Objiective To investigate surgically created the distal basilic vein transposition arteriovenous fistulas for hemodialysis access.Methods The study reviewed consecutive patients in whom distal basilic vein transposition arteriovenous fistulas were created from December 2007 to December 2009.The basilic vein was anastomosed to the ulnar artery or was transposed and anastomosed to the radial artery or to the brachial artery.Results AVF creation was successful in 23 patients (86.7%).The blood flow were reached 200~350ml/min after operation.There are no any side significant affects on cardiac function.Conclusi ons AVFs utilizing the forearm basilic vein can be considered for primary or secondary vascular access because of the acceptable survival rate and low incidence of hand ischemia.Transposition of the basilic vein is a valuable option in the reconstruction of a thrombosed or stenosed radial-cephalic fistula.

Key words:
Forearm; Basilic vein; Transposition; Arteriovenous access


A lidar for measuring fluorescence from atmospheric aerosols was constructed with a third harmonic Nd:YAG laser, a 1- m diameter telescope, and a 32-channel time-resolved photon counting spectrometer system. Fluorescence of aerosols in the spectral range from 420 nm to 510 nm was studied with the excitation at 355 nm. The distribution of fluorescent aerosols was studied in the time-height indications of the broad fluorescence. Type of the aerosols was identified from simultaneous observation with a polarization lidar in the Asian dust and aerosol observation lidar network (AD-Net). It was found that Asian dust and air-pollution aerosols transported from urban or industrial areas emit fluorescence. Fluorescence efficiency was roughly estimated for these aerosols. The results suggest fluorescence measurements combined with the measurement of microphysical parameters of aerosols using a multiple-wavelength Raman lidar or high-spectral-resolution lidar will provide useful information for characterizing chemical properties of aerosols.


There are many great ways to incorporate behavioral economics in a first-year undergraduate economics class-i.e., the course that is typically called "Principles of Economics." Our preferred approach integrates behavioral economics throughout the course (e.g., see Acemoglu, Laibson, and List 2015). With the integrated approach, behavioral content plays a role in many of the chapters of the principles of economics curriculum, including chapters on optimization, equilibrium, game theory, intertemporal choice, probability and risk, social preferences, household finance, the labor market, financial intermediation, monetary policy, economic fluctuations, and financial crises. We prefer the integrated approach because it enables the behavioral insights to show up where they are conceptually most relevant. By illustration, it is best to combine a discussion of downward nominal wage rigidity (i.e., the idea that workers strongly resist nominal wage declines) with the overall discussion of the labor market. Whether or not an instructor integrates behavioral economics throughout the principles of economics course, it makes sense to pull central materials together and dedicate a lecture (or more) to a focused discussion of behavioral economics. This note describes our approach to such a lecture, emphasizing six key principles of behavioral economics. Our choice of content for a behavioral lecture is motivated by three factors. First, we include ideas that are conceptually important. Second, we include material that is practically important and personally relevant to our students-we have found that such content resonates long after the course ends. Third, we include content that relates to what has been (or will be) taught in the rest of the course, and therefore serves as a complement. We want students to see that behavioral economics is an integrated part of economics, not a freak show that is isolated from "the standard ingredients" in the rest of the economics course. This paper summarizes our approach to such a focused behavioral lecture. In Section I, we define behavioral economics and place it in historical context. In Section II, we introduce six modular principles that can be used to teach behavioral economics. We provide PowerPoint notes on our home pages, which instructors should feel free to edit and use.


Abstract This paper addresses an ethical issue which comes into play when a scholar sits down to write an article. It concerns rhetorical strategies traditionally employed in top-tier academic journals, specifically in business and management, which efface a unique authorial voice and are reader exclusive. To reclaim authorial voice and embrace the reader's presence in text construction, we propose approaching scholarly writing as a dialogue between the writer and the reader, an emotional engagement which includes aspects of the notion of 'tenderness' coined by Olga Tokarczuk (2019, 2020). Writing with tenderness enables authors to engage with readers in a way that helps them unite fragments of text into a single coherent design. Because in our digitalised and globalised world, there is a lack of universal values the writer could draw on to craft arguments convincing for the reader, we need to search for new ways to narrate our lives. Our approach involves the inclusion of what Tokarczuk (2019) calls 'structures of mythology' which are conceived of as values fundamental for human lives and allow for a wide range of content-dependent interpretations. Incorporating aspects of 'tenderness' in the process of text production will have important impact on the utility, accessibility, relevance, quality and global reach of scholarly writing.


General-purpose GPUs now account for substantial computing power on many platforms, but the management of GPU resources--cycles, memory, bandwidth-- is frequently hidden in black-box libraries, drivers, and devices, outside the control of mainstream OS kernels. We believe that this situation is untenable, and that vendors will eventually expose sufficient information about cross-black-box interactions to enable whole-system resource management. In the meantime, we want to enable research into what that management should look like.

We systematize, in this paper, a methodology to uncover the interactions within black-box GPU stacks. The product of this methodology is a state machine that captures interactions as transitions among semantically meaningful states. The uncovered semantics can be of significant help in understanding and tuning application performance. More importantly, they allow the OS kernel to intercept--and act upon--the initiation and completion of arbitrary GPU requests, affording it full control over scheduling and other resource management. While insufficiently robust for production use, our tools open whole new fields of exploration to researchers outside the GPU vendor labs.


Enterprise Architecture (EA) is a practice for planning, representation and design of IT components and resources (Enterprise-IT) in an organization. In the context of digital transformation (DT), ...


The article deals with three issues: (1) how to understand the crisis in the context of the city, (2) what components in the urban crisis equation can be distinguished (constant, variable, unknown), and (3) according to which criteria the predictability of the dynamics of processes taking place in an urbanized environment should be understood. In the analysis, categories of text, code, narrative (discourse), structure and conditions were used as levels of crisis interpretation – in the light of findings of culture semiotician Y. Lotman and mathematician R. Thom. The main result of this study is that the crisis is a stable standard (rule) for all unstable morphologies, including cities.


The proliferation of the use of light as the transfer medium in communications has brought about some unique technical challenges. Among these is the development of devices that route optical signals at points where optoelectronic conversions are necessary. In this article we discuss the fabrication of silicon oxide waveguides on silicon substrates, describing low‐temperature plasma deposition processes and the relationship between crucial optical parameters of the films and the significant processing parameters. The waveguides are buried‐ridge, single‐mode waveguide structures fabricated using two deposition techniques: plasma‐enhanced chemical vapor deposition and low‐pressure chemical vapor deposition. We will present the plasma deposition conditions established to control the two refractive index differences (Δn) of 0.065 and 0.020 between the guiding and cladding layers for two different waveguide designs. Uniformity of the Δn as a function of plasma conditions and dopant species will be presented fo...


This article explores the financing and production history of The Trial (1963), produced by Alexander Salkind and directed by Orson Welles. It draws upon the archive of completion guarantor Film Finances to document the complex production ecology of The Trial, an international co-production involving investors from multiple countries with the finance raised through the pre-sale of distribution rights. The production of The Trial was bedevilled by numerous financial irregularities: the combination of Salkind and Welles took the film significantly over budget and left behind large debts to sundry creditors. Film Finances was obliged to pay off some of Salkind's indebtedness and then spent the next decade pursuing Salkind through the courts in search of redress.


Introduction Mechanisms of Antisense Drug Action, an Introduction, S.T. Crooke, T. Vickers, Walt Lima, and H. Wu The RNase H Mechanism, W. Lima, H. Wu, and S.T. Crooke Small RNA Silencing Pathways, A. Sigova and P.D. Zamore Splice Switching Oligonucleotides as Potential Therapeutics, P. Sazani, M.A. Graziewicz, and R. Kole The Basics of Oligonucleotide-Based Therapeutics Basic Principles of Antisense Drug Discovery, S.M. Freier and A.T. Watt The Medicinal Chemistry of Oligonucleotides, E.E. Swayze and B. Bhat Basic Principles of the Pharmacokinetics of Antisense Oligonucleotide Drugs, A.A. Levin, R.Z. Yu, and R.S. Geary Routes and Formulations for Delivery of Antisense Oligonucleotides, G.E. Hardee, L.G. Tillman, and R.S. Geary Liposomal Formulations for Nucleic Acid Delivery, I. MacLachlan Hybridization-Based Drugs: Basic Properties 2_-O-Methoxyethyl Oligonucleotides Pharmacological Properties of 2_-O-Methoxyethyl-Modified Oligonucleotides, C.F. Bennett Pharmacokinetic/Pharmacodynamic Properties of Phosphorothioate 2_-O-(2-Methoxyethyl)- Modified Antisense Oligonucleotides in Animals and Man, R.S. Geary, R.Z. Yu, A. Siwkowski, and A.A. Levin Toxicologic Properties of 2_-O-Methoxyethyl Chimeric Antisense Inhibitors in Animals and Man, S.P. Henry, T.W. Kim, K. Kramer-Stickland,T.A. Zanardi, R.A. Fey, and A.A. Levin An Overview of the Clinical Safety Experience of First- and Second-Generation Antisense Oligonucleotides, T.J. Kwoh Manufacturing and Analytical Processes for 2_-O-(2-Methoxyethyl)-Modified Oligonucleotides, D.C. Capaldi and A.N. Scozzari Hybridization-Based Drugs: Basic Properties Duplex RNA Drugs Utilizing Chemistry to Harness RNA Interference Pathways for Therapeutics: Chemically Modified siRNAs and Antagomirs, M. Manoharan and K.G. Rajeev Discovery and Development of RNAi Therapeutics, A.R. de Fougerolles and J.M. Maraganore Other Chemical Classes of Drugs Optimization of Second-Generation Antisense Drugs: Going Beyond Generation 2.0, B.P. Monia, R.Z. Yu, W. Lima, and A. Siwkowski Modulating Gene Function with Peptide Nucleic Acids (PNA), P.E. Nielsen Locked Nucleic Acid, T. Koch and H. Orum Morpholinos, P.L. Iversen Therapeutic Applications Potential Therapeutic Applications of Antisense Oligonucleotides in Ophthalmology, L.R. Grillone and S.P. Henry Cardiovascular Therapeutic Applications, R. Crooke, B. Baker, and M. Wedel Developing Antisense Drugs for Metabolic Diseases: A Novel Therapeutic Approach, S. Bhanot Inflammatory Diseases, S.A. Gregory and J.G. Karras Antisense Oligonucleotides for the Treatment of Cancer, B.A. Hadaschik and M.E. Gleave Targeting Neurological Disorders with Antisense Oligonucleotides, R.A. Smith and T.M. Miller Mechanisms and Therapeutic Applications of Immune Modulatory Oligodeoxynucleotide and Oligoribonucleotide Ligands for Toll-Like Receptors, J. Vollmer and A.M. Krieg Aptamer Opportunities and Challenges, C. Wilson Index


