Dasatinib is one of the second-generation tyrosine kinase inhibitors (TKI) that is taken orally and has antiproliferative activity against chronic myeloid leukemia (CML). Dasatinib/hesperidin loaded-SLNs were synthesized in-house using a high-shear homogenizer and optimized by central composite design (CCD). Oral bioavailability and in-vivo anti-leukemic potential of developed dasatinib/hesperidin-loaded-solid lipid nanoparticles (SLNs) were determined using intravenous injection of leukemia cells in mice model. Dasatinib was administered as pure drug (suspension) and SLN formulation in leukemic mice modal. The pharmacokinetic profile was studied and compared with drug suspension using HPLC. Results denoted mean maximum plasma concentrations Cmax as 184.52 and 390.43 ng/mL, mean Tmax as 2 and 4 hours, mean half-life as 4.63 and 8.06 hours., for pure drug (suspension) and SLN formulation, respectively. The mean area under the curve (AUClast) was 1080.94 and 3669.49 hr*ng/mL for the same. SLN also showed statistically significant survival. A comparison of SLN and free drugs revealed that SLN was more effective at cytotoxicity. Therefore, the developed dual-targeted SLN formulation of dasatinib demonstrated higher sensitivity of cells to the drug entrapped in SLN than the drug suspension.


Abstract Objectives: The Food and Drug Administration discourages the casual sharing of human milk because of the risk of pathogen transmission. No information is currently available on the prevalence of this practice. The purpose of this mixed-methods observational study is to describe the size and activity of online milk sharing communities. Materials and Methods: Data for 3 months were extracted from nine public Facebook pages that facilitate the exchange of human milk. The numbers of participants, interactions, and comments were analyzed. Results: We observed 954 individuals participating in milk sharing. The number of interactions per individual ranged from none to 16 (mean, 1.74±1.65). Top reasons that participants requested milk included "lactation problems" (69.4%) and "child health problems" (48.5%). Nearly half of donors were offering 100 ounces or more, which is the minimum to be eligible to donate to nonprofit milk banks. Conclusions: Milk sharing networks in the United States are active, with...


Many industries have developed new materials as substitutes for lead in solid lubricants. For example, lead bronze, a Cu-Pb alloy that has been used for slide bearings, has been replaced by a Cu alloy containing sulfide. The development of Pb-free Cu alloys has received considerable attention recently. Pb and sulfide are types of solid lubricants; in particular, MoS 2 (molybdenum disulfide) is a popular sulfide lubricant. This study focuses on a material that contains Cu 2 S. The properties of Cu 2 S as a solid lubricant are unknown. First principles (FP) and molecular dynamics (MD) are used to clarify the lubrication mechanism of Cu 2 S. The atomiclevel stable structure of Cu 2 S is evaluated by FP under specific sliding conditions. The Cu 2 S lubrication mechanism is clarified by MD using the FP results for the interatomic potential functions. It is clarified that there is a specific slip system and the Cu-S bonds that exists above and below the layers of the slip system are very strong.


Nannizziopsis mirabilis (KNU17-67) was isolated from a field soil sample collected from Jejudo in 2017. This fungal isolate was identified and described by its morphological characters and the internal transcribed spacer rDNA gene sequencing. Potato dextrose agar medium was used to study its macro and micromorphology. In addition, a molecular phylogenetic tree was constructed for its precise confirmation as N. mirabilis . This fungal isolate has not officially been reported previously in Korea.


Abstract The performance of quantitative analysis of 1D NMR spectra depends greatly on the choice of the NMR signal model. Complex least-squares analysis is well suited for optimizing the quantitative determination of spectra containing a limited number of signals ( 20). From a general point of view it is concluded, on the basis of mathematical considerations and numerical simulations, that, in the absence of truncation of the free-induction decay, complex least-squares curve fitting either in the time or in the frequency domain and linear-prediction methods are in fact nearly equivalent and give identical results. However, in the situation considered, complex least-squares analysis in the frequency domain is more flexible since it enables the quality of convergence to be appraised at every resonance position. An efficient data-processing strategy has been developed which makes use of an approximate conjugate-gradient algorithm. All spectral parameters (frequency, damping factors, amplitudes, phases, initial delay associated with intensity, and phase parameters of a baseline correction) are simultaneously managed in an integrated approach which is fully automatable. The behavior of the error as a function of the signal-to-noise ratio is theoretically estimated, and the influence of apodization is discussed. The least-squares curve fitting is theoretically proved to be the most accurate approach for quantitative analysis of 1D NMR data acquired with reasonable signal-to-noise ratio. The method enables complex spectral residuals to be sorted out. These residuals, which can be cumulated thanks to the possibility of correcting for frequency shifts and phase errors, extract systematic components, such as isotopic satellite lines, and characterize the shape and the intensity of the spectral distortion with respect to the Lorentzian model. This distortion is shown to be nearly independent of the chemical species, of the nature of the molecular site, and of the type of nucleus, but to vary significantly with the spectrometer. The potential of the method for accurate fast and fully automatic quantitative analysis is illustrated in the case of natural-abundance deuterium NMR spectra such as those of linalool and ethyl mandelate.


The story of the Aboriginal women who participated in Australias nursing history remains largely untold. In the first six decades of the twentieth century, Aboriginal people were confronted with harsh exclusionary practices that forced them to live in settlements, reserves and missions.¹ While many Aboriginal women worked in domestic roles (in white peoples homes and on rural properties), small numbers were trained at public hospitals and some Aboriginal women received training to be native nurses who worked in hospitals on settlements In this chapter, an indigenous historical lens is applied to the status of Indigenous nurses and midwives in Australia.


* Summary of Relevant Aspects of Fluid Dynamics and Chemical Kinetics * Rankine-Hugoniot Relations * Diffusion Flames and Droplet Burning * Reactions in Flows with Negligible Molecular Transport * Theory of Laminar Flames * Detonation Phenomena * Combustion of Solid Propellants * Ignition, Extinction, and Flammability Limits * Combustion Instabilities * Theory of Turbulent Flames * Spray Combustion * Flame Attachment and Flame Spread


Objective To investigate the correlation between the level of vascular endothelial growth factors(VEGF), type and disease staging in patients with acute leukemia. Methods To detect VEGF in peripheral blood, bone marrow blood and cultured bone marrow nucleared cells supernatant from different stage of acute lymphocyte leukemia(ALL) and acute nonlymphocyte leukemia(ANLL) patients. The rate of blast cells and juvenile cells in patients'marrow were assessed simultaneously and analyzed statistically. Results VEGF in peripheral blood, bone marrow blood and cultured bone marrow nucleared cells supernatant from different stage of ALL and ANLLL patient groups were significantly higher than that from the control group, but not between ALL group and ANLL group. The VEGF decreased after remission, but it was still higher than that from the control group. The recidivist group processed a highest VEGF level in all groups. The VEGF level and rate of blast cells and juvenile cells in patient' bone marrow cells showed positive correlation. Conclusion Assessment of VEGF for diagnosis and estimation of prognosis in patients with acute leukemia is of important clinical significance.


High‐temperature expansion methods have recently been used to predict the form of the divergence of the zero‐field static susceptibility χ at the critical temperature Tc. These studies have suggested that χ∼A (T−Tc)−γ, with γ=43 independent of both lattice structure and spin quantum number S. Here we argue that the proposal γ=43 for all S is unjustified; we find a slow but nevertheless clear variation of γ with S. We further point out that there exists at least one physically interesting lattice—a normal cubic spinel with nearest‐neighbor ferromagnetic B—B interactions—for which the theoretical evidence indicates that if the power‐law form of divergence is correct, γ may differ from43 by as much as 50%.


COYOTES DROWNING IN THE TREES Benjamin Page, MFA George Mason University, 2014 Thesis Director: Dr. William Miller These stories follow two related, but separate arcs taking place in the early days of the twentieth century. The first set concerns Annie Edson Taylor, a 60-year-old woman who was the first person to survive going over Niagara Falls in a barrel. These stories explore what drove her to do this, a quest for fame and a kind of immortality. The second set follows Annie's manager, Tussy, who steals the barrel to make money for himself. He has his own issues with masculinity and struggles with the idea of a changing gender landscape at this time in America, one that forces him to take a backseat to a female daredevil.


The dynamic structure factor S(q,\ensuremath{\omega}) for a commensurate layer of krypton on a model graphite surface is calculated from molecular-dynamics simulations. The simulations are carried out at a number of temperatures ranging up to 70 K to assess the thermal variation of S(q,\ensuremath{\omega}). These results are compared with a harmonic-lattice-dynamics calculation of the phonon spectra. The multiphonon content of S(q,\ensuremath{\omega}) is shown to be minor at the temperatures considered. The temperature dependence of the zone-center frequency is attributed to thermal averaging of the substrate corrugation. The results are compared with previous studies of this system and with available experimental data.


CCD receives the optical imaging of Cross Divisional Board.The decentration measurement software processes the digital image provided by Image Acquisition System.With digital imaging technology,the measurement instrument completes automatic focusing and locates the Crosshair by non-contact measurement.The method improves the measurement accuracy and efficiency and achieves a better effect.


Flocculation of bacteria w as studied in a pilot-scale activated sludge plant fed with synthetic waste water. Flow r ate, sludge recycling, dissolved oxygen concentr ation and m ixed liquor concentration were controlled and adjusted w ith the computer (figure 1). Bacterial populations were studied by isolating and characterizing bacteria from floc and disperse phases. Bacteri a were isolated b y cultivating diluted sludge samples o n tryptone glucose-yeast extract agar diluted 1:10. Isolates were separated from each other according to colony morpholog y. Bacteriophages isolated from sludge samples were used to study the eventual influence of b a c t e r i a l v i r u s e s on f l o c f o r m a t i o n a n d disintegration .


