Objective To study the using low dose beauty right around the time of anesthesia pyrimidine effects on blood pressure high blood pressure in elderly patients. Methods 112 hypertension routine anesthesia surgery elderly patients randomly divided into observation group and control group, each group 56 cases; Observation group with small doses of 4 μg/ml right beauty, pyrimidine vein pump into the control group vein pump into the right amount of 0.9% sodium chloride solution, compared two groups of perioperative blood pressure changes. Results Two groups of systolic blood pressure difference was statistically significant(F = 8.731, P = 0.036), the observation group 5 min after the treatment, 30 min charge is lower than the control group(P 0.05), there are differences between the two groups of heart rate difference(F = 7.835, P = 0.042), the observation group 5 min after the treatment the heart rate is lower than the control group(P 0.05), two groups of blood oxygen saturation, the difference was statistically significant(F = 9.635, P = 0.021), 5 min after the treatment group is lower than the control group(P 0.05); Two groups of open time, extubation time no statistically significant difference(t = 0.693, P = 0.489; t = 0.621, P = 0.536). Conclusion Low dose of the right around the time of anesthesia tora pyrimidine on hypertension in elderly patients with apparent calm, and can ensure that around the time of anesthesia in patients with loop stability.


Adolescents in communicating about their sexual and reproductive health (SRH) issues are faced with the obstacles created by expected social norms and taboos related to sexuality and gender. This study aims to determine the relationship between adolescent-parent communication and its relationship with safe sex behaviour among adolescents. The study was a descriptive cross-sectional. Data was collected from 400 adolescents in Ife-East local government using a pre-tested semi-structured questionnaire. We used a multistage sampling technique to select the required study subjects. We carried out simple frequencies and chi-square. Fifty –five percent (55.3%) of the respondents were females, while 44.8% are males. The mean age (±SD) of the participants was 15.50 ±1.55years. Of the respondents, only 37% had good knowledge of sexual and reproductive health issues, while 63% had poor knowledge of sexual and reproductive health issues. The predictors of adolescent parent communication among respondents are private schools (OR=2.546, P = 0.005, CI=1.327-4.885), Female sex (OR=12.128, P<0.001, CI=11.590 – 25.534), family size (OR=14.772, P= 0.003, CI=13.037 –20.015) and good knowledge of sexual and reproductive health issues (OR=19.521, P= 0.007, CI=19.521 –29.078). There is a statistically significant relationship between adolescent parent communication and safe sexual behaviour (X2=152.998, P <0.001, df = 1). The findings of our study revealed that adolescents were not communicating much with parents about sexual and reproductive health issues; and that there is an association between adolescent parent communication and safe sexual behaviour.


The research attempt to increase flexibility in shop floor and improve rate of production through maintenance engineering policies. The research is grounded on analysis of data collected from manufacturing based MSMEs and review of literature and data of spare parts published in referred journals. The study derives a further framework model comprising three strategies (Supply chain management, inventory management, and maintenance engineering) to improve rate of production. The aforesaid process is used to identify problems that occur during machine breakdown. The paper provides a research substitute machine to manage problems during breakdown of machines so that production is not hindered.


South Kalimantan is an area that is very rich in natural resources that managed by many companies and it is inhabited by a majority of Muslims which are as the potential of zakat, infaq and alms so large amount, but the results of the funding collection of zakat, infaq and alms at National Zakat Agency of Province South Kalimantan are still not maximal. This research is a qualitative descriptive research and focused on the discussion of the strategy of zakat, infaq and alms fundraising at National Zakat Agency of Province South Kalimantan, with data collection techniques by means of observation, interviews and documentation. The results of this study indicate that the implementation of the strategy of zakat, infaq and alms fundraising at National Zakat Agency of Province South Kalimantan is still less effective and efficient, which is due to the concept of inappropriate strategy formulation and lack of evaluation of the implementation of the strategy. Then in implementing the fundraising strategy, there are several advantages, including the National Zakat Agency National Zakat Agency is the mandate of the Law, the potential for zakat in the province of South Kalimantan is very large. On the contrary, there are deficiencies that are owned by National Zakat Agency of Province South Kalimantan, which are: The number of human resources management of National Zakat Agency in Province South Kalimantan which is still lacking, the lack of operational strategies for Zakat, Infaq and alms fundraising and the mindset of "Ulama Sentris" in the community.


This research aimed to determine the influence of adversity quotient (AQ) on student mathematics learning achievement (MLA) of class VIII SMP Negeri 1 Narmada academic year 2019/2020. Population in this study consisted of 379 students and sample of the research is consisted of 80 students which are selected by using the purposive sampling technique. Data collection techniques in this research using questionnaires and test. The instrument of this research using a closed AQ questionnaire consisting of 50 statements and essay of pattern and sequence mathematics number consisting of 4 questions. The data obtained was analyzed using correlation and simple linear regression. Correlation coefficient (r) equal to 0,799, which indicate that relation between AQ on student MLA including was strong category. The contribution of AQ on student MLA, coefficient of determination is 60,684 %. This indicated AQ also affect the student's MLA of class VIII SMP Negeri 1 Narmada academic year 2019/2020 shown by liniear regression equation in this research is Y=-20,592+0,577X


The growing significance of migration on a global scale is generating increased scholarly interest in the subject, offering a fuller and more nuanced understanding of the nature and implications of different types of migration. However, research to date has presented divergent findings on the factors influencing the presence or absence of migration-induced conflicts, as most contributions are single-case studies focusing on different regions, levels of analysis, and measurements, whether applied to 'objective' or 'subjective' situations. We develop a framework to assess a wide spectrum of interactions between 'local' residents and 'migrant populations' by integrating the literature on ethnic conflict and considering the findings of studies that have investigated developed countries separately from developing countries; utilized a methodology specific to a particular discipline; or have focused on a single historical time frame or level of analysis. We propose a distinctive way of organizing and integrating the literature, incorporating three levels of analysis (independent variables) and a wide range of responses (dependent variables). We demonstrate that this framework enables researchers who employ one level of analysis at the expense of the others, or consider only one aspect or level of conflict, to assess the limitations and representativeness of their case studies; to identify gaps in operationalization and measurements of concepts and definitions; and to become aware of the trade-offs involved in their selection and scope of analysis.


Objective To screen the human glioma-associated genes by the large-scale oligo mi- croarray.Methods The total RNAs were isolated from 5 specimens of glioma and the normal brain tis- sues,and were reversely transcribed to cDNAs and labeled with the fluorescent Cy5-dNTP and Cy3-dNTP to prepare the hybridization probes.The mixed probes were hybridized to the large-scale oligo microarray of 22 000 genes.After washing and scanning,the fluorescent image was obtained and analyzed by computer. Results By applying the large-scale oligo microarray,242 differentially expressed genes in glioma were screened out among the 22 000 target genes,comprising 123 up regulated genes and 119 down-regulated genes respectively,including cell cycle related genes,cell apoptosis related genes and cell skeleton and ci- nete-protein related genes.Conclusion The analysis of gene expression profile of glioma based on the large-scale oligo microarray can realize high-throughput screening of the genes associated with the glioma, and it can help to rapidly explore the genes function.Further analysis of the obtained genes will help to un- derstand the molecular mechanism of the glioma.


Distributed Integrated Modular Avionics (DIMA) is an architectural approach consisting of distributed integrated processing resources connected by a mixed-critical communication network. Time-Triggered Ethernet (TTE) could be applied as the communication network to guarantee the real-time performance of traffic in DIMA. Data Distribution Service (DDS) is proposed to cope with the rapid variation of massive data exchange and information interaction. DDS architecture could only guarantee the real-time performance of distributed systems to some extent. However, the centralized data access middleware of DDS contributes to combining publish/subscribe architecture and time-triggered network in avionics system. In this paper, we first propose the publish/subscribe architecture for time-triggered network and introduce the window activation method based on the publish/subscribe architecture. Then we propose the path planning method for RC traffic to realize load balancing, which uses queuing theory to reduce the computational complexity and end-to-end delay of RC traffic. Experimental results show that compared to the original time-triggered network, the average end-to-end delay and worst-case end-to-end delay of RC traffic could be reduced by up to 12.01% and 21.82% respectively using the window activation method. Also, the online path planning method considerably reduces the average delay and the worst-case end-to-end delay by 75.86% and 22.86% respectively at most.


Three cases of secondary syphilis are described in whom a skin biopsy was performed. In all, the histology bore a striking resemblance to that of malignant lymphoid neoplasm.


[Objective]To understand the status in the prevention and control of water related endemic fluorosis in Huantai county.[Methods]Questionnaire was conducted on the construction of wells in the whole county based on "Standard of investigation on the prevention and control of endemic fluorosis in Shandong province".[Results]291 water-improving and defluoridation projects were completed in the county in 1991.Water improving project was completed in 100% of the villages where had endemic fluorosis.112 water projects were closed,not to be used,accounting for 38.49%.Of them,179 were used under normal condition,accounting for 61.51%.The content of fluoride in water in 134 projects was up to the standard,accounting for 74.86%.The content of fluoride in the water in Jingjia and Qifeng towns was higher and not up to the standard.172 new projects had been completed since 1992.Of them,146 projects were used under normal condition,accounting for 84.88%.112 water samples were collected, the content of fluoride in 91 samples was up to the standard,accounting for 81.25%.27 water samples collected in non-fluorosis areas were tested,of them 24 were up to the standard,accounting for 88.89%.[Conclusion]There were 25 thousand villagers living in the area where the content of fluoride was higher in water.The prevelance of endemic fluorosis was severe,prevention and control of endemic fluorosis should be strengthened,great effort must be taken to look for water source in which the content of fluoride was lower.


