The algorithms that comprise the Variational Trajectory Optimization Tool Set (VTOTS) package are briefly described. The VTOTS is a software package for solving nonlinear constrained optimal control problems from a wide range of engineering and scientific disciplines. The VTOTS package was specifically designed to minimize the amount of user programming; in fact, for problems that may be expressed in terms of analytical functions, the user needs only to define the problem in terms of symbolic variables. This version of the VTOTS does not support tabular data; thus, problems must be expressed in terms of analytical functions. The VTOTS package consists of two methods for solving nonlinear optimal control problems: a time-domain finite-element algorithm and a multiple shooting algorithm. These two algorithms, under the VTOTS package, may be run independently or jointly. The finite-element algorithm generates approximate solutions, whereas the shooting algorithm provides a more accurate solution to the optimization problem. A user's manual, some examples with results, and a brief description of the individual subroutines are included.


Avian Pathogenic Escherichia coli (APEC) and some enterococci are important zoonotic pathogens associated with poultry and some human illnesses. This study was conducted to evaluate the phenotypic antibiotic resistance and resistance genes during the production cycle of healthy free-range meat chickens and egg layer pullets raised in two different controlled farms in South Australia, in particular to determine at which point in the production cycle birds become colonized with antibiotic resistant bacteria. Antibiotic resistance was investigated in faecal E. coli (206) and enterococcal (252) isolates by agar dilution and polymerase chain reaction. Southern hybridization was carried on plasmids from selected multi-resistant E. coli isolates to determine the location of resistance genes. Our results revealed that birds are colonized with resistant bacteria encoding various resistance genes from a very early age. Resistance to ampicillin and tetracycline (and associated resistance genes) were the most frequently detected resistances in E. coli isolates from egg layer pullets and free-range meat chickens. Phenotypically resistant enterococcal isolates from 3-5 days old chickens carried genetic determinants for resistance to tetracycline, bacitracin and tylosin. Whilst statistical analysis revealed there was no significant differences (p<0.05) with the phenotypic resistance observed in the E. coli and enterococcal isolates from meat chickens and egg layer pullets, a significant difference was observed in resistant E. coli isolates containing blaTEM and tet genes. This study demonstrates that newly hatched chicks are already colonized with resistant bacteria which persist through the production cycle and can potentially contaminate eggs and chicken carcasses. This study also confirms that poultry are a potential source of pathogenic E. coli strains.


Objective To discuss the clinical features of NHL marrow invasion and its' relationship with hematology.Methods Analysis the clinical datum of 95 cases of NHL marrow invasion , make routine bone marrow aspiration and hematology test.Results In those patients with marrow invasion , 4 cases in I phase(4.2%),12 cases in II phase(12.6%),36 cases in Ⅲ phase(37.9%)and 43 cases in Ⅳ phase(47.4%);small lymphocytic、diffuse cleaved cell、lymphoblastic lymphoma are main pathologic types;patients with mediastinal lymphadenectasis、splenomegaly and spleen violations are prone to catch bone marrow involvement;56 cases of anemia in patients with bone marrow involuement(58.9%), 42 patients with thrombocytopenia (44.2%),27 cases with leukopenia (28.4%),49 cases of patients leukocyte increased (51.6%),so,anemia is common;three were 30 cases with three items abnormal(31.6%)and 65 cases with one item abnormal at least (68.4%),the incidence of abnormal peripheral blood in leukocythemia patients were higher than that in patients with bone marrow infiltration,Particularly the patients with increased leukocyte or three items abnormalities were more common in leukemia; Abnormal cells in peripheral blood were observed in 66 cases (69.5%); chemotherapy efficiency reached 65.2% in the patients with bone marrow involuement,the median survival time was 11.5 months.Conclusion Marrow invasion in NHL patients is related to clinical stage, pathological types and sites of involvement , bone marrow check should be done to the newly diagnosed NHL patients conventionally as well as the peripheral blood.


The modern history of British deep-sea fishing begins with the railway expansion of the mid-nineteenth century. Rapid transport and the increasing use of ice as a preservative made it possible for fresh sea fish to enter the diets of the inhabitants of inland towns. Fresh sea fish was regarded as almost a luxury food before the railway age, yet by the third quarter of the nineteenth century, it had become a major protein source for the working classes of the industrial towns, and the fried-fish shop had become a working-class institution. The sea-fishing industry underwent a vast market-induced expansion. The census of 1841 enumerated only 24,000 males as being employed in fishing. By 1881 there were 58,000. If the inland consumer ever gave thought to the fishermen who supplied his table, he probably conjured up a picture of a weather-beaten village fisherman going daily to the fishing grounds to return in the evening to his waiting wife and children, bringing the silver harvest of the sea. While he had been at sea his family had busied themselves baiting lines, making and mending nets, and, in the case of the fish wives, performing their traditional function of selling the catch. Such a picture may have been broadly true of the fishing villages of Scotland, Cornwall, Northumberland or the South coast, but a feature of the second half of the nineteenth century was the creation of a new kind of fisherman who crewed the sailing trawlers of the North Sea. The expansion of the market has coincided with the discovery of the rich beds of the North Sea, and to such an extent did the North Sea trawling ports come to dominate the fishing industry that, by the beginning of the twentieth century, Hull and Grimsby were together receiving as much fish as all the remaining ports of England and Wales put together. Those who toiled on the grey North Sea were known as the "smacksmen", and it is the extreme nature of their occupation which is the subject of this study.


Williamson's Knowledge and its Limitsl is the most important philosophical discussion of knowledge in many years. It sets the agenda for epistemology for the next decade and beyond.


Abstract. A connection between matrix orthogonal polynomials and non-abelian integrable lattices is investigated in this paper. The normalization factors of matrix orthogonal polynomials expressed by quasi-determinant are shown to be solutions of non-abelian Toda lattice in semidiscrete and full-discrete cases. Moreover, with a moment modification method, we demonstrate that the Bäcklund transformation of non-abelian Toda given by Popowicz is equivalent to the non-abelian Volterra lattice, whose solutions could be expressed by quasi-determinants as well.


In order to semantically label visual objects in a large amount of images, we propose a new approach which is fast and accurate. The developed automatic object labeling technique relies on the embedded double matching of local visual descriptors detected in the example and candidate images to semantically tag the candidate image with the label associated to the example image, leading thus to the automatic annotation of the candidate image. Our system has been successfully tested on different standard datasets and is compatible with online applications.


This tray unit includes: a card tray (1) on the surface of the opening and the outer circumferential surface of the mounting tray (1) of the clamp (6). Tray (1) having: a bottom surface (2); rising from an outer circumferential portion of the bottom surface (2) to above the outer peripheral wall (3); a flange portion of the outer peripheral direction on the surface side from the outer peripheral wall (3) is extended (15) . Card holder (6) provided with: a card insertion portion (7), which (3) positioned outside along an outer circumferential wall (3) is provided on the outer peripheral wall of the ratio of the tray (1) and detachably mounted card (5); a guide portion (8), which is provided at an upper portion of the card mounting portion (7), and is formed with a higher (3) toward the tray from the outer peripheral wall of the tray (1) (1) an outer circumferential direction of the inclined surface ( 10).


After joining the WTO,the tour service trade of our country acquires the larger development.It has done a major contribution for the service trade exports.In comparison with other service businesses,it has a good growth,competition ability and development potentials.Based on the competitive advantage theory,the paper has analysed the tour service trade on the open market by the SWOT and put forward some suggestions for the tour service trade in our country.


In Drosophila, an organism much used for dietary studies, comprehending the regulation of feeding and the effect of diet requires accurate measurement of food intake. Although flies are normally housed on agar-based foods, direct estimation of solid feeding has been thought infeasible due to the minute amounts they consume. Moreover, it has been technically challenging to precisely restrict the amount of food flies consume during an experiment. Here, we report a label-free, sensitive, and precise assay, DIETS (Direct Intake Estimation and Tracking of Solid food consumption), that is compatible with videography. In DIETS, food consumed by a group of flies, from a small cup is directly weighed over hours to days. Dietary choice is measured in the assay by weighing food intake from two cups with distinct diets. DIETS enables the quantification of a high-fat diet intake over days. Notably, by limiting food in the cups, we could precisely implement targeted dietary restrictions in flies without diluting nutrients or causing compensatory feeding.


