Neuromodulation is a key process determining the function of central neurons. The brain extracellular fluid contains numerous neuromodulatory substances (neuromodulators), but how they collective influence neuronal activity in vivo is not known. This thesis work attempts to shed light on this issue by examining the neuromodulatory influence of human cerebrospinal fluid (hCSF) on neurons in rat and mouse hippocampal brain slices, using a matched artificial cerebrospinal fluid (aCSF, devoid of neuromodulators) as control. The methodology comprises intracellular and extracellular recording techniques and, to lesser extent, biochemical and histological procedures. In paper I we examine the effect of hCSF on CA1 pyramidal cells. We find that hCSF induces in vivo-like properties in these neurons, powerfully boosting spontaneous action potential firing, depolarizing the resting membrane potential and lowering the action potential threshold. In paper II we record from GABAergic fast-spiking and non-fast-spiking interneurons in the CA1 hippocampus and show that hCSF excites both types of neurons through mechanisms involving reductions in afterhyperpolarization amplitudes and action potential threshold. Finally, in paper III, we show that hCSF induces spontaneous network gamma oscillations in the CA3 stratum pyramidale, via a cholinergic mechanism, and enhances electrical theta resonance in CA1 pyramidal cells through potentiation of two separate voltage-gated conductances. Taken together, the findings in this thesis project suggest that neuromodulators in brain extracellular fluid significantly contribute in shaping neuronal activity in vivo.


This paper discusses the stereotypes and prejudices against a certain social group as limiting factors for the individual choices of people belonging to the respective group, which consequently lead do discrimination, stigmatization, hate speech and eventually to bias-motivated violence. The analysis is conducted on the basis of the case law of the European Court of Human Rights.
In this context, the analysis of the case law and the findings of the Court are given special place with regard to the stereotypes in cases of discrimination on the grounds of sex and gender, ethnic and racial background, disability, status of HIV positive people, sexual orientation, religion and belief. On the other hand, the paper analyses the religious, ethnic and homophobic prejudices which are the underlying cause of hate crimes.


Dstl has sponsored the development and use of several campaign level models of military operations. The models are required to provide insight into force assessment, procurement decisions of future concepts and for investigations into potential doctrinal developments. COMAND is a theatre level representation of the naval air (maritime) campaign. COMAND also contains a simple representation of the joint force influence on the land campaign. COMAND is a stochastic model, and runs on a desktop PC under Windows NT. The key to COMAND is the representation of command and control aspects of the campaign, with representation of sensor and communication systems, information flows, command decision making, combat and perception of the battlefield. As part of the process to establish the validation status of COMAND, an attempt was made to replicate the 1982 Falkland Islands Campaign. This attempt was largely successful, and provided much information on the strengths and weaknesses of the model.


This document defines the types of OGF documents and the development and review processes for each type. This document obsoletes GFD-C.1 [CATLETT] and replaces it as the description of OGF community practice surrounding the document series. The process reflects several years of experience with OGF document publication, and borrows heavily from the Internet Engineering Task Force Request for Comments document process.


Based on natural language processing technology, cognitive psychology theory and word problem teaching methods, word problem auto-solving and intelligent tutoring technologies have become hot issues of research in recent years. However, since word problems are described by natural language, the number of resolved problems is limited. You-sentence 1 is a common sentence in Chinese word problems and the method of understanding it is easily extended to other types of sentences. This paper proposes an algorithm for autounderstanding and auto-solving Yousentence word problems and develops a system based on it to see whether the algorithm works.


batches of the propolis adjuvant combined inactivated vaccine against both Newcastle disease were producted with the Newcastle disease virus colon 30 and egg drop syndrome virus EDS76,AV127 strain which was harvested from the infected expermentally chicken embryos and duck embryos.No abnormal signs were observed in 3 6 weeks old chickens injected with 1 mL of the vaccine(i.e. 2 immune dose).There was no influences on the body weight again in the following 1 15 days after injected with 0.5 mL vaccine(i.e. one immun dose) at the one day old.Vaccination of the 3 6 weeks old chickens with the vaccine induced the hemagglutination inhibition(HI) antibody titer to ND in geometric mean 4.8 9.8 log2 and to EDS76 in geometric mean 6.0 11.8 log2.Their 50% protective dose per vaccine dose(PD 50 /dose) were ≥127, ≥131 and≥127, respectively.


Load balancing is a way to spread tasks out over multiple resources. By processing tasks and directing sessions on different servers, load balancing helps a network avoid annoying downtime and delivers optimal performance to users. There are virtual load balancing solutions that work in a manner similar to virtual applications or server environments. There are also physical load balancing hardware solutions that can be integrated with a network. The method used depends entirely upon the team implementing the solution and their particular needs. Network Load Balancing (NLB) is a clustering technology offered by Microsoft as part of all Server and Windows Server 2003 family operating. NLB uses a distributed algorithm to load balance network traffic across a number of hosts, helping to enhance the scalability and availability of mission critical, IP -based services, such as Web, virtual private networking, streaming media, terminal services, proxy and so on. It also provides high availability by detecting host failures and automatically redistributing traffic to operational hosts. This paper describes the detailed architecture of network load balancing, various types of addressing and the various performance measures.


Recent studies have suggested that Helicobacter pylon and non-steroidal anti-inflammatory drugs (NSAIDs) are capable of various mechanisms in the gastroduodenal mucosa. are their acid activity, the effect of H pylori on gastric acid secretion its hypergastrinaemia. H pylon and gastric mucosal prostaglandins, platelet


The research explains the form of local wisdom of Bugis culture as a cultural value that characterizes the Palopo people. The local wisdom developed in Palopo City is in line with the pluralistic Palopo culture developing in Indonesia. Palopo people has local wisdom values such as humanizing. These values are always preserved so that they become the glue of religious harmony in Palopo City. The type of this research is ethnography. The research findings show that knowledge and understanding of the cultural traditions of society that contain pluralism allow students to suspend suspicion or even wholly disappear negative things that students have understood about other religions. The concept of pluralism is seen from implementing the cultural philosophy in Palopo, namely Sipakatau, Sipakalebbi, and Sipakaingge. Two universities, IAIN Palopo and Andi Djemma University practice the local wisdom values. The results shows that personally, students who were actively involved in the implementation of local wisdom education felt that they had experienced significant changes. In the aspect of faith, they are increasingly convinced of their religion while still providing adequate space for a good and correct assessment of the truth of the teachings of other religious and cultural beliefs.


A novel polysulfone was easily synthesized by alternating copolymerization of norbornene with sulfur dioxide (SO2) via free radical copolymerization and coordination copolymerization. Compared with other olefin derivatives, norbornene is a cyclic olefin having a larger steric hindrance, which is easily copolymerized with SO2, and the obtained poly(norbornene sulfone)s have excellent thermomechanical and optical properties. The effect of the different polymerization methods on the copolymerization reaction was analyzed in detail. The results suggested that different polymerization mechanisms exist in the different polymerization methods and affect the thermal stability and optical properties of the polysulfone. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 44534.


H E 1820S opened a period of nearly 50 years of expansion of mining in Chile. During that decade, Chile's mines produced a yearly average of 2.7 million kilograms of bar copper. Production increased by nearly 70 percent over the next decade, and reached an annual average of more than 9 million kilograms by midcentury. Copper production in all its forms continued to climb, approaching 8o million kilograms a year in the 1870s.1 Yet producers seemed far fiom enthusiastic about their prospects. El Copiapino, the northern mining zone's major newspaper, cautioned that "the miner who does not have the good fortune to strike it rich within one year of starting work, faces ruin... 2"2 Indeed, the naysayers proved correct as copper production gradually weakened. By the 189os, total yearly production averaged less than 30 million kilograms. Unable profitably to exploit lower-content ores, Chilean producers saw the industry slip from their grasp. By the end of World War I, more than 87 percent of Chileani copper production was in the hands of U.S. investors.3


The metadata service of the Ursa Minor distributed storage system scales metadata throughput as metadata servers are added. While doing so, it correctly handles metadata operations that involve items served by different metadata servers, consistently and atomically updating the items. Unlike previous systems, it does so by reusing existing metadata migration functionality to avoid complex distributed transaction protocols. It also assigns item IDs to minimize the occurrence of multiserver operations. Ursa Minor's approach allows one to implement a desired feature with less complexity than alternative methods and with minimal performance penalty (under 1% in non-pathological cases).


By a finite difference method, flows around cylinders with rectangular cross sections of various width-to-height ratios of 0.4 to 8 have been computed in the range of Reynolds numbers of l00 to 1200. We have successfully simulated some interesting phenomena whereby flow around the cylinder of the B/H ratio of 2 changes to a fully separated flow at a Reynolds number of 800, while for the cylinder of the B/H ratio of 2.8, a fully separated flow changes to an alternate reattachment one at a Reynolds number of 1200 with the lapse of time, two components with different Strouhal frequencies appear in a flow field around the cylinder of the B/H ratio of 6 at a Reynolds number of 800, and the flow pattern critically changes when the B/H ratio is 2.8 and 6 at Reynolds numbers of 500 to 1200. It is clarified by a numerical simulation that the component with a high Strouhal frequency is induced by vortices separated from the trailing edges and that the low Strouhal component is due to the oscillation of flow over the side walls accompanied by a movement of separation bubbles. Finally, the computed results of flow patterns, base pressure, drag force and Strouhal number show a good agreement with the experiments.


