement Fish (Great Barrier Reef, Australia) J.H. Carleton et al. Topographic Steering by Coral Reef Assemblages, S. Spagnol et al. Environmental Factors Influencing the Activity of Black Marlin, P. Speare and C.R. Steinberg Ocean Nutrients to Sediment Banks via Tidal Jets and Halimeda Meadows, E.A. Drew Climate Variability and Change on the Great Barrier Reef, J.M. Lough The Sea Surface Temperature Story on the Great Barrier Reef During the Coral Bleaching Event of 1998, W. Skirving and J. Guinotte The Challenges of Coral Reef Management in Indonesia, I.M. Dutton et al. Will the Great Barrier Reef Survive Human Impact? F. H. Talbot


In this thesis, we discuss theoretical properties of various Higgs sectors, and we analyze constraints from current experimental data, and then we study collider signatures in each Higgs sector. In Part I, we focus on the phenomenology of various extended Higgs sectors such as the two Higgs doublet model, the Higgs triplet model and Higgs sectors in supersymmetric standard models. In Part II, we discuss new physics models at the TeV scale, in which the Higgs sector is extended, and neutrino masses, dark matter and/or baryon asymmetry of the Universe can be explained.


Basic concepts.- Theoretical framework.- Antecedents and effects of logistics outsourcing performance.- Methodology and sample characteristics.- Construct operationalization.- Structural models.- Summary and results.


Dysbiosis is characterized by an alteration in quantity and quality of intestinal microbiota composition. In the presence of dysbiosis, enterocytes will have difficulty in maintaining the integrity of the mucosal barrier, leading to increased intestinal permeability. These events are recognised to be linked to several chronic diseases. One of the consequences of dysbiosis is the manifestation of small intestinal bacterial overgrowth (SIBO), which is associated to a variety of chronic diseases. Single food nutrients and bioactive molecules, food additives, pre- and probiotics, and different dietary patterns may change the composition of the intestinal microbiota. Low FODMAPs diet has been a reference in SIBO treatment. This chapter intends to describe how the intestinal microbiota, dysbiosis, and SIBO can be related; to define dysbiosis food and nutrients influence; and to offer some nutritional therapy strategies for applying the low FODMAPs protocol, enabling better adherence by patients in order to increase their wellbeing.


Calculating the eigenmodes and eigenfrequencies of a perfect electric conductor cavity is one of the classical problems in electromagnetics. When we use the electric field integral equation (EFIE) to solve the problem, we will get a nonlinear eigenvalue problem because the frequency is the argument of the exponential function of the free space Green's function. A nonlinear eigenvalue problem is usually not easy to solve. In this work, a simple and iterative method is proposed for the EFIE eigenvalue problem. By using the Lagrange interpolation of the Green's function, the nonlinear eigenvalue problem can be transformed to a polynomial eigenvalue problem, which is then rearranged to the generalized eigenvalue problem. By solving the generalized eigenvalue problem iteratively, the resonance frequencies and modes of a cavity can be obtained. The method is applicable to arbitrarily shaped cavities and the numerical computation is easy to carry out. For demonstrating the accuracy and the feasibility of the method, several numerical results are presented.


Two types of monosyllabic speech discrimination training and two types of meaningful disyllabic speech discrimination training were conducted in a man with chronic Wernicke's aphasia. The effects of training on speech discrimination ability and auditory comprehension were investigated. The patient was a 48-year-old, right-handed male who started training about 4 years after putaminal hemorrhage. The training comprised a daily home task for a total of about 4 months, and the training results were measured once a week by a speech, language hearing therapist. In the monosyllabic speech discrimination training, a significant increase was seen in speech discrimination ability both in training with and without using written characters. In the speech discrimination training with meaningful disyllabic words, a better effect of training was seen with a method using oral reading of Kanji characters compared with a method of listening to sounds and comparing them with written characters. In an investigation of the effect using a Test of Lexical Processing in Aphasia for auditory comprehension, no change was observed with monosyllabic speech discrimination training; however, a significant increase in the number of correct answers was observed with speech discrimination training using meaningful disyllabic words.


Sometimes, when it really matters, everything falls apart. A vivid example of this occurred during the 2011 Republican primary presidential debate when Texas governor Rick Perry, in explaining how, if he were elected, he would eliminate three government agencies, couldn't call to mind the phrase "the department of energy": "The third agency of government I would do away with," the Governor proclaimed, "the education, the uh, the commerce and let's see, I can't—the third one. I can't. Sorry. Oops." He curtailed his presidential campaign shortly after this. Though other explanations are possible, it seems that Perry's monumental choke was in part due to his heightened state of anxiety over how well he was going to be perceived; his worry apparently interfered with his ability to bring to mind a phrase which in some sense he knew very well—after all, he had been railing against the department of energy nearly every day during the months leading up to the debate. But how does anxiety cause a choke? 1 How does anxiety cause one to bungle an action that would otherwise be a piece of cake? No one fully knows the answer to this question, however, the psychologist Sian Beilock, theorizes that anxiety may lead to choking in public speaking when individuals try to bring into working memory information they should be able to say automatically. (See for example, Beilock, Kulp, Holt, & Carr, 2004; Beilock & Carr, 2005; Beilock & DeCaro, 2007.) In explaining Chief Justice John Robert's fumbling of Obama's presidential oath, Beilock tells us that "when the pressure was on, [Roberts] fumbled the well-learned set of lines likely because [he] was devoting too much working memory to monitoring the words he knew by heart" (p.


Summary By means of two group experiments, performed in seven laboratories and using six different modifications in the in sulin radioimmunoassay technique, it is shown that the use of standards diluted in human serum of low basal insulin concentration, instead of buffer, improves appreciably the interlaboratory precision. The causes lies perhaps in some serum factor, which could disturb some modifications of the radioimmunoassay more than others. There was no im provement of precision when the same insulin standard was used in all laboratories. Standard curves made up in diffe rent human fasting sera have a scatter only within the range of pipetting and counting error.


