A microfabricated hollow air-filled waveguide with two back-to-back bends operating in the WR-3 frequency range of 220 to 325 GHz has been successfully fabricated through a multilayered ultrathick SU8 process and has ultralow transmission loss of 0.028 to 0.03 dB∕mm in a performance test. This is the first SU8 constructed hollow waveguide operating at WR-3 frequencies having transmission loss comparable with the state-of-the-art computer numerical control (CNC) machined metal circuits. The multilayered SU8 processing technique has a great advantage of reducing the transmission loss by decreasing the probability of air gaps between SU8 layers. The excellent device performance is also attributed to the precisely controlled layer thickness and ultimately low surface roughness of evaporated silver which only contributes a small part of the microwave signal attenuation. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1 .JMM.13.1.013002]


On December 2, 1942, the nuclear age was initiated with the first controlled release of nuclear energy. This issue of the Bulletin of the Atomic Scientists is devoted to the events of the past twenty years and their implications for the future.


A digital elevation model(DEM)is used to define the target area,and the target basin is subdivided into a number of fundamental units for hydrological simulation.The catchment parameters related to topography,land use and soil are then calculated for each simulation unit.Geographical information defines the general structure of the distributed hydrological model.The study basin is divided into a discrete grid system,which is represented by a number of geometrically symmetrical hillslopes.The river network is divided into subcatchments of an appropriate size.The hydrological simulation part includes runoff generation from the hillslope and the flow routing in the river network.The GBHM(geomorphology based hydrological model)employs a flow-interval hillslope discretization scheme in the representation of hydrological processes using catchment geomorphologic properties.Furthermore,the paper also combined the water quality model of coupling with the survey values.The results show that the distributed hydrological model and integrated simulation is suitable for hydrology and quality change in the Weihe river basin.


Dynamic and real-time monitoring of substation, the analysis of the operating state of the substation through the phasor values of the substation. The phase of accurate measurement is a prerequisite to ensure accurate analysis Substation running state. This paper uses Fourier algorithm, recursive least squares algorithm and Kalman algorithm three methods of phasor calculation solving the acquisition voltage, current from the substation, get the results of calculation and error analysis. Come up with a more accurate method of phasor calculation. Provide a practical method for the accurate analysis of the operating state of the substation.


Context: Quassinoids are biologically active secondary metabolites found exclusively in the Simaroubaceae family of plants. These compounds generally present important biological properties, including cytotoxic and antitumor properties. Objective: In the present study, the cytotoxic effects of neosergeolide, a quassinoid isolated from Picrolemma sprucei Hook. f., were evaluated in human promyelocytic leukemia cells (HL-60). Materials and methods: Cytotoxicity and antiproliferative effects were evaluated by the MTT assay, May-Grünwald-Giemsa's staining, BrdU incorporation test, and flow cytometry procedures. The comet assay and micronuclei analysis were applied to determine the genotoxic and mutagenic potential of neosergeolide. Results: After 24 h exposure, neosergeolide strongly inhibited cancer cell proliferation (IC50 0.1 µM), and its activity seemed to be selective to tumor cells because it had no antiproliferative effect on human peripheral blood mononuclear cells (PBMC) at tested concentrations. Apoptosis was induced at submicromolar concentrations (0.05, 0.1, and 0.2 µM) as evidenced by morphological changes, mitochondrial depolarization, phosphatidylserine externalization, caspases activation, and internucleosomal DNA fragmentation. Additionally, neosergeolide effects were prevented by cyclosporine A (CsA), an inhibitor of the mitochondrial permeability transition (MPT) pore, which reinforced the participation of intrinsic pathways in the apoptotic process induced by this natural quassinoid. Direct DNA damage was further confirmed by comet assay and cytokinesis-block micronucleus test. Discussion and conclusion: The present study provided experimental evidence to support the underlying mechanism of action involved in the neosergeolide-mediated apoptosis. In addition, no antiproliferative effect or DNA damage effect of neosergeolide was evident in PBMC, highlighting its therapeutic potential.


Abstract: The following examines the Akkadian scribal annotation tayyartu, "return," demonstrating that it refers to a repetitive section of a text that was not copied by the scribe. Editions of two texts where this annotation occurs, a Mīs Pî-type incantation and an Emesal prayer, are included. In addition, the phenomenon of repetition and abbreviation in incantations and Emesal prayers is briefly discussed.


In this study, the effects of the leaves of V. doniana aqueous and ethanolic extracts on postprandial blood glucose was analyzed. In the first experiment, 25 Wistar albino rats were divided into 5 groups of 5 rats each. Treatment was carried out orally for one day. Overnight fasted animals (group 2-4, 18 hrs) were orally administered different doses of the extract 10 minutes prior to the administration of sucrose at a dose of 2 g/kg. The postprandial blood sugar was measured before administration (at 0 minute), and after administration (30, and 60 minutes). In the second Original Research Article


This interactive session focuses on the use of psycho-physiological methods in information science research. Through presentations, demos, and interactive discussion we will discuss and observe pragmatic issues of implementing these methods in IS and analyzing the data they generate. We will also examine the "fit" of these methods of measuring IS concepts and phenomenon, their reliability and validity, and the need for greater knowledge exchange amongst IS researchers to guide the effective use of these methods.


Whatever role you have, this space should address topics of interest to you, as well as provide insights for how we can work better together. I will ensure that the scope of this space includes issues and developments that arise at any part of the KM life cycle---from prototype development through the implementation and maintenance phases. Let us know who you are, and make sure that your areas of interest get heard.


Objectives:
Research on celebrity attitudes have mainly focused on women. This study examines whether there are gender differences in levels of celebrity attitudes. Additionally, it examines if there is a gender difference in the effect celebrity attitudes have on life satisfaction.

Method:
A convenience sample of (n=129) participants was included. There was a gender ratio of females (n=78) and males (n=50). Two questionnaires were administered through online platforms, comprising of the Celebrity Attitudes Scale (CAS) and the Satisfied With Life Scale (SWLS). Consent and demographic information were also obtained.

Results:
There was no significant differences found between men and women's scores on the CAS. There were no significant correlations found between CAS scores and SWLS scores.

Conclusion:
As there was no significant gender difference found in celebrity attitudes, the results of this study expand and develop previous research on gender differences in celebrity attitudes. It acts as a foundation study, to include males in future studies on the impact of celebrity attitudes. Additionally, this study produced unexpected results, finding no significant correlation between high levels of celebrity attitudes and life satisfaction. This is in contrast from previous empirically supported studies. Therefore, further research is needed to examine why these results occurred.


An effective method of developing coordination abilities can be a gymnastic stick use in physical education at school. The development of spatial orientation was in children aged 8-9 years. 104 students took part in a study in the city of Kirov (Russian Federation). At school 60, children do physical education 2 times a week for 40 minutes. They were divided into 2 groups. The experimental group consists of schoolchildren who studied according to the usual methodology and additionally performed physical exercises on the gymnastic stick. Children from the control group were engaged in a standard program for schoolchildren of grades 1-11. The ability to kinesthetically differentiate the parameters of movements was determined using the "Hitting the ball on target" test. The Student's T-test was used to process the results. After the end of the pedagogical experiment, the indicators of children in the control group improved by 26% (p>0.05), the positive dynamics can be explained by a natural increase in coordination abilities at the age of 8-9 years and the effectiveness of using the standard physical education program in Russian schools. The indicators of children in the experimental group improved by 73% (p<0.05). Such results can be explained by the effectiveness of the implementation of a set of exercises using a gymnastic stick in physical education lessons. The indicators of kinesthetic differentiation of movement parameters will significantly improve if children aged 8-9 perform a set of physical exercises on the gymnastic stick during physical education lessons.


IntroductionHeadache is a common symptom among patients on hemodialysis, occurring in up to 70%. Dialysis headache is defined by the International Classification of Headache Disorders (ICHD-3) as a headache with no specific characteristics, occurring during and caused by hemodialysis, and which resolves spontaneously within 72 hours after the session has ended. There is no consensus on its pathophysiology or triggering factors.
ObjectiveTo evaluate the prevalence, clinical features and factors associated with dialysis headache in patients with chronic kidney disease on renal replacement therapy.
MethodsCross-sectional observational study with a quantitative approach. Participants were divided into two groups: (1) 25 patients on hemodialysis and (2) 25 patients on early post kidney transplantation. All participants were interviewed with a structured questionnaire, the Hospital Anxiety and Depression Scale, and the Epworth Sleepiness Scale. Blood pressure, weight, urea, glucose and electrolytes were evaluated before and after one hemodialysis session. Control groups were classified within the headache-free patients in each group. Numerical variables were expressed as mean and standard deviation and evaluated using Student's t test (two-tailed) or Mann-Whitney U test. Categorical variables were expressed as percentage and evaluated using Pearson's chi- squared test. The p value was considered statistically significant when lower than 0.05.
ResultsIn group (1), 8 patients (32%) were diagnosed with dialysis headache, predominantly pulsatile (n=6, 75%), accompanied by photophobia (n=6, 75%), phonophobia (n=4, 50%) and nausea or vomiting (n=6, 75%), with a mean pain score of 7.75 ± 1.58. Individuals with headache had higher scores for anxiety (7.00 ± 3.93 vs. 3.82 ± 3.23, p=0.03) and sleepiness (9.13 ± 3.94 vs. 4.76 ± 3, 85, p=0.01). (To see the complete abstract, please, check out the pdf).


Age-related macular degeneration(AMD) belongs to the category of refractory eye disease,and it is one of the leading causes of blindness in the elderly.Inflammatory theory is one of the pathogenesis of the disease,while the complement system,C-reactive protein,and interleukin,etc.might as important factors involve in the formation of AMD.Tumor necrosis factor might be an important factor in the production of choroid angiogenesis membrane.From the perspect of searching for root course of disease and simultaneous treatment of the symptoms and root cause,traditional Chinese medicine had certain curative effect.This paper is an overview of TCM treatment of AMD.


