AbstractThe treatment described was primarily a problem in textile conservation, although the fan is composed of silk, metal, and ivory. The major difficulty encountered was the extreme fragility of the embroidered silk panel. Reversible materials were used as far as possible, although in practice these would be difficult to remove without destruction of much of the silk. The methods used are not all new but their application here is of interest because of the complexity of the problem and the urgent need for consolidation of objects made with similar materials. The fan was strengthened and restored to a point where it can now be handled, studied, and exhibited under proper conditions.


Although the speed of eGFR decline is usually rapid in patients with diabetic nephropathy (DMN) and a nodular lesion (NL), some patients with NL experience a slow eGFR decline. The factors associated with the difference in prognosis remain unknown. In this study, we aimed to explore prognostic factors by performing transcriptome analysis on preserved residual renal biopsy specimens from patients with pathologically diagnosed and prognostically known DMN with nodules.

 Patients who had an annual eGFR drop rate > 5 mL/min/1.73 m2 were defined as rapid decliners (RD) and the others as slow decliners (SD). Twelve patients (RD = 6 and SD = 6) who underwent kidney biopsy, had no other renal comorbidities, and had been followed up for at least one year were included. Total RNA was isolated from renal biopsy tissues in formalin-fixed, paraffin-embedded blocks, and microarray analysis was done.

 At the time of renal biopsy, the eGFR, urine protein, and rate of sclerotic glomeruli were not statistically different between the RD and SD groups, at 49.7±10.1 mL/min/1.73 m2 and 57.5±12.4 mL/min/1.73 m2 (p = 0.258), 7.5±4.2 g/gCre and 4.0±2.7 g/gCre (p = 0.123), and 19.2±13.4% and 25.5±14.4% (p = 0.450), respectively. In microarray analyses (total 58,341 gene probes), genes with little expression (raw signals <50) and with little differences between RD and SD (processed signals <0.3) were excluded, leaving 14,227 genes for further analysis. A total of 1,496 differentially expressed genes (DEGs) were selected with p-values <0.05 and fold change ≥2 between the RD and SD group for further bioinformatic analysis. Using the Ingenuity Pathway Analysis system, 15 canonical pathways and 9 diseases or functions annotations were found to be enriched. In addition, upstream regulator analysis identified 73 upstream regulators. Among them, only two regulators, CBX5 and CCN5, showed p <0.05 and absolute z-score > = 2 as activated and inhibited regulators, respectively, in the RD group. We next performed regulator effects analysis, indicating one regulator network which identified the key upstream regulator CCN5. The regulator network also showed a small number of genes involved in the viral infection, which included CDH1, CD24, and ESR1. Additionally, IPA showed 25 interaction networks ranging from 11 to 38. The fifth-ranked network was associated with Cancer, Organismal Injury, and Abnormalities (score = 32), in which CD24 and ESR1 were included. We, therefore, performed qRT-PCR to compare the expression levels of CDH1, CD24, and ESR1 in the RD group with those in the SD group. The expression levels of CD24 and ESR1 in the RD group were downregulated compared with those in the SD group (p = 0.004 and p = 0.022, respectively) although there was little difference in the level of CDH1 between them (p = 0.638).

 Transcriptomic analysis using renal biopsied tissue revealed that ESR1 and CD24 might be candidates for renoprotective factors in DMN with NL.


Advertisement call structures of ten frog species, six ranids and four rhacophorids, from southwestern India were analyzed. Rana temporalis, Limnonectes limnocharis, Indirana semipalmata, Nyctibatrachus major, and Philautus cf. bombayensis had simple calls consisting either of a single note or of a series of similar notes. Limnonectes cf. keralensis and P. cf. travancoricus had a relatively long call with a well-differentiated first note, and L. syhadrensis, P. leucorhinus, and Rhacophorus malabaricus had complex call structures with a variety of call types. Several ecological notes associated with breeding, and some taxonomic problems are presented.


We reported a study of the structural and magnetic properties of BaZrO3 (BZO) as possible substrate material for the production of YBa2Cu3O7-δ (YBCO) superconducting films. Rietveld analyses of the X-ray diffraction pattern show that BZO crystalizes as a cubic perovskite, space group Pm3m (#221). Chemical stability and crystallographic coupling between BZO and YBCO were examined by characterizing YBCO/BZO (10, 30 and 50 YBCO vol%) polycrystalline composites. Morphological and compositional analyses of composites were performed through scanning electron microscopy and energy dispersive X-ray experiments, respectively. Response of magnetization measurements revealed that the proximity of BZO does not affect the superconducting transition temperature (Tc=90,2 K) of YBCO material. Our results evidenced that the BZO is an excellent candidate to be substrate for the fabrication of YBCO superconducting thin films.


For a vehicle suspension component or assembly, including: a wheel carrier is supported between the hub carrier, the carrier, and the carrier is between the hub carrier and one or more support bodies. Relative to the bottom by the bottom of the suspension or the suspension of the support body. The one or more first support body having a predetermined stiffness in a first direction, and having a second stiffness in a direction perpendicular to the first direction, wherein the first direction and oriented such that the longitudinal direction of the vehicle with the vertical straight plane intersecting, and wherein the second stiffness less than the first stiffness.


