PERMEABILITY of the soil profile and location of impermeable horizons are important in farm planning for proper application of soil and water conservation practices. Permeability data may be helpful in determining whether or not a field tiling system will work satisfactorily. Under some conditions erosion may be reduced by increasing infiltration and permeability through application of conservation practices.


Members of the Soil Erosion Laboratory at Moscow University propose a technique for predicting the gullying hazard posed by human activities, with particular reference to the so-called Midland region of the USSR, comprising West Siberia, Kazakhstan and Central Asia. A map combining the present extent of gullying and the potential hazard is compiled. It suggests that the hazard is greatest in elevated or dissected portions of the permafrost zone because running water tends to have a thermal impact on the upper layers of frozen ground and reduces its resistance to erosion. The hazard is also serious in wooded steppe and northern steppe because of erodibility of the subsoil and intensive runoff. Potential gullying is less likely in the forest zone and deserts (except if irrigated), and poses the least hazard in the southern steppe and semidesert because of low precipitation and generally level landforms. It is estimated that 50 percent of the Midland region may become subject to medium or strong gullying as ...


Conformal Osserman four-dimensional manifolds are studied with special attention to the construction of new examples showing that the algebraic structure of any such curvature tensor can be realized at the differentiable level. As a consequence one gets examples of anti-self-dual manifolds whose anti-self-dual curvature operator has complex eigenvalues.


The invention relates to a waste recycling device with a denoising function and a use method thereof. The recycling device is used for crushing waste plastics and automatically packaging the crushed plastic powder into buckets. The recycling device comprises a plastic crushing device (2), a plastic powder receiving device (300) and conveying and packaging buckets (41 and 42), wherein the conveying and packaging buckets (41 and 42) are arranged at the two sides of the plastic powder receiving device (300) and are used for loading the plastic powder, so as to package and convey the plastic powder; the plastic crushing device (2) comprises a powder output pipeline (21), and the plastic powder receiving device (300) comprises a first receiving plate (32), a second receiving plate (33) and a receiving plate driving device.


A micro-arc oxidation (MAO) coating coupled with nano-Al2O3 particles was produced on AZ31B Mg alloy by a constant voltage mode in a nano-Al2O3 particles containing Na2SiO3- NaOH aqueous solution assisted with ultrasonic vibration, and then its morphology, phase composi- tion, corrosion- and wear-resistance were investigated by scanning electron microscopy, X-ray dif- fraction, electrochemical method in 3.5%(mass fraction) NaCl solution, and friction and wear tes- ter, respectively. The results show that the coupled nano-Al2O3 particles lead the MAO coating to be thicker and denser with smaller sized pores, and the coatings composed of MgO, MgSiO3, and Al2O3. The AZ31B Mg alloy covered with MAO coating coupled with nano-Al2O3 particles shows a corrosion current density about one order of magnitude lower than the one without nano-Al2O3 par- ticles, and the former MAO coating also shows smaller friction coefficient by applied loads of 5 and 10 N respectively. Therefore, the addition of Al2O3 particles to electrolyte solution can clearly enhance the corrosion- and wear-resistance of the MAO coating. The above effect may be ascribed to the fact that the coupled nano-Al2O3 particles dispersed into the coating pores, and then enables


Emotions can be used by students for diagnostic purposes, and can help them to regulate their learning process successfully. In the context of distance learning, few computer tools have been developed to promote awareness and use of emotions. In the present study, we designed a tool called EMORE-L (EMOtion Report for E-Learning) which is an emotion reporting tool able to collect emotions experienced by learners as well as different types of information related to emotions such as information about the way learners evaluate the situation, and their motivation to share their emotions with others. EMORE-L was used by 16 undergraduate students involved in a distance learning program. The method used was inspired from the Experience Sampling Method: students reported their emotions using EMORE-L for 15 consecutive days, one time a day. We present the results of this study and their implications for the design of emotion reporting tools.


PT Japfa Comfeed Indonesia Tbk is second with 24% market share. In order for Japfa to seize market share in the first position, the management realized the need for competent human resources. By knowing the employee competency gaps in the Livestock Warehouse Department, the company can design a program to improve the quality of human resources for the achievement of better quality objectives. The purpose of this research is to analyze the gap competency, find alternative solutions, and give the recommendation to upgrade competency of the employee. The data collected used Likert Scale, processed test data validation using Product Moment Pearson correlation technique formula and analyze by gap analysis and importance-performance analysis (IPA) matrix. The value of the competency gap is obtained by fulfilling the importance level and capability level. Opinions used are opinions by managers and employees. The highest negative importance gap for core competence is the ability to anticipate, identify and solve the problem, while field competence is mastering the way the computer operate. The highest negative capability gap value for core competence is the ability to reach the target for permanent employees and ability to work with high spirits for outsourced employees, while for field competence is mastering how to operate computer permanent employees and master the system of implementation of the seal of vehicle loading in accordance with work instructions for employees outsourcing.


What really drives business success? Ten, twenty years ago, it would have been somewhat easier to answer this pertinent question. What were seen as central to business success were functional hard core derivatives i.e. operational efficiency, financial discipline and speed to market. Customers, essentially customer experience, were never part of the equation. For those very few organisations that bid to be anything different, the concepts customer experience and customer satisfaction were merely an afterthought. Today the picture is slightly different. Organisations are now applying a contemporary business approach and showing more appreciation for customers. Organisations realise that by creating an environment that is pro—consumer, an environment that achieves and maintains a fair balance between organisational process efficacies and customers' needs, an environment that harnesses employees productivity and encourages fluid communication passage between the organisation and its customers, they will not only connect with their customers on an emotional level, but they will be able to build a sustainable brand asset and a long-lasting profitable relationships with their customers.
It is for this reason that the four customer experience elements namely: process, people, channel approach and branding were selected as premise for this study. This study tries to understand and establish the influence of customer experience elements on customer satisfaction at the Industrial Development Corporation (IDC). An investigation was conducted on customer experience within a process-centred approach at the IDC. The study was steered in two stages. The first stage focused on exploratory research, and the second stage focused on descriptive research. The sample consisted of 276 customers. In-depth interviews were conducted with customers to assist the researcher in developing the statements in the questionnaire. A self-administered questionnaire was designed based on theoretical literature provided within the study and information gathered through the in-depth interviews. Various statistical analysis procedures were used to achieve the objectives of the study, including factor analysis, rotated factor matrix, Cronbach's alpha, multiple regression and comparison analysis.


The compound Su-15049, related to the alkaloid lobinaline, alters electrolyte excretion in renal clearance studies. In the isotonic saline-infused dog maximal natriuresis occurs 45 to 60 minutes after drug administration. Chloride is the principal anion which accompanies sodium. There is no significant effect on potassium excretion. The clearance of inulin, an estimate of glomerular filtration rate, does not change. In other experiments the ability of Su-15049 to modify excretion of potassium was studied under conditions in which urinary excretion of potassium was elevated by infusion of 1) hypertonic saline; 2) potassium chloride; and 3) hydrochlorothiazide. In all cases the drug caused a marked reduction in urinary output of potassium. The decrease occurred within the first 30 minutes of drug infusion. During maximal natriuresis in the ensuing half-hour potassium excretion tended to return to but never exceeded control values. Significant inhibition of potassium transport by Su-15049 also occurred during infusion of hydrochlorothiazide in stop-flow experiments. The data show that the drug inhibits sodium reabsorption and exhibits an antikaliuretic effect in dogs under appropriate experimental conditions.


