The utility model discloses a blind spot image assisting system, which comprises a rearview mirror main body with a set of drive units connected with the rear portion of the rearview mirror; a detection device and an image photographing device respectively equipped on the rearview mirror main body for photographing images and detecting signal; a sensor circuit connected with the detection device; and a central processor control circuit respectively connected with the detection device, a memory, a key set, an external controller, an alarm buzzer and a display unit for transmitting control signals. Accordingly, the detection device can automatically detect whether a foreign object is close to an automobile. When a foreign object is close to the automobile, an alarm sound signal is emitted to warn the driver to enlarge the angle of the rearview mirror and start the image pickup device, and the foreign object may be displayed on a display in the automobile. Accordingly, the blind spot of the driver can be suppressed to improve the driving safety significantly.


Hybrid recommender systems achieve state-of-the-art performance by integrating several different information sources along with multiple recommendation approaches. Probabilistic Soft Logic (PSL) has been shown to be an accessible and effective means of creating extensible hybrid recommenders [11]. PSL allows users to easily create intuitive models that incorporate background information and capture complex interactions. However these complex interactions can sometimes make PSL models difficult to inspect, debug, and understand. In this paper, we present a generic visual model inspector for PSL, and show how our inspector can be used on a hybrid recommender system to: debug errors in the model, analyze the performance of individual components of the model, and explain recommendations made by the model.


Marine soundscapes are being dominated by anthropogenic sounds, influencing important aspects of animal ecology such as finding a mate. Cetaceans are ecologically important for marine habitats as natural regulators in their web-chains and impacting them may result in a major ecological concern. This work attempts to describe the occurrence of anthropogenic noise along the coast in Bahia State, Brazil, core area for the humpback whales (Megaptera novaeangliae) from the Breeding Stock A. Two sailing boat expeditions were performed in different years for acoustic monitoring. Anthropogenic noise sources, consisted of diverse boat type, such as artisanal fishing, whale-watching and industrial, described from spectrograms and spatially locating them along the coast. Data gathered during 31 cruising days, covering 1400 nm, resulted in 88 recording points. Humpback whale songs were recorded in all points while boat noise was registered in 14 points, placed at the Abrolhos Bank and near Salvador, where is one of the largest ports in Brazil. During all cargo ship recordings (n= 5), humpback songs could not be listened, characterizing masking. These results indicate pristine and disturbed areas inside the core distribution of humpbacks along the Brazilian coast, being important for noise management and conservation policy.


The validity and consistency of data provided by the respondent is ensured by the editing sub-function, Validity rules (numeric vs character, length of a variable, etc.) are applied to ensure that the captured data correspond to the data provided by the respondent, thus allowing for the automatic processing of the reported data in subsequent steps. Methods for detecting suspicious data are used to ensure consistency between variables. These techniques are used to identify units having a behaviour departing significantly from the rest of the population under study.


The literature contains several efficacy studies of extracts from Dillenia indica Linn. (Dilleniaceae). However there are few studies of toxicity.
Objective: To evaluate in pre-clinical phase the systemic toxicity of the ethyl acetate extract of the fruit of D. indica standardized in betulinic acid and administered topically in mice.
Methods: First, mice were divided into: a test-group treated with extract (150 mg/mL), positive control treated with clobetasol (0,5 mg/mL) and a negative one treated with excipient daily for 10 days (N=20, male and female 1:1). The evaluations were related to mortality, aggressiveness, piloerection, diarrhea, convulsions, abdominal contortions, food and water consumption, body and organs-weight, hematological and biochemical parameters. The open field and the grip force tests were performed. With another set of mice, another groups were formed, just like before but including a naive group treated with excipient, being the positive control treated with metoxypsoralen 1% (single doses). Half hour later, mice were exposed to ultraviolet radiation in minimal dose of erythema, being the photosensitizing effect judged 24 h later.
Results: No mortality, aggressiveness, piloerection, diarrhea, convulsions and meuromotor alterations were observed. The average body weight gain was 1.2 ± 0.3 g, liver weight was 1.5 ± 0.1 g, heart (0.14 ± 0.01 g), spleen (0.07 ± 0.01 g), kidneys (0.53 ± 0.05 g). Average of water consumption (223.2 ± 40.3 mL) and food (241.9 ± 27.2 g). The average glycemia was 52.8 ± 5.0 mg/dL, cholesterolemia (91.2 ± 6.9 mg/dL), triglyceridemia (46.6 ± 4.0 mg/dL), serum urea levels (52.8 ± 4.9 mg/dL) and the activity of aspartate and alanine aminotransferase were 27.1 ± 3.8 and 30.7 ± 8.4 U, respectively. The extract induced photosensitivity close to that induced by methoxypsoralen.
Conclusion: Treatment with extract did not cause mortality or other adverse effects. On the other hand, the data indicated a photosensitizer potential for the extract.


Hevea brasiliensis is the most relevant source of natural rubber-based products in the world, and it is mostly found in Southeast Asia. This species is highly functional because its seeds can be utilized as a starting material for many essential applications related to polymer engineering and technology. The main practical compositions are its shell and kernel. The importance of each composition is varied based on the content of each structure. The kernel is predominantly composed of oil, where the oil can be utilized for the production of biofuel and to impart flexibility in many polymer-based composites. Furthermore, the carbon and lignocellulosic contents are heavily represented in the shell of the rubber seed, making the shell useful as a natural resource for carbon-derived applications.


The Parikh-Doering oxidation is an oxidation reaction that transforms primary and secondary alcohols into aldehydes and ketones, respectively.The procedure can be run at temperatures close to ambient (usually 0°C) without formation of significant amounts of methylthiomethyl ether side product.The first step of the Parikh-Doering oxidation is the reaction of dimethyl sulfoxide (DMSO), 1a & 1b, with sulfur trioxide, 2 at 0 oC or room temperature. Parikh-Doering oxidation is widely applied in organic synthesis. Here is an example of Parikh-Doering oxidation's application in Nicolaou cortistatin total synthesis where the reaction transforms the hydroxyl function group into a aldehyde group.


Primary adrenal leiomyosarcomas are very rare tumors that have been reported in approximately 30 cases in literature. This is a case report of a 72 year old man who was diagnosed with a 5.1 cm left adrenal mass. Patient underwent surgical resection and diagnosed with a primary adrenal leiomyosarcoma with two distinct histologic components. Patient did not have any adjuvant treatment and no evidence of recurrence 3 months postoperatively.


The paper investigates the impact of propagation in Ka band quality, by considering the case of clear sky and uniform cloud coverage, up to conditions of rain. The additional attenuation is linked to the probability by focusing in Europe at different latitudes. A layered model is exploited for numerical estimation of both the attenuation and the cloud backscatter in case of uniform cloud coverage.


Process parameters of stone drilling with a small diameter twist drill were used to predict tool wear by means of a machine learning decision tree algorithm. The model links tool wear with features extracted from the force sensor and the main and feed drive current sensors signals recorded under different cutting conditions and different tool wear states. Signal features extracted from both the time and frequency domain were used as input parameters for construction of a decision tree which classifies the tool state into sharp or worn. The model was refined by selecting only the feature sources most important for classification. The best model achieves 90% accuracy in classification and relies only on features of the current signals, which simplifies its implementation in a CNC system for industrial applications. © 2014 The Authors. Published by Elsevier Ltd. Selection and peer-review under responsibility of DAAAM International Vienna.


Hwang and Ku introduced a concept of reparability feature into key distribution protocol.In this paper,the key distribution protocol,proposed by Hwang and Ku,is analyzed.This paper also presentes security problems in Hwang and Ku′s protocol,and furthermore,the argument on whether the protocol has the perfect reparability feature.So,an improved reparable key distribution protocol is proposed in this paper,which solves these security problems.A method,hiding the duplicated event markers,is also proposed and is applied in the protocol to successfully solve the perfect reparability problem.


Study of the methodology of market analysis is a necessary part of the development of a science of marketing. A case study in market analysis is presented to illustrate the actual problem-solving process, rather than just the rationalized reconstruction of the process often reported.


The influence of the wall on flow field, combustion regimes and flame extinction limit of premixed methane/air flames stabilized in the planar channel with heat conducting walls was experimentally investigated. Experimental data were compared with the results obtained in previous theoretical works. The influence of channel walls on gas flow was estimated by using PIV experiments with non-reacting gas flow and compared with the results of numerical simulation.


ABSTRACT Twenty-three shale samples ranging in depth from 5,194 ft. to 13,246 ft. from Gulf Oil Corporation No. 2 Texas State Lease 53034 well and 33 shale samples ranging in depth from 2,185 ft. to 15,592 ft. from General Crude Oil Company/Department of Energy No. 1 Pleasant Bayou well were examined by x-ray techniques to determine the mineralogy of the geopressured zone in the Brazoria Fairway. Both wells have similar weight-percent trends with depth for a portion of the mineralogy. Calcite decreases, and plagioclase, quartz and total clay increase slightly. Within the clays, illite in mixed-layer illite/smectite (I/S) increases and smectite in mixed-layer I/S decreases. Four minerals have distinctly different trends with depth for each well. In the No. 2 Texas State Lease 53034 well, potassium feldspar and mixed-layer I/S decrease, kaolinite increases, and discrete illite is constant. In the No. 1 Pleasant Bayou well, potassium feldspar and kaolinite are constant, mixed-layer I/S increases, and discrete illite decreases. The most important diagenetic change in each well is the transformation of smectite to illite within the mixed-layer phase which occurs according to the reaction suggested by Boles and Franks with A13+ acting as an immobile component (Boles and Franks, 1979). This change begins at calculated equilibrium temperatures of 89° to 92°C. The decrease in calcite and the lack of chlorite in the shales suggest that carbonate, iron and magnesium migrate out of the shale in each well. In the No. 2 Texas State Lease 53034 well, the Boles and Franks reaction is consistent with a steady supply of original mixed-layer I/S during deposition. Potassium feldspar provides K+ for the smectite to illite transformation. The breakdown of potassium feldspar also results in the formation of kaolinite and the increase of plagioclase feldspar which is due to the reaction with Na+ Ca2+ provided by the smectite to illite change. In the No. 1 Pleasant Bayou well, the Boles and Franks reaction is consistent with an unusually high mixed-layer I/S content in the early depositional stages. The source of K+ for the smectite to illite reaction is discrete illite. The breakdown of discrete illite results in both the formation of kaolinite and the increase in plagioclase feldspar.


