WHII.~. vo~ rHsToR,ar~s of science Marin Mersenne is the great correspondent, the "one man scientific journal," for historians of philosophy hc has appeared as an epistemologist. The two important studies of Mersenne in this latter guise are Robert I.enoble's Mer.wnne ou la nai.~sance du mi'canisme (1943),' and Richard H. Popkin's chapters in his The llistory ~ Scepticsm from Erasmus to Spinoza (revised edition 1979)/ For Lenoble, Mersenne is the prototypical modern scientist, rejecting essentialism and establishing a science based on the mathematical coordination of sense perceptions and operational, quantitative predictions. This new vision of science, says Lcnoble, inwflves a radically new regrounding of knowledge, exemplitied in such works as Que.stions inouyes (1634)? which arc compared to the Discour.w on Method? Popkin's view of Mersenne's epistemology differs little fi'om Lenoble's, although he connects its genesis more closely with particular cultural and political conditions in France in the 162os. l,enoblc argues that Mersenne, being primarily concerned with refuting naturalistic and magical doctrines, wished to maintain the concept of perfectly regular natural law as a means of retaining the interpretation of Biblical miracles as genuine cases of divine intervention. Since Mersenne (for


In this paper, the localization of Terrestrial Trunked Radio (TETRA) terminals has been exploited to enable advanced management strategies in emergency events. The location awareness of the available handheld and vehicular terminals in the monitored territory is fundamental for a centralized supervision and control. In this context, the proposed system architecture extends the potentialities of the TETRA technology supporting the interactions between the control center and the end users with a mobile App installed on tablet platforms. A set of advanced functionalities have been implemented to optimize and support through user-friendly interfaces the most frequent procedures of operational units. The system has been experimentally tested on the TETRA network of the Autonomous Province of Trento, Trentino, Italy, and is under testing by the main officers of the local operational units.


How the turbulent energy cascade develops below the magnetohydrodynamic scales in space and astrophysical plasmas is a major open question. Here, we measure the power spectrum of magnetic fluctuations in Parker Solar Probe's observations close to the Sun and in state-of-the-art numerical simulations of plasma turbulence. Both reveal a power-law behavior with a slope compatible with $-11/3$ at scales smaller than the ion characteristic scales, steeper than what is typically observed in the solar wind and in the Earth's magnetosheath. We explain such behavior by developing a simple two-fluid model which does not require any kinetic processes nor electron-inertia effects. This is characterized by a significant contribution of the ion kinetic energy to the total turbulent energy cascade at sub-ion scales, although the dynamics is driven by the magnetic field through the current density. We expect that this regime may be relevant for a broad class of low-beta plasmas, e.g. the solar corona, non-relativistic magnetized jets and disks, and laboratory plasmas.


AbstractWhen the Swedish Centre Party, Centerpartiet, just before Christmas 2012 released a draft for new program of ideas a powerful "winter storm" broke out. Ideas that Centerpartiet would abolis ...


236-10-010 Authority. [Order 76-5, § 236-10-010, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-015 Impact of guidelines on the department. [Order 76-5, § 236-10-015, filed 5/14/76.] Repealed by WSR 98-01116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-020 Scope and coverage of this chapter. [Order 76-5, § 23610-020, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-030 Adoption by reference. [Order 76-5, § 236-10-030, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-040 Integration of SEPA procedures with other governmental operations. [Order 76-6, § 236-10-040, filed 8/31/76; Order 76-5, § 236-10-040, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-050 Timing of the EIS process. [Order 76-6, § 236-10-050, filed 8/31/76; Order 76-5, § 236-10-050, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-060 Summary of information which may be required of a private applicant. [Order 76-6, § 236-10-060, filed 8/31/76; Order 76-5, § 236-10-060, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-070 Sensitive areas. [Order 76-5, § 236-10-070, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-080 Preparation of EIS by persons outside the lead agency. [Order 76-5, § 236-10-080, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-090 Designation of responsible official. [Order 76-5, § 23610-090, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-100 SEPA public information center. [Order 76-5, § 236-10100, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120. 236-10-110 Severability. [Order 76-5, § 236-10-110, filed 5/14/76.] Repealed by WSR 98-01-116, filed 12/18/97, effective 1/18/98. Statutory Authority: RCW 43.21C.120.


The aim of this review is to describe some of the main cell adhesion molecules in animals and plants in a simple and easy-to-read format and then, where possible, make comparisons to highlight common themes. A recent review by Baluska et al. (2003) compared signalling aspects of many of these molecules, while this review will concentrate on cell adhesion processes. All multicellular organisms have some form of extracellular matrix (ECM). Animal tissues vary enormously in the amount of ECM they contain. Connective tissue is particularly rich in ECM, and the individual cells within connective tissue may not be in close contact. Epithelial tissue, in contrast, has minimal ECM, and the individual cells of epithelial tissue are in very close contact and exhibit strong cell— cell adhesion. All plant tissues are normally associated with an extensive ECM, termed the cell wall. However, the nature of this wall differs between plant species, and within the tissues of an individual plant. In both plants and animals, the ECM is structurally complex. Its architecture is, however, always remarkably similar, consisting of a rigid framework embedded in a gel-like matrix, a composition not unlike that found in many fibre-composites such as fibre glass. In animals, the ECM is generally composed of glycoaminoglycans


Bertalan Arkay's church in Budapest-Varosmajor is the advent of modern Hungarian church architecture. He designed several churches after 1945, which are far less known or their evaluation is somewhat one-sided. This paper discusses the building history and surviving plan documentation of two of the fifteen churches built between 1945 and 1970. These churches are known to some extent from special literature. To learn the building history of the churches of Hort and Taksony I studied the documents of the parishes and the State Office for Church Affairs, as well as the relevant articles in the ecclesiastic media of the time. I examined the Arkay estate in the Architectural Collection of the Kiscell Museum of the Budapest History Museum to find the plans. 27 plans of the Hort church – of them 11 of the furnishing – and 35 of Taksony (only the building) survive. The historical inquiry reveals that while literature on ecclesiastic art registers both churches, art history only keeps tabs on the Taksony church. E...


Background: In light of recent shifts away from fee-for-service and toward alternative payment models (APM), national trends in quality performance for common cardiac conditions, such as CAD, are i...


SummaryBupropion (BUP) is a new, monocyclic, second-generation antide-pressant with efficacy comparable with that of the tricyclics but possessing a more favorable side-effect profile. Therapeutic drug monitoring services are expected to be widely available following the marketing of BUP, yet relati


In the days when flammable anesthetic agents, electrosurgical unit, and laser were frequently used, fire in the operating room became special. When the fire occur, the patients are in the status of anesthesia with their actions restricted . So the injure to them will be very serious. Therefore, it is incumbent upon all those who work in the operating room to be aware of how to prevent fires and what to do if one should occur. Operating room fires can be classified into two types: those that occur in the patient and those that occur on the patient. Fires that occur in the patient would include airway fires such as by ignition of an endotracheal tube or a fiberoptic bronchoscope or intra - abdominal fires. Fires occurring on the patient include ignition of drapes or surface fires that are fueled by supplemental oxygen. This paper presents some speciality and preventive actions of fire in the patient and on the patient .


The single beam Asterix IV high power iodine laser ((lambda) equals 1.32 micrometers ) provides at present a maximum output energy of 2.1 kJ at a pulse length of 5 ns and an output power of 4 TW at 0.3 ns pulses. This laser is designed to deliver pulses with lengths ranging from 0.2 to 5 ns with a maximum power of 5 TW and an energy of up to 2 kJ. Asterix IV has been developed on the 10 years experience with the 1 TW Asterix III laser and with the support of a 1D and a 3D pulse propagation code. Special emphasis has been put on achieving a high overall system efficiency and laser beam intensity profile as homogeneous as possible. In this paper the measures for optimizing the laser performance and the results obtained will be described.


It is inevitable for cloud droplets to suffer from inherent contamination. This comes from the mechanism of cloud droplet formation. Almost all cloud droplets are formed by heterogeneous nucleation, i. e., by condensation of the atmospheric water vapour onto hygroscopic aerosol particles as (NH4)2SO4 called cloud condensation nuclei (CCN). Homogeneous nucleation (without CCN) requires water vapour supersaturation as unreally high as several hundred percent. During cloud droplet formation, (NH4)2SO4 dissolves to break up into ions in condensed water. These ions are impurities in pure condensed water and they bring about inherent contamination in the cloud droplets. Therefore, cloud droplets are congenitally never pure, even if they do not suffer from any acquired contamination by scavenging of the atmospheric pollutants. In order to estimate the inherent pollution of new-born cloud droplets onto (NH4)2SO4, the most abundant CCN, a mathematical model of inherent contamination has been constructed, based on both the chemical equilibrium in cloud droplet and the competitive growth of multiple cloud droplets. Calculations show that the higher the CCN number density, the more the cloud droplets are contaminated and that inherent contamination acidifies cloud droplets more than atmospheric CO2, does.


Background: Chronic Spontaneous Urticaria (CSU) is a common health problem and
its clear etiology is not established yet. Several theories have been tried to illustrate its
etiology and pathogenesis. Autoantibodies and inflammatory cytokines like IL-23 and IL17 are hypothesized to take part in CSU pathogenesis and outcome. Objectives: To
detect serum levels of IL-23 and IL-17A among CSU patients and to determine its
correlation with disease severity and its relation to autoreactivity. Methodology: Serum
levels of IL-23 and IL-17A were measured in 23 patients with CSU (CSU group) and 23
healthy controls (control group). In CSU group, Weekly Urticaria Activity Score (UAS7)
was recorded to assess disease severity. Autologous Serum Skin Test (ASST) was
performed to assess autoreactivity. CSU patients᾿ group was subdivided, based on ASST,
into positive ASST (ASST+
) and negative ASST (ASST-
) subgroups. Correlation of serum
IL-23 & IL-17A levels, with UAS7 and ASST response were analyzed. Results: CSU
group had higher serum IL-17A and IL-23 levels than control group (P=0.000). ASST+
CSU had higher serum IL-17A and IL-23 levels than ASSTones (P=0.000). Additionally,
UAS7 was higher in ASST+ subgroup than ASST- subgroup (32+11.7 versus 16.27+
9.92; P =0.005). There was significant positive correlation between disease severity and
serum levels of both IL-17A and IL-23 among CSU patients (r= 0.626 & P= 0.001 and
r=0.515 & P= .012, respectively). Conclusion: Increased serum IL-17A and IL-23 levels
may constitute two major determinants of CSU pathogenesis and severity.


