Gender classification in social platforms and social media has become a relevant topic for the industry because of its impact in making decision process. Gender recognition in Twitter is a business intelligence tool focused on twitter data acquisition, analysis, and process, and it can be used in many ways to transform it into valuable business intelligence data. In this paper, a method for gender recognition in Twitter users is proposed. This method employs several features related to user profile picture, screen name and profile description. This method was evaluated in a dataset with 574 users acquired from Twitter API, these users are located in Aguascalientes City at Mexico and they were manually labelled. The experimental results show an accuracy of 89.5%


HRM, Human Resource Management is a Key element of the total management process, in any organisation — Business, Government or Non-profi t. The more competitive the environment, the more critical is HRM. In the 21st century, all organizations have to meet and exceed their respective stakeholders' expectations, in order to survive and grow. Success requires, in particular, productivity in the use of all resources; and innovation, for differentiation and competitive advantage. HR is the active resource which has to mobilize, develop and utilize all other passive resources, such as capital, materials, technology, etc. But, if the HR itself is undermanaged, in any organisation, the other resources cannot be well managed. So, HRM has to be transformed, so that the entire organisation can be transformed and reinvented, periodically.


Kings at Karnak : a study of the treatment of the monuments of royal predecessors in the early New Kingdom


Before 1945, Masuria was part of Germany and known primarily as the scene of the 1914 Battle of Tannenberg and as an attractive summer vacationland of numerous lakes, extensive forests, and villages of characteristic wooden houses. Since 1945, Masuria has belonged to Poland, where it is known as the scene of the 1410 Battle of Tannenberg/Grunwald, and as an attractive summer vacationland. To students of nationalism and national identity, however, Masuria is interesting primarily because its predominately Polish-speaking population seems to present the clearest and best-documented example anywhere in Europe of national identity developing counter to native language. Although most Masurians spoke Polish and lived adjacent to Poland, they gave every indication over quite a long period of time of voluntary and virtually unanimous identification with the Prusso-German state and nation. They did so at a time when most of the rest of eastern Europe was increasingly subject to the influence of ethnolinguistic nationalism and the rest of the German–Polish borderlands were witness to one of Europe's classic ethnic-national rivalries. (see Maps 1 and 2)


The implications of the COVID-2019 pandemic, the crisis it has generated and its serious effects on public health are explained in the social, political, economic and legal areas With regard to this aspect, the management of the of COVID-2019 crisis in Colombia is described, through the analysis of the actions of the public powers, in order to determine whether the Political Constitution has been interpreted in accordance with the democratic regime established The methodology consisted of a documentary inquiry into the actions of the political and jurisdictional bodies that have regulated the COVID-2019 social crisis © 2020, Universidad del Zulia All rights reserved


The first important question which confronts the teacher of an introductory course in philosophy is likely to be the question as to how he may best approach the subject of what philosophy is, how to approach it in such a way as to pique the curiosity and excite the interest of the student from the beginning. After considering this question many times, it has recently occurred to the present writer that it might be helpful to make this approach by way of a parable, an allegorical account of what seem to be the three basic human desires—the desire to live, the desire to enjoy life, and the desire to understand life. He accordingly offers this suggestion for whatever it may be worth, and presents the following little tale as at least one possible working-out of that suggestion.


Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA

Introduction

Foxp3+ regulatory T cells (Tregs) have been thought to have at least two subsets: natural Tregs (nTregs) and induced Tregs (iTregs). Recently, expression of the transcription factor Helios, a member of the Ikaros gene family, has been expected to be a molecular marker of nTregs, but this is still controversial. To date, several in vitro studies and animal model studies regarding Helios have been reported, but there has been no examination of the clinical impact of Helios expression on Tregs in patients with lung cancer to date.

Methods

A total of 45 non-small cell lung cancer (NSCLC) patients who underwent surgical resection and 19 advanced/recurrent NSCLC patients was evaluated. Peripheral blood mononuclear cells (PBMCs) taken from these patients were examined by flow-cytometry. Of these 45 patients, 18 who were evaluable for tumor tissue underwent immunohistochemical investigation for tumor-infiltrating lymphocytes.

Results

Helios-negative Tregs of CD4+ T cells were significantly higher not only in all cancer patients (2.4%), but also in stage IA patients (2.6%) as compared with normal controls (1.5%, p<0.001). Patients who had a lower level of Helios-negative Tregs in tumor-infiltrating lymphocytes had significantly longer survival (p = 0.038).

Discussion

Helios-negative Tregs may be involved in immune suppression, even in early-stage NSCLC. The frequency of Helios-negative Tregs could be a useful prognostic biomarker in patients with NSCLC. The biological functions of Helios-negative Tregs in immune suppression should be further examined.

| Baseline demographics |
||
| Characteristic | N (%) |
| Age (y) | |
| Mean±SD | 67±8 |
| Sex | |
| Female | 27 (42) |
| Male | 37 (58) |
| Pathological stage | |
| IA | 22 (34) |
| IB | 16 (25) |
| IIA | 4 (6) |
| IIB | 3 (5) |
| III | 0 (0) |
| IV (Recurrence included) | |
| Chemotherapy | |
| 1st-line | 6 (9) |
| 2nd-line | 6 (9) |
| 3rd or later-line | 7 (11) |
| Pathological classification | |
| Adenocarcinoma | 51 (80) |
| Squamous cell carcinoma | 10 (16) |
| Others | 3 (5) |
| EGFR mutation | |
| Positive | 22 (34) |
| Negative | 31 (48) |
| Unknown | 11 (17) |

Citation Format: Satoshi Muto, Yuki Owada, Takuya Inoue, Yuzuru Watanabe, Takumi Yamaura, Mitsuro Fukuhara, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Jun Osugi, Mika Hoshino, Mitsunori Higuchi, Hiroyuki Suzuki, Mitsukazu Gotoh. Clinical features of transcriptional factor Helios expression on regulatory T cells in patients with non-small cell lung cancer. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 1280. doi:10.1158/1538-7445.AM2015-1280


The aim of this study was to investigate the factors affecting the science success of eighth-grade students using the Ordinal Logistic Regression method. In this study, information collected from a total of 4224 students, 2202 (52.1%) male and 2022 (47.9%) female, who participated in the ABIDE 2016 application was used. The scores obtained from the science course of the students entering the ABIDE 2016 application were transformed into categorical ones according to the determined threshold values. In the analysis, the categorical science success score was used as the predicted variable, and 15 variables that were thought to affect science success were used as predictive variables. The data obtained later were examined by the Ordinal Logistic Regression method. As a result of the examination, the factors affecting science success were determined as peer bullying, perceived self-efficiency, value given to the course, parental attention, family pressure, father's educational status, mother's educational status, monthly income, having a computer or tablet, having a room of one's own, student's educational goal and participation in science support courses. The findings were found to be remarkably similar to those found in the literature. This indicates that the OLR method is quite effective in predicting training data. Such research is expected to be handled objectively and without bias.


The first Articles of the German basic law contain the so-called basic rights. As Art. 1 para. 3 states they bind the legislature, the executive and the judiciary and therefore all state authority as directly applicable law. At first glance this sounds familiar and very similar to the bill of rights respectively the first ten amendments to the United States Constitution. But a closer look reveals that the German approach–especially handling free speech issues- is in many ways different from the situation in the United States [1].


The recently introduced projection technique in the theory of alloys is used to develop in a simple way the cluster expansions of the self-energy for an arbitrary reference medium. Three choices of the reference medium, self-consistent and non-self-consistent, are considered and pair site approximations (PSA) are developed. It is shown that the 'optical theorem' of the self-energy can be used to prove that for these PSA the sign of the density of states is not guaranteed to be non-negative.


Many forecasts have been made during the ten years since depopulation began. Differing hypotheses notwithstanding, they all affirm that the general vector of Russia's demographic development in the twenty-first century is further population decline. According to the average estimate, in the next fifteen years alone the decline will add up to thirteen or fourteen million persons, or more than 9 percent of the 2000 level. The inevitable acceleration in population decline reflects the narrowing of the reproductive base (the number of people of reproductive age) and the increase in reproductive losses (the number of deaths) as a result of a rapid rise in the average age. This brings such negative consequences as a decline in the size of the working population, a drastic increase in the costs of providing social support to the nonworking population, loss of defense potential, and disruption of the geopolitical balance. Based on Russia's current condition, depopulation is quite likely to cause the social, economic, and political degradation of the country, reducing it to a second-rate power with a dying population.


Background Protein ranking is a fundamental task in structural biology. Most protein ranking methods rely on the pairwise comparison of proteins while neglecting the global manifold structure of the protein database. Recently, graph regularized ranking is proposed by exploiting the global structure of the graph defined by these pairwise similarities. However, the existing graph regularized ranking methods are very sensitive to the choices of graph model and parameters, which remains a tough problem. Results To solve this problem, we have developed Multiple Graph regularized Ranking algorithm MultiG-Rank. Instead of using a single graph to regularize the ranking scores, we approximate the intrinsic manifold of protein distribution by combining multiple initial graphs for the regularization. The graph weights are learned with ranking scores jointly and automatically, by minimizing an object function alternately in an iterative algorithm. Experimental results on the ASTRAL SCOP protein database demonstrate that MultiG-Rank achieves the better ranking performance comparing to both other single graph regularized ranking methods and pairwise similarity base ranking methods. Conclusion The problem of graph model and parameter selection in graph regularized protein ranking can be effectively solved by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graph to solving protein ranking applications.


