The attractive branch of the interaction potentials with the surface of gold have been computed for a large variety of atomic systems: the hydrogen atom, noble gases (He, Ne, Ar, Kr, Xe), alkali atoms (Li, Na, K, Rb, Cs) and alkaline atoms (Be, Mg, Ca, Sr, Ba). The results include highly accurate dynamic polarizabilities for the helium atom calculated using a variational method and explicitly correlated wavefunctions. For other atoms considered we used the data available in the literature. The interaction potentials include both the effects of retardation of the electromagnetic interactions and a realistic representation of the optical response function of gold (beyond the approximation of a perfect conductor). An explicit comparison of our result to the interaction between an atom and a perfect conductor is given.


The work exposes the result of a bibliographic search related to the pedagogical actions effected in basic education, in a close dialogue between the field of Art and Informatics for the creation of digital art in basic education. The text is linked to an ongoing research has as its general objective analyze how the process of reframing images can contribute to the expansion of the reconstructive attitude based on the technique of digital collage. Therefore, the study presents a thematic delimitation from experience reports focused on the production and editing of static digital images considering the role Brazilian Journal of Development Braz. J. of Develop., Curitiba, v. 6, n. 9 , p.73270-73280, sep. 2020. ISSN 2525-8761 73271 of the teacher and the computer as mediators of this process. In this perspective, the source of research was through the search for articles published in the annals of two national events aimed at teaching Art: Annual Congress of the Federation of Art Educators in Brazil (Confaeb) and the Meeting of the National Association of Researchers in Plastic Arts (Anpap Meeting). In this search, three experience reports from basic education teachers were selected and analyzed, each with its teaching methodology, however, favorable to the same perspective with regard to the knowledge integration process in the areas of Art and Informatics as a breeding ground for the teacher for the possibilities of work that problematize the relations on the use, production and distribution of digital images.


This paper sets out a proposal for a state-provided Job Guarantee (JG) for people with psychiatric disability. The role of the state in this employment model is twofold. First, the state must provide the quantum of JG johs required. Second, the state must ensure that the design of jobs is flexible enough to meet the heterogeneous and variable support needs of workers. This will require effective integration of the JG scheme with mental health, rehabilitation and einployment support services. The paper evaluates the effectiveness of disability employment reforms in assisting people to find, or return to, paid work. We argue that the poor employment outcomes from current programs establish the need for a paradigm shift in employment policy for people with psychiatric disability.


In this work a new mechanical device to improve the gas flow in cyclones by pressure drop reduction is presented and discussed. This behavior occurs due to the effects of introducing swirling breakdown phenomenon at the inlet of the vortex finder tube. The device consists of a tube with two gas inlets in an appositive spiral flux that produces a sudden reduction in the tangential velocity peak responsible for practically 80 % of the pressure drop in cyclones. In turn, peak reduction causes a decrease in pressure drop by a breakdown of the swirling, and because of this the solid particles tend to move faster toward the wall , increasing collection efficiency. As a result of this phenomenon the overall performance of cyclones is improved. Numerical simulations with 3-D, transient, asymmetric and anisotropic turbulence closure by differential Reynolds stress for Lapple and Stairmand standard geometries of 0.3 m in diameter, show a reduction in pressure drop of 20 % and a shift of the tangential velocity peak toward the wall. All numerical experiments were carried out with a commercial CFD code showing numerical stability and good convergence rates with high-order interpolation schemes, SIMPLEC pressure-velocity coupling and other numerical features.


Photon counting lidar has an ultra-high sensitivity which can be hundreds even thousands of times higher than the linear detection lidar. It can significantly increase the system's capability of detection rang and imaging density, saving size and power consumings in airborne or space-borne applications. Based on Geiger-mode Si avalanche photodiodes (Si-APD), a prototype photon counting lidar which used 8 APDs coupled with a 1×8-pixel fiber array has been made in June, 2011. The experiments with static objects showed that the photon counting lidar could operate in strong solar background with 0.04 receiving photoelectrons on average. Limited by less counting times in moving platforms, the probability of detection and the 3D imaging density would be lower than that in static platforms. In this paper, a latest fiber array coupled multi-channel photon counting, 3D imaging, airborne lidar system is introduced. The correlation range receiver algorithm of photon counting 3D imaging is improved for airborne signal photon events extraction and noise filter. The 3D imaging experiments in the helicopter shows that the false alarm rate is less than 6×10-7, and the correct rate is better than 99.9% with 4 received photoelectrons and 0.7MHz system noise on average.


This paper aims at analyzing and discussing the construction and expansion of Sao Paulo–Rio Grande Railroad (EFSPRG) in Santa Catarina. The text is divided into three topics. There is a brief introduction that analyzes the reasons for the railway expansion in the southern Brazil. In the sequence, the text studies the building of Santa Catarina's line in the tea plantation and wood exploration region, between Porto Uniao and the Uruguay River. Finally, the paper discusses the integration of the northern plateau through the line Porto Uniao–Sao Francisco do Sul. The first railway, in the middle west of Santa Catarina, was built between 1907 and 1910; the second railway, in the north plateau, was built between 1906 and 1917. Both railways were part of the fragmented railway system in Santa Catarina, which was concentrated in the exporting regions integrated by the ports, without an intra-regional integration.


Renewables have passed the peak of the inflated expectation hype cycle for emerging technologies, but interest in the design of new energy conversion devices is still high due to widespread distributed energy systems for private households. Magnus effect-based wind turbine combines mechanical and electronic engineering that provides a broader wind speed range and potential maximum power point tracking for deeper grid integration. This paper provides a comparative analysis of Magnus effect-based wind turbine simulation models and the development of the numerical model for the maximum power point tracking algorithm. The advanced model contributes to the reduction of the number of actual tests required for the mechatronics system tuning and deals with sustainability-related challenges, such as climate change and the development of new renewable sources of energy.


Substance abuse is increasingly recognized as a multi-faceted, complex and chronic problem that requires a comprehensive approach and ongoing support services. In this dissertation, we focused on the organisation and quality of substance abuse treatment in a clear-cut region (Ghent, Belgium) and on an alternative approach to optimise treatment and delivery of service for substance abusers.
First, various indicators of coordination and continuity of care were studied in the treatment agencies involved. Second, we focused on the implementation and evaluation of case management for substance abusers, based on systematic literature reviews. Third, two empirical studies were set up to evaluate the implementation and effectiveness of case management for substance abusers with multiple and complex problems. Finally, we assessed how this intervention could be implemented in the network of available services


This paper addresses time fractional Schrödinger equations using He's semi-inverse method. The (3 + 1)-dimensional time fractional Schrödinger equation and the time fractional unstable nonlinear Schrödinger equation are considered. 1-soliton solution is constructed for these two time fractional Schrödinger equations. In particular, the parameters' constraint conditions are also derived for the existance of solitons. The method is straightforward and concise for solving differential equations.


The main objective of this paper is to obtain explicit estimates on some integral inequalities on time scale. The obtained inequalities can be used as tools in the study of certain classes of dynamic equations on time scale.


We report on the multi-level-cell (MLC) operation of AND-connected ferroelectric FET (FeFET) arrays and their suitability for Compute-in-Memory (CiM) applications. The switching behavior and device variation of FeFETs in a passive AND array test-structure configuration is investigated. From this, we derive suitable write schemes and inhibit schemes capable of protecting any FeFET state. This enables the MLC operation of the AND arrays, yielding a performance suitable for CiM applications. We investigate the impact of the obtained bit-error-rate (BER) of 4% in inference-only operation, which shows only a 1% degradation from the floating-point (FP) accuracy for CIFAR-10 datasets with LeNET.


This paper deals with certain experiments carried out in the Mount Royal Tunnel of the Canadian National Railways at Montreal, Quebec, in order to determine how radio waves reach the receiving set. Preliminary experiments in 1926 indicated that the penetration of radio waves into the tunnel was a function of the frequency, short waves below 100 meters dying out within a few hundred feet of the mouth of the tunnel. More exact experiments and measurements were planned and carried out in 1928 to bring out the part played by the wires, cables, and rails leading into the tunnel. The tunnel mouths were blocked and the cables grounded, and the results so obtained indicated that the effect of cables and rails was also dependent on the frequency. It was also evident that more actual energy entered via the tunnel itself than was at first suspected. The effect of rails and cables is not a simple one but involves loop action, wave-antenna effects, and re-radiation. Curves are attached showing graphically the results obtained. A map of the area and an elevation of Mount Royal itself give general details of the geology of the region.


The study demonstrated that the non-Machiavellian layman, given a detailed description of the high Mach, can consistently produce a valid representation of highly manipulative interpersonal behaviour under instructions to respond to the Mach V "as a Machiavellian would". Simulation is thus shown to be a viable alternative to the median-split and extensive-testing methods for obtaining subjects for investigations of Machiavellianism, for reasons of veridicality and economy, respectively.


The dynamics of passenger aircraft on the ground are influenced by the nonlinear characteristics of several components, including geometric nonlinearities, the aerodynamics and interactions at the tyre-ground interface. We present a fully parametrised mathematical model of a typical passenger aircraft that includes all relevant nonlinear effects. The full equations of motion are derived from first principles in terms of forces and moments acting on a rigid airframe, and they include implementations of the local models of individual components. The overall model has been developed from and validated against an existing industry-tested SimMechanics model. The key advantage of the mathematical model is that it allows for comprehensive studies of solutions and their stability with methods from dynamical systems theory, in particular, the powerful tool of numerical continuation. As a concrete example, we present a bifurcation study of how fixed-radius turning solutions depend on the aircraft's steering angle and centre of gravity position. These results are represented in a compact form as surfaces of solutions, on which we identify regions of stable turning and regions of laterally unstable solutions. The boundaries between these regions are computed directly and they allow us to determine ranges of parameter values for safe operation. The robustness of these results under the variation of an additional parameter, specifically, the engine thrust is investigated. Qualitative changes in the structure of the solutions are identified and explained. Overall our results give new insight into the possible turning dynamics of the aircraft in dependence on three parameters of operational relevance.Copyright © 2009 by ASME


The invention relates to a dynamometer for an automobile chassis, aiming at solving the shortages that the existing dynamometer for the chassis has unstable detection data, low accuracy and poor reliability, is difficult to correctly evaluate the power performance of the vehicle and the like, and the defects that the dynamometer can not realize the compatibility of power performance detection function and emission inspection function. The invention provides a dynamometer for the automobile chassis, comprising a stander, an anti-drag motor, an eddy current machine, a force measurement sensor and a speed sensor arranged on the eddy current machine, and a pair of driving roller and driven roller linked to each other; two ends of the driving roller and the driven roller are rotatablely connected on the stander by a bearing respectively; the driving roller is connected with the eddy current machine and the anti-drag motor; and the force measurement sensor adopts a dual-range sensor. The invention provides a measurement and control method for the dynamometer used for the automobile chassis. The dynamometer for automobile chassis and the measurement and control method thereof have stable detection data, high accuracy and good reliability and can realize the compatibility of the power performance detection function and emission inspection function.


