In order to solve the unsteadiness of business process caused by the constantly changing requirements in the Web circumstances, we propose in this paper an automatic configuration method for business process based on rules, with teaching management in colleges as research background. We first define the basic activities of each process and their mutual relations. When it is run-time, business process that satisfies current requirement will be automatically configured according to context and business rules. Any changes of requirement can be reflected in the business rules, so that business process is capable of changing along with requirement without having to alter its applied logic.


FDA HAS SENT warning letters to two Chinese suppliers of the blood thinner heparin, citing them for failure to follow drug manufacturing practices. The letters continue FDA's response to contaminated Chinese-made heparin, which was linked last year to the deaths of at least 80 U.S. patients. One letter went to Shanghai No. 1 Biochemical & Pharmaceutical. It had been shipping heparin to California- based International Medication Systems, FDA notes, although "no drug products made with these lots have been marketed in the U.S." Shanghai No. 1 had assured FDA that it made the heparin, but FDA inspectors auditing the firm last August found that it had in fact been secretly buying the material from two outside suppliers. FDA issued its second warning letter to one of the two manufacturers that had supplied Shanghai No. 1; the other no longer produces the substance. The agency found that at least 19 lots of heparin produced by Qingdao ...


The use of a commercial publisher by a learned society is a solution to a problem. The question then is what is the problem? Learned Societies are by their nature publishers, or communicators, which is of the same kind , but members of learned societies are academics, communicators. rather than professional publishers, which raises the problem. When learned societies publish for the benefit of their members there are few difficulties; it is when they publish for the world at large that they encounter the difficulties of publishing in a professional publishing environment. . The lea rned society purchaser has changed from being a member buying and keeping his own books and journals to an academic using the rapidly developing library facilitie$. The amount of infonnation necessary to an academic vastly exceeds the capacity of his pocket, not only because of the rising prices but also because of the increasing multiplicity of publications generated by the 'information explosion' of the past three decades. · · Publishing has become a totally international and very expert system which requires a large and expensive logistic to support it. Small in publishing is not beautiful if you are producing good publications which deserve a wider audience. The larger learned societies are big enough to establish their own publishing operations, strong enough to compete in the fierce and expert world of publishing ; but the smal ler societies are not. It is an obvious solution for these smaller societies to go to a commercial publisher. The best of these have excellent organizations which will provide for good market penetration . They will provide the expertise and the facilities for publishing without any of the worry. In return for good academ ic material they will pay a royalty without any financial involvement for the learned society . They will also provide copies for members at a reduced price . It is simple , and usually trouble free. Obviously nothing is for nothing. There are disadvantages which have to be taken into account. There is a loss of control over the publication process and the published price. The page budget must be strictly adhered to , style changes are not easily made , there is the need to suppress the name of the society to an extent to allow the publisher's name and logo priority . Publishers are com mercial companies with shareholders ; there must be a profit in the business for them. They put up the capital for which they want a return . The method of distribution is not variable to suit the socie ty 's perception of the market. Books are taken off the list when they cease to be economical , so that either the society allows them to go out of print or has to provide for their handling with inadequate resources after the main revenue has been absorbed. This type of publishing for the smaller learned society is a compromise . An alternative is the Epsilon concept: co-operation within a learned society


Electronic power devices used for transportation applications experience severe temperature variations which promote their thermal fatigue and failure of DBC substrates. The Weibull approach was used to model the brittle fracture of the ceramic layer from a natural defect. Besides, geometric singularities in the upper ceramic/copper interface are at the origin of cracks, which grow by fatigue and finally bifurcate and break the ceramic layer.


The method of system analysis of gating systems designed on the basis of modeling of artificial spatial images temperatures melt filling the form. On the example of the calculated statistical distributions show the sensitivity of the input parameters of artificial image of the temperature field from process time such parameters as the ratio of the gating system feeder, slag catcher and strut.


Does gene expression of human endometrial organoids (EO) mimic the in vivo response to a 28- days substitutive hormonal treatment?

 Gene expression profile of human EO exposed to 28-day hormone treatment showed correspondence with the phases of the menstrual cycle in vivo.

 The recent development of human EO demonstrated their translational potential for reproductive medicine. Current studies testing functional response to hormones of EO are based on short-term responsiveness to estrogen (E2), progesterone (P4) and differentiation factors up to 10 days. It is unknown how organoids can be used to faithfully reproduce and/or model a complete menstrual cycle of 28 days. High-throughput analyses on endometrium have identified specific markers available for characterizing differentiation and functional aspects related to secretory activity and receptivity to implantation.

 Experimental research was carried out including 4 endometrial biopsies donated by women with normal endometrium function, recruited at an academic center for assisted reproduction between 2022-06-15 to 2022-07-28. These endometrial biopsies were processed for organoid derivation and culture. The EO were hormonally treated in vitro and analyzed for gene expression.

 Human endometrial biopsies were enzymatically digested to isolate endometrial glands, embedded in matrigel and cultivated in a spinning bioreactor to achieve organoid formation. Thereafter EO were treated as following: 1) E2: (day 0–28); 2) E2 + P4: E2 (day 0–28), P4 (day 14–28); 3) E2 + P4 + dibutyryl cyclic Adenosine monophosphate (dbcAMP): E2 (day 0–28) + P4 (day 14–28) + dbcAMP (day 14–28) or 4) control group.

 A total of 10 markers were selected for functional analysis and 3 showed a pattern of interest. The target gene expression included Forkhead box O1 (FOXO1), involved in regulating endometrium receptivity in human; progesterone associated endometrium protein (PAEP), a major protein in glandular endometrium secretions; and secreted phosphoprotein 1 (SPP1), an extracellular cytokine that increases in endometrium during the receptive phase.
 Gene expression of FOXO1, PAEP and SPP1 showed a significant increase in the organoids exposed to complete hormonal cycle, compared to controls. PAEP and SPP1 gene expression was lower up to day 21 but upregulated to 15-fold relative to non-treated group by day 28. This pattern recapitulates a similar response to the physiological conditions in vivo in the human endometrium. Although gene expression patterns followed similar trends, individual biopsies had slight variations in gene expression along 28-day hormone treatment.
 The 28 day-hormone treatment can stimulate EO for recapitulating histological and functional aspects. The dynamics resembled a timely correlation with gene expression changes accounting for some specific markers mostly involved in receptivity, and thus reinforcing the potential application of EO for further research purposes.

 In vitro organoid culture conditions may have some influence over responsiveness and gene expression that requires further optimization to reproduce uterine environment in vitro and for other conditions related to infertility in a completely defined culture system.

 Our findings enable the opportunity to expand experimental research over endometrial disorders affecting different stages of the menstrual cycle and also to improve research related to embryo-endometrium interactions.

 This research has been funded by grants from The Swedish Cancer Society, The Swedish Childhood Cancer Foundation, The Cancer Research Funds of Radiumhemmet, The Swedish Cancer Association BRO, the Stockholm County Council (CIMED) and Karolinska Institutet.


evaluation of early assessment tools for earthquake patients. To the The article by Hai Hu, et al is inspiring. 1 The study identified nine independent mortal-ity-related factors that contributed to adult earthquake trauma patients (AETPs) in-patient mortality and constructed an instruction, which is a nomogram, to screen for AETPs with a higher risk of in-patient mortality. This instruction makes sense because it uses simple prehospital factors, which produces great practical value in disaster environments where resources are scarce. However, this instruction is novel and needs to be verified. To verify the effectiveness of the novel instruction in earthquake trauma patients, earthquake casualty data from a tertiary hospital in the 2008 Wenchuan earthquake were studied retrospectively. The patients ' age, respiratory rate (RR), pulse rate, diastolic blood pressure (DBP), Glasgow Coma Score (GCS), crush injury, coronary heart disease (CHD), malignant tumor, chronic kidney disease upon admission, and the outcome (in-hospital death) were collected. Statistical Product and Service Solutions (SPSS) Version 18.104.22.168 (IBM Corporation; Armonk, New York USA) was used to perform a Receiver Operating Characteristic curve (ROC curve) analysis and calculate the Area Under Curve (AUC). In total, 1,847 trauma patients who admitted in the hospital in the 2008 Wenchuan earthquake were extracted from the hospital electronic registration system. Excluding instances that lacked of RR (n = 31), DBP (n = 52), GCS (n = 19), and CHD (n = 34), a total of 1,711 cases were enrolled the study and 38 cases (2.22%) were dead. The


Entrepreneurship education and research is a new area in China.A study on local University,based on survey,after analyzing the problems with china,at the same time,Entrepreneurship education in practice work of local universities was analyzed and summarized.


ABSTRACT We report geological and palaeomagnetic data from five discrete plutons in the southern part of the Peninsular Ranges batholith (PRB) and one pluton that is part of the Jurassic plutonic suite in the Vizcaíno peninsula. The PRB plutons are Cretaceous and belong to the Alisitos island arc. The Jurassic pluton intrudes a Triassic-Jurassic ophiolite. Our study was designed to evaluate the palaeomagnetic homogeneity of the batholith from the Sierra San Pedro Mártir, at ~31°N, to about ~28.3°N. The Punta Prieta, Nuevo Rosarito, San Jerónimo, and La Rinconada plutons in the western zone of the PRB are characterized by magnetizations residing in magnetite. The Compostela pluton is emplaced in a transition zone and has a magnetization that resides in haematite. The five Cretaceous plutons yield a combined palaeopole at 80.3°N, 162.1°E, A95 = 9.8°, N = 5 that after correcting for the opening of the Gulf of California rotates to 77.6°N, 173.6°E, the rotated pole being in angular distance of only 4.4° from the North America reference pole. The Jurassic San Roque pluton yields a mean 0.6°N, 306.1°E, A95 = 9.2°, N = 10, which is discordant, showing a clockwise rotation of about 131° ± 16° and flattening of 9.5° ± 12.9° with respect to the 150 Ma cratonic reference palaeopole. The results suggest that the intrusion of the undeformed Cretaceous Punta Prieta to Compostela plutons (128.1 ± 1.4 and 100.5 ± 2.7 Ma, respectively) restricts tectonic accretion of the Jurassic-Early Cretaceous sequences to the North America margin to the time before mid-Cretaceous magmatism (~100 Ma) in the PRB near present latitude 28°N. Mesozoic and Cenozoic strike-slip faulting along the Vizcaíno margin can account for the 131° clockwise rotation of the San Roque pluton. Our results do not support significant latitudinal movement between Vizcaíno, the PRB, and mainland Mexico with the exception of the Neogene San Andreas Fault-related right lateral movement.


