2562Background: The PARP inhibitorolaparib (Lynparza) is being evaluated in combination with other anticancer agents. We investigated the steady-state (ss) PK effects and safety of olaparib (tablet) co-administered with the anti-hormonal agents tamoxifen, anastrozole, or letrozole. Methods: An open-label, nonrandomized study was conducted in 79 eligible patients with advanced solid tumors. During three consecutive treatment periods, patients received: (1) olaparib 300 mg twice daily (bd) for 5 days, followed by a 4-day washout period; (2) either tamoxifen 60 mg once daily (qd) for 4 days (loading dose) then 20 mg qd to day 26 (n=30), or anastrozole 1 mg qd to day 19 (n=23), or letrozole 2.5 mg qd to day 38 (n=26); (3) same as treatment period 2 concomitantly with olaparib 300 mg bd for 5 days. Blood samples for PK analysis were taken at ss. Safety was monitored throughout. Results: Olaparib AUC0-t and Cmax decreased by 27% and 20%, respectively, when co-administered with tamoxifen. Anastrozole and letrozo...


A low power zenith looking Ka Band dual polarization Cloud Radar is designed and fabricated by Society for Applied Microwave Electronics Engineering and research (SAMEER) to study the clouds during monsoon. This radar is installed on the terrace of the SAMEER building and conducted test operations in single polarisation mode during monsoon period(June to September, 2013-2015). The system is observed clouds upto 10 km during the observation period. Sample observations in different cloudy conditions are presented in this study.


This paper presents the application of multilayer perceptron baed on the Levenberg-Marquardt algorithm to odour pattern classification and concentration estimation using odour sensing system. We adapted the Levenberg-Marquardt (L-M) algorithm having advantages both the steepest descent method and Gauss-Newton method instead of the conventional steepest descent method for the simultaneous classification and concentration estimation of odours. It is confirmed that the multilayer perceptron based on the L-M algorithm is capable of not only the identification of odour classes, but also the prediction of odour concentrations for volatile chemicals with different concentration levels simultaneously throughout the experimental trails.


To advance ATM research as a science, ATM research results should be made more comparable. A possible way to do this is to share tools and data. This paper presents a project that investigates the feasibility of a fully open-source and open-data approach to air traffic simulation. Here, the first of the two main challenges is to achieve a high fidelity, without using proprietary data, e.g. for aircraft performance. The second challenge is to increase the adoption by the community by keeping the program easy to use, easy to modify, multi-platform, downloadable for free and running stand-alone on relatively simple systems. The approach chosen by the project is to investigate this feasibility by trying to start the development. The paper describes the many hurdles to be overcome when using a fully open-data and open-source policy in this area.


Bachelor work conducts the study of communication strategy of non-profit organization Instituto Portugues da Juventude in Portugal. Theoretical part considers the knowkedge from the fields of non-porfit sector in Czech republic, in European union and in Portugal, as a site of action of chosen organization. In a practical part is the theoretical knowledge applied to Instituto Portugues de Juventude and the facilities of the communication strategy of the organization are analyzed. In the work is one important part devoted to the activities and the structure of this non-porfit organization, what gives us a possibility to compare non-porfit sector in our and the foreign country.


Compared with traditional software testing, Web application testing is quite different. It has become increasingly important to choose appropriate criteria during the testing. This paper presents a set of test adequacy criteria for FSM-based Web application, and proposes two new test criteria: complete function interaction coverage criteria and function loop interaction coverage criteria. Besides, an axioms system is proposed to assess the FSM-based Web application test coverage criteria. From this axioms system, some useful conclusions are educed as a guide for software engineers in practical testing application.


This paper studies the banks' decisions to self-regulate their activities and their selection of the financial markets where they raise their capital. We show that in an economy with a single financial market, self-regulation increases investors' demand for banks' stocks while weaker bank concentration reduces incentives to self-regulate. In addition, in an economy with separate financial markets, banks preferably raise capital in financial markets hosting larger number of investors. However, when self-regulation costs vary across financial places, banks may list their stocks in the country with the smaller number of investors.


The invention relates to a high flow middle and low voltage constant-current stabilizer for preparing liquid chromatogram, particularly a high flow middle and low voltage constant-current stabilizer filled with elastic materials for preparing liquid chromatogram and an application method thereof. The application method is characterized in that: when the flow of a used infusion pump is unstable, if the flow (pressure) is high, the elastic materials in the device are extruded, the deformation is increased, a certain volume of flow is consumed; on the contrary, if the flow (pressure) is low, the deformation of the elastic materials is decreased, the flowing phase in the constant-current stabilizer is extruded to compensate the flow, thus the effect of stabilizing current is achived. According to the invention, by using the elastic materials to buffer the flow and pressure of the flowing phase conveyed by the infusion pump, the pulsation of the infusion pump is effectively weakened, and the stable current is acquired. The device has the advantages of simple structure, easy operation, flexible application, low cost, and can greatly reduce the production cost.


The aim of the paper is to propose simplest advanced indicators to prevent internal imbalances in European Union. The paper also highlights that new methods coming from Machine Learning field could be appropriate to forecast fiscal policy outcomes, instead of traditionnal econometrics approaches. The Stability and Growth Pact (SGP) and especially the 3% limit sets on the fiscal balance purpose to coordinate fiscal policies of the European Union member states and ensure debt sustainability. The Macroeconomic Imbalance Procedure (MIP) scoreboard introduced by the European Commission aims to verify the good conduct of public finances. We propose an analysis of the determinants of the SGP compliance by the 28 European Union members between 2006 ans 2018, through a Support Vector Machine model. More than testing if the MIP scoreboard variables really matter to forecast the risk of unsustainability, we also test a set of macroeconomic, monetary, and financial variables and apply a prior feature selection model which highlights the best predictors. We give some proofs that main primary indicators of the MIP scoreboard are not useful for SGP compliance forecast and we propose new variables to forecast the European Union supranational fiscal rule compliance.


In this paper we study the approximation by splitting techniques of the ordinary differential equation U˙+A U+B U=0, U(0)=U 0 with A and B two matrices. We assume that we have a stiff problem in the sense that A is ill-conditionned and U 0 is a vector which is the discretization of a function with a very high derivative. This situation may appear for example when we study the discretization of a partial differential equation. We prove some error estimates for two general matrices and in the stiff case, where the estimates are independent of U 0 and the commutator between A and B. This paper is dedicated to Michel Crouzeix.


Vibrations are one of many environmental factors that act on a buildings and potentially reduce their lifetime. Current trends in construction industry demands taller and lighter structures, which are also more flexible and having quite low damping value. This increases failure possibilities and also problems from serviceability point of view. Now-a-days several techniques are available to minimize the vibration of the structure, out of the several techniques available for vibration control; concept of using Tuned Mass Damper is a newer one. This study was made to study the effectiveness of using Tuned Mass Damper for controlling vibration of a frames structure. This report proposes a passive control of vibration of single degree of freedom and multi-degree of freedom structural frames subjected to dynamic (wind) excitation and a general understanding of the structural dynamics through MATLAB simulations. Preliminary results on the passive control of the structural response of single degree of freedom (SDOF) and two dimensional multi-storeyed frames using Tuned Mass Damper (TMD) are presented. At first a numerical analysis was developed to investigate the response of a shear building fitted with a tune mass damper. Then another numerical was developed to investigate the response of a 2D frame model fitted with a Tuned Mass Damper and then without Tuned Mass Damper (TDM). From the study it was found that, tuned mass damper can be effectively used for vibration control of structures. Tuned mass damper (TMD) was more effective when damping ratio of the structure is less. Gradually increasing the mass ratio of the tuned mass damper results in gradual decrement in the displacement response of the structure. It is also observed that due to increase in tuned mass damper damping ratio, the movement of tuned mass damper is also decreases.


[See related article at [www.cmaj.ca/lookup/doi/10.1503/cmaj.201197][2]][2]

KEY POINTS
In related research, Stall and colleagues examined the relation between ownership of a long-term care (LTC) facility and the occurrence, extent and mortality associated with outbreaks of coronavirus disease 2019


Galba. There are two verbal echoes of Virgil's Aeneid that do not appear in the other versions. The uniqueness of these evocations combined with an abundance of contextual similarities suggests the allusion's certainty. It is further supported by a possible reminiscence of Virgil's model, the death of Pompey, if we accept that commilito was also one of the last words uttered by Pompey in the account of Asinius Pollio. The allusion is especially compelling because it reinforces the theme of auctoritas, which was a central part of the tradition on Galba's death. It is undeniable that the emperor's peripeteia lent itself to a comparison with Priam and Pompey. However, no writer seems to have developed this connection before Suetonius. The deaths of Priam and Pompey were the final nails in the coffins of Troy and the Republic respectively,25 both phases of the Roman past whose end brought great instability and strife. In the same way, Suetonius' account of Galba's death symbolically punctuates the end of the Julio-Claudian regime with which the biography begins, and the Life ends by mentioning the future dynast Vespasian (Galb. 23). Thus Suetonius' allusion makes the same point as Tacitus' remark that Galba's last year was nearly that of the Roman empire (Hist. 1.11.3).


Functional reconstruction of the oral and maxillofacial defects after ablative surgery of tumors is consi- der to be of utmost importance for the improvement of survival rates and quality of life of the patients. With the advancement in microsurgery and regional anatomy, wide application of dental implants, distraction osteogenesis, CAD/CAM, rapid prototyping, the restorative quality after resection of oral and maxillofacial tumors has been greatly improved, especially in the rehabilitation of oral and maxillofacial contour, but much has to be done in dynamic myofunctional reconstruction, sensory reconstruction, speech and deglutition reconstruction. This paper discusses the up-to-date status and progress trend in oral and maxillofacial reconstruction after ablative tumor surgery in concern with mastication, swallowing, speech and sensation.


The article deals with the content of the essential terms of the contract of lifelong maintenance of a dependent, related to the conflict with a provision of the Civil Code and the Federal Law «On the Minimum Wage». The solution of this legal conflict will avoid a situation of conclusion of shackling agreement about lifelong keeping with maintenance with socially unprotected people.


