We introduce tf_geometric1, an efficient and friendly library for graph deep learning, which is compatible with both TensorFlow 1.x and 2.x. It provides kernel libraries for building Graph Neural Networks (GNNs) as well as implementations of popular GNNs. The kernel libraries consist of infrastructures for building efficient GNNs, including graph data structures, graph map-reduce framework, graph mini-batch strategy, etc. These infrastructures enable tf_geometric to support single-graph computation, multi-graph computation, graph mini-batch, distributed training, etc.; therefore, tf_geometric can be used for a variety of graph deep learning tasks, such as node classification, link prediction, and graph classification. Based on the kernel libraries, tf_geometric implements a variety of popular GNN models. To facilitate the implementation of GNNs, tf_geometric also provides some other libraries for dataset management, graph sampling, etc. Different from existing popular GNN libraries, tf_geometric provides not only Object-Oriented Programming (OOP) APIs, but also Functional APIs, which enable tf_geometric to handle advanced tasks such as graph meta-learning. The APIs are friendly and suitable for both beginners and experts.


The report aims is to clarify the concept of "green architecture" in the context of the new CAP in the period 2021-2027. The methods used are analysis of the literature and official regulations of the EU and the Member States. The result is an outline of the ideas of "green architecture". The conclusion is focused on the future effect of it for the Member States of the EU.


Detritivores of the fish family Curimatidae are assigned to eight genera, one of which, the Curimatopsis, with only five species, is the least speciose genus and sister to other seven genera in the family. Ongoing morphological investigations reveal, however, the likely existence of additional species. In this study, fifty‐one specimens of Curimatopsis from multiple rivers of the Amazon, Paraguay and Suriname drainages were identified morphologically according to the present species concepts and then barcoded using the universal cytochrome c oxidase subunit I (COI) mitochondrial marker. Species delimitation analyses were conducted using Bayesian methods through the general mixed Yule‐coalescent analysis combined with conventional likelihood, genetic distance and haplotypic diversity approaches. We found eleven well‐supported clusters that represent four of the named species and seven cryptic, undescribed species of Curimatopsis. Our results show a clear delimitation of species boundaries constrained by distinct Amazonian river ecotones that may have promoted intrageneric lineage diversification. This is the first of a series of genetic studies applicable to future taxonomic, phylogenetic and evolutionary studies across the Curimatidae.


In the Northwest Territories, there are daily demands for interpreting and translating in all the Dene languages. The people who perform this role rarely have the opportunity to specialize in any specific field, so they must try to develop an understanding of as many subjects as they can. This paper highlights some of the inter-lingual difficulties faced by the interpreters, along with a brief explanation of the methods used to develop new terminology in the Dene languages. It is demonstrated that the methods used in Dene language terminology development are the same as those used in other languages.


This study aims to analyze the influence of the current ratio, return on assets, and debt to equity ratio on Financial Distress condition of a company. This research used secondary data from annual reports on manufacturing firms listed in the Indonesia Stock Exchange (IDX) period 2009-2012. The samples of the study are 61 companies. The data analysis used in the study is logistic regression. The results of this study show that current ratio, return on assets, and debt to equity ratio can predict financial distress of the companies. The results also show that companies with high return on assets, have a little probability to get financial distress.

Keywords: Financial distress, Current Ratio, Return on Assets, Debt to Equity Ratio.


Professors Grieco and Ikenberry focus on the dynamic, reciprocal relationships between states and world markets, articulating the ways in which their interactions shape the world economy today. Intellectually challenging yet perfectly pitched to the undergraduate student, written by experts in the field, and combining the best of current political and economic theory, State Power and World Markets will enrich and further focus the undergraduate study of international relations.


This paper deals with the modeling and estimation of the sociological phenomena called segregation in social networks. Specifically, we present a novel community-based graph model that represent segregation as a Markov bridge process. A Markov bridge is a one-dimensional Markov random field that facilitates modeling the formation and disassociation of communities at deterministic times which is important in social networks with known timed events. Based on the proposed model, we provide Bayesian filtering algorithms for recursively estimating the level of segregation using noisy samples obtained from the graph. Numerical results indicate that the proposed filtering algorithm outperforms the conventional hidden Markov modeling in terms of the mean-squared error. The proposed filtering method is useful in computational social science where data-driven estimation of the level of segregation from noisy data is required.


Human workers and robots are two major workforces in modern factories. For safety reasons, they are separated, which limits the productive potentials of both parties. It is promising if we can combine human's flexibility and robot's productivity in manufacturing. This paper investigates the modeling and controller design method of workspace sharing human-robot assembly teams and adopts a two-layer interaction model between the human and the robot. In theoretical analysis, enforcing invariance in a safe set guarantees safety. In implementation, an integrated method concerning online learning of closed loop human behavior and receding horizon control in the safe set is proposed. Simulation results in a 2D setup confirm the safety and efficiency of the algorithm.


The hydroxamic acids (RC(O)NHOH, HA) exhibit diverse biological activity, including hypotensive properties associated with formation of nitroxyl (HNO) or nitric oxide (NO). Oxidation of two HAs, benzohydroxamic and acetohydroxamic acids (BHA, AHA) by [Fe(CN)5NH3]2− or [Fe(CN)6]3− was analyzed by spectroscopic, mass spectrometric techniques, and flow EPR measurements. Mixing BHA with both Fe(III) reactants at pH 11 allowed detecting the hydroxamate radical, (C6H5)C(O)NO˙−, as a one-electron oxidation product, as well as N2O as a final product. Successive UV–vis spectra of mixtures containing [Fe(CN)5NH3]2− (though not [Fe(CN)6]3−) at pH 11 and 7 revealed an intermediate acylnitroso-complex, [Fe(CN)5NOC(O)(C6H5)]3− (λmax, 465 nm, very stable at pH 7), formed through ligand interchange in the initially formed reduction product, [Fe(CN)5NH3]3−, and characterized by FTIR spectra through the stretching vibrations ν(CN), ν(CO), and ν(NO). Free acylnitroso derivatives, formed by alternative reaction paths of the hydroxamate radicals, hydrolyze forming RC(O)OH and HNO, postulated as precursor of N2O. Minor quantities of NO are formed only with an excess of oxidant. The intermediacy of HNO was confirmed through its identification as [Fe(CN)5(HNO)]3− (λmax, 445 nm) as a result of hydrolysis of [Fe(CN)5(NOC(O)(C6H5)]3− at pH 11. The results demonstrate that hydroxamic acids behave predominantly as HNO donors. Graphical abstract


Aiming at the problem of radiation sensitivity of double conductor transmission lines, this paper carries out simulation analysis from two aspects of certainty and uncertainty. In the deterministic case, the transmission lines with different load impedance at different angles are simulated and analyzed. In the case of uncertainty, Monte Carlo method is used to simulate the radiation sensitivity of double conductor transmission lines, and the effective mean and upper limit of radiation sensitivity response current are obtained.


On June 6, 1796, an entire community of black Jamaicans, numbering nearly 600, set sail reluctantly from Port Royal, en route to Halifax, where an uncertain future awaited them. The voyage was not of their own making. Victims of British deceit during the protracted conflict which has come to be known as the "Second Maroon War", these people had been thrust into the realization of their own worst fears. The Trelawny Maroons, as they were called, were the descendants of rebel slaves who had escaped into the interior, formed their own communities, and finally, completed peace treaties with the British colonial government in 1739. After rebelling again in 1795, the Trelawnys had eventually surrendered to the British, on the condition that they would not be removed from the island. The plantocratic government, however, had found it possible, once its mission was accomplished, to justify on technical grounds an egregious violation of the good faith on which the Maroons had surrendered. Putting the finishing touch to a military campaign distinguished by continual episodes of treachery, the British had decided to punish their van quished enemy by doing precisely what they had earlier promised not to do: deporting them en masse from the island. As is well known, the Trelawny Maroons were finally brought, as a result of this decision, to Nova Scotia, where they spent a few unhappy years. After numerous complaints, they were removed to what was to be their final destination, Sierra Leone, where their descendants live today.2 When the Trelawnys departed Jamaica in 1796 they left behind them a number of other Maroon communities with histories similar to


A Chinese language interpretation system is developed and presented in this paper. The system contains a knowledge-source module describing the various possible combinations of Chinese words, and an expert system for extracting the meaning of an input sentence. Application of the system in controlling a robotic arm is investigated and the results are satisfactory.


Abstract Objective  This study aimed to analyze the association between acute kidney injury (AKI) and abnormalities on brain magnetic resonance imaging (MRI) or death in neonates treated with therapeutic hypothermia for hypoxic-ischemic encephalopathy (HIE). Study Design  This is a retrospective case–control analysis of 380 neonates born at ≥35 weeks' gestation treated with therapeutic hypothermia for HIE. Death or abnormal brain MRI using the basal ganglia watershed scoring system was compared between neonates with and without AKI. Results  A total of 51 (13.4%) neonates had AKI. Infants with AKI had higher rates of the composite of death or abnormal brain MRI (74.5 vs. 38.3%; p  < 0.001). Rate of death (21.6 vs. 5.5%; p  < 0.001) and severe abnormalities on MRI or death (43.1 vs. 19.1%; p  < 0.001) were also higher in neonates with AKI. Conclusion  AKI is strongly associated with abnormalities on brain MRI or death in neonates with HIE. Identification of AKI in this patient population may be helpful in guiding clinical management and predicting potential neurodevelopmental impairment. Key Points Neonates with HIE are at increased risk for AKI. AKI is associated with hypoxic-ischemic injury on brain MRI or death among neonates with HIE. Identification of AKI in infants with HIE may help predict neurodevelopmental impairment.