This paper proposes the development of a deep learning model for diagnosing COVID-19 through the analysis of chest X-ray images. First, data augmentation is implemented to avoid overfitting and improve model generalization. Then, instead of conventional image segmentation techniques, Gradient-weighted Class Activation Mapping (Grad-CAM) is used to highlight the important regions directly related to COVID-19. Subsequently, transfer learning is implemented to transform the data of the X-ray images to a reduced set of features using the Xception convolutional neural network. Finally, a classification neural network is designed, parameterized and trained, which is capable of recognizing healthy patients with 97% accuracy, while the detection rate for patients infected with COVID-19 was 92%.


Abstract Rationale Bedaquiline is a novel antimycobacterial agent for drug-resistant tuberculosis (DR-TB) and is classified as a World Health Organization (WHO) Group A drug due to its excellent clinical efficacy, high bactericidal activity, and potent sterilizing effect. Baseline and treatment-emergent bedaquiline resistance have been described but prevalence and incidence have not been reported, leading to gaps in the knowledge required to design strategies to optimize MDR-TB clinical outcomes and prevent the amplification of bedaquiline resistance. Methods We performed a systematic review and meta-analysis to estimate the frequency of, and mutations associated with, baseline and acquired (treatment-emergent) bedaquiline resistance in clinical Mtb isolates. Pooled estimates of bedaquiline resistance were generated by proportional meta-analysis in R version 4.2.2 using dmetar, metafor and meta packages. Resistance associated variants associated with prevalent and incident bedaquiline resistance were identified. Results Data from 14 studies were included; 14 and 9 studies reported on pre-treatment and acquired bedaquiline resistance, respectively. The pooled prevalence of pre-treatment bedaquiline resistance was 2.4% (95% CI 1.7 - 3.5), with significant heterogeneity across all studies (I2 66%, p<0.01). The pooled prevalence of treatment-emergent bedaquiline resistance was 2.1% (95% CI 1.4 - 3.0), with no significant heterogeneity across the included studies (I2 0%, p=0.97). Discussion We found a concerning frequency of bedaquiline resistance present at baseline and acquired during treatment. Urgent strategies are required to mitigate further resistance to this crucial drug.


Existing cognitive agent programming languages that are based on the BDI model employ logical representation and reasoning for implementing the beliefs of agents. In these programming languages, the beliefs are assumed to be certain, i.e. an implemented agent can believe a proposition or not. These programming languages fail to capture the underlying uncertainty of the agent's beliefs which is essential for many real world agent applications. We introduce Dempster-Shafer theory as a convenient method to model uncertainty in agent's beliefs. 1 Mapping agent beliefs to Dempster-Shafer sets In Dempster-Shafer theory[4], a frame of discernment Ω is defined as the set of all hypotheses in a certain domain. On the power set 2, a mass function m(X) is defined for every X ⊆ Ω, with m(X) ≥ 0 and ∑ X⊆Ω m(X) = 1. If there is no information available with respect to Ω, m(Ω) = 1, and m(X) = 0 for every subset of Ω. A simple support function is a special case of a mass function, where the evidence supports one set of hypotheses A, and zero mass value is assigned to any subset of Ω other than A. Mass functions can be combined using Dempster's Rule of Combination. This combination rule for mass function m1 and m2 is denoted as m1 ⊕ m2 and is defined, for X, Y, Z ⊆ Ω, as:


Most industrial Internet of Things (IoT) devices reduce the capture image size using high-ratio joint photographic experts group (JPEG) compression, saving storage space, and transmission bandwidth consumption. However, the resulting compression artifacts considerably affect the accuracy of subsequent tasks. Most artifact reduction algorithms do not consider the limitations of storage space and computing power of edge devices. In this study, a blind artifact reduction recurrent network (BARRN), which can reduce compression artifacts when the quality factors are unknown, is proposed. First, a structure based on recurrent convolution is designed for the specific requirements of industrial IoT image acquisition devices; the network can be scaled according to system resource constraints. Second, a more efficient convolution group, capable of adaptively processing different degradation levels, is proposed for optimal use of the limited computational resources. The experimental results demonstrate that the proposed BARRN can meet the needs of industrial systems with high computational efficiency.


Light pollution can disrupt animal health and behaviour; however, its effects on aquatic invertebrates are poorly understood. We found that unnatural light at night had no effect on heart rate or activity in Caribbean spiny lobster, suggesting this species and its fisheries may be somewhat resilient to light pollution.


This internationally acclaimed textbook is widely used for teaching basic SPC, Data Analysis, and Continual No longer all the first point for control a bit odd that they. What you use and transparent reports of total quality. Of acquisition were no such evaluations should be using the original. Data available is systematically happening, again from considerations based on the capability to day. And which are as the normal distribution actually! Spc may be provided by the review.


PSEE, SDE, workflow, process management, distributed systems The evolution of distributed object architectures (mainly COM, CORBA and Java) opens an unprecedented range of possibilities in terms of automatic process management and PCEs (process-centered environments) play a key role in the software process re-engineering induced by these technologies. The human factor is still the major component of the software process but, as complexity and precision requirements increase, its role is changing and so does the kind of support it needs.


You might be forgiven if you have never noticed the Pioneer Palace in Moscow 's Lenin or, formerly, Sparrow Hills (figure 1). You may have dismissed it as ju st anotherof those postwar prefabs that reminds you of your high school. Or perhaps you were too busy looking at Stalin's Moscow University, which looms over it. Yet, when the Pioneer Palace was built between 1958 and 1962, at theheight oftheKhrushchevThaw,thismodernistbox ofglass and reinforced concreteinspired enormousenthusiasm.


This study was carried out to investigate whether prina (olive cake) affects growth performance when given in diet or separately in choice feeding. Twenty four Awassi lambs were divided into three groups control, prina and choice. Control lambs were fed on lamb grower conteined 18% crude protein. Prina lambs were fed on a diet that 20% prina diluted concentrate feed including 20% crude protein. Choice lambs were offered a choice of concentrate feed and prina simultaneously. Treatments did not affect lambs growth performance negatively. Prina in concentrate and choice feeding increased ruminating behaviour without affecting animal health, suggesting that prina can be used in lamb nutrition to lower feed cost. However, lambs voluntarily consumed prina in smaller amout about 3.6% of diet, most likely due to its wooden content. © 2011 Friends Science Publishers


Emoticons such as (^_^) are face-shaped symbol sequences that are used to express emotions in text. However, the number of emoticons is miniscule. To increase the number of emoticons, we created emoticons using SeqGANs, which are generative adversarial networks for generating sequences. However, the small number of emoticons means that few emoticons can be used as training data for SeqGANs. This is concerning because as SeqGANs underfit small training data, generating emoticons using SeqGANs is difficult. To address this problem, we duplicate the training data. We observed that emoticons can be generated when the duplication magnification is of an appropriate value. However, as a trade-off, it was also observed that SeqGANs overfit the training data, i.e., they produce emoticons that are exactly the same as the training data.


FIELD: radio engineering, communication. SUBSTANCE: flexible display includes a sensor configured to detect bending of a flexible display, feedback support facility made with the possibility to provide a feedback according to the detected bending, and a controller adapted to control a feedback support facility to provide feedback, when the detected bending degree exceeds a threshold. EFFECT: providing with a feedback with a warning about the bending degree to avoid damage of the flexible device. 15 cl, 39 dwg


Theoretical calculations and some indirect observations show that massive exoplanets on tight orbits must decay due to tidal dissipation within their host stars. This orbital evolution could be observationally accessible through precise transit timing over a course of decades. The rate of planetary in-spiralling may not only help us to understand some aspects of evolution of planetary systems, but also can be used as a probe of the stellar internal structure. In this paper we present results of transit timing campaigns organised for a carefully selected sample of hot Jupiter-like planets which were found to be the best candidates for detecting planet-star tidal interactions on the Northern hemisphere. Among them, there is the WASP-12 system which is the best candidate for possessing an in-falling giant exoplanet. Our new observations support the scenario of orbital decay of WASP-12 b and allow us to refine its rate. The derived tidal quality parameter of the host star Q'_{*} = (1.82 +/- 0.32) x 10^5 is in agreement with theoretical predictions for subgiant stars. For the remaining systems - HAT-P-23, KELT-1, KELT-16, WASP-33, and WASP-103 - our transit timing data reveal no deviations from the constant-period models, hence constraints on the individual rates of orbital decay were placed. The tidal quality parameters of host stars in at least 4 systems - HAT-P-23, KELT-1, WASP-33, and WASP-103 - were found to be greater than the value reported for WASP-12. This is in line with the finding that those hosts are main sequence stars, for which efficiency of tidal dissipation is predicted to be relatively weak.