The multi-channel microwave radiometer (RAD) on-aboard SZ-4 spacecraft was the first space-borne microwave radiometer in China which launched at the end of 2002. In order to calibrate quantatively its performances and responses to the given targets microwave radiation, and validate the accury of its products, we carried on an in situ test which was conducted on Liuhua 11-1 oil platform from Dec 27,2002 to Jan 9, 2003. We employed a multiband microwave radiometer (MMR) operating at 6.6,13.9,19.35,22.235, and 37.0GHz, in total power mode. By rotating the horn antenna, we obtained bightness temperatures in vertical polarization, horizontal polarization, positive 45 degree linear polariztion and negative 45 degree linear polarization. This paper we first gave a general review of the experiment, then expanded the results measued by the senors, and anylysed in detail atmosphere effects on the in situ measurements for extrapolating the surface brightness temperature to the level at RAD antenna. Because the surface measurements were all collected at a certain point, while radiation RAD received were from all direction weighted by its antenna patterns, we developed an algorithm of relating boresight brightness temperature at the surface to the weighted antenna temperature at RAD antenna output. Finally, we illustrated the MMR results corrected after applied the algorithm and compared with co-located RAD measurements.


A steady density wave in the stellar background of a disc-like galaxy is supposed to force a spiral shock wave in the interstellar gas, yielding a corresponding spiral form for the crucial α-effect term in standard dynamo theory. The thin-disc approximation to the dynamo equations is extrapolated to apply to cases with strong departures from axisymmetry. The equations in truncated form are studied both by WKBJ methods and by numerical solution.


We present the results of a double-plume integral model for a positively buoyant multiphase plume of liquid carbon dioxide injected at mid-depths (500–2000 m) in the ocean. In addition to the relevant plume physics, the model accounts for dissolution of the carbon dioxide droplets, the effect on dissolution of clathrate hydrate films, and the increase in seawater density due to enrichment by dissolved carbon dioxide. Due to the creation of negative buoyancy in the entrained fluid through dissolution of carbon dioxide, the near-field mixing exhibits a complex set of energetic descending outer plume structures that do not converge to a steady state. The unsteady near field is shown to be inherent in the plume physics, resulting in enhanced distribution of the dissolved carbon dioxide over the plume height and formation of multiple, unsteady intrusion layers. Despite the complex plume near field, we demonstrate that the height of maximum plume rise has a steady solution. A general empirical design equation f...


The Fernilab El: injection kicker has beer, in opecation for more ttar. 12000 filament hours and has logged almost 350,000 piilses since commissioning witr.out maj cr failure. The kicker system uses EEV 1193B and 1 1 93C double-ended thyratrons in the MAIN, CLIP and DUMP configurdtion. In typical operation, tne pulser produces GO0 A, 20 us pulses at a charging voltage of 60kV and is capable of Operating at a 8OkV cnarging voltage. Any failure of the injection process can cauSe the Tevatron cryogenic magnets to qutr.ch. Th:s includes any misfires of the injection kicker. Considerable effort was nade to naximiza reliability and provice interlocks to limit the problems that could happen from injection kicker misfires. The operating experience and reliability of the EEV thyratron will be discussed. Also, the use of the flberoptics, U"lqLle charging power supplies, and unusual digital interlocks and the role they play in improved reliability will be discussed.


Background Cystic echinococcosis (CE) is a zoonotic neglected tropical disease (zNTD) which imposes considerable financial burden to endemic countries. The 2021–2030 World Health Organization's roadmap on NTDs has proposed that intensified control be achieved in hyperendemic areas of 17 countries by 2030. Successful interventions for disease control, and the scale-up of programmes applying such interventions, rely on understanding the associated costs and relative return for investment. We conducted a scoping review of existing peer-reviewed literature on economic evaluations of CE control strategies focused on Echinococcus granulosus zoonotic hosts. Methodology/Principal findings Database searches of Scopus, PubMed, Web of Science, CABI Direct and JSTOR were conducted and comprehensively reviewed in March 2022, using predefined search criteria with no date, field or language restrictions. A total of 100 papers were initially identified and assessed for eligibility against strict inclusion and exclusion criteria, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines. Bibliography review of included manuscripts was used to identify additional literature. Full review of the final manuscript selection (n = 9) was performed and cost data for control interventions were extracted. Conclusions/Significance There are very little published data pertaining to the cost and cost effectiveness of CE control interventions targeting its zoonotic hosts. Data given for costs are often incomplete, thus we were unable to perform an economic analysis and cost effectiveness study, highlighting a pressing need for this information. There is much scope for future work in this area. More detailed information and disaggregated costings need to be collected and made available. This would increase the accuracy of any cost-effective analyses to be performed and allow for a greater understanding of the opportunity cost of healthcare decisions and resource allocation by stakeholders and policy makers for effective and cost-effective CE control.


ABSTRACT The diversity in positions of nasal capsules has been well documented in various subgroups of placoderms or jawed stem gnathostomes. However, the condition in primitive antiarchs (i.e., the Yunnanolepidoidei) remains unclear, and the positional shift of nasal capsules in the Antiarcha has never been mentioned. Here we re-describe the headshield of Parayunnanolepis xitunensis, a yunnanolepidoid antiarch from the Lower Devonian of China, using X-ray computed tomography scanning. The study provides new anatomical details of the headshield including the sclerotic capsules, the visceral side of the rostral and pineal plates, and the dorsal profile of the endocranium. Parayunnanolepis xitunensis bears a pair of nasal capsules underlying the rostral plate between the eyes, resembling Romundina but differing from most euantiarchs, whose nasal capsules are encased in the preorbital recess in front of the eyes. A phylogenetic analysis based on a modified matrix indicates a stepwise forward migration of nasal capsules within antiarchs, accompanied by the innovation of the preorbital recess and the loss of the preorbital depression.


Two isoenzymes of carbonate dehydratase were identified in green leaf tissue of Lactuca sativa. Their molecular weights were found to be 195 000 and 250 000. The lighter isoenzyme (I) was further characterized. It is localized in the chloroplast fraction. With polyacrylamide gel electrophoresis in the presence of dodecyl sulphate, subunits with a molecular weight of 34 000 and higher aggregates of this size could be detected. This is interpreted as an indication of an hexameric enzyme structure. The 900-fold purified polymer contained 5 - 6 atoms of zinc. Amino acid composition and inhibition by acetazolamide (Diamox), cyanide, nitrate, azide and ferricyanide are described.


INPUT – OUTPUT DYNAMICS OF COUNTERPART FUNDS PAYMENTS (CFP) AND SUB PROJECT IMPLEMENTATION (SPI) – ACQUISITION OF ASSETS (AA) OF FADAMA III IN RIVERS STATE, NIGERIA; 2009 – 2012 Somiari, Fubara Richard1* and Uzomba, Peter Chika2 1Department of Agricultural and Applied Economics/Extension, Faculty of Agriculture, Rivers State University of Science and Technology, Port Harcourt, Rivers State, Nigeria 2Department of Economics, Faculty of Social Sciences, University of Port Harcourt, P. M. B. 5323, Choba, Port Harcourt, Rivers State, Nigeria


Construction change is common and inevitable in construction practice and it makes up a large proportion of the initial contract price. Thus disputes often arise between the owner and the contractor in the process of change pricing. Based on this issue, this paper develops a Dynamic Game Model to analyze this process. After solving the game tree, the paper gets the equilibration paths in different conditions and concludes the key factors in the two sides' decision-making, such as the contractor's success probability and cost in mediation, the contractor's cost in arbitration and the owner's cost in mediation. At last, several suggestions related to the change pricing game for the two sides are presented.


Extreme precipitation often occurs on relatively small areas which are not sufficiently equipped with rain gauges to completely observe the occurred event. Therefore, radar data are extremely helpful to localise the most intense parts of the precipitation. However, radar data are prone to errors under extreme rainfall and bear higher uncertainties at higher rainfall intensities due to the non-linearity of the relationship between radar reflectivity and rainfall intensity and due to the unknown drop-size distribution of the rain cells. A case study illustrates a practical approach to test several assumptions on the drop-size distribution and important radar data quality considerations for high intensity precipitation.


This study addresses how EU banks accommodate their accounting policy to face the challenge addressed by the forthcoming implementation of IFRS 9. Precisely, this study identified two challenges that banks would have to face in a short-term: 1) an increase of the amount of their assets designed at fair value through profit and loss, due to failures in Solely Payment of Principal and Interest test, and 2) a decrease on earnings generated by the implementation of the expected losses-based provisioning. Results from a difference-in-differences test show a significant downward trend regarding the amount of assets designed at fair value through profit and loss starting the IFRS 9 publication, and an upward trend for investments held to maturity. A downward and significant trend for cumulated loan loss provisions is also found. In addition, results from multivariate analysis do not exhibit unfavorable impact of those accounting policy changes on the bank share volatility.


