The horse-shoe shaped Bababudan range of low grade magnetite ore deposits in the western part of Karnataka State, India, is distributed over a length of about 25 kms. The deposits have for convenience, been divided into three continuous blocks viz., Rudragiri, Attigundi and Mahal. The huge ore reserves, proximity to the Manglore Port for possible export of iron ore and connection with Bangalore and Manglore cities through national highways, make these deposits prospective for exploration.


The variation of $S$ , the velocity derivative skewness, with the Taylor microscale Reynolds number $\mathit{Re}_{{\it\lambda}}$ is examined for different turbulent flows by considering the locally isotropic form of the transport equation for the mean energy dissipation rate $\overline{{\it\epsilon}}_{iso}$ . In each flow, the equation can be expressed in the form $S+2G/\mathit{Re}_{{\it\lambda}}=C/\mathit{Re}_{{\it\lambda}}$ , where $G$ is a non-dimensional rate of destruction of $\overline{{\it\epsilon}}_{iso}$ and $C$ is a flow-dependent constant. Since $2G/\mathit{Re}_{{\it\lambda}}$ is found to be very nearly constant for $\mathit{Re}_{{\it\lambda}}\geqslant 70$ , $S$ should approach a universal constant when $\mathit{Re}_{{\it\lambda}}$ is sufficiently large, but the way this constant is approached is flow dependent. For example, the approach is slow in grid turbulence and rapid along the axis of a round jet. For all the flows considered, the approach is reasonably well supported by experimental and numerical data. The constancy of $S$ at large $\mathit{Re}_{{\it\lambda}}$ has obvious ramifications for small-scale turbulence research since it violates the modified similarity hypothesis introduced by Kolmogorov (J. Fluid Mech., vol. 13, 1962, pp. 82–85) but is consistent with the original similarity hypothesis (Kolmogorov, Dokl. Akad. Nauk SSSR, vol. 30, 1941, pp. 299–303).


Four- to six-year-old trees were sampled from 9 to 10 stands in each of three natural populations of Monterey pine (Pinusradiata D. Don) and studied for genetic diversity at 37 allozyme loci. Among...


This paper intends to define efficiency indicators for using Social Media (SM) in a university setting, as well as to provide theoretical-practical bases for future research that takes into consideration the increasing use of SM in management processes. It is a theoreticalconceptual review of the socio-technical aspects of SM that is capable of subsidizing an evaluation methodology. It engages an applied approach, with exploratory and descriptive objectives, performing as such, a socio-technical analysis of SM, a study of university organizational guidelines for SM, an information flow analysis, and a proposal for efficiency indicators. This paper is part of a larger project entitled, "Information Flow through Social Media" which proposes as its main outcome an efficiency evaluation methodology for SM within university organizations.


This paper extends the theory of temptation and self-control introduced by Gul and Pesendorfer (2001) to allow for increasing marginal costs of resisting temptation, that is, convex self-control costs. It also proves a representation theorem that admits a general class of self-control cost functions. Both models maintain the Order, Continuity, and Set Betweenness axioms but violate Independence.


Recent results on heterostructure field effect transistors (HFETs) based upon the InAs/AlSb/GaSb material system are reviewed. Both n- and p-channel HFET structures based on the InAs/AlSb/GaSb material system have been demonstrated. The GaSb p-channel devices exhibit transconductances superior to that of any other III-V based p-channel device and show promise for future integration with an InAs channel device to form a complementary heterostructure technology. InAs channel devices have also exhibited high transconductances and low output conductances, and predicted cutoff frequencies are at least twice as high as for GaAs-based FETs. Thus, these InAs n-channel HFETs alone show promise for room temperature microwave applications. Further progress in the molecular beam epitaxy (MBE) growth and processing of these device structures should bring about further improvements in device performance.<<ETX>>


A method for continuous production of hydroxyazapirones, for example 6-hydroxybuSpirone, using a modified reactor. The products of the invention are useful as pharmaceutical agents. Patent Application Publication Jul. 28, 2005 Sheet 1 of 2 US 2005/0165233 A1 sa as a swoosses susus so you


The demographic changes in aging are occurring both nationally and globally. The dramatic increase in the older adult population raises a critical issue demanding immediate attention: how will we support and care for this growing population of older adults? In 2014, the Triangle J Council of Governments (TJCOG), located in Durham, North Carolina, developed the electronic "TJCOG Livability Self-Assessment for Municipalities" and an accompanying Toolkit as a way to help the cities and town in their region prepare for the long-term needs of their aging community members. It was based on the Stanford Center for Longevity's report: "Livable Community Indicators for Sustainable Aging in Place." The report presented a framework for how livable community characteristics influence aging in place, including measurable indicators on housing, transportation, safety, health care, supportive services, retail, social integration, and community participation. In order to provide information on the usability and effectiveness of the Livability SelfAssessment and Toolkit, and to prepare for broader implementation of these resources, a pilotstudy was conducted with five cities and towns from the Triangle J Region. Key informants were self-selected by each of the municipalities, including city or town planners or other government representatives. Participants were interviewed following completion of the electronic Assessment and six months later. The analysis of the interviews and Assessment results provided specific recommendations for enhancing the Livability Self-Assessment and accompanying Toolkit and insights into the facilitators and challenges for using the findings of the Assessment to promote community dialogue and collective planning for the rising older adult population. The results of the study conclude the TJCOG Livability Self-Assessment for Municipaities is a useable and potentially effective electronic tool to assist communities in examining their livability, identifying areas of strength and improvement. An eight step plan for change is offered on how to approach sustainable and long-lasting change. While the Assessment was developed for the cities and towns within the Triangle J Region, the possibilities for broad-based pubic health impact extend beyond the region, with state, national and international opportunities.


Abstract The logistic regression classification method uses parameter estimates that are the solution of an estimating equation. This article derives a convenient expression for the bias of a vector estimator defined by estimating equations. The expression and the results of O'Neill are used to derive the bias and the error or misclassification rate of logistic regression classification in two examples where the assumed model for logistic regression does not hold. Logistic regression classification is found to be very robust for the departures considered.


The papers and invited tutorials in this special issue were originally presented at OFC/NFOEC 2013, held in March in Anaheim, CA, USA.


*From the Millard Fillmore Hospital Research Institute, 3 Gates Circle, Buffalo, New York 14209. Supported by grants from the Heart Association of Erie County, Inc., and the John A. Hartford Foundation, Inc. A preliminary account of this study was presented at the Tri-City Heart Meetings, Buffalo, N. Y., June, 1967. The preservation and transplantation of cardiac tissue has such great clinical implications that it often has been attempted in experimental animals, in spite of the enormous complexities and difficulties inherent in such a task.


Membrane proteins are the basic constituent of a cell that manage intra and extracellular processes of a cell.About 20-30% of genes of eukaryotic organisms are encoded from membrane proteins.In addition, almost 50% of drugs are directly targeted against membrane proteins. Owing to the significant role of membrane proteins in living organisms, the identification of membrane proteins with substantial accuracy is essential. However, the annotation of membrane proteins through conventional methods is difficult, sometimes even impossible.Therefore, membrane proteins are predicted from topogenic sequences using computational intelligence techniques.In this study, we conducted our research in two phases regarding the prediction of membrane protein types and structures. In Phase-I, regarding the prediction of membrane protein types, four different ways are explored in order to enhance true prediction.
In the first part of phase-I, membrane protein types are predicted using Composite protein sequence representation followed by the application of principal component analysis in conjunction with individual classifiers.In the second part, the notion of ensemble classification is utilized.In part three, an error correction code is incorporated with Support Vector Machine using evolutionary profiles (Position Specific Scoring Matrix) and SAAC based features.Finally, in part four, a two-layer web predictor Mem- PHybrid is developed.Mem-PHybrid accomplishes the prediction in two steps.First, a protein query is identified as a membrane or a non-membrane protein. In case of membrane protein, then its type is predicted. In the second phase of this research, the structure of membrane protein is recognized as alpha-helix transmembrane or outer membrane proteins.In case of alphahelix transmembrane proteins, features are explored from protein sequences by two feature extraction schemes of distinct natures; including physicochemical properties and compositional index of amino acids.Singular value decomposition is employed to extract high variation features.A hybrid feature vector is formed by combining the different types of features.Weighted Random Forest is then used as a classification algorithm.On the other hand, in case of outer membrane proteins, protein sequences are represented by Amino acid composition, PseAA composition, and SAAC along with their hybrid models.Genetic programming, K-nearest neighbor, and fuzzy K-nearest neighbor are adopted as classification algorithms.
Through the simulation study, we observed that the prediction performance of our proposed approaches in case of both types and structures prediction is better compared to existing state of the arts/approaches. Finally, we conclude that our proposed approach for membrane proteins might play a significant role in Computational Biology, Molecular Biology, Bioinformatics, and thus might help in applications related to drug discovery.In addition, the related web predictors provide sufficient information to researchers and academicians in future research.


Present invention provides a high temperature resistant silicon bulk (≥1000 ℃) - Preparation carbon composite airgel materials. In the present invention, resorcinol, formaldehyde, 3-aminopropyl triethoxysilane as reactants, deionized water as the hydrolysis agent, alcohol is the solvent, the sol by step under the action of a basic catalyst - gel reaction preparation of wet gel, the wet gel after aging and solvent exchange, supercritical drying, high temperature heat treatment to obtain shaped refractory silicon - carbon composite airgel. The preparation method according to the present invention is simple, good controllability. Silicon prepared using the method of the present invention - carbon composite airgel airgel addresses the shortcomings of poor performance and high temperature strength of the molding is not easy to lower, airgel may be used in high temperature above 1000 ℃, having a low density, large specific surface area, large pore volume, high strength, high temperature properties.