Social geography cannot be confined to a theoretical dimension, however necessary: it is expected to play an active role, to encourage encounters with social actors and stakeholders, to take on a dimension of public engagement. Even in Italy this dimension is increasingly important, as universities are placing a growing value on their so-called third mission. Social geography must then address the fundamental issue of participation and its techniques. In doing so, those who graduate in geography will also be able to claim an essential role in the management of decision-making processes and participatory planning. This paper explores some methods and approaches that younger geographers can use to build the 'toolbox' of their future profession, looking at a case study from the city of Palermo.


Objective To evaluate the relationship between the change of lipid and prostacyclin and myocardial infarction area inpatients with acute myocardial ionfarction(AMI). Methods This study tested lipid and prostacyclin of. Patients with AMI from may, 2002 to December, 2004, and analyzed the correlation between lipid and prostacy clin and infarction area. Results TC、TG、LDL、ApoB and TXA2 are the risk factors that foresee AMI, The area of infarction is related to prostacyclin, but irritated to lipid.


One of the most important things in restructuring current system is to clarify business specification which are implemented in the current system. Reverse engineering technology, which extracts reusable business specification from a system, is very effective for this purpose. We have developed DORE (Data Oriented Re-Engineering), a re-engineering methodology for system restructuring, and tools that support reverse engineering. By using these methodology and tools, it becomes possible to extract business specification which should be implemented in the new system, from the current system. In this paper, we present the re-engineering methodology and tools, and introduce a case study in Kawasaki Steel Corporation, in which those methodology and tools are used.


The invention provides a power control parameter transfer method, a device and a terminal, the method comprises the following steps: a base station configures parameters for the terminal through a signal of a radio resource control layer, wherein, the parameters at least comprise: a temporary identifier of a power control wireless network, a downlink control information format and a power controlindex; and a terminal obtains a corresponding power control command on a downlink physical control signal channel according to the configured parameters. The method is characterized in that the base station configures the corresponding downlink control information format for the terminal which configures the same temporary identifier of the power control wireless network. The technical scheme canavoid the problem that the terminal erroneously interprets the content of power control sent by the base station due to the configuration errors of the base station, thereby causing the failure of power control.


Nutritional manipulation and genetic selection for egg size and production may lead to changes in egg components. This experiment was carried out to analyze the egg structure parameters of eggs produced by Hisex Brown laying hens fed with diet with different supplements inclusion. The intensity of egg production was significantly higher in the groups fed with enriched feed with iodine (90.00%), vitamin E (90.00%) and selenium (91.98%), and significantly lower in the group fed with DHA inclusion feed (76.00%) in respect to the control group (82.00%), confidence interval of 95%. Concerning diet supplemented with selenium and diet supplemented with vitamin E, the egg yolk weight was statistically different compared with the control group (confidence interval of 95%). The yolk weight averaged 1.80 g and 1.29 g more than yolk weight in the control eggs, respectively. The egg shell weight was statistically different in diet enriched with iodine compared with the control. The egg shell weight averaged 1.48 g less per egg for the eggs enriched with iodine with 17.45% less underweight than the control eggs. Enriched eggs offer consumer a variety of value-added options for their egg purchase. Although enriched eggs may provide consumers with a specific quality attribute or healthful ingredient, they do not appear to provide quality and value in a traditional sense as defined by the standards of quality and grade.


This article gives some measures of fostering the students' innovative ability in the course of " Principle of Machinery ",and expresses the author's idea and exploration about it,they include: developing the innovation interaction,aggrandizing the teaching specialties,cultivating students' ability of solving problems by computer and creating a good innovation environment.Experience has proved that they were effective ways of fostering the students' innovative ability.


Abstract Purpose: The aim of this work is to determine if a relationship exists between thyroid dose and incidence of primary hypothyroidism (PH) in children undergoing craniospinal irradiation (CSI). Methods: A total of 22 patients received CSI with evaluable thyroid dose information. All patients received concurrent chemotherapy and 21 patients (95%) received adjuvant chemotherapy. Median follow-up was 42.9 months. Results: The incidence of PH in our cohort was 59% at a median time after radiotherapy of 3.5 years (range: 8 months to 7.5 years). Mean thyroid dose appeared to best predict for PH, with a median of 2080 cGy for patients with PH versus 1736 cGy for children without PH (p=0.057). There was no association between the rate of PH and sex, age, CSI dose, minimum thyroid dose and maximum thyroid dose. Conclusions: A relationship may exist between the mean thyroid dose and incidence of PH in patients undergoing CSI. Thus, new strategies to protect the thyroid gland may be warranted.


Preface ix Acknowledgments xvii Chapter 1: Overture: Sensibility in the Age of Slavery 1 Chapter 2: Intersections: Taste, Slavery, and the Modern Self 50 Chapter 3: Unspeakable Events: Slavery and White Self-Fashioning 97 Chapter 4: Close Encounters: Taste and the Taint of Slavery 145 Chapter 5: "Popping Sorrow": Loss and the Transformation of Servitude 188 Chapter 6: The Ontology of Play: Mimicry and the Counterculture of Taste 233 Coda: Three Fragments 282 Notes 287 Bibliography 321 Index 353


Electronic commerce is growing vigorously at present.It is the modern means of entering new developing marsket, catching customer information,strengthening communications with outwards,improving insde efficiency,building close relation between supply and meraketing, economizing operate-cost.It has changed the traditional commercial mode, and promisingly will become the main management styles of enterprises in future's business society.E-commerce exerted an important influence on the principles of traditional accounting check and calculate,on the way of settlement and the procedure of accounting check and calculate etc.


Monolithiation of the chiral amine (S)-N-(α-methylbenzyl)allylamine, in the presence of the strong Lewis donor solvent hexamethylphoshoramide (HMPA), results in pale yellow crystals which have been crystallographically analysed revealing the structure of the complex to be an asymmetriccisoid dimer {(S)-α-[PhC(H)CH3](CH2CH=CH2)NLi·HMPA}2. Variable-temperature NMR studies show this complex can undergo a thermally induced rearrangement to a 1-azaallyl complex at ca. 90 °C. Attempted dilithiation of the chiral amine at the N and vinylic C centres with nBuLi and HMPA results in competitive reduction of HMPA to give crystals of the lithium dimethylamidophosphite, structurally authenticated as the hexamer [(Me2N)2POLi]6, in which the Li cation is bonded preferentially to the O centre and not P. The effect is a reduction in the oxidation state of the P centre from (V) to (III), which is supported by ab initio calculations showing the crystal structure to represent the most thermodynamically stable of the possible isomers. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)


The Australian finger lime is a unique citrus species that has gained importance due to its unique fruit characteristics and perceived tolerance to Huanglongbing (HLB), an often-fatal disease of citrus trees. In this study, we developed allotetraploid finger lime hybrids and cybrids by utilizing somatic cell fusion techniques to fuse diploid 'OLL8' sweet orange or 'Page' tangelo callus-derived protoplasts with finger lime (FL) mesophyll-derived protoplasts. Six somatic fusions were regenerated from the 'OLL8' + FL fusion, while three putative cybrids were regenerated from the 'Page' + FL fusion. Ploidy levels and nuclear-expressed sequence tag derived simple sequence repeat (EST-SSR) markers confirmed the somatic hybrid production, and mitochondrial DNA primer sets confirmed the cybrid nature. Several trees produced by the somatic fusion remained HLB negative even after 6 years of growth in an HLB-endemic environment. Pathogenesis related (PR) and other genes that are often upregulated in HLB-tolerant trees were also upregulated in our somatic fusions. These newly developed somatic fusions and cybrids could potentially be used as breeding parents to develop the next generation of improved HLB-tolerant rootstocks and scions.


This article has analyzed the influence of postmodern practices on the development and functioning of nation states, their culture and identity. It is shown that postmodernism is largely determined by the processes of globalization as the current defining civilizational progress, the content of which is the growing interconnection and interdependence of national economies, political and socio-cultural systems, as well as the identity of universalistic practices of regulating the activity of subjects of world-system relations in different spheres of being.
It was found that one of the problematic consequences of postmodernism is the radical transformation of traditional structures and principles of self-identification, both collective and personal wherever they happen, and whatever the institutional, cultural layers of society and patterns of behavior affect people. Close coexistence and even interpenetration of completely different, sometimes mutually exclusive, and sometimes simply disjointed value scales lead to total relativization of everything and everybody when even personal and collective identities lose the quality of metaphysical constants and are perceived as an unfinished project. That is why a person of the postmodern age is deprived of self-certainty. Therefore, there is a great need to rethink the content and consequences of postmodern practices of blurring traditional identities and the emergence of new ones, the role of the state in preserving and protecting the values, contents, ideals, cultural models and language that shape and reproduce the nation.
It is concluded that in post-totalitarian states of the European space (including Ukraine), processes of globalization and post-modern practices create two opposite tendencies. On the one hand, globalization unifies, internalizes and westernizes all aspects of society. On the other hand, in the way of bringing the elements of modern democracy into the life of the post-totalitarian state, globalization stimulates the processes of cultural and spiritual revival and the desire to form the collective «We», affirm its identity and individuality through consolidation around a common history, language, culture, values and orientations, life strategies. In Ukraine, it is also a consolidation of the efforts of all its citizens to repel Russian aggression, protect the sovereignty and independence of the state, integrate into European and Euro-Atlantic structures, achieve well-being for all citizens. Ukraine, as the newest unfinished civilization project, has all prospectives of avoiding the pitfalls of both «melting pot» and multiculturalism, as well as postmodern problems, since most of them have not yet attained a broad realization in its territory.