Medical and Surgical Approaches to Dystonia The Treatment of Dystonia with Botulinum Toxins The Role of the Nurse Practitioner and Physician Assistant in the Management of Dystonia Dystonia from a Social Work Perspective Speech and Swallowing Orders in Dystonia The Role of Physical Therapy in the Management of Dystonia The Role of the Occupational Therapist on the Interdisciplinary Team Evaluation and Treatment of Dystonia: The Role of the Psychologist in Dystonia Psychiatric Considerations in the Dystonia Patient Programming Deep Brain Stimulators in Dystonia


This study proposes a simple method for creating flat beam patterns in a near-field. In radio-wave transmission, the near-field beam efficiency of the beam-type wireless power transfer (WPT) system theoretically reaches 100%, but the beam pattern is not flat in the near field. In real beam-type WPT systems, the total beam efficiency (DC-RF-transmission, beam efficiency, and RF-DC conversion) can be improved by increasing the RF-DC efficiency of the rectenna. However, the rectenna requires a flat beam pattern in the near-field. In the present study, we create a flat beam pattern in the near field of a multicopter assisted wireless batteryless sensing system.


Because my article was not a review of Richard J. Evans's book, but a thought piece on broader topics prompted by his work, it does not stick only to issues discussed by him. What a shame that Cosmopolitan Islanders was largely ignored, as Evans reports, for he raises important questions. Part of the reason for the book's stillbirth is exemplified in Evans' response here: the self-isolation of the historical profession that is met by increasing indifference from the rest of the thinking world. Evans's concern to draw fine distinctions and quarantine history apart from all other social science is telling. Yes, Myrdal was a sociologist (well actually an economist, but no matter). And, yes, some of the foreign scholars I mention who write about the Anglosphere work on literature, not history as such. Why such vigorous policing of the disciplinary boundaries when larger issues are at stake? No wonder historians now have their largest audiences among the military history buffs while the more adventurous social sciences cash in on our work in ways we spurn. What William McNeill used to do has become the province of Francis Fukuyama.


OBJECTIVES
To determine whether the direct application of a single dose of methadone on the dura mater at the end of surgery to repair a lumbar disk hernia provides effective analgesia over the next 24 hours.

PATIENTS AND METHODS
We conducted a randomized double blind study in 40 ASA I patients undergoing elective herniated disk repair under general anesthesia. The sample was divided into two groups (A and B). Group A patients received a solution of methadone in saline solution (5 mg methadone/5 ml saline) applied to the dura before the end of surgery. Group B patients (controls) received only 5 ml of saline. Pain intensity was assessed on a visual analog scale (VAS) during the postoperative period. Also recorded were the observer's impression and the amount of analgesia (ketorolac) consumed through a system providing patient controlled analgesia.

RESULTS
Each group contained 20 patients. Group A patients needed significantly less postoperative analgesia (64.2 +/- 14.3 mg) than group B patients (109.6 +/- 16.5 mg). The VAS scores were significantly lower in group A during the first two hours after surgery and were correlated with the observer's impression. No patients suffered serious complications during the study.

CONCLUSIONS
Topical administration of 5 mg of methadone on the dura mater at the end of herniated lumbar disk repair is an easy, safe and effective technique for providing postoperative analgesia.


Recently, Gates described several simulation experiments in an attempt to demonstrate the superiority of Gates. model over Friedman.s model to determine the probability of winning a construction contract letting. This note explains why Gates. paper misrepresents Friedman.s model; does not display a sound comprehension of the basic tenets f probability; misinterprets the results from an unnecessary simulation; and wrongly pronounces the validity of Gates. model. The reader is assumed to have read Gates. paper, as references to equations and tables in it shall be made.


The advent of IEC 61850 provided generic hardware platforms with a standard communication interface and left remaining problem is the unified function model that can specifies various software components and provides a framework to integrate them efficiently. The standard function blocks method can provides the unified function model. In this paper we report on the architecture specifies a design template for the executable reservation interlocking scenario. The design makes the reservation interlocking modules executable and integration repeatable, provides for the seamless distribution application and the reuse of the configuration when the same instance occurs. The system of reservation interlocking is simulated in an IEC 61499 execution environment FBDK conducted to prove the feasibility and flexibility of using function blocks method.


Summary Alkylation of whole casein samples by reaction with cysteamine and cystamine in a bis-tris-propane–urea buffer (pH 7·0) followed by fast protein liquid chromatography (FPLC) at 20°C on a Mono Q HR5/5 column in the same buffer and using a NaCl gradient led to good resolution of the whole casein into fractions representing (i) γ2- plus γ3-caseins, (ii) κ-caseins, (iii) β-casein, (iv) αs2-caseins and (v) αsl-caseins, together with small amounts of unidentified materials. Quantitatively the FPLC values agreed well with those for αs1-, β-, αs2- and γ2- plus γ3-caseins obtained by ion-exchange chromatography on DEAE cellulose, Whatman DE52 and with those for º-caseins obtained by gel-permeation chromatography on Sephadex G–150.


In mechanical manufacturing, the factors such as power energy loss,fiction of moving parts,material cutting and the external environment will make machine tools heated and deformed.The thermal deformation of machine tools will seriously affect the processing precision and the error of processed parts.Constructing mathematical models of thermo-deformed machine tool parts will benefit the analysis and elimination of the effect of thermal deformation on processed parts.


Nominal encapsulators, also referred to by other terms coined in the Spanish tradition (discursive labels), are textual cohesion devices, frequently used in journalistic discourse to condense and summarize the predicative contents of a sentence or a textual sequence. These nominal units (nouns or syntagms) can synthesize texts of different length or even refer to discontinuous fragments. Apart from performing this very basic function founded on the discursive economy of the journalistic genre, the nominal encapsulators allow the author to recategorize the content of the encapsulated segment through different evaluative modifiers and therefore to obtain either a negative or a positive perception of the message by the reader. Given an apparent lack of research on the subject on encapsulation devoted tomore than one language, our purpose is to carry out a contrastive analysis of the said phenomenon in Spanish and Polish in order to juxtapose the values and the frequency of usage of encapsulators with certain characteristics of both languages. Some formal as well as pragmatic and semantic features of nominal devices are thus analysed, namely their encapsulating mechanism, their degree of modification and some of their discursive functions.


In non-commutative spaces the invariant eigen-operator(IEO)method is used to calculate the energy spectrum of two dimension quantum harmonic oscillators with saddle potential.Four different coupling ways in harmonic oscillators with saddle potential have been considered:no coupling,coordinate coupling,momentum coupling and coordinate-momentum coupling.The result shows that IEO method can solve these problems well and gives the relation between energy level gap and coupling coefficient.


The perceived competence of nursing students in performing resuscitation after completing an ACLS certification course was explored. This evaluation will aid in program evaluation and serve as a basis for further investigation. Baccalaureate nursing students receiving ACLS certification in the final semester of their nursing education self-reported an increase in perceived confidence related to performing resuscitation following the ACLS course.


We examine the capabilities of the DUNE experiment as a probe of the neutrino mixing paradigm. Taking the current status of neutrino oscillations and the design specifications of DUNE, we determine the experiment's potential to probe the structure of neutrino mixing and CP violation. We focus on the poorly determined parameters $\theta_{23}$ and $\delta_{CP}$ and consider both two and seven years of run. We take various benchmarks as our true values, such as the current preferred values of $\theta_{23}$ and $\delta_{CP}$, as well as several theory-motivated choices. We determine quantitatively DUNE's potential to perform a precision measurement of $\theta_{23}$, as well as to test the CP violation hypothesis in a model-independent way. We find that, after running for seven years, DUNE will make a substantial step in the precise determination of these parameters, bringing to quantitative test the predictions of various theories of neutrino mixing.


Communication from the Commission amending the Community guidelines on State aid to promote risk capital investments in small and medium-sized enterprises, OJEU C 329, 7 December 2010, p. 4 Un…


The utility model relates to an RFID Internet-of-things parking lot management system which comprises the following components: a centralized control terminal, a parking lot gateway charging management subsystem, a parking lot space guiding subsystem, a parking lot reverse-direction vehicle-searching subsystem and a mobile phone application terminal. The centralized control terminal is connected with the parking slot gateway charging management subsystem, the parking lot space guiding system, the parking lot reverse-direction vehicle-searching subsystem and the mobile phone application terminal respectively. Compared with the prior art, the RFID Internet-of-things parking lot management system is advantageous in that: the RFID and the mobile phone are combined as a parking slot inlet/outlet warrant of the user; full-course service from reserving, guiding and reverse searching are provided for the vehicle owners; simultaneously the system automatically calculates parking cost of the vehicle owner; the parking cost can be paid in one time through a mobile phone mode or RFID mode; etc.


Aim: The aim of the study is to explore the influence of stress in patients with temporomandibular disorders Objectives: Stress affects the physiological, cognitive, emotional, behavioural functioning of human being. Initially our body compensates for stress, but when we cannot cope up with it, disorder arises. One such manifestation of stress in human body is temporomandibular disorders. The objective of the study is to first establish the diagnosis of the patients' complaints pertaining to temporomandibular joint based on clinical and radiological examinations; then to assess the degree of stress using stress assessment questionnaire and finally to study the relationship between stress and adaptability in temporomandibular disorders. Materials and Methods: 60 patients who reported with pain, tenderness in the temporomandibular joint, clicking or crepitus, tenderness in muscles of mastication, restricted mouth opening, deviation of jaw, restricted jaw movements, and with altered condylar movements were selected for the study. Clinical examination of signs and symptoms were assessed along with a stress assessment questionnaire. Finally, statistical analysis was performed on the responses received from the patients. Results: Significant difference was found in the pain threshold i.e. pain perception between patients with stress and without stress. This leads to the conclusion that stress has a major role in affecting the adaptability of the body, and it is a front runner for various deleterious effects. Conclusion: Stress levels of patients with temporomandibular disorders should be always evaluated and in case the stress levels are high, it must be treated with appropriate stress management therapy.


