A continuing study of the ingredients of Puerariae Radix, the roots of Pueraria lobata (WILLD.) OHWI, which is one of the most important crude drugs, has resulted in the first isolation of four new oleanene-type triterpene glycosides, named kudzusaponins SA1, SA2, SA3 and C1 (1-4). Their structures were determined to be 3-O-beta-D-galactopyranosyl-(1-->2)-beta-D-glucuronopyranosyl soyasapogenol A (1), 3-O-beta-galactopyranosyl-(1-->2)-beta-D-glucuronopyranosyl soyasapogenol A 22-O-alpha-L-arabinopyranoside (2), 3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-galactopyranosyl-(1-->2)-D- glucuronopyranosyl kudzusapogenol C 21-O-beta-D-glucopyranoside (4), respectively. The usefulness of tandem mass spectrometry in the structural determination of oleanene-type triterpene bisdesmosides is also discussed.


As changes in hard or soft oral tissues normally have a microbiological component, it is important to develop diagnostic techniques that support clinical evaluation, without destroying microbiological formation. The optical coherence tomography (OCT) represents an alternative to analyze tissues and microorganisms without the need for processing. This imaging technique could be defined as a fast, real-time, in situ, and non-destructive method. Thus, this study proposed the use of the OCT to visualize biofilm by Candida albicans in reline resins for removable prostheses. Three reline resins (Silagum-Comfort, Coe-Comfort, and Soft-Confort), with distinct characteristics related to water sorption and fungal inhibition were used. A total of 30 samples (10 for each resin group) were subjected to OCT scanning before and 96 h after inoculation with Candida albicans (URM 6547). The biofilm analysis was carried out through a 2D optical Callisto SD-OCT (930 nm) operated in the spectral domain. Then, the images were preprocessed using a [Formula: see text] Gaussian filter to remove the noise, and then Otsu binarization, allowing segmentation and pixel counting. The layer's biofilm formed was clearly defined and, indeed, its visualization is modified by water sorption of each material. Silagum-Comfort and Soft-Confort showed some similarities in the scattering of light between the clean and inoculated samples, in which, the latter samples presented higher values of light signal intensity. Coe-Comfort samples were the only ones that showed no differences between the clean or inoculated images. Therefore, the results of this study suggest that OCT is a viable technique to visualize the biofilm in reline materials. Because findings in the literature are still scarcely using the OCT technique to visualize biofilm in reline resins, further studies are encouraged. It should not contain any references or displayed equations.


With the rise of the otaku economy and WeChat mini-programs in the post-epidemic era, community group buying has entered a new stage. Many Internet companies have spared no efforts to invest in developing community group buying in an attempt to seize market traffic. When participating in community group buying, the head of the group purchase is gradually employed by enterprises. By virtue of the research methods including cyber-ethnography and in-depth interviews, this paper explores the operation mode of group buying platform and the employed status of the head of group buying in some communities of Xi'an, Shaanxi Province. On the one hand, the platform controls the labor of the heads through a hidden operation mechanism; On the other hand, the heads as the employees carry out emotional labor in different stages of labor while being involved in capital production. Meanwhile, they also present a struggle against platform operation and algorithm mechanisms.


High Performance Liquid Chromatography–Evaporative Light Scattering Detector was used for determination of the content of fructose,glucose,sucrose and maltose in gemmate wheat.The carbohydrates in the wheat germ were extracted with hot water and separated on Kromasil NH2 column of fructose,glucose and sucrose with satisfactory results and it was found to be simple,fast and accurate.


It is difficult to measure the random telegraph noises (RTN) of MOSFET subthreshold currents at the sub-pA level directly and accurately. In this work, we used a charge integration method similar to the operation of the CMOS image sensors (CIS) to characterize the RTN of subthreshold currents approximately from 1 fA to 1 nA, using a test chip of 1M cell array in a 40 nm process. We found that each RTN trap was active only within a specific window of gate voltages. The trap became less active or inactive outside the corresponding window of operations. We showed that the sets of RTN-active devices under different gate voltages were different. Furthermore, the choice of sampling frequency in measuring RTN and the number of sampled data points determined the observable range of RTN emission and capture time constants. For the data measured by sampling periods of 3.82 s, 299 ms, and 372 $\mu {\mathrm{ s}}$ , different sets of RTN traps were observed with different spans of time constants. The combined time constants range was about 7 orders of magnitude. For single-trap RTN, we found and verified a relation between the probability of trap occupancy (PTO) and the ratio of root-mean-square random noise (RN) versus the RTN amplitude.


Objective:To establish a simple five group classification method for patients with blood lipid disorder.Method: The serum TC, TG, HDL and LP(a)were detected in 587 normal lipid subjects and 921 abnormal lipid subjects. According to the lipids distribution, 921 abnormal subjects were classifed by simiple five group method. Result: Hypercholestrolemia, hypertriglyceridemia, low high density lipoidaemia, hyperlipoidaemia (a), mixed abnormal lipoidemia were accounted for 19.32 %, 28.66 %, 15.85 %, 18.02 % and 21.17 %, respectively. Female took the majority in hypercholestrolemia, while male was predominant in hyperlipoidaemia (a) and low high density lipoidaemia. Conclusion: This study reveals that this classification method is practical and feasible for the diagnosis and treatment of abnormal lipoidemia patients.


The aim of this paper is to analyze the Farsi-English statistical machine translation systems as a useful communication tool. Improvement of the nation's communication increases the need of easier way of translating between different languages in front of expensive human translators. In this work, a statistical phrase-based system is run on Farsi - English pair languages and the effect of its parameters on the translation quality has been deeply studied. Using BLEU as a metric of translation accuracy, the system achieves an improvement of 1.84%, relative to the baseline accuracy, which is increment from 16.97% to 18.81% in the best case.


As we enter the new millennium, business schools or economics faculties face a number of new challenges. The graduates of a business school are expected to be critical capable of 'learning to learn', technology-savy, and ethical. Mean while, the emergence of the internet as a new and powerful communication infrastructure has facilitated the rapid growth of the virtual business schools around globe. It leads to the global completion among processes, services, universies. As a consequence, Indonesian universies have to reform its products, processes, services, people, and environments. one of the 'best' approaches to do so is the adaptation of total quality management consep into higher education environment. This paper describes the profiles of future alumni of business schools, followed by a discussion on the emergence of virtual business schools as a new business education paradigm in the future. Finally, this paper tries to identify sereval factors critical to the successful implementation of total quality management in universities.


Foreign interventions and the involvement of non-state actors in elections, since their preparations and campaign period is a crucial issue, including in Indonesia, which has simultaneously held legislative and presidential elections on April 17, 2019. Investigations in US court regarding this case have further revealed the alleged Russian interventions through the use of propaganda method of firehose of falsehood with a successful implementation of a covert intelligence operation. The practice that brought about Trump's victory has alarmed Indonesian people on the possible similar practice in the country. This essay discussed the alleged Russia's interventions probably occurred in presidential elections in the United Sates and Indonesia. Applying a qualitative method, its data collecting was conducted with library researches. Its findings disclose that foreign interventions by using firehose falsehood propaganda method by widely and intensively spreading hoax in society also vulnerably occurred in Indonesia's election. Its implications could be serious, not only for the future of the country's democracy, but also for its political stability and national security as well as its post-election state unity. The author recommends state apparatus and civil society, in addition to the National Election Committee (KPU) and the Election Observer Body (Bawaslu), to immediately respond such kind of propaganda practice, so that they can take preventive actions and address the practice through consistent measures.


In the Cognitive Linguistics literature, the way viewers understand printed ads whose interpretation is based on
 metaphors and/or metonymies is conditioned by the principle whereby the source and target domains are called upon by the
 linguistic expression at roughly the same time (cf. Gibbs, 2006).
 Nonetheless, Herrero-Ruiz (2019) has shown how certain contextual
 effects are generated when one of the metaphoric/metonymic domains appears at a later stage in the interpretation process
 (direct vs. delayed domain appearance). In this paper, we shall describe various analytical
 patterns grounded in this new perspective as well as the specific interpretive routes that they imply. In doing so, we offer an
 alternative to the existing approaches that try to account for the possible interpretations printed ads based on metaphors and/or
 metonymies may elicit.


Posttranslational modifications of the microtubule cytoskeleton have emerged as key regulators of cellular functions, and their perturbations have been linked to a growing number of human pathologies. Tubulin glycylation modifies microtubules specifically in cilia and flagella, but its functional and mechanistic roles remain unclear. In this study, we generated a mouse model entirely lacking tubulin glycylation. Male mice were subfertile owing to aberrant beat patterns of their sperm flagella, which impeded the straight swimming of sperm cells. Using cryo-electron tomography, we showed that lack of glycylation caused abnormal conformations of the dynein arms within sperm axonemes, providing the structural basis for the observed dysfunction. Our findings reveal the importance of microtubule glycylation for controlled flagellar beating, directional sperm swimming, and male fertility. Copyright © 2021, American Association for the Advancement of Science. Year of publication 2020 Satish Bodakuntla, A S Jijumon, Carsten Janke, Maria M Magiera (2020 Nov 5) Purification of Tubulin with Controlled Posttranslational Modifications and Isotypes from Limited Sources by Polymerization-Depolymerization Cycles. Journal of visualized experiments : JoVE : DOI : 10.3791/61826


The utility model discloses a net rack support, which belongs to the technical field of net rack structure buildings, and comprises a support body and a mounting and fixing component, wherein the support body mainly includes a support ball, a support rib plate and a support bottom plate, and the mounting and fixing component mainly includes an embedded steel plate, an anchor bolt and a nut. A through hole is arranged on the support bottom plate; a rubber mat is arranged between the embedded steel plate and the support bottom plate; a support baffle plate is arranged on the embedded steel plate; a distance a is reserved between the support baffle plate and a lateral surface of the support bottom plate adjacent to the support baffle plate; the radius of the through hole is not smaller than the sum of the distance a and the radius of the anchor bolt; a nut pad is mounted between the through hole and the nut; the diameter of the cross section of the nut pad or the diameter of an inscribed circle of the nut pad is larger than that of the through hole; and the nut pad is provided with a through hole for the anchor bolt to penetrate through. The net rack support is used for solving the problems of economy and safety caused by excessive horizontal force bearing of a net rack support in a large-span net rack structure.