.................................................................................................................................................. 4 Introduction ............................................................................................................................................ 5 Background information ..................................................................................................................... 6 Cordilleran orogenic belt: buildup .................................................................................................. 6 Geodynamic evolution of the Western Interior Basin .................................................................... 8 Stratigraphy & Sedimentology of the Williston Basin: Cretaceous ................................................ 9 Stratigraphy & Sedimentology of the Williston Basin: Paleocene ................................................ 11 Tephrochronology ......................................................................................................................... 13 Methods ................................................................................................................................................ 14 Fieldwork ........................................................................................................................................... 14 Mineral separation ............................................................................................................................ 15 Electron Microprobe Analysis (EMP) ................................................................................................ 18 Data Processing ................................................................................................................................. 20 Results ................................................................................................................................................... 22 Tephra physical properties ............................................................................................................... 22 Tephra stratigraphy........................................................................................................................... 25 Flat Creek Northeast section......................................................................................................... 25 Hauso Flats Southeast section ...................................................................................................... 28 Purgatory Hill Southeast section ................................................................................................... 31 Harker Diagrams ............................................................................................................................... 33 Multidimensional scaling .................................................................................................................. 35 Discussion ............................................................................................................................................. 38 Diagenetic alteration and preservation of the tephra layers ........................................................... 38 Geochemical analysis ........................................................................................................................ 41 Geochemical fingerprinting .......................................................................................................... 41 Tephra correlation: geochemistry ................................................................................................ 42 Distortion of positions by multidimensional scaling ..................................................................... 44 Implications of the geochemical tephra correlations ....................................................................... 48 Provenance analysis .......................................................................................................................... 49 Conclusion ............................................................................................................................................. 52 Recommendations ................................................................................................................................ 52 Acknowledgements ............................................................................................................................... 53 List of Figures ........................................................................................................................................ 53 References ............................................................................................................................................ 56 Appendix ............................................................................................................................................... 61


The recent environmental issues the world has been experiencing recently have increased the awareness of consumers of the necessity of a sustainable consumption pattern to preserve the natural environment. Therefore, green consumption has increased, and companies needed to respond to the rising demand for green products by offering a wider selection of environment-friendly products for green consumers. This article aims to study the purchasing intention of green cosmetics in the case of female student consumers in Hungary. The paper extended the theory of planned behavior by including perceived quality and environmental concern as factors that influence the attitude of consumers towards green cosmetics. This research also takes into consideration the effect of subjective norms on the purchasing intention of green cosmetics. The study employs a quantitative study conducted in Hungary in December 2021 (n = 200). The data was analyzed using PLS-SEM to assess the proposed hypotheses. The results of the study were in line with the literature, with perceived quality and environmental concern having a positive influence over the attitude towards green cosmetics. Attitude and subjective norm also had a significant influence on the purchasing intention of green cosmetics. This research provides new insights into how managers can advance the consumption of green cosmetics, by enhancing the quality of their products and focusing their strategies on answering the concerns of consumers towards the environment.


This paper work evidences characteristics of the management and function structure from the Nutriction and Beverages sector (NB), wich nowadays presents several management flaws, mainly, in the Rio de Janeiro State. The author's proposal is to provide a deep study about quality management in the NB sector, revealing legal conditions, presenting life examples and discussing effective management ways. For that, it was made a bibliographical research, in order to find concluded works refering to the theme quality management and nutriction safety. From that, it was selected news from great circulation newspapers wich presented bad management cases in the NB sector. Nevertheless, the bad qualification of the responsible managers for the companies in the NB sector generates the need to be implantated a safe management with quality.


Since the beginning of the 1980's, in the United States, there have been many licensee event reports (LERs) involving setpoint drift in safety or safety/relief valves. The United States Nuclear Regulatory Commission (NRC) has issued a lot of generic communications on this issue and the industry has made efforts to resolve the issue. However, the NRC staff recently highlighted that over 70 LERs involved instances where safety or safety/relief valves failed to meet the allowed setpoint tolerance from 2001 through August 2006. In the present study, we analyzed the U.S. experience with setpoint drift in safety/relief valves (SRVs) at BWRs, pressurizer safety valves (PSVs), and main steam safety valves (MSSVs) at PWRs by reviewing approximately 90 LERs from 2000 to 2006 and examined the trend focusing on causes and setpoint deviation ranges. This study indicates that for SRVs and MSSVs, disc-seat bonding is a dominant cause of the setpoint drifting high and has a tendency to result in a relatively large deviation of the setpoint. This means that disc-seat bonding might be a safety concern from the view point of overpressure protection. For PSVs, the deviation of setpoints is generally small, although its causes are not specified in many instances.


The invention provides a multi-band communication system comprising extremely high frequencies. The core of the invention is: communicating through multi-band, communicaltion switching between m1-mL frequency band groups and lower f1-fN frequency band groups, using LOS/NLOS identification as a standard to select frequency band, exerting advantages of two bands, avoiding defects thereof, getting well complementation.


Ever since the exposure of the Russian interference in the 2016 U.S. elections for the Donald Trump campaign, there has been much discussion of its causes mixed with deep concerns about the possibility of future meddling of this kind by Russia. There has been far less discussion, however, about the wider phenomena this particular intervention is just one recent example of. This chapter provides an overview of what scholars have found so far about partisan electoral interventions. It first describes the main methods through which foreign powers are known to have tried to intervene in elections in other countries in order to determine their results, as well as the long history of such efforts, going back to the very start of competitive national-level executive elections. The chapter then briefly summarizes the current academic research on the effects of such interference on the target, from its immediate effects on the intervened election results to their medium- and long-term post-election effects on the targets welfare (such as the quality of its democracy). Both parts illustrate that concerns about such foreign interference are indeed quite justified—it is a common, multifaceted phenomenon that can, in many cases, cause serious harm to its unfortunate targets.


This study aims to determine the effect of remuneration on teacher motivation at Al Amin High School, Pamijahan District, Bogor District. The research method used was an inferential type of research with a quantitative approach, with the subjects of the study being teachers of Al-Amin High School and the respondents of this study were all teachers of Al-Amin High School. Sampling was carried out using the method of probabilistic sampling, namely using a saturated sample. Data collection by questionnaire method. The data analyzes used in this study are descriptive respondent analysis, descriptive statistical analysis of variables, hypothesis testing using normality test, homogeneity and hypothesis testing using simple linear regression analysis and t-test.
The results of the study, processed with the computer program SPSS version 16.0 for Windows, showed that the r2 value was 0.477, which means that 47.7% of charismatic leadership affects the work ethic of teachers in the Modern Man Ana Islamic boarding school, and the remaining 52, 3% influence of other factors not included in this study.
The results of hypothesis testing using a simple linear regression analysis show that compensation affects the motivation of teachers at Al-Amin High School, Pamijahan District, Bogor. The results showed that the value of the beta coefficient (β) was 0.812, indicating that the compensation had a positive effect on the motivation of teachers at Al Amin High School, Pamijahan District, Bogor District. The contribution of the compensation effect to the work motivation of teachers is (∆R2) 0.477 or 47.7%; this shows a significant effect, so this study was able to prove the hypothesis. The value of the regression coefficient of 0.812 indicates that with an increase in compensation by 0.812; teacher's work motivation increased by 0.812; tcount of 4.576 > ttable 2.068, so we can conclude that the compensation variable (X) affects the teacher's work motivation (Y) Compensation has a significant impact on teacher motivation. Thus, this study responds to the proposed hypothesis that compensation has a positive and significant effect on the motivation of teachers at Al Amin High School, Pamijahan District, Bogor District.

Key words: remuneration, teacher's work motivation.


The great survivor First impressions, Casablanca In Lyautey's bungalow Kasbahs and imperial cities The oldest inhabitants France deposes Sultan Mohammed Resistance and terrorism Sultan Mohammed returns King Mohammed V Armed rebellions Stirrings down south King Hassan rules L'Etat, c'est moi! Plots and parliament War with Algeria Goodbye to Ben Barka' The sinister Oufkir' The cutthroat at Skhirat Operation Overflow fails Oufkir and the devil's advocate The secret garden Abortive leftist uprising Leftist revolutionaries Corruption The king of the parties The Green March All over, bar the fighting War in Western Sahara Diplomatic demarches Reconciliation with Algeria A religion of tolerance The Defender of the Faith The female majority Press freedom Democracy and human rights The economy King Mohammed VI.


Data sharing and reuse are becoming the norm in quantitative research. At the same time, significant skepticism still accompanies the sharing and reuse of qualitative research data on both ethical and epistemological grounds. Nevertheless, there is growing interest in the reuse of qualitative data, as demonstrated by the range of contributions in this special issue. In this research note, we address epistemological critiques of reusing qualitative data and argue that careful curation of data can enable what we term "epistemologically responsible reuse" of qualitative data. We begin by briefly defining qualitative data and summarizing common epistemological objections to their shareability or usefulness for secondary analysis. We then introduce the concept of curation as enabling epistemologically responsible reuse and a potential way to address such objections. We discuss three recent trends that we believe are enhancing curatorial practices and thus expand the opportunities for responsible reuse: improvements in data management practices among researchers, the development of collaborative curation practices at repositories focused on qualitative data and technological advances that support sharing rich qualitative data. Using three examples of successful reuse of qualitative data, we illustrate the potential of these three trends to further improve the availability of reusable data projects.