Compounds of LiFePO4-based materials with the addition of Li3V2(PO4)3 were simply prepared by a rheological phase reaction method. Differential scanning calorimetry, thermogravimetric analysis, X-ray diffraction, scanning electron microscopy, transmission electron microscopy, cyclic voltammetry, alternating current impedance, and charge−discharge cycles were used to evaluate the LiFePO4−Li3V2(PO4)3 compound powders. Phase analysis showed that no new phase formed in these compounds. The electronic conductivity and electrochemical performance of the LiFePO4-based compounds were improved by the addition of Li3V2(PO4)3 composites. High rate discharge capacity was developed for LiFePO4−Li3V2(PO4)3 as cathode material.


The purpose of this research was to investigate the students' speaking skill through British Parliamentary (BP) debate System. This observation was taken 18 Days which started from Thursday, 13th February to 12 March 2020. The Qualitative Research Method was used in this research. The subjects of this research chosen randomly were 8 student as the representative of students in the fourth semester of English education UMN Al Washliyah Medan Class A, academic year 2019-2020. The population from this research were the whole students in the 4th semester English Education Department Class A.Technique of collecting data used was the observation in which the students were observed during debate class by using observation sheet designed with theory of Finocchiaro in Armasita (2017) to know the ability that have been achieved by the students and all the data found from 8 subjects of research that have been analyzed by the researcher there were 4 indicators/elements, namely pronunciation, vocabulary, fluency and comprehension. After the research conducted, it was found that there were 3 students with the higher speaking skill, 4 students with the moderate speaking skill, and only one student categories as the unsatisfied speaking skill. Shortly, this finding of the research was appropriate with the assumption in this research that is debate is effective to increase the students' speaking skill.


The maintenance of optimal body temperatures has profound consequences on all aspects of ectotherms life history, like fitness and performance, and has been the subject of research for decades. In contrast, for reptiles, comparatively less is known on the potential effects of water balance on physiology, ecology and behaviour. In recent years, several recent studies are pointing out the importance of studying thermoregulation and water balance within the same framework. Here, we used a Mediterranean lizard, Psammodromus algirus, to investigate how field body temperature and water loss rates may vary among populations, between sexes and along an altitudinal gradient. We found little variation in field body temperatures among populations, while within each population, field body temperature may change daily, seasonally and differ between sexes. On the contrary, water loss rates decreased with elevation and showed no seasonal trend or difference between sexes. Microclimatic data indicated that highland lizards experienced more fluctuating conditions, a factor that may explain their lower water loss rates. Other factors, like inter-population differences in ectoparasite intensity, might also contribute in explaining the observed patterns. We present here the first data for a lacertid lizard on the inter-population variability and sexual difference in water loss rates and point out that water balance may play a fundamental role in regulating lizard activity during the hottest and driest period of the year.


A new serum cortisol assay was introduced on the Elecsys (Roche), a random access analyzer, with reportedly good performance in the low (nmol/L) concentration range (preliminary data provided by the manufacturer) and with low cross-reactivity with cortisone [0.3% at 2.7 μmol/L cortisone (package insert)]. This prompted us to evaluate the performance of this new assay for the measurement of salivary cortisol.

For this study, saliva samples were collected with a Salivette® (Sarstedt), with an insert containing a sterile polyester swab for collection of the saliva, yielding a clear and particle-free sample. The salivettes were used according to the instructions provided by the manufacturer. Samples collected this way are stable at room temperature for at least a week and, therefore, offer the opportunity to collect samples at home (1)(2). Salivettes containing saliva were centrifuged at 2000 g for 10 min, and the filtrates were stored frozen (−20 °C). Before analysis, the samples were thawed, mixed, and placed on the Elecsys analyzer without pretreatment.

The Roche cortisol assay is a competitive electrochemiluminescence immunoassay (ECLIA) that uses a sheep polyclonal antibody. Endogenous cortisol contained in the sample is liberated from …


The model of partially mobile adsorption on microporous solids has been formulated for the cases of energetically homo- and heterogeneous adsorbents. Ethane and xenon adsorption isotherms on various forms of zeolite have been described by relationships derived from the proposed adsorption model.


A new line of work demonstrates how differential privacy can be used as a mathematical tool for guaranteeing generalization in adaptive data analysis. Specifically, if a differentially private analysis is applied on a sample S of i.i.d. examples to select a low-sensitivity function f, then w.h.p. f(S) is close to its expectation, even though f is being chosen adaptively, i.e., based on the data.
Very recently, Steinke and Ullman observed that these generalization guarantees can be used for proving concentration bounds in the non-adaptive setting, where the low-sensitivity function is fixed beforehand. In particular, they obtain alternative proofs for classical concentration bounds for low-sensitivity functions, such as the Chernoff bound and McDiarmid's Inequality. In this work, we extend this connection between differential privacy and concentration bounds, and show that differential privacy can be used to prove concentration of high-sensitivity functions.


