The prairie population of the loggerhead shrike (Lanius ludovicianus excubitorides) is dependent upon two characteristics of a grassland landscape that require specific management to maintain: shrubs taller than 1.8 m tall for nesting and tall grass for foraging. The purpose of this study is to measure the landscape variables that are important to loggerhead shrike persistence at landscape spatial scales to help understand the impact of management decisions and seek alternative solutions if required. Results indicated that shrikes prefer to nest in scattered shrubs, particularly thick or thorny species. Reflectance based vegetation indices differed in their performance dependent upon the vegetation variables used. L-ATSAVI and ATSAVI are the best LAI estimators, while MSAVI2 is good to estimate the shrub cover. A logistic regression model, using loggerhead shrikes active or inactive nesting as the dependent variable and biophysical, topographical, and remotely sensed data extracted from both ground and space, as the predictors was developed. The predictive performance of the selected models was shown to be high, indicating a good fit of the model to the data. Further analysis showed that all the variables considered (Dead cover in tall shrub habitat and ATSAVI) had significant, independent contributions towards explaining the variation in the dependent variable. The selected model clearly delineated areas predicted as highly suitable loggerhead shrikes habitat.


Objective To evaluate selective angiographic diagnosis and superselective embolization of intractable epistaxis in 21cases.Methods The seldinger technique was used in a ll patients.The catheter was introd uced via femoral artery on the right side.Selective angiographic analysis and di agnosis were performed.Superselective an-giographic embolization with silk t hread in diamend form 140to 250um was performed in bleeding vessels.Results All cases achieved satisfactory effect.During the follow -up 2to 12mont h,no patients recurrence nose bleed ing.8cases were operated in 1week.Bleedi ng reduced sharply in operation,and difficulty of operation cut down and success rate of operation was increa sed.Conclusions Selective angiographic diagnosis,and Superselective angio-graphic embolization,and suitive s ilk thread granular,and appropriate embolic speed is critical for successful treat-ment of massive epistais,Maxillary artery embolization is safe,effective,and uncomplicated Interventio nal em-bolization has afforded a new methed for acoustic -nasola -larynxologic operation.


Purpose – Responding to the recent split in the US labor movement, this paper aims to argue that learning must become an integral part of a progressive union devoted to organizing.Design/methodology/approach – This paper traces the evolution of vocational education in US industrial unions and critiques it in light of the challenges facing labor today.Findings – The paper finds that vocational education in US industrial unions is a negotiated benefit aimed at meeting the instrumental needs of individual union members. The evolution of this model was inevitable given the US labor relations context within which it emerged. However, significant changes in US political economy call for a new model of vocational education in unions. Rather than learning as a service, Learning to Organize challenges unions to put learning in service of the broader, collective aim of renewed labor power.Practical implications – The paper shows that union leaders need to reframe their views of vocational learning and its role in u...


Lower limb exoskeleton robot can be used to enhance human body function, rehabilitation training and assist walking. Based on the biomechanical characteristics of human lower limbs, a wearable lower limb exoskeleton robot without auxiliary tools was designed. The mechanism design principle and process of wearable exoskeleton of lower limb are described. The lower extremity exoskeleton assisted walking experiment with and without crutches was performed on healthy subjects. Experimental results showed that the exoskeleton robot could assist human walking without any auxiliary tools, and the design of the lower limb exoskeleton was feasible.


Objective To study some creative forms of Chinese elements in the TV advertising of liquor. Methods Creative forms of Chinese elements in the TV advertising are divided into three categories,using the actual cases of alcohol advertising,it analyzed the creative form of Chinese elements in the alcohol advertising. Conclusion It proposed 7different creative combination forms of Chinese elements in the TV advertising of liquor,consciously using different Chinese elements combination in the creative advertising,to better express the advertising strategy to attract the attention of consumers.


The invention discloses a method for adopting a solid-liquid two-step fermentation technique to produce feeding lactobacillus acidophilus, which belongs to the microorganism technical field. The method comprises: firstly, culturing a strain of yarrowia lipolytica, secondly, fermenting and culturing solid of the yarrowia lipolytica, thirdly, culturing the strain of lactobacillus acidophilus, fourthly, fermenting and culturing liquid of the lactobacillus acidophilus, fifthly, absorbing and packaging lactobacillus acidophilus fermentation broth, and the like. The method of the invention adopts cheap and easily obtained agricultural byproducts such as soybean meal, wheat bran, corn meal and the like as raw materials to produce the feeding lactobacillus acidophilus through the solid-liquid two-step fermentation, the method has the characteristics of low production cost, rapid growth and reproduction, high yield and the like, and the method overcomes the difficult problem that previous feeding lactobacillus acidophilus has over high production cost and can be extended and applied in livestock and poultry feedstuff production enterprises.


Milk is produced by the mammary gland of mammals to feed their young ones. Milk is an important nutrient-rich beverage that benefits our health. This article aims to study the effect of Asparagus racemosus root powder on milk yield and milk composition. The experiment was performed to determine the milk yield and milk protein, fat, total milk solid, and milk acidity after using Asparagus racemosus as a food supplement. The animals were selected based on purposive sampling to select lactate buffalo to avoid or reduced the error. During the experiment, animals fed in three phases; control, treatment, and the residual phase. In control phase animal diet normal ration, whereas in the treatment phase, a buffalo was diet 120 gram of Asparagus racemosus root powder in addition to its normal diet per buffalo per day. While in the residual phase, the animal was diet only normal ration. Each phase has been 5 days. The Milk collected from lactating buffalo in three phases; control, treatment, and the residual period. Each period has been five day. We also measured milk yield per day per buffalo. About 50 ml of milk was collected from each five buffalo every morning for 15 days. The data was analyzed through one way ANOVA and T-test using the procedure of statistical software. The result indicates that the diet was statistically significant effecting on milk yield at 5% (0.0196), protein at 1% (0.0113) and fat at 1% (0.0007) while the insignificant effect on milk acidity p >30 (0.3909) and total solid p >80 (0.8904). Therefore, feeding Asparagus racemosus, positively affects milk yield and milk protein and milk fat content.


Background: We previously identified a panel of five miRNAs associated with biochemical recurrence and metastasis following prostatectomy based on NGS-based whole miRNome discovery and qPCR-based validation analysis. In this analysis, we examine the effect of miR-139-5p, one of the down-regulated miRNAs identified in the panel, in greater detail. Methods: Using a cohort of 585 patients treated with radical prostatectomy, we examined the prognostic significance of miR-139 (dichotomized around the median) using the Kaplan Meier method and Cox proportional hazard models. We validated these results using The Cancer Genome Atlas (TCGA) data. We created cell lines that over-expressed miR-139 or transiently transfected cells using miR-139 mimics for functional assays. Finally, we examined pathways through which miR-139 may function using prediction algorithms and confirmed targets by Western blotting and reporter assays. Results: MiR-139 down-regulation was significantly associated with a variety of accepted prognostic factors in prostate cancer, including Gleason score, pathologic stage, margin positivity and lymph node status. MiR-139 was associated with prognosis: the cumulative incidence of biochemical recurrence and metastasis were significantly lower among patients with high miR-139 expression (p=0.0004 and 0.038, respectively). After adjusting for known prognostic factors, patients with high miR-139 expression had significantly lower risk of recurrence (HR 0.77, 95% 0.58-1.04). Validation in the TCGA dataset showed a significant association between dichotomized miR-139 expression and biochemical recurrence (OR 0.52, 95% CI 0.33-0.82). Over-expression of miR-139 in prostate cancer cells led to a significant reduction in cell proliferation and migration compared to control cells, with cells arrested in G2 of cell cycle. IGF1R, RUNX1 and AXL were identified as potential gene targets of miR-139 based on their association with prostate cancer growth pathways and multiple miRNA binding site prediction tools. The reporter assays using luciferase gene constructs containing the predicted miRNA targeting sequence from IGFR1 and RUNX1 verified them as direct targets of miR-139. Furthermore, Western blotting of prostate cancer cells demonstrated RUNX1 and AXL expression were inhibited by miR-139 treatment, which was reversed by addition of miR-139 antagomir. Examination of the molecular mechanism of growth inhibition by miR-139 revealed the downregulation of activated Akt and cyclin D1, with upregulation of the CDK inhibitor p21. Conclusions: miR-139 is associated with improved prognosis in patients with localized prostate cancer, which may be mediated through inhibition of IGF1R, RUNX1 and/or AXL and their associated growth signaling pathways. Citation Format: Tania Benatar, Robert K. Nam, Elizabeth Kobylecky, Yutaka Amemiya, Arun K. Seth. miR-139 is associated with improved prognosis in patients with localized prostate cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3554.


Disclosed is a glass plate package body wherein a glass plate stack formed by stacking a plurality of glass plates with a sheet between the plates is packed by a package container, and wherein the glass plate has a thickness of 0.7 mm or less, the glass plates are vertically stacked to be tilted relative to the vertical direction to form the glass plate stack, and the deviation in the thickness of the glass plate stack is 10% or less.


The author would like to express his thanks to: Dr. Harding le Riche, Professor of Biometrics and Epidemiology, University of Toronto; Dr. E. Lewellyn Thomas, Associate Director of the Institute of Biomedical Electronics, University of Toronto; Dr. Walter Zingg and Dr. E. Nagy of the Research Institute of The Hospital for Sick Children, for their advice and constructive criticism. Mr. Glen Jones of the Department of Biometrics, University of Toronto, for his statistical analysis. Mr. Arthur Smialowski, Director of Photography, St. Michael's Hospital, and Mr. Barry Skopit of the Polaroid Company of Canada, for their advice on photography. Mr. S. W. Wright, Director of Photography, The Hospital for Sick Children, for his help on the Densichron results. Messrs. William Wilson and Brian Watkins of the Department of Research Histology, The Hospital for Sick Children, for their advice and for histological preparations. Mr. J. E. MoCutcheon, J. E. McCutcheon Ltd., for his assistance in photographic supplies. Mrs. Lita Graham, Miss Susan Allison and Mr. Leslie Starmer for their planimeter readings and drawings.