The random access channel model with retransmission packet mechanism is studied in the emergency wireless broadband access network (EWBAN). The success probability and access time delay packet request for MAC protocol access in EWBAN is analysed. The random access channel model with EWBAN retransmission packet mechanism and the MAC protocol is established using simulation results. Theoretical and engineering application guidance is provided for emergency wireless broadband communications.


Field and laboratory studies on residues and dissipation of imidacloprid in pomegranate fruits were conducted during 2010 at the Pesticide Residue analysis laboratory, Department of Entomology, Mahatma Phule Krishi Vidyapeeth, Rahuri, Ahmednagar, M.S. (India). The studies revealed that residues of imidacloprid persisted up to 3 days and 5 days in arils, 5 days and 7 days in whole fruits and 7 days and 10 days in peel of pomegranate fruits at recommended and higher doses, respectively.


A laboratory-scale study was performed for fostering an eco-friendly approach by substituting synthetic colorant with natural plant extracts as dye source in the presence of hard water (prepared from NaHCO3, MgSO4, CaSO4, and KCl). The dyeing behavior of cotton fabric was analyzed using extract from Eucalyptus globulus and Curcuma longa. Alum and ferrous sulphate were used as mordanting agents to mitigate the hard water effect on dyeing properties. The color strength and fastness properties of dyed cotton were studied. The hard water badly affected the color properties of fabric dyed with natural dyes. Mordant lessened the adverse effects of hard water, but not satisfactorily. The sequestering agent proved to be significant in mitigating the negative effect of hard water on fabric dyeing. Moreover, water hardness also adversely affected the extraction of natural dyes from Eucalyptus globulus and Curcuma longa; however, dye exhaustion was improved by mordant and the sequestering agent. Results revealed that the negative impact of hard water on dyeing properties can be mitigated using a sequestering agent.


Base-isolation technique is a new seismic technique,which was involved in Code for seismic design of buildings in 2001.In this paper,the teaching process of designing a base-isolated building as a graduating project for undergraduate students is introduced sysmatically,including design steps,instruction methods,and some ways to overcome the mistakes easily happened by students.Finally,some new ideas from students are also presented.This paper can provide some demonstrations and references for the teachers who intend to develop this kind of work.


The history of Syriac literature is a subject on which Germany has hitherto been behind Great Britain and France; for, while we have excellent histories by Wright and Duval, earlier German publications on the subject have been of a semi-popular character, and the present work is the first complete scientific history of Syriac literature that has appeared in Germany. As a literary production it is perhaps not equal to its predecessors, but as a bibliographical handbook it far surpasses them, for Dr. Baumstark gives all the MSS. which contain any part of a work as well as the editions, and we are amazed to find it stated in the preface that he only began the work in the summer of 1918. Tor the readers of this journal the translations from Greek, especially of lost works, will be the main interest, and they will, if they search for it, find the most complete information; but unfortunately this is a point on which the book is not well arranged, for there is no clear division or distinction between original works and translations, and in many cases the translations are given not under the author's name but under the translator's. For instance, the voluminous works of Severus of Antioch are almost entirely lost in Greek; but he has no paragraph to himself in this book, and a reader who wishes to know what works of his are extant in Syriac, and where they can be found, must turn to the eleven references under his name in the index, and will eventually find what he wants under Paul of Callinicus, Paul of Edessa, Athanasius of Nisibis, and James of Edessa. Logically this is perhaps defensible, but for purposes of reference it would have been more convenient to place the translations in a separate section under the original authors' names. The book is difficult reading on account of numerous strange abbreviations, which necessitate frequent references to the list at the beginning; but this is done to save printing, and under present conditions the author must not be blamed for it. In spite of these small defects Dr. Baumstark has produced a monument of industrious scholarship which will add to his high reputation, and will be a priceless mine of information for all who are concerned with Syriac literature. E. W. B.


This paper examines the smoke emission and properties of polypropylene and flame retarded polypropylene injection moulded plaques. The prepared samples were irradiated in a Stanton Redcroft NBS type smoke box with an incident radiant energy of 2.5 W/cm2. Nucleating agents were also introduced to increase the particle size of the smoke produced. The conclusions reached from this work on the emission of smoke in a non-flaming mode were that as the flame retardant additive content was increased, the optical density decreased, thus extending the time for escape. The emission of smoke from these polymers subjected to other radiant sources and in a flaming and non-flaming mode is being investigated further.


Introduction: Apical ballooning syndrome, Takotsubo cardiomyopathy, or broken heart syndrome, is a rare but currently well recognized clinical entity. It occurs after severe emotional or physical stress, most often in postmenopausal women, and mimics the symptoms and signs of acute coronary syndrome, in the absence of significant coronary injury. This cardiomyopathy is rapidly and completely reversible. The exact pathophysiological mechanism of the condition remains debated; several hypotheses have been put forward, the most credible of which seems to be a sudden hyperadrenergic reaction related to stress. Objective: To report the case of a patient with clinical features of possible myocardial infarction but diagnosed as Takotsubo cardiomyopathy. Case Report: The patient was a 64-year-old woman with no cardiovascular risk factors other than age and menopause, and no particular pathological history. She was admitted on Day 3 with infarct-like chest pain, which appeared following an episode of emotional stress, associated with NYHA stage III dyspnea. On admission, the patient was pain free. The clinical examination found a conscious patient, hemodynamically and respiratory stable, apyretic. The cardiovascular examination was unremarkable. The ECG was in sinus rhythm, showing a QS aspect in the anterosepto-apical area associated with negative T waves in the inferolateral area. The biological workup showed an inflammatory syndrome, with positive troponin at 650ng/l. The thoracic echocardiography showed an aspect of hypokinetic cardiopathy at the dilated stage with severe LV dysfunction (LVEF at 38%), a thin and flexible mitral valve with restriction of the small mitral valve with moderate mitral insufficiency (SOR at 20 cm2 and RV at 19 ml), a dilated left atrium. Coronary angiography showed angiographically healthy coronary arteries, and an MRI was performed, confirming the diagnosis of Takutsbo cardiomyopathy. Discussion and Conclusion: Takotsubo cardiomyopathy is an increasingly recognized clinical entity, characterized by apical left ventricular dysfunction with chest pain, electrocardiographic changes, minimal biomarker changes, and no coronary lesions. In most cases, an episode of emotional or physical stress precedes the event. Its pathophysiological mechanism remains unknown, but high circulating catecholamines seem to be the triggering factor and the most plausible explanation for this primary acquired cardiomyopathy. It is important to be aware of this diagnosis in patients presenting with ACS because its evolution is most often spontaneously favorable.