A programmable logic controller (PLC) is a digital computer used for automation of electromechanical processes, which is a type of computer family and they have commercial and industrial applications. The development of programmable logic controller (PLC) makes it possible to do the required changes to the program without changing the electrical circuit connections. Two separate design projects aided with PLC have been designed to deal with practical process and machinery problems. In addition to that, these projects have been designed for a PLC course of two years in electrical technology institution. The PLC programs (Software SIMATIC 200 Step 7 Micro/Win16) have been loaded, cooperated with Educational Delorenzo Italian Company with a siemens type process (CPU 216). Moreover this software has been implemented for training at the Technical Industrial Institute at Haddah and has been found to be applicable and easy to use with high accuracy.


Size reduction is a key issue in the development of contemporary integrated photonics. This thesis is mainly devoted to study some integrated photonic components in sub-wavelength or nanometric sca ...


William H. Leonard William H. Leonard is an associate professor at Louisiana State Univ., Baton Rouge, LA 70803, where he is appointed jointly in the Dept. of Zoology and Physiology and in the Dept. of Curriculum and Instruction. He earned his B.A. and M.A. in Biology at San Jose State Univ. and his Ph.D. in Biology Education at the Univ. of California at Berkeley. He was a high school biology teacher in San Jose, California for 13 years and a member of the biological sciences faculty at the Univ. of Nebraska, where he received the Amoco Distinguished Teaching Award in 1982. Leonard has published more than 40 articles in science teaching journals, including ABT, Science Education, Journal of Research in Science Teaching, Journal of College Science Teaching and The Science Teacher. He authored a biology laboratory textbook, published by Burgess, Co. An active member of NABT, Leonard is coordinator of Region VI and chair of the Scientific Integrity Committee.


In the article there are presented the results of electrodynamic simulation of tri-band microstrip antenna characteristics (MSA), designed to work in the radio receiver GLONASS/GPS. There are considered the performance issues in a single antenna implementation with a single point of supply. The performance of the antenna in the range of L1, L2, L3/L5 is investigated.


Sepsis is caused by infection of systemic inflammatory response syndrome (SIRS), further development will evolve into severe sepsis, sepsis shock, and as a result of multiple organ dysfunction syndrome (MODS). It is the most common diseases and the leading causes of death of the critically ill patient.Thus, it is a big challenge of the intensive care unit (ICU). At present, the diagnosis relies mainly on the nonspecific physiological conditions and culture of pathogen detection.This leads to a clear diagnosis and treatment of delayed and the overuse of antibiotics.Sepsis needs new biomarkers that can help treatment decisions and adding information screening, diagnosis, risk stratification, response to treatment and monitoring.This article discusses some of the more clinical research and the latest biomarkers.

Key words:
Sepsis; Biological markers; Diagnosis


The associated production of a single-top with opposite-sign same-flavor (OSSF) di-leptons, pp → t(cid:96) + (cid:96) − and pp → t(cid:96) + (cid:96) − + j ( j = light jet), can lead to striking tri-lepton pp → (cid:96) (cid:48) (cid:96) + (cid:96) − + X and di-lepton pp → (cid:96) + (cid:96) − + j b + X ( j b = b -jet) events at the LHC, after the top decays. Although these rather generic multi-lepton signals are flavor-blind, they can be generated by new 4-Fermi flavor changing (FC) u i t(cid:96)(cid:96) scalar, vector and tensor interactions ( u i ∈ u, c ), which we study in this paper; we match the FC u i t(cid:96)(cid:96) 4-Fermi terms to the SMEFT operators and also to different types of FC underlying heavy physics. The main backgrounds to these di- and tri-lepton signals arise from t ¯ t , Z +jets and V V ( V = W, Z ) production, but they can be essentially eliminated with a sufficiently high invariant mass selection on the OSSF di-leptons, m min (cid:96) + (cid:96) − ( OSSF ) > ∼ 1 TeV; the use of b -tagging as an additional selection in the di-lepton final state case also proves very useful. We find, for example, that the expected 95% CL bounds on the scale of a tensor(vector) utµµ interaction, with the current ∼ 140 fb − 1 of LHC data, are Λ < ∼ 5(3 . 2) TeV or Λ < ∼ 4 . 1(2 . 7) TeV, if analyzed via the di-muon µ + µ − + j b signal or the eµ + µ − tri-lepton one, respectively. The expected reach at the HL-LHC with 3000 fb − 1 of data is Λ < ∼ 7 . 1(4 . 7) TeV and Λ < ∼ 2 . 4(1 . 5) TeV for the corresponding utµµ and ctµµ operators. This should be compared to the current bounds of Λ < ∼ O (1) TeV on both the ut(cid:96)(cid:96) and ct(cid:96)(cid:96) operators from LEP2 and from pp → t ¯ t followed by t → (cid:96) + (cid:96) − j . We also study the potential sensitivity at future 27 TeV and 100 TeV high-energy LHC successors, which, for the ut(cid:96)(cid:96) operators, can reach Λ ∼ 10 − 40 TeV. We furthermore discuss the possible implications of this class of FC 4-Fermi effective interactions on lepton non-universality tests at the LHC.


The strain energy density in epitaxial overlayers depends strongly on the substrate's surface orientation. The affect of a growth orientation dependent strain energy contribution to the phase stability was studied by growing overlayers of metastable, semiconducting a-Sn films on the (100) and (111) surfaces of Cd 0.8 Zn 0.2 Te substrates. On the (100) surface the α-phase of Sn remains stable for coverages up to and beyond 125 ML. On the (111) surface though, the Sn overlayer shows metallic behavior from a partial α→β phase separation for coverages lower than 100 ML. Static calculations using the stress-strain relationship bear out these experimental results by showing that the strain energy density for the (111) growth direction is 38% larger than for the (100) direction.


Two-color zero kinetic energy (ZEKE) photoelectron spectra due to the cation D0 states of thioanisole and its van der Waals complexes with argon (thioanisole−Ar and −Ar2) in a supersonic jet are reported for the first time, together with mass-selected REMPI (resonantly enhanced multiphoton ionization) spectra associated with their S1 states. For bare thioanisole, the adiabatic ionization energy (Ia) is 63 906 ± 3 cm-1 and the S1 origin is located at 34 506 ± 1 cm-1. Low-frequency vibrational progressions due to the excitation of the CH3S torsion (94 cm-1) are observed in the ZEKE photoelectron spectra. A series of hot bands showing a large anharmonicity is observed in a REMPI spectrum, indicating that the CH3S torsional frequency is 68 cm-1 in the neutral ground state. An ab initio 6-311G** calculation gives a torsional barrier of 530 cm-1 along the S−C(sp2) bond and a minimum energy for the CH3 group rotated 90° from the aromatic plane. Intensive Δv = 0 ionization transitions are observed in the ZEKE pho...


Many investigations of the preservation of soil organic carbon (SOC) in permafrost regions have examined roles of geomorphology, pedogenesis, vegetation cover, and permafrost within particular regions. However, it is difficult to disentangle the effects of multiple factors on the SOC in permafrost regions due to the heterogeneity in environmental conditions. Based on data from 73 soil study sites in permafrost regions of the eastern Qinghai‐Tibetan Plateau, we developed a simple conceptual model, which relates SOC to topography, vegetation, and pedogenesis. We summarized the dominant factors and their controls on SOC using 31 measured soil physiochemical variables. Soil texture explains approximately 60% of the variations in the SOC stocks for the upper 0–2 m soil. Soil particle size closely correlates to soil moisture, which is an important determinant of SOC. Soil salinity and cations are important factors as well and can explain about 10% of the variations in SOC. The SOC and total nitrogen (TN) stocks for the 1–2 m depths have larger uncertainties than those of upper 1 m soil layer. The vegetation, pH, and bulk density mainly affects SOC and TN stocks for the upper 1 m soil layers, while the active layer thickness and soil particle size have greater influence on SOC and TN stocks for the 1–2 m soils. Our results suggest that the soil particle size is the most important controller of SOC pools, and the stocks of SOC and TN are strongly effected by soil development processes in the permafrost regions of the eastern Qinghai‐Tibetan Plateau.


Background A total laryngectomy is a stressful experience for patients with laryngeal carcinoma. Total laryngectomy extends patients' lives at the expense of complete loss of natural voice, subsequent poor quality of life (QOL) and changes in social roles. This study aimed to assess these issues and assess QOL including the physical and the social well being (Communication, Swallowing, Social disruption, ongoing problems).