Background: This Phase IV post-marketing study was conducted to demonstrate the safety and efficacy of sofosbuvir/velpatasvir fixed-dose combination (FDC) in adult Indian patients with HCV infection as per the recommendation of the Drugs Controller General (India). Methods: This single-arm, open-label, multicenter study was conducted across 22 sites in 409 patients in India. All the eligible patients received once-daily sofosbuvir/velpatasvir (400mg/100mg) FDC for 12weeks. Safety was assessed by monitoring the adverse events (AEs) and efficacy was measured by the proportion of patients achieving sustained virological response (HCV RNA <15 IU/mL or undetectable) at 12weeks after the end of the treatment (SVR12). Results: Between October 2018 to June 2020, 409 patients were enrolled. Twenty patients discontinued the study due to consent withdrawal or lost to follow-up. The SVR12 rate was 90.8%. Sensitivity analysis showed consistent results with SVR12 rates of more than 93%. The combination was well tolerated and none of the AEs reported were related to the study drug, requiring dose reduction, or discontinuation of the study treatment. Conclusions: Once daily sofosbuvir/velpatasvir FDC for 12 weeks was found to be safe, well tolerated, and effective in patients with HCV infection. Trial Registration: The trial is registered at clinical trial registry of India with registration number CTRI/2018/08/015359. (CTRI Trial Data)


Summary Batch sorption experiments of U(VI) onto the surfaces of granite rock were carried out. The distribution of the sorbed U(VI) on crushed granite particles was investigated via a sequential chemical extraction method to quantify the amount of U(VI) sorbed on the mineral phases and by X-ray diffraction characterization of dried samples of the remaining minerals after each extraction step to determine the significant mineral phases that sorb U(VI). Chlorite among the constituent minerals, even though being present in a small amount, is assumed to contribute to the strong U(VI) sorption and most of the sorbed U(VI) was weakly bound to the granite surfaces. However, a discriminative amount of the sorbed U(VI) on granite particles was difficult to desorb, in particular, when sorption took place in the alkaline region. The distribution of the sorbed U(VI) both on the fresh intact surface and on the natural fracture surface was also investigated by a X-ray image mapping technique. The result shows that dominant minerals hosting the majority of the sorbed uranium are mica for the intact surface of granite and chlorite for the fracture surface of the granite.


One of the most common iconographic motifs of Roman colonial coinage is the 'foundation scene'. Colonies modelled on Rome were established according to the aratrum ritual, in imitation of the manner in which, according to myths, Romulus founded Rome. Veteran colonies, established between the 1st century BCE and the 2nd century CE, gladly exploited that motif to commemorate the colonial foundation and to manifest their bond with Rome. However, colonies set up under Septimius Severus and later were considered as purely titular foundations. Nevertheless, they also occasionally presented the foundation scene on civic coins. If they were not colonists, the question arises as to the message that such coins conveyed. In this paper, the author makes an attempt to examine the foundation scene on Roman colonial coins from the Near East in the 3rd century CE. The concepts of veteran and titular colonies are contrasted. It is a noteworthy that while the colonies in northern Syria and Mesopotamia (except Rhesaena) never introduced the foundation scene on their coinages, the southern colonies (except Philippopolis) proudly manifested their connections with Rome. Eventually, the foundation scene disappeared from colonial coins of the Near East in the mid-3rd century.


Canadian disability-related policies are shaped within a global system of inequalities, including colonialism and neoliberalism. Using a critical theory framework, this article examines the complicated material inequalities experienced by people with disabilities and evident in the intersections of disability, gender, Indigenousness, race, and age. The collectively held ideas that give context to disability policies are at odds. Human rights protections are found in the foundational documents of Canadian society and part of its international commitments, yet these commitments often become window-dressing for a pervasive logic that it is better to be dead than disabled, and medical assistance in dying legislation supports this choice. While human rights protections are essential, they are not sufficient for decolonizing inclusion. Constructive actions between Indigenous peoples and settlers may help to find new ways of addressing disability and inclusion in Canada.


We present a novel active contour-based tracking algorithm for highly deformable and fast moving curvilinear structures. We propose to use line features as external forces for the active contour for the detection phase in the first frame. For the tracking part, we propose a novel approach of detecting motion of the endpoints and then deformation of the other points using the same active contour model used for detection. Estimating the motion at endpoints only has two advantages. First, motion estimation at endpoints is more robust at endpoints and corners, specially in noisy situations. Other points of the curvilinear structure may suffer from the aperture effect. Second, this will allow large deformation in the body of the structure from frame to frame. As an example application, we have tested our algorithm for biomolecular videos in tracking microtubules which exhibit high deformations in noisy video sequences. Experimental results show both quantitatively and qualitatively the good performance of the tracking algorithm


Abstract : Key decision-makers in the Department of Defense fail to appreciate what commercial industry has known for some time; that accurate and timely financial information can create a strategic advantage. To create this strategic advantage, accounting, and the Planning, Programming, and Budgeting System (PPBS) must be treated as one interrelated financial management system. Strategic plans consider financial management only from the perspective of trying to get the resources to carry out the strategy. Emphasis should be placed on using financial management as a way of evaluating which strategies will be most effective. If financial information were available for strategic decision-making, it could be used to strengthen the Army's request to Congress for resources by building a business case for transformation. Efforts undertaken by the Rumsfeld administration to improve financial management are strategically flawed because they do not link changes in PPBS to the modernization of the accounting systems. Modernizing the accounting systems may improve the accuracy and timeliness of financial data, however it will not yield Rumsfeld's ultimate objective of "reliable, accurate and timely financial information upon which to make the most effective business decisions.


This paper describes the planned Aalto-1 remote sensing campaign. Additionally the satellite itself, its systems and payloads are briefly discussed as is the main payload, the AaSI (Aalto Spectral Imager). Current plans for the mission phases are discussed as well as technical demonstrations under consideration.


Reverse transcriptase is an essential retroviral enzyme that uses RNA‐ and DNA‐directed DNA polymerase activities as well as an RNaseH activity to synthesize a double‐stranded DNA copy of the single‐stranded RNA genome. In an effort to obtain high‐resolution structural information regarding the polymerase active site of reverse transcriptase, we have pursued studies on a catalytic fragment from Moloney murine leukemia virus reverse transcriptase. DNA encoding the catalytic fragment, defined originally by limited proteolytic digestion, has been cloned, and the protein has been expressed and purified from Escherichia coli. The fragment obtained by limited proteolytic digestion and the bacterially expressed fragment retain polymerase activity. Crystallization studies involving nucleic acid complexes with a catalytic fragment from both sources are reported, including variables screened to improve crystals and cryocooling. Three crystal forms of catalytic fragment‐nucleic acid complexes have been characterized, which all contain at least two protein molecules in the asymmetric unit. As isolated, the catalytic fragment is monomeric. This analysis indicates that the enzyme dimerizes in the presence of nucleic acid.


The FingerPrint positioning method is known as a superior method in indoor positioning system that maintains previous signal strength patterns and compares with the measured new real-time signals on APs. In this paper, we analyze active signal phenomena using multi-rate Wi-Fi signals from reference AP which is accessed by multi-users. Some important factors which can effect to the accuracy by comparison among previous signal patterns in the DB and real-time active signals are studied. Some interesting phenomena based on AP connection and disconnection signals are observed.


The energies and number densities of ions emitted from laser-induced plasmas were studied by means of a simple time-of-flight technique. The plasmas were formed on solid elemental targets exposed to focused pulses from a Ti: Sapphire mode-locked laser and regenerative amplifier. The pulse energy and length were 1.0 mJ and 100 fs, respectively, with irradiance at the target of 2 × 1013 W/cm2. Ion kinetic energies, number densities, and mass removal rates were measured as functions of atomic mass, repetition rate, and angular orientation of the target with respect to the detector. Ion velocities varied within the 5.0–30.0 km/s range, corresponding to an average kinetic energy of 20–50 eV. Observed angular distribution of ion energy and number density obeyed the simple cosine function, which varied slightly for different elements. The total number of atoms removed per pulse was about 2 × 1013, while the ion fraction varied in the range of 3.0–5.0% for the majority of studied elements. The estimated total ion kinetic energy per pulse was ∼ 1014 eV, which corresponds to ∼ 1.5% of laser pulse energy. Mass removal rates demonstrated a direct relationship to transport properties of free electrons.


The solubility products of complexes MeI{sub n}{centered dot}18-crown-6 (n = 1, 2; Me = Na, K, Cs, Ca, Sr, Ba) in tetrahydrofuran were determined. It was shown that the solubility products of the alkali metal complexes are two orders of magnitude higher than those for alkaline earth elements. The values of the solubility products decrease with increase in the ionic radius for both alkali and alkaline earth elements.


It is not just the evaluation of other cultures according to preconceptions originating in the standards and customs of one's own culture but also defines one's mental construct formed by the environment, which is reflected by the culture that one is living in. When colonial administrators, missionaries, and travellers were visiting the non-western world, they encountered the local communities and tried writing about "other cultures" because they were attracted by the cultural differences which were witnessing. These differences were understood in terms of a sense of inferiority and all their writings reflect their cultural hegemony. They tried to establish cultural superiority by adopting several intellectual strategies to study these communities. For instance, a study of youth dormitories brought out the presence of pre-marital sex and sexual laxity, which in turn brought out the loose sexual idea as opposed to the Christian idea of monogamy.


A COORDINATED PROGRAM of work for the blind in _The Netherlands is a comparatively recent development. It was not until after the Second World War that the work of various agencies and institutions was brought into focus through the establishment in 194 7 of the first central coordinating agency in the country. This in turn led to the creation in 1954 of a second centralized organization, this one devoted exclusively to the rehabilitation of the adult blind. A history of the rapidly developing field is essential .to an understanding of the problems involved and the work being done.