Background: Health is not bought and sold openly. Therefore, in order to understand the value of various attributes thereof, health preference researchers conduct surveys using such elicitation techniques as paired comparisons (asking, for example, "Which do you prefer?"). In the absence of external data with which to validate their findings, researchers may estimate models that are suboptimal in terms of predictive validity. Instead of conducting analyses that rely heavily on conventional practices and assumptions, Drs. Craig and Rand-Hendriksen proposed a predictive modeling competition. Aims: To engage a large group of scientists in a modeling competition in order to identify specifications and approaches to model selection that better predict health preferences. Methods: Announced in March 2016, the competition attracted 18 teams from around the world. In April, an exploratory survey was fielded in response to which 4074 US respondents completed 20 out of 1560 paired comparisons by choosing between two health descriptions (e.g., between longer lifespan and better health). The paired comparison data were promptly distributed to all 18 teams and were also posted online. By early July, ten teams had dropped out of the competition and eight teams had submitted their predictions for 1600 additional pairs and described their analytical approach to modeling health preferences. After these predictions had been posted online, a confirmatory study was fielded that included the 1600 additional pairs and 4148 additional respondents. Results: In September, the victorious team, X led by X, was announced at the EuroQol Plenary in Berlin, Germany. This team achieved the smallest chi square 4391.54, and their predictions were rejected by only 134 of the 1600 pairs (8%) in the confirmatory survey at a p-value of 0.01. (MORE) Conclusions: This crowdsourcing endeavor demonstrated the diversity of analytical approaches and highlighted the importance of predictive validity in health preference research. (MORE) Although the generalizability to specific applications is unknown, the models that are more predictive may inform and inspire debate among health preference researchers. TTO a some health that preference to health outcomes clinical as recommendations and resource allocation decisions (e.g., cost-utility analyses). After combining the problems in these prevalent descriptions with durations to create a candidate set, we applied a software package (NGENE) to select a subset set of 200 pairs by d-efficiency. (ChoiceMetrics, 2012; Norman, 2016) To select the TTO pairs, 40 descriptions were selected from the efficient pairs. Each of the efficient and TTO pairs was shown with four temporal units, creating 1600 confirmatory pairs. A full description of the process of pair selection was included in the rules of the competition and distributed in advance of team registration.(Craig and Rand-Hendriksen, 2016) All pairs are shown in the Appendix.


IN a recent television interview Emil Brunner, being invited to say who was the greatest of British theologians, named an Aberdonian, P. T. Forsyth. ' Thus the whirligig of time brings in his revenges.' Fifty years ago, when Forsyth was at the peak of his powers, he was a voice crying in the Liberal wilderness, and it was left to an agnostic, John Morley, to pronounce him ' one of the most brilliant minds in Europe '. Now history is hastening after him ; all his chief books have


IN MANY ORTHOPEDIC UNITS, almost every patient is at high risk for falling. Some facilities' protocols require patients at high risk for falling to have a bed or chair alarm in use at all times. As a result, alarms warning staff that patients are moving are sounding constantly. Despite the many


The present invention is a walker and the brake is installed is disclosed. The invention and the chair and the plurality of the main frame that is formed by the pipe bend, which is rotatably coupled to the main frame, on the upper side of the chair and the first connecting frame which connects the main frame top, at the bottom of the chair the first is coupled to one parallel to the connecting frame, the second connecting frame and the second of the main frame and rotatably engaged reinforcing frame and the main frame at a lower portion of the chair to be close to the connecting frame for supporting the chair the one according to this combined to be inserted at a side walk consisting of one or more wheels supported on the ground aids the slide and the outer circumferential edge coupled to the one side of the central axis extending from the center of the wheel, which is coupled so that the through which the main frame tube; Once the spring is secured to the upper portion of the slide tube, which is installed to pass through the said main frame; And is in close contact with the other end of the spring comprising at least one adjusting screw which is mounted such that through which the main frame; By rotating the adjustment screw may be between the top of the adjusting screw and the slide tube to adjust the compressive force of the spring, wherein the wheel is being formed is symmetrical in the upper and lower said central axis, the rim which is gradually widened in width to the edge of the wheel is formed and, wherein the reinforcing frame rotates in the inner provides a walker brake is installed such that a possible folded.


How necessary it is to read environmental issues, national agendas, and international competitiveness in relation to each other is illustrated by a recent climate change conference held in Bali, the United Nations Framework Convention on Climate Change, 3-14 Dec. 2007. Meant to supply only a guide to negotiating an international treaty in Copenhagen in 2009, the conference nonetheless involved intense "wrangling" accompanied by feelings, in some participants, of anger and disappointment (Jowit 2007). Its conclusion a day later than scheduled "despite several night-time sessions" suggests how difficult negotiations were among national representatives seeking to address global environmental concern  without losing economic advantage for their home countries or opportunity for economic gain (Jowit 2007). The main blocs formed among 'developed' and 'developing' nations, to use the prevalent terminology, with a major split within the 'developed' bloc between the European Union and the United States. Such terminology, of course, is problematic not least for how it masks enormous differences in actual conditions (China and Rwanda, for example, both claim status as 'developing' countries).


An approach for estimating and classifying backlash clearance fault condition in hydraulic actuators is presented. Three networks (ADALINE network, a nonlinear neuron network, and multilayer perceptron network) are trained and applied to an experimental hydraulic system to identify the gap between an actuator pin and a load mass. The networks are trained on five clearance gaps of widths 1, 7, 12, 25, and 40 thousandths of an inch. They are tested on three clearance gaps of widths 10, 20, and 35 thousandths of an inch. The multilayer perceptron network performed very well in all testing. The other two networks did not perform well, except for small gaps.


Conflicts between transcription and cohesin-mediated loop extrusion can majorly influence 3D chromatin architecture but whether these structural changes affect biological function is unknown. Here, we show that a critical step in antibody class switch recombination (CSR) in activated B cells, namely, the juxtaposition (synapsis) of donor and acceptor switch (S) recombination sequences at the immunoglobulin heavy chain locus (Igh), occurs at the interface of a de novo topologically associating domain (TAD) boundary formed via transcriptional activity at acceptor S regions. Using Tri-C to capture higher-order multiway chromatin conformations, we find that synapsis occurs predominantly in the proximity of distal 3' CTCF-binding sites and that this multiway conformation is abolished upon downregulation of transcription and loss of the TAD boundary at the acceptor S region. Thus, an insulating de novo TAD boundary created by the conflict between transcription and loop extrusion plays a direct role in the mechanism of CSR.


I. Introduction Recent results of high acceleration experiments at the University of Washington ram accelerator are presented. Ram accelerators can currently accelerate projectiles up to a velocity of ~ 2.7 km/s, however, many of the potential applications for ram accelerators are dependent on achieving even higher velocities. A research effort is currently underway to maximize the velocity capability of the University of Washington ram accelerator by increasing the sustained acceleration in each stage. For thermally choked operation, thrust will be higher at lower Mach numbers and with propellants having higher levels of chemical energy release. Acceleration at a given thrust can be increased by decreasing the mass of the projectile itself. These characteristics of ram accelerator operation are exploited to demonstrate high velocity capabilities. Previous research into geometry effects identified a low mass projectile configuration which can be accelerated via the thermally choked operating mode to the Chapman-Jouguet detonation velocity. A technique was developed which identifies high acceleration mixtures in relatively few experiments, by comparing the Mach number, chemical heat release, and theoretical acceleration level over a stage of a given length. This technique is utilized to achieve record levels of sustained acceleration. Experiments were performed with the reduced-mass projectile in propellant mixtures of methane, oxygen and helium, staged to minimize the Mach number as the projectile travels down the tube. Average accelerations of 38,000 g over a single 2-m stage and 34,000 g over three 2-m stages have been observed, yielding velocities of 2400 m/s after 6m. These experiments demonstrate a significant improvement in sustained acceleration performance. The ram accelerator is a chemical hypervelocity launcher used to accelerate projectiles to velocities on the order of several kilometers per second.1 It operates on the same operating principles as a conventional supersonic ramjet: a system of shock waves attached to a diffuser compress a fluid to which heat is added via combustion, producing thrust. In a ramjet fuel is added after the air has been decelerated to subsonic speeds. The fuel-air mixture is burned and accelerated to supersonic conditions via a constricting nozzle throat, exhausting out the rear of the engine. In a ram accelerator (Fig. 1), a projectile with a conical nose and tapering rear section is injected into a tube filled with premixed gaseous fuel and oxidizer. The shock waves attached to the projectile compress the propellant mixture, which is then burned. The resulting pressure increase accelerates the projectile down the tube. The combustion stays with the projectile, allowing very high velocities to be attained.


Automatic diabetes retinopathy (DR) recognition can help DR carriers to receive treatment in early stages and avoid the risk of vision loss. In this paper, we emphasize the role of multiple filter sizes in learning fine-grained discriminant features and propose: (i) two deep convolutional neural networks - Combined Kernels with Multiple Losses Network (CKML Net) and VGGNet with Extra Kernel (VNXK), which are an improvement upon GoogLeNet and VGGNet in context of DR tasks. Learning from existing research, (ii) we propose a hybrid color space, LGI, for DR recognition via proposed nets. (iii) Transfer learning is applied to solve the challenge of imbalanced dataset. The effectiveness of proposed new nets and color space is evaluated using two grand challenge retina datasets: EyePACS and Messidor. Our experimental results show: (iv) CKML Net improves upon GoogLeNet and VNXK improves upon VGGNet on both datasets using the LGI color space. Additionally, proposed methodology improves upon other state of the art results on Messidor dataset for referable/non-referable screening.