The telecommunication industry in Kenya has greatly contributed to the growth of the country's economy with a contribution of 0.76% to the GDP and revenue of KES 173.6 billion in the year 2015; thus, registering a 6.9 per cent increase (Economic Survey, 2015). Thus, for several years running, the sector has emerged to be the leading source of government revenue especially through tax remittance (Gatobu & Maende, 2019). Focus leadership emerged of importance in the various departments such as marketing, procurement, marketing, research, and development. Regression analyzed results of the primary collected data revealed solid substantial correlation on company infrastructure, marketing, procurement, human resources, as well as company productivity. This study seems to have cast its net wide on all competitive strategies. Besides, infrastructure, marketing, procurement, Abstract The telecommunication industry in Kenya has greatly contributed to the growth of the country's economy with massive contribution of to the GDP and revenue of KES 173.6 billion in the year 2015; thus, registering a 6.9 per cent increase. Thus, for several years running, the sector has emerged to be the leading source of government revenue especially through tax remittance. Hence the current study sought to investigate the influence of cost leadership strategy on firm performance in telecommunication industry in Kenya. Descriptive research design was adopted and regression analysis analyzed the data. It was documented that focus strategy had significant influence on firm performance in telecommunication industries in Kenya.


This paper reports on an experiment which addresses subjects' perception of the effect on information value of the degree of uncertainty in the prior state probability distribution in a particular decision setting. As in the preceding paper (see Hilton, Swieringa, and Hoskin [1981]), we used an experimental setting which separates the processes of decision making and information evaluation.' The next section discusses briefly the concept of degree of uncertainty and its functional relationship with information value. The following sections describe our experiment, present the results obtained, and discuss some of their implications.


LAR-9 High-temperature X-ray diffraction experiments have provided confirming evidence regarding the origin of the metastable gamma phase and of the general features of the zirconium-hydrogen phase system a s presented in LAR-8. These experiments a l so showed that the reaction alpha t delta -. beta (the eutectoid reaction on heating) proceeds at an extraordinar i ly slow ra t e , although the r e v e r s e reaction proceeds so rapidly that beta phase cannot be retained to room tempera ture by quenching,, The sluggishness of the eutectoid reaction on heating has undoubtedly resul ted in erroneous int e r p r e tation of cer ta in physic a1 and mechanical proper t ies determined previously in this and other investigations a Determination of the mechanical propert ies of zirconium hydride containing various minor alloy additions is continuing. data a r e still quite sketchy, alloy additions of 5 a/o Sc o r 2. 2 a/o Cu show the most promise at this time. Although these .. . . ; . 14 0 !, 1 . . . I .. . . . UNIVERSITY OF DENVER


Abstract In the présent work a first attempt is made to assess discards for the commercial trawl fishery in Hellenic waters. Overall, on-board sampling was conducted on 16 commercial trawlers for a total of 128 fishing days on 16 trawlers, carried out in 32 trips in four fishing areas during two fishing seasons (autumn-winter 1993, spring 1994). Our results showed that discarding is important for the Hellenic commercial trawl fishery and could be as high as 45% of the total trawl catch. Discard rates varied between species, areas and seasons and were found to be positively related to tow duration.


Abstract Mesometeorological information obtained in several research projects in southern Europe has been used to analyze perceived changes in the western Mediterranean summer storm regime. A procedure was developed to disaggregate daily precipitation data into three main components: frontal precipitation, summer storms, and Mediterranean cyclogenesis. Working hypotheses were derived on the likely processes involved. The results indicate that the precipitation regime in this Mediterranean region is very sensitive to variations in surface airmass temperature and moisture. Land-use perturbations that accumulated over historical time and greatly accelerated in the last 30 yr may have induced changes from an open, monsoon-type regime with frequent summer storms over the mountains inland to one dominated by closed vertical recirculations where feedback mechanisms favor the loss of storms over the coastal mountains and additional heating of the sea surface temperature during summer. This, in turn, favors Medite...


Classical swine fever is one of the most important infectious diseases that endanger the health of pigs.It has such characteristics as acuteness,heat and high contact,causing great economic losses to the world pig industry.At present,the traditional vaccination is stil the main means to prevent classical swine fever.Although traditional vaccines(such as C-strain)play a huge role in the prevention and control of classical swine fever,some shortcomings exist,such as the inability to differentiate between wild-type and vaccinated animals and the immune failure of classical swine fever.Therefore,the development of a new type of vaccine against classical swine fever is of great significance.With the continuous development of molecular biology technology and recombinant DNA technology,the research on genetic engineering vaccines has been continuously deepened.Six kinds of new classical swine fever vaccines such as subunit vaccines,nucleic acid vaccines,recombinant live vaccine vectors,gene deletion vaccines,ful-length infectious cDNA marker vaccines and synthetic peptide vaccines have been developed.Compared with the traditional vaccine,the new vaccine is cheap,safe,efficient,easy to transport and save and could distinguish between wild-type virus infection and vaccine immunization.The authors review the research pro-


This Chapter first dwells on the multi-vocal and polyphonic nature of interactive narratives and questions how a non-linear vision of the world might change our understanding of it. The ontological opportunities of the digital shift are offered to storytellers as creative forces to start their future projects.
What sort of digital narratives can we build to embrace, and take a stand on the profound changes in our society? How is interactivity and agency the crucial tool for this new type of narratives?
The second part of the Chapter is more practical and enumerates a series of mind shifts that are necessary for linear storytellers when conceiving interactive projects. The methodology that is proposed draws on the WHAT IF IT process - an ideation methodology that was researched and developed by Sandra Gaudenzi in the last four years through the EU training programme IF Lab (Interactive Factual Lab).


A Powerformer can be connected directly to a grid without step-up transformers, with a novel structure. A two-dimensional (2-D), field-circuit coupling, time-stepped finite-element method is used to model and simulate saturated symmetrical and asymmetrical short-circuit test at no-load on the Powerformer. According to IEEE Std.-115-2002, the d-axis transient reactance and time-constants are calculated from three-phase short-circuit tests, while the negative-sequence reactance is derived from the line to line short-circuit test.


This paper develops a model to explain why both business angels and venture capitalists exist in the risk capital market. Venture capitalists should earn their opportunity costs while business angels need not. From this observation, we identify where business angels and venture capitalists have their distinctive competitive advantages in the venture capital market. Venture capitalists can be more competitive if the required size of investments and the possibilities of risk-reducing information production are larger. Business angels can be more competitive if the required size of investments and the possibilities of the investor's contributions are smaller.


Discovering and locating gamma-ray sources in the whole sky map is a declared target of the Fermi Gamma-ray Space Telescope collaboration. In this paper, we carry out an unsupervised analysis of the collection of high-energy photons accumulated by the Large Area Telescope, the principal instrument on board the Fermi spacecraft, over a period of around 7.5 years using a Bayesian mixture model. A fixed, though unknown, number of parametric components identify the extra-galactic emitting sources we are searching for, while a further component represents parametrically the diffuse gammaray background due to both, extra-galactic and galactic high-energy photon emission. We determine the number of sources, their coordinates on the map and their intensities. The model parameters are estimated using a reversible jump MCMC algorithm which implements four different types of moves. These allow us to explore the dimension of the parameter space. The possible transitions remove from or add a source to the model, while leaving the background component unchanged. We furthermore present an heuristic procedure, based on the posterior distribution of the mixture weights, to qualify the nature of each detected source.


Chili is a vegetable with a characteristic of high moisture content, so easily damaged, and short shelf life. Most Indonesian households prefer to consume red chilies in fresh form. So, specific treatment is required to ensure the quality and shelf life of fresh red chilies. The objective of this study was to analyze the quality of red chilies stored in modified cold storage with and without dissolved ozone solution treatment. Red chilies were stored in perforated polyethylene (PE) plastic at 8±2℃ and 89±2% relative humidity. Fresh red chilies were investigated for hardness, color, moisture content, vitamin C, and capsaicin after 0, 1, 2, 3, and 4 weeks of storage. The modified cold storage preserved fresh red chilies for three weeks without ozone treatment and four weeks with ozone treatment. The moisture and vitamin C content remained stable, but the color, hardness, and capsaicin content significantly decreased.  Keywords: Chilies freshness, red chili, ozone treatment, modified cold storage, shelf life


Basal glomerular membrane represents mechanical and electrical obstacle for passing of plasma proteins. In physiological conditions only plasma proteins of low molecule weight are completely filtered through basal membrane. Due to damages of basal glomerular membrane there is increase in filtration of plasma protein of middle and high molecular weight. Depending on etiology of proteinuria it can be prerenal, renal and postrenal. By analyzing albumin a1-microglobulin, immunoglobulin G and a2-macroglobulin, together with total protein in urine, it is possible to detect and differentiate causes of prerenal, glomerular, tubular and postrenal proteinuria. The adequate and early differentiation of proteinuria is of an immense diagnostic and therapeutic importance.


This thesis is directed at the derivation of several methodologies associated with the Airland Battle Research Model currently under development at the Naval Postgraduate School. Two systems are presented that derive aggregated distribution allocation plans involving enemy and friendly direct-fire weapon systems. A military tactical scenario is used to present and contrast both systems. Additionally, allocation and placement models for ground force maneuver units are presented. Specifically, these models demonstrate how military units are allocated and placed on a battlefield -by various levels of organization. The use of a transportation network illustrates implementation of the models.


Homodesmotic stabilization energies of XPhCOCl and XPhCO+ estimated at the B3LYP/6–311G** level of theory for eight para-substituted derivatives (X = H, Cl, F, OH, OCH3, NH2, NO2 and CH3) are good descriptors for changes of the π-electron delocalization parameters of the ring, measured by NICS and HOMA, and also for geometry parameters of COCl and CO+ groups. Good correlations are also found for atomic charges in these groups. Electron-donating substituents elongate the C—Cl bond dramatically and increase the negative charge at the Cl atom in the XPhCOCl molecule. Copyright © 2004 John Wiley & Sons, Ltd.


Objective To develop a micro-stress sensor measurement system for invisible aligner based on siliconon-insulator( SOI) piezoresistive stress sensor and to measure the force magnitude of the invisible aligner. Methods The micro-stress sensor force measurement system was designed and built for invisible aligner. The resistance difference of the 13 sensor rosettes in the chip was measured before and after wearing the invisible aligner. The stress was calculated and the inverse force size formulated and analyzed by using the finite element module to simulate the results. Results The pressure resistance of the 13 sensor rosettes on the chip was measured and the stress status and the force inverse were obtained. The reverse force was caculated by computer and finite element analysis software and verified by finite element simulation model. The results were basically consistent. Conclusion The micro-stress sensor measurement system for invisible aligner developed in this study could be used for caculating the external force the teeth receive.