Abstract We obtained the complete mitochondrial genome of strain 754 of Philosamia cynthia ricini using the next-generation sequencing method. The sequence consists of 15,388 bp and encodes 13 protein-coding genes. The nucleotide composition of Philosamia cynthia ricini 754 was significantly biased (A, G, C, and T was 39.65%, 7.76%, 12.35%, and 40.24%, respectively) with A + T contents of 79.89%. Maximum likelihood phylogenetic analysis showed that the Philosamia cynthia ricini 754 is close to the Antheraea pernyi and the Antheraea yamaai.


Introduction: Amputees one of the most common disabilities that leads to the imbalance.The purpose of this study was to evaluate the effect of balance exersice with massage on static balance in amputated veterans unilateral lower limb.
Method: The statistical community in this study were amputated veterans unilateral lower limb above the knee. 30 patients with mean age of 5/3 ± 49, height 1/4 ± 171 and the weight of 1/3 ± 69 purposefully selected and randomly assigned to experimental and control groups. static balance measured by Tandem test with close eye in two groups. The experimental group performed for 20 sessions of balance exercises with massage. Massage before exercise and for 20 minutes was applied on lower limb.The control group only did their daily activities. Data were analyzed by SPSS 16 software.
Results: The results showed that balance exersice with massage improved static balance. The results showed that there is a significant difference between the two groups.
Conclusion: According to the results, balance exercises with massage improves static balance in amputated veterans unilateral lower limb. Therefore, it is recommended that for improve balance in amputated veterans unilateral lower limb use balance exercises and massage


Local land use regulation may restrict housing supply, with more stringent regulation associated with higher local housing prices, as demonstrated by the empirical literature. If so, demand spillover to surrounding communities, may moderate local house price increases. We develop and test a model for how spillovers affect local price outcomes. Using data for California, we show that relative income and relative restrictiveness matter for the impact of local regulation on local housing prices.


China's access to WTO has deep impacts on both China's economy and the sustainable development of Yangtze River Basin. Its negative aspects are :①The industries of steel, automobile, chemical and agriculture will be greatly challenged by intense international competition; ②The ecological environment will suffer great pressure with the opening, development, investment and construction in new stage. Its positive aspects are : ①China's access to WTO speeds up the transformation of government function and leads to, which sets a new phase for the protection of the Yangtze River ; ②It strengthens the "Green Barrier ", which will benefit the ecological environment as an exterior power; ③It moves China forward into a new era of great opening, which will make the Yangtze River focus of the world on both development and protection ; ④China's access to WTO and the success of Olympic games application make it possible to realize the strategy of maneuvering water earlier than planned. China and the whole world will step into an era of "water-valued" allocation of resources and layout of economy, which will make the opening, development and protection of the Yangtze River Basin more important than before.


Cannibalism – i.e., intraspecific predation – is a common phenomenon that often occurs when food is limited. Many phytoseiid species, including Phytoseiulus persimilis, are known to engage in cannibalism when food is scarce and when there is no possibility to disperse. Under natural conditions, however, especially the females of these predatory mites are known to disperse when food is scarce. Males, in contrast, are expected to stay and wait for potential mates to mature. While staying, they could then obtain food by cannibalizing. Because conditions under which these mites are usually cultured prevent dispersal, it has been suggested that prolonged culturing may affect cannibalistic behavior. We hypothesize that it should especially affect cannibalism by adult females, because they consume by far most food. We tested this by comparing two strains, one of which had been in culture for over 20 years, whereas the other was recently collected in the field. Because it is known that this predator can discriminate between kin and non-kin and prefers cannibalizing the latter, we also started isofemale lines of these two original strains, with the idea to construct lines with high kin-relatedness. We subsequently tested to what extent the adult females and males of the original strains and the isofemale lines fed on conspecifics from the same culture. In a closed system, we observed the behavior of adult predators that were offered conspecific larvae as prey. Males engaged more often in cannibalism than females, and females of the strain with the long culture history engaged more in cannibalism than those of the recently collected strain, both in agreement with our ideas. The original strains and the isofemale lines did not differ in cannibalistic behavior, suggesting that there was no large difference in kin-relatedness within the original strains and the isofemale lines. 51 AlexandraRevynthi-ch4_Vera-ch1.qxd 20/10/2017 14:50 Page 51


Recent instrumental advances have enabled scanning electron microscopy using a field emission gun (FEG) to be combined with an ultra high vacuum specimen chamber. The resulting instrument, the UHV‐FEG‐SEM, allows high spatial resolution microstructural and micro‐analytic information to be obtained reliably from clean surfaces for the first time.


Aim: We aimed to investigate the 6-month efficacy and safety of postprocedural 12-hour tirofiban administration versus 24-hour tirofiban administration in patients with ST-segment elevated myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). Methods: This retrospective study enrolled 349 patients with STEMI who underwent primary PCI. Following the administration of bolus tirofiban after primary PCI, those receiving a 12-hour tirofiban infusion as the maintenance dose were classified as group 1 (n = 123) while those receiving a 24-hour infusion were classified as group 2 (n = 226). In-hospital and 6-month major adverse cardiac events were recorded. Results: There were no statistically significant differences between the 2 groups regarding in-hospital efficacy (in-hospital death: 4.4% vs 5.7%, P = .600 and stent thrombosis 1.8% vs 1.6%, P = .921) and in-hospital safety (2.6% vs 1.6% for major bleeding and 5.3% vs 4.1% for minor bleeding, P = .562). During the 6-month follow-up period, the incidence of the recurrent revascularization (16.1% vs 15.5%, odds ratio [OR] = 1.05 [0.47-3.67]), the repeated nonfatal acute coronary syndrome and/or stent thrombosis (27% vs 24.4%, P = .598, OR = 1.02 [0.42-2.48]), and the cardiovascular deaths (6.6% vs 6.5%, P = .943, OR = 1.03 [0.43-2.43]) were comparable between group 1 and group 2. Conclusion: Our study revealed that 12-hour tirofiban administration versus 24-hour tirofiban administration in STEMI who underwent primary PCI was similar with respect to in-hospital efficacy and safety and major adverse cardiac events during 6-month follow-up.


Frontal radar imaging of human activities may be useful in certain applications, such as through-wall surveillance, where cameras and x-ray sensors cannot be deployed. High-resolution radar images are currently obtained using electrically large antenna apertures operating at high frequencies. However, high frequencies are heavily attenuated by most walls. Also, the implementation of a radar with lots of array elements and associated data acquisition channels is costly and complex. In this paper, we propose methods to generate high-resolution Doppler-enhanced radar images of moving humans at low carrier frequencies with limited number of antenna elements. When a human moves, different body parts give rise to distinct Doppler returns. The key feature of our method is to dynamically resolve multiple body parts of the human across three dimensions: Doppler, azimuth, and elevation. The additional Doppler dimension allows us to relax the resolution requirements in terms of the carrier frequency and number of array elements across the other dimensions. We further reduce the number of array elements below the Nyquist limits by incorporating compressed sensing principles into two-dimensional beamforming because compressed sensing is particularly suited for solving certain types of under-resolved problems.We test our technique on simulated electromagnetic radar scattered data from a moving human for different radar configurations.We also study the robustness of the proposed technique to noise.


Throughout our Nation's history, extraordinary women have broken barriers to achieve their dreams and blazed trails so their daughters would not face similar obstacles. Despite decades of progress, pay inequity still hinders women and their families across our country. National Pay Day symbolizes the day when an American woman's earnings finally match what an average American man earned in the year. Today, we renew our commitment to end wage discrimination and celebrate the strength and vibrancy women add to our economy. 1


Introduction The SARS-CoV-2 pandemic situation forced the Spanish Government to declare a home confinement that was prolonged for three months. The Health System had to focus almost entirely on the treatment of patients with Covid-19 infection and vulnerable populations such as people with severe mental illness were overlooked. In this context, mental health home care as an alternative to hospitalization became a first-line approachment for patients with an acute mental health disorder. Objectives The aim of this study is to describe the professional practice and the patients characteristics attended by a mental health team in Catalonia during the home confinement due to the SARS-CoV-2 pandemic. Methods This study includes the period between March 15, 2020 and June 21, 2020. Sociodemographic, clinical and team functioning variables were described. The patient data was obtained from medical history whereas the rest of information was collected through the creation of a database by the members of the assistencial team. Results Team's structure was changed with the creation of two mirror teams. Psychological attention was expanded and the weekend coverage was reorganized.During that period 40 patients were treated with a mean age of 47 years. There were no differences regarding the gender (50% were men and 50% were women). 87% of the patients lived with their family. 75% of referrals were made by the hospital and 90% were referred to community services upon discharge. Regarding diagnoses, 57.5% of the patients were diagnosed with a psychotic disorder (10% being reactive to Covid-19). A total of 482 visits were made, of which 51% were conducted in a telematic form. The mean time between the referral and the admission was 37.98h. The team accepted 97% of the referred patients with an occupancy rate of 112.4%. Conclusions The re-organisation of a home treatment team during the domiciliary lockdown allowed to increase the occupancy rate and offered a rapid response to patients, avoiding the need of conventional hospitalization and providing a proper care plan. Disclosure of Interest None Declared


Abstract Bentonite beds are described from a number of localities on Gotland, all in the oldest exposed Silurian beds (Upper Llandovery). Four beds are found, with characteristic intervals. They occur in beds which were supposed to belong to two zones, and it is suggested that the zones are partly facies (more or less calcareous) of the same age. A correlation with bentonites in Vastergotland is suggested.


Conveyor tray apparatus with air bearing and air curtain and methods of use are disclosed herein for use in manufacturing technical ceramics.