It was written for class discussion and not to illustrate effective or ineffective management practices. Version: 4/1/03. Tarunya Chopra escaped the crowded streets and suffocating heat of her native Mumbai by slipping into the quiet confines of her favorite Internet café. After unloading the heavy collection of textbooks she had carried from her apartment, she logged onto the website of Universitas 21 Global. She expected email from her three teammates, who were located in Shanghai, Kuala Lumpur, and Singapore. A group paper was due the next day in her entrepreneurial finance class, in which twenty-five students from across Asia were enrolled. In addition to finding a draft of the group paper in her inbox, she found a message from her professor, located in England, who was responding to a question that she had asked the day before. Ms. Chopra was over halfway to her MBA degree, a program she had begun a year earlier, in Spring 2003. She had been one of thousands of qualified applicants turned down by the top university in India. While her contemporaries in North America and Europe could fall back on numerous " second tier " choices, Ms. Chopra had few such options in India. Personal and financial constraints prevented her from pursuing her degree abroad. After lengthy discussions with friends and family, and conversations with an agent representing Universitas 21 Global, she had decided to enroll in the online university's first class. The program had proven a good fit for Ms. Chopra's needs. The ability to study anytime, anywhere suited her hectic schedule. She found that while the high-speed connection in Internet cafés was preferable, the University's simple website design was acceptable even over her home dialup connection. She also enjoyed the feeling of being connected to others around the world with similar interests, and felt that it would serve her well as she prepared for a career in international business. Ms. Chopra also valued the tremendous choice she had in determining the total course load at any one time, and the start date of a given course. The University operated on a rolling schedule, and new sections of each course started every few weeks. Since matriculating, she had varied her course load as demands from her part-time job and other commitments required, taking at various times anywhere between two and five concurrent courses. (There was limited flexibility within a course, because once it …


SUMMARY Pronethalol (Alderlin), a derivative of isoprenaline, has proved consistently effective in suppressing the ventricular arrhythmias commonly associated with cyclopropane anaesthesia and occasionally with light halothane anaesthesia. The dose range in adults is 10 to 15 mg intravenously (approximately 0.2 mg/kg). The drug was observed to have no direct effect on the blood pressure or on the periodicity of the sinus and the atrioventricular nodes. It did not alter the conduction time of the pulse wave from the heart to the periphery, as judged by a new system of measurement. There is every indication that pronethalol may be useful in antagonizing the cardiac disturbances caused by the administration of adrenaline to anaesthetized patients.


Background and Purpose— Very few neuroimaging studies have focused on follow-up of subcortical aphasia. Here, overt language production tasks were used to correlate regional cerebral blood flow (rCBF) changes and language performance in patients with vascular subcortical lesions. Methods— Seven aphasic patients were scanned twice with positron emission tomography (PET) at 1-year interval during a word-generation task. Using SPM2, Language-Rest contrast at PET1 was correlated to language performance and to time-lag from stroke. The same contrast was performed at PET2 and session effect (PET2–PET1) was correlated with performance improvement. Results— At PET1, correlation between rCBF and delay from stroke involved mainly ventral regions of the left temporal cortex and mesial frontal cortex. Correlations between rCBF and performance showed predominantly left dorsal regions in the frontal, temporal, and parietal lobes, but also the left ventral temporal cortex. One year apart, language performance improved and rCBF increased in perisylvian regions bilaterally. Best performers at PET2 showed an increase of activity in left ventral temporal cortex as well as in right middle temporal gyrus. Conclusions— On follow-up, expected language improvement and increase of activation in the classical language areas and their counterparts were observed. Moreover, all correlational analyses both at PET1 and on follow-up implicated the anterior part of the left inferior temporal gyrus, suggesting a disconnection between the superior and inferior parts of the left temporal cortex and a specific role for this region in lexical semantic processing.


This paper presents empirical data from a study of the practice of recently graduated engineers working in Portugal and situates the findings in ongoing work to find an appropriate model to categorize the practice of engineering professionals and to draw out useful conclusions for the design of engineering courses and the competences to be developed in them.


Over the years a number of methodologies have been proposed in Software Engineering to deal with systems design. High among them is visual thinking (VT). VT is a well known strategy to foster more ideas and generate consensus within a group. In this paper, we propose the application of VT in the design phase of computational thinking in the K-12 curriculum. The goal is to facilitate the interchange of ideas in a team of students, and assist on orchestrating an all-hands, brainstorming working strategy that ensures that all the participants speak and are listened, and that all the viewpoints are taken into account. We describe the results of an experience of visual thinking applied in the design phase across the K-12 curriculum.


The essence of the debate of philosophy about "Weather is not the moon there when nobody looks?", involve the objective reality of micro-particles during quantum measure. However, the development of quantum mechanics don't deny the objective reality of micro-particles before observed, and only demonstrate micro-particles be of wave-particle duality. What to by the name of quantum mechanics, steal the concept of idealism, in front of the practice of science, be doomed to fail.


Energetic viability of sewage sludge use in agriculture Agriculture, like any economic activity, suffers the current energy crisis. It ́s happen because agricultural systems must be energy sustainable. Several investigators argue reduction of fossil energy input related to fertilizer application for to increase the energy efficiency of agriculture. In fact, the energy expenditure of various cultures indicates high energy consumption of a nonrenewable resource, such as chemical fertilizers. The agricultural application of sewage sludge is well regarded by some producers, because this by-product presents organic matter, macro and micronutrients that can benefit the development of vegetation and soil reclamation. Additionally, this biofertilizer used in partial substitution of mineral fertilizer would decrease the cost of fertilization. So, in addition to environmental and economic gains energy brought by the application of sewage sludge can be a path to positive balances in agricultural production. Thus, this paper examines state of art in agricultural recycling of sewage sludge pointing it as a possible tool for sustainable agricultural systems.


Infant killing in 13 litters of European wild rabbits ( Oryctolagus cuniculus ), born within an enclosed (2.2 ha) population, was recorded. Because interspecific predation can be excluded, female-female competition for a limited number of breeding burrows may have resulted in infanticide.


One of the more satiric barbs in E. E. Cummings's sonnet "the Cambridge ladies who live in furnished souls" is "they believe in Christ and Longfellow, both dead." To make sure that nobody misses the point, Christopher Beach in his Cambridge Introduction to Twentieth-Century American Poetry (2003) informs us: "These 'ladies' still inhabit the nineteenth-century mindset represented by the church and the poetry of Longfellow (the epitome of comfortable literary conventionality); . . . they are not capable of making a distinction between their unthinking religious belief in Christ and their equally unthinking acceptance of inherited literary taste" (104). Student readers of Beach's book, designed primarily for beginners in literary studies, are unlikely ever to have read a line of Longfellow's poetry, but now, thanks to Cummings and Beach, they will be able to acquire their own "unthinking acceptance of inherited literary taste." Christoph Irmscher does not attempt to heave Longfellow back into the canon from which he was expelled by the modernists and critics writing in their wake. The Longfellow whom he reconstructs in Longfellow Redux was, however, "a highly self-conscious writer with a clear and coherent understanding of what he was doing, a writer who apart from being more cosmopolitan, was in some ways even more American than Whitman" (5). Irmscher succeeds splendidly in giving us appreciatory access to Longfellow's clear and coherent understanding of himself as a poet, and provides illuminating readings of numerous poems. His skillful restoration of a poet's work much damaged by the whirligigs of time will not make of Longfellow a "major" poet for our times, but part of his case for taking a fresh look at Longfellow two centuries after his birth in 1807 is that customary assumptions affecting our ways of bestowing "major" and "minor" labels simply do not apply in his case. Longfellow's readership spanned social classes, generations, and continents as no other American poet's has before or since. In "Strangers as Friends: Longfellow and His Readers," the first of four chapters, Irmscher writes of how strangers would approach Longfellow on the street and come calling unannounced at his house on Cambridge's Brattle Street, where he kept a box of autographed photos on the mantelpiece for such occasions. He also received a daily avalanche of letters from readers who sought to strike up a correspondence with him. Over the course of a long literary lifetime, he received more than twenty thousand letters from admirers, who often included generous samples of their own work, thirteen hundred requests for autographs, and hundreds of birthday letters. Longfellow spent hours writing as many as twenty replies per day, a regimen which led John Greenleaf Whittier to remark: "My friend Longfellow was driven to death by these incessant demands." Why did so many utter strangers when writing to him readily address Longfellow as their friend? What was the nature of the appeal of his poetry to them,


Applying the K+ channel origami windmill model principle, the whole process of action potential generation of nerve fiber cells and cardiomyocytes is explained reasonably. Its core view is: cell action potential decline phase, dominated by influx of potassium ions. This is contrary to the core idea of the traditional theory—ionic theory. According to ionic theory, cell action potential decline phase, dominated by outflow of K+ ions.In the face of such two opposing views, the author traces back to the source, combing and commenting on the basic theoretical research on the production mechanism of cell bioelectricity generation and the results of classical basic experiments. And a series of enlightening viewpoints are produced:1. Ionic theory has its preexistence deficiency; 2. There are principle defects in GHK equation and H-H equation; 3. Ion channels may "same direction sharing"; 4. Sodium-potassium pumps, calcium pumps and so on May not exist.The thesis's Point is falsifiable. If "cell action potential decline stage, dominated by outflow of K+ ions" can be proved, all the points in this paper will not be true. On the contrary, the series of enlightening views in this paper will inevitably lead to a revolution in the field of life science. The viewpoint of this paper is not only closely related to the causes of human major diseases, treatment principles and methods, but also may have a profound impact on the future research direction of life science researchers.So the author suggests that scholars in the field of life science should re sort out the existing bioelectricity knowledge system—eliminate the false, save the true and clear the source, especially focusing on the papers published by Hodgkin and Huxley in 1952; At the same time, it is necessary to reevaluate the scientificity and scientific value of membrane theory, ionic theory, GHK equation and H-H equation, and put forward new theories based on Bernstein membrane theory, and establishing a new mathematical model of cell action potential.