We study the effect of Efimov physics (in the few-body sector) to the spectral response of Bose polaron, a many-body system consisting of an impurity immersed in a bath of bosonic atoms. We find that the Efimov correlation can be greatly enhanced by increasing the mass ratio between the bosons and the impurity, which results in visible signatures in the rf spectrum of the polaron. Using a diagrammatic approach up to the third-order virial expansion, we show how the mass imbalance and the enhanced three-body effect modify the line shape and the width of the polaron spectrum. Moreover, we study the effect of a finite boson-boson interaction to the spectrum. Taking the realistic system of Li impurities immersed in Cs bosons with a positive Cs-Cs scattering length, we find a visible Efimov branch, which is associated with the second lowest Efimov trimer, in the polaron spectrum. In particular, by adjusting the boson density the Efimov branch can greatly hybridize with the attractive polaron branch leading to the spectrum broadening near their avoided level crossing. Our results can be directly probed in the cold atoms experiments of Li-Cs and Li-Rb Bose polarons.


Authors analyses the possible directions of preventive and psychocorrectional work with teen-agers, using the psycho-active drugs, in particular, alcohol and drug, at example many facts. This activity must to have the complex disposition.


Presented are two cases that show a diffuse liver uptake on bone scintigraphy using Tc-99m HMDP following an intravenous injections of iron colloid solution. Although the true mechanism of this phenomenon is unknown, it seems that a Tc-99m iron colloid complex was formed and taken up in Kupffer cells of liver


A long history of analysis has taken apart organisms into molecular structures. However, the understanding of how biological forms are put together in development and evolution has eluded biologists until very recently. Comparative molecular data on genes in different phyla is uncovering an extraordinary conservation since Precambrian times of gene structures associated with functions. The implications of these findings and our increasing knowledge of how genes control development in a few model organisms, invites a consideration of possible approaches to tackle the problem of how organismic forms are constructed and evolve.


An informed electorate is vital for a well-functioning democracy. Yet many citizens intentionally avoid the news because it evokes negative feelings of disempowerment and distrust. This study (n = 270) investigated how social media exposure to a new journalistic approach, constructive journalism, influences news consumers. The results showed that constructive social media posts, as compared to negative posts, led to higher levels of positive affect, self-efficacy, and perceived news credibility. In line with the broaden-and-build theory of positive emotions, the effects on self-efficacy and news credibility were mediated by positive affect. A similar mediating role was found for negative affect, counter to the theoretical expectations. These findings shed new light on the broaden-and-build theory, suggesting parts of it generalize to the context of news exposure on social media. The findings also suggest that constructive journalism may be an effective way to mitigate some of the main drivers of news avoidance in the 21st century.


In this paper,for the unsteady thermal conduction differential equation with the third boundary condition,the finite-difference method is modelled and formulated to monitor the rotor thermal-stress online.The Equivalent Strain method is used,the multi-axial stress state model is simplified,and the multi-axial low cycle fatigue is translated into uniaxial fatigue model,based linear cumulative damage model,the rain-flow method is adopted to analyse and calculate the rotor low cycle fatigue damage.


Technical lignins, which are the coproducts of the pulping industry, have a high potential for use in surface sizing of paperboard. We investigated the use of kraft lignin and lignosulfonate in surface sizing of paperboard with the target of understanding the influence of lignins on the development of strength and hydrophobicity. Prior to surface sizing, the lignins are purified by ultrafiltration and precipitation respectively. Strength properties and hydrophobicity of lignin-sized paperboard were measured and compared with references as well as with unsized paper. An increase in the strength properties of lignin-sized samples was observed, which was in the same range as references and at least 10% higher compared to unsized paperboard. Moreover, air permeability, hydrophobicity, and water absorptiveness were affected, and depending on the lignin art, an improvement was achieved. These results encourage partial or total substitution of conventional surface-sizing chemicals by technical lignins.


ABSTRACT Background: Street football can be understood as the most natural way to learn football and it can be a great starting point to develop perceptual, decisional, tactical and motor skills. Importantly, players involved in Street football may develop a strong emotional bond to the game through their experiences playing in an informal setting and eventually this could support their participation in a more structured playing environment. However, nowadays, talented children have reduced opportunities to play the game in this informal environment and instead, are mostly experiencing the game through their participation in organised settings such as in youth football clubs and academies. Importantly, such structured and formal environments afford the children a more rigid and less representative learning environment, which could potentially inhibit the development of creativity and adaptability among these young players. Purpose: The current paper aims to discuss the importance of Street football to players' development and the role of a Nonlinear Pedagogy (NLP) framework to support the design of a player-centred and game-based approach that can contribute to enhance learning of creative and adaptive behaviours in football. Discussion: Pedagogical principles of NLP (representative learning design, information-movement couplings, manipulation of constraints, exploratory learning and reducing conscious control of movement) underpinned by concepts from Ecological Dynamics and working through pedagogical channels (instruction, feedback and practice) can facilitate the design of representative training tasks to enhance learning. NLP emphasises a learner-centred approach and highlights the critical role that the practitioner plays as a facilitator in providing learners with meaningful practice that leads to effective transfer of game-play behaviours. Street football affords features that capture some of the above key pedagogical principles and presents a suitable platform to support the acquisition of game-play behaviour that is meaningful for the individual learner. Conclusions: Through a recognition of the current need to design a football learning environments that capture key elements of Street football, we highlight the relevance of NLP as a pedagogical framework to underpin a learner-centred and game-based approach, supporting practitioners with a set of pedagogical principles. Thus, we propose that through this representative learning environment we can enhance learning in football and contribute to the development of intelligent and creative players.


This paper presents finite element co-simulations for DC magnetic field and microwave non-reciprocal performance of ferrite circulators. Permanent magnets provide a DC bias field, but need to be large for a uniform magnetic field distribution inside the ferrite material. Additionally, the ferrite effective permeability is a nonlinear function of magnetic bias. Smaller magnets give a non-uniform bias field distribution, which can be taken into account in the full-wave simulations. To demonstrate the effect of this nonuniform bias, a commercial ferrite material from Skyworks (TT105) is chosen for a circulator design around 3.9 GHz assuming first a uniform DC magnetic field that saturates the ferrite. A small commercial rare-earth permanent magnet is then simulated to obtain the nonuniform static magnetic field in the ferrite, and resulting HFSS simulations show that the effects of nonuniform bias field on circulator performance can be predicted using a combination of analysis methods.


Based on field survey,information collection and experts consultation,the quantitative grading index system and assessment standards for preference conservation of rare and endangered bamboo in Yunnan Province were established,by using the methods and principles of systematical analysis.The quantitative grading index system included endangered coefficient,genetic coefficient,and useful value coefficient.In addition,7 indicators used to evaluate endangered grading and conservation priorities sequence,were also included in 3 subsystems respectively.Furthermore,the weights of 3 subsystem and 10 indicators were given through experts consultation and analytic hierarchy process.The results showed that the number of the first class species was 14,such as Cephalostachyum scandens,Dendrocalamus sinicus,the second class species 55,the third class species 86,most of them are small graceful palm,such as Fargesia,Yushania,Chimonocalamus.Finally,the problems of conservation priorities sequence is discussed to give some suggestions to protect the rare and endangered bamboo in Yunnan Province.


A48-year-old woman presented with 1-year history of heartburn, regurgitation, and triphasic Raynaud phenomenon (RP) affecting both fingers and toes. She reported paresthesias and pain during RP episodes but did not develop digital ulcers. A few months after RP onset, she noticed the appearance hyperpigmented lesions affecting her fingernails. Physical examination revealed beaked nose, mild perioral furrowing, and sclerodactyly distal to the metacarpophalangeal joints. Fingernails showed pigmented longitudinal bands along their entire length compatible with longitudinal melanonychia (LM) (Fig. 1). The color varied from brownish to black. Hemogram and blood chemistry were within normal values, and immunological studies detected antinuclear antibodies 1/640 with positive anticentromere. Manometry study showed esophageal dysmotility, but no other visceral involvement was found. A diagnosis of cutaneous limited systemic sclerosis (SS) was made. The biopsy of a fingernail lesion revealed hyperpigmentation of the nail matrix and plate without increase in melanocytes (Fig. 2). Longitudinal melanonychia, also called melanonychia striata, is defined as a longitudinal hyperpigmented band that extends from the matrix to the distal portion of the nail plate caused by melanin deposition. Longitudinal melanonychia may occur by


The paper studies how political competition among self-interested parties affects welfare and power allocation between government levels. We find that the unitary and the federal systems of government are not welfare-maximizing, leading to a higher and a lower than optimal centralization level, respectively. Second best is achieved under the system which induces larger potential welfare losses in response to similar deviations from the first best: the risk of large losses force parties to stay closer to the optimum in order to keep the likelihood of winning the elections high. The federal system yields to the second-best solution when inter-jurisdictional spillovers are weak; vice versa a unitary system is better when such spillovers are strong.


The running speed of traditional auxiliary pattern design system which can extract association rules from silk relics database with Apriori algorithm is very low. In this paper, a rare common frequent pattern growth (RCFP-growth) algorithm is proposed to extract the association rules from silk relics database which has the obvious characteristics of imbalance, big data and specific mining target by the user in the auxiliary pattern design system. It contributes to the obvious reduction of the memory and time costs for association rules mining in the system compared to the Apriori algorithm and frequent pattern growth (FP-growth) algorithm. Some pattern designs with RCFP-growth algorithm are shown.


The paper presents an efficient technique for evaluating the DC sensitivity of GaAs monopolar or bipolar devices through a two-carrier drift-diffusion model. The sensitivity analysis is based on the Branin's method for the sensitivity analysis of electrical networks. Numerical results are presented concerning two topics: the behaviour of the distributed sensitivity within MESFET devices and the sensitivity-based statistical MESFET analysis with respect to random variations of the technological parameters, which is the basis of yield-driven device optimization.


On the basis of the field theory at finite temperature, the temperature dependences of effective masses of π and σ meson at the nucleon level are discussed. The character change of nucleon-nucleon interaction at low temperature T(T≤200MeV) are also investigated. The temperature dependences of effective masses of π and σ meson are in good agreement with the results obtained from the Nambu-Jona-Lasinio model at the quark level.