This short paper considers some questions regarding constitutional interpretation. It is separated into two parts. First, the author examines some of the normative considerations for and against judges openly articulating and consistently applying all-embracing approaches to constitutional interpretation — a development that Justice Kirby has previously advocated. In this regard, the author also recounts a number of recent and historical examples of the, at times, seemingly inconsistent approaches applied in interpreting the Commonwealth Constitution . Secondly, the author turns to examine some of the alternative methods of constitutional interpretation. The author argues that a form of 'moderate originalism' is the most justified of these approaches. In this regard, the author draws on the contributions of various theorists, as well as responding to some recent criticisms made of originalism.


Specific heat curves for various pressures, in many correlated electron systems, have been seen to cross at a point. We analyze this behavior using the spin fluctuation theory. It is found that when the system is considered near a ferromagnetic instability, the curves cross at one point and for systems near an antiferromagnetic instability, they cross at two points. The crossing behavior is related to the crossover of these systems from quantum to classical fluctuation regimes.


The practices of violence increased in educational institutions life, although the local Government had been implementing the peace education and the integration of national character values in the curriculum. Post-conflict of Maluku, the presence of the NGO "Save the Children" judged to provide a positive impact for students and schools through the implementation of child-friendly school at numbers of targeted schools in the city of Ambon. This research aimed to know the influence of physical and psychological violence against the interest and attention in learning of elementary school students. Research data collected by observed learning activities in the classroom, interviewed the students, teachers and principals. Samples of the victims of violence are 100 students taken from eight elementary schools in Ambon. Data were analyzed using multiple regressions. The results showed regression equation of violence against interest is (Y=34.421 + 0.148X1 + 0.010X2), and violence against attention is (Y = 38.772 + 0.106X1 + 0.046X2). Meanwhile, the results of the t test on hypothesis showed that the physical and psychological violence did not significantly affect the interest and attention, which is a contrast with the results of previous studies conducted in the district of West Seram.


In this paper, a method for interrogation of Fibre Bragg Grating (FBG) and single mode-multimode-single mode (SMS) fiber for simultaneous measurement of temperature and strain using is proposed and demonstrated. A half etched FBG is deployed in the optical circuitry for sensitivity enhancement. The sensor exhibits the temperature and strain sensitivity of 20.2 pm/°C and 1.91 pm/με over the range of 20-200 °C and 100-2020 με respectively. The resolution for temperature and strain measurement is ±0.5 °C and ±12 με. The experimental results show that the sensor is able to measure strain and temperature simultaneously by sensitivity matrix with additional advantages such as simple structure, compact size, ease of fabrication, and low cost.


As a new biometric feature, gait brings new possibilities for personal recognition. At present, gait recognition methods mainly extract appearance features, but seldom use temporal information, such as the method based on gait energy images (GEI) to fuse gait sequence into one image. In order to mine the motion patterns contained in gait sequences, this paper proposes a model that can gradually fuse temporal features while extracting spatial features to achieve the spatiotemporal feature extraction: 1) the model mines temporal information by passing partial channels of feature maps and fusing features of adjacent frames; 2) the model adapts the part-based method to split feature map into several parts, which can refine the spatial features. Extensive experiments on the challenging datasets CASIA-B demonstrate the superiority and effectiveness of our proposed model.


Nucleation and Crystal Growth is a groundbreaking text thatoffers an overview and description of the processes and phenomena associated with metastability of solutions and melts. The author—a noted expert in the field—puts the emphasis on low-temperature solutions that are typically involved in crystallization in a wide range of industries. The text begins with a review of the basic knowledge of solutions and the fundamentals of crystallization processes. The author then explores topics related to the metastable state of solutions and melts from the standpoint of three-dimensional nucleation and crystal growth.


The Liquid Gold cases are an adaptation of the original Calambra Olive Oil cases (UVA-QA-0440 and UVA-QA-0442). This version has been written to support a modified classroom experience. The cases describe the start-up of Calambra, a company built to sell a premier brand of olive oil. Frank Lockfeld, the founder, has to determine how much olive oil to make for the second year's production. Unfortunately, he has to make this decision before learning the results of the first year's sales. Thus, there is enormous uncertainty around the decision. The A case (UVA-QA-0587) tells the start-up story and presents enough information for students to do a sensitivity analysis to decide which of the many uncertainties are most important. This leads to a discussion of tornado diagrams. The B case (UVA-QA-0588) provides information on those critical uncertainties. This leads to a class on spreadsheet modeling and simulation modeling, searching for an optimal order quantity, adjusting for risk, etc. It also enables a discussion of a key general business issue: the difference between make-to-order and make-to-inventory businesses and the fundamental flaw in most business plans that leads to gross overestimates of potential profitability. Excerpt UVA-QA-0588 Rev. May 23, 2010 LIQUID GOLD: CALAMBRA OLIVE OIL (B) You: Okay, the Tornado chart shows we need to think more about demand—particularly the 1994 demand, the sales price, and the broker discount. Let's talk about demand first. Do you mind if I tape our conversation? That way, I can review the tape and make sure I remember what you say. Frank: That's fine with me. Demand Assessment You: Great. Let's start with demand. Do you still think you will sell all of the 1993 oil? What are the chances of this? . . .


PURPOSE: A display device, a glasses device and a controlling method of depth is provided to set appropriate depth for user by controlling depth about one among multiple content views. CONSTITUTION: Signal processing units (120-1~120-n) comprise a video frame by processing multiple contents each. An output unit (140) outputs multiple content views by assembling the video frame of contents. A synchronization signal generator (150) produces a synchronization signal for synchronization of glasses device which is matched for the each content view. An interface unit (160) transmits the synchronization signal to the glasses device. If depth adjustment command about one among the contents views is inputted, a control unit (170) controls the depth about the content view by the control of the signal processing units. [Reference numerals] (110-1) Receiving unit 1; (110-2) Receiving unit 2; (110-n) Receiving unit n; (120-1) Signal processing unit 1; (120-2) Signal processing unit 2; (120-n) Signal processing unit n; (140) Output unit; (150) Synchronization signal generator; (160) Interface unit; (170) Control unit


Purpose
This study aims to examine the timing of corporate disclosure in the context of Georgia, an emerging market where a recent reform of corporate financial transparency mandated about 80,000 private sector entities to publicly disclose their annual financial statements.

Design/methodology/approach
The main analysis covers more than 4,000 large, medium, small and micro private sector entities, for which the data is obtained from the Ministry of Finance of Georgia. This paper builds an empirical model of logit/probit regression, with industry fixed and random effects to investigate the drivers of the corporate disclosure timing.

Findings
Findings suggest that the mean reporting time lag is 279 days after the fiscal year-end, that is nine days after the statutory deadline. Almost one-third (30%) of the entities miss the nine-month statutory deadline, while the timely filers almost unexceptionally file immediately before the deadline. Multivariate tests reveal that voluntarily filing entities completed the process significantly faster than those mandated to do so; audited financial statements take more time to be filed, whereas those with unqualified audit opinion or audited by large/international audit firms are filed faster than their counterparts. The author concludes that despite the overall high filing rates, the timing of corporate disclosure is not (yet) efficiently enforced in practice (but is progressing over time), whereas regulatory incentives prevail over market incentives among the timely filers.

Originality/value
To the best of the author's knowledge, this is the first study that explores corporate disclosure timing incentives in the context of Georgia. This study extends prior literature on the timing of financial information from an emerging country's private sector perspective, with juxtaposed market and regulatory incentives.


Firstly,the paper puts forward three principles of agent rules design by literature research and comparative research;Secondly,agent rules in the model of innovation resource distribution have been described by stimulus-response rules;Last but not least the basic formula of agent rules has been abstracted.


Many of today's preachers actually take surveys among the members of their congregations to find out what kind of sermons they want to hear. People typically respond, "We want to hear messages on "How To Be Happy"....."How to Be Successful".... "How to Be Prosperous,"........and "How To Overcome Bad Habits and Addictions." People want to be told that God loves them and will bless them no matter what lifestyle choices they make.


The possibility of an RF‐resonance polarimeter (RFP) for fast non‐destructive measurement of beam polarization in an accelerator ring is considered. In order to accumulate the spin‐dependent beam transition radiation, a passive superconducting cavity is proposed. The increase of effective voltage in the cavity (TM110 mode) with time, related to the free oscillating coherent spin of the beam, is calculated. The efficiency of the RFP does not decrease with particle energy and is proportional to the average beam current. Siberian snakes can be used in order to provide a sufficiently small value for the spin tune spread. Possible schemes of measurement of the accumulated voltage are presented. The noise limitations are taken into account and evaluated. There are in the RFP dynamics different effects of the beam charge ‐ cavity interaction, positive and negative. The negative effects are the beam noises, while the positive ones are as follows: ‐the possibility to enhance the spin‐dependent beam cavity interact...


Purpose – The enforcement of liquidated and ascertained damages (LADs) can be problematic when the amounts are poorly assessed and there are lapses in the administration of contracts. This paper seeks to investigate the relevance of LAD clauses in construction contracts in Ghana, as well as the methods employed in their assessment and enforcement.Design/methodology/approach – A parallel survey method was adopted. Three sets of similar questionnaires (slightly modified) were administered to professionals in client, consultant and contractor organisations in contract administration roles, to explore their experiences in the assessment and enforcement of LADs.Findings – LADs are not serving their purpose in construction contracts in Ghana. Clients have created situations that render LADs unenforceable. LAD amounts are also not genuine pre‐estimates of expected loss to be incurred, as assumptions and guesses rather than genuine calculations on a case‐by‐case basis are adopted in their assessment.Originality/v...


