Background and Objectives: In routine life style various causes traumatic, inflammation, degenerative changes alters the biomechanics of cervical spine produce chronic neck pain, reduce the active ROM, reduce functional mobility and produce disability in neck. There for the present study aims to evaluate the effectiveness of HVLAT manipulation with muscle energy technique versus muscle energy technique alone in subjects with chronic neck pain as assessed by VAS, ROM, NDI and PSFS. Materials and Methods: A randomized controlled trial study was done and 120 subjects with diagnosis of chronic neck pain mean age 18-45 years both male and female were included in the study. Group A received HVLAT manipulation and Muscle Energy Technique and Group B received Muscle Energy Technique alone. The outcome was assessed in terms of Visual analog scale (VAS), active cervical ROM, Neck Disability Index (NDI) and Patient Specific Functional Scale (PSFS) at baseline and immediately post intervention.The intervention was given once and each session lasts for 15-30 minutes. Data was analyzed by Paired and Unpaired T Test, Wilcoxon signed rank test, Mann Whitney U Test. Results: Data analysis and results showed that both the groups demonstrated statistically significant improvements in pain, range of motion, reduction in disability scores and improvement in patient specific functions (P<0.05) following intervention. Conclusion: The combined therapy of HVLAT manipulation with Muscle Energy Techniques showed superior results as compared to the groups receiving Muscle Energy Techniques alone.


In this paper we present a filter sequential quadratic programming (SQP) algorithm for solving constrained optimization problems. This algorithm is based on the modified quadratic programming (QP) subproblem proposed by Burke and Han, and it can avoid the infeasibility of the QP subproblem at each iteration. Compared with other filter SQP algorithms, our algorithm does not require any restoration phase procedure which may spend a large amount of computation. We underline that global convergence is derived without assuming any constraint qualifications. Preliminary numerical results are reported.


2014 Experiments are reported on the switching characteristics of MISS devices incorporating a thin ( 50 Å) oxide layer, including the influence of a modulating base current, the effect of temperature and the dynamic performance. A quantitative analysis of a regenerative model of switching is briefly described and shown to give a good account of the experimental results. REVUE DE PHYSIQUE APPLIQUÉE TOME 13, DÉCEMBRE 1978,


The design of Oracle model can be formed a complete and clear center databank which can realize the unification and synchronization of data,and partly integrate system databank.It can be used to finish the comprehensive inquire about data outside,and harmonically finish the update of the whole data system inside,so that the system can be more integrality and punctuality,and reduce the work of administrators greatly.


It has been shown that injection of G-41 cell cultures, deficient as regards alkaline phosphatase and resistant to Coxsackie B3 virus, in conjunction with exposure to an alkaline phosphatase preparation from the calf intestine results in virus reproduction. Depending on the dose administered and multiplicity of infection there occur either complete destruction of the monolayer or death of some cells with the development of cytopathic changes specific for Coxackie virus.


A method for detecting the oxygen content in a measurement gas by means of at least one operating according to the Nernst principle concentration cell with an in communication with a measurement gas sensing electrode, with a standing with a reference gas volume in communication, connected to the measuring electrode via a solid electrolyte the reference electrode, between the reference electrode and the sensing electrode is preferably periodic pump current pulses are applied, characterized in that characterized reversed pulsed manner immediately after the end of each pumping current pulse the flow of current between the reference electrode and the measuring electrode in that one to the pumping current pulse reverse current flowing pulse predeterminable period between the reference electrode and the measuring electrode and a predeterminable current intensity (counter-current pulse) applies.


In photovoltaic power generation system,when the Boost converter is designed using a single-loop voltage mode control,it responses slowly and has poor stability.To solve the problem,a double-loop current mode control system was designed using UC3842,the internal current loop and external voltage loop as well.In order to improve the dynamic response speed and stability of the system,the internal current loop was compensated with slope,and then the open-loop transfer function of the system was discussed.According to its open-loop frequency characteristic,the external voltage loop was compensated with PI regulator.The test shows the experimental result is consistent with the theoretical analysis,and the design requirement is reached.


Marco Polo's Devisement du monde (Description of the world) is widely recognized as one of the most significant works of the European Middle Ages. It was the first account of travel into Asia composed by a layman in the vernacular, and the longest such account when it appeared. Polo spent more time in the East than any previously known European, his access to theMongol elite was unprecedented, and he provided a wealth of observations on Eastern peoples, customs, plants, animals, and many other phenomena. Polo's work is the first in Europe to mention Indonesia, Japan,Madagascar, Sri Lanka, and numerous cities in China and elsewhere and thereby represents an extraordinary contribution to Western geographical knowledge. The work's survival in 141 manuscripts and fragments in Latin and various European vernaculars, the wide range of patrons and owners of these books, and its early success in the print era all attest to the account's appeal. Its profound influence may be gauged too in the texts and maps produced throughout Europe that drew on or cited it as an authority in the late Middle Ages and well beyond and in the many abridgments, translations, and editions made of it in the centuries since. However, as scholars have long noted, Polo's account presents many authorial and textual problems. The text says that Polo dictated his account while in prison in Genoa in 1298 to a man generally identified as Rustichello da Pisa, but how exactly this process unfolded and how the text was transmitted thereafter remain vexed questions. It is moreover unclear to whom the narrative voice belongs in many passages, a lack of clarity that not only can be confusing but also undermines the text's claims to present the "pure truth" of what Polo himself saw or heard from trustworthy sources. There is also themajor question regardingwhich version of the text is most authoritative. There is no holograph or definitive urtext, and scholars are not sure which manuscript is the oldest. Pride of place is generally given to man-


Climatological features of the cloud variability on quasi‐2‐day (Q2D) and diurnal cycle (DC) timescales are investigated by utilizing the high‐resolution satellite infrared brightness temperature (IRBT) observations from January 1998 to December 2019. A distinct land‐sea contrast between the distributions of Q2D and DC signals is evident. Diurnally driven cloud activity mainly occurs over land and mountainous regions, and the Q2D timescale is more prominent over tropical ocean basins and land where organized convection is usually observed, for example, Congo and Amazon Rainforests, the United States and subtropical South America during warm seasons. The long‐term relationship between the Q2D variability and sea surface temperature (SST) shows that the clouds are more active on Q2D timescales over higher SST environments. The Q2D variability correlates well with both the Indian Ocean Dipole (IOD) and El Niño/Southern Oscillation (ENSO) from 1998 to 2019. The cloud variability associated with a range of convective available potential energy (CAPE) values is analyzed. The result over land shows that increased Q2D cloud variability emerges with higher CAPE, suggesting the coincidence of Q2D and organized convection, particularly given that this effect is strongest over regions with frequent mesoscale convective systems (MCSs) around the world. The cloud variability and the Q2D timescale analyses provide an alternative perspective to understand the global features of mesoscale convective systems. Overall, this study objectively examines the global variability of convective timescales related to the diurnal cycle and longer‐lived convective systems to provide a greater understanding of how the global convection population varies in space and time.


Abstract The establishment of a learning culture in schools is important for education to take place. The erosion of the learning culture which often culminated in the poor academic performance of Grade 12 learners in township secondary schools has been a cause for concern for many years. The Department of Education's countless efforts to rectify the situation have been to no avail. This article endeavours to establish the contribution that school principals can make towards resolving the problem. As manager and instructional leader of the school, the principal is in a suitable position to address this problem, and it is also his or her primary responsibility to lead and guide the school towards the attainment of good academic performance. The article discusses the principals' role in restoring a learning culture in township secondary schools. It discusses the management strategies or functions that principals can employ to restore a positive school culture. The management strategies were obtained by means of an interview from the principals of effective secondary schools. The literature study and the views of the principals obtained by means of a questionnaire confirm the effectiveness of the strategies in restoring a learning culture.


Training in oral and maxillofacial surgery (OMfs) in the UK and other european countries is unique, requiring degrees in both dentistry and medicine. This rewards trainees with a varied skillset but carries a financial burden that has been exacerbated by increasing tuition fees and the pay freeze for national health service (nhs) employees.1 although not a new concept, working through university is a necessity for many. however, work is often undertaken ad hoc or as a locum in dental or medical disciplines unrelated to omfs.


It is well known that Streptococcus pneumoniae remains a leading cause of childhood mortality; in 2008, it was estimated to be responsible for over 500,000 deaths in children aged 1–59 months.1 It is also known that the pneumococcus is a cause of significant morbidity and mortality among those younger and older than the 1- to 59-month age group,2,3 although prevention of disease in these age groups has not been the target of global efforts to date. Serious diseases caused by the pneumococcus across all age groups include pneumonia, meningitis and sepsis. Developing countries, mostly in Africa and Asia, carry the highest burden of both pneumococcal disease incidence and mortality in children; this burden is measured both in terms of rates and absolute numbers of cases and deaths.1


This chapter traces the evolution of the UK system of corporate governance through codes,and while doing so, exposes one of the main features which underpin its success story as a leading model for corporate governance worldwide. As will be seen, a paradox emerges: the UK system is constantly evolving in response to specific crisis on the one hand, while resisting the temptation to make continual changes to the Codes in order to raise the bar or go into greater detail on the other hand. Quite remarkably, the UK CGC has been successful in steering a middle course: continually resisting adoption of new policies «unless those policies also serve the primary objectives of the Codes, which is to improve the governance and stewardship of listed companies so that their owners can benefit from the long-term success of those companies». The chapter begins with looking at the term «corporate governance» and what it entails. It then looks at the historical background and emergence of the first code and the journey it has taken since in the last twenty two years. By the time the narrative arrives at present days, the picture that emerges is one of steady evolution, step by step, and of adapting to new realties in a speedy yet organised fashion, at times at the expense of a more rigorous and deep thinking. The unique formula that the UK has developed and has elevated is one of enigma: «adapt but not dramatically change».


The article discusses the problems of improving the functional quality of lamellar knives by such key indicators as cutting ability and blade resistance.