Cyclic dimeric GMP (c-di-GMP) is a global second messenger which controls a range of different cellular functions in bacteria at transcriptional, translational, and post-translational level. c-di-GMP binds to various receptor proteins or riboswitches and regulates biofilm formation, motility, cell cycle progression and virulence in bacteria (2). The intracellular level of c-di-GMP is controlled by the opposing action of two different groups of enzymes. The diguanylate cyclases containing the GGDEF domain produce c-di-GMP from two molecules of GTP, whereas specific phosphodiesterases (PDEs) associated with EAL or HD-GYP domains hydrolyze the cyclic molecule c-di-GMP to linear 5-pGpG, which is subsequently hydrolyzed into two GMP molecules (1,2) . The increase in intracellular c-di-GMP concentration leads to biofilm formation while its decrease enhances bacterial mobility and virulence. Here, we discuss the biochemical and structural aspects of EAL domain protein from Vibrio cholerae O395 (VcEAL). In Vibrio cholerae, EAL domain plays a crucial role in biofilm dispersal by reducing the c-di-GMP concentration in the cell, thereby inhibiting cholera pathogenesis and disease transmission by making it susceptible to antibiotic treatment. VcEAL was overexpressed and purified and high resolution crystal structures of EAL domain in complex with its substrate c-di-GMP and metal ions involved in catalysis or in enzyme inhibition at different pHs (1.95 Å, 2.3 Å) or in apo form (2.4Å) were determined. Apo and holo VcEAL structures looks very much similar indicating there is subtle change upon c-di-GMP binding. Comparing c-di-GMP/EAL interactions coupled with multiple sequence alignment revealed 12 conserved residues in the active site which modulate c-di-GMP binding/release. Of these 12 residues, 7 residues (mostly Glu or Asp) interact directly with c-di-GMP through two metal ions. Two oxygen atoms of the c-di-GMP and potential catalytic water molecules in the active site complete the coordination. Through kinetic studies we demonstrate that VcEAL is a potent phosphodiesterase. The phosphodiesterase activity is optimal at alkaline pH and strongly dependent upon Mg2+ or Mn2+ whereas Ca2+ inhibits the reaction. We have generated a set of mutants and assessed their enzymatic activity the results of which will also be presented.


Every single word or sentence we utter every day should carry particular meaning that our listener can digest well. When we speak or write something with words contained in it, the meaning is considered as being contributed to it. This research aims to study some words which are identified similar by pronunciation and spelling, but the meaning may be either different or similar. This research was undertaken by the researcher used type of descriptive qualitative method seen from the objective of research and qualitative research seen from the inquiry mode used. The results of the research are the researcher found that there are ten homonym words and five polysemy words found in novels Waiting on You and the Dancer.


Quinoline and four monofluorinated derivatives of quinoline (FQ's) were tested for their clastogenicity in a Chinese hamster lung (CHL) cell line using chromosomal aberration (CA) and micronucleus (MN) tests. Quinoline and all the fluoroquinolines, 3-, 5-, 6-, and 8-FQ, induced CA in the presence of the metabolic activation system. However, the clastogenic property was altered by fluorine-substitution. 3-FQ showed reduced cytotoxicity and clastogenicity. It was positive only at a higher dose than the other compounds. 6-FQ was as cytotoxic and clastogenic as quinoline when tested in the lower dose range (less than 0.075 mg/ml). 5-FQ and 8-FQ were only moderately clastogenic in the CA test although their toxicity was similar to that of quinoline. The MN test showed almost the same tendency in clastogenicity as the CA test, except that 8-FQ showed a negative result. These results demonstrate that fluorine-substitution can modify the clastogenicity of quinoline, probably through interference of the metabolic activation.


The invention relates to a low voltage promoting device which comprises a voltage division circuit, a reference voltage circuit, a switching circuit and a promoting unit, wherein the voltage division circuit is used for dividing the voltage of a rechargeable battery so as to generate detection voltage; the reference voltage circuit is used for receiving the voltage of the rechargeable battery so as to generate a constant reference voltage; the switching circuit is respectively connected with the voltage division circuit and the reference voltage circuit and used for switching on when the detection voltage is lower than the reference voltage; and the promoting unit is used for receiving the reference voltage provided by the reference voltage circuit for powering up and working when the switching circuit is switched on so as to send out prompt information.


The ribonucleases (RNases) present in a number of human tissues, including heart, brain, lung, and kidney, were purified, partially characterized, and compared in their properties to the previously described RNases from human liver, spleen, pancreas, and serum. The enzymes appeared to fall into two major classes: liver-spleen type RNase and plasma-type RNase. These two types of enzymes were present in varying proportions in all tissues examined. The extent to which the tissues studied possibly contribute to serum RNase levels is discussed.


Inappropriate speed is a factor in many fatal and serious accidents on roads in the Scottish Borders. Advice to drivers on speed and its enforcement on Border's roads.


The aim of this paper is to assess the impact that pollutant sources and ventilation strategies have on thermal comfort levels and indoor air quality (IAQ) in low energy houses through a case study using the detailed thermal simulation program, ESP-r. CO2 is commonly used as a proxy for IAQ, but a novelty of this research is the integrated analysis of distribution for other pollutants, specifically formaldehyde. A model was created based on monitored data from a low energy house. Acceptance criteria for calibrating the model were defined, addressing the current absence of specific guidelines for model calibration based on the monitored indoor environment. Then, a review of current literature of indoor pollutants was undertaken and three time-dependent models were implemented in ESP-r to model formaldehyde emissions. Different scenarios were defined to investigate specific design questions and common ventilation issues regarding the indoor environmental quality (IEQ). The results demonstrate that detailed modelling and simulation can predict IEQ issues and help to design ventilation strategies in low energy houses.


Through the biotechnology of the force-feeding chair and the hunger strike in Guantanamo, this paper examines the camp as a site of necropolitics where bodies inhabit the space of the Muselmann – a figure Agamben invokes in Auschwitz to capture the predicament of the living dead. Sites of incarceration produce an aesthetic of torture and the force-feeding chair embodies the disciplining of the body and the extraction of pain while imposing the biopolitics of the American empire on "terrorist bodies". Not worthy of human rights or death, the force-fed body inhabits a realm of indistinction between animal and human. The camp as an interstitial space which is beyond closure as well as full disclosure produces an aesthetic of torture on the racialised Other through the force-feeding chair positioned between visibility and non-visibility. Through the discourse of medical ethics and the legal struggle for rights, the force-feeding chair emerges as a symbol of necropolitics where the hunger strike becomes a mechanism to impede death while possessing and violating the corporeal body.


Composite likelihood methods have become popular in spatial statistics. This is mainly due to the fact that large matrices need to be inverted in full maximum likelihood and this becomes computationally expensive when you have a large number of regions under consideration. We introduce restricted pairwise composite likelihood (RECL) methods for estimation of mean and covariance parameters in a Gaussian random field, without resorting back to the full likelihood. A simulation study is carried out to investigate how this method works in settings of increasing domain as well as in-fill asymptotics, whilst varying the strength of correlation. Preliminary results showed that pairwise composite likelihoods tend to underestimate the variance parameters, especially when there is high correlation, while RECL corrects for the underestimation. Therefore, RECL is recommended if interest is in both the mean and the variance parameters.


Although early research has pointed to the fact that the successful intervention and resolution of cyberbullying incidents is to a large degree dependent on such incidents being reported to an adult caregiver, the literature consistently shows that adolescents who have been bullied tend not to inform others of their experiences. However, the reasons underlying reluctance to seek adult intervention remain undetermined. Understanding the factors that influence adolescent resistance will assist caregivers, teachers and those involved in the formulation of school anti-bullying policies in their attempts to counter the cyberbullying phenomenonre should be a space before of 12-point and after of 30-point.


in the treatment of chronic obstructive pulmonary disease (COPD), this book provides comprehensive discussions on the multifaceted aspects of treating this disease (as you hum the song by Sting). Written by many of the key opinion leaders in the field, the chapters cover physiological, laboratory, outcomes assessment and specific therapies for COPD. Each chapter is also well referenced, so one can look up the original sources. Even for those familiar with COPD, many of the authors discuss cutting edge issues in the field, e.g. that inspiratory capacity (IC) values, a measurement of lung volume, may be more sensitive than expiratory airflow measurements like FEV1 on clinical outcomes such as exercise performance and dyspnea; that sleep quality is frequently ignored in research protocols assessing quality of life; and that candidate genes may affect risk for developing COPD as well as response to therapy. Bart Celli, the editor of the volume, then ends the book with a chapter on how to treat COPD and the paradigm shift needed: COPD today is similar to hypertension in the past. Both use surrogate markers to measure outcome, and the available pharmacological treatments only cause modest effects on outcomes. Yet more research is needed in COPD to understand how various measurements, e.g. FEV1, FEV1/FVC ratio, inspiratory capacity, questionnaires, etc. evaluate outcomes important to patients such as exercise, sleep, dyspnea, morbidity and mortality. He also provides some useful flowcharts on how to treat patients with different degrees of COPD severity by their symptomatology. My only suggestion is that the book could have been improved if there had been an introductory chapter defining COPD: its heterogenous nature, different symptomatology, degrees of severity, factors in causation and so on. COPD is defined as a disease with irreversible airflow obstruction, measured by expiratory airflow levels with cut-offs that vary according to different thoracic organisations. Patients with COPD may have symptoms of chronic bronchitis, emphysema and/or asthma. However, most people with mild to moderate disease are not diagnosed, and the discussions by the authors address only the tip of the iceberg. Overall, however, this book will prove to be a handy reference for researchers and clinicians interested in COPD. Linda C. Koo, Chadds Ford, PA, USA


This thesis deals with seniors from the perspective of the target group for commercial ad-vertising. Explores the importance of this group for marketing communications, segmenta-tion tools, media consumption, advertising and advertising communication trends.