Objective: Lifestyle and environmental factors play an important role in the pathogenesis of hypertension. We aimed to compare the epidemiology of hypertension in Asian Indians from two different geographic regions (Singapore and rural India). We hypothesize that the prevalence would be higher but the awareness, treatment and control of hypertension would be better in Singapore Indians than in rural Indians. Methods: We analyzed data from large population-based studies: the Singapore Indian Eye Study (SINDI, n = 3,228, aged 40–80 years, 49.2% women) and the Central India Eye and Medical Study (CIEMS, n = 3,591, aged ≥40 years, 52.6% women). Hypertension was defined as systolic BP ≥140 or diastolic BP ≥90 mm Hg or self-reported history/treatment for hypertension. Results: The crude prevalence of hypertension was higher in SINDI (59.7%), compared to CIEMS (28.2%). In multivariable models adjusting for potential confounders, increasing age and overweight showed a positive and 'never drinking alcohol' showed a protective association with hypertension in both populations. Primary/lower education, hypercholesterolemia and diabetes in SINDI and being female in CIEMS showed a positive association. Among those with hypertension, 35.9% in SINDI and 25.3% in CIEMS were aware of their condition of which 83% in SINDI and. 32% in CIEMS were on treatment for hypertension. The BP control was similar between the two populations (45% in SINDI and 47% in CIEMS). Conclusions: The prevalence, awareness and treatment for hypertension were higher in Singapore Indians than in rural Indians and the risk factor associations (socioeconomic and metabolic) were different between the two populations.


The choice of camera and tube depended upon the consideration of criteria such as the dynamic range, linearity, uniformity of response, resolution, flare, persistence, spectral response and number of blemishes. A method of asessing the resolution of a television camera system which gave the modulation transter function (MTF) directly on an oscilloscope is described. The camera employed in this particular application was of the low light level type, the pictures being recorded on a video tape recorder (VTR) whose characteristics also had to be considered. A calibration grey scale was included in the picture by means of a split viewing arrangement. The fundamental feature of the video analysis system for deriving the luminance values was an analogue processor which gave the average video signal level over any selected area of the television picture. The accuracy of the system has been assessed for road luminance values measured from a mobile laboratory by comparing them with independent measurements using a Pritchard photometer.


M u sic educators have long recognized the use of musical creativity as an effective tool in teaching music knowledge and skills to young students. Inclusion of creativity in the K-12 music curricula across the country indicates the success of creative activity and the importance placed on creativity in the developing child. Because of the general recognition that creative involvement is an important learning and experiential tool for adults as well as children, insightful instructors often include creative activities involving improvisation and composition in private and class instrumental, vocal, and keyboard lessons for adults. Some materials provide excellent sequenced creative activities corresponding with the musical development of the adult student in those settings. A more challenging setting for providing successful creative ex-


A new analysis from RRI provides an unprecedented assessment of legal frameworks regarding indigenous and rural women's community forest rights in 30 developing countries comprising 78 percent of the developing world's forests.


NASA Glenn Research Center Cleveland, OH 44135 Although many methods are available for producing single-walled carbon nanotubes (SWNTs), the conventional carbon arc process remains the most popular due to its simplicity and large production rate. In the carbon arc, SWNTs are catalytically synthesized by rapidly evaporating a graphite anode impregnated with Ni/Y metal catalyst from which the nanotubes grow in an inert atmosphere. However, high temperatures inside the carbon arc generate strong buoyancy driven convection, and it is hypothesized that the non-uniform environment created by this flow has a large effect on the growth and morphology of the SWNTs. To study the effect of buoyancy on the arc process, a miniature carbon arc apparatus was developed to synthesize SWNTs in a microgravity environment substantially free from these strong convective flows. The reactor was operated for either 2.2- or 5-seconds during free-fall in the drop towers at the NASA Glenn Research Center. Two apparatus designs differing mainly in their production rate and power capacity were investigated. The first consisted of a miniaturized carbon arc employing a 1 mm diameter graphite anode and powered by a 0.54 F capacitor bank charged to 65 V. The second, larger apparatus employed a 4 mm diameter anode and was powered by a portable battery pack capable of providing in excess of 300 amps at 30 volts to the arc for the duration of a 5-second drop. Initial results indicated that transient heating is a very large effect in the short-duration drop tower carbon arcs, and thermal equilibrium of the arc plasma, buffer gas, and apparatus was not attained during the short microgravity periods. In addition, removal of the buoyant convection by the microgravity now allowed clear observation of large jets of evaporated carbon vapor streaming from the anode and mixing with the inert buffer gas. The initial mixing of these jets with the cold buffer gas combined with the thermal transient made it difficult to establish a uniform high temperature environment around the arc in the 2.1- to 5-second microgravity time interval, and even with a very high-powered arc, the arc region was cooler than in continuously operated arcs. Despite these difficulties, the miniature arc produced SWNTs in microgravity. However, given the large thermal transient to overcome, no dramatic difference in sample yield or composition was noted between normal gravity and 2.2- and 5-second long microgravity runs.


This article explores the level of influence of hardware virtualization on image processing efficiency, due to added software layer of a hypervisor. Paper takes the form of case study in which the capabilities of Agisoft PhotoScan's automatic bundle adjustment, are going to be evaluated in the aspect of processing time under various environment settings. All measurements will be performed using consumer grade hardware running GNU/Linux operating system together with most popular hypervisors for creating virtual machines. Also ownCloud instance will be used to simulate processing with cloud data access, along with its WebDAV interface. Data test field used to estimate processing efficiency contains block of 171 photographs arranged in 11 strips, acquired using DMC II 230 full-format aerial camera, yielding around 105GB of raw uncompressed image data.


In this paper a modern radar signal processing various stages have been studied. In modern radar sets the conversion of radar signals to digital form is typically accomplished after IF amplification and phase sensitive detection. The signal processor is that part of the system which separates targets from clutter on the basis of Doppler content and amplitude characteristics. All measures are referred to as radar signal processing and radar data processing that calculates from the received echo signal an evaluable image on the radar display. With radar signal processing is referred the part that is still dealing with the analogue (or often present even as a digital value) magnitude of the echo signal.


Volunteering enjoys the widespread support of all main UK political parties. As previous governments have done in the past, the Coalition government is attempting to implement policies aimed at encouraging and supporting greater levels of volunteering in the UK. Much volunteering policy has been directed at voluntary organisations, often through government funding. In this paper I consider the limits that policy directed at voluntary organisations has in encouraging volunteering. I highlight that a great deal of volunteering occurs informally (not through an organisation), in the public and private sectors, in small organisations below the radar of policy, and in organisations that do not rely on government funding. Furthermore, I suggest that the distinctive characteristics that the voluntary sector is celebrated for allows them to remain independent of government policies. To conclude I suggest that for volunteering policy to be effective, a greater understanding of volunteering that takes place informally and in small community organisations is needed, as well as a greater understanding of what shapes the volunteering strategies or approaches of organisations.


Chapter XVI: 2–57 of Vita Constantini-Cyrilli offers an unabridged translation of a lengthy passage from apostle Paul's First letter to the Corinthians (14: 5–9). The Old Church Slavonic translation closely follows the Byzantine redaction of the Greek original; 5 variants are found, which are not covered in the Nestle/ Aland edition of the New Testament. While the Old Church Slavonic translation is a good example for the Bible tanslations made by Cyrill and Method in preparation of their Moravian mission, it poses two questions. The first question is related to the condition, the text is preserved in the transmitted copies of Vita Cyrilli. Sometimes the correct Old Church Slavonic translation of the Greek source can only been reached by a re-combination of the extent reading variants from different manuscripts. It can be asked why no copyist of Vita Cyrilli bothered to compare the text, he was copying, with a sound Church Slavonic translation, which had been possible, at least, after the appearance of printed Slavonic Bibles. The second question is related to the function, the lengthy translation may have in the context of Vita Cyrilli. Being an example for the high quality of the first Slavic Bible translation of Cyrill and Method, it may have been included into Vita Cyrilli originally in company with the Greek original. Additionally, the topic of 'speech and language' seems related to the narrative context of Vita Cyrilli, where the Venetian clergy promotes the theory of "Holy three languages". The paper suggests, that the argument of "Holy three languages" has a more 'nationalistic' meaning here in comparison to Vita Cyrilli XV: 5, where the argument had already been used by the clergy of Salzburg.


We are part of a growing community of researchers who are developing a new class of soft machines. By using mechanically soft materials (MPa modulus) we can design systems which overcome the bulk-mechanical mismatches between soft biological systems and hard engineered components. To develop fully integrated soft machines—which include power, communications, and control sub-systems—the research community requires methods for interconnecting between soft and hard electronics. Sensors based upon eutectic gallium alloys in microfluidic channels can be used to measure normal and strain forces, but integrating these sensors into systems of heterogeneous Young's modulus is difficult due the complexity of finding a material which is electrically conductive, mechanically flexible, and stable over prolonged periods of time. Many existing gallium-based liquid alloy sensors are not mechanically or electrically robust, and have poor stability over time. We present the design and fabrication of a high-resolution pressure-sensor soft system that can transduce normal force into a digital output. In this soft system, which is built on a monolithic silicone substrate, a galinstan-based microfluidic pressure sensor is integrated with a flexible printed circuit board. We used conductive thread as the interconnect and found that this method alleviates problems arising due to the mechanical mismatch between conventional metal wires and soft or liquid materials. Conductive thread is low-cost, it is readily wetted by the liquid metal, it produces little bending moment into the microfluidic channel, and it can be connected directly onto the copper bond-pads of the flexible printed circuit board. We built a bridge-system to provide stable readings from the galinstan pressure sensor. This system gives linear measurement results between 500–3500 Pa of applied pressure. We anticipate that integrated systems of this type will find utility in soft-robotic systems as used for wearable technologies like virtual reality, or in soft-medical devices such as exoskeletal rehabilitation robots.