Ochratoxin A in dried vine fruits from Chinese markets Xiaoxu Zhang, Jingming Li, Nan Zong, Ziying Zhou & Liyan Ma a Center for Viticulture and Enology, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China b JinMaiLang Beverage Corporation Company Limited, Beijing 101500, China c Supervision & Testing Center for Agricultural Products Quality, Ministry of Agriculture, Beijing 100083, China Accepted author version posted online: 19 Nov 2013.Published online: 27 Jan 2014.


The influences of hot working parameters on mechanical properties of AZ80 alloy were studied by plane strain compression. The results show that tensile strength of AZ80 (T5) decreases with the increase of compression temperature. The tensile strength increases in proportion with the increase of deformation at 200 ~300 ℃,however tensile strength doesn't change when the equivalent strain is over 1.59 at 350~400℃. The largest tensile strength of AZ80 is over 1 times than that of cast alloy.


This paper reports a study on the teaching and learning processes in the course ARQ-342-T Theory of Architecture I at the Pontificia Universidad Catolica Madre y Maestra. The study focused on the students' transition from thought to form. This study stems from a personal concern that evolved in time, supported by documentation research and surveys among students, professors, and Department authorities. The study on teaching practice allowed the author to state that it is of paramount importance that teachers revise their own paradigms in order to transcend and to be coherent with their teaching practices.


This paper describes a 4.3‐mm radiometer and measurements made with it of the apparent temperature of various terrestrial materials, the attenuation through the atmosphere and the temperature of the sun. Materials whose apparent temperatures were measured included water, wood, metal, grass, asphalt, gravel and asbestos. Since their apparent temperatures are dependent upon their reflectivity, these data are interpreted in terms of the background reflected by the materials.The attenuation vertically through a clear sky ranged between 1.6 and 2.3 db. The sun, of optical disk size, was found to be between 104 and 1.2×104°K on May 3 and June 17, 1957.


The adsorption of 4-nitroanisole on silver colloidal nanoparticles was investigated by surface-enhanced Raman spectroscopy (SERS). Actually, the chemical binding with a metal substrate may play a role in changing the electronic structure of this molecule, which can be considered a push–pull chromophore, because an internal charge-transfer occurs between methoxy and nitrogroup. A SERS signal could be detected only in chloride-activated silver colloids, but the spectrum recorded with green-light excitation was not related to adsorbed 4-nitroanisole, but to its azoderivative, formed by photoreduction of the nitrogroup on the surface of the silver substrate. Copyright © 2013 John Wiley & Sons, Ltd.


Background  EMLA has a slow onset due to its limited percutaneous absorption into an intact skin, while Glycolic acid (GA) has been known to have the capability of disrupting the skin barrier function. To the best of our knowledge, the effect of 50% GA on the percutaneous absorption of EMLA has not been studied previously.


RNA editing is defined as the production of transcripts with RNA sequences different from those of the DNA template. Most of previous RNA editing studies have focused on organelles, while RNA editing of nuclear transcripts is largely unknown. Here, we describe the first example of nuclear transcript RNA editing in plant, the BOSS RNA editing regulates tomato flowering. The SNP (SNP1) located in the 5'UTR of BOSS gene (the Balancer of SP and SFT) is associated with tomato early flowering, and two transcripts of BOSS produced by SNP1 associated RNA editing show functional differentiation, where BOSS-β transcript promotes flowering while BOSS-α does not. Furthermore, these two transcripts of BOSS are shown to regulate SP (anti-florigen) pathway at transcription level in the shoot apical meristem (SAM). Our findings reveal a new layer of complexity in the control of plant stem cell proliferation and provide the evidence of RNA-editing of a single gene for flowering, suggesting that molecular breeding programs to increase the RNA-editing efficiency may improve the productivity of tomatoes and other agricultural organisms.


Actuator fault of a multicopter Unmanned Aerial Vehicle (UAV) may lead to a dangerous flight, and even damage the UAV. To ensure the flight safety in case of unpredictable actuator fault, many active fault tolerant control methods are studied in the last decade. An active fault tolerant method of a multicopter includes a fault detection, isolation and reconstruction (FDIR) scheme and a control allocation scheme. FDIR is of great importance for providing the estimation of the efficiency loss percentage. Previous FDIR procedures usually rely on an observer, which is complicated and computationally expensive. In this paper, we exploit the non-linear analytical redundancy techniques to provide a novel FDIR procedure, with a simple algorithm structure. We compare the isolation effectiveness and reconstruction performance of our approach and sliding mode observer based approach by a real experiment, respectively. It demonstrates that our approach shows a superiority of simpler algorithm structure and better fault reconstruction performance.


Abstract Finger millet (Eleusine coracana) is an orphan crop that has prominent nutritional traits such as high calcium. Biotechnological interventions in this crop suffer from constraints like genotypic dependency leading to inefficient regeneration and transformation systems. Biofortification requires improvements in the available plant tissue culture methods with major emphasis on underutilized crops like finger millet. Keeping this in view, the impact of inherent composition of phytonutrients (calcium, carbohydrates, proteins), phytochemicals (phenolics and flavonoids), and phytohormones (Abscisic Acid, ABA and Gibberellic Acid, GA3) on tissue culture responsiveness of four finger millet genotypes was studied. The study elucidated that the nutritional and phytochemical/hormone composition of seed/mature embryos as explants influence callus induction and regeneration on use of different phytohormones. There was significant (p < 0.05) callus induction at 1.5 mg/L 2, 4-D (2,4-Dichlorophenoxyacetic Acid) and 0.5 mg/L BAP (6-Benzylaminopurine) in all four genotypes. The high calcium variety GP-45 showed enhanced callusing and regeneration in comparison to other genotypes. Callus Induction Frequency and Shoot Regeneration Frequency exhibited significant positive correlation with calcium content and significant negative correlation with protein and flavonoid content for all the genotypes. The results demonstrate the importance of genotype selection based on inherent phytonutrient and phytohormone composition on tissue culture for crop improvement.


A proof is given of the measurability of the supremum norm on Wiener space. Classical Wiener measure is obtained by Gross [4] as a special case of his theorem on measurable norms on separable real Hilbert spaces. In this case the Hilbert space C' is the space of absolutely continuous functions on the unit interval which vanish at 0 and which have square integrable first derivative. The inner product of two such functions is the integral of the product of their derivatives and it is the supremum norm which is shown to be measurable. Gross uses his theorem on limits of measurable seminorms to prove this. However, since the definition of a measurable norm involves only the estimate of certain finite dimensional Lebesgue integrals, the short computational proof of this note may be of interest. The completion C of C' with the supremum norm is the space on which classical Wiener measure is defined. If lhi(s)l is the set of Haar functions normalized to be right continuous and to vanish at 1, then


This study aims to examine the scientific trend of approach and theme of lecturer's works of STAIN Bengkulu in the field of Islamic law (fiqh) and the scientific position of lecturer's works of STAIN Bengkulu as Muslim intellectuals. This article is using two approaches, namely the conceptual approach and historical approaches, whereas measures of research was conducted by reviewing documentation as primer data and interviewing as sekunder data. The results showed that the scientific trend of approach and theme of lecturer's works of STAIN Bengkulu was consists of three kinds: First, the normative trend of scientific approach and theme in Islamic law. This trend was categorized as "exclusive Muslim intellectualism". Second, this trend began to expand the discourse of study on fikih, but it was not to integrate with Western scientific approach. This trend was categorized as "inclusive Muslim intellectualism". Third, this study was more empirical and historical-sociological approach and theme in Islamic law (fikih) so that the discourse was more be able to answer the situation and condition of the people. This trend was categorized as "pluralist Muslim intellectualism".


Based on the relevant standards of China's natural water industry, this paper defines the concept and classification of natural drinking water, and divides each production link of natural drinking water industry. In addition, this paper also analyzes the pre-production link standards of natural drinking water from the aspects of investigation & exploration, monitoring & evaluation, comprehensive protection, and development & utilization of water resources separately, analyzes the in-production link standards in terms of packaging materials production, processing equipment manufacturing, product production & processing, and process quality control, analyzes the post-production link standards with regard to the inspection & testing, storage & logistics, allocation & distribution, and brand building, and points out the weak links of the standard system of natural drinking water industry, which is of great significance to the product quality improvement, inspection & supervision, and brand building of natural drinking water industry.


Colored-oxide glass filters containing CdS quantum dots were found to exhibit third-order optical nonlinearity in 1983. However, the dot sizes were somewhat large and the size distributions were wide. The sol-gel method proved to be a better alternative for CdS quantum dot materials. This paper describes the advantages of the sol-gel method, and how it has been exploited to prepare two types of CdS quantum dot materials. These are fully dense sodium borosilicate glasses and organically-modified silicates, Ormosils. Both materials give high values of third-order nonlinearity and excellent optical transparency.


Higher manganese silicide film (HMS, MnSix, x = 1.73–1.75) with addition of Si:B has been prepared on quartz substrate (SiO2) by magnetron sputtering of MnSi2 and Si:B (1 at.% B content) targets. It is found that the Si:B-added HMS film has a much lower electrical resistivity (R) but maintains its high Seebeck coefficient (S). As a result, the thermoelectric power factor, PF = S2/R, is greatly enhanced. It is also found that the metal In together with Ag-paste can be used as ohmic contact materials for measuring the electrical properties of the HMS film. The thermoelectric power factor can reach 1255 μW/m-K2 at 733 K for the Si:B-added HMS film, which is about two times higher than that of the pure HMS film.


We report on the noise properties of ion-irradiated YBa2Cu3O7 Josephson junctions. This work aims at investigating the linewidth of the Josephson oscillation with a detector response experiment at ≃132 GHz. Experimental results are compared with a simple analytical model based on the Likharev–Semenov equation and the de Gennes dirty limit approximation. We show that the main source of low-frequency fluctuations in these junctions is the broadband Johnson noise and that the excess 1 f noise contribution does not prevail in the temperature range of interest, as reported in some other types of high-Tc superconducting Josephson junctions. Finally, we discuss the interest of ion-irradiated junctions to implement frequency-tunable oscillators consisting of synchronized arrays of Josephson junctions.