Porous silicon nanowires (NWs) with homogenous lateral dimensions of 90 nm are investigated by Raman scattering experiments along isothermal pressure cycles in a diamond anvil cell. Experiments were performed at variable temperatures up to 400 °C for maximal pressures of about 30 GPa comparing directly with transformations in bulk Si and porous NWs. Scanning electron microscopy demonstrates the persistence of one-dimensional morphology after high pressure investigation. The diamond phase in porous nanowires persists upon compression up to around 20 GPa at room temperature (25 °C) and to about 14 GPa at 200 °C and 400 °C. However, the β−Sn high pressure phase is seen to coexist with the diamond phase above 12 GPa at 25 °C and above 6 GPa at 200 °C and 400 °C. The coexistence region of the two phases is found to be considerably enlarged as compared with crystal silicon at each temperature. Upon decompression from 30 GPa, nucleation to the β−Sn, followed by formation of amorphous structures, is observed for porous NWs. Returning to ambient pressure and temperature, amorphous silicon is the dominant form with a residual contribution of β−Sn. At higher temperatures, nucleation back to the diamond structure is triggered although coexistence of amorphous and crystalline phases is observed up to 400 °C.


Organometallic halide-based perovskite solar cells have played a significant role in the development of photovoltaic technology. The synthesis of the perovskite usually needs specific atmospheres, especially controlled humidity. Here, we demonstrate the synthesis of compact methylammonium lead iodide perovskite (MAPbI3) on TiO2 under ambient conditions through one and two-step spin-coating deposition methods, which both resulted in an unconverted PbI2 on the films. The two-step method provided a higher amount of PbI2 regarding the reaction of methyl ammonium iodide (MAI) with an outer layer of the first bonded PbI2 hindered the inner layer to interact with MAI. The Ostwald ripening (OR) process that was applied to the thin film resulted through one-step deposition synthesis has successfully converted the unformed PbI2 to MAPbI3 with a more uniform, lower void, and higher crystal size as confirmed by XRD and SEM analysis results. The application of MAPbI3 prepared using OR treatment in the solar cell resulted in higher efficiency (7.64%) than the one synthesized without OR (4.91%).


Objective: To describe pharmacological preference for the treatment of neurobehavioural sequela of traumatic brain injury (TBI). Design: Survey. Participants: TBI physiatrists were divided into specialists (completed a TBI fellowship or commit >70% of clinical practice time to TBI) and non-specialists. Outcome measures: Participants were asked to list the drugs most frequently prescribed for each of 15 neurobehavioural symptoms commonly encountered during TBI rehabilitation and enumerate neurobehavioural symptom for which they prescribed each listed drug or drug class. Results: There was no clear consensus on drug of choice for each target symptom. There were differences in drug choice patterns between specialists and non-specialists, especially for agitation. Conclusion: There is limited uniformity in drug selection for various TBI neurobehavioural sequela. Potential explanations include the availability of various medications with similar clinical effect, the variability of clinical presentation and severity of neurobehavioural symptoms and the lack of clinical practice guidelines.


Objectives To analyze the results of HIV sentinel surveillance among Chengdu female sex workers(FSWs) in 2011,and to explore the risk factors for effective preventive measures.Methods Questionnaires,accompany with HIV and syphilis test,were applied to collect demography and behavior information,though which to comprehend the infected situation and to analyze the risk factors with the single χ2 test.Results Totally 801 FSWs were surveyed,with the HIV incidence of 0.12% and syphilis incidence of 3.12%.The awareness rate of HIV related knowledge was 89.26%.The condom usage rate in the latest intercourse was 80.52%,while the consistently usage rate was 53.18% though the last month.Conclusion The HIV infectious rate is relatively low among FSWs in Chengdu;nevertheless,the condom consistent usage rate is to be elevated.


On December 12, 2019, a new Severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) appeared in Wuhan, China, causing an outbreak of coronavirus disease 2019 (COVID-19). On January 25, 2021, the number of COVID-19 deaths worldwide reached 2 million and the number of COVID-19 confirmed cases reached more than 100 million, according to the COVID-Case Tracker by Johns Hopkins University. The pandemic of COVID-19 has a profound effect on human health and has caused sudden changes in human lifestyle through social distance and quarantine at home, with social and economic consequences. Optimizing public health during this pandemic requires not only knowledge of medical and biological sciences, but also all sciences related to lifestyle, social and behavioral studies, including eating habits and lifestyle. One of the methods that can be very important to strengthen the immune system against various diseases such as coronavirus is to modify nutrition and follow the correct diet pattern. The following article is a brief overview of the relationship between nutrition and the coronavirus, as well as key tips for increasing nutritional health at this time in the corona pandemic.


The fall in UK living standards which is following the recession has been widely acknowledged but the question of how this is impacting on different groups within society remains profoundly contentious. Robert Joyce offers an analysis of these changes and argues that we are seeing significant real decline across the income distribution.


Tests were performed to compare the accuracy of two computer system monitors. Specifically, results from a hardware monitor were compared with results from a software monitor. Some of the subreports produced by the software monitor were quite accurate; other subreports were not quite so accurate, but they were consistent from run to run. In view of these test results, it appears that the software monitor can be used to measure the effects of changes made in a system tuning project.


[ spaCy+ImageAI+Spin Glass Theory+Z3 API ] all in Python Language – An Insight into the World of Natural Language Processing(NLP) towards Understanding Informatics of Finite Automata involving DNA Sequencing & Some Interesting Applications like Gene Chips. [ Exploring – NLP+Spin Glass Theory+AI+Theorem Proving in the Context of Developing Next Generation Bio-informatics ]


Increased Metallothionein (MT) synthesis is associated with increased capacity for binding metals such as copper, zinc and cadmium, as well as protection against metal toxicity. A study was carried out using quantitative real-time reverse- transcriptase polymerase chain reaction (q-RT-PCR) in freshwater teleost, Channa punctata (Bloch), after exposure to sub-lethal concentrations of cadmium. Post 14 days exposure, the heightened MT mRNA expression was seen only in kidney, whereas in contaminated liver and gills, the MT gene expression collapsed significantly below the basal level. The difference in the effect of various concentrations of cadmium on MT mRNA transcript level in the tissues under study was found significant. The study indicates that the expression of MT mRNA in C. punctata occurs in tissue specific and dose dependent manner.


Pearl millet or Bajra (Pennisettum typhoides) are widely grown in Africa, Asia, China, and the Russian Federation and can be used as either grain or forage. Pearl millet is a highly drought-tolerant cereal crop and an important food grain.it is generally grown as a rainfed crop on marginal land with few inputs and little management. It is grown as a food crop in tropical Africa and India, with most of the production concentrated in Sahelian West Africa and north western India. These regions are characterized by high temperature, short growing season, frequent drought and sandy infertile soils. India is also considered to be the secondary center of origin for pearl millet, with many distinct cultivars growing throughout the country. In arid regions of India, pearl millet is a major source of food. These grasses produce small seeded grains and are often cultivated as cereals (Carl E pray and Latha, 2009). It is grown mostly in Rajasthan, Uttar Pradesh, Gujarat and Haryana, Madhya Pradesh Maharashtra, and Karnataka are the major Bajra producing states. (Directorate of Economics & Statistics, DAC&FW, 2014-15). In Karnataka It"s cultivated an area of 0.234million hectares (M ha) with production of 0.248 million tons (M t) and an average productivity1117 kg/ha. It"s mainly cultivated in north eastern part of Karnataka namely International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 7 Number 12 (2018) Journal homepage: http://www.ijcmas.com


Most of the women are mother over her life, and for it they must pass necessarily through the childbirth process, where most of them suffer tears or episiotomies (perineal trauma). The aim of this review is to determine if the perineal massage is a beneficial method to prevent the appearance of perineal trauma in the childbirth. For this purpose, a bibliographical search has been realized in Pubmed, Cocrhane Plus, Cuiden Plus, ENFISPO, IME, CINAHL, PEDro and Google Académico databases. There have been selected a total of 15 articles, which after being checked they show the possible benefits of the perineal massage. In them it is observed


A resonance phenomenon in the zeroth diffraction order of a gold-wire grating is explained by the excitation of surface polaritons. This effect is connected with a strong enhancement of the electromagnetic fields on the wire surface and consequently with a peak of power losses in the grating material. Measurements of the zeroth-order transmittance have been performed on gold gratings with periods of 1 and 2 micrometers in the near-infrared region which are in agreement with theoretical results. Furthermore, dispersion relations of the first-order coupling mode are presented having large energy gaps in the center of the Brillouin zone. It is shown that this energy gap strongly depends on the wire profile. In this coupling branch, however, practically no dispersion could be observed for optical wavelengths less than the grating period.


The present invention with the upper surface portion and the substrate when the substrate portions which are opposed to each other; An anode electrode formed on a lower side of the upper surface portion and the substrate; Brightness of the entire layer is formed on the lower side of the anode electrode, it generates an electron hole pair by the X-ray and; When the cathode electrode is formed on the upper side of the unit substrate; The emitter and which is formed on the upper surface of the cathode of the cathode emitting electrons; A gate electrode on the upper side of the cathode electrode is formed on the upper side of the insulating layer to be stacked and surrounding the emitter and; Receiving an e-hole pairs generated by the X-rays from the anode to the data processing section for processing a digital data information by the signal processing of filtering, amplifying, storing, etc. A / D conversion; Using F Idi (FED) device, it characterized in that the configuration related to the x-ray detection substrate. According to the present invention, to obtain high-resolution images of, and also a large area from, angry, and the detection efficiency of the new system of high-performance digital X- ray image of an electric signal, while facilitating the production and manufacturing process compared to the conventional method It has the advantage that the detector is provided. FED, Spindt-Tip, a carbon nanotube, a planar emitter, the conductive fine particles, the photoconductor layer


New chiral monoaza-15-crown-5 derivatives and lariat ethers anellated to phenyl β-D-glucoside have been synthesized which show significant asymmetric induction as phase transfer catalysts in the Michael addition of 2-nitropropane to chalcone (84% ee) and in the Darzens condensation of phenacyl chloride with benzaldehyde (74% ee).