Floating drug delivery systems developed with Chitosan having internal cavities were prepared by deacidification. When added to acidic (pH 1.2) and neutral (deionized water) media, these granules were immediately buoyant and provided a controlled release of the candidate drug prednisolone. Laminated preparations prepared by coating the chitosan granule's layer with chitosan membranes were also immediately buoyant and provided controlled release profile of the drug. According to the authors, this might be explained by the fact that the laminated preparation has higher inter-subject variation and higher pH-dependency of the drug release than the chitosan granules. However, both the chitosan granules and the laminated preparations could be helpful in developing drug delivery systems that will reduce the effect of gastrointestinal transit time 152 .


The phosphatase and tensin homology deleted on chromosome ten(PTEN) gene is severely lost in tissues of endometrial carcinorma,which is a hot topic in research of the tumorigenetic mechanism of endometrial carcinoma.PTEN regulated cell growth,proliferation,apoptosis and angiogenesis by regulating three down stream signaling pathways such as 3-kinase phosphatidylinositol/protein kinase B/mammalian target of rapamycin(PI3K/Akt/mTOR),focal adhesion kinase(FAK) and mitogen-activated protein kinase(MAPK) pathways.The loss or mutation of PTEN causes tumorigenesis.This review summarizes the current research on association of PTEN and epidermal growth factor receptor(EGFR) and their downstream signaling pathways with tumorigenesis and development of endometrial carcinoma to provide theoretical evidence for gene diagnosis and gene therapy of endometrial carcinorma.


Both one- and two-dimensional optically-induced photonic lattices with single-site negative defects are realized experimentally, in which light confinement as defect modes is clearly demonstrated. Our experimental results are in good agreement with theoretical predictions.


Under the more electric aircraft (MEA) theme, many aircraft systems are being electrified. In a previous research work, an electric starter generator system for aircrafts was implemented. This paper presents the reliability of the drive converter – a 3 level neutral point clamped converter (3L-NPC) under an expected mission profile of a short haul aircraft. Wearout failure based reliability of semiconductors and capacitors are considered along with reliability of gate drivers to estimate the overall reliability of the converter.


Previous research suggested that category spanning causes products to receive lower evaluations by audiences. We question this notion and propose that the effects of category spanning depend on the category system in which spanning occurs: in a system where memberships are determined by shared features, spanning can engender ambiguity and decrease products' appeal; however, in a system where memberships are based on audiences' goals, spanning can imply versatility and lead to better evaluations. Furthermore, we argue that these effects are different if products concurrently span categories in both systems. Our analysis of audiences' evaluations of products in the commercial music industry supports these hypotheses: spanning categories in a goal-based system has a U-shaped effect, and whereas products with focused features benefit from having more goal-based memberships, products with heterogeneous features benefit from having fewer. The implications of these findings for the organizational literature are ...


This thesis attempts to deepen our understanding of the democratic assignment for Swedish schools. The school is a public space that all children and youth are a part of which gives it a prominent ...


Geolocalized databases are becoming necessary in a wide variety of application domains. The manual creation of such databases is an expensive operation which stimulated the interest for the automation of their construction, by mining geographic information from the Web. In this article, we present and evaluate a new automated approach for creating a geographical database. Our technique uses Wikipedia to identify geographical names, categorize them, find their geographical coordinates and rank them according to some relevance creterion. This database has been integrated in ThemExplorer, an application for geographic image retrieval. MOTS-CLES : Bases de donnees georeferencees, Wikipedia, extraction d'information, fouille de donnees, ThemExplorer.


Objective To study lifestyles of youth with high education level in China, and to provide evidence for the intervention of health risk behavior. Methods By using a self-designed questionnaire, 6 000 residents in the age between 20-29 years old and with education level of bachelor in 30 provinces, municipalities and autonomous regions throughout China. The difference of lifestyles were compared using geographic information systems (GIS). Results The youths in developed area sit longer than other areas, especially in female. The frequency of physical activity among youths in coastal area was more than inland area, and the activity time was the most reasonable in Heilongjiang, no region difference was found among other provinces. The life well-being in southeast coastal area was better than in northwest inland area of China. The stress of female youths with high education level in east coastal area and central plains area was stronger than northwest area, but it was quite the contrary in male. Female youths were living more regularly and more of them had breakfast everyday, but male youths had more in spare time. More youths had breakfast in Guangdong, Guangxi and Zhejiang. Female youths in Guangdong and male in Shanghai had more amusements in spare time. Conclusion Effective measures should be taken among youths with high education level in China for their unoptimistic life styles.


A theoretical study for the ionization from several orbitals of the water molecules in liquid phase by electron impact is presented. Multiple differential cross sections are computed through a first order model considering an asymmetric coplanar geometry. The wavefunctions for a single liquid water molecule are obtained in a realistic way by using a Wannier orbital formalism. The comparison with previous theoretical results as well as experiments for the gas phase shows a qualitative agreement. Moreover, an analysis of the influence of the passive electrons is performed by the assistance of different static potentials.


The explosive growth of Internet and other "new economy" companies has led many firms venture capital firms as well as old-line industrial and financial services companies to explore ways of participating in that growth by forming what are popularly called "incubators." Incubators are typically organizations that foster startup companies by providing them with a package of the basic services they need to help them grow into viable businesses. These services may include management advice, access to capital, legal, and accounting services, technical support, office space, help in preparing business plans, and general "adult supervision." Incubators are not new. The first was formed in 1959 in Batavia, New York, in a vacant farm equipment factory. 1 With the rise of the Internet, however, the number of incubators has increased dramatically. Prominent Internet-focused incubators include CMGI, Internet Capital Group, idealab!, and Softbank. What accounts for the popularity of this business development model? For one thing, it recognizes that many excellent new business ideas are generated by people often fairly young people who lack the business experience necessary to execute them. Second, the incubated businesses can benefit from the synergies possible from their relationships with other similar businesses under the incubator's aegis. (Incubators and their investee companies are sometimes called "keiretsu," the Japanese term for


Single-mode fiber lasers are capable of supporting trapped vector solitons with two similar orthog-onally polarized components, due to the delicate balance between fiber birefringence and chromatic dispersion. Here, we demonstrate that heterogeneous vector pulses (HVPs) universally exist in anomalous-dispersion and near-zero-dispersion regimes, from hybrid-structure fiber lasers composed of low-and high-birefringent fibers. The vector pulses include two distinct orthogonally polarized components, one of which is a robust pulse, while the other is a gradually attenuated wavepacket composed of terahertz-(THz) repetition-rate subpulses. Simulation and analytical results fully reproduce experimental observations and demonstrate that the robust pulse couples a fraction of its energy to the orthogonally polarized component per roundtrip at the high-birefringent fiber, forming the unique HVPs. Apart from the intriguing nonlinear dynamics, the HVP can work as a flexible workhorse for various applications, ranging from optical polarization multiplexing to THz synthesis and optical precision spectroscopy.


Objective To assess the diagnostic value of clinical pretest probability prediction rules for the pulmonary embolism by retrospective case series.Methods 688 inpatients were assessed by the Wells score,the Geneva score and the revised Geneva score respectively.According to the three scales,the probability of pulmonary embolism of every patient was analyzed and the patients were divided into the low,intermediate and high probability group.The result of CT pulmonary angiography was used as the diagnostic gold standard of pulmonary embolism.Results There were 198 cases diagnosed as with pulmonary embolism by CT pulmonary angiography.All cases were performed the Wells and revised Geneva score.Because 198 cases did not have the arterial blood gas results,so 490 cases were performed the Geneva score.The prevalence of pulmonary embolism in the low probability group was Wells score 14.2%;Geneva score 17.2%;revised Geneva score 17.1%.The prevalence of pulmonary embolism in the intermediate probability group was:Wells score 53.9%;Geneva score 40.0%;revised Geneva score 36.4%.The prevalence of pulmonary embolism in the high probability group was:Wells score 75.9%;Geneva score 47.1%;revised Geneva score 62.9%.The area under the receiver operating characteristic curve of the Wells score(0.8195)was the highest,and there was significant difference compared with the other two scales.Conclusion Compared with the Geneva score and the revised Geneva score,the Wells score had the highest prediction accuracy for pulmonary embolism among inpatients.


Spiders were collected by using ground pitfall trap and shaking method (vegetation beating). Pitfall-traps were practiced once every week in four medicinal and ornamental crops in Fayoum Governorate. A total of 315 spiders of 22 species, 2lgcnera and 15 families were collected, from 320 pitfalls and shaking method collections from of March, 10 to end of August, 2010. The family Lycosidae, was found to be the dominant in the four experimented fields, recording 159 individuals, representing 74.6 % of the total ground collected fauna; followed by the family Philodromidae which represented 20.1 % of the total of aerial collected spiders and being abundant in Red pepper vegetation. The composition of ground collected spider and their densities differed in the four vegetations from that of the aerial collected spiders. The activity densities of ground collected spider communities in the Spearmint, Castor bean, Roselle and Red pepper recorded 34, 64 and 73 and 45 individuals respectively, while those of aerial collected spider were 63 , 7 and 29 individuals in Spearmint, Castor bean and Red pepper. No spiders were collected from vegetation of Roselle plant. Community composition of the ground and the aerial collected spiders were determined throughout the period of study using the Shannon-Wiener and Simpson Indices of diversity. Obtained results revealed that species diversity differed in the two communities. Monthly fluctuations of the total number of spiders showed high populations in June.