The pollen grains of different plant taxa exhibit various shapes and sizes. This structural diversity has made the identification and classification of pollen grains an important tool in many fields. Despite the myriad of applications, the classification of pollen grains is still a tedious and time-consuming process that must be performed by highly skilled specialists. In this paper, we propose an automatic classification method to discriminate pollen grains coming from a variety of taxonomic types. First, we develop a new feature that captures the spikes of pollen to improve the classification accuracy. Second, we take advantage of the classification rules extracted from the existing pollen types and apply them to the new types. Third, we introduce a new selection criterion to obtain the most valuable training samples from the unlabeled data and therefore reduce the number of needed training samples. Our experiment demonstrates that the proposed method reduces the training effort of a human expert up to 80% compared to other classification methods while achieving 92% accuracy in pollen classification.


BeppoSAX has been added to the 3rd Interplanetary Network of gamma-ray burst detectors. Of the ≈8 events observed to date by Ulysses and the BeppoSAX Gamma-Ray Burst Monitor (GRBM), four have been localized by triangulation, resulting in annuli whose 3 σ widths are as small as 63″. These data give error boxes whose sizes can be as much as an order of magnitude smaller than those obtained with the SAX Wide Field Camera (WFC). They can be used to confirm the association between fading X-ray and optical sources and gamma-ray bursts.


profit levels, and does not face the stiff foreign competition confronting the textile industry. These differences and the contrasting responses of the two industries to health problems may generalize to other industries. The reasons for choosing the aerospace industry are less clear. The industry lacks either major health or safety problems. As the authors indicate, the accident rate in the industry is onethird to one-half the manufacturing average. Also, because of the government contracts the aerospace industry has received over the years, it was subject to safety regulation long before OSHA. An analysis of an industry with a more "average" safety record would have been preferable. This choice does not detract from the overall quality of the individual studies, though. The analysis of the VC problem and the response of OSHA, the chemical industry, and labor during the standard-setting process provide important insights into the promulgation of standards. The authors note that not only was the standard made with incomplete and conflicting scientific data concerning "safe" exposure levels, but the validity of the arguments and data introduced by the parties was colored by each party's interest in the rule-making process. The authors point out that the chemical industry's prediction of the economic effect of the one part per million (ppm) VC standard that was adopted was not accurate and may hurt the industry's credibility in future proceedings. These observations may also apply to other known or suspected occupational health hazards that may be subject to government regulation. The analysis of noise and byssinoisis (brown lung) hazards in the textile industry is notable in light of the events that have occurred since the publication of the book. The authors discuss the relative merits of engineering controls versus personal protective equipment as a means of dealing with both hazards. In the summer of 1978 after the book was published, engineering standards were chosen over personal protective quipment as a means of dealing with cotton dust. This decision was ultimately made by the President and clearly supports one of the book's contentions-that standard setting is primarily a political process. The principal theme is that the OSHA regulatory process is not sensitive to the costs and benefits of regulation in each industry. The authors state: The thrust of these observations i to argue for finer differentiation of hazards, industries and firms on the basis of problems perceived by employees and employers . . . Such differentiation on the formal level has, however, thus far been unacceptable in the regulatory process for political reasons which have encouraged less rather than more differentiation f problems-a phenomenon which is not uncommon with the substitution of a centralized (regulatory) for a decentralized (market) system of decision making for terms and conditions of employment (p. 542).


This study mainly uses asset/salary ratio model to assess the financial planning of Provident Fund Scheme in Macau based on assumptions of growth rate of salary, inflation rate, return on investment, tolerant risk, exchange rate risk, length of working, and length of retirement life under the current economic perspectives. The main findings show that the age of 36 can attain the income replacement ratio at 30%; the age of 44 at 50%; the age of 54 at 70% given the first year of working is age of 25. In addition, this study also proposes that the Fundo de Pensões de Macau should select the types of global stocks mutual funds prudentially and also should educate the public servants to use asset/salary ratio as a measure to assess whether it can achieve the target income replacement ratio and to balance the portfolio.


Relative toxicity of insecticides viz., clothianidin, bifenthrin, imidacloprid, spinosad, thiacloprid, flubendiamide, flonicamid and dimethoate is reported against cowpea aphid, Aphis craccivora Koch. Clothianidin @100 g a.i ha−1 was the most effective in bringing down the population of aphid at 1, 3, 7 DAS, while at 10 DAS, dimethoate (450 g a.i. ha−1) recorded the lowest incidence of aphid population (4.49 number per plant) with highest per cent reduction (79.19). The highest mean yield of 13.08 q ha−1 was obtained from dimethoate 450 g a.i. ha−1 followed by imidacloprid 20 g a.i. ha−1 (12.25 q ha−1) as compared to the lowest in the untreated plots (9.17 q ha−1). The highest benefit was achieved in the plots treated with imidacloprid 20 g a.i. ha−1 with a benefit-cost ratio of 8.72: 1 whereas the lowest benefit cost ratio of 0.37: 1 was obtained from the plots treated with spinosad 45 g a.i. ha−1. In laboratory, following dry film bioassay, the LC50 (at 24 h) of clothianidin, bifenthrin, imidacloprid, spinosad, thiacloprid, flubendiamide, flonicamid and dimethaote were found to be 0.031, 0.117, 0.063, 0.912, 0.042, 0.027, 0.079 and 0.057 ppm with the order of toxicity flubendiamide> clothianidin > thiacloprid > dimethoate >imidacloprid >flonicamid> bifenthrin >spinosad, respectively. Taking dimethoate as unity, the order of relative toxicity of insecticides was: flubendiamide (2.11)> clothianidin (1.83)> thiacloprid (1.35) > imidacloprid (0.90)>flonicamid (0.72)> bifenthrin (0.48)>spinosad (0.06) at 24 h. It was concluded that though dimethoate 450 g ai. ha−1 was an equally effective insecticide against A. craccivora as imidacloprid, the latter was more effective in terms of aphid population reduction, yield and benefit-cost ratio. Considering the LC 50 values and relative toxicity against A. craccivora, flubendiamide 60 a.i ha−1 was the most toxic and spinosad 45 a.i ha−1 the least toxic among the tested chemicals.


There is a paucity of medical literature regarding the efficacy of lock solutions in preventing catheter thrombosis. Traditionally, heparin has been used as the anticoagulant of choice for catheter locking, but it has many adverse effects associated with its use. Sodium citrate 4% is an attractive alternative to heparin.


This interpretive grounded theory (GT) study describes and analyzes emotions in leadership in a Nordic inter-organizational information system (IOIS) project which spanned four user organizations, two suppliers, one national organization, a research organization and a Ministry. This study shows how GT can be used to gain significant insights into a case study, and generate new concepts. We identified Certainty, Significance, Connection and Contribution as important selective codes that make up the Emotions category. The paper focuses on leadership issues in the emotion category. The paper concludes by discussing how some of leadership issues could be attributed to emotions issues and considers some theoretical and practical implications.


In this research the relationship between hair cortisol and burnout was evaluated through the study of third-variables effect. Hair cortisol concentration was measured in 234 health workers. All participants completed perceived stress survey and Maslach Burnout Inventory. Our results showed that 40% of volunteers presented altered hair cortisol values, 12% burnout, 33% showed high depersonalization, 38% high emotional fatigue, 36% low personal fulfillment and 22% presented 2 of the 3 burnout components. A moderated mediation was found between psychological and biological variables. This research highlights the importance of including a biological variable such as hair cortisol in burnout assessment.


: Now-a-days Power consumption (or) power dissipation has becomes the most important criteria for implementing anyone of the circuit. While calculating the efficient value of the output of that particular circuit, we may use the concept of scaling. But, while increasing the scaling process there may be a loss of leakage current. Due to the leakage current the usage of power (power dissipation) is increased. For removing these kinds of leakage currents we are going to use "power gating techniques". By using the power gating technique we can provide better power efficiency also. In this paper we are going to analyze the circuits using "MTCMOS" of power gated circuits with the help of low power VLSI design technique compare with other power gating techniques. The entire procedure may implement and simulated using Micro-wind Layout Editor & D. Sch (Digital Schematic).


N THE FIRST PART OF THE STUDY, we review and discuss the recent evolution of the literature on border effects in light of Anderson and van Wincoop's (2001) proposed solution to the border puzzle. We argue that these authors have taken a critical step forward regarding the information contained in border effect estimates. In the second part of the study, we estimate border effects for Canada and the ten provinces with a sample spanning the years 1981-2001. For most provinces and for Canada as a whole, the border effect on goods trade appears to have been declining steadily over the 1981-2000 period.


Curdlan and its branched derivatives having oligo-L- or oligo-D-arabinofuranose side chains, D-glucopyranose side chains or D-galactopyranose side chains were sulfated with piperidine N-sulfonic acid or SO3-dimethylform-amide complex. The structures of the sulfated polysaccharides were analyzed by elemental analysis and 13C NMR spectroscopy. The 13C NMR spectra of curdlan sulfates were assigned and the degree of substitution (DS) value of each hydroxyl group was obtained. The reactivity was in the order C-6 C-4 = C-2. However, a little different distribution of substituents was observed between curdlan sulfates synthesized with piperidine N-sulfonic acid and SO3-DMF complex. Sulfated polysaccharides with high d.s. values showed high anti-HIV (AIDS virus) activity.


This article presents the development and validation of a hybrid multi-sphere discrete element framework - Rigid3D, for the simulation of granular systems with arbitrarily shaped particles in 3D space. In this DEM framework, a non-spherical particle is approximated by three different geometric models: (1) multi-sphere model with overlapping spheres (MS model), (2) particle surface with triangle mesh (surface model), and (3) discretized particle body with polyhedral cells (cell model). The multi-sphere approach will be the"engine"for efficient DEM simulations, while the particle's mesh and cell models will be updated simultaneously according to the position and orientation of their associated MS model, for use in particle-related inter-phase couplings in a multi-phase flow. In this sense, Rigid3D tries to combine the best of both worlds in multi-sphere and polyhedral DEMs: multi-sphere method for the efficiency and acceptable accuracy in the DEM simulation of granular flows, while the surface and cell models for the couplings between particles and other phases (continuous or dispersed phases) without affecting the performance of DEM simulations.