Microstructure and electrochemical properties of Ti0.4Zr0.1V1.1Mn0.5Ni0.4Crx(x=0,0.1,0.2,0.3)alloys have been investigated.Results of XRD and SEM-EDS analyses show that all alloys are composed of a major V-based solid solution phase with body-centered-cubic structure and a minor C14Laves phase with hexagonal structure.The V-based solid solution phase appears as dendrite with C14Laves phase precipitating along its grain boundary,forming a three-dimensional network.Effect of Cr addition on the electrochemical properties of Ti0.4Zr0.1V1.1Mn0.5Ni0.4Crx(x=0,0.1,0.2,0.3)alloys was studied by electrochemical method.With increasing Cr content from x=0to x=3,the maximum discharge capacities of Ti0.4Zr0.1V1.1Mn0.5Ni0.4Crx(x=0,0.1,0.2,0.3)alloy electrodes at 303Kare 574.6mAh/g,418.8mAh/g,368.8mAh/g and 322.9 mAh/g,respectively.It is emphasized that high discharge capacity of 824.1mAh/g is obtained at x=0at 333K.The addition of Cr noticeably improves the high rate discharge performance and durability of alloy electrodes.The capacity retain rate of 62.3%is attained at x=3after 40charge-discharge cycling.Among the alloys studied,Ti0.4Zr0.1V1.1Mn0.5Ni0.4Cr0.1 alloy has the best overall electrochemical performance.


Level control valve for the tank of a motor vehicle - one arranged inside a tank and the end of a filling pipe forming the tubular casing (1), - a movably mounted on the housing (1) float (2), and - a to the float (2) coupled for movement and from this one between the internal cross section of the housing (1) shut-off closed position and an open position releasing these movable closing element (5), characterized, that the closing element (5) is guided in a direction of the central longitudinal axis (3) of the housing (2) body, which cooperates in the closed position with its peripheral surface with the inner housing wall in the sense of a sealing pairing.


Over the past two decades synchrotron facilities dedicated to the generation of x-rays for study of atoms, molecules and condensed matter have proliferated all over the world. As a result of the special properties of x-rays produced by these machines, there has been an enormous growth in the experimental possibilities. In this work we will demonstrate how these special properties can be used to carry out hitherto impossible measurements of the Angstrom level structure of the free surfaces of liquids. We demonstrate that surface structure of liquids is often different from that of the bulk.
A large part of this thesis is devoted to surface-induced atomic or molecular layering phenomenon in metallic and dielectric liquids. In Chapters 1 through 10 we describe surface features of high-surface tension metals (Ga, In, Hg, Sn), as well as alkali metals (K, KNa) and water. The second part of the thesis (Chapters 11 through 16) is devoted to surface of binary metallic alloys (GaIn, HgAu, KNa, BiIn and GaBi), investigating a wide range of surface phenomena such as Gibbs adsorption and the tetra-point nanoscale wetting.


Scientific knowledge as necessary false consciousness is a critique of science. Such criticism is underlined under two propositions: that it needs to come theoretically, and that it must express a situation under conflict. On the first aspect, the concepts of first nature, second nature and necessary false consciousness are developed in order to ilustrate, on the second aspect, how science is enframed: as part of the material needs of the second nature but justified on the basis of the human/nature relationship in the first nature.


Two previous papers by Neal, Schneiter, and Caminita (17, 20) have presented conclusive evidence that outbreaks of acute illness among workers using low-grade stained cotton were due to an endotoxic substance produced by a Gram-negative, rod-shaped microorganism present in large numbers in and on the cotton fibers. The organism was tentatively classed in the genus Aerobacter and, for convenience, it was referred to as the "cotton bacterium." The clinical syndrome of the acute illhiess described closely resembled that of mill fever reported among cotton mill operatives and hemp fever and grain fever reported among hemp plant workers and grain handlers, respectively. Therefore, samples of cotton mill dust, hemp mill dust, and grain elevator dust were examined and cultures of microorganisms identical with those isolated from the stained cotton were obtained. This paper presents the results of taxonomic studies OD cultures of the "cotton bacterium" isolated from various sources.


In the Middle Miocene (approximately 17 to 12 Ma) at least two radiations of fossil apes from East Africa into Eurasia occurred, and, while controversial, some paleoanthropological studies suggest that one of the Eurasian lineages may have returned to Africa to evolve into humans and the African apes. Here, we present a novel argument supporting this hypothesis. Specifically, the global cooling that occurred in the middle Miocene rendered hominoids living in Europe at risk for starvation as seasonal climate change resulted in less availability of fruits during the winter months. During this time, a mutation in uricase occurred in early hominids that resulted in a rise in serum uric acid. Uric acid has been found to potentiate the effect of fructose to increase fat stores, suggesting that the mutation provided a survival advantage. Such a survival advantage would have been less likely to occur in Africa, where the continued presence of tropical rainforests would have been more likely to provide food throughout the year. Furthermore, Miocene apes in Europe were in protected sites where geographic isolation could have allowed the uricase mutation to be rapidly expressed in the entire population. While speculative, we suggest that the uricase mutation supports an extra‐Africa origin of humans.


Onboard energy storage system (ESS) is an important energy-saving technology in urban rail transit. The key issue of the ESS is the array configuration. In this paper, a new array configuration methodology is developed. First, the limitations of the capacity-constrained configuration method, which is mainly adopted for configuring the onboard supercapacitor array (OSA), are investigated. Second, a mathematical model of the OSA is developed taking into account power and capacity constraints so that the absorbed braking energy can be recovered. Finally, a powerand capacity-constrained configuration methodology (P&C-Method) is proposed. Digital simulation studies are conducted, and the results show that the OSA with the proposed P&C-Method can realize the effective energy recovery of the whole absorbed braking energy and have a high energy-saving effect/weight ratio.


The ecological footprint is a signal or indicator to measure the effects of man's activities on the environment, and therefore it is considered a bell to the extent of human impact on the environment and depletion of its resources. As cities are the container that contains these activities and are the direct drain of environmental resources, that valuable tool should be adopted (ecological footprint) to measure environmental resources consumption in cities. Therefore, the research focuses on simulating the method of ecological footprint to measure the sustainability of cities by finding equations to calculate the ecological footprint of the city components to give the overall value of the urban footprint; this means that the impact of urban areas on the environment is calculated. Therefore, the research aims at accessing the tools of new equations to calculate the urban footprint of each sector of the city to identify its impact on the environmental resource's consumption and identify the imbalance or shortage of resources consumption accurately as well as to identify the city possibilities. Thus, that gives the opportunity to take the necessary measurements to deal with them.


AT the beginning of the third part of the Theaetetus (201d–2O2c), Socrates entertains an interesting theory of knowledge in the form of a 'dream'. In Cornford's translation, it reads as follows: I seem to have heard some people say that what might be called the first elements () of which we and all other things consist are such that no account () can be given of them. Each of them just by itself can only be named; we cannot attribute to it anything further or say that it exists or does not exist; for we should at once be attaching to it existence or nonexistence, whereas we ought to add nothing if we are to express just it alone. We ought not even to add 'just' or 'it' ('that') or 'each' or 'alone' or 'this', or any other of a host of such terms.


Recent concerns about the risks associated with rosiglitazone (a thiazolidinedione) have increased interest in the safety and efficacy of all oral agents for type 2 diabetes. Researchers recently reviewed the literature to summarize the risks and benefits of these drugs; they identified 216 controlled trials and cohort studies and two systematic …


The Kibble balance will be one of the major instruments in the future for realizing the unit of mass, kilogram, in the new international system of units (SI). A recent experimental study at the Kibble balance group at the Bureau international des poids et mesures (BIPM) showed that the magnetic profile measured in weighing and velocity phases is sloped differently due to the movement of the current-carrying coil. This phenomenon has been explained by an analysis of the coil inductance energy (weighing) and self-induction (velocity). In this paper, the magnetic field change at the coil position due to the current is analyzed, in which the slope difference can be well integrated.


Suicide is one of the most threatening problems in the hospital management of schizophrenic patients and yet surprisingly little information can be found in the current psychiatric writings about the psychopathological basis of the self-destructive drive or about the types of patients who are likely to attempt suicide and under what circumstances. Even the base-line epidemiological data are scarce. The available reports of the incidence or prevalence of suicidal acts are not comparable because the definitions are not uniform. While some authors deal only with completed suicides, most investigators focus on suicidal risk as clinically more useful information. Thus Jantt (1951) analyzed the cases of 138 suicidal patients obtained from a sample of 1000 schizophrenics admitted to the university clinic at Freiburg in the years 1940-1948, considering as suicidal risk cases those patients who had serious suicidal preoccupations or made an actual attempt at some time during the psychosis. The suicidal risk rate was, of course, 13.8 %, Rizto (1957) examined case histories of 1173 schizophrenics treated at the mental hospital of the Venice district in the years 19461955. Fifty-two patients, i. e. 4.4 %, either tried to kill themselves or made unsuccessful preparations. In a Swedish sample of 138 schizophrenic men, Johanson (1958) found 11 patients who tried but failed and 3 who succeeded. Achte' ( 1961) compared schizophrenics admitted to Helsinki hospitals in the 1930's with those admitted in the 1950's. A marked increase in suicidal attempts was noted, from 13 "/o in the thirties to 2 2 % in the more recent group. Because of this dearth of information we made a survey of the case histories of the suicidal male schizophrenics, focused mainly on the characteristics of the illnesses of the suicidal patients relevant to the daily hospital care,


We discuss the polarized photon structure function and focus on the first moment of , where we explore the role of the axial QED and strong U(1) anomalies. Electromagnetic gauge invariance determines an exact sum rule for the first moment of . If we accept a recently proposed definition of "spin content" then we must also accept a polarized gluon component of Δgγ=2π/αs in the spin-one photon.


Currently, numerous (broadcasting) programs are being provided to viewers, which makes it hard for viewers to select a program to watch. Especially, surfing channels watching the program videos (which is the most general manner of searching a program) became a time consuming task of performing several tens of channel changes (a channel change takes about 0.7 second). In the paper, a data service for guiding programs using the multi-view of program videos is proposed. The data service allows viewers to navigate all program videos without channel changes. To implement the data service, a method for composing and transmitting multi-view videos with the meta data for handling each video of the multi-view has been devised and a Java API has been implemented to clip, resize, and display parts of the multi-view videos.