Introduction: Serum uric acid has been shown to be an independent predictor of morbidity and mortality in the general population and in patients with heart failure. However data is limited on its role as predictor of short tern mortality among the patients with acute myocardial infraction (AMI). Study aimed to evaluate the role of serum uric acid as a marker of short-term mortality in Acute Myocardial Infarction Material and Methods: Sixty patients with AMI were studied prospectively in Department of Medicine/ Department of Cardiology, JA Group of Hospitals from2016 -2018. Serum uric acid was measured on day 1, day 3 and day 5 and was compared with the established risk factors including hypertension, diabetes mellitus and lipid parameters. Serun uric acid was also compared with mortality. Results: Serum uric acid was significantly decreased from day 1 (7.03±2.86) to day 3 (5.89±2.35) and day 5 (4.91±1.71) (p<0.001). No significant changes in patients with and without hypertension was noted (p=0.854). A decreasing tread was observed from day 1 to day 5 in both with and without diabetes patients (p=0.002). Patients who expired had significantly higher uric acid level as compared to patients who had survived (p<0.001). Lipid parameters had no relation with the serum uric acid levels at Day 1, Day 3 and Day 5 (p>0.05). Conclusion: Serum uric acid level can be used as a marker of short-term mortality in acute MI, and hyperuricemia may be an indicator of poor prognosis. Serum uric acid levels were elevated in acute MI patients with diabetes mellitus.


The purpose of this report was to: (1) detail the construction of a low-cost device that provides a "reference" flow waveform for pneumotachograph (PNT) calibration: i.e., the "syringe potentiometer" (SP); and to compare the accuracy (2) and practical performance (3) of "calibration curves" obtained using the SP device with other more established methods of PNT calibration, i.e., the weighted averaging (WA) and polynomial least-squares (PolyLS) methods. Volume and flow waveforms obtained via the syringe potentiometer device were validated against a motion capture system, and were deemed accurate surrogates of actual syringe volume and flows. The SP device was used to construct a "calibration curve" of a PNT by dividing the flow waveform of the syringe potentiometer by the analog output of the PNT amplifier. A total of 187 inspiratory and 187 expiratory strokes were collected. When using the entire dataset of expiratory strokes, the SP, WA and PolyLS methods together demonstrated acceptable volume and flow errors as per ATS/ERS recommendations (<±3.5% and <±5.0% errors, respectively). The "practical" performance of each method was assessed using a nested subsampling procedure, whereby volume and flow errors were evaluated as the number of strokes was increased (in blocks of 5 strokes). To this end, the SP method demonstrated superior practical performance to that of the WA and PolyLS approaches, whereby acceptable volume and flow errors were achieved after only 5 calibration strokes; the WA and PolyLS methods required 15 and 20 strokes, respectively, to achieve the same level of volume and flow-accuracy.


Harsanyi et al. discuss the preparedness of final-year students for consultation on childhood fever. As fourth-year medical students with an interest in paediatrics, this is particularly relevant and we concur with the notion that increased practical university training is required. Whilst the study was thorough, we believe a similar analysis could be proposed amongst other universities in different countries thus making it a more representative sample of medical students as a whole.


Nine synthetic compounds showed high juvenile-hormone activity vs. Ostrinia nubilalis (HUbner) when the materials were applied topically to the rearing medium. For maximum response, the larva must contact the test compound during the latter part of the last instar. Liquid formulations of the materials were extremely phytotoxic to field corn.

Under field conditions, foliar applications of 4 of the 9 compounds (formulated on elay granules) showed no apparent juvenile hormone activity vs. the 1st-generation corn borer.


The progress of viscose rayon and Lyocell fibers used as tobacco filter materials are reviewed. The perspective technical parameters,such as brightness,curling,elastic modulus,and residual sulfur etc. for viscose rayon fibers are recommended.


On line monitoring thresholds of liquid waste discharge and activity concentration of storage tank discharge of nuclear island liquid waste discharge system and conventional island liquid waste discharge system were analyzed.Total radiation dose control of liquid waste discharge system and on line monitoring demand of liquid waste discharge concentration were described.Finally,the target of liquid waste discharge concentration for Qinshan Nuclear Power Plant PhaseⅡ extension project was determined.


Abstract Incremental forming process is a relatively new process among researchers, which is yet to be implemented in automotive and aerospace industries. The researchers are studying various process strategies and methods to improve the geometrical accuracy of the parts obtained by incremental forming, because the geometry of the parts is one of the key factors holding back the process industrialization. One good method to investigate the benefits of a process strategy is by means of numerical analysis, from which the results obtained can confirm or disprove the gains of the researched strategy. The aim of this paper is to present the advantages of using a fluid under pressure as a supporting die instead of using a conventional fixed backing plate for the single point incremental forming process.


Rehabilitation device is used as an exoskeleton for people who experiencelimb failure.
Arm rehabilitation device may easethe rehabilitation programme for those who suffer arm
dysfunctional. The device used to facilitate the tasks of the program should improve the
electrical activity in the motor unit by minimising the mental effort of the user.
Electromyography (EMG) is the techniques to analyse the presence of electrical activity in
musculoskeletal systems. The electrical activity in muscles of disable person are failed to
contract the muscle for movements. To prevent the muscles from paralysis becomes
spasticity or flaccid the force of movements has to minimise the mental efforts. To
minimise the used of cerebral strength, analysis on EMG signalsfrom normal people are
conducted beforeit can be implement in the device. The signalsare collect according to
procedure of surface electromyography for non-invasive assessment of muscles
(SENIAM). The implementation of EMG signals is to set the movements' pattern of the
arm rehabilitation device. The filtered signal further the process by extracting the features
as follows;Standard Deviation(STD), Mean Absolute Value(MAV), Root Mean
Square(RMS), Zero Crossing(ZCS) and Variance(VAR). The extraction of EMG data is to
have the reduced vector in the signal features for minimising the signals error than can be
implement in classifier.The classification of time-domain features only can be applied for
three types of time-domain features are Mean Absolute Value(MAV), Root Mean
Square(RMS) and Standard Deviation(STD).Thearm movements of 60˚, 90˚ and 120˚ are
classified into their own class of degrees movements by using SOM-Toolbox for
MATLAB are visualized in U- Matrix form.


Physical training dance including both sociality dance and athletics dance is either a required course in department of physical training dance or an elective course in university.Two parts of the course is unallowed to isolate,although either of them can be emphasized particularly on according to the teaching target and teaching task,so as to maintain the integrality of the content,improve the teaching harvest and promote the comprehensive development of the physical training dance.


Let A and b be any given m # n matrix and m-dimensional column vector, respectively, and let e be the m-dimensional column vector whose components are all ones, i.e., e/p1, . . . ,1€' Rm. A prime denotes the transposition of a matrix or a vector. We define for any two vectors u/pu i€ and v/pv i€: u@v if u i@v i for all i, uBv if u@v and u4v, u>v if u i>v i for all i. A vector x is said to be nonnegative if x@0, semipositive if xB0, and positive if x>0. Moreover, we denote by pI€ or pII€ the negation of the statement pI€ or pII€, respectively.


Root rots are considered the most important forest diseases in Estonia, causing serious concern in forest management. The majority of trees infected by forest pathogens lack easily-detectable visual symptoms, making it difficult to detect decay in a tree. We assessed the general health condition of visually healthy trees in intensively managed Norway spruce (Picea abies L. Karst.) and Scots pine (Pinus sylvestris L.) stands with resistography in order to identify trees infected by root rot. We found that 8.0% of Norway spruces and 1.6% of Scots pines had well-developed internal decay on the root collar regardless of having no external symptoms of root rot. Visually healthy trees growing on permanent forest land experienced more decay than trees growing on former agricultural land. The radial proportion of decay of damaged trees was 61% in Norway spruces and 35% in Scots pines. The results suggest that resistography can be used as a reliable method for tree vitality assessment.


The article reveals the role of frustration tolerance. It is presented as an integral personal characteristic that ensures a person's ability to endure stress and maintain relative calm when faced with difficulty. It is substantiated that it is the main driving mechanism that allows a person to quickly adapt to new realities, resist various stress factors, find ways to solve life's difficulties, effectively build their lives, maintain an optimistic attitude, find the strength to make plans and move on and most importantly self-fulfilment, while maintaining physical and mental health. A high level of frustration tolerance is associated with high self-esteem, psychological stability, internal locus of control, low personal and situational anxiety and the manifestation of optimism. It is noted that frustration factors largely depend on a person's subjective experience, the uniqueness of his perception and the meaning he attributes to them, as well as the individual's general awareness of the probability of satisfying his own needs. The importance of social factors in the formation of frustration tolerance, in particular the process of its purposeful development, is emphasized. It is determined that the main prerequisite for the formation and development of frustration tolerance is the hardiness of the individual, which makes it possible to maintain effective life, even under adverse conditions and circumstances. Hardiness affects the assessment of the current situation, in particular, reduces its trauma, helps perceive any changes as a chance for improvement and personal development, allows you to predict the desired future and uses constructive coping strategies.


The invention discloses a method for measuring cantilever crane offsets including a vertical offset and a horizontal offset. The method comprises the following steps of: at an initial moment, detecting the length and spatial position of a cantilever crane; at an end moment, detecting the spatial position of the cantilever crane; calculating an included angle between the spatial positions of the cantilever crane at the initial moment and the end moment; and calculating the offsets of the cantilever crane at the end moment relative to the cantilever crane at the initial moment by using the length of the cantilever crane and the included angle. The invention further provides a measuring device realizing the measuring method, a measuring system and a crane. Through the technical scheme, the offsets of the cantilever crane of the crane are measured by using a simple method. The method is easy to operate, and has very high applicability and universality; moreover, the interferences of external factors such as wind load and the like on measuring processes and measuring results can be avoided effectively; and the controllability of the measuring processes is high, so that the measuring accuracy is high, and the working state of the cantilever crane can be grasped more conveniently, rapidly and accurately.