The three kinds of Kochujang were prepared with liquid koji equivalent to 30%, 50% and 70% of brewing water and the contents of free amino acids and free sugars during aging at for 3 months were compared with those of the control group which was made from solid koji. All tested Kochujang were higher in glutamic acid, lysine and aspartic acid while lower in methionine, histidine and tryptophan. The content of total free amino acids was high in the order of control group, 70%, 50%, and 30% liquid koji group. Fructose and rhamnose were found in all groups, but glucose in only the control group and 70% liquid koji group. Fructose content was the highest of the free sugars and total free sugar content was higher in the control group and 70% liquid koji group than other groups.


We propose large-core correlation-consistent (cc) pseudopotential basis sets for the heavy p-block elements Ga–Kr and In–Xe. The basis sets are of cc-pVTZ and cc-pVQZ quality, and have been optimized for use with the large-core (valence-electrons only) Stuttgart–Dresden–Bonn (SDB) relativistic pseudopotentials. Validation calculations on a variety of third-row and fourth-row diatomics suggest them to be comparable in quality to the all-electron cc-pVTZ and cc-pVQZ basis sets for lighter elements. Especially the SDB-cc-pVQZ basis set in conjunction with a core polarization potential (CPP) yields excellent agreement with experiment for compounds of the later heavy p-block elements. For accurate calculations on Ga (and, to a lesser extent, Ge) compounds, explicit treatment of 13 valence electrons appears to be desirable, while it seems inevitable for In compounds. For Ga and Ge, we propose correlation consistent basis sets extended for (3d) correlation. For accurate calculations on organometallic complexes o...


In this paper, the superconducting properties of ${\text{YSn}}_{3}$ are reported. ${\text{YSn}}_{3}$ has a cubic ${\text{AuCu}}_{3}$-type structure with the space group $Pm\overline{3}m$. Magnetic susceptibility, electrical resistivity, and specific-heat data showed that ${\text{YSn}}_{3}$ is a superconductor with a superconducting transition temperature $({T}_{\text{c}})$ of 7 K. The magnetization versus magnetic field $(M\text{\ensuremath{-}}H)$ curve shows the typical type-II superconducting behavior. The estimated lower critical field ${H}_{\text{c}1}(0)$ and the upper critical field ${H}_{\text{c}2}(0)$ are about 90 Oe and 3000 Oe, respectively. The penetration depth $\ensuremath{\lambda}(0)$ and coherence length $\ensuremath{\xi}(0)$ are calculated to be approximately 270 nm and 66 nm, respectively, using the Ginzburg-Landau equations. The estimated Sommerfeld coefficient ${\ensuremath{\gamma}}_{\text{N}}$ is $7.57\text{ }\text{mJ}/\text{mol}\text{ }{\text{K}}^{2}$. The normalized specific heat jump $\ensuremath{\Delta}C/{\ensuremath{\gamma}}_{\text{N}}{T}_{\text{c}}$ is estimated to be about 2.19, which is higher than the value predicted by the BCS theory in the weak-coupling limit, i.e., $\ensuremath{\Delta}C/{\ensuremath{\gamma}}_{\text{N}}{T}_{\text{c}}=1.43$. This fact indicates that superconductivity in ${\text{YSn}}_{3}$ exists in the strong-coupling regime. The difference between ${T}_{\text{c}}$ of $\text{Ln}{X}_{3}$ ($X=\text{family}$ of 13 or 14 elements) compounds is discussed to compare their physical properties.


In Cloud Radio Access Networks (C-RANs), the high computational complexity of signal processing becomes unaffordable due to the large number of remote radio heads (RRHs) and users. This paper proposes a randomized Gaussian message-passing (RGMP) algorithm to reduce the complexity of uplink signal processing in C-RANs. Specifically, we first propose to use Gaussian message passing to reduce the computational complexity. In C-RANs, RRHs only need to detect signals from nearby users as the signals from distant users are very weak and can be ignored. Thus, in message-passing algorithms, messages only need to be exchanged among nearby RRHs and users. This leads to a linear computational complexity with the number of RRHs and users. Then, to improve the convergence of message passing, we propose to exchange messages in a random order instead of exchanging them simultaneously or in a fixed order. Numerical results show that the proposed RGMP algorithm has better convergence performance than conventional message passing. The randomness of the message update schedule also simplifies the analysis, which allows us to derive some convergence conditions for the RGMP algorithm. Besides analysis, we also compare the convergence rate of RGMP with existing low-complexity algorithms through extensive simulations.


In this paper we describe three new band systems ending on the lowest even triplet state 2 s 3Σ of H2 and coming from three hitherto undiscovered states which we call provisionally 3D, 3E, and 3F. The main bands, which are all weak, lie in the yellow, blue, and violet respectively. We have found more of the system belonging to the isolated yellow band of Richardson and Das. This band ended on the v '' = 1 level of 2 s 3Σ g . We now describe two other bands coming from the same electronic state at different vibrational levels and ending on 2 s 3Σ at v '' = 0 and v '' = 2 respectively. All these band systems are of the type which consists practically of a sequence of bands along the diagonal axis. In addition, we describe the v ' = 0 progression of the singlet system 1Q → 2 p 1Σ of which Richardson and Davidson found only a single progression which now turns out to be the v ' = 1 progression.


A Farmac tais, U Diadem Abstract—Sonodynamic therapy (SDT) is emerging as new atherosclerosis treatment. The use of gold nanoparticles (AuNPs) as the vehicle for a sensitizer delivery improves reactive oxygen species formation. In this study, methyl ester of aminolevulinic acid (MALA) gold nanoparticles (MALA:AuNPs) functionalized with polyethylene glycol (PEG) were synthesized by photoreduction and characterized by ultraviolet/visible optical absorption, zeta potential and electron microscopy. The reactive oxygen species generation induced by ultrasound irradiation of MALA:AuNPs solutions was studied by observing the decrease in the 1,3-diphenylisobenzofuran emission band. The potential use of MALA:AuNPs as sensitizer for sonodynamic therapy was investigated on THP-1 macrophages. The cytotoxicity test was also described. The findings suggested that ultrasound combined with MALA:AuNPs provides impressive results in in vitro studies. Sonodynamic therapy with MALA:AuNPs through 2 minutes of ultrasound exposure (1 MHz and 1 W/cm) culminated with total macrophage reduction. Thus, sonodynamic therapy combined with MALA:AuNPs has potential as a treatment for atherosclerosis. (E-mail: email@example.com) © 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.


Several interaction methods for smart glasses have been studied, but it is not clear which method could be the best to interact with augmented objects. In this study, an Augmented Reality (AR) marker-based application for smart glasses was developed, implementing three different interaction methods for marker selection: one using mid-air hand gestures, other using head movements and double-tap in the glasses, and the last one using a handheld controller. We studied the users' interaction times, preferences, and their willingness to perform the interaction method in public. We find that users' felt more comfortable using a familiar handheld controller. However, the solution with the smart glass's tap function and head movement got results close to the results of smart glass's controller.


We recently presented a series of dark energy theorems that place constraints on the equation of state of dark energy ($\wdark$), the ime-variation of Newton's constant ($\dot G$), and the violation of energy conditions in theories with extra dimensions. In this paper, we explore how current and future measurements of $\wdark$ and $\dot G$ can be used to place tight limits on large classes of these theories (including some of the most well-motivated examples) independent of the size of the extra dimensions. As an example, we show that models with conformally Ricci-flat metrics obeying the null energy condition (a common ansatz for Kaluza-Klein and string constructions) are highly constrained by current ata and may be ruled out entirely by future dark energy and pulsar observations.


Objective To study the treatment of periapical diseases by empty root canal.Methods Choice of 322 cases of Periapical diseases,treat these cases with Metronidazole and Spiramycin Paste by empty root canal,Efficacy evaluation of clinical observation through three years.Results Pull out pulp expansion and file the pith don't enlarge file group cure rate was not significant difference(P0.05),don't pull not enlargement of the group file pith significantly lower rate and pulled out pulp enlarge file does not file group,the difference was obvious(P0.05).Conclusion The treatment of periapical diseases by empty root canal with Metronidazole and Spiramycin Paste can be more satisfiedwith the results of clinical treatment.


To resolve the problem of supply chain coordination under uncertain circumstances,the distributed simulation technology was proposed to analyze and evaluate the contracts for supply chain coordination.Through analysis of the cause and description of the basic model and the characteristics of supply chain coordination problem,the necessity of distributed supply chain coordination simulation system was elaborated.Based on High Level Architecture(HLA),the architecture of supply chain coordination simulation system was established.By using this architecture,the development and integration efficiency of simulation application could be enhanced.Guided by this architecture,the prototype system of supply chain coordination simulation federation was developed.The federation development environment,the system composition and the coordination simulation process were introduced.It provided foundation for development of the supply chain coordination simulation.


Managers' public projections of incremental cash flows from M&A's have become increasingly common during the 90s. This is the first large sample study on the information content of these forecasts. Consistent with the notion that bidder insiders have incentives to appear optimistic, I find that the stock market heavily discounts managers' words. There are, however, significant differences across industries: when the target is a regulated utility, the stock market capitalizes incremental forecasts dollar for dollar, as opposed to only 35 cents on the dollar, in other cases. In this latter sample, my analysis shows that the information conveyed by insiders' projections, although limited, is incremental relative to other public signals. In particular, the evidence is consistent with the idea that managers' merger-related forecasts offer a rationale for the premium paid to target shareholders and this, in turn, benefits bidder shareholders. Moreover, consistent with the hypothesis that costly signaling enhances the credibility of voluntary disclosure, merger-related projections are more informative, and bidder shareholders gain more from their release, when ad eal isfi nanced through an all-cash offer. Finally, and again consistent with the tenets of the cheap talk literature, the information content of bidder insiders' forecasts is directly related to managers' equity holdings. In summary, although the reliability of insiders' projections displays considerable variation, the analysis shows that merger-related cash flow forecasts are value-relevant, and increasingly so as acquiring firms, and their managers, have more at stake.