In the course of preparing this paper last year, the manuscript had been corrected several times. Regrettably when we sent it for publication in a hurry, one of unavailable manuscripts had been picked out. Our negligence unavoidably bring about following mistakes, viz. some specific names appeared in the Abstract not conformed with those in the decriptions and there more or less remained some errors in the descriptions. It stands to reason that it might be in time to correct the mistakes to republish this paper except the illustrations. All specific names being used in the present paper should be regarded as correct name for the valid publication.


This paper evaluates recent reviews of accounting research in Africa. These prompt consideration of nurturing research approaches encompassing diverse paradigms. Accounting research in highly ranked accounting journals has contained a small proportion of articles on Africa, predominately on larger, richer countries with developed capital markets. However, a gradual paradigm shift is apparent. About 51% of published African accounting research has employed qualitative methods unlike that on other developing countries, especially in Asia, where quantitative market-based research has been dominant. A gradual shift in African accounting research philosophies and methodologies has accompanied investigations of topics more pertinent to Africa, such as attaining Sustainable Development Goals. Significant numbers of African accounting articles in lesser or unranked English language journals, and in non-English language journals, especially in French, German, Portuguese, and Italian exist but fell outside the scope of this exercise. They need reviewing.


An erbium doped fluorozirconate fibre amplifier has been constructed which uses upconversion pumping at 801 nm to provide in excess of 20 dB small signal gain at a wavelength of 850 nm.


Lexical analysis [~lo 77} is concerned with scanning the input for significant clusters of characters called tokens. The input stream of characters is analyzed by using delimiters and a careful description of the way various types of tokens may be constructed. There are circumstances in which this approach is not sufficiently flexible. It may not be convenient to define the nature of tokens by giving a set of rules of construction.


The AMA manual on older drivers was created with the support of the National Highway Traffic Safety Administration (NHTSA) to address preventable injuries from motor vehicle accidents. Motor vehicle crashes are the number one cause of injury related deaths of people in the 65 to 74 age group. This is an exceedingly informative and useful compendium of this timely and complex subject. Although the manual addresses its remarks to physicians, other health care professionals should find it helpful. The first chapter contains facts and typical scenarios of patients who present themselves to the physician's office. The second chapter is about assessing risk which includes Red Flags for Medically Impaired Driving. It discusses acute events that may act as triggers, such as Traumatic Brain Injury, syncope, vertigo and surgery. Other triggers could be chronic conditions, family reports and, of course, medications that have the potential to impair driving. Here one can find a well-organized listing of obvious conditions that might impair driving such as stroke and visual impairments, as well as common medical conditions (heart disease) resulting from functional or structural abnormalities where driving impairment may be temporary. The chapter information is clearly outlined and easily transcribed to daily practice.


For many years galvanic zinc plating with hexavalent chromate passivation has been widely used as the primary means of surface finishing for fasteners. But environmental concerns have forced the industry to look for alternatives. In particular, the automotive industry has adopted zinc-rich and zinc alloy plating with trivalent chromate passivation as a substitute. But higher cost and greater coating thickness makes for a less-than-perfect replacement for traditional zinc plating technology. In this article, a nano-ceramic coating technology (NanoMate) on zinc-plated fasteners is introduced. In combination with trivalent chromate passivation, this nano-material technology can yield extremely high performance. It can even replace some of the fasteners from high-end materials such as stainless steel. We will also introduce a recent breakthrough process that brings zinc-plating to a new generation of fasteners that are totally free of chromate and heavy metal ions. A cost-effective, environmentally friendly coating system with excellent corrosion resistance properties has finally arrived. Galvanic zinc plating has long been the primary means of finishing fasteners due process simplicity, cost and excellent appearance. Adding hexavalent chromate passivation, also simple, cost effective and attractive, has the added benefit of excellent corrosion resistance. As the concentration of hexavalent chromate is increased to improve the corrosion resistance, the fastener color ranges from iridescent to olive and black. Table 1 compares he chromate concentration in the surface. The more hexavalent chromate, the better the corrosion resistance and the darker color.


This experimental study describes the spray structure of gasoline port fuel injectors by using PDPA(phase Doppler particle analyzer) and PMAS(particle motion analysis system). The macro characteristics of fuel spray such as the spray penetration, spray angle and breakup process were captured by PMAS and the micro characteristics of fuel spray such as droplet size and velocity were obtained by PDPA. New Pintle type and two-hole type injectors were used as gasoline port fuel injectors under various injection pressures. The correlation between SMD and injection pressure and between axial velocity and injection pressure will be discussed. And the comparison of breakup processes for the two types of injectors was also conducted. It is shown that new Pintle type injector has smaller droplet size than that of two-hole type injector.


The main purpose of this study is to clarify the basic but strong relationship between the circular economy and sustainability. By the increase in the world population, the globalization rate has increased and the global economy has grown rapidly. As a result, short-term economic policies focused on issues such as growth in economies, reducing unemployment and accelerating economic development, especially in the second half of the 20th century, have been given priority. However, as all of this was realized, criticism of the development economy began to increase, and the increase in population growth and industrialization, as well as the demand for natural resources and the pressure on these resources, highlighted the need for questioning about the continuity of global wealth and productionconsumption activities. At this point, instead of the economic evaluation of the continuity of the development of societies, a more comprehensive evaluation is carried out, which includes economic, social and environmental factors. The aim of this study is to enlighten the relation between circular economy and sustainability.


Group-velocity dispersion, third-order dispersion and propagation losses of 14m normal dispersion ZBLAN fiber are directly and continuously measured over 1500-2100nm range using all-fiber Mach-Zehnder interferometer. The fiber is then used for dispersion compensation at 2μm.


The authors present an exact analysis of framed ALOHA for the case of a finite number of users. This analysis, which is based on the use of a novel combinatorial technique, does not require any restrictive assumptions on channel traffic. This model can accommodate a general model for capture, in which the probability that one packet is received successfully depends on the number of packets involved in the collision. Performance results are presented for both uncontrolled and dynamically controlled systems. >


PURPOSE: To obtain the subject new antibody, especially preferably isotype IgG2a, capable of at least sufficiently neutralizing the cell-arresting/cell-injuring actions of TNFα and/or TNFβ, when bound to human cell having a TNF- receptor. CONSTITUTION: This monoclonal antibody against membrane proteins on human cells at least sufficiently neutralizes the cell-arresting/cell-injuring actions of TNFα and/or TNFβ, when bound to a human cell having a TNF-receptor. An antibody H398 having an ability for perfectly neutralizing the actions of the TNF is an immunoglobulin of isotype IgG2a, and is expressed by hybridoma cell system ECACC 90021617 (or H3987.6.1). COPYRIGHT: (C)1992,JPO


Palliative care is the best example of the art of nursing that looks at the circumstances and difficulties that cause suffering and affect the quality of life of patients. Palliative care is comprehensive care aimed at providing the necessary health care to patients with incurable diseases. A palliative approach is a completely holistic approach to another person, one of whom is a health professional and the other a patient. Palliative care interventions are aimed primarily at reducing suffering and pain which improves the quality of life of patients. The nurse is responsible for planning, conducting and evaluating health care with continuous assessment, educating patients and families, and collaborating with other members of the interdisciplinary team.


To increase industrial production, improve quality and meet consumers' demand, dairy industry has become more demanding regarding raw material suppliers. It is assumed that both milking type and raw milk sampling influence the physico-chemical composition and somatic cell count (SCC). To confirm this hypothesis, 180 samples from 30 cows were analysed. A factorial arrangement 2x3 was used, being two sampling types (manual - collecting the first 100mL, and milking machine - samples from the complete milking) and three types of samples (morning, afternoon and pool). The fat and TS (Total Solids) contents were most influenced either by the type of collection or the the type of sampling. Variation between the protein and lactose contents was observed according to the types of sampling. Statistical differences (P<0.05) were verified for SNF (Solids Non Fat) values according to the milking type. The SCC values showed low correlations to the contents of fat, milk and TS and negative correlations to the lactose and SNF contents. The results showed the influence of the milking type on the physical chemical composition and milk SCC and the importance of standardizing the milk sampling technique.


Amebiasis caused by Entamoeba histolytica parasite is among the worst gut diseases worldwide. The study involved detection of gut mycobiome signature of the infected subjects in a trial to improve ability to diagnose and treat this disease. The results indicated that diversity of samples slightly changed due to infection. Dendrogram indicated that the most common phyla in the human gut are Ascomycota, Basidiomycota and Zygomycota. Species Pichia kudriavzevii, Candida glabrata, Saccharomyces cerevisiae of phylum Ascomycota and Rhodotorula mucilaginosa of phylum Basidiomycota were found highly OTU abundant. Weighted unifrac diversity distances resulted in complete separation of the two groups. Differential abundance analysis indicated that four phyla, six families, nine genera and ten species showed considerable changes in gut mycobiome signatures within and among groups. Unclassified species of genus Malassezia (phylum Basidiomycota) showed high abundance in infected subjects as compared to healthy subjects, while families Saccharomycetaceae and Trichocomaceae, genus Saccharomyces and species S. cerevisiae showed opposite results. Linear discriminant analysis effect size (LEFSE) indicated that family Saccharomycetaceae, of which S. cerevisiae is a downstream taxon, can be a negative biomarker for amebiasis. In conclusion, the study provides new insights into possible use of Saccharomyces as a probiotic against amebiasis.