The energy dispersive X-ray Fluorescence (EDXRF) system (Shimadzu EDX-720 spectrometer) was applied to investigate the metal contents in mineral-ore samples from different mines: Hermyingyi, Wagone, Kalonta, Heinda and Kanbauk in Dawei district (Tanintharyi region). According to results, it was found that the mineral-ore samples of interest were mainly based on tungsten or wolfram (W), tin (Sn), manganese (Mn) and iron (Fe) metal elements. In addition, some of these samples were composed of other combined metal elements: Pb, Nb, Mo, Ti, Ac, Zr, Bi, Ni, Th, Au and Cr, respectively. Gold mineral (Au) element was observed obviously only in the sample M (3) from Kalonta Mine but not found in elsewhere.


The institution of higher education is the base that brings up high-quality and innovative talents,this text combines the vehicle project speciality closely,study the training mode of university student's scientific and technological innovation ability,point out that should form the scientific education idea,establish the correct view of quality of education,advance quality-oriented education actively;Use the scientific teaching way,adhere to people first,train students' scientific spirit and ability of practice actively;Construct and build the academic scientific and technical innovation activity platform after class taking training university student's scientific and technological innovation ability as goal actively,strengthen the construction of every system of promoting to train university student's scientific and technological innovation ability.


Part of Pearl River within the boundaries of Yunnan Province is the important industrial and agricultural economic zone of the province.Regional total output value of the area and industrial added value separately occupied 30.1%,42.7% of the total value of the entire province,respectively,which were as 1.5 times as the entire province level as well as capita GDP.The water supply structure based mainly on water storage projects and other secondary diverting and lifting water projects had basically formed,but the average of water resources was only 2 221 m3 per capita.Water quality of present Nanpan River and partial section of the main branch of river was V category of water body,environmental quality of the high land moor water is unoptimistic.Taking MIKE BASIN as the technology platform,and by saving,protecting and highly effectively using water resources,we carried out researches on the supply and demand of water predictions and rational allocation,and we carried on discussions on the main problems of effects on taking advantage of water resources continually,such as saving water resources,dealing with accidental pollution events,the climatic change and the extreme climate event,establishing the rivers ecology compensation mechanism and so on.


This essay studies the rhetorical situation of the crowdfunding site Patreon.com, with a particular focus on the construction of ethos. Taking off from the conception of ethos as a discursive dwell ...


Embryo transfer (ET) is a procedure that involves the recovery of embryos from the reproductive tract of genetically superior donor females and the transfer of these embryos into the uterus of recipient females for the birth of live offspring. This technology has numerous important applications in farm animal production, including genetic improvement and the national and international movement of genetic material (i.e., embryos) with minimal risk of disease transmission, reduced transportation costs, and no effect on animal welfare compared with the transport of live animals. In addition, ET is fundamental for other biotechnologies related to the in vitro production and manipulation of embryos. Despite these important applications, the commercial use of ET widely varies among species. While ET has been extensively used for commercial purposes in cattle for more than 30 years, its use in ovine, caprine, and particularly porcine species is currently very limited or nonexistent in contrast to other biotechnologies (Rodriguez-Martinez, 2007). One of the most important factors in the ability to exploit ET technology at a commercial level is the ability to collect the embryos from the donors and to transfer them to the recipients using procedures that can be easily performed under field conditions. As stated by Betteridge (2006), "the simpler the technique, the wider its applicability." A clear example of this statement is the evolution of ET in cattle, which has been excellently reviewed by Betteridge (2003). In the 1950s, the first efforts to transfer embryos into the uterus of a recipient with a non-surgical procedure were ineffective (Lamming and Rowson, 1952). At that time, surgical methods for embryo collection and transfer in cows were well developed. However, ET did not grow in popularity until non-surgical methods were developed. By the 1960s, the first calf born using non-surgical ET was obtained (Mutter et al., 1964), and new methods of depositing embryos using non-surgical procedures were reported (Rowson and Moor, 1966). During the 1970s, non-surgical methods for collection and transfer completely replaced surgical methods, and the procedures were improved with the development of different non-surgical catheters and protocols. These investigations resulted in a non-surgical, practical procedure for ET in cattle, leading to an explosive increase of commercial ET, today a booming worldwide business. Currently, ET of in vivo (or in vitro) produced embryos to the uterus of a recipient cow is easy and reliably performed by transcervical intrauterine deposition, with > 60% of pregnancy rates (reviewed in RodriguezMartinez, 2012). A major factor contributing to this development was the practical necessity of avoiding surgery if ET was to become practicable in the field. Necessity really was the mother of invention (Betteridge, 2003). At least 100,000 donor females were flushed in 2010, with more than 730,000 embryos collected and almost 600,000 embryos transferred, 55% of which were frozen. In contrast, the number of sheep and goat embryos collected in that year was less than 5% and 0.1%, respectively, of that recorded for cattle. Unfortunately, no swine ET activity was reported by any country in 2010, although the numbers of flushings reported for 2008 and 2009 in the US were 134 and 9, respectively. In addition to commercial and market factors, current ET in small ruminant and pigs are performed Design, development, and application of a non-surgical deep uterine embryo transfer technique in pigs


This work presents a study of the frequency dispersion effects of the capacitance-voltage characteristics of organic PMMA on P3HT Thin Film Transistors (TFT) using simulated curves. For validation, simulated CV characteristics at 1 MHz are compared with experimental curves, measured at the same frequency.


Methods of detecting proximity between a mobile terminal and a wireless accessory device having an associated support function for use with the mobile terminal include establishing a wireless communication connection between the wireless accessory device and the mobile terminal. The established wireless communication connection is utilized to provide the associated support function. In addition, a wireless signal having a limited range is communicated between the mobile terminal and the wireless accessory device. The wireless signal indicates a proximity between the mobile terminal and the wireless accessory device. An alert signal indicating that the proximity between the mobile terminal and the wireless accessory device has exceeded a predetermined range is provided responsive to the communicated wireless signal when the established wireless communication connection is not being utilized to provide the associated support function. Related devices are also provided.


W here am I? Routed into the Westfield Shopping Centre in Stratford, East London I'm trying to get to the Queen Elizabeth Park (Figure 1). Signposts out seem to have disappeared; I've been sucked into a zone of full-intensity shopping. It is September 2014—exactly two years since the last of the London Olympics jamboree left town with the Paralympic Games closing ceremony—and my first visit back since sitting high up in the Aquatics Centre amidst a flurry of Union Jacks. I find a route out through the multi-storey car park and emerge into the Park via billboards proclaiming a forthcoming 'International Quarter'. There's a businessman in a striped suit, a group of headscarfed young women, cyclists, people photographing reeds, swarms of seagulls, underworked kiosk vendors. There's smartly uniformed security people on bikes, police on bikes, there's cleaners patrolling in fluorescent jackets with the Park logo, there's gardeners tending vegetation which manages not to leave any hidden spaces. I sit down and notice a continuous rumble of construction activity, and how in the distance to the west the towers of central London lurk in the late-summer haze. I take out The Art of Dissent book. Although published in June 2012, this seems a world away; like the Stephen Gill photographs on its front and back cover, the book feels like it's been degraded. The Art of Dissent, edited by the anthropologist and sociologist Isaac Marrero-Guillamón and artist and scenographer Hilary Powell, captures a whirl of critical energy that amassed around the frustrations, anger and despair felt at the Olympic takeover of this chunk of East London. It expertly compiles 60 contributions that document an important moment in London's recent cultural energies, described as 'words that were not meant to be heard, images that were not supposed to be seen' (8). It's a rapid-fire array of short essays, photographs, poetry, artworks and speculations; produced by an assemble of artists, photographers, architectural historians, musicians, sociologists, film-makers, activists, writers and many others. No chapter outstays its welcome; no section goes without any illustrations, while a 'long poem' by Jude Rogers is split into three fragments. The book has a clear structure and direction throughout in its division into four thematic sections: 'Incursions', 'Excursions', 'Displacements' and 'Aftermaths', with the rationale for each carefully outlined in the introduction. The footnotes are squirrelled away like pylons from the Olympic Site; while the writing is always accessible even in its occasional theoretical forays into Agamben, Lefebvre and Deleuze. The book's publishers Marshgate Press, printers Calverts Co-operative and designers See Studio, deserve laurel wreaths


This paper brings to light the detail analysis of the prevalence of corruption in the Health Care Services in the slum areas of Karachi. The empirical results provide significant evidence that the residences of slum areas of Karachi in all the five districts are forced to pay bribes in order to get the basic health care facilities. However, the people living in the District Malir and District East are more exposed to corruption as compared to the other districts. Health is one of the most essential basic needs of every individual living in any society. The result shows that people with better income and education understands the importance of good health and are thus ready to pay bribes to get the health services. Moreover, in the public health care units all staff including doctors, nurses and others are actively involved in corrupt activities. KEYWORD: Petty Corruption, Health Care Services, Slum Areas


US foreign policy and the Iran hostage crisis [electronic book] , US foreign policy and the Iran hostage crisis [electronic book] , کتابخانه دانشگاه امام صادق(ع)


This book ranges more widely than its title implies, including sections on somatisation disorder, factitious disorder, and malingering. Indeed, much the same territory as covered by Somatisation , also edited by Christopher Bass and published in 1992. A comparison of the two multi-authored compilations provides a fair indication of progress …


Soil is an important and complex part of our environment. The agro-ecosystem is made up of many interacting components with multiple goals. Soil quality is one important part of sustainable agro-ecosystem management, analogous to water and air quality. Assessing soil quality may help managers identify practices that could be adapted to become more sustainable. Soil quality is the ability of a soil to perform functions that are essential to people and the environment. Soil quality is not limited to agricultural soils, although most soil quality work has been done in agricultural systems. Soil quality definitions emphasize several features. Dynamic properties include organic matter, soil structure, infiltration rate, bulk density, and water and nutrient holding capacity. Changes in dynamic properties depend both on land management practices and the inherent properties of the soil. Here, the author has presented for intrinsic and vigorous properties, soil structures and macrophores, soil quality management, etc.