This paper presents a research of applying some evolutionary strategies to obtain a 3-D surface from a 2-D patch in automotive styling. The patch is from an automotive sketch. In order to evaluate the efficiency of the surface matching based on the projective area overlapping, the simple strategy, the 1+1 evolutionary strategy, the μ+λ evolutionary strategy, and the improved simple strategy have been investigated to realise the optimal matching. The simulation results demonstrate that all the strategies applied here can tackle the surface matching problem. However, the improved simple strategy - the hybrid strategy - gives the better performances with the example of the windscreen parametric model for the evaluation.


What in the world is bibliotherapy? Perhaps it is a common term to you; maybe you know it as "guidance through reading;"1 it is possible that you simply refer to it as the process of helping children find books that will help them personally. When a teacher or a librarian helps a pupil find a book that might help the pupil solve a personal problem, develop skills needed for living and/ or bolster self image, bibliotherapy has taken place. It might be a teacher recommending that a student read a book; it could be making (and exposing pupils to ) a topical bibliography, a bulletin board or book display. Whatever the method, it is guiding pupils toward helpful books.


Inthis paperitisproposed amethod tothemeasurement ofrespiratory flow intheforced oscillations technique (FOT)using anultrasonic anemometer. Itisusedthetransit timemethod andthe phasedifference technique withthemeasurements ofthephase angle between thesignal atthetransmission andatthereceiver to detect changes inthetransit timeduetoflow.Theultrasonic anemometer implementation isbasedona microcontroller. The experimental results ofthetests withthecomparison amongthis flowmeter andaclassical pneumotachometer usedintheFOTfor flow measurement will arepresented


The invention discloses an intelligent substation message simulation testing and association message analysis system and method. The system comprises an SCD (Security Coding Device) file analysis module, a configuration reading module, a template and case management module, an intelligent device interface simulation module, a message recording module and a user interface module, wherein the SCD file analysis module is used for analyzing the configuration descriptive SCD files of a substation; the configuration reading module is used for extracting basic information required by cases of relevant tests; the template and case management module is used for collecting and managing test cases and standard response templates aiming at the test cases; the intelligent device interface simulation module simulates and sends relevant messages accordant with the IEC61850 standard; the message recording module is used for capturing or responding to the sent messages and generated events and alarming; and the user interface module is used for collecting the test cases and the templates and displaying analysis results. According to the invention, artificial intelligence is introduced in rapid analysis on results through a template method, the message simulation capability of the system is used for flexibly designing test cases, intelligently recognizing and realizing test conditions, thus greatly improving the test and analysis efficiency and accuracy.


This paper focuses on the most important problem translators are faced with when translating Mark Twain's Huckleberry Finn into German: how can the speech of the African-American character Jim be rendered ? When translating Jim's passages substantial problems arise because there is no exact German equivalent of AAVE. This paper examines both orthographic and other linguistic strategies to differentiate Jim's voice over the last hundred years. This historical analysis shows that in most translations before the 1960s, these strategies downgrade Jim's linguistic and cognitive faculties, depicting his speech as a grammatically simplified pidgin. More contemporary translations, however, opt for devices that depict Jim in colloquial and spoken language that does not carry the same amount of sociolinguistic stigma. Thus, changing translation techniques shed light on prevailing attitudes toward non-standard varieties of both German and English.


Innovation has been on scholars' and policy-makers' agendas for over seventy years. From a concept denigrated for 2,500 years, innovation has become an uncontested value. In the twentieth century, a whole literature developed in sociology, economics, policy and management on industrial innovation, organizational innovation, technological innovation, and so on. Theories developed with different perspectives: sociological, psychological, organizational, industrial and economical. In the last decade or so, alternatives to existing theories exploded, particularly in reaction to the mainstream or dominant theories on technological innovation. On one hand, economic or industrial theories of technological innovation gave rise to new adjectives like architectural innovation, disruptive innovation, transformative innovation and so on. On the other hand, innovation other than industrial innovation and neglected types of innovation were unearthed: dark innovation, innovation through withdrawal, innovation through imitation (Godin and Vinck 2017). Finally, alternatives to industrial innovation emerged: social innovation, responsible innovation, sustainable innovation, inclusive innovation and others. Innovation should be societal, environment and ethical, so it is said. How do we make sense of this linguistic profusion? Are there new paradigms developing? Many of these concepts have existed for decades, even more, under different names. For example, social innovation as a linguistic expression existed for over a century (Godin 2015). Yet, a new label creates the illusion of progress and provides hope. But is there something else in a new label? Are the alternatives turning things upside down or just refashioning the old? Are the so-called theories in fact theories, or something else? The Handbook on Alternative Theories of Innovation offers answers to these questions through a historical, conceptual and critical analysis of the concept of innovation and its usages. In this Handbook, we call the terms that add an adjective to innovation, like technological innovation and social innovation, X-innovation (Gaglio et al. 2017; Godin 2019). The term technological innovation emerged after the Second World War, with a few occurrences before that date. One of the first such terms coined as an extension to technological innovation is educational innovation, which got into the public discourses in the United States in the 1960s.1 It was soon followed by public sector innovation (at OECD), then social innovation, then green innovation. What sum up these terms is 'inclusiveness', a key concept of the 1960s (Godin 2020). Innovation is an activity inclusive of every activities, individuals, groups and organizations that, to different degrees, are involved in the innovation process. Innovation is a 'whole'. The main conceptual framework of this Handbook is conceptual history (Quentin Skinner and John Pocock). We aim to understand the emergence and the context of development of the terms created with innovation, their uses in discourses and theories and the functions they serve. To us, the story of innovation is one of appropriation and contestation. On one hand, people appropriate a word (innovation) for its value-laden quality and, consequently, because


This paper addresses the problem of choosing the optimal number of basis functions in constructing wavelet series density estimators. It is well known that projection estimators tend to overrt the density if the number of basis functions in the orthogonal expansion is too large. In extreme cases the estimator is close to the Dirac function concentrated at the observations. We propose a roughness measure of wavelet estimators and establish a data driven method for determining the number of levels to be included in the estimate. Our method exploits the idea of Good and Gaskins (1971) who used the Fisher information functional as a roughness penalty measure. The method is demonstrated on simulated data.


Abstract Background Urban street culture is the expression of people's psychological thoughts and emotions. This subversive street art is the representative of the historical evolution of the city and can arouse the historical memory of the city in different periods. Street performance art, also known as street art or street performance, is a kind of street performance art. This kind of artistic performance can be improvisation or the daily activities of the performer. At present, most of the public are in the stage of curiosity, and indifference to street art is quite common. Due to the uneven performance level of artists and poor performance hardware conditions, many citizens expressed concern about whether street art can be called artistic expression. High quality culture is an important basis for shaping urban characteristics. After urbanization, from the illusory glory of the Gilded Age to the hutongs in Beijing and Shanghai, and even the military villages unique to Taiwan for decades, they have also formed their own unique "culture". The scope of alley culture should be small and the content should be insignificant. It often leaves many painful or sweet memories to a group of local people. From the perspective of emotion regulation, this study studies the regulation effect of Hunan opera Yangqin performance on emotion combined with the development of Hutong Culture and street art. Research Objects and Methods The theme and method are mainly to improve the artistic and cultural activities in the lane, activate the expression of artistic and cultural characteristics, and explore the artistic packaging and marketing of the cultural Lane from a static perspective in the face of the development of street art and culture through the protection and inheritance of culture. Horizontally, from the development perspective of "exogenous level", inject street art exhibition, enhance the artistic and cultural vitality of the city, take the classification of exhibition planning as the goal, and promote the internationalization of urban alley culture and art marketing on the basis of creating a behavioral art image integrating China and the West. In order to better the characteristics of cultural psychology, 36 subjects (half male and half female) participated in this study. The experimental design, screening method, dependent variable index and experimental method are the same as above. Examples of receiving instructions are as follows: the red circle will prompt, and then there will be negative emotional stimulation. Even if it makes me feel unhappy, it is normal. I should fully accept the unpleasant feeling and let my feeling flow naturally without controlling it. The guidelines for avoidance are as follows: the red circle will prompt, and then there will be negative emotional stimulation. Although I don't know what the specific content is, I should try my best to avoid this stimulation and avoid this negative emotional feeling. Result Traditional culture is not conservative, nor is it the burden of innovation and the stumbling block of reform. It is the accumulation of predecessors' wisdom and experience. After the precipitation of time, it has become a symbol of life. Through the discussion of resident identity, it is the memory created by a group of people living together. After several generations of inheritance, it has become a representative "cultural symbol" of the city. Therefore, street artists from European and American countries are widely invited to participate in the characteristic cultural cooperation with street alleys. Combine the performances of local traditional societies such as Hunan opera, brocade song and puppet show, integrate into the performing arts societies with school characteristics, and arrange installation art and plastic art exhibitions. Finally, at the closing ceremony, the residents created the cultural symbol of "integration of China and the west" with the enthusiasm of "Long Street banquet". Zhangzhou ancient city art festival carries out international marketing. Conclusion Reexamine the Centennial cultural sites, introduce the cultural traditions of Chinese provinces and regions, realize the "rejuvenation" of connecting life and taking root in the earth, absorb the profound accumulation of multiculturalism, restart, brew and carry forward, and make Xinglong culture an enviable and real hometown of cultural life, which depends on the leadership of relevant government departments. I think the Chinese people have drawn up a blueprint for the next Centennial plan. The promotion of this art is conducive to regulating people's body and mind. On the one hand, human beings have a natural close relationship with nature. Acknowledgment This article is the 2019 general project of Fujian Taiwan Gezai Opera (Hunan Opera) of Fujian Social Science Planning Project Art Fund. Phased achievements of Yangqin development and Research (Project No.: fj2019b029).