Concerns raised during the Ulysses Final Safety Analysis Review (FSAR) process called the solid rocket motor (SRM) fragment velocity prediction model into question. The specific area of concern was that there was a section of the SRM casing which was exposed to SRM chamber pressure as the grain (fuel) was consumed. These questions centered on the velocity of fragments which originated from the field joint region given that failure occurred between 37 and 72 seconds mission elapsed time (MET). Two dimensional coupled Eulerian‐Lagrangian calculations were performed to assess the hot gas flow field which resulted from SRM casing fragmentation. The fragment to gas interface‐pressure time‐history obtained from these analyses was reduced to a boundary condition algorithm which was applied to an explicit‐time‐integration, finite element, three dimensional shell model of the SRM casing and unburned fuel. The results of these calculations showed that the velocity of fragments originating in the field joint was ade...


A continuum model for evaluating partially composite insulated concrete sandwich panel deflections with discrete shear connectors due to differential volume changes such as those caused by differences in temperature between the wythes is evaluated for accuracy by comparison with finite-element analysis. Design equations for computing these deflections are provided. Analysis of sample panels indicates that the continuum model provides acceptable accuracy for calculating thermal bowing of wall panels. The resulting equations show that, for long panels, the amount of thermal bowing in the panels is relatively insensitive to the stiffness of the connectors. This implies that long insulated sandwich panels with low connecting-layer stiffness will experience nearly the same amount of thermal bowing as fully composite panels.


Introduction 1. The Hermeneutic Matrix 2. The Lutheran "Metaphysical" Tradition in Music and Music Theory 3. Cantata 21, "Ich hatte viel Bekummernis" 4. Modal Questions 5. Bach's Reflection on the Past: Moral Chorales in Cantata Designs 6. Two Chorale Cantatas 7. Cantata 77: The Theological Background 8. "Du sollt Gott, deinen Herren, lieben": An Analysis of Cantata 77 9. Epilogue: Cantata 60, "O Ewigkeit, du Donnerwort" Notes Bibliography Index


The aim of the current study is to study the effect of interferential current on pain and function of chronic low back pain patients. Research methodology: Twenty patients complaining from chronic low back pain lasting more than 3 months was randomly assigned into 2 equal groups. Experimental group which received interferential current in addition to medical treatment and control group which received only medical treatment. The main outcome measures of the current study was present pain intensity (PPI) measured by McGill Pain Questionnaire and function measured by Roland-Morris Disability Questionnaire. the current study showed that there was a signicant difference between control group and interferential group regarding present pain intensity and disability index. Conclusion and recommendations: We conclude that the addition of interferential current to medical treatment in the management of chronic low back pain is essential and effective.


The rapidly increasing complexity of societal systems increases the need for professionalism in management—one must be able to function reliably regardless of increasing management complexity in the twenty-first century. Malik's book is written for practitioners who bear responsibility for overall governance of the organizations and who are determined to carry out their tasks diligently, correctly, and well. It is intended, above all, for those who do not content themselves with fulfilling legal diligence duties, but who strive for entrepreneurial success—nothing less.


This paper aims to generate the most electricity on a solar board. A hemisphere suntracing-module composed of small solar boards is established. According to the electrical voltages of the small solar boards, the coordinates (angles) of the solar board with maximal electrical voltage will be recognized by the server port. With this, the server port will send the information to the client ports (the solar energy generation stations) via the internet. The client ports that wirelessly (with Wi-Fi module) connect to the individual microcontroller will direct the microcontroller to trigger two step motors to rotate to the related coordinates. All the main solar boards will be simultaneously adjusted to the best direction to generate the maximal solar electricity. The generated electricity will be stored in the related storage battery. For every time interval, the new coordinate will be recognized by the sun tracing module and then forwarded to the solar energy generation stations. The time interval can be predetermined on the server port.


This paper aims to describe digital literacy by utilizing the edlink application module in online lectures for Guidance and Counseling Study Program students, FKIP University, PGRI Mahadewa Indonesia. Utilization of technology is not new for students and in almost every activity can not be separated from technology products. Thus, the Guidance and Counseling Study Program lecturer must also be able to use or create information and technology-based learning media. Among the intermediaries or learning media is the edlink application module. With this media, lecturers can provide lecture materials that can be accessed by students and package their learning activities by utilizing the features available in Edlink and based on digital literacy. The use of edlink by lecturers provides students with experience in selecting and analyzing the information needed in online lecture activities. The stages contained in digital literacy include digital competence, digital use, and digital transformation. In general, this article will explain about the edlink application module, digital literacy, and online lectures through the digital literacy-based edlink application module.


Typically discussed in the context of optics, caustics are envelopes of classical trajectories (rays) where the density of states diverges, resulting in pronounced observable features such as bright points, curves, and extended networks of patterns. Despite the apparent complexity of such patterns, they are based on just a small number of fundamental forms described by the theory of catastrophe optics. Here, we demonstrate caustics in the matter waves of an atom laser, extending catastrophe optics to catastrophe atom optics. We showcase the generic forms of fold and cusp caustics, and exploit internal state manipulation to trace the flow of atoms. Atom optics affords new perspectives for fundamental science, metrology, atom interferometry and nano-fabrication techniques. Exploring the role of caustics in this context may lead to innovation as the generation of caustics is inherently robust, and leads to a variety of pronounced and sharply delineated features.


The transverse magnetic (TM) modes have long been considered as the unsuitable waveguide modes for the operation of the electron cyclotron maser (ECM). This study investigates the linear behavior of the TM modes and reveals for the first time that certain TM modes might be suitable for gyrotrons - ECM based devices. In addition, non-linear but non-self-consistent model shows that for a fixed field profile the efficiency could be as high as that of the transverse electric (TE) modes. Such interesting findings deserve more theoretical and experimental studies, and might facilitate some applications.


AIM: To investigate the effect of insulin on the transcriptional activtity of acyl coenzyme A: cholesterol acyltransferase 1(ACAT1) gene P1 and P7 promoters in THP-1 cells and THP-1-derived macrophages.METHODS: The human monocytic leukemia cell line THP-1 was chosen in the study.The differentiation of THP-1 cells into macrophages was induced by stimulating with phorbol myristate acetate(PMA) for 48 h.The luciferase reporter vector containing P1 or P7 promoter of ACAT1 gene was transfected into THP-1 cells by DEAE-dextran method.The luciferase activity was determined by dual-luciferase reporter assay system.Total RNA was extracted with TRIzol from THP-1 cells and THP-1-derived macrophages exposed to different concentrations of insulin for 24 h.The P1 transcript and P7 transcript of ACAT1 gene were detected by RT-PCR in THP-1 cells,and real-time RT-PCR with SYBR green I was used to quantitate the mRNA expression of ACAT1 in THP-1 cells and THP-1-derived macrophages.RESULTS: The transcriptional activity of ACAT1 gene P1 promoter and the relative expression level of ACAT1 gene P1 transcript significantly increased in a dose-dependent manner in insulin-treated THP-1 cells compared with the untreated cells,and no effect of insulin on P7 promoter was observed.Consistent with these results,real-time RT-PCR also showed that the expression level of ACAT1 mRNA was significantly up-regulated in a dose-dependent manner in insulin-treated cells in comparison with the untreated THP-1 cells and THP-1-derived macrophages.CONCLUSION: Insulin up-regulates ACAT1 gene expression by activating P1 promoter in a dose-dependent manner.


There is an ancient tradition, found in both the mainstream of Western philosophy and religion as well as Eastern thought that justice consists in giving people what they deserve - often rendered as giving each person his or her due. In our day desert, while still recognized by the ordinary person, has been undermined or completely dismissed by the leading political and social philosophers of our time. In this essay, I argue that its dismissal has been premature and while distinguishing "merit" from "desert" argue that both have a central place in moral and political philosophy as defining justice.


One of the glycosides of Vallaris solanacea has been identified as O-acetyl-solanoside (O-acetyl acofreosyl-digitoxigenin). It possesses potent cardiotonic activity. Its pharmacological properties have been compared with those of lanatoside C and digoxin.


Abstract Let p and q be odd primes such that Let F be the field with p elements and be a group, where A is an abelian group of order In this article, we prove that if then G does not have a normal complement in Further, for any integer we prove that if F is a finite field such that then and do not have a normal complement in and respectively.


© 2007 Human Kinetics • Att 12(5), pp. 14-16 PPER EXTREMITY deep vein thrombosis (UEDVT) is a rare condition among athletes. Initially reported in the late 1800s as primary axillary-subclavian thrombosis, the incidence rate of UEDVT is approximately 2 per 100,000 persons per year.1,2 UEDVT may be due to trauma, intravenous drug use, improper catheter placement, or may be effort-related.1,3 Anatomical anomaly of the costoclavicular region, such as cervical ribs and/or anomalous muscular insertions, are often associated with UEDVT. Athletic victims of UEDVT are typically involved in sports that require forceful overhead motions, such as baseball pitchers, weight lifters, and tennis players.1 Diagnosis, management, and treatment of UEDVT is controversial.1-6 UEDVT is rare, but is responsible for 3-6% of all pulmonary emboli and 1-2% of all fatalities from pulmonary emboli.1 The purpose of this report is to present a case of UEDVT, highlighting the clinical presentation, evaluation, management, and current medical opinions about this condition.