Arginine through a NO mediated mechanism improves insulin resistance in type 2 diabetes. To asses the effect of a short‐term (1 week) dietary arginine supplementation on insulin resistance in glucose intolerant obese adolescents, we conducted a randomized, cross‐over study in 12 subjects (16±1 yr.;BMI 36±5 kg/m2) receiving a one week diet period of a weight maintaining protein and energy intake, or an isocaloric arginine supplemented (21 gram/day) isonitrogenous diet. At the end of each diet period they received a primed, constant, 7 hr. tracer infusion of [1‐13C]Glucose, L‐[2H3]Leucine and [2H5]Glycerol. During the last 3 hours a hyperinsulinemic euglycemic clamp (HEC; 40 mU·m−2·min−1 insulin) was conducted. Arginine supplementation improved (p<0.05) insulin sensitivity from 0.3±0.2 to. 0.4±0.2 μmol ·kg−1 ·min−1/μU/mL. There was a trend towards improvement of non‐oxidative glucose disposal (3.5±3 vs. 4.5±2 mg.kg−1.min−1; p=0.06). However, there was no effect on endogenous glucose production (‐1.0±1 vs. ‐1.0±2 mg.kg−1.min−1; p=0.99). Arginine had no effect on protein breakdown or lipolysis. A one week oral arginine supplementation (21 gr/day) in obese adolescents improves insulin resistance.


We report the effects of K:D-Rib, a D-ribose and KHCO3 water solution on HTB-126 human cancer cell line proliferation and the preliminary ultraviolet-visible (UV-VIS) measures of DNAzyme as biosensor of extracellular K+ concentration. On the one hand, we demonstrate that the synergic action of KHCO3 and D-ribose from one side has a cytostatic effect on human breast cancer cell line increasing by 30% the doubling population time of treated cells with respect to the control; and on the other hand we demonstrate how it seems to permit the K+ uptake.


A scientific relationship among self, society and nation is still not clearly known in philosophy, sociology and economics because of lack of concrete historical human data that would enable to substantiate it. Humanity experienced many conflicting economic and political systems and countless wars. In addition, there have been major different religions in societies and nations. Consequently, philosophers, sociologists and economists have bee investigating to study the scientific relationship among self, society and nation. The author (Chung, 2009; 2012b) proposed a theory of the science of self, mind and body. Further, he presented a desirable ideology based on the perspective of his theory: the "communal freedom democracy". In this study, he compared the ideology of the "communal freedom democracy" and the "surviving capitalism" of Ringmar (2005). A considerable agreement is present between characteristics of the "communal freedom democracy" and the" surviving capitalism". The scientific relationship among self, society and nation is presented in this study.


Fpg is a DNA glycosylase that recognizes and excises the mutagenic 8-oxoguanine (8-oxoG) and the potentially lethal formamidopyrimidic residues (Fapy). Fpg is also associated with an AP lyase activity which successively cleaves the abasic (AP) site at the 3′ and 5′ sides by βδ-elimination. Here, we present the high-resolution crystal structures of the wild-type and the P1G defective mutant of Fpg from Lactococcus lactis bound to 14mer DNA duplexes containing either a tetrahydrofuran (THF) or 1,3-propanediol (Pr) AP site analogues. Structures show that THF is less extrahelical than Pr and its backbone C5′–C4′–C3′ diverges significantly from those of Pr, rAP, 8-oxodG and FapydG. Clearly, the heterocyclic oxygen of THF is pushed back by the carboxylate of the strictly conserved E2 residue. We can propose that the ring-opened form of the damaged deoxyribose is the structure active form of the sugar for Fpg catalysis process. Both structural and functional data suggest that the first step of catalysis mediated by Fpg involves the expulsion of the O4′ leaving group facilitated by general acid catalysis (involving E2), rather than the immediate cleavage of the N-glycosic bond of the damaged nucleoside.


The problems of formation of neutron fields are using the radionuclide neutron sources. Theoretical estimates of the contribution to the values of the neutron flux density, kerma and ambient dose equivalent scattered neutron radiation under various conditions of use of neutron sources. The coefficients for calculating the values of different variables at different distances from the source are using the measured values at certain distances from the source. The values of the average energies for neutron spectra are obtained using the radionuclide neutron sources.


We propose a new mechanism for high-pitch perception by a system of multiple neurons capable of resolving frequencies higher than the frequency associated with the mean refractory period up to a multiple thereof.


The invention belongs to the technical field of the application of photoelectricity products, and particularly relates to an image and information fusion display method for a high-definition video. In the prior art, a video and information fusion display method is poor in video compression effect and poor in instantaneity, and multi-element information display is difficult to achieve. According to the image and information fusion display method for the high-definition video, through the steps of acquiring and transmitting high-definition images, acquiring YUV data, carrying out electronic image stabilization and image enhancement, carrying out multi-element information fusion display and the like, intelligentized monitoring effects are displayed before a user accurately, clearly and smoothly, and good instantaneity is achieved while video compression effects are ensured. Meanwhile, detected target information, own ship location information and the like are superposed on the high-definition video by combing a radar, a turntable, a GPS, a compass and the like, the multi-element information display is achieved, the operating difficulty of a system is reduced, the operating and judging time of staff is reduced, and the working efficiency of the system is improved.


The pH and oxidation-reduction (redox) potential of surface waters and sediments are important to the regulatory processes affecting the solubility of heavy metals and their distribution among various geochemical forms. Changes in pH or redox potential of a sediment water system can result in chemical transformations of metals between geochemical forms affecting their availability to aquatic and benthic organisms. These parameters may also influence the uptake of heavy metals by plants grown on dredged materials applied to land. A moderately low pH and reducing redox potential environment generally favor the relatively bioavailable soluble and exchangeable chemical forms of metals. Sparingly soluble metal oxides and hydroxides predominate at higher pH and oxidation levels. Important regulatory mechanisms affecting the chemistry of heavy metals include precipitation as insoluble sulfides under highly reduced conditions, formation of discrete metal oxides of low solubility or adsorption to colloidal hydrous oxides in aerobic, neutral or alkaline environments, and complexation with soluble and insoluble organic matter at all levels of pH and redox potential. Conversely, complexation with insoluble organics is an important sink for many metals. Redox potential influences both of these processes by quantitatively and qualitatively affecting the organic compounds present. Reduced environments favor slower degradation ofmore » organics and the formation of structurally complex, large molecular weight molecules which are more effective in binding metals. This report deals with the influence of pH, redox potential, and sediment properties on the chemistry of selected metals in sediment-water systems. Also, data indicating the influence of pH and redox potential on heavy metal uptake by plants grown on sediment material will be discussed.« less


Purpose: To determine if breath coaching to maintain a consistent breathing amplitude at expiration is feasible in a clinical setting. Method and Materials: This technique consists of two phases of observation and active breathing to restrict the end‐expiratory phase so as to never exceed the lower limit of the gate. The first phase consists of 2 minutes of observation followed by 3 minutes of active breathing using visual feedback, while the second phase consists of 2 minutes of observation followed by 8 minutes of active breathing again using visual feedback. The purpose of the 2‐minute observation periods is to set the end‐expiratory gate at a comfortable level for the patient. Following the first phase the patient assesses whether the lower limit of the gate is appropriate and if it can be maintained in a reproducible manner for an extended period without exhaling below the gate. We have studied ten healthy volunteers of varying ages. The RPM system (Varian) was used to monitor the respiratory cycles of the volunteers. The volunteers self‐monitored their respiration via goggles that were turned on following each 2‐minute observation period. Results: The visual feedback was the key factor to reproducibly maintain the end‐expiratory gate. We were able to determine that all subjects were successful in sustaining their breathing pattern such that they did not exceed the lower limit of the gate and they were all able to do so comfortably. Only one volunteer would have needed to have the gate shifted upwards for actual treatment delivery. Only one volunteer would have needed to have the gate shifted upwards for actual treatment delivery. Conclusion: Breath coaching to maintain a consistent expiratory amplitude is feasible. It should not place a heavy burden on the patient during respiratory‐gated radiotherapy.


The article addresses the issue of the ineffectiveness of norms of international humanitarian law during modern armed conflicts, the content of certain norms of the Geneva Conventions with the aim of improving the international legal regulation of the status of victims of armed conflicts. An analysis of international legal acts and national acts adopted in Ukraine after the introduction of martial law in Ukraine, which are aimed at improving the status of victims of the armed conflict, has been carried out. Attention is drawn to the fact that the russian-Ukrainian war qualifies as an international armed conflict, in which, in accordance with the norms of international humanitarian law, the combatants are given the status of prisoners of war. At the same time, russia grants them the status of "persons opposing a special military operation" without guaranteeing the protection of the rights of prisoners of war, does not distinguish the status of civilians in an armed conflict, which is a significant violation of the norms of international humanitarian law. It is proposed to adopt the conventional norms of international humanitarian law in terms of regulating the exchange of prisoners of war.Different definitions that denote certain vulnerable categories of the civilian population during an armed conflict are analyzed in relation to the definition of "indirect victims of an armed conflict". Proposals for the creation of a coordinating body that would take care of the issues of indirect victims of the armed conflict, the development of an effective compensation mechanism for destroyed or damaged property during armed aggression, and the determination of the legal status of persons who have been deprived of personal freedom as a result of armed aggression against Ukraine are supported. Today, international and national legislation is clear on the appointment - who should be taken into account by the persons who suffered in the wake of the violent aggression. It is concluded that the norms of international humanitarian law need to be updated and revised for their future observance and implementation by all subjects of international law.