To transport high-level talents for the tourism industry is an important standard to measure the quality of tourism management talents in Colleges and universities. Combined with the training objectives of Tourism Management Application-oriented Undergraduate Talents in local colleges and universities, the goal is to serve the needs of economic development. In order to improve the comprehensive quality and industry adaptability, the practical teaching mode of tourism management specialty is put forward.


Though the exact origins of active and adaptive optics are unknown, recent history can be traced by the development of components. Earnest development of active and adaptive optical components began in the early 1970s with two areas of emphasis: (1) compensated imaging and (2) laser beam propagation. Typical for defense driven research and development programs, much of the evolutionary successes and pitfalls will forever remain undisclosed. Recent declassification of adaptive optics technology including laser guide star use has opened the way for exploitation by astronomers and others of the component development. It is the sole purpose of this paper to show those that would be users that the technology is mature.


Aim: To evaluate the microleakage of a simplified etch-and-rinse adhesive bonded to pulp chamber dentin with water-wet bonding (WWB) or ethanol-wet bonding (EWB) with and without proanthocyanidins (PA) application. Materials and Methods: Total 88 non-carious extracted human molar teeth were sectioned horizontally to expose the pulp chambers 1.5 mm coronal to the cemento-enamel junction. After the pulp tissue extirpation, canal orifices were enlarged and the root ends were sealed. The samples were randomly divided equally into following four groups according to the four bonding techniques performed using Adper Single Bond 2 [SB] adhesive (1) WWB; (2) EWB; (3) WWB and PA application [WWB + PA]; (4) EWB and PA application [EWB + PA]. Composite resin restorations were performed in all the pulp chambers. Total 20 samples from each group were subjected to microleakage evaluation, and two samples per group were assessed under scanning electron microscope for interfacial micromorphology. Results: The least microleakage score was observed in group 2 (EWB) with similar results seen in group 4 (EWB + PA) (P = 0.918). Group 2 (EWB) showed significantly less microleakage than group 1 (WWB; P = 0.002) and group 3 (WWB + PA; P = 0.009). Group 4 (EWB + PA) also depicted significantly reduced microleakage as compared with group 1 (WWB; P = 0.001) and group 3 (WWB + PA; P = 0.003). Conclusion: The use of EWB technique in a clinically relevant simplified dehydration protocol significantly reduced microleakage in simplified etch-and-rinse adhesive, Adper Single Bond 2, bonded to pulp chamber dentin. Application of PA had no significant effect on the microleakage of the adhesive bonded with either WWB or EWB.


This paper studies the growth and determinants of information technology (IT) trade in the Asia-Pacific region. We argue that the rise of IT trade must be understood within the context of increasing vertical fragmentation of production processes that has occurred in the last two decades. This has implications for the appropriate specification of empirical trade equations for IT products. We present results of pooled bilateral export equations for East-Asian IT exports where foreign direct investment plays a significant role in exports. JEL classification: C33, F14, F23


This article explores the decade-long process by which village-level water committees established a reserve in 2002 to protect communal mountain springs in the Montaña Camapara region of Honduras. In so doing, it considers the conditions under which shared dependence on water resources may motivate cooperation and foster equitable access to water in the face of difficult challenges posed by conflicts over land and water rights claims and degradation of the resource.


Teacher preparation is dependent on a clinical model of instruction where students apprentice with licensed teachers to gain experience in a classroom. It is not always easy to create these opportunities in schools that are local to the university, especially with a large middle-level program. This qualitative study examines how using lesson study in an early clinical experience can create high-quality experiences and develop innovative thinking around lesson design. This research answers the following questions: (1) What events do the preservice teachers identify as memorable in their interactions with students, peers, and teachers during a clinical experience that uses the lesson study model? (2) How does the lesson study model influence preservice teachers' thinking about teaching? The results from the study suggest that a lesson study model is a viable option for middle-level teacher preparation programs. While it solves some practical issues, such as a lack of quality clinical experiences, it also creates an experience where students feel supported, scaffolded, and engaged.


Since Charles Blackley first described the association of nasal symptoms of sneezing, rhinorrhoea, and obstruction with seasonal changes in the pollen count' our understanding of the pathophysiology ofhay fever, seasonal allergic rhinitis, or pollenosis has steadily increased. Pollenosis is one of the best clinical examples of the type I or immediate hypersensitivity reaction. Soluble allergens derived from the pollen grains of trees, shrubs, grasses, and flowers can stimulate both the systemic and mucosal synthesis of specific reaginic antibodies.2 Inimunoglobulin E binds (through the C4 domain of its H chains) with high affinity to Fc receptors on the surface of mast cells and basophils. The mast cells are activated to secrete mediators by a mechanism that depends on cross linkage of the bound IgE antibodies by specific allergens.4 Thus experimental nasal provocation with appropriate allergens induces gross degranulation of mast cells both on the mucosal surface and in the submucosa.5 Nasal challenge causes the release of a whole range of chemical mediators, and these may readily account for many of the symptoms of pollenosis. The activation ofmast cells by IgE leads to the release of preformed mediators including histamine, exoglycosidases, the neutral protease tryptase, and eosinophil and neutrophil chemotactic factors; it also stimulates the generation and release of newly formed mediators, including prostaglandin D2 and the 5lipoxygenase products leucotrienes C4 and D4 that together were previously recognised as slow reacting substance of anaphylaxis.6 Histamine causes both direct and reflex dilatation of postcapillary venules, leading to nasal obstruction; stimulates irritant receptors causing sneezing; and stimulates secretion from goblet cells and submucosal glands.7 Exoglycosidases such as 13 glucuronidase, 13 hexosaminidase, 13 galactosidase, and arylsulphatase together with neutral proteases disrupt the integrity of the mucous membrane through their specific actions on tissue ground substance. Prostaglandin D2 is a potent vasodilator, causing vascular engorgement of the mucosa, while leucotriene C4 increases capillary permeability, causing exudation.8 The interaction of these mediators might be expected to cause oedema of the mucous membrane and nasal obstruction. Chemotactic recruitment of secondary effector cells such as eosinophils, neutrophils, and basophils to the sites ofmast cell degranulation, together with their activation, releases further mediators to compound the inflammatory response which leads to a state of chronic nasal hyperreactivity.7


Ground water with a high concentration of magnesium ion is known to cause deterioration to portland cement concretes. A proposed mechanism for this deterioration process published previously involves an approximate 1:1 replacement of Ca ions by Mg ions in the crystalline phases of hydrated cement. The current study was undertaken to determine which ions, among magnesium, chloride, and sulfate, cause deterioration; whether their deleterious action is individual or interdependent; and to relate this mechanism of deterioration to the outlook for a 100-yr service life of concretes used in mass placements at the Waste Isolation Pilot Plant. Loss of Ca ion by cement pastes was found to be strongly related to the concentration of Mg ion in simulated ground-water solutions in which the paste samples were aged. This was true of both salt- containing and conventional cement pastes. No other ion in the solutions exerted a strong effect on Ca loss. Ca ion left first from calcium hydroxide in the pastes, depleting all calcium hydroxide by 60 days. Some calcium silicate hydrate remained even after 90 days in the solutions with the highest concentration of Mg ion, while the paste samples deteriorated noticeably. The results indicated a mechanism that involves dissolutionmore » of Ca phases and transport of Ca ions to the surface of the sample, followed by formation of Mg-bearing phases at this reaction surface rather than directly by substitution within the microstructure of hydrated cement. Given that calcium hydroxide and calcium silicate hydrate are the principal strength-giving phases of hydrated cement, this mechanism indicates the likelihood of significant loss of integrity of a concrete exposed to Mg-bearing ground water at the WIPP. The rate of deterioration ultimately will depend on Mg-ion concentration, the microstructure materials of the concrete exposed to that groundwater, and the availability of brine.« less


This paper presents results of a qualitative study describing classroom participation in pre-college mathematics classes taught by seven successful community college faculty members. The analysis reveals high levels of student participation coupled with low complexity, which can result in detrimental opportunities for students to learn mathematics. The multiple and competing functions and the diversity of the community college setting makes delivering high quality mathematical instruction more difficult. This paper discusses implications for further research and for practice.