A study is made of the waves which may occur at the interface of two fluids and which arise from an interaction between the two lowest adjacent harmonics of the motion. The problem is studied by reformulating it, via a conformal mapping transformation, into a pair of coupled nonlinear functional differential equations which are invariant under the action of the group [Formula: see text] The classical method of Lyapunov–Schmidt is then employed to replace this formulation by a pair of algebraic equations, known as the bifurcation equations. Throughout our analysis we impose a physical condition which essentially means that the densities and phase speeds in each fluid are approximately equal. This means that the bifurcation equations assume a cubic form rather than the quadratic form which they generically possess in problems of this type. The bifurcation equations are then analyzed by means of singularity theory by which means we are able to draw the solution curves of the system. A large variety of solution diagrams are found to exhibit such behavior as multiple primary bifurcations, secondary bifurcations and bifurcation from infinity.


We reconsider the discrepancy between theory and data in the momentum distribution of slow J/psi in B decays. Beside an update of the standard color singlet and color octet QCD components, we include the contribution from XY Z exotic mesons, and show that the residual discrepancy could be accommodated considering new XYZ mesons still unobserved.


Designing a distribution center (DC) is a complex process that consists of answering dozens of interrelated questions. From our perspective, the penultimate question is one of which picking methodology is optimal. To answer this question requires a full evaluation of picking methodologies in terms of their ability to meet the expected throughput requirements of the system. In manual picking systems, as throughput requirements increase, worker interaction and blocking increase as well. This implies that being able to estimate the amount of worker blocking in a system is critical to a design effort. Most of the prior research in this area addresses this point from an analysis perspective. In this paper we provide a design perspective based on the results from a structured simulation modeling study we conducted. We present our main result — a design rule ratio — as well as how this design rule ratio is used within a design process.


The implementation of the Whole-Peop1e Health-Building Plan,impact of old society and develop-ment in all respects of economic,culture and politics of society set a higher request to our sports personnel quality,Olympic Games will hold in Beijing especially.The article analyzes and thinks: According to the sports personnel training state of our province,we should strengthen and reform the content of courses and course sys-tem,further make training mode rational,enable the cultivation of the specialized personnel of sports to meet the needs of social development.


Protocol tittle: Study of BO-112 with pembrolizumab for colorectal or gastric/GEJ cancer with liver metastasis.Background: Gastric (GC), oesophagogastric junction (EGJC) and colorectal tumors (CRC) with microsatellite stability (MSS) are poorly responders to PD(L)-1 inhibition, due to low CD8+ T cell infiltration and PD-L1 expression. Therefore, modulation of the tumor microenvironment (TME) could increase disease control. In these tumors the presence of liver lesions is difficult to control because of the hepatic immune tolerance. Control of the hepatic disease could increase survival.BO-112 is a non-coding dsRNA agonist of TLR3, MDA5 and RIG-I which activates the innate and adaptative immune response, inducing apoptosis and immunogenic cell death, with a local and a systemic effect. A prior Phase I trial showed that the combination of pembrolizumab and intratumoral (IT) BO-112 has a good safety profile and encouraging activity. Study design: This is a single arm phase IIa trial to assess the efficacy of intrahepatic IT BO-112 and iv pembrolizumab in 3W cycles in patients with MSS CRC, GC or EGJ tumors. Up to 69 patients with at least one liver lesion and 2 prior lines for CRC and 1 for GC/EGJC will be enrolled. Primary endpoints: ORR and related TEAEs ≥ grade 3. Secondary endpoints: ORR (iRECIST), PFS, 6-months OS and safety. Exploratory endpoint: Changes in TME (PD-L1 expression and CD8+ T cell infiltration) from baseline to C2D1.Results: A total of 11 CRC and 7 GC/EGJC patients were enrolled since July 2020. This abstract focuses on the CRC patients´ biomarker expression. These patients had low PD-L1 CPS (combined positive score) expression and CD8+ T cell infiltration with a median value of 5 and 4%, respectively, in the TME at baseline. Following two IT BO-112 injections, an important increase in PD-L1 expression and CD8+ T cell infiltration was observed in 5 and 7 patients, respectively. PD-L1 CPS median value increased to 37.9 while CD8+ T cell infiltration median values raised to 12.9%.Conclusions: A meaningful increase in PD-L1 expression and CD8+ T cell infiltration was achieved in MSS CRC patients after one cycle of BO-112-pembrolizumab. Citation Format: Mariano Ponz-Sarvise, Elena Elez, Andres Munoz, Marc Van den Eynde, Antonio Gaetano Rampoldi, Alain Hendlisz, Hans Prenen, Mercedes Rodriguez, Maria Teresa Cano, Marya Chaney, Helena Escuin, Vanesa Pons, Marisol Quintero, Andres Cervantes. Phase IIa open-label clinical study of intratumoural administration of BO-112 in combination with pembrolizumab in subjects with liver metastasis from colorectal cancer or gastric/gastro-oesophageal junction cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr CT192.


Fig 1 . Map of Taylor Valley (showing Bonney, Hoare, and Fryxell Basins) and Wright Valley indicating the distribution of monitoring and experiment locations. Fig 7. Abundance and diversity of (A) major taxa and (B) eukaryotes in MCM Dry Valley Soils Fig 9. Changes in invertebrates and microbial mats in the Relict Channel Reactivation Experiment. (A) Habitat preferences of invertebrates in MDV streams. (B) Variation in abundance of invertebrates with distance from stream center. (C) Site map, site 1 is just below diversion. (D) Changes in invertebrate abundance in cyanobacterial mats and sediments between low flow and high flow summers. Fig. 4 . Conceptual model of climate driven presses and pulses in the MDV ecosystem. .


Purpose – This paper examines common features in local employees' behavior leading to problems in information security in foreign companies due to cultural differences between foreign managers and local workers. Design/methodology/approach – The investee countries of Russia, India, China, Brazil, Thailand, Venezuela, Malaysia and the East African Community are examined. Potential human-related problems developed using Hofstede's framework of culture and the results of previously conducted studies are examined and their linkage to cultural dimensions are validated using human behavioral heuristics. Findings – The problems of "Unintentional sharing of confidential information" and "Concealing faults made by friends" occur because of lower individualism of investee countries, while the problem of "Using any means to reach goals owing to high competition" occurs because of higher masculinity of the society. Originality/value – This paper has identified that human-related information security problems are linked to the investee countries' cultural dimensions through the behavioral patterns influenced by their cultures.


The research of vegetation restoration of freeway slopes lagging in the construction of freeway seriously in our country, it has restricted the progress of construction of the environmental landscaped roadway of the freeway greatly. The paper reviewed the main researched contents of the slope vegetation restoration of freeway in domestic and international, and summarize as five respects: technological research, plant choose and proportioning research, maintenance and management searches, vegetation community research and ecologic environment of freeway. By comparing, it has defined the current situation of research in vegetation restoration of freeway in our country, and has pointed out the weak point in each research field and main reasons of defeated restoration, which had offered the clear direction of study on the future research in the slope vegetation restoration.


Summary The redistribution of vertical ground reaction forces after surgically induced forelimb lameness was evaluated in five Greyhounds at the walk. Vertical ground reaction forces were measured by force plate analysis before, three days, and seven days after a craniolateral approach to the shoulder was performed unilaterally in each dog. At day # 3, peak vertical force was significantly decreased in the operated forelimbs and in the ipsilateral hindlimbs. Peak vertical force was significantly increased in the contralateral fore- and hindlimbs. The total peak vertical force applied to both forelimbs did not change, nor did the total force applied to both hindlimbs. At day # 7, peak vertical force in each of the four limbs had returned to preoperative levels. Results of this study document the redistribution of ground reaction forces (at the walk) between the four limbs in the dog after an acute, surgically induced forelimb lameness. The redistribution of ground reaction force was evaluated in five Greyhounds before and during forelimb lameness. Lameness was induced by a craniolateral approach to one shoulder in each dog. At day # 3 after surgery, peak vertical force was decreased in the operated forelimbs and ipsilateral hindlimbs. Peak vertical force was increased in the contralateral fore- and hindlimbs. The distribution of ground reaction force in the four limbs returned to preoperative values seven days after surgery.


We present the modeling on the modulation bandwidth and frequency chirp of transverse-coupled-cavity vertical-cavity surface-emitting lasers (VCSELs), which enable us to tailor the transfer function of intensity and frequency modulations thanks to an optical feedback effect. The simulation shows the 3-dB-modulation bandwidth can be doubled and the chirp can be reduced by a factor of more than three. These improvements could be explained by an increase in differential net gain in coupled cavities. The result shows a possibility of high-speed and low-chirp operations of transverse coupled cavity VCSELs for higher data rates and longer link lengths of single-mode fiber transmissions.


ABSTRACT

The purpose of this research is to test and analyze the influences of organizational culture, and transformational leadership on job satisfactionto impact employee performance. Using these variables, the usage of these variables are able to solve the arising problem within employee PT. Indonesia Power. Statement of this problem is how to increase employee performance.
The samples size of this research is 173 employee PT. Indonesia Power. Using the Structural Equation Modeling (SEM). The results show that organizational culture, and transformational leadership on job satisfactionto impact employee performance.
The effect of organizational culture onemployee performanceare significant; The effect transformational leadership onemployee performance are significant;The effect of organizational culture on job satisfaction are significant; The effect transformational leadership on job satisfactionare significant; The effect job satisfaction on employee performanceare significant.

Keywords: Organizational culture, transformational leadership, job satisfaction, andemployee performance.