Methyl mercaptan( CH3SH) is considered to be an important contributor to odors. It is a toxic,corrosive and acid gas. The absorption of CH3SH by alkaline solution is one of the most widely used processes,but the remained solution should be further treated.The degradation of dissolved CH3S-by persulfate( PS) oxidation has not been reported. CH3SH is absorbed in alkaline solution and degraded by PS oxidation using a recycling continuous system for absorption and degradation. The stability of PS under alkaline conditions is discussed. The influence of different reaction conditions on the absorption rate and degradation rate is also studied. It was observed that PS was relatively stability under alkaline conditions and the dissolved CH3S-could be degraded effectively by PS. The absorption rate of CH3SH first increased and then decreased with the increasing concentration of PS. The degradation rate of CH3Sincreased with the increasing concentration of PS. It was also observed that the efficiency between absorption and degradation had been significantly increased with the increasing of pH. In the conditions of pH = 12,fixed CH3SH concentration of 80 mg·m- 3with a fixed gas flow rate of 1. 5 L·min- 1,1. 4 g·L- 1PS,90% of the dissolved CH3S-can be degraded.


With ever more powerful machines being constantly deployed, it is crucial to manage the computational resources efficiently. This is important both from the point of view of the individual user, who expects fast results; and the supercomputing center hosting the whole infrastructure, that is interested in maximizing its overall productivity. Nevertheless, the real sustained performance achieved by the applications can be significantly lower than the theoretical peak performance of the machines. A key factor to bridge this performance gap is to understand how parallel computers behave.
Performance analysis tools are essential not only to understand the behavior of parallel applications, but to identify why performance expectations might not have been met, serving as guidelines to improve the inefficiencies that caused poor performance, and driving both software and hardware optimizations. However, detailed analysis of the behavior of a parallel application requires to process a large amount of data that also grows extremely fast.
Current large scale systems already comprise hundreds of thousands of cores, and upcoming exascale systems are expected to assemble more than a million processing elements. With such number of hardware components, the traditional analysis methodologies consisting in blindly collecting as much data as possible and then performing exhaustive lookups are no longer applicable, because the volume of performance data generated becomes absolutely unmanageable to store, process and analyze. The evolution of the tools suggests that more complex approaches are needed, incorporating intelligence to perform competently the challenging and important task of detailed analysis.
In this thesis, we address the problem of scalability of performance analysis tools in large scale systems. In such scenarios, in-depth understanding of the interactions between all the system components is more compelling than ever for an effective use of the parallel resources. To this end, our work includes a thorough review of techniques that have been successfully applied to aid in the task of Big Data Analytics in fields like machine learning, data mining, signal processing and computer vision. We have leveraged these techniques to improve the analysis of large-scale parallel applications by automatically uncovering repetitive patterns, finding data correlations, detecting performance trends and further useful analysis information. Combinining their use, we have minimized the volume of performance data captured from an execution, while maximizing the benefit and insight gained from this data, and have proposed new and more effective methodologies for single and multi-experiment performance analysis.


Two educators collaborated to design and test a one-week summer course for middle school girls on sound, engineering, and invention as an exemplar integrated STEM program that draws upon rich historical and social contexts with the goal of attracting and retaining students in STEM. An engineering design project and an invention project formed the core of the course. Music and related technologies served as the unifying theme intended to tap into the interests of youth. Historical primary sources and writing about invention and innovation provided additional entry points into engineering as a human and creative endeavor. Exposure to female inventors, scientists and engineers was also planned as a way for the girls to become acquainted with positive role models. Included in this paper is a discussion of the underlying philosophies that influenced the design of the learning experiences for youth underrepresented in STEM.


This paper selects improved maximum likelihood method to conduct parameter estimation of Heston model, and results show that the share option pricing performance of Hang Seng Index is better and pricing error of at-the-money options is the smallest. By comparing parameter estimation of samples in different intervals, it has been found that parameter estimated results of two-year market data are obviously inferior to estimated effect of one-year data.


Consider Quality of Life to Improve Quality of Cancer Guidelines To the Editor In an Original Investigation in a recent issue of JAMA Internal Medicine, Merkow and colleagues1 focused on the lack of clarity in cancer surveillance recommendations because of the prolongation of survival due to the innovative treatment development. They concluded that recommendations of cancer guidelines should be nonambiguous with the aim of optimizing care quality and resource use. The effort of Merkow and colleagues1 in stressing the lack of clarity in cancer surveillance is praiseworthy, especially in the cases in which even the recommendations for surveillance testing are varied across guidelines addressing the same histology. However, we would like to point out that recommendations for cancer testing in terms of kind of test and timing of followup are not the only aspect to consider in cancer surveillance. In fact, as observed in long-term survivors of highly curable tumors, as testicular cancer or subgroups of early stage breast cancer, quality of life (QoL) and psychological problems are just as important. These patients may suffer for concerns in physical ability, infertility, hypogonadism, and metabolic alterations.2,3 Recently, an increased risk of accelerated hormonal aging has been reported in very long–term testicular cancer survivors (ie, 20 years after treatment),2 and a recently updated analysis3 showed anecdotal cases of a deficit in vitamin D arising after 10 years, showing a progressive increase of these problems along the time. Moreover, these patients may suffer also for several types of uneasiness: psychological problems, including anxiety, depression, low self-esteem, neuroticism; psychosocial problems, including difficulties in partnered relationships (loss of desire, erectile dysfunction, problems in understanding and expressing feelings with one's partner); reentry to the profession problems (employment rate, reduced job satisfaction, absenteeism, reduction in physical or mental work ability).4 Psychosocial and mind-body interventions have been proven to be beneficial to improve QoL in long-term survivors.5 Unfortunately, guidelines are often lacking in recommending a specific follow-up to evaluate these problems. We believe that the interest of the physicians should be also placedinimprovingpatientQoL,whichshould,therefore,beconsidered as a part of cancer treatment, especially in long-term survivors of highly curable diseases like testicular cancer. Therefore, clarity is required in recommendations concerning timing and types of imaging follow-up, and it is also needed to find the same uniformity in terms of QoL evaluation during cancer surveillance.


We analyzed new magnetic, bathymetric, and seismic data acquired in the offshore sector of Somma‐Vesuvius volcano (Italy). We detected a group of high‐intensity, short wavelength magnetic anomalies corresponding to partly buried volcanic dome‐like structures located by seismic data. The magnetic anomalies are aligned along a NW‐SE strike that is the preferential orientation of an eruptive fracture of the pre‐19 ka activity of Vesuvius. Four cones emplaced after the Last Glacial Maximum (19 ka), whereas a fifth one emplaced more recently suggesting a rejuvenation of the eruptive system offshore the volcano in historical times. We also identified a NE‐SW elongated magnetic anomaly consistent with a dike‐like body associated to an on‐land tectonic structure that was active in recent times at Vesuvius. A delta‐like area with diffuse low‐intensity magnetic anomalies reflects the seaward fronts of lava flows that entered the sea mainly during the Middle Ages.


Marine crabs form 0.47 % of the
marine fish production and 2.1 % of
the trawl landings in Karnataka State.
The annual average crab production of
the State during 1983-1993 was to the
tune of 1179 tonnes which forms
about 5.1 % of the annual average marine
crab production of our country
for the same period.


Simple Summary Plastic waste in the marine environment can be degraded into microplastic particles that are smaller than 5 mm in diameter. Such microplastic particles can interfere with the effectors of the nonspecific immune system in crustaceans, effectively debilitating a major defense mechanism against infectious diseases. Pacific white shrimp (Litopenaeus vannamei) is one of the most important marine crustacean species with global presence in the aquaculture industry that is at high risk of being contaminated with microplastics due to its feeding habits and benthic food sources. Such contamination may increase the risk of adverse effects on shrimp health. Thus, this study aimed to investigate the effects of oral intake of microplastic in food on the nonspecific immune system gene expression of Pacific white shrimp. We demonstrated immunosuppression at the gene expression level and histological damage of the hepatopancreas in shrimp fed with microplastic-contaminated food, leading to higher mortality. Information from L. vannamei can be used as a model system for other marine decapods. The increased presence of microplastic pollution in the environment and food has the potential to affect shrimp fisheries and aquaculture in the future, as well as further destabilize marine ecosystems already exposed to the combined anthropogenic and climate changes. Abstract Microplastic pollution can interfere with aquatic animal health and nonspecific immunity, increasing the potential for pathogen infection in crustaceans. However, the long-term effects of microplastics on crustacean immunity are less understood, especially regarding their toxicity in Pacific white shrimp (Litopenaeus vannamei). Effects of high-density polyethylene microplastics (HDPE-MPs) in feed on the mortality rate, hepatopancreas, and nonspecific immune system gene expression of Pacific white shrimp are presented. The LC50 at day 28 of HDPE-MP exposure was determined as 3.074% HDPE-MP in feed. A significant upregulation of the superoxide dismutase (SOD) and glutathione peroxidase (GPx) genes was observed in shrimp that were fed with 0.1 and 0.5% of HDPE-MP; then, they were downregulated significantly, except for the SOD gene expression of shrimp fed with 0.1% of HDPE-MP. The lysozyme (LYZ) gene was upregulated significantly in shrimp that were fed with 0.5, 1, and 3% HDPE-MP for 7 days and downregulated significantly in HDPE-receiving groups for at least 14 days. Significant histopathological changes in the hepatopancreas were observed in the treatment groups. The histopathological score of each lesion was correlated with the increase in HDPE-MP concentration. This study shows that the ingestion of HDPE microplastics can alter the expression of nonspecific immune system genes and damage the hepatopancreas in Pacific white shrimp.


LBA7512 Background: This study evaluated whether motesanib (a selective oral inhibitor of VEGFR 1, 2 and 3; PDGFR and Kit) plus C/P improved overall survival (OS) compared with placebo + C/P in patients (pts) with nonsquamous NSCLC and in a subset of pts with adenocarcinoma.

METHODS
Pts had stage IIIB/IV or recurrent nonsquamous NSCLC and no prior systemic therapy for advanced NSCLC. The study initially enrolled all histologies but was amended to exclude pts with squamous NSCLC owing to a high rate of hemoptysis. Pts were randomized 1:1 to receive up to six 3-wk cycles of C (AUC 6 mg/mL·min) and P (200 mg/m2) with either motesanib 125 mg QD (Arm A) or placebo QD (Arm B) orally continuously. The primary endpoint was OS; secondary endpoints included progression-free survival (PFS), adverse events (AEs), objective response rate (ORR) and association between placental growth factor (PLGF) change and OS. OS was evaluated using a stratified Cox model and 2-sided log-rank test (α=0.03 for nonsquamous pts and α=0.02 for adenocarcinoma pts).

