Because of the obvious deformation difference for the alkali resistant glass tubes with different internal stress, in this paper, a new method for evaluating the internal stress and annealing quality of alkali resistant glass tubes based on digital image correlation algorithm is proposed. According to the deformation change rate of alkali resistant glass tube that obtained by digital image correlation algorithm, it can directly determine whether the internal stress meets the production standard. The alkali resistant glass tubes which have undergone abnormal(annealing time less than 5 hours and annealing temperature lower than 630 ℃) and normal annealing operation were selected as samples of experimental group and control group. The samples of these two groups were heated to 200 ℃ and then cooled to room temperature. The displacement fields between deformed images and the initial image are calculated by digital image correlation algorithm and the mean values change rate of the displacement fields are regard as the evaluated basis for the internal stress and annealing quality. Since the new method has many advantages such as simple, efficient and non-contact and only two continuous pictures are required in the detection process, it has been applied in the actual industrial production testing. In addition, this method provides a new approach for the internal stress detection of other solid materials.


In the article the influence of personnel management on efficiency of sale organizations activity is investigated. Eight directions of partner relations creation between an employer and employees are selected with the goal of sale enterprise's competitiveness increase.


Pavement drainage layers have been proved to be highly effective in the efficient and quick dissipation of subsurface water from a pavement structure. The Ministry of Transportation of Ontario requires a 100-mm lift of open-graded drainage layer (OGDL) directly beneath the concrete slab as part of the rigid pavement design for expressway facilities. The gradation of the OGDL consists almost entirely of coarse aggregates retained on the 4.75-mm sieve, which provides a highly permeable drainage layer. Because of this uniformly graded coarse aggregate, the drainage layer has proved difficult to construct by conventional means. In order to alleviate this problem, the OGDL is treated with 1.8% asphalt cement to increase the stability of the material during construction. The addition of an asphalt cement binder has been used successfully on numerous contracts. In 1990, the Ministry initiated a demonstration project to evaluate alternative methods of increasing the constructability of the OGDL. The three types of OGDL placed on this project were (a) a 1-km section of portland cement-treated OGDL with various cement contents [cement-treated permeable base (CTPB)], (b) a 1-km section where no binder was used but the amount of fine aggregate passing the 4.75 mm was increased to improve the stability [untreated permeable base (UTPB)], and (c) the asphalt cement-treated permeable base (ATPB) as just mentioned. The design and construction details are elaborated on in this paper, and the OGDL sections are evaluated in terms of permeability, gradation, constructability, and stability on the basis of falling weight deflectometer test results.


Pseudomyxoma Peritonei (PMP) is a rare disease characterized by disseminated intra-peritoneal implants and mucinous ascites.There is currently no standard treatment strategy for PMP. Presentation of case: We present an unusual case of advanced PMP concomitant with early gastric cancer in a 61-year-old male. In the first operation, in December 2007, the gastric cancer was unrespectable by extensive dissemination of PMP. Therefore, cytoreductive surgery for PMP and appendectomy were performed. After systemic chemotherapy with paclitaxel (Taxo, PTX) plus S-1 for almost 1year, the dissemination on the stomach and intestines disappeared, and we were able to perform a subtotal gastrectomy to remove early gastric cancer. Afterwards, with the intermittent administration of irinotecan (CPT-11) in addition to the basal use of S-1, the patient survived more than five years. To the present day, systemic therapy is still being administered, and might lead to stabilization of disease.


ABSTRACT Through a case study including focus groups with 32 cisgender women and document analysis of campus newspaper and websites, we highlight ways college women navigate multiple and conflicting messages about campus safety and sexual violence on campus. Although students are aware of statistics indicating most sexual violence happens between two people who know each other, they still engage in safety strategies related to stranger danger. We highlight implications related to messaging about campus safety and sexual violence on campuses.


The growth process of silicon carbide crystals by physical vapor transport (PVT) on Si-face (0001) on-axis 6H-SiC substrates was analyzed. The growth rate was observed to be almost inversely proportional to the deposition pressure (R ∝ p-1) meaning that the growth rate is not limited by the number of growth spirals but by the vapor phase transport of the depositing species from the source to the sample surface. Analysis of the spiral step width shows an inverse square root dependence on the growth rate (y0 ∝ R-½). This experimental result is in accordance with the Burton, Cabrera and Frank theory and hence it can be concluded that there is no back-stress effect present.


Gallbladder agenesis (GA) is an uncommon congenital anomaly with an incidence of 0.09%. Lack of awareness, coupled with vague clinical and  radiological characteristics, has led to infrequent preoperative diagnosis. This is the case of a 42-year-old female who presented with right upper  quadrant (RUQ) pain and features of obstructive jaundice. The patient was listed for open cholecystectomy and common bile duct (CBD) exploration for  cholelithiasis and choledocholithiasis. At laparotomy, diagnosis of GA with adhesion bands tethering the duodenum to the common hepatic duct (CHD)  resulting in biliary stricture, was made. Release of the adhesion bands (adhesiolysis) resulted in CHD stricture relaxation and complete biliary  decompression.


The syntheses and structures of five mononuclear zinc and cadmium selone complexes along with a polynuclear cadmium selone 1D chain were described. The mononuclear homoleptic zinc selone complexes were the first examples of structurally characterized zinc(ii) selone complexes. The spectral properties of the zinc and cadmium selone derivatives were investigated. Interesting structural diversity, coordination geometry, and variable chemical and thermal stability were observed for these zinc and cadmium selone compounds. Besides this, the first metal selone mediated Barbier coupling was reported. These catalysts were highly active for Barbier coupling reactions in aqueous alcohol media. In addition, the scope of the catalytic reactions was further explored with eleven different aldehydes.


INTRODUCTION Polymers are the substances of high molecular weight with repeating monomer units widely used in pharmaceutical systems. The chemical reactivity of polymers depends upon chemical nature of their monomer units, but their properties depend upon the way the monomers are put together.[1] Modifications of polymers and their properties is an important technological problem. For realization of this problem, some scientific principles for polymer modification are necessary. The change of structural organization of polymer systems can be used as indicator of polymer modification. The ways to perform polymer modification include interpolymer complexes, protein-polymer conjugates, macromolecular metal complexes and complexes of polymers with low molecular weight compounds.[2] However, use of interpolymer complexation method has wide applications in case of pharmaceutical delivery systems. These include mucoadhesive systems using poly (acrylic acid),[3-5] poloxamer,[4] Poly (vinyl) pyrrolidone;[6] complexation hydrogels using poly(methacrylic acid grafted with poly(ethylene glycol)), (P(MAA-g-EG));[7] controlled drug release;[8,9] nanoparticulates;[10] in situ gelling systems [11] etc. In particular, use of Carbopol as mucoadhesive polymer is widely accepted. It was used in various interpolymer polymer complexes for controlling drug release.[9-12] Poly(vinyl pyrrolidone) (PVP) was used by Gonjari et al.[13] as mucoadhesive polymer for ophthalmic gels. PVP was used for complexation with various other polymers. Chun et al.[14] studied complexation of PVP and poly (acrylic acid). In another study, PVP was complexed with poly vinyl acetate phthalate.[15] Complexation between polymers can be studied by measurement of turbidity, pH, and ionic strength as the function of weight ratio of polymer in media, Research Article


Map use in three metropolitan newspapers in Ohio, the Cleveland Plain Dealer, the Cincinnati Enquirer, and the Columbus Dispatch is sampled between 1930 and 1985. Each has daily and Sunday circulations between 250,000 and 500,000. The frequency of map use, the thematic focus of map-illustrated articles, and the geographic area mapped are all examined. Overall, map use has been limited. Similar temporal trends in map use are demonstrated by each of the newspapers, with increases in the 1940s, 1960s and 1980s. Military conflict dominated the focus of most maps, accounting for 40% of all maps published. Economic resources/development/transportation and tourism/ travel/sports are also important foci of map-illustrated articles, together representing another 25%. Newspapers generally have increased the range of article topics they supplement with maps. In a geographic sense, most maps have focused on areas outside the borders of the United States, almost 60%. Maps focusing on a newspaper's respective metropoli...


Protein-energy wasting, hypoalbuminemia and hypercholesterolemia play an important role in mortality among hemodialysis (HD) patients. How hypoalbuminemia and hypercholesterolemia influence the nutrition (normalized protein catabolic rate (nPCR)) related mortality among HD patients is still unclear.

 Using the nationwide data from the Taiwan Renal Registry Data System (TWRDS) between 2005 and 2012, we divided the HD patients into nPCR<1.2 and nPCR≥1.2 groups. The relation of nPCR with three-year all-cause and cardiovascular mortality were determined. The influence of serum albumin (Alb) and cholesterol (TC) on nPCR related mortality were further analysed.

 Of 88,330 HD patients, 58122 (85.6%) patients were among nPCR <1.2 group and 30,208 (14.4%) in nPCR≥1.2 group. Both all-cause and cardiovascular mortality were increased in nPCR <1.2 group. In the nPCR <1.2 subjects, Alb ≥ 3.7 was associated with increased risk of both overall and CV mortality (adjusted hazard ratio [HR]; 95% confidence interval [CI]: 1.16; 1.07–1.25, p=0.0003 and 1.15; 1.02–1.13, p=0.03) compared to the those with Alb < 3.7 (adjusted hazard ratio [HR]; 95% confidence interval [CI]: 1.00; 0.90–1.08, p=0.74 and 1.15; 1.02–1.31, p=0.03). Further analysis revealed that in nPCR < 1.2 and Alb ≥ 3.7 group, TC ≥ 150 had increased risk of both all-cause and CV mortalities (adjusted hazard ratio [HR]; 95% confidence interval [CI]: 1.14; 1.04–1.25, p=0.005 and 1.17; 1.02–1.35, p=0.026). No significant relation was found betweent mortality and nPCR among patients with Alb < 3.7 irrespective of TC levels.

 From this nationwide study, we found the close relation between dietary protein intake and mortality among those with Alb ≥ 3.7 and TC ≥ 150 group. Thus, we need to emphasize the importance of cholesterol control and dietary protein intake even among HD patients with normal serum albumin levels.