In this paper, we propose a discriminative multitask sparse learning scheme for object tracking in a particle filter framework. By representing each particle as a linear combination of adaptive dictionary templates, we utilise the correlations among different particles (tasks) to obtain a better representation and a more efficient scheme than learning each task individually. However, this model is completely generative and the designed tracker may not be robust enough to prevent the drifting problem in the presence of rapid appearance changes. In this paper, we use a Conditional Random Field (CRF) along with the multitask sparse model to extend our scheme to distinguish the object candidate from the background particle candidate. By this way, the number of particle samples is reduced significantly, while we make the tracker more robust. The proposed algorithm is evaluated on 11 challenging sequences and the results confirm the effectiveness of the approach and significantly outperforms the state-of-the-art trackers in terms of accuracy measures including the centre location error and the overlap ratio, respectively.


s and interim results should be considered, bearing in mind that contact with the study authors may be required to obtain full study details. The effects of including any data from abstracts alone should be carefully considered, since differences often occur between data reported in conference abstracts and their corresponding full reports, although differences in results are seldom large. The identification of ongoing studies is important for a number of reasons. They may provide a useful starting point for subsequent reviews and updates; they may also improve the quality of conclusions about future research by indicating where new research has already commenced. Including data from unpublished studies is important in minimizing bias. However, this can be time-consuming. The practical difficulties of locating and obtaining information from unpublished studies may, for example, make the ideal of including relevant unpublished studies unachievable in the timescales available for many reviews. Types of participants/Population When expanding the title and objectives/questions through the criteria for inclusion, reviewers will need to consider whether the whole population of people with a specific condition should be included, or if the population will be limited to specific subsets. Specific reference to population characteristics (participants' gender, age, disease severity, co-morbidities, socioeconomic status, ethnicity, geographical area) either for inclusion or exclusion should be based on a clear, scientific justification rather than based on unsubstantiated or personal reasoning. The included population should be relevant to the population to which the review findings will be applied. If the inclusion criteria are broad it may be useful to investigate subgroups of participants. Where analysis of participant subgroups is planned this should be specified in the protocol. Important details for types of participants are: specific disease/conditions, stage of the disease, severity of the disease, co-morbidities, age, gender, ethnicity, previous treatments received, previous condition, explicit standardized criteria for diagnosis, setting (for example, hospital, community, outpatient), who should make the diagnosis of the specific disease, other important characteristics of participants (such as for example different response to the treatment). Examples of types of participants: patients with hyperthyroidism and solitary thyroid nodule, patients with morbid obesity with serious comorbidity, patients age 80 or over with abdominal aortic aneurysm, patients with severe claudication, patients on liver transplant waiting list, symptomatic lung cancer men aged 65-74, patients with severe ileocolonic Crohn's disease, heavy smokers eligible for lung resection. Examples for more specific details for types of participants: ■ Pathologically verified epithelial ovarian cancer, Stage III suboptimal residual disease (>1 cm residual mass), all patients with Stage IV disease, no prior radiotherapy or chemotherapy. Borderline cancers excluded. ■ Histologically or cytologically proven adenocarcinoma of the breast, metastatic disease with measurable lesions, prior hormone therapy, radioor immunotherapy permitted Synthesizing Economic Evidence P1: OSO LWBK991-Book7 LWBK991-Sample-v1 September 12, 2011 13:1 Synthesizing Economic Evidence 27 but this had to be stopped on study entry, prior adjuvant therapy permitted if at least 3 month previously, no exposure to anthracyclines or taxanes, no chemotherapy for advanced disease. The criteria for considering types of people included in studies in a review should be sufficiently broad to encompass the likely diversity of studies, but sufficiently narrow to ensure that a meaningful answer can be obtained when studies are considered in aggregate. Types of Interventions Where possible, the intervention should be described in detail, particularly if it is multifaceted. The nature of the intervention(s) explored in the review may be framed in very broad terms or may be more specific. Elements usually specified include the nature/type of the intervention, the person(s) delivering the intervention(s) and the setting in which the intervention is delivered. Important details for types of interventions are: explicit and clear description of interventions, dosage, intensity, mode of delivery, types of personnel who deliver it, frequency of delivery, duration of delivery, timing of delivery, critical doses/intensity, co-interventions. Examples of types of interventions: thyroid lobectomy, gastric banding, endovascular repair, duplex ultrasound and angioplasty, liver transplantation, screening for abdominal aortic aneurysms, annual CT screening. Stating a particular comparator limits the scope of a review, assisting with ensuring a clear focus for determining inclusion and exclusion once searching and appraisal is complete. However, when a broader question is being considered, particularly one where multiple interventions exist, limiting the types of comparators may not be appropriate or desirable. Where an intervention has not been subject to previous economic evaluation, the comparator can reasonably be identified based on either a known gold standard, or an approach which is considered to be "current practice". Important details for comparators are: explicit and clear description of interventions, dosage, intensity, mode of delivery, types of personnel who deliver it, frequency of delivery, duration of delivery, timing of delivery, critical doses/intensity, co-interventions. Examples of types of comparators: Radioactive iodine (comparator for thyroid lobectomy), no surgery (comparator for gastric banding), open operative repair (comparator for endovascular repair), supervised exercise program (comparator for duplex ultrasound and angioplasty), medical treatment (comparator for liver transplantation), no screening (comparator for screening for abdominal aortic aneurysms). Types of outcomes The types of outcomes and the timing of outcomes measurements are key decisions in development of a systematic review protocol. There should be a list of all the outcome measures to be considered. Note that outcome measures might be primary or secondary. The background should provide enough information to justify the outcomes included and potentially those that were not included. The outcomes need to be measurable and appropriate to the review objective. It is useful to list outcomes and identify them as primary or secondary, The Lippincott-Joanna Briggs Institute Series on Synthesis Science in Healthcare: Book 7 P1: OSO LWBK991-Book7 LWBK991-Sample-v1 September 12, 2011 13:1 28 SECTION 1 The Synthesis of Economic Evidence short-term or long-term, relative or absolute. The outcome may be described in relation to the type of review. Therefore the appropriate specific outcomes should be described in relation to cost-minimisation analysis, cost-effectiveness analysis, cost-benefit analysis or cost-utility analysis. There may be one or a range of outcomes of interest depending on the nature of the topic and planned scope of the review. In identifying which outcomes will be specified, it is useful to consider the interests of the target audience. Types of costs In economic evaluations, the costs accruing from an intervention depend on whose perspective it is from. Whenever possible all relevant costs should be included and presented by perspective and categorised by type. Types of summary measures There are different incremental summary economic measures reported in economic evaluation studies: incremental net present value of benefits (in CBA), the incremental cost-effectiveness ratio (in CEA), and the incremental cost-utility ratio (in CUA), and also different average summary measures. Average summary measures should not be used to compare interventions. In a CBA, all costs and benefits are measured in monetary terms and then combined into a summary measure. Examples of such summary measures for CBA are the Net Present Value (NPV) and the Benefit-Cost Ratio (BCR). Types of benefits The success or failure of an intervention will usually be assessed in terms of differences in mortality or morbidity or quality-adjusted life years in the populations treated. Primary outcomes are likely to include measures of mortality and morbidity but other outcomes may also be of importance, for example measures of quality of life and participants' subjective experiences of pain or physical functioning. A review should explore a clearly defined set of relevant outcomes and it is important to justify each outcome included. The use of surrogate outcomes may be misleading, giving an over or underestimate of the true clinical outcome. In economic evaluations conducted alongside trials, due to the short study timeframe, typically, surrogate outcomes are collected. Additionally, in many economic modeling studies, intermediate outcome parameters are used to extrapolate final outcomes. Decisions about whether to consider surrogate outcomes should therefore be informed by available evidence about associations between the surrogate and the outcome of interest. Often, surrogate outcomes are included only where a study also reports a relevant clinical outcome. When defining the timing of outcome measurement, authors may consider whether all time frames or only selected time-points will be included in the review. Economic evaluations carried out alongside trials measure short to medium term cost-effectiveness effects whereas models extrapolate costs and effects often over a lifetime time horizon. It is important to give the timing of outcome measure considerable thought. It may be helpful for review authors to consider those measures used in related reviews when defining the type and timing of measurement within their own review. In addition, several clinical areas are developing agreed Synthesizing Economic Evidence P1: OSO LWBK991-Book7 LWBK991-


PURPOSE: To further reinforce a hit enable band by an extended barrel length part so as to give the highest speed to a ball by providing a cylindrical barrel which has a specified outside diameter of a hit corresponding band and is extended straight in the longitudinal direction with an end cover including an inserted sleeve part and an inside reinforcing rib for giving additional strength to the cylindrical barrel. CONSTITUTION: An aluminium bat includes a cylindrical barrel 12, a grip 14 a knob 16 of the grip end and an end cover 18 at the forward end. The cylindrical barrel 12 has an outside diameter from 2.5/8 inch (66.7 mm) to 2.3/4 inch (69.9 mm), and is extended from the forward end 26 of the cylindrical barrel for receiving an end cover 18 on the cylindrical barrel inner surface having a cylindrical barrel inside groove 27 straight to the inner and outer surfaces. The end cover 18 includes a sleeve part fitted to the forward end part 28 of the hard end cover and the forward end part 26 of the tube 12. The inside end cylindrical part 54 enters the inside groove 27 of the cylindrical barrel 12 of a bat with the sleeve part of the end cover 18 put inside the tube 12, and is confined inside the tube 12 by the inside shoulder part 48 for forming a fixing rib on the end cover 18.