Introduction: A current concern in the medical community is the rise in multi-drug resistant (MDR) organisms and their respective problems for children in developing countries. Children infected with such organisms need more care, hospitalization and expensive drugs for their therapy. So, an attempt was made to evaluate the multidrug resistant strains of Escherichia coli isolated from urinary tract infection in children from Jahrom to recognize the factors involved and control the use of antimicrobials in this area to select best strategies. Material and Methods: This cross-sectional descriptive study was performed on 90 E. coli strains isolated from the children aged from 1 month to 14 years, with urinary tract infection. The resistance patterns of the isolates to different antibiotics were determined by disk diffusion method. Results: In this study, the prevalence of the isolates demonstrating a multi-drug resistant phenotype was high. Seventy seven percent of the isolates were resistant to three or more antibiotics. The predominant pattern among these strains (14.4%) included resistance to ampicillin, cotrimoxazole and tetracycline which repeated among 13 strains. Conclusion: With due attention to the results and high rate of multi-drug resistance, regular monitoring of antimicrobial drug resistance in different areas is necessary to prevent the unsuitable consumption of the drugs leading to multi-drug resistance.


The immediate challenge of a sustainable environment requires more Teaching-Learning pedagogy catalyzing different types of learning.  The purpose of the present paper is to examine green school practices as a source for experiential learning in school. Green school practices, policies, initiatives, and integration of green school practices/activities in the school curriculum are analyzed.  The outcome of study discloses that environmental education is important subject matter in science and social science. The environmental-related facilities/resources/activities are now emphasized as a significant tool for Teaching-Learning. To combat climate change and create awareness on the environment among students, teachers require an orientation program for the integration of Green School Practices/activities/ resources in the school curriculum.


The aim of this work was to evaluate the effects of different concentrations of K and B foliar application on fruit quality parameters of pomegranate fruit (Punica granatum). To achieve this objective, in 2007 a trial was carried out in a pomegranate orchard located in Ferdows region, Iran. The plants were sprayed with three K (0, 1.5, and 3 gㆍL?¹ potassium metalosate) and three B (0, 1.5, and 3 gㆍL?¹ H3BO3) concentrations, in a complete randomized design with three replications; spraying was replicated three times during fruit development stage. Foliar application of K and B significantly increased the content of K and B in the leaf (P ≤ 0.01), and peel and juice of fruit (P ≤ 0.05). The fruits of trees fertilized at the highest K concentration had higher titratable acidity and total soluble solids than those in the other treatments. Foliar K application at 1.5 and 3 gㆍL?¹ significantly (P ≤ 0.05) increased the content of anthocyanins, phenolic compounds, and antioxidant activity of fruit juice. Application of K at 3 gㆍL?¹ alone decreased the fruit firmness significantly, while the spraying of B at 3 gㆍL?¹ increased the fruit firmness significantly. Content of ascorbic acid increased significantly with increasing of K concentrations and the highest content of ascorbic acid observed in the treatment of combination of K and B at high concentration. Foliar B application significantly (P ≤ 0.05) increased the peel percentage of fruits, while it decreased significantly (P ≤ 0.05) the juice percentage. K application at 3 gㆍL?¹ alone and with combination of B applications showed the highest significant content of total sugar content. Electrolyte leakage of fruit peel decreased significantly (P ≤ 0.05) by foliar K application compared with no K fertilizer application.


The economic status of American Indians is substantially worse than that of the general population in the United States. For example, per-capita incomes are 40 percent below national averages (Leichenko, 2003), and large numbers of American Indians have earnings in the lower end of the income distribution (Gregory et al., 1997). These economic hardships are also reflected in the lower average incomes in counties with a high proportion of American Indians (Leichenko, 2003, Table 2). These economic hardships are correlated with a slew of negative consequences including food insecurity, food insecurity with hunger, high rates of obesity, high prevalences of diabetes, high rates of tooth decay, and low rates of breastfeeding. For example, one-in-five American Indians were food insecure in 2003 in comparison to about one-in-eight for the entire population and the rates of food insecurity with hunger were twice as high for American Indians (Gundersen, 2006). Current efforts to address these negative consequences associated with these resource-constrained food problems include several food assistance programs. The focus of this paper is on the Food Stamp Program. In 2003, 23.9 million low-income Americans received food stamps resulting in 24.6 billion dollars in benefits. Given the high poverty rates among American Indians, a large proportion of American Indians would be eligible for food stamps and presumably would benefit from their receipt. In light of the importance of food stamps, understanding the food stamp usage by American Indians viz. the general population seems relevant. This paper represents the first examination of food stamp use among American Indians at the national level. We first consider how the participation rates among American Indians in the Food Stamp Program compares to the general population? To do so, we use data from the 2 1989 to 2004 March Supplements of the Current Population Survey (CPS). We establish the food stamp participation rate (i.e., the number of food stamp households divided by the number of eligible households) for each of these years. The use of multiple years allows us to ascertain how the participation rate may have changed over time. The CPS has been used extensively in other research on the Food Stamp Program. We next consider whether, after controlling for other factors, if American Indians have higher rates food stamp participation than the rest of the population. Given the serious economic challenges facing many American Indians, we would expect higher participation rates among American Indians in comparison …


This essay uses saints' lives and miracle stories to demonstrate the various ways that religiously affiliated women managed for a socially marginalized population the daily experience of health and illness. In this essay I explore how people came to believe in a saint's ability to heal, how they adapted their feelings and intentions to affective models provided by her vita and miracles, and how they recounted their experiences of this adaptation in stories of bodily healing. I argue that, by examining the healing community that sick petitioners formed around female saints, we might come to recognize whole new categories of health on which medieval medical resources were premised. Furthermore, as scholars of religion, we may better understand the affective and devotional mechanisms through which the sick and indigent came to experience relief.


Searching and mining large graphs today is critical to a variety of application domains, ranging from community detection in social networks, to de novo genome sequence assembly. Scalable processing of large graphs requires careful partitioning and distribution of graphs across clusters. In this paper, we investigate the problem of managing large-scale graphs in clusters and study access characteristics of local graph queries such as breadth-first search, random walk, and SPARQL queries, which are popular in real applications. These queries exhibit strong access locality, and therefore require specific data partitioning strategies. In this work, we propose a Self Evolving Distributed Graph Management Environment (Sedge), to minimize inter-machine communication during graph query processing in multiple machines. In order to improve query response time and throughput, Sedge introduces a two-level partition management architecture with complimentary primary partitions and dynamic secondary partitions. These two kinds of partitions are able to adapt in real time to changes in query workload. (Sedge) also includes a set of workload analyzing algorithms whose time complexity is linear or sublinear to graph size. Empirical results show that it significantly improves distributed graph processing on today's commodity clusters.


Introduction:
 The inflammasome and the downstream pro-inflammatory cytokine interleukin-1ß (IL-1ß) have emerged as critical modulators of atherosclerosis and acute coronary syndromes (ACS). It therefore represents an important therapeutic target to treat coronary artery disease. This study investigates the activation of the inflammasome in circulating monocytes of ACS patients, and the effectiveness of SMW139- a compound selected from a panel of over 70 novel P2X7 antagonists based upon its excellent pharmacokinetic properties- on modulating the downstream inflammatory signalling pathway.

 Hypothesis:
 The P2X7 antagonist SMW139 reduces inflammasome activation.

 Methods:
 In vitro:
 THP-1 monocytic cells were treated with interferon-
 γ
 and lipopolysaccharide for 3 hours, then pre-incubated with SMW139 (1-1000nM), prior to ATP stimulation to activate the inflammasome, and collection of supernatant for IL-1ß measurement.
 Ex vivo:
 Peripheral blood mononuclear cells (PBMCs) were collected from 19 STEMI patients at time of infarct, and 3 healthy controls. Monocytes were pre-incubated with SMW139 or DMSO control prior to ATP stimulation. IL-1ß and caspase-1 activity were measured by ELISA and fluorometric assay.

 Results:
 In vitro:
 Sigmoidal dose-response curve demonstrated a LogEC50 of -8.069±0.16.
 Ex vivo:
 High levels of detectable P2X7 expression in PBMCs was confirmed by flow cytometry. Baseline levels of secreted IL-1ß were significantly elevated in PBMCs from STEMI patients compared with healthy controls (STEMI: 8.2±0.6, Control: 4.2±0.1;p=0.02). There was a significant increase in IL-1ß secretion post ATP-induced inflammasome activation in STEMI PBMCs (53.8±9.4;p<0.0001) but not control (9.8±0.9). P2X7 inhibition significantly attenuated this ATP-induced IL-1ß secretion in STEMI cells (13.9±2.4;p<0.0001) but had no effect in controls (7.5±2.8). Similarly, P2X7 inhibition resulted in approximately 60% reduction of ATP-induced caspase-1 activity in STEMI cells (p=0.01).

 Conclusions:
 The P2X7 antagonist compound SMW139 effectively inhibits the inflammasome, causing a significant reduction in caspase-1 activity and IL-1ß cytokine levels, and holds promise as a novel therapy for patients with atherosclerosis and ACS.


The present paper embodies the results of a survey conducted on oribatid mites inhabiting coconut palm cultivated in and around the Calicut University Campus of Malappuram District, Kerala, South India. The survey revealed the occurrence of a number of oribatid mites belonging to several genera, mainly on the foliage. Among the different species collected, one new species of Uracrobates is described. The genus Uracrobates is being reported for the first time from India.