Essay delivered in the National Seminar on Anthropological Researches in India: Retrospect and Prospect held at Guwahati, Assam in November 2011. (Edited by Gautam Kumar Bera and K Jose SVD.)


This paper investigates whether there is a wage penalty that negatively affects foreign-born employees in the United States and Canada, addressing the following two questions: (1) Does being a foreign-born employee result in a wage penalty in the United States and Canada? And if so, (2) How does this penalty differ across the two countries over time? With data collected from the Integrated Public Use Microdata Series (IPUMs), four separate multiple linear regression models are estimated to compare the presence of wage penalties across various industries and occupations. These analyses cover the following comparisons: the United States in 1990 and 2000, Canada in 1991 and 2001, the United States in 1990 and Canada in 1991, and the United States in 2000 and Canada in 2001. For each comparison, this study finds that individuals who identify as foreign-born to the country they are employed, face a wage penalty. These findings indicate that this specific status (foreign-born) correlates to lower wages compared to the average employee and suggests changes in immigration policy in both countries over time as potential explanations. These results are important for future consideration of wage and salary incomes to individuals in both countries, regardless of foreign and domestic-born status. ACKNOWLEDGEMENTS I would like to thank Professor Pedace and Professor Flynn for their support and willingness to share their knowledge, in aiding me in the process of writing this thesis. Through our discussions, I learned a great amount and was inspired to continue writing about this topic. I would also like to thank my family and friends for listening, sharing, and motivating me to continue moving forward, writing a thesis I have both learned from and am extremely proud of.


To determine the calcium content in the calcium products by the methods of potassium permanganates method,EDTA titration,spectrophotometer.According to the experimenting and result indicated that spectrophotometer is much accurate than other two methods,which was more fit for experimental teaching.


As COVID-19 reached pandemic levels in March 2020, schools shifted to remote learning. Student parents in higher education had to adapt to their own remote learning and assume responsibility for childcare and their children's education. Few studies have explored the impact of COVID-19 on mothers who are also full-time students. This study utilized a phenomenological approach to understand the lived experiences of mothering students during the COVID-19 pandemic. Student mothers were recruited from a large, public, Hispanic-serving university in a Southern state. We conducted interviews with 15 student mothers who had at least one child under the age of 18 during the first six months of the pandemic. Three main themes emerged from the analyses: (1) successfully meeting educational requirements; (2) dealing with the mental health impact of the pandemic; and (3) changing the institutional structure. The first theme captured strategies mothering students implemented to ensure their own or their children's educational goals were met. The second theme encompassed how mothers handled the stress caused by the pandemic. The third theme explored ways that mothers resisted gendered expectations and norms around care. Implications for policy and social work practice include changing institutional structures to enhance support for mothering students.


Abstract. The effect of benzodiazepine anxiolytic diazepam in Danio rerio was investigated. Methods. A stress test on novelty situation was used: a fish was placed first in a beaker with a dissolved pharmacological substance (or water) and then into a novel tank for 6 min, where the trajectory, the path length, the number of movements to the upper part of the novel tank, the number and time of the pattern of "freezing" of the experiment were measured. Results. In response to the novelty of tank, the fish was shown to react by submerging to the bottom, increasing the freezing, and reducing the number of movements to the upper half of the novel tank. After diazepam exposure (administration), the fish was not only in the lower, but also in the upper part of the novel tank. A pharmacological analysis of diazepam effect in Danio rerio showed that in a certain dose range of 1–10 mg/l anxiolytic reduces (in comparison with the control group of fish) the number and time of freezing, increases the number of movements in the upper half of the tank and the swimming time in upper part of the tank. Diazepam causes a disinhibition of motor activity at doses of 1 and 5 mg/l, which may be explained by the effect of small doses of tranquilizers on presynaptic GABA-A autoreceptors. Diazepam 20 mg/l has a depriving effect. Conclusion. Diazepam acts in a higher dose range (1–10 mg/l) than phenazepam (0.1–1 mg/l) in Danio rerio . At the same time, diazepam is characterized by a domed dose-dependent effect, in contrast to the action of phenazepam. The prospect of using Danio rerio as an animal model in behavioral pharmacology is not inferior to studies in rodents.


Bagasse formic acid pulp was produced under the typical condition of 90% (v/v) aqueous formic acid, ratio of liquor to bagasse (L/S) 10:1(v/w), pulping temperature 100℃,and pulping time 80 min. High lignin content on the surface of the pulp fibers was found when the fiber surface chemical composition was analyzed by XPS. The formic acid pulp from bagasse could be bleached to a high brightness over 85% ISO by the short bleaching sequence of EpDQP.


We were disappointed by the paucity of information about children in Whitty and colleagues' review of imported malaria1 since 15-20% of imported malaria occurs in children.2 In the only paragraph on severe or complicated malaria in children the authors quote a paper on endemic childhood malaria in Kenya.

Children with imported malaria …


Objective To explore the efficacy of argon plasma coagulation(APC) in treatment of upper digestive tract disease under endoscope.Methods 61 patients of upper digestive tract disease were treated by APC.Among 61 patients,26 cases were gastroesophageal polypus,13 cases were gastritis verrucosa,8 cases were Barrett′s esophageal,42 cases were upper gastrointestinal hemorrhage.Results For 26 cases of gastroesophageal polyp,the lesions were eliminated and no residual lesions were found when checked by endoscopy 3 months after APC treatment.For 13 case of gastritis verrucosa,all cases recovered thoroughly when checked by endoscopy 1 month after APC treatment.For 8 cases of Barrett′s esophageal treated with APC accompanied by drugs,2 case relapsed as shown by endoscopy and biopsy 1 year after the treatment.For 14 cases of upper gastrointestinal hemorrhage,no hemorrhage was found after APC treatment.Conclusion APC in treatment of upper digestive tract disease under endoscope has features of safety,effective ness,easy operation and less complications.


30 June 2014 AN ERA IN GOVERNMENT PRINTING ENDS After decades of serving Territorians the Government Printing Office is closing its doors today, Shadow Minister for Corporate and Information Services, Kon Vatskalis noted. "Our thoughts are with the workers and families of the dedicated staff of the Government Printing Office," Mr Vatskalis said. "It's a sad day for everyone involved and I hope the Government is treating its GPO staff with respect and the appropriate effort to retrain and redeploy staff. "The GPO has served successive Governments well for more than 30 years, providing all Parliamentary printed matter such as legislation and Hansard as well as providing the secure printing of publications such as Budget papers. "The Government needs to explain to Territorians how it will ensure that printing remains within the Territory. "We deserve every effort to support local industry and local jobs."


The structures of typical organic species in Jincheng No. 15 anthracite (J15A) were characterized by solid-state 13C nuclear magnetic resonance, X-ray photoelectron spectrometry, X-ray diffraction, and Fourier transform infrared spectrometry in combination with gas chromatography/mass spectrometry and electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry analyses of the resulting soluble organic species from ruthenium-ion-catalyzed oxidation (RICO) of J15A. The results show that the typical organic species in J15A are condensed aromatics, along with small amounts of methyl group as the dominant side chain on the condensed aromatic rings (CARs) and methylene linkage connecting the CARs. Every aromatic cluster contains five rings on average, and the substituted degree of each aromatic ring is very low. In addition, J15A is rich in peri-condensed aromatics but poor in cata-condensed aromatics and polyaryls. The oxygen functional groups in J15A include C–O and >C═O groups. Pyrrol...


Background: Acute anal fissure (AAF) heals spontaneously with conservative line of treatment. Chronic anal fissure (CAF) needs either traditional surgical lateral sphicterotomy or chemical sphincterotomy with topical agents. The present study aims at the effectiveness of topical diltiazem (DTZ) cream over topical glyceryl trinitrate (GTN) ointment in the treatment of chronic anal fissure.Methods: A total of 100 patients with CAF were included in this comparative prospective study conducted in Rajarajeswari Medical College and Hospital Bengaluru from July 2017 to December 2018. Eligible patients were randomly assigned to one of the two treatment groups of 50 patients each and were advised to apply 2% DTZ cream or 0.2% GTN ointment by fingertip to the anal verge twice daily for 8 weeks. The results were analysed and compared on two weekly intervals to know the effectiveness of treatment. P value of <0.05 is considered to be significant.Results: Complete healing of the fissure occurred in 80% of the patients in DTZ group against 76% in the GTN group by the end of 6 weeks (p>0.05, statistically not significant). Mild headache was experienced by 14% of the patients in the DTZ group, while 46% of the cases in the GTN group reported about the same (p<0.05 statistically significant).Conclusions: Topical 2% DTZ appeared to be well tolerated and effective preferred first-line method of chemical sphincterotomy with less side effects for chronic anal fissure.


ABSTRACT Self-determination (SD) and game-based learning have attracted great attention, and recent investigation studies have shown that SD is closely related to flow and mastery experience. This study pioneered at developing a game-based learning program with an emphasis on SD intervention, in which comprehensive creativity strategies within a story context were presented. Through this training program, we further differentiated between the ways that the SD need before the training and the SD experience during the training influenced flow and mastery experience pertaining to creativity. The participants were 82 third and fourth graders. The results showed that the SD experience was a better predictor of the pupils' flow and mastery experience than the SD need, suggesting the importance of implementing SD intervention to maximize the game-based creativity learning. The developed training program and the proposed theoretical framework provide valuable implications for the instruction of creativity.