Making relative and absolute judgments of alternatives is compared. Relative judgments, following Saaty's procedure, require that each possible pair of conditions be compared. The subject indicates which member of the pair is preferred, then gives the magnitude of the preference on a 1–9 scale. The scores then are entered into a matrix and eigenvectors calculated for each subject in each condition. These eigenvectors then are evaluated in a conventional subjects × conditions analysis of variance. Two experiments are reported which show relative rating using eigenvectors is a more sensitive rating instrument than absolute rating. Experiment 1 compared discomfort glare for three simulated streetlight luminances. Experiment 2 evaluated the likability of various fonts when used on transparencies with two sizes of fonts (subtending.57 or.72°), two styles (bold and regular) and three types (executive, roman and sans serif). The relative rating method is a "more sensitive instrument." It has two disadvantages. One, it requires evaluation of all possible pairs of conditions by the same subject so the experiment itself may take longer. Second, the program to calculate the eigenvectors is not presently available in a standard statistical package such as SAS or SPSS.


The concise approach to enantiomerically pure, highly oxygenated carbobicyclic derivatives from sugar allyltins as well as the preparation of these sugar organometallics is reviewed.


Abstract The present article focuses on the dedicatory inscription of St Charalambos, the katholikon of the Lefkai monastery in the village of Avlonari in Euboea. The inscription dates back to the second building phase of the monument, between 1143-1180. Pantelis Zographos was the first researcher who dealt with the dedicatory inscription, making however fundamental mistakes. He was followed by Johannes Koder in 1973. All subsequent researchers adopted and followed Koder's interpretation. On the basis of new information, an amendment and new reading of the inscription are proposed which lead to a new marble carver's signature, that of Κοσμᾶς ὁ μαρμαράριος in the dedicatory inscription. Inscriptions with the name of a stone or marble carver from the Middle Byzantine period in Greece are, up to this point, extremely rare.


Hospital admission with alcoholic liver disease (ALD) has become increasingly common. Although there is a clear relationship between the risk of ALD and the dose of alcohol consumed, additional risk factors include genetic predisposition, gender, nutritional status, obesity, and co-existing liver diseases such as hepatitis C. ALD ranges from steatosis to alcoholic steatohepatitis and established cirrhosis. Several mechanisms are involved in the pathophysiology of ALD, including oxidative damage secondary to alcohol metabolism, and endotoxaemia leading to tumour necrosis factor α-mediated cell damage and death. Diagnosis requires a combination of a history of alcohol excess, clinical evidence of liver disease and compatible laboratory investigations, and the exclusion of other liver diseases. Liver biopsy may be necessary in cases of uncertainty. Presentation varies from incidental blood test abnormalities through to overt liver failure. The key to management is long-term abstinence and care should be delivered in conjunction with addiction services. Protein–calorie malnutrition is common and should be addressed along with specific thiamine replacement. Acute severe alcoholic hepatitis has a high mortality, and prognostic scores, such as the discriminant function and the Glasgow alcoholic hepatitis score, have been derived to identify those at highest risk and those who may derive short-term benefit from treatment with corticosteroids. Cirrhotic patients require hepatoma screening and variceal screening endoscopy. Liver transplant should be considered if the clinical condition does not improve despite a period of abstinence.


In this research, a CFT column connection with vertical plates is proposed, and studied through a finite element model. For this purpose, three-dimensional finite element models are constructed by a general purpose finite element code, ABAQUS. Comparing the results of the models indicated the effectiveness of the proposed vertical plate scheme in reducing story drift, increasing the shear strength of the panel zone.


: Storage tanks play a vital role in process industries. Controlling the level in storage tank improves and accelerates the process throughput. PID controllers are pressed into service for control purposes and furthermore to tune the controller PSO driven FA is used here. The system to be analysed is segregated into four sub regions and a dedicated PID controller is employed for each and every region. In the proposed work the PID based PSO driven FA is compared with the conventional method (ZN) with MATLAB and Simulink software. The obtained results are validated in the order of time domain specifications and performance indices such as rise time, peak time, Peak Overshoot, Settling time and ISE, IAE and ITAE respectively. The optimized results are obtained with less number of iterations and with considerably less errors.


Specialized methyl-CpG binding proteins (MBPs) have key biological roles during mammal development and can be classified into three structural families: the methyl-CpG binding domain (MBD) family, the zinc finger family and the SET and RING finger-associated (SRA) family. An enlightening Point-of-View article by Buck-Koehntop and Defossez discusses the recently resolved structure of two different proteins belonging to the zinc finger family, Kaiso and ZFP57, in complex with methylated DNA. The authors review the similarities within MBD proteins and suggest some commonalities in methyl-CpG recognition across the various MBP domains. Aberrant DNA methylation is a key player in the pathogenesis of chronic lympho-cytic leukemia (CLL). Whereas DNA hypomethylation has been shown to contribute to genomic instability in CLL, DNA hypermethylation and its impact in single gene silencing as well as the reversible nature of DNA methylation through inhibitor drugs have also been profusely reported. Therefore, the number of studies searching for aberrantly methylated genes that could potentially act as novel prog-nostic and treatment targets in CLL has been remarkable. Concomitantly, it is now recognized that different CLL prognostic subgroups are characterized by differential methylation profiles and that DNA meth-ylation outside of traditional CpG island promoters is also a fundamental player in the regulation of gene expression in CLL. A timely review by Cahill and Rosenquist now provides a comprehensive summary of the current literature within the epigen-etic field of CLL, highlighting some of the novel findings linking DNA methylation changes and CLL. Glioblastoma (GBM) is the most common and malignant type of primary brain tumor in adults and presents poor prognosis in most patients. However, a small percentage of patients show a long-term survival (36 mo or longer) after diagnosis. Because epigenetic profiles can provide molecular markers for patient prognosis, Shinawi et al. have now performed genome-wide DNA methylation profiling of short-term survivors (overall survival of less than 1 y) and long-term survivors (overall survival of more than 3 y) by quantitating meth-ylation at more than 480,000 CpG sites utilizing the HumanMethylation450K BeadChips. The study identified a set of CpG loci differentially hypermethylated between short-term and long-term survival cases, including members of the homeo-box gene family (HOXD8, HOXD13 and HOXC4), transcription factors NR2F2 and TFAP2A, and Dickkopf 2, a negative regulator of the Wnt/b-catenin signaling pathway. Metastable epialleles are mammalian genomic loci in which stochastic epi-genetic changes (such as DNA methyla-tion) occur before gastrulation and lead to systematic interindividual variation. Importantly, …


The Master-Disciple Relationship as a Metaphor for Healing in Jungian Psychoanalysis: Exploring Archetypal Transference Between Analyst and Patient by Zsolt Thomas Deak This study investigates the experiences of archetypal transference in Jungian psychoanalysis using a hermeneutically informed, qualitative method called intuitive inquiry. In archetypal transference, the transference does not emanate from a past personal experience, but relates to the collective unconscious; archetypal image or situation, which is projected on the analyst or patient. One of these possibilities that may appear in the analytic relationship is rooted in the archetype of the spiritual master-disciple relationship. The literature of Jungian psychology and spiritual traditions from around the world provide the background for this work. In the research study, 8 senior Jungian analysts have been interviewed, providing their own experiences with archetypal transference, about its relevance and effects on the therapeutic relationship. The interviews were audio-recorded, transcribed, and analyzed. In accordance with the procedures of intuitive inquiry synthesized and compared the data with the initial set of assumptions and statements. Through successive cycles of interpretation, the results were discussed and formulated into a theory by supporting the initial concept. Findings suggest that archetypal transference is inevitably present in the analytic relationship even if it is not evident or hard to distinguish from other transferences, and serves the psychological and spiritual growth of both the analyst and patient.


The oil supply system is a large part of the costs for a refrigeration chiller, manufacturing as well as operational. The system is bulky and expensive to manufacture and it might cause power los ...


Door frame with an elastic Corner sealing (2; 3; 4) for a door (5) consists of a stop profile with a head part (6) for a vertical push in front of it could end of the door leaf side of a door (5), characterized in that the elastic Corner sealing (2; 3; 4) an angle (to its head portion 6) has integrally formed thereon the end portion (7) which (in one of the end faces 8) of a closed door (5 supported) opposite surface of the door frame (1) is wider in the unloaded state, as a front-side door slot (9) and which has a stop surface (10) for a door edge (11) of a closing door (5) and is resiliently deformable by this, that the end part (7) with a closed door (5) over a large area abuts frontally thereto.


People exposed to parental divorce experience a number of relational and attitudinal effects. One such effect, the inter-generational transmission of divorce, involves a greater risk for divorce among those adult children whose parents were divorced. Social cognitive theory would explain many of the outcomes of parental divorce as inhibitory or disinhibitory effects learned through vicarious experience. Predictions from social cognitive theory were tested on a community-based sample of 821 adults. Results replicated the intergenerational transmission of divorce as well as higher family conflict, more negative attitudes toward marriage, greater likelihood of marriage to a previously divorced person, and a decreased likelihood of currently being in a close relationship as a function of parental divorce. Either family-of-origin conflict or negative marital attitudes mediated many of these effects. In other words, it is not parental divorce that is entirely responsible for certain relational and attitudinal effects.


In the article an attempt to identifi cation of modern football in the process of competitive activity in all its diversity from professional from professional sports management to intra football and by football segments of mass culture, in which fans are an integral and inseparable part of it. The authors consider sub-cultural phenomenon constructive support as a tool for positive infl uence of fans support on emulative results directly during a football match. In this case the set of identifi ed components of the sports process creates a new mechanism for its stakeholders


Objective:To observe the clinical effect of prednisone combine with vitamin B_1 and indomethecin in treatment of neuralgia following herpes zoster.Method:Nity-two cases with neuralgia following herpes zoster were divided into treatment group and control group at randomly.Forty-six patients in the treatment group were treated with prednisone 10 mg,three times daily,vitamin B1 10 mg,three times daily,indomethacin 25 mg,two times daily,for 15 days.Forty-six patients in the control group were treated with vitamin B1 10 mg,three times daily,and indomethacin 25 mg,two times daily,for 15 days.The visual analogue scale(VAS) was used to evaluate the therapeutic effects in the two groups.Result:The effective rate in the treatment group and control group were 86.96% and 60.87%,the therapeutic effects in the treatment group were statistically significant higher than that of the control group(字~2= 8.1176,P=0.0044).No marked side effects were observed in two groups.Conclusion:Our results showed that prednisone combine with vitamin B1 and indomethecin in treatment of neuralgia following herpes zoster are efficacy and safety.