Abstract The impacts of single angular particles on ductile materials can result in large deformations and material chip separation, which cannot be effectively simulated using conventional mesh-based numerical methods. In this study, a novel particle-based mesh-free method called the Lagrangian gradient smoothing method (L-GSM) is first applied to simulate the dynamic process of single diamond-shaped particles impact on metallic surfaces. Based on the theory of L-GSM, a numerical model is established by incorporating the Johnson–Cook plasticity and failure models. Oxygen-free high-conductivity (OFHC) copper which is represented by a series of discrete particles, is selected as the material of the target block. Simulation results show that the L-GSM model can reproduce the typical erosion mechanisms such as cutting, micro-machining and ploughing. The large deformation of plastic craters and material removal are successfully simulated without using any additional techniques to handle the distorted domain. In addition, the computational accuracy and efficiency of the L-GSM are discussed by comparison with different mesh-free models. This study provides an effective numerical model with better accuracy and efficiency, helping to reveal the fundamental erosion mechanisms resulting from the impacts of angular particles.


Forested watersheds provide critically important ecosystem services, as sources of high quality water supply for drinking, agriculture, and industry. Additionally, tropical (and other) montane forests provide other benefits (services) such as wood products, recreation, and esthetic values. Advantages afforded by these environments are offset by episodic risks for communities located there as natural hazards such as floods, landslides, and wildfires, cause loss of life and damage or destroy infrastructure and crops. A basic understanding of rainfall and flood patterns by residents in these environments can mitigate these risks. However, climate change and global urbanization, particularly in regions of rapid economic growth, have resulted in much of this "organic" knowledge becoming less useful because of changes in storm magnitude and frequency, or lost, as newly arrived residents of megacities encroach on floodplains and mountain fronts. Moreover, the most likely occupants of these hazardous locations are often marginalized economically, which increases their vulnerability. In addition to the well-described services, ie. water, food, hydroelectric energy, wood products, carbon sequestration, maintenance of biodiversity, effective stewardship of river floodplains and upstream forests maintains a key ecosystem service: reduction of natural hazard and vulnerability. This benefit increases in importance as population continues to grow and climate continues to change. Examples of ecosystem services and natural hazards are presented for areas of Panama, Puerto Rico, and Venezuela, with discussion of benefits and risks. keywords: ecosystem services, climate change, water resources, natural hazards, tropics, Panama, Puerto Rico, Venezuela


The possibility of ion exchange technique with of IC-H Hypersep cartridge (Metrohm, Switzerland), sulfonated cation-exchange resins KU-2-8 (Russia) and Purolite C100 (UK) has been shown for ion separation of Mn (II), Fe(III), Cu(II) and Ni(II) ions from arsenite and arsenate ions. The conditions for ion-exchange removal of interfering cations in water when determining different arsenic(III, V) by stripping voltammetry have been optimized. The KU-2-8 cation-exchange resin based cartridge was found to be appropriate for use in the proposed sample preparation for water. The developed technique of analysis has been applied for the separated determination of inorganic arsenic forms in waters of different origin by anodic stripping voltammetry. The correctness of experimental results has been confirmed by the standard addition method.


With the rapid development of national economy,the demand for oil is growing rapidly in China.The oil price sees sharp volatility,which has become one of the important factors to restrict the social and economic development.On the basis of reviewing the evolution history of China's oil pricing mechanism,this paper discusses the drawback of China's oil pricing mechanism and corresponding strategies are proposed.


A Pediatric Dentist's greatest restorative challenge is the esthetic rehabilitation of a pre-schooler, who has lost anterior tooth/teeth subsequent to early childhood caries or extensive dental trauma. An anterior esthetic fixed or removable appliance is often the choice to replace lost tooth/teeth. Other important considerations replacing anterior teeth may include problems in speech and development of pernicious oral habits. The options presently available have their own limitations like poor patient compliance or retention of the appliance. Thus this paper discusses about modification of latest splint- it type of fiber reinforced composite (FRC) space maintainer with combination of orthodontic wires to aid in retention and longevity of the appliance.


Abstract The inhibitive and adsorption properties of ethanol extract of Hibiscus sabdariffa calyx were studied using gravimetric, gasometric, thermometric, and Fourier transform infrared methods of monitoring corrosion. The results obtained indicated that ethanol extract of Hibiscus sabdariffa calyx is a good adsorption inhibitor for the corrosion of mild steel in HCl solutions. The adsorption of the inhibitor on mild steel surface is spontaneous and supports the Langmuir adsorption model. From the calculated values of free energy of adsorption, the activation energy, and the variation of inhibition efficiency with temperature, it can be concluded that the initial mechanism for the adsorption of ethanol extract of Hibiscus sabdariffa calyx on mild steel surface is physical adsorption. Analysis of spectra obtained from the Fourier transform infrared spectrophotometer indicated that there is an interaction between iron in mild steel and the inhibitor.


The changing trends in the prevalence of childhood obesity, early puberty and menarche, and ethnoracial differences in the effect of BMI on the reproductive characteristics of young females around the world, warrants continuous evaluation. Hence, this study aims to investigate possible variations in the influence of BMI on the age at menarche as well as duration of menstrual cycle and menses in young girls in two urban areas in southern Nigeria. Participants (n = 52; median age = 20 years) were classified into 3 groups: normal, NM (n = 27; BMI = 21.0 ± 2.0 Kg/m2), overweight, OW (n = 14; BMI = 28.1 ± 1.2 Kg/m2) and obese, OB (n = 11; BMI = 31.5 ± 0.6 Kg/m2). BMI was calculated from the equation; BMI = weight, kg/height, m2. Cross-sectional data on menarche and menstrual cycle patterns were obtained through self-administered questionnaires. Data analysis showed a statistically significant difference in the BMI (p 0.05), the average duration of the menstrual cycle (NM = 27.3 ± 1.4 days; OW = 27.9 ± 0.6 days; OB = 29.4 ± 1.4 days) and menstrual bleeding (NM = 4.4 ± 0.6 days; OW = 4.4 ± 0.8 days; OB = 5.4 ± 0.9 days) differed significantly according to the BMI (p 0.05); and the average duration of the menstrual cycle tend to decrease with older menarcheal age, though this was not statistically significant (r = -0.02, 95% CI = -0.29 – 0.26, p> 0.05). Girls with higher BMI experience longer menstrual cycle and menses compared to their normal weight counterparts. The effect of BMI on age at menarche and the relationship between early onset of menarche and the duration of menstrual cycles and menses later in life may not be causal. Further investigations may resolve these differences in relation to the reproductive characteristics of young females.


A simulation study was undertaken to compare parametric L-moments and nonparametric approaches in flood frequency analysis. Data of various sample lengths were generated from a given generalized extreme value distribution and the quantiles estimated using the fixed-kernel nonparametric method and from a generalized extreme value distribution fitted by L-moments. From the resulting root-mean-square errors for various quantiles, it was concluded for unimodal distributions that nonparametric methods are preferable for large return period floods estimated from short (<30 years) samples while parametric methods are preferable in other circumstances. It was also pointed out that nonparametric methods are more suitable for mixed distributions. Key words: frequency analysis, L-moments, nonparametric methods, simulation.


This article explores the convergence between three pillars of influence – feminist security studies, civil society activism and policy decision-making – and its role in the adoption and implementation of United Nations Security Council Resolution (UNSCR) 1325. It argues that these three pillars, individually and collectively, have made important contributions to the debate and action on the gender and security agenda, but that they remain organically disconnected. Their convergence has the potential to achieve path-breaking results in the sphere of gender and security, whilst their divergence makes transformation unattainable. We show the disconnect in the application of UNSCR 1325 in Africa and argue that this is partly the reason why, despite enormous efforts, the gains realised in terms of gender equality in the peace and security arena have been negligible.


The purpose of this study was to examine Lazarus and Folkman's (1984) stress and coping theory in the context of workplace stress and coping with a focus on the influence of personal and cultural resources on cognitive appraisal, coping strategies, and the well-being of Chinese who are currently employed in professional occupations overseas. The data were collected from a volunteer sample of 228 overseas Chinese professionals (128 men, 100 women, M age = 32.6). Participants completed three sets of questionnaires over a six-week period (2 weeks apart). Specific variables of interest included cultural, social, and personal resources (Chinese collective values, perceived social support and work support, and general self-efficacy), situational appraisals (perceived situational control and self-efficacy), ways of coping (Engagement, Disengagement, and Collective strategies), and changes in short-term outcomes (job satisfaction, somatic symptoms, and depression symptoms). Items that assessed collective ways of coping were developed for this study. Significant differences were found between men and women in this sample. As such, path analysis (LISREL VIII) was used to test the hypothesized relationships in the model separately for men and women. Based on a zero-order correlation matrix, the results for the initial hypothesized path models indicated a moderate fitting model for men and an inadequate fitting model for women. However, modified models revealed a good model fit for both men and women, X 2 (29, N=128)=32.72, p=.29, Q=1.13, RMSR=.05, GFI=.96, and CFI=. 98, and X 2 (29, N=100)=44.10, p=.04, Q=1.52, GFI=.93, RMSR.07, and CFI=.92, respectively. The pattern of relationships (path coefficients) provide partial supports for the hypothesized model and Lazarus and Folkman's (1984) theoretical assumptions.


By using gray theory model, the problem with less data and poor information is easy to be solved. Thus, the grey theory and the reliability assessment method were connected to analyze the mechanism motion. At first, the concept and model of mechanism's grey movement reliability were presented. And then, from the limit state equations of a mechanism's moving function and kinematic accuracy, the gray reliability calculation formulas were deduced. Finally, combined with two examples the method was applied to the actual reliability analysis. The results show that the method is feasible and efficient, so it is practical to apply the grey reliability model in mechanism reliability analysis.