This paper deals with Maxwell's equations with a thermal effect, where the electric conductivity strongly depends on the temperature. It is shown that the coupled system has a global weak solution and the temperature is Hölder continuous if the conductivity decays suitably as temperature increases. Moreover, uniqueness of the solution is proved, which gives a positive answer for a open question from the previous research. The main idea for the global existence is based on deriving various energy estimates for the solution of the coupled system. Copyright © 2006 John Wiley & Sons, Ltd.


The purpose of this study was to analyse cell proliferation in the ileum before and after neonatal closure to macromolecules and to determine the effects of the sympathomimetic amine, isoproterenol (IPR), on cell cycle parameters. 8‐ and 28‐day‐old rats were employed in this study representing the neonatal periods of pre‐ and post‐closure ileum respectively. The duration of the cell cycle phases was determined by the percentage of labeled metaphases technique (PLM) with computerized analysis of the curves. The generation cycle time was longer in 8‐day‐old suckling rats (18.63 hr) as compared to the older weaned rats (11.85 hr), and most of this 6.78 hr difference was in the G1‐period (4.5 hr). Other proliferative indices were also lower in the suckling rats—mitotic index (1.9 ± 0.4% as compared to 6.7 ± 0.9%), labelling index (26.8 ± 2.5% versus 44.2 ± 2.6%) and migration rate measured as per cent labeled villus cells (8.9 ± 3.1% versus 45.2 ± 3.4%). IPR was found to inhibit cellular proliferation in the ileal epithelium of both age groups. The cell cycle of the ileal epithelium of 8‐day‐old rats was lengthened from 18.63 to 21.07 hr and 28‐day‐old rats from 11.85 to 13.98 hr. IPR produced a decrease in mitotic index from 1.9 ± 0.4% to 1.6 ± 0.4% in pre‐closure ileum and from 6.7 ± 0.9% to 5.1 ± 0.6% in post‐closure ileum. Labeling index decreased from 26.8 ± 2.5% to 20.0 ± 2.0% in 8‐day‐old rats and from 44.2 ± 2.6% to 31.1 ± 3.0% in 28‐day‐old rats after IPR administration. There were also significant differences in growth fraction between age groups and a significant decrease in growth fraction after IPR‐treatment. From the results of this study it appears that β‐adrenergic stimulation has an inhibitory effect on neonatal ileal epithelium.


The human imprint on the global environment has become so pervasive that it rivals the forces of nature in its impact on ecosystem function. We are now living in the Anthropocene with increased air, light, noise, and heavy metal pollution (Foley et al., 2005). Understanding the link between anthropogenic stressors and functional trait characteristics will be vital to predict species response and adaptability to environmental change. Especially as urban areas increase, where anthropogenic changes are highly concentrated and overlapping, investigating how multiple stressors interact to affect individuals and populations is a current research priority. Wilson et al. (this issue) levy the power of human interest in wildlife to study the effects of human-generated pollution (2021). The authors provide a timely and novel continent-level study that addresses the interaction of light and noise pollution on species abundance and response using community science.


This paper examines the suitability of the content and pedagogy of Ghanaian polytechnic syllabus in developing able and confident entrepreneur's mindset of polytechnic graduates. Based on a survey of 750 final year students, the paper explores curriculum coverage of entrepreneurship syllabus, teaching and learning methods and emphasis and respondents capacity to start a business.The results indicated weaker link between the entrepreneurship development course of the polytechnic and preparedness of graduates to create businesses, at least from the student perspective which may be largely due to the teaching and learning methods.


Summary form only. Aluminum nitride (AlN), gallium nitride (GaN), indium nitride (InN) and their alloys AlGaInN, the so called column-III nitrides are promising candidates as the material for fabrication of very short wavelength light emitters in the blue to near ultraviolet region, because they have direct transition type band structure with the bandgap energy ranging from 1.9 eV to 6.2 eV at room temperature (RT).<<ETX>>


This theoretical review is an overview of three important theories: schema theory, information-processing theory, and sociocultural theory. Second/foreign language teachers need to familiarize themselves with these theories if they want to teach culturally unfamiliar texts more successfully
 in their language classrooms. Although each of these theories can be applied to different stages of reading instruction (pre-reading, while-reading, and post-reading), schema theory is more applicable to the pre-reading stage; sociocultural theory to the post-reading activities; and information-processing
 theory to the while-reading stage if teachers choose to use text-relevant video segments. A new framework for reading instruction, as well as some implications and suggestions for language teachers and researchers, are discussed in detail.


Dyspepsia is a very common upper gastrointestinal problem and its causes may be functional or organic in nature like NSAIDS or H.pylori infection and GERD . also ,H.pylori prevalence is high in dyspeptic patients and because it was considered carcinogenic organism and cause a wide spectrum of health problems (like peptic ulcers, gastric lymphoma ,anemia and thrombothytopenia etc .) . in this study 100 dyspeptic patients investigated for H.pylori prevalence using UGIE to obtain biopsy for histopathology and urease test and revealed 90% and 89% prevalence of H.pylori respectively. also H.pylori stool Ag revealed 87%prevalence in these 100 patients and only urease positive patients ( 89 patients out of 100 dyspeptic patients) included in the study . In this study group female 50 (56.2%) male 39 (43.8%) and before treatment there laboratory investigations revealed anemia in 13 (14.6%) and thrombothytopenia in7 (7.9%) elevated liver enzymes in 6( 6.7%) elevated bilirubin in 2 (2.2%) and elevated FPS 3 (3.4%).these 89 patient evaluated after taking load regimen( omeprazole 40mg once daily ,nitazoxanide 500 mg twice daily ,levofloxacine 250 mg once daily and doxycycline 100 mg once daily ) but with extended duration (14 days ) and after 4weeks from end of treatment H.pylori stool Ag test revealed eradication of H.pylori in 79 (88.8%) and failure in 10 (11.2%) and there laboratory investigations after treatment revealed increase in HB concentration and number of anemic patients decreased to became 8 (9%) , also increased platelets number in some patients reduced thrombocytopenic patients to became 4 (4.5%) , increase in elevated liver enzymes patients in 16 (18%) and elevated bilirubin in 9(10.1%) patients and elevated FPS patiens were the same 3 (3.4%) and as a conclusion load regimen was effective and safe with some few advirse effects in treatment of H.pylori infected patients. key words : H.pylori , load regimen .


The electronic and the geometrical structures of the polymers poly-1,3,4-oxadiazole and poly-(p-phenylene-1,3,4-oxadiazole) are studied using density functional calculations. These polymers are fully conjugated, having band widths which are comparable to the more common conjugated polymers. They have however a significantly higher ionization potential, which makes them suitable hole blocking materials for organic light emitting diodes. In addition poly-1,3,4-oxadiazole is a convenient electron transport material, due to its high electron affinity. Due to the presence of the phenyl rings, the electron affinity of poly-(p-phenylene-1,3,4-oxadiazole) is much lower.


Shared energy storage, as a new business model combining energy storage technology and sharing economy concept, has the potential to play an important role in the new energy consumption scenario driven by the goal of "double carbon",. However, there are still no unified evaluation standards and methods to evaluate the development and operation of shared energy storage business models. In this regard, firstly, the basic elements of the shared energy storage business model in the new energy consumption scenario are analyzed; secondly, a comprehensive evaluation index system for shared energy storage is designed, and the definition and connotation of each index in the index system are outlined in detail; Finally, by designing the target solution, we adopt the improved approximate ideal solution ranking method to achieve the horizontal comparison evaluation between different evaluation solutions and the vertical comparison evaluation between evaluation solutions and target solutions.


Objective To evaluate the application value of multislice CT(MSCT) in the the extrahepatic bile duct obstruction. Methods Retrospectively analyze 51 cases with the extrahepatic bile duct obstruction confirmed by surgery, pathology and clinical follow-up who underwent CT examination. Of 51 cases, 41 cases were benign, 10 cases were malignant. Results For the extrahepatic bile duct obstructive lesions, the benign lesions mostly displayed as intrahepatic bile duct twigs or residual roots with light, moderate expansion, obstruction of bile duct showed funnel model change, the extrahepatic bile duct wall with ring-like diffuse thickening; The malignant lesions mostly displayed as intrahepatic bile ducts being soft in the vines, severe expansion, obstruction of bile duct was truncated or suddenly narrowed with lump, extrahepatic bile duct wall in annular had thickening limitations. Conclusion The benign and malignant extrahepatic bile duct obstruction were the characteristic CT signs, paying attention to the morphology of bile duct changes, as well as the relationship with the surrounding tissue structure, combined with clinical comprehensive analysis, can improve the accuracy of diagnosis.


The paper considers two interrelated problems: 1. Based on known characteristics of reliability under the conditions of constant load, how to find these characteristics for the case of arbitrary piecewise continuous functions of load. 2. The inverse problem consists in how to estimate the reliability parameters of a product under the conditions of constant loads, including those for small loads which correspond to normal modes, based on accelerated testing with variable (monotonically increasing) loads.