Objective:To establish a HPLC fingerprint of iridoids and crocetin derivatives in Gardenia Fructus(GF) for the evaluation of the intrinsic quality.Method:Chromatographic separation was carried out by an Inertsil ODS-SP column(4.6 mm×250 mm,5 μm) and gradient elution was performed by mobile phase containing MeOH and 0.1% formic acid aqueous solution.The flow rate was 1.0 mL · min-1,the column temperature was maintained at 25 ℃,and the separated compounds were detected at a variable wavelength.The similarity evaluation software was adopted to analyze the similarities of 10 batches of commercial GF.Result:A consistent HPLC fingerprint pattern containing 20 common peaks was obtained and two major components were identified as geniposide and crocin-1,and the results of similarities of ten batches were range from 0.95 to 0.99.Conclusion:The established fingerprint method which reflect more chemical composition information of GF had good precision,reproducibility,stability,and could provide as an effective tool for the quality control of GF.


success inside Zimbabwe by guerillas of the Joint Military Command, assisted by Frelimo. Black and white lives have been lost, and the battle sustained for at least four months. Obviously this onslaught may not prove a harbinger of ultimate victory, but the struggle continues. Similarly, Gibson's partiality for Jonas Savimbi's Unita and Paulo Gumani's Coremo in Angola and Mozambique is more than idiosyncratic. It may have blinded him to the comparative successes of rival groups, and thus to the potential, unromanticized, impact of the movements of liberation generally. They have thus far aborted the attack, but Gibson's failure to transcend sniping superficiality leaves us needing a more informed study of the process of liberating colonially-held Africa.


In polymer electrode fuel cells the main component is the membrane/electrodes assembly (MEA). The diffusion layer is the principa l component of the MEA being a composite material, constituted of carbon powder to which polytetrafluoroethylene (PTFE) is added to increase hydrofobicity, fundamen tal characteristic related to water transport in the system. Over difusion layer is dep osited a catalitic layer formed by platinum supported on carbon powder to which a Nafi on solution is additioned. These layers present inhomogeneous roughness, porous and surfaces of the complex characterization. The object of this work is to ada pt characterization methods for these layers with the aim of the determinate their wettab ility, morphology and porosity, as well as to otimaze the MEA fabrication parameters. The produced MEAs were tested using a fuel cell prototype fabricated at PUCRS. For the determination of the surface wettability th e contact angles were measured by drop water method using an optical micr oscope and a video camera. The advancing ( θa) e receding ( θr) angles were measured and used to estimate the hy st resis (∆θ = θa θr) and the equilibrium angle. For morphologic and c omposition characterization of the layers and subtracts, scan ning electronic microscopy (SEM) and energy dispersive spectroscopy (EDS) were used. The porosity was measured by imbibing n-heptane into all pores (hydrophilic and hydrophobic) and water into hydrophilic pores of the substrates and composites. Three MEAs were fabricated by optimized process. The optimized parameters were: c onstituents composition (carbon powder and PTFE), subtract type (carbon paper or ca rbon cloth), cleaning and thermal procedures. These MEAs were tested in a fuel cell g enerated powers were compared between fabricated assemblies and with commercial M EAs. Morphology study proved that PTFE incorporation int o carbon power is a critical step on diffusion layers fabrication. A good compro mise between a adequate recover


Distributed consensus requires the consent of more than half of the congress to produce irreversible results, and the performance of the consensus algorithm deteriorates with the increase in the number of nodes. This problem can be addressed by delegating the agreement to a few selected nodes. Since the selected nodes must comply with the Byzantine node ratio criteria required by the algorithm, the result selected by any decentralized node cannot be trusted. However, some trusted nodes monopolize the consensus node selection process, thereby breaking decentralization and causing a trilemma. Therefore, a consensus node selection algorithm is required that can construct a congress that can withstand Byzantine faults with the decentralized method. In this paper, an algorithm based on the Byzantine agreement among decentralized agents to facilitate agreement between decentralization nodes is proposed. It selects a group of random consensus nodes per block by applying the proposed proof of nonce algorithm. By controlling the percentage of Byzantine included in the selected nodes, it solves the trilemma when an arbitrary node selects the consensus nodes.


The article analyses the research activities of the Department of Advertising and Public Relations of the Institute of Journalism at Borys Grinchenko Kyiv University in the period from 2017 to 2021. Academic researchers are not just included to the activities of modern universities, but are prioritised, because this kind of activity significantly affects the position of university in prestigious rankings, whereas ratings are among of the arguments in favor of the entrant's decision to choose a university for further study. During the period from 2017 to 2021, the Ministry of Education and Science of Ukraine and similar government agencies in the United States and the EU, as well as many grant-making organisations in the field of education, declared the need to develop research activities of universities. It has become the responsibility of most Ukrainian lecturers to publish articles indexed in the Scopus and Web of Science scientometric databases. Research activities are particularly difficult for practitioners who are involved in teaching due to their experience in the business sector of national economy. According to the strategy of student-centered and practice-oriented learning, many such specialists had been involved in the activity of the Department of Advertising and Public Relations at the Institute of Journalism. Advertising and public relations are mostly applied areas, not traditional academic disciplines, unlike many other specialisations of academic departments in Ukrainian universities. Meanwhile, modern entrants show more interest in applied areas of social sciences than in theoretical issues. Therefore, the analysis of the research work of the Department of Advertising and Public Relations may be of particular interest to teachers and administrators working in higher education institutions. The main objectives and results of research work of the department are systematised on the basis of academic research papers, mass media publications of this department lecturers, as well as with the help of several special interviews with employees of the Institute of Journalism. The main achievements of key figures in research activities of this department are highlighted in the context of the common scientific theme of the institute: "Modern Media Studies in Educational and Scientific Discourses" and the individual research interests of the lecturers. The article provides an overview of the most important academic publications of them. A considerable attention is paid to the analysis of achievements and theoretical issues of academic research cooperation between teachers and students. The article emphasises the need to unite the efforts not only of the vast majority of Ukrainian academic researchers and educators, but also of the majority of Ukrainian society, as well as its truly pro-Ukrainian foreign partners, to reform the system of administration of research work and high education in Ukraine


Lightweight sandwich panels (LWSP) have been used in various sectors of construction and transportation industries. However, due to the cost and complexity of the manufacturing process, their usage in high level sport equipment has been somewhat neglected. This study investigates the feasibility of using a wood veneer sandwich panel to construct the playing surface of a table tennis table. The effects of material parameters, such as the face sheet thickness, core configuration, core thickness and surface coating, on the dynamic friction coefficient and coefficient of restitution, which ultimately dictate the speed, bounce and spin of the ball, will be examined. All results from characterisation of the LWSP table using the International Table Tennis Federation (ITTF) standards will be compared with those from commercially available tables. The material parameters identified to yield the most consistent and favourable characteristics for a table tennis game will be applied for construction of a full size demonstration table.


Abstract In the present paper, we introduce the notion of generalized multiplicative derivation in a near-ring N and investigate commutativity of 3-prime near-rings, showing that certain conditions involving generalized multiplicative derivations force N to be a commutative ring. Finally some more results related with the structure of these derivations are also obtained.


The component and damping mechanism of polymer damping coatings was summarized.The modified methods of polymer,such as copolymerization,blending and interpenetrating network(IPN),and development of polymer damping coatings was introduced.In this paper,the universal resins and fillers,the modified methods of interpenetrating networkand latex interpenetrating network(LIPN),and the environment friendly hydrophilic polymer damping coatings were introduced in detail.


We have examined the locations and radiation patterns of the foreshocks to the 4 February 1978 Haicheng earthquake. Using four stations, the foreshocks were located relative to a master event. They occurred very close together, no more than 6 kilometers apart. Nevertheless, there appear to have been too clusters of foreshock activity. The majority of events seem to have occurred in a cluster to the east of the master event along a NNE-SSW trend. Moreover, all eight foreshocks that we could locate and with a magnitude greater than 3.0 occurred in this group. The're also "appears to be a second cluster of foresfiocks located to the northwest of the first. Thus it seems possible that the majority of foreshocks did not occur on the rupture plane of the mainshock, which trends WNW, but on another plane nearly perpendicualr to the mainshock. plane. This inference is supported by differences among the radiation patterns of the foreshocks. We also examined the radiation patterns of the foreshocks, primarily through the amplitude ratios of P and S waves (Ap/As) recorded at each station. While the ratios were relatively constant at the more distant (A=100-200 kilometers) stations, two very different waveforms were recorded throughout the sequence at Yingkou (A=20 kilometers). Calculations of the amplitude ratios expected from the (not very different) fault plane solutions of the mainshock and some of the largest foreshocks showed that two different waveforms should be recorded at Yingkou. A definite correlation could not be made between the two mechanisms and the different location clusters.


This paper develops an accurate yet interpretable machine learning framework for predicting field failures from time-series diagnostic data with application to datacenter hard disk drive failure prediction. Interpretable models are accountable: model reasoning can be verified by a domain expert for critical reliability tasks. We develop an attention-augmented recurrent neural network that visualizes the temporal information used to generate predictions; visualizations correlate with physical expectations. Finally, we propose a clustering-based method for discovering failure modes.


The cross sectional study was performed to find out the incidence of β-Thalassemia trait in pregnant women of south western Maharashtra from October 2007 to August 2011. The study was conducted at Government Medical College, Miraj. In this study we included 1279 pregnant women from Obstetrics & Gynecology OPD, EDTA anti-coagulated whole blood samples were collected for on-site Naked Eye Single Tube Red cell Osmotic Fragility Test (NESTROFT) testing. The screening of β thalassemia trait was done on NESTROFT with 0.36% freshly prepared saline, and β thalassemia trait status of all NESTROFT positive subjects was confirmed by quantitaion of Hb A2 level, by microcolumn chromatography. Out of 1279 women the NESTROFT was positive for 213 subjects, and Hb A2 level was more than 3.5% in 38 subjects, which is a determinant of β thalassemia trait. With a 3.1% rate of β thalassemia trait, this indicates need to study beta thalassemia carrier status in the child bearing group, as a primary step to prevent the birth of beta thalassemia major.


The main properties of the observed extrasolar planets are reviewed with respect to their relevance to the formation scenario of planetary systems. Results of numerical computations of embedded planets in viscously evolving disks are presented. Emphasis is given to the accretion and migration process. New calculations on inviscid disks are shown.
The second part of the talk concentrates on resonant planetary systems. Among the observed extrasolar systems there are 3 confirmed cases, Gl 876, HD 82943 and 55 Cnc, where the planets orbit their central star in a low order mean motion resonance. Results of numerical simulations modeling the formation and evolution of such systems are presented.