The efficiency of the Air Conditioning (AC) system in a car depends on the process of compression, condensation, and evaporation. The new thought that arises is what if the diameter of the condenser fan blade is varied? The objectives of this study are: (1) to test the effect of the diameter of the condenser fan blade on AC temperature, and (2) to test the effect of condenser fan rotation speed on AC temperature. This research is using an experimental method. The results showed: 1) there was an effect of the diameter of the condenser fan on AC temperature, which was 16.7%; and 2) there is an influence of condenser fan rotation speed on AC temperature that is equal to 20.5%. These findings become a reference that to improve the performance of the AC, it can be done by increasing the heat transfer process in the condenser.


Bridges to Humanity: Narratives on Anthropology and Friendship. BRUCE GRINDAL and FRANK SALAMONE. Prospect Heights, IL: Waveland Press, 1995. 260 pp., references.


The traditional teaching model of national vocal music in colleges and universities has some problems, such as low quality of teaching, poor diversity of teaching, and low interest of students. Based on this, this study studies the innovation of the teaching model of national vocal music in colleges and universities based on the deep recurrent neural network algorithm and designs the teaching quality evaluation model based on the deep recurrent neural network algorithm. The collection of data and information is realized from the aspects of students' class state, vocal music examination results, classroom interaction, etc., and the comprehensive analysis is carried out using the deep recursive neural network algorithm, to realize the multiple analysis and objective evaluation of the whole process of different teaching modes of national vocal music in music colleges and universities, according to the different characteristics and teaching objectives of the teaching process of national vocal music in music colleges and universities The standard requires accurate analysis and evaluation. The results show that the optimization model based on the deep recurrent neural network algorithm has the advantages of high feasibility, high intelligence, and wide range of applications. The experiments show that the deep recurrent neural network algorithm can analyze the effectiveness of the innovation model, and the fuzzy evaluation method can realize the comprehensive evaluation of the innovation mode, which is conducive to the improvement of students' vocal music learning ability.


Benefiting from the unique chain walking characteristic of late transition metal complexes, branched EPR-like elastomers bearing distinct differences compared to traditional linear EPRs are reported herein. Firstly, a series of...


With the economic rapid development and the natural resource shortages, the state promote marine development strategy which make the management and utilization of uninhabited island becomes more and more important. Depending on the characteristics of uninhabited island's development and management, this article provides ideas and solutions for management to develop policies or take measures by researched and analyzed the related problems.


Eggs and nymphs of Cicadulina chinai Ghauri are generally larger in length and in certain other measurements than those of Cacadulina bipunctella zeae China, at comparable stages of development. Apart from these differences in measurements, comparative description of eggs at various stages of embryonic development, and of nymphs at various instars, revealed some differences that might be used for differentiation of the two species at the immature stages. Colour of mycetome in the eggs, and colour and relative size of the two brown blotches on the dorsum of the last abdominal segment in second to fifth nymphal instars, were the most diagnostic features to separate the two species.


An epoxy resin system is a composition of multi-component copolymerized nylon toughened epoxy resin, derivatives of dicyanodiamide-dimethyl substituted urea, and a curing-catalytic composite curing system. The epoxy resin system has comparable long storage, keeping and using periods, and can be heated to a medium temperature (120 DEG C) for curing; the cured resin has excellent physical mechanical properties, and especially excellent dynamic mechanical properties. The epoxy resin system is recommended to be used alone as a metal structure adhesive, or to be used as pre-dip resin of resin-based composite materials, especially to be used for pre-dipping high-performance fibers or fabrics thereof to form high-performance composite material matrix resin adapted to the high-performance fibers after curing formation.


Background:
 In United States (US) emergency departments (ED), ~80% of patients presenting with exacerbation of heart failure (HF) symptoms are admitted to the hospital. However, some patients are at low-risk of adverse outcomes and might be effectively managed as outpatients. While ED HF risk prediction tools guide admission or discharge decisions, they have not been compared, are not routinely used in EDs, and do not include patient-reported outcomes that may be associated with prognosis.

 Objective:
 To assess the feasibility of collecting variables for three published ED-based HF risk prediction tools (table) and the capacity to collect participant-reported outcomes.

 Methods:
 We screened a convenience sample of patients age ≥20 years with symptoms of HF (e.g. shortness of breath, edema) receiving care in a US ED. We collected information from medical records, and administered a questionnaire to collect patient-reported outcomes and a 3-minute walking test. We developed a safety protocol to identify participants ineligible for the walking test.

 Results:
 We screened 66 patients and consented 31 (47%) participants. The average age was 61 years, 6 (19.4%) were female and 28 (90.3%) were admitted. We completed all the questionnaires with an average time of 31 minutes. For the walking test, 15 were ineligible per the safety protocol, 6 completed the test, and 10 did not consent. For the three HF tools, we collected an average of 93.4% of the variables needed per participant (range across tools 91.4%-97.7%; Table). The main missing variables were BMI on ED arrival (n=23) and troponin (due to hemolyzed values, n=5).

 Conclusion:
 We obtained complete data for the participant questionnaires, yet there were missing values for variables needed for the HF tools. The Emergency Heart Failure Mortality

 Risk Grade tool had the most complete data. If a research or clinical study plans to use these tools, the study protocol should include BMI and troponin measurements and consider alternative strategies to collect data, such as by self-report.


MICA and MICB (MICA/B) are expressed by many human cancers due to cellular stress and tag cells for elimination by cytotoxic lymphocytes through NKG2D receptor activation. However, tumors evade this immune recognition pathway through proteolytic shedding of MICA/B proteins. We rationally designed antibodies targeting the MICA α3 domain, the site of proteolytic shedding, and found that these antibodies prevented loss of cell surface MICA/B by human cancer cells. These antibodies inhibited tumor growth in multiple fully immunocompetent mouse models and also reduced human melanoma metastases in a humanized mouse model. Anti-tumor immunity was mediated mainly by NK cells through activation of NKG2D and CD16 Fc receptors. This novel approach prevents the loss of important immunostimulatory ligands by human cancers and reactivates antitumor immunity.

 Wucherpfennig: BMS: Research Funding; Novartis: Research Funding; TCR2: Consultancy; Tscan: Consultancy.


We thank Razaq et al. for their comments regarding our article titled "Sarcopenia in Children With EndStage Liver Disease on the Transplant Waiting List." We also appreciate their comments regarding the application of the term sarcopenia to children. Sarcopenia is a term derived from the Greek sarco (flesh) and penia (deficiency), without reference to age. Although multiple definitions of sarcopenia for adult and pediatric patients exist in the published literature, there is a general consensus that low muscle mass (however measured) is a powerful negative predictor of clinically relevant adverse outcomes.(1) Singleslice computed tomography (CT) of the abdominal psoas muscle area constitutes the beststudied technique for measuring sarcopenia in multiple studies of adults with cirrhosis, as it is not affected by ascites.(1) Studies to date using ultrasound measurements of thigh muscle thickness in adults with endstage liver disease (ESLD) show promise, being easy to perform and inexpensive, and avoiding radiation exposure; however, their use in pediatric populations with ESLD has not been explored. Current limitations include unknown reproducibility and decreased accuracy compared with crosssectional imaging.(2) We agree that targeting noninvasive assessment strategies for evaluating skeletal muscle mass in both adults and children with chronic diseases is a highneeds research area. Sarcopenia is part of a larger construct of global physical dysfunction that is prevalent in patients with ESLD. We absolutely agree that muscle function is an important component in muscle and nutritional assessments. We acknowledged the absence of functional measures as a limitation in our study. Sarcopenia is likely the biological correlate of "frailty," with loss of muscle mass suggestive that frailty may be present. Our group has established the feasibility of adapted frailty testing (which retains grip strength) in children older than the age of 5 years and chronic liver disease.(3) However, it is difficult, if not impossible, to assess muscle function or frailty in infants and young children, so additional strategies are needed. The North American Working Group on Sarcopenia recommends the assessment of sarcopenia using muscle mass only.(1) Indeed, among adult studies to date using singleslice CT in patients with cirrhosis, only a minority includes functional evaluations, with a recent systematic review revealing muscle assessments in only 2 of 38 studies.(4) We are excited that agematched and sexmatched reference values for the psoas muscle are now available in children, with an online calculator available also available,(5) setting the stage for future research to achieve consensus and standardized tools for this population.


Current debate focuses on the consequences of massive layoffs and the search for ever-increased productivity. In this perspective, the future of work points towards even greater unemployment. This article proposes a different interpretation: the major trend is not so much towards the 'end of work' but to strategic expansion, through economic concentration and the externalization of labour. Evidence is given to demonstrate this thesis, with empirical examples in different industries at national and international level. The externalization process which characterizes current economic restructuring is directly related to the search for greater flexibility. As a result of fierce competition, different forms of labour organization are appearing as well as new costs for society. This article concludes that today's 'cascading subcontracting' is not only related to the externalization of labour costs, but also to the externalization of risks and responsibilities and, as such, contradicts more and more the basic principles of democracy.


Abstract. We hypothesized that in healthy subjects differences in resting heart rate variability (rHRV) would be associated with differences in emotional reactivity within the medial visceromotor network (MVN). We also probed whether this MVN-rHRV relationship was diminished in depression. Eleven healthy adults and nine depressed subjects performed the emotional counting stroop task in alternating blocks of emotion and neutral words during functional magnetic resonance imaging (fMRI). The correlation between rHRV outside the scanner and BOLD signal reactivity (absolute value of change between adjacent blocks in the BOLD signal) was examined in specific MVN regions. Significant negative correlations were observed between rHRV and average BOLD shift magnitude (BSM) in several MVN regions in healthy subjects but not depressed subjects. This preliminary report provides novel evidence relating emotional reactivity in MVN regions to rHRV. It also provides preliminary suggestive evidence that depression may invo...