The first counting of mental disorders in Denmark goes back to the 19th century, but the modern era of psychiatric epidemiology was founded in the 1930s and 1940s with population surveys by Stromgren and Fremming. The second era began in 1969 with Dupont's establishment of the nationwide Danish Psychiatric Case Register in the Department of Psychiatric Demography. Since then, a great number of studies of the epidemiology of mental disorders has been performed, mainly concerning inpatient care. Major findings show that treated inpatient prevalence has decreased in parallel with the reduction in number of beds, by approximately 50% to the present number of about 90 per 100,000 inhabitants 15 years and above. Standard mortality rates for suicide among functional psychoses has doubled over 20 years, and first admission rates among psychotics have been almost halved. An exception is seen among eating disorders and borderline states, which show increasing first admission rates. Catchment area surveys show total...


Maternal obesity has been hypothesized to lead to developmental programming of excessive weight and adiposity in offspring. In addition, excessive gestational weight gain (GWG) is also a demonstrated determinant of later‐life adiposity. We examined genome‐wide DNA methylation (Infinium® HumanMethylation450K BeadChip) in umbilical cords (UC) from lean (Ln, BMI<25) and overweight/obese women (OB, BMI蠅25) who gained weight within Institute of Medicine guidelines to specifically identify the epigenetic influence of maternal obesity. Offspring birth weight and infant adiposity at 2‐wk did not differ between groups. Multivariable linear regression analysis of CpG methylation against maternal fat mass at 12 wk while controlling for maternal age, mode of delivery, infant birth‐weight and sex identified 1,269 CpG sites whose methylation status was associated with maternal adiposity (p<0.05). Of these, 54% sites were located in 5'‐UTR and proximal promoter (‐1500 bp) regions. Gene ontology analysis identified processes related to fat cell differentiation to be hypomethylated and processes related to RNA stability to be hypermethylated in OB compared to Ln UCs. Our data suggest that maternal adiposity in the absence of excessive GWG is associated with epigenetic modifications of fetal tissue that may contribute to the development of obesity in offspring. Funding USDA ARS‐CRIS 6251‐51000‐007‐04S.


We consider two ionization-detected stimulated Raman spectroscopic techniques that are suitable for studying the ground-state spectroscopy of species in molecular beams: ionization-gain stimulated Raman spectroscopy (IGSRS) and ionization-loss stimulated Raman spectroscopy (ILSRS). The merits of IGSRS and ILSRS in such studies are discussed in relation to each other and in relation to stimulated-emission spectroscopy. In addition, some advantages of the Fourier-transform implementations of IGSRS and ILSRS are considered. Experimental results on numerous species are presented that show that IGSRS and ILSRS have ample sensitivity and species specificity for the study of weakly bound complexes.


Localized adaptation strategy with cooperation of sleeping mechanism and lightpath bypass reconfiguration is proposed for energy-saving transport in dynamic IP-over-WDM networks. Analysis and Simulations indicate that total energy consumption is reduced by the novel strategy.


When Mogor dell'Amore returns from the Mundus Novus of the Americas to the court of the Mughal Emperor Akbar in Salman Rushdie's The Enchantress of Florence, he brings with him fabulous tales of the "erratic nature of time in that half-uncharted territory." Time, he says, was completely out of control" (328). Not only does it speed up, slow down, and run at different speeds for different people," but there are periods "when it did not move at all" (328). "The locals," dell'Amore relates, "confirmed that theirs was a world without change, a place of stasis, outside time" (328; emphasis in original). The Emperor Akbar, hearing of these contraventions of the laws of time, assumes that it must be a fundamental oddity of the West, in contrast to the prosaic and predictable behaviour of temporality in the East. "[The lands of the West," he thinks, "were exotic and surreal to a degree incomprehensible to the humdrum people of the East," where people "worked hard, lived well or badly, died noble or ignoble deaths, believed in faiths that engendered great art, great poetry, great music, some consolation, and much confusion. Normal human lives, in sum" (329). In this exchange between the Eastern emperor and his emissary to the exotic West, Rushdie whimsically reverses age-old Orientalist depictions of the "timeless time of the East," which relegated the Orient to a static zone of temporal otherness outside of the linear progression of history. The "imaginative, quasi-fictional quality" of Orientalist descriptions of the time and history of the East, as Edward Said writes, dramatized the distance and difference between familiar and unfamiliar spaces (55). While reaffirming the normalcy of the laws of time at home, these Orientalist depictions of exotic temporality also invited Western intervention into lands locked in mythical stasis. The job of the colonizer involved, in part, introducing time to places formerly untouched by it or erratically resistant to it. Rushdie, again reversing the polarities of Orientalism such that the East becomes the site of a "humdrum" ordinary temporality and the West the place of temporal irregularity and instability, mimics the Orientalist view that time control and regulation were purely an imported product of the colonizer. "It was possible, and there were philosophers who argued the point vociferously," he writes, "that time had been brought to Mundus Novus by the European voyagers and settlers, along with various diseases. That was why it didn't work properly. It had not yet adapted to the new situation" (329). Emphasizing the utter normalcy of the laws of time in the exotic Mughal Empire and satirizing Orientalist misrepresentations of foreign time as no less fanciful than descriptions of "flying monkeys," Rushdie highlights the absurdity and arrogance of believing that a fundamentally shared human phenomenon--the experience and regulation of temporal rhythms--could be the special province of only one half of the world, relegating the other half to a zone of temporal oddity, incongruity, and instability. Rushdie's satire of Orientalist treatments of time in this later novel offers a healthy corrective to the critical treatment accorded to time in his earlier "clock-ridden" novel, Midnight's Children. Time, in that novel, has consistently been interpreted in the very Orientalist terms that Rushdie is satirizing in The Enchantress of Florence. According to this reading, Rushdie, resisting the importation of the time of the West, offers instead a mythical, static, and timeless version of temporality, uniquely personal and culturally distinct from the telos-driven linearity of a Western time regulated by clock and calendar. For M. Madhusudhana Rao, the single unified concept of time in both Midnight's Children and Shame is "timelessness" (135), which aids in the protagonists' self-realization as they unchain themselves from a "world of history" that has been "spoiled by deception and horror" (139). …


The large (peak to average power ratio (PAPR)) phenomenon is a downside in filtered multiplexing of the orthogonal frequency division (F-OFDM- Beyond 5G candidate) because of the nonlinearity design of the transmitter. Recently, several hybrid approaches have been implemented to minimize the high value of PAPR, at the expense of increasing the level of computational complexity in the system. In this paper, a new hybrid approach has been introduced throughout parallel to combine the approach of selective mapping (SLM) with the approach of partial transmit sequence (PTS) with (CSS) to improve the efficiency of PAPR reduction with lower complexity in numerical methods. The results indicate that the F-OFDM systems with the proposed hybrid method have superior performance compared to existing hybrid methods in terms of PAPR reduction, side-information, and computational complexity. Furthermore, a new hybrid approach suggested preserving the BER and PSD efficiency without deterioration.