Atmospheric structures due to gravity waves, turbulence, Kelvin Helmholtz instabilities, etc. in the mesosphere are being studied with a varying of ground-based and satellite-based instruments. At scales less than 100 km, they are mainly studied with airglow imagers, lidars, and radars. Typical radar observations have not been able to resolve spatial and temporal ambiguities due to the strength of radar echoes, the size of the system, and/or the nature of the atmospheric irregularities. In this work we observed spatially and temporally resolved structures of PMSE with unprecedented horizontal resolution, using the improved radar imaging accuracy of the Middle Atmosphere Alomar Radar System (MAARSY) with the aid of a multiple-input multiple output (MIMO) technique. The studies are performed in both the brightness of the mesospheric echoes and their Doppler velocities. The resolutions achieved are less than 1 km in the horizontal direction, less than 300m in altitude, and less than 1 minute in time, in an area of ~15km x 15km around 85km of altitude. We present a couple of wavelike monochromatic events, one drifting with the background neutral wind, and one propagating against the neutral wind. Horizontal wavelengths, periods, and vertical and temporal coverage of the events are described and discussed. A theory of stratified turbulence is employed in the present study. In particular, it is shown that the structure that propagates with the background wind is a large-scale turbulent KHI event.  Some important turbulence characteristics, such as a turbulent dissipation rate, buoyancy Reynolds number, and Froude number, support our conclusion.


Three isomeric 6-amino-3,6-dideoxyhexono-1,6-lactams of D- ribo ( 1a ), L- lyxo ( 2a ) and L- arabino ( 3a ) configuration were synthesized via the corresponding 6-azido-3,6-dideoxyhexoses starting from 1,2:5,6-di- O -isopropylidene-α-D-glucofuranose. Conformation of lactams 1a , 2a and 3a and their tri- O -acetyl derivatives 1b , 2b and 3b was studied using NMR spectroscopy. CD spectra of the lactams 1a - 3a , together with the D- xylo diastereoisomer 4a , were measured and interpreted according to semiempirical rules. NMR and CD measurements confirmed the chair conformation with an equatorial substituent on C-2 as prevailing for the all measured lactams.


Background: Ginkgo biloba extract is used in disorser of cerebral and peripheral blood circulation, dysfunction of brain, atherosclerosis etc., but there are little study about GbE in oriental medicine. We wished to assessthe efficacy of GbE for the treatment of cerebral infarction Method : The study group comprised 40 patients who arrived at hospital during 48 hours after attack. All patient were devided into two group. The control group was treated with Uhuangcheongsimhuan, Seonghyangjeonggisan, acupuncture therapy only, while the GbE group was treated with above therapy plus 5 days of administration of GbE(40mg three times per day). Result: 1. Symptom improve scores did not showed significant difference between control and GbE group. 2. Vasoreactivity of carotid siphon increased significantly in GbE group after treatment (in the left only : p


This paper considers and argues against old and recent readings of Hume according to which his account of moral judgement is non-cognitivist. In previous discussions of this topic, crucial metaethical distinctions—between sentimentalism and non-cognitivism and between psychological and semantic non-cognitivism—are often blurred. The paper aims to remedy this and argues that making the appropriate metaethical distinctions undermines alleged support for non-cognitivist interpretations of Hume. The paper focuses in particular on Hume's so-called 'motivation argument' and argues that it is a poor basis for non-cognitivist interpretations. While there is textual support for attributing to Hume what may be called 'modally weak' motivational internalism, there is no solid textual support for attributing to him either psychological or semantic non-cognitivism. The paper also challenges briefly some further alleged support for non-cognitivist interpretations. It concludes by offering some positive evidence against such interpretations, namely that Hume appears to hold that there are moral beliefs and moral knowledge.


Finally, it's looking safe for the U.S. to go back into space again. Next week, the U.S. will mark 32 months since the Challenger space shuttle disaster of Jan. 28, 1986. That watershed event halted most of the U.S. space program and forced re-evaluation and drastic revision of the whole U.S. space effort. But next week, if all goes well—after numerous and embarrassing delays and postponements, and frenetic hard work by thousands of engineers, scientists, and technicians—lift-off of space shuttle Discovery is slated to put U.S. astronauts back into space for four days. A two-day "flight readiness review" meeting at Kennedy Space Center in Florida last week unanimously agreed the shuttle is ready to fly next week. However, due to an approaching hurricane and other factors, at press time the National Aeronautics & Space Administration had not yet picked out the exact date for launch of mission STS-26 (Space Transportation System). (STS-25, the 25th shuttle ...


In an ideal distributed computing infrastructure, users would be able to use diverse distributed computing resources in a simple coherent way, with guaranteed security and efficient use of shared resources in accordance with the wishes of the owners of the resources. Our strategy for approaching this ideal is to first find the simplest structure within which these goals can plausibly be achieved. This structure, we find, is given by a particular recursive distributive lattice freely constructed from a presumed partially ordered set of all data in the infrastructure. Minor syntactic adjustments to the resulting algebra yields a simple language resembling a UNIX shell, a concept of execution and an interprocess protocol. Persons, organizations and servers within the system express their interests explicitly via a hierarchical currency. The currency provides a common framework for treating authentication, access control and resource sharing as economic problems while also introducing a new dimension for improving the infrastructure over time by designing system components which compete with each other to earn the currency. We explain these results, discuss experience with an implementation called egg and point out areas where more research is needed.


contact with the gas-liquid interface and being absorbed into the liquid phase. 2. When using the AVS with the baffle plate, the aerated water heights were lower. This improved the aerosol removal efficiency owing to reduction in the entrainment rate. Furthermore, the greater pool depth can be maintained than that for an AVS without a baffle plate, leading to an improvement in the efficiency of pool scrubbing. 3. The DFs of the wet-type pool scrubber for different initial pool water levels confirmed that the installation of the baffle plate improved the aerosol removal efficiency of the FCVS. 4. The DF of the wet scrubber using the AVS was showed several hundred times higher that that when using direct downward air injection of a large pipe.


Farming has been considered as main source of income for rural households in Nigeria, despite their involvement in other income generating activities. Focusing on income derivable from farming alone may be partially responsible for the ineffective poverty reduction strategies in Nigeria. Using the National Living Standard Survey data collected by the National Bureau of Statistics, this paper investigated the composition and determinants of non-farm incomes of rural households in Nigeria. The results show that the share of farm, non-farm wage (NFW)- and self-employment (NFS) incomes in total household incomes were 24.3%, 43.0% and 23.7% respectively. Households whose heads are male (0.647), had formal education (0.522), increased the likelihood of households' participation in NFW activities, while access to credit (-0.307) and having larger farm size (-0.221) decreased it. Access to credit (0.379); community participation (0.103); larger family size (0.193) and possession of capital assets (0.069) increased the likelihood of participation in NFS-employment activities, while having larger farm size (-0.211) decreased it. The study concludes that policy targeting poverty reduction should focus on providing enabling environment for poor households' access to non-farm activities in the study area.


The effect of oxide component content on the low melting point zone (simplified as LMP) in the CaO‐MnO‐Al2O3‐SiO2 system has been analysed by FactSage. The contents of [Si], [Mn], [O] and [Al] in liquid steel which are in equilibrium with the LMP inclusions in the CaO‐MnO‐Al2O3‐SiO2 system have been calculated. The results show that the CaO‐MnO‐Al2O3‐SiO2 system has the largest LMP zone (below 1400°C) when the Al2O3 content is 20% or the CaO content is 15%, and that the LMP zone becomes wider with increase in SiO2 and MnO contents (within the range of 0~25%). To obtain LMP inclusions (below 1400°C), [Si] and [Mn] can be controlled within a wide range, but [Al] and [O] must be controlled within the range of 0.5~5 ppm and 50~120 ppm, respectively.


Viruses are responsible for more than 50% of annual potato tuber yield losses and cause great economic damage. The traditional Croatian potato cultivar 'Brinjak' is important for local growers because of its economically profitable production and as a gene pool for future breeding programs. However, the full genetic potential of the cultivar cannot be exploited due to virus infection. In this study, we attempted to eliminate potato virus M (PVM) and potato virus S (PVS) from potato cultivar 'Brinjak' and to evaluate the effects on physiological parameters and yield. Shoot apices were isolated from PVM + PVS-infected sprouts and cultivated for six weeks on MS medium with the addition of 50 or 100 mg L−1 ribavirin. The surviving shoot apices were micropropagated. The in vitro post-eradication period lasted 200 days. DAS-ELISA and RT-PCR were performed on R0 and R1 plants 90 days after acclimatization to determine the sanitary status of the plants. Chlorophyll fluorescence and multispectral imaging were performed on the R0 plants at the same time. The success of PVS elimination was 33% at both ribavirin concentrations. However, neither concentration was successful in eliminating PVM. Plants with mixed infection (PVM + PVS) had more severe disease symptoms compared to PVM-infected plants, affecting photochemistry and multispectral parameters and, consequently, yield. PVM + PVS plants had significantly lower number and weight of tubers per plant and lower average tuber weight than plants with single PVM infection in most of the generations studied. The results indicate a strong negative impact of PVS in mixed infections with PVM and show the importance of its elimination from potato plants.