With the aid of WRF(Weather Research and Forecasting) and its 3DVAR system,numerical study with cycling-3DVAR scheme is conducted on direct assimilation of ATOVS radiance data for six sea fog events over the Yellow Sea.A series of contrast experiments are performed,including one non-assimilation simulation and three assimilation ones of GTS(Global Telecommunication System) data only,ATOVS(Advanced Television and Infrared Observation Satellite Operational Vertical Sounder) radiance data only,and both of them,respectively.The simulated sea fog areaes are verified by using satellite-observed fog patches and surface visibility measurements,and analysis of initial conditions that results in differences between these experiments is emphasized.The results indicates: 1) these assimilation experiments can yield good results similar to observations,because they produce the synoptic system that influences the formation of sea fog,and improve temperature and humidity fields at the initial time;2) the assimilation experiment of radiance data only gives a bit better result than that one of GTS data only,and can save plenty of CPU time if radiances only over ocean are used or decreased in density;3) the assimilation experiment of both GTS and radiance data often embodies a compromise effect,and gets the best overall result.


Conference); Ellena and Gennadiy Matveev (Soviet newspapers' coverage of the Paris negotiations); Deona Çali (Turkish Albanians' part in the Albanian representation in Paris); Dariusz Makiłła (the Danzig question); and Wojciech Morawski (a succinct economic account of war reparations in Europe). A couple of articles do not fit into either of these categories. Grzegorz Kucharczyk offers a stunningly Polonocentric (and insufficiently edited) account of German and Polish reactions to the Versailles Treaty, wherein no place is given to the antisemitic background of German postwar frustrations (otherwise analyzed in length), and both countries are counted among the winners of the Peace Conference. One of the most characteristic (and frustrating) features of Kucharczyk's article seems to be the overuse of the ethnic plural: the author's view of history is reduced to an interplay between "great men" and "nations," the latter treated as uniform bodies. On another note, Michael S. Neiberg's interesting study focuses on the American failure to secure peace on the territories and between the nationalities of the nascent Poland, and identifies blind spots in Woodrow Wilson's thinking. Michał Kuź's surprisingly short contribution, opening with a lengthy quotation from Donald Trump, leaves the reader perplexed as to its actual meaning. If, as the author claims, his aim was to offer a history-based view on the viability of the nation-based world order, than this aim remains unfulfilled. Detached from the overarching topic of the volume, Krzysztof Rak describes Józef Piłsudski's foreign policy in the 1920s and 1930s. Finally, the volume closes with a witty and readable piece by Lothar Höbelt on the Anschluss debate in interwar Austria. It seems rather futile to try to establish a logical link between all the texts in the volume. The editors themselves offer no more than vague hints that might facilitate such an understanding, citing the international impact of central Europe as a hotbed of global instability in the interwar period. In fact, the haphazard nature of this selection of articles probably represents its weakest spot. But there are also brighter spots. High-quality traditional diplomatic history, represented by Gmurczyk-Wrońska, Neiberg, and Kornat, is one of them. Some of the minor contributions deal with understudied topics in a sound and well-informed manner: articles on Albanians, Ladins, Kashubians, and Sorbs among them. Both groups of texts would benefit from a more carefully designed construction of the volume. Also of benefit would be greater openness towards social and cultural phenomena other than states and nations. Fortunately, this volume does not represent the current trends in historiography of post-1919 central Europe. With all its flaws and lacunae, the latter is much richer and livelier than readers of this book might assume.


TCSC (Thyristor Controlled Series Compensation) are FACTS devices which contribute substantially to the improvement of the dynamic stability of power systems. The series compensation technology uses TCR (Thyristor Controlled Reactor), very similar to the classical shunt compensation by means of an SVC. However, the TCSC ́s control can only be applied effectively if the TCSC scheme and its rating as well as the control and protection circuits are well matched to the specific network parameters and the specification requirements. Hence, design verification by real-time simulation is imperative to successful TCSC operational performance. In this paper, the use of a new fully digital RTDS TM (Real Time Digital Simulator) model for the dynamic testing of TCSC control and protection functions is presented. RTDS uses fast DSP (digital signal processors) technology with standard models on TPC (NEC Tandem processor card) in combination with the new 3PC (SHARC 3 processor cards) for advanced modelling requirements like the fully digital TCSC. This TCSC model has been developed and verified for the Serra da Mesa project in Brazil. It is suitable for combining with physical plant control and protection equipment. In the development of the TCSC model, special attention was given to the specific requirements for testing the latest developments of the series compensation including the hybrid optical current measuring techniques. These measurements are likely to revolutionise the design of the protection schemes for TCSC. Highlights of the control and protection tests for the scheme hard and software equipment in the simulator are presented and compared with site-recordings.


This paper describes a method to effectively reduce the unbalanced vibration of an overhung rotor system. We propose a hybrid type damping device in which a bearing pedestal is supported elastically by rubber springs and controlled actively by electromagnetic actuators. The damping device is mounted in a motor casing which is set on an elastic stand. When the damping device is supported elastically, the suppression effect often deteriorates. In order to prevent this deterioration, we apply a stiffness control which is achieved by conducting positive feedback of the displacement signal. In the analysis, we calculate the controller gains that minimized the compliance of the overhung portion in consideration of the stand stiffness. In the experiment, the results correspond to the analytical results, and we confirm that the application of the stiffness controller is a highly effective method for vibration suppression.


Alzheimer is generally known to be a problem with brain such as thinking, memory, and thinking. Many researchers have implemented various classification algorithms before, which have an average accuracy of 69%. In this paper, the algorithms which is implemented shows the accuracy more than the existing work. Pre-processing is done in finding out the null values and duplicate records of the patients visiting for assessment. Here application of different classification algorithms such as SVC, Random Forest Classifier, Logistic Regression, Neighbor Classifier and Decision Tree Classifier for predicting the presence of Alzheimer in the patients the proposed work the number of visits count of the patients are considered as an important factor. Each visit of the patients is taken into considerations calculating the maximum number of visits of each individual patient. The Performance measures are calculated for each classification algorithms applied in the prediction of the existence of the disease. The work of the proposed application can be considered effectively for diagnosing and determining the severity of Alzheimer Disease. Based on the performance measures each accuracy is being identified. Among all the Classification algorithms implemented for predicting Logistic regression shows high accuracy of 73%.


The use of crop practices to reduce the weed community is an ally to integrated weed management. Given this, the study aimed to identify a composition and weed infestation in a soybean area under different predecessor crops implanted in different years. The experiment was carried out in the 2019/2020 harvest in Dourados, MS. The experimental design was a randomized block with nine treatments. The treatments were composed of autumnwinter crops. The area with predecessor cultivation: corn-Brachiaria intercropping; cowpea beans; single corn; an area with predecessor cultivation of Brachiaria as pasture for one year; two years; three years; four years; five years, and six years. All treatments were followed by soybean cultivation in the 2018/2019 harvest and an intercropping with corn and Brachiaria in the 2019 off-season harvest. There was a difference in the absolute weed infestation between the evaluated areas. Treatments with corn and cowpea had greater weed infestation. However, areas with pasture or intercropping with corn and Brachiaria showed less infestation, especially in areas with Brachiaria grown in the off-season for more than two years. The weed species composition differs between the areas evaluated. The implantation of a corn-Brachiaria intercropping in the off-season under a crop rotation system, especially in areas with Brachiaria grown in the off-season for more than four years, reduces the weed infestation.


The political perception of New Zealand's broadband market performance as 'poor' has underpinned many significant changes to the telecommunications policy and regulatory environments since 2001. Most recently, this has been manifested in substantial government subsidies by way of public-private partnerships (PPPs) for an ultra-fast broadband (UFB) network that promises to deliver fibre connections with upload/download speeds of 100Mbps/50Mbps to 75% of New Zealanders by 2019. Bert Sadowski and Bronwyn Howell explore the pros and cons of the New Zealand PPPs.


The international composition of the whaling fleets that sought Balaena mysticetus north of Canada before 1915 has long been a deterrent to the compilation of a complete set of voyage and catch data. Using unpublished whaling logbooks and journals, manuscript annual summaries of Dutch and British whaling, and other sources, the author assembles data annually for each of the whaling grounds of Davis Strait, Hudson Bay, and the Beaufort Sea, which indicate that more than 29,000 whales were secured. Considering gaps in the coverage and the mortality of wounded escaped whales, the total kill during the whaling period may have exceeded 38,000. This reconstruction is considered preliminary; additional research could improve the completeness and accuracy of the information.


MALIGNANT otitis externa is an inflammatory condition of the external auditory meatus which occursjn elderly diabetics. The infection is caused _by the Pseudomonas Pyocyaneous and is characterized by extensive necrosis of cartilage and bone. The disease is non-neoplastic in aetiology and the unfortunate term 'malignant' is used only to denote the fact that it usually runs a pernicious course ending in death. In this article we review the seventeen cases reported in the literature and add two of our own.


BitTorrent is the dominating protocol in nearly all regions. Various reputation models and incentive mechanisms are proposed in recent years. However, many of them are designed for general peer-to-peer networks, only a few are designed for BitTorrent even though some models and mechanisms assert that they can be applied to BitTorrent-like systems. In this paper, we propose an incentive framework based on reputation history instead of tit-for-tat in BitTorrent. It is derived from the coalition games concept of Shapley value that will encourage selfish peers who seek to maximize their own profits to converge to Nash equilibrium. We show that this profit sharing framework exhibits several fairness properties that support the argument that this distribution of profit is desirable. Moreover, we improve SepRep reputation model and tailor it to the needs of BitTorrent protocol. In particular, we utilize the tracker of BitTorrent to process global reputation and trust values assisting the local values maintained by each peer.


Purpose
This paper aims to examine the mediating effect of work engagement on the relationship between curiosity and innovative work behavior. The context of the study is the initial stages of the pandemic starting April 2020, when international travel became restricted.

Design/methodology/approach
Self-administered questionnaires were distributed and collected from 327 respondents of 32 organizations in the aviation industry in the United Arab Emirates (UAE).

Findings
As hypothesized, work engagement is a mediator of the relationship between curiosity and innovative work behavior.

Research limitations/implications
The limited sample size and confinement to the aviation industry in the UAE limit the generalisation of the results.