Intrusive mental imagery is a transdiagnostic process (1) present in many psychological disorders including trauma-related disorders; anxiety, mood, and eating disorders; as well as severe mental health problems, such as bipolar disorder and psychosis. In this article, we summarize some of the current literature on intrusive images and then argue that one critical way in which they maintain disorders is through their representation and relationship with patients' sense of self. We conclude by briefly discussing the treatment implications of this position.


It' s a key problem to design an effective control strategy for unit plant coordinated control system to improve the automatic control level in thermal engineering. The algorithm of the generalized predictive control (GPC) is extensively used in academic and industrial fields for its simple modular parameters, distinctive robustness and stability. In this paper, from the model of a 500MW boiler-turbine coordinated control system, the multi-variable GPC control strategy has been designed according to this linearized model. The simulation results indicate that, compared with PID, the proposed method can not only track the input set value smoothly and rapidly with smaller overshoot and shorter adjusting time, but also has stronger robust.


D ynam icalfour-point susceptibilities m easure the extentofspatialcorrelations in the dynam ics of glass form ing system s. W e show how these susceptibilities depend on the length scales that necessarily form part oftheir de nition. The behaviour ofthese susceptibilities is estim ated by m eansofan analysisin term sofrenewalprocesseswithin the contextofdynam ic facilitation. The analytic resultsare con rm ed by num ericalsim ulations ofan atom istic m odelglass-form er,and of two kinetically constrained m odels. Hence we argue that the scenario predicted by the dynam ic facilitation approach isgeneric.


We enjoyed the editorial by Butterworth and Hammon (1) on lidocaine protection against postcardiopulmonary bypass cognitive dysfunction. We disagree, however, with their assertion that it is a "reasonable assumption that strokes and neurobehavioral deficits result from similar brain injury mechanisms." There is now ample evidence that a substantial percentage of patients undergoing even routine general surgical procedures experience cognitive impairment for weeks or months thereafter (2,3). The etiology of this neurobehavioral impairment is unknown, but there is little reason to think it is due to subclinical structural neurologic injury, since, with the exception of cardiac, neurological, and a few orthopedic surgical procedures, stroke-promoting events such as emboli are unusual. Moreover, efforts to link worrisome systemic physiologic events associated with anesthesia such as hypotension and hypoxemia with postoperative cognitive dysfunction have been unsuccessful (2,3). Finally, although we do not expect the authors to be aware of soon-to-be-published data, we have laboratory evidence that isoflurane–nitrous oxide anesthesia impairs learning for several weeks in young and old rats (4,5), suggesting general anesthesia itself may affect neurochemical cascades mediating memory for longer than previously realized. Therefore, while stroke can produce cognitive impairment, there is almost certainly more to postoperative cognitive impairment than clinical or subclinical stroke.


Corporate Social Responsibility refers to the practice of conducting business in a manner which links it to ethical values, compliance with legal requirements and most importantly, respect for people, communities and the environment. Corporate Social Responsibility (CSR) is a concept whereby organizations consider the interests of society by taking responsibility for their activities on customers, employees, shareholders, communities and the environment in all aspects of their operations. Corporate Social Responsibility allows business organizations to develop responsible attitude toward the society and the environment and to behave ethically and contribute to economic development of the nation.


Liver wounds were experimentally induced in dogs. The wounds were dressed with catgut suture, suture and fibrinous sponge and ester n-butyl alfa-cyanoacrylic acid in aerosol form obtained laboratorially at the Institute of Organic Chemistry--Polish Academy of Sciences in Warsaw. The basis for evaluation were clinical observations of the operated animals, morphological and biochemical examination of blood and dissection. It was found that the best results were achieved with the surgical glue. Application of this monomer in aerosol form to join and dress liver wounds helps to close them tightly in a short time and obtain full hemostasis and stop bile leaking.


The ESR line shapes of ${(\mathrm{N}\mathrm{H}}_{4}{)}_{2}{\mathrm{ZnCl}}_{4}$ crystals doped with ${\mathrm{Mn}}^{2+}$ were studied in a range of temperatures from 160 to 80 \ifmmode^\circ\else\textdegree\fi{}C. It was found that the crystal undergoes an incommensurate phase transition at 135 \ifmmode^\circ\else\textdegree\fi{}C and an incommensurate-commensurate transition at 92 \ifmmode^\circ\else\textdegree\fi{}C. The form and temperature dependence of the ESR spectra throughout these changes are in good agreement with the predictions of the phase-soliton theory. The parameters ${h}_{1}$ and ${h}_{2}$ determining the variation of the resonant magnetic field show a power-law behavior as a function of temperature. The critical exponent \ensuremath{\beta} of this crystal was determined two independent ways to be $0.36\ifmmode\pm\else\textpm\fi{}0.03.$ The soliton density does not change significantly during the whole incommensurate phase and drops abruptly to zero at the incommensurate-commensurate transition, a behavior that is quite different from those of other incommensurate systems.


New simple hydrogelators containing the structural features of cyclic amino acids were investigated for water gelation through H-bonds from carboxylic acids and amino groups, showing for the first time the use of a single amino acid as a hydrogelator. The hydrogels were used for the synthesis of Pt and Ir nanoparticles, showing for the first time that a supramolecular hydrogel was used for the in situ formation of Pt and Ir nanocrystals.


Customer satisfaction is considered as the "cornerstone" of marketing, it is often presented as the ultimate goal of marketing function. According to Giese and Cote [2000], consumer satisfaction is an emotional or cognitive response. Researching the role of emotions in shaping the concept of consumer satisfaction presents theoretical and practical interest.


The recent mapping of the genome of the nonconventional oleaginous yeast species Yarrowia lipolytica has sparked interest in its usefulness as a model for fat metabolism and as an alternative to Saccharomyces cerevisiae. However, for Yarrowia lipolytica to be more effective as a model organism, more information must be obtained about its metabolism. This study focused on the gene that encodes NADPH‐dependent glutamate dehydrogenase (GDH) in Y. lipolytica. The aims of this study were to test gene complementation in S. cerevisiae and to analyze the phenotype of gene deletion in Y. lipolytica. The NADPH‐GDH gene in Y. lipolytica (ylGDH1/3) was identified by homology to NADPH‐dependent GDHs in S. cerevisiae (scGDH1 and scGDH3). For the complementation test, the ylGDH1/3 was amplified by PCR, cloned into the S. cerevisiae pBEVY‐L vector under control of the constitutive GPD/ADH1 promoter and verified by restriction digests and sequencing. The pBEVY‐L‐ylGDH1/3 was introduced into a S. cerevisiae null mutant strain that lacks any GDH activity. The subsequent gain of GDH activity to a level greater than that in wild type demonstrated the NADPH‐dependent GDH activity of the protein encoded by ylGDH1/3. For gene disruption in Y. lipolytica, overlap extension PCR was used to create a ylGDH1/3 disruption cassette containing the selection marker LEU2 (gdh1/3::LEU2) from Y. lipolytica. The cassette was transformed into Y. lipolytica forming a mutant strain via homologous recombination. PCR analysis confirmed the disruption and enzyme activity measurements indicate a significant decrease in NADPH‐dependent GDH activity in the knockout strain, which further suggests that ylGDH1/3 in Y. lipolytica encodes NADPH dependent GDH. Future investigations include examining how the NADH dependent GDH activity is affected in the mutant strain. This valuable information about the yeast's metabolism may further aid researchers in understanding the metabolic pathways, as well as using Y. lipolytica as a model to learn more about metabolic diseases such as diabetes and obesity.


Contamination of cows and heifers by Toxoplasma gondii and Coccidia spp. using serological and coproscopic methods is studied. 13,3 % of samples contain antibodies to antigen Toxoplasma gondii and 22,5 % of animals are infected by Eimeria spp. and Cryptosporidia spp


Dispersed generators such as wind power systems, photovoltaic systems, and cogeneration systems are expected to mitigate the environmental burden of energy consumption, and their installation has been promoted recently. Micro‐Grid is focused on as a method to solve some problems in a commercial electric power line when installing a large number of dispersed generators, and some demonstrative research on Micro‐Grid for large‐scale systems is being carried out now. Also, small cogeneration systems for houses, such as gas engines and fuel cells, are expected to improve CO2 emissions. However, if the power and heat demand of a family are relatively small or are unbalanced, the cogeneration system does not operate effectively. The authors have studied the application of Micro‐Grid for home energy supply, and have developed a control system to solve this problem. The system achieves a reduction of CO2 emissions and energy costs by sharing electric power and heat among some houses with cogeneration systems. This paper presents an outline of the newly developed system, and in particular describes the effect of the reduction in CO2 emissions compared with a conventional energy supply method, and the case in which dispersed generators are installed in some houses and operate independently. © 2009 Wiley Periodicals, Inc. Electr Eng Jpn, 170(3): 19–27, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20879


Three new transition metal complexes with Schiff base of salicylaldehyde-cystine(H2Cys-sal) [Cu(Cys-sal),Co(Cys-sal),Mn(Cys-sal) were synthesized.The composition and structure of the products were analyzed by means of ultraviolet spectrometry,infrared spectrometry,elemental analysis,and molar conductance test.The fluorescent characteristics of the complexes were evaluated with a fluorescence spectrometer.The antibacterial activity of the products was evaluated by conducting biological activity tests.It was found that the three kinds of complexes were all able to strongly quench the fluorescence of bovine serum albumin(BSA).Besides,they were able to inhibit staphylococcus aureus,escherichia coli,bacillus subtilis,and pseudomonas aeruginosa to varied extents.