On the, Changes in he Composition and Properties of the Milk in the Human Female, produced by Menstruation and Preg  nancy; also, on the Food most Proper for Infants when deprived of the Milk of the Mother


Women are more active as economic agents in Africa than anywhere else in the world and perform the majority of agricultural activities in some countries. Societal norms, beliefs and economic constraints limits their access to agricultural productive resources, decision making process and adoption of climate smart practices(CSPs). This paper documented the effect of gender gaps on adoption of CSPs in Nigeria. Primary data were collected through a structured questionnaire using a multistage random technique from a cross section of 1,747 rice and maize farmers in Nigeria. Data were analyzed using descriptive statistics abbreviated women empowerment in agriculture index (AWEAI) and Multivariate Probit regression. The AWEAI results showed that men are more empowered than women in four indicators out of the six indicators of empowerment except for use of credit (37%) and workload (68%). The adoption of CSPs revealed that female farmers adopted agroforestry more in the derived savannah (78%), northern guinea savannah (79%) and rain forest (64%) while Male farmers generally adopted crop rotation (28%) in derived and zero tillage (52%) in northern guinea savannah. The Multivariate probit results indicated that female plot managers have higher probability of adopting green manure(p<0.05) and agroforestry (p<0.01), while male plot managers were more likely to adopt crop rotation (p<0.01). The study showed that adoptions of CSPs are strongly influenced by gender of plot manager suggesting that efforts to promote green manure and agroforestry should target female farmers who would warmly welcome the complimentary role these practices played in plots where they are adopted.


Dear Sir, The incidence of recurrence of pressure regurgitation following a successful conventional external dacryocystorhinostomy (CEDCR) is about 5%. The risk factors for failure of lacrimal drainage surgery include traumatic aetiology, recurrent attacks of acute dacryocystitis and repeat surgeries. Conflicting views regarding the influence of age on the success rate of CEDCR are seen in the literature. The relation between age and success of DCR has usually been described in relation to paediatric DCR and rarely in adult patients. However, no individual cases mentioning an increased propensity of failure of dacryocystorhinostomy in young patients have been reported earlier. Here, we report three young patients who presented with recurrence of pressure regurgitation within a short period following a successful CEDCR.


This study examines Nigeria's political leaders' framing during the #BringBackOurGirls movement campaign using two selected national newspapers in Nigeria, i.e., the Guardian and the Vanguard newspapers. Using 46 news stories culled during the periods of April 14, 2014, to June 14, 2014, and May 29, 2015, to July 29, 2015, which represent two significant eras, i.e., when the schoolgirls were abducted, and when there was a change in government, the study argued that four frames of government failure, the desperation of citizens, politicization of government actions and heroism were dominant in both presses reportage. During the first period of study, both presses were critical of President Goodluck Jonathan and his inability to secure the release of the abducted Chibok schoolgirl as they used frames of "liar", "clueless", and "failure" amongst others to characterize his government actions and inactions. However, during the second study period, both presses were less critical of President Buhari as they ascribed the "hero" frame to him due to his vast military experience. Nevertheless, the ideological position of both newspapers influenced their reportage as Guardian news stories provided depth analysis, while Vanguard newspaper stories lacked depth.


The ability of a mesoscale model to forecast local diurnal winds is largely determined by horizontal resolution and treatment of local surface feature data. The US Army Battlescale Model (BFM) reproduces these types of local surface flow patterns. The current effectiveness of the model is restricted due to lack of high-resolution surface data (albedo, soil moisture, snow cover). A 2 km grid has been created near the Great Salt Lake, and two 7-h model simulations generated. The day is in late May, during a time of weak synoptic flow, with each run initializing at 1200 h UTC (0500 h LST). One run initializes the surface fields with uniform values, while the other uses more realistic values over the regions of the salt flats and Great Salt Lake.


ABSTRACT This was a study of 1,093 adolescents from six different public high schools, where the same integrated theoretical model of control and social learning theories fit the data on alcohol use, heavy alcohol consumption, use of marijuana, criminal behavior, sexual exploration, and suicidal thoughts. It was observed that the model explained significantly more variance in some of these forms of delinquency than in others, indicating only equivocal support for the deviance syndrome argument in the literature. This study also found that religiosity was a significant influence only on criminal behavior, whereas the feedback eifect of delinquency on religiosity was significant for all forms of delinquent behavior studied. The importance of this particular finding was discussed in relation to previous studies, since almost all prior research has used statistics that do not consider reciprocal eifects. In the present study, the reciprocal effects between religiosity and various forms of delinquency were ana...


Based on theories of simulated annealing(SA)、genetic algorithm(GA)、parthenongenetic algorithm(PGA) and simulated annealing genetic algorithm(SAGA),the major merits and shortcomings of SA、GA and PGA are analyzed.According to the merits complementary nature of SA and PGA,a new algorithm——parthenon-genetic simulated annealing algorithm is proposed.The synthesizing of the merits of the two algorithms,reconstruction operation of gene in every generation in PGA has been improved.The traditional cooling method has been improved too.Between the operations of two generations,the algorithm adds a process which sorts the chromosomes in according to fitness function.In experiments three groups city data's traveling salesman problem(TSP) problems with the five algorithms mentioned above are used.It shows that the SAPGA's average optimal solution is the least, and the convergence time is the shortest.


Results on spectroscopy from the H1 and ZEUS collaborations are presented. The main focus is to search for baryon states which could be interpreted as pentaquarks. This includes states decaying to K^0_sp and K^0_s\bar{p}, \Xi\pi and D*p. In addition an analysis of K^0_sK^0_s resonances is covered.


Acknowledgments Introduction Adrian C. Brock1 Constructing Subjectivity in Unexpected Places Johann Louw2 Transatlantic Migration of the Disciplines of the Mind: Examination of the Reception of Wundt's and Freud's Theories in Argentina Cecilia Taiana3 From Tradition through Colonialism to Globalization: Re?ections on the History of Psychology in India Anand C. Paranjpe4 History of Psychology in Turkey as a Sign of Diverse Modernization and Global Psychologization Aydan Gulerce5 Origins of Scienti?c Psychology in China,1899-1949 Geoffrey Blowers6 Behavior Analysis in an International Context Ruben Ardila7 Internationalizing the History of U.S. Developmental Psychology John D. Hogan and Thomas P. Vaccaro8 Psychology and Liberal Democracy: A Spurious Connection? Adrian C. Brock9 Double Rei?cation: The Process of Universalizing Psychology in the Three Worlds Fathali M. Moghaddam and Naomi Lee10 Psychology in the Eurocentric Order of the Social Sciences: Colonial Constitution, Cultural Imperialist Expansion, Postcolonial Critique Irmingard Staeuble11 Universalism and Indigenization in the History of Modern Psychology Kurt DanzigerPostscriptAdrian C. BrockContributors Index


The one-dimensional model for the unidirectional shearing of a slab is investigated for the situation in which localized plastic deformation is induced by an inhomogeneity in the thermal flux. The problem is treated as a perturbation of the elastic solution, which persists until plastic deformation becomes significant. The analysis utilizes singular perturbation techniques, with the thin zone of shear localization identified as a boundary layer. It is found that the evolution of the temperature and stress perturbations are governed by only one parameter, which involves the various material constants. Numerical results indicate that the magnitude of this parameter plays an essential role in the growth of the perturbations and hence in the formation of a shear band.


Aiming at the problem of trust barriers for power users to traditional metering and payment services, an on-chain and off-chain collaborative model of power information collection integrating "standardization theory and blockchain technology" was proposed. In this paper, the standardization theory of "unification, combination and modularization" and blockchain technology are applied in the new power system electricity information collection scenarios, which can realize the security protection of power metering data source and transmission process, thus increasing the credibility of metering and payment data. Firstly, an on-chain and off-chain collaboration model is designed, including an off-chain procurement system model based on composition, an intermediate interactive interface model based on unification, and an on-chain blockchain system model based on modularization. Secondly, the typical application analysis of off-chain link, intermediate interactive interface link and on-chain link is carried out for the problem of on-chain trusted data. Aiming at the problem of off-chain data security, the terminal integration technology and distributed fusion authentication technology are proposed. Aiming at the problem of intermediate data transmission interface, two methods, API technology and intelligent contract technology, are proposed. A distributed transaction method is proposed to solve the blockchain transaction problem. Finally, the paper summarizes and prospects the whole paper.


A storage container for a vehicular seat includes a cushion pan for supporting a cushion. A lateral support bar extends between opposing side members and is positioned below the cushion pan. A container housing is disposed between the opposing side members and is fixedly attached to an underside of the cushion pan. A rear clamp of the container housing defines a containment region within which the lateral support bar is disposed. The rear clamp defines a surface engagement with the lateral support bar and is slidably engaged with the lateral support bar. Generally vertical displacement of the container housing relative to the lateral support bar biases the lateral support bar against the rear clamp to define an absorbing state of the rear clamp that receives at least a portion of the generally vertical displacement of the container housing relative to the lateral support bar.


We state and prove the square root scaling laws for the amount of traffic injected by a covert attacker into a network from a set of homes under the assumption that traffic descriptors follow a multivariate Gaussian distribution. We numerically evaluate the obtained result under realistic settings wherein traffic is collected from real users, leveraging detectors that exploit multiple features. Under such circumstances, we observe that phase transitions predicted by the model still hold.


Faculty leaders (union head or faculty association head) from the 305 member colleges in the 19‐state North Central Region were surveyed to determine the status and effectiveness of post‐tenure evaluation within each institution. Responses indicate that there is overwhelming support for the need to review tenured faculty for purposes of development and improvement. However, the effectiveness of current systems in accomplishing this goal is suspect. The major reasons cited for ineffectiveness include the inability of the evaluation to tie directly to faculty development and the lack of credible mechanisms to reward meritorious teaching and deal effectively with substandard teaching. Suggestions for improvement include development of an evaluation plan which, over time, can join formative and summative results.


A general practice study has shown that strong opioids are most commonly prescribed for back or joint pain, and highlights the urgent need for Irish guidelines on opioid use in primary care.


# How doctors learn may explain results {#article-title-2}

EDITOR—Wennberg et al hypothesise that marked variation in use of healthcare resources at the end of life may be explained largely by variations in the supply of doctors and beds.1 Although this may play an important part, …


A well-known criticism of portfolio choice models with CARA utility is the absence of wealth effect the dollar amount invested into risky assets does not depend on wealth. We propose a simple and tractable way of incorporating the wealth effect by making the absolute risk aversion parameter wealth-dependent. We then apply our idea to two economic settings that look at the impact of information acquisition on portfolio choice. First, in a setting with Bayesian investors, we demonstrate that our method leads to a simple, tractable analysis as opposed to the alternative approach of using CRRA utility and resorting to approximate solution. Second, we present a model with ambiguity-averse investors and show that the model explains several observed patterns of households' stockholding: a) nonparticipation of a large fraction of households, with poorer ones more likely to stay away from the stock market, b) wealth share invested into risky assets increases with wealth, c) market participation increases over time, while the equity premium decreases.