Although a photoelectrochemical approach offers one of the most promising processes for solar energy conversion, it still suffers from the unavailability of photocatalysts that can absorb the photons across the ultraviolet–visible region and efficiently generate electron–hole pairs with longer lifetimes. Here, we report the fabrication of heterostructure comprising reduced TiO2 (TiOx) and reduced graphene oxide (RGO) through a facile nonhydrolytic route using benzyl alcohol as a solvent, shape-directing, and a strong reducing agent. Reduction of Ti4+ and graphene oxide was observed in the absence of any additional reducing agent. Nearly monoshaped square nanoplates of TiOx with size in the range of 10–20 nm were formed. Nanoplates consisted of Ti3+ and were capable of absorbing a broad solar spectrum (ultraviolet–visible region). Formation of Ti3+ was confirmed by electron paramagnetic resonance spectroscopy, while a Mott–Schottky plot corroborated the band shift in TiOx. Findings suggest that defects wer...


Environmental Microcatastrophes Cancer as a Catastrophe in Organisms Life and Atmosphere Technosphere-Biosphere Interaction and Global Climate Dynamics of Atmospheric Ozone Closed Ecological Systems and Earth's Biosphere Environmental Damage Fining and Environment Market Marketing Dynamics Labor Market and Capitalism Unemployment Dynamics Objects of Nature as Commodities Long-Term Motivation Democracy in the Light of Electoral Procedures.


The ability to obtain single cell transcriptomes for stable cell types and dynamic cell states is ushering in a new era for biology. We created the Tabula Drosophilae, a single cell atlas of the adult fruit fly which includes 580k cells from 15 individually dissected sexed tissues as well as the entire head and body. Over 100 researchers from the fly community contributed annotations to >250 distinct cell types across all tissues. We provide an in-depth analysis of cell type-related gene signatures and transcription factor markers, as well as sexual dimorphism, across the whole animal. Analysis of common cell types that are shared between tissues, such as blood and muscle cells, allowed the discovery of rare cell types and tissue-specific subtypes. This atlas provides a valuable resource for the entire Drosophila community and serves as a comprehensive reference to study genetic perturbations and disease models at single cell resolution.


Objective: Revealing microfibrillar-associated protein 4 (MFAP4)'s function and its clinical significance in hepatocellular carcinoma (HCC). Methods: Quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting were used to evaluate MFAP4 mRNA and protein expression in paired HCC and paracarcinoma tissues, respectively. MFAP4 serum concentration was detected using enzyme-linked immunosorbent assays in healthy people (n = 30), cirrhosis (n = 15) and HCC patients (n = 80). MFAP4 protein expression was detected in two tissue microarrays (n = 60 and n = 90). Plasmids were transfected into human HCC cell line Bel-7402, and MFAP4 function was determined in vitro in cell experiments. Furthermore, tumorigenicity studies in nude mice served to assess the function of MFAP4 for HCC. Results: Both MFAP4 mRNA and protein expression were significantly downregulated in HCC tissue compared with paracarcinoma tissue (P < 0.05). Decreased MFAP4 expression in paracarcinoma tissue was associated with poor postoperative survival in HCC patients (P = 0.027). MFAP4 was also downregulated in HCC sera compared with healthy people (P < 0.05). In vitro, MFAP4 upregulation in Bel-7402 cells induced S phase arrest, promoted apoptosis, and inhibited migration and invasion. Western blotting indicated MFAP4 overexpression increased CDK4, CDK6, pRB, P27, and BCL-XS expression. Tumorigenicity study showed that the upregulation of MFAP4 inhibited the proliferation of Bel-7402 cells in nude mice. Conclusions: MFAP4 expression was significantly lower both in sera and tissue of HCC patients. MFAP4 can serve as molecular marker for HCC diagnosis and prognosis. Additionally, MFAP4 acted as an important HCC tumor suppressor by inducing S phase arrest, and promoting apoptosis, cell migration, and invasion.


To make the use of resources in the construction process of offshore equipment project more balanced,a mode of resource leveling for offshore equipment multi-project is established,and a solution based on immune genetic algorithm(IGA)is proposed.The principle of biological immune system is adopted to improve the genetic algorithm.To overcome the defects of genetic algorithm easy to fall into the local optimal solution,the groups update strategy based on antibody concentration to maintain antibody population diversity,and according to the heuristic information of the model,the constraints were divided into two different types,and treated respectively.Finally,an example is given to validate the feasibility and effectiveness of the approach.


Martin Luther King's speech I Have a Dream expresses his dream of longing for democracy,freedom,racial equality and integration in his speech.The speech is poetic and charming.The paper uses Halliday's transitivity theories to analyze the different types of transitivity processes by the statistical data of the author's choice of transitivity processes,and elaborates on the stylistic effect of transitivity features in expressing the author's real intention and the theme of the speech,which denotes the high frequency of transitivity processes is a choice by which the author expresses his real intention and the theme of the speech.


With the increasing importance of monitoring urban areas, the question arises which sensors are best suited to solve the corresponding challenges. This letter proposes novel node tests within the random forest (RF) framework, which allows them to apply them to optical RGB images, hyperspectral images, and light detection and ranging (LiDAR) data, either individually or in combination. This does not only allow to derive accurate classification results for many relevant urban classes without preprocessing or feature extraction but also provides insights into which sensor offers the most meaningful data to solve the given classification task. The achieved results on a public benchmark data set are superior to results obtained by deep learning approaches despite being based on only a fraction of training samples.


Michel Foucault has inspired a rich body of work in the field of critical social theory and the social sciences in general. Few  scholars working in the area of social movement studies, however,  have applied a  Foucauldian perspective to examining the  twin phenomena of social mobilization and collective action.  This may stem, in large part, from the commonly held assumption that Foucault had far more to say about 'regimes of power' than ever about mobilization and collective action or contention politics in general. Be that as it may, a close interrogation of his work reveals the broad contours of a theoretical framework for analyzing social movements whose chief merit lies in a sensitivity to the sociopolitical context within which oppositional movements form, develop and conduct their operations.  This paper aims at delineating what a Foucauldian model of social movements would entail, with specific reference to the Middle East and North Africa (MENA), a region traditionally consigned to the margins of social movement studies. An enquiry of this kind is important because, as I argue, the leading mainstream social movement theories that have been applied to contemporary MENA cases invariably fall short of fully elucidating the phenomenon of mass mobilization. Specifically, leading mainstream theories are prone to certain universalistic assumptions and 'West-centric' orientations that render them incapable of accounting for the specificities of MENA cases. I shall demonstrate how a Foucauldian perspective on social movements can bypass the problem of applicability to the MENA region by mapping out a theoretical framework whose chief merit lies in a sensitivity to the sociopolitical context within which oppositional movements form, develop and conduct their operations. At the same time, I argue that a Foucauldian model transcends social movement theories with their linear conception of social and political progress, their exclusivist understanding of sociopolitical 'development' and 'modernist' assumptions by advancing an account of 'multiple modernities.'


The numerical phase mismatch across FDTD lattice layers with different sets of update equations has been investigated. A predictive equation of numerical reflections across high-order/low-order layers has been derived. Based on this equation the standard Yee (S22) update equations have been modified to allow their implementation around PEC boundaries and other special situations in an otherwise global high-order implementation, while keeping spurious reflections at the hybrid interface to a practical minimum and independent of the traversing wave direction. S22 Phase matching has been developed and verified in both S24 and M24 high-order hybrid algorithms. Keywords— FDTD, Numerical Dispersion, High-Order Schemes, Phase-Matching, Electrically Large Structures.


Members of an infection control program save money by reviewing and modifying a hospital's policies and procedures in collaboration with other hospital staff members.


H-form Fe-silicate catalysts showed high activity and stability for the reduction of NO with propylene in the presence of a high concentration of oxygen. The catalytic activity of Fe-silicate was hardly affected by the presence of SO2.


We investigate the potential of mid-infrared (mid-IR) optical coherence tomography (OCT) by imaging a number of industrially applied ceramics and plastics and by imaging the same materials with a state-of-the-art near-infrared OCT system.


Restenosis after percutaneous coronary intervention (PCI) is still a clinically serious problem. We examined the treatment efficacy of IMD-0354, a novel IKK inhibitor, on arteriopathy. Using C57BL/6J mice, a wire-injury model was prepared and the mice were intraperitoneally injected with IMD-0354 or vehicle twice a day. The vehicle-treated injured arteries showed significantly thickened intima (3.77 ± 0.59, n = 8), however, IMD-0354 suppressed its progression (1.62 ± 0.22, n = 10, P < 0.05) on day 28. While enhanced expression of PCNA and NF-κB was observed in the untreated injured arteries, IMD-0354 significantly suppressed their expressions. Quantitative RT-PCR revealed that the expression of several inflammatory factors was reduced in the arteries from mice which received IMD-0354 treatment compared with the control animals. Thus, this drug may effectively prevent restenosis after coronary intervention and other cardiovascular diseases.


The classical micellization behavior of block or graft copolymers in selective solvent was briefle described and a variey of new approaches to polymer micellization caused by specific interactions(hydrogen bonding, ionic interaction, polymer metal ion coordination interaction), change of termperature and media properties and chemical reactions, etc. was reviewed. Besides, new advances in the further evolution of the micelles leading to core cross linked micelles and shell cross linked micelles are discussed.