TheGolgi apparatus isfragmented anddispersed inVerocells butnotinhuman143TK-cells infected with wild-type herpes simplex virus 1.Moreover, a recombinant viruslacking thegene encoding themembrane protein UL20(UL20- virus) accumulates inthespacebetween theinner andouternuclear membranes ofVero cells butisexported andspreads fromcell tocell in143TK-cell cultures. Herewe reportthatinVerocells infected withUL20-virus, thevirion envelope glycoproteins were oftheimmature type,whereas theviral glycoproteins associated withcellmembranes were fully processed up totheaddition ofsialic acid, a trans-Golgi function. Moreover, theamountsofviral glycoproteins accumulating intheplasmamembranes were considerably smaller thanthose detected on thesurface ofVerocells infected withwild-type virus. In contrast, theamountsofviral glycoproteins present on theplasmamembranes of143TK-cells infected with wild-type orUL20-virus werenearly identical. Weconclude that(i)inVerocells infected withUL20-virus the block intheexport ofvirions isattheentry into theexocytic pathway, anda second block intheexocytosis of viral glycoproteins associated withcytoplasmic membranes isduetoan impairment oftransport beyondGolgi fragments containing trans-Golgi enzymes andnottoa failure oftheGolgioligosaccharide-processing functions; (ii) these defects aremanifested incells inwhichtheGolgi apparatus isfragmented; and(iii) the UL20protein compensates forthese defects byenabling transport toandfromthefragmented Golgi apparatus. Herpes simplex virus 1(HSV-1) encodes numerous glycoproteins andnonglycosylated membraneproteins whichfunction invirus entry, virion envelopment, sorting, andegressfrom infected cells. Thespecific issues addressed bythisreport involve viral maturation andother eventswhichtakeplace concurrently. Specifically, viral capsids areenveloped atthe


This correlational research aims to study socio - population character, inputs, process, knowledge and attitude factors that affected the success of universal coverage insurance in hospitals in Surin province. The study also determines the level of their effect on success of universal coverage insurance. The study used 712 cases (384 clients 328 health care providers) as its sample size. Sampling method was multi - stage random sampling studied in Surin hospital, Sumrongtab hospital, Prasat hospital and Primary care units during February to May 2003. Instrument was questionnaire and reliability was 0.96. The method of analysis was calculated and presented by percentage, mean, standard deviation, multiple regression analysis, stepwise multiple regression analysis, frequency and conclusion. The results were as follow :  1.  The socio - population character. Client groups (53.9%) have average age of 30 years old; their occupation were farmers, sellers, students and employees (13.5 % equally in all category). Educational status was lower than a diploma (47.4 %), diploma (3.5%) and bachelor , s degree (3.2%). Health care provider groups (46.1%) have average age of 34 years old. The position were practitioners (35.1 %) and managers (11%). Educational status was bachelor ,s degree (27.5 %), diploma (10.5 %), lower than a diploma (4.3 %) and a master ,s degree (3.8%).  2.  Input. Both overall and particular factors (such as man, planing, budget, place, equipment and accommodation) were considered as moderately appropriate.  3.  Process. Both overall and particular factors (such


Pathogens change forest composition and structure by selectively eliminating susceptible individuals and species. Caused by a complex between an exotic scale insect and fungi, beech bark disease has infected mature American beech (Fagus grandifolia) trees through most of the species range. Before succumbing to the disease, infected trees generate root sprouts, transforming beech from a dominant canopy species into an abundant subcanopy species. Root sprouting can create dense beech thickets that interfere with the regeneration of other species. Exclusion of species from the understory has ecological and economic implications. This study compared forest CQmmun..ity types for their resistance to CQmpositional and structural change from beech thickets. The expansion and density of beech sprouts, as well as the density of other species in the thickets were measured in seven different forests in central Maine. Mixed hardwood forests, specifically an ash-birch-maple forest, tend to be most resistant to change, while a hemlock-pine-oak forest was least resistant. This information may be useful for managers to prioritize forest community types in which to control beech thickets.


Catalytic total oxidation is important in several applications. However, associated models are rather empirical. In this study, a microkinetic model is developed for ethane total oxidation, under f...


Some 20 of ca. 200 verbs of Tura, an Eastern Mande language of Ivory Coast, contain a derivational suffix |-LA|. The primary function of this derivational affix is to mark on the verb the deletion (or sometimes facultativity) of the argument that is normally obligatorily expressed with the base verb as an oblique case object or an adverbial. This kind of derivation, which I propose to refer to as (locative) deobliquative, is typologically unique. The removal occurs either when the respective argument is referentially indefinite, i.e. it can be rendered with 'somewhere, anywhere', or when it is coreferential with the subject or the direct object. In this paper, I discuss the latter, reflexive locative type of the deobliquative derivation by way of a detailed comparison of the verb gbie 'pull (at) somebody, something' and the derived verb gbiela 'drag somebody, something along, away (on the ground)'.


The Greater Los Angeles County Region, comprised of five subregions, spans from Ventura County to Orange County, and from the coastline to the San Gabriel Mountains an area representing over 10 million people and over 2,200 square miles. The Region consists of approximately 28% of the State's entire population, encompassing 92 cities. While water is one of the Region's most valuable resources, there are extremely complex water quality and water supply issues. An integrated approach to water management is the way to address a broad range of water resource management issues, competing water demands, water supply reliability, and financing of projects. Hundreds of local agencies, organizations, cities, and county governments are participating in the Integrated Regional Water Management Plan (IRWMP) effort for the Greater Los Angeles County (GLAC) Region that is inclusive and provides opportunities for cost-effective solutions to address the water resource needs of the Region. The IRWMP will serve to position the Region for obtaining funding from local, State, and Federal sources to implement projects. Since the Region's IRWMP group was formed, there have been numerous accomplishments. This paper will cover successes through stakeholder collaboration such as project implementation and grant acquisition, lessons learned, and vision for future water management integration in the Region.


This paper discusses the various distance learning techniques for the web. The fundamental concepts of distance learning and relevant technologies, such as videoconferencing, audio conferencing, online courses, web conferencing, and print media are discussed. Implementation examples using Internet for distance education are highlighted thru examples.


Enormous progress has been made during the past five decades in the area of adaptive array processing. Increased computational power has resulted in many practical applications of optimum algorithms. The present paper deals with many facets of array signal processing and adaptive beam forming. It provides a comprehensive description of various beam-forming schemes, adaptive algorithms to adjust the required weighting on antenna elements, direction-of-arrival estimation methods, including their performance comparison. The effects of various types of errors on the performance of an array system are illustrated along with their remedial measures. Since array signal processing has widespread applications, the study is carried out across various disciplines.


Immobilization of Mortierella vinacea cells, which contain active ..cap alpha..-galactosidase, by radiation polymerization at low temperatures was studied. The durability of the enzymatic activity of the immobilized cells obtained with hydrophilic monomers was affected by the concentrations of the cells and monomer in which optimum conditions were observed. The enzymatic activity of the immobilized cells obtained with hydrophilic monomers was compared to that of hydrophobic monomers. Michaelis constants of the immobilized cells varied with monomer concentration. The effect of addition of porous solid substances on the immobilization of the cells was studied.


Hydrocyclones are equipments that separate a discrete phase (solid, liquid or gas) from a continuous phase (liquid) by generating a centrifugal field. The objective of this work was to study, experimentally, the incorporation effect of cylindrical and conical permeable walls (CyCoFH) on an optimized geometry hydrocyclone (H11) to evaluate the equipment's processing capacity. By inserting a filtering cone and cylinder, during the operation of these separators, besides the traditionally observed streams (underflow and overflow), there is an additional liquid stream resulting from the filtering process in the conical and cylindrical regions. Despite the low filtrate flow observed during this new equipment's operation, it was found that the filtration is benefic to hydrocycloning. According to the main results, the CyCoFH hydrocyclone of lower permeability presented a greater processing capacity. The feed flow rate was 23% higher than the corresponding conventional hydrocyclone, in the same geometrical and operational conditions.


There is an increasing requirement for mental health services to
demonstrate the quality of care provided. We have developed a quality report
of our local community mental health team in Cornwall and suggest quality
measures that we believe are useful to patients and clinicians, and possible
to implement without overwhelming busy team members. They include measures of
satisfaction, accessibility, safe process and review, outcomes, evidence-based
practice and staff performance. Different teams may need different standards
but we hope this paper will stimulate discussion and debate.


Abstract.  Laboratory studies investigated the development of teratocytes derived from the eggs of the parasitoid Meteous gyrator (Thun.) in its host, the tomato moth Lacanobia oleracea (L.). At hatching, each parasitoid egg produced an average of approximately 1000 teratocytes, but this number declined to approximately 400 during the course of parasitism. The teratocytes increased in size markedly, such that 7 days after egg hatch their mean diameter was approximately four times that of the cells immediately after dissociation. The haemolymph of parasitized hosts had reduced phenoloxidase activity, and teratocytes inhibited phenoloxidase activity when coincubated with plasma from nonparasitized hosts. The injection of teratocytes into nonparasitized fifth‐instar L. oleracea larvae suppressed growth and induced a supernumerary moult in some larvae. A number of parasitism‐specific proteins were detected in the haemolymph of parasitized hosts, and incubation of teratocytes in culture media indicated that these cells were a source of at least two of these proteins.