The purpose of this research was to study effects of microwave treatment on China aster seed germination,vigour and infestation with fungi, at temperature 20?C. The seeds were treated in microwave oven (power 850 Wheating power) in dry conditions and in water for 10, 20, 30, 40, 50, 60, 90, 120 and 180 s respectively.


The benefits of urban green space for city residents has long been recognised. Indeed, in the UK, the impetus for the development of urban parks in the mid-1800s was specifically to benefit the public's health. More recently, the potential impacts on physical and mental health (both directly and indirectly) have become major drivers of the developing blue-green infrastructure strategies for many modern cities. However, there have been a number of questions raised about how easy it is to access green space for all communities and individuals. Factors associated with accessibility include the location and physical configuration of urban green space, including both real and perceived risks such as personal safety. In addition, it is becoming clear that access to natural environments has a cultural dimension and urban green space such as parks are no exception to this. The presentation will examine the current state of knowledge in the UK, where the park movement began and has more recently been revitalised. The cultural implications of green space development will be explored in the context of large modern cities. Implications for the design and development of blue-green infrastructure in Qatar will be discussed in the light of current UK developments.


The current approach to countering the threat of improvised explosive devices (IEDs) in Afghanistan has met with limited success. The relative lack of success may be in part because the current approach is not holistic and discounts the social systems that foster the IEDs. Insurgents are using IEDs as a tool to further their strategic aims, but the coalition and to a lesser extent the Government of the Islamic Republic of Afghanistan (GIRoA) are attacking the IEDs as if they are an end in and of themselves. Combining network disruption with information change maximizes the opportunities for mitigating the IED threat. More specifically, to mitigate the IED threat requires disrupting the social and economic systems associated with IEDs, and at the same time providing alternative economic opportunities and improving rule of law and governance at the local level. In other words, counter-IED (C-IED) must be Counter-Insurgency (COIN) centric to be successful. This paper reviews the current state of C-IED efforts, identifies five main problems with the current approach, and suggests changes to reduce or mitigate the IED threat in Afghanistan.


Measurements of the millimeter-wave backscatter from deciduous (leafed) trees are explained using a simple scattering model. The backscatter from individual leaves was measured in the laboratory and used to justify the use of an average leaf radar cross section when computing the normalized radar cross section (NRCS) of tree canopies. NRCS measurements of canopies show that the direction in which incident radiation impinges on the canopy is an important factor in characterizing radar backscatter. Comparisons of measured NRCS values demonstrate that planophil and erectophil trees can be distinguished based on their backscatter at 215 GHz. >


The XIII Forum of the International Federation of Psychoanalytic Societies (IFPS), on the theme ''The Multiple Faces of Perversion'' and hosted by the Cı́rculo Psicoanalı́tico de Minais Gerais (CPMG), took place in Belo Horizonte, Minais Gerais, Brazil, at the end of August 2004. Javert Rodrigues, the chairman of the local organizing committee, had for years told us how lovely the town was, how friendly and hospitable Brazilian people were and how successful psychoanalysis was in Brazil, so we were happy finally to have the chance to experience this. About six hours by car from Rio de Janeiro, Belo Horizonte, founded in 1897, has over 2.5 million inhabitants and is the third largest (and richest) Brazilian town after São Paulo and Rio de Janeiro. Arriving on the Friday August 20, I was able, together with the other members of the Editorial Board, to visit the old mining capital, Ouro Preto, and enjoy the colourful and wild Brazilian landscape. The Editorial Board worked through the Saturday, hosted by the local society, represented by Eliana Rodrigues Pereira Mendes and Paulo Ceccarelli. The CPMG, founded in 1963, has a very wellorganized training institute, with a rich collection of books and tapes. Our Brazilian colleagues were even able to produce a videotape / to celebrate their fortieth anniversary / on the history and scientific profile (basically Freudian and Lacanian) of their society. On the Sunday, the Executive Committee of the IFPS were, among other things, able to develop a good exchange with the Editors-in-Chief on the future of the International Forum of Psychoanalysis / and on collaboration with the publisher, Taylor & Francis. The Assembly of Delegates, which met on Monday, congratulated the Editorial Board for the journal having been accepted for inclusion in the next PEP disk (the CD-Rom featuring the major psychoanalytic journals and all articles published by them, due to appear in 2005), and also approved three new societies joining the Federation: Schweizerische Gesellschaft für Daseinsanalyse (Zurich), the National Psychological Association for Psychoanalysis (New York) and the Mexican Séminario de Sociopsicoánalisis (Mexico City). In addition to the Argentinian Instituto de Psicoanálisis Contemporáneo, we now also have a second Study Group: the Kaunas Study Group of Psychoanalysis, Lithuania. IFPS now has twenty-seven Member Societies in sixteen countries and two Study Groups comprising approximately 2350 members. On the website's home page, www.ifp-s.org, readers can find all the information pertaining to our Federation. A new roster of IFPS members was also produced and sent to the Member Societies for distribution in order to improve and facilitate communication and scientific exchange. For the first time in the IFPS's history, two societies competed to organize a forthcoming Forum: it was decided to hold this in Santiago de Chile in 2008 / despite close competition from Rebeca Aramoni's proposal to meet in Monterrey, Mexico. The next Forum, will be held in Rome, Italy, on May 25 /28 2006. Maria Luisa Tricoli distributed a brochure to the Assembly featuring the main organizational details and entitled ''Psychoanalysis in transition: the interplay of internal and external world ''. Further information can be found at www.sipreonline.it, website of the Società Italiana di Psicoanalisi della Relazione, an IFPS member society since 1994. At the end of the Assembly of Delegates meeting, Sonia Gojman, Mexico City, and Carola Mann, New York, were re-elected as Secretary General and Deputy Secretary General of the IFPS for another four years. We were also glad to hear of the Federation's good financial status. A moving ceremony was held at the Thursday Gala Dinner, at which Jan Stensson, resigning as Editorin-Chief after thirteen years, was celebrated and thanked by all for his invaluable contribution to the foundation and development of International Forum of Psychoanalysis . Before the official opening of the Forum on August 24, a pre-Forum was held, meant as an ''Introduction to Lacanian Theory''. This was very clearly presented to the mostly foreign participants from Europe and North America, not really familiar with Lacan's language and theory, by Antonio Quinet, Rio de Janeiro, in the morning and by Sandra Kruel, Belo Horizonte, in the afternoon session. Quinet started out from Lacan's (1901 /1981) famous ''return to Freud'', in terms International Forum of Psychoanalysis. 2005; 14: 54 /62


Introduction: Severe renal impairment (RI) is a common complication of multiple myeloma (MM). Effective anti-MM therapy and supportive care can restore renal function in several patients, but we lack biomarkers that could predict renal outcomes. Neutrophil gelatinase-associated lipocalin (NGAL) is one of the earliest and most robust markers of acute kidney injury while serum Cystatin C (CysC) reflects renal function more accurately than creatinine and correlates with both tumor burden and renal function in MM. GDF-15 is secreted by bone marrow stromal cells and high serum levels indicate a poor treatment prognosis and a high risk of progression to dialysis in AL amyloidosis. Our aim was to evaluate serum NGAL, CysC, and GDF-15 in MM patients with severe RI defined as eGFR<30 ml/min/1.73m2, by CKD-EPI formula, including those on dialysis, as biomarkers for prediction of renal responses.
 Patients & Methods: MM patients who presented with myeloma-related severe RI in the Department of Clinical Therapeutics (Athens, Greece) were included in this study. NGAL, CysC and GDF-15 were measured in the same frozen serum sample collected before the administration of any therapy. Serum NGAL was measured using ELISA (BioPorto Diagnostics A/S, Gentofte, Denmark), while CysC was measured using a latex particle-enhanced nephelometric immunoassay (Dade Behring-Siemens Healthcare Diagnostics, Liederbach, Germany). GDF-15 was measured by a novel immunoassay, the Elecsys GDF-15 assay (Roche Diagnostics International Ltd, Rotkreuz, Switzerland), which is based on the sandwich immunoassay principle using biotin-streptavidin technology. Patients on dialysis received dialysis with regular membranes. IMWG renal response criteria were used.
 Results: In total, 101 newly diagnosed MM patients with severe RI were included in this analysis. Median creatinine was 4.6 mg/dl (range 2->10 mg/dl), median eGFR (ml/min/1.73 m2) was 11.3 (1.3-29.8) and dialysis was required in 35 (35%) patients. The median age was 71 years; median involved FLC was 4740 mg/L; hypercalcemia was found in 24%, LDH ≥ULN in 44% and high-risk cytogenetics in 25% of patients, while 98% of patients were classified as having ISS-3 and 49% as having R-ISS-3 disease stage. Treatment was bortezomib-based in all patients (in 21% VD and in 79% a triplet: VCD or VTD). Median NGAL levels were 182.3 ng/mL (range 20-550 ng/ml) and of CysC were 3.3 mg/L (0.9-8 mg/L); there was a strong correlation between NGAL and CysC levels (R2=0.653, p<0.001). There was also a strong correlation of both CysC and NGAL with eGFR (for CysC: R2=0.615, p<0.001 and for NGAL: R2=0.464, p<0.001). Both NGAL and CysC levels were higher in patients requiring dialysis vs those not in dialysis (median NGAL: 308 vs 166 ng/mL, p<0.002 and median CysC: 4.99 vs 2.83 mg/L, p=0.008). No significant correlations were observed with GDF-15 and the parameters tested. Renal response (Rrenal) was achieved in 63% of patients, including 45% with major Rrenal. Importantly, 40% of patients who required dialysis became dialysis independent. Median time to Rrenal was one month and median time to dialysis independence was two months. Lower levels of NGAL (p=0.0003) and CysC (p=0.03) were associated with higher probability of major Rrenal among patients with severe RI. Baseline eGFR, levels of sFLC and GDF-15 did not correlate with major Rrenal. None of these markers was associated with probability of dialysis independence among patients who required dialysis. Based on ROC analysis, in patients with severe RI (but not on dialysis), NGAL <138 ng/ml was strongly associated with major Rrenal (80% vs 20% at 3 months, p<0.001; Figure). Regarding CysC, levels <2.9 mg/L were associated with higher probability and shorter time to major Rrenal (p=0.012). In multivariate analysis performed in patients not on dialysis, that included age, NGAL, CysC and eGFR, only NGAL <138ng/ml remained a significant prognostic factor associated with major Rrenal (HR 5, 95% CI 2-18, p=0.002).
 Conclusions: Serum levels of NGAL were independent predictors of major renal response in MM patients with severe RI. Thus, serum NGAL could identify MM patients with severe RI who should be treated with more aggressive therapies and more effective and rapidly acting antimyeloma regimens. The absence of any predictive value of GDF-15 in MM-related severe RI in contrast to AL amyloidosis patients reflect the different biology of RI in these plasma cell dyscrasias.
 Figure

