viewed as the most valid models for understanding cognitive deficits and their neurobiological substrates in the elderly. Grey mouse lemur, Microce-bus murinus, shows age-related changes similar to those of aging humans, and some older mouse lemurs show evidence of Alzheimer's pathology, e.g. amyloid plaques (Languille et al, 2012). The aim of this study is 1) to identifyanimalswithage-relatedcognitivedeficit,2)toinvestigate potential detection of blood biomarkers of neurodegenerative progression. Methods: Young (n ¼ 13), middle-aged (n ¼ 16) and old (n ¼ 12) male mouse lemurs were tested in hang and balance tasks, in open field and plus-maze tests, in spontaneous alternation task, novel object recognition test and in the Barnes maze test. APPholoprotein and the 55kDa-APP-CTF bands were determined from platelets by Western blot in 15 males of different ages. Results: Psychomotor capacities and anxiety-related behaviors decreased abruptly from middle to late adulthood. Mnesic functions were unequally affected with aging. Whereas spontaneous alternation task suggested a pro- gressive and widespread age-related decline of spatial working memory, both spatial reference and novel object recognition memory tasks revealed a large individual variability in the middle-aged and old animals. Hierarchi-cal clustering analysis revealed that episodic-like memory was strongly impaired only in 7 middle-aged/old animals. Biomarkers of diseaseprogres-sion were successfully detected in blood. Results show high inter-individual variability especially around middle-age with no clear relation to cognitive status. Conclusions: These behavioral data offer the opportunity to distin- guishnormaland neuropathological aging in this non-human primatemodel as compared to human aging. Successful determination of blood biomarkers opens perspective for long term follow up and correlative approach of the neurodegenerative progression in a non human primate species. This re- search met ethical requirements of the EC Council Directive (2010/63/ UE) and was part of the PharmaCog consortium. Background: Age-related Alzheimer's disease (AD) is the most common form of dementia and directly affects several cognitive domains crucial for daily functioning, such as attention or memory. Current pharmacother- apy is focused on the improvement of these different symptoms. Within this context, preclinical research using models for the study of age-related disorders is crucial for the development and improvement of pharmacolog-ical strategies. Sleep deprivation (SD) is a validated model to induce tempo- rary cognitive impairment. The O. degus has been recently proposed as a potential preclinical model relevant for neurodegenerative diseases. This rodent presents some advantages over other models including rats and triple-transgenic mice, which make it a promising alternative for such studies. One of the actual compounds registered to treat cognitive symptom-sis memantine. Thus, we therefore studied the effect of memantine on cog- nitive impairment induced by SD in the O. degus. Methods: To this aim, we trained and tested the animals in different behavioral paradigms validated for memory evaluation: the Radial Arm Maze, and the Novel Object Recognition test. Before the test, we assigned the animals to a control (CTL, n ¼ 8) or an SD (n ¼ 8) condition. SD was performed following a gentle handling procedure. Animals were treated with vehicle or 10-mg/kg of memantine (IP) before the dark cycle started. Results: Our results showed that memantine (10 mg/kg) had no effect on CTL animals while it effectively prevented the cognitive impairment caused by SD in the different cognitive domains evaluated. Conclusions: The positive effect of memantine in counteracting SD in this species further support the potential of both the challenge and the species as a promising model with translational properties, and will enable a better understanding of the behavioral features of memantine's effects. Background: Alzheimer's disease is one of the most disabling and burden- some health conditionsworldwide.Insulin contributes to normalbrain func-tioning and peripheral insulin abnormalities increase the risk for memory loss and neurodegenerative disorderssuch as Alzheimer's disease. Epidemi-ological studies on cognitive impairment in patients with diabetes found evidence of cross sectional and prospective associations between type 2 diabetes and moderate degree of cognitive impairment, both for memory and executive functions. Several studies suggest that consumption of a fat rich diet leads to peripheral insulin resistance and impede cognitive perfor- mance. Insulin resistance is associated with an increase in circulating advanced glycosylation end products (AGEs) and the increased expression of the receptor for AGEs (RAGE). Fructose has been reported as a potent agent in forming AGEs and, thus, may play a significant role in the develop- ment cognitive function. Thus, the present study was designed to develop fructose-induced insulin resistance associated Alzheimer's disease and fur- ther to elucidate the possible neurogenic relationship between two clinical entities. Methods: Six-week-old male Wistar rats were fed with 15% fruc- tose in drinking water for 24 weeks. Body mass, food and water intake were measured regularly. Insulin resistance associated cognitive impairment was measured by using Morris water maze test (computer tracking using EthoVision software) and elevated plus maze on 14th, 16th, 20th, 22nd and 24th weeks. At the end of study, animals were sacrificed for estimating biochemical and molecular parameters. Results: Insulin resistance was evident at 6th week and persisted till end of study (24th week) as demon-strated by significantincrease in body weight, plasma insulin levels, blood glucose levels, glycosylated heamoglobin levels,HOMA-IRlevelsand deranged lipid profile.Cognitive deficit was significantly evident at 20th, 22nd and 24th weeks. This time-dependent study suggested emergence of insulin resistance-induced memory impairment after 20th weeks of fructose consumption. Fructose-induced neuronal deficits were coupled with signif-icant alterations in oxidative-nitrodative stress, inflammatory cytokines (TNF- a ,TGF- b )andgrowthfactors(NGFlevels). Conclusions: Thesefind-ings indicate that chronic fructose consumption generated a condition of- neuronal insulin resistance. Impairment in neuronal insulin response


of noninferiority and equivalence randomized trials: an extension of the CONSORT statement. JAMA 2006; 295:1152–60. 14 Rose SB, Lawton BA. Impact of long-acting reversible contraception on return for repeat TOP. Am J Obstet Gynecol 2012; 206: 37.e1–6. 15 Cameron ST, Glasier A, Dewart H, Johnstone A, Burnside A. Telephone follow-up and self-performed urine pregnancy testing after early medical TOP: a service evaluation. Contraception 2012;86:67–73. 16 Aubeny E, Peyron R, Turpin CL, Renault M, Targosz V, Silvestre L, et al. Termination of early pregnancy (up to 63 days of amenorrhea) with mifepristone and increasing doses of misoprostol [corrected]. Int J Fertil Menopausal Stud 1995;40(Suppl 2):85–91. 17 Peyron R, Aubeny E, Targosz V, Silvestre L, Renault M, Elkik F, et al. Early termination of pregnancy with mifepristone (RU 486) and the orally active prostaglandin misoprostol. N Engl J Med 1993;328:1509–13. 18 Elul B, Hajri S, Ngoc NN, Ellertson C, Slama CB, Pearlman E, et al. Can women in less-developed countries use a simplified medical TOP regimen? Lancet 2001;357:1402–5.


We consider a two-sided one-to-one abstract matching problem with a defined notion of pairwise stability. The formulated problem is shown to encompass the ordinal and cardinal utility markets. We propose a distributed blind matching algorithm (BLMA) to solve the problem. The BLMA is characterized by random activations of agents, and by generic negotiation and aspiration (utility) update processes. We prove that the solution produced by the BLMA will converge to an <inline-formula> <tex-math notation="LaTeX">$\epsilon$ </tex-math></inline-formula>-pairwise stable, equivalently <inline-formula> <tex-math notation="LaTeX">$\epsilon$ </tex-math></inline-formula>-core, outcome with probability one. We then consider three BLMA applications in cognitive radio networks. We propose a simple BLMA negotiation and aspiration update dynamic to produce an <inline-formula> <tex-math notation="LaTeX">$\epsilon$ </tex-math></inline-formula>-pairwise stable solution for the case of quasi-convex and quasi-concave utilities. In the case of more general utility forms, we show another BLMA process to provide equilibrium. We also consider the use of the BLMA in an ordinal utility market. In all applications of the BLMA, we impose a limited information exchange in the network so that agents can only calculate their own utilities, but no information is available about the utilities of any other user in the network.


Despite advances that have greatly improved the overall survival of pediatric B cell acute lymphoblastic leukemia (B-ALL), it remains one of the leading causes of cancer-related death in children. Immunotherapy has shown efficacy in treatment of refractory disease, highlighting the need for greater understanding of the immune evasion mechanisms underlying this disease so that additional immune modulating therapeutic strategies can be developed.
 Siglec-15 (Sig15) was recently reported to have immune modulatory functions in the context of solid tumors. We have found that SIGLEC15 is overexpressed at the RNA level in primary B cell acute lymphoblastic leukemia (B-ALL), acute myelogenous leukemia (AML), and diffuse large B cell lymphoma as compared to healthy donor controls. As compared to healthy donor PBMCs, we have confirmed higher expression of Sig15 at the RNA and protein levels through RT-qPCR, immunoblotting, and flow cytometry across a panel of human B-ALL, AML, DLBCL, and T cell acute lymphoblastic leukemia (T-ALL) cell lines. Knockout of Sig15 expression in a BCR-ABL1+ murine model of B-ALL engrafted in immunocompetent and Rag1-/- immunodeficient recipients resulted in leukemia clearance in immunocompetent, but not immunodeficient, recipients and 100% survival (Figure 1). These data suggest a prominent role for Sig15 in the suppression of adaptive immune response to B-ALL as well as other hematological malignancies.
 Additional studies suggest that SIGLEC15 expression is positively regulated by NFκB signaling, which is known to be constitutively activated in certain B-ALL subsets. Importantly, we have observed release of a soluble form of Sig15 (sSig15) from B-ALL cells, which is regulated by PKC and calcineurin-mediated signaling. To discover translational application, we measured sSig15 in the plasma of both healthy and pediatric leukemia patients and found significantly higher levels of sSig15 as compared to healthy individuals (Figure 2; LLD = 5 pg/ml; **P<0.01).
 Together, these results suggest Siglec-15 is a novel and potent immunosuppressive molecule active in leukemia that may be targeted therapeutically to activate lymphocytes against leukemia cells.

 Abukharma: NextCure, Inc.: Current Employment. Liu:NextCure, Inc.: Current Employment.