Imposition of a partial factor tax (the most common example of which is a corporation income tax) will impose an excess burden on society. That excess burden implies a reduction in consumers' real income above and beyond the tax transfer to the government. The incidence of the tax depends, in part, on the way consumers react to that real income loss. In this paper we show that omission of this effect, as occurs in the well-known Harberger model, will bias results toward the conclusion that capitalists bear the tax burden when the corporate sector is labor intensive.


Summary EGF and HB-EGF play crucial roles in embryonic development and peri-implantation. In this study, aim was to characterize expression profiles of EGF and HB-EGF in mare endometrium during estrous cycle and early pregnancy. Endometrium biopsies were obtained from mares on day of ovulation (d0), late diestrus (LD) and after luteolysis (AL) in the estrus phase. In pregnant groups, biopsies were taken on days 14 (P14), 18 (P18), 22 (P22) and 60 (P60). Relative expression levels of genes were quantified using real-time RT-PCR. A mixed model was fitted on the normalized data and Least Significant Difference (LSD) test was employed to determine significantly different group(s). EGF mRNA expression was up-regulated at LD compared to d0 while HB-EGF expression was not changed throughout the cycle. EGF expression was also increased during early pregnancy with the highest expression level observed on P60. Similarly, HB-EGF mRNA level was increased on P60. Pregnancy induced EGF expression on P14 and P18 compared to LD and AL whereas expression of HB-EGF was only significantly higher on P18 than that of AL. These results indicate that EGF expression is up-regulated during the cycle at late diestrus when P4 is high and is increased by pregnancy. HB-EGF expression is induced later in the pregnancy. In conclusion, EGF and HB-EGF appear to involve in the events that happen in the mare endometrium during peri-implantation period.


Defined by the simplest parameters - colour and shape - yet voluminous in possibility, the little black dress is personalised by the designer who imagined it and the woman who wears it. This volume presents a timeless anthology, with each dress included in the show and catalogue an eloquent translation of an enduring icon.


Objective: With increasing pressure for accountability in the Australian health service, clinicians require reliable and valid measurement tools for assessing the physical status of stroke patients in the acute setting prior to entering rehabilitation, so that predictions can be made about the potential length of stay in rehabilitation and level of outcome. In response to the lack of suitable measures of physical disability for acute stroke patients, the Mobility Scale for Acute Stroke Patients was developed. The aim of this paper was to investigate the intra-rater and inter-rater reliability of the scale. Method: Five tasks, which incorporate functional movements from lying to walking, were assessed using a six-point scale based on the level of assis tance. Stroke patients were filmed while being assessed by an experienced examiner using the Mobility Scale. Twenty-one clinicians viewed 10 video- taped performances of each activity. Results: The intra-rater reliability from the viewing sessions one month apart was excellent for 92% of the judgements (weighted kappa >0.75). The weighted kappa values for inter-rater reliability were all in the excellent agreement range above 0.75. Conclusion: The results of this study showed that the Mobility Scale has a high degree of reliability using this testing procedure. The reliability of the Mobility Scale in the clinical setting and its validity in predicting length of stay and outcome are being investigated.


ABSTRACT The article follows the evolution of administrative discourse on the identification of people in Martinique after the abolition of slavery. Censuses, internal passports, workers' booklets and immigration cards provide a specific perspective from which to study the connections between labour, mobility and the construction of 'race'. Beyond their apparent neutrality, these technologies drive vast governmental projects. Drawing on archive materials, the article tracks the ambitions, limits and social conflicts which characterized the politics of identification between 1852 and 1880. The interlocking histories of internal mobility and international migration are considered from the standpoint of identification practices, showing their relevance for the understanding of notions of 'citizenship' and of 'assimilation'.


In an open-label clinical trial, Jabbari and colleagues demonstrated clinical efficacy of the small molecule JAK1,3 inhibitor tofacitinib in 12 patients with moderate-to-severe alopecia areata (AA), a disease that results from autoimmune attack on the hair follicles with resulting significant hair loss. Tofacitinib, which has previously been approved for treatment of rheumatoid arthritis, halted hair loss and allowed considerable regrowth in 11 of these patients without serious adverse effects. Although the therapy is non-curative, as evidenced by relapse after treatment cessation, tofacitinib is a promising therapy for the treatment of hair loss in AA.


The Spanish Civil War occurred at a time when the British navy considered itself insufficiently strong to fight Italy in the Mediterranean while defending Britain's widespread empire. Italy was rearming and resented Britain's refusal to consider Italian rights in the Mediterranean or to recognize its conquest of Abyssinia. The Spanish Civil War gave Italy the chance to support a right‐wing regime which would comply with the Italian interests in the Mediterranean, to challenge the security of British and French sea routes, and to inflict damage on British power and prestige. Though Britain in the end did not permit the Italian navy to dominate the entire Mediterranean, it could not prevent the risk of dominance in the western part. The sea route to Republican Spain became increasingly hazardous and by 1938 the Spanish Republic was effectively blocked, which was an important factor in its defeat.


А concept of self-development for information computer ecosystem that repeats evolution of human functionalities is offered. Novel high-speed multiprocessor based processes models for the associative logic information analysis in n-dimensional vector discrete space are proposed. The use of vector logic algebra for the creating processes models of real world problems is considered. At that the decision quality is evaluated by the proposed integrated non-arithmetic metrics of associative structures interaction.


In response to the needs of the market place for turbines in the 5000 to 6000 hp class, Solar Turbines Incorporated has responded with an uprate of their Centaur engine. Discussed in this paper are the features of the uprated engine, the Development Plan and the methodology for incorporating into the design the advanced aerodynamic and mechanical technology of the Mars engine. The Mars engine is a high efficiency 12,500 hp engine which operates at a turbine inlet temperature of 1935°F. State-of-the-art computer aided methods have been applied to produce the design, and the results from this approach are displayed.Copyright © 1985 by ASME


Mobile Internet technology is evolved from the combination of mobile communication technology and Internet technology; in recent years,with the development of the mobile communication technology and the rapid growth in the number of users,mobile Internet technology has been constantly advancing and therefore enabled this technology to be used for various new applications. Traditionally,mobile Internet technology is utilized as a tool for business promotion for industry members. On the other hand,it can also help restructure the business model,providing a contemporary approach for information delivery,traffic data acquisition analysis,mobile data transmission and vehicular communication systems. Mobile Internet technology will have a profound influence on the management of Expressways.


Abstract We investigate the Marangoni instability in a thin polymeric liquid film heated from the free surface. The polymeric solutions are usually a binary mixture of a Newtonian solvent with a polymeric solute, and exhibit viscoelastic behaviour. In the presence of a temperature gradient, stratification of these solutes can take place via the Soret effect, giving rise to the solutocapillary effect at the free surface. Considering this cross-diffusive effect and incorporating the effects of gravity, here we analyse the stability characteristics of this polymeric film when bounded between its deformable free surface and a poorly conductive rigid substrate. Linear stability analysis around the quiescent base state reveals that, under the combined influences of thermosolutocapillarity and the elasticity of the liquid, apart from the monotonic disturbances, two different oscillatory instabilities can emerge in this system. The characteristics of each instability mode are discussed, and a complete stability picture is perceived in terms of the phase diagrams, identifying the model parameter regimes for which a particular instability mode becomes dominant.


The article deals with the concepts of innovation and innovation processes in agriculture, provides f classification of the types of innovations. It suggests ways to enhance innovation activity in the agriculture sector of the Russian Federation.


"Since 1958, the most significant change that has marked the gap between the text of the Constitution of the Fifth Republic and French political life over the past decade is, undoubtedly the ""growing role"" of the judiciary in French society. Any democracy of opinion is, by definition, based on the adherence of the citizens to a form of social truth. Beyond the assertion of a political or legal truth, it now also requires a judicial truth. Although the role of the judiciary in society has changed, such is not the case with its written constitutional status, i.e., its place within the State. A constitution is first and foremost a practice, and the most difficult reform is precisely to reorientate or to correct this practice. To restore the judiciary within the state means to restore mutual respect and confidence between the political and the judicial spheres. The fact that the three branches of power mutually control one another is only natural; it does not indicate any hierarchical superiority or any added legitimacy, be it political or judicial, elective, or constitutional; the three branches of power fullfill their roles and the people, as the only undisputed sovereign entity, decide in the last resort. Such is the challenge facing the campaigning constitutionalist: firstly, while sustaining liberty, endeavor to not give too much power to the judiciary and secondly, while upholding equality, endeavor to ensure that no one is shielded from justice."