In this article a Bayesian filter approximation is proposed for simultaneous multiple target detection and tracking and then applied for object detection on video from moving camera. The inference uses the evidence lower bound optimisation for Gaussian mixtures. The proposed filter is capable of real time data processing and may be used as a basis for data fusion. The method we propose was tested on the video with dynamic background,where the velocity with respect to the background is used to discriminate the objects. The framework does not depend on the feature space, that means that different feature spaces can be unrestrictedly used while preserving the structure of the filter.


I THE PRESENT CONDITION OF THE ADMINISTRATION OF / THE PARLIAMENTARY GRANT, / Under the Committee of Council on Education, / WITH SUGGESTIONS, / FOR ITS SECURITY AND IMPROVEMENT. / [rule] / To the Lord President of the Council. / [25 lines of text.] Collation: 2 I3 cm. B-C8, p. [i] 2-32. $2.


The authors analyze recent immigration in the two Italian regions of the Veneto and Friuli-Venezia Giulia. The first chapter examines economic and demographic trends in Italy as a whole while Chapter 2 focuses on those trends in the two regions under examination. Chapter 3 is concerned with qualitative and quantitative aspects of immigration to the two regions from outside the European Community. Chapter 4 looks at how immigrants participate in both the regular and informal economies. Chapter 5 considers several issues including the social consequences of immigration and how the governments of Italy West Germany and France have attempted to control international migration through legislation.


The 2010 Society for Melanoma Research Congress in Sydney, Australia represented a crossroads for the melanoma field in several respects. For the first time, a molecularly targeted therapeutic approach has been clinically validated with two highly selective v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitors (Flaherty et al., 2010). Groundbreaking clinical trial results were presented for the phase II trial of PLX 4032 and mature follow-up of the phase I trial of GSK2118436 (Kefford et al., 2010). With oncogenic BRAF having been a major topic of discussion at each of the SMR congresses since the meeting's inception in 2003, a milestone has been achieved with the successful translation of numerous groups work regarding the significance of BRAF as a potential therapeutic target. In the intervening years, a distinct subset of melanomas was found to harbor activating KIT mutations, and preliminary clinical investigations presented within the past year have demonstrated that clinically available KIT inhibitors produce tumor regression in a subset of patients whose tumors harbor these mutations (Carvajal et al., 2009; Curtin et al., 2006). Perhaps the most striking theme of this year's Congress was the presentation of so much ongoing research regarding potential resistance mechanisms to BRAF inhibitors. In addition to work regarding the downstream consequences of BRAF inhibition and potential compensatory mechanisms that might serve as complementary therapeutic targets, one could see an intersection between oncogene-targeted therapy and altogether novel therapeutic targets and many of the investigations into melanoma's fundamental biologic principles. It is increasingly clear that we must now turn our attention back to the laboratory if we hope to achieve the next quantum leap in outcome for patients with advanced melanoma. Having been discovered as an oncogene in melanoma in 2002, the therapeutic promise of targeting BRAF was first demonstrated with mRNA depletion of mutated BRAF in vitro (Davies et al., 2002; Wellbrock et al., 2004). At the time and for several years to follow, selective pharmacologic inhibitors were not available to further explore the mechanistic underpinnings of BRAF inhibition. However, the role of BRAF in inducing proliferation and senescence was established by several groups (Goodall et al., 2004; Michaloglou et al., 2005). And the complementary function of additional genetic alterations needed to facilitate full transformation and invasiveness was elegantly worked out in transgenic models (Dankort et al., 2009; Dhomen et al., 2009; Patton et al., 2005). Despite the presence of a vast array of concomitant genetic alterations, it is now clear that treatment of patients with metastatic melanoma tumors harboring a BRAF mutation results in profound tumor regression and symptom improvement in the majority of patients (Flaherty et al., 2010). This realization of the 'Gleevec moment' in melanoma has clearly revitalized the field and validated the work of many translational researchers. But clinical limitations of this approach have also been established and highlight the need for additional research to understand the compensatory mechanisms by which melanoma can ultimately resist such an initially highly effective therapy. For many years, the publications generated by melanoma researchers who were interested in understanding oncogenic and aberrant signal conduction incorporated pharmacological reagents that were far from relevant in the clinical setting. Conversely, the standard treatments used to treat advanced melanoma in years past hardly perturbed melanoma biology in a way that was sufficient to make research into melanomas adaptive response and potential vulnerabilities tractable. In some instances, suitably selective pharmacologic inhibitors existed, such as allosteric MEK inhibitors, but did not produce clinical responses to match what was observed in preclinical testing (Solit et al., 2006). With the results of the GSK1120212 phase I trial being presented within the past year, that gap between preclinical and clinical observations has been narrowed (Infante et al., 2010). But largely, highly selective pharmacologic inhibitors against other key signal transduction molecules have been lacking in years past and have left the field uncertain regarding the significance of the preclinical observations made within these three reagents. The use of LY294002 as a PI3 kinase inhibitor and sorafenib as a RAF inhibitor serve as two illustrative examples (Aziz et al., 2009; Wilhelm et al., 2004). Only recently have both privately and publicly funded pharmacologic development evolved


World War II presented American men with an opportunity to serve their country and thereby demonstrate their patriotism. This avenue to proving one's national loyalty became a double-edged sword for Japanese American males and radically impacted how this group envisioned and reconceptualized their relationship to the nation during and after the crisis of citizenship and national identity forced by the war. (1) The brave and groundbreaking services of the Women's Auxiliary Army Corps (WAAC) notwithstanding, American women of Japanese ancestry endured their own gender-specific challenges to negotiating a new understanding of Japanese American female citizenship that did not involve military service to the nation. Two works--one by a Japanese American woman and one by a Japanese American man--illustrate this essay's argument: that although socially constructed ideologies of gender determined the specific trials and tests Japanese Americans faced during World War II, responses to the marginalization of Japanese American citizenship can be characterized as exemplars of what I term "divine citizenship." Textual performances of divine citizenship bear witness to wrongs committed by the state against its subject while also modeling a renovated relationship between the state and the (wronged) citizen--a relationship in which reconciliation and forgiveness might occur. Although disparate in style, tone, narrative structure, and time frame, Mine Okubo's Citizen 13660 (1946) and John Okada's No-No Boy (1957) challenge the default notion of citizenship as a universal category. (2) These books can also serve as test cases for inquiry into how gender affects citizenship formation and revision. The title of Okada's work implies a gender specificity to the act of citizenship, while the title of Okubo's work obscures gender under national identity, a universalizing move that renders less visible her focus on how gender impacts citizenship. Begun while Okubo was in camp, Citizen 13660 reflects needs paramount during internment: to endure and negotiate the crisis. Writing post-war, Okada may have had sufficient critical distance to engage with issues of reconstruction. In the internment camp experience Okubo represents, females enjoy a latitude in gender norms, though they are still constrained in their ability to realize fully their identity as citizens. (3) Okada's novel takes up the question of the Japanese American's post-war relationship to the state and locates the particular challenges for men in a masculine context of military service and patriotism. At the same time, the novel treats female Japanese Americans as tools for personal growth, reifying their status as passive and maternal, paying little attention to their struggles to reframe citizenship. Both books underscore the existential angst that followed the government's actions and the way these actions forced Japanese Americans to question their identity and their relationship to the state. In this sense, Okubo's experience in the camps and Okada's treatment of the period after their dissolution offer parallel portrayals of citizenship reformulation during and after crisis. As works of Asian American literature, these books speak to specific historical events that loom large in Japanese American consciousness. As American texts, they offer a glimpse at how relationships among the nation, particular ethnic groups, and individuals are shaped, challenged, and reconfigured. Finally, as texts in which gender issues are linked to the internment, these books demonstrate how ties between a nation and its citizens are structured by ideologies of gender. This last point responds to those critics--most notably Shirley Geok-lin Lira, Sau-ling Cynthia Wong, and Jeffrey J. Santa Ana--who have called upon scholars to consider how Asian American texts link race and gender. (4) Wong and Santa Ana, in particular, underscore the need for critics to produce "historicized critical analyses of Asian American gender and sexuality" (214) in order to theorize American national identity. …


Image Enhancement has been used extensively in different fields like medical diagnosis, security purpose and feature detection. Various techniques for image enhancement have been proposed and implemented. Studies on image enhancement mainly focuses upon contrast enhancement, image sharpening and edge enhancement. This paper presents various latest developments in the field of image enhancement using fuzzy logic and retinex theory. Comparative studies of different algorithms have been stated in this paper with their features. Experimental analysis has been discussed for the same.


The landscape of surgical training is changing. Challenges, including work hour mandates, legal restrictions, institutional policies, patient expectations, and advances in surgical care, have resulted in an increased pursuit of fellowship training and have raised concerns about trainee readiness to enter independent practice. Residents at any stage of training may find themselves in situations where they demonstrate the ability to work with increasingly more autonomy yet continue to be relegated to the assistant's role. Perhaps more concerning is a scenario where these same residents nearing the end of training are not comfortable in the resident surgeon's role. Entrustment refers to the degree of autonomy a supervising physician confides in the trainee and is conspicuously lacking in the scenarios above. As physicians, we accept that patient care is paramount, but we cannot deny a simultaneous obligation to train our future surgeons. Does patient care suffer at the expense of trainee entrustment and vice versa? Herein, we weigh the importance of ensuring trainee competence for future patient care against providing the best possible care for patients treated in the present.


Wetland is the important natural resource and plays a key role in life.The wetlands of Hebei Province are important components of Chinese wetlands and Hebei Province covers many different wetland types,such as coastal wetlands,river wetland,lake wetland,march wetland and reservoir wetland.In this paper the implication,the ecological function and value of wetlands,classification,distribution,the main ecological function and problems were mainly discussed to promote the sustainable development and utilization of Hebei wetlands.