Abstract Calcareous deposits were formed on steel under cathodic protection conditions in artificial sea water at various potentials from −0·900 to −1·400 V(SCE). The deposition calcareous layers were characterised by electrochemical impedance spectroscopies, scanning electron microscopy observations and X-ray diffraction analyses. At 20°C, the deposits were composed of calcite CaCO3 when formed at various potentials in solution 1, of brucite Mg(OH)2 and aragonite CaCO3 when formed at potentials from −0·900 to −1·200 V(SCE) and only of brucite when formed at potentials E⩽−1·300 V(SCE) in solution 2. Magnesium seems to influence the corrosion behaviour of freely corroding steel by causing calcium carbonate to precipitate as aragonite. Aragonite is more effective in covering the surface than calcite and is therefore more functional in preventing oxygen from reaching the steel surface, thereby lowering the corrosion rate.


Two geostationary satellites developed by the Korea Aerospace Research Institute and currently in operation are the GEO-KOMPSAT-2A (GK-2A) and the GEO-KOMPSAT-2B (GK-2B). The main instruments mounted on these satellites are the Advanced Meteorological Imager (AMI), the Geostationary Ocean Color Imager (GOCI-II) and the Geostationary Environment Monitoring Spectrometer (GEMS). This paper briefly introduced the GK-2A and GK-2B programs including measurement principles and elements of the instruments. Moreover, the data formats, operational products, and applications are summarized.


Spins by the mirror, trimmed in copper rivets and flashing indigo. Meantime Mom fidgets like she is ready to make a call, while we teenagers look on, remembering crystal goblets, pointed shoes, tomato salads, not this sashay under ultraviolet lights in the Army Navy when just days before she was in Clarksburg wearing tan bend-overs at her kitchen table with the burner left on, singed curtains flying out the open window and grandaddy refusing to leave the golf course.


The vast perspectives of our country's development as outlined in the decisions of the 22nd Party Congress and the new Party Program envisage the education and development of the new man - the man of the communist future - as one of the basic tasks before us. The school is one of the channels for the communist education of the rising generation, and so it is no accident that the question of the organization of our schools holds the attention of the Party, the government, and wide scientific circles. This organization, as well as the content and methods of school work, are questions of interest not only to educators but also to wide circles of scientists in the most varied fields; they are discussed not only in the pages of pedagogical journals but also in the daily press, in magazines, even in books which at first sight do not seem to have any direct relation to education and instruction.


Expressway is a key element in urban network.How to take reasonable style of express and make full use of it,to put forward to city?Hence,this paper analyzes and concludes this question based on some examples in practice.


A problem facing anthropologists, given the centrality of memory and imagination to all social life, is how to access memory and the imaginary when there is no independent access to consciousness. Moreover, the discipline has 'largely failed to distinguish itself' in response to understanding HIV/AIDS (Annual Review of Anthropology30, 2001: 163). In response to these observations I would argue that orthodox approaches are limited and we need to create new forms of collaborative research and representation with regard to understanding experiences of illness. Accordingly this article attempts to bring to life the interior dialogue of persons living with HIV/AIDS through performance by 'mapping' the city of Kampala through its emotions and memories rather than buildings and streets.


Background and Objective: The Author of this Article wants to show the importance of the Public Health Intervention, Preventions against the COVID-19 novel corona virus. The use of WHO methods of Preventions such as Isolation & Quarantine, Using PPE, washing hands regularly, Cover the mouth during cough would help to control COVID-19 Pandemic. Methods: The Author of this article has randomly selected 15 Articles from PUBMED and other sources on net with the word using "Public Health Preventions for COVID-19". The Author relies on Conceptual Literature Review for the Methodology of this article. Where the groups of Articles are reviewed and analysed to find out the answer of the Question "Study favor or Ignores the Public Health Preventions to reduce the Infection in the Article". The Table 1 is created to Analyse the 15 randomly selected Articles and the results has been presented By SPSS software diagrammatic presentation. Results: According to the SPSS Diagrammatic presentation, the results of 15 randomly selected articles indicates that all 15 articles favor Public Health Preventions to reduce the COVID-19 Infection. Secondly, 10 articles agreed 100% on Public Health Preventions to reduce the COVID-19 Infection in the community and 5 articles shows lower percentages. The given Table 1 clearly gives the information and references of 15 randomly selected articles for the study discussed here "Study favor or Ignores the Public Health Preventions to reduce the Infection in the Article". Conclusion: Global Health and other organizations such as WHO, UNHCR, UN, UNESCO, UNICEF did not act fast to Prevent and Control the COVID-19 Pandemic. Other Governments of the countries in the world act very slowly for the warnings given by WHO and other scientists. Later since November 2019 till now approximately 350,000 people have lost their lives due to COVID-19 and approximately 5 Million people are infected by this COVID-19 disease. Lessons should learn from COVID-19 Pandemic and it is not over yet as scientists predicts that COVID-19 is with us for next couple of years. The vaccine of COVID-19 is under development and there is not exact treatment for COVID-19 by medical sciences till now.


Diseases are increasing in marine ecosystems, and these increases have been attributed to a number of environmental factors including climate change, pollution, and overfishing. However, many studies pool disease prevalence into taxonomic groups, disregarding host-species composition when comparing sites or assessing environmental impacts on patterns of disease presence. We used simulated data under a known environmental effect to assess the ability of standard statistical methods (binomial and linear regression, ANOVA) to detect a significant environmental effect on pooled disease prevalence with varying species abundance distributions and relative susceptibilities to disease. When one species was more susceptible to a disease and both species only partially overlapped in their distributions, models tended to produce a greater number of false positives (Type I error). Differences in disease risk between regions or along an environmental gradient tended to be underestimated, or, even in the wrong direction, when highly susceptible taxa had reduced abundances in impacted sites, a situation likely to be common in nature. Including relative abundance as an additional variable in regressions improved model accuracy, but tended to be conservative, producing more false negatives (Type II error) when species abundance was strongly correlated with the environmental effect. An analysis of field data on bleaching from the Florida Keys, FL, USA, affirmed general results of model simulations. Investigators should be cautious of underlying assumptions about species similarity in susceptibility and species composition when interpreting pooled data on disease risk.


It provides a method performed by an embedded system, the embedded system can be controlled by the CPU and the system as a virtual management program under the supervision of the operation, or as a non-virtualized operating system under the supervision of the operating system. If the embedded system does not need to perform any safety-critical functions, run the embedded system in normal mode, wherein execution of the normal mode operation under the supervision of the operating system. If the embedded system needs to perform safety-critical functions, by the operating system by running the embedded system transfer from the operating system to manage the program, to be run embedded system to switch from normal mode to protected mode, which, in the management of the program execution Prevention mode operation under the supervision of, and when the embedded system is no longer required to perform safety-critical functions, under the supervision and management of the program, will run the embedded system to switch from protected mode to normal mode.


Abstract The basic equation of motion of structural members with a thin-walled cross-section under periodic follower torque and force becomes a Mathieu's equation and simple parametric and combination resonances occur in this system. The regions of those resonances of the members with various boundary conditions are estimated by using the stability criterion with the characteristic exponent and their instability becomes evident from the numerical results.


As I was writing this review, Kim Davis was taking a stand in Kentucky. A committed Christian and the duly elected clerk of Rowan County, Davis was refusing to issue marriage licenses to same-sex couples, despite the U.S. Supreme Court's recent ruling. In her vocal refusals to issue the licenses, Davis enacted a stance that was at once marginal and universal. It was marginal in that Christianity was under assault by a few unelected judges and by supporters of the gay, liberal agenda. It was universal in that she operated in the light of universal truth, beholden to a Power that no court could nullify. In adopting this marginal–universal stance, Davis was acting as part of a fundamentalist counterpublic—a combative religiopolitical tradition that Jonathan Edwards takes up in Superchurch: The Rhetoric and Politics of American Fundamentalism. Though the details of fundamentalist combat have changed over the years, explains Edwards, fundamentalism writ large "has been and remains a part of this messy, contentious political process, calling for true believers to gather in defense of its speech and ideals and in offense against its enemies" (182). It was this call Kim Davis heeded in her opposition to same-sex marriage. For many of us academics, it may be tempting to dismiss Davis and her supporters as fundamentalist fanatics. But Superchurch cautions us against such a dismissal, telling the story of a disruptive, complex, and successful counterpublic that demands scholarly understanding. Carefully researched, expertly argued, and richly detailed, Edwards's book provides an insightful account of a mode of political engagement that has long shaped and will continue to shape American public culture.


IntroductIon: - Nasal polyposis is regarded as one form of chronic inflammation in the nose and sinuses as part of the spectrum of chronic rhinosinusitis. The management of nasal polyposis has been the topic of frequent controversial debates for many decades .Management of nasal polyp should be primarily based on a medical approach to be completed by surgical procedures. In this present study we are relating our experience of surgical management of nasal polyposis at government general hospital Kurnool. Materials& Methods : This isa prospective study of sinonasal polyposis who presented with nasal obstruction/discharge in ENT opd in government general hospital kurnool from June 2013 to May 2015(2 years). Results - Most of cases are diagnosed with Antrochoanal polyp followed by Ethmoidalpolyp.The complication rate was less. In 3cases there was  bleeding during surgery and  2 cases were postoperative complications like synechiae formation. In followup95% cases symptoms free at the end of 6 th month postoperatively. There is less recurrence rate of nasal polyposis in our study i.e 5%. Conclusions: Thus this study substantiatedendoscopic management of nasal polyp is the best available modality of treatment of nasal polyposis.


The Anchored Separated Representation for High Dimensional Problems Matthew Tin Chun Li Master of Applied Science Graduate Department of Aerospace Engineering University of Toronto 2015 Although topics in science and engineering that involve dimensions beyond x-y-z appear obscure, in truth numerous examples abound. For instance, uncertainty quantification requires approximating and integrating functions with many inputs, while the study of non-linear random vibrations involve PDEs whose dimensionality scales with the system's degrees of freedom. Such problems are numerically difficult since the application of classical mesh based techniques incur computational demands that scale exponentially with the dimension; this is the curse of dimensionality. In this thesis we formulate two tractable numerical methods that circumvent this curse by assuming sparsity in the model representation. The first method, the anchored separated representation, is a provably minimal decomposition for functions that are sparse in a multiplicative sense. The second method is an iterative extension for approximating functions that are sparse in rank. We illustrate with numerical examples the application of both methods to a broad class of high dimensional problems.