Objective To Investigate the effect of low molecular weight heparin (LMWH)on lipid metabolism in end - stage renal failure hemeodialysis patients. Methods Triglycerides (TG) and cholesterol (CH) lipoproteins and apolipoprotein of 18 hemeodialysis patients who used unfractionated heparin (UFH), and 16 patients who used (LMWH) was investigated by retrospective analysis. Results Compare with UFH, decrease of TG、Tch、LDL、Apo - B and increase of HDL was observed in LMWH group on 6 months and 12 months; compare with 0 months, decrease of TG、Tch、LDL、Apo - B and increase of HDL was observed on 6 months and 12 months in LMWH group and increase of Tch、LDL、Apo - B was observed on 12 months in of UFH group. Conclusion In hypertriglyc-eridaemic HD patients, LMWH improved metabolism of triglycerides and cholesterol lipoproteins and apolipoprotein.


Equations analogous to the Lyapunov matrix equation are derived for second-order n -dimensional systems. These are shown to be more readily solvable than the equivalent 2n -dimensional Lyapunov matrix equation.


Summary Humoral responses to ovalbumin (OA) administered i.p. with Al(OH)3‐were depressed in C57BL mice immunized 5–13 days after infection with N. dubius, but not N. brasiliensis or T. muris. These two parasites induced elevated IgM responses, possibly as a result of systemic contact with parasite larvae or debris since i.v. administered N. dubius also increased IgM titres to OA. Depression of anti‐OA IgG titres by N. dubius was also observed in infected BALB/c and CBA mice given OA‐Al(OH)3 (i.p.), but not in C57BL mice given OA‐Al(OH)3 (s.c), OA‐FCA (i.p. or s.c), or OA‐B. pertussis (i.p.). These findings suggest that local effects of N. dubius within the peritoneum reduce the adjuvanticity of Al(OH)3, resulting in depressed responses to OA‐Al(OH)3.


Woollen slubbings are the product of the woollen carding machine and are formed by a rubbing action after the carded web has been split into narrow ribbons of fibre in the condenser section of the machine. The individual effects of different rubbing settings on the strength of the slubbing are investigated, and the importance of the apron spacing between the two rubbing surfaces is highlighted. It is also indicated that higher slubbing strength is associated with increased yarn strength. Two novel methods of measuring the fibre orientation in the woollen slubbing are outlined, and it is shown that the fibre orientation in the woollen slubbing improves with increases in the rubbing frequency, stroke length and decreases in the apron spacing.


The eye is the window to the brain, the soul, and now perhaps even the future, with the exciting publication by Chowers et al in this month's issue of the BJO (p 991). The authors give us a view of the future as they elegantly demonstrate that gene transfer into blood vessels is possible in a rat model of retinopathy of prematurity (ROP). The future may be close at hand, because the eye once again offers an ideal organ to study the effects of this new therapy. ROP, a developmental disease of retinal angiogenesis in premature infants, is also an optimal and important disease to study potential therapeutic effects of gene therapy.

To date, the view of future gene therapy has been through hazy media at best. Despite incredible advances in developmental biology and molecular genetics during the past several decades, efforts to utilise these advances, and to deliver therapeutic genes to target organs or structures, have often been disappointing. The reason for disappointment usually hinges on delivery and expression of the therapeutic gene to the desired target. A vector must be used, one that transports a gene or genes to the target. The vector should be innocuous, sustainable, and, of course, able to deliver a genetic sequence that can be inserted …


The training manual on gender responsive budgeting (GRB) is intended to build the capacity of UNFPA and UNIFEM staff in applying gender budget analysis tools in their programming around gender equality and womens rights it will also assist them in supporting gender budget initiatives wherever they exist. The manual specifically seeks to build understanding of GRB as a tool for promoting gender equity accountability to womens rights as well as efficiency and transparency in budget policies and processes. It is anticipated that this manual will develop skills required to effectively engage in mainstreaming gender in planning and budgeting processes at country level. It is also foreseen that UNFPA and UNIFEM will be using the manual to build teams of experts that can support the growing demand from national partners for capacity building in GRB. The training manual adds value to the wealth of training resources on GRB firstly through a focus on the applicability of gender responsive budgeting to reproductive health and secondly through a presentation of sector-specific examples and case studies dealing with maternal health gender and HIV/AIDS and violence against women. The manual draws on the rich experience and lessons learnt from UNIFEMs programming on gender budgeting in more than thirty countries since early 2000. It further encapsulates the understanding that gender responsive budgeting is an essential element in any serious political commitment towards gender equality and lays out approaches to align budgets with requirements for the achievement of womens rights. (excerpt)


U.v. photolysis of diacyl disulphides gives acylthiyl radicals [RC(O)S·] which react with alkenes, trialkyl phosphites, and dialkyl sulphides to give adducts which have been detected by e.s.r. spectroscopy.


Objective:To study the MR imaging of complex perianal fistulas and its diagnosis valuation.Methods:48 patients suspected of complex perianal fistulas were accepted MR scanning of pelvic without contrast,scanning sequences,including FSE-T1WI,T2WI,T2WI-fatsat and STIR in the transverse plane,STIR and T2WI in the sagittal plane,STIR and T2WI-fatsat in the coronal plane.The imaging of the complex perianal fistulas was analyzed.The relations among the fistula and internal and external anal sphincter,the types and the display of the internal and external openings were assessed,and the diagnosis with the operation results was compared.Results:Fistula showed low signal in T1WI and high signal in T2WI, T2WI-fatsat and STIR;it was more distinct on fatsat sequences.Compared with the operation results,the correct rate of MRI diagnosis was 96.9%(fistulas or abscesses),82.4%(internal openings),100%(external openings),86.7%(types),respectively.Conclusion:MRI is an important diagnostic method for complex perianal fistula,and has great value.


Objective: To observe the curative effect of gemcitabine combined with S-1 on patients with advanced breast cancer.Methods: A total of 31 patients with advanced breast cancer were enrolled into this study.All the subjects were treated with gemcitabine(1 000 mg.m-2,iv 0.5 h) and S-1(80 mg.m-2.d-1,oral administration after meal,two times,d1-d14).Three weeks was a cycle.Minimum 2 cycles were given.The following parameters of all the subjects were observed: clinical curative effect and adverse reactions.Results: The curative effect and adverse reactions could be evaluated in 31 patients with 2 of CR,8 of PR,13 of SD,8 of PD,the response rate and clinical benefit rate were 32.26% and 74.19%,respectively.The most common adverse reactions were hematological and digestive toxic reaction.Conclusion: Patients with anthracycline-and(or) taxanes-resistant advanced breast cancer who were treated with gemcitabine combined with S-1 have a better curative effect.And their adverse reactions were also small.So it is worthy of uses in clinical decisions.


CORONARY embolism is an uncommon condition that usually complicates some acquired disease such as valvular endocarditis or processes associated with thrombi or tumors within the left side of the heart.1 Rarely, coronary embolism may be paradoxical —that is, it may result from the escape of foreign material from the right side of the heart. The most common form of paradoxical embolism, whether it involves the coronary or other systemic arteries, is a complication of recurrent pulmonary embolism in subjects with developmentally normal hearts in which a valvular competent patent foramen ovale is present.2 In this circumstance nonfatal pulmonary embolism may . . .


This report describes an instrument recently developed for profiling self concepts and provides some background through a discussion of the rationale and development of the procedure. The Self Concept Profiling Technique (SCPT) has both a projective and a paired comparisons phase through ':hick ate examined five occupational and occupationally-relevant self concepts: .(1) self-as-a-person-at-work; (2) the ideal person for my job; (3) my ideal job; (4) ideal self; and (5) self-as-a-person-in-general. It is felt that this procedure permits vocation, with reference to specific occupations, to be eapirically investigated. Initial results allow the conclusion that the SCPT has potential value in counseling and gui6ance, both in a diagnostic and an educative role, and say also be useful in educational and clinical contexts as well as in research. (TL) .00.0.0.0.1.000000001.0n. R.0.0yr c ^"e. 9/1. envacor.,...a...racy INFORMATION SYSTEM FOR VOCATIONAL DECISIONS Project Report No 32 THE SELF CONCEPTS PROFILING TECHNIQUE! A PROCEDURi FOR THE EXPLORATION OF SELF CONCEPT SYSTEMS Terence J. OfMaDoney Thu paper sae supported in part by Grant No. OSG-1-6-061619-2240 of the United States Office of Education under torso of the Vonations1 Education Act of 1963. Orainate Schad of adveetion NerVard University Ua IMENT Of Hi Atm. tOUCATiONa WELFARE OFFICE Of EDUCATION TroS DOCUMENT MAE BEEN A EPA° DU:ED MAME As III CEVIO FROM TIF EFISOW OR ONGANIATION 00,G ;NAT IF G IT POINTS OF vIEW OR OFN IONS S1AFED 00 NOT locissmiLy AEIRIStAt OfF,C,A1 OFFICE DE EDU CAFON POVII$OS DA POtiCv


Scaling of MOS technology introduces issues to the memory design like read and write latency, leakage current, reduction in Static Voltage Noise Margin (SVNM), and stability. The parasitic capacitance existing on the bitline can have a significant impact on the memory performance and capacity. This paper discusses the need and working of an improved auxiliary circuit assisted sense amplifier design. The improved sense amplifier design was further used in a case study of 1-Kb memory using conventional 6T SRAM cell. The architecture is designed and implemented in 65-nm CMOS technology with a supply voltage of 0.9 V. The results show that the design achieves the operating frequency of 2.5 GHz with a power consumption of 13.5 mW. Also. the timing margin was improved by 22.3% compared to the strong-arm latch sense amplifier.