This paper introduces a new hybrid topology of multilevel inverter capable of generating 21-level output voltage. The proposed topology is built using the combination of cross-switched bridge and a conventional full H-bridge. Compared to the conventional topologies and other hybrid topologies, the newly introduced multilevel inverter has the ability to maximize the number of voltage levels utilizing lower number of DC voltage sources, integrated bipolar transistor (IGBT) switches and gate drivers. A low frequency modulation technique is used to generate the ideal multilevel output voltage and gate pulses. Furthermore, the proposed topology is validated by building a hardware prototype and obtaining relevant experimental results. The acquired simulated and experimental results indicate the proper functioning of the proposed hybrid topology along with the compatibility of the applied modulation technique. Normal 0 false false false MS X-NONE X-NONE /* Style Definitions */
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In this work we show the results of low frequency noise measurements (LFNMs) in staggered bottom gate top contact organic thin film transistors (OTFTs) made with dinaphtho-[2,3-b:<inline-formula> <tex-math notation="LaTeX">$2^{\prime} $ </tex-math></inline-formula>,<inline-formula> <tex-math notation="LaTeX">$3^{\prime} $ </tex-math></inline-formula>-f]thieno[3,2-b]thiophene (DNTT) as semiconductor layer and CYTOP<inline-formula> <tex-math notation="LaTeX">$^{\text {TM}}$ </tex-math></inline-formula> as dielectric layer. The measured 1/f noise follows a correlated number-mobility fluctuation mechanism with an extracted trap density <inline-formula> <tex-math notation="LaTeX">$ < {10}^{{10}}$ </tex-math></inline-formula>cm<inline-formula> <tex-math notation="LaTeX">$^{{-{2}}}$ </tex-math></inline-formula>eV<inline-formula> <tex-math notation="LaTeX">$^{-{1}}$ </tex-math></inline-formula>, the lower value ever reported for OTFTs and comparable to c-Si devices. On the other hand, the extracted Coulomb scattering parameter is in the order of <inline-formula> <tex-math notation="LaTeX">$10^{{7}}$ </tex-math></inline-formula>Vs/C, in line with previous measurements on organic transistors. In particular we found similar results from device batches with technological differences and a much lower noise from reference devices with SiO2 dielectric, suggesting that the low noise and extracted trap density can be mainly attributed to the quality of the DNTT/Cytop<inline-formula> <tex-math notation="LaTeX">$^{\text {TM}}$ </tex-math></inline-formula> interface.


The behavior of a coated asperity contacting with a rigid flat during the loading and unloading processes is investigated using the finite element method. The power-law hardening elastic–plastic su...


Abstract Endosperms of fenugreek and carob which have been leached following their isolation exhibit increased activity of endo-β-mannanase, part of which is released into the surrounding incubation medium. This activity was suppressed by the addition to the endosperms of abscisic acid or endosperm/seed coat leachate. The leachate from carob inhibited the increase of endo-β-mannanase activity in fenugreek and that from fenugreek inhibited enzyme activity in carob but more weakly; neither of these leachates inhibited the production of α-amylase in wheat endosperm. Polyethylene glycol-induced stress on non-leached endosperms inhibited endo-β-mannanase production, but not when the stress was applied following endosperm leaching. However, the stress did reduce the amount of enzyme released into the surrounding incubation medium. Several isoenzymes of mannanase could be detected on isoelectric focusing activity gels in the endosperms of both fenugreek and carob, but their pis differed between the two species. When activity was suppressed by ABA or leachate, all pl forms declined equally.


An attempt to formulate the general regularities of changes in the content and composition of manganese-iron concretions in soils developed on different parent materials in humid landscapes of the Russian Platform is made. It is established that the intensity of concretion development is controlled by the degree of soil bogging and by the hydrological regime of soils. Independently of rock genesis, the maximum of concretions occurs in slightly gleyed (more rarely, gleyed) soils. The fractional distribution of manganese-iron concretions is not affected by fluctuations in weather conditions over many years. As the degree of soil bogging grows, the fraction of manganese in concretions decreases, while that of iron increases. The maximal accumulation of microelements (e.g., Co, Pb, and Cd) is noted in Mn-enriched concretions. Concretions contain roentgen-amorphous iron and typically have a low magnetic susceptibility. The advantages of quantitative diagnostics of the degree of soil bogging according to the chemical composition of concretions are shown.


This study was carried out to determine the effect of using different levels of white sorghum grain on performance, eggshell quality, egg internal quality and yolk colour parameters in laying quails. For this purpose, 168 female Japanese quails were randomly distributed to 7 treatment groups with 8 replications each containing 3 quails. Treatment diets were created by using white sorghum grain at the level of 0, 5, 10, 20, 30, 40 and 50%. The feed intake of the group using of 5% white sorghum grain in the diet was significantly higher than the groups using of white sorghum at 30, 40, and 50% (P<0.01), but other performance parameters were not affected using white sorghum (P>0.05). Damaged egg rate and eggshell thickness, which are among the eggshell quality parameters, were significantly affected by the treatments (P<0.05), and the damaged egg rate increased significantly at 50% white sorghum grain level. Among the egg internal quality parameters, yolk index significantly increased with the using of white sorghum grain at the levels of 5, 10, and 20% (P<0.01). Yolk colour parameters were affected using white sorghum grains in the diet and compared to the control group (0%), Roche scale score significantly decreased from 40%, a* value 5%, and b* value 20%. The yolk L* value increased significantly with the use of white sorghum grain at the levels of 40 and 50% compared to the control group. According to these results, considering the performance and egg quality of quails, it shows that white sorghum grain can be used up to 30% in quail diets.


In a team‐based organization, the performance not only of the teams as a whole but also of their individual members needs to be managed and managed very well if tall performance (consistently competent, ethical, and motivated behavior that always produces the best results) is to be reached and sustained. In this article, four principles are first overviewed that underlie a new model of performance management designed by the author. The principles are those of tall performance, accountability, responsible empowerment, and performance management. An overview of the new model is then given. Among the model's salient features are the way it preserves the "we" without sacrificing the "me", a non‐traditional way to do performance appraisals, and accountability not only for results but also for behaviors, including ethical conduct.


Major changes in UK bus and rail operation have brought benefits and problems. Short-term demands for high returns have led to the slashing of costs and to great productivity improvements. At the same time there are high levels of investment in new vehicles and upgraded rolling stock. Marketing and human relations issues have been increasingly marginalized in many places. The development of a longer term, market driven, customer focused strategy is therefore an urgent priority.


This paper analyzes the concept, essence, characteristics and types of PE teaching details from the theoretical level, and explores the strategy of using and regulating PE teaching details to promote PE teaching resources formation. It points out that the importance of physical education teaching should be strengthened, the unity of teaching art and wisdom of PE teachers should be promoted, the quality and efficiency of PE teaching should be improved, and the students' physique should be improved.


The Apocalypse, as the last book of the New Testament, is known of its symbolism, where symbolism of numbers plays an important role amongst other categories. The article addresses the symbolism of number ten in that Book. Beginning with the Old Testament, number ten symbolizes certain completeness, and often is part of elements' listing of ten. This fact alone shows its symbolic meaning, indicating fullness, greatness and completeness. The New Testament continues that symbolism. In the Apocalypse, number ten appears 9 times, always in the context of opposition to God and to the Son of God.  It embraces certain negative aspect of completeness, yet it remains limited. Letter to the Church in Smyrna, includes the prophecy of persecution, which as being devil's creation will last ten days (2,10), symbolizing a short and limited trial period, after which there will be victory of those faithful to Christ. Further, in 12,3, a ten horned Dragon / Devil appears, symbolizing his great strength and power, but also remaining limited. Likewise, the Beast emerging from the sea, has ten horns and ten diadems (13,1; 17,3.7; 12[x2].16). Again, it symbolizes Beast's great royal powers (diadems). Further, an angel explains that ten horns represent ten kings (17,12.16). Symbolically speaking, this represents all powers, which throughout history have served the Beast, realizing its goals in opposition to God, Christ, and His followers. Even though, the power of the Beast and its servants seems to be great and limitless, it is in fact limited by the symbolism of number ten, so frequently used in the Beast's description. The Beast gets defeated by the Lamb, having fullness of power, expressed by seven horns (5,6) and being a victorious Rider, with multiple diadems on His head. The powers of the Dragon, the Beast and their followers get defeated and limited by paschal mystery of Jesus Christ.


The present study was undertaken to evaluate the anti-rheumatoidal arthritis effect of the R. verniciflua heartwood extract, its EtOAc fraction, and its primary flavonoids, sulfuretin and fustin. All test samples showed variably significant inhibitory effects on hind paw edema and trypsin inhibitor activity induced by Freund's complete adjuvant reagent (FCA reagent), and on vascular permeability caused by acetic acid. Treatment with 10 mg/kg (i.p.) sulfuretin for seven days inhibited edema formation by 54.2±3.0%. Test samples, especially sulfuretin, shifted the values of biochemical parameters such as serum-cholesterol, serumtriglyceride and serum-total protein toward the normal and restored the numbers of leucocytes and platelets. These results suggest that the heartwood of R. verniciflua reduces immunological injuries caused by FCA reagent provides evidence that suluretin is an active anti-rheumatoid arthritis agent.


The radioactive aerosol content of the surface air in Antarctica has been measured continuously since 1956, first at Little America station and later at the South Pole station. On-site measurements were made daily of the radioactivity due to bomb-produced fission products and to naturally occurring radionuclides of the radon and thoron series. Later, composite samples covering 3-month periods were subjected to radiochemical analysis for such long-lived radionuclides as Sr90, Cs137, Ce144, Pm147, and Pb210. The natural radioactivity was lower in Antarctica than has been observed at any other geographical location, as might be expected from, the small area of exposed land surface in the vicinity. Fission-product concentrations, however, often exceeded those found in the southernmost part of South America and exhibited more well-defined seasonal variations, with maximums in the antarctic summer.