Heat transferring and thermal design of the steel die for low pressure sheet molding compound were analyzed and optimized by MATLAB software.The flexural properties of specimens,molded by normal and thermal deign optimized die respectively,were compared.In addition,the fracture surfaces were carefully analyzed by SEM.Results show that LPMC and traditional SMC differ in the heat transferring property.In the molding process,there occur phase transition by the decalescence of crystalline polyester.When the distribution of the heating pipes in the steel die was optimized,the surface temperature of the steel die was much even during the curing of LPMC,and the difference in temperature was limited in 3 ℃.The flexural strength of the specimens,cut from the center and the corner of the parts molded by thermal optimized die,was almost the same.They could reach about 170 MPa.


The author of the article makes an attempt to understand the process & the meaning of supervising of the future specialists. The article defines & analyses conditions of the process: the usage of the interactive teaching methods, creation of the comfortable learning environment, development of the personality which can be realized independently. The stages of the professional development of the future specialist are given & shown here: the adaptation stage (the first year), the intensification stage (the second & the third year) & the identification stage (the fourth year); the author characterizes the difficulties & special features of the adaptation process of the first-year student, i.e. relations with the group-mates & teachers, new requirements of learning, planning of the learning process & individual work, adaptation to the new living conditions & social environment. The psychological work technology of the adaptation stage is given here. Some results of the monitoring of the students at this stage are shown in the article.


Summary:MDM2 was transfected to acute lymphoblastic leukemia(ALL) line EU-4 cell which lacks P53 expression and expresses very low levels of MDM2.The results showed that MDM2 upregulated P65 expression in mRNA level and protein level.The effect of adriamycin (ADM) on MDM2-transfected EU-4 cell was detected by MTT assay.It was found that MDM2 transfection could increase drug resistance of EU-4 cells to ADM as compared with parent cells.Since the expresion of E-selectin is P65 dependent,E-selectin promoter-CAT construct and P65 and MDM2 expression plasmids were cotransfected to EU-4 cells.revealing that MDM2 increased P65-mediated transactivaton of E-selectin promoter.In the absence of P65,MDM2 had no effect on the transactivation of E-selection.Moreover,MDM2 antisense couldn't change the transactivation of E-selection.It was concluded that MDM2 could up-regulate transcriptionally P65 expression;MDM2 increased drug resistance of leukemia cells to ADM;MDM2 elevated NF-kappaB activity in P53-independent manner.


Digital learning media are needed by educators to create meaningful learning. So, it needs a lot of creative, effective, and educational innovations. This study aims to describe the state of mathematics learning media in elementary schools and to analyze the need for developing interactive multimedia learning based on a guided inquiry on geometry material for fifth-grade elementary schools in Surakarta. The method in this research is qualitative and quantitative research designs. The data collection technique used a purposive sampling technique. The sample taken consisted of 116 students and 4 teachers. Interviews, observations, and document analysis were used for qualitative data collection, while quantitative data were carried out using questionnaires. An interactive analysis is used to describe the data that has been collected. From the data obtained, it can be seen that the teacher sometimes does not have time to prepare learning media. Students and teachers never use interactive mathematics learning multimedia. There are some misconceptions in geometry material so that students are unable to solve problems. Teachers and students need interactive and educational learning media. From the facts and needs of instructional media, it is necessary to develop interactive multimedia learning based on guided inquiry to improve students' problem-solving abilities in geometry material.


SUMMARY Autism spectrum disorders (ASD) have demonstrated an increase in prevalence and are no longer considered a rare condition. The Autism Diagnostic Interview-Revised (ADI-R) and the Autism Diagnostic Observation Schedule-Generic (ADOS-G) have been gold standard instruments to diagnose ASD, but neither of these tools identifies associated comorbidity. The new Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Present and Life time version KSADS-PL-2009 version added a supplement for assessing ASD.


Local governments are exploring various carbon reduction strategies to achieve low or even zero carbon urban development that offer a higher quality of living than typical 'business-as-usual' development approaches. Municipalities are also concerned with building capacity to withstand changing climate by increasing the physical resilience of urban infrastructures (McDaniels et al. 2007). Redesigning low-carbon city centres with distributed infrastructure networks is gaining increasing interest, as well as improving resource flows that foster community resilience and improved energy, water and waste services (Biggs, Ryan et al. 2007; Ren and Gao 2010).


This taxonomic revision of the recently reconstituted genus Orthocarpus is based on herbarium and field studies, evidence from floral morphology, SEM studies of seed and seed-coat morphology, chromosome numbers, habitat, and geographical distribution. Nine species and five subspecies are recognized. Keys to species and subspecies and a complete synonymy of taxa are provided. Each species and subspecies is illustrated with line drawings showing habit and floral morphology; distribution maps indicate sites of known populations for each taxon. One new sub- species, Orthocarpus tolmiei subsp. holmgreniorum, is described and two new combinations, Orthocarpus cuspidatus subsp. copelandii and subsp. cryptanthus, are proposed. It has been more than 60 years since Keck's 1927 revision of Orthocarpus Nutt., a discerning and useful treatment that was prepared chiefly on the basis of field observation and the her- barium specimens then available. Although Keck's treatment has served admirably, there is now a need for updating his work by reassess- ing intergeneric and infrageneric relationships, and providing a new and comprehensive tax- onomic revision.


The pre-salt region is very hostile to the materials used in such environment due to some factors found under the pre-salt layer such as: corrosive gases, oil formation water, high pressures and so on. In order to evaluate only the effect of the oil field formation water on the corrosion resistance of austenitic stainless steels in such environment, two austenitic and two superaustenitic stainless steels were tested in synthetic oil field formation water using the electrochemical technique called step potential. In this technique, potential values (vs Ag/AgCl ) is applied in steps of 50 mV every 1 h until a current of 1 mA was achieved. The results showed that the common austenitic stainless steels are not suitable for the use in chloride-containing environment as the one found in the pre-salt region. They exhibited pitting corrosion. The superaustenitic stainless steels tested exhibited a good corrosion resistance in this medium and can be a solution for the use under some pre-salt conditions.


This paper investigates active cancellation techniques for a Full-Duplex transceiver. An auxiliary transmit chain is employed to create the cancellation signal, which is then injected at the receiver RF front-end by using a microstrip cou-pler. Two methods are proposed to calculate the self-interference cancellation signal. While the first method assumes the transmit chain to be strictly linear, the second one additionally incorporates nonlinear effects, occurring especially in the RF power amplifier. The linear method reports experimentally around 48 dB of self-interference suppression under linear system behavior. Experimental results show also 50 dB of suppression by using the nonlinear method and under nonlinear system behavior, whereas the linear one reports 47 dB of suppression under the same conditions.


With exponential increases of information flows on social media platforms, user experiences have become fragmented, cacophonous, and often overwhelming. Such "noise" makes learning on these platforms difficult. By contrast, the principle of polyphony frames learning with social media as a graceful, intentional threading together of multiple voices. In this paper we describe AmpDamp, a design concept for orchestrating polyphony in social media environments. Connecting a physical knob to a browser extension, AmpDamp translates the gestures of turning up (amplifying) and turning down (dampening) into a dynamic orchestration of the "volume" of a user's social media feed. By focusing on issues of granularity and temporality, we position polyphony as an entry point into incorporating the values of control and curation into learning experiences using social media.


Noises in a node usually cause uncertain data in Multi-Sensor Networks(MSN).People want the best social benefit under such circumstances and with limit band-width,but the node agents are selfish and rational,and always want to max-imize their gains,so the trust is a very important factor.Thus,the Certain Trust(CT) model is applied on MSN.The sensor can pay fewer premiums for a better POS(Possibility of Success) to complete the task,and maximize their gains from a market and obtain the best social benefit at the same time.It is simulated by java program and good performance is achieved to prove the superiority of this scheme.


Objective To probe the nephron spring surgery for renal neoplasms.Methods Form April 1995 to October 2001,nephron sparing surgery was done for 18 cases of renal tumor,of which there were 3 with carcinoma and 15 with benign neoplasms.Among them,1 case was sole kidney;and 17 cases were a unilateral renal neoplasm and a normal opposite kidney.The diameter of the tumor ranged from 1 cm to 8 cm,with a mean of 3.5 cm.17 patients underwent partial nephrectomy and 1 tumor nucleation.Result All patients have been followed up for 2 to 72 months with a mean of 32 months,no surgical complication or local tumor recurrence has been found.Conclusion Nephron sparing surgery is safe and effective for the treatment of renal neoplasms.


The influence of silica source(silica sol and silica gel) on the crystallization process of mordenite zeolite was investigated.It was found that the products of the crystallization were totally different with silica sol or silica gel as silica source,even if the other conditions were the same.By using a synthesis mixture of n(Na2O)/n(SiO2)=0.2,n(SiO2)/n(Al2O3)=30,n(H2O)/n(SiO2)=26 and after crystallization of 24-72 h at 180℃,mordenite zeolite could be synthesized with silica gel as silica source,whereas a solid product was obtained with silica sol as silica source.A series of experiments were designed to explore the reason why the products were different using different silica source.It was proved that the n(SiO2)/n(Al2O3) ratio in the gel was the determining factor for mordenite crystallization instead of the apparent n(SiO2)/n(Al2O3) ratio in the mixture.The use of different silica source led to the different n(SiO2)/n(Al2O3) ratio in the gel though the apparent n(SiO2)/n(Al2O3) ratio was the same.


Alteration products of basalts from the four holes drilled during Leg 81 were studied and found to be characterized by the widespread occurrence of trioctahedral clay minerals (Mg smectite to chlorite). In some cases zeolites (analcite, chabazite) are associated with the saponite. A more oxidizing stage is marked by a saponite-celadonite association, presenting the geochemical characteristics of hydrothermal processes. Later stages of alteration are represented by palagonitization and subaerial weathering at two sites. These different alteration processes of basalts from Leg 81 record the paleoenvironment during the first opening stages of the Northeast Atlantic Ocean in the Paleocene-Eocene periods.