Mortati's most important and original contribution to the science of law was the concept of «costituzione materiale». The concept was meant to explain the origins and subsequent life of all modern state constitutional systems, by assuming the existence of an original set of distinct constitutional values underlying the formal Constitution, permanently conditioning its developments, and decisive for the correct interpretation of it. The essay, while recognizing the merits of the theory as a step away from the formalistic concepts of traditional positivism, criticizes the concept as inadequate to explain the real facts of the origins and subsequent life of Constitutions, and as misleading as a theory advocating a particular method for the interpretation of the Constitution by the Courts and the jurists. A realistic history of constitutional systems shows that the clauses of a Constitution are usually open to different readings as to the values they incorporate, and that later the readings have always been influenced by sets of new, emerging values. As to the problems of the best interpretation of the formal Constitution in view of its application, Mortati's theory is twice open to objections. If adopted, it is likely to induce the interpreters to read surreptitiously the political values they believe in into the pretended body of values of the «costituzione materiale», indirectly contributing to create a false historic image of the ideas that in fact influenced the adoption of the Constitution. In addition, and more important, it would prevent the interpreters from discussing openly, as they should, the merits of the personal political values they use to read the text of the Constitution and adapt its practical workings to the requirements of justice and the needs of the time.


Many studies reported a high prevalence of undernutrition in the under-5 children in Bangladesh. But very few information are available about undernutrition and adiposity among school children and adolescents in Bangladesh. This study addressed the prevalence of undernutrition and obesity among school going children and adolescents. A total of 15 secondary schools were purposively selected from rural, suburban and urban areas. The teachers were detailed about the study protocol. Then the teachers volunteered to register the eligible (age 10 – 18y) students for the study. Each student's parent was interviewed for family income. Height (ht), weight (wt), mid-upper arm circumference (MUAC) and blood pressure were taken. Fasting blood samples were collected for fasting plasma glucose, total cholesterol (Chol), triglycerides (TG), high-density lipoproteins (HDL). Body mass index (BMI) was calculated (ht/wt in met. sq) for diagnosis of undernutrition (BMI 25.0). A total of 2151 (m-1063, f-1088) students volunteered the study. Of them, the poor, middle and rich social classes were 25.4, 53.1 and 21.5%, respectively. Overall, the prevalence of underweight, normal, overweight and obesity were 57.4%, 35.0%, 4.9% and 2.7%, respectively. For gender comparison, there has been no significant difference of BMI between boys and girls. By social class, the prevalence of underweight was significantly higher in the poor than in the rich (62.2% v. 43.6%) and obesity was higher in the rich than in the poor (6.1% v. 1.2%) [for both, p<0.001]. Logistic regression showed that the participants from urban (OR 1.51, 95% CI 1.03 – 2.22) and the rich (OR 2.03, 95% CI 1.24 – 3.33) social class had excess risk for obesity. The risk for undernutrition was found just reverse. Undernutrition was found most prevalent among the rural students and among the poor social class; whereas, prevalence of overweight and obesity appears to be increasing with urbanization and increasing family income. Thus, the study showed a nutrition paradox – adiposity in the midst of many undernourished children and adolescents in Bangladesh. Further study may be undertaken in a large scale to establish diagnostic criteria for age specific nutrition assessment in Bangladesh. A prospective children cohort may help assessing the cut-offs for unhealthy sequels of undernutrition and adiposity. DOI: http://dx.doi.org/10.3329/imcj.v6i1.14710 Ibrahim Med. Coll. J. 2012; 6(1): 1-8


AECL is collaborating with Argonne National Laboratory in the development of the Hybrid Cu-Cl Cycle for hydrogen production using nuclear energy. This cycle is well suited for integration with the Supercritical Heavy Water Cooled Reactor (SCWR) under development by AECL as part of the fourth generation Advanced CANDU® Technology.


We propose an extension of Haskell's type class system with lambda abstractions in the type language. Type inference for our extension relies on a novel constrained unification procedure called guided higher-order unification. This unification procedure is more general than Haskell's kind-preserving unification but less powerful than full higher-order unification.The main technical result is the soundness and completeness of the unification rules for the fragment of lambda calculus that we admit on the type level.


The photosynthetic pigments, biochemical and enzymatic activities in two freshwater microalgal species, Chlorella vulgaris and Desmodesmus subspicatus at different fluoranthene concentrations were compared with the control conditions. During 16-days of incubation period when treated with fluoranthene, both microalgal species exhibited variable amount of photosynthetic pigment, biochemical compounds and enzymatic activities. The addition of fluoranthene at concentrations ranged from 1.5 mg l -1 ; to 10 mg l -1 ; to microalgal cultures led to changes in all different metabolites but the patterns varied from species to species. Among the two species tested, pigment, biochemical and enzymatic contents were remarkably declined from 7 % to 95% in C. vulgaris . Moreover, all metabolites in D. subspicatus also diminishing significantly by 3% to 88% of fluoranthene doses (10ppm). These results suggest that fluoranthene-induced changes of pigments, biochemical and enzymatic variations in test microalgae, D. subspicatus and C. vulgaris, might reveal its resistance and ability to metabolize PAHs. At the same time, the PAH impact changes on different metabolic activities were higher at 12 and 16 days than at 4 and 8 days in treated microalgae. DOI: http://dx.doi.org/10.3126/ije.v3i1.9941 International Journal of Environment Vol.3(1) 2014: 41-55


This paper presents the results about the mechanical characterization of steel and polypropylene fiber reinforced concrete to be used in industrial ground floor slabs, assessing parameters such as compressive strength, modulus of elasticity, compressive toughness, flexural strength, flexural toughness, flexural residual strength and fracture energy. The characterization plan consisted in manufacturing cylindrical and prismatic specimens of fiber reinforced concrete, including nine types of fibers: five of steel and four synthetic or polypropylene. Also, non-reinforced concrete samples were mixed as a reference, based on a design of 40 MPa flexural strength concrete used for industrial ground floor slabs. Based on the results, it was observed that the shape and length of fibers have influence over flexural strength development and over some other concrete mechanical properties as ductility, since concrete samples made with steel fibers with hooks in its extremes showed a better adherence to concrete, while straight copolymer fiber and wavy polymer fiber showed a better general performance. Finally, it was observed a good correlation between compression toughness values and flexural ones.


To ensure the continuous washing process and good washing effect of tunnel continuous washer,various design models of internal roller were set up by using the software SolidWorks,the advantages and disadvantages of their solutions were contrasted.While determining a design method of bottom internal roller,used the software HyperMesh to 3D model grid the internal roller,with appling static load and related constraints to begin the finite element analysis of the structure.The results show that the stress and displacement cloud map prove that this new structure meets the requirement of strength and rigidity,so it can guide the first national production of bottom transmission tunnel washer.


The real and significant risk of sexual violence in conflict situations must be recognized and whenever possible safe transit provided for unprotected women and children and priority for resettlement in safer locations given to those who are especially vulnerable to assault. The occurrence of sexual violence within conflict situations can and should be anticipated and taken into consideration in the design of camps (in order to avoid adding to the vulnerability of inhabitants) and provision of services within them (including security and law enforcement) capacity to support survivors can be developed among staff within refugee camps in order to respond to specific health needs among those who have been assaulted including pregnancy testing STD treatment and counseling. Advocacy on behalf of victims with community leaders can be undertaken for their social reintegration. Safe spaces can be made available where survivors can talk confidentially. (excerpt)


It is quite necessary to compose the index system by selecting the most representative contents of public art teaching standards and quality based on the classification,filtration and integration of the contents of public art education.And the composing of the index system should be made through making analyses from the education's various aspects,such as theory,practice and skills,taking the all-round development of students' artistic quality as guidance,and following the principles of art education embodying multidimensionality,hierarchy,dynamic and visibility.The index system,the weight of which is determined in accordance with its role in the quality of education,is divided into five high-to-low grades and a corresponding score is given to each grade.The evaluation system includes two major aspects of evaluating teaching effectiveness and student learning outcomes.And the main indicators of teacher evaluation are teaching reform,curriculum and teaching,research and exhibition,and teaching performance,while the evaluation of the students has four aspects of artistic accomplishment,artistic practical ability,artistic activities,and elective courses and participation in the arts community.On the premise of the law of art education,the evaluation should be attended by students,fellow teachers,teaching supervisors and other levels of evaluation,in order to ensure its validity and reliability.


In this article, we start from the samples and the kernel principal component contribution rate adaptive point of view. Our aim is to research that how to choose the initial parameters of the mixed kernel function in comprehensive evaluation of KPCA. To some extent, it will overcome the shortcomings that the kernel function parameter is difficult to determine, and it provides an effective method that KPCA applies to determine the kernel function initial parameter of the multi-indexes comprehensive evaluation. We believe that it will be more widely applied to feature extraction with its advantages appear in specific issues, and makes the evaluation method more and more scientific and effective.


Associating Vazan's environmental sculpture to conceptual art, the authors elaborate on the work in terms of time, archeology and the study of natural phenomena. Biographical notes. Circa 50 bibl. ref.


A real-life data stream usually contains many dimensions and some dimensional values of its data elements may be missing. In order to effectively extract the on-going change of a data stream with respect to all the subsets of the dimensions of the data stream, a grid-based subspace clustering algorithm is proposed in this paper. Given an n-dimensional data stream, the on-going distribution statistics of data elements in each one-dimension data space is firstly monitored by a list of grid-cells called a sibling list. Once a dense grid-cell of a first-level sibling list becomes a dense unit grid-cell, new second-level sibling lists are created as its child nodes in order to trace any cluster in all possible two-dimensional rectangular subspaces. In such a way, a sibling tree grows up to the nth level at most and a k-dimensional subcluster can be found in the kth level of the sibling tree. The proposed method is comparatively analyzed by a series of experiments to identify its various characteristics.