Photosynthesis has direct and significant effect on the growth and development of crop,and it is also the base of high yield.Therefore,it is significant to study the physiological change under different irrigation schedule to promote tomato production in the greenhouse.Through comparison between drip irrigation and traditional irrigation,the influence of drip irrigation schedule on physiological features and water using efficiency is studied.The results indicate that under the condition of drip irrigation,the peak of photosynthesis appears ahead,and the water utilizing rate of plants is improved;the stomatal conductance of tomato has significant correlation with net photosynthetic rate,transpiration and water utilizing rate;we can shorten the irrigation intervals while the irrigation amount is low to improve the water utilizing rate.


Conventional process of producing silicon based products uses large work-piece and it is difficult to attain high flatness of the finished surface. Thus it is not unusual to find it difficult to fine finish small area of planar surfaces and attain high degree of flatness on the finished surfaces. The manufacturing of silicon wafers in particular involves numerous grinding, lapping, and polishing processes of large diameter wafers employing expensive equipment in order to produce the required optical quality and damage-free surfaces. In the finishing of thin silicon chips for making IC chips especially, it is difficult to lap and/polish the substrate and obtain low surface integrity, surface finish and at the same time generate flat planar surfaces. Therefore the understanding of lapping process is very essential for economic manufacture and process improvement of thin silicon chips. A low cost lapping process has been developed, the process tried out on thin silicon chips that generated damage-free with a mirror-like surfaces of low roughness values and reasonably high degree of flatness.


Quantum entanglement is a phenomenon that has no classical counterpart; it is not only difficult to learn but also difficult to teach. It is often an omitted or underrepresented topic in the syllabus of an introductory quantum mechanics or modern physics course. Nearly 40 years ago Mermin published a thought experiment to analyze a device consisting of a transmitter and two receivers. The receivers each had a three-position switch and two lights, one red and one green. Analysis of the operation of the device follows the predictions of quantum mechanics but only simple mathematics is employed to demonstrate the peculiar nature of quantum entanglement. A few years later he reintroduced his quantum device to a more general audience in a Physics Today article and provided another interesting interpretation. In the current paper, we make use of the recently published work in quantum information theory by Candela to have students write code to simulate the operation of the device in that article. Analysis of the device has significant pedagogical value—a fact recognized by Feynman—and simulation of its operation provides students a unique window into quantum mechanics without prior knowledge of the theory.


Exposing massive parallelism on 3D unstructured meshes computation with efficient load balancing and minimal synchronizations is challenging. Current approaches relying on domain decomposition and mesh coloring struggle to scale with the increasing number of cores per nodes, especially with new many-core processors. In this paper, we propose an hybrid approach using domain decomposition to exploit distributed memory parallelism, Divide-and-Conquer, D&C, to exploit shared memory parallelism and improve locality, and mesh coloring at core level to exploit vectors. It illustrates a new trade-off for many-cores between structuredness, memory locality, and vectorization. We evaluate our approach on the finite element matrix assembly of an industrial fluid dynamic code developed by Dassault Aviation. We compare our D&C approach to domain decomposition and to mesh coloring. D&C achieves a high parallel efficiency, a good data locality as well as an improved bandwidth usage. It competes on current nodes with the optimized pure MPI version with a minimum 10% speed-up. D&C shows an impressive 319x strong scaling on 512 cores (32 nodes) with only 2000 vertices per core. Finally, the Intel Xeon Phi version has a performance similar to 10 Intel E5-2665 Xeon Sandy Bridge cores and 95% parallel efficiency on the 60 physical cores. Running on 4 Xeon Phi (240 cores), D&C has 92% efficiency on the physical cores and performance similar to 33 Intel E5-2665 Xeon Sandy Bridge cores.


Public transport is the cheapest and has therefore, always been popular with the masses. The advancement in transport system has been increasing in day-to-day life. The transport plays a vital role in individuals life, in making it efficient we are introducing an android application. The android application has the bus ticket system using QR reader. The android mobile has a great part in human life, it helps the people to be stay connected with web. In this project, we are proposing QR reader for bus ticketing system. The QR code (Quick Response code) becomes popular outside the automotive industry due to its fast readability and greater storage capacity compared to standard UPC barcodes. The proposed system provides web application as well as android application for the passengers to buy their tickets online. During the travel time, we can get the ticket by entering their location details and make payment. Message alert will be notified to the passenger. By this application, we can minimize the usage of paper (Tickets) and there will not be any problem in getting change. KeywordsSmart bus ticket, QR code, android bus ticket, web application;


Islamist terrorists attack Brussels and kill many people, in a manner similar to the Paris attacks – similar scenarios in different European cities. Do extreme right-wing nationalists like Le Pen…


The utility model discloses a multi-functional bowl-clamping and peeling device which comprises a handle, a hanging opening, a bowl-clamping device and a peeling device, wherein the upper end of the handle is heart-shaped, the hanging opening is arranged on the handle, the bowl-clamping device is fixed at the lower end of the handle, and the peeling device is arranged on the bowl-clamping device. The bowl-clamping device is a tool frequently used in the kitchen in life and is suitable for bowls and dishes with different sizes, and the bottom of the bowl-clamping device is arranged into the peeling device, thereby adding functions and being easy to use. The peeling device is a small article and not easy to find in use, and the peeling device can be easily found when being combined with the bowl-clamping device.


We find the Small Business Administration's disaster-relief home loan program denies significantly more loans in areas with larger shares of minorities, subprime borrowers, and higher income inequality. We find that risk-insensitive loan pricing -- a feature present in many regulated and government-run lending programs -- is a primary driver of these disparities in access to credit. The differences in denial rates are disproportionately high compared to private-market lending and government-insured risk-sensitive loan pricing programs. Thus, despite ensuring "fair" prices, the use of risk-insensitive pricing may lead to "unfair" access to credit.


Medical imaging captures visual representation of human body's structural and functional aspects like tissues, bones, blood flow etc. for clinical analysis and medical intervention. Optical Imaging, X-ray, Computer tomography, Magnetic Resonance Imaging (MRI), Ultrasound etc. are common medical imaging techniques used by physicians. Among them ultrasound is the most widely used imaging technique due to its cost effectiveness and human health friendly characteristic. But ultrasound images are inherently corrupted with speckle noise and thus makes physician's interpretation complex and time-consuming. Therefore, in medical image analysis image denoising has more clinical value since it helps the physicians to reach correct, reliable and speedy diagnosis by mitigating noise from the image. Image denoising also facilitate image segmentation, image fusion, object detection and target recognition. Computer-aided image denoising and image enhancement techniques helps to improve efficiency and accuracy of physician's interpretation. This research work focused on the development of reliable image denoising and enhancement techniques for echocardiographic images. It aimed to denoise an echocardiographic image without introducing noise distortion and loss of information. Fractional calculus has been used to efficiently mitigate noise of various levels from the echocardiographic image. Also rough set theory and fuzzy logic have been used to draw boundaries between image regions. These concepts helped to handle uncertainty caused by the speckle noise. Three image denoising methods have been proposed in thesis. First proposed denoising methodology performs image denoising in two stages. Stage-1 applies weighted fuzzy mean filter and stage-2 convolves every pixel of the image with a fractional integration filter. Second proposed approach intelligently selects appropriate filter for every image region. Fractional order differintegral filter is proposed in third image denoising methodology. All three proposed denoising schemes not only preserve details in the denoised image but also efficiently reduce noise. Image Enhancement further improves the visual quality of an image. This research also proposes two echocardiographic image enhancement schemes to effectively utilize gradient magnitude and eigenvalue hessian matrix calculations and fractional order derivative concept. Real echocardiographic b-mode images and standard images artificially corrupted with speckle noise have been considered in simulations for this research. Visual and quantitative analysis of simulation results presents significant improvement by the proposed schemes as compared to state-of-the art image denoising and image enhancement techniques.


Background: The prognostic outcomes of endovascular therapy (EVT) for isolated infrapopliteal lesions remain to be adequately studied. Objectives: We investigated and risk-stratified long-term prog...


Aim To construct a CHO cell expression vector carrying coamplification gene. Methods Based on the mammalian expression vector pCI neo, a new mammalian expression vector pCdhfrl was constructed with dihydrofolate reductase(dhfr) gene as selection and coamplification marker. To evaluate its applied value, the enhanced green fluorescent protein(EGFP) gene was subcloned into pCdhfr l and the recombinant expression plasmid pFP was transfected into Chinese hamster ovary(CHO) cells mediated via liposome. Results After one cycle of amplification by methotrexate(Mtx), the CHO cell colonies stably expressed green fluorescent protein. Conclusion A model for the construction of engineered CHO cell line producing recombinant protein with CHO/DHFR system is established.


Correspondence Address: (57) ABSTRACT STRIKER, STRIKER & STENBY 103 EAST NECK ROAD A knitted garment (10) for the Support and/or compression HUNTINGTON, NY 11743 (US) of parts of the body and/or for compression therapy is knitted in the shape of a tube (11, 12, 13, 14, 15, 16) using (21) Appl. No.: 11/157,008 at least one elastic knitting thread and at least one elastic weft thread, at least in Sections, on a flat bed knitting (22) Filed: Jun. 20, 2005 machine.


This paper presents an all-digital current-sensorless multi-mode DC-DC converter for portable applications. All-digital load current detector, operation mode detector and multi-mode controller are implemented. The multi-mode controller can seamlessly change modes between pulse frequency modulation (PFM) and pulse width modulation (PWM) with the aid of load current detector and operation mode detector. The cooperation of PWM and PFM can maintain good output voltage regulation and light-load efficiency over wide load range. The digital controller, power MOSFET and driver are fabricated in TSMC 90-nm standard CMOS process. The experimental results show that the proposed architecture can achieve high efficiency over a wide load range.