Objective To discuss the methods and the potency for transurethral cryotherapy of the prostate for the treatment of advanced prostatic cancer. Methods 11 cases of advanced prostatic cancer were treated by a combination of transurethral cryotherapy of the prostate, orchiectomy and flutamide from 1990 to 1999. Results The patients were followed up for 3~24 months. The obstruction of bladder outlet and bone pain were relieved with different extent. PSA decreases and the life quality was improved apparently. None of the 11 patients developed recurrence. Conclusion The transurethral cryotherapy of the prostate might be good for the treatment of obstruction of bladder outlet caused by advanced protatic cancer. A combination of transurethral cryotherapy of the prostate, orchiectomy and flutamide was safe, less complication and evident efficacy.


Abstract Reproductive organs of Azolla species (Salviniaceae) from the Lower and Middle Pleistocene of the Dansk Nordso A-1 and A-2 boreholes, central North Sea area, were studied by means of scanning electron microscopy. A new species, Azolla danica, based on massulae is proposed. The megaspore apparatuses of Azolla filiculoides Lam. and Azolla tegeliensis Florschutz are described and the possible affinity of A. danica to A. tegeliensis is discussed. It is concluded, that the A. danica massulae can be regarded as the previously unknown massulae of A. tegeliensis. A tentative, chronostratigraphical subdivision of the Quaternary section is given. The record of A. tegeliensis is the first proof of the presence of limnic deposits of the Tiglian interglacial within Danish territory.


The paper presents a method for electrical load control using an optimization procedure to determine the optimal energy consumption with the utilization of different types of loads depending on their control opportunities, batteries, and renewable energy sources. The method gives flexibility to the energy system in the smart building.


ABSTRACT Transparent triacetylcellulose membranes with immobilized pH indicator (neutral red) as well as with simultaneously immobilized urease and neutral red were used as optical sensors for determination of urea concentrations. Decomposition of urea with the enzyme urease is accompanied by evolution of ammonia. This changes the neutral red absorption, which is proportional to the substrate (urea) within certain concentration limits. As a result of the investigation, standard curve were plotted for determination of urea over the range of 1 to 500 mM using immobilized indicator and free urease. Simultaneous immobilization of indicator and urease permitted determination of urea in the interval 50 to 500 mM. The membrane used contained 0.169 U urease activity on an area of 1.7 cm2. The standard curves were in both cases plotted for 5min treatment of the substrate using the linear region of the kinetic curves for the corresponding substrate concentrations. A possible scheme of the interaction between the activated triacetylcellulose membrane and the indicator is proposed. The membranes obtained are suitable for repeated clinical and ecological applications where urea is to be determined.


In this paper, we studied the hypothesis testing problem for the average life of exponential distribution based on the type Ⅰcensored samples, the test statistics were obtained through improvements in the total test time. We also gave some tables of critical values for this hypothesis test.


We describe the balayage order defined by an analytic gambling house on a Borel subset of a Polish space in terms of our construction of the saturation of the gambling house.


Abstract : A summary of the important aspects of the environment in cislunar space important to the simulation of space vehicles is presented. Models of this environment are developed, and estimates of the required parameters are made on the basis of currently available data. Thes models have been constructed with an emphasis toward maximum simplicity of representation, in order that the computations be compatible with real time simulation of space vehicles. (Author)


On a complex n-manifold with holomorphic projective connexion, any point has a neighbourhood U of which the space of geodesies has naturally the structure of a (Hausdorff) complex (2n-2)-manifold; it is shown that the complex structure of this auxiliary space encodes, in a sense, the original projective connexion by means of a complete analytic family of and#x2119; n-1 's. Rather strikingly, small deformations of the space of geodesies correspond precisely to small deformations of the projective connexion of the primary space. Similar results are obtained concerning the space of null geodesies of a complex n-fold, n ≥ 4, with conformal connexion , a geometrical structure amounting to a holomorphic conformal structure plus a torsion tensor. For n=3 the analysis is complicated by the fact that the analytic family of submanifolds (quadrics; in this case and#x2119; 1 's) representing the points of the primary space fails to be complete; but it can be completed to give a 4- dimensional family, effecting a unique embedding of the original 3-fold in a 4-fold with conformal structure, of which the conformal curvature is selfdual, in such a way that the induced conformal structure is the original one and such that the conformal torsion is related to the second conformal fundamental form of the hypersurface in a canonical linear fashion. In any case, the small deformations of the complex structure of the space of null geodesies correspond precisely to the small deformations of the conformal connexion. It is shown that a space of torsion-free null geodesies admits a holomorphic contact structure, and that conversely, for n ≥ 4, the admission of a contact structure forces the conformal torsion to vanish; for n=3, the contact form constructs automatically a unique metric on the ambient 4-fold in the previously constructed self-dual conformal class which solves Einstein's equations with cosmological constant 1 and blov/s up on the 3-fold, which is a general umbilic hypersurface. These results are in turn used to show that a real-analytic 3-fold with real-analytic positive definite conformal structure and a real-analytic symmetric form of conformal weight 1 can be embedded (in a locally unique fashion) in a real-analytic 4-fold with positive-definite conformal structure for which the conformal curvature is self-dual in such a way as to realize the given structures as the first and second conformal fundamental forms of the hypersurface; and it is shown that a real analytic 3-fold with positivedefinite conformal bounds a locally unique positive-definite solution of Einstein's equations with cosmological constant -1 as its umbilic conformal infinity. By contrast, these results fail when "real-analytic" is replaced by "smooth".


An ozone (O3) analyzer for use in eddy‐correlation measurements is described which has an unfiltered bandwidth of at least 20 Hz and sensitivity of at least 0.1 ppbv at 12‐Hz bandwidth. Based on chemiluminescence with nitric oxide, it is designed primarily for use on meteorological aircraft, but it also works well for tower measurements. It is significant that the detecting mechanism responds linearly to time‐dependent inputs, which is a definite advantage for applications involving measurements of eddy fluxes and spectra of O3. The unit is highly specific, the only known interference being a slight quenching of the chemiluminescence by water vapor. The unit does not respond to cloud liquid water or to precipitation, and excellent performance has been obtained in the presence of these two conditions. The entire package weighs 110 kg and requires 360 W at 110 V ac (60 or 400 Hz), and 1200 W at 28 V dc.