Shortly after the epidemic of acute respiratory disease appeared at Camp Jackson in September, 1918, 1,653 Porto Rican laborers arrived in camp direct from Porto Rico to be employed in the construction work incident to the enlargement of the cantonment. A large proportion of these men were poorly developed individuals, most of whom suffered from chronic hookworm infection as well as from other intestinal parasites. They appeared undernourished and were obviously underclad, with their Palm Beach suits and Panama hats, for the almost freezing nights of South Carolina in November and December. Soon after the arrival of these Porto Rican laborers, respiratory infections developed among them, and 1,003 were admitted to the base hospital with the diagnosis of influenza. Of these, 220 exhibited signs of complicating pneumonia, and sixty-seven died, a mortality of 30.4 per cent. During the height of the epidemic, it became impossible to take cultures of the


The results of an exploratory study of UK organizations into methods for meeting project key performance indicators (KPIs) are presented. The paper explores: influences on the use of methods to manage project KPIs; the need for and existence of methods; the factors that facilitate the meeting of the KPIs. It is concluded that the use of methods varies depending upon the perceived importance of the project, the type of project, the client-team relationship and whether an organization performance management system exists. With project management capability often decreasing, in part due to a failure to meet psychosocial project KPIs, a need for methods linked to the KPIs was identified. However, the study found relatively low levels of adoption of such methods. Where psychosocial project KPIs were being met the following facilitating factors emerged: top-level policies, organization-wide training, integration with existing management processes, building into project management system. Situations were found where decision-makers did not consider the psychosocial KPIs of programme and project managers. This was seen to contribute to a failure by organizations to manage necessary increases in their project management capability and to be acting as a possible barrier to long-term, sustainable improvements in performance.


Abstract. Abundant new material of articulated asteroids from the Taba Starfish Bed (Lower Cretaceous, Barremian) of the Agadir Basin, western Morocco, allows reappraisal of this important fauna, and the recognition, to date, of five taxa belonging to the Astropectinidae, Odontasteridae, Goniasterididae, Terminasteridae, and Asteriidae. Betelgeusia orientalis Blake and Reboul, 2011 is shown to be a junior synonym of Coulonia platyspina Hess and Blake, 1995, and Dipsacaster africanus Blake and Reboul, 2011 comprises material of C. platyspina and a new odontasterid, here described as Odontaster tabaensis n. sp. Alkaidia megaungula n. sp. is described and its ontogeny and affinities discussed. From this, it is concluded that the Terminasteridae, revised to include the genera Terminaster and Alkaidia, is sister taxon to the extant family Zoroasteridae, and both are placed in the suborder Zorocallina of the Forcipulatida. The Taba fauna is a representative of a distinctive Lower Cretaceous asteroid assemblage that existed in northern Tethys from the Barremian to the Cenomanian and is also well known from the Albian and lower Cenomanian of Texas.


A process for the production of methanol containing a hydrogen and carbon oxides synthesis gas, passing the synthesis gas through a first reactor in which a part of the carbon oxides is catalytically converted to methanol, wherein supplying the obtained synthesis gas and methanol vapor-containing mixture to a second reactor, in which a further part of the carbon oxides is reacted to form methanol, which is separated off methanol from the synthesis gas, is recycled synthesis gas back to the first reactor and passed by a part stream of the synthesis gas at the first reactor and is introduced into the second reactor, characterized in that that the guided past the first part of the reactor current is diverted from the recycled after separation of methanol synthesis gas.


This study examines the analysis of the composition of solid waste generated in Port Harcourt local government area of Rivers state, Nigeria. The study area which is in the state capital is a typical urban, industrial and commercial location of Rivers state, and has witnessed an increased influx of migrants in recent time. This has led to the increased consumption of goods and services, and the generation of unprecedented quantities of municipal solid waste. The purpose of this study is to determine the sources, types and composition of wastes generated from Port Harcourt L.G.A, in order to develop a sustainable waste management strategy for the area. The determination of the composition of unprocessed municipal solid waste during this study was done according to ASTM D5231 - 92(2008) Standard Test Method. This method involves the direct sampling of solid waste from specific sources, a labour-intensive manual process of sorting, classifying and weighing all items from each sampling unit and a detailed recording of the data. This study has evaluated the solid waste composition in five distinct communities in Port Harcourt Local Government area with a view of an integrated approach in municipal solid waste management in the area. The generation rate was 1.16kg/cap/day. There was variance in the compositions of the waste from the different locations studied. The waste was categorized into Paper, Glass, metal, Organics, Nylon, Plastics, and Others. The most prominent in the five locations was Organics, Paper and Nylon with mean percentage compositions of 65%, 13% and 12% respectively. Given the characteristics of these waste streams, it is believed that a sustainable waste management strategy would be beneficial to the study area through better healthy living conditions, energy generation and resource recovery.


In this paper I examine factors that are
transforming the current patterns of forced migration into illegal
migration movements towards and within Europe causing enormous human suffering of the people on
the move. I critically assess the EU framing of extraterritoriality, border crisis and securi
ty and their
role in producing the notion of a so called 'refugee crisis' in Europe. The entry point of my discussion
is an interrogation of the prevalent notion of security within which the current migration patterns to the
so
-
called Global North are fram
ed, resulting in further hardening of the external borders of 'Fortress
Europe'. In doing so, I seek to reinstate the human security dimensions of this 'crisis' caused by the
ongoing processes of bordering and rebordering security. I argue that the concept
of human security has
to be at the centre of any discussions about security. To do so, it is critical to tackle the emerging global
social order characterised by unprecedented levels of inequality, causing global reproduction of
insecurity of peoples of t
he Global South as well as the Global North. This notion of security of peoples
cannot be pursued for one group at the expense of another. The concluding argument of this critical
analysis of the contemporary trends in framing migration in Europe, is that
there is an urgent need to
reconceptualise security and to link it to a model of mobility that recognises its global and systemic
character.


A theoretical framework useful for predicting the steady state response of enzyme-pH electrodes is developed. The model takes into account that the catalytic activity of the enzymes as well as the degree of dissociation of the product acids and bases is strongly dependent upon the local pH, and that buffering salts present in solution facilitate the transport of H+ ions. It is shown that the electrode should operate under substrate diffusion-limited conditions and the concentration of H+ ions should not have steep variations within the enzymic membrane. This condition can be fulfilled by adjusting the buffer concentration in the bulk solution. In the latter conditions the electrode response does not depend on the actual kinetics of the enzymic reaction, and can be predicted by an algebraic equation. The predictions are in excellent agreement with the experiments on penicillinase-pH and urease-pH electrodes.