THE DEVELOPMENT AND APPLICATIONS OF THE HINT SCORING FUNCTION: EXPLORING COLCHICINE-SITE ANTICANCER AGENTS AND TAUTOMERISM By Chenxiao Da, B.Eng., Ph.D. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University 2013 Advisor: GLEN EUGENE KELLOGG, Ph. D. ASSOCIATE PROFESSOR, DEPARTMENT OF MEDICINAL CHEMISTRY & INSTITUTE FOR STRUCTURAL BIOLOGY AND DRUG DISCOVERY


are present in Saccharomyces cerevisiae. In fact, Fogel et al.2) has cloned the gene for copper thioneine and showed hat copper-resistant yeast cells3) had the gene in multiple, tandemly amplified copies. Wehave identified the genes enhancing the resistance of Saccharomyces cerevisiae to zinc and cadmium ions and found that the regulation of the expression of the gene enhancing zinc resistance was different from that of the gene enhancing cadmium resistance. In this paper, we describe the phenotypic characteristics of the genes enancing the resistance of yeast cells to zinc and cadmium. The strains used were Saccharomyces cerevisiae DKD5D-H {a leu2-3 Ieu2-112 trpl his3), which was from Dr. Y. Oshima, and Escherichia coli C600 (F+ leu thr thi lacY supE tonA hsdS (r^, m^)), which was from Dr. M. Takanami. Media used for S. cerevisiae DKD-5D-H cultivation were YPD (2.0% glucose, 1.0% yeast extract, 2.0% peptone, pH 5.5) and SD (2.0% glucose, 0.67% yeast nitrogen base without amino acids, 20/ig/ml leucine, 20/ig/ml tryptophan, 20/ig/ml histidine, pH 5.5). Cultivation was at 30°C. E. coli C600 cells were cultivated in L-broth (0.1% glucose, 0.5% yeast extract, 1.0% peptone, 0.5% NaCl, pH 7.2) at 37°C. Chromosomal DNA of S. cerevisiae DKD-5D-H was isolated by the method of Saito and Miura4) and was digested with the restriction endonuclease Sau 3AI. The vector plasmid YEpl35) was


Introduction Guidelines recommend endoscopic variceal screening and surveillance in patients with cirrhosis.1 The rate of development of large oesophageal varices needing treatment appears to be 7–8% per year.2,3 However, with a growing proportion of diagnoses also now being made by Fibroscan we hypothesize that this rate may be lower. Methods We performed a case note review of 304 patients with a liver stiffness measurement (LSM) more than 15 kPa on Fibroscan between April 2012 and February 2016. Patients also had to have an endoscopy within 6 months to be included. We excluded patients with previous decompensation, hepatocellular carcinoma, inaccurate LSM (IQR >30%) or LSM felt to be aberrant by the clinician based on clinical, radiological or histological grounds. For patients with hepatitis C (HCV) we used post-SVR LSM. We recorded sex, age, aetiology of liver disease, LSM, platelet count, endoscopic findings at 0–6 months and at 24–48 months, duration of follow-up, incidence of bleeding or death. Varices were documented as absent, small or large. Results 113 patients were included. The most common aetiologies were non-alcoholic fatty liver disease (36.2%), alcoholic liver disease (29.3%) and HCV (20.7%). Mean age was 59.3 ± 11.5 years. LSM was 33.4 ± 17.1 kPa. Median follow-up was 4 years. Baseline endoscopy revealed no varices in 76 patients (67.3%), small varices in 29 patients (25.7%) and large varices in 8 patients (7.1%). 6 of the patients (5.3%) had a variceal bleed within 12 months. All large varices underwent band ligation (VBL) as per local practice. 58 patients went on to have a repeat endoscopy at 24–48 months. There was no progression of absent/small varices in 50 patients (86.2%) and a static gastric varix in 1 patient (1.7%). There was progression to large varices in 7 patients (13.8%) including 1 variceal haemorrhage. Conclusions In our group of patients with compensated cirrhosis the rate of development of clinically significant varices over 3 years appears to be lower than previous estimates. Weaknesses of the study include its retrospective nature and drop out rate. However, the findings would fit with our perception of an increased rate of diagnosis of advanced chronic liver disease by Fibroscan. The natural history of varices may be different to historic populations diagnosed on histological grounds or overt clinical and radiological features. References U.K. Guidelines on the Management of Variceal Haemorrhage in Cirrhotic Patients, Gut ( 2015) 64(11) 1680–1704 R Groszmann, G Garcia-Tsao, J Boschet al, Beta-blockers to prevent gastroesophageal varices in patients with cirrhosis, NEJM ( 2005) 353(21) 2254–2261 M Merli, G Nicolini, S Angeloniet al, Incidence and natural history of small esophageal varices in cirrhotic patients, J Hepatol. ( 2003) 38(3) 266–272


The goal of this work was to understand the direction of the emerging web technologies and to evaluate their expected impact on satellite networking.


Because of their unique properties redox flow batteries are promising candidates to meet the increasing demand for energy storage solutions resulting from the increasing use of fluctuating renewable energy sources. Because of the relatively high cost of the energy converter, in particular the electrode materials and the ion conducting membrane, research to improve energy efficiency and power density has been carried out. To compensate NAFION®, the anion-conducting membrane FAP was investigated, which can achieve the same performance as NAFION® but is porous. The performance of graphite felts shows a clear dependence on the type of thermal hydrophilisation. Cells using natural graphite as an electrode material have a lower internal resistance and higher reactivity than those with graphite composite electrodes.


Interview with professor Staffan Selander, who has contributed in important ways to the shaping of the field Designs for Learning.


Signal transduction is the process by which a cell converts one kind of signal or stimulus into another. In this process, G-protein coupled receptors (GPCRs) are considered a major class of membrane protein receptors. GPCRs play a critical role in signal transduction, and they are important pharmacological drug targets. Motivated by some specific experimental data, we construct a mathematical model to investigate a signaling system of interest. The model is composed of mass-action ordinary differential equations that describe ligand-receptor and receptorG-protein interactions. Because the kinetic reaction rates in the signaling processes previously gathered in reliable in vivo and in vitro experiments are limited to a small number of known values, we apply a genetic algorithm (GA) to estimate the parameter values in our model. In order to carry out the parameter estimation, we use the Augmented Lagrangian Genetic Algorithm (ALGA) with help from the mathematical theorem of infinite norm. This method ensures a faster parameter estimation speed in the modeled system. In addition, mathematical analyses are also performed. Some good agreement between analytic, numerical and experimental data was found. The simulation results of the model are extensively discussed and compared with the experimental data. ... G-PROTEIN COUPLED RECEPTOR SIGNAL TRANSDUCTION 19


Tanged points have long been considered an important proxy for cultural variability during the Incipient Jomon period of Japan. Historically, interpretations of cultural variability based on tanged points have relied entirely on studies of tang morphology. However, little attention has been paid to technological variation, which is a stronger indicator of culturally learned behavior than are morphological typologies. This paper describes ongoing research of flake scar orientation on tanged points produced by the oblique parallel pressure flaking (OPPF) technique from the Incipient Jomon. The results indicate that there is a highly significant, geographically patterned technological variation of such points. OPPF points from the south of Japan are exclusively flaked from the upper right to the lower left (URLL), while points from the north are almost always flaked from the upper left to the lower right (ULLR). Experimental research by the author and others suggests that this variation may indicate the adoption of different pressure flaking techniques in these two regions. If one considers the diversity of the flake scar patterns as an indicator of isochrestic variation in the Incipient Jomon period, the people of both regions appear to have had different culturally conditioned techniques of pressure flaking. This suggests that they did not adopt the same traditional rules concerning pressure flaking, nor did they have identical cultural behavior.


Abstract Our analysis of optical spectroscopy of high-mass X-ray binaries like Cyg X-1 confirms that most of the Balmer-lines emission anticorrelated with the X-ray flux originates from the circumstellar matter between the donor star and the accreting compact component. In order to study its structure and variability and the consequent accretion rate we have developed a 3-D numerical model based on radiation hydrodynamics of the supergiant stellar wind. The results show a non-stationary BHL-accretion on the compact component.


According to the principle of "high difficult teaching" that was put forward by the distinguished educator Zan Kefu.this paper puts forward that the technique of slip step is the first link in teaching, at the same time.it demonstrates by experiment and obtains the obvious teaching result.


Agribusiness is important to the global economy, but poor supply chain management can lead to losses and reduced customer satisfaction, which is why big data offers an opportunity to improve supply chain management in these sectors through big data-based technology models that focus on capturing, storing and analyzing big data to improve decision making in supply chain management. This big data improves communication and collaboration between the various players in the supply chain, resulting in better coordination and faster response to changing business requirements. Using real-time data and machine learning algorithms that can make better decisions and increase production and delivery efficiency. As a result, the technology model based on big data brings many benefits to supply chain management in the agri-food industry, such as product quality and transportation planning, accurate information, and time-based decisions, improving product quality and customer satisfaction. Concluding that this system can be applied in an optimal way, seeing that it is a system that generates a lot of costs, but in the future it is possible to see the adequate recovery periods.


An efficient Cu-catalyzed formation of tetra-substituted pyrazoles is reported. In this atom economic process, readily available enamines and nitriles are reacted by C–C and N–N bond formation. Oxygen has been successfully used as the oxidant, which has important economic and environmental advantages. A broad scope of enamines and nitriles can be utilized in this process.


T7 THNOGRAPHIC analogy has been widely used in archaeology to interpret Cj recovered data. Such analogy is actually a deductive test (evaluation) of an ethnoarchaeological model. The model or hypothesis consists of recorded behaviour and its material culture implications. If similar material culture implications are identified archaeologically, deductive reasoning leads to the conclusion that the behaviour was similar. The strength of such deductive conclusions can vary greatly, depending on (1) the number of confirmed implications, (2) the independence of the confirmed implications (the strength is greater with greater independence), and (3) the probability that all possible implications have been deduced and found to match (cf< LeBlanc, 1973).


This paper reports the dynamic viscosities of acetic acid + water, benzene, toluene, n-hexane and n-heptane at five temperatures in the range of 23 0 C to 46 0 C throughout the whole concentration range. The viscosity deviations were calculated from experimental data and fitted to a Redlich-Kister polynomial function. Results were analyzed in terms of molecular interactions.


The utility model discloses a self-adjusting outside rear-view mirror system. The self-adjusting outside rear-view mirror system comprises an automobile body controller, a left outside rear-view mirror, a right outside rear-view mirror, a stereo (ST) switch, a left turn signal lamp switch, a right turn signal lamp switch, a left horizontal plane regulation motor, a left vertical plane regulation motor, a right horizontal plane regulation motor and a right vertical plane regulation motor. The left horizontal plane regulation motor and the left vertical plane regulation motor are respectively connected with the left outside rear-view mirror, and the right horizontal plane regulation motor and the right vertical plane regulation motor are respectively connected with the right outside rear-view mirror. The self-adjusting outside rear-view mirror system can adjust the left outside rear-view mirror and the right outside rear-view mirror automatically when vehicles change lanes or overtake, solve dead zones existing in the rear-view mirrors, and avoid traffic accidents.


The temporal resolution of existing streak cameras are limited by electron transit time dispersion. Here we present a state-of-art design compensating this to achieve a breakthrough of 100fs time resolution.