Introduces the fine chemical engingeering specialty construction in Higher Vocational Colleges,separately from the" occupation " of professional construction concept,fine chemical professional curriculum system construction,pay attention to practice teaching mode,higher vocational fine chemical engingeering and environmental protection professionals with training,and actively promote the fine chemical professional bilingual teaching system construction in five aspects.Put forward the fine chemical engingeering specialty construction scheme,and the specialty construction and prospect.


The changes of chemical components and tribological properties of TiN MoS x /Ti composite coatings caused by largely ion etching S from its surface are studied by XPS. After long time ion etching, the surface Mo/S ratio of the composite coatings decreases from 2 03 to 1 25 with a concomitant reduction in the Mo 3d 5/2 binding energy from 231 73 eV to 231 07 eV. After 5 minutes ion etching, the surface of coatings presents a deep black colored compact structure with excellent tribological properties; but after 15 minutes ion etching, the surface of the coating presents a french grey colored loose structure with greatly decreased tribological properties.


This is a brief report of the final Plenary Session of the anniversary meeting of the Acoustical Society of America in Cambridge, Massachusetts in June 1979. It summarizes briefly conjectures about the future of acoustics with special reference to interdisciplinary technology, hearing problems, noise, and physical acoustics.


OBJECTIVE To investigate the neuroproteelive effect of acetylpuerarm (compound N-2211)and peurarm on focal cerebral is-chemia-reperfusion injury. METHODS The NO level and NOS activity in brain tissue and serum were measured in the rats with reversible middle cerebral artery occlusion( MCAO) without cramectomy. RESULTS The levels of NO and NOS in brain homogenate increased significantly in ischemia-reperfusion group,compared with sham group, and there was the same change happened for the level of NO in serum.NO and NOS levels decreased in acetylpuerarin-treated groups and peurarin-trealed group, compared with ischemia-reperfusion rats. At the same time, the number of living pyramidal cells in CA1 region of hippoeampus increased significantly in acetylpuerarin-treated rats and peurarin-treated rats, compared with ischemia-reperfusion rats. CONCLUSION The results suggested that the effect of acetylpuerarin and peurarin on decreasing NO production played a role on the amelioration of focal brain ischemia-reperfusion injury.


Background: Cervical cancer (CxC) is a leading cause of mortality and morbidity among women worldwide. Current chemotherapeutic agents for CxC have shown systemic toxicity in CxC patients. Ormeloxifene (ORM) is a non-toxic and non-steroidal drug with well-defined pharmacokinetic and pharmacodynamic properties in humans. Studies have shown its anti-cancer potential in various pre-clinical mouse models. Here, we have synthesized and characterized a novel analogue of ormeloxifene, Bromo-ormeloxifene (Br-ORM), which showed more therapeutic efficacy against CxC in vitro and in vivo model systems. Methodology: The effect of Br-ORM on CxC cells (CaSki and SiHa) growth and proliferation was determined by colony formation and MTS assays. Molecular docking of Br-ORM with β-catenin was done by AutoDock4 software. Effect of Br-ORM on the expression of epithelial-to mesenchymal (EMT) markers (N-cadherin, slug, snail), MMPs (MMP2 and MMP3) and miR-200a was analyzed by Western blot and qPCR analyses respectively. Apoptosis analysis was done by Annexin-V staining kit. Effect of Br-ORM on β-catenin cellular localization in CxC cells was analyzed by immunofluorescence analysis. The anti-tumor efficacy of Br-ORM was investigated in orthotopic xenograft mouse model of CxC. Results: Br-ORM (10-20 µM) effectively inhibited growth and proliferation of CxC cells in a dose and time-dependent manner as compared to ORM. Br-ORM efficiently suppressed metastatic phenotypes of CxC cells as determined by significant (P Conclusion: These results suggest that Br-ORM inhibits the metastatic phenotypes of CxC cells via targeting β-catenin signaling pathway. Br-ORM could be used as a novel therapeutic modality for the treatment of CxC. Citation Format: Mohammed Sikander, Shabnam Malik, Bilal B. Hafeez, Sonam Kumari, Sheema Khan, John Apraku, Hassan Mandil, Andrew E. Massey, Aditya Ganju, Parvez Khan, Fathi T. Halaweish, Subhash C. Chauhan, Meena Jaggi. Bromo-ormeloxifene inhibits epithelial mesenchymal transition via targeting β-catenin signaling pathways in cervical cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4809.


Russian success in usage of the SPT-type electricrocket thrusters for different space missions and SPT100 exploitation at the geosynchronous satellites' are the reasons of the great interest to these type of thrusters among the firms, designing space crafts either in Russia or abroad. Nowadays lots of works analysing the possibilities of the SPT-100 usage for some space platforms are appeared. In this case an optimal integration of the electrical thrusters' on board of the spacecraft is veIy important when a new spacecraft is developed. It is practically impossible to do without thruster jet investigation. It is especially actual for SPT in which calculation of the ion flows direction gives only approximate results. The methodological bases for thruster jet investigation, some results of experimental data analysis are represented in this report. The refinement data about SPT-100 jet parameters are also represented.