Nonpuerperal uterine inversion is a rare condition. As nonpuerperal uterine inversion is rarely encountered by the gynecologist thus diagnosis and management could be challenging. We describe a case report of chronic inversion of nonpuerperal uterus secondary to submucous fibroid associated with severe anemia. A 45‑year‑old lady presented with menorrhagia and copious vaginal discharge followed by acute retention of urine. Diagnosis of partial inversion of the uterus was made, which was confirmed at laparotomy. Treatment of anemia was done and then she underwent abdominal hysterectomy with bilateral salpingo‑oophorectomy after correction of inversion.


The current light detection and ranging simultaneous localization and mapping (LiDAR-SLAM) system suffers greatly from low accuracy and limited robustness when faced with complicated circumstances. From our experiments, we find that current LiDAR-SLAM systems have limited performance when faced with specular surfaces such as glass, certain metals, and building walls that are rich in urban environments. Therefore, in this work, we propose a general LiDAR-SLAM system termed denoising and loop closure (DLC-SLAM) to tackle the problem of denoising and loop closure in complex environments with many noises and outliers caused by reflective materials. Current approaches for point cloud denoising are mainly designed for small-scale point clouds and cannot be extended to large-scale point cloud scenes. In this work, we first proposed a lightweight network for large-scale point cloud denoising. Subsequently, we have also designed an efficient loop closure network for place recognition in global optimization to improve the localization accuracy of the whole system. Finally, we demonstrated by extensive experiments and benchmark studies that our proposed LiDAR-SLAM system has a significant boost in localization accuracy when faced with noisy point clouds, with a marginal increase in the computational cost. Our systematical implementations are open-sourced to benefit the community.


The Internet of Vehicles (IoV) has emerged as a promising technology for transforming transportation systems by leveraging intelligent services and data-driven decision-making. Leveraging machine learning (ML) techniques, IoV data offers various benefits, including enhanced traffic management, improved road safety, and personalized user experiences. However, centralized ML methods face challenges in scalability and security, hampering their effectiveness in large-scale IoV deployments. This article presents a scalable and secure framework that incorporates distributed machine learning and blockchain technologies into the IoV ecosystem to overcome these limitations. The proposed framework enables the distribution of ML algorithms among participating vehicles, with each vehicle training a local model using its data. By executing a consensus algorithm, Roadside Units (RSUs) aggregate local models to provide more personalized and intelligent services in a scalable manner. Furthermore, the integration of blockchain ensures safety, transparency, and untampered features, thereby enhancing the overall security of the IoV system. This framework holds the potential to advance the efficiency, scalability, and security of IoV applications, paving the way for the widespread adoption of intelligent services in the transportation domain.


Installation practices are recommended that will increase rate of heat exchange between the thermometric sensing element and the cryogenic fluid and that will reduce the rate of undesired heat transfer to higher-temperature objects. Formulas and numerical data are given that help to estimate the magnitude of heat-conduction errors and of time lag in response.


A HOUSE of Lords report on whether England could cope with an epidemic says 'serious gaps in expertise' should be filled by nurses.


: Psychosocial repercussions of the COVID-19 pandemic may elevate individuals' vulnerability to suicidal behavior, creating new demands for psychotherapists, who have had to adapt to the online modality. Remote care for individuals and groups in urgency/emergency situations was considered inappropriate, but due to the pandemic this restriction was temporarily suspended. We designed a qualitative, exploratory study, based on Grounded Theory, with the objective of understanding the psychologists' perceptions about online care to patients with suicidal behavior during the pandemic. The initial sampling included 10 psychologists, in-depth interviews were conducted


The objective is to study of female consumers' perception regarding functional and psychological attributes govern a consumer's choice of an Apparel Retail Outlet. We also study reasons behind buying branded apparels. Toward this we first make specific research hypotheses based on the functional and psychological attributes. Next we describe the descriptive design used to test these hypotheses. Then we have used non probability convenience sampling method and the sample size taken is 134 female respondents. This project is about the female consumer behavior for organized apparel store and for this we have used the Questionnaire survey method for the research purpose. Then the results, based on analysis of data collected are presented. Finally, we conclude our objectives based on result of analysis.


Although much work has been done on seismic analysis for large span space lattice structures subjected to multi-dimensional multi-support excitations,its extreme value distribution of the stochastic response remains unaddressed.Analytical solutions can be obtained only in simple cases involving strong assumptions using the traditional level-crossing process theory;the diffusion process theory is just feasible for SDOF system.Based on this,the recently developed probability density evolution method is used to capture extreme value of large span space lattice structures subjected to multi-dimensional multi-support excitations.A virtual stochastic process is firstly constructed,then PDEM is built to evaluate extreme value distribution,and dynamic reliability of space structures can be obtained through simple integration.To verify the efficiency and accuracy of the introduced approach,the reliability and extreme value distribution of a long span single layer lattice shell structure under multi-dimensional multi-support excitations are observed.The results agree well with the ones obtained by the stochastic simulation method,so the introduced PDEM is of accuracy,efficiency and versatility.


The properties of bulk and adsorbed polyethylene-co-acrylic acid (PEA) random copolymers were characterized by solid-state NMR and vibrational spectroscopy. FTIR-PAS (Fourier transform infrared pho...


In the perioperatory is been high incidence to allergic reactions is about 1 in 20,000 patients already, this result by the simultaneous administration of the different medication in this period, some of this result highly allergiants. In this case presents a female patient 29 age, ASA I, pregnant 32 weeks, for non obstetric surgery, from the Emergency Unit, under general anesthesia, and present an allergic reaction, and was handle immediately with the steroids, epinephrine, and antihistaminic medications, obtain the quickly remission and there's no complication for the mother and the child in the future. Several allergic reaction in the perioperatory period are potentially the cause of many cardiovascular and pulmonary complications, including mortal and many of them occur unpredictability principal when the simultaneous administration of different medication occur as in a general anesthesia.