Purpose – The purpose of this paper is to analyse the effect of cantonal social policies and cultural settings (in Switzerland) on women's and men's employment behaviour. Special consideration is given to the transition to parenthood. Design/methodology/approach – Based on data from the Swiss Labour Force Survey (SLFS) this paper conducts multilevel analyses to test individual and cantonal effects on the probability of employment and on working hours. To analyse the effect of parenthood, models for women and men with children under three are contrasted with models for women and men without children or with older children. Findings – The paper documents the persistence of gender inequality in employment linked to parenthood. How the reconciliation of work and family life can be realised for women and men strongly depends on a set of policies and cultural conditions. Moreover, individual characteristics such as education or marriage are important predictors. Research limitations/implications – A shortcoming...


The spreading of elementary statistics mainly goes on through middle school math teaching. The paper has done a comparison of senior high school math book in between China, United Kingdom, and Japan


Radio frequency identification (RFID) is an emerging technology for automatic object identification. An RFID system consists of a set of readers and several objects, with each object equipped with a small chip, called a tag. In this paper, we consider the anonymous cardinality estimation problem in an RFID system consisting of several readers. To achieve complete system coverage and increase the accuracy of measurement, multiple readers with overlapping interrogation zones are deployed. We study the problem under two different circumstances. First, we assume that the readers cannot perform interrogations synchronously. This models the case when the readers are not equipped with accurate clocks or synchronization imposes a high overhead. Under such condition, we propose an asynchronous exclusive estimator to estimate the number of tags that are exclusively located in the zone of a selected reader. By using this estimator, we propose an asynchronous multiple-reader cardinality estimation (A-MRCE) algorithm. In the second scenario, we assume that readers can perform interrogations synchronously. We propose a synchronous exclusive estimator and a synchronous multiple-reader cardinality estimation (S-MRCE) algorithm to estimate the total number of tags. For the exclusive estimators, we show that they are asymptotically unbiased and we derive upper bounds on the variance of error. We validate our analytical model via simulations. Results show that although the A-MRCE algorithm enjoys the asynchronous operation of the readers, it performs worse than the S-MRCE algorithm in terms of estimation error. Compared to the enhanced zero-based (EZB) and lottery frame (LoF) algorithms, the variance of the estimation error for both A-MRCE and S-MRCE algorithms increases linearly with the number of readers, while it increases exponentially for EZB and LoF algorithms.


Idiomaticity refers to the situation where the meaning of a lexical unit cannot be derived from the usual meanings of its constituents. As a ubiquitous phenomenon in languages, the existence of idioms often causes significant challenges for semantic NLP tasks. While previous research mostly focuses on the idiomatic usage detection of English verb-noun combinations and the semantic analysis of Noun Compounds (NCs), the idiomaticity issues of Chinese NCs have been rarely studied. In this work, we aim at classifying Chinese NCs into four idiomaticity degrees. Each idiomaticity degree refers to a specific paradigm of how the NCs should be interpreted. To address this task, a Relational and Compositional Representation Learning model (RCRL) is proposed, which considers the relational textual patterns and the compositionality levels of Chinese NCs. RCRL learns relational representations of NCs to capture the semantic relations between two nouns within an NC, expressed by textual patterns and their statistical signals in the corpus. It further employs compositional representations to model the compositionality levels of NCs via network embeddings. Both loss functions of idiomaticity degree classification and representation learning are jointly optimized in an integrated neural network. Experiments over two datasets illustrate the effectiveness of RCRL, outperforming state-of-the-art approaches. Three applicational studies are further conducted to show the usefulness of RCRL and the roles of idiomaticity prediction of Chinese NCs in the fields of NLP.


The Northern Aerosol Regional Climate Model (NARCM) is used to study the visibility and three-dimensional (3-D) evolution of aerosol distributions within the Mexico City basin. NARCM simulates transport, diffusion, deposition, and size distributions of sulphur aerosol particles in the region. The model assumes only simple sulphur oxidation, not taking explicitly into account the urban air chemistry. Rather, it focuses on detailed aerosol microphysics and 3-D optical properties. The simulation performance is compared with upper air and ground-based observations for the following specific days of intensive measurement: 2, 4, and 14 March 1997. Time series at Mexico City airport shows lower values of visibility in the morning due to a shallow mixed layer and higher values in the afternoon following the evolution of the mixed layer depth. Modeled visibility shows large dependence on cardinal direction and size distribution of particles. It is found that better resolution of particle size leads to better representation of coagulation processes and to realistic size distributions which show a characteristic accumulation mode around 0.3 μm. As a result, visibility simulations are closer to those observed at the airport location. Comparing visibility is a stringent test for the model because it requires an accurate representation of 3-D meteorological fields together with a realistic aerosol simulation.


e16617 Background: Each year, more than 18,000 randomized control trials are published and thousands of other clinical studies conducted. Despite this, systematic reviews intended to inform clinical and health policy decisions routinely conclude that evidence is inadequate or insufficient to draw conclusions. The Center for Medical Technology Policy (CMTP) developed a stakeholder-driven process to create EGDs to provide specific recommendations to product developers, sponsors and clinical researchers on designing CER studies.

METHODS
Since 2008, CMTP has piloted several EGD initiatives and worked with a team of trial and systematic review experts to better establish and standardize a formal EGD process, outlining specific steps to explicitly engage stakeholders (e.g., patients, payers, clinicians, technical experts, professional societies, regulatory agencies, federal scientific bodies, industry, compendia publishers, advocates) throughout the development phases.

RESULTS
As of 2011, CMTP has produced two oncology EGDs and others in cardiology, wound care and genomics. Development of these EGDs involved an iterative, stakeholder-driven process. Project staff conducted interviews with designated stakeholders prior to convening asymposium that: (1) discussed findings from a literature review and the interviews, (2) developed and vetted recommendations, and (3) generated a summary policy document. Draft recommendations were revised by participants and others through email, phone calls, and public comment.

CONCLUSIONS
The CMTP stakeholder-driven EGD process generates recommendations for designing CER studies aimed at generating evidence for post-regulatory decision makers. Studies that follow these guidelines provide decision-makers with reasonable confidence in understanding the comparative relationships between interventions and health outcomes, consistent with Patient Centered Outcomes Research Institute's (PCORI) mission and goals.