Lipid nanoparticles, including nanoemulsions (NEs) and nanostructured lipid carriers (NLCs) are colloidal carriers with a lipid matrix that is solid at body temperature. These colloidal carriers have attracted increasing interest for their use in therapeutic and cosmetic applications. The performance of lipid nanoparticle formulations is greatly influenced by their composition and structure. Lipid nanoparticles are generally composed of lipids, surfactants and co-surfactants. The lipid materials used in the production of lipid nanoparticles are usually solid at room temperature. Being well-tolerated in physiological conditions, lipid nanoparticles are typically biocompatible. Liquid lipids, or oils, are specifically used for production of NLCs. In most cases, lipid nanoparticles are produced as dispersions and surface-tailored with surfactants to improve dispersion stability. It was shown that NLCs reveal some advantages for drug therapy over conventional carriers, including increased solubility, the ability to enhance storage stability, improved permeability and bioavailability, reduced adverse effect, prolonged half-life, and tissue-targeted delivery.


Objective:To explore expressions of platelet activator combined-1(PAC-1) and P-selectin(CD62p) in patients with acute cerebral infarction(ACI) at different degrees.Methods:Totally 287 patients with ACI from October 2008 to October 2011 were divided into lacunar infarction group(n=76),small volume ACI group(n=125) and large volume ACI group(n=86);50 health volunteer were served as control group.Levels of PAC-1 and CD62p were detected by flow cytometry.Results:Levels of PAC-1 and CD62p were increased in ACI group(46.9 mg/L,28.4 ng/L) than in control group(29.6 mg/L,10.3 ng/L)with significant differences(t=2.042,P=0.044;t=2.137,P=0.038).Levels of PAC-1 and CD62p were significantly different among three groups(F=7.32,P=0.046;F=5.38,P=0.043).Levels of PAC-1 and CD62p were significantly different between small volume ACI group(39.9 mg/L,24.5 ng/L) and lacunar infarction group(45.9 mg/L,29.1 ng/L)(SNK-q=4.417,4.129;P=0.031,0.037).Levels of PAC-1 and CD62p were significantly different between large volume ACI group(53.9 mg/L,33.8 ng/L) and small volume ACI group and lacunar infarction group(SNK-q=4.216,4.022;P=0.039,0.042).Conclusions:Significant expressions of PAC-1 and CD62p in patients with ACI can be used to detect the degrees of ACI and are of great importance in preventing and monitoring diseases development.


Constructing a harmonious society on the foundation of socialist market economy is a main task in the realization of Chinese modernization. Government plays a critical role in the development of socialist harmonious society. Market economy is credit economy and economy restricted by legal system. Government credibility is not only the foundation of credit but also guarantee of economy restricted by legal system. Therefore, this article concludes that government credibility is the foundation of the harmonious development of socialist market economy.


Some experts believe that physicians overadmit patients with community-acquired pneumonia (CAP). The Pneumonia Severity Index, often referred to as the


Objective To discuss the clinical value of precut sphincterotomy in ERCP.Methods The cases who cound not undergo stand-ard sphincterotomy were treated by needle-knife precut,plow-knife precut and transpancreatic duct precut.Results 58 cases underwent precutsphincterotomy,of which,53 were suceessful(91.3%).3 with palilla bleeding were treated by electric congeal and spraying adrenalin.2 with mildpancreatitis were improved by conservative treatment.Conclusion Precut sphincterotompy is recommendable to be an adjunctive therapeutic tech-nique in routine ERCP and ESTfor its effect on improving the success of ERCP.


Information technology (IT) stands as a cornerstone in the contemporary landscape of national development. Its significance is pervasive, touching every facet of society, economy, and governance. This comprehensive article embarks on an extensive exploration of the multifaceted role of information technology in shaping the trajectory of a country's progress. Through an intricate interplay of technological advancements, policy considerations, challenges, and opportunities, IT emerges as a linchpin in the journey towards sustainable development.


The paper reveals Azerbaijan's reaction to the crisis in Ukraine. The author proposes to view the events in Ukraine not as much in the context of the national position and the regional politics, as in the context of the global geopolitics. To this end paper studies new geopolitical realities being shaped, and comes to the conclusion about "global multipolar regionalism" currently unfolding and EU's "post-industrial institutional colonialism". Taking into account the need for drawing lessons from the crisis, the author offers possible geopolitical alternatives for Azerbaijan.


– We study antiferromagnetism and single-particle properties in the two-dimensional half-filled Hubbard model at low temperature. Collective spin fluctuations are governed by a non-linear sigma model that we derive from the Hubbard model for any value of the Coulomb repulsion. As the Coulomb repulsion increases, the ground state progressively evolves from a Slater to a Mott-Heisenberg antiferromagnet. At finite temperature, we find a metal-insulator transition between a pseudogap phase at weak coupling and a Mott-Hubbard insulator at strong coupling. Introduction. – The Hubbard model [1] and its generalizations play a key role in the description of strongly correlated fermion systems such as high-Tc superconductors, heavy fermions systems, or organic conductors [2]. Despite its simplicity (the model is defined by two parameters, the inter-site hopping amplitude t and the local Coulomb interaction U , and the symmetry of the lattice), exact solutions or well-controlled approximations exist only in a few special cases as in one-dimension (1D) or in the limit of infinite dimension [1]. It is now well established that the ground state of the 2D half-filled Hubbard model on a square lattice has antiferromagnetic (AF) long-range order. The origin of antiferromagnetism is believed to depend on the strength of the Coulomb repulsion. At weak coupling (U t), a Fermi surface instability gives rise to an insulating spin-density-wave ground state as first suggested by Slater [3]. In 2D, thermal (classical) fluctuations preclude a finite-temperature transition (Mermin-Wagner theorem) and the phase transition occurs at TN = 0. Since the fermion spectral function is gapped at T = 0, one expects, from a continuity argument, that it will exhibit a pseudogap at finite temperature as a result of strong AF fluctuations [4]. At strong coupling (U t), the system becomes a Mott-Hubbard insulator below a temperature of the order of U . The resulting local moments develop AF short-range order at a much smaller temperature (∼ J = 4t/U), and AF long-range order sets in at TN = 0. Although the Hartree-Fock (HF) theory gives a reasonable description of the AF ground state, it fails in 2D since it predicts AF long-range order. Several alternative approaches, which do satisfy the Mermin-Wagner theorem, have been proposed: Moriya's self-consistent


Life and work both look on "safe environment" as precondition. Whether it is from a historical perspective or from a practical point of view, safety would be seen as the first guarantee of human existence. Due to this great significance, Chinese ancestors attached great importance to the building of "safety" theory. Through reading the "Book of Changes" carefully, we not only can find out ancestors' desire for safety, but also can learn wisdom from it and take advantage of it to help build a contemporary "safe society".


A bit-error-rate (BER)-based physical layer security approach is proposed for the finite blocklengths. For secure communication in the sense of high BER, the information-theoretic strong converse is combined with cryptographic error amplification achieved by the substitution permutation networks based on the confusion and diffusion. For the discrete memoryless channels (DMCs), an analytical framework is provided showing the tradeoffs among the finite blocklength, the maximum/minimum possible transmission rates, and the BER requirements for the legitimate receiver and the eavesdropper. In addition, the security gap is analytically studied for the Gaussian channels and the concept is extended to other DMCs including the binary symmetric channels and binary erasure channels.


The study investigates the acquisition of English verb placement by L1 Arabic speakers of L2 English which is generally taken to constitute a UG parameter often referred to as the verb movement parameter. It sets out to test two competing hypotheses namely, the Failed Functional Features
Hypothesis (FFFH) (Hawkins and Chan, 1997) and the Full Transfer Full Access Hypothesis (FTFAH) (Schwartz and Sprouse 1994; 1996). The FFFH view holds that post-childhood L2 adult learners are unable to reset parameters from their L1 values to the L2 settings where these differ from the L1 settings (due to the partial inaccessibility of UG). On the other hand,the FTFAH claims that post-childhood L2 adult learners start out with the
parameter settings instantiated in their L1 grammars (full transfer) and that they can subsequently reset parameters to the target L2 settings where these differ from the L1 settings (due to the full accessibility of UG). Altogether
240 L1 Arabic speakers of L2 English who were subdivided into three proficiency levels (lower-intermediate, upper-intermediate and advanced) participated in the study. A grammaticality judgement task on verb placement was designed to test the learners' underlying knowledge of three
of the properties subsumed under the verb movement parameter in English: negation in both finite and non-finite contexts, adverb placement and floating subject quantifier placement in finite contexts, with thematic verbs, be auxiliary and copula be verb forms. The findings of the study provide evidence in support of the FFFH.


Applied planning of land is a process in which the method of using land and the local – spatial diffraction pattern of land uses will be determined in order to provide welfare in the social life. The land use includes investigating the method of land use proportional to different activities such as health care, residential, administrative and commercial activities. The rural economy surrounds physical aspects of rural residents and includes all economic activities which meet their physical needs. In this article, we study the effect of land use changes due to the rural development on the rural economy. In the current research, we used a descriptive analytical method and the method of data collection was a combination of documentary and case studies. The research results indicate that land use changes have both positive and negative effects on rural residents' lives. Land use changes in rural areas under study have mainly occurred in agricultural areas of the rural context and passages and main roads; so, they will destroy potential agricultural lands and consequently negative economic effects will appear. However, land owners' satisfaction of the land change due to obtaining an economic interest more than the economic interest resulted from agriculture is considerable. Therefore, some solutions are proposed for maintaining rural residents' satisfaction of the land use change in order to partly reduce its negative economic effects. [Mohammad Bagher Ebrahimi and Hossein Rahimi. Study of Economic Effects of Land Use Changes in Rural Areas Due to the Rural Development(Case Study: Surrounding Rural Areas of Rasht Metropolis). J Am Sci 2013;9(6s):122-127]. (ISSN: 1545-1003). http://www.jofamericanscience.org. 18


We study the long-term and dynamic relationship between de jure and de facto judicial independence using a large panel dataset covering up to 87 countries and as many as 61 years. In line with the prevailing theoretical view in the literature, our analysis shows a positive relationship between these variables. However, the magnitude of the relationship is quite small. The positive relationship between the two variables is primarily driven by non-OECD countries.