Genotoxicity of tamoxifen and structural analogues of tamoxifen Adrian Davies Tamoxifen is a potent hepatocarcinogen in rats and causes a low incidence of endometrial cancer in women. This thesis investigates the activation of tamoxifen and structural analogues o f tamoxifen by cytochrome P450s and peroxidase. In human lymphoblastoma derived cell lines expressing cDNAs for different human CYPisoforms, tamoxifen, toremifene and 4-hydroxytamoxifen were clastogenic. Micronucleus formation was dependent on the dose of drug used and was not seen in cell lines not expressing these CYP isoenzymes. Results showed that CYP3A4 was the most important mono-oxygenase in the activation of these drugs. Clastogenicity was not detected when synthetic a-hydroxytamoxifen or clomiphene were used. It was shown that in vitro, a horseradish peroxidase/H20 2 system could catalyse the Ndemethylation and ^-oxidation of tamoxifen and toremifene. Activation of [14C]tamoxifen or toremifene by this system was demonstrated by their irreversible binding to protein or to DNA. This reaction was catalysed by a number of peroxidases, including prostaglandin synthase. In the presence of DNA, activation of tamoxifen, 4-hydroxytamoxifen or toremifene resulted in the formation of 32P-postlabelled DNA adducts. 4Hydroxytamoxifen was broken down by peroxidases much faster than tamoxifen. Reaction products, detected by HPLC-electrospray mass spectrometry, had structures consistent with 4-hydroxytamoxifen dimers. Incubation of 4-hydroxytamoxifen with horseradish peroxidase, H20 2, glutathione and the radical trap DMPO leads to the formation of a glutathione thiyl radical that can be detected with electron paramagnetic resonance spectrometry. The presence of the thiyl radical supports the proposal for the formation of a phenoxyl radical from 4-hydroxytamoxifen. Incubation of model resorufin substrates with human uterine microsomal fractions permitted the detection of low levels of NADPH dependent metabolism. However, with tamoxifen as substrate, CYP or peroxidase dependent activation, if it occurred, was below the limit o f detection. The results of the work described in this thesis show that peroxidase activation o f tamoxifen in uterine tissues of rats or women probably does not play a significant role. 1


In this paper,an Organic Rankine cycle system using medium and low-grade solar energy is established,and the net power output reaches 100 kW.An organic radial turbine is designed for the system.According to the CFD simulation results,there is little difference between the calculated value and the design value,thus the design of turbine in this paper meets the requirements.The flow state of the organic working fluid in the turbine is fine and no separating vortex exists in the turbine.The system designed in this paper can be applied in utilization of medium and low-grade solar energy,and it can provide guidance for practical uses in the near future.


Given two integers, say and , the quotient may or may not be an integer (e.g., ½½ but ½¾ ¾). Number theory concerns the former case, and discovers criteria upon which one can decide about divisibility of two integers. More formally, for ¼ we say that divides if there is another integer such that and we write. In short: if and only if ¾ This simple definition leads to many properties of divisibility. For example, let us establish the following lemma. Proof. We give a direct proof. From the definition of divisibility and the hypotheses we know that there are integers Ø and × such that ØØØ ××× Hence · ´× · ص Since × · Ø is an integer, we prove that´· µ. We already noted that an integer may be or not divisible by another integer. However, when dividing one number by another there is always a quotient and a remainder. More precisely, if and are positive integers then there is a unique Õ and Ö such that Õ · Ö where ¼ Ö Ö is a remainder. Observe that the remainder can take only values ¼ ½ ½.


Abstract In the literature, hyperjerk systems raised up meaningful interest due to their simple and elegant structure as well as their complex dynamical features. In this work, we propose a novel 4D autonomous hyperjerk system which the particularity resides on the type of its nonlinearity namely the Van der Pol nonlinearity. The dynamics of this hyperjerk system is assessed thanks to the well-known nonlinear dynamic tools such as time series, bifurcation diagrams, Lyapunov exponent spectrum, two-parameter phase diagram, and phase portraits. As important result, it is established that the system presents a particular phenomenon of hysteretic dynamics that leads to the coexistence of attractors. Next, through the calculation of the Hamiltonian energy, we show that this latter depends on all the variables of the novel hyperjerk system. Furthermore, basing on an adaptive backstepping method whose target is a function of the states of the error system, a new controller is designed to carry out from t = 30, complete chaotic synchronization of the identical novel hyperjerk chaotic systems. Likewise, PSpice (9.2 full version) based simulations are presented in detail to confirm the feasibility of the theoretical model. One of the key points of this work is the designing in PSpice environment of this new adaptive backstepping controller to validate both theoretical and numerical synchronization results. Finally, our experimental measurements in the laboratory are in good agreement with the numerical and analog results.


Twenty four lactating Zaraibi goats in mid lactation were used in a 2 x 2 factorial experimental design to evaluate two different sources of ruminally degradable non structural carbohydrates (high and low RDNSC) and two different sources of ruminally degradable protein (high and low RDP). Four experimental diets were formulated to study their effects on digestion coefficients, some blood constituents and milk production and its composition. The obtained results indicated that digestibility coefficients for DM, OM, CP and NFE and the nutritive value in terms of TDN and DCP% were significantly (P<0.05) higher for goats received low RDP and high RDNSC diets than those received high RDP and low RDNSC diets. The concentration of plasma urea-N was decreased (P<0.05) when goats were fed low RDP diets than those fed high RDP ones, whereas the concentrations of total protein, albumin and globulin were increased indicating once more better utilization of low RDP. Regardless the RDP, plasma urea-N was significantly (P<0.05) lower in goats fed high RDNSC diets than in those fed low RDNSC diets. Yields of milk, 4% fat-corrected milk (4%-FCM) and milk components were higher (P<0.05) when goats fed low RDP diets than those fed high RDP ones. Milk non-protein-nitrogen (NPN) was lower (P<0.05) with low RDP diets. On the other hand, yield of true protein nitrogen, casein nitrogen, whey nitrogen and unsaturated fatty acids in milk were higher (P<0.05) with goats fed low RDP than those fed high RDP. Regardless the RDP content of the tested diets, a slight improvement in milk yield and 4%-FCM detected for goats given high RDNSC diets compared to those given low RDNSC ones without significant differences. Goats received low RDP with high RDNSC (diet 4) were higher and more persistent for milk yield during the experimental period. On the other hand goats received diets contained high RDP with high RDNSC produced the lowest milk yield.


Whether college students have good relationships with each other is a comprehension reflection of their mental health and their ability to adapt themselves to society.Harmonoius human relationships not noly can improoe college students lenrning efficiency,but also can make them more mature.Sports activities can provide a wide platform for college students to communicate with each other.And so colleges should use this platform to promoto the shaping and development of college students harmonious relationships.


Summary. The constituent parts of a five component behavioural intervention package are described and the effect of the intervention on the on-task behaviour of two "disruptive" secondary school classes reported. It is claimed that levels of pupil on-task behaviour were significantly increased in both classes. Concomitant changes in teacher behaviour were also reported and it is suggested that increased levels of pupil on-task behaviour may have elicited higher levels of positive verbal behaviour from the teachers.


There can be few readers of this journal who are not familiar with John Iliffe's Africans: The History of a Continent. Appearing in 1995, it rapidly established itself as the most authoritative single-volume history of Africa, offering a bold and compelling synthesis of the continent's past. I would guess – although I have no way of knowing this beyond casual exchanges with academic colleagues, as well as the evidence of my own well-thumbed copy – that it is the most widely used textbook for African history in the English-speaking world. Now, 14 years after its first publication, we have a revised edition, produced by Cambridge University Press in a new, and I think more attractive, format. In light of the first edition's great success, it was unlikely that Iliffe would offer a radically different text this time around, and he has not done so. As indicated in a new preface, only 2 of the 12 original chapters, those on prehistory and on the Atlantic slave trade, have been extensively revised (although these retain their established structure and overall argument). The main change is the addition of a new final chapter entitled 'In the time of AIDS' that extends the narrative beyond the closing point of the first edition, the South African elections of 1994, to events of 2006. Yet even Iliffe's minor alterations and bibliographical updates make for fascinating reading. Given the importance of this book as a state-of-the-art survey of historical scholarship on Africa, these changes point to how the field has been evolving over the past decade. Its appearance provides an opportunity to reflect upon these developments. Africans, as is well known, takes as it overriding theme the population history of the continent. Some reviewers of the first edition took issue with the use of such a framework for understanding the entirety of the African past. In a review article for this journal, Thomas Spear, while otherwise praising the work's dazzling scholarship, concluded that, however much Iliffe 'sees Africa's population history as a function of Africa's sparse soils, erratic rainfall and the social strategies Africans adopted to exploit these, his argument often veers towards neo-Malthusian determinism in which population itself becomes the critical independent variable'. I do not wish to rehearse these debates here, beyond making the point that while to some extent I share Spear's concern over the sometimes implicit environmental and demographic determinism, I do not feel that this detracts in any serious way from the utility of the work as a textbook. Textbooks need big ideas, or even one big idea, if they are not to become soulless


The outbreak of SARS in 2002-2003 caused by SARS-CoV, and the pandemic of COVID-19 in 2020 caused by 2019-nCoV (SARS-CoV-2), have threatened human health globally and raised the urgency to develop effective antivirals against the viruses. In this study, we expressed and purified the RNA-dependent RNA polymerase (RdRp) nsp12 of SARS-CoV and developed a primer extension assay for the evaluation of nsp12 activity. We found that nsp12 could efficiently extend single-stranded RNA, while having low activity towards double-stranded RNA. Nsp12 required a catalytic metal (Mg2+ or Mn2+) for polymerase activity and the activity was also K+-dependent, while Na+ promoted pyrophosphorylation, the reverse process of polymerization. To identify antivirals against nsp12, a competitive assay was developed containing 4 natural rNTPs and a nucleotide analog, and the inhibitory effects of 24 FDA-approved nucleotide analogs were evaluated in their corresponding active triphosphate forms. Ten of the analogs, including 2 HIV NRTIs, could inhibit the RNA extension of nsp12 by more than 40%. The 10 hits were verified which showed dose-dependent inhibition. In addition, the 24 nucleotide analogs were screened on SARS-CoV primase nsp8 which revealed stavudine and remdesivir were specific inhibitors to nsp12. Furthermore, the 2 HIV NRTIs were evaluated on 2019-nCoV nsp12 which showed inhibition as well. Then we expanded the evaluation to all 8 FDA-approved HIV NRTIs and discovered 5 of them, tenofovir, stavudine, abacavir, zidovudine and zalcitabine, could inhibit the RNA extension by nsp12 of SARS-CoV and 2019-nCoV. In conclusion, 5 FDA-approved HIV NRTIs inhibited the RNA extension by nsp12 and were promising candidates for the treatment of SARS and COVID-19.