ABSTRACT The occurrence of PC considerably worsens the prognosis of cancers. The classic treatment yields an overall survival of below 5% at 5years. However, in 20% of the cases, the disease is exclusively peritoneal, and a treatment combining complete cytoreductive surgery (CCRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) has made it possible to achieve a major increase in 5-year overall survival. HIPEC is only proposed for treating residual infra-millimetric,PC and therefore, is logical and useful exclusively after CCRS. The current appropriate indications are as follows: For peritoneal pseudomyxomas (5-year OSR is above 80%). For colorectal PC (5-year OSR exceed 40%, with 18% of patients definitively cured). For mesotheliomas (the 5-year OSR is close to 58%) Current doubtful indications are as follows: For gastric tumours (the 5-year OSR is close to 15%). For ovarian cancers (OSR are very low when CCRS + HIPEC is used as a salvage treatment). For few rare PC (not detailed). Conclusion CCRS + HIPEC are the current gold standard therapy for peritoneal extension of pseudomyxoma, mesotheliomas and colorectal PC, for selected patients. Disclosure The author has declared no conflicts of interest.


The white Western self as a racial being has for the most part remained unexamined and unnamed. On the one hand, studies of racial and cultural identities have tended to view the range of potential subjects of research as limited to those who differ from the (unnamed) norm. On the other hand, whiteness has elsewhere been simultaneously ignored and universalised. ...In short, whiteness and Westerness have not, for the most part, been conceived as 'the problem' in the eyes of white Western people, whether in research or elsewhere. (Frankenberg, 1993, pp. 17-18)


The fullness of Woolf's engagement with early-twentieth-century feminism has at times been overshadowed by the prominence given A Room of One's Own, and by longstanding archival obstacles to accessing her extensive work in periodicals. This chapter aims to offer an overview of Woolf's engagement with British feminism during her lifetime, and to promote a richer conversation about how Woolf's fiction, journalism, and essays, as well as A Room and Three Guineas, reflect a sustained engagement with, contributions to, and wariness of the feminist concerns of her day. Her responses to women's suffrage, worker's rights, the legal status of married women, education, political power, economic parity, and pacifism were unified by her consistent endeavors to draw attention to patriarchy as structuring public perceptions of 'women's issues'. (125)


This paper presents a method for identifying the optimum structure of Wiener model with piecewise linearisation. The number of piecewise linear functions for estimating the static nonlinear and the maximum lag of the linear dynamic part of the Wiener model are selected by cross-validation based approach. The maximum lag and the number of partitions are selected in two subsequence steps. Three popular model selection criteria, i.e. FPE, PRESS, and CP, are considered and compared in the selection process. With the ultimate aim of compensation for nonlinearities in sensors, we have illustrated the feasibility of using the proposed method to compensate hard nonlinearities, such as discontinuous nonlinear and saturation. The results from this work can be used as a guideline of model selection for Wiener model identification and nonlinear compensations of sensor.


In this paper, the possibility of using a convolutional neural network for analyzing weld defects are considered. A program has been developed for creating a data set for training and classification of weld defects based on the publicly available GDXray database. The VGG-16 model is used for classification. The model and algorithm for training a convolutional neural network are described. Technologies of model retraining control are applied. The main method for solving the problem is to transfer training due to the small number of images for training. The resulting model was applied in a specially created program for detecting and classifying weld defects. Examples of how the program works are presented. This model classifies weld defects into 5 classes with an average accuracy of about 86%.


Sea urchin overgrazing has caused widespread phase shifts from kelp forests to "urchin barrens" on many temperate reefs, reducing habitat complexity, productivity, and biodiversity. Sea urchin removal is increasingly used for kelp restoration; however, few studies have quantified the efficiency and effectiveness of different removal methods, resulting in limited understanding of their practicality. In this study, the efficiency (removal rate) and effectiveness (proportion removed) of four removal methods were evaluated in northeastern New Zealand. We compared culling or collecting sea urchins by either SCUBA or freediving in 128 small‐scale plots (25 m2). We also evaluated the efficiency and effectiveness of culling in four large (1.6–2 ha) barren areas, scales relevant for restoration. On average, culling sea urchins was 1.9–4.4 times faster than collecting, and SCUBA was 1.5–3.3 times faster than freediving. Removal rates increased with sea urchin density, especially for culling on SCUBA, while freediving removal rates increased with experience. Effectiveness was lower in large‐scale removals (86–93% of sea urchins ≥40 mm removed) compared to small‐scale removals (98–99%), but sufficient for restoration objectives. Estimated time per area (using SCUBA culling) was similar across large‐scale removals (49–57 hours/ha), despite an almost 2‐fold variation in initial sea urchin densities (approximately 4–8 urchins/m2), suggesting area may better predict total removal time than simply number of sea urchins across low‐density ranges. While sea urchin removal provides a rapid, feasible, and effective approach to restoring kelp in urchin barrens, restoration plans need to also address the causes of sea urchin overpopulation to ensure long‐term benefits.


The book "Interracial families: tensions between color and love"by Lia Vainer Schucman, 2018, analyzes through interviews, five interracial families, seeking to understand how the issues of color, race and racism are lived and meant by different family members and transmitted between generations. It also deals with the intrapsychic and interpsychic dimensions of the experiences, to demonstrate that within these families it is possible to build strategies to face racism, and the embrace and elaboration of violence, but this is also the locus of legitimation and racist experience. At the end, he points out: i) the need to recognize the damages that cause inequality in the social experience of race and racialization of subjects; ii) racial literacy as the appropriation of a new way of being, acting and thinking to overcome whiteness. 1 Professora de Sociologia e Ciência Política da Universidade Federal de Santa Catarina UFSC e Doutoranda em Educação pela UFSC. E-mail: firstname.lastname@example.com 2 Historiadora mestra em história pela Universidade do Estado de Santa Catarina (UDESC) e doutoranda em Educação pela Universidade Federal de Santa Catarina – UFSC. E-mail: firstname.lastname@example.com


A role of serotonin receptors (5‐HTRs) in spinal rhythmogenesis has been proposed several years ago based mainly upon data showing that bath‐applied 5‐HT could elicit locomotor‐like rhythms in in vitro isolated spinal cord preparations. Such a role was partially confirmed in vivo after revealing that systemically administered 5‐HTR2 agonists, such as quipazine, could induce some locomotor‐like movements (LM) in completely spinal cord‐transected (Tx) rodents. However, given the limited binding selectivity of currently available 5‐HTR2 agonists, it has remained difficult to determine clearly if one receptor subtype is specifically associated with LM induction. In situ hybridization, data using tissues from L1–L2 spinal cord segments, where critical locomotor network elements have been identified in mice, revealed greater 5‐HTR2A mRNA levels in low‐thoracic Tx than non‐Tx animals. This expression level remained elevated for several days, specifically in the lateral intermediate zone, where peak values were detected at 1 week post‐Tx and returned to normal at 3 weeks post‐Tx. Behavioral and kinematic analyses revealed quipazine‐induced LM in 1‐week Tx mice either non‐pretreated or pretreated with selective 5‐HTR2B and/or 5‐HTR2C antagonists. In contrast, LM completely failed to be induced by quipazine in animals pretreated with selective 5‐HTR2A antagonists. Altogether, these results provide strong evidence suggesting that 5‐HTR2A are specifically associated with spinal locomotor network activation and LM generation induced by quipazine in Tx animals. These findings may contribute to design drug treatments aimed at promoting locomotor function recovery in chronic spinal cord‐injured patients.


A multitasking machine, in which a metal powder is selectively heated and fused by laser beam irradiation and the edge of the consolidated structure is cut with an end mill, has been developed for the production of injection mold. This machine has an advantage that the molding die does not have to be separated for the cooling channels. However, it is difficult to finish the internal face of cooling channels which are complicatedly located inside the molding die. This study describes a finishing performance of cooling channel with a face protuberance inside a molding die with free abrasive grains. A fluid flow in the cooling channel is calculatedly simulated, and the effect of internal face protuberance which is spirally arranged on the finishing performance is experimentally investigated. The results showed the application of the face protuberance on the internal face was quite effective for the improvement of the face condition. The internal finishing of cooling channel was also effective for the improvement of the thermophysical properties. Various types of layered manufacturing techniques have been proposed since Kodama first presented a new method for fabricating three-dimensional plastic models[1]. These layered manufacturing techniques were followed by the development of a three-dimensional CAD system and classified as being distinct from the forming and material-removal processes[2]. A variety of materials, such as polymers, ceramics, and metal powders, have been used to manufacture a range of prototypes, tools, and functional end-products[3]. Indeed, the use of metal powders in layered manufactured techniques is especially remarkable because the structures obtained are strong enough for practical use. Recently, a multitasking machine, in which a metal powder is selectively heated and fused by laser beam irradiation and the edge of the consolidated structure cut with an end mill, and which results in improved cost performance and reduced production times, has recently been developed for the production of injection mold[4]. The injection mold produced by the layered manufacturing processes has the advantage that the cooling channel can be complicatedly located by using a designed CAD model. Additionally, the injection mold does not have to be partitioned into separate block to locate the cooling channels. However, the internal face of the cooling channels obtained by the layered manufacturing processes is not uniform due to the partially molten powder, the adhered powder and the pore[5]. It is difficult to finish the internal face of the cooling channel which is located inside the injection mold. This paper deals with an internal finishing of a cooling channel located in an injection mold which is fabricated by the layered manufacturing. The free abrasive grains are used to finish the internal face of the cooling channels. A fluid flow in the cooling channel is calculatedly simulated, and the effect of internal face protuberance which is spirally arranged on the finishing performance is experimentally investigated. Additionally, the effect of internal face finishing on the thermophysical properties of the cooling channels is also evaluated.