 Dimopoulos: Sanofi Oncology: Research Funding. Kastritis:Amgen: Honoraria, Research Funding; Janssen: Honoraria, Research Funding; Genesis: Honoraria; Prothena: Honoraria; Pfizer: Honoraria; Takeda: Honoraria. Papassotiriou:Roche: Employment. Gavriatopoulou:Amgen: Honoraria; Janssen: Honoraria, Other: Travel expenses; Genesis: Honoraria, Other: Travel expenses; Takeda: Honoraria, Other: Travel expenses. Terpos:Janssen: Honoraria, Other: Travel expenses, Research Funding; Amgen: Honoraria, Research Funding; Celgene: Honoraria; Takeda: Honoraria, Other: Travel expenses, Research Funding; Genesis: Honoraria, Other: Travel expenses, Research Funding; Medison: Honoraria.


Neonaticide (defined as the killing of an infant within the first 24 hours of birth) has occurred throughout history for a variety of reasons. Law enforcement files involving 40 female offenders resulting in 41 infant deaths were examined. Descriptive and frequency statistics revealed that the majority of offenders were young women who had never been married and had no criminal or psychological history. However, approximately a quarter of the sample did not fit these characteristics, which has implications for broadening the scope of investigations. The findings of this research identified four main challenges associated with neonaticide investigations: (a) variation in offender characteristics and situational factors, (b) intermittent denial of the pregnancy, (c) the physical resiliency of the offenders, and (d) lack of documented mental health and criminal history. Correspondence should be addressed to Kristen R. Beyer, P.O. Box 6566, Fredericksburg, VA 22403; email: email@example.com and/or Joy Lynn E. Shelton, FBI Academy - NCAVC, Quantico, VA 22135; email: firstname.lastname@example.com


Retigabine (Trobalt) is a new antiepileptic drug with a novel mode of action and licensed as adjunctive treatment for partial‐onset seizures. In our New products review Steve Chaplin presents the clinical data relating to its efficacy and adverse events and Dr Aidan Neligan discusses its place in the treatment of epilepsy. Copyright © 2011 Wiley Interface Ltd


A review is given of the present state of experimental and theoretical knowledge of the proton-proton and antiproton-proton forward scattering, with special attention to applications of phenomenological dispersion theory in elucidating this interaction. The topics covered include the treatment of unphysical region, low-energy parameterizations, dispersion relation calculations of the real parts and the meson-nucleon coupling constants, analyses of the data by recently developed numerical analytic continuation techniques, high-energy phenomenology, and evaluation of sum rules.


The local loop includes mainly copper twisted pairs, which connect each home and office and provide 64 kbps data rate. As the demand of individuals grows, more communication volume is required to be transmitted over the local loop. New applications (video conference, data transmission, video on demand, multimedia applications, teleshopping, edutament), which demand high data-rates are becoming a reality. The HDSL and the ADSL technologies are able to solve this problem and enable the provisioning of new applications and services over the existing copper infrastructure. This will offer a rapid deployment of these services to many people around the world, now connected to the telecommunication network by means of simple twisted pairs. The paper summarizes the main characteristics of the network architecture of multi media services, HDSL (high bit rate digital subscriber line)/ADSL (asymmetric digital subscriber line) technology in services and interactive video service architecture.


In this paper,the oxidative desulfurization(ODS)system is directly applied to deal with the catalytic oxidation of sulfur compounds of sulfur-containing model oil by dielectric barrier discharge(DBD)plasma in the presence of air plus an extraction step with the oxidation-treated fuel put over ionic liquid[BMIM]FeCl4(1-butyl-3-methylimidazolium tetrachloroferrate).This new system exhibited an excellent desulfurization effect.The sulfur content of DBT in diesel oil decreased from 200 ppm to 4.92 ppm(S removal rate up to 97.5%)under the following optimal reaction conditions:air flow rate(v)of 60 mL/min,amplitude of applied voltage(U)on DBD of 16 kV,input frequency(f)of 79 kHz,catalyst amount(ω)of 1.25 wt%,reaction time(t)of10 min.Moreover,a high desulfurization rate was obtained during oxidation of benzothiophene(BT)or 4,6-DMDBT(4,6-dimethyl-dibenzothiophene)under the aforementioned conditions.The oxidation reactivity of different S compounds was decreased in the order of DBT,4,6-DMDBT and BT.The remarkable advantage of the novel ODS system is that the desulfurization condition applies in the presence of air at ambient conditions without peroxides,aqueous solvent or biphasic oil-aqueous solution system.


The Substance of nominal scaling , ordinal scaling , interval scaling and radio scaling is the result that the spatial construction of the research object X was apprased by the apprased partial odering set(A,≤).Becauses of XA therefore the A_(j)∈A presents the function of x_(i)∈X.According to the study,the mathematical definition and geographic variable for nominal scaling,ordinal scaling,interval scaling and radio scaling are obtained respectively.The correctness is proved by the examples.


This study presents the direct and indirect benefits of certification, in a coffee estate in southern Minas Gerais. It uses as a case study methodology, in exploratory research. The farm chosen for analysis is certified UTZ Certified, BSCA (Brazil Specialty Coffee Association). The study brings as reasons the concepts of sustainability, traceability, certification. Through the interviews, can conclude that certification has brought to the farm analyzed direct and indirect benefits. Like direct benefits, can be highlighted the conquest of new markets and adding value to the product. It is understood, however, that the greatest benefit of certification is to improve the management of the property, with reduced waste, lower cost of production and improving the efficiency of processes. In addition, the certification ensures traceability of the production process, which brings a guarantee for both the producer and consumer. The organization encouraged by certification also contributes to increasing the quality of the final product.


In what has become known as an Allen charge, a trial judge gets tough with jurors who believe they cannot agree. Jurors in the minority are told to reconsider whether their views are sound, given the greater number of jurors arrayed against them. Delivered with the right emphasis and tone, such an instruction can break a jury deadlock. The Allen charge gains its name from Allen v. United States, an 1896 Supreme Court opinion that upheld such a charge. Nearly a century later, the Court praised the Allen opinion's reasoning as "beyond dispute." Today, the Allen charge remains a staple of modern federal trial practice. Yet there was more to Allen's case than the Allen charge. Alexander Allen was a poor black teenager convicted of murder. He was one of many whom the federal court in Fort Smith, Arkansas, sentenced to hang. After a harrowing series of trials and appeals, Allen ended up in the Supreme Court, sentenced to die, with no lawyer to represent him. By the 1890s, the Court had spent over a century deciding cases brought to it by lawyers. It now faced a new kind of appeal, brought by condemned prisoners who, like Allen, were too poor to hire a lawyer. This paper explores how Allen's case unfolded, and how the Supreme Court handled his appeals.


Abstract The scallop Argopecten ventricosus (Sowerby II 1842) supported an important fishery in the Gulf of Panama (Pacific Panama) during 1981–1990, but the fishery essentially collapsed in 1991. To determine if the A. ventricosus population in one major fishing ground, Las Perlas Archipelago, has recovered almost 15 years after that collapse, we interviewed fishermen, reviewed historical data about scallop export markets and fishing grounds, and assessed the state of the scallop population using traditional local trawling methods. During four expeditions (2000–2004), we intensively surveyed 183 trawling stations, which included the major shallow fishery sites as well as other deeper areas within the archipelago. We collected hundreds of relic adult and juvenile scallop shells, but we retrieved only 30 live individuals. This suggests that minimal recruitment has occurred in the archipelago and that the fishery remains collapsed. We argue that this population's failure to recover may be because of a lack of suitable available habitats for juveniles, predation and variation in local oceanographic conditions, as previously suggested. Further studies are needed to fully determine why the scallop population has failed to recover. Application of mariculture techniques may be required to restore the stock and repopulate A. ventricosus natural banks in Las Perlas Archipelago.


Politics are a fundamental part of human society, and as such, studies have been done to attempt to find ways to predict one's political views, particularly for advertising purposes. In recent years, politicians and political movements have begun to employ the use of popular music or musicians to accompany their causes and advertisements. Studies have been done in the past to determine whether or not a correlation exists between politics and music, yet most have fallen short in data collection or simply did not achieve any results with correlation. This study attempts to go beyond previous studies by using more accurate data reporting with Spotify's API, which allows for data collection from a participant's entire listening history on the platform. All of the programming, survey questions, excel formulas and instructions can be found at https://github.com/ajlacognata/researchspotifyapp if you wish to attempt to replicate this study.


This article studies the history of psychanalysis in order to bring to light the theoretical assumptions and the epistemological foundations used to promote artistic mediations in psychic care. Based on this historical investigation, the idea is to specify the framework and the processes at work in clinical practice with therapeutic mediations. The historical itinerary will be articulated most particularly around the interaction between psychoanalysis and artistic creation in Freud's work, around the Winnicottian theory of transitionality and the history of artistic mediations in the psychoanalytical psychotherapy of children and in psychosis.