Inspections and reviews are one of the most effective ways of detecting errors in software development. The methods are also cost-effective because defects can be spotted early in the development, and thus the cost of repairing the defects is lower. Reading techniques are the procedures that are used in the inspection or review of a software artefact. The most common procedures are simple ad-hoc reading and a checklist-based reading technique. However, more advanced and detailed procedures have been created for various purposes. This report reviews the state-of-the-art software reading techniques used in inspections and reviews, and briefly reviews some of the empirical research in this context. The majority of the empirical research results indicate that, for example, perspective-based reading is more cost-effective and can detect more defects than more basic reading techniques. This report also describes how perspective-based reading can be applied to the inspection of nuclear-domain requirement specifications. For this purpose, seven perspective-based reading scenarios have been created.


Emerging out of 'second wave' feminism, Tania Modleski's writings on women in popular culture shaped feminist challenges to contemporary thinking on the cinema. Bonds unique to female friendships and mother-daughter relationships reset the frame for female spectatorship.


Purpose:  This article aims to examine the scale of social motivation and a measure of the entrepreneurial level of Dayak women working in small (home-based) industries.

Theoretical framework: The context of 'push-pull theory', it emphasizes exploratory factor analysis to test entrepreneurial motivation. Regarding entrepreneurial motivation, there are five vital motives, including cultural preservation, independence, economic support, environment, and work flexibility. They have a massive motivation for entrepreneurship

Design/methodology/approach: We interviewed individual informants, in which a semi-structured schedule explored the responses of Dayak women. Open-ended questions were asked to draw attention to the history of being involved in the business world. Thus, the study adopted a mixed methods approach.

Findings:   The Dayak women have a massive motivation for entrepreneurship. They also realize that the business has been running so far as part of preserving the culture to commit to the family economy. Even though they apply it while taking care of the family, the work environment factor has certainly been tested.

Research, Practical & Social implications: For the future agenda, the concentration of studies refers not only to a specific gender but also to a wider cross section. Extensive comparisons should consider a qualitative approach to explore other problems related to entrepreneurial motivation.

Originality/value: The results indicate that the related entrepreneurship to aspects of risk and income level uncertainty, so the family factor is an essential part.


Objective To observe the healing of rotator cuff injury between the anchor and bone tunnel after repaired with allograft bone anchors in different periods of time.Methods Shoulder bone suture anchors were made using the cortical bone of adult sheep stored at-80℃.Six sheep were used as experimental animals.A median incision was made at the shoulder joint to isolate the supraspinatus tendon which was then sharply cut at its end.The end of supraspinatus tendon attached to the cortical bone was finished with a grater until the fresh bone surface was seen.Cortical bone anchors were slowly implanted into the prepared holes and supraspinatus tendon was sutured onto the fresh bone with sutures in anchors.Specimens were taken at weeks 4,8,and 12,respectively,after operation.Radiology,gross morphology and histology examinations were performed to observe the healing of supraspinatus muscle between the tendon and bone,and the histology turnover of bone anchors.Results The supraspinatus tendon was healed with fresh bones formed 12 weeks after operation.Radiology showed that the cortical bone anchors were fused with bones around them.HE staining of supraspinatus tendon tissue revealed that the cortical bone anchors were completely fused with bones around them 12 weeks after operation.Conclusion Rotator cuff injury between supraspinatus tendon and bone can be repaired with allograft cortical bone anchors,which are then fused with bones around them with no bone defect after operation.


Sir: Biphenotypic sinonasal sarcoma (BPSS) is an exceedingly rare, locally aggressive spindle cell soft tissue neoplasm with high trophism for the sinonasal tract of middle-aged adults, with female predilection. The tumour is characterised immunohistochemically by biphenotypic neural and myogenic differentiation, and molecularly by recurrent gene translocations that involve the PAX3 gene, in more than 90% of cases. Many partner genes have been described, including MAML3 and, to a lesser extent, NCOA1, FOXO1 and WWTR1. Fewer than 10% of BPSS show alternative chimeric products or no detectable genetic alterations. Interestingly, a significant number of cases (80%) show aberrant nuclear immunopositivity for beta-catenin. Although categorised as bearing locally aggressive potential, BPSS generally do not pose high metastatic and mortality risk. One of the most unusual and prognostically relevant features is represented by progression to high-grade morphology years following the initial diagnosis. To date, only a handful of case reports detail this event.


On 24 May 2013 the Finnish Market Court handed down its first decision in a case utilising the recently enacted New Competition Act and the so-called SIEC (significant impediment of effective…


Purpose To evaluate and determine the seroprevalence and epidemiological characteristics of hepatitis E virus in a rural population in Zhejiang Province. Methods Totally 1 850 healthy persons with age over 7 years old were interviewed.Anti-HEV IgG antibody in sera collected from a total of 669 persons was tested with an indirect ELISA. Results Total prevalence of the 663 population was as high as 63.50%,and it was higher in males(70.03%) than in females(57.14%).The prevalence increased with age significantly,but remained a stable level from the age over 30 years old.The association between the prevalence of anti-HEV IgG and history of hepatitis,transfusion,or breeding domestic animals was not statistically significant. Conclusions The data from this study strongly suggested that HEV infection was widespread among the rural population in Zhejiang Province.HEV infection was significantly associated with gender and age.