We study a class of optimal allocation problems, including the well-known bomber problem, with the following common probabilistic structure. An aircraft equipped with an amount x of ammunition is intercepted by enemy airplanes arriving according to a homogeneous Poisson process over a fixed time duration t. Upon encountering an enemy, the aircraft has the choice of spending any amount 0 ≤ y ≤ x of its ammunition, resulting in the aircraft's survival with probability equal to some known increasing function of y. Two different goals have been considered in the literature concerning the optimal amount K(x, t) of ammunition spent: (i) maximizing the probability of surviving for time t, which is the so-called bomber problem; and (ii) maximizing the number of enemy airplanes shot down during time t, which we call the fighter problem. Several authors have attempted to settle the following conjectures about the monotonicity of K(x, t): (A) K(x, t) is decreasing in t; (B) K(x, t) is increasing in x; and (C) the amount x - K(x, t) held back is increasing in x. Conjectures (A) and (C) have been shown for the bomber problem with discrete ammunition, while (B) is still an open question. In this paper we consider both time and ammunition to be continuous, and, for the bomber problem, we prove (A) and (C), while, for the fighter problem, we prove (A) and (C) for one special case and (B) and (C) for another. These proofs involve showing that the optimal survival probability and optimal number shot down are totally positive of order 2 (TP2) in the bomber and fighter problems, respectively. The TP2 property is shown by constructing convergent sequences of approximating functions through an iterative operation which preserves TP2 and other properties.


The quantum Casimir condensate of a conformal massive scalar field in a compact Friedmann universe is considered in the static approximation. The Abel–Plana formula is used for renormalization of divergent series in the condensate calculation. A differential relation between the static Casimir energy density and static Casimir condensate is derived.


The construction of Liaoning Instrument Vocational Education Group is an important measure to boost the development of instrument industry in Liaoning,as well as the reform and innovation of vocational education.By the perfection of governance structure,the construction of cooperation projects serving the instrument industry development and the vocational education development,setting up incentive mechanism to promote the steady development of the group,the group school-running mode featured by the government domination,the industry guidance,the university-enterprise cooperation integration comes into existence.At the same time,in the process of group construction three jobs should be focused on:the solution of funds shortage,the establishment of enterprise incentive mechanism and the introduction of supportive policy for vocational colleges.


In the eternal dominating set problem, guards form a dominating set on a graph, and at each step, a vertex is attacked. To defend against the attack, each guard either remains in place or moves to a neighboring vertex in order to form a new dominating set that contains the attacked vertex. We wish to determine the minimum number of guards required to successfully defend against any possible sequence of attacks, the eternal domination number. This number is known for 3 × n grid graphs when n < 26. This paper determines exact values of eternal domination numbers for 3× n grid graphs when n ≥ 26.


Reproductive governance and anti‐abortion discourse increased dramatically after the Dobbs decision ended Roe. To reproductive justice advocates, this decision came after the pandemic lockdown that left staff working from home and they see it as a human rights crisis. In light of these radical changes, how are reproductive justice debates framed in the United States by women of color? Drawing on ethnographic research, I suggest that while the abortion landscape has provoked more polarization, reproductive justice activists, particularly women of color, have deepened their commitment to their human rights and intersectional approach that advocates for the most structurally vulnerable.


In the context of a research project with the aim of investigating the influence of human-machine interfaces on the error-proneness of situation assessment in technical systems by humans, extensive user experiments have been conducted. The paper reports influences of a pattern oriented display (the mass data display) as well as time oriented displays (trend graphs) on the classification of process states. All interfaces that have been investigated were based on P&I (piping and instrumentation) diagrams, a threshold oriented visualisation form, which is commonly used in simulation and control (S&C) of large technical systems. Comparing the different displays with each other a strategy of "adding and removing" was applied. Primarily, the features of investigated displays are introduced and discussed. Based on the features of displays the assumed performance of each display is shown. Finally, the assumed and measured performances are compared with each other. The results are discussed as well in a taxonomy context.


This work was a contribution to the attempts aiming to solve the problems of estimation in biotechnological processes. These problems are related to the difficulty of on-line measurements of biological variables and to the fact that bioreactors are nonlinear time-varying processes with parameters uncertainties. For overcoming measurement difficulties, we proposed an adaptive estimation algorithm. This estimator is a combination of an asymptotic observer and an adaptive estimator. The objective of this estimator is to jointly estimate the states and the unknown kinetic parameters of a denitrification process. The process considered is a continuous-flow denitrification system in which a bacterial culture of Pseudomonas Denitrificans occurs: the biomass starts with consuming the acetic acid and the nitrate, and rejects some nitrites. Then, it continues to consume the acetic acid but the rejection of nitrites decreases. The simulation results seem to prove the performance and the robustness of the proposed estimation algorithm in spite of parameter variations and noisy measurements.


The initial exploration and summarization on the bilingual teaching of human and animal physiology in a regional university were carried out.The teachers who teach physiology bilingually should not only expert at the professional knowledge,but also have the ability to listen,speak,read and write;the appropriate bilingual or foreign teaching materials should be selected for the student in the regional university.In the course of teaching,intact En-glish courseware may be used and the teaching languages may be changed based on the contents.In addition,some other teaching steps such as class hours,lesson plan,examination and paper scoring were discussed.


Research progress and some emerging research orientations of major fields in fs laser pulse interaction with water are briefed, and the application prospect of these research are described.


The present invention discloses a circuit and method for reducing power consumption in a microprocessor. The method comprises extracting a current instruction; determining whether the current instruction requires access to a register file; When the judgment result is required to access the register file, allowing the microprocessor to perform from the temporary current command data; and when the judgment result is not required to access the register file, allowing the microprocessor to perform the data register from the previous instruction.


Simple Summary Currently, breast contrast-enhanced MRI is the most sensitive imaging technique for breast cancer detection; however, its specificity is low given the common characteristics shared by benign breast lesions and some cancers. This leads to a high number of false-positive cases and, therefore, unnecessary biopsies. Multiparametric MRI including diffusion-weighted imaging assists in this task by increasing the specificity for breast lesion discrimination. Nevertheless, interpretation of breast MRI is still highly dependent on the reader's level of experience. Our work combines radiomic features extracted from multiparametric MRI to generate predictive models for breast cancer differentiation. Additionally, decision support models were compared with the performance of two breast dedicated radiologists for lesion differentiation. Our work proves the potential of multiparametric radiomics coupled with machine learning to be implemented in clinical practice for lesion differentiation on breast MRI. AI algorithms show value to assist less experienced readers, improving the accuracy for breast lesion discrimination. Abstract This multicenter retrospective study compared the performance of radiomics analysis coupled with machine learning (ML) with that of radiologists for the classification of breast tumors. A total of 93 consecutive women (mean age: 49 ± 12 years) with 104 histopathologically verified enhancing lesions (mean size: 22.8 ± 15.1 mm), classified as suspicious on multiparametric breast MRIs were included. Two experienced breast radiologists assessed all of the lesions, assigning a Breast Imaging Reporting and Database System (BI-RADS) suspicion category, providing a diffusion-weighted imaging (DWI) score based on lesion signal intensity, and determining the apparent diffusion coefficient (ADC). Ten predictive models for breast lesion discrimination were generated using radiomic features extracted from the multiparametric MRI. The area under the receiver operating curve (AUC) and the accuracy were compared using McNemar's test. Multiparametric radiomics with DWI score and BI-RADS (accuracy = 88.5%; AUC = 0.93) and multiparametric radiomics with ADC values and BI-RADS (accuracy= 88.5%; AUC = 0.96) models showed significant improvements in diagnostic accuracy compared to the multiparametric radiomics (DWI + DCE data) model (p = 0.01 and p = 0.02, respectively), but performed similarly compared to the multiparametric assessment by radiologists (accuracy = 85.6%; AUC = 0.03; p = 0.39). In conclusion, radiomics analysis coupled with the ML of multiparametric MRI could assist in breast lesion discrimination, especially for less experienced readers of breast MRIs.


This paper reports analytical modelling and analysis of the temperature dependence on the device characteristics of the AlGaN/GaN high electron mobility transistors (HEMTs). A physics-based model is proposed in this study in order to correctly predict the gate Schottky barrier height (ΦB), Fermi-level from conduction band energy (EC-EF), two-dimensional electron gas (2DEG) sheet density, gate threshold (Vth) and sub-threshold voltages (ID-VG), and drain current-voltage (ID-VD) characteristics under various high temperature (300K~500K) conditions. The analytical results are then verified by comparing with the laboratory measurement as well as the numerical results obtained from the Sentaurus TCAD simulation. The proposed model is found to be useful for power electronic device designers on the prediction of the AlGaN/GaN HEMT device performance under high temperature operation without the use of heavy numerical solving process that requires complicated customized computer coding.


The new PTI government has made a break from the past by announcing that the centerpiece of its economic strategy will be Human Development. It can be argued that focusing on the development of human capabilities can enable individuals to lead the kind of life they consider meaningful. In so doing, the potential of a nation for enterprise, innovation and creativity can be actualized to enrich not only the economy, but human civilization itself. The economic strategy required to achieve this aim involves a new growth process that is based on equity and the conservation of the environment for sustainable development.2 In this essay3 we will indicate four specific policy initiatives to begin the process of inclusive and sustainable development.