authorities. Their focus in this book is not on the economic functions and political aspects of BITs. The outcome of investment arbitration is usually in favour of investors from the developed world and against developing countries. This may not be surprising; the BITs are entered into to facilitate foreign investment and cases are only brought when foreign investors believe they may achieve a remedy. But it is not enough to operate with this kind of assumption. A further analysis of the law and the way in which it functions is required. There are informational asymmetries, and developing countries may have entered into agreements bringing obligations they could not reasonably have foreseen. Some decisions of arbitration tribunals have developed an interpretation of standard clauses and used general principles in a way that could be seen as lacking in balance. The book clearly demonstrates that independent, leading arbitrators in a number of cases have gone to extreme lengths to avoid decisions against the United States. If the law developed in arbitral decisions requires developing countries to give up regulatory competences and to suffer review of court decisions—all essential parts of national autonomy—so should developed countries. It is for the countries to use the treaty-making process if they wish for anything else. Here the differences between the US 1994 Model BIT and the US 2004 Model BIT reflect an attempt to avoid that kind of restriction on US national autonomy but still tying down the developing country as effectively as possible. This brings other problems—both of these model BITs are very different from any outcome of multilateral processes, such as the GATT/WTO treaties or any other UN convention. The US model BITs could only be used by picking developing countries one by one. Then add the impact of the arbitration process, edging the balance even further in favour of the developed countries, and the outlook is rather bleak. This is not an equitable or balanced regime. In line with the book's high technical standards, it provides two comprehensive Tables of Cases and Treaties and 12 appendices, including the UK, USA (1994 and 2004), Germany, Sri Lanka, France model BITs, as well as the ASEAN Agreement and World Bank Guidelines. In addition to the first-rate scholarly legal analytical treatise that takes up the major part of the book, these appendices provide a highly practical and unique tool for anyone involved or interested in the topic.


Based on the theory of infrared spectrum,the infrared analyzer system of unregulated exhaust from methanol-fueled vehicles is described.This system is mostly applied to analyze the concentration of methanol,formaldehyde,acetaldehyde and benzene and to rectify the result caused by entironmental temperature and air pressure.By use of C language a analyzer software system is developed.Using the analyzer inspection results are instantly displayed and transmitted to PC for further data analysis and processing.


Process management is a strategy that organizations adopt to enhance institutional performance, however within public bodies, although it has been adopted this type of model to improve administrative efficiency through a comprehensive set of standards, continue to be cases of corruption, inequality and administrative inefficiency, showing that this problem could be related to the improper practice of those exercising public functions in terms of compliance misunderstanding of constitutional principles and their application, that is an issue of public ethics.


In the field of human-centred design, user experience (UX) is one of the key factors that make similar products differ in popularity among users. The more holistic one can depict UX, the more specific one can derive product requirements. One promising way to achieve good UX is user integration into product development. However, this is an open concept. By analysing recent research papers, this exploratory study gives some clues to understand the reality of UX research and practice in product development. It turns out that user integration is not necessarily the same as integrating users.


In his seminar on ethics Jacques Lacan suggests there exists a 'filiation' between Freudian psychoanalysis and a 'new direction of thought' that starts with Luther's conceptualization of 'a hatred that existed even before the world was created', and is then further continued in Calvinism. In this article this thesis is explored. The author argues that there is not only a familiarity between the protestant doctrines of predestination and Freud's reconstruction of prehistoric events, but also that Lacan's project on ethics and his elaboration of desire, superego and morality shows an affiliation with Calvinist thought on the nature of conscience and the longing for restoration of a lost image of God.


ABSTRACT This article analyses the state of democracy in the world in 2019. We demonstrate that the "third wave of autocratization" is accelerating and deepening. The dramatic loss of eight democracies in the last year sets a new record in the rate of breakdowns. Exemplifying this crisis is Hungary, now the EU's first ever authoritarian member state. Governmental assaults on civil society, freedom of expression, and the media are proliferating and becoming more severe. A new and disturbing trend is that the quality of elections is now also deteriorating in many countries. Nevertheless, there are also positive signs: pro-democracy protests reached an all-time high in 2019. People are taking to the streets to protest the erosion of democracies and challenge dictators. Popular protests have contributed to substantial democratization in 22 countries over the last ten years – including Armenia, Tunisia, and Ecuador. This was before the Covid-19 pandemic. Responses to the crisis, including many states of emergencies, risk further accelerating autocratization.


The planning of Fuzhou San Shan line of sight traverse is analyzed.The method of building DTM and 3D structure mode is proposed on the base of spatial data and ArcGIS9.0.


At the Seventh Review Conference of the Biological and Toxin Weapons Convention (BTWC) in December 2011, a working paper submitted by France sought to initiate debate on the potential of developing a peer review system for the BTWC to build confidence in the implementation of the Convention. The concept of peer review has precedent in the activities of a number of other international organizations, yet the objectives, format, participants and structure of peer review mechanisms vary. Accordingly, this report seeks to take forward this debate by looking at what peer review is; how it works elsewhere; how it could be applied in the context of the BTWC; what would be required to move forward; and what possible advantages or disadvantages a peer-review process would confer to the BTWC in light of the Convention's recent history


In this article, we focus on the subject of the show garden and place for path in the garden, in particular its forms and functions in space and meaning. The form and function of path was examined on the basis of selected, representative examples of historical gardens and contemporary show gardens of the festival in Chaumont-sur-Loire. The results showed that a path is the leading element of every garden, and its form has a decisive influence on the composition of the entire space and allows you to note content. Based on the research results, road system diagrams in historical gardens were developed and model concepts for show gardens inspired by the history of gardens were developed. The currently very touching topic of Quarantine has become the leitmotif of the garden content.


The inclusion of students with disabilities in the education system results in content or assessment accommodations to suit the students' special needs and to ensure they have acquired the objectives listed in the curriculum. In this paper, we aim at proposing different ways to accommodate a university English language test to a partially blind student who used text-to-speech tools (TTS) in order to provide them with accurate assessment. To carry out this research, the student has been monitored throughout the course to see which accommodations fit their1 needs best. All in all, we have observed that read-aloud accommodations lead to a better inclusion of the partially sighted student and better performance.


This licentiate thesis deals with the influence of transient loading, at high pressures, on the pressure-dilatation relation and frictional properties of lubricants. A Split-Hopkinson pressure bar ...


A water model for simulation of 1050 mm mold is established to investigate the effects of SEN structure, casting speed, immersion depth and other parameters on the fluctuation of the liquid level in the mold, the impact depth of the steel stream and entrapping of the flux, and compare the influence of different structure parameters and operating parameters on the flowing field in the mold in order to find out the best suitable compromise between the structure parameters and the operating parameters and then use them as the theoretical basis for SEN design. Actual results in Anyang Steel Works show that the rejected product rate has cut down to 0.6 % from 1.5 % since installation of the optimized SEN in the continuous slab caster in the Steel Works.


On the basis of the asymmetric distortion from asphere measurement by a Computer-generated Hologram(CGH),three basic distortion models were analyzed,and an effective correction method for asymmetric distortion was proposed.By using a few fitted parameters,the method can correct the asymmetric distortion accurately,reduce data point pairs needed by distortion correction and can avoid over-fitting effect.Furthermore,the distortion of whole interferometric system was simulated,and its distortion was corrected by the proposed method.The simulating result shows that the relative residual of the correction is less than 0.2%.Finally,an off-axis CGH was designed and fabricated to verify the reliability of the correcting method and an asphere surface was tested with this CGH.Then,the correcting method mentioned above was used to correct the testing result,and the correcting result was taken to fabricate the asphere iteratively.The experiments show that the aspheric surface figure converges at 1.8nm RMS(Root Mean Square)eventually.These results verify the reliability of the correction method.


The drought resistance of five cultivars seeds and seedlings of tall fescue ( Festuca arundinacea Schreb):Houndog V?CrossfireⅡ?Oasis?MustangⅡ?Dixiegreen,was tested by examining their root length,root/shoot length,root weight,electrical conductivity under drought stress simulating by different concentrations of PEG.The results showed that the ranking changed to CrossfireⅡHoundogV?Oasis?MustangⅡ?Dixiegreen,but the drought resistance of HoundogV is little better than that of the other three cultivars.It also showed that it is viable to evaluate drought resistance by root length,root/shoot length and root/shoot weight.


Abstract : In 1986, the US Army published a revision of FM 100-5, Operations, that, for the first time, clearly linked military theory and its doctrine. In this manual, a term defined by Carl von Clausewitz as the hub of all power and movement, the center of gravity, is introduced and defined as a key to operational design and applicable to all levels of war. This study examined the applicability of Clausewitz's center of gravity at the tactical level of war. A complementary concept, the decisive point, as defined by Baron Antoine Henri Jomini, was also examined and a linkage established to the center of gravity. Joint doctrine as well as the doctrine of other military services and the former Soviet Union were reviewed to determine the validity of the concept outside the Army. Two tactical level operations, the 1st Marine Division in OPERATION CHROMITE, the landing at Inchon, Korea and the subsequent capture of Seoul, and the 24th Infantry Division (Mechanized) during OPERATION DESERT STORM, were examined to determine the utility of a tactical center of gravity. A center of gravity is a source of strength for the enemy force and is normally attacked indirectly through decisive points. It is decisive points that are attacked by tactical commanders as part of the operational commander's plan to destroy or neutralize the enemy's center of gravity. The conclusion of this study is that Clausewitz never intended his analogy of center of gravity to be used at the tactical level of war. This study recommends that FM 100-5, as well as Joint and Sister Service doctrine, be revised to restrict the use of center of gravity to the strategic and operational levels of war and further develop the inherent relationship between center of gravity and the decisive point.