Background: Intestinal obstruction in the neonate is a common indication for neonatal emergency surgery. Failure to pass meconium by a full-term neonate within the first 24 hours of life should raise a suspicion of bowel obstruction. The objective of this study was to determine pattern of presentation, diagnosis and outcome of management of intestinal obstruction in the neonates at the Abia State University Teaching Hospital Aba. Methodology: A Prospective study of fifty-four neonates who presented with clinical and radiological findings consistent with intestinal obstruction that was treated at Paediatric Surgical unit, Department of Surgery, of the Abia State University Teaching Hospital Aba between October 2016 to 0ctober 2018. Proforma was opened for sex, weight, age at presentation, clinical presentation, duration of symptoms prior to presentation, surgical pathology, treatment offered, complications and management outcome Results: During the twenty-five months period, Eight hundred babies were admitted at the special care baby unit of the hospital. Fifty-four babies (6.75%) of these were cases of neonatal intestinal obstruction. There were 40 males and 14 females, with male to female ratio of 4:1. The mean weight of the neonates was 2.5kg (range 1.1-4.3kg). The average age at operation was 3 days (1-15days), the mean duration of symptoms before presentation was 3.5days. The major indication for operation was Anorectal malformation 32 patients {59.3%}, Hirschsprung's disease10 {18.5%}, Intestinal atresia 8 patients {14.8%}, obstructed hernia 4 patients {7.4%}. Conclusion: The morbidity and mortality of neonatal intestinal obstruction in this hospital is due to the problems of late presentation and poor neonatal intensive care facilities. The findings are at variance with those in developed countries.


In the ever-expanding realm of how-to books on writing for scholarly publishing, few avenues seem to remain unexplored. Imagine my delight, then, upon learning of this pioneering volume by Leo Mallette (an adjunct at Pepperdine University) and doctoral student Clare Berger (also at Pepperdine). Having a background in the humanities and social sciences, I presumed that the book would explore the connection between conference presentations and subsequent publications in scholarly outlets: In many humanities and social science fields, for example, the papers presented at academic conferences are often early drafts of articles-inthe-making. Feedback garnered at conferences is — at least in theory — incorporated into revisions, thus strengthening the resultant journal submissions. But beyond repeatedly making the point that 'many peerreviewed journal articles start out as an idea that was presented at a conference' (54), this book does not traverse the ground I was expecting. Instead, the book is principally about writing for publication at conferences, namely, through the vehicle of conference proceedings. Therein lies the main oversight of the authors: Readers — particularly members of the target audience of 'graduate students and young professionals' (vii) who are still being socialized into professional norms and expectations — might not yet understand the roles of conferences and conference proceedings within their fields. More consequentially, readers might not understand the potential ramifications of such publishing activity on their future careers. In the humanities, for example, Wendy


Regional and in-country information networks aid national governments in effecting policy and developing maternal and child health/family planning (MCH/FP) programs cohesively. A host country or institution that used regional and local policy and program development agencies (i.e. a network approach) strengthens the prospect of specifically developing similar objectives and priorities. The Center for Applied Research on Population and Development (CERPOD) in Bamako Mali facilities the strengthening of family programs in the Sahel by improving management information systems program evaluation and applied research. CERPOD can incorporate regional activities in countries that have like needs for policy research and MCH/FP program development. For example it has set up a network of researchers in MCH/FP programs. The Population Council and CERPOD have joined to improve operations research (OR) capabilities and to develop OR projects. In addition in April 1989 a reproductive health network for certain nations of Africa coordinates national research units created by the Population Council. The network serves as a means for the exchange of experiences and an impetus for locating national resources for reproductive health research. An OR/TA project in Zaire has a management consultant in a government family planning project which has established an informal network within Zaire. The advisor coordinates efforts between local institutions among donors and between donors and the host government. Networks can combine various funding sources and human resources and develop an institutional means to exchange funding sources and human resources which leads to effective development of MCH/FP policies and programs in Africa.


Objective To investigate the cardiac structure and the function by echocardiography and their correlation with liver functon in cirrhotic patients.Methods A total of 35 cirrhotic patients and 20 healthy controls were enrolled in the study.Thirty-five cirrhotic patients were divided into group A,group B and group C(Child A group,Child B group and Child C group) according to the Child-Pugh score.Dimensional Doppler echocardiography was investigated and cardiac dimensions and left and right ventricular functions were evaluated.Results In liver cirrhosis group,LAs, IVS and AAO increased as compared with those of healthy group,whereas the value of E/A was reduced(P0.05, respectively).There was no significant difference between the Child A,B and C group for IVS,AAO and the value of E/ A.Data of LAs in each group was compared,showing that Child AChild C and Child B Child C(P0.05, respectively).Conclusion The cardiac systolic and diastolic function of patients with cirrhosis are deficient,and the degree of cardiac insufficiency is related to the damage of liver function.Our research confirmed the existence of cirrhotic cardiomyopathy.The possibility of cirrhotic cardiomyopathy should be considered if LAs increases and the E/A 1.


One unit of P3B Jawa Bali, Central Java and DI Yogyakarta region responsible for operating and maintaining the installation of electric power transmission network in Central Java and Yogyakarta. With the transmission network configuration changes for reasons of consumer needs and for the reliability of the power supply necessary to study the effect of changing the configuration of the coordinated protection system conductor. As happened in the subsystem Kudus-Jekulo-Pati is changing the configuration of the GI Jekulo single phi into a double phi. This change affects the coordination of in the subistem, which overlap in Zone 2 distance in the direction of the GI Kudus-Jekulo to Zone 2 distance relays in GI Jekulo Pati direction, it is known after the scanning process. And to anticipate the problems it is necessary to resetting or setting recalculation distance relay is in the GI Kudus-Jekulo direction, which is expected to resetting, the coordination of protection systems in the susbsistem Kudus-Jekulo-Pati as expected. With better coordination of the protection system conductor protection relay performance became more selective and sustainable electricity distribution maintained the need for electricity can be met in an optimal, effective and efficient. protection systems Keywords : electric power transmission, protection systems,Distance relay, scanning coordination of protection systems


: The NSW Department of Planning and Environment (NSW DPE) has been developing regional water strategies (RWS) to enhance the management of water for improved water security. The strategies develop a long list of water management options through community consultation that aim to determine future water demand, and to identify challenges, choices, and solutions in meeting those demands. The likely hydrological, economic and ecological effects of those options more focused on providing water security during drought is then assessed. This modelling approach is also described by Dutta et al. (2023) for the Murray and Murrumbidgee Rivers. RWS modelling includes the development of base case models, which can then be compared to options models, to inform hydrological, cost-benefit and ecological analysis. All these options are assessed using different long-term hydrological time series: (1) current river operational models (Instrumental), (2) modelled past climate data (Stochastic) and (3) drought impacts under more extreme climate change scenarios (NSW and ACT Regional Climate Modelling, or NARCliM). The South Coast RWS work includes an additional east coast low model (ECL). This paper is focused on the ecological and coastal components of RWS ecohydrology work (NSW DPE 2022 a-c), with the Bega River as an example. The Bega River is within the South Coast region, which is a highly significant and diverse ecological area. The reach of the Bega River between Bega township and the Bega River estuary supports a small floodplain that includes paleochannels and wetlands, and areas that have been modified for irrigation. The lower Bega River estuary is in a relatively natural state, with extensive forest cover on the slopes of the immediate catchment, and areas of wetland (including lagoons) and saltmarsh. The ecohydrology impacts of three water management options as compared to current conditions (base case) were assessed at representative locations along the river under Stochastic, NARCliM and ECL conditions. These were: Option 1. Increased on-farm water storage with low-flow bypasses and active water markets that increase opportunities for irrigators to access water that is not being used through trade. Option 2. As per Option 1, but also including a pumped hydro scheme and Option 3, which is as per Option 2, but with a larger on-farm water storage. Although the ecohydrology metrics used were generic measures, rather than catchment-specific measures the predicted ecohydrology impacts predicted were consistent with what is known of the Bega River and flow effects usually associated with increased flow regulation and abstraction. These methods were fit-for-purpose to aid an option prioritisation process but could need refining for different water management questions.


The effects of PbII on the secondary structure and biological activity of trypsin have been examined by monitoring changes in its conductivity and IR and circular dichroism (CD) spectra. The results show that PbII reacts with trypsin, and that the binding sites might be OH and NH groups in pepsin. The CD spectra indicate that interaction with PbII significantly affects the secondary structure of trypsin, the β‐sheet‐structure content being increased by about 42 %, whilst those of α‐helix and β‐turn structures are decreased by 13 % and 21 %, respectively. The results clearly demonstrate that PbII affects the biological activity of trypsin by modifying its secondary structure. Most interesting is that PbII up‐regulates the activity of trypsin at low concentrations while down‐regulating it at high concentrations.


In the sphere of image processing, image data investigation is required related to a specific application in order to extract the suggestive information and reach defined and crisp culminations. One of the most significant phase in image processing is feature extraction which is the third step following image acquisition and segmentation. The procedure of reconstructing the input image into a group of features is named as feature extraction. These features construe the textural characteristics of the image. Texture feature extraction is one such significant part of feature extraction that on majority influences the results of classification. A texture is principally based on recognizing the object or region of interest in an image. The Local Binary Pattern feature descriptor will be the pith of discussion of this paper. LBP is a texture operator that operates on an image by labeling its pixels by thresholding neighborhood of each pixel. Various quality journals have been referred in order to provide an insight into the trends in pattern recognition using LBP.


The reaction of an excess of dry hydrogen chloride with a benzene solution of [RhCO(Ph{sub 2}PCH{sub 2}CH{sub 2}CN){sub 2}Cl] results in the quantitative formation of [RhCO(Ph{sub 2}PCH{sub 2}CH{sub 2}CN){sub 2}Cl{sub 3}]. In a water-benzene mixture the nitrile group is coordinated diphenyl(2-cyanoethyl)phosphine undergoes hydrolysis with the formation of products, whose character depends on whether HCl is present in the solution.