The speed and direction of air flow through complex terrain are difficult to define. Both impact sensible and latent heat flux exchanges at the surface. Evapotranspiration (ET) models such as Mapping EvapoTranspiration at high Resolution with Internalized Calibration (METRIC™) estimate ET as a residual of the surface energy process and are thus sensitive to aerodynamics, including terrain‐induced impacts on roughness governing convective heat transfer (H). There is a need to explore the sensitivities of H estimation and thereby ET estimation to wind speed and terrain roughness in mountainous areas and to determine the merit of operating complex mesoscale wind field models in conjunction with the energy balance process. A sensitivity analysis is explored in METRIC where we increased wind speed in proportion to a relative elevation parameter and we increased aerodynamic roughness to assimilate impacts of relative terrain roughness, estimated in proportion to standard deviation of elevation within a 3 km locality. These aerodynamic modifications increased convective heat transfer in complex terrain and reduced estimated ET. In other sensitivity runs, we reduced estimated wind speed on estimated leeward slopes. Estimated ET with and without these sensitivity adjustments is shown for mountainous areas of Montana and Nevada. Changes in ET ranged from little change (<5%) for lower slopes to about 30% reductions on windward slopes and 25% increases on leeward slopes for some mid to high elevations in the Montana application.


We analyse the constraints obtained from new atomic clock data on the possible time variation of the fine structure `constant' and the electron-proton mass ratio and show how they are strengthened when the seasonal variation of Sun's gravitational field at the Earth's surface is taken into account.


The primary objective of this project is to develop a robust, high-performance parser for English by automatically extracting a grammar from an annotated corpus of bracketed sentences, called the Treebank. The project is a collaboration between the IBM Continuous Speech Recognition Group and the University of Pennsylvania Department of Computer Sciences. Our initial focus is the domain of computer manuals with a vocabulary of 3000 words. We use a Treebank that was developed jointly by IBM and the University of Lancaster, England, during the past three years.


In the current study, the reduction of CaO-Al2O3 inclusions in steel by the subsequent addition of aluminum is revealed through industrial trials, laboratory experiments, and thermodynamic calculations. During the industrial production of the Al-killed Ca-treated steel, the Al2O3 content in CaO-Al2O3 inclusions increased from 72.05% to 79.83%, after the aluminum addition. In laboratory experiments, the addition of aluminum increased the Al2O3 content, and meanwhile lowered the contents of CaS and CaO in the inclusions. The average diameter of the inclusions decreased and the number density increased after the Al addition in steel, due to the formation of tiny inclusions. Based on the thermodynamic consideration, the transformation of the inclusions was attributed to the re-equilibrium of the reaction between steel and the inclusions after aluminizing. The Al2O3-riched calcium aluminate with a high melting point increased the possibility of the nozzle clogging during the continuous casting process, reducing the effect of the calcium treatment. Therefore, the addition of aluminum after calcium treatment should be avoided as far as possible.


: This paper examines China's topology and the close relationships between its government and different religions, encompassing Taoism, Buddhism, and Confucianism, manifested by music. Under the government's authority and guidance, these religions' music does not express political views or social transformations and instead seeks inner peacefulness and facilitates the fulfilment of religious or ritual purposes. The rise of Chinese Christian praise music in the recent two decades reflects a transformation that Christianity will likely continue to grow with more praise songs covered and created in China and enrich the diversity of Chinese religious music.


To the Editor, Your journal's recent article describes a second family with autosomal recessive colobomatous microphthalmia and developmental delay (Chassaing et al., 2016), supporting the association of TENM3 mutations with eye abnormalities, and further confirming the earlier report by Aldahmesh, Mohammed, Al-Hazzaa, and Alkuraya (2012). Coloboma refers to an ocular birth defect resulting from abnormal closure of the optic fissure during the fifth to seventh week of embryonic stage in humans (Nakamura, Diehl, & Mohney, 2011). Failure of the fissure to fuse can lead to coloboma of multiple regions of the eye such as iris, zonules and ciliary body, choroid, retina, and optic nerve. Coloboma is a genetically heterogeneous disorder that is often associated with additional ocular features such as microphthalmia, anophthalmia, micro cornea, retinal detachment, and ocular movement disorders. Multisystem abnormalities involving neurological, facial, and urogenital abnormalities have also been described to be associated with optic fissure closure defects, of which neurological abnormalities are relatively common (Skalicky et al., 2013). Odz3, the vertebrate orthologue of Teneurin transmembrane protein 3 encoded by human TENM3 gene, has been well studied for its role in axon guidance, homophilic cell adhesion, and ocular development (Ben-Zur, Feige, Motro, & Wides, 2000; Leamey et al., 2007). So far, four patients from three families manifested with microphthalmia been reported due to bi-allelic mutations in TENM3 (Aldahmesh et al., 2012; Chassaing et al., 2016; Singh, Srivastava, & Phadke, 2018). We now report a fourth family of Indian origin having novel truncating mutation in TENM3 in two similarly affected sisters who manifested with motor developmental delay, eye abnormalities, without microphthalmia. The subjects in the study were consented under clinical protocol 76-HG-0238, approved by the Institutional Review Board of National Human Genome Research Institute. Two siblings born to nonconsanguineous parents were referred for the evaluation of ptosis and developmental delay. Maternal uncle had very severe visual loss and small eyes from history (details are not available). The older child, who is presently 5.5 years old, was initially seen at 2 years and 10 months and presented with global developmental delay. She started to walk at the age of 34 months. On examination, her weight was 19 kg (50th–75th percentile), height was 111 cm (50th percentile) and head circumference was 51 cm (25th–50th percentile) at 5.5 years of age. She had oval shaped cornea with inferonasal iris coloboma bilaterally and ptosis of left eye with a corneal diameter of 11 mm vertically and 9 mm horizontally. Her pupils were keyhole shaped and fundus examination revealed inferomedial retinal coloboma involving the optic discs and fovea (Figure 1a,b). The younger sister who is 5 years old also had oval cornea and history of nystagmus since birth. She had mild motor delay, spoke only few words and was walking with support by 20 months of age. Currently she is 4 years 3 months old and has a weight of 14.5 kg (10–25th percentile), height of 104 cm (50–75th percentile) and head circumference of 47.5 cm (<3rd percentile). She had bilateral partial ptosis, left convergent squint, and oval shaped cornea with inferonasal iris coloboma in both the eyes. Detailed ophthalmological evaluation revealed a corneal diameter of 9 mm vertically and 7 mm horizontally. Like her sister, her pupils were keyhole shaped and fundus examination revealed inferomedial retinal coloboma involving the optic discs but sparing the fovea (Figure 1c,d). The phenotypes of the patients in this study overlap with the earlier reports, including similar ocular defects of iris and retinal coloboma, nystagmus, and esotropia. Neurological problems of delayed milestones, intellectual disability, and speech delay seen in the sibs in this paper are consistent with the earlier patient reported by Chassaing et al., 2016. However, patients in this report did not have microphthalmia and the retinal coloboma was complete in both patients, but spared the fovea in one patient and involving fovea in the other. In addition, we observed ptosis in both patients, while this feature was absent in previously reported patients. A comprehensive clinical comparison of the sibs with previously reported individuals are shown in Table 1. We employed whole exome sequencing to identify the genetic etiology. For exome analysis, we used autosomal recessive mode of inheritance as a filter because the female patients are two similarly affected siblings from a nonconsanguineous family. Further variant filtering strategy used included recessive variants with minor allele frequency < 0.01 in publicly available databases such as ExAC, gnomAD and 1000Genome, and pathogenic in silico predictions according to online prediction tools (SIFT, Polyphen, Mutation Taster, and CADD). Final analysis revealed homozygous variants in two candidate genes: TENM3, NM_001080477.3: c.1857T>A; p. Cys619* and MBTD1, Received: 3 August 2018 Revised: 17 September 2018 Accepted: 18 September 2018 DOI: 10.1002/ajmg.a.40658


The final chapter considers how the Merchant Adventurers came to lose its domestic privileges following the Glorious Revolution in a way that proved to be lasting. Although usually this has been seen as an inevitable consequence of the long-term decline in the volume of the cloth trade and the political position of the Company, the chapter argues that this was a more contingent process than is usually realized. In fact, the Company had been on the cusp of a political revival as recently as the 1680s. The chapter considers the reasons for this, in terms of the Company's long-term relationship with the English state, and its struggle to maintain its monopoly against interlopers. The reasons why the Company failed to capitalize on the upturn in its political fortunes are connected to the structural changes in the Company's trade, which saw its residences in Hamburg and England increasingly at odds over the purposes of the Company, and how it was to be governed. This contest was reflective of broader changes in the position and activities of merchants in a period of growing multilateral trade.


OF THE THESIS FACTORS AFFECTING GROWTH AND SURVIVAL OF SNOWY EGRET NESTLINGS by Lisa Borgia Florida International University, 1999 Miami, Florida Professor Victor Apanius, Major Professor It is widely believed that wading birds in the Everglades have declined as a result of historic water management practices. I determined growth rates for Snowy Egret (Egretta thula) chicks by assessed the nestling body condition through measurement of body weight and skeletal traits. A growth index was calculated as a residual of body weight regressed on age. A body condition index was calculated as the residual of body weight regressed on a skeletal trait (tarsus). Growth was significantly related to water level and hatch date. Survival rates were calculated to day 14, 21, and 50. Survival to 50 days of age was significantly related to hatch date and order. Survival to 21 days of age was significantly related to water level and hatching order. Survival to 14 days of age was marginally related to hatching order. Growth and survival is greatly influenced by water level and hatch date.


Recently, a novel group of CD34+ and S100+ spindle cell tumors with distinctive stromal and perivascular hyalinization showing recurrent gene fusions involving RAF1, BRAF, NTRK1/2/3, and RET has been identified. ALK rearrangements have been rarely reported in this group of tumors. We report a 24‐year‐old woman with a 1.5‐cm pink mass of the scalp. The tumor was made of spindle cells organized in fascicles or haphazardly arranged in a patternless architecture, with areas of stromal and perivascular hyalinization. The tumor cells diffusely expressed CD34 and S100, without SOX‐10 expression. The tumor showed diffuse immunopositivity for ALK. RNA sequencing using next‐generation sequencing (NGS) detected an EML4‐ALK fusion. This case extends the spectrum of this newly described group of CD34+/S100+ spindle cell tumors at the molecular‐genetic level. Dermatopathologists should be aware of this recent entity, as it may fall in the differential diagnosis of many other spindle cell tumors with CD34 expression. NGS‐based techniques should be performed when facing spindle cell tumors with similar morphology and immunophenotype. Identification of kinase fusions is essential for the precise classification and better knowledge of these tumors, and for targeted therapy in rare aggressive cases.