In the article, on the basis of theoretical generalization and studying the real practice, we have considered an interrelated problem of functioning of legal organizational management forms and modern motivation instruments of staff with the aim of labour capacity increase


The purpose of this study is to trace the evolution of environmental coverage during the 1960s and 1970s, a period that witnessed the passing of the age of abundance and the coming of the age of scarcity. This is done by analyzing the contents of an important and massive segment of the communications system in American society: mass circulation magazines. Each type of magazine and form of reported environmental degradation is discussed and compared to one another. The focal point of discussion is the extent to which mass circulation magazines integrate natural resource issues into their respective areas of specialization.


Taking the thermal design of certain electronic product as an example,this paper uses the thermal analysis function of Ansys software to forecasts the heat distribution and airflow distribution inside the product through simulation analysis.According to the analysis result,this paper optimizes all kinds of design parameters and adjusts the layout,finds the best design project.


A system for facilitating quality inspection V-CUT circuit board comprising an insulating layer and the first and the second copper plating layer is formed on the copper substrate and the side surfaces of the substrate provided on the copper plate on the insulating layer, the copper-clad board comprising layer, the second copper plating layer bonded to the insulating layer; V-CUT defines a line on the first copper plating layer, the circuit board defines two penetrate through the copper plate to the side of the line V-CUT test wells, the test wells filled with conductive material to form the test points; the circuit board further comprises a copper plating layer is formed on the second side of the test line near the insulating layer, the test line is electrically connected two test points, and the test line through the V-CUT. The present invention further provides a method of testing a circuit board. Since the circuit board has a test line is formed on the second copper plating layer, in the V-CUT, by measuring whether the test line is turned on, it can be determined whether the V-CUT to cut the second copper plating layer.


Pitch range is currently characterised in a number of different ways across research disciplines and is often treated as a simple measurement. Pitch range has been defined as the difference between minimum and maximum fO (Cosmides 1983). This data alone conveys no information about the distribution of fO values within that range. Similarly the mean and standard deviation does not adequately capture important differences in the pitch range of different speakers (Ladd et al. 1985). Ladd (1996) describes pitch range using two partially independent dimensions of variation, that of overall level and span. This idea has been further developed by Shriberg et al. (1996), in a study based on a large corpus of Dutch speech. Given this two parameter model, it is possible to predict target fO values for when speakers raise their voices from fO values at corresponding locations in speech produced normally. This thesis reports on three studies of pitch range variation across speakers. The experiments examine the relation between a two dimensional model of pitch range based on pitch level and pitch span with the perception of various speaker characteristics. The key to our measure of pitch range is that it is based on average data taken from clearly defined linguistic targets in speech. These targets included sentence-initial peaks, accent peaks, post-accent valleys and sentence-final lows. The results show that a pitch range model based on linguistic dimensions of variation better captures variation in listeners' judgements than the well established measures based on speakers' long term distributional properties of fO, such as 4 standard deviations around the mean, 95th-5th percentile and 90th-10th percentile. Most importantly this thesis shows that pitch range can and should be treated as the same entity across various research disciplines extralinguistic, paralinguistic and linguistic rather than the current situation in which pitch range has multiple definitions depending on the particular interest of the respective research discipline.


Sodhi, T., Miao, Y., Brouns, F., & Koper, R. (2007). Supporting the non-expert in the authoring of personalized learning using IMS LD. Proceedings of the ePortfolio 2007 Conference. October, 18-19, 2007, Maastricht, The Netherlands. [See also http://hdl.handle.net/1820/1680 ]


The article deals with the issues of combating corruption from the point of view of the negative impact of this phenomenon on the management system in the internal Affairs bodies. The main periods of development of this type of offenses and measures for their prevention are given in the historical perspective. The text focuses on the measures of legal regulation taken by the country's leadership to improve legislation in this area.


A critical step in developing accurate large signal PHEMT models is the equation used for the gate charge. This paper examines three types of gate charge formulations. Measured versus modeled results at 2, 8 and 16 GHz clearly demonstrate that a two terminal voltage dependent gate charge model provides the best prediction of all the parameters measured, namely : output power, PAE, drain current, harmonic power, and 3rd order intermodulation distortion products Ga.


In this paper we will discuss the implications of small-scale paleoenvironmental change on prehistoric human populations residing in the coastal zone of central California. The subject area is central Monterey Bay; specifically, Elkhorn Slough, an estuary situated midway between Santa Cruz and Monterey, the mouth of which now forms part of the Moss Landing Harbor (Fig. 1). Although the slough is currently classified as an estuary, it has a complex hydrographic past related partially to sea-level rise and partially to other natural events. Over 40 sites have been recorded in the Elkhorn Slough area, all of which can generally be classified as shell middens, with shellfish remains constituting the bulk of cultural deposits. Analysis of data from two of these sites reveals a changing pattern of shellfish exploitation through time which correlates with the slough's hydrographic history.


Digital Microfluidic Biochips (DMFB), a promising platform for Lab-on-chip systems are capable of automated biochemical analysis targeted for medical diagnostics and other biochemical applications. The inherent nature of reconfigurability and scalability enables the device to integrate multiple bioassay protocols within the same array for simultaneous execution. Each execution of Bioassay involves numerous microfluidic operations to be performed successfully within the DMFB. Optical Detection and analysis are one of the significant operations required to be performed in DMFB systems for conclusive diagnosis and testing of targeted parameters within the specified sample. In this paper we propose a new design for automated detection based analyzer system integrated with a multipartioned scalable DMFB for two stage confirmatory detection of multiple parameters for a given set of samples .Multiple bioassays are executed sequentially in two stages and the results are analyzed using an intelligent system with integrated memory containing precharacterized standard outputs. The design prototype is implemented on FPGA platform and the simulations and detection results for a set of specified bioassay protocols are found to be satisfactory and in conformance with conventional benchtop laboratory processes.


The effect of post-harvest treatment of Maleic hydrazide (MH)with and without waxing on the quality and shelf-life of 'Baladi' and'Ekostika I' papaya fruits at 18 ± 1 oC and 85% – 90% relative humiditywas evaluated. Maleic hydrazide at 250 and 500 ppm significantlydelayed fruit ripening by two and three days in both papaya cultivars,respectively, compared with untreated fruits. The higher theconcentration, the more was the delay in fruit ripening. The results alsoshowed that waxing in addition to MH resulted in a delay of two moredays in fruit ripening than treatment with MH alone. The effect of MHand waxing treatments in delaying papaya fruits ripening was manifestedin retarded respiratory climacteric, reduced weight loss and delayed fruitsoftening and increase in total soluble solids and ascorbic acid content


Efficiency and persistence of microfilaricidal actions of baimek and aversect in a doze of 0,2 mg/kg of body weight at setariosis of cattle are investigated. Both drugs have shown 100 % efficiency against microfilaria and inactivity against adults of Setaria labiato-papillosa in cattle.


The world-wide outbreak of Covid-19 effected radical change in most institutions of higher learning. These institutions were forced to adopt any technologies at their disposal to continue with teaching and learning and, during that time, many students and lecturers at rural-based universities adopted mobile instant messaging (MIM) for collaborative learning. This study investigates the impact of MIM for collaborative learning during a Covid-19 lockdown in one rural-based university. Data were collected from both students and lecturers using a closed-ended questionnaire, and analysed using IBM SPSS Statistics. The study found that MIM had a positive impact on collaborative learning in the rural-based university during the Covid-19 lockdown.


Groups are very significant elements of social networks, thus understanding their structure and reasons of their evolution are very important. In this paper a qualitative analysis of group evolution is proposed. The description of this process takes many aspects such as group transformation events, discussed topics and attitude of the discussion participants into consideration.


A GaAs surface treated with pure water was characterized by using contact angle measurement. Auger electron spectroscopy, and atomic force microscopy. The contact angle was found to be dependent on treatment conditions such as treatment time, agitation of pure water, dissolved oxygen concentration in pure water, and illumination. The contact angle of a water droplet on GaAs surface treated with agitated deionized pure water was found to increase with increasing treatment time, indicating that the hydrophobicity of the surface increased. The agitation of pure water strongly influenced the oxygen concentration and the roughness of the treated GaAs surface, and hence, the contact angle of a water droplet on it, t.


This paper is proposed the coupled line to discriminate the RF channel failure for active phased array. It is important to check the operational status of numerous channels in active phased array. The coupled line structure with slot was used to obtain the required signal level to check the channel status. The measured coupling level of coupled line shows about - 30 ~ -50 dB and it was enough level to check the channel failure of the radar system.


Externships or field placement programs involve students placed away from the law school and supervised by a person who is not employed by the law school. Externships offer many potential rewards for students as well as other stakeholders, including especially community institutions. But there are also risks—risks that the externship will be expected to accomplish too much with too few resources or that the externship program will be held back in the potential for contribution due to inadequate imagination or planning. This article seeks to encourage externship teachers to put aside assumptions that are sometimes made about how externship programs "should be" and consider some alternative approaches to course design and possible goals for externship courses.


ULTIMATE-Subaru (Ultra-wide Laser Tomographic Imager and MOS with AO Transcendent Exploration) is the next-generation development project of the Subaru Telescope in Hawaii, U.S.A. Ground Layer Adaptive Optics (GLAO) technology corrects atmospheric turbulence near the ground and improves the star image to realize wider fields of view (14 x 14 arcmin) than conventional adaptive optics can do. In the GLAO system, the laser launch system emits four lasers of up to 20 minutes of asterism, then these four lasers excite four artificial stars from 80km to 200km in the sky. The wavefront sensor (WFS) system observes them and corrects atmospheric turbulence. The WFS system also utilizes four natural stars outside the science field of view as well. This paper presents the preliminary optical design of the WFS system.


Purkrtova S., Babulikova J., Karpiskova R., Demnerova K., Pazlarova J. (2011): Antimicrobial factors effects on biofilm formation in Staphylococcus aureus. Czech J. Food Sci., 29 (Special Issue): S1–S10. We determined the disinfectant effects of benzalkonium chloride (BC) and Savo (SV), a chlorine compound, on the biofilm and planktonic cells in 23 strains S. aureus mainly food isolates. The biofilm formation was performed in a model system using microtiter polystyrene plates COSTAR 3797 in trypton-soy broth with 1% glucose at 30°C. Benzalkonium chloride (BC) at 125 mg/l, applied directly on 24 h old biofilm, was able to remove the biofilm matrix in 21 strains, and to stop the reproduction of the biofilm cells in 23 strains. BC at the concentration of 125 mg/l was lethal to planktonic cells, coincubated for 24 h or treated for 10 minutes. None of the strains studied was able to grow in SV at 1X recommended concentration, while the safety lethal concentration for planktonic cells treated for 10 min was 4X. The application of 4X concentration SV into the 24 h old suspension removed the biofilm matrix in all strains and devitalised the biofilm cells in 10 strains and inhibited the viability in 13 strains by 70%.