A new method of improved viewing angle of STN-LCDs was studied. Adopted method of multi-domain compensating for viewing angle of TN-LCD. In this paper, we reported the double domain STN LCD cells' structure and fabrication process, applied twice rubbing technique and lithography process and accurately orientation. We compared with the viewing angle characteristics of the conventional STN and the DDSTN. Compare with them, you will find that viewing angle of the DDSTN is more improved, it changes wide and uniform, and it is wider than viewing angle of the conventional STN. We also compared the conventional STN with the DDSTN on electric-optics characteristic each other. We analyzed the reason of contrast decrease of the DDSTN LCD, discussed the solvable method.


Increased enrolment of international nursing students in undergraduate and postgraduate programs is predicted as Australian universities compete for students in the globalised university market. This study explored issues impacting on the ability of international nursing students to achieve their study goals at an Australian university (n=29). However, this paper principally describes the design of the instrument by two nursing lecturers and international nursing students (n=10) in a collaborative process, characterised by a pluralistic world view and the enactment of virtue ethics. The myth of the term 'ESL' is critiqued, and challenged. In designing the instrument, we argued it was essential to be cognisant of the conceptual attributes and embedded meanings of language for the unique study population, to ensure face and content validity. D esign of the data collection instrument is usually described in one to two paragraphs of a research paper. However we believe the methodological issues specific to the process of the design of the instrument in a study entitled, 'On-campus International Nursing Students: experiences and reflections', warranted discussion in this discrete paper. The study built on previous research (Cecchin 1998) that examined the experiences of providers of education programs for international nursing students, revealing the need for nurse educators to have a greater understanding of the learning needs of nursing students from diverse cultural backgrounds. Given these findings, it was essential to also explore students' perspectives. Using a questionnaire, this study explored the experiences of nursing students n=29 who left their homeland, family, employment and support networks to study in another country. It examined issues impacting on their ability to achieve their study goals and identified improvements in the learning environment for international nursing students. The study is to be reported in full elsewhere. In this paper, we describe the design of the data collection instrument used in the study. A key feature of the study was the collaboration between us, as the researchers, and the cohort of 1998 undergraduate and postgraduate international nursing students (n=10), in the design of the questionnaire.


Electronic program guide producing apparatus (1) includes a program information collection storage unit for collecting and storing program information from the desired information extracted from the digital broadcast signal (103), an electronic program guide producing apparatus (1) is placed time information providing unit for providing a first time information is the current time in the region in which the (105), the time information set in the digital broadcast signal is acquired as the second time information, first time information When a broadcasting station time difference information calculation storage unit the time difference to calculate the associates and stores the broadcast station specifying information between the second time information (104), the time included in the program information this time difference based on by correcting the a, program information correction unit for generating a time-corrected program information (106), an electronic program table generating unit for generating image data of an electronic program guide based on the time corrected program information and (107).


The chaos phenomenon among energy time series is discussed in this paper The series of energy production and energy consumption were reconstructed in phase space and the attractor dimension was computed by correlation dimension The result is that the correlation dimension between annual production and consumption of China energy is a positive fraction,the energy production time series sum embedding dimension m ∞ is 10,the corrlation dimension is 1 13(between 1 and 2) and the influential factors are between 2 and 10 The results computed by Kolmogorov Sinai entropy K 2 proved that the energy production time prediction time is in 9 years and the energy consumption is in 10 years


Hijamah is an Unani regimenal mode of treatment which is carried out by application of cup shaped glass or plastic vessels on the body surface, creating vacuum by heat or by special suction apparatus. Hijamah or cupping therapy is an important emerging alternative non-pharmacological regimenal mode of treatment. Hijamah is beneficial in a large number of disorders


Abstract Strategy use in single-digit addition is an indicator of young children's numeracy comprehension. We investigated Danish primary students' use of strategies in single-digit addition with interview-based assessment of how they solved 36 specific single-digit addition problems, categorised as either 'error', 'counting', 'direct retrieval' or 'derived facts'. The proportional use of each strategy was analysed as multi-level functions of school age and sex. In a first study (260 interviews, 147 students) we found decreasing use of counting and increasing use of direct retrieval and derived facts through years 1–4, girls using counting substantially more and the other two strategies substantially less than boys, equal to more than 2 years' development. Similar results appeared in a subsequent study (155 interviews, 83 students), suggesting that the pattern is pervasive in Danish primary schools. Finally, we ask whether sex differences in strategy use is generally under-reported since many studies do not explicitly address them.


A self -consistent, non -perturbative approximation scheme is proposed which i s potentially applicable to arbitrary interacting quantum systems. For the case of self interaction, the scheme consists in approximating the original interaction H I ( f ) by a suitable ' potential ' V( f ) which satisfies the following two basic requirements, ( i ) exact solvability (ES): the ' effective ' Hamiltonian, H 0 generated by V( f ) is exactly solvable i.e., the spectrum of states | n > and the eigen -values E n are known and (ii) equality of quantum averages (EQA): < n | H I ( f ) | n > = < n | V( f ) | n > for arbitrary ' n ' . The leading order (LO) results for | n > and E n are thus readily obtained and are found to be accurate to within a few percent of the ' exact ' results. These LO -results are systematically improvable by the construction of an improved perturb ation theory (IPT) with the choice of H 0 as the unperturbed Hamiltonian and the modified interaction, l H ¢ ( f ) " l ( H I ( f ) - V( f ) ), as the perturbation where l is the coupling strength. The condition of convergence of the IPT for arbitrary l is satisf ied due to the EQA requirement which ensures that < n | l H ¢ ( f ) | n > = 0 for arbitrary ' l ' and ' n ' . This is in contrast to the divergence (which occurs even for infinitesimal l !) in the na ï ve perturbation theory where the original interaction l H I ( f ) is chosen as the perturbation. We apply the method to the different cases of the anharmonic - and double well potentials, e.g. quartic -, sextic - and octic - anharmonic oscillators and quartic -, sextic double well oscillators. Uniformly accurate results for the energy levels over the full allowed range of ' l ' and ' n ' are obtained. The results compare well with the exact results predicted by super symmetry for the case of the sextic anharmonic - and the double well partner potentials. Further improvement in the accuracy of the results by the use of IPT, is demonstrated. We also discuss the vacuum structure and stability of the resulting theory in the above approximation scheme.


Various embodiments disclosed relate to an abrasive article. The abrasive article includes a nonwoven web. The nonwoven web includes a first irregular major surface and an opposite second irregular major surface. The nonwoven web further includes a fiber component comprising staple fibers having a linear density ranging from about 50 denier to about 2000 denier and a crimp index value ranging from about 15% to about 60%. The nonwoven web further includes a binder dispensed on the fiber component and abrasive particles dispersed throughout the nonwoven web.


From 2011 to 2014, the BESIII experiment collected about 5 fb−1 data at center-of-mass energies around 4 GeV for the studies of the charmonium-like and higher excited charmonium states. By analyzing the di-muon process e+e− → γISR/FSRμ+μ−, the center-of-mass energies of the data samples are measured with a precision of 0.8 MeV. The center-of-mass energy is found to be stable for most of the time during data taking.


The effect of ozoniferous air flux,pH,as well as initial concentration and quantity of activated carbon for degradation of a simulated dye wastewater of methylene blue was studied. Experimental results indicated that methylene blue wastewater was effectively decomposed using a low initial concentration of methylene blue and a high pH. For 90 min at an initial concentration of 100 mg·L-1 of methylene and pH of 9.5 with 9 g·L-1 of activated carbon,the removal rate for color was 95.6% and for the chemical oxygen demand (COD) was 64.8%. Activated carbon not only accelerated the generation of ·OH radicals,but also enhanced their reaction with methylene blue so that in the process of catalytic ozonation with activated carbon,indirect oxidation dominated. Compared with a single ozonation,the removal rate of COD was heightened.[Ch,7 fig. 13 ref.]


Lightning discharges are known to inject whistler waves into the inner magnetosphere over a wide region around their source. When a discharge occurs, it radiates electromagnetic energy into the Earth‐ionosphere waveguide, some of which couples into the whistler mode and propagates through the ionospheric plasma away from the Earth. Previous studies have discussed the effects of whistler‐induced electron precipitation and radiation belt losses associated with lightning. However, to date, there has been no research on the long‐term effects of this accumulated impact. Here, we use data from the World Wide Lightning Location Network, which has continuously monitored global lightning activity since 2004, to obtain 1 year of lightning data and categorized them into L‐shell ranges, hemispheres, and magnetic local times. We then use Van Allen Probe's Energetic Particle, Composition, and Thermal Plasma Suite from both satellites (RBSP‐A/B) to measure particle fluxes in the inner belts under the same criteria. We compare these two quantities by calculating the correlation coefficients between selected electron energy channels, including pitch angle distribution, and lightning activity under different conditions. Although we found a weak to moderate relationship between lightning activity and electron flux perturbations, the correlation was not as strong as expected from theoretical predictions. Variations in electron fluxes related to substorm activity were of the same order of magnitude as that from lightning activity, even at low L shells.


Data integration systems have been used for providing to the users information regardless of distribution and storage format, and their presence have became crucial on Information Technology. On a Ubiquitous Computing scenario, applications manipulate new types of data, with contextual and dynamic behavior, what makes integration process more difficult and complex. This work proposes a conceptual architecture for data access and integration for mobile and context-aware systems. A scenario on Tele medicine shows the advantages and functionalities of proposed architecture.