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Twelve years ago the CFPC Board decided to combine its 2 annual conferences—the springtime scientific assembly and fall's Section of Teachers' meeting—into a single conference called Family Medicine Forum (FMF). The goal was to create a meeting where family doctors from


Electrodes containing only electroactive material processed to relatively large thicknesses (often greater than 500 microns) can have high energy density at the cell level due to the high loading of electroactive material. The specific all electroactive lithium-ion material electrodes in this work undergo a mild thermal treatment and are referred to as sintered electrodes. While in general the great thickness results in long ion diffusion paths which limits rate capability of sintered electrode cells, the lack of inactive additives provides a relative advantage in effective ionic transport properties.
 In this talk, recent improvements in sintered electrode batteries will be discussed. In particular, incorporation of new materials with increased gravimetric and more importantly volumetric energy density will be described. In some cases, the alternative materials have lower electronic conductivity than previously used electroactive materials for sintered electrodes, and processing strategies for alleviating electronic conductivity limitations will be discussed. Incorporation of modified materials and processing results in very high energy density small form factor battery cells.


According to the current situation of water resources in cities in Henan Province, this paper establishes the index system based on the principle of "allocating the water resources reasonably for the development of agriculture, population, and industries". The water resources carrying capacity of cities in Henan Province from 2010 to 2020 was evaluated by the improved matter-element extension model along with improved entropy weight method and variation coeffi- cient method, and suggestions were put forward for "constraining towns by water resources" from the perspective of spatial layout. According to the results: (1) the water resources carrying capacity of each city developed in a sound manner. 14 cities in Henan Provinces, includ ing Zhengzhou, Kaifeng, Luoyang, Pingdingshan, Anyang, Hebi, Xinxiang, Jiaozuo, Puyang, Xuchang, Sanmenxia, Nanyang, Xinyang and Jiyuan showed a positive trajectory during the study period, Luohe showed the best performance, Zhoukou, Zhumadian had the worst per - formance and Shangqiu had a complicated performance. (2) In terms of the time dimension, the overall performed of water resources carrying capacity showed an increasing trend year by year. The results of the study can provide theoretical support for the further sustainable development of water resources in cities of Henan Province.


The ability to effectively cite information sources is key to both student avoidance of plagiarism and the ongoing scholarly conversation. Previous research and experience indicated that students had significant trouble distinguishing and citing various information formats when viewed online; items are often cited as websites, and citations are incomplete or contain erroneous and extraneous information. The authors investigated the prevalence of these problems at their university, seeking out common patterns in the data to determine what, if any, information literacy objectives may be useful for future studies and instructional practice.


A reply to a recently published report by Coopers & Lybrand, very critical of the state of marketing management in the United Kingdom.


Steinhaus' lattice points problem addresses the question of whether it is possible to cover exactly n lattice points on the plane with an open ball for every fixed nonnegative integer n. This paper includes a theorem which can be used to solve the general problem of covering elements of so-called quasi-finite sets in Hilbert spaces. Some applications of this theorem are considered.


Introduction. The boundaries between MDS and AML are still a matter of debate. In the 2001 WHO Classification, the myeloblast count distinguishing AML and MDS was lowered from 30% to 20% of the bone marrow (BM) cells or peripheral blood (PB) leukocytes. It was justified on the basis that treating patients with 20-29% BM blasts with intensive chemotherapy showed a similar outcome to those with > 30% BM blasts.
 However, the better knowledge of the biology of both diseases is showing that in several cases AML and high risk MDS share identical genetic profiles, as it is well known in AML with myelodysplasia- related changes (AML-MRC). Currently there are new therapeutic options, less toxic, and suitable for elderly people.The threshold of 20% BM blast is artificial, but it is still the main criterion used in clinical trials and also in real life to discriminate patients that probably belong to the spectrum of the same biological entity. Treatment of patients with MDS or AML is widely based in this relatively arbitrary condition.
 Objective: To study if the threshold of 20% bone marrow blasts, distinguishing MDS with excess of blasts type 2 (MDS EB 2) and AML, is reproducible among different observers.
 Methods. 120 bone marrow samples from patients previously diagnosed with MDS-EB-2, AML or therapy-related myeloid neoplasms (t-MN) according to 2016 WHO classification were included. The diagnosis of MDS required cytogenetics and/or FISH, and the cases with AML should have been classified following the 2017 ELN recommendations, regarding immunophenotyping, cytogenetics and molecular biology. The design of the study was established to include cases with <40% BM blasts, WBC <25x109/L and less than 20% myeloblasts in peripheral blood. The proportion of samples from each category was not predefined. Specimens were collected from 12 hospitals and were evaluated by 12 morphologists. Each observer evaluated 20 samples, and each sample was analyzed independently by two morphologists. The second observer was blinded to the clinical and laboratory data, except for the peripheral blood (PB) counts. The interobserver concordance was evaluated using the Cohen kappa test.
 Results. Finally 116/120 samples were considered suitable for the study. Regarding 2016 WHO categories, 55 cases showed MDS EB-2, 44 AML-MRC, 8 t-MN, 4 AML- NOS, 2 NPM1-mutated AML, 2 RUNX1-RUNX1T1 AML, 1 BCR-ABL1+ AML. Next generation sequencing was performed in 79 cases. Discordance was observed in 34/116 cases (29.3%). 14 cases with MDS-EB2 (1 NPM1+) were classified as AML-MRC by the second observer, 16 AML cases as MDS EB-2, 3 MDS EB-2 as MDS- EB1 and 1 AML as MDS- EB1. The genetic and /or molecular profile of the discordant cases was heterogeneous. Regarding the threshold of 20% BM blasts, discrepancies were 31/116 (26.7%, I Kappa test = 0.46, moderate agreement). The agreement between MDS-EB-2 and AML-MRC, with discordance in 28/98 cases (28.6%), was moderate-fair (Kappa test= 0.42).
 Conclusion. The threshold of 20% BM blasts did not accurately separate AML from MDS EB-2. Particularly less concordance was seen for AML-MRC. Incorporation of genetic and molecular characteristics to the morphologic diagnosis is needed to optimize the definition of both entities.
 Acknowledgment: Angel Cedillo, Secretaría Técnica AMHH.

 Font Lopez: GILEAD: Membership on an entity's Board of Directors or advisory committees; CELGENE-BMS: Consultancy, Membership on an entity's Board of Directors or advisory committees; Pfizer: Membership on an entity's Board of Directors or advisory committees. Loscertales: Janssen, Abbvie, Astra-Zeneca, Beigene, Roche, Gilead: Consultancy; Janssen, Abbvie, Roche, Gilead: Speakers Bureau. Cedena: Janssen, Celgene and Abbvie: Honoraria.


Gestural interface has been the subject of research for more than 40 years. The implementation of a novel intuitive and adaptive manipulation scheme is proposed by developing a human-machine communication interface between the Leap Motion controller and the wheel chair. In addition, an algorithm is developed to allow an optimum mapping between the user hand movement, tracked by the Leap Motion controller, and the wheel chair. The system should allow for a more natural human-computer interaction and a smooth manipulation of the wheel chair, by constantly adapting to the user hand tremor or shake. The sensor detects motions and moves the wheelchair accordingly. It will track the movement of the fingers and hands in order to identify the gesture, and then the motors will perform the required action using Arduino. The implementation would specially enhance the quality of living, especially for people with lower limb problems, and would support them in performing some of the essential Activities of Daily Living "ADLs".


Compact structure of the multi-device of the invention, the first sensor, second sensor and a three sensor arrangement of the sensor device integrated into a single device of the third sensor, the first sensor 3 for detecting a three-axis acceleration dimensional and the acceleration sensor, the second sensor and the third sensor, and a sensor for the single physical quantity measuring process for jungangji portion of the first sensor, a first-axis sensor element and a second-axis sensor element of said first sensor, each is composed of a piezo resistance the two pairs are arranged to face to the center of the jungangji portion and to the second sensor and the element is characterized by a composed of a piezo resistance of the two pairs arranged see, facing each of the third sensor. Micro Multi Device (MMD), 3-dimensional acceleration sensor, a pressure sensor, humidity sensor, temperature sensor, SOI, Deep RIE, Novel Wheatstone Bridge, Silicon Devices, Glass


The purpose of this study was to investigate the relationship between the pre-operative clinical course of patients with rheumatic heart disease, who underwent commissurotomy of the mitral valve, and the occurrence of Aqchoff bodies in the left atrial appendage removed at the time of operation. With the development of surgical intervention in rheumatic heart disease, considerable discussion has arisen concerning the significance of the Aschoff bodies frequently found in atrial appendages removed at operation.27 The patients selected for mitral commissurotomy were, in the great majority, considered free of rheumatic activity at the time of operation, often after extensive and careful clinical emination. It of bodies great 74 per cent.4 bodies generally electrocardiographic elevation of the anti-streptolysin 0 titer, rapid erythrocyte sedimentation rate, the appearance of C-reactive protein,514'18'23 of Aschoff bodies in atrial appendages discrepancies students rheumatic heart con-clude that atrial Aschoff bodies are not indicative rheumatic activ-This


A colleague, who had read this book before me, summarised it succinctly: 'It shows how we (women) now have political citizenship, but not yet economic citizenship'. True, and alas, the political kingdom does not necessarily provide a comfortable home for women whose needs are often also in the economic domain. But this book also pays attention to other serious and urgent issues facing South African women: HIV/AIDS and violence against women (and children), to name but two (note that both have explicit or implicit economic implications). And even political citizenship is still problematic when one looks at representation and decision-making participation. In fact, this book deals with a range of 'citizenships': political, economic, legal, cultural and also, importantly, the sexual nature of citizenship. Gouws and her co-workers are mainly concerned with theorising issues of citizenship, using empirical evidence as illustration of their concerns. The complexities and the paradox between a progressive legal framework encouraging gender equality, on the one hand, and, on the other hand, continuing adverse conditions (poverty, HIV/AIDS and gender-based violence) impacting most heavily on women and girl children, are captured in the theorisation offered in this book. It is impossible in a book of this nature to give due credit to each contribution, which is a pity. We have here a collection of important and thought-provoking essays which raise and deal with issues that lie at the heart of South African society. The book is divided into five parts: an overview of the making of gendered political subjects in post-apartheid South Africa, a deconstruction of the discourse of citizenship, an interrogation of legal boundaries, citizenship as agency and, in Section V, two chapters on 'sexual' citizenship. The inclusion of Conway's chapter on 'Masculinity, Citizenship and Political Objection to Military Service in Apartheid South Africa' jars with other contributions for the simple reason that the book's sub-title refers to 'contemporary' South Africa and the relevance of this chapter vis-à-vis the other contributions is not made explicit. To some extent the same could be said of Fester's chapter on 'motherism' and the way in which such private sphere concerns evolve into a consciousness that engages the public sphere. Her case study is women's grassroots organisations in the Western Cape during the 1980s. However, she captures part of the development of the women's movement in this country and it was this movement that contributed in a powerful way to post-apartheid ideas and processes aimed at the inclusion of women in all spheres of life. Fester's contribution ties in well with that of Hassim on 'Nationalism Displaced: Citizenship Discourses in the Transition'. Hassim traces the Politikon, (August 2006), 33(2), 251–257


Based on covariance constraint control theory and expert system, the fault prediction problem inner the dynamic building-up system is researched. First of all, the observed state values of fault-spot at the sub-systems are extracted in accordance with the running circumstances of system on line, then we have defined and analyzed the parameter structure of the average observed state values,error and error-sum correspondent to the fault point. Secondly, based on the defined award theory of Fault Prediction and using the state error-sum constraint values got by adding-power algorithm at fault-point, a sequential graph of FP is designed. Finally, a new fault prediction algorithm is presented. The theory analysis indicates that the presented algorithm has obvious advantage compared with the traditional fault diagnosis and fault predict methods.