The explosive growth of electronic commerce will cause many changes in the way business is done worldwide. This talk will address the underlying causes and technologies that are enabling the evolution, and also a vision of a highly dynamic economy. Technical capabilities (bandwidth, computing power, storage capacity) are growing rapidly. Systems are moving toward standardized interfaces and distributed processing. Most important, software embodies ever more complex objects, including general business processes and models. Enterprise software will increasingly be built using business-oriented services that are negotiated and accessed over the network. Traditional business practices are characterized by rigidities of location, computing systems, software design, organization limit, closed long-term relationships, industrial sector, and national boundaries. In many cases, these will be replaced by new dynamics: pervasive e-business, distributed computing, network-based service components, virtual enterprises, competitive deal-making, cross-industry markets, and globalization


Although he only made two films, Jack Garfein, a central figure at the Actors Studio, is finally starting to enjoy the acclaim he deserves.


Andalusia is one of the important places that produced controversial thoughts on both philosophy and tasawwuf. Ebu Ishak Ibrahim bin Musa Al-Shatibi, an Islamic jurist had grown in this geography, in his book on principles of jurisprudence (usul al-fiqh) ?al- Muvafakat?, evaluates some sufistic thoughts from Islamic law?s point of view. This article, as an example of multi-disciplinary work, aims to reunite these thoughts with the readers. Normal 0 21 false false false TR X-NONE AR-SA /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Normal Tablo"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi; mso-fareast-language:EN-US;} Normal 0 21 false false false TR X-NONE AR-SA /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Normal Tablo"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi; mso-fareast-language:EN-US;}


Based on the research and exploration of the construction process of the steel reinforced concrete composite structure, this paper summarizes a set of systematic improvement methods for the design and construction of the section steel concrete composite structure. This method first improves the construction method of node connection. Splicing plates are staggered at the beam end to reduce the number of bolts. The BIM technology is employed to build a three-dimensional model to optimize the construction layout of the core area of the steel composite structure. In addition, the precise positioning of beams, columns, splicing plates, stiffeners, bolts, and welds can be obtained in advance. Therefore, the whole process of visualized construction can be realized to reduce construction cost and improve construction efficiency.


The construction and development of scenic spots is the foundation of regional tourism development,a successful tourist destination needs a group of tourist scenic spots with distinctive features. Western Hill tourism area is one of the fundamental tourism areas of tourism development in Kunming. This article advances the development strategies,tasks as well as safeguard measures by analyzing the environment,resource and market of Western Hill tourism area and so on.


A downlink sub-frame allocation method for a Worldwide Interoperability for Microwave Access (WiMAX) evolution system is provided. The method includes: the initial offset of an IEEE 802.16m frame is set as a deployment area coverage parameter, and all IEEE 802.16m base stations in the same deployment area coverage of a system set the initial position of IEEE 802.16m unit frames according to the initial offset of said IEEE 802.16m frame; said IEEE 802.16m base stations set initial sub-frames of the IEEE 802.16m frames as IEEE 802.16m downlink sub-frames; a super-frame control header carrying synchronizing symbols is sent in the initial position of the first unit frame of the super-frame, or the synchronizing symbols are sent in the initial position of the first unit frame of the super-frame, and the super-frame control header is sent in the initial sub-frame of the first unit frame of the super-frame; said synchronizing symbols and said super-frame control header are time division multiplexed in the first unit frame of the super-frame.


Moving, merging, and annihilating Dirac points are studied theoretically in the tight-binding model on honeycomb lattice with up-to third-nearest-neighbor hoppings. We obtain a rich phase diagram of the topological phase transitions in the parameter space of direction-dependent hoppings. We obtain the conditions for the three Dirac points to merge and for the tricritical points. We find that only very small third-nearest-neighbor hoppings are enough for the existence of the merging of three-Dirac-points and the tricritical points, if the system is sufficiently anisotropic. The density of states is obtained to be $D(\ensuremath{\epsilon})\ensuremath{\propto}{|\ensuremath{\epsilon}|}^{1/3}$ when three Dirac points merge, and $D(\ensuremath{\epsilon})\ensuremath{\propto}{|\ensuremath{\epsilon}|}^{1/4}$ at the tricritical points. It is possible to realize these topological phase transitions in the ultracold atoms on the optical lattice, strained monolayer graphene, or strained bilayer graphene.


Two species of the palmaean leaves are hitherto known ; one of them is Sabalites nipponicus (Sabal nipponica KRYSHTOFOVICH, 1918) emended by S. ENDO, 1934 ; the other is Sabalites taishuensis established by K. TAKAHASHI in 1958 as a new species. The former species occurred in the Eocene coal-fields of Takashima. Nagasaki Prefecture, Kyfishia, of Bibai in Hokkaidi5, and in the Oligocene coalfields in Northern KyfIshO, and Ube City. Yamaguchi Prefecture. The latter


In this paper, the interior inverse scattering problem of a cavity is considered. By use of a general boundary condition, we can reconstruct the shape of the cavity without a priori information of the boundary condition type. The method of fundamental solutions (MFS) with regularization is formulated for solving the scattered field and its normal derivative on the cavity boundary. Newton's method is employed to reconstruct the cavity boundary by satisfying the general boundary condition. This hybrid method copes with the ill-posedness of the inverse problem in the MFS step and deals with the nonlinearity in the Newton's step. Some computational examples are presented to demonstrate the effectiveness of our method.


Goal: Companies are increasingly concerned about the life cycle of their products in the economic and environmental perspectives. One of the processes that generates great financial returns is the injection molding process. But this process results in many impacts to the environment. The environmental concern has generated many studies involving this theme and the difficulty of measuring the impacts generated by this process. In view of the environmental concern and the injection molding process this study aims to review in the literature on eco-design tools based on the Streamlined Life Cycle Assessment of plastic injection molded products.Design / Methodology / Approach: The review of the literature was carried out by researching for complete articles published in three databases (Science Direct, Scopus and Web of Science), among the years 2013 - 2018, using combinations of keywords and Boolean operators.Results: Several studies revealed that injection molding generates many impacts, such as the high consumption of electricity caused by the emission of greenhouse gases and use of raw material.Limitations of the investigation: This paper is not free of limitations. The study analyzed the literature through three databases for a period of time and used a combination of keywords. It may be that some document has not been analyzed.Practical implications: The development of a rapid tool for the application of LCA studies will allow quick decision-making to the managers in the environmental perspective, besides reducing costs, reducing time with the application of complex studies, and assisting the designer to develop the Eco-design.Originality / Value: The study addressed the injection molding process and there are no studies in the literature that characterize this theme. Thus, a study that addresses this gap and evidences the importance of the development of an environmental tool that assists sustainable practices in the process of plastic injection molding becomes important.


Pancreatic pseudocysts are cyst colections without epithelial wall representing 75% of all pancreatic cyst collections.2 According to Atlanta classification,3 chronic pancreatic pseudocyst is that recognized after chronic pancreatitis without a previous acute attack.8 Three procedures have been described for the treatment of pancreatic pseudocyst: 1) external drainage, 2) internal drainage and 3) surgical remotion.9 However, because the technical endoscopic knowledge and percutaneous drainage, the surgical treatment has been modify.10 In the present case, the author reports an 8.6x10.1 cm. y 8.2x10 cm., chronic


The automatic generation process of digital house map includes scanning input of origianl map, image pressure-processing through medium filtering of two valued image, image fining with detection template of fine the contour curves in the map image into single pixel wide curves for topological conversion; image-to-image conversion through scanning from top to bottom and from left to right and image repair; detection with main map characteristic curves and decomposing house characterstic curve to separate house contour from other curves so as to obtain independent house contour main curves; andsectional process of house contour vectorization. The digital map has high position precision, and the said proces shas fast speed, short development period and low development cost.


There is much current interest in developing all-optical switching devices for applications in photonics. One direction of research, being pursued at the Laser Physics Centre at the Australian National University, is the development of organic conjugated polymer waveguides for this application. Poly(p-phenylenevinylene) (PPV) is a conjugated polymer with a high third order nonlinearity, making it a possible candidate for all-optical switching devices, but it also has high optical losses. These losses can be reduced when PPV is combined with a host matrix of poly(vinyl pyrrolidinone) (PVP) which has much better waveguiding properties. To make a practical all-optical switch, both high nonlinearity and low losses are necessary. The work presented here was motivated by the need to identify the cause of the optical losses in PPV-doped waveguides whether being due to absorption, an intrinsic characteristic of the material, or due to extrinsic causes such as scattering or waveguide irregularities. Since the polymer films are generally very thin (::::: 1 micron), standard spectrophotometer measurements are not able to resolve the absorption levels which are important even at the level of O. lcm-• This dissertation presents the preparation of a photodeflection spectroscopy system, able to measure the absorption in these films independently of other sources of waveguiding losses like scattering. This technique was used to measure the absorption spectra of thin films of PPV, PVP, and composites of PPV with PVP, determining that the absorption losses in the composite films were much smaller than the total losses which had been measured for waveguided light propagating in the films. Thus, the losses in the material are not limited by absorption, and so further attention to the extrinsic sources of loss may yield material suitable for the production of nonlinear optical devices.