We show bubbles investigated with videography and multiple colour LED flash illumination. The short flashes show the propagation and development of the shape of the bubbles. The long flashes make the velocity vector of the bubbles directly visible and allow easy investigation of the unstable movement. If bubbles are used to reduce friction of ships, then it is effective to spread the gas volume over lots of micro bubbles. Another experiment is the investigation of the noise of a bass reflex loud-speaker. The visualisation of air flow shows linear behaviour at low power and a previously unknown effect at high power - continuous streaming of air in the bass reflex tube.


This paper deals with a low power operation of small hydro power plants. It is typical for small hydro power plants on small rivers without reservoirs where the power in low season is less than one-third of nominal power. That is why the efficiency is decreased. The generator has low efficiency in this operation due to constant no load losses. The analysis of losses is presented and possible improvements are suggested. The last part of this paper presents a simple method of reducing no load losses, calculation of the power savings and experimental validation of this method.


The use of normally on Silicon Carbide (SiC) JFET devices poses the question of safety and reliability in Voltage Fed Inverter (VFI) applications. Indeed, when a JFET is not driven with a sufficient negative voltage, the JFET is conducting and the VFI may be short-circuited. Therefore, it is needed to generate a negative voltage to turn-off the JFET to protect the VFI in case of gate driver failure. The settling time of this negative voltage must be inferior to the power system constant time to reduce the rise time of the short-circuit current. In this paper, a solution to protect the JFET and the system is proposed. A circuit description of an innovative topology using a Forward-Flyback topology with Primary Side Sensing (PSS) technique and an Output Voltage Estimation based on the Time Constant Matching (OVETCM) is presented. Moreover, the converter protects the VFI for an input range from 3 V to 610 V and up to 150 °C. Experimental results are provided and validate the design of the safety system.


Active scholars in the nanofluid field have continuously attempted to remove
the associated challenge of the stability of nanofluids via various approaches, such as functionalization
and adding a surfactant. After preparing a stable nanofluid, one must measure the properties,
as this is vital in the design of thermal systems.

Authors aimed to investigate the stability and viscosity of refrigeration lubrication oilbased
nanofluids containing functionalized MWCNTs. The effects of concentration and temperature
on viscosity were studied. Furthermore, the present study focused on the effect of sonication time on
the stability and viscosity of the prepared samples.

 After the preparation of chemically functionalized MWCNTs, solutions were dispersed
with an ultrasonic homogenizer for 2, 4 and 8 hours sonication at maximum power. Viscosity measurements
for all samples were made 10 minutes after sonication by adjusting the proper spinning
velocity using a digital rotary viscometer.

The first part deals with the stability of the nanofluid as a nanolubricant, and the second one
investigates the viscosity of the nanofluid and the effects of various parameters on it. The last one is
related to the validation of the measured viscosity values by means of well-known empirical correlations.
The measured data are given for validation issues.

The samples will have higher stability by increasing the time of sonication. The viscosity
of a nanofluid does not change with the increase of sonication time to two hours and higher. Up to
mass concentration of 0.1%, the effective viscosity increases with adding nanotubes linearly.


A young woman had diffuse follicular hamartoma that later in life was complicated by development of secondary follicular tumors (multiple proliferating trichilemmal cysts) and extensive inflammation leading to development of scarring alopecia. In addition, her palms and soles were involved by numerous discrete pits and punctate keratoses. Histologic changes of the palmoplantar lesions consisted of funnelshaped dilatation of the intra-epidermal and dermal portions of the eccrine sweat ducts. Dilated ducts were plugged with a columnar mass of parakeratotic material containing acid mucopolysaccharide and foci of calcification.


A previous study showed a survival benefit with maintenance therapy with pemetrexed in patients with advanced non‐small cell lung cancer (NSCLC). However, it remains unclear whether continuation maintenance therapy with pemetrexed is beneficial in Japanese patients. Here, we present our phase II study that assessed the efficacy and safety of cisplatin plus pemetrexed as induction chemotherapy, followed by maintenance therapy with pemetrexed in advanced NSCLC patients in Japan.


The level of natural radiation in some regions of Brazil, and the world, have become high. One of the places that have these high levels are underground mines. At these locations, the radiation may come from the ground, the walls, and the environment in the form of gases. The Group of Numerical Dosimetry (GDN), already developed, and utilizes various of Computational Models Exposure (MCE) to simulate situations where people are exposed to ionizing radiation. In one study, the GDN utilized the MCEs to to simulate the soil contamination by natural elements.This work aims to continue the study of contamination by natural elements, taking into account the energy interval range of gaseous natural elements. For this, the algorithm developed by GDN in 2004, was upgraded to simulate the irradiation of a person in the standing position, where its craniocaudal axis coincides with the axis of a cylinder circumscribing the body, where they emerge, isotropically, photonsThis update was done in the model MSTA (Mash Standard) To describe this situation we used a MCE composed of the font algorithm described by Vieira the phantom MASH and the MC code EGSnrcThe simulation results were organized in formats absorbed dose / air Kerma. These data may be used for other situations where the user that knows the energies, and their abundances, can interpolate the data to obtain new results without the need to conduct new simulations.


Findings of the seroprevalence survey conducted by Istat between May 25 and July 15 2020, on a sample of 64,660 people, show that only 2.5% of Italian people developed antibodies to SARS-CoV-2, a prevalence very far from the hypothesis of achieving herd immunity. Starting from the comment on these results, we summarized some of the main indicators used to evaluate the epidemic curves (R, R0, Rt) and the concept of herd immunity. R0, basic reproduction number, represents the average number of secondary cases we expect to observe from a single primary case in a population with no immunity to the disease before prevention and containment measures have been planned. Rt, effective reproduction number, is calculated over time and considers how the outbreak progresses, as a result of the containment measures and of people who might have gained immunity, because they survived from infection or were vaccinated. We presented the issue of herd immunity, or community immunity, a state of protection in a population obtained because the number of people in the population who are immune to infectious disease is above a critical threshold, resulting in a protection even for those who are not immune.


ABSTRACT Feminist political economy is not just about inequalities based on gender and sexuality. It reaches for new ways of thinking about individual agency and social structure, and challenges traditional definitions of exploitation and economic crisis. In this essay, a bit of intellectual history generates a rather optimistic vision of what could become a more creative, expansive, and pluralistic discipline.


In this study, an experimental work was carried out to measure the ultrasonic pulse velocity (UPV) of concrete having various water-binder ratios (w/b) and/or mineral admixtures including fly ash and blast-furnace slag at the laboratory. Moreover, a mock-up concrete wall was cast to investigate the evolution of UPV and the development of strength of in-situ concrete. Test results have shown that the UPV can be measured successfully before and after hardening of the concrete. The UPV curves expressed the behavior of concrete that were changing from a suspension to a solid structure during hardening process caused by the hydration of cementitious materials. Furthermore, these curves were also associated with the elastic properties and gave a comprehensive picture of the stiffening process. It is found that the hardening process and characteristics of concrete mixtures may be effectively investigated by monitoring of UPV. Consequently, ultrasound monitoring is promising for the quality control of concrete, particularly for in-situ concrete.


Two simple techniques are described for the design of recursive digital filters in the cascade configuration, which minimize the coefficient word-length. These are intended for cases where a statistical treatment is not valid because of the coarseness of quantization. The derivation of the discrete set of pole positions for the basic second-order section in the form of a z-plane pole grid is reviewed. This concept is fundamental to both techniques. They have been implemented by means of interactive operation on a small computer, but the more sophisticated technique, which is a form of one-at-a-time optimization, could be organized as a batchprocessed algorithm.


Introduction and purpose : The prescription of the serum protein profile is useful in the diagnostic orientation of certain immune, inflammatory and nutritional diseases. It is recommended by the senior health authority who defines the conditions. We study the conditions of this prescription by evaluating its relevance in the hospital services of Ibn Rochd University Hospital in Casablanca. Method : a descriptive and cross-sectional study conducted by a questionnaire containing 23 questions, 4 closed questions, 14 multiple-choice questions, 4 closed-ended questions and an open-ended question form 48 doctors. Results of the study : 81.8% of doctors have not been trained in serum protein profile and 72.9% have gaps in their knowledge of the protein profile. 55.7% of doctors say that biological advice is a great contribution. Conclusion : A relevant prescription requires a good enough training and complementarity between clinicians and biologist because of an accelerated diagnosis.


Abstract presented at the 30th International Conference of Alzheimer's Disease International, 15 18 April 2015, Perth, Australia Disciplines Medicine and Health Sciences | Social and Behavioral Sciences Publication Details Rahman, S., Swaffer, K., Gordon, P. & Manes, F. (2015). An analysis of 75 English language online articles on the 'G8 dementia summit'. 30th International Conference of Alzheimer's Disease International: Abstract Book (pp. 309-309). Australia: Alzheimer's Disease International. This conference paper is available at Research Online: http://ro.uow.edu.au/smhpapers/2865


Human CD1 is a family of thymocyte differentiation antigens which consist of heavy chains with mol. wts between 43 and 49 kd binding to beta 2 microglobulin. They are distant relatives of the major histocompatibility complex (MHC) class I and II products. Five human CD1 genes have been described. Three (CD1A, ‐B and ‐C) code for the serologically defined CD1a, ‐b and ‐c antigens. The protein products of the other two genes, CD1D and CD1E, remain unknown. All CD1 genes are located on chromosome 1 and hence are independent of the MHC locus. In this paper, the tight linkage of the CD1 genes has been established by pulse field gel electrophoresis, cosmid cloning and walking techniques. The 190 kb of DNA linking all five CD1 genes has been spanned by 14 overlapping cosmids. The order of the genes in the CD1 complex is CD1D‐CD1A‐CD1C‐CD1B‐CD1E, and, with the exception of CD1B, they are arranged in the same transcriptional orientation. The genes are evenly spaced in the complex except for the distance between CD1D and CD1A, which is two to three times greater than the average.