A magnetic amplifying magneto-optical system (MAMMOS) which can expand a size of a small domain is one of the most promising candidates for ultra high density MO storage. Since the MAMMOS read-out consists of both domain expansion and collapse processes, it is important to understand the behavior of the aperture of the read-out layer in order to optimize laser power to achieve higher resolution. This paper reports on the aperture state and the read-out response, when an alternating magnetic field is applied. It is shown that domain expansion and collapse processes occur many times for every 0.4 p. m sized domain and that the shape of the read-out signal is very square. Additionally the number of times that the domain expands and collapses decreases by lowering laser power, which means that the aperture area becomes restricted. It was also confimled that both expansion and collapse times are much faster than the transient time of the circuit with a band width of 20 MHz, and it is independent of the read-out velocity.


Following the report of the breakthrough in the feasibility of practical application of Thin-Film Electroluminescent (TFEL) panels as solid state flat displays in 1974, a succession of efforts have been paid in the development of the production technologies of the panel, the implementation of the driver ICs of the panel, the assembling technique of the drive electronics, and what not; all aiming at the establishment of reliability and reproducibility.


This work presents a parallelization of a variant form of the Davidson algorithm. This variant allows the calculation of several eigenvalues including the case where the multiplicity is higher than one. In addition, new preconditioning strategies deliver better convergence. The disadvantage related to dense projected eigenproblems is diminished by representing the projected problems in an arrowhead matrix format. Theoretical timing estimates are developed. The parallel code is compared against these estimates.
Also a Newton-Multigrid method is presented. The new iterative method does not rely on Rayleigh quotient iterations, which makes the algorithm distinct from the standard inverse iteration. A multigrid solver is adopted to handle the nearly singular systems which arise from this class of algorithms. Numerical experiments are reported.


The design of a fast, high current interrupter capable of handling up to 5 amp is presented. Through small modifications even larger currents can be handled. The electronic interrupter is exceptionally versatile, has a short rise time, a variable output current, and a switching rate from 500 cycles per second to any longer period desired. Interruption periods as short as 1.6 microseconds were found to be quite practical. The high speeds, short rise times, and sizable currents make this interrupter an outstanding device compared to past efforts in this field. The applications of the interrupter in the field of electrochemical kinetics are illustrated through experimental work. Potential‐time traces for anodic dissolution of titanium were studied.


We define an operation on finite graphs, called co-contraction. By showing that co-contraction of a graph induces an injective map between right-angled Artin groups, we exhibit a family of graphs, without any induced cycle of length at least 5, such that the right-angled Artin groups on those graphs contain hyperbolic surface groups. This gives the negative answer to a question raised by Gordon, Long and Reid.


The purpose of this research was to reveal whether the Guidance and Counseling module designed for increasing the students' self-esteem had been proper in terms of content and appearance, and to describe the usability level of the Guidance and Counseling module to increase the students' self-esteem. This research applied ADDIE (Analysis, Design, Development, Implementation, and Evaluation) model. The subjects of the research consisted of 6 experts to see the properness of the module and 3 Guidance and Counseling teachers to see the usability level of the module. This research was conducted by trying out the product and through Focus Group Discussion (FGD). The data of the research were analyzed by using descriptive statistic analysis and inferensial statistic. Based on these results, in general, the prototype of Guidance and Counseling module designed for increasing the students' self-esteem had been proper and could be used by the Guidance and Counseling teachers to increase the students' self-esteem.


Cloud computing as a novel and entirely internet-based computing platform is emerging and its tenacious challenges become more vivid. A parallel genetic algorithm-based method for scheduling tasks with priorities is provided in this paper. The goal is to efficiently utilize resources and reduce resource wastage in cloud environments. This is achieved by improving the load balancing rate while better resources are selected to fulfill arrival tasks in a shorter time with lower task failure rate. To evaluate the proposed method, it is simulated using Matlab and compared with two existing methods, a hybrid Ant colony-honey method and a Round-Robin (RR) based load balancing method. The results show that the proposed method has 9% - 31% lower energy usage, 14% - 37% lower migration rate and 13%- 17% better Service Level Agreement (SLA) in comparison with the Hybrid and RR method.


The ability to manage diversity effectively is important not only in organizations but also in the classroom. This article describes an instrument for assessing instructor cultural competence and the process used to develop the instrument. Using the critical incident technique, the authors developed a situational questionnaire that assesses behavioral intentions in response to classroom diversity incidents. Responses are scored using the Bennett model of cultural competence. The authors discuss ways in which the instrument can be adapted by instructors interested in assessing and improving their own cultural competence.


This paper presents the development and laboratory evaluation of a PM10/2.5/1.0 trichotomous sampling inlet that consists of two main parts: a previously designed PM10 size‐selective inlet part and a PM2.5/1.0 two‐stage virtual impactor, which was newly fabricated and attached serially to the PM10 size selective inlet part. Particles are collected in three locations through the trichotomous sampling inlet to provide for not only particle concentration measurements of PM10, PM2.5 and PM1.0, but also those of PM2.5–10 and PM1.0–2.5.


The Search for the Perfect Color: Pigments, Tints, and Binders in the Scientific Expeditions to the Americas Interest in the natural world of the Americas began at the very moment when Europeans set foot on the continent. The natural abundance unfolding before their eyes held the promise of inexhaustible sources of capital, all of which would need to be documented. Francisco Hernández, Bernardino de Sahagún, José de Acosta, León Pinelo, and Bernabé Cobo are only a few of the names among an extensive number of chroniclers, explorers, and naturalists who dedicated themselves to investigate, categorize, and characterize the vegetable, animal, and mineral species of the New World between 1500 and 1700. Their written reports and artistically rendered illustrations of natural phenomena greatly broadened Spain's appreciation of the potential wealth of the American colonies and motivated the Crown and its servants to invest more of its resources in the New World. Thanks in no small part to the Enlightenment, which viewed scientific progress as a tool for the improvement of society, agriculture, industry, and commerce, scientific interest in the natural world reached a notable momentum in the eighteenth century. This spirit of progress and the desire to optimize the use of natural resources led Europeans to promote scientific explorations in all of their overseas possessions, dramatically boosting botanical, zoological, geological, ethnological, and archaeological empirical studies.


Currently housing industry is confronted with enormous risks as a result of the full maket openning and pluralistic investment.In this case project management requives correct risk assessment,for which the methods need be both practically and theoretically applicable.This paper introduces AHP-based method to this task.


For the complete graph K n , its rupture degree is defined as 1−n; and for a noncomplete connected graph G, its rupture degree is defined by r(G)=max{ω(G − X)−|X|−m(G − X):X ⊂ V(G), ω(G − X) > 1 }, where ω(G − X) is the number of components of G − X and m(G − X) is the order of a largest component of G − X. It is shown that this parameter can be well used to measure the vulnerability of networks. Li and Li proved in 2004 that computing the rupture degree for a general graph is NP-complete. In this paper, we give a recursive algorithm for computing the rupture degree of trees, and determine the maximum and minimum rupture degree of trees with given order and maximum degree.


The computer-aided design method is useful in designing all kinds of link mechanisms including industrial robots and manipulators. The authors also have developed another general-purpose simulation system for link mechanisms. Topological and kinematic analyses have already been referred to in the preceding paper. In this paper, a method for the analysis of transient response in dynamics is presented. In this system, both the characteristics of the control system, which are defined as transfer functions among such nodes as the feedback value, desired value and controlled value, etc., and those of the mechanical system, which are represented as equations of motion, are automatically and simultaneously transformed into state equations. Transient responses, for example, responses for displacement, velocity, acceleration and the driving force of joints are calculated by a numerical integration of these state equations. In addition. this system, affords an animated representation to help understand the results of simulation visually.


According to the first principles,the lattice structure,elasticity and electronic properties of three kinds of chromites spinel subject to slight structural variation are studied by the pseudowaves plane(PWP) approach based on density functional theory(DFT) and generalized gradient approximation(GGA).The calculated and experimental results are compared and show that the values of lattice constant,bulk module and shear module are all in good agreement.The slight structural variation enables the bulk modulus to decrease considerably and the Young's modulus increases clearly with increasing coordinate value of atomic oxygen,but the shear modulus and Poisson ratio decreases substantially.It is concluded that the electron exchange action between iron and chromium actions is the main influencing factor on the variation of the elasticity after analyzing the electronic properties such as DOS(density of states),the most nearest-neighboring bond lengths between Fe/Cr actions and O anion and electronic populations.


That's the million-dollar question. When it comes to marketing, you want to know what your customers need. When it comes to AAPM, we want to know what you, our members, need and would benefit from the most. We asked that question at our recent member forum. We asked you what was the most important thing the Academy does for you.

The response was clear—the Annual Meeting and networking opportunities came in at 38% each. The journal and publications followed with a 12% response. Your Academy leadership is responding directly to your needs. The Annual Meeting and its networking opportunities and our journal are at the top of our priority list.