Let Y1ZM denote the class of functions analytic and univalent in the unit disc A subject to the conditions f(O) = 0, f(zo) = Zo, If(z) I <M, where zo, zo#0, is a fixed point of A and 1 <M? oo. In the present note, we determine by the method of circular symmetrization, the exact value of the "Koebe constant" for the class Y1M. We also determine Koebe sets for the class iM: consisting of the starlike functions, and for MIZ, consisting of all functions mapping A onto domains convex in the direction eia. By "Koebe set" we understand the set 3C((YrM), 3C(iMM) -nfwf (A)


Objective: The present review work is designed to gather knowledge about polycystic ovarian syndrome (PCOS) to manage and treat this endocrine disorder through three different perspectives viz, Allopathic, Unani and Ayurvedic studies from the absolute beginning of its onset among women of reproductive age group. Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders, affecting 2.2 to 22.5% of women in the reproductive age. As time elapses prevalence of PCOS is increasing world-wide. This could have a disastrous outcome on health since it is linked with multiple noxious comorbidities. Hence management or treatment should be done at the earliest without any unnecessary delay as it can end up in social stigma. Result: Management and treatment of Polycystic ovary syndrome via either of Allopathic, Unani or Ayurvedic systems show a good outcome, for it addresses multiple issues linked to the said disorder whether of genetic or metabolic background. Disorders like hyperandrogenism, anovulation, insulin resistance or hyperinsulinemia, and polycystic ovarian morphologic features in adolescent and adult females are all intervened properly. Conclusion: The majority of women are ignorant of this pathological condition and even the health care professionals are not much familiarized with these comorbidities linked with the condition. The majority of people lack behind in the treatment with the allopathic system because of its tremendous adverse effects, so here based on patients' choice and will, the patient can opt for Unani or ayurvedic system instead, with least or nil side effects and with complete fruitful outcomes.


ABSTRACT Many interventions were introduced using holistic concepts to scale building conformity with sustainability concepts, such as rating systems. Most rating systems efficiently tackled scoring each environmental impact solely at an instance of the building life cycle. However, interaction of different sustainability parameters over complete building life cycle is barely considered. This research presents an initial attempt towards using the behaviour of sustainability parameters over time as a tool for measuring and evaluating building sustainability. This work focuses on studying the interactions between sustainability parameters throughout building life cycle using system dynamics concept. The study's framework includes three main phases: 1) parameters selection, 2) modelling building life sustainability, and 3) policies evaluation. The study introduces Building Sustainability Level (BSL) as a key parameter for evaluation together with some additional Prevailing Parameters (PPs) such as water consumption. BSL provides good representation of expected building sustainability performance, which showed slight unstable behaviour due to initial adoption of sustainability concepts through early years followed by a dramatic growth then a rational rise through the rest of the building life. Moreover, behaviours associated with PPs indicated that most preservation actions impose steady impact through the building life with less sensitivity to change in its magnitude. The study indicates that sustainability parameters behaviours provide good grounds for measuring sustainability, mainly when giving special attention to parameters interaction rather than individual influence. In addition, the tool developed is capable of providing an indication for building future performance and investigating different interference scenarios.


A basic question m the area of asynchronous computation is. Given a synchromzaUon problem, what synchromzation primitives are needed for an "efficient" solution9 This paper is directed toward answering this question by providing characterizations of those synchronization problems solvable by DIjkstra's PV system of primitives and its various generalizations including PVgeneral, PVmultlple, PVchunk, Vector Addmon, and Loopless Penn Net systems These characterizations form the foundations of a formal synthesis procedure for determining effioent solutions to synchronization problems


This is the first case, hitherto described, of benign essential gammopathy, presenting symptoms and histological evidence of peripheral neuropathy. Furthermore, in no previous case, has a specific localization of immunoglobulin (type IgM) to the areas of nerves involved by the lymphocytes been demonstrated. After six months' treatment with chlorambucil the neurological symptoms disappeared and in a biopsy from the right n saphenus no endoneural lymphocytes or local IgM could be found.


-GOETHE, Iphigenie, III, 2 (1306-9) These four lines have been described as the most difficult passage of the play.' The everlasting punishment of Tantalus strikes a discordant note in Orestes' vision of peace and reconciliation as he emerges from the state of unconsciousness brought on by his spiritual and physical collapse. His imagination pictures the royal house of Atreus a united and reconciled family. Thyestes and Atreus walk side by side in familiar converse. Agamemnon leads Clytemnestra fondly by the hand. Orestes is himself welcomed into their midst as the long-lost son. But Tantalus, the progenitor of the race, is missing, and Orestes ascribes his absence to the unrelenting vengeance which the gods have wreaked upon his unfortunate ancestor. Critics have attempted to explain this apparent incongruity on moral and religious grounds with the help of the traditional account of Tantalus' downfall and expulsion from Olympus.2 Kuno Fischer holds that Tantalus was the only member of the race who had sinned against the gods themselves, whereas the crimes of the descendants were committed against men.3 This interpretation scarcely agrees with the conception underlying the play that the gods are conciliatory and ready to pardon the truly repentant sinner. Frick4 suggests that Tantalus' rebellious spirit was still unbroken and that the gods could not pardon him until he had submitted to their higher will. Both these critics have overlooked the important fact that throughout the play Goethe suits his own convenience in his treatment of the ancient story and Greek mythology. He would by no means feel obliged to reproduce for its own sake the


Based on increasing resistance of stored grain insect pest to chemicals and decreasing fumigants, the effects of ethyl formate (EtF) on eggs, early larvae, late larvae, pupae and adults of Sitophilus oryzae were systematically studied with the sealed jar fumigation method under different conditions. The corresponding corrected mortalities of adults were 90.541% and 99.324% with 40 and 45μL/L EtF dosage and 12h fumigation under 25℃. Under the conditions of 24h fumigation with 30μL/L dosage at 19, 25, and 31℃, the adult corrected mortalities were 83.108%, 62% and 42%, respectively. These results indicated that the EtF killed the adult weevils in a very short time period, and the fumigation efficacy at relatively lower temperature was better than that at relatively higher temperature. Under the conditions of 20, 25, 30℃ and 24h fumigation, the LC_ 50 s were 25.094, 28.650 and 30.875μL/L, respectively, whereas after 48h fumigation, the corresponding LC_ 50 s were 23.101, 25.805 and 27.316μL/L. Fumigated the immature stages of S.oryzae 24 h with 30g/m3 dosage EtF, the mortalities of eggs, early larvae, late larvae and pupae of were 96.930%, 99.333%, 97.768% and 93.386%, respectively, which proved that the fumigation activity of EtF against early larvae was the best, and the pupae and eggs possessed a relatively high endurance to EtF.


2 LIST OF FIGURES 4 LIST OF TABLES 4 GLOSSARY 5 1.INTRODUCTION 1.1 Topic Outline 6 1.2 Research Aims and Questions 6 2. METHOD 2.1 Definitions 7 2.2 Field Of Investigation 7 2.3 Spatial Units for Analysis 7 2.4 Choice of Travel Modes 7 2.5 Part 1: Spatially Locating Potential Deserts And Their Relative Severity 7 2.5.1 Data Sets and Shape Files 8 18.104.22.168 Geocoding The Supermarket Database 8 2.5.2 Developing The Framework For Public Transport Analysis 9 2.5.3 Devising the GI 10 22.214.171.124 Numerator: Determining 'Attractiveness' 10 184.108.40.206 Denominator: Determining The 'Travel Parameters' 11 2.5.4 Interpreting The GI 11 2.5.5 Dealing with Problematic Records 11 184.108.40.206 Correction Process 12 2.6 Part 2: Car Captivity Is The 'Desert-i-Ness' A Problem? 14 2.6.1 Data Set 14 2.6.2 Integrating Car Ownership Rates 15 3. RESEARCH FINDINGS 3.1 Transit Captivity By Mode 17 3.1.1 Walking 17 3.1.2 Trams 21 3.1.3 Driving 23 3.2 Integrating Car Ownership With Accessibility 26 3.2.1 Identifying Car Ownership Across the MSD 26 3.2.2 Walking 28 3.2.3 Trams 31 3.2.4 Driving 34 4. DISCUSSION AND CONCLUSION 37 4.1 Broad Findings 37 4.2 Conclusion and Future Research 37 5. REFERENCES 38


This article, written by JPT Technology Editor Chris Carpenter, contains highlights of URTeC paper 208395, "Integration of Pressure-Transient and Fracture Area for Detecting Unconventional-Well Interference," by Mazher Ibrahim, SPE, Matt Sinkey, SPE, and Thomas Johnston, SPE, Shear Frac Group, et al. The paper has not been peer reviewed.
 Hydraulic fractures created during completions are assumed to produce back to the original well. While multiwell-pad completions increase efficiencies, they complicate fracture connectivity between wells. The proximity of newly completed wells to a pre-existing producing well suggests a depleted zone that can "steal" fracture surface area. The complete paper presents a real-time method to estimate the stage-to-stage interference and well-to-well interference and their implications on completions efficiency.

 The primary challenge for the industry with regard to unconventional resource development is to optimize well spacing to improve well net present value. Shale heterogeneity and completion design influence fracture orientation and geometry. The industry still lacks accurate methods in characterizing these.
 Fig. 1 shows three well-spacing types that the authors write could be classified as "good," "bad," or "ugly"—the A+ spacing type (good), the B spacing type (bad), and the C spacing type (ugly).
 The A+ spacing type has no interference between wells that perfectly drain the reservoir; however, it is hard to achieve. In the B spacing type, there may be 10–15% interference between either hydraulic or natural fracture systems. B spacing can be achieved with proper integration of reservoir and completion engineering. This spacing type usually can provide more predictable well-level estimated ultimate recovery (EUR). C spacing type is characterized by closer-than-needed spacing, resulting in shared stimulated reservoir volume (SRV) between wells. Some operators use this spacing when oil and gas prices are high in order to accelerate production.


The Low voltage high accurate current mode analog multiplier is a basic building block in analog signal processing. This proposed circuit is a four quadrant multiplier, designed using squarer circuit. The squarer circuit is designed based on the translinear loop principle. The major advantages of proposed design are low voltage (VDD=1V), high accurate, high bandwidth (122MHZ), less area, and small linearity error. The linearity error is obtained as 0.5%. The simulations of circuit are done in the pyxis schematic editor using Mentor graphics tool with 0.18μm standard CMOS technology.