In the current scenario of educational institutions, multimedia has dig up its own kind of space in some or the other way as a tool of educational technology. Multimedia has overcome the barriers of time and space and provides evidence to be accepted as an anytime and anywhere tool for educating multi-disciplinary masses. The process of knowledge acquisition becomes more efficient when the learners experience an event through a multimedia simulation. Multimedia technology empowers the educational process by means of increased interaction between teachers and the students. Apart from the fact that multimedia can provide educators and students with endless possibilities of quality teaching and learning, taking vital considerations of the pedagogical strengths and limitations of Multimedia, it can be used to its fullest potency, and reach the eminence of 'New Educational Technology tool'. This paper presents a comprehensive study of selected papers that are pertinent to the use of Multimedia in Education, as well as lists down the various proposed multi-disciplinary educational frameworks and tools for the same. In this paper, a study of most commonly used methods and issues related to the use of Multimedia as a new education technology tool has been carried out and reported. It also presents a categorized listing of such papers, accompanied by annotations that describe the content of the papers and their relevance to the use of Multimedia in Education.


Researchers at the Weizmann Institute of Science have shown for the first time that systemic immune suppression may contribute to neuroinflammation, brain pathology and cognitive dysfunction in Alzheimer's disease (AD), and that by taking the brakes off of peripheral immunity, companies may be able to develop therapies that recruit macrophages and T cells to treat the disease. While the results only sketch the outline of the mechanism, they point to a central role for T regulatory cells (Tregs) in the process, making the cells a target for intervention. Michal Schwartz, professor of neuroimmunology at Weizmann and principal investigator on the study, told BioCentury her group's findings upend the long-standing dogma that "reducing inflammation within the CNS always requires immunosuppression." Instead, she said the results "suggest that reducing inflammation in the brain requires boosting an immune response outside the CNS, to facilitate recruitment of immunosuppresive cells to the inflamed brain." Chronic neuroinflammation is thought to be a secondary feature of AD, in which ongoing deposition of Aβ persistently activates microglia and astrocytes — cells thought to mediate neuroinflammation through release of proinflammatory cytokines and other mechanisms. Unlike neuroinflammation caused by acute injury or infection, which is typically transient, the inflammation in AD isn't resolved because the activated glial cells can't clear the Aβ as fast as it is deposited. The result is that the accumulated Aβ damages synapses and neurons, inducing more inflammation in an escalating cycle. To break the cycle, researchers have largely focused on clearing Aβ, modulating microglial responses or inhibiting inflammation with steroids and NSAIDs. But because inflammatory responses in tissues outside the brain can only be turned off via an active process involving recruiting immune cells with anti-inflammatory activity, Kuti Baruch, a postdoctoral researcher in Schwartz's lab and first author on the study, hypothesized that the same might be true inside the brain. In testing that idea, Schwartz said, "we found that transient depletion of regulatory T cells not only stops the progression of the disease, but could reverse some of the disease symptoms in a very dramatic way." While noting many details still need to be ironed out, she proposed a mechanism that centers on the role of Tregs in controlling the status of the choroid plexus — the epithelial barrier between the blood and CSF. In healthy brains, the choroid plexus acts as a site of immune surveillance that allows immune cell entry to the brain in response to acute injury or inflammation. But in AD, according to her team's working model, Tregs suppress that transition and prevent immune cells from the periphery from being recruited to help resolve the inflammation inside the brain.


The first in a new series, this introductory text outlines what is meant by excellence in practice and explores the core contemporary issues used to illustrate excellence, including evidence-based practice, clinical governance, and health and social care standards. McSherry and Warr offer simple and effective tools and techniques to support the development of excellence in practice. The book also provides guidance to support the individual, team and organisation in achieving excellence in practice. All topics covered are key to the Quality and Modernisation agendas, and the book includes coverage on: reshaping healthcare delivery; clinical governance; responsibility and accountability; implementing government targets and National Service Frameworks; public confidence; partnerships and collaborative working; equality and diversity; autonomy; and, recruitment and retention.Real life practical examples and reflective exercises are used throughout to help the reader explore what excellence means in their everyday practice, as well as enforce the theory needed to inform delivery of excellence. "An Introduction to Excellence in Practice Development in Health and Social Care" is key reading for nurses and health and social care professionals, both in training and in practice.


After years of struggle and competition,Translatology became the discipline.The disputes between translation scholars both at home and abroad reveal the incongruence between its name and nature while giving the discipline an opportunity for unprecedented development.Observations from a logical point of view find that this dilemma arises from multi-understandings of the concepts the term Translatology denotes,which constitutes the starting point of this article.Conforming to formal-logical principles,drawing from extensive literature,and employing the Western traditional philosophical dichotomy between the Subject and the Object,the article puts forward a new 4-level scheme of Translatology,with its focus on the three kinds of elements of translation phenomena,i.e.participants,events,and tangible materials.Areas for further research are identified.


Both traditional wireless sensor networks and novel crowdsensing techniques generate tremendous real- time data, which provides great opportunities for real- time and long-term analytics. However, how to integrate the heterogeneous data sources and create data analytics toolboxes that can be connected together to solve various problems in urban environment remains open problems. As a PhD student, my research interests include: (1) Creating robust sensing mechanisms to integrate heterogeneous data sources that often vary in sample rates, sizes, and formats, and suffer from missing, duplicated and faulty data issues, (2) Building robust toolchains of analytics classes, (3) Developing applications that utilize the data and toolchains.


Topological order of magnetic films shows promise due to its unconventional electromagnetic transport effects, but the discontinuity and the miniaturization of patterned magnetic films impose a limit on research of topological properties. In this article, a technique is proposed, the application of which improves the ease of electrical measurement in sub-micrometer-sized magnetic thin film elements. To obtain the topological Hall resistivity of the discretized magnetic textures, a ferromagnetic bilayer film was fabricated into specific geometries. Micromagnetic simulations are presented that demonstrate the topological spin distribution in an exchange coupled patterned ferromagnetic film. Experiments are performed on FePt/FeNi bilayered films that are formed with square arrays of FeNi disks on top of a continuous FePt film in a topological spin distribution. The observation of topological Hall effect was made in the FePt/FeNi film without a nanoscale Hall-bar device. The technique presented facilitates the electrical property measurement even in nanometer elements and offers a pathway for promoting spintronics applications.


The possibility that diffuse idiopathic skeletal hyperostosis (DISH) could be a complication of isotretinoin therapy was not appreciated until after the drug had been introduced. We report 120 patients with acne, who were X‐rayed within 1 year of a 4‐month course of isotretinoin (mean dose 0·5 mg/kg/day). Since DISH is an age‐dependent disease, we compared the data with age‐matched controls who were X‐rayed for a non‐significant soft tissue injury.


Background : Human immunodeficiency virus (HIV) affects the kidney. Urine screening for abnormalities can detect early renal parenchymal diseases. Objectives : To determine the prevalence of abnormal urinary findings in HIV positive children in University of Nigeria Teaching Hospital, (UNTH), Enugu. Method : Urinary screening was carried out in 159 HIV positive children in UNTH over a period of 4-months, to detect presence of abnormalities such as glycosuria, proteinuria, haematuria, as well as the presence of nitrite and leucocyte esterase, abnormal urine pH and specific gravity (SG). Results : Eighty males and 79 females were screened. Five (5), 4, and a child had proteinuria, SG of > 1.015 and alkaline urine, giving a prevalence rate of 3.1%, 2.5% and 0.6% respectively. Neither of the subjects had glycosuria, haematuria nor tested positive to nitrite and leucocyte esterase. Subjects with proteinuria were older (5-14 years), had longer duration of HIV diagnosis, longer duration of treatment with HAART, and a lower CD4 cell count (p=0.01). Sixty percent of those with proteinuria had severe immunosuppression, with 4 out of the 5 of them with urine SG more than 1.015. The children with urine SG more than 1.015 were among the older age group (5-14 years), on HAART, had non-advanced HIV disease as well as low CD4 cell count (p= <0.0001). Conclusion : Urinary abnormalities occur among HIV infected children. Longer duration of HIV diagnosis, older age and low CD4 cell count, are probable factors associated with proteinuria.We recommend routine urinary examination for HIV positive children.


Ethereum, a leading cryptocurrency, is advancing the way we handle digital transactions. One important concept in Ethereum is "account abstraction," which could play a crucial role in making it accessible to a wider audience. Currently, Ethereum has two types of accounts: externally owned accounts (EOAs) and contract accounts (CAs). EOAs are controlled by a public address and private key, allowing users to initiate transactions and interact with smart contracts. However, losing the private key can result in the loss of funds, and EOAs are not quantum safe. On the other hand, CAs are controlled by the code written on the Ethereum Virtual Machine (EVM) and do not possess private keys. They rely on network storage, and their creation incurs a cost. To enhance the existing technology and make it more user-friendly, there is a proposal for "account abstraction" in the Ethereum protocol. This change would enable users to interact with smart contracts using smart contract wallets instead of externally owned accounts. This would bring greater flexibility and security to the management of user accounts, as well as open doors for new and innovative user experiences.


Accountability comes from the field of public administration.In the wave of educational democratization,accountability has been adapted into the education management system,especially in the British-American higher education management.Analyzing accountability in the British-American,the paper provides some tactics to construct accountability of higher education institutions in China from the point of view of institution construction.