Two new dihydroflavonol derivatives, macarecurvatins A and B, have been isolated from the leaves of Macaranga recurvata(Euphorbiaceaae), along with the known compounds diisoprenylaromadendrin, glyasperin A and broussoflavonol F. The structures of the new compounds were determined on the basis of spectroscopic evidence. Upon cytotoxic evaluation against P-388 cells, macarecurvatin B showed strong activity with an IC50 of 0.83 μM.


Since the German reunification rural areas of the new German Laender are significantly affected by economic and social consequences of the transformation process. Main characteristics of these areas are a low density of population and a lack of infrastructure as well as particularly unfavourable conditions for employment and income outside the agricultural sector partially combined with natural disadvantages for agricultural production and low farm income potentials. During the years 1990 and 1991 rural areas suffered from East-West-migration similar to other areas of high population density. It is provided to shift those priority axes to the advantage of support for rural infrastructure and diversification of agricultural production, which will be financed by the EAGGF-guidance section - during the next period of EC-structural policy (1994-1999). These changes indicate that future assistance for adjustment of agricultural structures and rural development perspectives seems to be more related to the specific conditions of rural areas compared to the last period of the EC-structural policy (1991-1993).


The invention relates to a phase-change energy-storage heat pump water heater, which comprises a compressor, a condenser, a throttling device A and a heat exchanger which are communicated through pipes. The water heater is characterized in that a four-way valve is arranged between the inlet end of the condenser and the compressor, a main check valve and a hydraulic accumulator are sequentially connected between the outlet end of the condenser and the throttling device A, one outlet end of the four-way valve is communicated with the air-cooled heat exchanger, the other outlet end is communicated with the compressor through a gas-liquid separator, the other end of the air-cooled heat exchanger is respectively communicated with a throttling device C, an electromagnetic valve and an auxiliary check valve through a three-way pipe, the auxiliary check valve is connected between the main check valve and the hydraulic accumulator through the three-way pipe, the outlet end of the throttling device C is respectively communicated with the outlet end of the heat exchanger, a throttling device B and a regenerator through the three-way pipe, and the other end of the regenerator is connected between the gas-liquid separator and the four-way valve through the three-way pipe. The invention has the advantages of good energy saving effect and high equipment utilization ratio.


Linear N-benzyl-N'-trityl-α,ω-diamines and N α ,N ω -ditritylpolyamines were efficiently converted into the corresponding N-(1-benzyltetrazol-5-yl)-substituted derivatives upon treatment with benzyl isothiocyanate followed by reaction of the thus-obtained thioureas with azidotrimethylsilane under Mitsunobu reaction conditions.


Bimetallic catalysts have been synthesised based on Jacobsen's C2‐symmetric bissalen ligand. They constitute the first examples of compounds with pseuodo‐C2 symmetry, owing to the presence of two different metal ions. They have been investigated in the ring‐opening of meso‐epoxides by trimethylsilyl azide (TMSN3). Pseudo‐C2‐symmetric [CrIIICo]–bissalen complexes were the best in inducing ee (93–94 %) in the ring‐opened product of cyclohexene oxide by TMSN3 under solvent‐free conditions, whereas a pseudo‐C2‐symmetric [CrIIIMnIII]‐bissalen complex displayed the highest turnover frequency (183 h−1) but induced a lower ee (66 %). A broad substrate scope was displayed by a pseudo‐C2‐symmetric [CrIIICo]–bissalen catalyst: at 0.1 mol % catalytic loading and under solvent‐free conditions, it induced the highest ee to date in the ring‐opened product of a range of different meso‐epoxides by using TMSN3.


Insight: A Quarterly Review of If/'orld Affairs, 19-11. British High Commission, 61-64 Campbell St., Lagos, Nigeria, IS. Nigeria Magazine, 96-99, edt K. Akinsemoyin. Exhibition Centre, Marina, Lagos, IS. Annual sub., 8s; overseas, I IS or $1.00; contains a literary supplement; quarterly. Nigerian Opinion, IV, 1-11. Nigerian Cultural Affairs Society, University of Ibadan, Nigeria; monthly. If/'est Africa, Nos. 2.640-1691. Daily Times, P.O. Box 139, Lagos, IS 6d; weekly.


Internet of Things (IoT) focuses on the IntelliSense interaction between the human, agriculture and the environment. This paper presents a survey on the delay-tolerant technology (DT) in IoT, which is no reliable end to end path and the storewaittransmit mechanism is used to ensure delivery success rate in the case of long delay. DT represents a fairly new networking paradigm that allows interconnection between devices that current networking technology cannot provide. This paper provides an overview of several DT models and discusses typical node mobility models in IoT, including mobility method, data delivery scheme and queue management scheme. Several representative routing algorithms of DT are discussed in detail for different IoT applications with high efficiency and low consumption.


A topographical distribution of Ostertagia spp. lesions in the abomasum of sheep has been observed under certain field conditions which is the reverse of that described by Sommerville (1953, 1954) and also seen by this author to be characteristic of a primary Ostertagia spp. infection. This "reverse distribution" has been demonstrated experimentally under conditions in which a heavy primary Ostertagia infection has been acquired (in the field or artificially) and naturally eliminated; the "reverse distribution" is then characteristically acquired by a challenge infection.


Abstract Background: Thoracic spine paraganglioma precipitating acute stroke is extremely rare. We report a case of a patient with thoracic paraganglioma at high risk for spinal cord compression with recurrent cerebrovascular events. Clinical Case: A 59 year old male was admitted for transient right hemiplegia after recent admission for right lacunar CVA. The patient was noted to have episodes of labile hypertension, sinus tachycardia and paroxysmal diaphoresis. Five days after admission, he developed ataxia with right pronator drift and was treated with intravenous thrombolytics for suspected acute CVA. Incidentally, an 8 cm thoracic paraspinal necrotic mass invading T10 and T11 vertebral bodies with impending cord compression was found on imaging. CT-guided needle biopsy of the mass was performed. Pathology showed an oval and spindle cell neoplasm staining positive for synaptophysin and chromogranin, favoring paraganglioma. Chromogranin A was elevated 472 ng/mL (25 - 140 ng/mL). Plasma free metanephrines were 32 g/mL (n < 57 pg/mL) and plasma free normetanephrines were 7690 pg/mL (n < 148 pg/mL). MIBG scan showed focus of increased uptake at T10 and T11 as well as in the left posterior eighth rib and peri-aortic region. Subsequently, the patient developed acute right leg weakness and dysmetria; MRI brain confirmed acute infarct in the posterior limb of the left internal capsule. Alpha blockade followed by beta blockade was initiated. After approximately 2.5 weeks of alpha blockade, the patient underwent spinal angiogram with tumor embolization followed by successful en bloc tumor resection by neurosurgery and cardiothoracic surgery. Final pathology showed a 7.5 cm paraganglioma which demonstrated some aggressive pathologic features including Ki67 index>20% and 10% focal necrosis. Post-operative plasma free normetanephrines decreased to 568 pg/mL and metanephrines were undetectable. Genetic testing utilizing Ambry Genetics PGLnext panel was negative. Conclusion: A differential diagnosis of paraganglioma should be considered in any patient presenting with recurrent stroke and paraspinal mass. Biopsy should be avoided. Timing of surgical resection to decrease risk of further cerebrovascular compromise is challenging and requires a multidisciplinary approach (1). Locally invasive paragangliomas are rare and are often associated with SDHB mutations; however, a full genetic analysis did not identify any known genetic mutations. Reference: (1) Oak, S., Javid, M., Callender, G., Carling, T., Gibson, C. Management of pheochromocytoma in the setting of acute stroke. AACE Clinical Case Reports 2018 4:3, e245-e248.


Protein tyrosine phosphatase 1B (PTP1B) plays a key role in developing different types of cancer. However, the molecular mechanism underlying this effect is unclear. To identify possible molecular targets of PTP1B that mediate its positive role in tumorigenesis, we undertook a SILAC-based phosphoproteomic approach, which allowed us to identify the Cyclin-dependent kinase 3 (Cdk3) as a novel PTP1B substrate. Molecular docking studies revealed stable interactions between the PTP1B catalytic domain and Cdk3. In addition, we observed that PTP1B dephosphorylates a Cdk3 derived peptide at Tyrosine residue 15 in vitro and interacts with endogenous Cdk3 in the nucleus and cytoplasm of human glioblastoma (GB) cells. Finally, we found that the pharmacological inhibition of PTP1B or its depletion with siRNA leads to cell cycle arrest with the diminished activity of Cdk3, the consequent hypophosphorylation of Rb, and the down-regulation of E2F and its target genes Cdk1, Cyclin A, and Cyclin E1. These data delineate a novel signaling pathway from PTP1B to Cdk3 required for efficient cell cycle progression in an Rb-E2F dependent manner in human GB cells and suggest new therapeutic strategies for treating these tumors.


Abstract: In addition to supplying essential nutrients, it is now well accepted that some food proteins can confer additional health benefits beyond nutrition. Some food proteins act directly in their intact form to elicit physiological effects, but generally peptides resulting from digestion, hydrolysis or fermentation of the protein are considered of the most interest, and these frequently display greater bioactivity than the parent protein. In this chapter we focus on the potential for generation and absorption of food bioactive peptides in the gut and their site of action. The range of reported physiological effects of bioactive proteins and peptides is diverse and we review bioactive proteins and peptides with antimicrobial, immunomodulatory and anti-inflammatory effects, their potential mechanisms of action and applications to human health.