The effects of molybdenum disilicide (MoSi2) and ferrophosphorus (FemPn) particles on the tribological properties of copper-tin bismuth (CuSn10Bi3) bimetallic bearing materials were studied in this paper. The samples of CuSn10Bi3 containing MoSi2 and/or FemPn were prepared by powder sintering technology and the metallographic structure of four kinds of self-lubricating copper alloy composite materials after sintering was observed. The tribological properties of the copper alloy composites under starved lubrication conditions were investigated and its worn surfaces and wear debris were discussed and analysed. The results show that the addition of MoSi2 and/or FemPn particles can effectively refine the grain size, optimise the grain boundary morphology, and improve the mechanical properties of the alloys. Under extreme working conditions, the hard particles reinforced copper-based alloy samples have better wear resistance and anti-seizure resistance. GRAPHICAL ABSTRACT


Africans represent a small but rapidly growing immigrant population in the United States. Nigerians, who constitute the largest group, form a well-organized community with numerous ethnic, hometown and social associations. Through some of these organizations, many Nigerians have successfully intervened in the economic and social development and the political processes of their hometowns. Their political involvement in the U.S. is less. In this article I use quantitative and qualitative data to analyze the motivations that Nigerian immigrants have for political involvement in Nigeria or the U.S., the means that enable this participation, and the constraints to participating. Findings suggest the importance of gender, class and acculturation for shaping political participation. The Transnational Political Involvement of Nigerian Immigrants in New York City 51


The problem of transferring the patients exists from prehistoric times. An adaptive technology known as wheelchair is used to deal with loss of mobility for the patients who are not able to walk normally due to some injury or some other age related walking disabilities permanent or under treatment, Later they were carried on wheels which reduced the effort of the person carrying the patients. Though we have evolved in the field of health care and technology we are not yet able to address this problem efficiently.
Mobility aids are used for carrying the patients. Wheelchairs, stretchers and walker are the most generally used mobility aids for the movement of patients. Transferring the patients from wheelchair to stretcher or else when they want to walk with the help of walker or to the medical bed or to stretcher is always an issue for the attendant or nurse. There is a wide range of wheelchairs available today driven by needs and desire of man.
Hence we suggest a design of wheelchair convertible stretcher and then to a walker which is a boon to the medical field. It would be maintained and operated easily either by the patient as per his wish of walking through walker or sitting on wheelchair or by sleeping on stretcher, by the attendant according to the comfort of the patient.


We suggest a nonparametric framework for unsupervised learning of projection models in terms of density estimation on quantized sample spaces. The objective is not to optimally reconstruct the data but instead the quantizer is chosen to optimally reconstruct the density of the data. For the resulting quantizing density estimator (QDE) we present a general method for parameter estimation and model selection. We show how projection sets which correspond to traditional unsupervised methods like vector quantization or PCA appear in the new framework. For a principal component quantizer we present results on synthetic and real-world data, which show that the QDE can improve the generalization of the kernel density estimator although its estimate is based on significantly lower-dimensional projection indices of the data.


Objective To investigate the expression of P53, PCNA protein and cell apoptosis in gastric carcinoma.Methods Flow cytometry and TUNEL were used to assay cell apoptosis and expression of P53, PCNA protein in 60 cases of gastric carcinoma.Results The ratio of apoptosis was significantly lower than that in paracancer tissue( 0.01), and the expression of P53, PCNA protein were much higher than those in paracancer tissue.The cell apoptosis was lower and fluorescent intensity was higher in the group of positive expression of P53.The expression of P53 and PCNA in low-differentiated gastric cancer were higher than those in well-differentiated type.The expression of P53 and PCNA in gastric cancer without lymph node metastasis was lower than those with lymph node metastasis.Conclusion Apoptosis is significantly inhibited in gastric carcinoma, and increased expression of P53 protein and proliferation may play an important role in the progression of gastric carcinoma.


This study aims to examine whether the pay gap between the chief executive officer (CEO) and non-executive employees affects the firm's research and development (R&D) efficiency.,The dependent variable is the firm's R&D efficiency, defined as a percentage increase in revenue from a 1-per cent increase in R&D spending. The main independent variable is the CEO-employee pay gap, defined as the ratio of annual total compensation for the CEO to the average of non-executive employees of the firm. The authors estimate fixed-effects models to examine the association between R&D efficiency and the pay gap between CEO and non-executive employees.,Results indicate a negative and significant association between R&D efficiency and CEO-employee pay gap, which suggests that a wider pay gap reduces employee motivation and effort, consistent with pay equity theory. We also find that the CEO-employee pay gap negatively moderates the relationship between employee pay growth and R&D efficiency,Recently enacted pay gap disclosure requirements mandated by the Dodd-Frank Act will make the disparity between CEO and non-executive compensation more salient. This study provides evidence of a firm outcome associated with that disparity.,This study is among the first to investigate the impact of the pay gap on R&D efficiency, a firm outcome not previously explored in the literature. This study also investigates CEO-employee pay gap's role as a factor that moderates the effects of employee pay growth and institutional ownership on R&D efficiency


In this paper we present the implementation of an advice-giving system for financial investment for the final phase of the project ESTEAM-316. This system integrates multiple agents in a single architecture allowing cooperation between a natural language dialoguer, "intelligent" data base access modules, and a problem solver in the financial domain. Using a user model, this system adapts the mixed initiative dialogue during both the formulation of the problem and its resolution by the expert. A novice user thus has access to expert knowledge despite the weakness of his own knowledge.


This presentation will explore several aspects of overteaching. The discussion will be framed by the three aspects of every course: content, pedagogy, and policies/procedures. For each of the three aspects, possible reasons why overteaching could occur will be explored along with methods to avoid doing too much for students.


Abstract In this paper we shall show that Weyl's theorem holds for class A(k) operators T where k≥>1, via its hyponormal transform $\skew3\hat{T}$. Next we shall prove some applications of Weyl's theorem on class A(k) operators.


We reformulate the problem of granular random close packing of 2D discs as a Quadratic Unconstrained Binary Optimization in order to utilize the D-Wave 2000Q quantum annealing computer. The solution is a set of ground states corresponding to jammed configurations in which no single particle can be moved without creating a non-zero potential. The problem is adapted to the quantum computer by discretizing space and mapping each point onto physical quantum-bits (qubits). An objective function is derived that defines the system energy for arbitrary particle locations, subject to constraints biasing solutions toward a pre-determined number of particles. Uniquely, the quantum computer samples and returns minimum values of this function finding low energy states, a subset of which are physically realizable solutions we seek. While quantum computing's technological infancy restricts our study to proofof-concept, our work still shows promise for efficient analysis of complex granular problems.


The setting of linseed oil under the influence of sulphur is more rapid than under the influence of air or heat, the setting point is more sharply defined and side-reactions occur less. An experiment is outlined where a specific amount of linseed oil and sulphur are mixed together and heated in a carbon dioxide environment. Samples were weighed, mixed with acetone and left for one hour. The supernatant acetone was poured off and the residue was dried. Results are tabulated with varying temperatures and sulphur amounts added. Oxygen was then bubbled through linseed oil, with no sulphur added and heated in a carbon dioxide environment. The results showed that with oxidised linseed oil, the proportion of acetone-insoluble polymerised material necessary for the occurrence of gelatin (gelatine), was smaller than with sulphurised linseed oil. When oleic acid was added, the polymerization of linseed oil under sulphur and heat's influence was not greatly affected.Molecular weights were determined for several acetone-soluble fractions, using benzene or camphor as a solvent. Concluding results are stated, including that acetone-insoluble liquid fractions of sulphurised oil are viscous, dark and set easily. Linseed oil sets harder and faster with more sulphur and heat added.


A hybrid quantum mechanical/molecular mechanics IMOMM (B3LYP:MM3) method has been applied to a series of five-coordinate 16-electron ML5 IrIII compounds having a relatively flat potential for a distortion from Y to T geometry and for which crystal structures have been obtained. In this series of type [Ir(biph)X(QPh3)2] (biph=biphenyl-2.2′-diyl; Q=P, X=Cl, 2a; Q=As, X=Cl, 2b; Q=P, X=I, 2c), the halide is found to lie in the (biph)Ir plane but off the C2 axis of the {Ir(biph)Q2} fragment by a variable angular distortion φ. While φ=0 is preferred electronically for [Ir(C4H4)Cl(PH3)2], the steric bulk of the real systems 2a–2c leads to φ taking experimental values of 8.2–17.2°. The observed deviation of the halide from the C2 axis is shown by IMOMM to be the result of a direct interaction of the phenyl substituents of the axial ligands with the equatorial ligands and not to an electronic effect. The crystal structures for 2b and 2c have been determined.


Although broadband photometry has been used to infer information about artificial satellites since soon after the launch of Sputnik 1, the development of photometric techniques for unresolved space object identification or characterisation has been hampered by the large number of variables involved. Many individual studies, and some long ongoing experiments, have used costly metre-class telescopes to obtain data despite other experiments demonstrating that much more flexible and affordable small aperture telescopes may be suitable for the task. In addition, due to the highly time consuming and weather dependent nature of obtaining photometric observations, many studies have suffered from limited data sets, or relied upon simulations to support their claims. With this in mind, an experiment was conducted with the aim of determining the utility of small aperture telescopes for conducting broadband multicolour photometry of satellites for the purpose of unresolved space object identification and characterisation. A 14 inch Celestron CG-14 telescope was used to gain multiple night-long, high temporal resolution data sets of six active geostationary satellites. The results of the experiment cast doubt on the efficacy of some of the previous approaches to obtaining and analysing photometric data. It was discovered that geostationary satellite lightcurves can vary to a greater degree than has generally been recognised, and colour ratios vary considerably with changes in the illumination/observation geometry, making it difficult to use colour for satellite discrimination. Evidence of variations in the spectral energy distribution of sunlight reflected off satellite surface materials was also obtained, which could have implications for surface material identification and techniques that aim to separate satellite body and solar panel contributions to the total observed spectra.