Practical implications
Managers desirous of improving employees' innovative work behavior will now understand how employees' curiosity and exploration can impact innovative work behavior through the employees' work engagement. Therefore, managers should focus on ensuring how employees' curiosity and exploration can be created into work engagement, ultimately leading to innovative work behavior.

Originality/value
This research extends the social learning theory by positing that people who have strong traits of curiosity and exploration, will learn from others on how to work more effectively. This will make them more absorbed in their work (work engagement) and subsequently lead to innovative work behavior.


This study introduces a novel, game-like method for measuring social intelligence: the Social Shapes Test. Unlike other existing video or game-based tests, the Shapes Test uses animations of abstract shapes to represent social interactions. We explore demographic differences in Shapes Test scores compared to a written situational judgment test. Gender and race/ethnicity only had meaningful effects on written SJT scores while no effects were found for Shapes Test scores. This pattern of results remained after controlling for general mental ability and English language exposure. We also found metric invariance between demographic groups for both tests. Our results demonstrate the potential for using animated shape tasks as an alternative to written SJTs when designing future game-based assessments.


Background: Neuropathic pain is a form of chronic pain that arises from functional changes in the pain sensory system after peripheral nerve injury. It is manifested by spontaneous pain, hyperalgesia and allodynia. Calcitonin gene related peptide (CGRP) is 37 amino acid neuropeptide that is widely distributed in the central and peripheral nervous system and is involved in processing of nociceptive information. Evidences from human and animal studies whether estrogen is pro or antinociceptive is inconsistent. Transcutaneous electric nerve stimulation (TENS) is a non pharmacologic therapy for pain used to produce analgesia in inflammatory conditions. Aim of the present work was assessment of pain and spinal cord levels of CGRP and interleukin-6 (IL-6) in a model of neuropathic pain induced in female rats by chronic constriction injury (CCI) of sciatic nerve. The possible modulation of neuropathic pain by estradiol and TENS was also assessed in ovariectomized rats with CCI of sciatic nerve. Material & Methods: The study was carried out on 48 adult female rats divided into six groups (8 rats/each). Group 1: sham operated rats, group II: CCI of sciatic nerve in gonadally intact female rats, group III: ovariectomized (OVX) rats, group IV: OVX+CCI, group V: OVX+CCI/17  estradiol, group VI: OVX+ CCI/TENS. All ovariectomized rats were included in the study 3 weeks after ovariectomy for depletion of circulating estrogen. Exogenous estrogen was given to ovarietomized rats of group V as 6g/kg body weight (b.wt.) per day subcutaneous for 3 weeks starting on the same day of CCI-surgery (day 0). TENS was delivered to OVX+CCI rats (group VI) starting from day 0 and continued for 3 weeks on alternate days under light ether anaesthesia. Pain behavior was assessed by pin prick test. Mechanical hyperalgesia was defined as increased hindpaw withdrawal frequencies percent (PWF%) to mechanical stimuli. The assessment began on the day of CCI surgery (day 0) before the operation (pre-operative, baseline data) and followed up weekly on post-CCI days 8, 14 and 21 (post operative assessment). Ovariectomized rats that were not subjected to CCI (group III) followed the same schedule for assessment of PWF%. At the end of the experiment, rats were sacrificed, lumbar spinal cord was dissected and used for later assessment of mRNA expression of calcitonin gene-related peptide (CGRP) using an Reverse transcriptase –Polymerase chain reaction (RT-PCR) method. Also levels of CGRP and IL-6 in the spinal cord were assessed by Enzyme Immunoassay Kits. Results: The expression of CGRP in the spinal cord tissue, levels of CGRP and IL-6 were significantly higher in lumbar spinal cord after CCI, OVX or OVX+CCI compared with sham operated rats. After estrogen or TENS therapy, a significant decrease of expression of CGRP, levels of CGRP and IL-6 were found compared with untreated (OVX+CCI) group. However, the values of CGRP and IL-6 after treatment were still above control level. Rats in group II (CCT of sciatic nerve in gonadally intact female rats) had significant increase of PWF% on post-CCI days 8, 14 and 21. Group III: OVX rats had significant increase of PWF% on day 0 and post-CCI days 8,14 and 21 versus sham operated rats. Group IV (OVX+CCI) showed significant increase of PWF% on days 8, 14 and 21 post-CCI compared to baseline. These values were significantly higher than those of sham operated rats. PWF% in group IV (OVX+CCI) tended to be higher at all the time points of post-CCI follow up than corresponding values in group II (CCI in gonadally intact females) and the difference was statistically significant on day 14. Group V (OVX+CCI/17  estradiol) showed significant decrease of PWF% starting from day 8 and continued on days 14 and 21 post-CCI versus baseline, but remained significantly higher than sham operated rats. Group VI: OVX+CCI/TENS showed significant decrease of PWF% on post-CCI days 8, 14 and 21 compared with baseline, but remained significantly higher than sham operated controls. No statistically significant differences in PWF% were found between estradiol and TENS treated groups on post CCI days 8, 14 and 21. Conclusion: increased spinal cord levels of CGRP and IL-6 could be involved in the mechanism of mechanical hyperalgesia after CCI surgery of sciatic nerve and ovariectomy. Administration of estradiol or TENS significantly attenuated the development of hyperalgesia in (OVX+CCI) group, possibly by decreasing spinal cord levels of CGRP and IL-6. The findings suggested that TENS can be considered as alternative to hormonal therapy for neuropathic pain in ovariectomized rats. [Gihan Sharara, Hala M. Abou Heif and Abeer El-Emam Deif. Assessment of Pain and Spinal Cord levels of Calcitonin Gene Related Peptide and Interleukin-6 in a Model of Neuropathic Pain in Female Rats. J Am Sci 2012;8(6):145-157]. (ISSN: 1545-1003). http://www.sciencepub.net/american. 18


Explosion of spatial data from satellite to citizen sensors has posed the critical challenge of Big Spatial Data integration, analysis, and visualization. This article focuses on research and development activities at Oak Ridge National Laboratory (ORNL) that are addressing end-user applications utilizing high performance computing based geospatial science and technology solutions to optimize the analysis, modeling, and multi-megapixel scale visualization of the geospatial data. Specifically we highlight recent developments and successes in the areas of high resolution settlement mapping, transportation and mobility analysis, and effective monitoring of biomass for energy and food security.


half of the acre area, we have a nitrogen yield of 45 pounds per acre from our cover crop, which is from one-third to one-half of the total nitrogen required to produce the crop. Summing up, then: Indigo is highly resistant to root-knot. It appears that indigo is not a preferred host plant of pumpkin bugs. Indigo should be seeded in the spring at the rate of 4 to 8 pounds per acre, depending on the method used. Indigo does not require inoculation nor special fertilization when sown in citrus groves. Indigo gives comparatively high yields of green weight per acre. It appears from the limited amount of avail able information that indigo does not delay maturity in citrus.


 Abstract - High rise Structures are in demand due to scarcity of land in urban areas, economic growth, technological advancement, etc. Wind effect is very important for high rise structures and provides significant contribution to overall loading and serviceability. In order to provide design load and predict dynamic response, wind tunnel testing is an essential component in designing high rise building. As the wind tunnel testing is generally very expensive and time consuming, the use of CFD as an alternative to wind tunnel testing is studied. Different RCC buildings of varying shapes and aspect ratios are studied. An attempt is made to study the effect of different geometric configurations like flared, swastika, circular and tetragon of tall buildings having same plan area on Force coefficient. To study the wind effect, overturning moments, drag forces and torsional moments at base of the structures using Computational Fluid Dynamics(CFD) that is nothing but ANSYS FLUENT workbench. Then the numerical computation has been executed to validate the results of the same.


This paper reports a study exploring the possibilities of virtual reality (VR) and head mounted display as a stress recovery solution for workplace. Commercially available low-cost head mounted display (HMD) was used for presenting three different 360° videos of nature scenes, -sounds and calm music. Six experiment sessions were arranged for each participant and within subject approach was followed i.e. half of the sessions were completed with full VR condition and half with audio only condition without the HMD. During the experiment sessions, heart rate (HR), heart rate variability (HRV), and skin conductance (GSR) was recorded. Also, blood pressure (BP) were measured three times during the session. In addition, a post experiment questionnaire was filled out assessing the relaxation and distraction effect. GSR and HR got significantly lower during the VR experience. The effect was stronger in audio only-condition. Systolic BP decreased from the beginning of the session till the end of the VR experience but no difference between the VR conditions (full VR vs. audio only) was detected. In HRV analysis, no significant differences were found between the conditions. Questionnaire responses revealed that the participants got significantly better distracted from the work related thoughts and duties in the full VR condition. The results suggest that low-cost VR technology with relaxing content can provide a satisfactory solution for stress recovery and help in distraction from work duties.


CERES–Rice model (DSSAT v. 4.0) was calibrated and evaluated for cultivar IR 36 at Cuttack, Orissa using experimental data of wet seasons (June-December) 2001 and 2002. The model accurately predicted phenological events i.e. flowering and maturity date. The simulated grain yield at different N levels was in close agreement with experimental grain yield. Application of the model for solar radiation stress assessment due to Atmospheric Brown Clouds on the same site during dry season (January-May) on historical weather data (1983-2002) revealed a reduction in rice grain yield by 4% with reduction of incident solar radiation by 30% under non-fertilized condition. Compared to non-fertilized condition, grain yield reduction was higher up to 12% with similar solar radiation stress under high rates of N application (120 kg N ha -1 ). The reduction in grain yield is associated with lower grain formation.


Thickfilm is an essential part of inkjet printheads. In the printheads used in Lexmark's 1100 series of printers , a dry fil m photosensitiv e laminate material is used to create the ink flow channels and to form an integral unit between the heater chip and the nozzle plate. In the printhead s used for Lexmark's 7000 and 5700 series of printers, a liquid spin on photosensitive material is used to passivate the chip surface, planarize the chip surface, and promote adhesion between the nozzle plate and the chip. Both processes will be presented.