To date, the exact distribution of the fundamental property of intrinsic angular momentum, or spin, in the proton amongst its constituents is largely unknown. Through observation of the production of the J/ψ particle in polarized pp collisions at RHIC we are able to further constrain the contribution of the gluon polarization to the total spin polarization of the proton by expanding the global data available into a new kinematic regime.


The soil invertebrate earthworm, play a key role in recycling of organic matters in soil. Aerobic, anaerobic bacteria and fungi are present in the gut of earthworm. The earthworm is backbone of agriculture. So play a vital role in the sole. The soil microbes are high in compared with earthworm gut. Microbes are high numbers of present in mid gut because undigested microbes are present in mid gut. The many nutrients are present in the given study soil sample. High bacteria and fungi present in soil compared with earthworm gut (Eisenia foetida). Study area high in numbers of earthworm soil nutrients are helped in increased culture of paddy yield.


We studied the effect of self-phase modulation and self-focusing on transient stimulated Raman scattering in high-pressure hydrogen by using high-energy, subpicosecond laser pulses. Adding argon to the hydrogen emphasizes the effect of self-phase modulation on stimulated Raman scattering by increasing the former effect without affecting the latter. The behavior of the observed stimulated Raman scattering falls into three regimes depending on input energy: normal stimulated Raman scattering at low energies, suppression by self-phase modulation at medium energies, and a recovery at high energies because strong self-focusing limits self-phase modulation.


Increased power dissipation in computing devices has led to a sharp rise in thermal hotspots, creating thermal runaway. To reduce the additional power requirement caused by increased temperature, current approaches apply cooling mechanisms to remove heat or apply management techniques to avoid thermal emergencies by slowing down heat generation. This paper proposes to tackle the heat management problem of computing platforms with a fundamentally new approach - instead of heat removal using cooling mechanisms and heat avoidance using dynamic thermal/power management techniques, this work investigates the mechanisms to recover wasted heat into reusable energy for sustainable computing.


Increased use of radiation in medicine, industry, and laboratories, requires safe conditions to be provided for its optimal use. One of the cases in which people are exposed to radiation, is during the detection of explosive materials by PGNAA method. Therefore, external dosimetry is necessary for workplaces where the method is used. In this study, Monte Carlo simulation program, MCNPX has been used to simulate gamma dose in the environment during the detection of explosive materials by PGNAA method. The simulated results were validated practically. The results indicate a good agreement between the simulated and measured data. The study demonstrated that MCNPX code can be used e ectively for simulating gamma dose in various environments.


Moreover, we also speculate this hyperactivity of inflammatory system also induces anticholinergic activity (AA) and this AA accelerates amyloid pathology [5]. Based on this speculation, we propose "the hypothesis of endogenous appearance of AA in AD" [6]. That is, when the downregulation of ACh reaches critical level, AA appears endogenously by way of hyperactivation of inflammatory system and accelerates amyloid pathology [5,6]. Because the factors those cause AA and now reported three other than downregulation of ACh, i.e., medication [7], physical illness [8] and mental stress [9]. Therefore, it is natural that when based on the small amount of deterioration of ACh other AA insert is added, AA also appears [10]. In fact, we showed the patient with AD at MCI level whose serum anticholinergic activity might be positive caused by both small amount of down regulation of ACh and mental stress [11]. Moreover, overburden of cholinergic system might also attribute to the appearance of AA because ACh is no more upregulated in order to compensate for AA insert (upregulation of ACh). Therefore there might be a possibility of the appearance of AA in other disease than AD. We also speculate there might be a possibility of the endogenous appearance of AA in depression and Lewy body disease (LBD). Increased activity of the hypothalamic-pituitary-adrenal (HPA) axis and the small amount of downregulation of ACh. It is plausible to conclude that in depression and LBD AA might appear endogenously [12,13]. In depression, the cholinergic system is burdened secondarily to the underlying depressive pathology. During remission, activity of cholinacetyl transferase (ChAT), an enzyme that produces ACh, might be sufficiently upregulated to compensate for the cholinergic burden caused by depressive pathology. However, at the pathological state (depressive state), more upregulation of ACh is not impossible because the ChAT activity is already upregulate. Therefore, in depression there might be a possibility of endogenous appearance of AA [14]. In delirium, we also speculate there might be a possibility of the appearance of AA in delirium. In delirium, increased activity of the HPA axis by exogenous factor, i.e., physical illness, medication or mental stress and the small amount of downregulation of ACh caused by aging or AD, AA also appears.


1 World Health Organization. WHO coronavirus disease (COVID-19) dashboard. 2020 [accessed 2021 Feb 18]. Available from: https:// covid19.who.int/. 2 Carf ı A, Bernabei R, Landi F; Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA 2020;324:603–605. 3 Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet 2021;397:220–232. 4 Logue JK, Franko NM, McCulloch DJ, McDonald D, Magedson A, Wolf CR, et al. Sequelae in adults at 6 Months after COVID-19 infection. JAMA Netw Open 2021;4:e210830. 5 Xiong Q, Xu M, Li J, Liu Y, Zhang J, Xu Y, et al. Clinical sequelae of COVID-19 survivors in Wuhan, China: a single-centre longitudinal study. Clin Microbiol Infect 2021;27:89–95. 6 Zhao YM, Shang YM, Song WB, Li QQ, Xie H, Xu QF, et al. Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery. EClinicalMedicine 2020;25:100463. 7 Huang Y, Tan C, Wu J, Chen M, Wang Z, Luo L, et al. Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase. Respir Res 2020;21:163. 8 Venturelli S, Benatti SV, Casati M, Binda F, Zuglian G, Imeri G, et al. Surviving COVID-19 in Bergamo province: a post-acute outpatient reevaluation. Epidemiol Infect 2021;149:e32. 9 Tenforde MW, Kim SS, Lindsell CJ, Billig Rose E, Shapiro NI, Files DC, et al.; IVY Network Investigators; CDC COVID-19 Response Team; IVY Network Investigators. Symptom duration and risk factors for delayed return to usual health among outpatients with COVID-19 in a multistate health care systems network—United States, March–June 2020. MMWR Morb Mortal Wkly Rep 2020;69:993–998. 10 Garrigues E, Janvier P, Kherabi Y, Le Bot A, Hamon A, Gouze H, et al. Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19. J Infect 2020;81:e4–e6. 11 National Institute for Health and Care Excellence. COVID-19 rapid guideline: managing the long-term effects of COVID-19. 2020 [accessed 2021 Feb 15]. Available from: https://www.nice.org.uk/guidance/ng188. 12 Maurizi CP. Postencephalitic Parkinson's disease, amyotrophic lateral sclerosis on Guam and influenza revisited: focusing on neurofibrillary tangles and the trail of tau. Med Hypotheses 2002;58:198–202. 13 Townsend L, Dowds J, O'Brien K, Sheill G, Dyer AH, O'Kelly B, et al. Persistent poor health after COVID-19 is not associated with respiratory complications or initial disease severity.Ann AmThorac Soc 2021;18:997–1003. 14 Centers for Disease Control and Prevention. Risk for COVID-19 infection, hospitalization, and death by race/ethnicity. 2021 [accessed 2021 Feb 18]. Available from: https://www.cdc.gov/coronavirus/2019-ncov/coviddata/investigations-discovery/hospitalization-death-by-race-ethnicity.html. 15 Sze S, Pan D, Nevill CR, Gray LJ, Martin CA, Nazareth J, et al. Ethnicity and clinical outcomes in COVID-19: a systematic review and metaanalysis. EClinicalMedicine 2020;29:100630. 16 Lam MH, Wing YK, Yu MW, Leung CM, Ma RC, Kong AP, et al. Mental morbidities and chronic fatigue in severe acute respiratory syndrome survivors: long-term follow-up. Arch Intern Med 2009;169:2142–2147.


The Objective Structured Clinical Examination (OSCE) is a highly valued performance-based competency assessment that is extensively employed in medical and health professions education. In pharmacy undergraduate programmes, OSCE is an integral component of the curriculum, constituting both formative and summative assessments of the course. When the COVID-19 pandemic posed an overarching challenge in the delivery of face-to-face teaching and learning activities, academic institutions around the world ineluctably transitioned to online mode of education. Conducting OSCEs on virtual platforms presents its unique set of challenges. In the absence of physical isolation and invigilation of students, the risk of cheating and collusion is particularly high during virtual OSCEs. With the experience of conducting high-stakes OSCEs on virtual platforms at two different campuses simultaneously, the authors outline several strategies that can be implemented to ensure the academic integrity of the assessment.


Utilization of whole blood total RNA samples on GeneChip expression arrays has shown reduced detection sensitivity compared with using fractionated blood samples (e.g., peripheral blood mononuclear cells, or PBMC1). This Technical Note describes the development of a Globin Reduction Protocol (GRP) that can be used to specifically reduce the α1-, α2-, and βglobin mRNA population in whole blood total RNA samples prior to target labeling to address this sensitivity issue.


How to define a system? This is a problem faced routinely in science and engineering, with solutions developed from our understanding of the processes inherent, to assessing the underlying structure based on observational evidence alone. In general, system specification involves identifying a few meaningful predictors (from a large enough set that is plausibly related to the response) and formulating a relation between them and the system response being modeled. For systems where physical relationships are less apparent, and sufficient observational records exist, a range of statistical alternatives have been investigated as a possible way of specifying the underlying form. Here we introduce partial information (PI) as a new means for specifying the system, its key advantage being the relative lack of major assumptions about the processes being modeled in order to characterize the complete system. In addition to PI which offers a means of identifying the system predictors of interest, we also introduce the concept of partial weights (PWs) which uses the identified predictors to formulate a predictive model that acknowledges the relative contributions, predictor variables make to the prediction of the response. We assess the utility of the PI‐PW framework using synthetically generated data sets from known linear, nonlinear, and high‐dimensional dynamic yet chaotic systems and demonstrate the efficacy of the procedure in ascertaining the underlying true system with varying extents of observational evidence available. We highlight how this framework can be invaluable in formulating prediction models for natural systems which are modeled using empirical or semiempirical alternatives and discuss current limitations that still need to be overcome.