Silver nanoparticles (AgNPs) offer a broad range of high commercial value applications. However, current techniques to synthesize AgNPs using chemical and physical approaches are toxic to the environment and not cost-effective in the long-term. Therefore, utilization of green biological synthesis technique to produce AgNPs is one of the solutions. In this study, marine polychaete Diopatra claparedii was used to investigate its potential in synthesizing AgNPs. Specimens were collected from tidal flats adjacent to the mangrove forest in the west coast of Peninsular Malaysia and divided into two groups: freshly prepared (acclimatized in aquaria) and frozen (kept in the freezer) samples. Samples from both groups were cut, finely pulverized, filtrated, and mixed with silver nitrate (AgNO3) at room temperature. Colour changes were recorded after 24 hours, 2 weeks, and 8 weeks of incubation. Formation of AgNPs was quantified using UV-Vis spectroscopy analysis, where surface Plasmon resonance (SPR) peaks were observed in the range of 400–440 nm, confirming the formation of the AgNPs. Subsequently, the synthesized nanoparticles were validated using scanning electron microscope. AgNPs showed weak antibacterial activity because of aggregation. Further studies are required to confirm the findings.


Urgency of the research. In recent year headily internal tourism collects turns and a requirement is sharply tested in development of industry of hospitality. One of its important components is the restaurant economy, which affects the growth of the socio-economic level of the country. In connection with this, there is a need to study the demand for products and services of restaurants. Target setting. Quality of restaurant services abandons the most proof emotional impression in memory of tourist. Therefore the analysis of demand on products and services of establishments of restaurant economy must help to de fine basic problems and educe ways for upgrading. Actual scientific researches and issues analysis. The results of the study of various aspects of the development of the restaurant industry are described in the works N. V. Smirnova, N. O. Pyatnitskaya, I. V. Scavronskaya, O. D. Timchenko, Т. І. Tkachenko, G. V. Chernov, E. Gheribi, E. Kwiatkowska, G. Levytska, etc. Uninvestigated parts of general matters defining. Without regard to considerable scientific works from this range of problems, her separate aspects, in particular the modern state, demand on services and progress of restaurant economy of Ukraine trends constantly change and need a further scientific study. The research objective. The aim of the article is research of demand on services of establishments of restaurant economy, that placing in there sort zone of the Kherson area. The statement of basic materials. With the aim of determination of actual development of restaurant business on Kherson by us a study of demand was undertaken on services of establishments of restaurant economy. Factors that influence on a decrease in demand and basic problems of enterprises of feed and possible ways of their removal are certain. Conclusions. A market of sanatorium-resort services of Kherson is potentially attractive, but there are considerable defects that need correction.


Hydrogeological inverse modeling is used for integrating data and calibrating subsurface model parameters. On one hand, deterministic approaches are relatively fast but fail to catch the uncertainty related to the spatial distribution of model parameters. On the other hand, stochastic inverse modeling is time-consuming and sampling the full high-dimensional parameter space is generally impossible. Even then, the end result is not the inverted model itself, but the forecast built from such models.


Systemic lupus erythematosis (SLE) is an autoimmune disease characterized by the presence of multiple autoantibodies. Detecting the expression of CD antigens is supposed to be novel diagnosis methods. Therefore, the aim of current study was to investigate the importance of 2 markers (CD69 and CD73) on T-cells in the diagnosis of SLE; using flowcytometric analysis. The study was carried out on 30 healthy subjects (control), 42 patients with active SLE and 26 patients with active SLE + HCV. Blood count markers were significantly reduced while serum creatinine and ANA index significantly elevated in patient groups compared to the control. CD69 and CD73 were quantified using flowcytometric technique. The first was significantly increased in both SLE group and SLE+ HCV group compared to control. A reverse pattern was obtained with CD73 that was decreased in patient groups. Collectively, flowcytometric technique provided an accurate and reproducible tool for determination of 2 new markers CD69 and CD73 on T cells. The first marker CD69 exhibited good ability to predict the presence of SLE and the second one CD73 exhibited excellent ability to predict the absence of SLE in patients with or without HCV.


Nanosilica-filled water-based acrylic nanocomposites with varying monomer ratio and nanosilica content were prepared by emulsion polymerization. The resulting resins were coated on ceramic, steel, and glass substrates and the scratch resistances were measured. The relationship between the scratch resistance and the composition was observed to be influenced by the nanosilica concentration, adhesion strength to substrate, monomer ratio, and the glass transition temperature of the coating. The highest scratch resistances were obtained when a 0.46 mole percent methyl methacrylate and a 6.2 weight percent (wt%) nanosilica were used.


Distribution systems have become more and more complex and tend to use different legal figures to fulfill the producer's aims. One of them can be agency. From the perspective of competition law, agency holds a special status, resulting from the fact that the agent is present in two distinct relevant markets, in one representing this principal in the conclusion of a contract and in a second offering his services as an agent. This causes some practical difficulties and is interesting from theoritical point of view. The erroneous qualification of a distributor as an agent could result in fines imposed by competition authorities. However, as to the first market described above, according to an interpretation of article 101 TFEU, an anticompetitive agreement cannot be concluded between the same person which can lead to the agency being immune from the competition law requirements. It is imperative to recognize the difference, and therefore, the criteria of an application of article 101 TFEU to an agency have been indicated by the European Commission since 1962 and by the case law of the Court of Justice of the European Union. Nevertheless, the enigma is far from being resolved since the proposed solutions tend to be incoherent. One of them concentrates on the single economic entity doctrine. Other solutions refer to an auxiliary theory whereby. The most recent solution focuses on risks undertaken by an agent in relation to the contracts that he negotiated. The carried out analysis and solutions reached show that some other elements must be taken into account in assessing whether an agency relationship exists including an assessment of the effects of an agreement.


The purpose of this study was to determine whether the use of building function variables as dummy variables affected the duration of construction projects, together with identified measureable external factors. Multivariate regression is a technique that estimates a single regression model with more than one outcome variable. When there is more than one predictor variable in a multivariate regression model, the model is a multivariate multiple regression. Goodness of Fit (R2) of the equation regression analysist used as sensibility benchmarks. Variables are transformed to index number for unit synchronize. If the result is unsatisfied for predicting a project duration, an implementation of dummy variables could be tried if there any improvement of R2. The trial on this research, 43 data show that in first stage, five influence factors: Education Index, Technology Absorption Index, Labor Experience Index, New Technology Availability Index, and Innovation Index generate regression equation without full fill the mathematical requirement. At the second stage, by adding dummy variables based on type of building, apartment, office, hotel and other then the three type together with the five external factors, afford a good R2.


The present invention provides a miniature gas turbine engine compressor, comprising a housing, a rod, a low pressure compressor, vane, inner flange, an outer flange and a high pressure compressor, said rod extending through the housing, the low pressure compressor , inner flange and an axial high pressure compressor so sleeved on said rod, said outer flange of said inner sleeve disposed within the outer flange, said blade embedded in the inner and outer flanges method between the blue, the low-pressure compressor provided with an air inlet at one end, an end of the high-pressure compressor provided with a gas outlet, said gas inlet communicates with said outlet. Compared with the prior art, two micro gas turbine compressor according to the present invention, high efficiency, pressure ratio, the pressure ratio may reach 4.67, and the large flow capacity per unit area, the wide stable operating zone, significantly reducing production costs.


By analyzing the actual situation of English writing of China's college students and comparing thought pattern of English-speaking people with that of Chinese people,the paper tries to probe into the influence which the difference between the two thought patterns exert on their own text models.The above-mentioned difference and autonomous learning method should be taken into consideration in English learning and teaching in order to write efficiently and appropriately.


The major technical tasks that led to the definitions of operational and demonstration multiple beam antenna (MBA) flight systems and a proof of concept model (POC) are described. Features of the POC Model and its measured performance are presented in detail. Similar MBA's are proposed for transmitting and receiving with the POC Model representing the 20 GHz transmitting antenna. This POC MBA is a dual shaped-surface reflector system utilizing a movable free array to simulate complete CONUS coverage. The beam forming network utilizes ferrite components for switching from one beam to another. Measured results for components, subsystems and the complete MBA confirm the feasibility of the approach and also show excellent correlation with calculated values.


By exploring the different electoral incentives faced by mayors who are eligible for reelection (i.e. first term mayors) and those who are legally banned to run for a second mandate (i.e. second term mayors), this article provides strong evidence in favour of significant fiscal differences between both types of mayors in Brazil. As elections get close, first term mayors change their budget composition by moving from current expenditures towards capital related ones, while adjust their tax revenues losses with higher revenues from grants, so that budget balance is preserved. Moreover, first term mayors are not necessarily less fiscally responsible than second term mayors along their term in office (non-electoral years). These findings are consistent with recently developed signalling models of PFCs, where incumbents running for reelection change the composition of the budget in electoral years in a fiscally responsible manner, so as to signal his levels of competence or policy preferences to rational, fiscal conservative and heterogeneous voters.


The designs of buckets, dippers and their accessories (e.g. teeth, chains and pins) are being reconsidered by manufacturers in their search for increased productivity. Improved maintenance by the users is also important and is discussed. There are tables showing USA manufacturers of such equipment.


Utilizing a high power discrete SiC-JFET developed by KEK, a switching power supply (SPS) that had a circuit topology of H-bridge was designed and constructed to drive the induction acceleration system for the KEK digital accelerator. The SPS was operated with a 38 Ω dummy resistance load and bipolar outputs of 800V and 21A were successfully demonstrated at 1 MHz. Also, the combination test with an actual accelerator cell is being conducted.


Physical agents of the workplace such as noise and light affect work performance, productivity and quality. Noise can cause insomnia, mood changes, hearing loss and, in pregnant women, fetal damage, and it can promote the development of cardiovascular disease. Poor lighting generates tear production, eye strain and headaches, and increases accident rate. From June 08 through October 23, 2009 we used digital devices to measure noise and lighting in several rooms of the Costa Rican Distance Education University. The rooms were selected because they have noisy machinery or require a particular degree of illumination (printing facilites, warehouse and library). We found that both light levels and noise are inadequate in these departments where a quiet and well-lighted environment is basic to the daily activity and health of staff and students. We recommend the installation of noise dampers, the mandatory use of ear protectors and a redesign of artificial lighting in those specific rooms of the institution.