We examined the importance of T cell‐independent B cell activity in the resolution of primary murine (EDIM) rotavirus infection in adult mice. We showed that Rag 1 (C57BL / 6 background) and Rag 2 (BALB / c background) knockout mice, which lack both T and B cells, chronically shed high levels of rotavirus Ag in stool samples following oral inoculation. However, nude mice (BALB / c and C57BL / 6 backgrounds) and α β TCR knockout mice (C57BL / 6 background) chronically shed 100‐fold lower levels of virus in stool samples. Thus, B cells appeared to sharply reduce the level of chronic rotavirus shedding by a T cell‐independent mechanism. C57BL / 6 mice depleted of CD4+ cells or both CD4+ and CD8+ cells were also unable to resolve primary rotavirus infection but chronically shed equally low levels of rotavirus Ag in stool samples, whereas mice depleted of only CD8+ cells resolved infection. Similar results were obtained with a second rotavirus strain (ECw) in which virus was shed chronically in stool samples at low levels in α β TCR knockout mice and at high levels in Rag 1 knockout mice. Virus‐specific intestinal IgA was readily detected in mice lacking thymic T cells and α β T cells and in mice depleted of CD4+ cells but levels were 95 % reduced in comparison to immunocompetent controlmice. Together, these results show that B cells lacking CD4+ T cell help have the capacity to substantially reduce rotavirus shedding, possibly through the production of T cell‐independentIgA to rotavirus, but full resolution requires α β T cells.


The probability that the near-extreme occurrence of a physical phenomenon (e.g., the largest rainfall, the second largest flood) will exceed a selected value is important in many geophysical problems. A simplified technique for computing this probability which is applicable to a wide class of problems is presented. Utilized in the method is a tabulation of the percentage points for the exact frequency distribution of the mth largest of n values (m = 1, 2, 3, 4, 5; m≦n≦∞) in terms of the parameter n[1 - F(x)]. The procedure can be used for samples either of fixed or random sizes and is particularly applicable if (1) data are missing or unreliable, (2) the sample size is small, or (3) it is desired to check an assumed population distribution against the observed near extremes. The technique is illustrated by various applications.


Anther culture response in a diverse range of Australian wheat-breeding genotypes was tested and expressed as a 'culturability index' based on the actual costs of the various laboratory procedures. When the delay from harvest to plating was up to 12 h, the use of low dose gamma irradiation did not increase the anther culture response in this array of genotypes. This is in contrast to previous findings for which spike harvesting, irradiation, and plating was completed within 3 h and the irradiation treatment increased the anther culture response. Internal contamination of immature spike explants with Fusarium poae caused significant loss of cultures and may be a persistent problem for cereal anther culture. For the genotypes producing green regenerants, costs ranged from $A1.40 to $85/green regenerant.


In their Comment (DOI: 10.1021/jacs.2c02965) on two related publications by our group (J. Am. Chem. Soc.2022, 144, 1380–1388; DOI: 10.1021/jacs.1c11754) and another (J. Am. Chem. Soc.2021, 143, 20884–20890; DOI: 10.1021/jacs.1c09455), Huang and Granick refer to the diffusion NMR measurements of molecules during a copper-catalyzed azide–alkyne cycloaddition (CuAAC) "click" reaction. Here we respond to their comments and maintain that no measurable diffusion enhancement was observed during the reaction. We expand on the physical arguments presented in our original JACS Article regarding the appropriate reference state for the diffusion coefficient and present new data showing that the use of other reference states, as suggested by Huang and Granick, will still support our conclusion that the two reactants and one product of the CuAAC reaction do not exhibit boosted mobility during the reaction.


Abstract This paper explores what the research says about the risks to children and young people of using social media. Taking a systematic approach this literature search identified 16 peer reviewed articles, written in English since January 2010. Four areas of risk were identified: cyberbullying and online abuse, exposure to negative forms of user-generated content, the converging of offline and online networks, and developing interpretations of privacy. The research also highlighted how the extent of the risk depends upon the developmental stage and social circumstances. This review provides several implications for social work practice. Social workers must develop their understanding of different social media platforms in order to identify risks and maximise opportunities. Assessment approaches must be tailored to ensure social media use and its effect on those of different ages and backgrounds is considered. Finally they need to consider their role in educating about the risks of social media use.


Percutaneous kidney biopsy is an essential clinical tool for the assessment of a multitude of kidney disorders. In addition to providing key diagnostic information that is commonly unattainable from blood, urine, and radiographic testing, the findings of kidney biopsies inform clinical decisions


A new alternative manufacturing method using focused-ion-beam (FIB) technology is introduced in detail in this article. Fabrication of microcylindrical lenses can be realized based on SiO2 deposition and FIB milling. The former is suitable for fabricating directly on the surface of the microdevice. The latter is generally used for milling on chip-integrated microcomponents. The form accuracy can be precisely controlled by varying the parameters, such as the ion dose, accelerating voltage, beam current, etc. We analyzed in detail the influence of implanted Ga+ in the microlens and the precursor partial pressure of H2O and tetramethylcyclotetrasiloxane during the SiO2 microlens deposition on transmission. The experimental results and quality of the microlens using different methods are presented. We conclude that microfabrication of microcylindrical lenses using both FIB milling and deposition is practicable.


During recent decades, mangrove forests have experienced severe degradation due to unsustainable land use. Restoration of mangrove ecosystems requires the recovery of their habitat, considering ecology, hydrology, hydrodynamics, and sediment transport. In a first pilot in 2013, brushwood dams were built on the eroding coast of Demak, Indonesia, in order to emulate the function of mangrove roots and provide the physical conditions for natural colonization. However, at present there is little research on how soft structures affect the local hydrodynamics. The present study aims to improve the understanding of wave attenuation by permeable brushwood dams in Demak, combining field observations and hydrodynamic modelling using Delft3D. The findings of the study will be used to develop a landscape bio-morphodynamic model, which will be applied for planning future mangrove restoration efforts.


Nausea is a common problem in ED patients. Antiemetic drugs have been used in the ED for decades, but a recent Cochrane review found no convincing evidence for the benefit of antiemetic drugs over placebo. This was largely based on three placebo‐controlled trials, which found mean Visual Analog Scale (VAS) changes for various drugs and placebo, to be similar. However, reliance on mean VAS change as the primary outcome measure has probably been a mistake. It does not give information on the number of improved patients, so these cannot be compared between groups. Alternative primary outcome measures warrant further exploration. Use of a VAS cut‐off level indicative of clinically significant symptom improvement would allow comparison of numbers of patients with improved nausea ratings. This is proposed as the best option currently available. Preliminary testing of this outcome measure suggests that the conclusions of past studies may be misleading, and that the question of antiemetic efficacy for ED patients is not yet answered.


Allergic asthma is a common chronic inflammatory disease of the lungs that affects 10% of the population in developed countries. Asthma shows a sex difference with more boys than girls diagnosed before puberty. In adulthood, women are twice as likely to have asthma than men. Women can also have increased disease severity and be less responsive to corticosteroid treatment. Sex hormones therefore may be important in asthma. Asthmatics have more and a greater percentage of M2 macrophages in their lungs than healthy individuals. Mouse studies have also demonstrated that M2 macrophages contribute to worse allergic lung inflammation. Furthermore, estrogen (E2) stimulates the production of M2 macrophage‐related cytokines that promote lung remodeling. How sex steroids affect monocyte‐macrophages to enhance M2 polarization is still unknown.


In this piece reviewing Mark Tushnet's "The New Constitutional Order," David Fontana argues that Tushnet's admirably comprehensive book faces some of the same problems that many other pieces of popular constitutionalism scholarship do: He discusses the Constitution outside of the courts without examining the actual behavior of the Constitution outside of the courts. As it turns out, Tushnet is mostly right that there has not been a major constitutional revolution in the past generation. Still, by understudying the behavior of institutions besides courts, the book does not focus enough on the extent to which the entire political dynamic has moved to the right in the past generation, so no matter what that dynamic produces, it is bound to be farther to the right than the policies of a generation ago.


One of the problems with many partial-order planners is their eager commitment to variable bindings. This is contrary to their control decision in delayed-commitment of operator orderings. In this paper we present an extension to the classical partial-order planners by associating every variable with a finite domain of values. The extended planner applies constraint satisfaction routines to check for the consistency of variable bindings. With the extended planner, we perform a set of experiments to show that it is able to reduce the amount of backtracking in domains where few variable instantiations can lead to final solutions. We also investigate the frequency of CSP application to determine how often should constraint checking be performed in order to yield the best performance.


The Army's equipage repair and safeguad enterprises is not only an important component of the PLA's equipage ability development,but also the key permeated aim of the enemy spy.To ensure security of the army's equipage repair and safeguard enterprises is related to life and death of the enterprise,and even it is the political requisition.This paper,based on the security work's current situation of the army's equipage repair and safeguard enterprises,and the existent questions,explores how to develop the security work in the light of their own actual conditions.


The use of copper(I) Schiff base complex catalysed atom transfer polymerisation of methacrylates is described. The use of a range of functional and multi-functional initiators enables the synthesis of a range of functional and star polymers to be prepared under undemanding synthetic conditions. End capping with silyl enol ethers allows for ω-functional polymers. The combination of novel initiators, functional monomers and end capping allows an unprecedented array of macromolecular structures to be produced with limited need for protecting group chemistry.


Abstract:  Infection of the eyelids confined to the preseptal space is relatively common but potentially serious. We report a child with cutaneous anthrax to remind that the interesting contagious cause be included in the differential diagnosis of the preseptal cellulitis.


To examine the effect of adding automated fetal fractional limb volume (FLV) with conventional 2‐dimensional (2D) fetal weight estimation procedures in a cohort of diabetic pregnancies.


The no-reform of the Italian labour market. Many different and passionate comments have been published in the past weeks about the Italian labour market reform. The topic is for sure very relevant from the economic and political perspective, and it is also a sort of "litmus paper†of the technical ability and political orientation of the Professor Monti Government. There is a clear and strong idea underpinning the labour market reform proposed by the government: the extension of the rights to somebody must be associated with a reduction of the rights of somebody else, a sort of exchange between generations, between the elderly and the youngs in the labour market. In the following comment we leave this idea and its economic robustness at the side, notwithstanding it has relevant political implications. We address our critics to an internal (in)consistency of the proposed reform in three areas: (1) reduction in the misuse of flexible contracts and incentive to subordinate labour contracts; (2) restructuring of the unemployment subsidies; (3) reduction of the firing costs. We argue that the proposed reform does not provide neither prepare the necessary novelty in the functioning of the Italian labour market, as it does not seem to introduce effective leverages and stimula to favour the expected and widely asked growth path for the economy. With the proposed reform there is the serious risk to maintain the existing labour market, with probably increased costs for firms and without expanding opportunities for job growth.