The techniques of enzyme cytochemistry have been applied to a study of aspirated and smeared malignant cells and to bone marrow cells. Analysis of the enzyme activity of cells from 240 specimens was carried out. By determining characteristic enzyme activity patterns with 4 enzymes, namely acid and alkaline phosphatase, aminopeptidase and nonspecific esterase, it has been possible to derive patterns for a number of tumors which can aid in the diagnosis of the primary site of origin of metastatic lesions. Distinction between anaplastic carcinomas of some types and lymphoreticular sarcoma is possible on the basis of enzyme studies. Similar distinctions appear to be true for lung and genitourinary tract carcinomas but it was not feasible to determine a general method to distinguish all anaplastic carcinoma from sarcoma. Further study of the diagnostic value of this technique appears to be warranted.


This article studies the relation between these twophilosophers. First, it shows that Hume does not attack directly Spinoza's ideas, but rather the conception held by theologists conceming the simplicity and the inmortality of the soul.
Hume denies substances because he considers that a substance is an unknown substratum, in which al1 qualities inhiere, something simple, unchangeable and perfectly identical through time. However, it is pointed out that Spinoza's conception of substance is not exactly the same as Hume considers.
Recent articles are commented which have been published on different aspects that these two philosophers have in common.


China's higher vocational education is developing rapidly in recent years.But the management work of student education in vocational colleges is still at the primitive stage.With personal work experience,the author presents the study according to the situation and characteristics of present vocational college students.


Acknowledgements: I would like to thank Scene Consulting, in particular, Anna Harnmeijer, Vijay Bhopal and Jelte Harnmeijer for valuable mentorship and an opportunity to develop a keen interest in development. A second thanks to Jelte Harnmeijer, my supervisor, for his guidance during the time of my dissertation research. Lastly, I am immensely grateful to my friends and family for all their precious support. A CRITICAL COMPARISON OF CASHAND ASSET-BASED MICROCREDIT IN ALLEVIATING POVERTY


The prospect of international conflict over water has long been the subject of academic and popular concern, but subnational political conflict is considerably more common, and almost certainly imposes greater economic and environmental costs. Indeed, subnational hydropolitics are an important feature of several large countries, including the United States, India, and China. Moreover, disputes between water users in shared river basins have often persisted despite repeated attempts by central governments to resolve them through both persuasion and coercion. Yet despite the growing threat of water scarcity around the world, little research exists on sub-national politics of shared water resources. This book attempts to fill the gap by explaining how and why hydropolitics play out within countries, as well as between them. Subnational Hydropolitics re-examines the issue of water conflict by examining conflicts at the subnational rather than international level. By examining several in-depth case studies of both conflict and cooperation, Scott Moore argues that increasing sub-national water conflict is driven by two inter-linked forces, identity politics, which gives subnational politicians a reason to compete over shared water resources; and political decentralization, which provides them with the tools to do so. To understand politics at the subnational level, the book blends insights from both the environmental governance and comparative politics literatures. By examining the challenges many countries face in achieving cooperation over shared water resources, the book helps to shed light on different mechanisms and processes for solving cooperation problems at the regional scale lessons relevant to tackling a wide range of transboundary environmental problems, including air pollution, urbanization, and ecosystem protection. But at its core, this book promises a definitive contribution to the growing sub-field of environmental politics, centered on understanding how different countries attempt to solve the problems inherent in governing water resources in shared river basins.


Weakly nonlinear internal waves are considered in a non-Boussinesq inviscid incompressible flow using Long's equation. The waves are bounded on the top and the bottom by horizontal rigid surfaces, and are periodic in the horizontal. A Laurent-type expansion in the wave amplitude is chosen, which eliminates the problem found with the traditional Taylor expansion of progressively faster exponential growth with altitude of the higher harmonics. The results show that the second-order correction to the wavespeed can be positive or negative, depending on the wave parameters. The final wave envelope has the shape of a saturated wave.


The aim of the present study was to determine if nitric oxide (NO) acting on the brain of the tegu lizard Tupinambis merianae presents an inhibitory effect on arterial blood pressure (ABP) and heart rate (HR) by reducing the sympathetic activity dependent on α adrenergic receptors. A guide cannula was implanted into brain lateral ventricle for injections of L‐NMMA (non selective NO synthase inhibitor) or mCSF (mock cerebrospinal fluid). A catheter was inserted into the femoral artery for ABP record and another one in the femoral vein for injections of α1‐adrenergic antagonist (prazosin) and agonist (phenylephrine) or saline. Experiments were conducted during spring (activity) and winter (hibernation) at 24–27°C to abolish temperature effect on ABP and HR. Basal ABP (mmHg) and HR (bpm) were, respectively: 35.2 ± 3.2 and 10.4 ± 1.5 (winter); 31.6 ± 1.5 and 11.8 ± 1.0 (spring). No seasonal variation of the basal values was observed. L‐NMMA increased ABP and HR in both seasons (P< 0.05), an effect that was more prominent during spring. The pre‐treatment with prazosin inhibited the hypertensive and taquicardic effects of L‐NMMA in both seasons. The effectiveness of prazosin was confirmed by the blockade of phenylephrine effects. We conclude that NO seems to act on the brain of tegus as a hypotensive agent via a mechanism dependent on α adrenergic receptors in the periphery. Supported by FAPESP and CNPq.


Excitation regulator based on dynamo SAVR-2000 is the 2nd microcomputer excitation regulator,combined classical and modern control theories with DSP technology of digital signal processor.It inherits and develops the 1st mi- crocomputer excitation regulator with functions in all regulation,control and restriction and protection,making a great deal of progress in computing speed,resistance to electromagnetic interference and reliability and so on.All that credit it a better excitation regulator among modern large and medium-sized synchronous generator groups.SAVR-2000 is applicable to all kinds of thyristor excitation with high commonality.It is proved a updated product by excitation experts.


Objective:To compare the efficacy of tramadol with that of morphine in patient-controlled epidural analgesia (PCEA) after esophageal carcinoma surgery through thoracoabdominal incision.Methods:60 patients undergoing esophagogastrostomy were randomly divided into two groups with 30 cases each.Patients in group T were given tramadol 600mg,ropivacaine 250mg,dropiridol 5mg and 0.9%NaCl diluted to 200ml;and patients in group M received morphine 30mg,ropivacaine 250mg,dropiridol 5mg and 0.9% NaCl diluted to 200ml.Loading dose of each group was 5ml,and background infusion 2ml/h,bolus 0.5ml,lockout time 15 minutes.The visual analogue scale (VAS) ,sedation scale (SS) ,side effects and patient's satisfaction were assessed.Results:VAS,SS showed no difference in both groups(P0.05).83% patients obtained adequate analgesia in both groups (25/30 in 24h,VAS3).The incidence of nausea and vomiting in group M was higher than that in group T(P0.05).Conclusion:Tramadol can provide the same and satisfied effect as morphine after thoracolaparotomy,and the incidence of nausea and vomiting in group T is lower than that in group M.


Studies  concerning  socioeconomic  and medical  problems  of  the  elderlies  in  Khon  Kaen  Province,  Northeast  Thailand,  were  conducted  in  1989 – 1990.  The  objectives  of  these  stuidies  were  to  out  nutritional  status,  eating  habit  and  parasitic  infection. A  tobal  of  464  elderly  persons  from  a  semi – urban  area  and  a  rural  area   of  Khon  kean  Province  were  sampled  by  the  30  cluster  sampling  technique  in  each  area, The  method  was  composed  of  an  interview  by  structured  questionnaire,  an  in – depth  interview,  a  24 – hour  recall  interview,  stool  examination  and  anthropometry  by  height  and  weight   measurement. The  results  revealed  theat  most  of  elderly  lived  with  their  relatives  and  or  children  and  had  been  taken  care  by  their  elotives. Half  of  the  tobal  elderlies  were  widwed  and  primary  school  educated ;  and  22.4  per  cent  were  working ;  66.3  percent  were  smokers  and  most  of  them  were  males ;  37.1  per  cent  were  drinkers.  Seventy – six  per  cent  of  the  total  elderly  group  habitually  chewed  areca   nuts  and   betel  leaves  smeared  with  lime  ;  36.4  per  cent  consumed  improperly   cooked  food. IIIness  prevalence  of  elderly  during  the  previous  2  weeks,  was   fond  that  the  number  of  sick  elderly  in  the  semi – urban  area  was  slightly  higher  than  those  in  the  rural  area. Curative  behavior  or  health  seeking  behavior  when  getting  ill  of the  elderly  was  found  as  following  :  42.2  percent  went  to  see  a  doctor  at  the  health  station  or  clinic  and 39  percent  had  self  medication. Nutritional  status  of  the  elderly,  using  body  mass  index  (BMI)  calculated  from  weight  and  height  revealed   that  rural  elderlies  were  lean  significantly  much  more  than those in  semiurban  aaea. (BMI <  20  kg / m 2 ) During  24  hours  prior  to  a  recall  interview,  more  than  one – third  of  the  elderly  consumed  protein,  calcium,  vitamin  B 1 and  B 2 in  less   than  the  recommended  amounts. The  highest  prevalence  rate  was  for  liver  fluke  (Opisthorchis  viverini).  Hookworm  and  minute  intestinal  flukes  were  the  second  and  third  most  common  prasitic  infections.  The  prevalence  of   parasitic  infections  more  than  one  kind  of   parasite  in  the  lederly  in  the  rural  area  was  significantly   higher  than  in  the


The performance of document clustering systems depends on employing optimal text representations, which are not only difficult to determine beforehand, but also may vary from one clustering problem to another. As a first step towards building robust document clusterers, a strategy based on feature diversity and cluster ensembles is presented in this work. Experiments conducted on a binary clustering problem show that our method is robust to near-optimal model order selection and able to detect constructive interactions between different document representations in the test bed.