A theoretical and experimental study of the interaction of the SARS-CoV-2 ORF10 protein with sulfosubstituted cobalt(II) and copper(II) phthalocyanines was carried out. The structures of the most probable complexes of metal phthalocyanines with the ORF10 protein were obtained by molecular docking methods. Cobalt(II) tetrasulfophthal ocyanine binds to the protein in the monomeric state, while the interaction ofORF1 0 with copper(II) tetrasulfophthalocyanine causes aggregation of the formed protein complexes, which was shown by the UV-Vis spectroscopy. Thermal denaturation of the ORF10 protein and its complexes with metal phthalocyanines was studied by differential scanning calorimetry. A joint analysis of the spectral and thermochemical data made it possible to propose a description of the mechanism of thermal denaturation ofthe ORF10 protein.


This study examine the factors of job satisfaction and searches wheather job satisfaction has relation to fire official's performance of work. The purpose of this study is suggest management that can promote job satisfaction of fire officials. This is based on the survey from fire officials in Daejeon metropolitian city. For testing hypothesis casual analysis is needed the major methods of this study is used factors analysis, correlations analysis, and multi regression analysis. Following are the major finds. There are statistically significant relations between 5 independent variables (job motivations, organizational management factors, staff management factors, work environment factors, human relations factors) and job satisfaction of fire officials. But, there are no statistically significant relations between demographic variable(gender, age, position, years of serving and job satisfaction).


Spline smoothing is a popular method of nonparametric curve …tting. It is known that, after a reordering of the data, the spline can be obtained from the smoothed estimates of a state space representation of a time series model for irregularly spaced observations. The key parameter is the signalto-noise ratio. When this is zero the underlying model is a polynomial trend plus noise, otherwise it is a high order stochastic trend plus noise. Time-series tests for the presence of stochastic trends in the context of irregularly spaced data are derived and used as tests for the null hypothesis of polynomial speci…cation against a general nonparametric alternative for cross-sectional data. The distribution of the tests depends on the design matrix of the regressors but critical values can be easily obtained by Monte Carlo techniques. Importantly, the test statistic does not depend on any smoothing parameters. The power properties of the linearity test are evaluated for a range of alternative non-linear speci…cations and compared with the properties of other tests of the same hypothesis. As an illustration, we test for linearity of Engel curves.


Gandhiji's doctrine of Swatchh Bharath is based on two important proverbial statements such as: a) a sound mind in a sound body; b) cleanliness is next to Godliness but also lead to diseaselessness.The health of the nation lies in the health of citizens and thus, the imperative need for all citizens to maintain healthy and clean in every walk of life. In the present day, such a standard of life is possible, if one is made free from environmental hazards and all kinds of activities which pose a danger to life.


In ancient China,through law and conventions,the government provided a series of ways or approaches,such as Provoicing grievances,Yammer,Petition,to meet the demands of people when their rights were damaged,protecting various kinds of their legitimate rights from being harmed too much by tyrannical officials.All these law and conventions did not necessarily have the modern concepts and contents of " Rights Relief",however,they own the basic pursuit for serving fair for people.According to such pursuit,the ways of relieving rights which formed in ancient China mainly include appealing progressively in accordance with administrative levels,appealing to a high level directly,appealing to Empire directly or intervened directly by him,and providing privileges.All in all,these ways or approaches are vertical and monorail,basing on the backbone that seeks the protection from the highest in the way of appealing with strong emotion,not horizontal and the separated in powers.


Uninterrupted electricity supply is the precondition of economic development of a country. Bangladesh has huge electrical power deficiency and to minimize this lagging, Government is importing 250 MW electrical power from India. India is itself an electricity deficiency country and has already relationship of trading with two south Asian countries, but the policies of those trading are not beneficial for those respective countries. On the other hand Bangladesh is richer than many other south Asian countries in respect to primary energy reserve. Proper management of this primary energy and electricity sector, to produce and use electricity properly could be a good solution of running electricity scarcity problem of Bangladesh. In some context inter-countries trading is important in south Asia to have a sustainable economic growth when it is beneficial and preserve the right for both countries. Purchasing power from India cannot be a fruitful solution because it will increase our dependency on them. By this trading we may reduce the electricity crisis instantly but could be a cause of long term negative effect on our overall economy. Moreover most of the energy specialists and learned people have negative opinion about this electricity trading. This trading cannot be the good and permanent solution to solve power scarcity problem of this country. Bangladesh should try to be self sufficient in electrical power by proper management and utilization of its own resources instead of spending money for purchasing power from India.


Nehemiah`s Reformation and his leadership are absolutely positive to Korean churches and their congregation. This paper begins with the concern for the final chapter of the book of Nehemiah, which ends up with the separation of foreign wives and their children from the Jewish community. How can this divisive policy be evaluated positively and successfully? With this question, this paper focuses on the two major opponents of Nehemiah, that is, Sanballat and Tobiah. This paper explores the extra-biblical, intertestamental documents to survey the descendants of the Sanballat and the Tobiads in order to garner information what happened to their descendants after the period of Nehemiah. This paper presents through the examination on the Elephantine papyri and the Samaria Papyri that the Sanballat family continued their governorship long after Nehemiah and maintained their Yahwistic religious allegiance up until the end of their fate. Similarly, this paper shows through the Zenon papyri, Josephus, and the archeological site in the present Jordan that the Tobiads were also governors in Ammon just before the emergence of Antiochus IV in Palestine. The post-biblical materials show that both the Sanballat and the Tobiads continued to govern Samaria and Ammon and also continued to have close relationship with Jerusalem long after the period of Nehemiah. This fact tells that Nehemiah`s policy was not successful at all. And this result gives us a hint that his reform was not purely religious in its agenda and motivation. This paper proposes that Nehemiah`s reform reflects political conflicts within the Jewish inner circle to control hegemony over the Palestine area.


As the time of service-based economy has come, service industries have faced competitive challenges that like the mushrooms after rain. Gradually, they take the enhancement of human resource concept seriously. Thus, insurance service industries should take the human resource more seriously which they ignored before. In fact, accumulating the human resource and knowledge is the key point to handle the successful business and to make differences. This study wants to find appropriate mediators influencing the relationship between internal market orientation and customer orientation. We try to explain internal marketing from marketing orientation and employee viewpoint. For one thing, whether employees increase the organizational loyalty because they feel the concept of their company is taking them as customers. Then, they result in higher customer orientation. For another, the internal market orientation of organization influences their customer orientation mainly through the mediating effects of internal service quality. Also, we discuss the relationship within organizational commitment, internal service quality and customer orientation. This study distribute questionnaires to the Life Insurance Company which fit in our research topic. This paper used 322 received questionnaires to analyze it with LISREL. The majority results support our hypotheses. The result show that internal market orientation and customer orientation have positive relationship through internal service quality and organizational commitment.


Supported gold catalysts, e.g., Au on Al2O3, Fe2O3, CeO2, MnO2, TiO2, ZrO2, activated carbon, titanium silicalite TS-1, were prepared and used for the isomerization of linoleic acid (cis-9,cis-12-octadecadienoic acid) to conjugated linoleic acids (CLA) in the presence of hydrogen at 165 °C in a batch reactor. The best results were obtained using a catalyst with 2 wt % Au on TS-1, which exhibits a high selectivity (78 %) towards CLA. The two biologically active target CLA isomers, i.e., cis-9,trans-11-CLA and trans-10,cis-12-CLA, were the main products. During the isomerization of linoleic acid to CLA, consecutive reactions also took place. These were the hydrogenation of linoleic acid and CLA to monounsaturated octadecenoic acids and the further hydrogenation of monounsaturated acids to stearic acid. Thus, gold catalysts are capable of isomerizing linoleic acid to CLA and hydrogenating their double bonds to an extent that depends on the Au catalyst used.


Purpose:This study was performed to compare the therapeutic effects according to duration of medium-dose aspirin(50-60 mg/kg/day) therapy at the acute stage of Kawasaki disease(KD). Methods:Total 87 patients with KD were enrolled in this study. We performed retrospective analysis of clinical characteristics and echocardiographic findings based on medical records. Patient were randomly divided into 2 groups according to the duration of aspirin therapy at the acute stage of KD. Long-term group(LG, n=55) was administered medium-dose aspirin for 2 weeks after diagnosis of KD, and short-term group(SG, n=32) for 48 hours after intravenous immunoglobulin(IVIG) administration. The parameters of therapeutic effects were duration of fever after IVIG administration, incidence of unresponsive patients to single administration of IVIG, and development of transient dilatation or aneurysm of coronary arteries. Results:There was no significant difference in the duration of fever after IVIG between the both group(LG 1.7±1.1 days, SG 1.8±1.1 days; P=0.588). The incidences of unresponsive patient to the single administration of IVIG were 5.5 percent, 6.3 percent in the each group. Transient dilatation of coronary arteries occurred at 18.2 percent(10/55) in the LG, and 15.6 percent(5/32) in the SG(P= 0.761). Prevalence of coronary aneurysm after subacute stage were 7.3 percent(4/55) in the LG, and 9.4 percent(3/32) in the SG(P=0.728). Conclusion:There was no significant difference in the therapeutic effects between long-term(2 weeks) and short-term(48 hours) administration of medium-dose aspirin at the acute stage of KD


The aim of this study was to analyze the influence of intellectual capital, board of commissioners, independent board of commissioner and frequency of commissioners meeting on financial performance. The data used in this study are annual reports In BUMN companies listed on the indonesia stock exchange (idx) in the period 2015-2019. The method of taking data samples using purposive sampling method based on certain criteria. Based on the retrieval method obtained a sample of 21 companies. Hypothesis testing in this study uses multiple linear regression analysis. The results show that frequency of commissioners meeting has no influence on firm value and intellectual capital, board of commissioners and independent board of commissioners have a positive influence on financial performance.