Equivalence class division is one of the typical test methods of black box.To divide all the data in the program to be tested into several parts and take from each part a few representative data as test sample can effectively reduce test times,improve software test effeciency and shorten software development cycle.


This is the tale of three young radiologists, Drs. Straw, Sticks, and Bricks, all nearing the end of their partnership tracks.


A Poincar\'e-covariant quark+diquark Faddeev equation is used to compute nucleon elastic form factors on $0\leq Q^2\leq 18 \,m_N^2$ ($m_N$ is the nucleon mass) and elucidate their role as probes of emergent hadronic mass in the Standard Model. The calculations expose features of the form factors that can be tested in new generation experiments at existing facilities, e.g. a zero in $G_E^p/G_M^p$; a maximum in $G_E^n/G_M^n$; and a zero in the proton's $d$-quark Dirac form factor, $F_1^d$. Additionally, examination of the associated light-front-transverse number and anomalous magnetisation densities reveals, inter alia: a marked excess of valence $u$-quarks in the neighbourhood of the proton's centre of transverse momentum; and that the valence $d$-quark is markedly more active magnetically than either of the valence $u$-quarks. The calculations and analysis also reveal other aspects of nucleon structure that could be tested with a high-luminosity accelerator capable of delivering higher beam energies than are currently available.


This study reports the synthesis of zirconia nanoparticles loaded on various carbon substrates, namely, reduced graphene oxide (Zr-r-GO), carbon nanotubes (Zr-CNT), and activated carbon (Zr-AC). In addition, a composite of zirconia–iron mixed oxide loaded on activated carbon (FeZr-AC) was also synthesized. The materials were characterized using SEM-EDX, HRTEM, FTIR, Raman spectroscopy, TGA and XRD. The FeZr-AC sample was found to have a nanorod like morphology. The samples were evaluated for their sensing potential towards methyl parathion (MP) using differential pulse voltammetry in a range of 0.0 V to −0.9 V (vs. Ag/AgCl) by drop casting on a glassy carbon electrode (GCE). All the modified GCEs best operated at a working potential of 0.4–0.9 V vs. Ag/AgCl/Cl−. FeZr-AC was found have the best limit of detection followed by Zr-AC, Zr-CNT and Zr-r-GO with their detection limits being 1.7 × 10−9 M, 17.2 ×10−9 M, 243.3 × 10−9 M and 534.0 × 10−9 M respectively. These materials were then used to detect MP in spiked sewage samples and showed good recoveries.


OBJECTIVES
The telomere (T) length, p21(WAF1/CIP1) and p27(Kip1) cyclin dependent kinase inhibitor (CDKI) genes are considered the markers of cell senescence and DNA damage. The aim of the study was to evaluate the influence of renal ischemia/reperfusion (I/R) on the value of above-mentioned markers.

METHODS
13 Macaque cynomolgus monkey kidneys were harvested and placed in Eurocollins solution. 9 kidneys were ex-vivo perfused with human blood and 4 kidneys were not perfused at all (control group). Tissue expression of p21(WAF1/CIP1) and p27(Kip1) was evaluated immunohistochemically and the T lengths were measured by southern blotting technique.

RESULTS
Significantly higher levels of p21 and p27 were expressed by the glomeruli (p = 0.001 and 0.0001), tubules (p = 0.0065 and 0.0006) and interstitial cells (p = 0.0017 and 0.0022, respectively) of the xenoperfused kidneys. The mean T length was higher in the control group (5.56 +/- 0.60 kbp) than in the study group kidneys (5.46 +/- 0.36 kbp) (P = NS).

CONCLUSION
Renal I/R is associated with telomere shortening and an over-expression of p21 and p27 genes indicating substantial DNA damage and/or accelerated tissue senescence.


The stability of thermohaline convection problems of Veronis and Stern types for stationary convection is studied for quite general nature of boundaries. It is shown by means of an appropriately chosen linear transformation, that in case of stationary convection the equations describing the eigenvalue problem for thermohaline convection problems are identical to equations describing the eigenvalue problem for classical Benard convection problem. As a consequence, the values of the critical Rayleigh numbers for the onset of stationary convection in thermohaline convection problems are obtained. Also, necessary conditions for the validity of principle of exchange of stabilities for thermohaline convection problems are derived using variational principle.


The toxicity of benfuracarb and -cyhalothrin on oak longicorn beetle, Moechotypa diphysis was investigated in terms of residual effect and control efficacy in the field. Mycelial growth inhibition of Lentinula edodes was also investigated in the laboratory. Benfuracarb and -cyhalothrin showed 100% of control values and over 90% residual activities of benfuracarb and -cyhalothrin were continued for 15 and 20 days after treatment, respectively. Benfuracarb and -cyhalothrin did not affect the mycelial growth of L. edodes Imhyup 1 variety. These results indicate that benfuracarb and -cyhalothrin might be used for the control of M. diphysis adults in the field.


We successfully report the formation of poly(N-acylethylenimine)−γ-cyclodextrin inclusion compounds (PNAI-γ-CD ICs). The PNAI-γ-CD ICs were obtained by three techniques:  (a) the precipitation of γ-CD in the polymer solution and (b) and (c) the suspension of as-received cage structure γ-CD and γ-CDCS, with a preformed channel structure, respectively, in the polymer solutions. The PNAI-γ-CD ICs were characterized by solid-state FTIR, X-ray, NMR, DSC, and TGA observations. A 1H NMR study was performed in order to follow the kinetics of the inclusion process in solution. The time-dependent inclusion of PNAIs with different molecular weights by suspension of either as-received cage structure γ-CD or channel structure γ-CDCS in the PNAI solutions was monitored with 1H NMR. Acetone, a nonsolvent for γ-CD, was used as the solvent for the PNAI solutions. Some aspects regarding the role water plays in the polymer inclusion process are revealed from our temporal observations of the inclusion of PNAI guests into sol...