As laser interferometer gravitational wave (GW) detectors become quantum noise dominated, understanding the fundamental limit on measurement sensitivity imposed by quantum uncertainty is crucial to guide the search for further noise reduction. Recent efforts have included applying ideas from quantum information theory to GW detection -- specifically the quantum Cramer Rao bound, which is a minimum bound on error in parameter estimation using a quantum state and is determined by the state's quantum Fisher information (QFI) with respect to the parameter. Identifying the QFI requires knowing the interaction between the quantum measurement device and the signal, which was rigorously derived for GW interferometer detectors in [Phys. Rev. D 98, 124006]. In this paper, we calculate the QFI and fundamental quantum limit (FQL) for GW detection, and furthermore derive explicit reciprocity relations involving the QFI which summarize information exchange between the detector and a surrounding weak quantum GW field. Specifically, we show that the GW power radiation by the detector's quantum fluctuations are proportional to the QFI, and therefore inversely proportional to its FQL. Similarly, the detector's decoherence rate in a white noise GW bath can be explicitly related to the QFI/FQL. These relations are fundamental and appear generalizable to a broader class of quantum measurement systems.


For the few decades, the work on computer captured/scanned-skewed document image is a major challenge for the researchers in the field of OCR. Imaging the old historic or bulky book causes skewness and distortion on the image. The proposed metric retrieval method helps in preprocessing, skeletonization, skew detection, skew correction and recognition using horizontal and vertical text line extraction of the image. Text line detection depends on the goal of digitization. Digitization is helpful in museum and library where old historic and damaged manuscripts are imaged. In the real time the image is captured using the camera fitted in FPGA kit (cyclone II). The captured image is preprocessed with the verilog code which is converted from MATLAB code using simulink HDL coder.


66 Background: The American Society of Clinical Oncology (ASCO) Quality Oncology Practice Initiative (QOPI) has provided a method for measurement of process based practice quality since 2006. We sought to determine whether QOPI participants show improvement in measured quality over time, and if change is demonstrated, those factors in either the measures or participants which are associated with change.

METHODS
156 participant medical practice groups, which did not submit trainee data, participated in at least two collection rounds from 2006 through 2010, and reported on ≥30 patients per round from were included in analysis from a larger group of 306 participants from this time period. A database of these reports was used to evaluate trends in scoring among participants. A linear regression model, which controlled for varied initial performance, was used to estimate the effect of participation over time and evaluate participant and measure characteristics. Measures were aggregated into categories to evaluate which factors correlated with change.

RESULTS
Participants completed a mean of 5.71 (S.D. 1.84) rounds of data collection. Adjusted mean quality scores improved from 0.71 (95% C.I. 0.42 - 0.91) to 0.85 (95% C.I. 0.60 - 0.95). Overall odds ratio of improvement over time was 1.09 (p < 0.0001). The greatest improvement was seen in measures assessing newly introduced clinical information, where the mean scores improved from 0.05 (95% C.I. 0.01 - 0.17) to 0.69 (95% C.I. 0.33 - 0.91), (p ≤ 0.0001). Many measures showed no change over time.

CONCLUSIONS
QOPI has gained widespread adoption and approximately 15% of U.S. medical oncologists participate. Participation over time is highly correlated with improvement in measured performance. Much of this improvement is the result of the adoption of newly introduced clinical information. Some measures show no change despite significant opportunity for improvement.


.. Introduction: Opioid related side effects have encouraged the use of analgesic drugs that are devoid of these problems. Objective:This study was done to compare the analgesic efficacy of Ketorolac and diclofenac in 60 adult patients of age group ranging between 30 to 45 years of age body wt 50-60kg belonging to ASA I and II grade. Material and Methods: Patients were scheduled for elective gynecological procedure (laparoscopic tubal ligation) under general anaesthesia. They were divided into two equal groups using non-probability convenience sampling technique. Each group comprised of 30 patients. Group A received Ketorolac 10 mg I/V with local infiltration of 0.5% Bupivacaine and group B received IM Diclofenac sodium 75 mg after local infiltration 0.5% bupivacaine as in Group A 1⁄2 hourly before surgery. Post operatively patients were observed after 30 minutes in the recovery room for pain relief for two hours. Mean pain scores were noted in the recovery area using visual analog scale with need for supplementary analgesic after awakening from general anaesthesia. Vital signs were monitored. Result: Results were analyzed by using SPSS-8 package by applying Student Test and chi Square Test. There was statistically significant difference between two groups regarding their mean pain score. Conclusion: The patients who received Ketorolac I/V (Group A) had longer pain free time interval and request for first analgesic supplement was made after 90 minutes compared to a shorter interval of 60 minutes in Group-B, who received intramuscular diclofenac sodium.


Even superficial studies of the business career of John Jacob Astor emphasize its supposedly dualistic nature, and distinguish between the apparently sharply defined aspects of fortune-getting for which it stands. In fact, Astor's trading operations are frequently discussed as if they had not the slightest theoretical connection with his activities as an investor in land. It is the latter method of fortune-getting which is generally considered to afford exclusive opportunity for the appearance of an "unearned increment" (that is, gain of some sort, which cannot be attributed to the personal effort or personal ability of the beneficiary). Under the influence of this misconception, an attempt is made to distinguish between the profits arising from trade and the gains growing out of land investments on the ground that, in the one case, the size of the returns is conditioned by the degree of personal activity, whereas, in the other case, no appreciable amount of individual effort or ability is involved. Daniel Webster, for instance, in an address to the jury, when arguing against Astor's claim to lands in Putnam County, implied some such distinction between commercial exertions and land investments, in connection with the moral judgment that he passed upon Astor. True, his argument was impassioned and polemical in tone. Moreover, he was referring to a particular case of land investment characterized by certaini peculiar features. But the antithesis that he suggests is nevertheless significant-the more so, that it was designed to appeal to popular prejudices. His plea was that Astor had obtained possession of the land in dispute, not as he did that vast wealth than which no one envies him less than I do -not by fair and honest exertions in commercial enterprise, but by speculation, by purchasing up the forlorn hope of the heirs of a family driven from this country by a bill of attainder.'


The transport capacity of the railway system in BAOSTEEL was evaluated based on a thorough investigation on the carrying capacities of the sub systems, such as locomotive, arrival departure tracks, and loading unloading of products and coke. The investigation shows that the subsystems of locomotive and arrival departure tracks form the bottleneck of the railway system, the annual transportation capacities of which are 2.91 million t and 2.96 million t, respectively. Adding a locomotive and a arrival departure track will raise the annual carrying capacities of the two limiting subsystems to 4.39 million t and 3.56 million t, respectively, to meet the demands of carrying capacity by 2009.


CONTENTS I Introduction II The Trial: Towards More Efficient Proceedings III Issues of International Criminal Procedure A The Swiss Files B The Alibi Defence IV Individual Criminal Responsibility as a Superior V Applicable Law A Rape Constitutive of Genocide B The Crime of Conspiracy to Commit Genocide VI Conclusion I INTRODUCTION On 27 January 2000, Trial Chamber I ('Chamber') of the International Criminal Tribunal for Rwanda ('ICTR') (1) rendered its 'Judgement and Sentence' in Prosecutor v Musema ('Musema'). (2) Alfred Musema was found guilty of: genocide; (3) extermination constitutive of a crime against humanity; (4) and rape constitutive of a crime against humanity. (5) As punishment for these crimes, he was condemned to a single sentence of life imprisonment. (6) The ICTR, which was established on 8 November 1994 by Resolution 955 of the United Nations Security Council, (7) is mandated to prosecute and try persons responsible for serious violations of international criminal law committed in the territory of Rwanda and Rwandan citizens responsible for such violations committed in the territory of neighbouring States between 1 January 1994 and 31 December 1994. (8) Despite its broad mandate, due to logistical and financial constraints, the ICTR to date has restricted prosecutions to those persons considered to have the highest levels of responsibility for the massacres which occurred in Rwanda. From 1984 to 1994, Alfred Musema was the director of the Gisovu Tea Factory in the Rwandan Prefecture of Kibuye, (9) following appointment by Presidential decree. (10) Although a relatively new factory, by 1993 it was one of the more successful tea factories in Rwanda--its excellence being reflected in the London tea market. (11) In 1995, Alfred Musema was arrested in Switzerland. In 1996, he was charged by the Prosecutor for alleged violations of international criminal law on the premises of the Gisovu Tea Factory and in the surrounding hills. (12) The Prosecutor believed that Alfred Musema bore a high level of responsibility for these alleged violations, in part because his status as director of a successful tea factory in one of the poorest regions in Rwanda enabled him to exert substantial influence over the people he employed, and even over local authorities. (13) Moreover, according to the Prosecutor, Alfred Musema could not but have had strong links with the Government, even during the massacres. This is because tea was one of the main export earners in Rwanda, and the Gisovu Tea Factory was so economically successful. (14) Musema was the fourth judgment completed by the ICTR after a trial on the merits. (15) Although subject to appeal, (16) it is nevertheless illustrative of several issues of importance to the development of international criminal justice. First, as a result of greater judicial control of proceedings, the trial proved to be more expeditious than the previous three, and could thus indicate a new trend at the ICTR. Second, the trial of Alfred Musema highlighted some of the challenges to be met in the application of a constantly evolving international criminal procedure, which must seek, in particular, to bridge fundamental differences between the various legal traditions of the world. Third, the judgment lays an important--yet questionable--precedent, with Alfred Musema being convicted not only under the principle of 'direct' individual criminal responsibility, but also as a 'superior' (17) for acts committed by his subordinates. Finally, the judgment constitutes a landmark in the development of international criminal law, as it reiterates the jurisprudence concerning rape as an act of genocide, and also defines the elements of the offence of conspiracy to commit genocide. II THE TRIAL: TOWARDS MORE EFFICIENT PROCEEDINGS Alfred Musema was arrested on 11 February 1995 at the request of a Swiss examining magistrate (juge d'instruction). …


Abstract: The enzyme complement of two different mitochondrial preparations from adult rat brain has been studied. One population of mitochondria (synaptic) is prepared by the lysis of synaptosomes, the other (nonsynaptic or free) by separation from homogenates. These populations have been prepared from distinct regions of the brain: cortex, striatum, and pons and medulla oblongata. The following enzymes have been measured: pyruvate dehydrogenase (EC 184.108.40.206), citrate synthase (EC 126.96.36.199), NAD‐linked isocitrate dehydrogenase (EC 126.96.36.199), NADP‐linked isocitrate dehydrogenase (EC 188.8.131.52), fumarase (EC 220.127.116.11), NAD‐linked malate dehydrogenase (EC 184.108.40.206), D‐3‐hydroxybutyrate dehydrogenase (EC 220.127.116.11), and mitochondrially bound hexokinase (EC 18.104.22.168) and creatine kinase (EC 18.104.22.168). The nonsynaptic (free) mitochondria show higher enzyme specific activities in the regions studied than the corresponding values recorded for the synaptic mitochondria. The significance of these observations is discussed in the light of the different metabolic activities of the two populations of mitochondria and the compartmentation of the metabolic activities of the brain.