The development of social marketing, as an important area of analysis and research, has opened up multiple opportunities for organizations to engage in society's problems. Whether we talk about non-profit organizations engaged in health or environmental programs or private companies willing to act responsibly, their goal is a common one: to help improve people's lives by promoting responsible behaviour in society. This paper aims to extend the area of research for "cause-related marketing" by highlighting the importance of partnerships between non-profit organizations and companies based on social responsibility. As a result, the article proposes and analyzes four features of social partnership: motivation, promotion, efficiency and law effect. The study examines the Romanian consumers' opinions regarding the need of collaboration between corporations and non-profit organizations for achieving common social goals. Using the structural equation model, the paper describes the relations between each of the variables considered and social partnership and measures the extent to which these variables can influence the collaboration between organizations. The article tests and then proposes a model of the considered variables. The results obtained describe the characteristics of social partnership marketing programs and their importance for the consumer.


This paper investigates the possibility of today's OECD economies entering into a very long period of poor per capita economic growth and very low real interest rates. We construct a general equilibrium model with overlapping generations of heterogeneous individuals, differing in ability and human capital, and with genetic and financial transfers from parents to children. Our model allows to study within one coherent framework the effects of those factors that are most often mentioned in the literature as possible drivers of secular stagnation: demographic change, a slowdown in the rate of technical progress, rising inequality, borrowing constraints, and downward rigidity in the real interest rate. We calibrate our model to Belgium and find that its predictions match key facts in Belgium in 1950-2009 very well. We then simulate projected future changes in technical progress and demography. In alternative scenarios we additionally impose rising inequality, borrowing constraints and/or a lower bound to the real interest rate. When we assume unchanged public policies and a modest future rate of technical progress, our conclusions about future per capita output and growth are rather pessimistic. Demographic change is by far the most influential cause of low growth. If a lower bound to the real interest rate is binding, it could considerably aggravate the problem of stagnation.


Received: December 29, 2016 Revised: March 03, 2017 Accepted: March 09, 2017 Abstract: Background: Anaesthetics are widely used in new-borns and preterm infants, although it is known that they may adversely affect the developing brain. Objective: We assessed the impact of the volatile anaesthetic, isoflurane, and the intravenous analgesic, fentanyl, on immature and mature embryonic neuronal cells. Methods: Primary neuronal cultures from embryonic rats (E18) cultured for 5 (immature) or 15 days (mature) in vitro (DIV), respectively, were exposed to isoflurane (1.5 Vol.%) or fentanyl (0.8 200 ng/ml) for 24 hours. Experiments were repeated in the presence of the γamino butyric acid-A (GABAA) receptor antagonists, bicuculline or picrotoxin (0.1 mmol/l), or the pancaspase inhibitor zVAD-fmk (20 nmol/l). Cell viability was assessed by methyltetrazolium (MTT) metabolism or lactate dehydrogenase (LDH) release. Results: Isoflurane reduced cell viability significantly in primary neuronal cells cultured for 5 DIV (Δ MTT -28 ±13%, Δ LDH +143 ±15%). Incubation with bicuculline, picrotoxin or zVAD-fmk protected the cells mostly from isoflurane toxicity. After 15 DIV, cell viability was not reduced by isoflurane. Viability of primary neurons cultured for 5 DIV did not change with fentanyl over the wide range of concentrations tested. Conclusion: Immature primary neurons may undergo apoptosis following exposure to isoflurane but are unaffected by fentanyl. Mature primary neurons were not affected by isoflurane exposure.


Summary From a series of alkyl-pseudothioureas studied, 10-undecen-1-yl-thiopseudourea iodide (AHR-1911) was selected as antifungal-antibacterial agent for topical use. The preparation possesses in vitro and in the local infection of mice an anti-infective activity on the order of the antibiotics. This activity is associated with a considerable antiphlogistic action demonstrated in experimental arthritis of various types and in burns induced on rat skin.


This paper explores the relationship between art and morality from British philosopher and novelist Iris Murdoch's dis- tinctive approach to ethics. Murdoch defends the close connection between art and morality, beauty and goodness, and aesthetics and ethics by focusing on the role of art in moral life, and in particu- lar on the analogy between the aesthetic experience in creating and enjoying art and the moral experience. The paper elaborates on Mur- doch's argument for the vital and intrinsic connection between art and morality in terms of two main themes. First, art reveals the real- ity of the human condition and in turn enhances our moral percep- tion of what is real and cultivates the virtue of loving attention to others. In this light, art and morality are one in that the essence of both is love, which is the true vision of individuals. Second, in culti- vating the true vision, art does not simply serve as an aid for morality, but is a spiritual exercise in purifying our psychic energy by redirect- ing our attention in the search for the good. This assertion leads to the second level of inquiry of this paper, which examines Murdoch's thesis of salvation through art in the modern secular world.


SUMMARY General estimating equations based on independent identically distributed random variables which may be right-censored are considered. The equations which appear to be natural analogues of the uncensored equations require full distributional assumptions, and a distribution-free modification based on the product-limit estimator is suggested. It follows from self-consistency that the resulting estimating functions are simply means obtained from the product-limit estimator. The asymptotic variances of the estimators obtained from the equations are derived and compared.


In this paper, we suggest the advanced method of methane hydrate formation by cyclodextrin solutions. The structures of the methane hydrate were experimentally investigated by Raman spectroscopy. The induction time of the methane hydrate formation becomes by shorter 10–30 times and formation rate become by faster 2–4 times originated in the increased methane concentration of hydrate formation water by adding cyclodextrins. The results by the Raman spectroscopy indicate that the structure I methane hydrate is produced and methane molecules exist in both Large and Small cages.Copyright © 2007 by ASME


The welfare reform legislation of 1996 significantly reduced noncitizens' access to public benefits. Research has indicated that welfare reform has had unintended "chilling effects," whereby even those noncitizens who remain eligible for benefits do not utilize them because of fear and confusion. Although refugees were exempted from the benefit restrictions for a certain period following arrival, recent research has suggested that they too may have experienced chilling effects. This study was conducted to more accurately determine whether this has occurred, through the use of time-series data for a sample of refugees who remain eligible for public benefits. The findings did not provide strong evidence that welfare reform has created chilling effects for refugees, although the possibility cannot be ruled out.


This paper puts forth an expanded typology of definiteness marking, which includes not only 'strong' and 'weak' but also 'super-weak'. It also proposes a methodology for identifying 'super-weak' definites, and applies it to Ṭuroyo, an endangered Semitic language. Data from questionnaires and interviews shows that Ṭuroyo's definite article has a very wide distribution, including anti-uniqueness effects with exclusives, suggesting 'super-weak' status. Syntactic factors also affect their distribution: We find definiteness-spreading uses with demonstratives and possessives, even in non-contrastive environments, and superlative adjectives appear to compete for the article's syntactic position. On the semantic side, we propose that Ṭuroyo's definiteness-markers are not 'weak' but 'super-weak' articles. To explain their anaphoric uses, typical of 'strong' articles, we propose that the typology is arranged as a cline ordered by entailment, so that stronger articles entail weaker ones.


INTRODUCTION:
The abducens nerve or abducent nerve (the sixth cranial nerve, also
called the sixth nerve or VI) is a somatic efferent nerve that controls the
movement of a single muscle, the lateral rectus muscle of the eye, in humans.
In most other mammals it also innervates the musculus retractor bulbi, which
can retract the eye for protection. Homologous abducens nerves are found in
all vertebrates except lampreys and hagfishes.
The human sixth cranial nerve is derived from the basal plate of the
embryonic pons.
The Latin name for the sixth cranial nerve is nervus abducens. The
Terminologia Anatomica officially recognizes two different English
translations: abducent nerve and abducens nerve. Either term is correct.
AIMS AND OBJECTIVES:
Primary Objectives:
1. To determine the etiology of sixth cranial nerve palsy.
2. To analyze the clinical course of the disease.
3. To alleviate diplopia.
4. To regain full range of binocular extra ocular movements.
5. To align eyes in primary gaze surgically.
Secondary Objective:
To improve the cosmetic appearance of the patients.
MATERIALS AND METHODS:
Subject Selection : 57 eyes of 50 patients attending
Ophthalmology OPD diagnosed with isolated
6th cranial nerve palsy during two year
period. (June 2009 and June 2011).
Inclusion Criteria : 1. All patients with diplopia due to lateral
rectus palsy.
2. Patients of all age groups
Exclusion Criteria : 1. Associated neurological manifestations
2. Duane's retraction syndrome
3. Restrictive causes of esodeviation
4. Sensory esotropia
CONCLUSION:
1. The incidence of isolated sixth cranial nerve palsy had a bimodal peak,
first peak between ages 21 to 30 years and second between ages 51 to
60.
2. Incidence of isolated sixth cranial nerve palsy in males was higher than
females in our study. Ratio of Males : Females was 1.7 : 1
3. Right and left eyes were almost equally affected in our study.


Hydrocele of canal of Nuck is a rare disease of females. Canal of Nuck is a patent processus vaginalis in women. It usually gets obstructed but sometimes it can remain patent and forms a hydrocele or hernia in inguinal region. Hydrocele of the Canal of Nuck is usually a slow growing painless swelling which is in inguinal region but it can extend from inguinal region to labia majora. Imaging investigations such as ultrasound, CT scan, and MRI help in reaching the diagnosis if not, then it is confirmed on operation and histopathology of the sac wall. Treatment is the excision of the hydrocele. We report a case of right sided hydrocele of canal of Nuck due to its rarity and abnormal size.


The COⅠ genes in two newly discovered chicken breeds(Jinhu silky and Wahui) and indigenous chicken breed(Langshan) were amplified by sequencing,in order to post the genetic diversity of these two newly discovered resources and their heredity relation with other chicken breeds.The results showed that the selective sequence of COⅠhad 10 SNPs and 7 haplotypes,3 SNPs were specific mutation sites,5 haplotypes were specific haplotypes.The average nucleotide diversities of Jinhu silky,Wahui and Langshan were 0.068%,0.051% and 0.0369%,respectively;the haplotype diversities of them were 0.4167,0.3030 and 0.9000,respectively;the genetic diversity of Langshan was higher than the two newly discovered breeds.The Kimura 2-parameter distances between the breeds ranged from-0.002 to 0.236.The genetic distances of intrapopulation were less than that of interpopulation.It was feasible and effective to identify chicken breeds using DNA barcodes of COⅠ gene.