Schools with pesantren basis now is for integrating public education with pesantren. This study examines the pesantren-based PAI curriculum model integrates the curriculum into a national standard PAI curriculum. This is a head master effort as a leader who conducts two curriculums that is national and pesantren curriculum. The aim is in order to create a strong and superior generation in the fields of IMTAQ, science and technology development, and morality. PAI collaborated with pesantren subjects, is in accordance with national and pesantren curriculum. Pesantren curriculum is including Nahwu Shorof, Arabic, SKI and Kedaruluman, Aqidah-Akhlak, Fiqh, Qur'an Hadith, Tajwid. All of these are combined with descriptions of the books in the pesantren. Besides religious application programs including Reading Al-qu'an, such practices activites as tahlil, istighosah and dhuha. From the research results, the researcher recommends the Religion and national education ministry to provide training for teachers about the model integrated learning, especially for the institutions under the pesantren, then the school principals have to strive to integrate the pesantren curriculum into formal schools.


Solid lubricant coatings have received considerable research attention in space applications owing to their remarkably improved tribological characteristics. But their service life is seriously restricted by the harsh environment, such as high vacuum and abrasive wear. In this paper, a novel design of carbon-based multilayer (MoS2/DLC multilayer) coatings was reported to clarify the friction and wear behavior in high vacuum conditions with and without simulated lunar-dust (SLD). Compared with pure DLC or MoS2 coatings, the multilayer coating showed excellent tribological performance with a low friction coefficient of 0.02 and a wear rate of ∼6.5 × 10−6 mm3 N−1 m−1. What is particularly interesting is that the wear volume of MoS2/DLC multilayer coatings with the increase of time is in accordance with the Archard linear law, regardless of the condition with or without SLD. Moreover, the surface morphology and composition of wear tracks and scars reveal that the long life of carbon-based multilayer coatings cannot be explained solely by excellent mechanical performance, and is also attributed to the formation of ridge layers as third body reservoirs and a tribo-induced composite transfer layer containing SLD nanoparticles and coating materials.


This paper describes the novel imaging of SAR phenomena produced from vibrating targets with multipath effects. It has been established, through numerical SAR experiments, that different physical mechanisms interact to produce new artefacts. The computations demonstrated that the edges of a dielectric medium can act as a source for multipath effects to emanate from, leading to the hypothesis that SAR artefacts can arise from through-wall SAR imagery. This deduction and mechanism of origin were validated through several experimental measurements, undertaken at Cranfield University's Antennas and Ground-based SAR laboratory, yielding results that closely match those predicted.


Objective: to assess short-term and long-term outcomes of right hemicolectomy with extensive lymph node dissection using the experience of one clinic.Materials and methods. This retrospective study analyzed data from a prospectively collected database containing information on all patients with right-sided colon cancer that underwent laparoscopic right hemicolectomy with D3 lymph node dissection between 2013 and 2018. We estimated intraoperative blood loss, surgery duration (taken from anesthetic records), frequency of postoperative complications, length of in-hospital stay, duration of lymphorrhea, time to gastrointestinal recovery, integrity of the mesocolon, number and location of removed lymph nodes.Results. A total of 50 underwent laparoscopic right hemicolectomy with D3 lymph node dissection. No cases of surgical conversion were registered. Median surgery duration was 185 min; median blood loss was 30 mL. No postoperative mortality was observed in the study cohort. Twelve (24 %) patients had postoperative complications; 2 (4 %) patients underwent repeated surgery. Median number of lymph nodes examined was 26; high-quality specimens (G ) were obtained in 48 (96 %) patients. At a median follow-up of 19.5 months, 2 (4 %) patients had disease progression (developed liver metastases).Conclusion. Our results confirm safety of laparoscopic approach for right colon resection with D3 lymph node dissection


The trend of customer today in many industries is in customized products. The implication to this is in the production floor especially in the assembly plant, where the flow of materials must be managed to ensure that every machine or workstations are supplied with complete materials and volume (quantity), in the right time, so that throughput can be achieved as scheduled. This study is being conducted in a hospital bed industry which uses a special workbench to assemble the beds. This papers outlines the efforts taken to measure production floor performance in the company. The main objective of the study is to define key performance indicators (KPI) of hospital bed production and measures the production floor performance. Using systematic approach to define the main KPIs, resource production capability, valid product definition, production performance as production scheduled and operational performance. Using break down tree analysis for each main KPIs, detail KPIs can then be deploy with the weights of all the KPIs. Based on those KPIs, an instrument(questionnaire) to capture all data need to measure production floor performance was developed. This instrument can be deployed in the production floor to be monitored by the supervisors, and production floor manager. The feed back analysis used value engineering method. The result for production capability, product design definition, production schedule and group production performance showed a level of 3.06, 2.75, by 3.33 and 2.36 for each group performance, and a total performance of 2.92 from a scale of 5. The total level of production performance is below average and the group contributor achieved performance level of below average and average only. This level is far from excellent level performance which require improvement to achieve the level of world class company.


Features of structure and history formation of abyssal hills of North-Western Pacifi c plate are considered by data of high (120–150 Hz) frequency SCP (seismic continuous profi ling), CDP1 profi le and Meso-Cenozoic, sedimentary-trap cover seismostratigraphy. It was established that asymmetric tectonic and more symmetric injected hills of Late Cenozoic (Neogene-Quaternary) age and without signs of volcanic activity are dominated among them. Tectonic hills are connected with Neogene-Quaternary glide faults of Layers 1–4, injected hills – with rootless, probably granitic, protrusions from Layer 4. The combination of tectonic and injective basis of inherited development from previous peneplanation epoch displayed in some hills structures. Some hills of other structure, origin and age also described: young gas volcano cone, Late Mesozoic volcanoes, and mini cones of black smokers.


Laparoscopic adrenalectomy has the advantage of reduced blood loss, early convalescence, and shorter hospital stays. Retroperitoneal laparoscopic approach was first demonstrated by Mercan et al. in 1995 and is easier for adrenal pathologies. Adrenal-preserving surgeries may prevent adrenal insufficiency from developing over long time. There are many studies in the literature which have compared the appropriate approach and the extent of resection for the functional adrenal tumor. But it remains unclear which is the optimal option. Here we present a video of laparoscopic partial adrenalectomy by a retroperitoneal approach in a patient with primary hyperaldosteronism.


Objective To investigate the effect of a selective epidermal growth factor receptor(EGFR) ZD1839 on cervical carcinoma cells.Methods The effect of ZD1839 on cervical carcinoma cells(Siha,Hela) was determined by MTT assay.The effect of ZD1839 combined with cisplatin(DDP) on cervical carcinoma cells was also evaluated.Burgi formula was adopted to analyze combination effect.The distribution of cell cycle and cell apoptosis rate were analyzed by flow cytometry.Results The proliferation of cervical carcinoma cell lines(Siha,Hela) was inhibited by ZD1839,and the effect was dose-dependent.The value of IC_(50) for the effect of ZD1839 on cervical carcinoma cell lines(Siha,Hela) was(1.48)μmol/L and(2.67)μmol/L respectively.ZD1839 could enhance the effect of DDP on Siha and Hela cells.The Q values by Burgi formula were(1.06)±(0.03) and(1.13)±(0.01) respectively.ZD1839 could change cell cycle and the rate of apoptosis.Conclusion ZD1839 inhibits the proliferation of cervical carcinoma cells and enhances the effect of DDP.ZD1839 induces cervical carcinoma cells(Siha,Hela) cell cycle arrest in the G1 phase and induce apoptosis.


ABSTRACT Recent research has shown that landscape-level changes, namely habitat loss and fragmentation, can play an important role in determining the distribution of species across a variety of ecological systems. However, the influence of these large-scale factors in relation to small-scale factors, such as local vegetation structure or composition, is poorly understood. We used Bachman's Sparrow (Peucaea aestivalis) as a surrogate species to measure the relative importance of local vegetation and large-scale habitat distribution in the Onslow Bight region of North Carolina, USA. We conducted repeated point counts at 232 points within 111 habitat patches between April 10 and July 20, 2011. We then fit a series of single-season occupancy models, including both local and landscape-level predictors, to identify those that best explained the distribution of Bachman's Sparrows. We documented a strong response to vegetation characteristics best maintained via prescribed fire, but the most influential predictor of Bachman's Sparrow occupancy was the amount of habitat within 3 km. Specifically, the probability of Bachman's Sparrow occurrence was close to zero in landscapes comprised of <10% habitat, regardless of local vegetation conditions. Our results illustrate the strong influence of habitat loss on Bachman's Sparrow and likely on other members of this community, many of which are of high conservation concern.


The paper concerns a new method of diagnosing and monitoring 3D printing processes based on measurements of kinematic parameters describing the movement of the 3D printer head. The aim of the research was to create a neural network model using unsupervised learning methods, whose task is to map signal characteristics (accelerometer and gyroscope data) to latent space. The measurement of significant quantities describing the kinematics of printer head movement was carried out during the execution of the given 3D print. The proposed latent artificial neural network algorithm was implemented in the microprocessor of the IMUMETER measuring device and tests were carried out during which the measuring system collected data and the neural network model mapped the features in such a way that it separated signals with anomalies from typical signals. The results allowed for the mapping of features and the analysis of the occurrence of anomalies on a sample printout of a wing section model for testing in a wind tunnel.