When I was working on my MSW, I read a statistic that would not let go of me, "Nearly 40% of patients on dialysis had diabetes." I began to wonder what dialysis was like and how a person who struggled to manage one chronic illness would now cope with a second chronic condition. I sought an experience that would complement my interest in helping people with chronic illness to manage their disease and engage in their care. My prior experience had been with diabetes education and support. Now it was time to go to the next step. I asked our field coordinator if she had any contacts with dialysis clinics and whether I could do my second year MSW field placement there. She had never had a student do an internship at a dialysis clinic, but was open to the idea.I contacted the largest provider in our area and enquired about an internship. The details were worked out over the summer before my second year and I began my internship in the fall. I can say that the experience made me proud to be a social worker and inspired me to continue my education. There are some elements of the internship that I believe could be replicated for other students. Interdisciplinary Experience The dialysis clinic provided an interdisciplinary experience. I began my training over the summer when I took the Kidney School online training provided by the National Kidney Foundation (NKF). I learned about the physiology of kidney disease, dietary needs and restrictions, and the emotional aspects of care. I was encouraged to work with nurses, dieticians, physicians, and office personnel to know what role each discipline played in caring for patients. I got to know patients in deeper ways than if I had just devoted myself exclusively to a social work orientation. It was apparent that caring for a dialysis patient was a complex endeavor and required an army of people. Multiple Social Workers Allow Interns to Find Their Own Way I worked closely with five different social workers during my yearlong internship. This was invaluable, as a dialysis social worker has a long list of responsibilities and a variety of ways for accomplishing those responsibilities. Seeing different ways of performing the same job allowed me to find "my way" of being a nephrology social worker. The social workers were open to my doing a variety of duties and gave me freedom to organize and accomplish tasks in my own personal style. Mistakes are Just Learning Experiences in Disguise I was affirmed even in my failures. My first day at a new clinic, I spent half an hour updating a yearly review with a patient. My social worker had come by to see how things were going and she smiled when she left. It wasn't until I was ready to begin the educational part of my visit that I realized I was meeting with the wrong patient! I had called the patient by the wrong name for the entire visit and he never corrected me! I excused myself and hurried to apologize to my social worker; she just smiled and said, "Well, what did you learn about Mr. Smith?" Then we discussed the importance of confirming the identity of a patient. I never made that mistake again! Variety is the Spice of an Internship My tasks varied with each new clinical experience. I was involved in planning and facilitating monthly support group meetings, providing information about Advance Directives and Living Wills, conducting intakes with new patients, and updating insurance and contact information.One of my favorite tasks was administering Kidney Disease Quality of Life (KDQOL) surveys to patients. After administering the surveys, I scored them, recorded the scores, compared past scores, and prepared patient information sheets. I would follow up with patients by reviewing the results and creating an individualized intervention to improve areas of poor functioning. I learned a great deal about patients through these conversations; many were very happy to have someone who would actively listen and help them to improve their functioning. …


1. The vessel of Gnetum with the single large perforation in its end wall has been evolved by the enlargement and fusion of several haphazardly arranged bordered pits. 2. The vessel of angiosperms with the similar single large perforation has been evolved from the type with many long, narrow, scalariform perforations. 3. On account of the entirely different courses of evolution by which they were produced, there can be no genetic connection between the vessels of the two groups. They furnish a remarkable illustration of independent development of similar structures. 4. The possession of vessels by both angiosperms and Gnetales cannot be used as an argument in favor of the derivation of angiosperms from Gnetales or of both from common ancestors.


Dick Maurice Alan Sutton, pounds sterling12.99, pp 99 ISBN 0 07509 0831 9

If today's general practitioners feel hard done by they might reflect on the workload of their predecessors. For Drs Pinckney and Maurice, who became partners in 1792, there were no rotas and they both worked a seven day week making several visits each day over a radius of ten miles or more from their practice in Marlborough. Considering the poor quality of roads, the harshness of winters, and the need to change …


The design of polyelectrolyte multilayers (PEMs) that can be prefabricated on an elastomeric stamp and mechanically transferred onto biomedically‐relevant soft materials, including medical‐grade silicone elastomers (E'∼450–1500 kPa; E'‐elastic modulus) and the dermis of cadaver skin (E'∼200–600 kPa), is reported. Whereas initial attempts to stamp PEMs formed from poly(allylamine hydrochloride) and poly(acrylic acid) resulted in minimal transfer onto soft materials, we report that integration of micrometer‐sized beads into the PEMs (thicknesses of 6–160 nm) led to their quantitative transfer within 30 seconds of contact at a pressure of ∼196 kPa. To demonstrate the utility of this approach, PEMs were impregnated with a range of loadings of silver‐nanoparticles and stamped onto the dermis of human cadaver skin (a wound‐simulant) that was subsequently incubated with bacterial cultures. Skin dermis stamped with PEMs that released 0.25 ± 0.01 μg cm−2 of silver ions caused a 6 log10 reduction in colony forming units of Staphylococcus epidermidis and Pseudomonas aeruginosa within 12 h. Significantly, this level of silver release is below that which is cytotoxic to NIH 3T3 mouse fibroblast cells. Overall, this study describes a general and facile approach for the functionalization of biomaterial surfaces without subjecting them to potentially deleterious processing conditions.


The aim of this study was to assess the current extent of participation by Russian small enterprises in regional public procurement. We discussed how legislation affects the volume of contracts awarded to small enterprises. We calculated the number of contracts per 100 small enterprises, how much the number and value of such contracts account for in the total number and value of contracts concluded with all suppliers per region, as well as what is the average value of contracts per small enterprise and the average value of one such contract. In order to ensure benchmarking for enterprises located in different regions, such enterprises were assessed on the basis of relative indicators. This study used official statistics accumulated with regard to all public procurement in the regions. The data on the number of contracts and their value for the period from 2010 to 2014 were used. For the purposes of empirical data analysis, the normal distribution probability density functions set for all the indicators in question were used. The findings of this study and the tools used for assessing the extent of participation by small enterprises in public procurement can be used when researching entrepreneurship, as well as to justify the contract system development programs in Russia. Such information is important for entrepreneurs, as it enables them to assess the feasibility and consequences of participation in public procurement.


Generally,the theory of translation has been applied to conduct research on the plural representing mehenism,caused by vague language in therespects of linguistics,philosophy and rhetorics. Nevertheless,not enough attentionhas been paid to to the poly explanations of non-vagueness in theprocess of translation. Actully,thereare also multi-explamnation issues in the non vague vocabulay. Hense such kind of poly explanations can be found in the adaptability,cultural protypes,objective cognition and subjective aesthetic experience. As a result,enough attention should be paid to the multi-explanations to the vagueness of words in the literature text.


We studied frequency and temperature dependences of impedance, electric modulus, and dielectric permittivity of Bi 2/3 Cu 3 Ti 4 O 12 in the ranges of 10 −1 –10 6 Hz and −150–200 °C, respectively. We first observed two electrical responses in the impedance and modulus formalisms. Then we detected a Debye-like relaxation in the permittivity formalism. Most interestingly, we found that the large dielectric constant of Bi 2/3 Cu 3 Ti 4 O 12 is independent of the temperature and frequency below 150°C. The results are interpreted in terms of a two-layer model with conducting grains partitioned from each other by poorly conducting grain boundaries. Using this model, we attributed the two electrical responses in impedance and modulus formalisms to the grain and grain-boundary effects, respectively, while the detected Debye-like relaxation and large dielectric constant were well explained in terms of Maxwell-Wagner relaxation.


The development of distributed multimedia applications has always been a challenge for both expert and nonexpert developers. Middleware and supporting frameworks have emerged to simplify this process by providing reusable components that can be plugged together in many configurations to help application developers building up their applications. In distributed multimedia, the adoption of such frameworks allows the exchange of media (i.e. audio, video, etc.) and configuration data (i.e. where, how, etc.) transparently through the network. Application developers do not have to deal with details related to the location of data sources and destinations, network protocols used, or even the quality of service (QoS) requirements at the network level. Most framework designers tend to concentrate on the aspect of generalising and enhancing the functionality of the framework components and leave the communication between these components to be managed by one of the standard distributed object platforms such as CORBA, DCOM or JavaRMI. This paper describes research undertaken to tackle the problems of designing and managing communication between distributed multimedia components. The design of a supporting framework is explained with emphasis on the communicational aspect of its components. The paper also includes a case study which illustrate the use of the framework.


University adult educators who ascribe real significance and growth for the concept of &dquo;lifelong learning&dquo; to the rising interest in continuing education for professionals should pause to consider some remarks in the latest work of the esteemed political economist Galbraith. Galbraith points out that: &dquo;It is the vanity of educators that they shape the educational system to their preferred image. They may not be without influence but the decisive force is the economic system. What the educator believes is usually latitude to respond to economic need.&dquo; Galbraith notes that we educators have masked this servitude with a


The paper presents a general methodology of adaptive control based on fuzzy model to deal with unknown nonlinear plants. The problem of parameter estimation is solved using a direct approach, i.e. the controller parameters are adapted without explicitly estimating plant parameters. Thus, very simple adaptive and control laws are obtained using Lyapunov stability criterion. The generality of the approach is substantiated by Stone-Weierstrass theorem, which indicates that any continuous function can be approximated by fuzzy basis function expansion. In the sense of adaptive control, this implies the adaptive law with fuzzified adaptive control parameters. The global stability of the control system is assured and the tracking error converges to the residual set that depends on fuzzification properties. The simulation results showed that the proposed approach has high adaptation ability and consequently good performance for nonlinear system


Objective To investigate the effect of antisense oligonucleotide (ASODN) targeting survivin on the apoptosis and proliferation of renal cancer cell line 786-O. Methods ASODN targeting survivin was designed and constructed.Cultured cells were divided into 6 groups:control group,liposome group, sense oligonucleotide (SODN) group,200 nmol/L ASODN group,400 nmol/L ASODN group and 600 nmol/L ASODN group.Cells were transfected for 24 h and then harvested to carry on the next tests.Morphological changes of cells were observed by transmission electron microscope. Survivin protein expression was detected by immunohistochemical method and imaging analysis. Apoptosis index (AI) and cell cycle were examined by flow cytometry. Inhibition ratio (IR) was determined by the colorimetri MTT cell viability and proliferation assay. Results Abnormal morphological changes of cells were observed in ASODN transfected groups.Expression of survivin in ASODN groups was significantly decreased compared with control group,liposome group and SODN group.The AI of ASODN groups was significantly higher than that of other groups.The IR of ASODN groups was significantly higher than that of other groups. Conclusion Expression of survivin may decrease 786-O cells after ASODN transfection.ASODN targeting survivin can induce 786-O cell apoptosis and inhibit 786-O cell proliferation.