The Spruce Budworm Technology Transfer Program for the Lake States Region was part of the Canada-United States Spruce Budworms Program. The goal of our technology transfer project was to provide land managers in the Lake States with pest management information on the spruce budworm. We summarize our technology transfer program, give examples of the development of four information packages, and discuss important factors that help technology transfer efforts in forest pest management.


This art~cle reports on the formation of T - Gate with O.1m foot and 0.4m head width at PMMA/P( MMA/MAA) resist structure using a 30KV electron beam lithography system. From the result of Monte Carlo simulation on PMMA/P( MMA/MAA)/GaAs, we obtain the dissipation energy ratio of forwardscattered electron and backscattered electron within 0.1m scattering radius is 19.5 : 1 0.1m T - gate has been formed with 30KV gaussian electron beam at a 440 dosage. The gamma value of PMMA and P(MMA/MAA) at MIBK : IPA=l : 1 developer was 2.3. The overlay accuracy(3) from mix-andmatch of optical stepper and Ekeam lithography system for fabricating HEMT device is accomplished below 0.1m.


The analysis of the reactant products of CuS and HNO_3(analyse daily density)that is in different temperatures and concentrates shows: the reactant products of CuS and HNO_3 not only confine NO、 NO_2 and S,but also have NO_2~-and SO_4~(2-),it is a more complicated reaction.We have analysed and conducted the reaction equation of CuS dissolves in HNO_3 which is in different temperatures and concentrates theoretically.


In recent realist theory and more broadly, pessimism has tended to be treated as a problem or a liability for thought, limiting aspirations for political change and leading towards conservatism. In this article, I turn to Niccolò Machiavelli as a resource through which to theorize differently about the idea. I argue that pessimism in Machiavelli's work can be associated with an effort to look candidly upon political affairs and to express scepticism towards complacency in thought and conduct. Such an approach, rather than tending towards despair or cynicism, can be seen to make different dimensions of history and politics visible and to open up different paths of judgment and decision-making as a result. Rather than constraining thought and action, pessimism in Machiavelli's thinking can therefore reveal novel possibilities for political conduct.


The aims of this study were to measure and compare the mean shear bond strength of different adhesive systems for bonding orthodontic brackets to fluorotic and normal teeth. One hundred and twenty premolar teeth were divided into six groups (N=20), brackets were bond and fixed to the sample teeth. Groups 1, 2 and 3 contained normal teeth bonded with System TM 1+, Unite TM and Super-Bond C&B. Groups 4, 5 and 6 contained fluorotic teeth bonded with System TM 1+, Unite TM and Super-Bond C&B. Thermocycling was performed at 5 + 2 ○ C and 55 + 2 ○ C for 1,000 cycles. Shear bond strength was measured using an universal testing machine at a crosshead speed of 0.5 mm/min. The data were analyzed using two-way ANOVA. The results indicated the mean shear bond strength values of all adhesives used on normal teeth were significantly greater than those used on fluorotic teeth ( p =0.000). With both normal and fluorotic teeth, the mean shear bond strength value of Super-Bond C&B was significantly greater than the mean shear bond strength values of System TM 1+and Unite TM ( p =0.000). Keywords: shear bond strength, adhesive systems, fluorotic teeth


Nuclear power has provided a significant portion of electricity produced in the US over the last 39 years. Since the first commercial nuclear plant at Shippingport, Pennsylvania, started producing power in 1957, 110 nuclear plants have been placed in service. This accounts for approximately 20% of the US electric power production. In some states the number is much higher: Illinois relies on nuclear power for approximately 70% of its electricity needs. The generation of electricity from nuclear power will start to decrease in the year 2005 due to a number of plants being taken out of service as they reach the end of their design life (EDL). As these nuclear plants approach their design basis life of 40 years, plant owners will be faced with strategic decisions concerning continued operation through license renewal, decommissioning, or repowering. Without license renewal 20 units totaling more than 14 gigawatts will reach EDL by the year 2010. Three basic options are available to nuclear utilities: (1) continued operation through nuclear license renewal beyond EDL; (2) shutdown and decommissioning at EDL; (3) continued operation through nonnuclear repowering. This paper briefly reviews license renewal and decommissioning issues. Its primary focus is on the feasibility of Optionmore » 3 by reviewing the conceptual technical requirements for nonnuclear repowering and its associated economics.« less


The German Federal Ministry of Education and Research (BMBF) aims at promoting science communication in a more targeted way. This fits to a recently published demand by the German Science Council (Wissenschaftsrat), which would like to see more science communication from psychologists working in science. To be able to promote science communication, it is necessary to establish how and how much scientists are involved in science communication. We present a survey among German-speaking psychologists working in science (N = 740). The results show that German-speaking psychologists were less frequently engaged in science communication than researchers in other countries. As the main reason for science communication, respondents stated that science communication was fun and that they felt an obligation to communicate science to society and taxpayers. Lack of time, low prioritization, and doubts about one's necessary competence were rated as the strongest inhibiting factors. More institutional support for administrative tasks and teaching activities were the most frequently listed wishes to promote science communication. In the discussion, we put these findings in context with prior international surveys and consider possibilities to promote science communication.