Recent days, medical data are stored in the cloud for easy access and sharing the data of patients between the health center for treatments. In such a situation, the data stored in the cloud should be of lesser size to accommodate more information. To perform this size reduction a compression process is implemented to reduce the data without loss of information.

This paper performs such an operation in two ways one is to fast routing operation in the DMFB approach and to perform the compression from the chip. To implement this compression process, the data obtained from the chip is converted into image and then Image compression is implemented using ring cross over based Genetic Algorithm. So, First of all 8x8 arrays biochip is implemented with the module of ring cross for efficient process of consumption in power and area. The process of the system is leads to manipulate and manage the droplets as per the function of Micro fluidic (MF). Also, for avoiding pin-actuation conflicts, optimization process is processed with the merging of corresponding pin actuation sequences in parallel process along with the control pins. It synchronized the length by the optimization process.

In this study, this suggested technique reduces the consumption of area, and power miserably. The simulation result shows the improvement in the static power, dynamic power and delay. With the help of this algorithm image compression is implemented. And also this genetic algorithm compression application is compared with wavelet compression for better results.


As  a  country,  Indonesia  has  the  so-called  border  states  of  Indonesia  as  its sovereign boundaries. Border is an area that is prone to conflict and allusionsand political security for neighboring countries. In last couple of years (2002 -2012) there were three boundary problems between Indonesia and Malaysia, the problems that led to tensions between the two countries. On the other hand,border issues between Indonesia and PNG that affect the bilateral relations of the  two  countries  are  not  well  recorded.  Historically,  OPM  separatist movements were once recorded to pose a threat to the security of Indonesia. Threats  are  increasing  especially  when  OPM  uses  cross-border  access  in  the Indonesia - PNG  borders. This  study  focuses  on  how  the  Indonesian  border policy posture seen from the border case of Indonesia - Papua New Guinea.


To bridge the gap between lab-based high-resolution X-ray tomography (micro-CT) and synchrotron-based micro-CT, lab-scale accelerator-based or Inverse Compton Scattering (ICS) X-ray sources are a promising technology. In the scope of a large-scale project funded by the European Regional Development Fund (Interreg Grensregio), a new ICS source dubbed Smart*Light is being developed at TU Eindhoven. In this work, we present the advantages of this source compared to existing systems and its potential in industrial X-ray CT.


For verification, the pantomimic production of the interviewed persons is of particular interest. When deceiving, the number of illustrative gestures and emblems that accompany human speech is reduced. Fear of exposure produces adaptive and resourceful gestures in motor production, which is aimed at satisfying the need for self-preservation and restoring mental homeostasis under stress. The team of authors classifies adaptive gestures as resource gestures in case of deliberate concealment of information. They include stroking and touching their own body. The authors analyse the ethological, psychological and anthropological aspects of the tactile kinesics of hominids, primates and Homo sapiens. The purpose of the work is a differentiated study of gestures-adapters in case of deliberate concealment of information from persons involved in the crime on the control questions of a structured survey conversation. The study involved 20 persons involved in sexual crimes against minors and 20 respondents aged 18 to 65 who were not involved in the crime. A comparative analysis revealed that rapport was quickly formed among uninvolved persons, emotional stress decreased, and the mechanism of psychological adaptation to the test was triggered. The persons involved dissociated from the verifier, their level of physiological stress increased, verbal and non-verbal "leaksˮ of information arose. Resource pantomime (trance gestures, manipulator gestures, self-cleansing gestures, grooming, adapter gestures) was observed in 95 % of the subjects. During deception, adapters were fixed in 40 % of horizontal and vertical strokes and 30 % of self-touches. Body movements were aimed at restoring mental homeostasis and self-regulation of neuropsychic stress and unconsciously reproduced the tactile contact of the mother-child dyad.


Improving employment quality should be the meaning of the college employment in new era.We should understand the meaning of employment quality correctly and by building a information platform,sticking to the two positions,adhering to three concepts and paying attention to four stages,we should enhance college students' ability to get employed from four aspects,namely the feasibility of career planning,the comprehensiveness of occupation choosing skills,the appropriateness of professional reserve and the adaptability of career enviornment.Promoting the improvement of employment quality is the root of colleges and universityes' employment work in new era.


Packaging (1) for a food product (50) comprising a tubular casing (2) provided with a pre spiral cut line (7) extending about a longitudinal axis (X) of the envelope (2) so as to progressively tear the envelope (2) from one end (5) thereof forming a band (8) to discover the food product (30) as and when it is consumed. precut blank (30) for producing such a package.


An interpolation formula for the coefficient of thermal conductivity valid in the entire region of temperature is derived for Fermi gases on the basis uf the general quantum· statistical expression in terms of the time-dependent correlation function. The formula for the conductivity gives the temperature dependence of 1/T in the extremely degenerate case, and leads to an expression similar to that of Uehling for the first correction due to the Fermi statistics in the slightly degenerate case, and to the Enskog·Chapman theory in the clas· sica! limit. The behavior of the conductivity in the strongly degenerate case is clarified by making use of the S·wave approximation. It is shown that the minimum of the conductivity occurs at the temperature 0.164 times as large as the. degeneracy temperature. The results of calculations are used to discuss the experiment by Anderson et al. on the liquid He3 by employing Landau's theory of Fermi liquid. If the effective mass and the degeneracy temperature are taken as m=2.34m0 and Tc=2.13°K, which are consistent with recent experiments on the specific heat and the mass density, then a good agreement is obtained oblow beaut 0.07°K by assuming a=3.43X1o-s em for the scattering amplitude describing the collision between quasi-particle~.