This research was conducted to find out the effect of aqueous extracts of different Botanicals against the rice root-knot nematode, Meloidogyne graminicola in laboratory and Screen house conditions at CCSHAU, Hisar. Aqueous extracts from plant leaves were screened for nematode mortality against second stage juveniles (J2) and egg hatchability of M. graminicola. The nematode juveniles and eggs were exposed to 48h and 10 days to different dilutions (100%, 50% and 25%) of botanical extracts respectively. All the treatments significantly increased the percentage of mortality at 48 h. of exposure in aqueous extracts concentration (100%, 50% and 25%) as compared to control (Nematode alone). At 48 h. (100% concentration) the maximum mortality percent was found in Neem (Azadirachta indica) 89.00%, whereas in egg hatching experiment with the dilutions as 1:10, 1:20, 1:30, 1:40 and 1:50 were prepared by diluting stock solution. The Neem (Azadirachta indica) at 1:20 (v/v) dilution significantly reduced the egg hatchability and it was followed by Cauliflower (Brassica oleracea var. botrytis) and Cabbage (Brassica oleracea var. capitata).


Large deployable reflectors are the key technical equipment to meet the needs of geostationary mobile communication in high rail and earth observation. After being sent to the working track by the spacecraft, the space antenna is driven by a reliable and stable controller to provide a frame for forming a high-precision metal reflecting surface. This paper aims to study the optimal deployment process control strategy and method based on the deployable trajectory for a large deployable antenna. In this paper, the Backstepping controller and fuzzy PID controller are designed respectively based on the model and non-model perspectives. The feasibility of the controller is verified by simulation, and the advantages and applications of the controller are illustrated by comparison. The article lays a good foundation for the technical improvement of the antenna system.


Despite all the importance of strategic planning in organizations of the private industry, similar experiences described in the public administration context are rare. Furthermore, the methodologies used in these cases are neither clear nor consolidated as they should be, because they are, in general, adaptations from their parallels of the private sector. This article aims at identifying the main elements concerning the Situational Strategic Planning (PES) methodology, and its adoption by the Tributary Administration Coordination (CAT) of the State of Sao Paulo. It consists of an exploratory study, introducing a notorious experience within the Brazilian tributary administration, which qualifies for a unique case study method. The text investigates: the main aspects of strategic management in the public administration; the process of strategic planning inside CAT with the PES adoption; the main results achieved; and, finally, the conclusions considering the case context.


tribute to the formation of the quality and function of miso. Lipases catalyze the hydrolysis of glycerides of soybeans and the synthesis of esters during miso fermentation,2) so that the fiavors and tastes are formed. However, there have been only a few reports about lipase from A. oryzae.3'`} Therefore, it is necessary to investigate the properties of these lipolytic enzymes and elucidate their roles to identify the mechanism of the change in lipids during mtso ferrnentation. A. or),zae produces at Ieast two extracellular lipolytic enzymes, Ll and L2, with diiierent substrate specificities.S) Both of these enzymes have been purified and characterized.6J) Ll, a cutinase-like enzyme, has a high specificity toward dimercaptobutyrate, and L2 hydrolyzes monoacylglycerols and diacylglycerols, but not triacylglycerols. Cloning and nucleotide sequencing of the genes coding for the enzymes has been done.8・9) We are interested in their substrate specificities, but triacylglycerol lipase, a third enzyme, seems to be the most important enzyme in its action during mtso fermentation. Triacylglycerol is the main lipid in soybeans. However, triacylglycerol ipase isolated from A. or "zae has not yet been reported. In a proj ect done to obtain enough of the purified protein for further study, we selected A. oryzae RIB128 as the most productive strain tested.iO) We also selected a suitable medium and culture conditiens for production of the lipase.'O) In this paper, we describe the purification and characterization of triacylglycerol lipase, designated L3.


Equipment installation acceptance procedures together with functional purchasing specifications can effect a means of user self analysis and provide viable communications between equipment suppliers and users.


Background: Incidence of laryngeal cancer still high among the upper aerodigestive tract. 85–95% of these laryngeal cancer is squamous cell carcinoma. Locally advanced laryngeal cancer metastasize more. Supraglottic cancers have the highest prevalence of regional metastases among laryngeal cancers.
Objectives: To evaluate the frequency of regional metastasis in supraglottic carcinoma of larynx.
Methods: This cross-sectional study was conducted including 40 patients with supraglottic Carcinoma of Larynx over a period of six months from June to November 2014 in the ENT and Head Neck Surgery department of Rajshahi Medical College Hospital, Rajshahi. Those with glottic carcinoma, subglottic carcinoma, hypopharyngeal carcinoma, metastatic neck node without any primary site (Occult primary) were excluded from the study. FNAC from neck node was done in patients with palpable neck node.
Results: Most of the patients 19 (47.5%) was in age group 50-60 years with mean age 54.5±13.2 years. Most of the patients present with more than one symptom & the commonest presenting symptoms was cough and irritation 35(87.5%) followed by dysphagia 26(65%) and change of voice 24(60%). A good number of patients, 16(40%) was presented with neck swelling. Among 40 patients, 16(40%) had their regional lymph nodes involved. Level-II lymph nodes were involved in higher number of cases 10(62.5%). Nodes in early stage of involvement were found in most cases 9(56.5%). Homolateral involvement of nodes was found in most cases 13(81.3%).Most of the supraglottic growths 22(55.0%) was exophytic in appearance. The common site of supraglottic carcinoma in this study was aryepiglottic fold and arytenoids 20(50.0%). Among the patients, 31(77.5%) had T2 tumours. Amon them, 16(40%) were in stage-III followed by stage-II 10(25%).
Conclusion: Regional metastasis is a very useful prognostic indicator. Supraglottis is rich in lymphatic drainage and a high proportion of these tumors spread to lymph nodes.
Bangladesh J Otorhinolaryngol 2022; 28(2): 180-185


Intra-cerebral hemorrhages are a known cause of significant mortality and morbidity, among all the different forms of stroke. Primary multiple simultaneous intra-cerebral hemorrhages (MSICHs) are not common and has been reported in association with other diseases. There are only around 105 cases reported. The diseases most commonly associated are thrombophilia and hematologic disorders, vasculitis, neoplasms, arterio-venous malformation, anticoagulant therapy, illicit drug use, or multiple infarction with hemorrhagic transformation. Though the outcome is not much different, probably marginally worse compared to a regular stroke. Herein we describe a middle age male with hypertension who was referred to us with basal ganglial bleed.


The Belianske Tatry Mts. represent one of the typical and valuable karst regions in the Western Carpathians. In the present climatic conditions, the karst relief is under intensive modeling and denudation by erosion factors in which karst processes hold an important place. Karst creation is in principle chemical erosion in which oxidation, hydrolysis, hydration, and other chemical reactions cause partial or total weathering and erosion of rocks depending on rock structure under certain physical conditions. In the Belianske Tatry Mts., not only Mesozoic rocks from the Triassic, Jurassic, and early Cretaceous periods but also mid Triassic Ramsaus dolomites are affected by weathering and erosion processes. Chemical weathering of Mesozoic carbonates is supported by reaction of sulfuric acid with pyrite and markasite in the zone of hypergenesis. This process leads to developmerit of several types of secondary chemoge-nous minerals. The newly detected minerals belong to the group of sulfates, oxides, and phosphates according to the Belechtin's classification. Limonite (α-FeOOH) represents the group of oxides. Limonite has been found in kar-sted holes opened by mining in quarry in the Tatranska Kotlina. Geothite was proved by the rontgenodiffractive method. The mineral was precipitated in the cavity karst soils in the cavities of carbonate-dolomite complex in the Buja-ci Mt Similar fragments of aggregates were detected on the mountain ridge in the area of the Predne Jatky Mt. From the secondary sulfates, gypsum (CaSO4 . 6H20) is the most common. It is found in the two different geological positions. On the first place, it creates crystalline forms of water white or white color in the high mountain Alabastrova cave. Hypotheses regarding its origin are still unclear. On the second place, quantitatively greatest amount of secondary gypsum was detected around the Stary Mt. Hexahydrate (MgSO4 . 6H20) was found in the quarry in the southern edge of the Palenica Mt It occurs in the thin layers of white and pale grey color, opaque lustre, covering weathered rocks. Sulfates in origin are directly and closely tied to chemical processes in the acidic rock base. Secondary phosphates are represented the most probably by carbonatehydroxil apatite -dahllite [Ca5(PO4,CO3)3(OH)]. It was determined by the analogous occurrence in the cave V Zaskoci in the Nizke Tatry Mts. published by Cilek and Komasko (1984). Firstly, it was detected in the cave Novy c. 2 in the massif of the Novy Mt, where it occurs in pale-dark brown very thin opaque coats covering dark grey early Cretaceous limestone. Secondary phosphates originate from the mineralized solutions containing ammoniate phosphates and sulfates originating from the bat excrements.


We present a new web-based learning software that uses three basic psychological effects: incidental learning, increased motivation and technique we call the "Tamagotchi-Effect". This software is called "VR-Friends" and represent a kind of Internet-based virtual learning-companion. With the concept outlined of a learning software implemented as a gameshow, an attempt is made to make users learn without always being reminded that they are learning. Ideally users should be able to play with the game without knowing at all that they use learning software. The VR-Friends system consists of a collection of several client and server programs. According to the philosophy of client/server systems the individual programs can be distributed among several computers, thus forming an open system. The communication between the modules is realized by plain text commands that are transferred between client and server by means of the TCP/IP protocol.


Proteins containing unnatural amino acids have immense potential in biotechnology and medicine. We prepared several histidine analogues including a novel histidine analogue, beta-(1,2,3-triazol-4-yl)-DL-alanine. These histidine analogues were assayed for translational activity in histidine-auxotrophic Escherichia coli strain UTH780. We observed that several histidine analogues, including our novel histidine analogue, were efficiently incorporated into the protein in vivo; however, other analogues were rejected. These results suggest that the hydrogen atom at a specific position seriously affects incorporation.