The low‐temperature oxidation of propane was investigated using a jet‐stirred reactor at atmospheric pressure and two methods of analysis: gas chromatography and synchrotron vacuum ultraviolet photoionization mass spectrometry (SVUV‐PIMS) with direct sampling through a molecular jet. The second method allowed the identification of products, such as molecules with hydroperoxy functions, which are not stable enough to be detected by gas chromatography. Mole fractions of the reactants and reaction products were measured as a function of the temperature (530–730 K), with a particular attention to reaction products involved in the low temperature oxidation, such as cyclic ethers, aldehydes, alcohols, ketones, and hydroperoxides. A new model has been obtained from an automatically generated one, which was used as a starting point, with a large number of re‐estimated thermochemical and kinetic data. The kinetic data of the most sensitive reactions, i.e., isomerizations of alkylperoxy radicals and the subsequent decompositions, have been calculated at the CBS‐QB3 level of theory. The model allows a satisfactory prediction of the experimental data. A flow rate analysis has allowed highlighting the important reaction channels. Corresponding author: Olivier HERBINET Laboratoire Réactions et Génie des Procédés Ecole Nationale Supérieure des Industries Chimiques BP 20451, 1 rue Grandville, 54000 Nancy, France Tel: +33 (0)3 83 17 53 60 Fax: +33 (0)3 83 17 81 20 E‐mail: olivier.herbinet@univ‐lorraine.fr


Background: Chronic hypersecretion of the pancreatic hormone amylin leads to infiltration of oligomeric amylin in cellular membranes, which contributes to β-cell dysfunction and type-2 diabetes (T2D). We recently showed that oligomeric amylin also accumulates in myocardium of patients with obesity or T2D. Hypothesis: Oligomeric amylin may infiltrate the sarcolemma exposing membrane lipids to peroxidation by ROS, thus exacerbating myocardial oxidative stress. Methods: We investigated the relationship between incorporated amylin and lipid peroxidation in ventricular myocytes from obese patients (BMI≥30) with heart failure (HF) (O-HF group; N=6), obese humans without HF (O-NF group; N=6) and healthy people with BMI Results: Compared to L-NF controls, the myocyte level of amylin is increased in both O-HF group (10-fold; P 11 -BODIPY and Liperfluo indicates increased lipid peroxidation in HIP rat myocytes (2-fold; P Conclusions: Together, these findings support the hypothesis that circulating oligomeric amylin infiltrates cardiac myocytes in humans and exacerbates lipid peroxidation. Strategies to mitigate myocardial deposition of amylin should be pursued.


Background and Objectives  The Public Health Programme (Directorate General Sanco) gave impetus to the need for equivalent recognition of inspections of blood establishments among European Member States (MS) through the development and implementation of commonly accepted criteria and standards by funding the European Blood Inspection Project (EuBIS) (HYPERLINK "http://www.eubis‐europe.eu"http://www.eubis‐europe.eu). EuBIS is a collaborative effort of 27 representatives from 19 MS, including governmental institutions, blood establishments and competent authorities. It has cooperative working partnerships with five organisations, three projects, and is supported by the European Blood Alliance (EBA).


Background: Helicobacter pylori infection is an important triggering agent for development of gastric malignancies, peptic ulcer disease and other dyspeptic symptoms. Therefore a crucial part in the management of infection is a fast and accurate diagnostic technique which would give reliable results in detecting infection in symptomatic patients. Aim: This study aimed to compare and evaluate the reliability of molecular technique over conventional culture method for early diagnosis of H. pylori infection in dyspeptic patients. Materials and Methods: A cross sectional hospital-based study was conducted between June 2016 and May 2017 and included 100 gastric biopsy specimens from clinically suspected dyspeptic patients undergoing routine upper gastrointestinal tract endoscopy. These specimens were analyzed using the conventional culture method as well as molecular technique (PCR assay) for species identification and virulent factor determination directly from biopsy specimens. Results: The molecular method could detect H. pylori in 44% cases with detection virulent cagA and vacA genes, whereas the culture method could detect 20% cases. Moreover the turnaround time taken by molecular method was 24-36 Hours whereas that of the culture method was 5-6 days. Conclusion: The molecular method can be considered as a more sensitive as well as rapid method for detection of H. pylori from biopsy specimens which can be used routinely for diagnosis of H. pylori infection.


After a short review of results which we recently obtained on deformations of Lie algebras associated with symplectic manifolds, we discuss physical applications and treat some examples with deformed Poisson brackets. We make explicit a connection between classical and quantum mechanics, and the theory of Dirac brackets for second class constraints, from the viewpoint of deformation theory. Finally we discuss the general Dirac constraints formalism.


Single-thread performance has not improved much over the past few years, despite an ever increasing transistor budget. One of the reasons for this is that there is a speed gap between the processor and main memory, known as the memory wall. A promising method to overcome this memory wall is aggressive out-of-order execution by extensively enlarging the instruction window resources to exploit memory-level parallelism (MLP). However, simply enlarging the window resources lengthens the clock cycle time. Although pipelining the resources solves this problem, it in turn prevents instruction-level parallelism (ILP) from being exploited because issuing instructions requires multiple clock cycles. This paper proposed a dynamic scheme that adaptively resizes the instruction window based on the predicted available parallelism, either ILP or MLP. Specifically, if the scheme predicts that MLP is available during execution, the instruction window is enlarged and the window resources are pipelined, thereby exploitingMLP. Conversely, if the scheme predicts that less MLP is available, that is, ILP is exploitable for improved performance, the instruction window is shrunk and the window resources are de-pipelined, thereby exploiting ILP. Our evaluation results using the SPEC2006 benchmark programs show that the proposed scheme achieves nearly the best performance possible with fixed-size resources. On average, our scheme realizes a performance improvement of 21% over that of a conventional processor, with additional cost of only 6% of the area of the conventional processor core or 3% of that of the entire processor chip. The evaluation results also show 8% better energy efficiency in terms of 1/EDP (energy-delay product). key words: microprocessor, superscalar processor, memory-level parallelism, instruction-level parallelism


Cerebral blood flow, hemodynamics and metabolism in patients receiving ECMO therapy were assessed by combined TCD and frequency-domain NIRS, with a goal to understand the risks of neurologic injuries associated with ECMO-related factors.


From the air stream flowing through the application region of the coating system, in order to separate the overspray of the liquid coating material, overspray in the air stream is charged in particulate auxiliary material which is introduced into the air stream. Fresh auxiliary materials, through the tube arrangement (12), from a supply container (10), is conveyed the arrangement containers located in the region of the gas flow beneath the application region to (14). .FIELD 1


This paper describes the development and validation of a novel web-based interface for the gathering of feedback from building occupants about their environmental discomfort including signs of Sick Building Syndrome (SBS). The gathering of such feedback may enable better targeting of environmental discomfort down to the individual as well as the early detection and subsequently resolution by building services of more complex issues such as SBS. The occupant's discomfort is interpreted and converted to air-conditioning system set points using Fuzzy Logic. Experimental results from a multi-zone air-conditioning test rig have been included in this paper.Copyright © 2004 by ASME


It is a commonplace in the study of pre-Han texts to acknowledge that the received version of a given text cannot be assumed to reflect with any significant degree of fidelity its original form. A text is, as the literal sense of the English word implies, something woven, something stitched together (cf. Skt. sūtra, Ch. ching), and once woven, it may ravel. It would then be subject to re-weaving, either in its entirety alone, or together with other, originally distinct texts. In the former case individual phrases or lines might be introduced throughout the piece for reasons for euphony, stylistic balance, or perhaps because of a misunderstanding of the original sense on the part of a later scribe. In the latter case wholly independent accounts might become interwoven, begetting a new, hybrid document. Such re-weaving with its gratuitous additions of new material might occur several times, further distorting the primary content on each occurrence. The end result of such a process of textual alterations would be a composite and thoroughly heterogeneous work of diverse provenances, and of uncertain internal uniformity.


A meeting of the Bureau of the History Division of the USSR Academy of Sciences was held on February 10 of this year. It heard and discussed papers by Academician I. I. Mints and Corresponding Academician M. P. Kim devoted to current problems in the Marxist-Leninist concept of socialist revolution. Discussion of the papers was participated in by members of the History Division as well as specialists invited from related institutes of the Academy, the Institute of Marxism-Leninism, the Social Science Academy of the Central Committee of the CPSU, and other institutions.


Actinic keratosis in the most common premalignant keratotic tumour of sun‐exposed skin. A 66‐year‐old man developed a large actinic keratosis on his scalp, which did not respond to conventional treatment. Fractionated radiotherapy with a cumulative dose of 28 Gy resulted in complete remission without relapse during a 14‐month follow‐up. In older subjects in whom conventional treatment fails, low‐dose fractionated radiation therapy is an effective alternative method.


A match was made between consensual indexes of elementary education goal priorities and the availability of published tests that held promise for their assessment. A Q sort was utilized to obtain priority ratings on 106 pre-established goals from a nationwide sample. Independently, published tests for the elementary level were sorted into the same 106 goal categories. Results of the matching techniques indicated that most goals, whether high or low in priority, are measured by few or no published tests. This failure on the part of test publishers to respond to the needs of education is seen as an important contributor to the current popularity of criterion-referenced instruments.


Ly Son is a small but important archipelago of Vietnam. It contains different ecosystems ranging from urbanized to natural vegetation. However, little was known about bats and the general biodiversity of this archipelago. In August 2017 and May 2022, the author conducted a series of bat surveys throughout the archipelago. Bats were captured using mist nets and harp traps. Echolocation calls were recorded using the PCTape system at every netting and trapping site and inside a flight tent. Recorded calls were analyzed using the Selena software. Results from the survey confirmed that the Ly Son archipelago is home to two bat species belonging to two genera, two families: Pteropodidae (Cynopterus sphinx) and Vespertilionidae (Myotis muricola). Of these two species, C. sphinx was very common while M. muricola was rarely recorded in the archipelago. Remarkably, the echolocation signal duration of M. muricola is in a range of 2.6-5.2 milliseconds which is longer than descriptions in previous publications.