Have you been to our Annual Meeting lately? Our next one is in Palm Springs, California—February 23–27, 2005—it is the perfect venue. Please mark your calendar now. You will not want to miss this meeting. It is unsurpassed for quality in education. We bring together the best and brightest for this event. You also have the …


The connector assembly (100) for coupling a first and a second bus bar (74, 76) on a bus bar assembly having first and second contacts (58, 62) at a power module (55), said first bus bar (74) has a first terminal and the second bus bar (76) has a second terminal, and wherein the first terminal is arranged in the vicinity of the first contact and the second terminal is located in the vicinity of the second contact, the assembly comprising: a first bridge (112) having a first end (115) and a second end (117), wherein the first bridge (112) comprises: overlapping a first connecting strip (106) which is arranged with the first port near the first end (115) of the first bridge (112), and with the first and second bus bar (74, 76); a first end terminal (122), which is arranged with the second contact in the vicinity of the second end (117) of the first bridge (112); and is coupled to a first central area (114) between the first connecting strip (106) and the first end terminal (122); and a second bridge (116) having a first end (119) and a second end (121), wherein the second bridge (116) comprises: overlaps a second connecting strip (110) which is coupled to the second port near the second end (121) of the second bridge (116), and with the first and second bus bar (74, 76); a second end terminal (126) coupled with the first contact in the vicinity of the first end (119) of the second bridge (116); and a second middle region (118) between the second connecting strip (110) and the second end terminal (126) is coupled, and wherein the first and second mid-range (114, 118) are arranged to overlap substantially, wherein a through the first bridge (112) formed by a current path and the second bridge (116) formed current path intersect.


Sorting is one of the most investigated tasks computers are used for. Up to now, not much research has been put into increasing the flexibility and performance of sorting applications by applying emph{reconfigurable} computer systems. There are parallel sorting algorithms (emph{sorting circuits}) which are highly suitable for VLSI hardware realization and which outperform sequential sorting methods applied on traditional software processors by far. But usually they require a large area that increases %But usually they also have a high area requirement, increasing with the number of keys to be sorted. This drawback concerns ASIC and statically reconfigurable systems. In this paper, we present a way to adopt the well-known Bitonic sorting method to dynamically reconfigurable systems such that this drawback is overcome. We present a detailed description of the design and actual implementation, and we present experimental results of our approach to show its benefits in performance and the trade-offs of our approach.


In this paper,we proved that every representation of compact group is a direct sum of irreducible representations.Also,according to properties of the mean operator,we get some results about irreducible representations of compact groups.


Abstract The paper addresses the question of how different types of regions mill be affected by the development of a major new transport infrastructure such as the Channel Tunnel. It summarizes a study on the regional impacts of the Channel Tunnel throughout the European Union (EU). The research design combined qualitative methods of futures exploration employing 13 regional case studies with quantitative forecasting techniques using the MEPLAN transport and economic model. The paper presents the methodology and major results of the two approaches with respect to the impacts of the Channel Tunnel on transport flows and regional development in Europe and draws conclusions for transport and regional policy of the EU. The paper demonstrates that the removal of a bottleneck like the Channel Tunnel does not necessarily induce economic gains in all adjacent regions. Much more important for regional economic development than the reduction of transport costs are the image to be a region well integrated into the E...


The Facility for Antiproton and Ion Research (FAIR) and the Nucleon-based Ion Collider fAcility (NICA) will use fast ramped superconducting magnets with a curvature of 55 m and 15 m respectively. Compared to normal conducting machines with equivalent field strength, the field quality of superconducting magnets is very sensitive to the real geometric details due to its much smaller yoke size. Further the closed cryostat makes it tedious to add correction elements at a later stage. Therefore the measurements must provide a reliable full information of the magnetic field strength, the field direction as well as the field homogeneity and its harmonics. We outline the theory developed, show principal useable coordinate systems, present their features, and outline how the measurement can be made in practice next to first test results obtained on measuring the curved full size model dipole for the heavy ion synchrotron SIS100.


Fixed-point attack on the key parts of small aerial vehicles is one of the important means of UAV (Unmanned Aerial Vehicle) countermeasure. Fixed-wing aircraft flying in the air has two characteristics: fast speed and fast attitude change of aircraft. However, the traditional detection method of key parts of fixed-wing aircraft in infrared images is not only slow in speed but also low in accuracy. This paper presents an improved target detection and motion tracking algorithm based on deep learning method. The algorithm uses a deeper neural network to enhance the feature extraction capabilities of CNN and obtain richer feature information. The detection algorithm obtains the position and motion direction of the key points of the target. Experimental results show that the detection algorithm proposed in this paper is up to 30 frame/s, with an average accuracy of 91.5%/. The method achieved good results in the experiment.


The relationship between seawater nutrient concentrations and ecosystem production was studied by in situ growth experiments, which have been conducted along the nutrient concentration gradient from the eutrophic Osaka Bay head to the oligotrophic adjoining Harima Sea. Bivalves (asari clam Ruditapes philippinarum) were cultured in suspended cargo, and sessile organisms were collected on a suspended plate at each station. The distribution of the primary production was also calculated within the study area. The wet weight of the molluscous part and the condition index of asari clam are strongly correlated with the annual mean total nitrogen (TN). The primary production (PP) is significantly correlated with TN in the area of TN > 0.2 mg L. In contrast, PP is small and of a pelagic nature in the area of TN ≦ 0.2 mg L. The annual mean TN is strongly correlated with TP, and TN = 0.2 mg L is equivalent to TP = 0.029 mg L.


The Exercise Pressor Reflex (EPR) is activated during exercise to increase cardiovascular function. Acetylcholine (ACh) triggers muscle contraction and could be a potent signal of muscle activity during exercise. We show that nicotinic ACh receptors (nAChR) are expressed by muscle afferents.


This book constitutes the refereed proceedings of the 13th IFIP WG 6.1 International Conference on Distributed Applications and Interoperable Systems, DAIS 2013, held in Florence, Italy, in June 2013, as part of the 8th International Federated Conference on Distributed Computing Techniques, DisCoTec 2013. The 12 revised full papers and 9 short papers presented were carefully reviewed and selected from 42 submissions. The papers present state-of-the-art research results and case studies in the area of distributed applications and interoperable systems focussing on cloud computing, replicated storage, and peer-to-peer computing.


The article illustrates the system of construction project organizational management,discusses the contents of construction project quality management from establishing quality assurance system,strengthening the control of personnel,materials,machineries,methods and environment,introduces the principle of cost management and safety production management,and points out that the management of construction project should be comprehensive and man should strengthen organizational coordination in order to increase whole project management level and promote the development of enterprise.


Photorefractive two-wave mixing based on either diffraction or photoelectromotive force has been tested for a low superluminescent light emitting diode. We demonstrate potential applications of two-wave mixing in photorefractive quantum wells for coherence domain detections.


CRISPR tool has the ability to manipulate the nucleotides at precisely desired location. Therefore, CRISPR is becoming an important tool in medical research as well as in agriculture. Various groundbreaking developments have been done in medical research employing CRISPR tool for studying diseases such as cancer, tumour and inherited genetic diseases including hereditary retinal degeneration, HIV infection, inborn genetic disorders, and recessive genetic diseases [1-5]. To study any disease, availability of disease models is the crucial stage for understanding the disease and its associated pathology. CRISPR mediated approach is the easiest, versatile and mostly employed method in medical research for developing such disease models. Here, we present a meta-analysis to identify the mostly studied diseases in medical research using CRISPR tool from the available reports on PubMed.


Global changes have posed a profound impact on the earth's life system. The mechanism with which plant responds to global changes would help us to take measures on the practice of adjustment and optimization of ecosystem. Gansu, located along the northeast margin of Qinghai-Tibet Plateau, northwest of China, is quite divers in vegetation, physiognomic types and climate features. From the south to the north, there occurred subtropic evergreen broad-leaved forests, warm temperate broad-leaved forests, frigid-temperate coniferous forests as well as desert shrublands with a span of 10 latitudes and 15 longitudes(93°25'~108° 42'E,32°18'~42°18'N).This paper, based on previous study on floristic inventories and partition of Gansu woody plant flora, focused on the study of correlation between the pattern of plant life form as well as fruit types and hydrothermic factors. 6 Floristic subregions( i.e., that of Zoulang, Zhongbu, Qilianshan, Tianshui, Longnan and Gannan )in Gansu were set for the statistic of life form and fruit types. Totally 1291 woody species belonging to 292genera, 94families were classified into 7 life-form spectra types, that is, lianas, big tree, tree, big shrub, shrub, small shrub as well as parasites and lianas. Some conclusions are as follows: (1) the factors of water and heat were correlated positively with plant life-form of arbor , lianas and parasites and negatively with that in small shrubs. Shrubs with the height of 1.5m ~3m were negatively correlated with annual mean precipitation and annual mean temperature and(2)hydrothermic factors were positively correlated with evergreen plant and negatively with deciduous plant.(3)The percentage of evergreen in Zoulang was fairly higher than that of Zhongbu where hydrothermic factors were relatively more available in contrast to Zoulang, which mainly resulted from the specific background of floristic origin in Zoulang.(4)Humidity was correlated positively with sarcocarp while negatively with dry fruit ,which suggesting that moisture conditions might shape the allocation patterns of dry fruit and sarcocarp in a given communities. (5) Cone was correlated negatively with heat factors while positively with moisture. Key fruit, nut, drupe, follicle, caryopsis were positively correlated with hydrothermic factors. Berry was significantly posotively correlated with humidity degree. Capsule was negatively correlated with hydrothermic factors, which indicated that capsule might derived under cool and dry climate. Utricle was negatively correlated with annual mean precipitation. (6) Species diversity, life form and fruit type, height of tree were correlatively changed along a environmental gradient. To clarify the evolutionary sequence among plant fruits would be helpful to both disclose the pattern of fruits and further the study on the mechanism with which plant responds to environmental changes.