A tapered (lossy) dielectric slab backed by a sinusoidal conducting plane is studied as a paradigm of bouncing-ray chaos for 2D plane-wave scattering. A simple 2D ray analysis reveals a rich variety of possible ray paths, featuring chaos for almost all directions of incidence. Several interesting properties emerge, which suggest a number of possible applications.


This paper is dedicated to a comparison of transitive/intransitive verb alternation in Japanese and Chinese. Discussions are focused upon three grammatical elements: monosyllabic verbs, compound verbs and constructions. The findings reveal that the two languages share similarities in two aspects: (i). transitive and intransitive verbs share the same word form; (ii) transitive and intransitive verbs can derive from the same adjective stems. Significant distinctions are also seen between the two: anticausativisation and decausativisation in Japanese are mainly facilitated in morphological level, e.g. anticausativisation is realised through the morpheme '-e-' and decausativisation is conveyed by '-ar-'. The morpheme '-e-' can be used with both intransitive and transitive verbs. Regarding Chinese, lexical and syntax have a curial role to play in transitive/intransitive verb alternation. Decausativisation appears the most favourable strategy of the alternation. Two ways of decausativisation is observed: schema of [action + resultative state]; verb compounds (V-V). Three types of V-Vs are possible for this strategy, i.e. Predicate-Complement V-V, Modifier-Head V-V and Coordinative V-V. Among them, predicate-complement V-V has the largest token of decausativisation. Moreover, constraints on Chinese anticausativisation and decausativisation are seen. When a resultative complment predicate an internal argument, the higher the agentivity that implies manner of action, the greater the unlikelihood of anticausativisation. In decausativisation, the internal argument that accepts the change of state is limited to the 'possessive relationship'.


The bearing ring has the characteristics of weak texture and high reflection, which easily cause errors in stereo vision matching. To address these issues, this paper proposes a two-stage spatial pose detection method for bearing rings based on YOLOv5 and binocular vision. In Stage 1 called Pre-positioning: the YOLOv5 is used to detect the unobstructed bearing ring; then binocular vision is employed to locate the unobstructed bearing ring; and a line laser projection is performed on the unobstructed bearing ring for fine positioning. In Stage 2 called Fine-positioning: the YOLOv5 is used again to locate the line laser stripes projected on the upper surface of the bearing ring, and then the detected line laser stripes are used to calculate the robot's best grasping pose. The practical application showed that the introduction of line laser solved the problem of weak texture matching, and the application of yolov5 solved the problems of high reflection on the bearing ring surfaces and strong noises after laser reflection. Experiments showed that YOLOv5 detected the unobstructed bearing rings and laser line stripes with 98.5% and 99.3% mAP, respectively, and this method had a 96.3% grasping success rate.


The excessive repetition of the same sounds makes The Alliterative Morie Arthure (AM4) unique among the alliterative poems of the fourteenth century. Sound repetition, particularly the repetition of /r/ in the AM4, is illuminating because it reveals the special treatment of the phrase the round table within the verse line. The present paper examines /r/ in the alliteration of the AM4 and analyzes the lines that contain the round table in order to prove that the poet requires this phrase to receive full metrical significance. The fixed location of the round table in the second half-line of the AM4 is due to the metrical constraints which impose overwhelming alliteration of the /r/ sound. Through various observations of Ir/, the paper reveals that the AM4 poet uses excessive repetition of the same sound more than required by alliterative meter, expanding the repetition of the same sound beyond the verse line. Yet he is extremely inflexible regarding the alliteration of a line that contains the round table even though he could have chosen a different word order or different alliteration sounds as seen in other ME works on King Arthur. Intricate sound repetition plays an important role in creating unity not only within the line but also in a group of consecutive lines in the AM4. Through the examination of Ir/ in alliteration and the analysis of the lines that contain the round table it becomes clear that the poet always requires the particular phrase, the round table, to receive full metrical stress. This paper compares the round table in the AM4 with the round table in other ME alliterative works about King Arthur such as Sir Gawain and the Green Knight (SGGK), The Stanzaic Morie Arthur (SM4), Merlin, and Sir Thomas Malory's Le Morie Darthur. While the other works allow the adjective round and the noun table to appear in the reversed order, the AM4 never does so. The other texts are flexible in the selection of the noun that precedes the round table while the AM4 always chooses the noun that alliterates on Ir/. After considering if this inflexibility can be interpreted as a formulaic


By focusing on the recent events in the Middle East, that have pushed many to flee and seek refuge in neighboring countries or in Europe, we investigate dynamics of label use in social media, the emergent patterns of labeling that can cause further disaffection and tension, and the sentiments associated with the different labels. To achieve this, we examine key labels pertaining to the refugee/migrant crisis and their usage in the user comment thread of a highly viewed and informational video of the crisis on YouTube. The use of labels indicate that migration issues are being framed not only through labels characterizing the crisis but also by their describing the individuals themselves. The sentiments associated with these labels depart from what one would normally expect; in particular, negative sentiment is attached to labels that would otherwise be deemed neutral or positive. Interestingly, both positive and negative labels exhibit increased negativity across time. Using topic modeling and sentiment analysis jointly, we discover that the latent topics of the most positive comments show more overlap than those topics of the most negative comments, which are more focused and partitioned. In terms of sentiment, we find that labels indicating some degree of perceived agency or opportunity, such as 'migrant' or 'immigrant', are embedded in less sympathetic comments than those labels indicating a need to escape war-torn regions or persecution (e.g., asylum seeker or refugee). Our study offers valuable insights into the direction of public sentiment and the nature of discussions surrounding this significant societal event, as well as the nature of online opinion sharing.


Staphylococcus lugdunensis is a coagulase negative Staphylococcus (CoNS) species with the potential to cause aggressive infection. Guidance surrounding S. lugdunensis bacteremia (SLB) is lacking, especially in the case of a single positive set of blood cultures.

 We performed a multicenter, retrospective observational cohort review of adult patients with SLB from at least one blood culture set within the University of Maryland Medical System from November 2015-November 2019. Objectives were to (1) describe baseline characteristics, (2) compare available criteria for evaluating clinical significance, and (3) evaluate the clinical outcomes among patients with SLB in 1 vs ≥2 positive blood culture sets. Descriptive statistics with Chi-squared and Mann-Whitney U tests were carried out.

 There were 5,548 CoNS-positive blood culture sets, 49 (0.88%) with S. lugdunensis comprising 36 adult patients (24 with 1 positive set and 12 with ≥2 positive sets). Patients with ≥2 positive sets were more likely to be on hemodialysis (HD) (p=0.029) and to have an HD catheter present (p=0.10) (Table 1). Thirty-five of the 36 patients fulfilled at least one of the following: systemic inflammatory response syndrome (SIRS), Souvenir criteria, or clinical criteria (infectious focus on imaging and/or second positive culture site) (Table 2). Twenty-eight (78%) patients were treated with antimicrobial therapy and/or central line removal. SIRS criteria were met more often among patients with 1 positive set (p=0.05). Patients with ≥2 positive sets were more often treated with antibiotics for longer than 2 weeks (p=0.02). The mean time of positive cultures to discharge was 11 days and was longer for patients with only one set of positive blood cultures (13 vs. 6 days), although this difference was not statistically significant (p=0.29) (Table 3).

 SLB was rare and occurred more frequently as a single set of positive blood cultures. Though limited by sample size, this study found similar patient characteristics, clinical significance and outcomes between patients with one set and those with ≥2 sets of blood cultures positive for S. lugdunensis. Given the potential severity of SLB, it seems prudent to treat S. lugdunensis in a single blood culture, but larger studies are needed.

 All Authors: No reported disclosures


Th e index of prevalence of tuberculosis is stipulated by the number of patients with active tuberculosis, who are registered at untituberculous establishments. On the background of stabilization of the index of prevalence of tuberculosis the indices of prevalence of tuberculosis with bacterial discharge, with destruction of lung tissue, with multiple drug-resistance and fi bro-cavernous tuberculosis, mainly at the expense of decrease of the eff ectiveness of treatment and dispensary observation of patients have been increased.


Background: Congenital diaphragmatic hernia (CDH) is a common congenital anomaly with significant morbidity and mortality. Few surveys have been reported regarding the prenatal status, clinical course and postnatal outcome of CDH. The symptoms and prognosis depend on the location of the defect and associated anomalies. Objectives: The aim of this study was to examine the effect of clinical factors on the prognosis of CDH in our pediatric hospital. Methods: We analyzed 74 records of CDH neonates referred to our center for surgery between 2008 and 2015. We investigated the associated factors with the outcomes of CDH using the information extracted from the hospital records. The perinatal status, clinical course and the postnatal outcome were reviewed. Survival was defined as infants alive at hospital discharge. Results: A total of 74 CDH cases were identified. Of these, 27 (36.5%) cases were females and 47 (63.5%) males. The type of hernia in 73 (98.6%) cases was Bochdaleck and 1 (1.4%) case was Morgagni. Seventeen (23.9%) cases had right-sided CDH and 57 (76.1%) cases left- sided CDH. Also, 90.5% underwent open surgery and 9.5% thoracoscopic repair. Forty-seven (63.5%) cases survived and 27 (36.5%) cases succumbed. The survival rate had a significant statistical correlation with the place of delivery. The death rate was higher in neonates referred from other hospitals in our town in comparison to other cities (P = 0.008). Also, the resuscitation history, the status at admission (intubated or not intubated) (P = 0.00), existence of skeletal anomalies (P = 0.02) and brain hemorrhage (P = 0.045) had a significant correlation with the survival rate. The side of herniation, herniated organs, type of operation (open or thoracoscopic), cardiac and renal anomalies and age at the time of surgery had no significant correlation with outcome. Conclusions: The overall mortality rate in CDH was high in our series. Neonates with CDH should be delivered in institutes with the neonatal intensive care unit and surgery ward to prevent complications. To achieve better survival rates, pulmonary hypertension should intensively be controlled and the extracorporeal membrane oxygenation should be used in selected cases.