How to cite this article: Mazzeu JF, Krepischi-Santos AC, Rosenberg C, Szuhai K, Knijnenburg J,Weiss JMM, Kerkis I, Mustacchi Z, Colin G, Mombach R, Pavanello RM, Otto PA,Vianna-Morgante AM. 2007. Chromosome abnormalities in two patients with features ofautosomal dominant Robinow syndrome. Am J Med Genet Part A 143A:1790–1795.


The aim of this paper is to describe and analyse some of the newly adopted words in Swahili in the field of Information and Communication Technology (ICT).2 This paper should be seen as an attempt to illustrate and classify how new concepts are dealt with in Swahili. It also provides a wordlist of approximately 200 entries and their sources. The report is by no means exhaustive.3 The words and phrases recorded here are either found in existing material and then verified by a speaker, or elicited from more than one speaker, and represent what is actual currency rather than a comprehensive study including low-frequency words and phrases. The relevance of this wordlist lies in its in-depth treatment of presently used words and phrases, not least as a complement to the many glossaries, where the lexemes listed are what experts believe ought to be used, although this does not necessarily reflect 'real life'. Most of the material presented below has been sourced from the internet and supplemented by recent publications, such as the telephone operator Vodacom's quarterly magazine. The bulk of the data derives from Tanzania, but some of the internet sites originate from different countries such as Italy and the United


Objective To investigate the influence of chemotherapy after radical surgery for gastric cancer on the T cell subsets and NK cells in peripheral blood in order to understand the influence of chemotherapy on body immune function and investigate the importance and necessity of the chemotherapy.Methods Thirty-two patients receiving chemotherapy after radical surgery for gastric cancer from June 2007 to June 2010 of our hospital were selected as the observation group and 32 healthy examinees were selected as the control group.The changes of T lymphocyte subsets including CD3+ T cells,CD4+ T cells,CD8+ T cells and CD4+/CD8+ and NK cells in peripheral blood of the two groups were detected respectively.Results Of the 32 patients receiving chemotherapy after radial surgery for gastric cancer,complete remission(CR) was found in 17 patients,partial remission(PR) in 8 patients,no change(SD) in 5 patients and progress(PD) in 2 patients,with the total effective rate of 78.1%(25/32).The observation group was significantly lower than the healthy control group in the CD4+ T cells,CD4+/CD8+ and NK cells before the chemotherapy after radial surgery for gastric cancer.The CD4+ T cells,CD4+/CD8+ and NK cells significantly increased after 3 cycles of chemotherapy after radial surgery for gastric cancer compared with those before chemotherapy(P 0.05).Conclusion Chemotherapy after radial surgery for gastric cancer can improve the clinical efficacy for patients,whose immune function remarkably decreased compared with normal people,and can improve the expression levels of CD4+ T cells,CD4+/CD8+ and NK cells.


To explore the long‐term effectiveness of rufinamide in managing Lennox–Gastaut Syndrome (LGS), other epileptic encephalopathies, and intractable focal epilepsies in adults and children in routine clinical practice.


Flipped Classroom (FC) is a teaching learning methodology that applied the Information and Communication Technology, and where the traditional activities perform by the students were invert with the activities that they do out of classroom. The aim of this work was to implement and evaluate the Flipped Classroom methodology in a unit of the Clinical Haematology course of Medical Technology career in Universidad Santo Tomas, Santiago de Chile.The sample of this study was constituted by 28 students registered in Clinical Haematology course in 2015. To evaluate the FC methodology, we applied a satisfaction survey to the students and the impact of the methodology was evaluate respect of learning of the students.According to results obtained in the survey, 65 % of the students preferred FC instead of the traditional classes and 60 % said that they learned more when FC was used. Respect to the qualification of learning tackled with this methodology, there was observed an increase of 5 % compared with the students of the previous year, nevertheless the comparison of global notes are not statistically significant (p>0,5). In the comparison, the number of students whom obtained more of a 4,0 in their qualification in the test respect at 2015, the difference was statistically significant (p<0,5). In the analysis of the learning evaluated in this study, it was observed that it improves the academic yield of most of students.The FC methodology was satisfactory evaluated by the students and it could be a strategic to improved  their academic performance in this or other classes


Silver-zinc phosphate glasses with heavy metal oxides were prepared in three composition series (WO3, MoO3, TeO2). Structure of glasses was studied by Raman spectroscopy and MAS NMR. Basic physico-chemical properties of the glasses (density, molar volume, chemical durability) were measured. Thermal behaviour of the glasses was studied using DSC, thermodilatometry and heating microscopy. From DSC, TD and HSM curves the values of glass transition temperature, dilatometric softening temperature and thermal expansion coefficient were determined.


The restriction of tidal flow to salt marshes, a common phenomenon in densely populated coastal areas, leads to marked changes in the hydrologic regime of the marsh, which can in turn pose water quality problems both within the marsh and for the larger estuary. We have found significant differences in marsh chemistry and water quality between a tide-gated (restricted flow) marsh and a nearby, unrestricted reference marsh. During the summer of 1995, the desiccation of the restricted marsh due to operation of the tide gate led to a disconnection among the sediments, the small drainage ditches, and the main channel. This allowed dramatic changes to take place in sediment chemistry, including lowered alkalinity and elevated nutrient levels. Re-connection of the sediments with the surface water as a result of rainstorms led to two episodes of severe acidification (pH 3−4) as well as to increases in surface water nitrogen concentrations. Clean-technique trace metal measurements showed that the acidic conditions...


A promising approach to improve the engineering current density of coated conductors is to increase the thickness of the YBa/sub 2/Cu/sub 3/O/sub 7-x/ (YBCO) layer. In this framework, a study regarding the relationship between the thickness of the superconducting film and its critical current was performed on biaxially aligned YBCO films grown on epitaxial Ce/sub 2/O/NiO structure using Ni/sub 89/V/sub 11/ non-magnetic substrate. The critical current density (J/sub C/) was measured for a series of YBCO films with thickness ranging from 0.2 to 2 /spl mu/m, deposited at constant rate. J/sub C/ values up to 6.4/spl times/10/sup 5/ A/cm/sup 2/ at 77 K and zero magnetic field were obtained for thinner films decreasing three orders of magnitude for the 2 /spl mu/m thick YBCO film. X-ray diffraction and morphological analyses indicate a progressive structural deterioration with the increase of film thickness.


The focus here is the letters and unpublished journals of Dorothy Wordsworth, concentrating on the period of her first serious illness, situated next to Virginia Woolf's attempts at pathography. Under consideration is a selection of Woolf's diaries; her essay 'On Being Ill'; her biographical-critical essay on Dorothy Wordsworth published in the second Common Reader in 1932; and her 'biography' of Elizabeth Barrett Browning, Flush, published in 1933. In selecting certain women to write about during the late 1920s/early 1930s, Woolf is extending her project of rethinking and retheorising life writing, particularly in the context of her interest in the subjectivity of illness. At stake is the question of how the lines of a writing life are shaped by illness; how writing renders a transgressive space beyond the 'normal' rhythms of life in which to work through a subject's altered relation to her mind and body; and the ways writing can be restorative for a subject grappling with how she has been othered within the context of her most intimate relationships and everyday life.


American preference for a more flexible conventional and nuclear response is a difference based not on misperception but on conflicting interests defined by geography. One suspects that interest rather than perception (while the latter may influence the former) will prove the more effective analytical tool in any full accounting of alliance differences. To stress continuity is to minimize change. For Grosser, the only important change is change in alliance structure. That structure changed only between 1947 and 1949 when Germany and Italy joined with the West and the Soviet Union shifted from ally to common enemy (p. 322). By defining change in this way, Grosser misses the opportunity to explore and explain the many changes that have taken place within the existing alliance structure. Because Atlantic boundaries have always been broad and flexible, changes that have taken place within the framework of the alliance often have been as important as changes in the framework itself.


The prevalence of overnutrition in Indonesia is increasing from year to year. Overnutrition occurs because of an imbalance between consumed and expended energy. Overnutrition needs a serious attention because it deals with a variety of health problem complications in adult, such as diabetes and heart disease. This research aims to analyze the association between the amount of pocket money and breakfast habit with overnutrition status in elementary school children. Analytical observational research with cross sectional design was conducted in SDN Ploso I-172  T ambaksari Surabaya. The sample size was 52, which was taken by using simple random sampling technique in 4th and 5th grade students. Association among variables were analyzed using Chi-Square test. The result showed that  32.7% of respondents skip breakfast. The mean of respondent's pocket money was IDR 5.894,23 ± 3.215,06. Majority of respondents were obese (34.6%) and overweight (28.8%). Chi-Square test showed there was an association between the amount of pocket money (p=0.000) and breakfast habits (p=0.005) with overnutrition status. It can be concluded that the amount of pocket money and breakfast skipping habit contribute to overnutrition status in elementary school children. Parents are responsible for providing foods with adequate nutrition for children, habituate children to have breakfast at home, and provide pocket money to children with amount less than IDR 5.894,23 ± 3.215,06. Keywords: breakfast, overnutrition status, pocket money


Animal models play a critical role in diabetes research, aiding in the comprehension of both type 1 and type 2 diabetes pathogenesis and the assessment of potential therapeutic interventions. These models offer numerous advantages, including the ability to induce stable hyperglycemia and hyperlipidemia, minimal variability, and the opportunity to study genetic mutations and single gene effects. However, they also present limitations such as lengthy induction periods, fluctuating glucose parameters, potential toxicity to other organs, and high costs. Various screening models, encompassing in vitro assays and models like Alloxan-induced and Streptozotocin-induced diabetes, serve as valuable tools for investigating diabetes and testing drug efficacy. The selection of an appropriate model requires careful consideration of specific research objectives. Despite their limitations, animal models continue to be indispensable for advancing our understanding of diabetes and developing effective treatments.


After the intravenous injection of 100 ml of iodinated contrast agent (350 mg/ml, rate 4 ml/s), a multislice computed tomography (CT) scan was performed using the 64 slice Brilliance multidetector computed tomographic scanner (Philips Medical Systems, Best, the Netherlands): 64 0.625 mm collimation scanner, gantry rotation speed 0.4 s/rotation, minimal slice thickness 0.67 mm. It revealed a 9 cm long sacciform aneurysm of the main pulmonary artery extended to the left branch. No evidence was found of thrombi in the pulmonary artery system (Figs 1 and 2).