We propose an optimization and generalization of OT extension of Ishai et al. of Crypto 2003. For computational security parameter k, our OT extension for short secrets o↵ers O(log k) factor performance improvement in communication and computation, compared to prior work. In concrete terms, for today's security parameters, this means approx. factor 2-3 improvement. This results in corresponding improvements in applications relying on such OT. In particular, for two-party semi-honest SFE, this results in O(log k) factor improvement in communication over state of the art Yao Garbled Circuit, and has the same asymptotic complexity as the recent multi-round construction of Kolesnikov and Kumaresan of SCN 2012. For multi-party semihonest SFE, where their construction is inapplicable, our construction implies O(log k) factor communication and computation improvement over best previous constructions. As with our OT extension, for today's security parameters, this means approximately factor 2 improvement in semi-honest multi-party SFE. Our building block of independent interest is a novel IKNP-based framework for 1-out-of-n OT extension, which o↵ers O(log n) factor performance improvement over previous work (for n  k), and concrete factor improvement of up to 9 for today's security parameters (n=k=128). Our protocol is the first practical OT with communication/computation cost sublinear in the security parameter (prior sublinear constructions Ishai et al. [IKOS08, IKOS09] are not e cient in concrete terms).


A planar metallic pattern, such as one of a circuit board, is imaged contactless by two-dimensionally scanning the pattern plane with a probe-to-probe transmission measurement system. The distance between the probe tips is about a quarter wavelength, allowing for the use of higher-order mode evanescent fields for the transmission. Coupling of linearly polarized field modes to the circularly-symmetrical higher-order TM01 mode is dependent on the orientation of the metallic edge at a specific spot of the imaged pattern, allowing for the detection of edge orientation by a single-pixel measurement. The concept is experimentally demonstrated at 31 GHz with subwavelength resolution of metallic features.


In this article we intend to show some precedents of the discussion on the meaning of the Enlightenment (1783-1784) from some linguistic controverses around the phenomena entusiasta. So comes the need to distinguish between "Enhusiasmus" and "Schwarmerei" - talked by authors like Wieland, Herder, and Lessing – that had already been antecipated by the dilemmas inherent to auto-understanding of the project Enlightenment. During the eighties,  pluralizations of meanings of the term "Schwarmerei" lead to that crisis grown around the senses of the term "Aufklarung". We had disputing concepts as rationality and autonomia subjective.


The purpose of this paper is to assess the eco-environmental sensitivity and the spatial distribution through a assessment system including four types of factors,such as soil erosion,water condition,atmosphere condition and biodiversity.Methods employed were Fuzzy Matter-element Model,the advanced GIS technology,and factor-overlay method.The results indicate that five levels of ecological sensitivity ranging from the highest to the lowest were classified,including extreme zone,high zone,moderate zone,slight zone and insensitivity zone,and meanwhile a synthetic distribution map of environmental sensitivity was obtained..The conclusion is that the findings in the paper provide the scientific basis for the ecological distribution,which was useful for the layout of diverse land types in Yicheng City.Furthermore,the FMM and GIS methods are applicable for the eco-environmental sensitivity assessment.


BAckGround: In a hospital setting, paediatric eye disease manifests itself in a complex network. It is essential to comprehend the scope of many common eye disorders in order to develop new evidence-based strategies for miti-gating such disorders. The study aimed to investigate the hospital-based prevalence of pediatric ocular disorders of patients attending a tertiary eye care hospital. MAterIAl And MethodS: A three-year data from 2017-19 were extracted from the electronic medical records of Chandraprabha Eye Hospital, Assam, India. Refining the data was further carried out using the age criteria up to 18 years. The diagnosis for all the study subjects was taken into consideration and was further analyzed. The inclusion criteria included subjects within the range of 0-18 years reporting to the hospital during the study period. Subjects diagnosed with non-ocular problems, incomplete ophthalmological assessments, and those aged more than 18 years were excluded. reSultS: A total of 11807 relevant medical records were reviewed. Among the study subjects, 58.52% (n = 6910) were males. The mean (SD) age was 11.9 (4.8) years. Of the subjects 21.28% (n = 2513) were in age group 0–5 years, 42.39% (n = 5006) — in 6–11 years, and 36.31% (n = 4288) in 12–18 years. A total number of 152 pediatric ocular abnormalities were identified from the reviewed files. Myopia alone accounted for 19% of all, followed by vernal keratoconjunctivitis with 14.7%, followed by asthenopic presentation associated with non-strabismic binocular vision anomalies (7.4%), congenital nasolacrimal duct obstruction (2.9%), amblyopia (2.8%), and ocular injuries (2.7%). concluSIonS: Refractive errors, allergic conjunctivitis, ocular injuries, amblyopia and squint, uveitis, congenital cataract, and non-strabismic binocular vision anomalies were identified as the most common pediatric ocular abnormalities seen in routine clinical practice, laying the groundwork for a standard protocol to evaluate and assess visual function in any case of pediatric anomaly.


In the judicial practice,the right of suit for public welfare already arouse more and more interests,procurator agency's public welfare suit right was not only a kind of lawsuit right,it but also manifest a kind of principle of government by law and the constitutional government spirit,which manifest value of procurator agency's examination power in the public welfare lawsuit,reflect its legal concern to the social public interest,it require the procurator agency to deal correctly with litigant autonomous thought when exercise the public welfare suit right,fully realize function of public welfare suit right in judicial activity.


To study the corrosion behavior of second phase particles in zirconium alloys, Zr(Fex, Cr1−x)2 (x=1, 2/3, 1/3) metallic compounds which have the same composition as the second phase particles in Zr-4 alloy were prepared by vacuum non-consumable arc melting. XRD and energy filtered TEM were employed for analyzing the corrosion products, the element distribution and grain morphology after corrosion tests of Zr(Fex ,C r1−x)2 metallic compounds powder at 400 and 10.3 MPa superheated steam with different exposure times. The results show that Cr has a very strong effect on the corrosion resistance of Zr(Fex ,C r1−x)2 metallic compounds, increasing Cr content can improve the corrosion resistance. When Zr(Fex ,C r1−x)2 oxidation starts, zirconium oxide is formed while elements Fe and Cr are expelled from the zirconium oxide due to their low solid solubility in the oxide. α-Fe(Cr) and γ-Fe(Cr) are formed and then oxidized to the stable corrosion product (Fe, Cr)3O4. The different corrosion behaviors of metallic compounds will affect the microstructure evolution of zirconium oxide layer differently during the corrosion process, and hence affect the corrosion resistance of zirconium alloys.


In this paper a branching process approximation for the spread of a Reed-Frost epidemic on a network with tunable clustering is derived. The approximation gives rise to expressions for the epidemic threshold and the probability of a large outbreak in the epidemic. We investigate how these quantities vary with the clustering in the graph and find that, as the clustering increases, the epidemic threshold decreases. The network is modeled by a random intersection graph, in which individuals are independently members of a number of groups and two individuals are linked to each other if and only if there is at least one group that they are both members of.


Four numerical simulations of the NASA Active Noise Control Fan rig with some modifications have been performed to investigate the influence of the heterogeneity of the stator row on the tonal nois...


ABSTRACT What accounts for the variation in EU actorness in cases of contested statehood in the European Neighbourhood? A comparative analysis of the EU's policies vis-à-vis three territorial conflicts – Kosovo, Abkhazia and Western Sahara – demonstrates the intricate relationship between external conditions and internal EU capability leading to substantial involvement, partial involvement or non-involvement in conflict management. Using insights from the EU actorness debate and the literatures on contested statehood and EU external governance, the paper offers a conceptualisation of the EU's conflict management role and a contingent explanation of the EU's varying commitment to managing conflicts in three cases of contested statehood. The paper finds that external determinants have a considerable weight in EU's policies which existing research tends to overlook owing to its predominant focus on EU's internal institutional procedures and instruments. It teases out the external action-enabling and action-hindering factors, in particular the external structural constraints arising from the nature of statehood contestation and the agency of other international and local players in the three conflicts in the European Neighbourhood.


New data sets from the ArcticDEM project help scientists track elevation changes from natural hazards like volcanoes and landslides before, during, and long after the events.


The purpose of this paper is to report on the state-of-the-practice in sustainable pavement maintenance and preservation. This paper is concerned and directed at understanding how pavement maintenance and preservation practices minimize environmental impacts. The Federal Highway Administration (FHWA) differentiates between pavement preservation and pavement maintenance and uses this to allocate federal funds accordingly. While Canadian agencies recognize and practice the concepts of pavement preservation, there is no regulatory differentiation between it and maintenance as compared to the United States (U.S). Pavement preservation promotes environmental sustainability by conserving energy, virgin materials, and reducing greenhouse gases by keeping good roads good. Therefore, the foundation of a sustainable pavement maintenance program is to commit personnel and resources to pavement preservation. Currently, public agencies in the U.S. and Canada have done very little to extend the knowledge gained from research and practice in sustainable highway project delivery beyond construction completion and into the pavement preservation and maintenance phase of the road's life cycle. Thus, there are many opportunities for future research and enormous potential for agencies to accrue benefits in this area of practice. Treatments identified in this paper are primarily related to preservation and maintenance. However, these are not exclusive to preservation and maintenance and can be used in pavement rehabilitation.