The occurrence of thrombocytopenia in vivax malaria is well documented [1]. However, severe thrombocytopenia is relatively uncommon. We report our experience on the occurrence of severe thrombocytopenia leading to bleeding manifestations in two children. The first case was an 8-year-old girl from the north Indian state of Uttar Pradesh. She was admitted with history of low to moderate grade fever without any chills or rigors for 4 days. There was history of epistaxis 1 day prior to admission. She also had one episode of hematemesis. Parents noticed increasing pallor. There was a mild cough but no history of any other systemic complaints. The child was on Cefixime and Nimesulide twice daily. There was no history of any pre-existing illness or past history of bleeding from any other site. The patient was sick looking at admission. She had tachycardia with hyperdynamic pulses, though there were no signs of heart failure. She was febrile and blood pressure was maintained. Pallor was present. A generalized petechial rash, with ecchymotic spots was present. There was no significant lymphadenopathy. Abdominal examination showed a firm hepatomegaly 3 cm below the costal margin and a firm spleen tip. Initial blood counts revealed hemoglobin of 4.7g%, total leukocyte count of 3400/mm, differential of P34 L58 E5 M3, ESR 110 mm and platelet count of 21 000/mm. In view of the pancytopenia and organomegaly, possibility of hematological malignancy was kept, though infective etiology could not be ruled out and a bone marrow aspiration was performed. The child was started on a broad spectrum of antibiotics and given urgent platelet and packed cell transfusions. The peripheral smear showed a normocytic hypochromic picture. Ring forms of Plasmodium vivax were seen with a parasite density of 1–1.5%. There were no premature or atypical cells. Urine examination, liver function tests and kidney function tests were normal. Malaria antigen was positive for Plasmodium vivax and negative for Plasmodium falciparum. The bone marrow showed normal cellularity. Plasmodium vivax was present. The patient was started on oral chloroquine. She remained afebrile throughout the stay. Spleen initially increased, but then regressed. Blood count after 48 hours had improved to the total count of 5600/ mm and platelet count of 51 000/mm. She was discharged and platelet count after discharge was 165 000/mm.


The effect of purification of Qulu Lake water by magnetic flocculent method was studied. The results showed that the magnetic flocculent method in conbination with ceramsite strainer can make the removal rate of TN and COD to be stabe at 80%, while the purifying test with magnetic ceramsite boat modet can make the removal rate of TN reach to over 90%. In addition, the preparation and the mechanism of magnetic flocculent are elucidated in the paper.


A sensitivity method to estimate the dangerous speed for rotors with multilayer laminated damper was provided.The method,which uses the transfer coefficient method to compute critical speed for every scattered stiffness point in preset stiffness domain,tends to verify the dangerous speed of a rotor through analyzing the sensitivity of critical speed changing with supporting stiffness.The first step is to partition the rotor into many stations,and to compute their physical characteristics.The second step is to set the domain of supporting stiffness and scatter stiffness points inside by dichotomy method,then to circularly compute the critical speed and modes corresponding to every scattered stiffness point until the two neighboring stiffness points with the phenomenon of modes changing extremely are found.The third step is to draw the law curve which shows how the critical speeds change with supporting stiffness and find the sub-domain corresponding to the phenomenon of the critical speed changing extremely.The sub-domain should be consonant with that,which is formed by those two neighboring points found in the former step.Then,if more accurate result is expected,in the sub-domain,repeat the second step until find the satisfying critical speed.It is convenient to modularize this method and helpful to avoid dangerous speed in sensitive support stiffness domain.


The standard determination of the QED coupling on the Z pole is performed using the latest available data for R. The direct application of analytic continuation techniques is found not to improve the accuracy of the value of α(M2 Z). However they help to resolve an ambiguity in the values of R in the energy region √ s ∼ 2 GeV, which, in turn, reduces the uncertainty in α(M2 Z). Moreover, they provide a sensitive determination of the mass of the charm quark. The favoured solution, which uses the inclusive data for R for √ s ∼ 2 GeV, has a pole mass mc = 1.33− 1.40 GeV and α−1(M2 Z) = 128.972± 0.026; whereas if the sum of the exclusive channels is used to determine R in this region, we find α−1(M2 Z) = 128.941 ± 0.029.


This paper discusses the theoretical foundation of QALY and examines the assumptions which underlie these theories. It argues that there are methodological flaws in the construction of QALY and that there are inherent risks in its possible application to psychiatry. It also draws attention to fundamental ethical problems with the concept of QALY as a tool for valuing the quality of life or well-being of persons.


Abstract We show a mathematical relation between the potential of the rotating wave approximation and an estimation of the fluctuation in Mori′s theory of generalized Brownian motion. We use this relation to prove that, when an autocorrelation function R A ( t ), t ∈ R concerning the Bogoliubov scalar product is given for a certain quantum observable A in an equilibrium quantum system in finite volume, we can obtain a Hamiltonian H RWA by making the rotating wave approximation from R A ( t ) such that we reconstruct the autocorrelation function R A ( t ) in the system governed by H RWA .


Application of electrophoresis in space processing is described. Spaceborne experiments in areas such as biological products and FDA approved drugs are discussed. These experiments will be carried on shuttle payloads.


Highways serve nearly 80-90% of the population mobility and flow of goods. Utilization of bottom ash, a waste from coal combustion, in highway construction is one of the alternatives to reduce environmental pollution and support Clean Development Mechanism Program of Kyoto Protocol. The aim of this study is to analyze the characteristics of AC-BC mixture that uses bottom ash as partial substitute of fine aggregate and comparing with a standard mixture. Laboratory tests are performed on two different types of mixtures. The tests show that optimum asphalt content for AC-BCStandard mixture is 5.20% while AC-BCBottom Ash mixture is 5.25%. Bottom ash has higher porosity along with a little break field and has round shape so that the asphalt absorption is bigger than the crushed stone. Bottom ash can be used as an alternative aggregate to increase the value of flow of the AC-BC mixture, thus converting waste to valuable material.


The present invention relates to a method for fabricating a pattern on a biosensor Substrate and a biosensor using the same. The present invention provides a method of fabricating a pattern on a Substrate of a biosensor in which an amine group is formed on a Substrate by using polyethylenimine (PEI), and a site to which a biosubstance is immobilized is masked and irradiated with ultraviolet rays. Such that a pat tern having a desired shape can beformed on the Substrate and a biosensor in which the biosubstance is immobilized on the pattern acquired by using the above-mentioned method.


In the presence of a variety of service providers that offer web services with overlapping or identical functionality, service consumers need a mechanism to distinguish one service from another based on their own subjective quality of service (QoS) preferences. Typical approaches in this field rely on trusted third parties to monitor the behaviour of service providers and endorse their performance based on their delivered services to different users. However, the issue of evaluating the credibility of user reports is one of the essential problems yet to be solved in the e-Business application area. In this paper we propose a two-layered preference-oriented service selection framework that integrates trust and reputation management techniques with an advanced procurement auction model in order to choose the most pertinent service provider that meets a consumer's QoS requirements. We will give a formal description of our approach and validate it with experiments demonstrating that our solution yields high-quality results under various realistic circumstances.


The EAA and ASA Presidents are deeply saddened to inform the andrology community that Prof Lynn R Fraser passed away. At this occasion, our colleagues, R John Aitken and Christopher LR Barratt, retraced Lynn's major scientific achievements together with her fundamental contribution to the promotion of the field of andrology all over the world. It was with great sadness that we learned of the untimely and unexpected death of Lynn Fraser, a pioneer who made major contributions to our current understanding of gamete biology. Her passing marks the end of an era when the foundations of our current understanding in this area were being laid down by a small group of gifted researchers armed with little more than a microscope, a keen intelligence and a powerful ability to observe and interpret biological phenomena. Lynn's career began in the early 1970s when she graduated from The University of Colorado, subsequently taking a PhD and a Ford Foundation post-doctoral fellowship at Yale School of Medicine. In 1972, she moved to London to take up a scientific post for the Medical Research Council's Clinical Research Centre in Harrow, where she remained for five years until 1977 when she became a lecturer at King's College, London. She remained at the University of London for 30 years finally retiring in 2007. During her illustrious career, Lynn published 157 publications which were cited around 4000 times. Here, earliest work was on the cell biology of fertilization in the rabbit during which she examined such fundamental parameters as the requirement for a CO2 enriched atmosphere, the nature of the cortical granule reaction and key aspects of the block to polyspermy. When she arrived in the UK, Lynn was one of a small handful of researchers worldwide, who was well-versed in the dark arts of in vitro fertilization (IVF). She was thus in a unique and powerful position to address the major determinants of IVF success and the normality of offspring generated using this revolutionary new assisted conception procedure.1,2 Questions, indeed, that are no less relevant today. Around this time, Lynn switched her animal model from the rabbit to the mouse and so began a phase of highly productive, insightful research on sperm cell biology with which her name will be forever associated. Using this mouse IVF model, she investigated such fundamental factors as the impact of sperm number,3 gamete genotype,4,5 ovulation, induction regime,6 and maternal age7 on IVF outcomes. As this work progressed, Lynn became more focused on the male side of the fertilization equation, describing the importance of sperm capacitation in defining the fertilizing potential of these cells and elucidating the molecular mechanisms that regulate this process. The importance of cAMP,8 potassium and sodium ions,9,10 decapacitation factors,11 calcium,12 a glycolyzable substrate,13 protein phosphorylation14 and the stimulatory role of adenosine15 were all established at this time. This research was highly influential and internationally recognized, many papers generating over 200 citations and involving the description of techniques, such as the use of chlorotetracycline to monitor sperm capacitation, that are still proving their value today.16 In the late 1990s, Lynn used her knowledge of mouse sperm biology to investigate their human counterparts, providing the field with new insights into the mechanisms underpinning capacitation and acrosomal exocytosis in these cells and introducing the world to FPP (the fertilization promoting peptide), one of a series of important physiological regulators of adenylate cyclase in these cells.17,18 As a fundamental scientist, Lynn's original contributions to the world of gamete biology will stand the test of time. Her work was rigorous, creative and often demonstrated enormous prescience in defining areas of future importance. Lynn was combative, passionate, personable and supportive. Although she was involved in several professional societies, for