This text deals about the close link that has been established between sport and securityin proposing social projects in sports. In a diagnostic of the present, had described"political conditions productive" observed in the state and region to strengthen theconnection type displayed - sports-safety. This relation is intended as a justification toreduce crime and violence "PELC-PRONASCI", from appearing on the website of theMinistry of Sports. After, discuss what is becoming as a "society of project" where thiskind of linkage, among others, are established.


A factor analysis reveals that the comprehensive competitiveness of Hebei medical industry in 2007 takes the 10th place,at the third national rate.Hence the paper argues for investment in high technology and creativity of Hebei medical industry to enhance the school-enterprise cooperation,marketing and exportations.


A high precision rotating disk apparatus (RDA) is designed and employed to investigate the turbulent drag reduction characterization induced by polymeric additives. For the past few decades, polymers have been used widely as drag reducer agents in a pipeline and RDA successfully due to its viscoelastic properties that can suppress the turbulent at high ranges of Reynolds number. In this study, drag reduction efficacy of diesel fuel in a rotating disk apparatus is investigated using high molecular weight polyisobutylene polymer as drag reducing agent. Dependence of drag reduction on different parameters such as: polymer concentration and rotational disk speed (RPM) are also investigated. In addition, the mechanical stability of this polymer with time was studied by measuring torque values for 300 sec at a fixed rotational speed (2000 rpm). It was observed that the drag reduction of diesel fuel increases withthe rotational disk speed and polymer concentration till a critical concentration at which the maximum drag reduction achieved. The maximum DR obtained was about 19.197% at Re = 902062 and PIB concentration of 150 ppm.


This article proposes and analyses distributed, leaderless, model-independent consensus algorithms for networked Euler–Lagrange systems. We propose a fundamental consensus algorithm, a consensus algorithm accounting for actuator saturation, and a consensus algorithm accounting for unavailability of measurements of generalised coordinate derivatives, for systems modelled by Euler–Lagrange equations. Due to the fact that the closed-loop interconnected Euler–Lagrange equations using these algorithms are non-autonomous, Matrosov's theorem is used for convergence analysis. It is shown that consensus is reached on the generalised coordinates and their derivatives of the networked Euler–Lagrange systems as long as the undirected communication topology is connected. Simulation results show the effectiveness of the proposed algorithms.


Abstract In real life, a person may assume that an object belongs to a set, but it is possible that he (she) is not sure about it. In other words, there may be hesitation or confusion whether an object belongs to a set or not. In fuzzy set theory, there is no means to incorporate such type of hesitation or confusion. A possible solution is to use intuitionistic fuzzy set [K. T. Atanassov, Intutionistic fuzzy sets, Fuzzy Sets Syst. 20 (1986), 87–96]. In this article, the concept of unbalanced fully fuzzy multi-objective capacitated solid minimum cost flow (SMCF) problems is generalized by unbalanced intuitionistic fully fuzzy multi-objective capacitated SMCF (CSMCF) problems and new methods are proposed for solving these problems. The main advantage of the proposed methods over the existing methods is that all the unbalanced fully fuzzy single- and multi-objective CSMCF problems that can be solved by the existing methods can also be solved by the proposed method.


The case of maternal mortality in Bandar Lampung city in 2013 is 19 cases, in 2014 there are 7 cases and all died during childbirth and there are 19 cases of maternal death by 2015. (Profile of Lampung Province Health Office 2014). Research Objectives to Detect the Influence of Vulva Hygiene Technique on Number of Vulva Germs In Nifas Mother In BPM Bandar Lampung City Year 2016. This research method using quasi-experiment design. This study compares between treated groups and control groups. Treatment group 1 was treated with vulvar hygiene by using 1 cotton, group 2 using 3 kinds of cotton, group 3 using 5 cotton and control group without treatment. Population in this research is mother Nanyang checking his health at BPM in Bandar Lampung city at the time of research. The sample of respondent's research is 120. Data collection with Teradata is done as much as 1 time then done culture and examination in a local laboratory. Data were processed and analyzed by independent T-test. The result showed that the average number of germs was 2277,37 germs (95% CI 7140,59-38402,16) with standard deviation 65553,94 germs. The lowest number of germs and pathogen bacteria still 0.35% of respondents on the vulva hygiene of a cotton with a duration of 26 days. The result of analysis with cruciate Wallis test is 3,498. Looking at the statistics of the table by looking at the Chi-square table, for df (degrees of freedom)=3 and the significance level (α) = 5%, then obtained statist table 2.32. Because of the count statistic (2.32> 0.321), then Ho accepted, or no significant difference (significant). The research unit can utilize and apply vulva hygiene technique with antiseptic, so it can prevent the occurrence of infection in the postpartum mother.