Abstract Pediatric tuberculosis is a health problem of special significance because it is a marker for current transmission of tuberculosis in society. The research aimed at analyzing the peculiarities of detection and course of pediatric extrapulmonary tuberculosis (EPTB) taking into account the profile of drug resistance. A retrospective study of medical charts of children with EPTB (n = 47; 1st group) and pulmonary tuberculosis (PTB) (n = 49; 2nd group) aged 0-15 for 2013-2020 has been conducted. 2 subgroups with EPTB were identified separately: resistant (EPRTB) (n = 23) and sensitive (EPSTB) (n = 24). Results and discussion. The frequency of EPTB was 9.8%. Tuberculosis of peripheral LN (40.5%), CNS (27.7%), bones and joints (23.4%) was significantly more often diagnosed, than other lesions. Almost half of children with EPTB had a miliary distribution. In 44.7% of children with EPTB contact with a patient with tuberculosis was not established. EPRTB was significantly more common among children under 1 and up to 3 years of age than EPSTB. The resistance to combination of HR (73.6%) was found more often than to HRES (10.5%), HRS, H and Z (5.3% each; p<0.01). In 73.9% of children with EPRTB was detected when seeking medical care, in 13.0% the time to diagnosing lasted 6 months. Among children with EPRTB, gradual course was more frequent and in 47.8% intoxication syndrome was dominating. 78.3% of children with EPRTB were not vaccinated. Conclusion. The above indicates the need to intensify preventive measures against tuberculosis among children, especially at risk groups, make monitoring of contacts and their treatment.


A theory of "growing" electric space-charge waves in drifting, interpenetrating electron streams, or mixed ion and electron streams, has been developed by Pierce, Haeff, and others to explain the operation of the electron-wave tube and other amplifying devices and perhaps also the origin of some solar radio emission.


: By integrating literature from flood hazard research and urban economics a theoretical structure is developed to explain changes in residential land values following flood events. The negative aspects of the flood hazard are shown to be capitalized in the value of the property. It is further suggested that land values (i.e., capitalization) will vary both spatially across the floodplain and temporally depending on the frequency, severity and spatial characteristics of the flood event. Previous work in this area has not addressed the capitalization process explicitly and has not specifically examined the ability of the land market to recover. This may account for the contradictory findings in the published literature.


A laboratory screening method using an autoclave digester has been developed for the evaluation of surfactants in kraft hardwood pulping. The effects of surfactants on cooking liquor penetration and diffusion have been explored. The use of surfactants results in a more uniform cook with lower Kappa number, lower screen rejects, lower pulp resin content, and improved black liquor residual active alkali content. The laboratory results correlate very well with mill experience in screening additives for digester additive programs. Research shows that raising the Kappa number with the surfactant at the digester discharge can boost pulp yield. Kraft-surfactant pulping appears to be an appropriate technology in resolving screen rejects in combination with retrofitting oxygen delignification.


The ignition characteristics of a plasma torch for a hydrogen jet injected parallel to a subsonic aire ow were experimentally studied. Theregion of the injector position whereignition occurred became gradually narrow with an increase in the distance between the fuel injector and the plasma torch and steeply narrow with an increase in the aire ow velocity. This suggests that the ignition limit strongly depends on the penetration height of the plasma torch, which is in inverse proportion to aire ow velocity. Nitrogen and oxygen were compared as feed stocks. Results obtained showed no difference in the behavior of the plasma jet itself, the ignition limit, and the e ame shape. Calculations of ignition delay time for an H 2/air mixture with the addition of N and O radicals showed the sameeffectivenessand werefoundto besuperiorto theHandtheOHradicals.However,thedegreeofdeterioration of an anode nozzle made of copper was more severe for oxygen plasma than for nitrogen.


We fabricate a SiOC comb structure capacitor device, and apply mechanical stress into samples by bending. From I-V fitting, we obtain the energy barrier lowering β, and conclude that the electron transport in single damascene capacitor is due to Poole-Frenkel emission. Tension yields a decrease of energy barrier in the single damascene dielectric layer and an increase of leakage current compared to the unstressed sample. In contrast, compression stress yields the energy barrier increase and the leakage current decrease. The variation of leakage current is originated from the energy barrier change induced by mechanical stress.


The emission spectra from welded and un-welded (normal) porcine aorta tissues were measured on both sides of intima and adventitia layers. A tunable Forsterite laser and a Cr4+: YAG laser with wavelengths of 1250nm, 1455nm and 1460nm were used to weld porcine aorta tissues. Three emission bands emitted from three key fluorophores were studied under different welding and excitation conditions. With excitation wavelength of 340nm, the 395nm band is associated with the emission from the structural proteins of collagen type III and type I. The 445nm band obtained is associated with the emission of the structural protein of elastin. The 350nm band recorded with excitation wavelength of 300nm is associated with the amino acid of tryptophan. The relative emission intensities of collagen, elastin and tryptophan at their fluorescence peaks changes with laser tissue welding wavelengths indicate the change of contents of those tissue molecules. The ratio of emission peak intensities of collagen to elastin with welding laser wavelength of 1250nm increases by 0.13 as compared to the normal aorta tissue at the intimal side. For the adventitial side of aorta tissue, this ratio decreases by 0.38 in comparison with the normal tissue. These results indicate that content of collagen changes relative to elastin due to laser tissue welding. The peak fluorescence intensity of tryptophan for both sides of welded tunica intima and adventitia increases significantly in comparison with the normal tissue when the optimum laser welding wavelength of 1455 nm was used.


The determination of the component of Universal
Grammar where word formation takes place has been a
major area of controversy in the literature. The
main goal of this book is to
uncover the component of Universal Grammar where a
morphologically-complex de-adjectival verb is
formed. It shows that although the internal
structure of morphologically-complex de-adjectival
causatives is empirically and theoretically
predicted to be opaque to phrase-level operations
(Borer 1991; Li 2005), syntactic processes and
descriptions are not oblivious to the internal
structure of that derived structure in Oromo and
Amharic. Building on a well-motivated assumption
that there is no well-formed syntactic structure
into which a synthetic de-adjectival verb might
project (Li 2005), we advance an argument to the
effect that both members of those derived de-
adjectival causatives are lexically independent.
Inspired by work done in Distributed Morphology
(Halle & Marantz 1993), we maintain that a merger of
the members of de-adjectival causatives takes place
post-syntactically in an intermediate level of
representation called morphological structure (MS).


This document provides supplementary information to "Video-rate, mid- infrared hyperspectral upconversion imaging," https://doi.org/10.1364/OPTICA.6.000702 . This document describes several aspects of hyperspectral upconversion imaging which are not addressed in detail in the main manuscript such as, the point spread function, tangential phase-matching, quantum efficiency and the signal to noise ratio in upconversion imaging. In addition, the distortion in the image caused by the crystal rotation is addressed. The effect of using a spinning diffuser to remove the speckles is demonstrated. The details of the biopsy samples and the FTIR acquisition are presented.