The term Gongnon( 公論) used in modern Korean can be translated into 'public opinion' in English. However, the traditional concept of Gongnon in Joseon Dynasty meant 'the opinion approved by everyone because it observes the law of nature and accords with the human nature'. This study analyzes the concept of Gongnon in Hansung Sunbo, Hansung Jubo, and The Independent News (1896), applying the conceptual historical approach in order to trace the process of de-territorialization of Confucian concept of Gongnon to its modern concept. As a result, the concept of Gongnon is explained and justified by the modern media based on the Confucian concept of Gong (公). This concept, like the International Gongnon, also understood and imagined international relations based on Confucian ethos. Finally, The concept of Gongnon justified its goal by citing Confucian ideas and expressions in pursuit of modern nations, and relocated the Semantic field of concept of Gongnon as well.


Protein kinase C δ (PKC δ) is tyrosine-phosphorylated and catalytically inactive in mouse keratinocytes transformed by a ras oncogene. In several other model systems, Src kinases are upstream regulators of PKC δ. To examine this relationship in epidermal carcinogenesis,v-ras transformed mouse keratinocytes were treated with a selective Src kinase inhibitor (PD 173958). PD 173958 decreased autophosphorylation of Src, Fyn, and Lyn kinases and prevented tyrosine phosphorylation of the Src kinase substrate p120. PD 173958 also prevented PKC δ tyrosine phosphorylation and activated PKC δ as detected by membrane translocation. Expression of keratinocyte differentiation markers increased in PD 173958-treatedv-ras-keratinocytes, and fluid-filled domes emerged, indicative of tight junction formation. Antisense PKC δ or bryostatin 1 inhibited dome formation, while overexpression of PKC δ in the presence of PD 173958 enhanced the formation of domes. Plasmids encoding phenylalanine mutants of PKC δ tyrosine residues 64 and 565 induced domes in the absence of PD 173958, while phenylalanine mutants of tyrosine residues 52, 155, and 187 were inactive. Thus, Src kinase mediated post-translational modification of PKC δ on specific tyrosine residues in ras-transformed mouse keratinocytes inactivates PKC δ and contributes to alterations in the differentiated phenotype and tight junction formation associated with neoplasia.


Every winter, hospital managers hope that patient admission rates are not exceptional. When admission rates rise, some managers ask GPs to request fewer admissions to ease the secondary care load. Is this feasible? Are admissions by GPs avoidable and / or unnecessary? For an ill patient, is nursing home admission an alternative to hospital? This study assesses such issues on the basis of one locality's experience, and offers opinions and provisional lessons from the findings.


Abstract In recent years, naval shipbuilding in the UK has been given a significant boost with the Type 45 destroyer programme and the Queen Elizabeth Class (QEC) aircraft carrier programme. Both these programmes raised a number of new issues with regard to the rolled materials used in their construction. The Type 45 programme focused heavily on the use of higher strength steel to reduce weight, which in itself generated other challenges from the use of thin plate. Significant issues about residual stresses became evident through the construction phase and also through some joint academic studies. The QEC programme utilised some of the material concepts developed on Type 45, but included the need to use a higher strength steel on the flight deck and the hanger deck. Specific areas of the vessels are subject to through thickness tensile stresses and almost 3000 t of plate are Z grade. Within that, a small proportion is required to meet a 60°C toughness requirement, in certain areas. This has led on to a more wide ranging review of currently available materials and their potential application within naval shipbuilding. The use of still higher strength steels has been considered in a number of thickness ranges and their potential for blast resistance is being assessed.


The opening is a basis for development and evolution of a slope system which is composed of a lot of small systems. In order to study the opening of slope evolution, a concept of opening is put forward and its theoretical formula is presented. The relationship between the opening degree (P) and the entropy is discussed theoretically.


In this paper, t wo novel ult ra wideband (UW B) minimized antennas based on the composite right/left-handed transmission lines (CRLH-TLs) structures are designed. The proposed antennas are presented with best in size, bandwidth and radiation patterns. To realize characteristics of the antennas ψ-shaped gaps print into radiation patches are used. Overall sizes of the CRLH antennas are 24.8mm by 9.5mm by 1.6mm and 37.2mm by 9.25mm by 1.6mm, respectively. These antennas can cover the frequencies bandwidths from 2.8-11.8GHz and fro m 2.1-11.7GHz for VSWR < 2. The antennas highest gains and maximu m rad iation efficiencies are 7.71d Bi and 54.93% at operation frequency 11GHz for first antenna and 7.02d Bi at f=11.7GHz and 61% at f=10GHZ for second antenna, respectively.


Anaerobic treatability of foul condensate discharged from the evaporation-enrichment process of black liquor from a paper and pulp mill was investigated by using batch and a small scale UASB reactors. The foul condensate used in the experiment was anaerobically biodegraded and the removal rate of CODCr in anaerobic treatment was expressed as the first-order reaction with respect to the biodegradable CODCr, and the reaction rate constant was 3-5 X 10-5l·mg-1·h-1. The CODCr removal efficiency in an UASB reactor was as high as 70% when the volumetric CODCr loading was lower than 10kg·m3·d-1. Methane productivity of the condensate was 0.16-0.24 Nm3·kg-1-CODCr.


Survey of methylene orange wastewater treatment by activated carbon material prepared from macadamia husk with chemical activator H3PO4 shows that coal with the best methylene orange color treatment is achieved Optimal conditions such as pH = 5, coal dose 0.9 g/L and time 120 minutes. The results show that it is applicable to color wastewater treatment and the results are similar to other research results.


The presentation of travel time information to drivers is one of the important roles of information systems concerned with road traffic. This paper proposes a method for predicting the travel time in urban districts using travel time data from the small sections which make up a route. The forecasting model consists of past time series data on the travel times in the small sections. The travel time for the route in the near future and its accuracy are estimated by using a state equation of the forecasting model. The validity of the method is verified using real data. Validation showed that the prediction error was approximately 2.5 minutes. Generally, for 50 minutes of travel time, it is desirable that the prediction error be within 5 minutes. Therefore, this result appears satisfactory for practical use. © 2009 Wiley Periodicals, Inc. Electron Comm Jpn, 92(7): 1–11, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecj.10089


The ASPEN PLUS commercial simulation software has been used to develop a process model for a conceptual process to convert municipal solid waste (MSW) to hydrogen. The process consists of hydrothermal treatment of the MSW in water to create a slurry suitable as feedstock for an oxygen blown Texaco gasifier. A method of reducing the complicated MSW feed material to a manageable set of components is outlined along with a framework for modeling the stoichiometric changes associated with the hydrothermal treatment process. Model results indicate that 0.672 kmol/s of hydrogen can be produced from the processing of 30 kg/s (2600 tonne/day) of raw MSW. A number of variations on the basic processing parameters are explored and indicate that there is a clear incentive to reduce the inert fraction in the processed slurry feed and that cofeeding a low value heavy oil may be economically attractive.


AIM To study the proper rate of bitter apricot seed to platycodon root,in the treatment of relieving cough and expelling phlegm.METHODS Cough models were made by strong agua stimulation in mouse and citric acid stimulation in guinea pig,cough latency and cough times were recorded respectively.Model for expelling phlegm,phenol red solution was injected intraperitoneally to mice,and the spectroplcoto metric measurement of the trachea leachate was carried out.RESULTS Bitter apricot seed,platycodon root,and their different combinations all significantly reduced the cough times,prolonged the coughing latent period,and increased the trachea excretion.CONCLUSION The effect of relieving cough and expelling phlegm is the strongest when the compatibility ratio of bitter apricot seed and platycodon root is 1∶ 1 and 1∶ 2 respectively.