I would like to make a comment on Drs Burgess and Shuttleworth's letter on snakes and snake bites (Atiaesthesia, 1977,32,664). When I was in India in the RAMC between 1916 and 1919 I had an excellent book on snakes (written by Major Wall, I think) in which it was stated that each kind of snake had its own individual arrangement of scales (scale pattern); all types were clearly illustrated i n the book. Thus, as with finger prints, no type had the scale pattern of another type and, as each type always kept its own scale pattern, the identification of type was easy. I had to treat only one bad snake bite (cobra o r Russel's viper, not Krait as that was invariably fatal) and the patient was very ill for some I2 h or so and then recovered. I feel that I must also draw attention to the error in the Editors comment 'Editorial nostalgia for real time'. Rupert Brooke's last line in 'The Old Vicarage, Grantchester' (the '1' was omitted) is 'And is there honey still for tea'. The addition of 'shire' to Cambridge also breaks the scansion in the other line quoted-a pity.


The Group 4 image code is a two-dimensional coding scheme standardized by CCITT to compress black and white picture. Existing decompression algorithms process the compressed data bit-by-bit. The purpose of this project is to design and algorithm to speed up the decompression of group 4 image data


Mr Leto tells about his relationship to Aisoli (elder brother) and clarifies the ancestoral background of Aisoli Salin's family and the chief status.


1 Abstract Here we present MACRO-APE and PERFECTOS-APE software designed for practical sequence analysis involving classic mononucleotide and dinucleotide position weight matrices (PWMs) of DNA sequence patterns often called motifs. The common usage case for DNA motifs is representation of transcription factor binding sites. The software allows (1) comparing different PWMs using a variant of Jac-card similarity measure, e.g. scanning a motif collection for motifs similar to a given query, (2) analysing single-nucleotide variants for possible regulatory effect through transcription factor affinity changes, (3) performing basic PWM analysis (P-value and threshold estimation). 2 Technical notes MACRO-and PERFECTOS-APE require Java Runtime Environment 1.6 (or newer) to run. Thus *-APE should be able to function under most modern operating systems. Several existing motif collections such as HOCOMOCO as well as several individual PWM examples are available to be used with the *-APE package: HOCOMOCO [http://autosome.ru/HOCOMOCO/] TFBS model collection and several examples of PWMs (motifs) can be downloaded with MACRO-PERFECTOS-APE at


People-orientation is the forever theme for Taoism.The belief"Human Are Born to be Good"is taken as its education method,penetrat- ing among other methods.It roots from the Theory of Natural Humanism, and emphasizes the inaction of the nature.The belief"Human Are Born to be Good"has referential value and implication significance to the develop- ment of modem ideology education theory and practice.


Barbara Riedmuller considers poverty as a crisis of the family, and the repercussions for the division of domestic labour. She shows the inadequacies of official assumptions in this area. Michael Regus and Peter Trent-Hinterberger reflect on the case of the elderly and the impact of the privatization of institutional care for the aged. Ernst von Kardoff and Elmar Koenen consider possibilities for self-organization of the poor. Bernd Schulte contributes international and comparative perspectives, focusing on countries which have developed concepts of a minimum wage. The book is rounded off with a valuable forty-page bibliography. Although some of the contributions tend to abstraction, this helps to build up a theoretical analysis of the Sozialstaat and of the gaps between theory and the grim realities of poverty. Underlying the book are many chilling analogies between the 1980s and the 1930s. The editors observe that most legal and fiscal measures in social and wages policy have their precedents in the 1930s. The attack on the social insurance system as a cause rather than a victim of the economic crisis is a common feature of both eras. As Britain moves towards a social market, this book illustrates the pitfalls we can expect. PAUL WEINDLING Wellcome Unit for the History of Medicine University of Oxford.


Silicon carbide MESFETs with 0.7 /spl mu/m gates and 18 mm of total periphery had a P/sub 1db/ of 15 watts CW at 2.1 GHz with a power-added efficiency of 54%. These FETs were optimized for S-band power and had an f/sub T/ of 8.5 GHz and an f/sub max/ of 25 GHz. Similar devices with 0.45 /spl mu/m gate lengths had an f/sub T/ of 22 GHz and an f/sub max/ as high as 50 GHz, demonstrating the potential of this technology to extend to much higher frequencies.