may be fairly called local hypertrophies-of tissue, no 'well defined line of demar ation can bedrawin. 'Some of the ehronic mammary'of glandular tumours illustrfate this. 'But, even it' such outgioWtha the lirst departure from norlnal type' is siown, not'only in the formntion of their substance, bit also' in the 'fact that they are not in such' close physiological relation Oith normal Structures as these are w'ith each other.. The sympathy' which universally prevails between {he seve, ial structures and organs df the, body, and which is mafitiined either through the blood of by the nervous system, or in both ways, vaties in degree iamong natural structures; but between all, these anid tumours, a farl'wider divergence is found. They rise and fall -less with the ebb and flow of general life, and they are less affected by 4lhanges' in other; structures. Thus, by the most innoceht and homologous'tum6 irn,' is the first step taken 'towardsAh independenit life; 'asid,' it' 'may` b observed, that 'this independence gradually gains srength, and tbecomes more marked as we pass from "the, most innocent,' through tumourS of varying degr-ees 3f mialignancy, to the. very WC6fst iand, -as' 'we have seen, it is to the comparative independenco of Wtir life, that the most deadly of their attributes belog. And while ttmour-s of the most innocent type touh,and, indeed, ass'into nXtral -strudtures, the most malignant touch, if they do not actually paiginto, the class of parasites:. P}rasites are living forms, having, toiP'idi rarious degrees, a pbower of independent life. For the most part, they can flourish only inthe living body; sand while there, they too are within the pale of the laws of its natural life;b*ut, 'within thiis, they have an individual life, more independent of that of the boAy in which they live than tumours possess and, moreover, they tin, for a longer period, mnaintain life altogether apart from the body t are prone to infest." They can maintain a separate life in some otfits lower grades; but they canexhibit theiriful vital endowments only in the body to which they belong. Now at present it must be confessed, that experimmnts on the grafting or inoculation of tumours, e,ven -the, most malignant, have not been attended by success; we eannot' yet say that cancer can be thus propagated; still there are some curious facts in reference to this. In certain cases, it has been observe-d that, when acancerous mass has been allowed, for some time, to be it:> tontact wvith. eih apparently 'healthy surface, this healthy surfaces 'hs at length become' cancerous ; and, in this manner, cancer seems capable, after thei fashion of a parasite, of passing from part to part. Froi part to part ofthe same body only, but I wonder what 'vould happen if' such an experiment could be fairly tried between different bodies. May not the experiments on inoculation hitherto have failed because of the crudeconditions under which they have beeni performed ? But be this as it mnay, and setting aside this conjecture, it would really appear that the initerval between the worst cancer and certain parasites must be a very narrow one. Through the various kinds of parasites we pasg to altogether independent forms of life; and I can,Aot'help-thinkhig that, from this point of vieW, much interest must be attached to tumours,; as indicating the first steps towairds the assumption of a separate and independent existence. But, u[itil it can be shown that tumours may be transmitted from one persoii to' another by grafting or inoculation, it must be acknowledged that there is 'this sharp line of distinction between all of' the-m. and parasites. Parasites come always from withott,; tumours arise only from within; from some part or natural structure of the body itself. And it may be said that, after all, nothing more is known of the origin of tumours than this. Once started, we may perhaps see something of the laws which regulate their existence, but concerning their origin we are altogether in the dark. Yet, still recognising in this darkness an obscurity which enshrouds also' some of the largest facts in physiology, we may perhaps be able to diseernuthe direction in which light must at length come. While tumours, then, appear to be bounded by the lower and simpler forms of parasites on the one hand, they are approached by what are regarded as abnormal conditions of nutrition on the other. The process of nutrition in its simplest state is one of mere maintenance. The bulk and weight of a structure or organ is preserved, in spite of constant wear and tear. In growth, there is increase either of bulk or of weight, or of both. But why, at a particularpoint, growth should cease, we do not know. We can only speak of it as a natural law. It' is the same with regeneration oir repair after injury. There is reproduction up to a certain point, and then this, like normal growth, closes. But, within limits, the growth or natural increase of a structure or 'organ is regulated by the :conditions under which it exists. Some of these !conditions are healthy ones, others are morbid; and thus we speak of-overgrowths or hypertrophies as conservative or pathological. .Now, the hyp&rtrophies which are morbid in their nature seem to lead us on to tumouts. The morbid hypertrophies, as a rule, affect, more or less, the wtble bulk of an organ, as in the instance of the prostate or the thyroid gland. But'the more dr'lrkispvery' tt ant fact ior n,-for sometimes the 6drgioWth'ifl6i ly-I ^otil of the strvettire, leaving -the reSt inchknged.ThiW' fiJabkWdadxty illustrates i'n the tnbrgans j'u§t niefitiouied Only a ;rticIar ,; as a' single' lobe, may become over~tow, And the lnitt'o sidcf;ee,'aion we aan' hardly indicate. iAga'n, the et'cess of sub taridt r bb produced in oits obò6th of two wys itheritb a; Sim-ple enlSxmer t of the: alle,ad'y existing elements of thW oran, or by the dSrlopii nt anew of additional elements. -The organinay becine! larger fi increase in the sizb, or in the nnmber df'its` elemenarystieies Thus, 'e liave ih4t is ealled simple hI petrophy, atd wha is called numerical hypertrdphy or hyperplasiia and' I thiAik' there 'fr be little :doubt 'htlh i'nroase by hyperprdsia'is' at least the moie'conmioh proees§:' I' inh'nhy eSses, this is clearly re*4aled, as in epithelial strtic. tures generally, AMndglands more particularly. Now, surely, the transition from a 'local hyperplasiato a distinct tumour iis not 'S vety abrupt one. Nay, is it not, I repeat, sonletimes 'ver$ diffcult, if not impr'cticable, as in the instance of certain masses in the mammary or prostate gland, to' draw' any' lite of distinction between them? The mystery, then, which enshrotide the' origin of 'tumourS appear` to envelop also other eccentric m6des of litat action which are nevertheless more akin to some of the; nonitmal' processes of life. Before we shall ever be able to answer the question why or howr do tum6itrs form ? it seems to' ie 'that we must b'e able to sol0e thd problern of normal growth 'and development,'and to-answer the question' Why'or how it is that these coitinue up to 'a certain point, and then sadderily cease ?


A mobile version of the NASA/DARPA Robonaut humanoid recently completed initial autonomy trials working directly with humans in cluttered environments. This compact robot combines the upper body of the Robonaut system with a Segway ™ Robotic Mobility Platform yielding a dexterous, maneuverable humanoid ideal for interacting with human co-workers in a range of environments. This system uses stereovision to locate human teammates and tools and a navigation system that uses laser range and vision data to follow humans while avoiding obstacles. Tactile sensors provide information to grasping algorithms for efficient tool exchanges. The autonomous architecture utilizes these pre-programmed skills to form complex behaviors. The initial behavior demonstrates a robust capability to assist a human by acquiring a tool from a remotely located individual and then following the human in a cluttered environment with the tool for future use.


The protein kinase ataxia telangiectasia- mutated and Rad3-related (ATR) is an important component of the DNA Damage Response (DDR) and a key mediator of the replication stress response (RSR). ATR is recruited to and activated by single-stranded DNA, which commonly forms as a consequence of replication stress (RS). ATR activation and signaling coordinates a multifaceted response to RS, however if left unresolved, replication forks may collapse, form double-strand breaks (DSB), lead to chromosomal rearrangements and eventually cell death. Several chemotherapeutic agents act by increasing RS in tumor cells, by directly damaging the DNA and/or depleting cellular resources required for DNA replication. Increased RS may also result from activation of oncogenes that drive dysregulated replication, a hypoxic environment, or from defects in other repair pathways even in the absence of exogenous DNA damaging insults. Inhibition of ATR activity in cancer cells disables the RSR, potentially enhancing the cytotoxicity of DNA damaging interventions and causing efficacy as monotherapy against tumors with reliance on ATR activity. M1774 is a potent inhibitor of ATR protein kinase with high selectivity towards other protein kinases. A broad range of antiproliferative activities (ranging from ~20 nM to >1 µM) was observed in a cancer cell line panel in vitro. M1774 showed pronounced synergy in combination with several DNA-damaging drugs and inhibitors of the DNA damage response. In vivo efficacy studies confirmed the combination potential suggested from in vitro studies. Pronounced combination benefit with complete tumor growth inhibition/regression was observed in combination with different chemotherapies or targeted DDR pathway inhibitors. Furthermore, M1774 showed pronounced activity as monotherapy in tumor models with gene mutations that result in a reliance on ATR activity. Clinical evaluation is ongoing to investigate M1774 as monotherapy and in combination with niraparib in patients with advanced solid tumors (DDRiver Solid Tumors 301, NCT04170153).
 Citation Format: Astrid Zimmermann, Heike Dahmen, Thomas Grombacher, Ulrich Pehl, Andree Blaukat, Frank T. Zenke. M1774, a novel potent and selective ATR inhibitor, shows antitumor effects as monotherapy and in combination [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2588.


An experimental study of gasification of palm kernel shell residues from the palm oil industry, as a potential hydrogen feedstock, is investigated. The gasification is conducted in a bench-scale fluidized bed gasifier with 55 mm diameter and 850 mm height. The operating conditions were studied in the following ranges: reaction temperature in gasification zone (750–1100 °C), feeding rate (0.20–1.21 kg/h), feedstock particle size (0.1–5 mm), and equivalence ratio (ER) (0.23–0.27). The increasing temperature and equivalence ratio was found to significantly influence the gas yield (up to 90 wt % conversion on the raw biomass) at 1000 °C and hence hydrogen composition (40 vol %). The feedstock particle size and feeding rate only showed minor influence. In conclusion, palm kernel shell is a potential candidate for hydrogen production.


In this paper, we analyze hybrid automatic repeat request applied to the transmission of video content over the wireless channel. Retransmission-based techniques are usually applied to queueing systems assuming a homogeneous flow of identical packets, which are all transmitted and possibly retransmitted in the same way. However, multimedia packets are encoded with incremental methods leveraging spatial and temporal redundancy and as such, they have different roles and should be treated differently by the retransmission mechanism. Therefore, our work considers a selective retransmission scheme with unequal error protection applied to a multimedia flow subdivided into distinguishable packets. We assume a binary channel with memory and non-zero round-trip time. We utilize discrete-time Markov chains to model the channel and the transmission/retransmission system. This enables a closed-form derivation of performance metrics via Markov analysis. Numerical results are discussed and possible implications on multimedia communications are evaluated.


Existing mobile photo crowdsensing approaches focus on the participant-to-server photo pre-selection, i.e., reducing the photo redundancy from participants to a server. The server may still receive plenty of photos for a target area. Yet, another important problem is to select a proper photo subset of an area from the server to a requester. This is a challenging problem because the selected subset with a small size should attain both coverage on the PoIs - Points of Interest (i.e., photo coverage of the area) and quality on the views (i.e., view quality). In this paper, we propose a novel and generic server-to-requester photo selection approach even when there are neither photo shooting direction information nor reference photos. A utility model is designed to measure photo merits of coverage and quality by exploiting photos' spatial distribution and visual representativeness. We present two photo selection schemes, basic and PoI number-aware, to maximize the photo selection utility with multiple levels of granularity. Experimental results on real-world datasets show that our basic scheme outperforms the baselines by an average of <inline-formula><tex-math notation="LaTeX">$33\%$</tex-math><alternatives><mml:math><mml:mrow><mml:mn>33</mml:mn><mml:mo>%</mml:mo></mml:mrow></mml:math><inline-graphic xlink:href="zhou-ieq1-2941927.gif"/></alternatives></inline-formula> and <inline-formula><tex-math notation="LaTeX">$18.7\%$</tex-math><alternatives><mml:math><mml:mrow><mml:mn>18</mml:mn><mml:mo>.</mml:mo><mml:mn>7</mml:mn><mml:mo>%</mml:mo></mml:mrow></mml:math><inline-graphic xlink:href="zhou-ieq2-2941927.gif"/></alternatives></inline-formula> on photo coverage and view quality, respectively. Our PoI number-aware scheme can yield an additionally 44.8 percent improvement on the photo coverage performance.


The paper explores various residential structures with special-shaped columns,determines possible structural distribution scheme according to building design requests,carries out an analysis by using structural design software,and comprehensively considers relative optimal scheme of seismic performance and structural ductility indicator,and finally concludes advantages of special-shaped column frame-shearing wall structure scheme,such as relatively good seismic ductility and great economy.


Nowadays, mobile operators in China mainland are facing fierce competition from one to another, and their focus of customer competition has, in general, shifted from public to corporate customers. One big challenge in corporate customer management is how to identify fake corporate members and potential corporate members from corporate customers. In this study, we have proposed an identification method that combines the rule-based and probabilistic methods. Through this method, fake corporate members can be eliminated and external potential members can be mined. The experimental results based on the data obtained from a local mobile operator revealed that the proposed method can effectively and efficiently identify fake and potential corporate members. The proposed method can be used to improve the management of corporate customers.