Background. Dyskeratosis congenita (DC) is a telomere biology disorder with a high risk of bone marrow failure, cancer, pulmonary and liver disease. Mutation in multiple telomere related genes including DKC1, TINF2, RTEL1, TERC, TERT, WRAP53, CTC1, NOP10, NHP2 and TPP1 have been reported. Patients with mutations in several DC genes (e.g. heterozygous TINF2, hemizygous DKC1 and biallelic RTEL1 mutations) typically tend to have a particularly serious disease with severe bone marrow failure (SBMF) at a young age, non-hematological manifestations and very short telomeres. Currently, allogeneic hematopoietic stem cell transplantation (HSCT) is the only available curative treatment for bone marrow failure and leukemia in DC patients. Relatively few case series of patients with DC undergoing HSCT have been reported, which generally suggested a poor outcome. The present study aimed to characterize the outcome of HSCT in a Canadian cohort of patients with DC and determine potential relationships between outcome and genotype.
 Methods. The Canadian Inherited Marrow Failure Registry (CIMFR) is a multicenter registry that includes tertiary centers that care for IBMFS patients across all Canadian provinces. Patients with DC who had been enrolled in CIMFR and underwent HSCT between January 2001 and December 2019 were included. Data were extracted from the CIMFR database.
 Results. Among 35 patients with DC enrolled in the CIMFR, 11 underwent HSCT. Seven patients were male. Median age at presentation, diagnosis and HSCT was 2.1 years (range: 0 to 9.13s), 5.5 years (range: 1.94 to 35.25), and 7.0 years (range; 0.5-37), respectively. The diagnosis of 3 patients was made after HSCT. Median follow up time from HSCT was 5.89 years (range; 0.2-14.0 years). Among transplanted patients, five had TINF2 mutations, two had RTEL1 mutations, and one patient had DKC1 mutation. Eight patients underwent HSCT for severe bone marrow failure, and three patients for single or multilneage cytopenia. All patients had normal bone marrow karyotype before HSCT.
 All patients had a full matched donor; two were related and nine were unrelated. Ten patients received reduced-intensity conditioning, and one received myeloablative conditioning.
 Two patients experienced engraftment failure and underwent a second HSCT. Five years and ten years overall survival after HSCT were 90.9% (95% CI 73.9-100%) and 80% (95% CI 27.2- 97.5%), respectively; however, complications and deaths started appearing thereafter, mainly in patients with TINF2 mutation. All five patients with TINF2 mutation died, and other patients were alive. The causes of death were: 1) pulmonary fibrosis (N=2), 2) gastrointestinal bleeding (N=2), and 3) EBV infection (N=1). Two patients were diagnosed with pulmonary fibrosis after 8 and 11 years from HSCT and died 13.7 and 14 years post-transplant. Two patients had gastrointestinal bleeding after 3.9 years and 4.8 years from HSCT and died 6.6 and 5.7 years post-transplant. Of the patients with GI bleeding, both had hepatic fibrosis and one had pulmonary fibrosis.
 Summary: In this series, most patients with DC had resolution of the bone marrow failure and relatively good quality of life in the first few years post HSCT. However, longer outcome in the patients with TINF2 mutation was dismal because of DC-related complications, especially pulmonary fibrosis and gastrointestinal bleeding. Effective therapies to prevent these complications are critically needed. Additional reports about HSCT outcome of patients with DC are necessary to characterize HSCT in patients with other genetic groups and to replicate the above results in TINF2 patients.

 No relevant conflicts of interest to declare.


An Empirical Biomass Model for the Japanese sardine, Sardinops melanostictus, was developed on the basis of the relationship between February sea surface temperature (SST) in the Kuroshio Extension (30–35°N, 145–180°E) and the mortality coefficient during the period from egg to age 1, observed in 1979–94, to examine the long-term variation of biomass. The periods of the good and bad catch, the year of the biomass peak, and the speed of the biomass decline in the period from 1957 to 1994 were successfully reproduced, except for the biomass increase in the early 1970s. When the model also included with a density-dependent effect, the whole history of the observed catch during 1957–94 was almost perfectly reproduced. These results suggest that the environment in the Kuroshio Extension region, represented by winter–spring SST, is regarded as a leading factor for determining fluctuations of the sardine biomass in the long term, and that the density effect has a secondary contribution.


ABSTRACT Total, non-volatile free fatty acids (FFA) content was determined in hake muscle during fkh storage in ice. FFA increased linearly in every season according to freshness loss as determined by sensory scoring. FFA deter- mination is proposed as a valuable alternative to sensory scoring in deter- mining fkh deterioration in ice. Key wordr: Hake, Merluccius hubbsi, freshness index, ice storage, free fatty acids. 1 INTRODUCTION Hake freshness has been traditionally evaluated through sensory assessments.' Recent developments to replace sensory scoring by physical or chemical methods have been introduced.* These methods, however, do not provide enough sen- sitivity in the first 5-10 days of storage and the detected changes are too small to follow the storage life of hake stored in ice. A good improvement seemed to be the viscosity determination of soluble muscle protein extracts taken from hake stored in This parameter, however, is subject to non-linear seasonal variation^.^


The problem about radar maintenance in army mostly relies on the factory's support.The timeliness and effectiveness cannot satisfy the need of force.The design uses the artificial intelligence technology for building the fault diagnosis Expert System based on CLIPS,make the general maintenance personnel could use and master the diagnosis technology.That has great practical significance for improving the integrated supporting capability and increasing battle effectiveness of radar.


Vision-based grasping for humanoid robots is a challenging problem due to a multitude of factors. First, humanoid robots use an "eye-to-hand" kinematics configuration that, on the contrary to the more common "eye-in-hand" configuration, demands a precise estimate of the position of the robot's hand. Second, humanoid robots have a long kinematic chain from the eyes to the hands, prone to accumulate the calibration errors of the kinematics model, which offsets the measured hand-to-object relative pose from the real one. In this paper, we propose a method able to solve these two issues jointly. A robust pose estimation of the robot's hand is achieved via a 3D model-based stereo-vision algorithm, using an edge-based distance transform metric and synthetically generated images of a robot's arm-hand internal computer-graphics model (kinematics and appearance). Then, a particle-based optimization method adapts on-line the robot's internal model to match the real and the synthetically generated images, effectively compensating the kinematics calibration errors. We evaluate the proposed approach using a position-based visual-servoing method on the iCub robot, showing the importance of the continuous visual feedback in humanoid grasping tasks.


In this paper, third generation SiC fiber material irradiated with the 410 MeV energy of [Formula: see text] ion at 173 K was analyzed by Raman spectroscopy, X-ray diffraction (XRD) and transmission electron microscope (TEM). Raman spectroscopy, TEM and XRD data show modifications in the local structure of irradiated SiC fibers. Although highly disordered SiC grains were observed in appearance, no evidence of amorphization was found. After the Sn ions irradiation and XRD, two diffraction peaks disappeared, which showed that the rich Si and C could be further combined in [Formula: see text] ions/cm2 dose irradiation condition. This result mainly explains the electron damage and the nuclear damage process in SiC fibers, leading to the recombination or migration of defects.


Disclosed are a mobile terminal switching antenna and a switching method therefor. The mobile terminal switching antenna comprises an antenna, a radio frequency module, a baseband chip, a divider module, a noise insulating module, a DC blocking module, a one-way connection module and an antenna matching module. The baseband chip is connected to the antenna through the radio frequency module; the baseband chip is connected to the antenna sequentially through the divider module, the noise insulating module and the DC blocking module; the baseband chip is further grounded sequentially through the divider module, the noise insulating module, the one-way connection module and the antenna matching module; and the baseband chip does not transmit and transmits control signals to the antenna so as to switch operating states of the antenna, thus correspondingly changing receivable frequency ranges of the antenna, greatly improving receiving and transmitting performance of the mobile terminal antenna, and bringing great convenience to users.


Calcium channel blockers are widely used in cardiovascular diseases. Besides L‐type channels, T‐ and P/Q‐type calcium channels are involved in the contraction of human renal blood vessels. It was hypothesized that T‐ and P/Q‐type channels are involved in the contraction of human brain and mammary blood vessels.


This study employs an eclectic model for the analysis of offensive language features in Penguins of Madagascar (2014), American children's movie. The model adopted involves a sociolinguistic perspective based on Tagliamonte's (2012) social variables and Ho lms' (2013) social factors and social dimensions. Other perspectives in the model adopted for the study include a semantic level, that focuses on connotation, denotation and euphemism as proposed by Allan & Burridge (2006), a pragmatic level, including deixis, and politeness according to Yule (2010), and a semiotic level, that revolves around visual representation of social actors network suggested by Van leeuwen (2008), facial expression by Ekman and Priesen (2003) and color by Kress& Van leeuwen (2002). The analysis yields the conclusion that there are no age, social class or gender differences in employing offensive words such as name-calling, verbal violence and insults that are used to express negative and aggressive emotions as well as to show intimacy, humor, solidarity and joy. These words are also used to discredit the counterparts and to provoke confrontations between distant participants.


Quite recently, we reported the synthesis of supercharged polycations bearing pH-insensitive double-charged repeat units with either three or five methylene groups in the space between charges. The developed approach is based on the quaternization of the parent poly(4-vinylpyridine) with different alkylating agents, providing the possibility to perform the modification as a one-step reaction, which occurs in mild conditions with a controllable degree of conversion. In the present work, we used the above approach for preparing and investigating supercharged polyplexes (polyelectrolyte complexes of nucleic acids), in particular to elucidate the reason for the key feature, i.e., the clearly defined stability of the polyplexes formed by supercharged polyamines. The main findings of the experimental study were confirmed by the results of full atomic modeling, and the principal regularities responsible for the structure, stability, and properties of the supercharged polyplexes have been elucidated for the first...


Medulloblastoma is a common tumor in children, but is rare in adults. It is the second most common cause of cancer-related death in patients under 15 years. The presence of a median or paramedian enhancing cerebellar mass, often compressing the fourth ventricle may indicate the presence of this tumor. Genetic and molecular markers offer a new approach to the understanding and classification of medulloblastomas. Hence  we have come to understand medulloblastoma not as a sole disease but rather, as a group of clinically and molecularly distinct pathologies. Magnetic resonance imaging of the spine and lumbar puncture must be performed in all patients as part of the assessment of the extent of disease, since spinal leptomeninges are common sites for metastatic dissemination. Ideally, its treatmeant involves an interdisciplinary group that provides surgery, radiotherapy, and chemotherapy. Prognosis depends upon variables such as age (under three years), metastatic dissemination, residual tumor after surgery, large cell/anaplastic histological variant, and group 3 tumor (MYC amplification group).