This study was conducted on 668 ovary from abattoir of adult ewes. Three types oocytes aspirated from mature follicles (Oocyte with cumulus cells , partial surrounded by cumulus cells ,and oocytes without cumulus cells ) it is incubated in the Co 2 incubator to maturation in TCM199 .The step of oocyte maturation previously the in vitro fertilization, therefore the investigation of oocyte in the molecular level very important for detection the oocyte quality ,so the defect in the mitochondrial gene Cytochrome Oxidase subunit 1 (CO1) may take place through the oocyte cultured in the tissue culture media. Subsequent by genomic DNA extraction by (Bioneer Kit), to investigation the goal gene, samples yielded evidence of amplified CO1 gene on the agarose gel electrophoresis. No mutation in the CO1 sequence compared with the Al-naemi sheep breed and Assaf sheep breed . The conclusion , via PCR and sequencing of CO1 gene, no differences in the oocytes through the oocyte in vitro maturation in the age 3-6 old of ewes. Introduction The oocyte is surrounded by layers of cumulus cells and attached to the granuloma cells by a stalk of cumulus cells, it is made up of an oocyte enclosed by a glycoprotein coat, the zona pellucida, and is surrounded by tight, compact layers of cumulus cells (1-2). Eukaryotic cells contain two distinct genomes, one is located in the nucleus (nDNA) and is transmitted in a mendelian fashion, whereas the other is located in mitochondria (mtDNA) and is transmitted by maternal inheritance (3). A group of mitochondrial diseases are caused by mutations of the mtDNA and inherited (4). Human oocytes and early embryos from aging, clinically infertile women contain mitochondria with ultra structural features similar to those senescing or degenerating somatic cells including vaculation swelling and mineral deposition (5). Mitochondria are organelles that play an essential role in cellular energetic metabolism, homeostasis, and death (6). ATP depletion causes a series of cell injuries including plasma membrane permeabilization, lipid degradation, phospholipase A2 activation, intracellular calcium elevation, calpain activation, loss of membranecytoskeleton linkage and alteration of function aggregation of membrane proteins. Among these pathological changes plasma membrane become permeable to macromolecules the injury of the cells become irreversible (7). Mitochondrial genome very important for fertility in the ewes, the mitochondria energy house of cell, therefore any defect in the mitochondrial genomes led to low quality of oocyte with the infertility of ewes. Mitochondrial DNA (mtDNA) has been used to study the domestication history of many species (8), and the complete mtDNA sequence of sheep has been determined 660 nucleotides base pairs (bp) (9). Mitochondrial DNA content is critical to fertilization outcome and serves as an important marker of oocyte quality (10-11), The mean mtDNA copy number for the fertilized oocytes was 250,454, whereas for the unfertilized group it was 163, 698. There were significant differences for mtDNA copy number between the male factor infertility female factor infertility unfertilized oocytes and between unexplained infertility and female factor infertility group (12). Mitochondrial DNA copy number is an important indicator of oocyte developmental competence (13) COXI (NADH uniquinone oxidoreductase), this complex consist of 42 or 43 sub unit (14). Complex 1 of the respiratory chain consists of 41 subunits, 7 of which are encoded by mtDNA (15). Materials and Methods Ewes' genitalia collected from abattoir, the age of ewes between 3-6-years old. The best age of oocyte quality between 3-6 years (16), the study included oocyte recovery from 668 ovaries, the ovaries transmitted by cooler container at 22 C washed with preserved by sterile normal saline. Oocyte aspirated by needle gage 18. The oocyte recovery mixed with TCM 199 in pitry dish. The procedure was done in humidified incubators maintained at 38.5 C in air with 5% CO2 and incubated 24 hour in the Co2 incubator. In the Biotechnology of Baghdad Center of Al– Nahrian University, oocytes recovered from tissue culture media in the petri dish and washing with normal saline, mechanically rid out the cumulus cells many times aspiration until to denude the oocyte. Subsequent by Genomic DNA extracted from oocytes after oocytes maturation. Genomic DNA was amplified using the polymerase chain reaction (PCR) (17-18-19). Detection of cytochrome oxidase subunit 1 gene was conducted by using primers for amplification of Ovis CO1 gene. A fragment 660 bp of Ovis CO1 ( 20) was amplified using a forward primer (Ovis CO1-F: 5-GCTGGTATCACAATACTACT-3 and a reverse primer (Ovis CO1-R: 5-TAGTCCTAGGAAATGCTGTG-3. These primer sets were supplied by IDT (Integrated DNA Technologies) company, Canada. Sequencing of CO1 gene was performed by national instrumentation center for environmental management (nicem) online at (http://nicem.snu. ac.kr/main/?en_skin=index.html), biotechnology lab, machine is DNA sequencer 3730XL, Applied Biosystem), Homology search was conducted using Basic Local Alignment Search Tool (BLAST) program which is available at the National Center Biotechnology Information (NCBI) online at (http:// www.ncbi.nlm.nih.gov) and BioEdit program. Result and Discussion Oocyte Collected from ewes ovaries obtained from abattoir, it is aspirated from mature follicle (21). There are


Over the course of a decade, studies were conducted throughout northern Illinois and northeastern Indiana to locate old settler cemeteries containing prairie vegetation and to determine their species composition. Of the 824 cemeteries investigated in 42 counties in northern Illinois and in 20 counties in northwestern Indiana, 150 contained some prairie species. Of the 44 cemeteries that had sufficient prairie species to warrant study, 29 were silt-loam prairies, 14 were sand and silt-loam savannas, and one was a sand prairie. A total of 180 species of prairie plants were found in the 29 silt-loam cemetery prairies, belonging to 43 different families. The Compositae had the most representatives with 48 species (26%), followed by Gramineae with 15 (8%), Cyperaceae with 14 species (7%), and the Leguminosae had 12 (6%) species. The soils present in these cemeteries had deep A-horizons, and most showed no evidence of ever having been plowed. They represent a cross-section of the soil types found in northern Illinois and northwestern Indiana, with loess soils in the west and till soils in the east. This difference in soil type influences the relative abundance of some prairie species.


One of the biggest challenges in future application development is device heterogeneity. In the future, we expect to see a rich variety of computing devices that can run applications. These devices have different capabilities in processors, memory, networking, screen sizes, input methods, software libraries, and etc. This creates a challenge to developers on how to make their applications available on as many types of devices as possible. We also expect that a future user is likely to own many types of devices. Depending on the situation he/she is in, a mobile user may choose to switch from one type of device to another type of device that brings the best combination between the need for functions and the ease of mobility (size and weight). Based on this scenario, we believe that there is a need for an application framework that can both assist developers to build applications that can run on heterogeneous devices and allow a user to move/migrate a running application among heterogeneous devices in an effortless manner. We define a seamless application to be an application that can run on heterogeneous devices and migrate among heterogeneous devices. In this paper, we present the challenges and the design of our seamless application framework called the Roam system.


In this paper we review the change that the educational and child rehabilitation system of children with psychomotor deficits has had to further adapt due to the COVID- 19 pandemic, explaining the importance of early care with the support of computer technologies. Because of the health emergency, many patients with a motor disability couldn't assist to the places that provided therapy services of various kinds, joined to the fact that therapists also had to avoid crowds in their rehabilitation centers and thus not spread the virus in this population so vulnerable. A solution is shown creating a digital ecosystem that allows interaction between all the actors in the process, such as children, parents or guardians, therapists, doctors, and specialists, and also some related works are mentioned that offer a broader perspective of the scope that this technological approach has been generating. The proposed solution is tested in a study case at the APPAC Association incorporating an agile methodology approach disclosing important results with the use of technologies and to work on in the future.


Clustered regularly interspaced short palindromic repeats( CRISPR),which provides effective resistance against foreign nucleic-acid elements has become a hot spot in the research of bacteriologists both at home and abroad. On the basis of introducing the research history,distribution clsssification,structure and characteristics,the mechanism and application prospects of CRISPR-system were reviewed.