On 17 May 1952 an advanced party of three men skied to the central research station on the Juneau Ice Field. Early in July GUkey and four other members of the expedition were flown to the central station, followed by a special research party in August. During the season the expedition was visited by the Scandinavian scientists H. W:son Ahlmann and Sverre Petterssen, and by Richard U. Light, president of the American Geographical Society. The majority of the members of the expedition left the field between 22 and 28 August, but a few remained to complete the special investigations on the ice field and in Taku Valley until 24 September. Apart from observations to determine changes in the character and firmness of the previous winter's snow cover, and measurements of englacial temperatures, samples of neve were taken in order to determine their chloride content and for pollen analysis. The rates and directions of ice flow were observed, and gravimetric studies were made on the highest part of the ice field. The deformation of the 245-ft. (75-m.) aluminium pipe inserted in Taku Glacier in 1950 was measured. A portable 1500-watt electrothermic borer was tested and by this means englacial characteristics were studied to a depth of 171 ft. (52-1 m.). The differential movement between the top and bottom of the bore-hole proved to be very small. The ecologists studied the vegetation of nunataks and moraines. The surveyors occupied a series of new triangulation stations. Routine meteorological observations and measurements of ablation and radiation were made at three camps on the ice field. The geomorphologists made flights over the ice field and the surrounding area, and also worked in Taku Valley and at Twin Glacier Lake. Air support was provided in 1952 by the U.S. Air Force and by a chartered Piper Cruiser from Juneau. Two Grumman S.A. 16A Albatross amphibian aircraft made some sixty trial landings and take-offs at various altitudes between 3000 and 6000 ft. (900 and 1800 m.).


[Abstract] Ultraviolet (UV) irradiation induces helix distorting photolesions such as cyclobutane pyrimidine dimers (CPD) and pyrimidine-pyrimidone (6-4) photoproducts (6-4PP) which threaten genomic integrity if unrepaired. In mammals, nucleotide excision repair (NER) is the only pathway that removes UV-induced DNA damages. Here we describe DNA slot blot repair assay for quantitative detection of NER activity using DNA damage specific antibodies such as anti-CPD and anti-6-4PP. Briefly, genomic DNA irradiated with UV was isolated from cells, and the genomic DNA was vacuumtransferred to a nitrocellulose membrane using a Bio-Dot SF microfiltration apparatus (Bio-Rad). A monoclonal antibody that recognizes CPD or 6-4PP was applied to detect the remaining amount of photolesions in the genomic DNA. For loading control of even loading, DNA onto the membrane can be further analyzed by SYBR-gold staining.


Wavelength‐division multiplexed optical systems require an accurate knowledge of the cross‐phase modulation due to the Kerr effect, which generates a nonlinear phase modulation of each channel depending on the overall power in all of the other channels. In this letter, the spectral characteristics of cross‐phase modulation are investigated in multispan WDM optical systems, whose performance can be severely constrained by interference induced by this nonlinear effect. © 2001 John Wiley & Sons, Inc. Microwave Opt Technol Lett 31: 83–85, 2001.


Modular Multilevel Converter (MMC) provides promising features for medium/high voltage applications. In this paper, Shunt Active Power Filter (SAPF) with MMC is coupled to Medium Voltage (MV) non-linear load. The SAPF is controlled using instantaneous real and reactive power (p-q) theory to compensate the oscillating power and consequently the supply current harmonics resulting in supply current with acceptable Total Harmonic Distortion (THD). A MATLAB/ Simulink simulation model is used to investigate the performance of a 12-level MMC-SAPF compensating a MV diode converter.


Current trends in automation indicate a proliferation of programmable robotic arms in manufacturing plants. These arms typically have small local control computers and also are tied into larger computer systems for purposes of coordination and global control. This paper (1) analyzes such networks in terms of the principles of hierarchically intelligent control, (2) derives some design principles for a local control node in such network and (3) reports the implementation details and results for a prototype microcomputer control node.


Abstract Sergei Diaghilev is considered to be one of Europe's first public gay men. This article describes Diaghilev's evolution from a covert homosexual with an intent to marry, to the assertive homosexual he was in his later years, and frames it in the larger sociological and political context of the day.


Despite evidence supporting 3-option items, text authors and practitioners continue to advocate the use of four or five options. We designed an experiment to test further the efficacy of 3-option achievement items. Parallel tests of 3- and 5-option items were built and distributed randomly to college students. Results showed no differences in mean item difficulty, mean discrimination, or total test score, but a substantial reduction in time spent on 3-option items. The straightforward implication is that content validity may be boosted by writing additional 3-option items to tap more content.


In this research, f or controllingt he waveform displacement, a direct digitalcontrol is employed for the electro-hydraulic servo system's linear model with follow-up control. In this control system, the variable feed back gains of the velocity, the acceleration and its derivative at every sampling time are calculated by means of a digital computer, with the observed state variables of the electro-hydraulic servo system, and the manipulating signal is generated by the digital computer. Since the calculations of the variable feed back gains are simple, the follow-up control of the reference model can be carried out without any difficulty, when compared with the ordinary electro-hydraulic servo system. This control method was applied to an analog simulation circuit of a hydraulic servo motor and an experimental apparatus for verification, and the results were as follows: (1) As a reference model of the controlled object, an electro-hydraulic servo motor, the linear first and second order models can be used. From this discussion, arbitrary nth order reference model could be applied. (2) The input amplitude dependency of the dynamic characteristics on the electro-hydraulic servo system can be diminished. (3) Using the straight line approximation of the load pressure vs. flow characteristics of the spool valve, the calculating time can be shortened.


Among the flat-lying middle Paleozoic formations in the Leninogorsk ore field, layered bodies of porphyries of supposedly Early Carboniferous age occupy significant space. From the flanks toward the center of the ore field, these bodies gradually wedge out and branch in the section into a series of gently inclined apophyses (sills). Around two such apophyses, which in the southeast and northeast reach the center of the ore field (the Ridder-Sokol'noye deposit), a system of gently inclined veins, consisting of explosion-hydrothermal breccias and sericitolites (hydrothermalites), and also aureoles of microquartzites and pyritic polymetallic ores (the Western and Eastern oppositely directed oremagmatic clusters respectively) are developed. The ore zones in the clusters are located Immediately on the extension or above (and below) the segregations of hydrothermalites. The origin of the mineralization has been controlled by the injection, differentiation, and crystallization of porphyritic magmas, and by the r...


Warner's article discusses what might be thought of as genuinely lifelike in fiction, as against the conventions of realism and naturalism that she found in the fiction of the 1920s.


Abstract A three-dimensional finite element modelling of laser surface modification is presented. The design capabilities of the ANSYS parametric design language (APDL) were employed for this purpose. The model calculates transient temperature profiles and the dimensions of fusion and the heat-affected zone (HAZ). Model simulations are compared with experimental results, acquired on-line using an ultra-high shutter speed camera which is able to acquire well-contrasted images of the molten pool, and off-line, using metallographical analysis, that show very good agreement. The results are further discussed to provide directions for feedback and process control.


Abstract We study minimisation problems in L ∞ {L^{\infty}} for general quasiconvex first order functionals, where the class of admissible mappings is constrained by the sublevel sets of another supremal functional and by the zero set of a nonlinear operator. Examples of admissible operators include those expressing pointwise, unilateral, integral isoperimetric, elliptic quasilinear differential, Jacobian and null Lagrangian constraints. Via the method of L p {L^{p}} approximations as p → ∞ {p\to\infty} , we illustrate the existence of a special L ∞ {L^{\infty}} minimiser which solves a divergence PDE system involving certain auxiliary measures as coefficients. This system can be seen as a divergence form counterpart of the Aronsson PDE system which is associated with the constrained L ∞ {L^{\infty}} variational problem.


The paper expounds the requirements to teaching management work in senior vocational colleges in the new century. After analyzing the problems of teaching management works in senior vocational colleges, it puts forward many suggestions and measures.


Introduction: The gestational period is characterized as a time of transformation in women's lives, because, beyond the physical and physiological changes are also observed changes in emotional state. Thus, there are several changes that occur in the pregnant woman's body systems. Objectives: To assess the knowledge of pregnant women about proper positioning during AVD's. Method: The work it was a cross-sectional, quantitative in nature, held at the Reference Center for Social Assistance (CRAS). Pregnant women in all trimesters of pregnancy over the age of 18 years. The research was conducted through a semi-structured questionnaire with objective questions. Results: It has been confirmed, the knowledge of pregnant women about the correct placement in the realization of some postures in their activities of daily living such as: throwing, lifting, pulling and sweeping water, and not knowing about these sitting posture and grasp objects being in high places high importance at this stage, so getting clear the high levels of the same discomforts in this important phase. Conclusion: However, it is known and confirmed that pregnant women enrolled and treated at CRAS city MARIZOPOLIS-PB, are knowledgeable of some postures like throwing, lifting, pulling and sweeping water, which is extremely important to its current state. For both unaware of crucial positions for the day-to-day like to sit down and pick up objects in high places, the data show that they were unaware of the correct way. Therefore it is of paramount importance for the guidance of the same means of lectures, workshops and primarily during their attendance at antenatal.


Bacteriophages are the most predominant and genetically diverse biological entities on Earth. They are bacterial viruses which encode numerous proteins with potential antibacterial activity. However, most bacteriophage-encoded proteins have no assigned function, hindering the discovery of novel antibacterial agents. In particular, there has been a growing interest in exploring recombinant bacteriophage depolymerases from the fundamental standpoint, but mostly for biotechnological applications to control bacterial pathogens. Due to the lack of efficient identification tools, we developed PhageDPO, the first developed tool that predicts depolymerases in bacteriophage genomes using machine learning methods. Availability and implementation PhageDPO was integrated into a Galaxy framework available online at: bit.ly/phagedpo.