Bioactive substances are secondary metabolites that are produced by plants to protect their body; yet, such substances are able to control metabolic functions and have beneficial effects on the human body. Vitamins, minerals, phenolics, antioxidants,     flavonoids, carotenoids, and micronutrients and fiber appear to be responsible for beneficial health effects such as curing diabetics, cardiac ailments, etc. Fruit-extracted/isolated bioactive components are considered to have antioxidant, anti-inflammatory, antibacterial, cardioprotective, and neuroprotective activities, according to research data from a variety of in vitro and in vivo studies. As a result, fruits have the potential to be turned into medications and functional foods that may be used to avoid or alleviate a variety of chronic issues. The nutritional and phytochemical composition of fruits is determined by their maturation level, variety, environmental conditions, agricultural practices, and post-harvest handling and processing. This review aims to describe the importance of different fruits as a significant source of phytocompounds, which are being studied in clinical trials to create drugs for curing various human ailments, such as obesity, diabetes, cardiac, and cancer conditions. The vast and varied wealth of fruits may yet include undiscovered and extremely strong bioactive chemicals, which require more investigation.


A very detailed monitoring of a radio flare in the Seyfert I galaxy III Zw 2 with the VLA and the VLBA is presented. The relative astrometry in the VLBA observations was precise to a few muas. The spectral and spatial evolutions of the source are closely linked, and these observations allowed us to study a textbook example of a synchrotron self-absorbed jet in great detail. We observed a phase where the jet gets frustrated with neither expansion nor spectral evolution. Then the jet breaks free and starts to expand with apparent superluminal motion. This expansion is accompanied by a strong spectral evolution. The results are a good confirmation of synchrotron theory and equipartition for jets.


There are several researches have been conducted and different methods have been applied to extend the features of indoor location tracking using wireless devices. Fingerprint algorithm is one of the popular methods that have been used to track mobile nodes in indoor structure. This paper focuses on the enrichment of positioning accuracy of the Fingerprint algorithm. RSSI mechanism has been used on the Fingerprint Algorithm to encompass better performance for the accurate positioning. The paper has been proposed two different types of Fingerprint methods and their performance variants on different circumstances of indoor environment. The proposed Fingerprint Database mapping has been divided according to the RSSI data redundancy. The proposed Fingerprint methods has been successfully implemented and experimented on UTMMIMOS CoE lab. The experimented results of two Fingerprint methods has been analyzed and compared as well.


In consideration of the research requirements from rock mechanics at depth,the stress states of rock in deep-level projects is analyzed;and then the research topic of rock under coupled static and dynamic loads is brought forward.After exploration on multi-load drilling machine,INSTRON system and SHPB device,a new testing system is constructed,where rock specimen deforms and fails at medium to high strain rate.With the system,rock can be loaded with 0–200 MPa axial static pressure,0–200 MPa confining pressure and 0–500 MPa impact loading respectively or simultaneously.Tests for rock strength,fragmentation behavior and energy absorption with different coupling loads show that,with the same impact loading,rock strength is greater than its individual static or dynamic strength if the axial pressure is less than 70% of its static compression strength.With the same axial pressure,rock strength under coupling loads increases with the increase of impact loading owing to the strain rate effect.Under coupled static and dynamic loads,rock breaks with tensile failure mode.As for the particle-size distribution of fragments,the percentage of small particles increases with higher axial pressure or impact loading.The energy absorption ratio varies with coupling loads.With proper combination of static and dynamic loads,the maximum energy absorption ratio can be obtained.


ii DECLARATION iv ACKNOWLEDGEMENTS vi TABLE OF CONTENTS vii LIST OF TABLES xii LIST OF FIGURES xiii CHAPTER ONE 1 WASTE AND ITS TREATMENT 1 1.


The androgen‐dependent Dunning R3327‐H transplantable rat prostate adenocarcinoma model, in male Copenhagen rats, was utilized to examine dietary interventions on tumor growth and biomarkers. Diets were initiated 1 mo before tumor inoculation (20 mg of fresh tumor in Matrigel) and continued for ~18 wks. Rats showed similar food efficiency. Diets containing 10% broccoli (P <0.01), 10% of tomato and 10% broccoli (P <0.001), or following castration (P <0.001), had significantly reduced tumor weights compared to control tumors. A greater than 40% decrease in tumor weights was observed in the rats fed 10% broccoli, whereas a 52% decrease was seen in the 10% broccoli with 10% tomato combination group, and castration resulted in a 62% decrease. Those fed 10% tomato or the combination of 5% tomato and broccoli powders showed a trend for reduction in tumor weights, with an almost 30% decline in growth compared to the control (for both, P <0.06). The high lycopene diet (0.25 g of 5% lycopene beadlets/kg diet) did not significantly reduce tumor weight (P= 0.24). No physiologically relevant differences were seen in serum testosterone or dihydroxytestosterone concentrations. Blood and tissue samples were procured for assessment of biomarkers relevant to tumorigenesis using immunohistochemistry, gene expression via RT‐PCR, and P450 activity assays.


A BSTRACT . We discuss some properties of a model Hamiltonian for a system of three bosons interacting via zero-range forces in three dimensions. In order to avoid the well known instability phenomenon, we consider a regularized Hamiltonian with a repulsive three-body force. We review the main result recently obtained in [1] where, starting from a suitable quadratic form Q , the self-adjoint and bounded from below Hamiltonian H is constructed provided that the strength γ of the three-body repulsion is larger than a threshold parameter γ c . We also show that the threshold value γ c found in [1] is optimal, in the sense that the quadratic form Q is unbounded from below if γ < γ c . Finally, we give an alternative and much simpler proof of the result in [1] whenever γ > γ ′ c , with γ ′ c strictly larger than γ c .


UPON ligation of the cervix uteri in mice, and under appropriate conditions discussed elsewhere (1, 2), a sterile fluid accumulates within the uterus and may be aspirated at suitable intervals resulting in the production of 50 to 200 cc. of such fluid per mouse in the course of a year. It is postulated that this hydrouterine fluid represents accumulated endometrial secretions and the term UTERONE is proposed for this crude biologic material. Evidence supporting the assumption that uterone is secreted by the endometrium as well as preliminary data on its chemical composition have been published (1, 2). There is no information regarding biologic activities of endometrial secretions because no satisfactory methods have been available for the collection of these secretions (3). The data so far available and to be presented in this paper on biologic activities of murine uterone were all obtained with the crude material used either fresh or following lyophilization and preservation in the cold.


School education belongs to the category of service industry. Students are the significant sources of new ideas about teaching innovation. The paper has put forward three dimensions of students participating in teaching activities, analyzed the influence mechanism of student participation on teaching innovation, and disclosed the relationship between student participation and teaching innovation from the perspective of knowledge transfer.


This study was initiated by two research questions: 1) what are Korean-learning as an L2 students aware of about their L2 learning environments, and 2) how do they experience the L2 learning classrooms as their learning environments change. Therefore, this study was intended to investigate the case of German learners who started learning L2 abroad and continued learning L2 during the period of their student exchange program in Korea. Along with data analysis based on in-depth interviews, this study investigated inter-personal, physical, and psychological factors at play when participants experience the change from 'an KFL environment where Korean was a foreign language' to 'an KSL environment where Korean was native language'. In addition, those factors can reveal student reactions when they draw contrasts between their former and current learning environments, and evaluate the two environments. Participants attempted to adjust to the new environment in a way that maintained their own learning style, while also recognizing the difference between the environments. Furthermore, their new learning environment had effects on their motivation to learn, in terms of expansion, change, reduction, or elimination.


Chasmodon apterus Nees is a ground‐dwelling and important parasitoid of the frit fly in grassland. In 1985 and 1986, the new grass in the ploughed areas had more frit fly larvae and immature parasitoids than the unploughed permanent pasture grass. In 1985, the adults of C. apterus survived ploughing and other soil cultivation probably due to the single ploughing of that year. In 1986, double‐ploughing appeared to have reduced the number of C. apterus. It is therefore advised that methods which involve little or no soil cultivation should be utilized in sward improvement techniques.


The invention discloses an automobile door lock electric actuator comprising a box body, as well as a motor, a worm, a first transmission gear and a second transmission gear which are mounted in the box body, wherein a power output shaft of the motor is connected with the worm, the worm is meshed with the first transmission gear, the first transmission gear is meshed with the second transmission gear, a wiring terminal is further arranged on the box body, a conducting wire is led out of the wiring terminal, one end of the conducting wire is electrically connected with an external power supply, and the other end of the conducting wire is electrically connected with the motor. An internal circuit of the automobile door lock electric actuator adopts the conducting wire for connection; compared with the prior art, the wire can be arranged arbitrarily and not constrained by space, the production process steps are simultaneously reduced, the possible short-circuit phenomena caused by poor package and incomplete die cutting during the production process can be reduced, an the stability in product quality is improved.


As part of the great global movement of plants in the 18th and 19th centuries, many valuable and com- mercial plants were sent from the Neotropics to Europe as seeds or as live specimens. Cecropia (Urticaceae) was in cultivation in England in 1789, yet species delimitation was not well-understood until much later, long after subsequent introductions to other tropical regions where alien populations are now invasive. The earliest record of Cecropia being cultivated in Malesia is based on material of C. peltata thought to have been sent from the Royal Botanic Gardens Kew to 's Lands Plantentuin (Buitenzorg) in Jawa, Indonesia, sometime between 1862 and early 1868. In 1902, C. peltata was first cultivated in the botanical gardens of Singapore and introduced to Peninsular Malaysia in 1954. The source of these latter introductions is uncertain. Many researchers have assumed that C. peltata is the only species of Cecropia introduced in Indonesia, Malaysia and Singapore. We confirm that C. peltata is naturalised in Singapore and is invasive on the island of Jawa, Indonesia, and in Peninsular Malaysia. However, a second introduced species, C. pachystachya, has also been discovered as invasive in both Jawa and Singapore. There is no evidence for the third previously introduced species, C. palmata, being extant in Malesia.