The problem of binary data format specification is considered. This problem is further limited to simpler subproblems. First, the concept of specification of data interpretation as opposed to specification of data modification is introduced, i.e. we shall concentrate on the interpretation of already existing static data, and will not take into account different aspects of memory allocation, correct sequence of data elements and so on. Next, we shall consider the case of data type identification, which is a special and most basic kind of data interpretation. Specification of the data type identification for some data format enables to identify every bit of data of this format as a part of representation of some data element of definite type. The language of Flexible Types FlexT was developed for description of the data type identification. It uses rather simple extensions of the set of type constructors traditional to common procedural languages. These extensions are very efficient for the problem under consideration. On the one hand, the use of specification when developing a program enables to increase the safety of the program due to increase of the level of abstraction of the specified program part. On the other hand, the specification of format of some data enables to increase the reliability and safety of processing of this data, because it makes them transparent. I.e. specification of data format enables to consider the data not as a ''black box" a sequence of bytes of unknown purpose, but as a collection of data elements of definite types, which makes it possible to control the contents of the data. We can also consider a machine code as a specific type of data and describe file formats like that of EXE and OBJ files. Key-Words: binary format, formal specification, data format specification, specification of data interpretation, specification of data modification, data type identification. CSCC'99 Proceedings, Pages:1371-1376


The authors study the retrieval properties of Hopfield's model (1982) when there is a finite correlation between two of the memorised patterns.


The context for innovation has changed over the past decade: OECD economies are increasingly dependent on innovation to remain competitive; the innovation process is more open and increasingly involves collaborations within and across borders; ICTs have become a key driver of innovation in all industries; and new global players have emerged. In this context, a major challenge for governments is to tap into and exploit global networks to access new knowledge and markets while generating value locally.


Compassion fatigue is a problem many frontline workers face. It presents in the form of sleep troubles, intimacy issues, and general anxiety and depression as a result of working with individuals who have experienced trauma firsthand. As applied anthropology becomes more involved on the frontlines, researchers risk experiencing symptoms similar to those that others who work in these fields have faced. I explain how I encountered compassion fatigue through the literature as well as through real-world experience in an internship with a suicide hotline and domestic violence shelter. I then provide solutions for preventing compassion fatigue in applied anthropological research, suggesting that we might be able to impact other frontline workers as well.


A new idea to model long-term correlations in broadband speech and audio coders based on regular pulse excitation is presented. It involves expanding the excitation sequence with additional pulses targeting this type of correlation while being bit rate efficient. Comparison with the standard method (long-term prediction) highlights the advantages of the proposed technique.


Mechanical behavior and microstructural stability of the high-nitrogen austenitic stainless steel 18%Cr-12%Mn-0.55%N at room/low temperature were investigated with its fracture mechanism discussed. Charpy impact test result showed that the ductile-brittle transformation of the steel specimens takes place at about -70 ℃ and a cleavage-like fracture happens along the {111} facet of austenitic matrix. Furthermore,the tensile test result indicated that a deformation-induced phase transformation happens even at room temperature,from which the products include α' martensite and the other one whose structure and relevant parameters cannot be ascertained yet. Based on both the results,it is found that the steel has a good combination of high strength with favorable ductility when it is used at over -60 ℃.


Simple Summary Our growing aging population and increased prevalence of obesity have become an emerging health problem as these conditions lead to the development of related diseases. Specifically, obesity and aging are associated with cardiovascular disease and a decline in cognitive function underlying the inflammatory mechanisms. However, the literature regarding how both interact and impact these complex physiological processes across the lifespan remains to be elucidated. As such, this review discusses how obesity in aging adults mediates inflammatory, cardiovascular, and neurobiological effects of exercise in this population. Abstract Obesity with advancing age leads to increased health complications that are involved in various complex physiological processes. For example, inflammation is a critical cardiovascular disease risk factor that plays a role in the stages of atherosclerosis in both aging and obesity. Obesity can also induce profound changes to the neural circuitry that regulates food intake and energy homeostasis with advancing age. Here we discuss how obesity in older adults impacts inflammatory, cardiovascular, and neurobiological functions with an emphasis on how exercise mediates each topic. Although obesity is a reversible disorder through lifestyle changes, it is important to note that early interventions are crucial to prevent pathological changes seen in the aging obese population. Lifestyle modifications such as physical activity (including aerobic and resistance training) should be considered as a main intervention to minimize the synergistic effect of obesity on age-related conditions, such as cerebrovascular disease.


We design forward and backward fault-tolerant conversion circuits, which convert between the Steane code and the 15-qubit Reed–Muller quantum code so as to provide a universal transversal gate set. In our method, only seven out of a total 14 code stabilizers need to be measured, and we further enhance the circuit by simplifying some stabilizers; thus, we need only to measure eight weight-4 stabilizers for one round of forward conversion and seven weight-4 stabilizers for one round of backward conversion. For conversion, we treat random single-qubit errors and their influence on syndromes of gauge operators, and our novel single-step process enables more efficient fault-tolerant conversion between these two codes. We make our method quite general by showing how to convert between any two adjacent Reed–Muller quantum codes RM¯(1,m) and RM¯(1,m+1), for which we need only measure stabilizers whose number scales linearly with m rather than exponentially with m obtained in previous work. We provide the explicit mathematical expression for the necessary stabilizers and the concomitant resources required.


Dennis W. Hostetler of Collinsville, professor emeritus of public administration and policy analysis, died December 31, 2010, after a long illness. He was 68.


The unifying element throughout the book is the concept that dominant characteristics of organization and management today are an evolution from the principles and technique of Frederick W. Taylor, &dquo;Father of Scientific Management,&dquo; as influenced by those immediately or remotely associated with him and by creative students of his writings. The evolution is traced chiefly in terms of individuals. Following a comprehensive and understanding analysis of Taylor's revolutionary technique, which serves throughout as an unobtrusive base of reference, the author analyzes the contributions of Henry L. Gantt, Frank B. and Lillian Gilbreth, Harrington Emerson, and Morris L. Cooke. Following a summary evaluation of the influence of this group, attention is given to subsequent contributions in the United States; and in Europe, notably of Henri Fayol. The second half of the book is concerned with extension of the boundaries


BACKGROUND
Cancer initiation and progression are controlled by genetic and epigenetic events. One epigenetic process which is widely known is DNA methylation, a cause of gene silencing. If a gene is silenced the protein which it encodes will not expressed.

OBJECTIVES
1. Identify the methylation status of BRCA1 in patients with epithelial ovarian cancer (EOC)and assess BRCA1 protein expression in tumor tissue. 2. Examine whether BRCA1 gene methylation and BRCA1 protein are associated with survival of epithelial ovarian cancer patients.

METHODS
The study design was a prospective-cohort study, conducted at Sardjito hospital, Yogyakarta, Indonesia.

RESULTS
A total of 69 cases were analyzed in this study. The data showed that the methylation status of BRCA1 in EOC was positive in 89.9%, with clear protein expression of BRCA1 in 31.9%. Methylation status and expression of BRCA1 were not prognosticators of EOC patients. Menarche, CA125 level, clinical stage and residual tumor were independent factors for prognosis.


Business internships have become increasingly important and popular in students' learning and career preparation. We conducted a study among eighty-eight business interns to understand the level of satisfaction that marketing students experience from completing internships. Using a factor analysis, this study identified several factors relevant to students' satisfaction with internships. Several hypotheses were proposed linking relevant factors and satisfaction with internships. Students' satisfaction with their internships was found to be related to nature of the internship experience and the benefits received. Based on the findings of this study, some implications were drawn for the students and universities.


We present a new all-optical broadcast LAN architecture and an accompanying signaling protocol. The design, verified in a partial hardware emulation, is fault-tolerant and collision-free, allowing it to achieve high throughput in a broadcast environment.


We propose a numerical scheme to compute the motion of a two-dimensional rigid body in a viscous fluid. Our method combines the method of characteristics with a finite element approximation to solve an ALE formulation of the problem. We derive error estimates implying the convergence of the scheme.


In the past, humanists and scientists have held very different views about the role of collaboration in scholarly research. From the point of view of a Principal Investigator in a scientific laboratory, this article examines the increasingly dominant role of collaboration in scientific research. In contrast to the 'consensus research' model of the sciences, humanists have often viewed the role of collaboration in research with considerable skepticism and have placed greater value on the traditional model of the solitary scholar pursuing knowledge and truth. An examination of some of the distinctive cultural differences between the humanities and sciences suggests that the benefits of collaboration may come to play an increasingly significant role in the future of humanistic research.


The Lausanne Movement makes very clear what the purpose and aim of theological education should be: to train and equip missional leaders who can guide the lay people in the church to participate in God's mission in their everyday lives. With churches from non-Western cultures acquiring a heightened status as major actors in the process of world evangelization, the following question must be addressed: what kind of theological education should the non-Western churches pursue? The answer, to echo the overarching argument of the Lausanne Movement, lies in allowing indigenous believers to actively interpret the Scripture and develop context-related theological education rather than accepting pre-existing, Western forms of theological education.


A succinct expression and cycl integrating no the sum of equal powers are obtained here and the value of the formula B 1~B 1000  is given.Solving pogram (Maple7)is to provide for you.


Azimuth multi-channel (AMC) synthetic aperture radar (SAR) is an effective technology to conquer the minimum antenna area constraint and can provide high-resolution and wide-swath (HRWS) SAR images compared with the conventional strip-map SAR. In order to suppress azimuth ambiguity, AMC SAR will face an important problem: channel imbalances estimation and compensation. At first, this paper theoretically analysis the effects of channel imbalances including amplitude imbalance, phase imbalance and range sampling time imbalance (RSTI) on AMC SAR images, where all these channel imbalances will introduce false targets in azimuth, and RSTI will also make a significant influence on the range of SAR images. And then, in order to validate the above result, some simulations based on the parameters are carried out, and the real image acquired by GF-3 is also described. In addition, the intensity, number, and position of false targets are discussed. Finally, this paper makes some conclusions and points out the problems of these results.


The ability to navigate and comprehend online informational text is essential for 21st century learners. It requires orchestrating a mix of old and new reading strategies--and it's easy for teachers and students to feel overwhelmed! This column describes a way of combining student screencasting with Reciprocal Teaching to help students--and teachers--slow down and more deeply explore and understand the component skills of online informational reading.