Catalyzed Esterification of sec-butyl propionate in semi batch reactor prefers to be solved by dynamic-nonlinear programming (NLP) based optimization for determining optimal temperature and feed flowrate trajectories. In this autocatalytic esterification process, there are contrary objective functions, i.e. maximum productivity and minimum process time. Simultaneous optimization of these objectives yields in a dynamic multi-objective optimization (DMOO) problem, which is characterized by a set of multiple solutions, known as non-dominated or Pareto solutions. In this work, a control vector parameterization (CVP) and non-dominated sorting genetic algorithm (NSGA-II) approach were used to generate the Pareto solutions for two objectives: maximize conversion and minimize process time. Each point of Pareto solutions consists of different optimal temperature reactor and feed rate profiles, which lead to a variation combination of conversion and process time. These solutions give multiple alternatives in evaluating the trade-offs and selecting the most suitable operating policy.


Our objective was to assess the impact of a two-year emotional working memory program on behavioral inhibition of obsessive-compulsive patients. Ninety-seven obsessive-compulsive patients, 40-80 years old, were in the Emotional Working Memory (EWM) group (n=57) and the Usual Tutorial (UT) group (n=40) with four evaluation moments. Intervention focused on emotional working memory and aimed to improve behavioral inhibition by Emotional Working Memory Training software. The results revealed the beneficial effects of emotional working memory training program, which improved in obsessive-compulsive patients. These findings suggest that behavioral inhibition can be improved.


Most part of the radiation theory has been developed in the frequency domain. There have been different researchers who worked on the antenna theory in the time domain in the past as well. The main question still is: how an antenna radiates? The radiation mechanism, near-field, and energy flow have been studied in the frequency domain for single frequency cases. One needs to study all the above for a wideband signal in the time domain. In the other hand, we need to understand the transient state of an antenna in the near and far zone. We also want to demonstrate the reactive energy density and the radiation power flow for a short pulse in the near zone as well.


The state of the art of the PCM's reveals enabled characteristics that opens the door for multiple heat transfer and storage phenomena. The PCM absorbs, stores, and releases the energy during its phase change thus it most widely helps in latent heat transfer techniques. Nowadays Nano-fluid and Nano-phase change materials are replacing the general phase change materials because of its high heat transfer and storage capability. Further, varieties of passive heat transfer techniques such as heat exchangers of shell/tube type of various patterns and geometries are utilized to optimize the thermal energy. The artificial neural network is embedded in the system to recognize the pattern for faster processing. In this article, the PCM heat storage and transfer techniques are critically reviewed in comparison with the Cylindrical and Rectangular/Square shells/tubes based on the effect of parameters such as solidification/melting performance, enthalpy, fluid flow pattern in the liquid molten state, types of PCM used, etc. The numerical/analytical and experimentation techniques are categorized based on the results of various researcher and conclusion is established.


Introduces the connotation,essence,fundamental mode,and development status at home and abroad of contract energy management.On the basis of analyzing the status of China's contract energy management mechanism implementation,proposed countermeasures and suggestions to solve the main obstacles,in order to provide a theoretical reference for China to continue the implementation of the energy-saving management mechanism.


Alekhya Mitta Brian R. Curtis Jessica A. Reese James N. George Department of Biostatistics & Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma Hematology-Oncology Section, Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center Oklahoma City, Oklahoma The Platelet and Neutrophil Immunology Laboratory, BloodCenter of Wisconsin, Milwaukee, Wisconsin


User preferences are dynamically changing due to a variety of factors. Therefore, how to effectively extract the user's current preferences and accurately predict subsequent user preferences is one of the keys to improving service recommendation. This paper proposes a deep learning-based user preference prediction method, which combines user dynamic preference extraction and preference prediction. Firstly, the time-series LDA model is used to extract the user dynamic preference, then the LSTM neural network method is used to predict the user's preference of next time slice based on the user dynamic preference sequence. Finally, services are recommended to users based on predicted preference. The experimental results on real-world dataset show that the prediction performance of Time-aware-gate LSTM is slightly better than traditional LSTM, and the recommendation performance of the recommendation algorithm that takes preference prediction into account is better than those without preference prediction.


Single mode oscillation of the TE CO2 laser which contained strong absorber (NH3) was attained at the line center with the injection technique, although the presence of the absorber strongly reduced the CO2 laser gain at the line center. As the pressure of the NH3 gas was increased, the delay time of the single mode oscillation was also increased. In the single mode TE CO2 laser pulse, a dip was observed. The dip is due to an increase of the absorption by NH3 and is interpreted in term of the two-photon process.


Dental pulp stem cells have many advantages: they are pluripotent, can be cryopreserved and stored for long periods without losing their capacities of multiplication and differentiation. The wisdom teeth or natal teeth extracted for medical reasons are an opportunity for everyone to maintain stem cells for use in autologous cell therapy. Biobanks authorized and specialized in the preparation and storage of pulp stem cells provide access to the future regenerative medicine.


The relationship between QM practices and performance is the core and hot topic of quality management research.This paper gives a review on the research progress and existing issues in the field of QM practices and performance from the following four respects: the relationship between infrastructure practices and performance,the relationship between core practices and performance,the effect of situation on QM practices,the mechanism of how QM practices lead to enhancement of firm performance.After that,the author offer suggestions for future research.


Currently the application of statistical methods in medical research papers has reached a higher level,but in practice the confusion between "significance of difference" and "significant difference" always exists.Statistical conclusion shows statistical significance or no statistical significance,and does not denote professional size of difference.Although the difference with statistical significance or no statistical significance was called significance or no significance,statistical significance or no statistical significance is not equivalent to Significant difference or no Significant difference.