Background: Obesity-induced inflammation is characterized by macrophage migration and polarization; signaling regulation therein remains poorly understood. Results: Lipid-induced fetuin-A from adipose tissue acts as chemoattractant for macrophage migration and also polarizes adipose tissue M2 macrophages to proinflammatory M1 subtype. Conclusion: Adipocyte fetuin-A is a novel signaling molecule in lipid-induced tissue inflammation. Significance: These findings have revealed an unseen area of inflammation. Macrophage infiltration into adipose tissue during obesity and their phenotypic conversion from anti-inflammatory M2 to proinflammatory M1 subtype significantly contributes to develop a link between inflammation and insulin resistance; signaling molecule(s) for these events, however, remains poorly understood. We demonstrate here that excess lipid in the adipose tissue environment may trigger one such signal. Adipose tissue from obese diabetic db/db mice, high fat diet-fed mice, and obese diabetic patients showed significantly elevated fetuin-A (FetA) levels in respect to their controls; partially hepatectomized high fat diet mice did not show noticeable alteration, indicating adipose tissue to be the source of this alteration. In adipocytes, fatty acid induces FetA gene and protein expressions, resulting in its copious release. We found that FetA could act as a chemoattractant for macrophages. To simulate lipid-induced inflammatory conditions when proinflammatory adipose tissue and macrophages create a niche of an altered microenvironment, we set up a transculture system of macrophages and adipocytes; the addition of fatty acid to adipocytes released FetA into the medium, which polarized M2 macrophages to M1. This was further confirmed by direct FetA addition to macrophages. Taken together, lipid-induced FetA from adipocytes is an efficient chemokine for macrophage migration and polarization. These findings open a new dimension for understanding obesity-induced inflammation.


Patients with end-stage renal disease (ESRD) will inevitably develop some degree of anemia due primarily to relative erythropoietin (EPO) deficiency. Successful treatment of anemia includes not only the use of recombinant human EPO but also iron supplementation. Recent practice guidelines suggest that iron-deficient peritoneal dialysis (PD) patients should receive 500 mg to 1000 mg intravenously as needed if they cannot tolerate oral iron therapy (1). Administration of iron via this route is not very convenient for PD patients because they must have a scheduled appointment for the 1 hour infusion of iron dextran. An alternate route of administration for iron would be ideal for these patients. Recently, it has been shown that intraperitoneal (IP) iron may be an effective route of administration (2). This route has been shown to be useful for many other drugs, including antibiotics and insulin. In order for this route to be used on a routine basis, the stability of these compounds must be stud ied. The stability of iron dextran (INFeD, Schein Pharmaceutical, Florham Park, NJ, U.S.A.) has been studied, but not in concentrations yielding recommended repletion doses, nor with an assay that was stability indicating (3). The stability of the other iron dextran product currently available in the U.S.A. (DexFerrum,American Regent, Shirley, NY, U.S.A.) has not been studied in PD solutions. We therefore studied the stability of iron dextran in PD bags using currently recommended doses (lOO mg, 500 mg, and 1 g). MATERIALS AND


The migratory system of sheep rearing takes two forms i.e., temporary and permanent migration. In temporary migration, due to lack of fodder and grazing lands in their natives shepherds migrate with their flock during the rabi season and return to their natives along with their flock during the onset of monsoon. During this period shepherds move from one place to another for 6-7 months relying on the crop residues of cultivated lands for feeding their sheep. In this type of migration the men may or may not be accompanied by their families. Other families may stay in their native place being engaged in agricultural work or agricultural wage earners. International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 10 Number 02 (2021) Journal homepage: http://www.ijcmas.com


ABSTRACT Liquid–liquid extraction of carbonate and mixed peroxo-carbonate compounds of U(VI) and Am(III) from Na2CO3 aqueous solutions by methyltrioctylammonium carbonate in toluene has been studied. The main patterns of effect of extractant, Na2CO3, and H2O2 concentration on distribution and separation of U(VI) and Am(III) have been established. Using slope analysis and UV–vis spectroscopy, the compositions of U(VI) and Am(III) extractable compounds are established as (R4N)4[UO2(CO3)3], (R4N)4[UO2(О2)(CO3)2], and (R4N)6[(UO2)2(O2)(CO3)4] for U(VI); R4N[Am(CO3)2] and (R4N)3[Am(CO3)3] for Am(III), where R4N is the quaternary ammonium cation. The obtained data showed high efficiency of the studied carbonate system for extraction of U(VI) and its purification from Am(III). The maximum separation factor of U(VI) and Am(III) was 25.


Titanium and zirconium are playing an increasingly greater role in industry as corrosion-resistant materials for use in severe environmental conditions. Their applications in a variety of environments are reviewed. Discussion also focuses on potential new areas where titanium and zirconium can be expected to find application because of their mechanical and corrosion-resistant properties.


Results of designing the construction of the gas flow restrictor, which is destined for disconnection of a high-pressure manifold from a low-pressure pipeline to avoid the flowrate growth of working medium, are given. The automated virtual test bench based on the STAR-CD commercial software complex was created for development of an efficient construction. After consideration of several variants of the device construction, the best one was selected. Thermodynamic computation and experimental studies of the designed device were performed. A good agreement of numerical and experiment results is demonstrated. Refs. 6. Figs. 12.


To identify the trends in new flexibility markets, a set of market and aggregator platforms were selected and compared. The analyzed initiatives are relevant to consider alternative designs for European electricity markets. This review proposes a common methodology for analyzing these market models by comparing their description, market structure, market timing, and implementation. Furthermore, a range of policy implications and future research directions towards implementing these markets are presented. The results provide compelling evidence that the new market models represent a promising business with technical and economic justification, as they incentivize the uptake of flexibility from distributed resources by providing services to Distribution System Operators (DSOs) in coordination with Transmission System Operators (TSOs). Moreover, the interactions between these new market platforms and existing markets are of particular interest, and the contributions from aggregator platforms are also relevant to enhance the political vision of empowering the customers through their active participation in markets.


1. Green Energy for Sustainability and Energy Security.- 2. Exergy Analysis of Green Energy Systems.- 3. Wind Speed Distribution - A Theoretical Approach to Probability Density Function.- 4. Co-combustion and Gasification of Coal and Cattle Biomass: A Review of Research and Experimentation.- 5. Polymer Electrolyte Fuel Cell Modeling - A Pore-Scale Perspective.- 6. Nanostructured Hydrides for Solid State Hydrogen Storage for Vehicular Applications.


The purpose of this study is to investigate the Depaysement techniques in a new perspective, which are applicable to fashion window display. It was investigated by studying the case of Depaysement expressed in contemporary fashion window display. The analysis object of this study was limited to window displays shown at the world's most famous department stores in the last five years. The data was collected through related specialty publications and each department store's websites. The framework for analysis of this study is established by relevant precedent studies. The results of this study were drawn form comparative quantitative analysis from an ex-pert group. Through the study, the characteristics of Depaysement in the contemporary fashion window display were classified into 'Change of forms and materials', 'Heterogeneous combination of objects', 'Location change of an object', 'Conversion of recognition on an object' and 'Change of spatial awareness'. The expression approaches were 'Change of scale', 'Change of materials', 'Combination of heterogeneous objects', 'Heterogeneous combination', 'Arrangement of object in a strange space', 'Change of display method', 'Overlapped object', 'Paradoxical image', 'Variable awareness of boundary' and 'Reorganization of interior space and change of materials'.


This study divides and traces experience courses of families` disorganization and reorganization of North Korean refugees in North Korea, China, and South Korea after settlement respectively, from the course of their escaping North Korea to entering South Korea. Through these results, the study is to propose political implications. Main data for the study were analyzed through a case study as a qualitative study method, targeting eight people from July in 2012 to March in 2013. From the study result, though North Korean refugees seemed to disorganize and leave family relations in the course of escaping North Korea, it was found out that this is not disorganization but a preparatory stage which saves families standing at the crossroads of life and death and makes a chance to live with them someday. In these courses, in order for them to overcome their situations and survive, while repeating disorganization and reorganization of families, they used them as a way of saving themselves and their families. It was discovered that these phenomena always occurred simultaneously.


There are evidences of the increase in the consumption of anabolic steroids and the damages to health caused by their indiscriminate use, mainly among children and youngsters. The anabolic-androgenic steroids (AAS) consist in testosterone and its derivatives. They are produced endogenously in the testicles and adrenal cortex and are responsible for the secondary sexual characteristics associated to masculinity. Although the results of the exogenous use of AAS are still controversial, they have been used for the increase of physical strength and muscle mass. These substances are directly related to different clinical conditions such as: bladder cancer, coronary disease, gynecomastia, hepatic disorders and cancer, and sterility. This study aimed at approaching relevant topics related to the drugs action mechanisms, ways of use and metabolism, and side effects, besides the importance of the prevention in the use of those drugs in most diverse age groups. The abusive use of anabolic-androgenic steroids consists in a problem that has gradually occurred, which has given rise to laws, rules and support groups turned to the prevention, education and restriction of their use. Descriptors: Anabolic agents; Substance-related disorders; Androgenic steroids, Exercises Urival Magno Gomes Ferreira(1) Alan de Carvalho Dias Ferreira(2) Andréa Maria Pires Azevedo(2) Rafaella Lucena de Medeiros(3) Carlos Antonio Bruno da Silva(4)