We learn optimal instance-specific heuristics to accelerate partitioning algorithms for solving nonconvex quadratically-constrained quadratic programs (QCQPs) to global optimality. Specifically, we propose the novel problem of strong partitioning to optimally partition the domains of variables participating in nonconvex terms within a QCQP without sacrificing guarantees of global optimality. We then design a local optimization method for solving this challenging max-min strong partitioning problem. Because solving this max-min problem to local optimality may still be time consuming, we propose to use machine learning (ML) to learn this strategy on homogeneous families of QCQPs. We present a detailed computational study on randomly generated families of QCQPs, including instances of the pooling problem, using the open-source global solver Alpine. Our numerical experiments demonstrate that strong partitioning and its ML approximation significantly reduce Alpine's solution time by factors of 3 . 5 − 16 . 5 and 2 − 4 . 5 on average and by maximum factors of 15 − 700 and 10 − 200, respectively, over different QCQP families.


Multi-service SDH networks support both packet- and circuit-switched traffic. Op-timal design of such a network means to guarantee the circuit connections and configure a logicalpacket-switched topology with lowest congestion. This letter first formulates the problem as amixed integer linear programming, which achieves optima] solution but has high computation.Then a heuristic algorithm is proposed to yield near-optimal solution efficiently. Performance ofthe algorithm is verified by an example.


The aim of this study was to analyze the relationship between school psychological counselors' secondary traumatic stress and social problem-solving levels. The sample of this research was consisted of 268 school psychological counselors who were working affiliated to Turkey Ministry of National Education in Amasya, Istanbul and Samsun. Secondary Traumatic Stress Scale and Social Problem Solving Inventory were used as data collection tools in this study. As a result of the research, while there were significant positive correlations between participants' the secondary traumatic stress levels and negative problem orientation, impulsive-careless style, avoidance style dimensions of the social problem solving, there were not significant correlations between positive problem orientation and rational problem-solving style of the social problem solving. Another finding of the study, as psychological counselors' level of social problem solving increased, secondary traumatic stress levels were found to decreased. As psychological counselors' levels of negative problem orientation, impulsive-careless style and avoidance styles were increased, secondary traumatic stress levels were found to increased. Finally, while negative problem orientation was found a positive predictor of the school counselors' secondary traumatic stress levels, positive problem orientation, rational problem solving, impulsive-careless style and avoidant style were not significant predictor of the secondary traumatic stress.


Football is a popular sport and it is estimated that women make up 22% of the 200 million players worldwide. The rate of injuries seen in women's football is similar to that in men's; ankle sprains making up most of the injuries in both sexes. However, there are some important sex specific injury patterns; in particular women are more likely to sustain an anterior cruciate ligament injury than men. Since this is an injury with major short term and long term implications the factors that might be responsible for the gender disparities have received attention. These include anatomical differences such as Q angle, neuromuscular characteristics (muscle imbalance), joint laxity and proprioception, and hormonal influences. Despite intense research fundamental questions remain unanswered so that, as yet, appropriately focussed measures to reduce the incidence of ACL injuries in women cannot be taken.


Achievement tests have shown clearly that the facts learned in any school subject are soon forgotten, and educators have consistently echoed Inglis in stating that the important outcomes are not the facts but the attitudes--or at least that the attitudes are of equal importance. Thus, Kelley writes: "We must surely assert that one of the important outcomes of education is the establishment of what we think of as correct attitudes ..... All will grant that development of and changes in attitude take place as the school years roll by." Referring to Thurstone's scales, he declares: "It is very feasible to measure the changes that take place in individuals as a result of, say, a year's instruction in some school subject."2 There is little experimental proof for the assumption that attitudes are formed or changed as a result of high-school courses. Some studies which cast a little light on the theory have been made in the field of the social sciences. Jones gave a test of opinions on social questions to college students and concluded that college training has slight effect on students' opinions.3 Symonds prepared a list


A multiple repass system, utilizing an in-line switching valve and suitable for use with small-bore glass open tubular columns, is described. The advantages of the system, which include higher OPGV, large plate numbers and optimization of column "length", are discussed.


The invitation to Eilean Ni Chuilleanain, Bernard O'Donoghue, and Frank McGuinness to contribute the following set of papers to the Irish University Review was prompted by the 2013 International Society of Anglo-Saxonists (ISAS) conference in Dublin, organised by Mary Clayton of University College Dublin and Alice Jorgensen of Trinity College Dublin. The conference was the largest ISAS gathering to date, with 210 delegates. Its theme was 'Insular Cultures', focusing on the connections between Britain and Ireland in the early Middle Ages. One of the highlights was the reading in the National Museum by Seamus Heaney on 29 July – one of his last public appearances – in which he read translations and poems inspired by Old English and Old Irish poetry, including part of his Beowulf, his very early 'Trial Pieces', whose starting point was the Wood Quay excavations of Viking Dublin, his version of the Old English 'Deor', 'Colmcille the Scribe', and 'St Kevin and the Blackbird'. It was obvious from the reading how steeped Heaney was in the medieval literatures of both islands. Heaney's Beowulf, like his translations of Henryson's The Testament of Cresseid and Seven Fables (2009), owes an obvious debt to the texts of Old and Middle English literature that were standard on university curricula on both sides of the Irish Sea up to recently. Other contemporary Irish writing also bears witness to this influence, such as the many versions of Old English poems by Irish poets in The Word Exchange (2010), edited by Greg Delanty and Michael Matto, which includes translations by Greg Delanty, Seamus Heaney, Derek Mahon, Paul Muldoon, Eavan Boland, Ciaran Carson, Eilean Ni Chuilleanain, Bernard O'Donoghue, and many others as diverse as Conor McPherson's The Seafarer (2006), Frank McGuinness's play Someone to Watch Over Me, and Bernard O'Donoghue's verse translation of Sir Gawain and the Green Knight. In order to mark the occasion of the 2013 ISAS conference, hosted for the first time in Ireland and with its focus on pre-conquest connections and exchanges


Crucial to bayesian contributions to the philosophy of science has been a characteristic psychology, according to which investigators harbor degree of confidence assignments that (insofar as the agents are rational) obey the axioms of the probability calculus. The rub is that, if the evidence of introspection is to be trusted, this fruitful psychology is false: actual investigators harbor no such assignments. The orthodox bayesian response has been to argue that the evidence of introspection is not to be trusted here; it is to investigators' dispositions--not to their felt convictions--that the psychology is meant to be (and succeeds in being) faithful. I argue that this response, in both its orthodox and convex-set bayesian forms, should be rejected--as should the regulative ideals that make the response seem so attractive. I offer a different variant of bayesianism, designed to give the evidence of introspection its due and thus realize (as I claim the other forms of bayesianism cannot) the prescriptive mission of the bayesian project.


This book covers the recent literature concerning Islamic banking and finance (IBF), focuses on the history of IBF since its inception and introduces the latest innovative concepts and practices in the field.


Delay Tolerant Networks (DTNs) are wireless mobile networks resilient to disruptions, significant latency, and incomplete paths between source and destination (S-D). Vehicular Delay Tolerant Network (VDTNs) is a subclass of DTNs. Most existing routing algorithms for VDTNs rely on predetermined rules that are inflexible to changes in node features (such as location, contact history, and node relationships). Moreover, given the extremely dynamic network architecture of the VDTN, the routing protocols must be flexible to the varying node features. Thus, the purpose of this work is to develop an intelligent routing system capable of determining the optimal routing method given a pair of S-D nodes. In this study, a novel self-adaptive routing method for VDTNs based on machine learning (ML) is proposed. Using real-time features of S-D nodes, the proposed method selects the optimal routing method. Using the Opportunistic Network Environment (ONE) simulator based on a real-world taxi trace, we evaluated the performance of our ML-based self-adaptive routing method employing various ML models. Evaluation results show that our method achieves up to 34.34% greater success rate and up to 23.75% lower average message delivery delay than existing methods.


Where in line with the artistic quality of the construction must comply with the laws of formal beauty,have the formal beauty of construction,development and the formation of human long-term through repeated practice,understanding and summed up.This article pick from the formal beauty of the building start with the basic law,and further analysis and discussion of the architects of concern to the construction principles of composition and the use of the usual methods of expression.


This article covers technological characteristics of localized soybeans, data on obtaining cereals and other types of products from them. Data based on analyzes obtained for soybean grain varieties are also provided. Physical-chemical properties of soybean varieties, proteins, fats and carbohydrates in the obtained products are widely analyzed. The macro-, micronutrients, and biologically active substances in soybeans are analyzed, and it is determined that they cause biological and physical-chemical changes in human health, and their deficiency leads to various immune-related diseases.


When milling corners in high speed, it will lead the mutation of cutting force that affects the processing quality and processing efficiency. In order to study the influence of milling parameters on milling force in the corner. Firstly, an orthogonal experimental of corner is designed to study the influence of various cutting parameters on cutting force. Axial cutting depth, radial depth, spindle speed and feed speed, as the major influence factors, impact on cutting force in corner milling. Then, a cutting force model of corner is established based on a method of orthogonal experiment linear regression. The significance test of regression equation and regression coefficient shows that cutting force model is accurate. The cutting force model is used to predict the cutting force, and then select the appropriate cutting parameters.


This document contains the alternative marriage service offered to couples getting married at the Victorian Marriage Registry. This marriage service does not include any readings, and is designed for couples with limited English or using the services of an interpreter