The purpose of this article is to provide an overview of the research activities in photonics and optoelectronics being carried out at the University of Cincinnati (UC). The article presents brief summaries of several topics covering research in optical sensors, near-field optical microscopy, optical displays, optical memory, visible and infrared light emitters. The summaries are certainly not comprehensive, nor does this article capture the totality of photonics-related research at UC. It is only intended to provide a window on our activities through which we encourage the readers to learn more by contacting us. Faculty with interest in photonics and optoelectronics at UC span a variety of disciplines including Electrical Engineering, Materials Science, Physics, Medicine, etc. Compiled by Prof. A. J. Steckl University of Cincinnati Cincinnati, OH 45221 (firstname.lastname@example.com)


Abstract This article is devoted to poverty and wealth presented in fiction films - both cinema and television - directed in the times of the Polish People's Republic. Poverty and wealth shown intentionally and unintentionally in these films manifest themselves in many ways. If we want to learn anything about wealth of the society shown in a given movie, a critical approach must be applied


【This paper is aimed to study on sales promotion strategies for the increment of farm income by cultivating Boxthron in Chongyang Area. Marketing Survey was done in Chongyang Boxthron market, Kyoung-dong herb market in Seoul. The results are as follows ; Reviewing the Boxthron market prices, the price of direct transaction was the highest one and that of Agricultural Cooperatives was next one, Chongyang market price was lowest one. Therefore, the efforts including exclusive labeling, high class packing strategies of Boxthron with lower pollution would be necessary. The seasonal variation Boxthron prices were lowest in Aug.-Sept., harvesting season, and highest in april-june prices, off-crop season. Farmers have sold 45% of all products in Aug.-Oct. at lowest price and the remaining 15% of that sold in april-june at the highest prices. On account of the above reasons, loan for Boxthron production, government purchasing and storage program of it especially in harvesting season from Aug. to Oct. should be adopted to increase Boxthron producer income. Finally, the strategies for sales promotion, enforcement of government supporting activities including export strategies and the development of new processed products of Boxthron should be propelled considering the products cycle.】


The growth in context-aware systems and smart devices elevates another technology in ubiquitous computing - Internet of Things (IoT), where all objects are connected. The integration of Smart objects and social networking play an important role in today's life. This paper mainly promotes the management and architecture for adaptive social services within IoT, where objects interact based on social behavior. We proposed social context-aware and ontology as the major keys for this study. Our main goal is to make the presented framework CANthings a standard social framework that can be used both in research and industry projects.


The present invention relates to a process for recovering bitumen from oil sands, the method comprising the following stages in sequence: (a) capable of reducing the oil sands and the diluent contained in oil sands bitumen viscosity and density, obtained cutback asphalt comprising first mixture (slurry); (B) the slurry from the diluted bitumen capable of removing the oil contained in the dilution of the bitumen sands and optionally containing salts to increase the ionic strength of the base aqueous solution (BAS) were mixed to give a second mixture can be separated into the following (BAS-slurry) :( i) liquid phase comprising the cutback asphalt, of the free portion of the oil sands bitumen and water removal; ( ii) deposit, the oil sands comprising bitumen-free removal of the remaining portion, and the water can be removed by subsequent washing of the residual hydrocarbons; (c) a liquid phase comprising the removal of bitumen is diluted with the the slurry mixture was separated BAS-; (d) the cutback asphalt comprising wherein the liquid phase removed from the separation stage (c) is recovered.


A surveillance system has been developed that can use multiple TV-cameras to detect and track personnel and objects in real time in public areas. The document describes the development and the system setup. The system is called NIVS Networked Intelligent Video Surveillance. Persons in the images are tracked and displayed on a 3D map of the surveyed area.


Objective: The objective of this study was to discover the possible correlation between p16INK4A expression and the LR/HR-HPV infection in condyloma acuminate (CA) lesions. Materials and Method: This cross-sectional study was conducted during January-December 2017 on 33 CA patients. The expression of p16INK4A was detected by immunohistochemistry (IHC) staining. The positive interpretation was carried out by scoring which score 0 was negative, score 1 was sporadic, score 2 was focal, and score 3 was diffuses. The HPV genotypes were identified by reverse line blot, and 40 genotypes of HPV detected, including HR-HPV (HPVs 16, 18, 26, 31, 33,35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, 68a, 68b, 69, 73, and 82) and LR-HPV (HPVs 6, 11, 40, 42, 43, 44, 54, 55, 61, 62, 64, 70, 71, 72, 81, 83, 84, 87, 89, and 90). Results: The expression of p16INK4A was significantly correlated with HR-HPV infection. Patients infected with HR-HPV had 0.644 times higher possibility to express p16INK4A gene compared to those infected with LR-HPV. LR-HPV genotypes detected in CA patients were HPVs 6, 11, 42, 61, 54, 81, 87, 89, and 90 and HR-HPV genotypes were HPVs 18, 26, 45, 51, 52, 67, 68B, 69, and 82. LR-HPV was found in 19/33 of patients and HR-HPV was in 14/33 of patients. The expression of p16INK4A in CA lesions was diffuse in15.2% of patients, was focal in 24.2% of patients , was sporadic in 39.4% of patients were, and was negative in 21.2% of patients . In LR-HPV group, there was no diffuse expression, focal expression was observed in 15.8%, sporadic in 47.4%, and negative in 36.8%, while in HR-HPV group, p16INK4A expression was detected in all lesions , in a way that its expression was diffuse in 35.7%, focal in 35.7%, and sporadic in 28.6%. Conclusion: IHC is a routine method in histopathological diagnosis, therefore the detection of p16INK4A expression by IHC can be used as a biomarker for HR-HPV infection diagnosis.


STRUCTURE AND COMPOSITION OF ELECTRODES AND ELECTROLYTES: Techniques for the Study of Solid Ionic Conductors Ellipsometry as an In Situ Probe for Study of Electrode Processes In Situ Characterization of Electrode Processes by Photothermal Deflection Spectroscopy Surface X-Ray Absorption Spectroscopy, EXAFS and NEXAFS for the In Situ and Ex Situ Study of Electrodes Surface-Enhanced Raman Spectroscopy In Situ Characterization of Electrodes by Neutron Scattering Diffraction Techniques for Determining the Structure of Electrolytes in the Liquid Phase Moessbauer Spectroscopy Laser Interferometry Study of Mass Transport Limitation in Electro-Deposition of Metals/Polymers. ELECTROCHEMICAL MEASUREMENT TECHNIQUES: An Introduction to Electrochemistry in Molten Salts Application of Electrochemical Impedance Spectroscopy in Electrochemistry and Corrosion Science Electrochemical Impedance Spectroscopy (EIS)- Application in Corrosion Science and Technology Numerical Techniques for Modeling Current Distribution at Plane or Flow-By Electrodes Experimental Simulation of Porous Electrodes Techniques for Study of Nucleation during Metal Electrodisposition.


The heavy-fermion superconductors show the most significant differences from conventional superconductors. Heavy fermions are compounds containing rare-earth or actinide ions whose f-shell electrons are strongly correlated. The theories presented in this paper were developed mainly to describe effects in heavy fermion superconductors. Nevertheless, the general aspects of these theories may also be applicable to the class of CUD or organic superconductors. Nigerian Journal of Physics Vol. 16(2) 2004: 40-48


A method of cylindrical grinding in the manufacture of tools of hard metal on a cylindrical grinder comprising a workpiece headstock and a tailstock, wherein it is assumed that a group consisting of cemented carbide round rod as a starting material, characterized by the following process steps: a) clamping the cylindrical rod (6), whose length is a multiple of the length of a single tool (in a chuck 4) of the workpiece headstock (3) which enables (when dissolved chuck 4) an axial displacement of said cylindrical rod (6), wherein a out of the workpiece headstock (3) outstanding end portion (23) of said cylindrical rod (6) facing said tailstock (7); b) grinding at least one steady rest (35, 36) (at the (from the workpiece spindle headstock 3) protruding end portion 23) of the round rod (6) and queuing of the bezel (11, 12) to the steady rest (35, 36); c) grinding a first end cone (37) to the (the tailstock 7) facing the end face of said cylindrical rod (6); d) fixed exciting driving interengagement of the first end cone (37) having a hollow grains (10) extending ...


Introduction: By the interactive Mathematica Demonstrations of the Wolfram Research instrumentation [1], several mechanics for space probe operation and motion simulations were studied. The created great number of Mathematica demonstrations are available on the Wolfram Demonstration website.. About Mathematica: The possibilities of the newest version of Mathematica makes it excellent learning ability to interactively manipulating graphics for the movement and animation of modeling by using great number of parameters for the structure studied. Rich parametrization helps the architectures to fold, extend, unfold, retract, enlarge and diminish, rotate etc. The new possibilities generate new needs in costruction design. One of them is the stereoscopic view. But spatial motions extend spatial feeling and viewing. The movement representations give extended robotic motion planning opportunities. All these activities serve students in space science education and in design, too. Moving elements on terrestrial machines: Swash Plate Drive. A disk with adjustable inclination (swash plate) is attached to a rotating shaft. Rods, aligned with the axis, move back and forth as the disk rotates. This arrangement is used to drive pistons and to adjust the angle of helicopter rotor blades


This report documents the conceptual design of the Hot Conditioning System Equipment. The Hot conditioning System will consist of two separate designs: the Hot Conditioning System Equipment; and the Hot Conditioning System Annex. The Hot Conditioning System Equipment Design includes the equipment such as ovens, vacuum pumps, inert gas delivery systems, etc.necessary to condition spent nuclear fuel currently in storage in the K Basins of the Hanford Site. The Hot Conditioning System Annex consists of the facility of house the Hot Conditioning System. The Hot Conditioning System will be housed in an annex to the Canister Storage Building. The Hot Conditioning System will consist of pits in the floor which contain ovens in which the spent nuclear will be conditioned prior to interim storage.