Abstract: A robust moral psychology based in Aristotelian-Thomist thought is central to Stanley Hauerwas' theology in a way that it was not for John Howard Yoder. While Hauerwas's doctrine of the church is dependent upon Yoder, Yoder's lack of a moral psychology sits uneasily with the demands of Hauerwas's theology, one of which is a fully-developed account of friendship. Hauerwas follows a pattern evident in Yoder's thought wherein the doctrine of the church as a social polity short-circuits fulsome reflection on personal and affective dimensions of faith. By way of contrast, Sebastian Moore and James Alison have developed understandings of love and imitation that provide the basis for a social and personal account of friendship and, hence, a non-alienating vision of the Christian life. ********** [W]e can become transformed vicariously in the transformation of those whose lives have become intertwined with ours. --David Burrell (1) "I oftentimes feel I learned everything from John." (2) Stanley Hauerwas has little use for attempts to understand his contributions to Christian theology that do not point to the influence that John Howard Yoder exerted on him. Nonviolence, Christology, ecclesiology and eschatology are all areas in which Hauerwas's thought has been deeply shaped by Yoder in ways that he has openly acknowledged on many occasions. More importantly, one might say, Hauerwas owes to Yoder the insight that one cannot speak adequately of Christian nonviolence without a robust eschatology; that such an eschatology depends on an appropriately developed Christology; and that any such Christology will be a function of an ecclesiology centered in practices of discipleship. Yet, there are already many accounts of the theological relationship between Hauerwas and Yoder, and I do not wish in this essay merely to add my voice into the mix. (3) So, I will make only a few prefatory comments on the dependency of Hauerwas to Yoder before moving on to examine a connection between Hauerwas and Yoder that I think deserves deeper analysis than it has yet been given. The subject I have in mind concerns how Yoder and Hauerwas solve issues of personal and existential alienation by treating the unhappiness many people experience as a kind of misdiagnosis that can be solved via a judicious application of ecclesiology. As I read Hauerwas reflecting on (and sometimes simply reflecting) Yoder, it seems to me that his posture fails to acknowledge the depth of people's unhappiness in one of two ways. First, Hauerwas can suggest that if people only had an account of the church like Yoder has, and invested themselves in the practices that constitute such an account, they would discover that they really are happy after all. He does this in his more Aristotelian moments, but the tactic of redefining happiness so that the problem we thought we had is no longer a problem seems questionable to me. Second, and more disturbing, is the sense Hauerwas can give that a robust ecclesiology should direct attention away from the cultivation of healthy subjectivities. Many of the students who have taken Hauerwas's "Introduction to Christian Ethics" course over the past few decades can no doubt attest to feelings of shock at his infamous "I don't give a damn about your subjectivity" lecture. Yet, I have no doubt that many of those same students will attest to a sense that the bluster accompanying Hauerwas's lecture is something of an act: He obviously does care about people's subjectivities, given how he is interested in becoming friends with others. To the extent that Hauerwas claims Yoder as a kind of warrant for this posture, I think he betrays his own best insights about friendship and moral psychology. Am I am basing my reservations about Hauerwas's dependence on Yoder in a kind of misunderstanding? Perhaps. Hauerwas does care about the cultivation of healthy subjectivities; he just does not think that many of us have an inkling about health in this regard given the social deformation we endure in late modern cultures. …


TlyA proteins are related to distinct functions in a diverse spectrum of bacterial pathogens including mycobacterial spp. There are several annotated proteins function as hemolysin or pore forming molecules that play an important role in the virulence of pathogenic organisms. Many studies reported the dual activity of mycobacterial TlyA as 'hemolysin' and 'S-adenosylmethionine dependent rRNA methylase'. To act as a hemolysin, a sequence must have a signal sequence and transmembrane segment which helps the protein to enter the extracellular environment. Interestingly, the mycobacterial tlyA has neither a traditional signal sequences of general/sec/tat pathways nor any transmembrane segments are present. Still it can reach the extracellular milieu with the help of non-classical signal mechanisms. Also, retention of tlyA in cultivable mycobacterial pathogens (such as Mycobacterium tuberculosis and M. marinum) as well as uncultivated mycobacterial pathogens despite their extreme reductive evolution (such as M. leprae, M. lepromatosis and M. uberis) suggests its crucial role in evolutionary biology of pathogenic mycobacteria. Numerous virulence factors have been characterised from the uncultivable mycobacteria but the information of TlyA protein is still limited in terms of molecular and structural characterisation. The genomic insights offered by comparative analysis of TlyA sequences and its conserved domains reveal its pore forming activity which further confirms its role as a virulence protein, particularly in uncultivable mycobacteria. Therefore, this review presents a comparative analysis of mycobacterial TlyA family by sequence homology and alignment to improve our understanding of this unconventional hemolysin and RNA methyltransferase TlyA of uncultivable mycobacteria.


The hydrophobicity and limited bioavailability of both drug Curcumin and TiO2 nanoparticles is destroyed herein this work by coating the anatase TiO2 nanoparticles with biodegradable polymer Chitosan. TiO2 nanocarriers for drug Curcumin had been synthesized by simple wet chemical co precipitation route and the nanoparticles functionalized in biological fluids by capping with Chitosan. The synthesized nanomaterials were characterized by UV-VIS, IR and XRD spectroscopic analysis. The morphology and particle sizes were determined on the basis of XRD. The primary biological activities of functionalized TiO2 loaded with Curcumin were tested on Shiegella bacteria for antibacterial analysis. These functionalized TiO2 nanoparticles exhibited higher antibacterial activities at MIC 1μg/ml. compared to free hydrophobic TiO2 and drug Curcumin and shown particle size of 24 nm. and Spherical Morphology with anatase core. This work resulted in a simple drug delivery system of TiO2 for future applications in delivery of hydrophobic drugs to biological systems for antibacterial and anticancer trials.


The precipitation of oxygen was investigated after rapid thermal annealing pre-treatments for 30 s in the range 1100–1250°C and after flash lamp annealing for 3 ms and 20 ms with different irradiances up to melting of the wafer surface. The difference between thermal processing on the second and on the millisecond scales is based on the temperature profiles generated by the different types of processing. These profiles influence the shrinking of grown-in oxide precipitate nuclei and the generation, diffusion, and annihilation of intrinsic point defects and thus the oxygen precipitation during further processing. Oxygen precipitation can be suppressed by flash anneals or bulk defect zones and defect denuded zones for internal gettering can be created both depending on the flash duration and irradiance.


Regardless of sizes or sectors, all organizations could be vulnerable by frauds, especially small business entities were victimized in the greatest percentage of cases, and also suffered excessively huge losses because of fraud. This study aims to describe frauds and how internal control system could help small businesses prevent frauds and thereby reduce risk of frauds. The case study of company D was employed in this research in order to provide practical matters in relation to fraud and internal control system at this company. How a good internal control system should be applied to a small business will be indicated through the case of company D. The literature chapter is collected from various resources such as books, articles and online sources. The empirical data of the case study is gathered by two research methods: questionnaire which sent to employees working at the company and interview which conducted with three managers of the company. After obtaining adequate theoretical framework and practical data, an in-depth and comprehensive analysis is carried out based on those data. The results reveal that the company D is to some extent having a rather good internal control system, yet needs more improvements, particularly attentions from the company's boards of directors to different departments. Several possible solutions are suggested based on the author's understanding of practical current states at company D. It is believed that this thesis is providing helpful information for the case company as well as others in terms of internal control system to reduce risk of frauds.