The Trid neighbourhood is a three cell neighbourhood on a 2dimensional lattice, and is a subset of the Quad neighbourhood. I show that, with an appropriately prepared initial configuration of "diagonal stripes", a given elementary CA can be simulated by the two state Trid neighbourhood CA whose local update rule is precisely that of the elementary CA. Thus, invoking Cook's universality result for elementary CA rule 110, I exhibit a universal two state Trid neighbourhood CA. 1. Definitions and notation The Trid neighbourhood on a 2-dimensional square lattice is defined by the neighbour offsets 〈(0, 1), (0, 0), (1, 0)〉 . (1) In other words, the neighbourhood of a given cell consists of the cell itself, and the cells immediately adjacent to the north and to the east. A Trid CA is a CA with two states (i.e. with state set Z2 = {0, 1}) using the Trid neighbourhood. A local update rule for a Trid CA is a function Z2 → Z2. An elementary cellular automaton (ECA) is a 1-dimensional CA with two states and the three cell neighbourhood 〈−1, 0, 1〉 . (2) Thus a local update rule for an ECA is also a function Z2 → Z2. A configuration of a CA is a mapping of a state to each cell in the lattice. Thus for a D-dimensional two state CA, a configuration is a function Z → Z2. The global map for a CA is the extension of its local update rule to a function from configurations to configurations, in the usual way. 2. Simulating ECAs with Trid CAs First, define a mapping α from 1-D configurations to 2-D configurations. Let s : Z→ Z2 be a 1-D configuration. Then the 2-D configuration α(s) is defined by α(s)[x, y] = s[x− y] for all x, y ∈ Z . (3) Intuitively, α(s) is obtained by mapping the cell states of s along the diagonals which run southwest to northeast. This has the effect that the Trid neighbourhood can "see" the states of three adjacent ECA cells, as depicted in Figure 1. The mapping α is injective, but not surjective; thus α does not have an inverse. However, define a mapping β from 2-D configurations to 1-D configurations by β(s2)[x] = s2[x, 0] for all x ∈ Z (4) for all 2-D configurations s2 : Z → Z2. Then it is easy to see that β ◦ α is the identity on the set of 1-D configurations. Furthermore, α ◦ β is the identity on


The per turbed an gu lar cor re la tion method was em ployed to study the tem per a ture de pend ence of elec tric field gra di ents at the 181 Ta probe in the polycrystalline Hf 2 Ni 7 com pound. The tem per - a ture evo lu tion of the sam ple con tent was mea sured us ing high-tem per a ture X-ray dif frac tion. To check the mag netic or der of the sam ple, mag ne ti za tion mea sure ments and ad di tional per turbed an gu lar cor re la tion mea sure ments with ex ter nally ap plied mag netic field were per formed. All ob tained spec tra showed no ev i dence of mag netic or der of the Hf 2 Ni 7 phase. Within the ex per i men - tal res o lu tion of the ap pa ra tus, the mea sured elec tric field gra di ents at 181 Ta probe for the two inequivalent 181 Hf / 181 Ta sites in the Hf 2 Ni 7 com pound ap peared as one in the range of 78-944 K. A sin gle quadrupole in ter ac tion im plies that the elec tric field gra di ents at the two Hf sites must be quite sim i lar. At 293 K, the mea sured quadrupole in ter ac tion pa ram e ters are n Q = 433(1) MHz and h = 0.300(4). An in crease of the quadrupole fre quency and a grad ual ris ing of the asym me try pa ram e ter were ob served with in creas ing tem per a ture. The high-tem per a ture X-ray dif frac tion in di cated a build up of HfO 2 above 693 K.


This research interrogates the current entrance audition requirements for select faculties of music in Ontario, Canada. This article engages with a literature review for the purpose of investigating and articulating the foundations of white supremacy and Eurocentric elitism of Western classical music as the gatekeeper for entrance into schools of music. Utilizing critical policy analysis and latent content analysis on the data gathered from university websites, this research aims to address the following questions: In what ways do post-secondary faculties of music uphold Eurocentric elitism of Western classical music and maintain white supremacy? What populations do faculty of music entrance audition requirements serve and invite? Whom do these audition requirements exclude? The findings of this research highlight the issues with current entrance audition requirements and suggests further reflection on the issues found in an effort to disrupt exclusionary structures.


In the cases where the results obtained by both methods were pathological, on 19 occasions the MC findings gave quite sufficient information, even about the upper urinary tract, whereas in only 9 cases did the urography reveal facts of interest beyond the MC findings. When the changes in toto are situated proximal to the vesicoureteral junction, no ureteral reflux is possible and in these cases the urography is of course the only method of demonstrating the site of the changes; but of 59 pathological cases only 6 belonged to this group. The MC is also superior to the passive, retrograde urethrography. Urography was superior to the MCfindings in 15 cases of 79. Both methods were of equal importance in 30 cases of 79. The MC findings were superior to the urography, in which the findings were insufficient in 34 cases of 53. To summarize the results, i t can be stated that MC is a very valuable urological roentgenological examination in childhood. The main indications are a) urinary infections of long standing or of recurrent type, b) when residual urine is found, c) in micturition disorders, d) in cases with congenital malformation of the lumbosacral spine or of the external genitals and e) in cases with enuresis of long standing. Owing to the radiation hazards to the gonads the MC may be carried out on indications other than those here mentioned only after special consideration.


Background and Objective: Substance abuse is a chronic recurring disorder who needs to manage therapy over time. The goal of current study was to assess the cognitive emotion regulation strategies and emotional schemas in men with substance abuse, abstinent and normal individuals. Materials and Methods : In the form of a causal-comparative design, using available sampling method 30 men with substance abuse, 30 abstinent and 30 normal individuals were selected and after matching on the base of age, education and the substance they used were assessed via cognitive emotion regulation questionnaire and emotional schemas questionnaire. Multivariate analysis of variance was used to compare the three groups. Results : In self-blame (P=0.0004) and catastrophizing (P=0.0008) maladaptive cognitive emotion regulation strategies, the scores of individuals with substance abuse were higher than abstinent and normal individuals and in rumination (P=0.0007) individuals with substance abuse and abstinent obtained higher score in comparison with normal individuals. In refocusing on planning (P=0.0005) and positive reappraisal (P=0.00) adaptive strategies, normal individuals and abstinent in comparison with individuals with substance abuse obtained higher scores. In mental rumination (P=0.0008), blame (P=0.0008) and simplistic view of emotions (P=0.0009) individuals with substance abuse, abstinent had higher scores in comparison with normal individuals. In guilt (P=0.008) and uncontrolled (P=0.006) emotional schemas, individuals with substance abuse in comparison with normal individuals obtained higher scores. Conclusion : No effective emotional schemas and emotion regulation strategies can play a key role in substance abuse initiation, maintenance and relapse.


This study aims to determine whether direct and indirect effects of organizational culture, principal leadership, and motivation on teacher performance at Madrasah Aliyah Irsyadul Islamiyah. The type of research used is a quantitative research using multiple linear regression formulas and flow analysis as its development. This study found that: 1) there was a significant influence between teacher motivation and teacher performance of 0.570. The contribution given by teacher motivation to teacher performance is 31.2%; 2) The influence of organizational culture and principal's leadership on teacher performance is 0.642. The contribution given by the head of madrasa communication to teacher performance is 41.2%; 3) Teacher motivation, organizational culture, and principal leadership together on teacher performance have a strong relationship of 0.737. The contribution of the two independent variables to the teacher's performance at Madrasah Aliyah Irsyadul Islamiyah was 54.3%, while the remaining 45.7% was the contribution of other variables not measured in this study.


Objective:To establish a cell model of skin fibroblast with high expression of matrix metalloproteinase 9(MMP9) for studying its roles in wound healing of diabetes foots.Methods: Different concentrations of sugar and homocysteine were uesd to cultured skin fibroblasts.The expression levels of MMP9 mRNA and protein,and the activity of MMP9 protein were detected in each group.Results:(1) The expression level of MMP9 mRNA in high glucose + high homocysteine group(7.05±1.02) was significantly higher than those in the normal glucose group and high glucose group(respectively,P0.01).(2) The expression level of MMP9 protein in high glucose + high homocysteine group(206.9±33.6) pg/ml was significantly higher than those in the normal glucose group and high glucose group(respectively,P0.01).(3) The activity of MMP9 protein in high glucose + high homocysteine group(1.47±0.13) was significantly higher than those in the normal glucose group and high glucose group(respectively,P0.01).Conclusion: The cell model of skin fibroblast with high expression of MMP9 was successfully established in vitro by high glucose + high homocysteine co-culture.


For the purpose of efficient treatment of heat-resistant alloys, an abrasive electrochemical part grinding method is proposed using an advanced abrasive wheel cleaning method by means of abrasive wheel contamination assessment. The process was researched and it was revealed that a parameter which is a ratio of cutting force against the ECT (electrochemical treatment) phase duration within one round of spindle revolution is versatile, which means it does not dependent on the EDM electrode cutting feed rate, the depth of treatment, and is an independent value.


Paragonimiasis is a chronic infection caused by a trematode of the genus Paragonimus, the Paragonimus westermani being the one that most infects man. It is an endemic disease in East Asia, however, it is also seen in America. The authors report two cases of paragonimiasis, in which a patient showed a past history and clinical and radiological characteristics suggestive of this disease, diagnosed by the presence of eggs of P. westermani in the sputum, and another patient, a thoracic post-traumatism empyema whose paragonimiasis diagnosis was a histopathological finding in the pleura after a decortication. This diagnosis was confirmed by the presence of eggs of P. westermani in the sputum.