Penn State-Erie offers one of three undergraduate degree programs in plastics engineering technology in the country, which has seen considerable growth since its inception in 1989. A decision was made recently to increase the chemistry component of the program by adding a course in introductory polymer chemistry. The students have superior practical skills and experience in the handling of plastics, but are poorly equipped to deal with the properties of plastics at the molecular level. A traditional course in polymer chemistry was inappropriate for their needs, so a more visual approach was chosen, based on teaching the fundamentals of organic chemistry using a molecular drawing and modeling software package interfaced with a polymer database, which can predict polymer properties based on their structure. SciPolymer/Alchemy 2000 is a database of 630 compounds, any of which can be drawn in Alchemy, a molecular modeling and discovery program, by a click of the mouse. Students can design a new polymer in Alchemy, import it to SciPolymer, and examine its properties. The graphics are striking, so students are able to see real molecules, both big and small, and learn about their chemistry using Alchemy instead of a textbook.


The aim of the present study is to demonstrate the influence of the spatial nonhomogeneity of the laser beam intensity profile on laser induced breakdown in aqueous medium with the use of optodynamic methods. In the experiment the optodynamic waves were induced with pulsed Nd:YAG laser beam which had several "hot spots". The resulting optodynamic transient waves were detected with two detectors: a laser beam deflection probe inside the liquid, parallel to the liquid surface and a piezoelectric transducer at the bottom of the container. The results of the experiment indicate the existence of numerous smaller waves that are observed before the main signal in the optodynamic wave form, contrary to wave forms generated with a laser beam having a smooth spatial profile.


Abstract Aim: In this study, we aimed to compare the sensory and motor effects of a subanalgesic dose of morphine and morphine + ketamine added to 5% hyperbaric bupivacaine (HB) in unilateral spinal anaesthesia. Methods: 45 patients were randomly assigned to one of three groups. The first group received 1.5 ml 0.5% HB + 0.2 ml saline; the second group received 1.5 ml 0.5% HB + 0.1 ml morphine (0.1 mg) + 0.1 ml saline; the third group received 1.5 ml 0.5% HB + 0.1 ml ketamine (0.5 mg) + 0.1 ml morphine (0.1 mg). Maximum block levels, time to reach that level, time to reach T10 level and block levels after 120 min were recorded. Results: Maximum sensory and motor block levels, time to reach these levels and time to reach T10 level were similar in all three groups, but there was less regression of sensory block level in the third group than in the other two groups. Conclusion: Subanalgesic doses of morphine and ketamine added to 0.5% HB extended the sensory block period but not the motor block in unilateral ...


The Fourier transform f of a function is defind by t ∊ ℝ n . A (ℝ n ) is the isometric image of L 1 (ℝ n ) under the Fourier transformation. We extend the Fourier transformation to a mapping of ℒ(ℝ n ) to itself and denote by A ′(ℝ n ) the isometric image of L ∞ (ℝ n ).


Even though various research has examined the factors that cause visual discomfort in watching stereoscopic 3D video, the brightness factor has not been dealt with sufficiently. In this paper, we analyze visual discomfort under various illumination conditions by considering eye-blinking rate and saccadic eye movement. In addition, we measure the perceived depth before and after watching 3D stereoscopic video by using our own 3D depth measurement instruments. Our test sequences consist of six illumination conditions for background. The illumination is changed from bright to dark or vice-versa, while the illumination of the foreground object is constant. Our test procedure is as follows: First, the subjects are rested until a baseline of no visual discomfort is established. Then, the subjects answer six questions to check their subjective pre-stimulus discomfort level. Next, we measure perceived depth for each subject, and the subjects watch 30-minute stereoscopic 3D or 2D video clips in random order. We measured eye-blinking and saccadic movements of the subject using an eye-tracking device. Then, we measured perceived depth for each subject again to detect any changes in depth perception. We also checked the subject's post-stimulus discomfort level, and measured the perceived depth after a 40-minute post-experiment resting period to measure recovery levels. After 40 minutes, most subjects returned to normal levels of depth perception. From our experiments, we found that eye-blinking rates were higher with a dark to light video progression than vice-versa. Saccadic eye movements were a lower with a dark to light video progression than viceversa.


Based on Bernardo Soares' Book of Disquiet , I will reflect on several issues that I consider central to this work by this semi-heteronymous person: the problem of referentiality; the sense of freedom he finds in the literary sphere; the dialogue (central to this semi-heteronomous person) between the biographical self and the fictional self, taking into account above all the possibilities of reading that they imply on this relationship; the way in which the narrator Bernardo Soares fixes the (re)constitution of a self in the "autobiography without facts" as he himself identifies his Book ; the deconstruction of the autobiographical; the daily complexion that ends up partially determining the process of representation of the Book - not identifiable, however, unilaterally with the indexed record of the empirical reality; its critical positioning in relation to a civilized context "emptied" of respect for each individual; the narrator's search for identity, which seeks to reconstruct himself through the aesthetic-literary vigor with which he constantly digresses on thematic nuclei initialed by anguish, skepticism, uneasiness, unrest; Bernardo Soares' position on literary writing as writing.


According to the requirements of rocket digital convertor's performance,the testing device has been designed and studied.The SCM80C196KB,CPLD and programmable M82C54 counter/timer are the core to realize the testhoard.The detailed design method of each part and the implementation principle are presented.


I conclude with one final observation. We read or hear sometimes that Christianity found in Mithraism its major foe. In retrospect this is how it may seem, but the texts do not bear this out. Even though we possess some polemic passages, in Justin and Tertullian44 for instance, the conflict with Mithraism was astonishingly mild in comparison with the Christian polemic against heresies, Judaism, paganism and the imperial cult. The church did not fight Mithraism on a large scale! We do have signs of conflict: the Mithraea of Fructosus and Santa Prisca were maliciously45 destroyed. But these destructions were done after the threat was over. Whoever broke into


Yellow ampel bamboo is one type of bamboo that has economic value. One effort that can be done for maintaining the existence of bamboo population so that its can be sustainably used through the cultivation of branch cuttings. The success growth of branch cutting can improve with using plant growth regulator (PGR), such as NAA and Rootone F. The aim of this study was to get the best kind and concentration of PGR that can promote the growth of ampel yellow bamboobranch cutting. This study used experimental methods with a completely randomized design (CRD) two factors. The first factor wasthe kind of PGR which consists of two levels: z1 = NAA and z2 = Rootone F. The second factor was the concentration of PGR which consists of six levels: k1 = 0 ppm, k2 = 100 ppm, 200 ppm = k3, k4 = 300 ppm, 400 ppm = k5, and k6 = 500 ppm. Data were analyzed using ANOVA (α = 5%) and to know the difference between treatments used Tukey test (α= 5%). The results showed that the Rootone F had a better effect than NAA on the growth of yellow bamboo branch cutting. Concentration of 200 ppm was the best concentration to the growth for branch cuttings of yellow ampel bamboo. Interaction Rootone F and concentration 200 ppm showed the best result to the growth for branch cuttings ampel bamboo. Keywords :branch cutting, ampel yellow bamboo, NAA, Rootone F


Abstract The approaches to the construction methodology for market segmentation and consumer diagnostics, based on the joint application of multivariate statistical analysis and artificial neural networks. Solution to the problem is proposed to conduct market segmentation using Kohonen self-organizing map and subsequent refinement of the results using the k -means method, and the solution of the consumer diagnostics by using discriminant analysis and multilayer perceptron. The results of the comparative analysis of numerical experiments to address the challenges of market segmentation printed products and diagnostics of the new customer.


On the basis of 1,171 actual IEC (It-Evaluative Construction, i.e., extraposition in traditional grammar) examples from the BNC and other sources, the present paper investigates the interrelationship between the two major semantic elements of the construction, the Evaluator and the Evaluated. It is found that first-order entities never occur in the IEC as the Evaluated; all instances of the Evaluated belong to second or third-order entities. A general correspondence exists between modality and third-order entities and between attitude and second-order entities. That is, all the exponents of modality are directed to third-order entities and an overwhelming majority of attitudinal exponents is oriented to second-order entities, and vice versa. (The 55 exceptions are explainable in terms of relevance of the entity to the text.) Thus, the distribution of the evaluative categories and the evaluated entities and the correlation between them are semantically motivated.


The performance of an optical reflective position sensor is evaluated as the position feedback element in the microposition control of a linear electromagnetic motor. The open loop position sensor characteristics are first measured to determine the analog controller design parameters. The performance of the controller, evaluated using an integrated Michelson interferometer, measures the control loop bidirectional accuracy, hysteresis, long‐term stability, and position linearity. Compensation of the small nonlinearity measured required linearization of the input command signal and a practical application is demonstrated with a constant velocity scan of one of the interferometer mirrors. A final result is the submicron square wave modulation of the interferometer output with its scan mirror under closed‐loop control using feedback from the reflective position sensor.