Apical dominance is the term used to describe the control of the shoot tip over axillary bud outgrowth (e.g. Cline, 1997). It is best demonstrated via shoot tip removal (decapitation), which leads to apical dominance. Indeed, decapitation has been widely used to study bud outgrowth. In contrast, branching may also occur in the presence of a vigorous shoot tip and be modulated by signals emanating from the root and stem. Whereas the term apical dominance can be used to describe branching phenotypes, this may not be meaningful in cases where shoot branching is not mediated predominantly by the shoot tip. Moreover, different hypotheses of branching control may be due to different experimental systems and techniques rather than divergent mechanisms of control between species. Three hypotheses continue to arise that involve a role for the plant hormone auxin. The classical hypothesis states that auxin acts to regulate shoot branching in conjunction with secondary messengers, such as cytokinin (Sachs and Thimann, 1967; Bangerth, 1994; Li et al., 1995). The auxin transport hypothesis proposes that regulatory control is exerted by auxin movement in the auxin transport stream, as opposed to the actual level of auxin (Morris, 1977; Bangerth, 1989; Li and Bangerth, 1999). The bud transition hypothesis postulates that the bud enters different developmental stages that have varying degrees of sensitivity or responses to long-distance signals, including auxin (Stafstrom and Sussex, 1992; Shimizu-Sato and Mori, 2001; Morris et al., 2005). Here, we address these hypotheses and propose that several components of each can be incorporated into one model of shoot branching. Different shoot-branching hypotheses have arisen from experiments that have varied largely in terms of whether they focus on intact, decapitated, or in vitro systems. Although decapitated and in vitro systems are excellent tools for studying apical dominance, the differences between these and intact systems are substantial, giving good reason to consider that branching control may differ in each case. Under natural conditions, plant species with a poor response to decapitation would be likely to have a selective disadvantage. Therefore, apical dominance, however mediated, may have evolved to ensure that bud outgrowth occurs after decapitation, allowing the plant to complete its life cycle. In contrast, branches of intact plants with vigorous shoot tip growth are generally not essential for the life cycle, but rather serve to enhance vegetative proliferation and/or to generate multiple sites for seed production. Excessive branching may be costly and hence branching, especially in intact plants, is likely to be carefully modulated in response to environmental factors, such as light quality, nitrogen and carbon availability, and growth and development of other plant parts. Consequently, it is reasonable to expect that different regulatory systems may have evolved to control branching after decapitation compared with that in intact plants. It is therefore important to distinguish experimental systems that focus on apical dominance using decapitation and in vitro techniques from those that evaluate branching control using intact plants. A further consideration for decapitation and in vitro studies is that these techniques not only involve the removal of a substantial source of auxin, but also the removal of a major sink for nutrients and energy, in addition to invoking stress and biophysical responses not observed in intact plants. If branching in decapitated or in vitro systems is regulated somewhat differently from branching in intact plants, it is reasonable to expect that studies focused on one or the other will lead to different viewpoints (Napoli et al., 1999). Often, the experimental approach implemented (decapitated, in vitro, or intact) is dictated by the plant species studied. For example, two species that have contributed widely to our current understanding of apical dominance, pea (Pisum sativum) and Arabidopsis (Arabidopsis thaliana), have vastly different phenotypes (Fig. 1). Pea plants have long internodes separating their axillary buds from one another and the shoot tip. This phenotype has allowed for experiments using a wide range of systems, primarily during the vegetative phase. In contrast, research using Arabidopsis has predominantly focused on in vitro studies following floral transition, largely due to constraints imposed by its vegetative 1 This work was supported by an Australian Postgraduate Award (scholarship to E.A.D.) and the Australian Research Council. 2 These authors contributed equally to the paper. * Corresponding author; e-mail firstname.lastname@example.com; fax 61–7– 3365–3550. The author responsible for distribution of materials integral to the findings presented in this article in accordance with the policy described in the Instructions for Authors (www.plantphysiol.org) is: Christine Anne Beveridge (email@example.com). www.plantphysiol.org/cgi/doi/10.1104/pp.106.086868


Data compression allows video signals to be transmitted economically on telephone circuits. Telephone lines transmit television signals to remote traffic-control center. Lines also carry command signals from center to TV camera and compressor at highway site. Video system with television cameras positioned at critical points on highways allows traffic controllers to determine visually, almost immediately, exact cause of traffic-flow disruption; e.g., accidents, breakdowns, or spills, almost immediately. Controllers can then dispatch appropriate emergency services and alert motorists to minimize traffic backups.


The authors report a study of the fueling of the plasma core by recycling in the Tokamak Fusion Test Reactor (TFTR). They have analyzed discharges fueled by deuterium recycled from the limiter and tritium-only neutral beam injection. In these plasmas, the DT neutron rate provides a measure of the deuterium influx into the core plasma. They find a reduced influx with plasmas using lithium pellet conditioning and with plasmas of reduced major (and minor) radius. Modeling with the DEGAS neutrals code shows that the dependence on radius can be related to the penetration of neutrals through the scrape-off layer.


Digital photography is been enhanced in excess in past years, and it makes a leading trend for novel and innovative approach towards the forge images. The work is associated with extracting the tampered image in any form and processing it to obtain the required result. Commonly, in an image, it has some noise. The main aim is to de-noise the tampered image and reveal the original image without losing the image features (edges, corners and other sharp structures) by the restoration process. The de-noising is done by the median filter, the noise is been removed and then the restoration is done by the inverse filter.


Dtiring the first year of life, diffuse corneal clouding is usually caused by infantile glaucoma or infections and inflammatory processes. Although several of the mucopolysaccharidases may also cause corneal clouding, other signs and symptoms predominate. Maumenee* described a congenital, hereditary corneal dystrophy characterized by diffuse corneal edema during the first year of life. His report is the only one which even partially resembles the heredi-


I think that to Lord Kelvin is attributed the saying that the scientific attitude to a thing, if you can't do anything else with it, is to measure it. This is the attitude I propose to adopt towards Time. The situation is to some extent analogous to the situation with regard to electricity. Science is unable to say what electricity is, and so it almost denies the word any entrance into a treatise on the subject. It replaces it by the word charge, which is something that can be measured. It is important to avoid hypostatizing time into a thing-in-itself. Instead of trying to say what time is (e.g. Plato's description of it as "the moving image of eternity") we try to find a way of measuring it.


I study the link between house prices, lending standards, and aggregate over-investment in housing. I develop a model of the housing market where the credit market is affected by asymmetric information. Selection is towards less creditworthy borrowers. Asymmetric information coupled with deadweight costs of default can create endogenous boom-bust cycles in house prices. I show that lending standards are loose and the incentives for less-than-creditworthy borrowers to apply for a loan are particularly strong, first, when future house values are expected to be high, which leads to high leverage of borrowers; and second, when safe interest rates are low, which implies low costs of borrowing. However, there are strong nonlinearities in the relationship between borrowing incentives and economic fundamentals. The results shed light on incentive mechanisms that can help explain the developments in the U.S. housing market in the early 2000s. They also imply that loose monetary policy can have a direct impact on the stability of the housing market through the cost of borrowing and the opportunity cost of housing investment.


In this paper, I will discuss the importance of early intervention with vulnerable families where children and babies may be at risk of neglect and disadvantaged by their social circumstances in accessing appropriate, preventative support services. I will describe the Strengthening Families Program located in the Social Work Department of the Royal Children's Hospital, which provides a model for interdisciplinary and intersectoral (welfare and health) collaboration. The Program offers care management to individual families and is working towards systemic changes in the hospital's response to these families. Finally, I will illustrate aspects of the work of the Royal Children's Hospital Strengthening Families Program with a case study wherein a recent history of domestic violence impacted on the family's capacity to access health and welfare services for both mother and children.


Based on the investigation, this paper analyzes the importance and advantages of the golden ecological triangle of Sichuan, Guizhou and Chongqing,"the aircraft carrier of ecological tourism in China" and puts forward the associative exploration of the ancient salt transportation roads and leisure tourism in the area so as to provide reference for the tourism development in the related areas.


This audio feature shows a journey of the bassist Samer George at different stages of his life. It includes interview with Aya Emam, Samer George's student at the American University in Cairo. She shares her experience with Samer as a teacher.


This study examines the relationships between TMT internal social capital, competitive behavior, and firm performance while considering climate for cooperation with competitors and environmental dy...


This paper introduces the connotations and features of the tacit knowledge,analyzes some factors forming the tacit knowledge,and discusses the measures for sharing and managing the tacit knowledge of university library.


The system of N particles moving on a circle and interacting via a global repulsive cosine interaction is well known to display spatially inhomogeneous structures of extraordinary stability starting from certain low-energy initial conditions. The aim of this paper is to show in a detailed manner how these structures arise and to explain their stability. By a convenient canonical transformation we rewrite the Hamiltonian in such a way that fast and slow variables are singled out and the canonical coordinates of a collective mode are naturally introduced. If, initially, enough energy is put in this mode, its decay can be extremely slow. However, both analytical arguments and numerical simulations suggest that these structures eventually decay to the spatially uniform equilibrium state, although this can happen on impressively long time scales. Finally, we heuristically introduce a one-particle time-dependent Hamiltonian that well reproduces most of the observed phenomenology.


Background: Student-run free clinics provide an opportunity to shape medical student practices with and attitudes towards the medically underserved. Previous literature has shown mixed results on how student attitudes change over the course of medical education. The purpose of this mixed-method study is to determine the effect that participation in a student-run free clinic has on medical student attitudes towards the underserved as compared to attitudes of non-participating students.
Methods: The validated Medical Attitudes Towards the Underserved (MSATU) survey was administered in cross-sectional study to student participants in a student-run free clinic and to non-participating medical students (n = 122). Additionally, first and fourth year participant students were interviewed via semi-structured interviews about results.
Results: There was no statistically significant difference in overall MSATU scores between participant and non-participant medical students using Mann Whitney tests. In sub-score analyses, Mann Whitney tests demonstrated significantly higher scores among participants in the total services score (U = 1344.0, df = 115, p = 0.013) and the expensive procedures services sub-score (U = 1401.0, df = 115, p = 0.019). Interviews revealed that positive attitudes towards the underserved are not specific to student-run free clinic participants. Participants did not describe changes in their attitude from clinic participation, believing all medical students had a baseline positive attitude towards the underserved. They did, however, highlight that witnessing the reality of these patients influenced their perspective and future practice.
Conclusions: There were limited significant differences in MSATU survey scores between participant and non-participant students. Interview results suggest that the survey tool was unable to capture changes in the perspectives of participant medical students or the changes in their projected practices but that, participation in a student-run free clinic had an overall positive effect on understanding of the barriers to care and empathy towards the underserved.