Since the early 1990s the countries of Southeast Europe have looked to NATO not simply as a security organization, but as the harbinger of a new era of stability, sustainable development and democratic prosperity in the region. Now, some of them are already NATO members, while others are on their way to membership. On May 2003, three NATO partner countries, Albania, Croatia and Macedonia, collectively signed a Charter of partnership with the United States of America, the Adriatic Charter (A3). It was a commitment on the part of the three countries to intensify reforms and mutual cooperation aimed at integration in NATO. Since then, the Adriatic Charter (A3) countries have collaborated at different levels of security and have collectively participated in NATO-led peace-keeping mission in Afghanistan. At the last summit in Riga, the heads of countries and governments of NATO members noted the progress of the Adriatic Charter countries in their joint declaration. Honoring the commitment of our peoples to join the Euro-Atlantic community, and looking forward to the possibility to fulfill their historic aspiration at the next NATO Summit in Washington, the Institute for International Relations in Zagreb, Croatia, the FORUM Center for Strategic Research and Documentation in Skopje, Macedonia, and the Institute for Democracy and Mediation in Tirana, Albania, as civil society organizations, have joined together in the Civil Alliance 08. This is an initiative for opening up the processes of NATO integration to our societies and region at large and for stimulating the non-for-profit sector in A3 countries to take relevant responsibilities and to be active partners of governments in the Euro-Atlantic integration. Civil Alliance 08 promote A3 framework as a platform for regional integration and political and security cooperation and for catalyzing reforms. The Civil Alliance also work in partnership with the governments of Croatia, Macedonia and Albania in support of their international efforts to increase the visibility of our reform efforts and gain support for NATO membership. In cooperation with governments and national and international organizations, the Civil Alliance 08 support and coordinate the efforts of civil society in the region, as a yet not institutionalized dimension and complimentary component of the Adriatic Charter. Each of partnering organization commits itself, under the auspices of the Civil Alliance 08, to coordinate nationally a " Framework for Action" for non-governmental organizations that will promote their synchronized, long-term commitment to monitor and advance the principal standards for the Euro-Atlantic integration of our countries: strengthening of democratic values, fighting corruption and organized crime, security sector transformation and fostering good neighborly relations and regional cooperation.


Population. In the second half of the 20 th Century the population of the Americas grew from 400 million to 800 million inhabitants. According to CEPAL (Pinto da Cunha, 2002), by the year 2000 South and Central America, Cuba, Haiti, Jamaica, Mexico, and Dominican Republic amounted to 75% of urbanization. Argentina, Brazil, Colombia, Mexico, and Peru recorded the highest rates of population and growth during the 1950-1990 period. The topic of rural population is very important, mainly in Central America, where 35% of the population lives in rural areas. Percentages above this value are found in Haiti (65%), Guatemala (61%), El Salvador (54%), Costa Rica (52%), Paraguay (45%), Jamaica, and Panama (44%), Honduras (41%), Nicaragua (44%), and Bolivia (38%). Whereas it is a slow process, the total population and its urban fraction are increasingly growing in LAC. The Assessment 2000 (PAHO, 2001) showed that during the 1990s, the population grew from 429 to 497 millions.


FIELD: cellulose layers for shielding electric and high-frequency fields. SUBSTANCE: thin electricity conducting cellulose layer capable of shielding electric and high-frequency fields is 30 to 80 mcm thick, it weighs 20 to 60 g/sq. m, and incorporates 95-100% of carbon and cellulose fibers in terms of absolutely dry weight, proportion of carbon fibers, 1 to 15 mcm in diameter and 1 to 29 mm in length, being 4 to 20 mass percent in terms of absolutely dry weight and proportion of cellulose fibers, 75 to 96 mass percent in terms of absolutely dry weight. Layer is noted for high electric conductivity and ability of shielding electromagnetic fields with added advantage of excellent permeability for steam. Layer can be easily included in pressboard composition. Layer and pressboard sheet are suited to use for standard materials of floors, walls, and ceilings, gypsum and concrete slabs. EFFECT: enhanced ability of shielding electric and electromagnetic fields, facilitated handling, reduced cost. 6 cl, 5 tbl, 3 ex


Four-dimensionalism, as I'll use the term, is the doctrine that reality is spread out in time as well as space.1 Just as objects that are located at multiple regions of space contain parts con ned to those regions of space, so objects that are located at multiple regions of time contain parts — temporal parts — that are con ned to those regions of time. (Or better: an object that occupies an extended spatiotemporal region R has parts con ned to the various subregions of R; but I'll ignore this complication henceforth.) Most who accept this ontology of perduring objects, as they are often called, identify the continuants of our everyday ontology with "space-time worms" — mereological sums of stages from different times. Elsewhere (1996) I have proposed a different version of four-dimensionalism, which identi es continuants with the stages themselves, and which analyses de re temporal predication with a temporal version of modal counterpart theory (Lewis, 1968, 1971). On this view, a current assertion of 'Clinton was indiscreet' is true iff the (current) referent of 'Clinton' — a stage — has an indiscreet temporal counterpart in the past. The temporal counterpart relation is the same "genidentity" or "unity" relation used by the worm theorist to unify the successive stages of continuing space-time worms. In my 1996 I supported this view by appeal to its ability to resolve various philosophical puzzles, including the paradoxes of material constitution and Derek Par t's (1971) puzzle about identity and what matters; the purpose of the present note is to mention one other line of argument. A widely discussed contemporary argument for temporal parts is David Lewis's argument from temporary intrinsics, according to which only the fourdimensionalist can explain the phenomenon of intrinsic change.2 I am now straight-shaped, but will fail to be straight-shaped in the future. There is an


The latest changes that have taken place across our Western frontier are full of grim portents for Pakistan. Dominance of the Soviet Union in Afghanistan has considerably influenced the political geography of the region. Pakistan's geographic location in the strategic zone of the Middle East Oil and the Afro-Asian Ocean is of considerable importance. In the context of its global strategy, the Soviet Union has vital strategic, political and economic interests in the region. As such, it is incumbent upon Pakistan to be vigilant at all times, and adopt a pragmatic and rational approach towards its neighbours.