We investigate processes of bedrock‐core bar and island development in a bedrock‐influenced anastomosed reach of the Sabie River, Kruger National Park, eastern South Africa. For sites subject to alluvial stripping during an extreme flood event (~4,470–5,630 m3 s−1) in 2012, preflood and postflood aerial photographs and LiDAR data, 2‐D morphodynamic simulations, and field observations reveal that the thickest surviving alluvial deposits tend to be located over bedrock topographic lows. At a simulated peak discharge (~4,500 m3 s−1), most sediment (sand, fine gravel) is mobile but localized deposition on bedrock topographic highs is possible. At lower simulated discharges (<1,000 m3 s−1), topographic highs are not submerged, and deposition occurs in lower elevation areas, particularly in areas disconnected from the main channels during falling stage. Field observations suggest that in addition to discharge, rainwash between floods may redistribute sediments from bedrock topographic highs to lower elevation areas, and also highlight the critical role of vegetation colonization in bar stability, and in trapping of additional sediment and organics. These findings challenge the assumptions of preferential deposition on topographic highs that underpin previous analyses of Kruger National Park river dynamics, and are synthesized in a new conceptual model that demonstrates how initial bedrock topographic lows become topographic highs (bedrock‐core bars and islands) in the latter stages of sediment accumulation. The model provides particular insight into the development of mixed bedrock‐alluvial anastomosing along the Kruger National Park rivers, but similar processes of bar/island development likely occur along numerous other bedrock‐influenced rivers across dryland southern Africa and farther afield.


Introduction: Oral health is suspected to be linked to heart disease since species of bacteria that cause periodontitis and dental caries have been found in the atherosclerotic plaque in arteries in the heart. Objectives: The aim of this study was to characterize the oral microbiome in patients with coronary artery disease (CAD) and in a patient with dental caries (DC) without any clinical symptoms of CAD. Methods: DNA was extracted from the oral swabs collected from the patients and sequencing was performed by next generation sequencing method using Illumina (MiSeq) platform. The resulting sequencing data set was analysed using QIIME. Results: A total of 31 phyla were found in all the samples. The predominant phylum found in both CAD and DC was Firmicutes (46.09% & 38.98%), Proteobacteria (17.73% & 9.79%), Fusobacteria (13.44% & 17.95%), Bacteroidetes (11.82% & 22.73%), Actinobacteria (8.33% & 7.71%) and TM7 (2.25% & 2.71%). We found a similarity in the bacterial diversity in the two groups of patients. Conclusion: A comparison of the oral microbiome in patients with CAD and DC shows a similarity in the composition of the oral microbiota with variations in the proportion of a few genera.


619 A57-YEAR-OLD WOMAN with a history of childhood radiation therapy to her neck for tonsillar enlargement underwent right upper parathyroid gland excision in 2003 for primary hyperparathyroidism. The left upper and lower parathyroid glands were found to be eutopic and of normal size. The right lower parathyroid gland was not identified. Postoperatively, the patient had persistent primary hyperparathyroidism and was referred for remedial parathyroid exploration. Preoperative imaging with a technetium Tc 99m sestamibi scan suggested uptake in the right lower thyroid region. This was corroborated by magnetic resonance imagine (MRI) and thyroid ultrasound, which showed a fully intrathyroidal hypervascular hypoechoic mass in the right inferior thyroid pole (Fig. 1A and 1B, arrow pointing to posterior margin). An ultrasound-guided fine-needle aspiration of the lesion revealed an intact parathyroid hormone (PTH) level of 2330 pg/mL, confirming the presence of parathyroid tissue within the thyroid lobe. Based on this finding, the patient underwent minimally invasive parathyroid surgery (1). Under cervical block anesthesia the inferior aspect of the right thyroid lobe was resected. A rapid intraoperative PTH assay indicated a 50% decrease in plasma PTH levels after resection (2). Pathologic examination of the gross specimen demonstrated a fully intrathyroidal parathyroid adenoma measuring 1.2 cm (Fig. 2, normal size 5–7 mm). Histologic examination of the mass demonstrated a hematoxylin-eosin stained parathyroid adenoma embedded within the right thyroid gland (Fig. 3). The patient was discharged home on the day of the surgery. Follow-up serum calcium and PTH levels were within normal limits at 9.8 mg/dL and 9 pg/mL, respectively. Most individuals have four parathyroid glands located in eutopic positions along the posterior surface of the thyroid gland. However, as a result of embryologic variance, parathyroid glands can localize anywhere between the angle of the jaw and the pericardium. Occasionally, a gland will become encased within the thyroid. Of the intrathyroidal parathyroid glands that have been reported, the vast majority span the thyroid capsule and are only partially intrathyroidal (3). Very rarely, the gland will become fully encased within the thyroid parenchyma. The detection of intrathryoidal parathyroid adenomas frequently involves several imaging techniques, including radionuclide imaging, highresolution ultrasonography, computed tomography, MRI, arteriography, and venous sampling. The novel use of the rapid PTH assay for an ultrasound-guided tissue fine-needle aspiration is described to localize an intrathyroidal parathyroid adenoma in preparation for reexploration subsequently performed using minimally invasive techniques.


This article consists of a collection of slides from the author's conference presentation on the market for wireless high definition audio visual systems (HD A/V) Some of the specific topics discussed include: the benefits of HD A/V systems; data rates; challenges and solutions for 60 Ghz operations; wireless video area network design; the features of SiBeam's uncompressedf 50 GHz wireless HD chipset; and new areas of technological development for HD wireless A/V transceivers.


If Chinese wants be more effctive,the teachers shuold pay more attention to the effectively design of Chinese work,let the students feel it is intresting of re-learning and original creation.They can utilize Role-play type,interesting debate type,harmonious family type,reading and writing combined type,accumulate explore type,independent menu type and other method to design Chinese work effectively,let the students maste the use rule of using language in the vast majority of Chinese practice.