Finger millet is a food crop that provides nutritional security and is climatically resilient for farming and agricultural diversification. However, its quality and yield remain low due to biotic and abiotic factors, the greatest of which is blast disease caused by Magnaporthe oryzae . We surveyed the occurrence, distribution and severity of finger millet blast in five counties, namely, Busia, Bungoma, Kisii, Machakos and Makueni, in Kenya. Blast disease occurrence was determined by observing disease symptoms of different plant parts on each farm, and symptoms were recorded as either present or absent. Severity was evaluated based on the disease symptoms on plant fingers, leaves and necks and generally at the whole farm scale. Distribution was assessed based on the number of farms sampled for blast per county, and global positioning systems coordinates were recorded. Blast occurrence was 100%, with a uniform distribution pattern on all the farms surveyed across all the counties. Busia County had the highest disease severity at 82.3%, while Makueni had the lowest severity at 61%. Pearson's correlation test revealed no statistically significant correlation between blast severity and plant parts infected (p< 0.05), with Busia (74.2%) having the highest number of plants showing symptoms of blast on fingers, followed by Bungoma (57.1%), Makueni (57%), Machakos (56%) and Kisii, 53.3%. This study reveals that finger millet blast is rampant in all the counties surveyed and is widely distributed in Kenya. This information is helpful in understanding the geographical distribution, occurrence and severity of M. oryzae . The purpose of this study was to determine the duration from planting to reproductive phase, of wild blackberry ( Rubus spp.) collected from the wild. It was carried out at the Horticulture Research and Teaching Farm, Egerton University, Njoro, Kenya. The experimental layout was a randomized complete block design (RCBD) replicated three times; treatments were four wild blackberry species and one cultivated cultivar. The days to first flowering were significantly shorter in cultivated species Rubus fruiticosus at 126 days after planting while wild species Rubus pinnatus, Rubus steundneri, Rubus volkensis and Rubus apetalus took much longer time (341, 333, 332 and 227 days, respectively). Compared to other wild species R. apetalus took a significantly shorter time to flowering than all the other wild species. Analysis also showed that cultivated species , R. fruiticusos had significantly the longest harvesting duration compared to all wild species planted in the present study. It is concluded that wild blackberry species under conventional production practices have varying days to reproductive phase. However, more studies are necessary with a view to reducing the days to reproductive phase for the wild species to compare favourably with the cultivated types. Potato tuber yield and quality is constrained by a number of biotic and abiotic factors, among which low soil fertility is the prime one. Thus, the objective of the study was to evaluate the effects of chemical fertilizer types and rates on tuber yield and quality of potato at Assosa, Western Ethiopia. The treatments consisted of control, three rates of NP combinations (55 kg N and 45 kg P 2 O 5 , 110 kg N and 90 kg P 2 O 5 , 165 kg N and 135 kg P 2 O 5 kg ha -1 ), one NPK combination (110 kg N, 90 kg P 2 O 5 and 69 kg K 2 O ha -1 ), formula 2 (100 % NPSB + 91.9 N kg ha -1 and 200% NPSB + 128.8 N kg ha -1 ) and formula 4 (100 % NPSZnB + 93.1 N kg ha -1 and 200% NPSZnB + 131.2 N kg ha -1 ). It was observed that higher marketable tuber yield (30.03 t ha -1 ) and total tuber yield (34.58 t ha -1 ) were obtained with the application of NPK (110 kg N + 90 kg P 2 O 5 + 69 kg K 2 O ha -1 ) implying that K is an important limiting nutrient besides N and P in the study area. Therefore, NPK fertilizer application is recommended for high yield and quality tuber production in Assosa area, western Ethiopia. Information on the nature and magnitude of genetic variability is one of the prerequisites for a successful breeding program in selecting genotypes with desirable characters. To estimate the level of genetic divergence of lowland rice genotypes, a field experiment was conducted using thirty-six genotypes during 2017 main cropping season. The experiment was laid out 6x6 simple lattice design. Analyses of variances showed significant differences among traits tested, except harvest index. Principal components PC1, PC2 and PC3 accounted for 64.16% of the total variation. The highest inter-cluster distance was exhibited between cluster I and IV (D 2 = 769.77), cluster I and VI (D 2 =485.33), cluster I and III (D 2 =232.35), cluster III and IV (D 2 =312), cluster III and VI (D 2 =197), cluster IV and VI (D 2 =746.51), cluster VI and V (D 2 =259.51) and cluster VI and VII (D 2 =140.15). The crosses between genotypes selected from cluster I with clusters IV, VI and III; cluster IV with clusters III, VI and V are expected to produce better genetic recombination and segregation in their progenies. The cluster means for cluster VI and I were characterized by early heading and early maturity. While cluster I, II, III, and IV were characterized by high mean performance for grain yield for most of its components.


Reaction of MoCl3 and Si at 500 °C produces phase-pure MoSi2 powders in near-quantitative yields. Use of an inert diluent (LiCl or ZnCl2) enables the production of nanocrystalline powders. The diluent can be subsequently removed by washing with methanol or by sublimation. Consolidation of diluent-free powders by hot pressing at 1400 °C and 375 MPa for 0.5−4 h affords dense compacts (>95% theoretical density) possessing nanocrystalline grains (<50 nm) and exhibiting hardnesses of 15.0−16.3 GPa. This constitutes a 60−75% enhancement in hardness over conventional, microcrystalline MoSi2.


Simple questions are sometimes the most profound. And answers to simple questions about exercise sometimes do not exist in print; rather, they are often intuitive to skilled coaches or contained in knowledge that is that is passed on in the lore of the gym rather than recorded in books or formal training programs. Expert coaches, teachers, clinicians, and professors sometimes take it for granted that what we think is basic, simple common knowledge is apparent to all. Recently, during the course of shooting video footage for a DVD project spearheaded by Mark Rippetoe, Rip made a number of comments about arms being short, legs being long, and various and sundry other references to body segments not being of the usual proportions. (Imagine Rip's usual colorful descriptions here.) One particularly humorous comparison of one of our early book models to a Tyrannosaurus Rex made Katie from CrossFit NorCal ask a question: "How do you know someone's arms are longer or shorter than normal?" It was a simple but very good, insightful, and germane question. But it is a question that, as far as I know, is not treated in the exercise literature anywhere. Movement, specifically technical movement in exercise and sport, is subject to anthropometric and geometric influences. This means that how people's bodies are put together and the relative sizes of the various parts affects how they look and perform when doing certain movements. Just think about obvious cases of this truth—NBA centers and NFL offensive linemen, for example. Their build suits the demands of their sport and position, and so the best players in a given physical sport usually have similar dimensions. Soviet sports scientists even had a set of target anatomical dimensions they used in selecting developmental athletes in various fields to increase the likelihood of individual and team success. Championship teams are frequently built by recruiting players with the right bodies and skills—as much as by elite coaching. The average trainer, coach, or physical educator must have a functional understanding of how differing anatomical phenotypes (different body dimensions and body-segment lengths) affects the way proper technique looks. To do this, one must first have a reference point and have a means to mentally and visually comprehend typical segmental relationships. Some of this is intuitive in good coaches, but, as Katie's question makes clear, we also need a more concrete way to determine whether an individual's torso is longer or shorter than average for someone of that height, whether the arms are of average length or not, or whether there is a difference in leg length that is significant to the movement in question. If there is a difference it needs to be localized: Is it in the upper arm vs. forearm, or in the shin vs. the thigh? A savvy coach will have a knack for this determination. It is a handy skill. Being able to see, at a glance, how a trainee's body dimensions compare to an average template helps us place the trainee in correct, efficient, and safe exercise positions. Being oblivious to anthropometric considerations means that we cannot teach our trainees how to exercise to their best benefit for the biggest gain in fitness. Being oblivious means that we may, without intending to, place trainees in positions that can decrease their efficiency and even increase their risk of injury. Fortunately, we do not need to develop a new and elaborate system for doing such an analysis. We can simply take a trip back to the Renaissance to revisit the works of Leonardo da Vinci. Virtually everyone exposed to exercise, anatomy, sport, or da Vinci has seen his drawing of a man in a circle in a square, known as the Vitruvian Man (after Vitruvius, an architect From


Aim: To investigate the influence of a moderate exercise program during pregnancy on the maternal health perception. Methods. A randomised controlled trial was performed. 101 primiparous women were allocated into the control group (CG, n=51) and the exercise group (EG, n=50), lost to follow-up 13, 11.4%. Women on the EC were asked to participate in a supervised exercise program during from 10-14 to 36 weeks of gestation (70-75 sessions, 55-60 min/session, three times per week). Women in the CG received usual care. All women were asked to fill in validated questionnaires about health perception and urinary incontinence before and after the intervention. Results. At the end of the intervention there were statistically significant differences between groups on health perception (very good: EG 35, 70% vs. CG 5, 9.8%; good: EG 15, 30% vs. CG 16, 31%; average EG 0, 0.0% vs. CG 26, 51%; poor EG 0, 0.0% vs. CG 3, 5.9%; very poor: EG 0, 0.0% vs. CG 1, 2% (p<.001)). What is more, women in the EG showed less urinary incontinence (ICIQ-SF Score EG 0.30 (SD1.3) vs. CG 3.1 (SD4.1), p<.001). Conclusions. A supervised physical exercise program during pregnancy which includes pelvic floor muscle training, improves health perception and it is effective on primary prevention of urinary incontinence.


With the continuing demand for Australians to develop second language skills to ensure, in part, the development of cross-cultural understanding, there is a need to examine critically the claim that language learning and cultural understandings are causally related. This paper examines the question of whether cross-cultural competence can exist independently of language expertise, and whether language learning of itself results in cultural tolerance and access to other world views. An examination of existing research, together with an analysis of the popular press in three Australian states, indicates that: (i) the wider community believes that learning a language will result in an understanding of and facility in the target culture; and (ii) languages learned in formal class settings do not necessarily lead to cross-cultural understandings and a lessening of insular cultural attitudes.


Significance Viruses that target the respiratory tract can inflict pulmonary damage, with acute respiratory distress syndrome (ARDS) as a potentially fatal outcome. Neutrophils are key actors in ARDS. Here, we use nanobodies that target Ly6C/G, markers of neutrophils, to image inflammation in the lung and to selectively deliver dexamethasone to the targeted cell population via a nanobody-drug conjugate (NDC) in influenza virus–infected mice. The positron emission tomography imaging data show a clear increase of the Ly6C/G-positive population in the lungs during infection. The NDC prevented weight loss in mice, using but a fraction of the amount of free drug that would be required for treatment.


Abstract: The topic of migration is relevant and significant for society and the state. The legal component of migration, the quality of normative regulation, legal and organizational support for the activities of public authorities in the field of migration, authorized to implement migration policy, do not always correspond to the rapidly developing legal relationship, especially in the context of the coronavirus pandemic. And in this regard, the author identified a number of problems that require their prompt legal solution. The author of the material proposed a classification of executive authorities in the field of migration.
In order to solve one of the problem — the delimitation of powers between the bodies exercising competence in the field of migration policy, as the author notes, individual scientists are invited to develop and adopt a special Federal Law dedicated to the delimitation of such powers. The author focuses on the fact that there is a need to distribute powers between various subjects of migration policy, substantiates the need to identify criteria based on which these powers will be distributed.
In particular, the main body of state power in the field of migration should be, in fact, the Main Directorate of Internal Affairs of the Ministry of Internal Affairs of Russia. Also, it is the Main Directorate of Internal Affairs of the Ministry of Internal Affairs of Russia that should be responsible for coordinating the activities of other state bodies implementing policies in the field of migration.
In conclusion, the author points out that the improvement of state policy in the migration sphere, which is also associated with the strengthening of the law enforcement component of the activities of the subjects of migration policy. Without the interaction of the Main Directorate of Internal Affairs of the Ministry of Internal Affairs of Russia with other federal executive bodies in legal regulation in the field of migration, as well as in the implementation of law enforcement functions for federal state control (supervision) in this area, it is impossible to stabilize the migration situation in the country and ensure the national security of the Russian Federation.