Nickel grids are used in various methods (e.g., in immunocytochemistry) where chemically inert grids are required. Recently (Neiss 1983) we have used formvar-coated nickel grids when removing osmium from mounted ultrathin sections with 10% periodic acid (Lewis and Knight 1977). This is possible because nickel, unlike copper, adequately withstands the oxidation necessary for osmium removal. Handling sections on nickel grids avoids the disadvantages of free-floating sections, whose use for osmium removal has been recommended by Lewis and Knight (1977, chapter 2.2.3).


Hypertensive disorders complicate about 10 % of all pregnancies worldwide. Hypertension, along with haemorrhage and infection form a deadly triad accounting for a major share of maternal morbidity and mortality. The World Health Organisation systematically reviews maternal mortality worldwide and in developed countries 16% of maternal deaths were reported to be due to hypertensive disorders. In India hypertensive disorders account for the third most important cause of maternal mortality.


Historically, one of the most famous and endless controversies in science and science education is on the origin of life. Since 1859, when the 1st edition of 'On The Origin Of Species' written by Charles Darwin had been published in London. evolutionism had the support of the public and scholars Creationists. however, argue recently that the scientific creationism is supported by the vast geological, biological, palaeontological biochemical and even astronomical evidences. Strong arguments of creationists stirred up the sharpening critiques of evolutionists. In this paper. the author summarizes three recent evolutionary critiques on creationism and refutes them from creationist view. After examing the critiques. we find that they are not based on the decisive evolutionary evidences but considerable conjectures And we show that the majority of critiques stem from the lack of communication in the academic communities.


The behavior of dispersed particles in a turbulent round jet is experimentally investigated. The role of particle-to-fluid density ratio [Formula: see text] is analyzed by inspecting particle velocity fields and preferential concentration at four different ratios, from 0.7 to 19.3. The jet near-field region, i.e., up to [Formula: see text], is analyzed and compared to the unladen case. Particle-to-fluid density ratio is reported to have a strong impact on particle velocity field structure, in terms of jet transition and self-similar region as well as on turbulent fluctuations. Concentrations of particles show that increasing particle density corresponds to larger departure from uniformity. This occurrence is limited to the region [Formula: see text], where also the largest differences of average and fluctuating velocities with respect to the unladen case are measured.


We investigate a two players zero sum differential game with incomplete information on the initial state: The first player has a private information on the initial state while the second player knows only a probability distribution on the initial state. This could be view as a generalization to differential games of the famous Aumann-Maschler framework for repeated games. In an article of the first author, the existence of the value in random strategies was obtained for a finite number of initial conditions (the probability distribution is a finite combination of Dirac measures). The main novelty of the present work consists in : first extending the result on the existence of a value in random strategies for infinite number of initial conditions and second - and mainly - proving the existence of a value in pure strategies when the initial probability distribution is regular enough (without atoms).


The title compound, C18H15NO3, is a potent new herbicide containing the pyrrolidine-2,4-dione ring system. In the crystalline state, the molecular skeleton contains one enol hydrogen-bonded moiety, formed from benzoyl Czdbnd;O isomerization.


To understand the effect of rapidly changing winter climate on arctic tundra ecosystems, small rodents constitute a key indicator. Their population density cycles are very sensitive to changing winter climate and affect the entire food web. Monitoring arctic rodent populations through the long winter has until now been impeded by the snow cover. However, belowsnow camera traps provide a potential solution to this impediment. Here, I conduct the first extensive assessment of the utility of such camera traps to analyse the dynamics of a rodent community during the Arctic winter. The study was conducted over winter 2014-2015 (9 1⁄2 months) with 44 camera traps in a landscape-scale design on Varanger Peninsula, northern Norway. I investigated whether the functionality of the camera traps was compromised by the harsh environmental conditions in the tundra and assessed the applicability of the recorded data for modelling occupancy dynamics of the focal rodent community. For modelling purpose, environmental variables were gathered both from the camera trap images and from in situ habitat measurements at the trap sites. Of the 44 camera traps, 19 had technical failures, mostly caused by spring melt flooding, while 14 were temporarily filled with drifting snow during the winter. In total, the cameras were motion-triggered 16445 times by three small rodent species (Norwegian lemming (Lemmus lemmus), grey-sided vole (Myodes rufocanus) and tundra voles (Microtus oeconomus)). The modelled weekly occupancy declined steeply for all three species at the onset of the winter but had a tendency for recovery for two of the species in spring. Occupancy probability was shown to be higher in habitats with rich ground-structure and vegetation and snow-free periods. However, the effect of environmental variables differed between species and remains uncertain due to data limitation. The detection probability for the three species was estimated to range between 0.49 and 0.62 per week. I conclude that, with some adaptations in the setup, the subnivean camera traps are well suited for long-term application in order to obtain robust inferences on the yearround occupancy dynamics of low arctic small rodent communities.


The high-level contribution of this paper is a simulation based analysis of the network connectivity, hop count and lifetime of the routes determined for mobile ad hoc networks (MANETs) using the Gauss-Markov mobility model. The Random Waypoint mobility model is used as a benchmark in the simulation studies. Two kinds of routes are determined: routes with the longest lifetime (stable paths) and routes with the minimum hop count. Extensive simulations have been conducted for different network density, node mobility values and different values of the degree of randomness parameter for the Gauss-Markov model. In low-density network scenarios, we observe that the network connectivity under the Gauss-Markov model is significantly lower than that obtained under the Random Waypoint model. In moderate and high density network scenarios, the network connectivity obtained under the two mobility models is almost equal. The minimum hop paths determined under the Gauss-Markov model have a larger number of hops than those computed under the Random Waypoint model. The lifetime of stable paths determined under the Gauss-Markov model is smaller than those determined under the Random Waypoint model. Low-density networks using the Gauss-Markov mobility model attain larger connectivity for intermediate values of the degree of randomness parameter, while the connectivity of moderate and high-density networks is not significantly dependent on the degree of randomness parameter. The minimum hop count of the paths is not much affected by different values of the degree of randomness parameter, while maximum lifetime stable paths are obtained for larger intermediate values of the degree of randomness parameter, but not for unity.


The purpose of this study was to examine the influence of professional commitment, locus of control, seriousness of wrongdoing and ethnic group on whistleblowing intentions. The respondents in this research is financial staff in working units of  local government (SKPD) DKI Jakarta. The sample in this research were 39 financial staff in 7 working unit of local government (SKPD) DKI Jakarta. The method of determining the sample uses convenience sampling method. Methods of analysis to test the hypothesis is multiple regression analysis. The results showed that the seriousness of wrongdoing affect the whistleblowing intentions. However, professional commitment, locus of control and ethnic group have no effect on whistleblowing intentions.


A 4-year-old boy had three neuroepithelial cysts, one in the third ventricle and two in the supratentorial subarachnoid space, and also had stenosis of the cerebral aqueduct, obstructive internal hydrocephalus, frontoethmoidal meningoencephalocele, and right microphthalmia. The occurrence of these combined lesions supports the congenitally derived nature of the cysts. The cysts originated from neuroepithelium including ectopic ependyma-lined structures. The exception may be those cysts arising in or near the floor of the third ventricle; these cysts could be derived from the cleft of Rathke's pouch, an endodermal derivative. Folding of the neuroepithelium in contact with mesenchymaor neuroglial tissue is proposed as the mode of formation of most "colloid" cysts. Review of the literature as well as our experience indicates that neuroepithelial cysts are widely distributed throughout the central nervous system.


Tourists and Wild-life photographers are often hindered in capturing their cherished images or videos by a fence that limits accessibility to the scene of interest. The situation has been exacerbated by growing concerns of security at public places and a need exists to provide a tool that can be used for post-processing such fenced videos to produce a de-fenced image. There are several challenges in this problem, we identify them as Robust detection of fence/occlusions and Estimating pixel motion of background scenes and Filling in the fence/occlusions by utilizing information in multiple frames of the input video. In this work, we aim to build an automatic post-processing tool that can efficiently rid the input video of occlusion artifacts like fences. Our work is distinguished by two major contributions. The first is the introduction of learning based technique to detect the fences patterns with complicated backgrounds. The second is the formulation of objective function and further minimization through loopy belief propagation to fill-in the fence pixels. We observe that grids of Histogram of oriented gradients descriptor using Support vector machines based classifier significantly outperforms detection accuracy of texels in a lattice. We present results of experiments using several real-world videos to demonstrate the effectiveness of the proposed fence detection and de-fencing algorithm.


The essays in this collection, written in honor of noted philosopher Annette Baier, reflect the influence of her work in the area of philosophical naturalism. Naturalism has ethical and epistemological implications that often run contrary to the rationalist tendencies of academic philosophy. These essays collectively examine the four main themes of Baier's naturalism: a general resistance to thinking of persons atomistically, the importance of trust between persons and the mutual dependence of persons, the positive role of emotions in human judgment, and the modes of self-correction available to persons so conceived. Many of the contributors to this volume take a historical approach, dealing particularly with Descartes and Hume. Others develop Baier's naturalistic themes for feminist philosophical purposes. All of these essays offer original, and sometimes polemical, insights into the history of philosophy. This collection will be welcomed by philosophers, ethicists, feminists, and political theorists.


This report discusses two tasks: (1) introduction of the Mark 15-MARCO library within the context of an overview of the methodology of MARCO and (2) assessment of the accuracy of MARCO calculations of the Mark 15 MOC at beginning of cycle.


The article presents a review of the book "Turkish Migration to the United States: From Ottoman Times to the Present," edited by A. Deniz Balgamis and Kemal H. Karpat.