The concept of a Lorentz force on screw dislocations, first introduced by Nabarro, is analyzed. It is concluded that the Nabarro-Lorentz force on screws and the Lorentz force of electromagnetism are not analogous, and that the term a Lorentz force on screws should be dropped in order to avoid confusion. Only when the screw is constrained to move on one slip plane is the analogy with electromagnetism complete. Total quasimomentum is not generally conserved when screw dislocations interact with elastic waves.


Managing the temperature of a nanosatellite is crucial to ensure the proper functioning of the payload and the platform during a mission. A thermal engineer faces the challenge of keeping both within acceptable temperature margins, which can be affected by various factors such as solar radiation, heat generated by on board equipments, and the spacecraft's orientation. To address this challenge, a simplified thermal model is typically created and examined. This model takes into account the spacecraft's geometry, material properties, and environmental factors to determine the temperature of critical components. This paper presents the results of simulations conducted on a 3D CubeSat orbiting at an altitude of 600Km. The simulations explore various PV panel combinations to determine the best compromise between thermal control and allowable power. This involves finding the optimal PV panel configuration that provides the necessary thermal control while still allowing the spacecraft to operate within its power constraints.


Hyperlipidemia is a significant risk factor for atherosclerosis and coronary heart disease (CHD). The aim of this study was to investigate hypolipidemic effects of Lactobacillus, Spirulina and their combination on Swiss albino mice fed a regular or high-cholesterol diet. Rosuvastatin was used as a reference drug The highest body weight, total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol LDL-C and the lowest high-density lipoprotein cholesterol were recorded in a positive control group (G5). Treatment with Lactobacillus or Spirulina or by their combination resulted in a significant decrease in body weight, TC, TG, LDL-C and significant increase in HDL-C (p < 0.05) in both mice fed a regular diet or high-cholesterol diet. The treatments induced a significant increase in Hb, MCHC and HCT levels in mice fed a regular diet (p < 0.05). They did not induce a significant effect on these parameters in mice fed a high-cholesterol diet, while treatment with standard rosuvastatin induced a significant decrease in these parameters (p < 0.05). The treatments induced a significant increase in the platelet count and WBC number in mice fed a regular diet p < 0.05), while they induced significant decrease in these parameters in mice fed a high-cholesterol diet p < 0.05. They also stimulated the innate immunity represented by both monocyte and neutrophil cells in mice fed a regular diet, while this immunity was reduced in mice fed a high-cholesterol diet. It also caused a marked reduction in inflammation and an improvement in the congestion of cardiac tissues, the aorta, and the spleen. The treatment of hyperlipidemic mice with combination of Lactobacillus and Spirulina gave similar results to those obtained with treatment by rosuvastatin.


The guava (Psidium guajava L.) belongs to the family Myrtaceae, it originates of Tropical America and it is distributed throughout the Brazilian territory. The production phase of the seedlings it is fundamental importance in the productive process, because seedlings better quality directly influence in success and final production. For this, it is made necessary to use substrates that meet the exigencies of the culture. In this way, the objective was to evaluate the germination of 'Cortibel' guava seeds and initial development of the plants in different substrates. The seeds were withdrawals of fruits guava physiologically ripe of the Cortibel cultivar, were then washed and air dried, next were planted in 1,5 L bags drilled, in September 2017 on two types of substrate (sand and commercial substrate Bioplant®) the sacks being kept in a screened nursery with 60% light interception. The design was completely randomized, with the substrates composing the treatments (washed sand and commercial substrate Bioplant®) and nine replications. Each replicate was formed by five bags totaling 45 experimental units for each treatment. In each perforated bag containing the treatments (substrates) were placed 5 seeds. Germination was accompanied along the throughout experimental period and at 129 days after sowing (DAS) was the period in which emergence of seedlings occurred. It was characteristics plant height, stem diameter and number of leaves were evaluated. The sand substrate provided a higher germination rate in relation to the Bioplant® substrate, however, the use of the Bioplant® commercial substrate presented higher initial development, with higher values of plant height and stem diameter, being the substrate indicated for the production of seedlings of guava 'Cortibel' by seeds.


In this article, a button antenna with a reflective frequency selective surface(FSS) is proposed to reduce its back radiation. The proposed antenna is low in profile, circularly polarized and designed for Wi-Fi and WLAN applications. The radiating element is made of copper sheet, while a transparent acrylic fibre sheet is used as a substrate. The antenna is fed by a coaxial line, and the FSS layer is designed onjeans material. The patch type FSS with split ring shape has also been designed to operate in the Wi-Fi and WLAN frequency band (5.250–5.S50 GHz) with the centre frequency of 5.51 GHz. The FSS reduces back radiation of the antenna by 4 dB. The antenna with FSS is fabricated, and a measured gain of 2. 9dBi is obtained that matches well with the theoretical value. The antenna is miniaturized by around 61.15% by the slits. To achieve circular polarization characteristic Defected Ground Structure (DGS) slots etched at the ground plane of the triangular patch. The measured impedance bandwidth is 190MHz, and the 3dB axialratio (AR) bandwidth is 160MHz, respectively.


Between two motherlands: nationality and emigration among the Greeks of Bulgaria, 1900–1949, by Theodora Dragostinova, Ithaca, NY, Cornell University Press, 2011, 304 pp., US$45.00 (hardcover), ISB...


Many plants are known for their phytotoxic potential. Such plants tend to suppress the germination and normal growth processes in other plants under their effect. Calotropis procera is one of the most dominant weed plants in Pakistan and is largely known for its insecticidal, pharmacological and phytotoxic properties. It is found abundantly around and inside the agricultural field crops. This study was aimed at investigating the allelepathic effects of C. procera on Triticum aestivm (wheat) which is one of the most important agricultural crops in most of the Asian countries. The allelopathic effects were gauged using different indices for germination behavior and seedling growth. Results indicated that C. procera leaf extracts has such allelopathic compounds which can significantly reduce the germination of and seedling vigor of Triticum aestivum.


Objective: To observe the nursing effect of method of integrated traditional Chinese and western medicine on acute mastitis in galactostasis stage.Methods: 63 cases with acute mastitis in galactostasis stage were divided into two groups randomly,32 cases in treatment group and 31 ones in control group.They were given to the same medical treatment and the same usual care.Then treatment group was given to hydropathic compress with traditional Chinese medicine,and control group with epsom salt.After 7 days the effects were observed.Results: In treatment group the cure rate was 43.75%,and the total effective rate was 90.63%.In control group the cure rate was 19.35%,and the total effective rate was 74.19%.There was significant difference between the two groups(P0.05).Conclusion: The effect of nursing method of integrated traditional Chinese and western medicine is better than that of western routine nursing method on acute mastitis in galactostasis stage.


This edition brings up to date the history of U.S. agencies for space exploration, the NACA and NASA, from 1915 through 1990. Early aviation and aeronautics research are described, with particular emphasis on the impact of the two world wars on aeronautics development and the postwar exploitation of those technologies. The reorganization and expansion of the NACA into NASA is described in detail as well as NASA's relationship with industry, the university system, and international space agencies such as the ESA. The dramatic space race of the 1950 and 1960s is recounted through a detailed histroy of the Gemini and Apollo programs and followed by a discussion of the many valuable social/scientific application of aeronautics technologies, many of which were realized through the launching of successful satellite projects. The further solar system explorations of the Voyager missions are described, as it the Challenger tragedy and the 1988 return to space of the Shuttle program. Future plans are outlined for a cooperatively funded international space station to foster the ongoing study of space science.


Sustainable Competitive Advantage defines the business and marketing strategies that have been selected by the organization with the aim of achieving long-term superior performance in the market place.

Keywords:

competitive advantage;
marketing;
strategy


Abstract Polyethylenimine-containing cotton fabrics were prepared by reaction of 1-epoxyethyl-3, 4-epoxycyclohexane with cotton fabric impregnated with polyethylenimine of a moderately high molecular weight. Fabrics with a high unremovable polyethylenimine content and with a different degree of cross-linking were obtained. Adsorption of several heavy metal salts such as mercuric chloride and cupric sulfate by the fabrics was investigated. Adsorption was controlled by polyethylenimine content of the fabric, extent of cross-linking, and the pH of the solution.


Fungal infection is one of the greatest problems facing storage of foods. Early in 1969, Christensen and Kaufman approved that seeds are subject for fungal contamination during storage which may destroy or at least devaluate them. Droby (2006) and Zhu (2006) estimated that about 20 up to 25% of fruits are damaged due to post-harvest handling and storage. Fungal infections of fruits may occur during growing, harvesting, handling, transport and storage (Bamidele et al., 2012). Furthermore, some of these fungi produce serious carcinogenic mycotoxins (Smith and Ross, 1991). One of these toxins is aflatoxins which are produced by certain species of Aspergillus like A. flavus and A. parasiticus (Palmgren and Ciegler, 1983; Samson and Frisvad, 1990; Trucksess et al., 2002). Accordingly, destruction of International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 5 Number 11 (2016) pp. 691-702 Journal homepage: http://www.ijcmas.com


The applicability of the financial penalties single on a criminal offense Illegal Fishing in the Fisheries court in Tanjungpinang years 2015 2017 cause problems its own in process of the execution conducted by The Prosecutor General (or in Indonesia Jaksa Penuntut Umum). Based on data obtained no inmates willing to pay fines has decided and only hope in the process of returning to the country of origin. The problem in this study is risk aversion criminal penalties against the perpetrator criminal offense Illegal Fishing in the Fisheries Tanjungpinang years 2015 2017. The research used in this study is the research in juridical normative empirical. The nature of the research used in this study is the descriptive analysis. The conclusion in this study, the criminal fines who decided over the last 3 years ineffective, after the defendant terminated with the criminal fines defendants cannot be executed, in a period of time that are not defined defendants returned to the state of origin without have serving time the slightest or returned to the country of origin without undergo any sanctions. Keywords—illegal fishing; criminal fines; criminal


During the 2014–2016 epidemic of Ebola Virus Disease (EVD), 28,600 people were infected and 11,300 died. The disease is spread by contact with the body fl uids of EVD patients as well as deceased victims. In contrast with previous epidemics, during the 2018 epidemic, EVD spread from isolated rural areas to densely populated cities in the Democratic Republic of the Congo (DRC). Complicating the 2018 epidemic is ongoing violence. According to Claude, Underschultz, and Hawkes (2018), an Ebola virus outbreak has not previously occurred in a war zone. Additional social


This article describes the role of language and literacy assessment in Response to Intervention, the assessment requirements and intent of RTI legislation, and the assessment principle in the International Reading Association's guiding principles on RTI. It outlines the multiple purposes of assessment required for a coherent RTI system, including screening, diagnostics, formative progress monitoring, benchmark progress monitoring, and summative outcome assessment. Building on this framework, the article then presents types of knowledge and skills teachers and specialists need in order to use assessments and their results effectively in an RTI approach to preventing language and literacy problems.