In the present paper, we give numerical solution of the Falkner-Skan equation for the study of two-dimensional magnetohydrodynamics steady boundary-layer viscous flow over a wedge in the presence of non-Newtonian power law fluid which is represented by a power-law model. The outer free stream velocity is defined in the form of a power-law manner i.e., it varies as a power of a distance from the leading boundarylayer. The governing nonlinear boundary layer equations have been transformed into a third order nonlinear Falkner-Skan equation through similarity transformations. This equation contains four flow parameters that is the stream-wise pressure gradient (β), the magnetic parameter (M), and boundary stretch parameter (λ), and non-Newtonianpower-law fluid (m). The governing equations (nonlinear partial differential equations) have been converted to an equivalent nonlinear ordinary differential equation along with boundary conditions by means of similarity transformations which is solved using the Keller-box method. A far-field asymptotic solution is also obtained which has revealed oscillatory shapes when the flow has an adverse pressure gradient. The results show that, for the positive pressure gradient parameters, the thickness of the boundary layer becomes thin and the flow is directed entirely towards the wedge surface whereas for negative values the solutions have very different characters. Also it is found that MHD effects on the boundary layer reduce the boundary layer thickness.The results are obtained for velocity profiles and skin friction for various values of physical parameters and are discussed in detail. It is also found that the drag force is reduced for dilatant fluids compared to pseudo-plastic fluids. The Physical significance of the flowparameters are also discussed in detail. Key wordsBoundary-layer equations; Non-Newtonian power-law fluid; Magnetohydrodynamics; Moving wedge; Falkner-Skan equation; Numerical solution; Asymptotic solution; ——————————  ——————————


This study employed ethnographic fieldwork building on cultural theory and dramaturgy to examine and explore a major celebratory event that takes place in a rural community in southwest Texas as a consolidating device for building, reconnecting and strengthening the community's social fabric. The event blends sport with other performance elements. Results show that the community creates a symbolic social space characterized by identification with local history, heritage and values/beliefs and a sense of community reconnection, as well as acknowledgement and recognition. The organic interrelatedness of these mechanisms, enhanced by the sport and theatrical elements present in the event, facilitates the regeneration and reinforcement of a heightened sense of community and a strengthening of the community's social capital. Furthermore, VFR (visiting friends and relatives) tourism is fostered as former citizens of the community are targeted to attend this celebratory event, including the timing of other significant activities, such as when they visit the community for school reunions, which are typically scheduled to occur during the same time period. Implications for sustainability of events in community and tourism development, as well as the role of dramaturgy, are discussed. The dramaturgic nature of the event enables its significance for tourists, particularly former residents, which thereby contributes to the event's value to the community and its consequent sustainability.


Pollution sources census and monitoring is one of the most important work in environment protection and management, which means a lot to environment planning and macro-control. Firstly, this paper analyzes the characteristics of pollution source census data and points out the similarity and common problems of existent environment information systems. Then proceeds to build a pollution sources census oriented management information system based on GIS and spatial database, which combines pollution sources information acquire and management, intelligently query and index, spatial analysis and comprehensive application all together. Finally this paper introduces the specific application of pollution sources census management information system according to the requirements of environment management.


Lori L. Taylor debunks several popular beliefs as she examines how property values relate to taxes, government services, and government debt. She finds that, contrary to popular belief, property values do not necessarily decrease when local governments increase taxes to pay for services. Her analysis reveals that taxpayers value all types of government services, including transfer payments such as welfare and health services. Taylor's work also suggests that people do not automatically prefer deficit spending to tax increases.


I examine the timeliness of write-downs taken by U.S. financial institutions during the financial crisis of 2007–2008. The timeliness of write-downs is measured by benchmarking the quarterly accounting write-down schedule with the devaluation schedule implied by exposure-specific credit indices such as the ABX. The results show that the accounting write-downs are less timely than the devaluations implied by credit indices. In a cross-sectional analysis of the determinants of the timeliness of write-downs, I document that corporate governance quality, regulatory investigations, and litigation pressure are positively related to the timeliness of write-downs, whereas the write-downs by firms with higher financial leverage, tighter regulatory constraints, and more complex exposures are less timely. I control for numerous exposure-specific characteristics and document that less risky exposures and exposures that were affected later during the financial crisis were written down later. Regarding the consequences of timeliness, I find that the exposure to risky assets is reflected faster in stock returns for firms with timelier write-downs.


La modified γ-Al2O3 support samples were prepared by sol-gel method under the action of a pulsed electromagnetic field(PEMF).The physical properties and thermal stability of samples concerned under PEMF were studied and characterized by N2 physisorption,scanning electron microscope,IR spectroscopy and X-ray diffraction techniques.Results show that the specific pore volume and specific surface area of La modified γ-Al2O3 sample with PEMF are increased by 40.0% and 23.7% respectively as compared with γ-Al2O3 sample.Moreover,the amount of surface hydroxyl group covered on the surface of support increases because of evenly dispersed La compounds,and the high temperature thermal stability of samples treated by PEMF has been improved accordingly.


The ASON is a typical client-server network model. Via explicit interfaces between client network and server network, the client users, including UNI-C and NMS, can create an Optical Layer Connection with three schemes. This may arise the problems such as concurrency due to simultaneously accessing the same resources from UNI and NMI. This paper proposes an approach of a middleware component using CORBA-based product. The middleware component performs to define the ownership and access rules for network resources and prove global network topology and status of the network resources to the client users. It screens the difference between NMI-T, NMI-A and UNI and shields the detail of the ASON network protocols. The standardized IDL interfaces ensure that ASON products from different vendors or employing different technologies can interoperate at the common intermediate plane level and make the implementation of the management functions more simply and efficiently.


The criminal act of forgery stipulated in Chapter XII Book II Criminal Code on forgery, the book lists that are included falsification only form of writings alone, including forgery under Article 263 paragraph (1) of the Criminal Code, which reads: "Whoever makes the letter false or forged which can cause something right, commitment or debt relief, or which is applied as proof of the thing with intent to use or get someone else to wear the letter as if it was true and not doctored, threatened that if the use can cause losses, because of forgery, with a maximum imprisonment of six years.As for the purpose of this study include: First, to know the process of investigation in uncovering the crime of counterfeiting Letter Deed of Sale and Purchase of Land in the area of police resort city of Pekanbaru, second, to determine the obstacles investigators in addressing the Crime of forgery Deed of Sale and Purchase of Land in the region police resort city of Pekanbaru, Third, to determine the investigators efforts in addressing the Crime of forgery Deed of Sale and Purchase of Land in the resort city of Pekanbaru police.This research is a sociological research that want to see the correlation between law and society. This research was conducted in the city of Pekanbaru Police Resort, both the population and the sample was also conducted in the city of Pekanbaru Police Resort. In this study the data source used, primary data and secondary data, the data collection techniques in this study with interviews, and a review of the literature.From the research problem there are three main things that can be inferred First, the implementation of the investigation in uncovering the crime of falsification of the Deed of Sale and Purchase of Land in the area of police resort city of Pekanbaru, Second, barriers to investigators in overcoming the crime of counterfeiting Letter Deed of Sale and Purchase of Land in the area of police Resort City Pekanbaru, Third, investigators efforts in addressing the crime of forgery of the Deed of Sale and Purchase of Land in the resort city of Pekanbaru Police. Suggestions Author, First, activity implementation investigation Police Pekanbaru City should be improved so that the investigation can be carried out quickly done, Second, should the City Police Pekanbaru should cooperate with relevant parties such as the National Land Agency of Pekanbaru and the investigator should be more assertive in dealing with criminal offenses of forgery Deed of Sale and Purchase of land, Third, should the type of letter should be reduced, because of the many types of land documents at this time would make it easier to manipulate the perpetrators of the land documents.


Trabeculectomy and its various modifications have been the 'gold standard' in the management of glaucoma. However, the risk of sight-threatening complications has remained unacceptably high and some have questioned the belief that trabeculectomy is the best form of treatment for glaucoma. In black Africans, there is the additional problem of a higher tendency for trabeculectomy failure. Compliance with medical therapy is poor. Lasers are expensive and not readily available. Nonpenetrating glaucoma surgeries have been reported to be less effective than trabeculectomy but with a better safety profile. However, the skill for these procedures is not yet readily available in Africa. Tube shunt and cyclodestructive procedures are available for refractory or complicated cases. Newer techniques such as canalostomy are being developed. Further research to find a new surgical procedure that is inexpensive, effective, long lasting or permanent, as well as rapid and simple to perform, is required to tackle the problem in sub-Saharan Africa.


The invention discloses honey Shatian pomelo tea which comprises the following raw materials: 15-25% of Shatian pomelo (the ratio of skin to pulp is 1-2:2-1), 20-40% of rock candy, 15-35% of high fructose corn syrup, 3-10% of honey, 0.5-1.5% of citric acid, 0.1-0.2% of malic acid, 0.1-1% of a thickener (the ratio of CMC to carrageenan to pectin is 1:1:1), 0.1-1% of brown sugar and the balance of water. The invention further discloses a preparation technology of the honey Shatian pomelo tea. The honey Shatian pomelo tea, prepared through the method disclosed by the invention, is sour, sweet and delicious, and mellow in flavor, retains faint scent of the Shatian pomeloes, is golden yellow, bright and natural, contains no corrosion remover, essence or pigment, is a popular health food at present, and has better market potential.