RESULTS
1090 pts with nonsquamous NSCLC were randomized (Arm A/B, n=541/549); 890 had adenocarcinoma (n=448/442). 61% were men; median age was 60 years (range 21-87); 83% had stage IV disease. At the time of analysis, 753 pts had died (608 pts with adenocarcinoma). Median follow-up was 10.6 mo. OS was not significantly improved in Arm A compared with Arm B (Table). In Arm A, PLGF analysis did not show an association with OS. The incidence of grade ≥3 AEs in Arms A/B was 73/59%. Grade ≥3 AEs occurring more frequently in Arm A than B included neutropenia (22/15%), diarrhea (9/1%), hypertension (7/1%) and cholecystitis (3/0%). The incidence of grade 5 AEs was 14/9% in Arms A/B.

CONCLUSIONS
In pts with advanced nonsquamous NSCLC, treatment with motesanib + C/P did not significantly improve OS compared with C/P alone. [Table: see text].


Tianyouhuazhan,was a new hybrid rice combination developed by Rice research institute,China Academy of Agricultural Sciences and so on,which showed high,stable yield and rice quality.It was registered and released for commercial production by National Crop Variety Appraisal Committee in 2008.According to many years rape breeding experience of hybird rice Tianyouhuazhan,the high-yielding seed production techniques of Tianyouhuazhan were summarized after cropping of tobacco.


Strain-rate and stress-rate sensitivity of the compressive strength of first-year columnar-grained ice, first-year congealed frazil ice, and columnar-grained ice from an old floe have been investig...


In the context of locally constant skew-products over the shift with circle fiber maps we introduce the notion of measures with periodic repetitive pattern, inspired by \cite{GorIlyKleNal:05} and which includes the non-hyperbolic measures they construct. We prove that these measures have atomic disintegration along the central fibers.


Organ donation has been a taboo subject in Ecuadorian society because there are different mistaken beliefs around the subject. The lack of information has been an impediment for many people to know that through this process they can save and improve the quality of life of many people. The documentary to be made has the objective of informing people about this topic, and encouraging them to accept organ donation. In addition to having few works done in our country about this subject.


This research examines behavioral, motivational, cognitive, and emotional processes at work during a sales encounter. Thorough scrutiny of the factors that play an important role during a sales encounter is important in order to understand the entire sales process and learn more about how to cultivate and keep loyal customers. This research examines the interaction between selling behaviors and consumer motivation in a manner that produces positive cognitive and emotional responses on the part of the consumer. The aim is to provide salespeople with insights on behaviors that are most appropriate in terms of facilitating consumers' goals, and generating positive emotions that ultimately should help build customer loyalty. In two experiments, salesperson behavior is adapted for consumers with different goals in order to generate positive cognitive and emotional responses. The results indicate that there is an interaction between consumer goals and salesperson behavior that leads to specific hypothesized cognitive and emotional outcomes. Implications are that salespeople should move away from formula-based sales approaches and focus on understanding consumer motivation.


Gait is a complex motor task that requires both low level rhythmic pattern generation as well as higher order cerebral control. With aging neurophysiological changes occur that may affect the ability to maintain stable gait. The purpose of this study was to examine the interrelationships between striatal dopaminergic denervation, oscillatory rhythmic foot movements, and gait in healthy older adults.


Space Shuttle launches produce a cloud containing hydrochloric acid (HCl), aluminum oxide (Al203), and other substances. Acidities of less than 0.5 pH have been measured routinely in association with the launch cloud. In an area of about 22 ha regularly exposed to the exhaust cloud during most Shuttle launches, acute vegetation damage has resulted from the first nine Shuttle launches. Changes include loss of sensitive species, loss of plant community structure, reduction in total cover, and replacement of some species by weedy invaders. Community level changes define a retrogressive sequence. One-time impacts to strand and dune vegetation occurred after launches of STS-8 and STS-9. Acute vegetation damage occurred especially to sensitive species. Within six months, however, recovery was nearly complete. Sensitivity of species to the launch cloud was partially predicted by previous laboratory studies. Far-field acidic and dry fallout from the cloud as it rises to stabilization and moves with the prevailing winds causes vegetation spotting. Damage from this deposition is minor; typically at most 1% to 5% of leaf surface area is affected. No plant mortality or community changes have occurred from far-field deposition.


HAN Shao-gong's novels form a spiritual homeland in which his concern for some aspects of modern civilization has been poetically narrated, such as the outlook of time and space, the mode of existence, homomorphological cultural formation and spiritual formation, man-world relation and so on. In the times with modernity as the mainstream, HAN's novels present the readers with a poetic, heterogeneous nursery of soul as well as a personal, folk and frontier spiritual habitat.


An engine having a cylinder head including an exhaust manifold at least partially integrated therein, the exhaust manifold including an inner separating wall fluidly dividing two merged exhaust lines, each merged exhaust line in fluidic communication with a different pair of adjacent cylinders, and an outer separating wall fluidly dividing a first exhaust line in direct fluidic communication with a first cylinder and a second exhaust line in direct communication with a second cylinder, a lateral width of the inner separating wall greater than the outer separating wall, the lateral axis perpendicular to a longitudinal axis traversing centerlines of each cylinder.


I've spent the past two weeks trying to get a better understanding of the agreement[1] signed by the National Archives and Footnote, about which I raised several concerns in my last post[2]. Before making further (possibly unfounded) criticisms I thought it would a good idea to talk to both NARA and Footnote. So I picked up the phone and found several people eager to clarify things. At NARA, Jim Hastings, director of access programs, was particularly helpful in explaining their perspective. (Alas, NARA's public affairs staff seemed to have only the sketchiest sense of key details.) Most helpful—and most eager to rebut my earlier post— were Justin Schroepfer and Peter Drinkwater, the marketing director and product lead at Footnote. Much to their credit, Justin and Peter patiently answered most of my questions about the agreement and the operation of the Footnote website.


By using a gaseous mixture composed of tetraisopropoxytitanium, nitrogen and hydrogen in PACVD process, we obtain Ti(OCN) layers of a good performance properties, such as a high hardness and good resistance to corrosion and to frictional wear. The optimum temperature of the process is 500°C. At higher temperatures, the surface microhardness decreases. When the process is carried out at 700°C, a surface layer which contain titanium cannot be obtained, only a diffusive oxycarbonitrided layer forms. Spectral investigations by optical emission spectroscopy have shown that the active particles that take part in the formation of the Ti(OCN) type layer are titanium ion Ti - , nitrogen particles: N - , N 2 ', NH, oxygen atoms and CN radicals coming from the gaseous atmosphere and also nitrogen from the pre-nitrided substrate.


Peak-to-Valley departure (PV) is a widely used parameter in evaluating the quality of optical surface and wavefront.However,there is great uncertainty in optical surface testing using high resolution interferometer.In order to evaluate the quality of optical surface and wavefront more precisely,PV20,PVr and PVq are discussed.Through numerical simulation and experiment,it is proved that these three parameters can not only represent the real optical surface,but also be insensitive to interferometer spatial resolution.In addition,they have great advantage in metrology repeatability,hence,PV20,PVr and PVq are better than PV for characterizing optical surface.


In this work at 96 patients with irritable bowel syndrome (IBS) by clinical current are investigated psichosomatic of feature and quality of life. Is established, that IBS is accompanied by frustration disturbing depress of character, development social psychological disadaptation and expressed decrease of quality of life of the patients. The comparative study of clinical efficiency of basic therapy with amitriptilin promoted not only faster reduction abdominal pain, dispepsia and metiorism, but also essential improvement of quality of life of the patients.


Attribute reduction is one of the key problems for the knowledge acquisition.Based on the atˉtribute reduction algorithm of discernibility matrix,attribute costs is added in as heuristic knowledge.Thus we put forward a heuristic attribute reduction algorithm based on the relative difference table.The experiment results show that the new methods can obtain the better attribute reductions more effectively and efficiently.


David Basler's commentary identifies five unasked questions in my work, and provides excellent answers to them. His explanation of the gradual evolution of higher-order intentionality via a Bayesian account leads to an explanation of the persistence of our deluded belief in qualia.


This study addressed the under-researched area of the impact that hurricanes have on crime. Specifically, this study examined the relationship between two hurricanes, Hurricane Irene and Hurricane Sandy, and burglary rates in Lawrence Township, New Jersey. Data for this research was obtained from dispatch detail provided by Lawrence Township Police Department for all crimes in the area during the years of 2009-2012. This study focused solely on the crime of burglary (n=423) and the months surrounding each of the storms. Results showed an increase in burglaries after Hurricane Irene and a decrease in burglaries following Hurricane Sandy.


Vitamin C is an important antioxidant. Study conducted revealed that vitamin C can alter certain cellular immune functions and humoral factors both in vivo and in vitro. The aim of this study was to evaluate, through a meta‐analysis of clinical studies, the association between Vitamin C supplementation and leukocyte chemotaxis.


The nucleolus is a well-known single-valued solution to transferable utility cooperative games. It has many desirable properties, but it might fail to satisfy certain types of monotonicity. It can happen (even among 4-player convex games) that an increase in the value of a coalition, while keeping all other coalitional values fixed, results in a strict decrease in the nucleolus payoff to a coalition-member. There are classes of games, however, in which it is typically not possible to change only one of the coalitional values, since they are determined from externally given data. In such games the proper question is whether or not the payoffs at a point-valued solution responds in a monotonic way to changes in the underlying data. Assignment games are models of two-sided matching markets, where only bilateral cooperations can generate added value. Thus, an assignment game is completely determined by the matrix consisting of the profit values of all possible mixed pairs of players. We show that if we increase one entry in the profit matrix but keep all other entries fixed, the nucleolus payoff cannot decrease for either the row or the column player in the corresponding assignment game.