The present invention relates to compounds of formula (I) wherein R 1 represents an atom of sulfur or selenium, R 2 represents hydrogen or alkyl, R 3 - R HIS B, 4 - R 5 represents a chain of formula : E CH -CH 2 CH 2 -, -CH (R 7) - CH 2 - CH 2 -, CH 2 CH 2 -CH (R 8) -, -CH 2 - CHR 9) CH 2 -, CH 2 - CH 2 - S-, -CH 2 - CH 2 - SO-, -CH 2 - CH 2 - SO 2 -, -CH 2 - CH SUB, 2 - SE-, CH 2 CH 2 - O-, -CH 2 - CH 2 CO-, -CH 2 - CH 2 - N (R 10) -, -CH 2 - CF SUB, 2 - CH 2 -, -CH 2 CH 2 -CH (OH) -, -CH 2 - CH (R 13) - S-, -CH 2 CH (R 13) - SO- or -CH SUB, 2 - CH (R 13) - SO 2 -, R 6 represents a polyfluoroalkyl RADIC AL, polyfluoroalkoxy O POLIFLUOROALQUILTIO, R 7 represents alkyl, CH2OH, CH 2 - SO 2 - alkyl or -CH 2 - NR 11 R 12, R 8 represents alkyl, hydroxy, -CH2OH, NR 11 R 12, CH 2 - NR 11 R 12, -S - ALK, -SO - ALK, -SO 2 - alkyl, thienyl, furyl, phenyl or phenyl USTITUIDO, R 9 represents alkyl or -CH2OH, R 10 represents HID ROGENO or alkyl, R 11 is HIDROGENJO O Alkyl, -CO - alkyl or CO - CF 3, R 12 represents hydrogen or alkyl, or R 13 YR 12 form with the nitrogen atom to which they are NITROGERNO a heterocycle; R 13 represents alkyl or -CH2OH, their salts, their preparation processes, CONTAINING DRUGS AND INTERMEDIATE.


The crystal structures of salts of the active pharmaceutical ingredient (API) called salinazid with dicarboxylic acids and acesulfame were determined by single-crystal X-ray diffraction method. The crystals contain hydrogen bond motifs of different structure and complexity, the energies of which were estimated by using the quantum theory of atoms in molecules and crystals (QTAIMC) methodology. It was found that the driving force for facile the oxalate and malate salts formation is the bifurcated N+–H···O– and N+–H···O hydrogen bond synthon, while salinazid malonate is mainly stabilized via a "classic" pyridinium-carboxylate heterosynthon. The oxalate and acesulfame salts of salinazid were found to be stable during aqueous dissolution experiments, providing a substantial solubility improvement compared to pure API (33 and 18 times, respectively). However, the malonate and malate salts dissolved incongruently and rapidly underwent a solution-mediated transformation to form pure salinazid. Based on the solub...


of a dissertation at the University of Miami. Dissertation supervised by Associate Professor Amie L. Nielsen. No. of pages in text. (216) A large number of studies show that immigrant residential concentration is associated with lower crime rates. These findings challenge public opinion which consistently links immigration with higher crime rates and the predictions made by some social scientists regarding the life chances of immigrants in America. The negative association between immigration and crime is often referred to as the immigrant paradox. Recently, immigrant enclave theory has emerged as the key explanation of the immigrant paradox. This theory was originally developed by sociology of immigration scholars. In this dissertation I argue that criminologists have failed to properly integrate immigrant enclave theory into immigration and crime research. My review of the sociology of immigration literature shows that immigrant enclaves emerge in geographical areas with a large number of ethnic businesses and large coethnic immigrant populations. I also argue that, in addition to enclaves, criminologists should consider alternative forms of immigrant community organization such as immigrant employment niches, middleman minority communities, and immigrant ghettos. I draw on social capital and related theories to show that these different forms of immigrant community organization should vary in their capacity to control crime. I test key assumptions of my theoretical framework using homicide victimization data from the National Vital Statistics System (2002-2004), homicide and robbery incident data from the Uniform Crime Reports (2002-2004), ethnic business ownership statistics from the Survey of Business Owners (2002), and social and demographic information from the 2000 decennial Census of Population and Housing. I focus on Latino immigration because of its current importance in immigration and crime research and because of the availability of reliable data. The results of my dissertation generally support my theoretical framework. Specifically, I found that violent crime rates vary between different forms of immigrant community organization after controlling for important structural predictors of crime. Furthermore, consistent with the theory, immigrant enclaves have the lowest violent crime rates while immigrant ghettos have the highest rates compared to other types of immigrant communities. In light of these findings, I recommend that future criminological research consider differences between immigrant communities. I also recommend that policy makers recognize the benefits immigration has for crime prevention. I argue that these benefits can be further enhanced by helping immigrants become business owners or gain and maintain employment as salaried workers. The current anti-immigrants policies should be revised and possibly discarded.


This study evaluates the shear performance of precast reinforce concrete beams with ground granulated blast furnace slag (GGBS) cements. The specimens with various replacement ratios of GGBS (0%, 30% and 50%) were cast and tested in shear. As a result, it was found that the specimens with 30% and 50% GGBS showed a similar shear strength compared to the specimen with portland cements alone.


The psychopractic approach requires that extreme scoring on measures of pro attitude, and similar variables, be treated with care, and testing of such variables is underway in a replication study of the I Ching experiment. These variables measure motivational and/or emotional investment, and therefore they can indicate participants who are highly charged.


in calling for an argument that emphasizes the harmony between personal rights and military needs. At the very least, such an approach would provide a rhetorical stance more acceptable to those who must be convinced. I hope this approach will also lead to a substantive reconciliation of the rights of the citizen-soldier and the demands of military discipline. For further reflections along these lines, one might supplement the arguments of Conscience and Command with Morris Janowitz' characterization of the military authority from "domination" to "manipulation."


Background: Hypertension (HTN) is a non-communicable disease that contributes to heart disease, stroke, kidney failure, and premature mortality and disability. The majority of cardiovascular disease deaths, approximately 80%, occur in low and middle-income countries such as India. Therefore, it is crucial to explore the Ayurvedic perspective on HTN to enable Ayurvedic healthcare providers to effectively manage HTN and its complications. Objective: The aim of this article is to review the Ayurvedic concept of water balance, blood, and blood pressure, and investigate their potential involvement in the development of HTN. Materials and Methods: We conducted a critical review of scattered references in Ayurvedic literature pertaining to water balance and the role of Doshas in maintaining it. Results: Water constitutes a major component of blood, and alterations in plasma volume can impact blood pressure levels. The literature review highlighted the similarity between the properties of Kapha and Pitta and the water-dominant attributes, suggesting their potential to disrupt water balance. Conclusion: Ayurveda emphasizes the greater involvement of Kapha and Pitta in maintaining water balance in the body, while Vata is responsible for its circulation. Factors leading to the imbalance of Kapha and Pitta may initiate and contribute to the pathogenesis of hypertension, which necessitates thorough consideration for effective Ayurvedic management.


a pulse tube cooler based on diaphragm will be introduced in this paper.An acoustic transparent but oil blocking diaphragm is used as the interface between an oil lubricated compressor and a pulse tube cooler,so that the compressor can be use as the driver of the cooler.Another diaphragm is installed in the loop of the cooler where DC flow parasitizes to suppress the DC flow. With 2.1 MPa charging pressure and 25 Hz working frequency,this pulse tube cooler can obtain a cooling temperature of 29.8 K.


An almost abrupt change in attitude towards applications in the field of renewable energies has emerged in recent months, both among decision-makers in politics and in companies. [1]
In particular, the topic of hydrogen production by electrolysis plays an eminently important role. In water electrolysis, water is split into its constituent ¬parts hydrogen and oxygen using electrical energy. The resulting hydrogen is of interest to future energy systems for a number of reasons, including the fact that hydrogen can serve as a storage medium for electrical energy from renewable energy conversion systems such as photovoltaic or wind turbines.


Purpose
Shari'ah provides the basic tenets of the Islamic finance industry and advocates banks to share their profits and losses with investors. But what it means for a firm to be "Shari'ah-compliant" and what form of connections it can have, even in theory, to either the firm's value or profitability is still an untapped question. This study tries to answer this question. This study aims to find the impact of Shari'ah compliance on firm performance. The results obtained would be useful in helping investors, regulators, companies, government, academicians and practitioners in their decision-making process as to ensure better economic and business gains, both locally and globally.

Design/methodology/approach
Panel data on 634 Shari'ah-compliant firms have been used in this study for the period of 2000–2014.

Findings
The results indicate that Shari'ah compliance adds to the value of firms as firms perform transactions according to Shari'ah while avoiding non-permissible activities.

Originality/value
This study adds value to the existing literature by showing the statistical results for the impact of Shari'ah compliance on the performance of the listed firms on Bursa Malaysia.