Fluorescent concentrators concentrate both diffuse and direct radiation without requiring tracking of the sun. In fluorescent concentrators, luminescent materials embedded in a transparent matrix absorb sunlight and emit radiation with a different wavelength. Total internal reflection traps the emitted light and guides it to solar cells attached to the concentrator's edges. The escape cone of total internal reflection, however, limits the light collection efficiency. Spectrally selective photonic structures, which transmit light in the absorption range of the luminescent material and reflect the emitted light, reduce these losses. In this paper, we review different realizations of such structures and show that they increase collection efficiency by 20%. However, light emitted into steep angles in respect to the front surface, which would be lost without the photonic structures, has a very long effective path inside the concentrator until it reaches a solar cell. Therefore it suffers from path length dependent losses. We discuss how emission into the unfavorable directions can be suppressed by integrating the luminescent material into photonic structures, thus reducing these losses. We present possible realizations both for the concentrator design and for the solar cells used in such systems.


The definition of the term "intercultural education" is given in the article. The question of learning culture in the context of foreign language teaching is being under examination. The components of learning culture are described in detail. Special attention is paid to the problem of testing the cultural knowledge of students.


A finite element model is created using OpenSees software to perform a time history analysis in order to analyze the seismic response law of a skew bridge and the damage volume of its key components, using a typical 3×20 m skew continuous girder bridge as an example. The seismic response of the skew continuous girder bridge under various factors such as the size of the abutment expansion joint, shear key gap, and shear key strength is studied then the damage rate is assessed for the bearing, shear key, and pier. The research results show that under the action of earthquake ground motion with 0.3 g PGA, the seismic force transmitted to the pier is small, and the pier is elastic owing to the sliding of the bearing, but the damage degree of the shear key is larger than that of the bearing and pier. The impact increases the rotation effect of the main beam in the direction of off acute angle, resulting in a greater damage to the shear key at the acute angle than that at the obtuse angle. The damage of bearing and shear key increases and then decreases with the increasing of expansion joint, and the larger the skew angle is, the smaller the expansion joint will be corresponding to the maximum displacement of bearing and shear key. With the increase of the shear key gap, the deformation limitation effect of the shear key on the main beam decreases significantly, resulting in a linear increase in the bearing slip, which increases the risk of the main beam subsidence. With the increase of the shear key strength, the bearing and shear key damage decreases greatly at first, and then increases slightly. However, the pier damage increases obviously. In an area with a high risk of earthquake, it is recommended that the shear key can be a "fuse element". For any oblique angle, the shear key gap can be reduced to 2 cm, and the shear key strength can be increased to 125 % or 150 %. When the skew angle is between 30 and 60, the expansion joint size can be increased to 12 cm or 16 cm.


The paper describes the incorporation of statistical knowledge into two different Rule-Based MT (RBMT) systems. In earlier experiments, these systems were linked with Memory-Base MT components, so that by now the translation process is supported by three MT paradigms. The paper concentrates on the acquisition of rich, informative, balanced, and up-to-date statistical data from monolingual and parallel corpora and on ways of using these data in RBMT systems. The authors keep their pledge of a systematic investigation of the linkage of different MT paradigms aimed at improving the quality of translation.


I dentification of patients at significant risk of arrhythmia and sudden cardiac death is one of today's major cardiol-ogy challenges. Although tremendous progress has been made in detecting and characterizing cardiac disease and its progression, largely through imaging modalities, progress in detecting and monitoring changes in arrhythmogenic states has been incremental and has not resulted in robust, reliable methods of assessment. In this issue of Circulation , Ghosh et al 1 demonstrate the application of an evolving technology, electrocardiographic imaging (ECGI), for noninvasive assessment of cardiac electrophysiology. They provide convincing data documenting the success of the method for localizing preexcitation (accessory) pathways in Wolff-Parkinson-White patients as well as for assessing short-term remodeling of ventricular repolarization after pathway ablation. The method requires detailed, high-resolution 3-dimensional computed tomographic imaging of the patient's torso, body surface potential mapping of the torso with the use of hundreds of leads during any rhythms and conditions of interest, and mathematical modeling of the 3-dimensional electric fields to yield "inverse" estimates of epicardial potential distributions and electrograms. Once the 1-time anatomic imaging and modeling are completed (presumed constant for each patient), the body surface potential mapping recorded during any rhythm or cardiac condition can be transformed to the level of the epicardium to visualize epicardial isopotential map sequences, electrograms, and consequently activation and repolarization sequences.


A 73 year-old man was admitted to our hospital because of septic shock. He had undergone drug eluting stent (DES) insertion 40 days before this admission. After about 50 days in the hospital, a coccyx sore required a flap operation. The anticoagulation therapy (aspirin and clopidogrel) was then changed to LMWH. Eleven days after this change, he developed very severe chest pain. The emergency coronary angiography showed occlusion of the left anterior descending artery, left circumflex artery, and right coronary artery due to thrombosis. During the angiography procedure, his heart collapsed. We performed cardio-pulmonary resuscitation (CPR), but were unsuccessful. Patients in very high risk groups need special attention during peri-operative periods. Doctors must have full knowledge about the different anticoagulation strategies, and cooperation among the different clinical departments is needed to properly treat these high risk patients. (Anesth Pain Med 2010; 5: 227 ∼ 230)


The key points which this research will discuss can be divided into three parts. The first part is the symbol tactics of " Niceguy subculture" , next is the unique narration script of "Niceguy subculture" and the last is gender stereotype, social meaning that revealed in the discourse in" Niceguy subculture", the third part will discuss more deep social meaning and thinking. This research will integrate theories of culture into Internet studying, focusing on the resisting and impeding toward sex ideology. Research result indicate that "Niceguy subculture" tend to packing unhappy experience through the way of "kuso", or using some special narration structure to describe the mental state in one-sided love.They producing strongly optimistic mind by the humorous style, making readers not only feel lovely , laughable or warm while they reading these story but still can discover some deeper social effects. Next, "Niceguy subculture" is symbolizing the awakening of male sex consciousness. This research shows that the paternal society represents the phenomenon of misogyny, causing the constriction of fragile mood from male, making them seeking group cohesiveness which have similar experience by enter anonymous cyberspace and revealing themselves in the form of various kinds of discourse. Therefore, "Niceguy subculture" brings a lot of concept which people have never thought, or unwilling to think deeply. Finally, "Niceguy subculture" reflected the unbalanced situation between two sexes, in other words, compared to female makings stride into the categories of male's makings , male making stride into the female making will attract more unusual eyes in the mainstream society. That is because male itself is concerned to vested interests by society, resulted in the category of making man stride into women's makings is comparatively negative, therefore, although the gender stereotype becomes flexible nowadays, it still unable to dispel from the society completely.


Background: Lung is a radiosensitive organ. Studies have shown that exposure of the lung to acute and high doses of radiation following inhalation of radioactive agents or an accidental radiological event may lead to pneumonitis and fibrosis, which are associated with a risk of death. So far, some agents have been studied for mitigation of pneumonitis and fibrosis following exposure of murine lung tissues to ionizing radiation. In this study, we aimed to detect the possible mitigatory effect of alpha-lipoic acid, resveratrol and their combination on mice pneumonitis and fibrosis markers following irradiation. Methods: 25 mice were divided into 5 groups: control, radiation; radiation plus alpha-lipoic acid; radiation plus resveratrol; and radiation plus both resveratrol and alpha-lipoic acid. Mice chest regions were irradiated with 18 Gy using a cobalt-60 gamma rays source. Treatments started 24 h after irradiation and continued for two weeks. After 100 days, all mice were sacrificed and their lung tissues removed for histopathological evaluation. Results: Pathological study showed that exposure to radiation led to severe pneumonitis and moderate fibrosis after 100 days. Both resveratrol and alpha-lipoic acid, as well as their combination could mitigate pneumonitis and fibrosis markers. Although, resveratrol could not mitigate infiltration of most inflammatory cells as well as inflammation and vascular damage, alpha-lipoic acid and its combination were able to mitigate most damaged markers. Conclusion: Alpha-lipoic acid and its combination with resveratrol were able to mitigate fibrosis and pneumonitis markers in mice lung tissues following lung irradiation. Although resveratrol has a protective effect on some markers, it has a weaker effect on lung injury. In conclusion, our results suggest that the combination of resveratrol and alpha-lipoic acid has a potent mitigatory effect compared to the single forms of these agents.


Abstract To further improve the strength and toughness, the advanced thermomechanical controlled processing has been applied in the development of an ultralow C and high Nb bearing steel. In the present investigation, the effects of processing parameters, consisting of the coiling and starting temperatures in non-recrystallisation region, on the final microstructure and mechanical properties of this steel have been studied by tensile, Charpy impact tests, optical microscopy and transmission electron microscopy. Results indicate that the acicular ferrite dominated microstructure can be greatly refined in grain size with decreasing the starting temperature of finishing rolling. However, for high Nb steels, the too low starting temperature would promote the formation of high temperature transformation products and consequently make against the improvement of mechanical properties. In addition, the optimum temperature window of finishing rolling is found to be also related to alloying levels of austenite stabilising elements. At the high starting temperature of finishing rolling, the precipitation strength contribution increases with increasing coiling temperature. However, the increase in strain accumulation associated with low temperature processing greatly reduces the sensitivity of the precipitation strength contribution to coiling temperature.


Gaze behavior is one of the most important nonverbal behaviors during human-human close encounters. For this reason, many researchers in natural human-robot interaction focus on developing robots that can achieve human-like gaze behavior. Many approaches have been proposed to achieve this natural gaze behavior based on accurate analysis of human behaviors during natural interactions. One limitation of most available approaches is that the behavior is hardwired to the robot and learning techniques are used only, if ever, for adjusting the parameters of the behavior.
 In this paper we propose and evaluate a different approach in which the robot learns natural gaze behavior by watching natural interactions between humans. The proposed approach uses the LiEICA architecture developed by the authors and is completely unsupervised which leads to grounded behavior. We compare the resulting gaze controller with a state-of-the-art gaze controller that achieved human-like behavior and show that the proposed approach leads to a more natural gaze behavior based on subjective evaluations of subjects.