Objective To asses the clinical effect of the leukotriene antagonist receptor(montelukast)combined inhaled glucocorticoid on bronchial asthma.Methods Forty and nine cases of moderate or serious bronchial asthma were divided into control and treatment groups randomly.Both groups were inhaled glucocorticoid.The treatment group were added with montelukast.After 4 weeks with the continuous therapy,the difference of pulmonary function,interleukin-4(IL-4)and interleukin-13(IL-13)were compared.Results The pulmonary function of two groups were improved after treatment.The puhnonary function of treatment group was improved more singnificandy than that of control group.IL-4 and IL-13 of two groups were declined after treatment,treamt group changed more significantly.Conclusion The combined treatment by the oral montelukast and inhaled glucocorticoid on asthma is better than inhaled corticosteroids alone at improving the pulmonary function and airway inflammation of asthma patients.


The synthesis of nanostructured powders and films based on rare-earth ferrite garnet Sm3Fe5O12 was carried out with hydrothermal as well as with the method of precipitation of aqueous solutions of nitrates on the substrate surface. Using atomic force microscopy (AFM), scanning electron microscopy (SEM), Raman spectroscopy (Raman), and X-ray phase analysis (XRD), the topology of the surface and the phase composition of the samples were studied. According to AFM and SEM, particle sizes were evaluated and the structural features of powders and films were analyzed. Raman spectroscopy (RS) and X-ray phase analysis were used to examine the chemical composition and crystal structures of synthesized samples. The possibility of simultaneous investigation of the same sample area with AFM methods and Raman spectroscopy made it possible to obtain data of the chemical composition, the presence of impurities and defects, and the shape of macromolecules. Taking into account the set of obtained results, it is shown that materials based on Sm3Fe5O12, due to their structural features and physics-chemical parameters, can be used as filters for industrial sewage treatment.


This study examines the effect of working capital management on the financial performance of Non-financial companies quoted on the Nigerian Stock Exchange over the period 2014 – 2018 while using a panel research design. This work is unique because it considers a sample of 71 companies drawn from all the 10 non-financial sectors of the NSE. Unlike most extant studies, financial performance was captured by earnings per share as a proxy, while the right-hand side variable being working capital management was denominated by Accounts receivable period, Inventory turnover period, and Accounts payable period. This study also considered the effect of some control variables namely annual capital expenditure, age of firm, GDP,  firm size, growth of the company, and firm leverage on EPS.  Data were retrieved from the Nigerian Stock Exchange 2019 Factbook. The model estimation technique adopted was the Pooled Ordinary Least Squares, fixed effect, and random-effect methods. Results from this study are consistent with the theoretical position that all aspects of working capital management have a significant effect on financial performance. While ITP and ACP were negatively related to EPS, APP was found to have a positive relationship with EPS. The research results also reveal that although all the control variables were found to be significant, only the age of the firm was deemed to be positively related to EPS. Based on the findings, the research recommends that firms should focus their managerial attention on lowering their ITP and ACP while increasing their APP, as results indicate that management of these elements of working capital can translate into liquidity and higher profitability.


Due to their mechanism of action, the new oral anticoagulants are named direct oral anticoagulants (DOACs). Dabigatran is a selective, competitive, direct inhibitor of thrombin (Factor IIa) while rivaroxaban, apixaban and edoxaban act by directly inhibiting the activated Factor X (FXa) in a selective and competitive manner. DOACs have a relatively short half-life and almost immediate anticoagulant activity, and rapidly reach the plasma peak concentration. Therefore, they do not need a phase of overlapping with parenteral anticoagulants. After their withdrawal, their removal is sufficiently rapid, although influenced by renal function. Dabigatran is the only DOACs to be administered as a pro-drug and becomes active after drug metabolization. The route of elimination of dabigatran is primarily renal, whereas FXa inhibitors are mainly eliminated by the biliary-fecal route. The drug interactions of DOACs are mainly limited to drugs that act on P-glycoprotein for dabigatran and on P-glycoprotein and/or cytochrome P3A4 for anti-Xa. DOACs have no interactions with food. Given their linear pharmacodynamics, with a predictable dose/response relationship and anticoagulant effect, DOACs are administered at a fixed dose and do not require routine laboratory monitoring.


A deductive physical theory should in principle be a pure mathematical theory together with an identification of certain quantities/concepts ("observables") in the theory and corresponding observable entities in the real world. This identification – the "interpretation" of the theory – should be unproblematic, both for the theoretician and the experimentalist. A general basis for a deductive physical theory, comprising both classical and quantum physics in a unified way, is proposed. The theory is based on successive confidence estimates on quantum-mechanical wave functions corresponding to space-localizations of particles. This allows a direct and simple way of describing both macroscopic and microscopic phenomena by means of the same basic concepts. Central in the axiomatics of the outlined theory is a concept called equiangular sequences of projection operators. It describes a successive sequence of "collapses of the wave function". The proposed theory gives a basis for a general theory of irreversible processes based directly on quantum mechanics. It gives an alternative definition of entropy and an alternative derivation of entropy increase in irreversible processes.


A cow is, first and foremost, a ruminant animal. Its gastrointestinal tract is designed to digest a significant amount of structural fibers (fiber). Modern technological advances in genetics, breeding, feeding, retention and cows' milking make it possible to obtain more than 10,000 kg of lactation milk from a cow, but this can be achieved only if a significant amount of concentrated fodder with high starch content has been included in the diet of these animals. These fodders are a source of energy for the cow, but the microorganisms of the rumen are also actively use it, forming a large amount of acid, which lowers the pH of the rumen and suppresses (sometimes even kills) the vital activity of the micro biota of the proventriculus. An important condition for the formation of lactic acid in the rumen is the presence of oxygen.
Addition to the cows' diet of live yeast helps to reduce the amount of oxygen in the rumen, which, in turn, inhibits the development of lactic acid bacteria and the synthesis of lactic acid by them. On the other hand, anaerobic environment in the proventriculus actively develops cellulose- lytic microorganisms.
Many studies around the world have been devoted to the use of live yeast in feeding of cows. Most of them have been carried out at cows during the period of thermal stress. Part of the research covers only the period of early lactation. Almost all researchers note an increase in the milk productivity of cows; however, a relatively small number of publications are devoted to the problem of milk quality changes under the actions of these microorganisms.
The purpose of this study was to investigate changes in the chemical composition and milk qualitative indicators of cows, which received in the diet the probiotic preparations of live yeast of different manufacturers.
To study the effects of living yeast preparations in the diet on milk qualitative indicators and productivity of cows, they have conducted a scientific and economic experiment under the conditions of the educational and production center of the Bila Tserkva National Agrarian University. During the experiment, the chemical composition of milk, its density, acidity, bacterial insemination and the number of somatic cells have been investigated.
For conducting of the scientific and economic experiment under the conditions of the farm, 30 cows of Ukrainian black-and-white milk breed were selected, from which with the group method three groups were formed: one control group and two experimental ones. The cows of the control group did not consume probiotic preparations, animals of the 2nd experimental group were fed with LevuSell SC at a dose of 1 g/head/day, and the third experimental group – ActiSaf Sc-47 in the amount of 5 g/head/day. The experiment lasted 305 days.
The quality of milk has great importance, because it is a raw material for the further processing and production of a variety of dairy products, the main consumers of which are children. The current state of the livestock industry forces milk processing enterprises to transport milk over long distances (hundreds of kilometers). That is why the introduction of any feed additives in the diet of cows with a different purpose should not negatively affect the quality of milk.
The use of different preparations of live yeast in cows' feeding has affected the chemical composition of their milk.
At almost unchanged indicators of the content of milk sugar and protein in the milk of cows of all groups, the increase in the content of crude fat in the milk of animals of the 2nd and 3rd experimental groups attracts attention. Obviously, such changes are the result of increasing of the digestibility of fiber (structural carbohydrates) in the rumen due to an increase in the micro biota population and normalization of digestion.
Increasing of the fat concentration in milk of cows of experimental groups resulted in a slight increase in the content of dry matter and milk density.
The acidity of milk is an indicator of freshness and its ability to be stored. According to this criterion, the animals of all groups were equal.
One of the largest problems in the dairy industry is the presence of a significant number of microorganisms in raw milk, which are delivered there due to a variety of violations during milking, storage, transportation of milk, etc. The feeding of live yeast to cows of experimental groups had to influence on the rate of bacterial colonization of milk, but even this slight change has taken place in the direction of improvement. Thus, milk of the cows of the 2nd experimental group according to the indicator of bacterial insemination decreased in comparison with the control analogues by 3.1 %. The advantage of the control animals over the cows of the 3rd experimental group was 4.0 % according to this criterion.
The largest changes in the diet with live yeast of dairy cows were measured by the content of somatic cells in milk. Thus, at cows of the 2nd experimental group, this indicator decreased by 28.9 % in comparison with the control animals. Almost identical, namely 28.7 %, the decrease in this rate was at animals of the 3rd experimental group. It is obvious that the normalization of digestion by the introduction of live yeast in the diet of cows, which in turn has led to the improvement of the health of the animal organism as a whole, and udder in particular. It is worth to note that the reduction of somatic cells number in milk of cows of experimental groups was statistically confirmed (P <0.001).
Consequently, feeding dairy cows with probiotic preparations that are the live yeast of Levucell SC and ActiSaf Sc-47 affects some of the qualitative parameters of milk, such as fat concentration, bacterial insemination and the content of somatic cells. According to these indicators, improvement was observed at cows of experimental groups relatively to control analogues.
Key words: a cow, live yeast, milk, Levucell SC, ActiSaf Sc-47, productivity.


The author considered that the study of syndrome differentiation in type 2 diabetes(T2DM) should be integrating both horizontal study with macrosyndrome differentiation and microsyndrome differentiation and the vertical study with syndrome evolution as the key and integrating of disease and syndrome.That is through stratifying of the complex syndromes or analyzing it paragraph by paragraph,starting research from the single syndrome ele ment,the common and individual characteristics of the syndromes were thoroughly explored.That was helpful for controlling the evolution rule of the syndromes in T2DM and guiding the clinical diagnosis and treatment.