In this paper, we present FAIMUSS a tool for data transformation from a wide variety of heterogeneous streaming and archival sources to RDF. This is a typical situation in the analysis of mobility data, such as maritime and aviation, where streaming position data of moving objects need to be associated with static information (such as crossing sectors, protected geographical areas, weather, etc.) in order to provide semantically enriched trajectories. FAIMUSS is designed to perform "near-to-the-sources" integration, by interaction between a streaming source and an archival source, thus generating linked RDF graph fragments. Most of the existing approaches operate either on streaming or on static sources, thus fail to address our problem setting. In addition, FAIMUSS supports reusable user-defined functions that are applied to input data and achieve the desired data transformations and cleaning. We demonstrate our prototype by using data from the maritime and aviation domains.


Infantile social attachment to the parent or parent-surrogate as a process of learning within a specific period of the infant animal's life was first reported in the early 1870's by the Scottish behaviorist, Douglas Spalding (1873). Laboratory investigations of this phenomenon, now generically called imprinting, invariably have used artificial models as surrogates and the following response of the young as an index of both readiness to imprint and retention of imprinting (cf. Gray, 1958). Writers have frequently considered the following response itself as learned (Verplanck, 1958), as reinforcing (Thorpe, 1957 ) , or even as a source of an afferent feedback positively related to degree of imprinting (Hess, 1959). This unilateral emphasis on following, which Spalding thought of as an unlearned response, has tended to divert attention from a more general operational definition of imprinting: an acquired ability to discriminate the object to which the young animal has been sufficiently exposed at a critical age. The principal aim of this experiment was to separate the following response from this acquired ability to discriminate. The method was designed to give the infant animal visual experience with a parent-surrogate, but to prevent overt following or any form of contact response. W e neither prevented nor measured the orienting response which necessarily is the first part of the following response, since orienting is presumably integral to any kind of learning in such a situation. The specific question was whether a chick will form an attachment, expressible as a discrimination, without overt following or any other independently specifiable reinforcement or drive reduction.


ABSTRACT Entomopathogenic nematodes (EPN) are well-established plant protection tools for the control of insect pests. The release of EPN species is often limited to species that are endemic in the country. Therefore, surveys to check for the presence of EPN species in the country are necessary. Here, a sampling and baiting method based on the in situ attraction of EPN to insects contained in a plastic tube is described. Heterorhabditis downesi was isolated from overgrown dunes at the Baltic coast and Steinernema feltiae from chromic luvisol further inland. This is the first report of the presence of H. downesi in Germany.


Cytotoxic T lymphocytes (CTLs) are involved in development of diabetes. However, the impact of excessive glucose on CTL-mediated antigen-independent killing remains elusive. Here, we report that TNF-related apoptosis inducing ligand (TRAIL) is substantially up- regulated in CTLs in environments with high glucose (HG) both in vitro and in vivo. The PI3K- Akt-NFκB axis and non-mitochondrial reactive oxygen species are essential in HG-induced TRAIL upregulation in CTLs. TRAILhigh CTLs induce apoptosis of pancreatic beta cell line 1.4E7. Metformin and Vitamin D synergistically reduce HG-enhanced expression of TRAIL in CTLs and coherently protect 1.4E7 cells from TRAIL-mediated apoptosis. Notably, in patients with diabetes, correlation between Vitamin D concentrations in plasma and glucose levels is linked to HG-enhanced TRAIL expression on CTLs. Microarray data reveal that OXCT2, an important enzyme in ketone body catabolism, is a promising target in response to vitamin D. Our work not only reveals a novel mechanism of CTL involvement in progression of diabetes, but also establishes CTLs as a target for combined metformin and vitamin D therapy to protect pancreatic beta cells of diabetic patients.


In sending copies of Dr. Henrietta M. Larson's Jay Cooke—Private Banker to its members, the Business Historical Society has taken a definite step forward. For the first time in its eleven years' existence, the Society has, with this presentation, been instrumental in distributing a significant historical volume prepared by a trained business historian and dealing with the business career of an important business man.


Watermelon (Citrullus vulgaris L.) is a summer fruit typical to help fatigue systemic absorption is getting better. The goal of this study is to screen antioxidant activity to ensure the possibility as a functional material for exocarp of watermelon. Watermelon was extracted with 70% methanol, 70% ethanol, chloroform: methanol (CM, 2:1, v/v). Total phenol contents were 12.01 mg/g, 8.89 mg/g, 3.53 mg/g in the 70% methanol, 70% ethanol, CM, in that order, respectively. Total flavonoid content, DPPH radical scavenging activity, ABTS radical scavenging activity, ferric reducing antioxidant power (FRAP), β-carotene bleaching assay were 70% methanol extract remarkably higher than the other extracts. And these results showed the same trend of total phenol content. From the above results shows that watermelon was effective on the antioxidative activity.


Biochemistry exhibits an intense dependence on metals. Here we show that during dry-down reactions, zinc and a few other transition metals increase the yield of long histidine-containing depsipeptides, which contain both ester and amide linkages. Our results suggest that interactions of proto-peptides with metal ions influenced early chemical evolution.


Rheumatoid arthritis (RA) is an aggressive immune-mediated joint disease characterized by synovial proliferation and inflammation, cartilage destruction, and joint destruction1. Despite efforts to characterize the disease subsets and to predict the differential prognosis in RA patients, disease heterogeneity is not adequately translated into the current clinical subclassification2.To develop and validate an integrative system approach for stratifying patients with RA according to disease status and whole-genome gene expression data.An RNA sequencing dataset of synovial tissues from 124 RA patients (including 57 patients with early RA, 95 with established RA) and 15 healthy controls (HC) was imported from the Gene Expression Omnibus (GEO) database (GSE89408) by software package R (version 4.0.3). After filtrating of differentially expressed genes (DEGs) between RA and HC, non-negative matrix factorization, functional enrichment, and immune cell infiltration were applied to illustrate the landscapes of these patients for classification. Clinical features (age, gender, and auto-antibodies) were also compared to discover the signatures of these classifications.A matrix of 576 DEGs from RA samples was classified into 5 subtypes (early/C1–C3, established/C4-C5) with distinct molecular and cellular signatures and two sub-groups (S1 and S2) (Figure 1A-1D). New-onset patients (early C2) and established C4 patients were named as S1, they shared similar gene signatures mainly characterized by prominent immune cells and proinflammatory signatures, and enriched in the chemokine-mediated signaling pathway, lymphocyte activation, response to bacterium and Primary immunodeficiency. S2(C1, C3 and C5) were more occupied by synovial fibroblasts of destructive phenotype. They were mainly enriched in the response to external factors and PPAR signaling pathway (Figure 1E-1H). Interestingly, combined with clinical information, S1 and S2 had no significance in age and gender (P > 0.05). But patients in S1 had a stronger association with the presence of anti-citrullinated protein antibodies (ACPA) (P < 0.05) (Figure 1I-1J).We successfully deconvoluted RA synovial tissues into pathobiological discrete subsets using an unsupervised machine learning method and described their distinct molecular and cellular characteristics. These results provide important insights into divergent and shared mechanistic features of RA and serve as a template for future studies to guide drug tar-get discovery by synovial molecular signatures and de-sign stratified approaches for patients with RA.[1]Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet 2016;388(10055):2023-38. doi: 10.1016/S0140-6736(16)30173-8 [published Online First: 2016/10/30][2]Jung SM, Park KS, Kim KJ. Deep phenotyping of synovial molecular signatures by integrative systems analysis in rheumatoid arthritis. Rheumatology (Oxford) 2020 doi: 10.1093/rheumatology/keaa751 [published Online First: 2020/11/25]This project was supported by National Science Foundation of China (82001740), Open Fund from the Key Laboratory of Cellular Physiology (Shanxi Medical University) (KLCP2019) and Innovation Plan for Postgraduate Education in Shanxi Province (2020BY078).None declared


This segment of my web pages is devoted to various sets of notes on different aspects of the theory of frames. For convenience I call each such set of notes a part. Thus the long term project is to write several parts which as a whole give an account of a decent proportion of frame theory. At the time of writing the project is not finished. Several parts have been written and released. Other parts are nearly finished and, the devil willing, will be released quite soon. Other parts are still tentative. A list of these parts with their current status is given in Table 1. Other parts may be added in due course. Each part may, is, and will be written separately without worrying too much about the contents of the other parts. Thus there may be some overlap between certain parts. More importantly, I may have omitted some information, this having slipped through a crack between two parts. To make sure that the whole collection of parts is watertight does need quite a bit of intelligent design, and that would take the best part of a week to organize. The moral of this story is that you should keep an eye on this Overview. It may change quite a lot as I make more parts available or correct and amend earlier parts. At the head of each part, and this Overview, you will find a banner.


Abstract: At present, thetoll roadhas an important role to serve traffic flow, especiallyin regionsuch asNusaDua.At this time, has not been knowncharacteristics ofvehiclearrivalandserviceoftoll gate. The objectives of this study are: to analyze the characteristics of vehicle arrival rate, to analyze the characteristics of service level toll gate, to analyze the performance of services toll gate and in order to analyze the optimal number of toll gate according to the arrival rate of vehicles at the entrance to the toll road Bali Mandara. Results of analysis showed thatthe characteristics ofvehicle arrivalin cashtoll gateandelectronictoll gatefollowedPoissondistribution. Characteristicstoll gate1, toll gate2andtoll gate3 had a negativeexponentialdistribution. Performance of cashtoll gateservice systemswithdisciplineFVFSqueuewas: =1,131vehicles/min, =0,230vehicles/min, =0,128, and =0,026min. Performanceof electronictoll gateservice systemwithFIFOqueuingdiscipline was: =0,000923vehicles/min, =0,000001vehicles/min, =0,001668minutes, and =0,000002minutes. The results ofthegeneralisedcost analysisforcashtoll gate showedthat optimalconditions for existing vehicle arrivals can be achievedif onlyone toll gate was opened.