We need to describe our algorithm and prove it has the above properties. We are allowed to use the number-theoretic facts stated in the tutorial sheet without proof. The algorithm we will devise is very simple. This algorithm and the proof that it works are due to Arnold Schönhage ([4], 1979). For any positive integer m, let [m] = {1, . . . ,m}. We are given circuit C1 consisting of gates g0, . . . , gn1 , and circuit C2 consisting of gates g′ 0, . . . , g ′ n2 , and hence where C1 and C2 have sizes n1 and n2, respectively. Let n = n1 + n2. We can assume without loss of generality that n = n1 + n2 ≥ 7, because otherwise, if n ≤ 6, we can easily (deterministically) compute the values val(C1) and val(C2) by evaluating both circuits in constant time, and then check whether or not val(C1) is equal to val(C2). Our randomized algorithm, parametrized by a positive integer k (which is the number of repetitions we will use to amplify the success probability to a "sufficiently high" level, to be determined later), is as follows:


Background: People experiencing or perceived to have a mental illness often subject to stigma from many sources which can be automatically internalized and result in internalized stigma. Aim: This study aimedat assessing the levels of internalized stigma and explores relation between demographic, clinical data, and internalized stigma among psychiatric inpatients in Minia governorate. Research Design: A descriptive correlational research design was used in this study. Study subjects and setting: 50 psychiatric inpatients at Minia Hospital for Mental Health and Addiction Treatment in New Minia City were included in the study. Tools: Socio-demographic and clinical data questionnaire and Internalized Stigma of Mental Illness Scale were used. Results: More than half (60%) of the studied patients were males, near to one third (30%) had schizophrenia, less than two thirds (60%) of them had a moderate level of internalized stigma, while 26% of them had high level of internalized stigma and only 14% of them had low level of internalized stigma. Conclusion: There were no statistically significant differences between internalized stigma levels and all sociodemographic and clinical data of the patients except for occupation and duration of hospitalization. Recommendations: Designing and implementing psycho-educational programs for psychiatric mentally ill patients to decrease internalized stigma are needed.


Critical Care Medicine • Volume 46 • Number 1 (Supplement) www.ccmjournal.org Learning Objectives: Sulfamethoxazole-trimethoprim (SMXTMP) is a commonly prescribed antibiotic regimen. Rarely, this regimen has been associated with hepatotoxicity. Methods: We report the case of a 25 year old female with no significant medical history who was prescribed SMX-TMP for the treatment of an infected soft tissue injury. Over the next seven days, patient developed fever, chills, and malaise which progressed to nausea, vomiting, and rash to her abdomen and face. On hospital presentation, serum acetaminophen and ethanol concentrations were undetectable, and urine toxicology panel was negative. Tomography revealed marked gallbladder wall edema, parenchymal edema, and perihepatic stranding suggestive of acute hepatitis. By the third day of hospital admission patient had developed alkaline phosphatase 308 unit/L, aspartate aminotransferase 17820 unit/L, alanine aminotransferase 8261 unit/L, total bilirubin 3 mg/dL, partial thromboplastin time 85 s, and international normalized ratio > 12. Hepatic injury was without evidence of cholestatic pattern. Serum differential revealed zero eosinophils. All microbiology cultures and serology for cytomegalovirus, herpes simplex virus, and hepatitis A, B, C were negative. Disease progressed to fulminant hepatic failure. Treatment beyond supportive care included N-acetylcysteine and systemic corticosteroids. Patient developed acute kidney injury and received continuous renal replacement therapy. Hemodynamic instability required substantial vasopressor support. After apparent acute hemorrhage on the fifth day of hospitalization, laparotomy, complete hepatectomy, and portacaval shunt were attempted but patient did not survive the procedure. Liver pathology revealed massive hepatocellular necrosis with portal tract inflammation and abundant eosinophils. Results: Few cases have reported hepatic injury associated with SMX-TMP. Hepatotoxicity via SMX-TMP is usually associated with cholestatic reaction. This case uniquely describes the fast progression of fatal, fulminant hepatic failure mediated by hepatocellular necrosis. Additionally, serum differential included zero eosinophils while hepatic pathology ultimately revealed presence of eosinophils in portal infiltrates.


17.3 per cent of its expenditures to auto transportation.12 The average expenditure for the purchase and operation of a car in these families was $757 per year. Since this figure is an average for all households, including ones which did not own cars, the actual expenditures of the car-owning families probably substantially exceeded $750. These large outlays for auto expenses interfere both with the accumulation of the household goods needed by


The Backus-Gilbert Inversion technique is a proven method of temperature inversion in microwave radiometry with a scope of trade-off between desired resolution and tolerable noise. In this study it is used to super-resolve brightness temperature data independent of the inversion process. The BGI-method is applied on scan-mode TMI (TRMM Microwave Imager) data. The 19.35GHz TMI channel provides brightness temperature data oversampled by a factor of two and geo-collocated with the 37GHz channel data. Consequently, the enhancement of features in the 19.35GHz image after BG-resolving is validated by the identification of such features in the 37GHz image. The potential of the BGImethod as a non-degrading interpolation technique is also tested.


News application is an application used to read news from one or more sources. The development of this Android news application is based on the use of smartphones and tablets which are starting to become a necessity in today's society. The application is made so that readers can access news wherever and whenever as long as internet connection is available. News source used by the application is Dwi Pekan Petra Christian University. Until now, Dwi Pekan publishes their news in the form of print media and via the website. To maximize Dwi Pekan publication, an Android application is made so that Dwi Pekan can better reach its readers. In the application there are several features that can simplify Dwi Pekan readers in getting the best reading comfort. Dwi Pekan application provides news to be able to meet the reading needs in different types and sizes of smartphones and tablets. The application was created using Ionic Framework with JavaScript Framework AngularJS, Cordova API, and Node.js. After going through the process of testing that has been done, the application can show Dwi Pekan news and present it well. Applications can also run all the features contained in it.


Clustering is an AI technique that has been successfully applied to the abundance of unlabelled real-world data for revealing hidden patterns and knowledge extraction. Deep Embedded Clustering (DEC) is a deep Autoencoder (AE) based model that learns feature representations and cluster assignments simultaneously. DEC learns the mapping from input data to a low-dimensional embedded space through joint optimization of feature transformation and clustering. Our previous work demonstrates how adding residual connections to deep AEs (RAEs) reduces the performance degradation of learned features when performing downstream classification on learned features. Further, it evidenced that RAE has improved unsupervised feature learning capability compared to AE. In this paper, we are evaluating the effect of residual connections in the context of Deep Embedded Clustering (DEC), which we refer to as RDEC. RDEC was compared against regular DEC. We considered various numbers of hidden layers and several bench-mark datasets: MNIST, Fashion MNIST, Reuters, and Human activity recognition. When increasing the depth of the neural network gradually, the presented RDEC showed up to 56% of less performance degradation compared to DEC. Further, the distribution of clustering accuracies showed that the presented RDEC outperforms DEC when comparing the accuracy variance and mean accuracy.


The photosensitivity of glasses can be significantly enhanced by high-pressure low-temperature hydrogen loading prior to UV exposure. The chemical reactions that occur between hydrogen and glass under UV exposure are thus of primary importance for the understanding of the mechanisms of H2 photosensitivity enhancement.


The EPR-spectral zero-field splitting parameter D of the localized heterovinyl-substituted 1,3-cyclopentanediyl triplet diradicals T, generated in a 2-methyltetrahydrofuran (MTHF) glass matrix at 77 K through the photochemical deazetation of the corresponding azoalkanes 1-13, is a quantitative measure of the spin-density (rho) variation by the substituents at the radical site in the 1-heteroallylic radicals. From these data, the radical-stabilizing ability of a variety of nitrogen-containing groups has been assessed, which includes imino and hydrazonyl functionalities. The radical stabilization in the heteroallylic radical fragment follows the order X = O < NMe < CH2 < CHMe << NOH approximately NOMe << NNHCHO approximately NNHC(O)NH2 < NPh approximately NNMe2 < NNH2 < CHPh < NNHPh. The lowest D values have been found for the hydrazonyl-substituted derivatives, which implies the lowest spin density at the carbon center and, thus, the most efficacious radical stabilization through spin delocalization. This superdelocalization may be rationalized in terms of nitrogen-centered radical-cationic structures. Localization of the spin at the terminal atom is resisted through the electronegativity effect (O < N < C).


Embryonic development and larvae of Eviotu abm and E. storthynx are described. Eggs are fusiform in both species, measuring 1.16-1.19 ~059~0.63 mm in E. abax and 1.19-1.31 x0.370.42 mm in E. storthynx. Numerous minute processes cover the surface of the eggs of both species, Total length of newly hatched larvae is 2.6-2.8 mm in E. abm and 1.9-2.1 mm in E. stovthynx. Cuplae and red pigments are observed in larvae of both species. Larvae of E. abax, reared for 16 days after hatching, grew to 4.3-4.5 mm in total length. In these larvae, as they grew, the number of melanophores decreased and the red pigments, which are marked features in the embryo, disappeared.


As planning and autonomy in general become increasingly deployed on board spacecraft, missions will face a paradigm shift in how ground operations teams command and interact with the spacecraft: moving from specifying timed sequences of commands to high-level goals that on-board autonomy will elaborate based on the spacecraft's state and sensed environment. It will become increasingly difficult for operators to predict a mission's outcome as autonomous spacecraft venture into deeper space, react to unknown conditions, and face stronger communication constraints. However, data from simulated autonomous missions can be analyzed and lever-aged, allowing operators to make informed decisions when selecting mission parameters and high-level goals. To this end, our paper presents a framework that gains insights from simulation data in order to help operators of autonomous spacecraft missions to predict, explain, and search for specific outcomes given a set of high-level goals. We show and discuss how our approach can help operators to better understand predictions, explore options and make informed decisions. Specifically, we describe a case study that builds upon previous work on simulated autonomous spacecraft missions to the Neptune-Triton system where the spacecraft uses an automated planning and execution framework to make onboard decisions (Castano et al. 2022; Vaquero et al. 2022).


The ability to speak English or speaking skills is one aspect of learning a language. There are various things that can be done to develop students' speaking skills, one of which is visiting foreigners conducted by SMK N 1 Banyudono in the English Conversation Club extracurricular activities. This is done so that students get a provision for communication in English so that when students graduate from school as graduates of vocational school students have provision of communication skills both in the native language and English as a foreign language. After this activity is carried out, a follow-up activity will be held, where students make reports and presentations about the conversations they have had so that students can evaluate the activities that have been carried out. Furthermore, this activity is considered quite important and must be continued in addition to developing speaking skills, this activity can also develop students' confidence.