The present invention relates to a method and system for determining the position of the mobile communication terminal in the mobile communication network. A method of locating a mobile communication terminal according to the present invention, the area where the mobile communication network covers is divided into a plurality of grids, the first base station signal information to the divided respective grid a step of collecting, and storing by storing in the database a first base station signal information the collected association with the position information of the grid, the second base station signal information the mobile terminal has received and measuring, a step of searching for location information by comparing the first base station signal information and the second base station signal information corresponding to the second base station signal information from the database, the retrieved position characterized in that it comprises a step of generating a final position information of the mobile communication terminal based on the information. .Field


The wheat gene Rht (Reduced height) which predeterminated the success of «Green revolution» and has been employed in creation of plant varieties with reduced stem elongation and resistant to stem lodging, encodes a protein containing highly conserved DELLA domain (J. Peng et al., 1999). Many other high-yield dwarf varieties also possess mutations in the genes coding DELLA proteins. Since the mutations did not affect viability and reproducibility of the plants the usage of the mutations for advanced plant breeding might be very promising (M. Ueguchi-Tanaka et al., 2007). Along with dwarfism, some mutations in the genes can lead to an opposite phenotype: to tall plants with spindly stems, the so called slender forms. What phenotype (dwarf or slender plant) would be developed depends on functionality of a protein region affected by the mutation. The paper considers in depth structure, posttranslational modifications, cellular localization and functions of DELLA proteins. The proteins being participants of complex protein-protein interactions play a role of repressors in gibberellin (GA) signal transduction. In the absence/or small concentration of GA DELLA proteins interact with specific transcriptional factor (TF) targets blocking their DNA binding activity and as a result restrain plant growth. In the presence of GA stem elongation is activated because this hormone promotes destabilization of DELLA proteins, releasing TF from their repression. Thus, restrained growth of the rht mutant as well as other naturally occurring dwarf plants is associated with accumulation of DELLA proteins in a result of their high stability. In turn, enhanced stability of the proteins can be caused by mutations in functionally important domains of either DELLA proteins or other players of GA signaling such as receptor GID1 and F-box proteins (GID2 in rice; SLY1 in Arabidopsis) of E3 ubiqutin protein ligase. They all participate in complex proteinprotein interaction which is necessary for DELLA protein degradation via 26S-proteasome pathway (B.C. Willige et al., 2007; K. Hirano et al., 2010). The paper reviews a role of different functional motifs of DELLA protein in transduction of GA signal: DELLA, TVHYNP, polySTV on N-terminal part of a molecule and С-terminal GRAS-domain, containing the motifs LR, VHIID, PFYRE and SAW. DELLAproteins possess no DNA-binding site. Most probably their repressive function is associated with GRASdomain via protein-protein interaction of LR region with target TFs (R. Zentella et al., 2007; K. Hirano et al., 2010). The polySTV domain plays a regulator role. Post-transcriptional modifications in the region are potentially able to change partners in protein-protein interaction and/or cellular localization of the DELLA proteins (M. Ueguchi-Tanaka et al., 2005; K. Hirano et al., 2010). A function of DELLA protein as an integrator of hormone signal ways and external factors is also discussed. In the context the DELLA proteins are considered as «correctors» of plant growth reaction depending on growth conditions (X.-H. Gao et al., 2011). Thus, the activity of DELLA proteins might underlie the plant phenotypic flexibility and promotes restrained plant growth under unfavorable environmental conditions.


High standards are required to succeed in the state upper secondary school system and many challenges have to be met. School principals with their leadership experience and practices are key actors to ensure the achievement of these goals. The study aims to find out Estonian state- operated upper secondary school principals' understandings of their leadership practices and supporting factors of their work. The data were collected with semi-structured interviews with eight school leaders. They were analysed with directed content analysis and leadership practices were analysed in four dimensions: setting directions; building relationships and developing people; developing the organisation to support desired practices; improving instructional programmes. An inductive approach was used to analyse data to explore the supporting factors. The findings showed that principals followed all dimensions of successful leadership practices. An important dimension appeared to be building relationships with students and teachers. The main concern in their work regarding school improvement challenges was teachers' workload. Principals saw the strength in having trustworthy and supporting relationships with the operator and being part of the state upper secondary school network. It would be recommended to systematically assess and develop the leadership competencies of school leaders along the dimensions of successful leadership and to closely address the professionalism and support of the school operator, because it was identified by school leaders as an important factor influencing their work.


In this issue, Editor Ayres gives previous editors an opportunity to muse about the discipline, the journal, and more specifically, the state of communication education, as part of a 50 anniversary celebration of Communication Education. A 50 birthday is a glorious occasion to reflect. For us, as humans, it means that more than half of our lives are likely past. What did we do? What counted? It also offers a chance to contemplate our future: How do we want to spend the time that remains? What should our legacy be? While CE 's life span will be longer than those of the contributors writing here, the same sorts of birthday reflections come to mind. Where has CE been and where should it go? With a strong and sustained belief that the future is bright for CE, I raise, in this article, seven issues that I hope scholars of the next fifty years will consider.


Coincidence imaging of radioactive isotopes using Compton cameras is proposed with time-of-flight (TOF) technique applied on image reconstruction. Target nuclides are those with cascade decay and a short metastable life. In this research K-43 has been used in simulation for coincidence imaging. The result shows a great improvement in image quality that results from the TOF information.


The Automated Manufacturing Research Facility (AMRF) is a unique engineering laboratory at the National Institute of Standards and Technology (NIST†) Center for Manufacturing Engineering. The facility provides a basic array of discrete metal parts manufacturing equipment and control systems – a testbed – that researchers from NIST, industrial firms, universities and other government agencies can use to experiment with new standards and to study new methods of measurement and quality control for automated factories. Construction of the facility began in late 1981 and the facility has been operating as a fully functional laboratory since late 1986, although improvements and equipment changes are continually ongoing. The project is funded by NIST and the Navy Manufacturing Technology Program and is significantly supported by industry through donations or loans of major components and through cooperative research programs. The goal of the project is to identify and exercise potential standard interfaces between existing and future components of small-batch manufacturing systems and to provide a laboratory for the development of factory-floor metrology in an automated environment, delivering proven measurement techniques to American industry. In addition, the AMRF is being used as a testbed for research on the next generation of "knowledge-based" manufacturing systems.


In the business environment, the process of organizational change is the need of time, then this need is the result of dynamic and continuous development that have business environment in the domestic economy as well as the modern global economy. Managing the organizational changes is very important process for organizational leadership. On one hand, the leadership constantly aims that the process of planning and implementing changes in the business environment have to be more effective in organization while on the other side, employee resistance during organizational change and the cost of change in the organization have be as minimal. The main objectives in this paper are as following: which are two main barriers in organizational change? Which is the key efficiency of organizational change? What effect they can have on change and how they can manage? Which are the main approaches that businesses should prepare for organizational change? How is reasonable the Kurt Lewin's model in organizational change, etc. In this research paper are identify different barriers that can appears during process of organizational change in business environment, such as: the first is power and in general the power is characterised as key elements in managerial achievement and as a main source of managerial efficiency in organizational change, then as similar barrier within the organisation change can be social force, it aims to use their social influence to stop or delay changes that affect them negatively in their interest; the second is described as mismanaging change models and approaches in modern business environment and some evidence shown that 60% of reported projects in organization change have failed, then theorists have argued that this model of change in business environment are inadequate in the current economy. DOI: 10.5901/ajis.2015.v4n3p83


Research proposes that economic policy uncertainty (EPU) leads to exchange rate fluctuations. Given that African countries experience higher levels of uncertainty in developed/emerging markets, we examine the extent to which domestic and foreign EPU affect exchange rates for a panel of 12 ECOWAS countries covering the period 1996–2018. In order to account for non-stationarity, cross-sectional dependence, and heterogeneity, the paper employs the dynamic heterogeneous panel approach. The ECOWAS has a dual currency arrangement ranging from a common currency union (CFA) to floating exchange rates (Non-CFA). To account for this, this study splits the sample data into CFA and Non-CFA areas. In addition, this study considers the role of the global financial crisis in the exchange rate-EPU nexus. Our results show that domestic EPU has a positive effect on exchange rates in the long run for Non-CFA areas. Different from the existing literature, our results suggest that domestic EPU does not explain exchange rate fluctuations in the short run. For all countries, foreign EPU leads to appreciation in the long run and depreciation in the short run. Interestingly, foreign EPU has a more dominant effect on exchange rate fluctuations in the selected countries than domestic EPU. This may reflect the weak institutional framework in these countries, which allows external fluctuations to have a greater impact. Moreover, this could be attributed to the increase in foreign capital flows during the sample period. Thus, these countries must develop effective policies to effectively absorb these external shocks. Results are robust to different proxies of EPU.


Sleep apnea is a prevalent and life-threatening problem, especially in infants. Napnea is a cost-effective neonatal (sleep) apnea detection system that aims to provide affordable alternative methods for continuous respiration monitoring and apnea detection. For infants diagnosed with sleep apnea, the current monitoring systems rely on sticky electrodes wired to a cardio-respiratory monitor or expensive smart devices. Napnea is a compact and affordable solution for apnea monitoring utilizing a soft, smart e-textile chest belt, integrated with a smartphone app.


Background: Metformin (MT) is a widely used oral anti-hyperglycemic agent for Type II diabetes. However, its role in protection against diabetic retinopathy is not clear. Aim of the work: The purpose of this study was to investigate the possible protective effect of MT on the diabetic retinopathy in rat model with special consideration on glial cell activation, neuronal apoptosis and neovascularization. Materials and Methods: Twenty-one male Sprague Dawly rats were divided into control group (n=7) and experimental group (n=14) that developed Type II diabetes by feeding on high fat diet for 8 weeks followed by repeated small doses streptozotocin injections. The experimental group were farther subdivided into Diabetic (DB) group (n=7) were left for another 8 weeks without treatment and MT group (n=7) were left 4 weeks then received MT for another 4 weeks. At the end of the experiment, blood and retinal samples were collected for biochemical, histological and immunohistochemical studies. Results: Metformin administration significantly decreased diabetic induced hyperglycemia and decreased the serum level of oxidative stress markers to the control level. Also, it significantly suppressed the diabetic induced increase of Glial Fibrillary Acidic Protein (GFAP) and Caspase3 expression. On the contrary, it enhanced the diabetic induced increase of vascular endothelial growth factor (VEGF) expression in the retina. Conclusion: This study indicated that MT may have an adjuvant role in prevention of diabetic retinopathy, and future studies are recommended to declare the regulatory mechanisms for its antiangiogenic or proangiogenic effects.