Parkinsonian syndromes with encephalopathy after heroin abuse are rare. We report a 41-year-old Caucasian woman presenting with symmetric akinetic-rigidic parkinsonism. Twenty-four hours after snorting heroin, the patient exhibited a generalized dyskinetic syndrome and impaired vision, and severe parkinsonian symptoms developed within 2 weeks. The akinetic-rigid syndrome showed good …


Several structural control techniques such as passive, active, semi active and hybrid control techniques are gaining importance in earthquake resistant design of structures. Friction damper is a passive type energy dissipating device, which dissipates the seismic energy by virtue of the solid friction developed between the two sliding surfaces. Friction dampers get activated at their slip load and starts dissipating energy. The maximum energy dissipation and least response of the structure occur at optimal slip load of friction dampers. In the present study, the optimal slip load of the friction dampers provided in a nine storey reinforced concrete frame model was evaluated analytically using nonlinear time history analysis. Then the effect of friction dampers on the displacements and forces in the structure was evaluated. Acceleration time histories of El Centro ground motion (N-S component) and Indian seismic zone IV were used for the analysis. The analyses were carried out using SAP2000 computer package. The results confirmed that a good reduction in the displacements and forces is possible with the addition of friction dampers and hence it can be used as an alternative for the conventional ductility based design methods.


according to C, falls into still more grievous error when he asserts that the divinity of Christ is identical with His unique and pre-eminent humanity. Assertions such as these, in C.'s opinion, run afoul of the teaching of Chalcedon regarding the nonidentity of the divine and human natures in Christ. "In Christ the duality of the human and the divine cannot be resolved by reducing everything to unity, and, in particular, cannot be resolved by denying the true personal divinity of the Savior" (pp. 287-88). Chalcedon, moreover, declared that Christ is consubstantial with us ac cording to His humanity. Thus His humanity does not, as Hulsbosch seems to assert, constitute a new and higher stage of evolution beyond the rest of the human species. In this learned, clearly written, and informative work, C. admirably accomplishes what he has set out to do. If there is any weakness, it is per haps a failure to expose his own methodological assumptions and to bring them into confrontation with the assumptions of his adversaries. To do this, C. would have to go beyond his self-imposed limits and deal directly with the teaching of Scripture and the magisterium. In point of fact, he does appeal to the magisterium against the Dutch theologians. He cites Chalcedon and, on several occasions, Vatican II. For C, the Christology of Vatican Π is contained in Dei verbum. With his lack of sympathy with secular theology, he not surprisingly overlooks the Christology of Gaudium et spes, although this Constitution, in articles 10, 22, 32, and 45, has much to say about the Incarnate Word as revelation. A further limitation is C.'s failure to treat the work of Teilhard de Chardin, which has surely been a major influence on many contemporary Catholic theologians. C. seems to fear that the high Christology of traditional Catholicism might be im periled by concentration on the secular and cosmic dimensions of revela tion. But it is at least equally possible that attention to these dimensions might actually reinforce the traditional doctrines of the divinity and universal lordship of Christ. In any event, here is an issue that C. might have discussed more explicitly in this admirable and helpful work.


E-Passport or Electronic Passport is comprised of a microprocessor chip which contains biometric data used to authenticate the identity of passport holder. Facial image, fingerprint image and palm-print image are some of the currently standardized biometric modalities, embedded in the E-Passports. The privacy of the biometric data becomes a problem during storage and transmission. The biometric data cannot be revoked or re-issued unlike tokens or passwords, if compromised. The possibility of producing cancelable templates from the biometric features of user has been studied, thus eliminating threats to privacy and security of the biometric features. Cancelable template is obtained from original biometric image after intentional/repeated distortions (based on user-specific key), and thereby providing security to the templates. The distortions can be implemented either at signal or at feature level. The cancelable templates can be revoked or re-issued whenever required just by changing the user-specific key. The probability of applying cancelable transformations to secure the privacy of the biometric features in E-passport has been explored in the article


Modeling impacts of management alternatives on soil carbon storage of farmland in Northwest China F. Zhang, C. Li, Z. Wang, and H. Wu State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, CAS, Xi'an, 710 075, PR China Institute for the Study of Earth, Oceans, and Space, University of New Hampshire, Durham, NH 03 824, USA Graduate School, Chinese Academy of Sciences, Beijing, 100 039, PR China Received: 16 January 2006 – Accepted: 3 March 2006 – Published: 16 May 2006 Correspondence to: C. Li (firstname.lastname@example.com)


: Yuan Deyu is one of the founders of the ″Northeastern School″ of Chinese philosophy of technology and has proposed the ″ technology form theory″ and ″technology as process″ as key ideas for understanding technology in the Chinese context. This is the second time that Yuan has been interviewed by Carl Mitcham, one of the greatest living Western philosophers of technology. In the first interview, published in 2018 in the same journal, Yuan recounted how and when the Chinese philosophy of technology originated from the very beginning, in what kind of context it developed and what its current dilemma, etc., based on his own engagement, correcting some of the current discussions about Chinese philosophy of technology among scholars both Chinese and Western, such as whether there should be an empirical turn for Chinese philosophy of technology or does it originated from a book or article, etc. In order to have a comprehensive understanding of both him as an important Chinese philosopher of technology and Chinese philosophy of technology, in this interview, we followed up with further questions of a more personal character, especially about his life. As we all know, a person′s life experience will have a great impact on how he perceive the world. In the beginning, Yuan recalled his personal growth, family background, and work experience, which provide a broad context for contemporary philosophers of technology to better understand the unique characteristics, themes, and methods of Chinese philosophy of technology. He shared his memories of how his acquaintance with Chen Changshu grew into close friendship. They co-authored many books and articles to call for independent academic attention to technology, which turned out to promote the development of Chinese philosophy of technology and determined the characteristics of Northeastern school. He also highly praised Chen's monograph, "Introduction to Philosophy of Technology." Yuan pointed out that his thoughts on technology were primarily influenced by the research of Japanese scholars on technology theory, which is why he preferred to classify his research in the field of sociology of technology rather than philosophy of technology. He recalled the various academic efforts he had made with a group of scholars in the 1980s to promote technology as an independent research object, reconstructing the complete historical development of early Chinese philosophy of technology. Additionally, he also brought attention to the morphological differences between ancient China and the West in expressing human understanding of nature, based on scientific formality. He illuminated the fact that ancient China primarily emphasized practical, empirical knowledge about natural phenomena. In his view, Confucian philosophy has had a profound impact on the development of Chinese technology due to its constraints on research themes within ancient Chinese society.


Given a closed subspace S of a Krein space H and a bounded selfadjoint operator W acting on H, a representation of the shorted operator of W to S is obtained under weak complementability hypothesis.


AGE -RELATED CHANGES IN TWO MUSCLE ENZYMES OF THE HAWK MOTH, MANDUCA SEXTA Connor McMahon Director: Bernie Wone, Ph.D. Aging has been associated with significant declines in muscle strength and mass. The specific molecular mechanisms behind these changes, however, are not well known. One potential mechanism behind muscle aging could be enzymatic dysfunction. This research examines the enzyme changes that occur in the dorsolateral flight muscles of the hawk moth. The hawk moth, Manduca sexta, is an excellent model of muscle aging due to its short lifespan, ease of rearing, and endothermic flight muscles. We assayed citrate synthase (CS) and β-hydroxyacyl-CoA dehydrogenase (HADH) to determine the activity of the tricarboxylic acid cycle and fatty acid oxidation, respectively. A significant change in HADH activity was observed in male hawk moths between daytime and nighttime, but this change was not detected in females. Significant changes in CS activity occurred between middle aged and aged female hawk moths. Overall, CS activity increased with age for females, and aged females showed less distinction between daytime and nighttime CS activity. Increases in CS activity suggest age-related TCA cycle dysfunction in female hawk moths. This research identifies how beta oxidation and TCA activity change differently for male and female hawk moths via aging.


Defect source reduction in leading-edge iArF resists is a critical requirement to improve device performance and overall yield in lithography manufacturing processes. It is believed that some polar polymers can aggregate and be responsible for single or multiple micro-bridge defects. Further investigation into the formation of these defects is needed. We have previously presented the effective removal of gel-like polymers using nylon media [1]. However, as the industry is moving to smaller feature sizes, there is a need to further improve the defect removal efficiency. In this paper, a filter, comprised of a novel membrane called Azora with unique morphology and high flow performance is introduced. This new filter shows better on-wafer in an advanced ArF solution than conventional Nylon and UPE media. In addition, it shows improved stability during chemical storage. Results and possible retention mechanisms are discussed.


Yttrium doped hydroxyapatite nanocrystals were synthesized by sol gel method for three different concentrations of yttrium (3%, 6% & 9%). XRD was used to examine structural parameters, SEM was used to examine surface morphology, and EDS was used to determine the elemental composition. XRD revealed that the crystallite size was 28 nm. When XRD data is compared to JCPDS data, the strength peaks from XRD data are found to be similar. Space group of the grown samples has been found to be P63/m. From the FTIR analysis the presence of HPO4 –was confirmed which reinforces that HAP was synthesized.


Background— Early ART and virological suppression may impact on evolving antibody responses to HIV-infection. We evaluated frequency and predictors of seronegativity in infants starting early ART. Methods— HIV-antibody results were compared between two of three arms of the Children with HIV Early Antiretroviral Therapy (CHER) trial: HIV-infected infants aged <12 weeks with CD4 ≥25% randomised to early-limited ART for 96 weeks (ART-96W) or deferred ART until clinical/ immunological progression (ART-Def). HIV-infection was diagnosed by DNA PCR and RNA >1000 copies/ml. ART started at median age 7 and 23 weeks respectively. Antibody was measured from all available stored samples, ART-96W (n=109) and ART-Def (n=75), at trial week 84 (median age 92 (IQR 90.6–93.4) weeks) using 3 assays: 4 th generation EIA HIV-antigen/ antibody combination; HIV-1/2 rapid-antibody test and quantitative anti-gp120 IgG ELISA. Findings— More ART-96W were seronegative than ART-Def by EIA (46% versus 11%, p<0.0001) and rapid-antibody test (53% ART-96W versus ART-Def (median 230 (133–13,129) versus 6,870 (IQR 1,706–53,645)μg/μl). Starting ART between 12-24 versus 0-12 weeks increased odds of seropositivity 13.7-fold (95%CI 3.1-60.2). All children starting ART aged >24 weeks were seropositive. Cumulative viral load to week 84 correlated with anti-gp120 IgG levels (coefficient=0.54, p<0.0001) and increased odds of seropositivity OR 1.58 (95%CI 1.1-2.3) adjusted for ART-initiation age. Interpretation— Almost half children starting ART before aged 12 weeks were HIV-seronegative by at aged ∼ 2 years. HIV-antibody tests cannot be used to re-confirm HIV-diagnosis in children starting early-ART. Long-term consequences of seronegativity need further study. Funding— Wellcome Trust, Medical Research Council, National Institutes of Health. This study presents the frequency of seronegative HIV status in HIV-infected children treated from <12 weeks of age, and the data is derived from a randomised controlled trial. HIV-antibody tests that are currently available should not be used to confirm HIV-status in HIV-infected children who initiated ART in the first 6 months of life. Future research should explore the clinical and immunological impact of HIV seronegativity.