The purpose of this study was to investigate verifying the validity of three different exercise prescription programs following prevention of modem disease on girl students in the middle school. The subjects of the present study were fifteen female girl students. For the evaluation of exercise ability, maximal oxygen uptake was obtained from exercise stress test on a treadmill and paremeters of physical fitness including muscular strength, muscular endurance, power, agility, flexibility and balance were measured. According to the results, body fat levels was the lowest after 12weeks jogging program in A group compared to the B groups. However, control group was higher rather than that of other groups. In HDL-C levels was the highest after 12weeks jogging program in A group compared to the B group. However, control group was the lowest rather than that of other groups. Also, in TG and LDL-C levels was the lowest after 12weeks jogging program in A group than of the other groups. In physical fitness levels, back muscular strength and muscular endurance was only highest after 12weeks jogging program in A group compared to the other groups. Eventually, proper exerise prescription of exercise intensity, duration, time was appeared the effect of various types in blood and body composition factors following prevention of modem disease by experimental A group. Therefore further reseach needed in scientific method to study with proper diet method and exercise prescription.


Authenticated dictionaries (ADs) are a key building block of many cryptographic systems, such as transparency logs, distributed €le systems and cryptocurrencies. In this paper, we propose a new notion of cross-incremental proof (dis)aggregation for authenticated dictionaries, which enables aggregating multiple proofs with respect to di'erent dictionaries into a single, succinct proof. Importantly, this aggregation can be done incrementally and can be later reversed via disaggregation. We give an ecient authenticated dictionary construction from hidden-order groups that achieves cross-incremental (dis)aggregation. Our construction also supports updating digests, updating (cross-)aggregated proofs and precomputing all proofs eciently. 'is makes it ideal for stateless validation in cryptocurrencies with smart contracts. As an additional contribution, we give a second authenticated dictionary construction, which can be used in more malicious se‹ings where dictionary digests are adversarially-generated, but features only "one-hop" proof aggregation (with respect to the same digest). We add support for append-only proofs to this construction, which gives us an append-only authenticated dictionary (AAD) that can be used for transparency logs and, unlike previous AAD constructions, supports updating and aggregating proofs.


Two kinds of modified codewords for space–time block coded spatial modulation (STBC-SM) are presented in this study. The first modified codeword introduces a concept of flexible coefficients into the M-ary phase shift keying STBC-SM. A method is proposed to obtain the optimal flexible coefficients. Moreover, the first modified codewords can also be applied to the systems developed from the STBC-SM. In the second provided codewords, super-orthogonal space–time trellis codes are applied in STBC-SM. Therefore, a higher spectral efficiency is obtained compared with the original STBC-SM. Finally, the simulation results and theoretical analysis demonstrate these performance advantages of the two kinds of modified codewords for STBC-SM.


The Latin American debt crisis and the ongoing European debt crisis are quite similar with regard to the origin and development of the crises. In terms of the chronology of events, each crisis first started in a single country with bank-debt weakness and sovereign-debt exposure feeding on each other. Regional financial linkages caused the crisis in a single country to spill over, creating a cross-border liquidity episode. Finally, as the two sets of crises built on each other (cross-country and between sovereign and private sectors), creditors and debtors alike faced losses and, potentially, insolvency.


Review(s) of: The natural history of Sydney, by Dan Lunney, Pat Hutchings and Dieter Hochuli (eds.), Royal Zoological Society of New South Wales, Pp 438 + vi, ISBN 978-0-9803272-3-6, Price: Aud$75.00 (pbk).


Bird species diversity at Mount Nemrut (Adıyaman province, south-eastern Turkey) and in the surrounding areas was studied during the period 2009–2010. Data was collected using the point-count method at predefined observation sites. Birds of 107 different species were recorded, of which 20 were certainly breeding, 17 were probably breeding, and 29 were possibly breeding in the study area. Including species reported by other sources, a total of 160 bird species has so far been detected in the Mount Nemrut area, while the white-throated dipper was recorded for the first time. Diversity was calculated by using the Shannon-Wiener diversity index. Highest diversities were detected in woodland habitats (including oak groves), rocky areas and woodland habitats. Bird diversity showed peaks corresponding to spring and autumn passage migrations, and bird numbers were highest in mid-winter. Although part of Mount Nemrut has been declared one of Turkey's key biodiversity areas and has already been given the status of a National Park, threats occur, notably the harmful effects of mass tourism and illegal hunting, because of ineffective protection measures. Better knowledge of local avifauna and its habitat requirements may help to ensure better protection of this unique area. Research eco.mont – Volume 10, Number 1, January 2018 ISSN 2073-106X pr int vers ion – ISSN 2073-1558 onl ine vers ion: ht tp://epub.oeaw.ac.at/eco.mont ht tps://dx.doi.org/10.1553/eco.mont-10-1s36 36


New nonfouling tubes are developed and their influence on the adhesion of neuroproteins is studied. The biomarkers are considered as single components (recombinant prion and Tau proteins) or in a solution of native and pathological forms. The samples are stored for 24 h at 4 °C in virgin and treated tubes layered with two different nanostructured coatings based on poly(N-isopropylacrylamide) with either a positive or a neutral charge, and the protein adhesion is monitored. The recombinant protein with a high pI is repelled from the nanostructured surface that has a negative ζ potential, whereas the recombinant protein with the lower pI is attracted. Furthermore, in the case of complex solutions, neutral nanostructured surfaces are able to retain all amyloid biomarkers.


Trustworthy requirements analysis and selection of Software is an important part of trustworthy software research. Our paper based on the view of interdependency entity between FR and TS. By means of establishment of Trustworthy evaluation index system, analysis of goal-oriented requirements, trapezoidal fuzzy number evaluation model, we proposed a requirements selection method based on trustworthy constraints.


With the development of mobile technologies, more and more data and program running in the mobile environment, due to the instability of the mobile environment, safety and low, which makes the user's sensitive information can easily be leaked. The paper for the study of mobile database privacy issues, considering the special circumstances in the mobile computing mobile database its operational characteristics, presented a view of the combination model based on data services. Meanwhile, the management of multiple database view created by combining research, aimed at reducing the data while ensuring secure access to private data, the user permissions are combined as the final privacy threshold defined to ensure that the combined view of the plurality of conceal privacy related data items out.


Background and Aims: Patient cooperation, sedation, anxiolysis, and topicalization are important prerequisites for the successful and safe conduct of awake intubation. Because of the pharmacological properties, opioids can facilitate this process. Fentanyl is an opioid agonist and nalbuphine is an agonist-antagonist. This study aims to compare these two opioids for their effect on sedation and intubating conditions during awake fiberoptic intubation. Material and Methods: This randomized double-blind controlled study was conducted on 62 ASA I/II patients of either sex between the age of 20 and 60 years, weight between 40 and 80 kg, with MP class I/II airways requiring general anesthesia with endotracheal intubation. All patients received standard airway topicalization and nebulization. Patients were randomly allocated to one of the two groups according to a computer-generated random number table. Group F (n = 31) received fentanyl 2 μg/kg i.v. and group N (n = 31) received nalbuphine 0.2 mg/kg i.v. over 10 min before intubation. Fiberoptic intubation was attempted and lignocaine spray and propofol boluses were administered as and when required. Hemodynamic responses and intubating conditions were recorded. Repeated measure ANOVA, McNemar test, and Chi-square test or Fischer's exact test were used for data analysis. A P < 0.05 was considered significant. Results: Cough score (P = 0.458), post-intubation score (P = 1.000), and sedation score (P = 1.000) were comparable among the two groups. Hemodynamic responses and propofol and lignocaine requirements were also comparable. Conclusion: Both fentanyl and nalbuphine provide comparable intubating conditions when used before awake fiberoptic intubation with minimal adverse effects on hemodynamic profile.


Background: Leucocyte telomere length (LTL) is a biological marker of aging and reduced LTL is associated with adverse cardiovascular outcomes. Reduced regenerative capacity has been suggested as a...


The design, planning, performance and getting a harmonious smile brought an advance of Dental Materials, of clinical use and laboratory, and changes in esthetic restorative techniques. Diastemas are spaces between adjacent teeth which usually cause an esthetic discomfort of the patient. Ceramic veneers are a good alternative to offer the patient for a functional and harmonious smile with excellent optical properties. In addition to the biocompatibility with the tooth and gingival structure, color stability and durability of a long term, however, the execution of treatment with these material implications prior planning, aesthetic analysis of a through digital photography and smile Design, waxing diagnosis, Mock-up, Testing model, knowledge of material properties, domain the clinical preparation of tooth structure preserving healthy tissue through selective wear, in addition to the temporary restoration technique and protocol for cementation. This clinical report aims to present a technique of indirect restorative treatment with ceramic veneers for diastema closure in order to harmonize smile.