Our paper focuses on studying drivers of individual drug user relapse as well as broader systematic drug use patterns across states in the United States of America. For this study, two datasets were used; the first is a subset of the survey results from Dr. Miriam Boeri's co-authored study, "Older Drug Users: A Life Course Study of Turning Points in Drug Use [in a large Southeastern Metropolitan Area], 2009-2010". The dataset included variables such as the gender, race, education level, the age at which the respondents moved away from their guardian's home, and the age at which the respondent filled the survey. With this dataset, a logistic regression analysis is preformed to identify factors that may be associated with drug relapse. We found that the only "somewhat important" factor, as compared to all the factors studied, seemed to be "the current age of the respondent when they interviewed."The second dataset is composed of variables such as the state-wise population density, GDP, median household income, opioid prescription rate, death rate due to overuse of opioids, alcohol consumption rate, death rate due to alcohol overuse, death rate due to drug overuse, suicide death rate, and education attainment level across the United States.


It is an inherently challenging task to provide quality of service (QoS) to real time multimedia users in a cellular network owing to their mobility induced uncertainty. We propose an implicit resource allocation strategy and justify the need of such a strategy toward an effective solution to QoS provisioning. The reservation scheme presented, based on this proposed strategy, aims at meeting the users' QoS requirement while maintaining a better utilization as compared to the conventional resource reservation schemes. Simulation results are presented which show the effectiveness of the scheme under a varying level of user mobility.


Managing intrahospital emergencies requires organizational and qualitative preparatory preliminaries. The reanimation quotas are often used to show the success of the preparatory work. They may possibly be improved by introducing early defibrillation programs. In such cases it is imperative to ensure that the potential users are sufficiently well trained. For optimal patient care it is most useful to provide for additionally uniform equipment, such as a resuscitation cart including an automated external defibrillator. The quality of emergency care of a patient can also be improved by means of an emergency call by means of a reanimation team that can be informed via a central emergency call number. Externally introduced emergency patients are accepted to a (central) emergency reception unit, High quality competency of intrahospital emergency care can be ensured only if all of these measures interlock without a hitch.


Small business lending by community banks has fallen in recent years due to community banks being acquired by larger counterparts (Jagtiani and Maingi, 2018). Regulatory requirements have incentivized larger banks to acquire smaller banks (Bonilla et al., 2018). To compete against larger competitors, community banks are taking a relationship based approach to lending (Bonilla et al., 2018). These institutions are uniquely suited for small business loans in that they know their community and their client base. The purpose of this paper is to examine a small community bank and assess their small business lending.


The principles,advantages and disadvantages on recent treatment technology of ammonia-nitrogen wastewater were overviewed.The research status at home and abroad was introduced.The prospects of ammonia-nitrogen wastewater treatment was looked forward and considerable problems for the future were proposed.


Orbital collisions pose a hazard to space operations. Using a high performance computer modeling and simulation environment for space situational awareness, we explore a new paradigm for improving satellite conjunction analysis by obtaining more precise orbital information only for those objects that pose a collision risk greater than a defined threshold to a specific set of satellites during a specified time interval. In particular, we assess the improvement in the quality of the conjunction analysis that can be achieved using a distributed network of ground-based telescopes.


Due to the complexity of low-permeability reservoirs, there is no set of established plans to adjust the development of specific low-permeability reservoirs, and the final development adjustment plan should be determined through comprehensive consideration of many aspects. At present, the development of low-permeability reservoirs in the SN oilfield faces problems. It is urgent to formulate corresponding development adjustment plans to improve the current development situation. In view of the problems of the current development surface of low-permeability reservoirs in the SN oilfield, this paper used the previous research results of a low-permeability reservoir development adjustment for reference, evaluated the reservoir development effect, analyzed the remaining oil distribution via numerical reservoir simulation, and finally designed and optimized a development adjustment plan. The research results show that the injection–production ratio and pressure of low-permeability reservoirs in the SN oilfield were generally maintained, the oil production decreased, the water cut increased, and the remaining recoverable reserves were considerable; the historical matching quality of a reservoir numerical simulation was good. There was more remaining oil in the northeast of the J007 well block and the north of the J008 well block, and the potential of the L2 and L3 layers was great. The remaining oil was mainly concentrated in the areas with high positions, poor physical properties, and imperfect well patterns; the predicted cumulative oil production of Scheme IV in 15 years and recovery were the highest, with the best development effect and the highest economic benefit. This was determined as the development adjustment plan for low-permeability reservoirs in the SN oilfield. The research results of this paper aim to improve oil production, the ultimate recovery factor, and economic benefits of low-permeability reservoirs in the SN oilfield, and to provide a reference for the development of similar oilfields.


The present disclosure relates to a ventilation pad, and more particularly, to a ventilation pad for a toddler carrier, which is installed inside a toddler carrier such as a baby sling, wherein a three-dimensional mesh pad having a sufficient predetermined thickness is inserted between a mother and a baby, thereby alleviating heat and preventing discomfort when using a baby sling or carrier during the summer months.


Background: Identification of high-risk groups is needed to inform COVID-19 vaccine prioritization strategies in Canada. A rapid review was conducted to determine the magnitude of association between potential risk factors and risk of severe outcomes of COVID-19. Methods: Methods, inclusion criteria, and outcomes were prespecified in a protocol that is publicly available. Ovid MEDLINE(R) ALL, Epistemonikos COVID-19 in LOVE Platform, and McMaster COVID-19 Evidence Alerts, and select websites were searched to 15 June 2020. Studies needed to be conducted in Organisation for Economic Co-operation and Development countries and have used multivariate analyses to adjust for potential confounders. After piloting, screening, data extraction, and quality appraisal were all performed by a single reviewer. Authors collaborated to synthesize the findings narratively and appraise the certainty of the evidence for each risk factor-outcome association. Results: Of 3,740 unique records identified, 34 were included in the review. The studies included median 596 (range 44 to 418,794) participants with a mean age between 42 and 84 years. Half of the studies (17/34) were conducted in the United States and 19/34 (56%) were rated as good quality. There was low or moderate certainty evidence for a large ([≥]2-fold) association with increased risk of hospitalization in people having confirmed COVID-19, for the following risk factors: obesity class III, heart failure, diabetes, chronic kidney disease, dementia, age over 45 years (vs. younger), male gender, Black race/ethnicity (vs. non-Hispanic white), homelessness, and low income (vs. above average). Age over 60 and 70 years may be associated with large increases in the rate of mechanical ventilation and severe disease, respectively. For mortality, a large association with increased risk may exist for liver disease, Bangladeshi ethnicity (vs. British white), age over 45 years (vs. <45 years), age over 80 years (vs. 65-69 years), and male gender in those 20-64 years (but not older). Associations with hospitalization and mortality may be very large ([≥]5-fold increased risk) for those aged over 60 years. Conclusion: Among other factors, increasing age (especially >60 years) appears to be the most important risk factor for severe outcomes among those with COVID-19. There is a need for high quality primary research (accounting for multiple confounders) to better understand the level of risk that might be associated with immigration or refugee status, religion or belief system, social capital, substance use disorders, pregnancy, Indigenous identity, living with a disability, and differing levels of risk among children. PROSPERO registration: CRD42020198001


The tenrec (Tenrec ecaudatus ; Order : Insectivora; Class : Tenrecinae ) is consumed by a small section of the population, and constitutes a non-conventional  source of animal protein. Male tenrecs were hunted in early October and in late November, and a comparison in carcass composition was made between the two periods. The carcasses of males hunted early in the hunting season showed a higher fat content (P<0.05), compared to males hunted in late November. Adipose fat was dissected in similar depots (subcutaneous, suprarenal and mesenteric fat) at both periods, but the total weight of adipose fat was significantly higher in males hunted in early October, compared to late November (36.16g vs 7.89g; P<0.01). There were no fat depots around the heart at both periods. The total weight of edible meat yield was significantly greater in male tenrecs hunted in early October (P<0.05). Keywords : Tenrec ( Tenrec ecaudatus) , male, carcass quality, non-conventional meat protein.


This paper discusses a theory of the neocortical algorithm called the hierarchical temporal memory (HTM). Hierarchical temporal memories are built around a hierarchy of nodes. The hierarchy and how it works are the most important features of HTM theory. In an HTM, knowledge is distributed across many nodes up and down the hierarchy. As an HTM is trained, the low-level nodes learn first. Representations in high-level nodes then share what was previously learned in low-level nodes


We examined the distribution of Umpqua Chub Oregonichthys kalawatseti, an endemic, vulnerable minnow in western Oregon, and whether six ecological populations (based on distribution patterns) had sufficient genetic cohesion to be considered evolutionary populations. We also evaluated the influence of Holocene geological events and recent nonnative predator introductions on the timing of population formation or fragmentation. Based on data from 10 microsatellite loci, we found evidence for four evolutionary populations of Umpqua Chub. One population, in the Smith River, is isolated by the Umpqua estuary and is more than 100 river kilometers from the other three populations: Elk Creek, Calapooya Creek–Olalla Creek, and Cow Creek–South Umpqua River. Quantile regression was used to examine the timing of genetic divergence among evolutionary populations assuming a genetic isolationby-distance model. The quantile regression suggested that the genetic differentiation index (FST) should change by at least 0.0002/km; most fragmentation was recent and with similar timing, but the Smith River isolation event may have been about 2–4 times older. We could not distinguish whether the timing of the Smith River isolation corresponded to the last major tsunami event or the introduction of Striped Bass Morone saxatilis, a likely predator. All population fragmentation appears to be relatively recent, with the three upstream populations restricted to thirdand fourth-order streams, most likely fragmented by either nonnative Smallmouth Bass Micropterus dolomieu, which now dominate sixth-order streams, or in the case of Elk Creek, a dam. The mid-drainage Calapooya–Olalla population was the most genetically diverse and appeared to be a mix of the other populations, which showed a significant isolation-by-distance relationship to this population. We hypothesize that Umpqua Chub populations have formed and fragmented by peripheral isolation from a larger population, the remnant of which is the mid-drainage Calapooya–Olalla population. The genus Oregonichthys is composed of small minnows endemic to western Oregon. One such member, the Oregon Chub O. crameri, from the Willamette River is listed as threat*Corresponding author: firstname.lastname@example.com Received April 20, 2012; accepted August 25, 2012 ened under the U.S. Endangered Species Act (USFWS 2010); another, the Umpqua Chub O. kalawatseti from the Umpqua River, is considered a "sensitive–critical species" by the Oregon 447 D ow nl oa de d by [ O re go n St at e U ni ve rs ity ] at 0 9: 37 1 5 A pr il 20 13