LoRa, as a low-power wide area communication technology, has been applied in the field of substation. This paper briefly introduces the characteristics of LoRa technology, analyzes the current situation and existing problems of LoRa technology in communication rate, communication distance, network architecture and information security, demonstrates its application scenario combined with the characteristics of substation communication network, and finally prospects the application of LoRa technology in substations.


Abstract : This present monograph is an expansion of the Human Relations dimension of organizational leadership identified in Monograph 8 (AD-A090 479). It explores human relations in terms of interpersonal interaction and organizational development. Because this monograph is intended for service school instructors, it departs from the usual format and presents the subject first in terms of practical application, followed by the theoretical and historical basis for human relations development.


Senior Mechanical Engineer, Kodi Dixon, said the most difficult challenge was due to the difference between the WTP facilities being classified as general service with a 150 psig (10 bar-g) design pressure; and the Tank Farms facility being classified as safety significant with a 400 psig (28 bar-g) design pressure. In addition, the WTP facilities were under construction whereas the Tank Farms were in design.


The invention provides a preparation method of a VDMOS device. The method comprises that a potential dividing ring, a grid oxide layer and a polycrystal grid are successively prepared; a first P- body region is injected and driven, a second P- body region is injected and driven, and the driving junction depth of the second P- body region is lower than that of the first P- body region; and an N+ source region, a silicon nitride layer, a P+ deep body region, a dielectric layer, a contact hole and a source metal are successively prepared to form the VDMOS device. The preparation method of the VDMOS device solves the problems that in the prior art, adjustment of the threshold voltage of the VDMOS device causes grid-to-source electric leakage and influences the source-to-drain breakdown voltage and ON resistance.


In this paper, multi-channel estimation schemes for a GMSK-based system with transmit diversity (space-time coding) are presented. For such a system, the channel information (impulse response) is critical for both space-time decoding and equalization at the receiver. Three non-blind estimation schemes, which decompose the channel in the process, are proposed for the GMSK receiver to obtain the impulse response of each of the multipath channels (i.e. transmit antennas): oversampling deconvolution, minimum mean-square error, and joint adaptive and correlation estimation. Since the received signal is the sum of emitted GMSK signals, interference cancellation is employed to facilitate the estimation process. Three cancellation algorithms, including direct cancellation, mean-square cancellation, and iterative cancellation, combined with each channel estimation method are investigated and compared. The estimated channel information will feed to the receiver consisting of space-time decoder and equalizer to decode the symbols of interest. Two receiver architectures are investigated in this paper, where the first design is the space-time decoder followed by the equalizer, the other is in the reverse way (equalizer followed by space-time decoder). In each of the two receiver architectures, the channel estimation needs additional modification and so does the equalizer. The equalizer in the design is a maximum likelihood sequence estimation (MLSE) based on Viterbi algorithm. To prove the concept and algorithms, both simulation and hardware implementation are performed. From the experimental results, it is shown that all the channel estimation algorithms can produce acceptable impulse response for space-time decoding and equalizer, in which the joint adaptive estimation with iterative cancellation is superior to the others. It is also shown that the diversity gain of this transmit diversity system is as good as a system with the same degree of receive diversity.


The article deals with new approaches to the implementation of the main objectives of foreign language teaching in non-language universities. Competence approach to learning in higher education creates conditions for mastering professional competences complex. The socio-cultural, communication, information, social and psychological competencies can be formed in the process of learning a foreign language in high school. Use of credible sources in the process of learning a foreign language is able to significantly improve the efficiency of the educational activities of teachers and create an atmosphere of real language communication. A significant role in this task plays the encyclopaedic approach, which refers to the expansion of the range of the studied material.


Progesterone, 17\g=a\-hydroxyprogesterone,\g=D\4-androstenedione, 20\g=a\-hydroxypregn-4-en-3-one,testosterone, oestradiol-17s and oestrone were determined in twenty-one cyst fluids obtained from the ovaries of normally menstruating women and of patients with heavy irregular bleeding. In normally menstruating women, the proportion of oestradiol was higher than that of progesterone at the beginning of the cycle, whereas in patients with irregular bleeding, progesterone was the predominant steroid and, with oestradiol, was present at any time after


Posterior reversible cerebral edema syndrome is a generally reversible neurologic condition that is diagnosed based on distinctive clinical and radiologic findings. The condition, which is mostly associated with severe arterial hypertension, has also been reported to be induced by several medications. We made the diagnosis of hypertension with posterior reversible cerebral edema syndrome in a lean 12-year-old girl treated with the second-generation antipsychotic risperidone. We applied the Naranjo Adverse Drug Reaction Probability Scale and the World Health Organization–Uppsala Monitoring Centre system for causality assessment to the present case. Both scales indicated that a relationship to risperidone was likely. Second-generation antipsychotic agents may occasionally induce an increase in blood pressure even in the absence of overweight. Given this possibility, we recommend routine monitoring of blood pressure during therapy with these agents. Pediatrics 2014;133:e771–e774 AUTHORS: Gregorio Paolo Milani, MD,a Mario Giovanni Bianchetti, MD,b Marta Benedetta Maria Mazzoni, MD,a Fabio Triulzi, MD,c Massimo Carlo Mauri, MD,d Carlo Agostoni, MD,e and Emilio Filippo Fossali, MDa aPediatric Emergency Department, cNeuroradiology Department, and dClinical Psychiatry, Clinical Neuropsychopharmacology, Foundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy; bDivision of Pediatrics, Mendrisio and Bellinzona Hospitals and University of Berne, Berne, Switzerland; and eDepartment of Clinical Sciences and Community Health, University of Milan, IRCCS Ospedale Maggiore Policlinico, Pediatric Clinic 2, Milan, Italy


A number of economists have argued that the literature on the irreversibility effect implies that current abatement of greenhouse gas emissions should be greater when there is the possibility of obtaining better information in the future about the potential damages from global warming than when there is no possibility of obtaining better information. In this paper we show that even the simplest model of global warming does not satisfy either of Epstein's (1980) sufficient conditions, so it is not possible to use Epstein's analysis to tell whether the irreversibility effect applies to models of global warming. We derive an alternative sufficient condition for the irreversibility effect to hold.


The present invention relates to a vertically integrated system. Embodiment of the present invention provides an integrated circuit system, comprising: a substrate; a first semiconductor die on said substrate, said first semiconductor die comprises an active layer made of the front side and a back layer side member, wherein said member comprises a layer of discrete passive components; second semiconductor die on the substrate having the first semiconductor die different operating voltages; isolation barrier configured to the first and second semiconductor die electrically isolated from each other; and a communication circuit configured to transmit data between the first and the second semiconductor die.


Through the evaluation of Chen Yinke' s academic achievements and perspective, the analysis of his personality and cultural choice , the discussion of some problems in his study and thorough evaluation , we' ve got a conclusion that Chen lived in a sharp conflict of ration and emotion where he could on one hand be pully aware of the historical fate of old Chinese culture but on the other hand couldn' t get rid of it . His Poems Collection and all his other works had revealed this point. His idea base did not lie in humanism but in nationalism. What he pursues was not the truth to all over the world but the uncurable principles limited in a certain time and area. Chen is not a true liberal but a firm conservative.


Recently Multilevel inverter (MLI) have been attracting by researchers, they have been used in many fields such as high voltage direct current (HVDC) transmission lines, industrial and renewable energies. This paper presents a design of a new technique to generate optimum pulses using an optimal pulse generator (PG) controller exactly averaging technique for three different topologies of a 5-level multilevel inverter flying capacitor (FC), natural point clamped (NPC) and cascaded H-bridge (CHB). A comparison is made between these three inverters types in terms of output AC voltage wave forms and total harmonic distortion for AC output voltage (THDv%). Consequently, this paper presents comparative results with some previous researches to prove that the optimal pulse generator controller averaging technique is one of the best methods to reduce (THDv%). To achieve the results a MATLAB SIMULINK is used.


A method is proposed for estimating the horizontal movement of a long shallow buried pipeline due to the nearby excavation and backfilling of a long deep trench parallel to the pipeline. An elastic model of the problem consisting of a beam embedded in an elastic foundation which is locally displaced laterally is analysed. The effects of backfill stiffness and end restraint are examined. An approach is suggested for estimating the risk of pipe fracture. Une methode est proposee pout estimer le mouvement horizontal d'un oleoduc long, peu profond, dȗ a des excavations proches, et au remblayage d'une tranchee longue, profonde parallele a l'oleoduc. Un mode, e elasticlue du Probleme consistant en une poutre reposant sur une fondation elastique qui est localement deplacee iateralement, est analyse. Les effets de rigidite du remblai et des contraintes d'extremite sont examines. Une approche est suggeree pour estimer le risque d'une rupture de la conduite.