The mining of successive examples is a central part in numerous information mining undertakings. A lot of examination on this issue has prompted a wide arrangement of efficient and scalable algorithms for mining frequent patterns. On the other hand, discharging these examples is posturing worries on the protection of the clients' participating in the data. In this proposition, we examine the mining of successive examples in a protection saving setting. We propose an approach for differential private frequent itemset mining which is based on LCM algorithm; we refer it as P-LCM algorithm. P-LCM is extended version on PFP growth algorithm which basically has two phases such as preprocessing and mining phase. The preprocessing phase needs to be performed only once and smart splitting method is used in this phase for improving utility as well as privacy trade off. Second phase limits the information loss caused by splitting as well as reduces the amount of noise added during mining process. In addition we propose three algorithms LCMfreq for mining all frequent sets instead of PFP-growth. LCM finds all frequent item sets in polynomial time per item set, and at the same time doesn't store prior obtained closed item sets in memory. The computational experiments on real world and synthetic databases suggest on comparing their performance to the previous algorithms, that LCM algorithms are faster on large real dataset especially in case of high degree of privacy, high utility and high time efficiency.


ABSTRACT Zinc finger transcription factors, STOP1-like proteins, are conserved among land plant species and control the expression of aluminum tolerance genes in various plant species. We performed transcriptome analyses in tobacco (Nicotiana tabacum) to identify NtSTOP1-regulating Al tolerance genes, the expression of which was regulated by their STOP1-like proteins, and then compared them with those in Arabidopsis (Arabidopsis thaliana) and rice (Oryza sativa). A commercially available oligo microarray identified 96 genes in a NtSTOP1-RNAi tobacco line that showed lower expression levels than in the wild type under Al stress. It was shown that most NtSTOP1 controlled genes were common to both Arabidopsis and rice, although some were missing in Arabidopsis, which is more sensitive to Al than tobacco and rice. For example, NtSTOP1 regulated the expression of orthologs of rice STAR1, the expression of which was regulated by the STOP1-like protein ART1 in rice, but not in Arabidopsis. The NtSTOP1-RNAi line showed lower expression levels of genes involved in N-metabolism, including additional genes which were not regulated by STOP1 in Arabidopsis. In addition, NtSTOP1 controlled the expression of several genes for enzymes of fermentation pathways, although it was not identified in Arabidopsis. We also revealed the NtSTOP1 binding site containing the GGNVS motif of the NtMATE promoter. The motif that causes STOP1/NtSTOP1 to bind to AtALMT1/NtMATE, respectively, was similar, but AtALMT1 and NtMATE are fundamentally different genes. This difference in the STOP1-regulating system between tobacco and Arabidopsis is linked to differences in mutations in cis-elements in several target genes.


The efficacy of synthetic Zn-Al-SO4 LDH (layered double hydroxide) in removing aqueous molybdate was tested through batch sorption experiments. Up to 54% Mo was removed; the most efficient mechanism was sulphate-molybdate exchange within the LDH interlayer. The Mo uptake was influenced by the Zn/Al molar ratio: higher ratios (Zn/Al = 3) facilitated the release of sulphate from the interlayer and the entrance of molybdate, while for lower ratios (Zn/Al = 2 and 1.7) surface adsorption of molybdate became an important uptake mechanism. The Mo removing potential shown by Zn-Al-SO4 LDH may prove useful for the treatment of moderately contaminated waters from metallurgical and mining activities.


Based on the internal transcribed spacer(ITS) sequence difference between Oidium neolycopersici and other tomato fungal pathogens,two primer pairs(OidF1/R1,OidF2/R2) were designed to detect the fungal pathogen,tomato powdery mildew.For both pairs,specific bands around 350 bp were amplified respectively using genomic DNA extracted from O.neolycopersici,inoculated tomato leaf while no PCR product was amplified with DNA from other fungi inoculaterd and noninoculated tomato leaves.As low as 1 ng of O.neolycopersici genomic DNA can be detected by both specific primer pairs.This protocol provides a rapid,reliable and sensitive tool for detection and identification of O.neolycopersici.


Objective: To demonstrate the effects of rheumatoid arthritis (RA) on hearing with audiometric and tympanometric measurements, and to reveal its relationship with the disease in comparison with healthy volunteers. Methods: The study included 30 RA patients and 30 healthy controls. Demographic findings such as age, height, weight, onset of complaint (year), time elapsed since diagnosis, previous surgery, accompanying systemic disease, drugs used, family history, habits of smoking and alcohol use were questioned for both groups. Tympanometry, pure voice audiometry and otoacoustic Emission tests were performed. Results: The hearing thresholds in the airway conduction in RA group were significantly higher in all frequencies (0.25-6 kHz) than in the control group. When bone conduction hearing thresholds were compared, RA group was more affected at only 4 kHz and left ear (p=0.006). When air-bone conduction differences (AB-gap) were examined, the differences in the RA group at 0.5, 1 and 4 kHz were statistically significant. When tympanometry and acoustic reflex measurement results were evaluated, there was no statistically significant difference between groups. In the transient OAE test, 3 (10 %) patients were in the RA and 2 (6.6 %) patients in the control group (p=0.064). Conclusion: Conductive hearing loss was significantly more frequent in patients with RA than in healthy individuals, whereas bone conduction was affected partially at high frequencies; whereas stapes reflex, compliance and pressure values were not significantly affected.


In 1962 Dr. Maggio published "Micro-emacro-circulazione," 11 Pensiero Scientifico Editore, Roma. The present volume is stated in the preface to be an abbreviated and compressed version of the Italian text published for the English-reading public. One consequence of this transformation has been that the text is a little indigestible, in parts reading more like a review of the literature than an authoritative monograph; some 600 references are mentioned frequently in about 120 pages of text. The book starts with a historical survey of earlier work and methods in the study of the physiology of small arteries, veins, and capillary circulation. Some mention is made of newer techniques, e.g. television micro-spectophotometry and isotope clearance methods, but their use is not described in sufficientdetail for one to make any assessment of their real advantage.


A solution to the conservation of the small-scale landscape of Twente (the Netherlands) is found in the production of regional products, such as buckwheat and elderberry. Especially when agricultural production is started using organic production methods satisfactory financial results are expected


The cropping systems of(cucumber) and other different crops which were conducted in plastic greenhouse on(Loess) Plateau were studied.The results show that after cucumber harvest,there is(significant) effects of different cropping systems on soil(microbe,) the soil microbe is the(lowest) in follow,the second lower is(planting) cowpea or other legumina(crops.) The highest cucumber yield can be got after(planting) corn for green manure,black-bean for green (manure) or(planting) cowpea,then higher(cucumber) yield can be got after follow,the cucumber(yield) is the lowest after planting(tomato,) cabbage.It is efficient rotation system for overcoming continuous cropping obstacle to use rotation system of (cucumber) with corn for green manure,black-bean for green manure or planting cowpea.


Following up the previous work, [1], a new approach to the problem of shear localization is proposed, based on energy minimization principles associated with micro‐structure developments. In this approach, two different material models are included. They represent the behaviour of material at very small strain and very large strain, respectively. Herein, shear bands are treated as the micro‐shearing of rank‐one laminates. The thickness of a shear band represented by its volume fraction is assumed to tend to zero while the strain inside the shear band tends to infinity. The existence of shear bands in the structure leads to an ill‐posed problem which can be solved by means of energy relaxation. The performance of the proposed energy relaxation is demonstrated through numerical simulation of a tension test under plane strain conditions. The presented numerical simulation shows that there is no mesh‐dependence. (© 2010 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim)


The sufficient and necessary condition of deadlock occuring in S3RP manufacturing system is presented based on the Petri netmodel.The minimal deadlock structure mamed siphons is analyzed.According to the P-invariant,the controlling strategy of avoiding deadlock is fully investigated.The effect of the described method is demonstrated using an example.


Engineering and medicine has been intertwined for a very long time and in the recent years the relationship has been getting stronger and more important to the advance of healthcare. Surgeons and engineers are collaborating are using 3-D models to plan complex procedures. To do that, engineers must speak a language surgeons can understand. This article looks at how Boston Children's Hospital has invested in the Cardiac Surgery Research department and wants engineers engaged "in the room where it happens." Then they can observe, study, and communicate with surgeons to truly understand their problems and the type of solutions that they would want to use.


Background: Seropositivity of Chlamydia trachomatis in men is suggestive of chronic and recurrent infection with this sexually transmitted organism. Most males with urogenital Chlamydia infection have serum immunoglobulin G (IgG) antibodies to C. trachomatis that persist for years. Serologic studies linking C. trachomatis to male infertility and sperm quality lead to highly variable results. The objective of the study was to examine the effect of Chlamydia infection, as determined by Chlamydia seropositivity on semen quality.Methods: One hundred men having semen analysis as part of infertility work up had anti-Chlamydia antibody test. They were grouped into those who are seropositive for Chlamydia antibody IgG and those who were not. The sperm parameters and prevalence of different semen abnormalities were compared between the two groups, Chlamydia positive and Chlamydia negative.Results: There are no significant difference in semen parameters and prevalence of different semen abnormalities between the two groups. The sonographical finding of epididymal cyst is 45.8% in Chlamydia positive compared to 12.2% in Chlamydia negative; the difference is significant.Conclusions: Seropositivity of Chlamydia infection in infertile male is not predictive of semen abnormalities. Serological screening of the male partner for Chlamydia trachomatis provides no more benefit than identifying the female partner at risk of tubal factor infertility and males at risk of epididymal obstruction.


The five-year-old Palestinian uprising, the intifada, was the first of many mass mobilizations against nondemocratic rule to appear in the Middle East, Eastern Europe, East Asia, and the former Soviet Union between 1987 and 1991. Although the Palestinian struggle against Israeli occupation of the West Bank and Gaza Strip is seldom included by the media or by social scientists in their treatments of this putative wave of "democratization," many studies of the uprising are available. Although largely atheoretic in their construction of the intifada and in their explanations for it, the two general questions posed by most of these authors are familiar to students of collective action and revolution. On the one hand, why did it take twenty years for the Palestinians to launch the uprising? On the other hand, how, in light of the individual costs of participation and the negligible impact of any one person's decision to participate, could it have occurred at all? The work under review provides broad support for recent trends in the analysis of revolution and collection action, while illustrating both the opportunities and the constraints associated with using monographic literature as a data base.