Air-filled Substrate Integrated Waveguide (SIW) based on multilayer Printed Circuit Board (PCB) process is studied in this paper for millimeter-wave applications. To allow interconnects of the proposed Air-filled SIW with Substrate Integrated Waveguide (SIW), a wideband transition is needed. This paper presents an assessment of transition of dielectric SIW toward an air-filled SIW with various design shapes of taper in order to evaluate the losses in the structure. The shape of taper is designed accordingly to the equation for taper consisting of linear, exponential, raised cosine and parabolic. At Ka-band it is shown that raised cosine taper based on Rogers RT/Duroid 6002 has a better return loss lower than 20 dB, with transmission loss of 0.16±0.02 dB from 28 to 40 GHz. For the U-band, the raised cosine taper based on Rogers RT/Duroid 6002 also has a better return loss lower than 40 dB and the transmission loss is 0.3±0.01 dB from 44 to 60 GHz, respectively. For validation purposes, a back-to-back transition is simulated. It achieves a return loss of better than 20dB and a transmission loss of 0.35±0.05dB from 28 to 40 GHz. Then, a return loss of better than 40 dB and transmission loss of 0.75±0.05dB from 44 to 60 GHz.


The paper by Naipal et al is a quite interesting study on the implementation of erosion schemes to Earth system models. This an hot topic and this study is a significant contribution to existing literature. In particular, it provides a very flexible approach that can be adapted to any ESM. I believe that after some revisions the paper can be published. I have some comments detailed below that I hope will be helpful to improve the paper.


The study was conducted to investigate the impact of emotional intelligence and creativity among the university students. The research method in this study is the correlation type. The aim of the correlation study was understands the complex patterns of behavior by studying the correlation between the models and variables. In this study statistical population was 2500 persons of the students in various disciplines of the humanities; 100 subjects were selected using the Morgan table and tests were conducted on them. Pearson correlation coefficient was used to hypothesis testing and study the relationship between emotional intelligence and creativity in between the humanities students. Also t statistical method was used to change the independent to testing the second and third hypothesis includes creativity and emotional intelligence. Results showed that there was a significant relationship between creativity and emotional intelligence (correlation coefficient = 0.628; validated t for correlation coefficient = 4.271; the table t = 3.861; with 98 degrees of freedom and 5% significant level). Also in current study research hypothesis was not confirmed and there was no significant difference between male and female students in terms of creativity and emotional intelligence. KEY WORD: Creativity, emotional intelligence, humanities, students


This paper investigates the potential behavior, both good and bad, of the well-known BFGS algorithm for smooth minimization, when applied to nonsmooth functions. We consider three very particular examples. We first present a simple nonsmooth example, illustrating how BFGS (in this case with an exact line search) typically succeeds despite nonsmoothness. We then study, computationally, the behavior of the BFGS method with an inexact line search on the same example, and discuss the results. In further support of the heuristic effectiveness of BFGS despite nonsmoothness, we prove that, for the very simplest class of nonsmooth functions (maximums of two affine functions), the method cannot stall at a nonstationary point. On the other hand, we present a nonsmooth example where the inexact-line-search BFGS method converges to a point despite the presence of directions of linear descent. Finally, we briefly compare line-search and trust-region strategies for BFGS in the nonsmooth case.


This article presents a computational modelling approach for negative effects simulation of visual distraction while driving. In order to investigate these effects, an experiment was implemented on a driving simulator. Empirical data collected shows that visual distraction impacts the driving performance at perceptive and behavioural levels. The aim of this study was also to investigate and to simulate the distractive effects on driver's mental models. Indeed, driving decisions and behaviours are based on a temporal-spatial mental model, corresponding to the driver's situational awareness (SA). In case of visual distraction requiring off-road glance, mental model updating may be imperfectly done and driver's actions are thus based can differ on the situational reality. From these, a perception module, interfaced with cognitive functions of a computational model named COgnitive Simulation MOdel of the DRIVEr, was developed and implemented for simulating visual distraction effects and human errors risks at perceptive, cognitive and behavioural levels.


OBJECTIVE: To provide reference for the development of drug retail trading. METHODS: The distribution of retail drugstores and the causes of irrational distribution were summarized and analyzed with comparison method. The experiences of Europe and America about distribution management of retail drugstores were interpreted, and some suggestions were put forward for reasonable distribution of retail drugstores in China. RESULTS CONCLUSIONS: The number of retail drugstores has increased by 20 000 per year in China during 2006-2009, while increased by 2 001 during Jan.-Jun. 2012. The distribution of retail drugstores are quite uneven. The irrational reasons of retail drugstores in China are the poor actual effect and the lack of legitimacy of the distance adjustment method, the poor operability and flexibility of the population density adjustment method, and the market regulation method's uncontrollability and lagging. The systems to set up drugstores are different among member states of Europe; in some countries, geography and population distribution are regarded as the standard; in other countries, the establishment of drugstores is adjusted according to license system. Retail drugstores are supervised and managed by state board of directors in America. The retail drugstores' distribution should abide by market regulation first and government intervention second in our country. It also should improve the supervision and management of drug retail market.


Drawing on a series of cases that Hermès has litigated in China, the chapter discusses how transnational companies should tap into the potential of non-traditional trademarks to promote their businesses in China. Section I of the chapter provides an overview of the most important requirements for registering such trademarks in China. It considers why the Chinese courts rejected Hermès' bid to register the shape of its Kelly bag as a three-dimensional trademark in China. Through the lens of several trademark cases that the French high-fashion luxury brand litigated in China, Sections II and III offer nuanced analysis of how companies can protect their trademarks in the Chinese first-to-file registration system and how to determine the well-known-trademark status in the country. Sections IV and V further examine the lessons that can be learnt from the Hermès cases about securing anti-confusion and anti-dilution protection of non-traditional trademarks in China.


Theoretical, methodological and applied aspects of creating a database (DB) of long-term retrospective information about the yield of grain crops are considered. The database is designed for statistical processing and modeling of multi-year data. Statistical information on annual levels of grain yield is the basis for planning, forecasting, management and optimization of agricultural production. To implement these tasks and their information support, we use design methods and models that allow us to build relational databases that provide statistical and neural network modeling of interannual variability of yield levels. The data storage format (*.csv) is justified, which provides in-depth processing and statistical analysis using built-in Python libraries. The review statistical analysis of productivity on the example of grain crops grouped by annual intervals is presented, and their features are revealed.


Primarily focused on recent trends in Western Europe, this article examines a range of activities that fall under the term "far right". It problematizes this umbrella term before surveying recent developments in the diverse range of political parties, from the United Kingdom Independence Party to Jobbik, identifying a broad trend toward such parties achieving greater electoral success by moderating extremist profiles. Following this, it highlights the complex relationships found between what are often dubbed "populist" far right political parties and other, more "extreme" forms of activity. Finally, it identifies three major "narratives" found in more extreme far right movements in Europe: neo-Nazi, New Right and anti-Muslim. It concludes that movements animated by such agendas do impact far right political parties. It also stresses academic debate needs to engage with figures outside academia, to create new solutions to the issues raised by variegated forms of far right activity.


Abstract An efficient one-step synthesis of branched functionalized benzenoid compounds from aryl methyl ketones mediated by SOCl2/EtOH is described; some novel C 3-symmetrical molecules were prepared with satisfactory yields. The method enjoys short reaction time and simple operation, and avoids use of organometallic reagents. GRAPHICAL ABSTRACT


The kinetics of SO²⁻₄ adsorption and desorption at 4, 22, and 40°C by untreated and CaCl₂-treated samples of a Cecil Bt2 horizon were studied using miscible displacement and a rapidly stirred batch procedure. Adsorption data was plotted according to the linear forms of the first order, Elovich, parabolic diffusion, and shell progressive particle and film diffusion equations. The latter two equations consider the effects of strong interaction between SO²⁻₄ and the soil surface on diffusion. The shell progressive particle diffusion, the Elovich, and the first-order equations provided the best fits of the adsorption data (R² values > 0.95). The desorption data was best fit by the shell progressive particle diffusion, the Elovich, and the parabolic diffusion equations. Desorption of SO²⁻₄ by KCl was not reversible within a period of two times that of the adsorption period. Decreases in the apparent reaction rate coefficients (slopes of the regression equations) were unexpectedly observed with increasing temperature for the untreated samples, indicating that soil-bound Al may affect the rate of SO²⁻₄ reactions as well as the quantities of SO²⁻₄ adsorbed. Under the assumption that the miscible displacement procedure more accurately models the field situation, a batch equilibrium isotherm procedure overestimated the SO²⁻₄ adsorption capacity, and the rapidly stirred batch procedure underestimated the time required for SO²⁻₄ to react with soil surfaces. Dependency of the reaction rate coefficients on the mixing rate and flow rate, a limited temperature dependency, and the good fit of the data by the shell progressive particle diffusion model indicate that the apparent reaction rate in the miscible displacement procedure is controlled by diffusion of SO²⁻₄ through a reacted soil particle or aggregate rather than an elementary chemical reaction or diffusion through the film surrounding soil particles.


Summary— Microelectrodes were used to study the comparative effects of 2 calcium channel blockers on glucose‐induced electrical activity in mouse beta cells. In 2.8 mM glucose, verapamil (10−5M), but not nifedipine (10−7M), induces a silent depolarization. In 11.1 mM glucose, verapamil (10−7 to 5.10−5M) induces continuous spike activity by a decrease in the maximum repolarization potential. Nifedipine (10−10 to 10−6M) induces the same activity, but subsequent to a hyperpolarization of the cell at the maximal repolarization potential followed by a silent phase to the plateau potential. The 2 drugs induce a dose‐dependent decrease in spike frequency without any change in spike amplitude. In 22 mM glucose exposure to nifedipine, but not to verapamil, induces a transient period of slow‐wave activity. The 2 drugs induce a dose‐dependent decrease in spike frequency. At higher concentrations (nifedipine > 10−7M; verapamil > 10−6M) they induce the disappearance of spikes through a decrease in amplitude. These results show that the beta cell is more sensitive to nifedipine (ED50= 3 times 10−8M) than to verapamil, and that glucose stimulation increases the cell's sensitivity to verapamil (11.1 mM glucose: ED50= 10−5M versus 5times10−7M in 22 mM glucose) but not to nifedipine.