Emotions play an essential role in decision making, managing, perceiving and learning and influencing rational thinking process of humans. Emotions are also important in teaching and learning and often find expression in particular ways, such as interactions with others, our interest and motivation in learning. The influence of emotions on learning is still under-emphasized. Continuous and increasing exploration of the complex set of parameters surrounding online learning reveals the importance of the emotional states of learners and especially the relationship between learning and affective behavior. This study aims to recognize learners' affective behavior in real class room environment and relate them in to the e learning environment. The proposed actions were based on the experiment carried out among the Sri Lankan university system regarding the learner behavior during teaching and learning. The results of the experiment have been used for the new developments of the e learning courses and there by the performances of the e learners will enhance accordingly.


Objective To explore the pilot fermentation procedure of recombinant E. coli strain containing two plasmids as therapeutic HBV DNA vaccine.Methods Transform the recombinant plasmids pcDNAS2.S(pS2.S) and pcDNAIIF(pFP) constructed by the authors to E. coli DH5α to obtain recombinant E. coli strains DH5α/pS2.S and DH5α/pFP respectively.Test the genetic stabilities of the two strains during subculture by calculating the copy number of plasmids.Determine the composition of medium by shake-flask culture.Optimize the fermentation parameters of the two strains in 30 L fermentor by altering medium,culture time and the mode of fed-batch.Ferment 3 consecutive batches of recombinant strains in 50 L fermentor by the optimal fermentation procedure.Meanwhile,explore the plasmid losing rate and the proportion of supertwisted plasmid DNA during fermentation.Results The copy number of plasmids of recombinant strains DH5α/pS2.S and DH5α/pFP were stable during subculture for 30 passages.The optimal medium for fermentation was that using glycerol as a carbon source;the optimal culture time was 10 h;the optimal mode of fed-batch was gradient feeding at a constant rate.By using the procedure,the wet weight,plasmid content and proportion of supertwisted plasmid DNA of fermentation product reached 58.0-71.8 g/L,1.11-1.58 mg/g bacteria and more than 93% respectively.Conclusion A stable pilot fermentation procedure of recombinant strains DH5α/pS2.S and DH5α/pFP was developed.It laid a foundation of large-scale production of therapeutic HBV DNA vaccine.


The production practice is an important step in university teaching,with the development of Teaching Reform in Higher Educational Institutions,the production practice of university is imperative.Thus,this article tries to discuss the reform about the pattern,contents,management and test of the production practice in order to heighten effect,improve quality and cultivate the abilities of students' creativity and practice.


Response of Cladophora to different P and N regimes under otherwise non-limiting conditions in cultures of artificial seawater suggests that growth rates would be limited in the field by P and N concentrations in the water column above the algae, but not in the algal bed. Treatment with P over the range 0 to 0.25 mg l super(-1) (with 5.0 mg l super(-1) N) and N over the range 0 to 5.0 mg l super(-1) (with 0.5 mg l super(-1) P) produced yields proportional to increasing concentrations.


Broadening of spectral lines combined with large and heteroscedastic noise contributions constitutes an important problem in analytical chemistry. Reduced interpretability and artefacts in further data analysis make deconvolution methods necessary. A new robust deconvolution method (RHEMEM) based on the principle of maximum entropy is proposed in order to effectively handle the presence of heteroscedastic noise. Other deconvolution methods such as Jansson's method, Fourier self‐deconvolution and LOMEP are also studied with respect to their ability to handle heteroscedastic noise. A systematic simulation study is used to compare the performance of the new method with the reference methods. They are evaluated according to reconstruction performance, robustness and the ability to work without manual input. Copyright © 2005 John Wiley & Sons, Ltd.


The mechanisms underlying the secondary recrystallization process in connection with the production of grain-oriented silicon iron have recently been clarified, throwing light on the microstructural parameters and the relationships which control the development of the final orientation. In particular, the interrelationships among grain growth, texture, and the presence of second-phase particles and/or segregating atoms has been quantified. The conditions which cause drastic deterioration in magnetic properties are analyzed here in terms of simple microstructural parameters, namely, the inhibition factor, which describes the amount of restraining force on grain growth, and the effective grain radius, which takes into account the driving force caused by grain boundary curvature and microstructural heterogeneity. It is shown that several independent process variables contribute to the modification of the microstructural parameters responsible for the secondary recrystallization instability and therefore for the magnetic properties. >


The modern market of goods and services is so saturated with offers from various companies that it is becoming increasingly difficult to attract and retain the attention of consumers. Therefore, marketers, today are searching for new tools to promote products and services, which would provide a sustainable result and would give the opportunity to constantly receive a positive effect through the growth of sales volumes. In the last decade, such a tool is event-marketing, which is a branch of professional marketing and includes a wide range of marketing activities and events aimed at promoting a product or service, as well as modeling the behavior of the target audience. 2022 was a year of challenges and economic imbalance for the world economy. As a result, companies are operating in an unstable environment and have to adjust to rapid changes in the external environment. Corporate events within the framework of event- marketing become a popular and quite effective way to influence the marketing environment of the company and allow to carry out a gradual promotion of the brand, the values of the company, and its ideas not only for the external audience but also for the company's employees. Moreover, measures of event marketing can be directed not only at product promotion but also at the motivation of employees to work more effectively, to feel themselves as a part of a team, etc. In this context, event- marketing becomes a more attractive tool, as it will allow to quickly define the conditions for further development of the company and its product, as well as to create an information occasion to attract the attention of the audience. At the same time, it should be noted that email marketing is also one of the most expensive tools for product promotion, given the objective need to measure its effectiveness and efficiency using financial instruments. As a whole, the complex preparation of measures of event-marketing and careful estimation of its productivity will allow to define in full prospects and scenarios of the behavior of the company at the market.


ABSTRACT This article offers a methodology for conducting large-scale audience analysis called "big data audience analysis" (BDAA). BDAA uses distant reading and thin description to examine a large corpus of text data from online audiences. In this article, that corpus is approximately 450,000 online reader comments. We analyze this corpus through sentiment analysis, statistical analysis, and geolocation to identify trends and patterns in large datasets. BDAA can better prepare TPC researchers for large-scale audience studies.


We study ionization of muonic atoms and dissociation of muonic molecular ions ( dd μ ) in superin- tense laser fields. We predict that the bond breaks by tunneling at an intensity I > 10 21 W/cm 2 . Ionization of the muonic atomic fragment occurs at a much higher intensity, I > 6 × 10 22 W/cm 2 . Since the field controls the dis- sociating deuteron, it can force the deuteron return and thus the ion- μ -atom recollision triggers a controlled (timed) nuclear fusion with subcycle precision. The recollision time and energy are shown to concur with clas- sical models.


The measurement of the dynamic power consumption is a very important task for the characterization and optimization of an energy-autonomous system. In this paper a measurement system is presented that allows the simultaneous measurement of three current ranges from 1 µA to 30 mA at a sample rate of 1 MHz with a selectable supply voltage in the range of 1.8 V to 3.3 V. With this system the full range of low to high power consumption is covered with a high resolution in time, as it is present in a wireless sensor node during data acquisition and wireless communication, respectively.