Objective
To evaluate the clinical efficacy of compound glycyrrhizin injection in the treatment of melasma.

Methods
A total of 30 melasma patients with blood vessel scores of ++ or +++ and melanin scores of ++ or +++, which were evaluated by dermoscopy and reflectance confocal microscopy (RCM) respectively, were collected from the Department of Dermatology of Hangzhou Third Hospital between May 2015 and July 2016. All the patients were randomly divided into 2 groups by drawing lots: treatment group treated with intravenous drips of compound glycyrrhizin injection at a dose of 40 ml once every three days for 8 sessions, oral vitamin C tablets at a dose of 0.2 g thrice a day, and oral vitamin E tablets at a dose of 0.1 g once a day, and control group treated with oral vitamin C and vitamin E tablets at the same dose as the treatment group. Three months after starting the treatment, the therapeutic effect was evaluated using melasma area and severity index (MASI) . Meanwhile, RCM, dermoscopy and VISIA skin detector were used to detect skin lesions, and the melanin score, blood vessel score and brown spot and erythema indices were calculated.

Results
For the treatment group, the melanin score and blood vessel score were both significantly decreased at 3 months after starting the treatment compared with those before the treatment (Z=2.773, 3.135, P= 0.006, 0.002, respectively) , so were the brown spot index (38.3 ± 3.1 vs. 43.9 ± 5.8, Z= 3.091, P= 0.002) and erythema index (26.5 ± 5.6 vs. 33.3 ± 7.7, t= 2.752, P= 0.010) . For the control group, the melanin score significantly decreased at 3 months after starting the treatment compared with those before the treatment (P= 0.023) , while no significant differences were observed in the blood vessel score or VISIA indices (P > 0.05) . Three months after starting the treatment, 9 cases showed marked improvement, and 6 showed improvement in the treatment group; 3 cases showed marked improvement, 11 improvement, and 1 showed no improvement in the control group. The therapeutic effect in the treatment group was significantly superior to that in the control group (Z= 2.276, P= 0.029) .

Conclusion
Compound glycyrrhizin injection is effective for the treatment of melasma, and RCM, dermoscopy and VISIA skin detector can be used to assist efficacy evaluation in melasma.

Key words:
Chloasma; Glycyrrhizic acid; Microscopy, confocal; Dermoscopy; Treatment outcome; Compound glycyrrhizin injection


The wavelet analysis represents the powerful instrument to extract information from a time series. It can be used to analyse time series that contain non-stationary power at many different frequencies. In the case of meteorological and climatological series, this type of analysis is particularly appreciated because it is able to extract important information from the signal. A conventional discrete wavelet analysis of signals was performed on the time series data of rainfall occurred in Sicily during last centuty, in order to eveluate trend, cycles and abrupt changes.


The LEAF (Learning from and Engaging with Assessment and Feedback) project addressed a key issue in third-level teaching and learning: assessment and feedback. The LEAF team comprised 18 academics from across the TU Dublin City Campus and representatives from all Colleges, along with the Director of Student Affairs and the Students' Union Education Officer. This paper presents the findings of the LEAF project. Assessment strategies have been shown to have a large impact on shaping student learning process strategies which feedforward into key employability skills. Learning from best practice, surveys from staff and students and analysis of the quality documents, the project developed a set of recommendations to enhance practices in assessment and feedback. Many challenges were identified over the course of this project in relation to the timeliness, amount and quality of feedback, assessment load, burden on staff and students, student expectations, monologue versus dialogue approach to feedback, inconsistency across programmes and poor integration of assessment and feedback into the academic quality framework. Key drivers identified throughout the project that are necessary to enhance assessment and feedback strategies include adequate resourcing, alignment of assessment with graduate attributes, inclusion of the student voice and more widespread use of technology.


Thermal stresses in chemical vapor deposited (CVD) vitreous silicate and phosphosilicate glass (PSG) films on Si substrates are measured in situ from room temperature (RT) to 900 °C. As‐deposited films grown at one atmospheric (APCVD) and lower pressures (LPCVD) are found to be inherently under a tensile and compressive stress at RT, respectively. On heating to 500 °C, the tensile component of the stress develops in both CVD films. Tensile stress increases with time at a given temperature. In the range 500–900 °C, the tensile component is reduced with temperature and time. During the cooling process from a temperature between 700 and 900 °C, the stress component of APCVD and LPCVD films changes from tension to compression. With APCVD film, the temperature dependence of the stress in the range RT–500 °C can be represented as a function of phosphorous concentration in mol % P2O5. Temperature and time dependence, and thermal hysteresis are attributable to water content, sintering, and viscoelastic properties...


Israeli security policy began to formulate in the early 1950s by its first leader, David Ben-Gurion. The three pillars of the defence doctrine were deterrence of possible threats; detection of impending attacks, and decisive military defeat of the enemy when the deterrence had failed. Up until the 1990s, the major perceived threat was an Arab military invasion into Israel and a war between states. In the early 1990s, Israel started to formulate a new security concept according to which the main threat might not emanate from states but from sub-state organizations such as Hamas and the Hezbollah. Israel is surrounded by non-state actors: Hamas, Hezbollah, rebel organizations in Syria, jihadist elements in the Golan Heights, Sinai and in Gaza, and the Palestinian Authority. Since the mid-2000s, a lot of attention is given to the Iranian nuclear threat and to rocket and missile attacks from Gaza, Lebanon and potentially other hostile areas.


Summary Background Renal artery stenosis is a common cause of secondary hypertension refractory to medical therapy. Percutaneous angioplasty along with metallic stent placement has been described as an effective treatment for revascularization of the renal artery. Case Report A 54-year-old woman affected by paranoid schizophrenia with a history of hypertension and chronic renal failure due to renal artery occlusion was treated by endovascular recanalization and stent placement that resulted in improvement of renal function and control of hypertension. Laboratory studies 4 months after the revascularization revealed blood creatinine decrease gradually from 8.57 mg/dL to 3 mg/dL. Conclusions Revascularization with stenting has proven to be a safe and effective procedure in the treatment of total renal artery occlusion which also led to a significant relief at a psychological level.


The invention discloses a label-free electrochemical immunosensor for melamine content determination, and a preparation method and application thereof. The immunosensor comprises a substrate electrode, wherein the surface of the substrate electrode is modified by a graphene-melamine-chitosan composite, and nonspecific active sites are sealed by bovine serum proteins. The method for preparing the electrochemical immunosensor is implemented by fixing melamine antigens on the surface of a glass carbon electrode with graphene/chitosan composite materials. Based on an immunoreactive competition mode, the electrochemical immunosensor monitors immune reaction through cyclic voltammetry and differential pulse voltammetry by taking K3Fe(CN)6 as a probe,, and can be used for melamine content detection. The immunosensor disclosed by the invention is high in sensitivity and specificity, simple in detection method and wide in application range; the limit of detection can reach 0.2 ng/ml, and the linear range is 5-1500 ng/ml; and the immunosensor has the characteristics of high speed, high efficiency, high sensitivity, good specificity, simple operation, low cost and the like.


The invention discloses a folding-and-unfolding switching driving mechanism for a spray-rod truss of a spray-rod-type sprayer, and belongs to agricultural machines.First swinging rods are hinged to the upper portions of the same sides of the outer end of a spray-rod-truss head-section welded part and the inner end of a spray-rod-truss middle-section welded part respectively; second swinging rods are hinged to the lower portions of the same sides of the inner end of a spray-rod-truss tail-section welded part and the outer end of the spray-rod-truss middle-section welded part respectively; a rocking rod is hinged to the side portion of the middle of the spray-rod-truss middle-section welded part; the inner end and the outer end of a first pushing-pulling driving rod assembly are hinged to a driving pin shaft and the first swinging rods on the spray-rod-truss head-section welded part respectively; the inner end and the outer end of a second pushing-pulling driving rod assembly are hinged to the first swinging rods and the rocking rod respectively; the inner end and the outer end of a third pushing-pulling driving rod assembly are hinged to the rocking rod and the second swinging rods respectively.The folding-and-unfolding switching driving mechanism is reasonable and simple in structure, balanced in operating movement, small in vibration, good in synchronicity, reliable in operation and wide in application range.


Public health advocates have repeatedly highlighted parallels between food marketing and childhood obesity. Yet existing literature has not explored the connection between the promotion of unhealthy foods and beverages, certain characteristics of integrated marketing communication (IMC) and the power of multinational food and beverage companies. This is problematic because IMC represents the dominant marketing paradigm in use today. This article draws on critical theory and literature from across public health, marketing, business and related fields. By focusing on macro-level antecedents and interactions, this discussion highlights a previously unarticulated dimension of the promotion of unhealthy foods and beverages to children and adolescents. In doing so, this discussion aims to generate greater recognition of the broader environmental circumstances and processes that surround food marketing tactics and their consequences for public health nutrition. This perspective will also contribute to an expanded understanding of unhealthy food marketing and its unintended consequences, among an audience of nutrition, public health and policy communities.