A virus of legumes causing a disease described as "little leaf" has infected with differing degrees of severity some 40 per cent. of pasture legumes in experimental plots in subtropical Queensland. The symptoms are similar to those caused by the "big bud-witches' broom" complex of viruses of which it is probably another strain. Transmission studies have shown that the vector is the leafhopper Orosius argentatus (Evans) which also transmits tomato "big bud", lucerne "witches' broom", potato "purple top wilt", and tobacco "yellow dwar"' diseases. The O. argentatus taken direct from the field in Queensland, and its progeny reared in the laboratory, were efficient vectors of "little leaf" whereas the Canberra strain bred in the laboratory would not transmit 'little leaf' and was not an efficient vector of the other "yellows" viruses. The majority of species and strains tested in the genera Crotalaria, Desmodium, Indigofera, and Stylosanthes are susceptible to "little leaf". Within such genera there are a few resistant species or strains with promising agronomic characters. Lucerne and white clover are relatively resistant to "little leaf". The genera Arachis, Centrosema, Doliehos, Glycine, Lespedeza, Leucaena, Pueraria, Phaseolus, Vigna, and Zornia contain species and strains with marked field resistance. Most of the species and strains considered to be promising pasture legumes possess field resistance to "little leaf".


The project of compact-Energy Recovery Linac(c-ERL) at Photon Factory in KEK is a test facility for the 5 GeV ERL, which is one of the candidates of next generation light source. It consists of injector system, merger section, main SRF section, return arc, long straight section and beam dump. The injector system produces beams with a low-energy of 5 MeV and low-emittance less than 1 mmmrad. It causes the large emittance growth by space charge force in merger section, which consists of two rectangular type dipole magnets and one sector type magnet. Dispersion also causes the displacement of bunch sllice on horizontal plane. The displacement of bunch slice is laid on the kick angle induced by space charge force. Also, each slice has the orientation of the phase ellipse on horizontal phase space. Therefore, the emittance growth due to the displacement of bunch sllice induced by space charge force in the horizontal phase space can be minimized by matching the displacement to the orientation of the phase ellipse at the exit of merger. We present the results of the emittance minimization performed by mathcing of the angle of the phase ellipse by scan of CS (Courant-Snyder) parameter.


The case against drug legalization rests on the empirical premise that drug use would increase in the absence of drug control laws. Everything I know about human nature and the effects of drugs supports this. People use drugs because they are pleasurable, and because they are an effective antidote to anxiety, frustration, and feelings of inadequacy. Were drugs legal, they would be socially destigmatized and they would become easier to acquire, cheaper to purchase, and safer to use. Given the genuine psychological benefits of drug use, we can be sure that it would increase were drugs legalized. The predictable increase in drug use alone, however, does not justify drug laws, nor does it provide a convincing argument against legalization. For one thing, drinking might decrease as a result of increased drug use, which would be a good effect if drinking is more harmful. Even if increased drug use would not have this indirect benefit, drug laws impose substantial burdens. They impose risks of criminal liability on those tempted to deal drugs, especially young men in poor urban neighborhoods; they create incentives for gang membership and gang violence; they cost money in law enforcement; they result in outlaw groups abroad having more money and influence than they otherwise would, with dangerous political consequences; they increase the risk of overdose and other health risks commonly associated with drug use; and, of course, they make an enjoyable recreational activity illegal. Given these burdens, the benefits of keeping drug use down must be substantial in order to justify drug control. What are these benefits? This depends on the drug in question. Here I focus on heroin. (1) The strongest argument against heroin legalization, in my opinion, is its predictable effect on the life prospects of young people in poor communities. A person who is ill-educated, whose skills are not in demand, who does not feel admired or respected by society, who has no clear path to social success or financial security, is likely to feel self-doubt and frustration in large measure. Such feelings can be relieved by heroin. Given the intense pleasure and temporary relief that heroin provides, many of those who try it in any community, rich or poor, are likely to use it again and some are likely to develop a habit. Why would this be bad? Habitual heroin use typically lowers a person's expectations of himself and decreases his concern with what others expect of him; it typically weakens a person's motivation to accomplish things and to meet his responsibilities to others. A general increase in the availability of heroin would therefore increase the risk to children of inadequate parenting, and would make it more likely that young persons disposed to drug abuse will not do what they need to do in order to get a decent education, develop good work habits, develop relationships with mentors, and so on. By "drug abuse" I mean drug use that has negative consequences for the user or others that are sufficiently bad to make this use either imprudent or irresponsible. Poor people are not uniquely susceptible to drug abuse. Life is difficult, especially in adolescence. Heroin brings pleasure and relief. We can therefore predict that adolescents in every economic group would begin using it regularly if it were legalized. Some, perhaps most, would "mature out" of a habit, but drug abuse during crucial stages of a person's mental and emotional development, whether by oneself or one's parents, will typically have lasting consequences that are difficult to correct. The greater availability of heroin might distract some young people from problem drinking, but the impact of heroin abuse on a person's development is arguably more severe because the degree of indifference it produces toward tasks and mentors is arguably greater. If it is, then the impact of legalization on poor communities is especially worrisome because an increase in drug abuse there would further clog already narrow opportunities for achievement and success. …


The flood releasing works of the Fengyichang navigation and generation project mainly consist of 3 sand sluicing gates and 19 flood releasing gates.The dam axis is about 657m long and the river bed overburden is 10~16m thick.The project will be constructed at two stages using a 10a flood control standard for the 1st and 2nd stage diversions.The cofferdam will retain water at dry flow period.Through calculation and 2 diversion model tests,the maximum overflow velocity is 5.6~7.4 m/s at wet period,which is basically the flow to use reinforcing cages and gabions to resist scouring.Therefore,the 2nd stage longitudinal cofferdam will be filled by sand gravels and protected by large blocks and reinforcing cages at different parts based on the cofferdam overflow velocity.


Core loss property of a magnetic material, is defined as dissipation of electrical energy in the form of heat during magnetization by an alternating current. Therefore, efforts are always made to minimise core loss value of magnetic materials. In case of electrical steels, core loss can be reduced by controlling a number of metallurgical factors that include inter alia ferrite grain size. It has been reported that, for a given silicon content, core loss value in the steel initially decreases with the increase in the ferrite grain size. However, after attaining an optimum grain size, core loss value starts increasing with further increase in ferrite grain size. Such type of distinct influence of ferrite grain size on core loss property is due to the fact that the size of magnetic domains present in the steel, is directly linked with the ferrite grain size. Therefore, an increase in ferrite grain size results in corresponding increase in the size of magnetic domains and hence, there is lesser number of domain walls to move during magnetisation, which results in lowering of core loss. However, when magnetic domain size becomes very large, the domain walls have to move faster to cover the same distance during magnetisation which results in enhancing the core loss value of the steel which contains ferrite grains coarser than an optimum grain size. In industrial practice, ferrite grain size of non-oriented electrical steels is increased by adopting suitable hot strip rolling parameters which include low finishing and high coiling temperatures. Further to this, both hot rolled and cold rolled coils are required to be annealed to promote coarsening of ferrite grains. It has, also, been reported that addition of higher amounts of aluminum facilitates coarsening of ferrite grain size, though aluminum is generally considered as an effective ferrite grain refiner. In this context, the present study was taken up to understand the efficacy of aluminum addition on ferrite grain size and on core loss property in non-oriented electrical steel with silicon content around 1.5%. It may be mentioned that aluminum is added to the nonoriented electrical steels to form AlN by combining with the nitrogen available in the liquid steel and consequently, to minimise the detrimental effect of free nitrogen on the magnetic properties of the steel. Also, aluminum addition lowers core loss value by increasing electrical resistivity of the steel and, under specific processing conditions, by developing favorable texture for magnetisation.


The archaeology of Oaxaca is best known from research in the highland valleys of Oaxaca and Nochixtlan inhabited by the Zapotec and Mixtec "Cloud People." Recent research has shown, however, that other regions of Oaxaca such as the Mixteca Baja, the southern Isthmus of Tehuantepec, and the lower Rio Verde valley supported large populations and were important centers of political power at various times. This work has also directed attention toward the role of interregional interaction in sociopolitical change in southern Mexico. In fact, most of the recent archaeological research outside of the Oaxaca and Nochixtlan valleys has been aimed at the problem of interregional interaction. At times this focus on interaction probably resulted in part from the reliance by researchers working in little-known areas on comparisons with data from the highland valleys. But the increasing realization of the effects of interregional interaction on sociopolitical change has intensified theoretical interest in this issue. Furthermore, the ecological variability of Oaxaca with its mountains, highland valleys, and long coastline provides a complementarity in natural resources that stimulates interregional commerce and other forms of interaction in the present and undoubtedly did so in the past.