Numerical evaluation of statistics plays an important role in data assimilation and filtering. When one focuses on stochastic differential equations, Monte Carlo simulations or moment closure approximations are available to evaluate the statistics. The other approach is to solve the corresponding backward Kolmogorov equation. However, a basis expansion for the backward Kolmogorov equation leads to infinite systems of differential equations, and conventional numerical methods such as the Crank-Nicolson method are not available directly. Here, a local approximation of the Crank-Nicolson method is proposed. The local approximation transforms the implicit time integration algorithm into an explicit one, which enables us to employ combinatorics for the proposed algorithm. The proposed algorithm shows a second-order convergence. Furthermore, the convergence property naturally leads to extrapolation methods; they work well to calculate a more accurate value with small steps. The proposed method is demonstrated with the Ornstein-Uhlenbeck process and the noisy van der Pol system.


Abstract The essential oils from the epigeous (above ground) and hypogeous (below ground) parts of Meum athamanticum Jacq., which were obtained by hydro-distillation, were subjected to analysis by GC and GC/MS. The major components were found to be (E)-β-ocimene (34.9%), p-cymene (12.1%), (Z)-β-ocimene (10.2%) and δ-3-carene (6.2%) in the epigeous part oil and (Z)-ligustilide (36.2%), (E)-β-ocimene (14.4%) and (Z)-3-butylidene phthalide (6.3%) from the hypogeous part oil.


Process capability ultimately decides process quality level. Based on analyzing process capability index (PCI), Process capability may be effectively assured. For the multivariate manufacturing processes, tremendous difficulties are often encountered when one attempts to measure the process capability by directly extending the univariate approach. After analyzing the multivariate Cpm method (Chan et al. 1991), the paper presents a spatial multivariate PCI method, which can solve multivariate off-centered case and may provide references for assuring and improving process quality level while achieving overall evaluation of process quality. At last, examples for calculating multivariate PCI are given and the experimental results show that the systematic method presented is effective and actual.


Business professionals and researchers have made considerable efforts and significant technical breakthroughs in information security in the last decades. Nevertheless, companies and organizations continue to incur losses associated with security issues. In order to remedy to this situation, we propose a new approach to information security engineering for companies and organizations. First, this approach is based on the standards and good practices of security, second, is inspired from the best practices and feedback of advances in the engineering of enterprise information systems security, and third, its design takes advantage of more than twelve years of experience in system architecture and information security for reknown banks and financial institutions. Our approach to engineering of information systems security aims at: reducing losses relating to security issues in companies and organizations, operating on an enhanced and sustained information security; improving the reliability of processes in companies and organizations, and assisting companies in legal and regulatory compliance efforts, operating on security indicators and checkpoints at various levels of management; helping companies gain competitive advantages through their security management solutions, operating on a global security monitoring system with feedback. As further development of the basic principle of Security know-how Encapsulation into UML profiles [14], we have introduced the mapping global picture of the Process of Security engineering into the formalism of Business Processes. The purpose of this paper is to provide a clear methodology based on the elaboration of the key Security Acts of the process of information systems security engineering. The paper consists of three major parts: Part One recalls the reasons why BPM has been chosen for our process of system information security. Part Two develops the key security acts of the process of information systems security engineering. Part Three shows some security metrics to illustrate the aims of our works.


Objective To construct the gradient heat stress rat model and thus to study its influence on core body temperature(Tc) during heat stress and prognosis. Methods Male SPF SD rats were randomly divided into normal control group,41℃ group,the 42℃ group,43℃ group and 44℃ group. Except for normal control group,the rats were exposed 39℃ heat stress. The rectal thermocouple was used to measure rectal temperature as Tc,which was monitored every 10 min. When the corresponding preset temperatures were reached,the rats in the 41℃,42℃,43℃ and 44℃ groups were placed in ambient temperature of 25℃. The Tcwas monitored within 8 h,and the survival within 72 h was also recorded. Results With varying degrees of heat stress,the Tcof rats was presented in different patterns. Biphasic rise was observed in 41℃ and 42℃ groups,while triphasic rise was observed in 43℃ and 44℃ groups. Out of heat stress,the Tcin 41℃ and 42℃ groups was returned to normal levels within 1 h,while low Tcwas observed in 43℃ and 44℃ groups, and especially in 44℃ group. Deaths were recorded in 43℃ and 44℃ groups,while significantly worse prognosis was revealed in 44℃ group according to survival analysis(P 0. 01). Conclusion Different degrees of heat stress have significant effect on Tcin rats. The higher degree of heat stress,the lower Tcis presented during the convalescence,suggesting worse prognosis.


RESPECT THE INVENTION A PARTICLE FILTER COATED ACTIVE FOR THE SEPARATION OF GAS OR LIQUID, AND METHOD FOR PRODUCING. FILTER IS ONE CONTINUOUS FIBER FABRIC CONTAINING MATERIAL THEREIN ACTIVE PARTICLE, IN POWDER OR GRANULES AND ABLE TO ABSORB OR LINKING OR CHEMICALLY SET OF GAS LIQUIDS OR SPECIFIC COMPONENTS. THE FABRIC FIBER POROUS ENOUGH TO ALLOW DISTRIBUTION WITHIN SAID IN HIS CONSTITUENTS LIQUID OR GAS BUT ENOUGH TO KEEP UP COMPACT MATERIAL PARTICLE ON. CURRENT GAS AND LIQUIDS PURIFICATION PASS LAYERS THIN ALONG THE FABRIC FIBRE, SO THE CONSTITUENTS ARE eNTERING TO SEPARATE THE FILLER FABRIC OF FIBER TO FIX OR If ABSORB IN pARTICLE MATTER. APPLICATION PARTICULAR THE CLEANING THE AIR.


Since 2009, studies on geoengineering have been increasing in the international community with a rapid development momentum. Various research projects and research findings continue to emerge, which deserves special attention. By reviewing the latest literatures, conference speeches and other related source of information, this paper analyzes major contentious issues, summarizes the latest research trends and gives further insight into China's geoengineering research.


. Among completely regular locales, we characterize those that have the feature described in the title. They are, of course, localic analogues of what are called cl-isocompact spaces. They have been considered in T. Dube, I. Naidoo, C. N. Ncube (2014), so here we give new characterizations that do not appear in this reference.


Background and Aims:  In healthy adults and those with type 2 diabetes (T2DM), poor sleep quality has been associated with poor physical function and low levels of physical activity (PA). Little is known regarding the influence of race on these relationships. The aim of this study was to examine racial differences in the relationship between physical function, habitual activity, and sleep in adults with T2DM. Methods: We used a descriptive, correlational design. We used t-tests and correlation analyses. Objective habitual activity and sleep outcomes were measured and averaged across 5 days using wrist actigraphy (Actiwatch Score).  Sleep measures included wake after sleep onset (WASO), time to fall asleep (sleep latency), and sleep time. Physical function was assessed using the six-minute walk distance (6MWD) test.  Glucose control was measured using capillary blood for hemoglobin A1c (A1C). Results : A total of 89 (58 Black, 31 White, age 58.3 ± 8.9 years) completed the study.  Black subjects were younger (56.7 vs. 61.3) and poorer glucose control (A1C 8.2 vs. 7.1) than whites. Among the total group, habitual activity was associated with sleep latency (r=-0.45) and 6MWD was associated with habitual activity (r=0.381) and WASO (r=-0.288). All p<0.05.  In whites habitual activity was related to latency (r=-0.391), while 6MWD was related to WASO (r—0.409). In blacks, habitual activity was related to 6MWD (r=0.42) and sleep latency(r=-0.511), while 6MWD was related to sleep latency (r=-0.354). All p<0.05. Conclusions: In adults with T2DM, increased habitual physical activity is related to improved sleep, and physical function, but these relationships differ by race and sleep measure. Based off this study, physicians should include increasing daily activities as part of their prescription in order to improve sleep outcomes in patients with T2DM.


In a patient with severe, recurrent bilateral carpal tunnel syndrome secondary to mucolipidosis, the 'turnover' palmaris brevis flap was used in conjunction with internal neurolysis. The procedure was effective in alleviating symptoms of recurrent carpal tunnel compression in both hands.


This paper explores the effects of tax asymmetries on the value of risky capital investments made by corporations.The government's claim on the firm is shown to be equivalent to a portfolio of options on the firm's revenues. The tax law's provisions for carrying tax losses forward and backward are introduced, necessitating a numerical solution for the value ofthe government's claim. The results show that asymmetric taxation of operating gains and losses can significantly affect the after-tax net present value of corporate investment opportunities.


The technology to fabricate polycrystalline diamond film resistors has been initiated using modified thick film patterning techniques and in situ solid source doping. Doping of polycrystalline diamond films in microwave plasma CVD systems has been achieved historically through use of diborane gas, which may contaminate the deposition system causing all diamond films thereafter to be doped p-type. We have attempted noncontaminating in situ doping utilizing two solid source dopants, and have met with preliminary success. The more effective source (B 2 O 3 ) produces a fairly even dopant concentration across the substrate, with sheet resistances ranging from 800 ohms per square to 4500 ohms per square. The other source (BN) showed significant doping in a narrow band surrounding the source, but the doping concentration decreased rapidly with distance from the source. Films grown afterwards with no doping were evaluated through resistance measurements; no evidence of doping contamination was observed.


Global warming and climate change represent one of the greatest challenges for today's governments and organizations. The increased concentrations of greenhouse gases (GHGs) in the atmosphere, caus ...


A Human Action recognition system is proposed using the Skeletal Tracking from Kinect. The angular information of the joints helps in handling scaling errors. Vectors are generated using the joint coordinates and the angles of each joint are used as features for key pose recognition. A rotational compensation is included in the feature to handle rotational errors. The key poses are recognized using Similarity Matching Technique, neural network and decision tree algorithms. The recognized key postures are fed into a decision forest to pick the action based on the trained sequence of key poses.