A new thiosemicarbazone compound derived from 1-phenyl-3-methyl-4-(2-thenoyl) pyrazolone-5 (HPMTP) and thiosemicarbazide has been synthesized and characterized by IR, HNMR, MS, elemental analysis, UV and single-crystal X-ray diffraction. The compound crystallizes in monoclinic system, Cc space group with a = 7.5925(8), b = 20.263(2), c = 11.4669(13) A, β = 107.825(8)°, V = 1679.5(3) A, Z = 4, R = 0.0316 and wR = 0.0687. The results of antibacterial activity test against Escherichia coli and Bacillus subtilis indicate that the compound possesses the same antibacterial activity as the contrast (Norfloxacin). Theoretical study of the forming mechanism to the title compound at the RHF/6-31G(d) level shows that there are two steps. The distal amino group of thiosemicarbazide is added to the 4-carbonyl group of HPMTP which forms TM. Then a dehydration reaction occurs in TM and generates a stable product PC.


Yangtse and Yellow River drainage area are prone to form serious flood waterlogging disaster.According to the data analysis of flood waterlogging disaster in Yangtse and Yellow River drainage area,by using commensurability of informative forecast theory,the tendency of the next flood waterlogging disaster is predicted.The conclusions indicate that the strong disaster of biggish flood waterlogging disaster will probably occur in 2008 and 2013 at Yangtse River and in 2012 at Yellow River.These messages are expected to offer an important referenced datum for the purpose of disaster prevention and reduction.


The orthopantogram taken from TMD patients were analyzed whether they had vertical asymmetry of mandibular ramus using Habet's formula. Among them, 37 patients with asymmetry were selected from subjects for asymmetry group and 43 patients without asymmetry for symmetry group. The difference in treatment outcome were studied between two groups and the results were as follows.
1. There were no significant difference in duration of illness and duration of treatment between asymmetry and symmetry group.
2. There was no significant difference between asymmetry and symmetry group according to diagnosis.
3. In the comparison of variable parameters presenting the extent of TMD symptoms before treatment, only the severity of pain was significantly higher in asymmetry group than symmetry group. After treatment, there were no significant differences in variables; pain, noise, limitation of opening and maximum comfortable opening.
4. Considering the changes on joint noise as an objective parameter after treatment, there was no significant difference between asymmetry and symmetry groups.
5. Between asymmetry and symmetry groups, there was no difference in employment of conservative treatment protocol to obtain the similar treatment outcome.
Based on this study, it can be concluded that conservative, reversible treatment resulted in same outcome for TMD patients having asymmetry of mandibular ramus.


In recent years, there has been a sharp increase in public and scientific attention to environmental monitoring. This is due to the increase of man-made load on the environment and, first and foremost, the geological environment, as well as the need for new, higher organizational and technical level to solve the problems related to its changes. Recent monitoring data indicate a tendency to intensify this negative natural-technogenic process on a spatial-temporal scale and increase, first of all, the areas of flooding, as well as subsidence, landslides and other dangerous phenomena. Accordingly, during the operation of buildings, under the influence of the above factors, the corresponding new stress-strain state of the system "basefoundation-upper structure" changes and forms. In many cases, this leads to damage to building structures, emergencies and a significant decrease in the reliability of buildings. Today in Ukraine 10 962 dwellings are in a state of disrepair. The example of geotechnical monitoring in the town Kyiv is presented in the article. The specially developed monitoring program included: geodetic control of deformations of buildings of the surrounding building and structures of the reconstructed building; systematic observation of deformations of structures in the process of excavation of the pit and construction, with the installation of inclinometric sensors, deformation beacons and geodetic marks; observation of groundwater level fluctuations during construction; observation of the state of deformation beacons installed on the cracks of buildings of surrounding buildings; engineering-geological monitoring to ensure confirmation of the physical and mechanical characteristics of the soil of the bearing (support) layer of pile foundations and piles of reinforcement. Geotechnical monitoring made it possible to preserve the existing historical buildings in the area of influence of the geotechnical works on the Poshtova Square reconstruction in Kiev, to eliminate the risk of emergencies.


The 1991 accession to independence has been a surprising and traumatic event for the new Republics of Central Asia. The disapparence of the Soviet political and economic system has not only produced a socio-economic crisis in the region but has also questioned the ways the West has approached this region of the world. In fifteen years the relations between the West and Central Asia have gone through different phases : « discovery », and then « disillusion » and disengagement. Since 2005 international cooperation is progressively marginalized and actors such as China, Russia or India are becoming the key actors for the development of the region.


Objective
To assess the impacts of management of psychological health on metabolic indictors in community residents.

Methods
A total of 300 health check-up adults from one single community were randomly assigned to the control group (receiving routine health management, n=150) and the study group (receiving psychological health management, n=150). Blood pressure (BP), fasting plasma glucose(FPG), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and life style were evaluated and compared at baseline and 1-year follow-up.

Results
No difference of clinical data was found between the two groups at baseline.After 1-year intervention, current sigarette smoking, BP, FPG, TC, TG and LDL-C of the study group were significantly decreased when compared with the control group (χ2=7.54, t=6.43, 5.38, 5.89, 6.15, 4.36, 6.69, 5.47; all P<0.05). Compliance to and satisfaction with health management were significantly improved in the study group (χ2=9.13, 12.35, 11.96, 10.98, 9.95; all P<0.05).

Conclusion
Management of psychological health may be effective in improving healthy life style, patients' satisfaction and cardiovascular metabolism in community residents.

Key words:
Community medicine; Psychology; Cardiovascular diseases; Health education


Male Wistar rats, weight from 170 to 190 grams, were divided into normal control group(NC), experimental control group(EC), experimental group 1 and 2 (E1 and E2). Two control groups were allowed to drank tap water, E1 and E2 were supplied with tap water containing 100 mgL 1 and 200 mgL 1 Momordica saponins respectively. After 5 weeks, plasma from the last three groups fasted for 24hrs were collected. Ther the rats were fed again and drawn plasma at postprandial 24 hr. Samples of muscle and liver were got after one week. Results: Momordica saponins could not affect the level of plasma insulin, but increase levels of glucose and cortisone significantly in fasting rats. And levels of plasma glucose and cholestrol were decreased obviously in two experimental groups postprandial. At the same time, Momordica saponins could raise the level of glycogen in muscle and liver in some extent.


In this paper, the load torque on the swashplate of axial piston variable displacement pumps with conical cylinder blocks is studied. At present, general analytical solution for the load torque of axial piston variable displacement pump is not available, which makes the dynamic analysis and controller design an uneasy work. The main contribution of this paper is that the analytical solution of the swashplate torque caused by piston inertia and centrifugal force was derived. First, based on the piston acceleration and centrifugal force, the piston kinematic and dynamic models were developed, the analytical solution of the swashplate torque caused by piston inertia and centrifugal force was derived. In addition, the piston chamber pressure dynamics were established, the pressure distribution in the cylinder bore and the load torque of the swashplate under different working conditions were obtained. Finally, the relationship between the swashplate average load torque and the swashplate angle, swashplate angular velocity, pump load pressure and the pump input shaft velocity was uncovered. It is shown that the swashplate angle has greater influence on the load torque when the pump load pressure is higher, besides, it is interesting to observe that the swashplate angular velocity has a damping influence upon swashplate dynamics which helps to stabilize the swashplate during pump displacement regulation transients.


The present invention discloses a method of evaluation of fracture conductivity sand shale fracturing one kind of gas composition, comprises the following steps: a, the flow simulation by means of a visible proppant fracture network, simulated shale sand fracturing composition slickwater grit transport processes within the fracture, obtaining combinations of different experimental conditions of grit sand fracturing video transport; B, by using the gradation processing method and the spot scanning method, obtaining different size grit proppant distribution curve, using to obtain a linear regression of different proppant particle grit distribution shape function; C, according to API infusion chamber dimensions, using the principle of geometrical similarity established API diversion chamber grit distribution shape function, and the corresponding shape of the proppant-laid, implemented as a combination evaluation sand fracturing fracture conductivity. This method can be easily and accurately achieve a combination of shale gas Sand Fracturing quantitative evaluation of fracture conductivity, provide experimental support for the optimal combination of sand fracturing design, improved shale fracture conductivity.


This paper proposes a novel LSTM model for precise prediction of initial register value in OLED Gamma tuning. Usually the bottleneck of Gamma tuning speed depends on the accuracy of initial register value prediction in IC modules for each bind point. By utilizing the long short‐term memory character of LSTM, high prediction accuracy is achieved which greatly shrink the search time for register value, thus reducing the overall average tuning time for each bind point of OLED screens and enhancing the amounts of adjusted screens per unit time in autonomous pipelines.


The paper analyses the application of semantic configuration modification methods,and it focus on several major ones.The paper tends to advocate that various semantic configuration modification are popular in Tang poems except for semantic configuration modification on hyperonymy and hyponym,especially in dual and linking verses.Each method lays stress on different aspects,on one hand,it highlights signification functions such as complementation,emphasize,contrast,addition,on the other hand it includes others contextual functions such as variation and cohesion.