The removal of Escherichia coli from estuarine water was investigated. The survival of E. coli was dependent on the presence of protozoan predators and not on the presence of lytic bacteria. When indigenous protozoa were removed from estuarine water by filtration, the destruction of coliform populations was negligible. In studies designed to prevent the growth of indigenous bacterial populations without affecting protozoan populations, coliform destruction was significant.


This document contains the following papers on electronic portfolios from the SITE (Society for Information Technology & Teacher Education) 2001 conference: (1) "Portfolios: The Plan, the Purpose, a Preview" (Val Christensen and others); (2) "Electronic Portfolios (EP) : A How To Guide" (Jerry P. Galloway); (3) "Electronic Portfolios: A Glimpse into a Child's Education" (Claire Smith Hornung); (4) "Electronic Portfolios: Developed by Preservice Educators To Show Teaching Skills and Philosophies To Be Used by Future Employers" (Roger L. Olsen and David H. Dimond); (5) "Implementing Web-Based Electronic Assessment in a Graduate Instructional Technology Program" (Melissa E. Pierson and Michael Rapp) ; (6) "Electronic Portfolios: Technology Integration and the Preservice Teacher" (Beverly Ray and others); (7) "The Implementation and Integration of Web-Based Portfolios into the Proteach Program at the University of Florida" (Gail Ring); (8) "Easy Methods and Media for Creating Electronic CDROM Portfolios" (Desmond Rodney and others); (9) "Online Portfolios for Educational Technology Graduate Students: An Ongoing Capstone Project" (Jennifer L. V. Sparrow); (10) "The Impact of Electronic Portfolios on Early Experience Preservice Elementary Teachers in Integrating Technology into their Instructional Process" (Jane Strickland and others); (11) "Making the Case for Science Teacher Learning: An Analysis of Argument and Evidence in Electronic Portfolios" (Carla Zembal-Sual and Tom Dana); and (12) "A Pilot Project: Integrating Multimedia Portfolio Development into the Preservice Teacher Education at Randolph-Macon College" (Zizi Zhang). Most papers contain


This guide was created specifically for Dr. Leslie Jimenez's Organic Chemistry Lab, Fall 2014 Citing your work and avoiding plagiarism


Deficiency of ccystathionine may be a factor in the pathogenesis of the abnormalities in homocystinuria. Wong et al. [1968] showed that homocystinuric liver was able to synthesize cystathionine from homoserine and cysteine. Hence it may be possible to correct cystathionine deficiency in the brains of these patients.(1) Homoserine, (2) cysteine, (3) homoserine + cysteine (7.5 μ/g) was injected intraperitoneally to mice. It was observed that brain tissue could concentrate these amino acids. At 5 h after injection, brain cystathionine (μm/g) was significantly higher in groups (1), (2) and (3) than in controls (4). (1) 0.042±0.013, (2) 0.069±0.017, (3) 0.143±0.022, (4) 0.023±0.011 (n – 6).Ten groups of 25 weaning mice were fed with Purina Chow (PC) or PC + 5%, 2% or 1% of either homoserine or cysteine or both. Mice on diets containing 5% cysteine had initial weight loss and subsequent slow weight gain. These changes were correlated with poor intake. Light microscopy of organs was normal in all groups. Electronmicroscopy showed 'adaptive' changes in the liver of mice on diets with 2 to 5% cysteine. At 6 months, brain cystathionine (μm/g) in mice on homoserine was 0.018±0.005, 0.112+0.019, 0.054±0.007 and 0.040±0.003 respectively. The higher brain cystathionine in the experimental groups is signifacant.It appears that prolonged feeding of homoserine and cysteine in moderate amounts to homocystinurics is harmless and that cystathionine deficiency may be corrected. Clinical trials to assess the role of homoserine in the treatment of homocystinuria are now justified.


This paper examines the main variables related to the stay of battered women with aggressors. The different emotional responses in the victims are also analyzed according to the longitudinal course of domestic violence. Likewise, the maladapted coping strategies used by the victims to survive in this situation are described. The implications of this study for clinical practice and future research in this field are commented upon.


This work is concerned with the necessary conditions of optimality for a minimal time control problem $(P)$ for the linearized Navier-Stokes periodic flow in a 2D-channel, subject to a boundary input which acts on the transversal component of the velocity. The objective in this problem is the reaching of the laminar regime in a minimum time, as well as its preservation after this time. The determination of the necessary conditions of optimality relies on the analysis of intermediate minimal time control problems $(P_{k})$ for the Fourier modes $"k"$ associated to the Navier-Stokes equations and on the proof of the maximum principle for them. Also it is found that one can construct, on the basis of the optimal controllers of problems $(P_{k}),$ a small time called here \textit{quasi minimal} and a boundary controller which realizes the required objective in $% (P).$


A cell structure without a source/drain (S/D) could be very promising for scaled NAND flash memory beyond the sub-40-nm node, which utilizes the fringing electric field from control gates. In this work, we propose a new NAND string structure where cells have localized buried oxide layers (L-BOXs) and no S/D. The L-BOX is formed in the space between gates. When comparing the proposed cell string with the conventional cell string without the L-BOX, the former forms a field-induced layer more easily in the space, causing the threshold voltage in the space to decrease. Owing to not only the effect of the fringing field from the control gates (CGs) but also the additional effect due to the L-BOX, the proposed structure shows a wider threshold voltage window (ΔVth) and a higher bit-line current (Ibitline) during the read operation than the structure without the L-BOX when peak channel doping is uniform along the NAND string.


This brief presents a bidirectional asymmetrical multilevel inverter (MLI) that requires a single dc voltage source and low component count. Considering the weights assigned to the turns ratio involving the primary and multiple secondary windings of the transformer, as well as a proper switching logic, one can obtain an ac output voltage with up to 15 levels. The topology consists of a transformer, an H bridge on the primary side, and asymmetrical cells associated with bidirectional switches on the secondary side. Staircase modulation is employed to reduce the harmonic content of the output voltage, whereas a comprehensive analysis is derived. An experimental prototype rated at 1 kW is designed and implemented in the laboratory to validate the theoretical claims.


It is shown that the use of a small-signal real-frequency impedance or Q factor to calculate small-signal growth rates in an oscillator circuit is generally incorrect.


Refractive index effects are examined for transient cooling by radiation and conduction of a gray semitransparent layer. The layer is in a vacuum and so its heat loss is only by internal radiation leaving through its boundaries. Emission within the layer and energy reflected internally from its boundaries increase with the material refractive index. The reflected energy and heat conduction act to distribute energy across the layer and partially equalize the transient temperature distributions. For some conditions significant temperature gradients develop near the boundaries. The numerical solution method provides accurate transient temperature distributions in these regions so that the predicted radiative losses are not in error. An implicit finite difference procedure is used with nonuniform space and time increments. The integrals for the local radiative source in the energy equation are evaluated by Gaussian integration. a c D EI, N n q q,


Equipment maintenance management system is a new management model,to solve some questions of resources optimization scheduling during modern equipment synergetic maintenance,system requirement for maintenance was analyzed,and maintenance resources allocation algorithm using a modified Genetic Algorithm was discussed and the equipment maintenance management system was designed using modeling and simulation technology.


T I' HE Crab Orchard Basin is a submarginal area on which a _JL large experiment in land utilization and industrial development is being undertaken by the Federal Government. This project, having an area of approximately 31,000 acres, is situated on the north flank of the "Illinois Ozarks" in Williamson and Union Counties, most of it within the former county (Figures 1 and 2). The purpose of this study is to present a geographic survey of the project at the time of its acquisition by the Federal Government. Such a survey might be used for comparative purposes in the event of planned development of similar submarginal areas in Kentucky, Tennessee, and the Ozark region.


The constraint between the parachute and the small UAV is quite complicated, and it is difficult to accurately and quickly establish the dynamics model of the small UAV parachute recovery system. In order to solve this problem, a small UAV parachute recovery system is considered as a multibody system consisting of a parachute and a small UAV. The aerodynamic forces and moments of the parachute and the small UAV during the parachute recovery process are established respectively, and they are introduced into the center of mass of the parachute recovery system through virtual work. Then, based on Lagrangian equation, a six-degree-of-freedom dynamics model of the small UAV parachute recovery system is established. Finally, by comparing the simulation results with the experimental results, it is found that they are consistent, which verifies the accuracy of the model. The model established in this paper can provide some references for the formulation of recycling strategy and the parachute parameters selection for the small UAV parachute recovery system.


Sheet tensile specimens prepared from a cold rolled low alloy steel were annealed at 700°C to get equiaxed ferrite grains of 8, 21.5 and 32.5 μm diameters other than spheroidal carbides and inclusions, charged cathodically in 1 N NaOH and 0.1 N H 2 SO 4 solutions with a current density of 50 mA/cm 2 and tested in a hard beam tensile testing machine at a slow strain rate. Fracture characteristics were studied in SEM. By comparing the values of a at the point of intersection of computed σ vs. e and dσ/de vs. e curves with the actual values corresponding to UTS a measure of the enhancement of plastic instability by hydrogen was obtained. It has been found that the higher the hydrogen content the lower are the values of stress and strain at which plastic instability was initiated, and the higher the ferrite grain size the greater is the enhancement of this instability. These effects have been discussed in the light of viewed fracture modes.