Objective To determine whether tissue factor(TF) is present in the amniotic fluid of normal term pregnancy. Methods Tissue factor antigen levels in amniotic fluid, blood plasma, centrifugal supernatant and sediment of 16 normal term pregnancies were detected with immunoenzymatic method(ELISA). Results Tissue factor antigen levels in the blood plasma, the whole amniotic fluid, the centrifugal supernatant and the sediment were [(31±9) ng/L0, [(404±186) ng/L], [(348±177) ng/L] and [(1360±639) ng/L], respectively. Tissue factor antigen concentrations in three states of the amniotic sediment(P0.001). Conclusions (1)High concentration of tissue factor antigen is present in the amniotic fluid of normal term pregnancy. (2) The concentration of tissue factor antigen of the cell-enriched amniotic sediment is the highest in the whole amniotic fluid. (3)Tissue factor in the amniotic fluid may be the trigger of disseminated intravascular coagulation(DIC) of amniotic fluid embolism.


VLSI designs contain very large resistive networks consisting of hundreds of millions (10e11) of resistors. Accurate parasitic extraction and analysis of such large networks is essential in many phases of the VLSI design flow. Existing techniques to analyze large resistive networks using linear solvers, despite recent optimizations, still take prohibitive computation time. In this paper a new technique based on low-distortion embedding to estimate point-to-point effective resistance is presented. Our proposed method employs recently discovered techniques from theoretical computer science to compute an ε-approximate resistance embedding matrix from which effective resistances of all node pairs can be estimated as easily as taking the Euclidean norm of column differences. The proposed method runs in almost linear time (linear in the number of resistors), and the accuracy (ε) is user specified. The method has been implemented and experimental results on large networks containing upto 10e11 nodes are presented. Compared to existing method using sparse linear solvers, our methods are more than 10 times faster on mesh networks and more importantly given a network of n nodes, allow computation of effective resistance between arbitrary node pairs in O(lg(n)) time (lg denotes logarithm to base 2).


Robot knowledge of the world is created from discrete and asynchronous events received from its perception components. Proper representation and maintenance of robot knowledge is crucial to enable the use of robot knowledge for planning, user-interaction, etc. This paper identifies some of the main issues related to the representation, maintenance and querying of robot knowledge built upon discrete asynchronous events such as event-history management and synchronization, and introduces a language for simplifying the developers' job at making a suitable representation of robot knowledge.


In this paper, we proposed a novel image steganographic method. Considering the visual quality of the stego-image, the pixels of host image are classified into three groups according to the noise visibility function values of the pixels. For each group of pixels, the corresponding secret pixel values go through an optimal substitution process and are transformed into other pixel values. Then the optimal substitution is obtained by dynamic programming strategy. To get the good image quality of the stego-image, the modulus function is employed to hide the secret bits into host pixels. According to our experimental results, this method can provide better stego-image quality than some traditional schemes.


OBJECTIVE
We evaluated the relationship between retired National Football League players executive functioning (EF) abilities on verbal memory performance and subprocesses.

METHOD
Fifty-eight participants were divided into two groups: intact executive functioning (IEF) and deficit executive functioning (DEF). Participants completed the California Verbal Learning Test, Second Edition (CVLT-II) to evaluate verbal memory performance. Additionally, the Item Specific Deficit Approach (ISDA) was applied to the CVLT-II to quantify verbal memory subprocesses (i.e., encoding, consolidation, & retrieval). Next, we determined which ISDA indices predicted long-delayed free recall (LDFR) for both groups. We then computed hierarchal regressions to determine which ISDA indices were predictive of LDFR for each group. Next, we retained significant predictors from the ISDA and correlated them with measures of executive function in both groups with and without partialling out cognitive reserve (CR).

RESULTS
We found the IEF group outperformed the DEF group on the CVLT-II learning trials and LDFR, and demonstrated better encoding abilities. Hierarchical regression revealed that the ISDA was predictive of LDFR in both groups. The DEF group LDFR issues were only predicted by encoding problems. In contrast, LDFR deficits in the IEF were primarily driven by consolidation problems. The ISDA encoding index correlated with Trail Making Test part B and Phonemic Fluency Test. However, after partialling out the variance accounted for by CR, the associations between the encoding index and executive function were nonsignificant.

CONCLUSIONS
Our results suggest that greater executive function results in better memory performances in retired football players. Lastly, improved executive function is related to greater CR.


The length of the South-to-North Water-Transfer Project general canal involving the expansive soil(rock) is approximately 386.8 km.The treatment of the expansive soil(rock) is the main technical problem to be tackled.In the project supported by the National Key Technology RD Program,various research means have been employed to investigate the failure mechanism of the expansive soil(rock) cannel slope comprehensively.The slope stability analysis method for the expansive soil cannel slopes has been proposed,the economic and applicable treatment measures have been put forward.In this paper,the research content,technical route are introduced and the results of the project systemically illustrated.The research results could also provide reference for the relevant research and engineering projects.


This chapter offers a critique of the ways in which we approach the study of civil society, and digital technologies through the notion of public sphere theory. In it, I question whether public sphere theory is up to the job of dealing with a democratic deficit so large that it challenges the notion that liberal democracy should always be our 'go to' democratic frame. Classical public sphere theory begins and ends with liberal democracy as its overarching premise and ultimate political institutional arrangement. But what if we start from a different position where we acknowledge that liberal democracy has been so dismantled that it is now eviscerated and unrecognizable to many in civil society? Can a concept so undone really offer a critical perspective suggestive of democratic futures or is it rather holding us back, capturing us in the comfort zones of liberalism that threaten ultimately to erode democracy yet further?


Visible light communication (VLC) and non-orthogonal multiple access (NOMA) have been deemed two promising techniques in the next wireless communication networks. In this paper, secure communications in the presence of potential eavesdropper are investigated for a multiple-input single-output VLC system with NOMA. The artificial noise jamming and beamforming technologies are applied to improve secure performance. A robust resource allocation scheme is proposed to minimize the total transmit power taking into account the constraints on the quality of service requirement of the desired users and the maximum tolerable data rate of the eavesdropper, and the practical imperfect channel state information of both the desired users and the eavesdropper. The formulated non-convex optimization problem is tackled based on S-Procedure and semi-definite programming relaxation. Simulation results illustrate that our proposed resource allocation scheme can effectively guarantee communication security and achieve transmit power saving. Moreover, the height and number of LED can significantly affect system performance and the optimum LED height can be obtained for different LED numbers.


Q235 steel was chromized by using glow plasma surface alloying technique under different powers, gas pressures and temperatures of the process parameters. Use metallographic microscope and scanning electron microscopy to observe morphology of the layer. Use EDS to determinate the concentration of Cr distribution in the layer, and use X diffractometer to get the phase analysis. The results show that all the layers of chromizing appear reaction-diffusion phenomena under different powers, there are clear columnar structure in the layers; the maximum thickness of the layer reached to 100 μm and more than; the surface chromium content is about 40 % (w %), 10 μm from the surface layer department chromium content above is 10 %. The composite distribution of pulse power supply of the alloying layers was obviously better than DC power supply and double power supply alloying layers. With pressure increasing under pulse power supply, Cr layer thickness and the content first increased and then decreased. The optimum gas pressure parameter is 30 Pa under the process conditions. Under pulse power supply, thickness of Cr layer increases with the working temperature increasing. And from the surface to internal the Cr concentration gradient flattens out and improves with the working temperature increasing.


Objectives: To observe the effect of Biyufen combined with ulcer paste on the repair of radiation-induced skin injury after breast cancer surgery.Methods: Twenty-eight cases of Grade II radiation-induced skin injury were treated with Biyufen and ulcer paste.Ulcer paste was applied to injury area,and Biyoufen was applied to the non-injured area or the repair area.The treatment continued till 2-4 weeks after the complete repair in order to protect the repaired skin against reinjuring and to restore the skin elasticity and light pigmentation.Results: After 3 to 9 days of treatment,28 patients showed complete repair of their injured skin.Skin elasticity was restored and dark skin pigmentation reduced or disappeared after 1-2 weeks.Conclusion: The combined treatment of Biyufen and ulcer paste has ideal effects on the repair of radiation-induced skin injury after breast cancer surgery.


While devolution has provided a stronger political voice for Scotland, Wales and Northern Ireland since the late 1990s, it is only in the past few years that English public opinion appears to have become exercised by the lack of similar arrangements for England. The renewed debates over the character of the Union after the Scottish independence referendum reveal a desire for 'fair treatment' of England within a Union conceived as a partnership of equals. At the same time, numerous proposals have been made for devolution of power within England, reflecting long-held concerns about the territorial hegemony of London. Solutions to the former issue include English votes for English laws and an English Parliament. Solutions to the latter include city-regions, strengthened local government, the first of these appears to be the government's preferred route, in the light of the recent 'Greater Manchester Agreement'. However, none of these 'solutions' can count on being implemented.


564 Agranulocytosis W. DAMESHEK and M. INGALL (Amer. Journ. Med. Sci., April, 1931, p. 502) report 9 cases of agranulocytosis (termed malignant neutropenia), of which 4 were typical of the angina agranulocytica of Schultz. Two were infantile cases, which is rare; two patients recovered. In one case arsphenamine injections were a probable etiological factor. Six patients were in the fourth decade of life. Though the disease is said to be more frequent in


This paper reports on the development of a low-cost microreactor (10 µl) biochip for DNA polymerase chain reaction (PCR). The microbiochip (20 mm × 28 mm) is a hybrid type that is composed of a polydimethylsiloxane (PDMS) layer with a serpentine microchannel (360 µm × 100 µm) chamber and glass substrate integrated with a microheater and thermal microsensor. Because of the hydrophobic chip surface, bubbles are usually created during sample loading in the PMDS-based microchip. These bubbles disrupt the stable biochemical reaction. An improved microreactor chamber was designed using microfluidic simulation. The reactor has a rounded-corner serpentine channel architecture, which enables stable injection into the hydrophobic surface using only a micropipette. The reactor temperature needed for the PCR reaction is controlled within ±0.5 °C by the LabVIEW software proportional-integrative-derivative (PID) controller. PCR analyses of the sex-determining Y chromosome (SRY) gene and mouse GAPDH gene were successfully performed in less than 54 min by the fabricated microreactor chip.