Differences between employees' blood pressure before and after exposure to heat in The Bottling Process area at PT Sinar Sosro Deli Serdang 2013. Blood pressure can be affected by several factors, especially in the work site that is most affected by the heat factor. Measurement of blood pressure in the work site has benefit to prevent the workers in getting some health problems, such as dehydration, hypertension and other disorders. This research is a kind of pre-experimental research with One Group Pretest Posttest approach. It aims to reveal the differences of employees' blood pressure before and after exposure to heat in The Bottling Process area at PT Sinar Sosro Deli Serdang in 2013. The sample in this research were 20 men who are all employees (total sampling) of the bottling process area which work from 08:00 a.m. to 4:00 p.m. at PT Sinar Sosro Deli Serdang. Data were collected by measuring the employees' blood pressure and will be analyzed by using paired t-test statistics. The results showed that there was no significant differences between the employees' systolic blood pressure after exposure to heat in The Bottling Process at PT Sinar Sosro with sig value 0.246 (p> 0,05). It also found in diastolic blood pressure. There was no significant differences between employees' diastolic blood pressure after exposure to heat in The Bottling Process at PT Sinar Sosro with sig value 0.606 (p> 0,05). PT Sinar Sosro is expected to enhance their efforts in controlling the workplace's heat. The prevention can be done by adding ventilations and local exhauster, provosioning rest area, water consumption system or administrative treat (job rotation). Keywords: Heat, Blood Pressure, Systolic, Diastolic


Among the congenital coronary heart diseases, atrial septal defect constitutes the 1/3 most common type. In many cases, the affected person stays asymptomatic for the duration of the youth even having big shunts. Methodologies that may be hired for figuring out the defects are : echocardiogram , chest X-ray, electrocardiogram, cardiac catheterization, MRI, CT scan, phonocardiogram . Deep learning may be correctly utilised for the automatic estimation of the illness from the test result. The purpose of this review paper is to offer an perception into ASD, the strategies for figuring out it and the application of deep learning models for distinguishing the illness. The paper opinions diverse algorithms used for identity of defects also points out the restrictions of every algorithm.


Summary By intrapatient comparison at constant phenytoin (PHT) dose, the effect of carbamazepine (CBZ) comedication on PHT was studied in a group of 24 epileptic outpatients. In half of the patients with steady-state PHT plasma concentration, a significant increase of this concentration was noted after CBZ was added to their regimen. Twenty percent showed clinical manifestations of acute drug toxicity initially thought to be CBZ related. The mean PHT plasma concentration for the 12 patients (22.7 ± 5.64 μg/ml) as well as concentration/ dose ratio for PHT (4.61 ± 1.65 μg/ml plasma per mg/kg/day dose) was significantly higher (p < 0.001) with concomitant administration of CBZ than when PHT was given alone: PHT concentration, 12.54 ± 3.93 (μg/ml and PHT concentration/dose ratio, 2.52 ± 0.78 μg/ml plasma per mg/kg/day dose. Those patients with higher PHT plasma concentrations seem to be at higher risk of PHT toxicity due to CBZ comedication.


Introduced the establshment of mathematical model of the finite difference in the calculation of the deflexion of the ancon in brief;analyzed how to establish the mathematical model of the inertia trisquares of all cross sections of the steel column of the contact line simply,and calculated the deflexion of the steel column in program,the result was consistent with the actual measurement.While designing the steel column,the method can help to fast decide if the deflexion is appropriate and adjust it in time.In production,analyze how the modify of the thickness of its main, subsidiary angle iron influences the whole steel column′s deflexion with this arithmetic also,and here by control the weight of the materials and make its shape size measure up to the standard.


Many diseases, such as childhood diseases, dengue fever, and West Nile virus, appear to oscillate randomly as a function of seasonal environmental or social changes. Such oscillations appear to have a chaotic bursting character, although it is still uncertain how much is due to random fluctuations. Such bursting in the presence of noise is also observed in driven lasers. In this talk, I will show how noise can excite random outbreaks in simple models of seasonally driven outbreaks, as well as lasers. The models for both population dynamics will be shown to share the same class of underlying topology, which plays a major role in the cause of observed stochastic bursting.


This project is a historical and topical search into handwriting evaluation. It includes a statement of the problem; a justification; definitions; a bibliography listed in historical order with annotations on 36 books and articles; and a summary and evaluation of the literature. The conclusion of the paper discusses the importance of being aware of evaluation techniques and tools that can be used to judge students' handwriting skills. The paper closes with three recommendations for teachers: (1) choose a handwriting evaluation scale, method, or tool and use it consistently; (2) have students self check their handwriting by using transparent overlays to evaluate daily progress; and (3) use an evaluation plan as a tool which lends itself to remediation. Thirty-five references are appended. (MS) xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx**xxxxxxxxxxxxxxxxxx * Reproductions supplied by EDRS are the best that can be made * from the original document. X 300000000000000(X300(XXXXXXXXXX30000(XXXRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX -4" CD LeN Literature on Evaluation of Handwriting Cr% "PERMISSION TO REPRODUCE THIS U S DEPARTMENT OF EDUCATION Office Of Educatonai Research and improvement U.1 MATERIAL HAS BEEN GRANTED BY EDUCATIONAL RESOURCES INFORMATION t\ 4 42,E V113 OA ft TO THE EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) "


Objective To explore the difference in the mirror image of nasopharyngeal structures observed using nasal endoscopy in various angles(0 °、30 °、70 ° mirror) and to analyze the advantages and disadvantages of the various lens application. Methods 70 patients with nasopharyngeal carcinoma treated by radiotherapy and with regular follow- up from June, 2012 to August, 2013 in our department were involved. Clinical data about the mirror image of the nasopharyngeal structures observed using nasal endoscopy in various degrees were retrospectively analyzed. Results the mirror image of the nasopharyngeal structures observed using nasal endoscopy in various degrees were statistically different, and the visual fields of nasal endoscopy under various angles were statistically different(P0.05), with statistical significance(P0.05). Conclusions Endoscopic imaging using nasal endoscopy with different angles in patients with nasopharyngeal carcinoma after radiotherapy can result in different mirror image, which has its respective advantages and disadvantages. The outcomes of this study can be used for reference for the selection of lens.


Objectives:  Determine incidence of complications such as difficult or failed intubation, hypoxemia, hypotension, and bradycardia in children undergoing rapid sequence intubation (RSI) in a pediatric anesthesia department in a tertiary care children's hospital.


Convolution in real time of two oppositely directed travelling magnetostatic waves of angular frequency, ω, has been observed in YIG rods, plates and epitaxial films at microwave frequencies. The multiplication process occurs through the gyromagnetic precession as in earlier frequency doubling experiments in ferrites. The necessary spatial integration and output at 2ω, is obtained either by a single turn coil or a distributed inductor, depending on the geometry of the YIG sample, with its axis being along the direction of the bias field. Detailed convolution experiments have been performed at L and S‐band frequencies on single short pulses, single long pulses and double pulses utilising magnetostatic waves in YIG plates of non‐ellipsoidal geometry. Observed bilinearity factors can be as high as 10−2(mW)−1 in contrast with values of less than 10−5(mW)−1 available from interacting travelling waves via the electroacoustic anharmonicity in lithium Niobate. Device dynamic range is predicted to be in excess of ...


Abstract This essay argues that the Middle English miracles and lyrics of the Virgin Mary borrow the language of chivalry and courtly love in their depiction of the intercessory powers of the Mother of God. Because both chivalry and courtly love bear evidence of signifying contestation during the late Middle Ages, Marian texts that use the language of both or either can themselves be seen as complex and potentially anxiogenic. Understood through the theories of Gilles Deleuze and Felix Guattari, the miracles themselves can be defined as documents of signifying alliance or as evidence of what Deleuze and Guattari call "becoming." Thus, the miracles and lyrics of the Virgin that use such fraught codes present us with an image of Mary that is unstable. An examination of such signifying alliances helps us better understand both the signifying networks at play in the later Middle Ages and the language work produced by them.


Radiative decay processes have been studied in graphene quantum dots (GQDs) by varying their size. The photoluminescence (PL) decay traces are well fitted to a biexponential function with lifetimes of τ1 and τ2, indicating their fast and slow components, respectively. The τ1 is almost constant, irrespective of the average GQD size (da) for two excitation wavelengths of 305 and 356 nm. In contrast, the τ2 decreases as da increases for da ≤ ∼17 nm, but da > ∼17 nm, it increases with increasing da for both the excitation wavelengths, similar to the size-dependent behaviors of the time-integrated PL peak energy. We propose that the τ1 and τ2 originate from size-independent fast band-to-band transition and size-dependent slow transition resulting from the edge-state variation at the periphery of GQDs, respectively.


We're entering IEEE membership renewal season. If you receive this magazine, chances are you are currently a Member of the IEEE and the IEEE Microwave Theory and Techniques Society (MTT-S). Are you planning to renew? Let me encourage you. You may wonder why I'm discussing membership in a column that covers business issues. I think MTT-S membership is important for RF and microwave engineers. And while it does not need to be, it can be viewed from a business perspective.