The present study is focused on the development of industrial working-class households' economic life cycle, including income, capital savings, and credits in the nineteenth century. The annual household income was low up to the age of 35 of the head of the household. It then rose and culminated when the head of the household was 55–60 years old. The earnings of other members of the family, foremost the adult sons, being entered on the accounts of their fathers, made the annual income increase higher than the daily wages imply. Credits and savings were used to balance long-term consumption.


The aim of the paper is to derive the equations expressing the static equilibrium of
membrane shells without introducing the bending theory. The first part gives a comprehensive
introduction to the notions of tensor analysis which are needed in the forthcoming mechanical
applications and contains a brief sketch of the background in classical differential geometry.
The derived formulas are illustrated on some simple examples in the last chapter.


The CCD/Transit Instrument (CTI) is a dedicated survey telescope designed to do a deep photometric and polarimetric survey of about 50 square degrees of the sky. This telescope will be used to find variable objects in real-time. The principal scientific programs of the CTI will be the detection of supernovae prior to maximum light, the supernova production rate as a function of galaxy color and redshift, and the definition on the basis of variability and nonstellar color of a sample of QSOs complete to faint limiting magnitude.


This essay contains a reduced form analysis of campaign contributions made by subsidy receiving farmers, in order to better understand if contribution strategies for campaigns in the House of Representatives by individual farmers differ based on whether or not the candidate represents their local congressional district, a non-local congressional district within the donor?s state, or an out of state congressional district. This is accomplished by applying a Tobit model to a panel of contributions, recording zero values of farmers in a given congressional district contribute nothing to a given legislator. Results indicate that farmers appear to contribute heavily to local campaigns regardless of the power of the legislator to influence agricultural legislation, while the ability of legislators to influence agricultural legislation becomes a more important driver of campaign contributions in more distant elections. Key Words: Agricultural Policy, Lobbying, Rent Seeking, Campaign Finance


This article explores the way in which art can illuminate war, in particular the Great War. It focuses on Paul Klee's painting, Angelus novus (1920), and the interpretation of that painting by Walter Benjamin, who owned it, in his celebrated theses �On the concept of history� (1940). Benjamin's interpretation was a kind of parable: he called it the angel of history. Some have taken inspiration from that characterization; others have offered striking alternatives, including Kaiser Wilhelm II and even Adolf Hitler. The article traces the evolution of these identifications; it also considers the continuing artistic response, in historical perspective�notably Anselm Kiefer's The angel of history: poppy and memory (1989). It argues that our conception of the war, and of all wars, is profoundly affected by artistic imagination, and re-imagination.


The use of intelligent systems and technology is very much needed during this Covid-19 pandemic. The reason is that there are many sectors that must be rescued immediately, such as health and the economy. On the one hand, the community must be saved from the ongoing epidemic, but on the other hand, economic activity must continue to be pursued even though it is not in ideal conditions. One solution to these problems is the design of Smart Crowdsensing based on smart services that can be used to support physical distancing but still stimulate economic activity to keep moving. In general, smart crowdsensing functions to (i) detect crowds using location data from the user's mobile device GPS, (ii) self-quarantine surveillance and contact tracing using position history in real time, and (iii) collect and process information from citizen interactions. on social media to find out citizen reports related to the pandemic. Smart crowdsensing is designed using a smart service engineering method that allows it to communicate with other services using a REST API.


During chemical procedure such as permanent and dyeing, etc, chemical remains create active oxygens and cause damages on scalp and hair. Hence, this study is to find out how addition of rose hip which is an antioxidant controlling active oxygen affect hair. After perm procedure by adding 15%, 20% of rose hip to first perm agent and Acid dyeing, hair wave formation, hair thickness, water contents, cuticle, hair microstructure, amino acid creation, color resolution were analyzed and results are as follows. Perm wave formation test results showed A-1 without rose hip addition showed the highest wave formation. The results of water content measurement showed A-3 with acid dyeing after adding 20% rose hip was the highest of 10.46% in group A. The results of tension strength measurement showed A-2 with acid dyeing after adding 15% rose hip was the highest strength of 105.45 ± 29.42 gf/mm2 in group A. The results of tension elongation measurement showedA-3 with acid dyeing after adding 20% rose hip was the highest elongation of 165.54 ± 11.64% in group A. The results of cuticle examination showed that acid dyeing after perm procedure also reduced cuticle damage as adding rose hip, so it was confirmed that addition of rose hip had effects of treatment protecting cuticle layer of hair. The results of amino acid creation analysis showed A-2 with acid dyeing after adding 15% rose hip was the highest of 95.98% in group A. And the results of hair color resolution measurement showed A-2 with acid dyeing after adding 15% rose hip was 3.28 which was the closest color to comparing group. Currently in beauty industry, hair chemical procedure takes significant weights in the market but due to repeated procedures, it is hard to keep beautiful and healthy hair conditions. Hence, it is necessary to continue clinical experiments about hair chemical products which enable to create desired hairstyle without damages on hair.


Abstract : The focus of our Phase I study was to develop and test an algorithm to track a single aircraft of known type using the jump-diffusion method for state estimation. This technique avoids the limitations of conventional state estimation methods (most notably Kalman filtering) in dealing with the discrete state variables (such as target type) and the nonlinear/non-Gaussian measurements encountered in multisensor data fusion problems. The jump-diffusion technique operates by using Monte Carlo simulation to directly sample from the Bayes posterior distribution for the target state. The method is applied to the tracking of a maneuvering air target based on a combination of radar point tracking and optical imagery data. Numerical results show in particular that the aircraft orientation information extracted through the processing of optical images can significantly reduce tracking error relative to conventional point tracking methods. In Phase II we plan to continue the development of the Phase I algorithm by adding the capability to track multiple targets and to perform the automatic target recognition function when targets are of unknown type. (AN)


Scientific meetings of doctors of the State Institute for Advanced Training of Physicians named after V.I. Lenin in Kazan. 119th meeting, March 15, 1930 Dr. L.B.Blitstein. Eye morbidity due to dental disease. The speaker, on the basis of his many years of medical practice in the field of ophthalmology and odontology, cited rich material indicating a close connection sometimes existing between diseases of the teeth and eyes.


Background: PTC is the most common type of thyroid cancer and offers excellent prognosis. However, recurrence PTC remains relatively common, especially PTC with BRAF V600E mutation. PTC is often characterized by RET, RAS or BRAFmutations. RAS, RET and BRAF V600E mutations tend to be mutually exclusive. In this study, we investigated whether these oncogenic driver mutations could propose a molecular classification of PTC into distinct tumor immune microenvironment.
 Methods: Surgical tissue samples from 252 patients with stage I-III PTC consecutively diagnosed between 07/2020 to 08/2021 at Sun Yat-sen Memorial Hospital (SYMH) were sequenced using a panel targeting 18 cancer-related genes. Clinical and genomic data from SYMH cohort was compared with 499 stage I-III PTC patients (PTCs) from TCGA.
 Results: Based on the analysis of the genetic alteration profile from SYMH cohort, 252 PTCs can be classed into three major subgroups, BRAFV600E-(83.7%), RAS-(6.0%), and RET-(3.6%) driven PTCs. These three subgroups covered 93.2% of SYMH cohort and 77.6% in TCGA cohort. (Thyroid peroxidase) TPO status was strongly correlated with BRAF V600E (p=0.003), RET (p=0.005) mutations. Median age of RET- driven PTCs was lower than that of BRAFV600E-, RAS- driven PTCs (p=0.034), which was in concordance with TCGA cohort (p=0.0021). In both cohorts, prevalence of lymph node metastasis in RET-driven PTCs (SYMH, 88%; TCGA, 76%) was higher than that in RAS-(SYMH, 20%; TCGA, 21%) driven PTCs (SYMH, RET vs. RAS, P=0.018; TCGA RET vs. RAS, p <0.001). The TPO positive rates in RET- (p=0.034) and RAS- (p <0.01) driven PTCs were higher than BRAF V600E- driven PTCs in SYMH cohort. In TCGA cohort, RET-driven PTCs had longer disease-free survival (DFS) than RAS- driven PTCs, but not statistically significant. Tumor immune microenvironment study in TCGA cohort revealed a more anti-inflammatory tumor state for RAS-driven PTCs, with decreased levels of pro-inflammatory mediators DC cells, Eosinophils, M1 Macrophages, B cells, and CD4 memory T cells, and increased level of anti-inflammatory M2 macrophages. RAS-driven PTCs also had the decreased level of pro-inflammatory cytokines IL-1, IL-2, IL-12, IL-17, IL-18, IFN-γ, and TNF-α. In contrast, significantly increased level of tumor-infiltrating Tregs was observed in BRAFV600E -driven PTCs (p<0.005). BRAF V600E - driven PTCs had higher degree of NKT cells infiltration than RAS-driven PTCs (p<0.05).
 Conclusion: PTCs can be classified into BRAF V600E-, or RAS-, or RET-driven subgroups with district clinicopathological features and tumor immune microenvironmental differences, which implication for clinical treatment decision.
 Citation Format: Miaoyun Long, Yunfang Yu, Lili Lin, Yue Zhu, Langping Tan, Yisikandaer Yalikun, Wenhao Ouyang, Shuai Ni, Xi Li, Ting Hou, Wenjie Sun, Zhange Chen. Novelmolecular subtypes of papillary thyroid carcinoma (PTC) driven by BRAFV600E-,RAS- and RET-mutations linked to distinct clinicopathological features and tumor immune microenvironment [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5265.