As has been well documented, from the days of its early expansion in the 1950s television was widely situated as a 'feminised' medium, consumed in the domestic space and subjected to a process of gendering that has been articulated and facilitated in numerous ways, from advertising to scheduling to theories of spectatorship. This 'feminising' of television occurred despite the predominance of men in its management and the 'masculine bias' of many of its overarching ideologies.1 Heavily marketed to women consumers in the post-war period in both the United States and United Kingdom as it entered an era of substantive growth, Janet Thumim notes that in this 'formative period', women 'were acknowledged to be central to the project of inserting television into domestic spaces and routines'.2 Subsequently it has been widely constructed for a good part of its history as being consumed most predominantly by (undiscerning) women audiences, with the image of the housewife viewer tuning in for her daily dose of daytime television proving enduringly prevalent. More recently, however – particularly in the contexts of changing and increasingly 'high-spec' technologies; the burgeoning movement of television into spaces outside the home; and the latest 'golden age' of quality television drama – this notion of a 'feminised medium' has increasingly held less currency. As Rob Schapp notes, 'The television system of today constitutes too sophisticated, complex and expensive an array to escape statusenhancing masculine associations.'3 Nevertheless, the 'special relationship' long thought to exist between women and television remains at the very least an integral part of the medium's history. Significantly, this is apparent also in the way that the medium has long been perceived to provide a greater breadth of opportunity for its women actors and 'personalities', particularly as they aged, than has cinema for its women stars. Patricia Mellencamp, for example, has argued,


The Shokuiku Basic Act1) was enacted in June 2005 for the purpose of cultivating a healthy mind and body among citizens over the course of their entire lives and nurturing a rich sense of humanity in response to lifestyle and social changes accompanying Japan's rapid economic growth and an increasingly diversified sense of values regarding individual eating habits and food. The preamble of the Shokuiku Basic Act emphasizes shokuiku targeted at children in particular; "Food, more than anything else, is important to ensure that children develop a rich sense of humanity and the strength to live." Moreover, Article 5 of this Act mentions the roles played by parents and school personnel in children's shokuiku, indicating that aggressive steps should be taken to promote shokuiku: "Persons engaged in the education and upbringing of children must have an adequate awareness of the importance of shokuiku and take the necessary steps to promote shokuiku among children." Article 20 discusses the proliferation of knowledge regarding the establishment of a guidance system, the implementation of a school lunch program that takes advantage of characteristics unique to the school or local community and the promotion of shokuiku among children through various learning experiences conducted as part of the educational curriculum. It also discusses the effects of under-eating or obesity on health and measures to be deployed to encourage healthy eating habits among children along with healthy mental and physical growth through the effective promotion of appealing food and nutrition education at schools, day care centers and other educational institutions. This indicates the considerable Trends in Intervention Studies on Food and Nutrition Education in Japan Utilizing the School Lunch ̶ A Systematic Review Yoko Hosoyamada* and Kimiko Miyahara* *1Department of Nutrition and Dietetics, College of Nutrition, Kanto Gakuin University *2Department of Nutrition, Faculty of Health Care, Kiryu University doi:10.5264/eiyogakuzashi.76.S50


ABSTRACT In an important sense, the history of the United States is a bloody record of war. Founded less than two and a half centuries ago, the US has fought more than two hundred wars. War has brought the US enormous political, economic, territorial and ideological benefits, which is the reason why the country has waged wars so frequently. Today the US, at the center of a new type of empire of financial colonialism, continues to ignite wars in many parts of the world in order to maintain the dividends from its hegemony. It has thus come to pose a danger to the world. The interest group that lies behind these wars has become the world's largest and most evil terrorist organization. Killing in the name of liberty is the consistent, criminal logic of the US, which commits frequent outrages against humanity and human rights. The rivalry between the US and other countries and peoples has never been a clash of civilizations, but instead, a battle between barbarism and civilization. When we confront the United States, that has devoted itself to building a system of Prompt Global Strike (PGS), we must, as Mao once said, cast away illusions and prepare for struggle.


The article attempts to trace the connection of the famous Russian scientist Mikhail Lomonosov with Kiev-Mohyla Academy, which was famous not only in Ukraine but in Russia thanks to its teachers (Latin teachers, philosophers, rhetoricians, historians, grammarians) and had at that time some features of European-style university and was older than Moscow Spassky schools.


was to test an administrative model. Beginning with the first experiment, it became readily apparent that the manner by which cash allotments were administered; i.e., the rules, regulations. and policies denoting program restrictions and defining the amount of administration, was intricately linked with the measurement of labor-supply effects. By varying technical program requirements, labor-supply effects could be observed under different types of administrative conditions. This in turn would create a broader picture by which to assess the responsiveness of an administrative system and also permit selection of those key elements and technical features that could be incorporated into current income maintenance programs such as AFDC/AFDC-UP.


In this paper, we prove weak (p,q) inequalities for fractional integral operators on generalized non-homogeneous Morrey spaces for 1 � p < q < 1 . The proof involves an inequality for the modified HardyLittlewood maximal operator and the Chebyshev inequality. Our results generalize those obtained by Garcia-Cuerva and Gatto [1] and also extend those by Sihwaningrum et al. [5].


Most human T cells express the TCR a/Il and either CD4 or CD8 molecules (single positive, SP); how-ever, small numbers lack CD4 and CD8. In inbred mice, a/,B CD4-CD8- (double negative, DN) T cells preferentially ex- press certain 13 variable region (Vp) families and may arise via unique developmental pathways. Increased percentages of a/,B DN T cells have been identified in some human and murine autoimmune and immunodeficiency dis . How-ever, their contribution to disease pathology or normal immunity is unknown. To study the cell surface phenotpe and TCR diversity of human a/,B DN T ceUls, these cells were isolated from the peripheral blood of healthy adults. The proportion of a/f DN T cells expressing molecules associated with activation (HLA-DR), previous exposure to antigen (CD45RO), and cytotoxic function (CD56, CD57, and CDllb) was increased relative to SP T cells. The TCR Vp3 repertoire of a//9 DN T cells was different from that of a/fl SP T cells, although most major gene families were present. For example, higher proportions of Vpll, a minor gene family in peripheral blood leukocytes, were found in most a/f DN T-cell samples. In contrast to


There is a relationship between the way of living and the use of public transport. To verify this hypothesis a study has been carried out based on the theory of Pierre Bourdieu. Following this theory there are two stratifications in the society, which have their roots in money and education as the sources of prestige. These are the motives for an economic and a cultural way of living. This paper shows a clear correlation between public transport and a cultural way of living, even when other variables such as age and having a driving licence are also considered. For the covering abstract of the conference see IRRD 884093.


In this study, the residual stress of boron-doped diamond (BDD) films is investigated as a function of boron doping level using X-ray diffraction (XRD) analysis. Boron doping level is controlled from 1000ppm to 9000ppm by dissolving trimethyl borate into acetone. BDD films are deposited on silicon wafers using a bias-enhanced hot filament chemical vapor deposition (BE-HFCVD) system. Residual stress calculated by sin2 ψ method varies linearly from −2.4GPa to −1.1GPa with increasing boron doping level. On the BDD film of −1.75GPa, free standing BDD cantilevers are fabricated by photolithography and ICP-RIE processes, then tested by laser Doppler vibrometer (LDV). A cantilever with resonant frequency of 183KHz and Q factor of 261 in the air is fabricated.


Details are given of a method for determining the viscosity of cement paste. Based on analyses of the viscosity of cement pastes varying in water/cement ratio, a viscosity curve can be plotted for each type of cement. It was shown that, in exposed concrete structures, the viscosity of the cement paste must not fall below a limit viscosity if the formation of filaments on the surface of the exposed concrete is to be avoided. This limit viscosity corresponds to a certain water/cement ratio which is defined as the limit water/cement ratio for exposed concrete. This limit ratio is not constant for all types of cement, but is an index which is a function of the cement and which must be determined for each cement before laying begins. Other possible applications of cement paste viscosity measurements are outlined. /IRRD/


The fused use of the long-focus camera and telemetry LiDAR is necessary for advanced long-distance detection requirements in autonomous driving vehicles and unmanned subways, and the extrinsic parameter calibration is a precondition for multi-sensor fusion use. However, the inaccuracy of long-focus camera detection and low accuracy of data association between LiDAR-camera make the calibration a challenging problem. In this paper, we propose a novel calibration method that treat the detection poses as variables in the optimization framework, which significantly reduces the impact of detection errors on calibration accuracy. Furthermore, we construct 3 error terms to obtain better estimation of the variables, and the designed error terms only require plane-to-plane data association, avoiding incorrect data association that leads to failure in extrinsic parameter estimation. Then we made a full comparison with other methods through real-world experiments, which showed that our method achieves the best calibration result.


In this study, total phosphorus (TP) inactivation by using Alum at lake inlet was carried out. Jar test was used to optimize alum dose and effect of pH was studied. The tests resulted in immediate improvements in water quality. Tests showed that alum of 15-20 mg/L was sufficient to decrease TP from around 0.1 mg/L to below 0.025 mg/L, which is limiting value for eutrophication. Test study is also conducted to see the effect of pH on alum, it is seen that at a pH of 6, alum dose application can be reduced to between 5-10 mg/L.


Currently,old age,outdated knowledge structure,low educational level,low professional ranking and other problems still exist among general practitioners in the community and in a way restrain the development of community health service.There are mainly two categories of general practice(GP) trainees,serving general practitioners and post-graduate medical students.Based on the background and requirements of the trainees,training programs should be carried out with the six core competencies of Accreditation Council for Graduate Medical Education(ACGME) as the goal,the learning pyramid and competency pyramid as the theoretical support.Medical theories,clinical skills and clinical competence assessment should be integrated to form the training-assessment system.Various training approaches and all-round competency assessment should be applied to improve training results.


In this article, we are defining a proposed architecture that can resolve the main problem of high frequency trading which is the maturity level of financial data used by robot trader. The volume of markets data which comes every fragment of second, has caused a fatal problem in decision making on market. Any engendered market anomaly of robot trader can be propagated on the multiple markets due to the interaction between them and can be the cause of several problems in financial markets. The concept of our solution is based on endowing artificial intelligence of robot trader with auto regulation capacity following financial knowledge base.