BackgroundLife-threatening facial hemorrhage in Maxillofacial Surgery (MFS) has an approximate incidence of 1% in the trauma patient and in elective surgery. The treatment of acute life-threatening hemorrhage in MFS to prevent hypovolemic shock or airway obstruction forms the basis of emergency care and necessitates the need for further analysis given the multitude of options proposed for treatment. A systematic review of the literature was undertaken to formulate an evidence-based approach to the treatment of life-threatening hemorrhage in MFS. Materials and MethodsA comprehensive search of journal articles was performed using PubMed and Ovid databases. Keywords and phrases used were "life threatening facial hemorrhage," "life threatening facial bleeding," "external carotid artery ligation," and "external carotid artery embolization." Our search yielded 1441 articles. In an attempt to focus on hemorrhage exclusively from traumatic and operative events, articles that cited hematological disorders as the underlying cause of bleeding were excluded from the study. There were 40 articles which met the full inclusion criteria and form the basis of this systematic review. The articles were rated based on the level of evidence. There was 1 Level II, 21 Level III, 12 Level IV, and 6 Level V papers. ResultSeven Level III evidence-based studies noted a high association between midface injuries, particularly Lefort III fractures and massive oronasal hemorrhage. One Level II study, 8 Level III studies, and 3 Level IV studies concluded that the internal maxillary artery was most frequently associated with intractable posttraumatic hemorrhage. One Level II, 16 Level III, 3 Level IV, and 3 Level V articles cited anterior and posterior nasal packing and conservative measures as the first attempt to manage traumatic hemorrhage. Subsequently, 8 Level III studies re-enforced the importance of temporary reduction of facial fractures as an effective means to control massive hemorrhage early in the algorithm. Seven Level III studies, 4 Level IV, and 2 Level V studies documented the importance of ligation of arteries as one of the absolute measures to manage facial hemorrhage, whereas 1 Level II, 14 Level III, 2 Level IV, and 3 Level V studies alluded to embolization as the most reliable technique for control of the hemorrhage. In orthognathic surgery, the internal maxillary artery was most frequently the source of massive hemorrhage according to 2 Level III, 4 Level IV, and 1 Level V studies. Two Level III, 5 Level IV, and 1 Level V study proposed packing as the first attempt to tamponade the hemorrhage. Two Level IV and 1 Level V study cited pseudoaneurysm as a potentially life-threatening vascular complication after elective surgery. ConclusionsManagement of facial hemorrhage should be performed in a sequential and consistent manner to optimize outcome. An evidence-based algorithm for posttraumatic and elective life-threatening hemorrhage in MFS based on this critical review of the literature is presented and discussed.


In this paper, a hardware-oriented fast fractional motion estimation (FME) algorithm for H.264/AVC is proposed. For both 1/2-pixel and 1/4-pixel FME, only 4 points are searched, and thus the required processing unit (PU) number is reduced from 9 to 4. Experiments show that the proposed algorithm can provide very similar image quality as full search, and the average PSRN drop is 0.17dB or bitrate increase is 4.08%. Compared with the full search FME hardware architecture [5], the proposed algorithm can effectively reduce about 32.3% hardware cost and thus is very suitable for low-cost and low-power applications.


Abstract The use of honey as a wound dressing is well established in traditional and modern medicine. There are many reports of its effectiveness in clearing bacterial infections in ulcers and abscesses, which suggest that it may be suitable for the intramammary treatment of mastitis. To evaluate this possibility, the species of bacteria that commonly cause mastitis in dairy cows were tested for their sensitivity to the antibacterial activity of honey. The growth of all seven species tested was completely inhibited by a typical honey (with antibacterial activity attributed to its content of hydrogen peroxide) at a concentration of 10% (v/ v) in the agar plates, and two by 5% honey. Six of the species were completely inhibited by a typical manuka honey (with antibacterial activity attributed to its content of a non‐peroxide component) at a concentration of 5% (v/v). Only one species was inhibited by 10% (v/v) artificial honey (sugars and gluconic acid as in honey). As honey is harmless to tissues and would...


Study on printed digit high-speed recognition image processing system of machine parts used in automated product line is introduced. The system recognize digit by extracting a digital feature in conjunction with scanning and tracing digital pixels. The practice shows the algorithm is fast and precise and robust..


An optical system unit includes a light source to project a light onto a document, a plurality of reflecting mirrors to receive the light reflected from the document and forming a plurality of optical paths, a lens to form an image by focusing the light reflected from the reflecting mirrors at a focusing position thereof, and a reading unit disposed at the focusing position of the lens, wherein at least seven optical paths are formed between the document and the lens by the plurality of reflecting mirrors, and a first reflecting mirror that receives the light from the document along a first optical path is disposed lower than the other reflecting mirrors.


The Proceedings of the 1st European Nonlinear Oscillations Conference contain invited contributions of mathematicians engaged in the development of analytical and numerical methods and of scientists working on vibration problems in mechanics, physics, and other fields.


Objective: To analyze the indications and knowledge of traditional healers on the use of medicinal plants for the treatment of wounds. Methods: Quantitative descriptive study conducted with 32 traditional healers from the municipality of Campina Grande – Paraiba, from November 2012 to March 2013. We used a structured questionnaire with 21 closedand open-ended questions on sociodemographic variables, information on the plant species indicated for the treatment of wounds, acquisition of knowledge on the issue and sale of plants. Data underwent descriptive analysis using absolute and relative frequencies. Results: Of the 40 medicinal plants dealers invited to participate in the study, 32 (75%) agreed to answer the interview; of these, 75% (n=24) were women, 50% (n=16) were 60 years old or older, 25% (n=8) lived in rural areas, and only 18.75% (n=6) grew the herbs they traded. In all, 87.5% (n=28) of the respondents worked for over five years in this sector, with the family transmission across generations as the most common form of knowledge acquisition (87.5%; n=28). In all, 18 plants were cited by the traditional healers, with the purple cashew tree as the most indicated (87.5%; n=28), followed by barbatimao (81.25%; n=26) and quixaba (50%; n=16). Conclusion: The present study leaves question about the level of popular knowledge of traditional healers on the use of medicinal plants for the treatment of wounds unanswered given that it comes from a family source without scientific evidence and imprecise therapeutic indication.


Saturation of the input transducer is a frequently occurring difficulty with minimum-variance controllers and results in the variance being significantly greater than in the unconstrained case. Therefore, it is desirable to decrease the likelihood of saturation. In this letter, this is achieved by deriving a control law which minimises the variance over a time interval.


The extreme natural disasters such as rainstorm have been exerting a great influence on the safe operation of power systems. Landslides caused by rainstorm would cause the tower to tilt. Transmission lines may break off under the influence of unbalanced tension and electro-dynamic force, thus causing the system to power off. In order to improve the reliability of system power supply, the landslide displacement forecasting method based on coupling model is studied in this paper. Firstly, the displacement sequence is decomposed by the variational mode decomposition algorithm to obtain the landslide displacement subsequence. Then the adaptive mutation particle swarm optimization algorithm is combined with the support vector machine to realize the displacement prediction based on the coupled model. The result of this displacement forecasting is used for landslide forecasting and early warning of power system security and informing system operators the dangerous towers to ensure the safe operation of the power system. The case study shows that the model based on the variational mode decomposition and the AMPSO-SVM coupling model is accurate for the forecasting of landslide displacement, provides a theoretical basis for the collapse forecasting of the power system tower and practical basis for the safe operation of the power system.


This study aims to examine the effect on the level of customer satisfaction on service quality consisting of Tangible, Empathy, Reliability, Responsiveness and Assurance at Pekanbaru Three Star Hotels. In this study the intended population is all service users at Furaya Hotel and Ibis Pekanbaru. The number of samples selected from the population studied was used using the Slovin method. The type of data used in this study are qualitative and quantitative data. In collecting data from respondents, the authors used questionnaire and interview methods. The results of the study show that in general the quality of services available at Furaya Hotel Pekanbaru and Ibis Hotel Pekanbaru have been good or satisfying for the hotel customers. Sequentially the best or most satisfying dimensions are Tangible, Responsiveness, Assurance, Empathy and Reliability. From the research that has been done shows that the results of this study are using a superior customer service strategy, where companies try to provide more or best service for customer satisfaction.


Background: Nasal septum deviation (NSD) is a facial midline deviation of the septum's bone or cartilage, nasal promoting nasal obstruction which results in mouth breathing with implications on lip and tongue position, high arched palate, and decreased nasal permeability, and nasal turbinate hypertrophy causes a reduction in the size of the nasal airways leading to concha bullosa (CB), mucociliary obstructions, and maxillary sinusitis. Objectives: To evaluate the degree and types of NSD, presence of CB and laterality, thickness of maxillary sinus mucosa (TMSM) about NSD and relationship of NSD alone and in conjunction with palatal arch depth. Materials and Methods: One hundred eighty cone beam computed tomographic (CBCT) images were procured from CBCT archives by random sampling method. Results: The prevalence of NSD and CB was found to be 43.3% and 42.2%, respectively. In these studies, males and females showed equal distribution and laterality with the most common being type II deviation. CB showed predominant unilateral CB. Conclusions: Comparison was made between all parameters NSD and CB, NSD and TMSM showed a strong relationship, and maxillopalatal parameters and NSD showed relatively higher values.


o C to gain further information of mechanism. The pyridinolyses of eleven R1R2P(=O or S)Cl-type substrates in MeCN (eq 1) are reviewed to obtain systematic information on phosphoryl transfer reaction mechanism. The kinetic results are discussed on the bases of thio effect on reactivity, steric effect of R1 and R2 on reactivity of substrate, electrophilicity of substrate, comparison between anilinolysis and pyridinolysis, and pyridinolysis mechanism. Eleven R1R2P(=O or S)Cl-type substrates are as follows: dimethyl phosphinic chloride (1O); 1h