The process of identification as an indispensable process of an individual's activity prior to his further actions is in its nature an initial form of exploring the world, for example in case of a contact with the environment in coming across an unfamiliar word. Peculiarities of word identification are being formulated on the basis of analysis of a wide range of published experimental researches. Dynamic, spontaneous, continuous character of identification enables us to view this process in terms of synergetics, namely as interaction of energy streams, coming from the person as a subject of cognitive processes, and the word as an environmental stimulus, its associative potential.


Contract, generally, is a binding agreement between two or more persons which creates mutual rights and duties and which are enforceable at law. Remedy will be available to the innocent parties if the other party fails to perform his part of agreement. For building contract, damages will be an adequate compensation for a breach due to majority of issues and disputes in building contract involves money. The parties nonetheless can choose to seek for specific performance. Specific performance is one of the equitable remedies where the court will ask the party to perform his part of a contract. However, the parties in a building contract do not favour this right in remedying the breach, and similarly there is not much law cases that illustrate the specific performance has been exercised especially in building contract. Hence, this master project has been done to identify the reason for not granting specific performance by the court with respect of building contract. The law cases collected from year 1980 to year 2009 is done mainly through documentary analysis of law journals and law reports via Lexis-Nexis website, e.g. Malayan Law Journal, Building Law Report, Construction Law Report, etc. The results show that there are 7 reasons in which the specific performance will not be granted to the parties in a building contract such as when there is adequacy of legal remedies, constant supervision from the court, uncertainty terms in a contract, on the ground of hardship, vacant possession of site, willingness and readiness as well as whether valid contract has exists or not. This research will shed some light in exposing what are the possible reasons that the court may refuse to grant specific performance and forms a guideline for the parties in a building contract when they resort to specific performance.


The single-particle inclusive differential cross-section for a reaction a + b → c + X is written as the imaginary part of a correlation function in a forward scattering amplitude for a + b → a + b in a modified effective theory. In this modified theory the interaction Hamiltoniañ H I equals H I in the original theory up to a certain time. Then there is a sign change and˜H I becomes nonlocal. This is worked out in detail for scalar field models and for QED plus the abelian gluon model. A suitable path integral for direct calculations of inclusive cross sections is presented.


The article deals with the question as to how the law addresses the special need for protection of children, adolescents and elderly people in light of the ongoing digital transformation of society. In doing so it will concentrate on the guarantee of self-determination through law. Children, adolescents and elderly people constitute the largest social group that are particularly vulnerable. The digitalization has ambiguous effects. It can reduce vulnerability but can also create new or emphasize existing ones.


OBJECTIVE:To screen serum biomarker candidates in lung cancer patients with bone metastasis using 2-D differential gel electrophoresis(2-D DIGE)and MS.METHODS:The serum samples from 24 lung cancer patients with bone metastases,24 lung cancer patients without bone metastases.The serum samples of the same group were pooled and the most abundant protein albumin was depleted.The concentrated and desalted samples were labeled with three different CyDyes including one internal standard,pooled from all the samples,and separated with 2-D DIGE in triplicate experiments.The biological variations of the protein expression level were analyzed with DeCyder software.The differentially expressed protein spots were analyzed by peptide-fingerprinting with matrix-assisted laser desorption/ionization time of flight mass spectrometry(MALDI-TOF-MS).RESULTS:A total of 11 proteins were found to be significantly increased and 5 significantly decreased in the serum samples of lung cancer patients with bone metastases.The identified proteins included RBP-TTR complex that was decreased,and haptoglobin,SNO-Hb,desArg141 α Hb that were increased.CONCLUSIONS:The combination of 2-D DIGE and mass spectrometry strategy is an ideal platform and powerful approach for differential proteomic analysis of human sera.Four proteins might be involved in the process of lung cancer bone metastases and improve our understanding of the fundamental change that contributes to the process of carcinogenesis and the formation of metastases in lung cancer patients with bone metastases.


The styrene-acrylate emulsion was prepared by compound emulsifier and pre-emulsified core/shell emulsion polymerization technology.The effects of(colloidal)particle size,morphology,emulsifier and core-shell structure composition on the minimum film forming temperature and the glass transition temperature of polymer were discussed.


Objective To explore the clinical curative effect of drug-eluting stents(DES) implantation combined clopidogrel on coronary heart disease(CHD) patients.Methods 73 CHD patients who underwent percutaneous coronary intervention(PCI) were divided into control group(treated with clopidogrel for 12 months,28 cases) and observation group(treated with clopidogrel for 18 months,45 cases).After treated for 2 years,the incidence of acute cardiovascular events,the rate of again to the hospital,mortality were compared.Results The incidence of acute cardiovascular events(10.7% vs 4.4%,P=0.001),the rate of again to the hospital(14.3% vs 4.4%,P=0.001),late incidence of thrombosis(14.3% vs 6.3%,P=0.001) had no significant differences between two groups.After treated,the blood flow indexes of two groups were significantly better than those before treatment,and they were better in observation group than those of control group Long-term effect was good.Conclusions The effect of DES implantation combined clopidogrel treatment CHD is good,and it is worthy to be popularized.


veloped the arginine maturity index (AMI)to estimate the maturity level of peanut fruit and to predict the optimal digging date. Young and Hammons (23) re ported that cultivar and harvesting time affect AMI. 'Spancross', 'Florunner', and 'Florigiant' cultivars were used to determine the relationship between arginine ma turity index (AMI) and other traits in peanut (Arachis hy pogaea L.). Samples were taken weekly beginning 73 days after planting in 1973 and biweekly beginning 77 days after planting in 1974. AMI-l was measured on fresh fruit and AMI -2 was measured on dry seed. The relationship between these two characters was greater than r = 0.85 in each cul tivar tested. Both AMI-l and AMI-2 were positively cor related to percent ofother kernels and negatively correlated to pod yield, and percentages oftotal soundmaturekernels, total kernels, dry matter, and mature seed. Among these cor relations AMI-pod yield was weakest, whereas AMI-percent oftotal sound mature kernels was strongest. The quadratic polynomial, Y = a + bx + cx2,was used to fit the distribution curve for each trait. Florunner and Florigiant appeared to have similar patterns in all traits except percent ofmature seed, but they differed from Spancross in these traits.


Accident patterns can be determined through driving analysis. In environmental, safety, and fleet management applications, accident detection can decrease potential risks to vehicles and drivers, enhance service quality, and save money. Earlier automatic accident detection methods relied on traffic data or external sensors. However, traffic data is difficult to obtain, and external sensors might be untrustworthy and inconvenient. Since traditional techniques have been constrained by a shortage of accident data, cutting-edge technologies such as machine learning (ML) have been underutilized. The most challenging aspect of the task is detecting roadside barriers. The proposed idea is to create something that can identify barriers while driving a car. A Raspberry Pi Camera module aids in the object detection and identification process. The most effective technique for detecting image boundaries is determined by testing on an example image. This study recommends an Advanced Classifier to determine different categories. The proposed technology can identify cars, animals, people, etc. If an object is in the user's route, the system will warn them to slow down. In particular, the proposed Auto-Alert uses both CNN and LSTM models. Importantly, this requires the design and proof of concept of a credible traffic monitoring and density estimation system. The proposed work shows how important CNN and LSTM networks are to help drivers in traffic. Results show that the suggested method is more accurate and faster than the present methodology.


lands, this claim, as I. S. Révah has shown, was disingenuous. Nonspecialist readers in particular might have benefited from discussion of another factor that, along with those that Fisher enumerates, contributed to the bibliocentric character of the rabbinic culture of the Dutch Sephardim. These profoundly Europeanized Jews, many of them rationalistic and cosmopolitan in their outlook and concerned about their image in Christian society, found it difficult to embrace wholeheartedly the rabbinic culture of their time. The Talmud— with its unsystematic structure, associative style, intricate legal reasoning, and concern with "unspiritual" matters—did not resonate with their sensibilities. The Hebrew Bible, in contrast, was a text revered by "everyone" and integral to the brilliant European culture these Jews cultivated. (Moreover, they could be proud to be identified with the biblical Israelites with whom Calvinist Netherlanders, unlike Iberian Catholics, also identified.) Surely it was not because communal leaders prioritized Bible studies that the Dutch Sephardim were so often dismissive of rabbinic law, as Fisher maintains, but rather the other way around. Overall, this is a stimulating and original book. Fisher has excavated a vein of seventeenth-century thought that crossed theological and ideological boundaries in previously unexplored ways. "For the Portuguese Jews of seventeenthcentury Amsterdam," he writes, "the Bible became a fundamentally early modern text" (25): it was now subjected to kinds of scrutiny, by traditionalists as well as radicals, that represented a significant break with the past.


THE PAPER IS A CONTRIBUTION TO THE DEVELOPMENT OF THE FINITE TECHNIQUE IN THE ANALYSIS OF EARTH DAMS. IT IS RECOMMENDED THAT THE FINITE ELEMENT METHOD MAY BE USED WITH CONFIDENCE IN CALCULATING SETTLEMENTS. MATERIAL PROPERTIES MEASURED UNDER APPROPRIATE LABORATORY TEST CONDITIONS ARE NEEDED TO YIELD RESULTS AGREEING WITH ACTUAL OBSERVATION. THE CONFIDENCE WITH WHICH BEHAVIOR CAN BE PREDICTED DEPENDS MAINLY ON HOW APPROPRIATE PARAMETERS ARE THAT HAVE BEEN DERIVED FROM TRIAXIAL TEST DATA. THIS WILL PROVIDE THE KEY TO FUTURE DEVELOPMENTS OF THE FINITE ELEMENT ANALYSIS. AS A DESIGN TOOL, THE FINITE ELEMENT METHOD REQUIRES SOME FORM OF LABORATORY OR SMALL SCALE FIELD TEST TO DETERMINE THE REPRESENTATIVE ELASTIC PARAMETERS. FINITE ELEMENT ANALYSIS OF STRESSES YIELD MORE RELIABLE VALUES THAN DIRECT DETERMINATIONS BY EARTH PRESSURE CELLS. IF A FINITE ELEMENT ANALYSIS YIELDS SETTLEMENTS AGREEING WITH OBSERVATIONS IN THE VARIOUS ZONES OF AN EARTH DAM, THE COMPUTED DISTRIBUTON OF STRESSES BETWEEN THESE ZONES CAN BE RELIED ON WITH A FAIR DEGREE OF CONFIDENCE.