Low profitability of hardwood rangeland manage ment, and oak tree harvesting for firewood markets and forage enhancement has led to concern about the long-term sustainability of the oak resource on rangelands. New markets for recreational hunting may give value to oaks for the habitat they provide for game species, and broaden the economic base for managers. A ranch level optimal control model has been developed to assess optimal oak tree canopy and livestock stocking under different biological and economic conditions. The impact of recreational hunting on management was also assessed. In general, hunting improved the economic return on hardwood rangelands, and resulted in lower oak harvest levels and lower livestock stock ing. The policy implication is that public concern over oak tree harvesting may be partially alleviated by new markets for recreational hunting on hardwood rangelands.


It is necessary to introduce RTOS into developing D SP application so as to shorten the development period, modularize software and make full use of computation capability about DSP. This paper analyses the adva ntages and functionalities of RTOS and introduces the porting of μC/OSI I on TI C5400 DSK platform. An instance on μC/OSII, coded voice, was d iscussed and compared with implement of traditional method.


Deep learning-based methods for stereo matching have shown superior performance over traditional ones. However, most of them ignore the inherent geometry prior of stereo matching when training, i.e. the reference image can be reconstructed from the second image in the visible regions. The reconstruction can be achieved by backward warping the second image using the disparity map of the reference image, while the visible regions can be calculated by left-right consistency check. This prior is useful especially when the ground truth disparity is sparse (e.g. the outdoor scene such as KITTI 2015). This prior incorporated into a two-stage end-to-end training process, both of which try to minimise the end-point-error with respect to the sparse ground truth disparity (supervised learning), and the reconstruction error (self-supervised learning). The predicted disparity and the reconstruction error of the first stage act as additional information, and are fed to the second stage to make further use of this prior knowledge to improve performance. Experiments on the challenging KITTI 2015 dataset show that the method improves the results in the foreground region, and ranks first among all the published methods on the D1-fg metric.


To the Editor Neuropeptides, expressed by both invertebrate and vertebrate nervous systems (Grimmelikhuijzen and Hauser, 2012) play critical roles in both synaptic and non-synaptic signalling mechanisms regulating the functions of nervous, endocrine and immune systems (Nässel and Larhammar, 2013). In contrast to vertebrates the invertebrate nervous system contains high number of neurosecretory cells that produce and elaborate several neurohormones (most of them are peptides) that act on peripheral tissues e.g., body wall muscles, alimentary canal, excretory and genital organs (Taghert and Nitabach, 2012). However, some of the neuropeptides are neuromodulators in the central nervous system mediating the firing mechanism and synaptic transmission of neurons (van den Pol, 2012). While broad range of neuropeptides is known from some invertebrates like planarians, roundworms, insects or molluscs (De Haes et al., 2014), but less is known from the annelids, especially from earthworms. Most of the neuropeptides, like proctolin, FMRFamide-like peptides, neuropeptide Y (Lengvari et al., 2001), substance P and ACTH-like peptide (Aros et al., 1980), believed to be regulator molecules in earthworms had only been identified by immunocytochemical stainings. There are only a few neuropeptides, e.g., CAPA-peptides (Herbert et al., 2009) and pituitary adenylate cyclase activating polypeptide (PACAP)-like peptides (SomogyváriVígh et al., 2000) which expression, pattern and function have investigated by various experimental protocols in details. PACAP is a highly conserved member of the VIP/secretin/glucagon peptide family found in neuronal elements of both the CNS and several peripheral tissues of vertebrates. It acts as a pleiotropic neuropeptide via three heptahelical Gprotein-linked receptors, one PACAP-specific (PAC1) ___________________________________________________________________________


All great cities inspire great literature, but no other city has so consistently stimulated the literary imagination as London. Over the centuries writers, poets, historians, artists, and simple observers have chronicled the life and growth of the capital from its humble beginnings to the teeming metropolis it is today. In his sparkling anthology Paul Bailey has captured the essence of its allure for visitors and inhabitants from the Middle Ages to the present day with wit, humour, and pathos. Among the many contributors are those whose evocations of the city have forever fixed it in the popular mind: Charles Dickens's descriptions of fog-bound London streets, the bustle and hustle of the Victorian city; Ben Jonson's satires on London low-life; William Wordsworth rhapsodizing on the view from Westminster Bridge; George Bernard Shaw's archetypal Cockney, Eliza Doolittle. Less well known but equally vivid are descriptions of everyday life for the down and out and the aristocrat, of the museums, theatres, galleries and churches, the restaurants and pubs, the parks and institutions, the topography of London mapped out in unforgettable verse and prose. The great set pieces, Daniel Defoe's description of the Plague year, John Evelyn's and Samuel Pepys's daily records of the Great Fire, are among several other eye-witness accounts of coronations and funerals, unequalled in their immediacy. The bemusement of foreign visitors, the joys and horrors of London buses and the London Underground, the sprawl of the suburbs and the excitement of the City, all add to the dazzling panorama. This book is intended for general anthology buyers, readers interested in the literature and history of London, tourists, fans of Paul Bailey.


The structural and electrical properties of Al₂O₃/La₂O₃/Al₂O₃ (ALA) films using a tunnel oxide annealed at various temperatures were investigated. The program/erase properties of the ALA films using the tunnel oxide annealed at 600℃ were superior to others. The program/erase voltage and time of the ALA films using the tunnel oxide annealed at 600℃ were 11 V for 10 ㎳ (program) and ?11 V for 100 ㎳ (erase), respectively, and the corresponding memory window was about 1.59 V. In the retention test, the Vth distributions of all films were not changed up to about 10⁴ cycles. In this study, all data showed sufficient characteristics to be used in flash memory devices.


The Sa'dan Toraja are an ethnic group who live primarily on the Indonesian island of Sulawesi. This rigorous academic study by Michaela Budiman examines the deep cultural shifts among the Toraja during the last century through the lens of their most important ritual-funerals. This book specifically addresses the conversion of the Toraja from their indigenous religion, Aluk Todolo, to Christianity and how this shift is reflected in their contemporary funeral practices and understanding of both death and grief.


Abstract : Current portable instruments utilizing a bistatic technique for measuring cloudbase heights are subject to large errors when the ceiling is greater than five times the instrument baseline. A hand-held, portable, low- cost, battery-operated laser range finder was evaluated for use as a cloud-base height instrument. The performance of the device was compared with the results obtained from several instruments designed as ceilometers, an AN/GMQ-13A rotating beam ceilometer, an Impulsphysik ceiloskop, and an ASEA ceilometer. For ceilings between 180 and 400 meters, data from all instruments showed the same long-term trends and similar short-term variators. For ceilings above 400 meters, the ceiloskop showed large errors compared to the other ceilometers; while the readings obtained from AN/GMQ-13A, the ceilometer, and the AN/GVS-5 compared favorably.


Posttransplant lymphoproliferative disorder (PTLD) is a known complication of solid organ transplantation. Diffuse large B‐cell lymphoma (DLBCL) is frequently seen in this setting. However, CD30+ DLBCL with sinusoidal pattern of involvement has not been reported in pediatric PTLD. We are reporting a 9‐year‐old female child presented with diffuse lymphadenopathy postheart transplantation. The pattern of involvement was suggestive of anaplastic large cell lymphoma, but the malignant cells were positive for B‐cell markers and negative for anaplastic lymphoma kinase. The patient was treated aggressively with multiagent chemotherapy and rituximab. Accurate diagnosis in PTLD is paramount in making management decisions.


Strong K(alpha ) emission is observed from a plasma produced by a high intensity contrast, picosecond, p-polarized laser pulse. The K(alpha ) emission is found to be induced by hot electrons, which have a temperature of around 3 keV and carry up to 20% of the laser energy. Due to the relatively high K(alpha ) yield, small source size, and short duration of emission, a high-peak spectral brightness x-ray source is obtained.


The paper reports on studies conducted by the Ontario (Canada) Ministry of Transportation and Communications to improve sampling of bituminous hot-mix for roads and to better understand the variables that determine the density of compacted pavements. To determine if it was possible to sample the material at the hot plant an experiment was designed to compare two method of sampling the material from the pile in the truck box with the standard sampling method already in use -- that of taking a sample from the road behind the paver. The compaction study employed a nuclear density meter in an experiment designed to measure density rapidly and to evaluate each source of variation.


In remarks to local business economists, Philadelphia Fed President Patrick Harker gave his economic outlook and discussed new research that may help to explain why business dynamism has declined in the U.S. for several decades.


ABSTRACT In this article, the discussion of loss and its relationship to learning is based on the analysis of interview data from 39 older adults in Hong Kong and 40 in Australia. The focus of the research was on ageing and learning. The phenomenon of life changes, specifically losses, and their relationship to learning was frequently mentioned, and this theme is described here. Three different kinds of loss were identified in the data as motivators for organized or nonorganized learning or for negatively affecting learning. These included loss of aspects of health, of job, or of partner. The results are potentially useful to policy makers and learning providers in encouraging older adults to engage in learning as one way of coping with loss.


Basic research is the bedrock of science and technology (S&T) progress and industrial transformation, and the cornerstone to making China a world leader in S&T. In the new round of the technological and industrial revolution, basic research is assuming an increasingly prominent role. Aiming at becoming a world leader in S&T by 2050, China should maintain a clear understanding of its development stage and challenges, consolidate basic research, and enhance its original innovation capability.


Objective: To evaluate the long-term cure rates and perioperative and post-operative complication rates after treatment of female urinary stress incontinence with the minimally invasive transobturator tape procedure. Methods: Between 1/01/2007 and 31/12/2008, a transobturator vaginal tape was inserted in 30 women with clinical evidence of SUI. Preoperative evaluation included complete history, physical examination, urine analysis and a questionnaire assessing the subjective perception of the women on their continence status. Results: Thirty consecutive women who fulfilled the inclusion criteria underwent TOT procedure. The mean age was 55years (range 41-60). The follow up time was of 2 years . One patient was lost to follow-up after 12 months and 2 women did not come for the 24-month evaluation. Our results demonstrate a 93.3% cure or improvement rate after 6 months, 93.1% after 12 months and 92.85% after 24 months. Mesh erosion was seen in 2 women (6.6%), whereas rate of urinary tract infection and transient retention of urine was 3.3% each. Conclusion: The transobturator vaginal tape is a safe, easy and efficient surgical procedure for the treatment of female SUI.


Elongation factor‐1 (EF‐1) is a cellular protein that plays a role in protein synthesis by mediating the transfer of aminoacyl‐tRNA to 80S ribosomes. It is comprised of four subunits: α, β, γ, and δ. EF‐1γ is a substrate for the maturation‐promoting factor, which determines entry into the M‐phase of the cell cycle in all eukaryotic cells. Previously, the authors showed that EF‐1γ RNA is overexpressed in a high proportion of colorectal carcinomas. At that time, there were no antibodies to EF‐1γ, so the EF‐1γ protein could not be examined. Because levels of RNA do not always parallel the levels of the protein it encodes, it was important to develop antibodies to EF‐1γ to examine its expression at the protein level in colorectal carcinoma.


The petrographic study of rocks and some few outcrops revealed the great diversity of volcano-plutonic formations. Indeed, magmatism of the Yaour


Eight proturan species were collected from Doi Suthep-Pui National Park, northern Thailand. Among them, three species are new to science: Baculentulus chiangmaiensis, Kenyentulus suthepicus, and Eosentomon chiangmaiense. Baculentulus ogawai (Imadate) is redescribed.


3-Aryl- and 2-aryl-1,4-benzodioxane derivatives of type 4d and 5d are excellent starting compounds for the synthesis of natural flavano- and neolignans. The syntheses of 4d and 5d were achieved with high regioselectivity by oxidative coupling of caffeic acid ethyl ester (2h) and coniferyl alcohol (1c) in the presence of a silver salt (oxide, carbonate) and potassium hexacyanoferrate(III), respectively.

Regioselektive Synthese von 2-und 3-Aryl-1,4-benzodioxanen

Fur die Synthese naturlich vorkommender Flavano- und Neolignane eignen sich in hervorragender Weise 3-Aryl- bzw. 2-Aryl-1,4-benzodioxan-Verbindungen des Typs 4d und 5d als Ausgangsstoffe. Ihre Synthese gelang mit hoher Regioselektivitat durch oxidative Kupplung von Kaffeesaure-ethylester (2h) und Coniferylalkohol (1c) mit Silber-Salz (Oxid, Carbonat) bzw. Kaliumhexacyanoferrat(III).


Until quite recently, research on gender and interaction revolved primarily around the use of gendered categories and third person reference in the English language. Based on data from Greek talk-in-interaction, the aim of this paper is to point to some non-referential aspects of gendering. More specifically, adopting a conversation analytic perspective, instances of collective and individual self-reference – in itself not gendered in Greek – are analysed and shown to acquire gendered meanings in the specific context, without the deployment of terms or categories marked by grammatical or lexical gender. Such self-genderings impact on the gendering of recipients via the reflexivity of participants' roles in interaction. Gendering oneself and others thus emerges as a dynamic process that fully exploits the inherent features of interaction, in interplay with the specific means that a language makes available to its users.


Traditional axisymmetric casing treatment always reduces the efficiency while improving the stall margin of a compressor.Five non-axisymmetric casing treatments with different circumferential block numbers were designed.It was proved that different numbers of treating blocks influence compressor stall margin little,but obviously change the efficiency and total pressure rise.Both of which rise is followed by a gradual decline at the process of increasing the number of treating blocks.An optimized non-axisymmetric casing treatment can not only increase the stall margin of compressor by 13%,but also raise the max efficiency by 0.8%.The cause for this is analyzed as that non-axisymmetric distributed treating slots change the unsteady exciting signal for the tip flow.Based on the Unsteady Cooperative Flow theory,the low-frequency exciting signal from the optimized non-axisymmetric casing treatment can coupled with the complicated vortex tip flow in the compressor.


Mr Nuwaselo Nuwapai tells the story of a fearless warrior called Sikana. He was a strong masculine soldier who helped the Japanese fight in the war and also known to be the flag bearer of the Japanese army.


OBJECTIVE
Cytokine receptor-like factor 2(CRLF2) plays an important role in the development of normal B lymphocytes, which can mediate early B cell proliferation and survival. The aim of this study was to investigate the mutations of CRLF2 and its clinical significance in adult patients with acute lymphoblastic leukemia(ALL).

METHODS
Exons of CRLF2 were amplified, then the DNA was purified and sequenced; the frequency, position, types and clinical significance of CRLF2 mutations were analyzed.

RESULTS
6 types of genetic alterations in CRLF2 were found, among them the R186S prompted better prognosis, while L86I, F232F and W255C associated with poor prognosis.

CONCLUSION
CRLF2 mutations may play an important role in the development and progressions of adult patients with ALL, and these genetic abnormalities may associate with clinical outcome.


The aim of this review is to analyze the usefulness of the diagnostic sepsis marker – presepsin. Materials and methods . A search for relevant publications on presepsin was conducted using  the PubMed database of medical and biological publications and the eLIBRARY.com scientific electronic library. The review includes 42 Russian-language and English-language  sources. Particular attention was paid to comparative studies on the role of presepsin and other bio-markers in the diagnosis of sepsis. Results. The conducted analysis brought about heterogeneous results. Presepsin was highly  sensitive in detecting late neonatal sepsis, burn sepsis, and also reflected the efficacy of therapy  in septic premature babies and severely burned patients. However, presepsin was not confirmed  as a marker of the disease severity or a prognostic marker of neonatal sepsis. The measured  levels of presepsin are significantly influenced by renal function; therefore, in patients with renal disease, other sepsis markers should be used or the normal presepsin levels should be  adjusted to higher values. Most authors recommend using presepsin in a combination with other markers of sepsis. Considering that presepsin has a good potential of detecting early signs of sepsis and also of monitoring the effects of antimicrobial therapy, further careful studies on this marker are warranted. Conclusion . Based on the present review, more studies are needed to determine and compare  the diagnostic accuracy of various sepsis markers (C-reactive protein, procalcitonin, presepsin).


The aim of the present experimental research was to determinate the antimicrobial effect in vitro of the essential oil and the aqueous extract of Cinnamomum zeylanicum (canella) over Candida albicans and Streptococcus mutans. For this was inoculated a total of 288 Petri plates to determine the minimum inhibitory concentration (MIC) and the antimicrobial effect evaluating six concentrations for the two presentations of Cinnamomum zeylanicum. The MIC was measured as Colony Forming Units per milliliter (CFU / ml) while the antimicrobial effect was determined by the disk diffusion method, making reading in millimeters (mm).The results showed that the MIC of the aqueous extract and essential oil of cinnamon on the growth of Candida albicans was of 1 mg / ml. The MIC of the aqueous extract and essential oil of cinnamon on the growth of Streptococcus mutans was 0,8 mg / ml and 1 mg / ml,


Various lines of evidence support conflicting interpretations of the timing, abruptness, and nature of climate change in the Great Plains during the Pleistocene–Holocene transition. Loess deposits and paleosols on both the central and northern Great Plains provide a valuable record that can help address these issues. A synthesis of new and previously reported optical and radiocarbon ages indicates that the Brady Soil, which marks the boundary between late Pleistocene Peoria Loess and Holocene Bignell Loess, began forming after a reduction in the rate of Peoria Loess accumulation that most likely occurred between 13.5 and 15 cal ka. Brady Soil formation spanned all or part of the Bølling-Allerød episode (approximately 14.7–12.9 cal ka) and all of the Younger Dryas episode (12.9–11.5 cal ka) and extended at least 1000 years beyond the end of the Younger Dryas. The Brady Soil was buried by Bignell Loess sedimentation beginning around 10.5–9 cal ka, and continuing episodically through the Holocene. Evidence for a brief increase in loess influx during the Younger Dryas is noteworthy but very limited. Most late Quaternary loess accumulation in the central Great Plains was nonglacigenic and was under relatively direct climatic control. Thus, Brady Soil formation records climatic conditions that minimized eolian activity and allowed effective pedogenesis, probably through relatively high effective moisture. Optical dating of loess in North Dakota supports correlation of the Leonard Paleosol on the northern Great Plains with the Brady Soil. Thick loess in North Dakota was primarily derived from the Missouri River floodplain; thus, its stratig raphy may in part reflect glacial influence on the Missouri River. Nonetheless, the persistence of minimal loess accumu lation and soil formation until 10 cal ka at our North Dakota study site is best explained by a prolonged interval of high effective moisture correlative with the conditions that favored Brady Soil formation. Burial of both the Brady Soil and the Leonard Paleosol by renewed loess


Nowadays, there is an abundance of data involving images and surrounding free-form text weakly corresponding to those images. Weakly Supervised phrase-Grounding (WSG) deals with the task of using this data to learn to localize (or to ground) arbitrary text phrases in images without any additional annotations. However, most recent SotA methods for WSG assume an existence of a pre-trained object detector, relying on it to produce the ROIs for localization. In this work, we focus on the task of Detector-Free WSG (DF-WSG) to solve WSG without relying on a pre-trained detector. The key idea behind our proposed Grounding by Separation (GbS) method is synthesizing 'text to image-regions' associations by random alpha-blending of arbitrary image pairs and using the corresponding texts of the pair as conditions to recover the alpha map from the blended image via a segmentation network. At test time, this allows using the query phrase as a condition for a non-blended query image, thus interpreting the test image as a composition of a region corresponding to the phrase and the complement region. Our GbS shows an 8.5% accuracy improvement over previous DF-WSG SotA, for a range of benchmarks including Flickr30K, Visual Genome, and ReferIt, as well as a complementary improvement (above 7%) over the detector-based approaches for WSG.


Anderson-Fabry disease (AFD) is a rare X-linked inherited lysosomal storage disorder caused by GLA gene mutations. With the progression of the disease, end organ damages (such as renal and cardiac) will impair quality of life. For nephrologists, it is necessary to improve the early diagnosis ability of AFD and the ability to assess the involvement of multiple organs (especially the heart). Cardiac magnetic resonance (CMR) is more accurate than echocardiography in measuring myocardial thickness and mass. Moreover, with the gradual maturation of T1 Mapping and gadolinium-enhanced cardiac magnetic resonance, CMR has also been applied to evaluate cardiomyocyte injury. In this study, clinical data of patients with AFD were collected in order to study the value and advantages of advanced CMR technologies in evaluating cardiac function, cardiac structure and cardiomyocyte injury.

 In this prospective observational study, clinical and echocardiography data were collected from patients with AFD diagnosed at this center from January 2022 to September 2022. T1 Mapping and gadolinium-enhanced cardiac magnetic resonance were used to evaluate the cardiac function and the degree of cardiac structural lesions, and to analyze characteristic CMR findings of cardiac involvement in AFD. To clarify the value of CMR for the assessment of cardiac involvement in AFD compared with echocardiography.

 13 patients (five women, eight men) with AFD were included (Table 1). When diagnosing reduced ejection fraction, two (15.4%) met CMR, and zero (0%) met echocardiography. When diagnosing left ventricular hypertrophy, 12 (92.3%, 18.56±2.74mm) met CMR, and ten (76.9%, 16.37±2.71mm) met echocardiography. Compared with CMR, echocardiography can significantly underestimate the severity of left ventricular hypertrophy (P = 0.043). Using T1 Mapping and gadolinium-enhanced cardiac magnetic resonance, characteristic CMR findings of cardiac involvement in AFD were found in all patients (Fig.1), included decreased T1 values (12 cases, 92.3%, 1104.00±44.69ms) and late gadolinium enhancement (LGE) (six, 46.2%).

 Characteristic CMR findings of cardiac involvement in AFD are left ventricular hypertrophy, decreased T1 values, and LGE associated with myocardial fibrosis. Advanced CMR holds promise in subclinical detection of AFD.


Two new oleanene sapogenols, abrisapogenols A (1) and C (2), have been obtained from the methanolysate of the crude saponin fraction. They have been effective for treating a hepatic injury induced by CCl4, in Abri Herba, the whole plant of Abrus cantoniensis HANCE (Leguminosae), Also a novel saponin, abrisaponin I (3) has been obtained from the same saponin fraction.


Until this period of the evening, the duties of hospitality and the observances of religion had prevented familiar discourse. But the regular offices of the housewife were now ended for the night; the handmaidens had all retired to their wheels; and as the bustle of a busy and more stirring domestic industry ceased, the cold and selfrestrained silence, which had hitherto only been broken by distant and brief observations of courtesy, or by some wholesome allusion to the lost and probationary condition of man, seemed to invite an intercourse of a more general character.1


a judge.&dquo; The responsibility is humbling, frustrating, frequently disheartening, occasionally satisfying. The principal purpose of sentencing an offender is to protect society. If society can be protected and the accused rehabilitated in the same procedure, so much the better. In primitive society, punishment satisfied the vengefulness of the injured and his family. When the aggressor and the injured chose a third person to decide between them, and their neighbors undertook to see that his decision was enforced, society took its first step toward civilization. The group shared the vengeance and used punishment to protect itself. Through the ages the emphasis in sentencing has shifted from avenging to protecting society, and in modern times there is an additional aim: to rehabilitate. During this slow process, the judge became the spokesman for the group as the guardian of its right to protection on the one hand, and as the protector of the accused on the other. As spokesman for the group, the judge must remember that the mores of a people are often more influential than its laws. The tendency to conform lies deep in most normal people, who have a fear of group disapproval. The judge must strive to maintain the standard of morality of his community; if possible, he must raise it. This is the real test of a judge. He must gird himself against social pressure which may cause him to lose his objectiveness and tempt him to join the group in its natural revulsion to an atrocious crime. The judge who indulges in cruel and sadistic remarks as part of his sentence serves no end except to erode the patience of the community. In the offender, such remarks may arouse either vindictiveness, which will destroy any possibility of repentance, or they may stimulate a masochistic compulsion, which will contribute to further deterioration. There are, for example, the judge who embellished his sentence with the declaration, &dquo;I therefore sentence you to solitary confinement at hard labor on bread and water for the rest of your natural life,&dquo; and the judge who asked, &dquo;How long is it since you've seen your mother?&dquo; and then added, &dquo;Well, it'll be forty years before you see her again.&dquo; On a lesser plane there is the traffic judge who sentences a sensitive violator to sit in the morgue or to view


The Arctic regions of Russia are primarily focused on the extraction of raw materials, and the mining sector has witnessed an increase in added value in recent years. On average, 84% of taxes and fees contributed to the budget system of the Russian Federation originate from the Arctic's mining sector, which highlights the importance of analyzing the activities of this sector. This article aims to assess the industrial potential of the mining sector in the Russian regions located in the Arctic zone. Such an assessment identifies the potential uses of a combination of resources to enhance the economic development of these regions. The study employed various theoretical methods such as generalization, comparison, and systematization, along with empirical analysis including statistical observation and graphical interpretation. The research draws upon scientific publications related to the industrial potential of Russian regions, utilizing data from the Federal State Statistics Service to evaluate the mining sector's potential in the Arctic regions. The article discusses the advantages and limitations of current methodologies for ranking Russian regions based on the industrial potential of the mining sector. Building upon the study, a comprehensive methodology is proposed, which involves assessing the industrial potential of the mining sector through the calculation of indices based on 17 indicators grouped into five domains: materials and technology, innovation and investment, finance, labor, and infrastructure. The proposed methodology was applied to analyze the industrial potential of the mining sector in four Russian regions located within the Arctic zone for the period from 2017 to 2021. The findings indicate that the Murmansk region exhibits the highest industrial potential in Russia's Arctic mining sector,with the Yamalo-Nenets Autonomous Okrug ranking second. The Nenets Autonomous Okrug and Chukotka Autonomous Okrug display relatively low potential in the mining sector.


A new structure of rotating stall with unusual large-number stall cells ( up to 7 ) has been detected experimentally in a high performance single stage centrifugal compressor system with backswept impeller and vaned diffusers. The number of stall cells is firstly identified by a phase analysis of pressure signals obtained from fast response dynamic transducers located at different circumferential positions on the shroud wall, and then verified by comparing the resulting frequencies of blade vibration with that measured from blade mounted strain gages. Up to 6 transducers in one radial position have been used for more certainty of the phase analysis. For the case of intermittent stall patterns, the frequency analysis of pressure and blade vibration signals is performed separately for sections with different characters of oscillation to avoid the smearing effect if signals of the whole pattern are averaged. As a result, the large-number stall cells, numbered 4-7, were determined in the speed


A / Duck / Shandong / 093 / 2004 was reported to be a reassorted H5N1 avian influenza virus.A phylogenetic study of it was conducted to identify its genotype.A Bayesian phylogenetic analysis of eight separate gene segments and a neighbor-joining analysis of its whole genome demonstrated that it was an the X genotype virus,although this genotype was reported to be replaced by genotype Z in Southern China in 2002.


I read with interest about staff at Gartnavel Hospital in Glasgow wearing red tabards to prevent interruptions while dispensing medicines (news February 21).


The article indicates that some problems in schooling,family education,social ecology,stu- dents' self-education,etc.,are factors leading to the insufficiency of students'responsibility.It also gives some solutions to improve the education of students' responsibility,i.e.,constructing the environ- ment for the students' responsibility education and"San Yu Ren"educational system,which guides students to develop the awareness of responsibility by themselves.


The main objective of this paper is to present two different experiments that have been developed to successfully demonstrate transient heat conduction phenomena. The first experiment illustrates the approximate measurement of transient local heat flux within a solid wall subjected to a surface quench. It utilizes a unique type of conduction apparatus that has been under development in the Department of Mechanical and Nuclear Engineering at Kansas State University (KSU), which overcomes many of the difficulties normally associated with laboratory demonstrations of steady-state and transient heat conduction. The second experiment involves a moving laser heat source used in a metal cutting operation. Measurements of the transient temperature history resulting from the moving laser heat source are compared directly with predictions from conduction theory. The unique industrial manufacturing facilities available on the campus of KSU make possible the practical engineering laboratory demonstration of this important process. Each experiment offers features not normally available from commercial heat transfer apparatus.


A facile and efficient route for the synthesis of tetrasubstituted imidazoles from amidines and chalcones via FeCl3/I2-catalyzed aerobic oxidative coupling has been developed. This new strategy is featured by high regioselectivity and yields, good functional group tolerance, and mild reaction conditions.


Collaboration is essential for some types of research, and some agencies include collaboration among the requirements for funding research projects. This makes it important to analyse collaborative research ties. Traditional methods to indicate the extent of collaboration between organizations use co-authorship data in citation databases. Publication data from these databases are not publicly available and can be expensive to access and so hyperlink data has been proposed as an alternative. This paper investigates whether using machine learning methods to filter page types can improve the extent to which hyperlink data can be used to indicate the extent of collaboration between universities. Structured information about research projects extracted from UK and EU funding agency websites, co-authored publications and academic links between universities were analysed to identify if there is any association between the number of hyperlinks connecting two universities, with and without machine learning filtering, and the number of publications they co-authored. An increased correlation was found between the number of inlinks to a university's website and the extent to which it collaborates with other universities when machine learning techniques were used to filter out apparently irrelevant inlinks.


As a living kidney donor coordinator, I was interested in an opinion piece published in the BMJ by Dundee University researcher Sue Rabbitt Roff.