Microservices represent a new architectural style where small and loosely coupled modules can be developed and deployed independently to compose an application. This architectural style brings various benefits such as maintainability and flexibility in scaling and aims at decreasing downtime in case of failure or upgrade. One of the enablers is Kubernetes, an open source platform that provides mechanisms for deploying, maintaining, and scaling containerized applications across a cluster of hosts. Moreover, Kubernetes enables healing through failure recovery actions to improve the availability of applications. As our ultimate goal is to devise architectures to enable high availability (HA) with Kubernetes for microservice based applications, in this paper we examine the availability achievable through Kubernetes under its default configuration. We have conducted a set of experiments which show that the service outage can be significantly higher than expected.


Abstract An approximate analytical solution of Richards' equation (RE) in a semi-finite layer of porous medium is obtained in this article. The basic idea is constructing a function between the Boltzmann variable ϕ and the traveling wave solution of RE, introducing the function into RE and calculating the relevant parameters by differential transform method (DTM). In the end, three examples are prepared to show the accuracy of the presented approximate analytical solution.


Abstract Exogenous fibrolytic enzymes (EFE) added to the ruminant diet can increase fiber digestibility and production efficiency. A systematic review was conducted to understand the interactions between EFE and diet on digestibility and animal performance. The database included variables from 384 experiments with EFE and 264 controls from 85 papers published since 2000 (classification criteria: 1) type of study (in vitro, in situ, in vivo), 2) type of ruminants (sheep, buffaloes, goats, beef and dairy cattle), 3) primary EFE activity (cellulases (Cel) or xylanases (Xyl)), 4) forage proportion (FP), 5) type of plant (TP: legumes or grasses), 6) number of ingredients in diets, and 7) application time (AT)). In over 52.85% of cases, EFE improved the degradability of dry matter (DMD), neutral and acid detergent fiber (NDFD and ADFD), in vitro gas production (GP), volatile fatty acids (VFA), the acetate: propionate ratio (A:P ratio), protein and fat milk, milk yield and average daily gain (ADG) (by 7.78–21.85%). Cel improved organic matter degradability (OMD), GP, VFA, milk yield, and milk protein and fat content. EFE in FP≥40% diets enhanced the ADG, and in grassbased diets increased the dry matter intake (DMI). The AT of EFE affected the DMD, NDFD, and ADFD. Significant correlations were found between the improvements of NDFD or ADFD with DMD (r>0.59), milk yield (r=0.64), and ADG (r=0.59). In conclusion, many factors interact with EFE supplementation effects, but EFE consistently enhanced the DMD, NDFD, and ADFD of ruminant diets, which are related to improvements in productive performance.


Objectives: This study aimed to observe the decrease in tooth color after home and office bleaching due to consumption of juice, soda, and coffee over a period of one year. Methods: We obtained written consent from 30 subjects, who were divided into two groups i.e., home bleaching and office bleaching groups. They were treated with opalessence® and Zoom2 whitening gel, and the color of their teeth was assessed using shade Eye-NCC over a one-year period. A self-describing questionnaire was used to determine the frequency of juice, soda, and coffee consumption. Results: The changes in color were measured before and after 1 day, 1 month, 3 months, 6 months, and 12 months. Although the tooth color slightly changed after 12 months, the teeth were brighter than the original color. Consumption of juices, sodas, and coffee is thought to be associated with decrease in tooth color, although the change was not statistically significant. Conclusions: The ΔE* values showed that the tooth bleaching effect remained for 12 months. Consuming a normal amount of juice, sodas, and coffee does not significantly reduce tooth color after tooth bleaching.


Hizikia fusiformis hydroysates by five carbohydrases (Viscozyme, Celluclast, Termamyl and Ultraflo) and five proteases (Protamex, Kojizyme, Neutrase, Flavourzyme and Alcalase) were investigated for their extraction efficacy (yield and total total polyphenolic content) and antioxidative activity (DPPH radical and hydrogen peroxide scavenging activity). Termamyl and Ultraflo of the carbohydrases and Flavourzyme and Alcalase of proteases were selected by their high eficacy of extraction and antioxidative activity. Selected enzymes were used to investigate the optimum enzymatic reaction time and dosage (enzyme/substrate ratio) suitable for hydorolysis. Optimum reaction time for the enzymatic hydrolysis was 3 days and optimum dosage of hydrolysis was observed as 5%. Simultaneously, Ultraflo of the two carbohydrases and Alcalse of the two proteases were selected as the most effective enzymes. Combination of Ultraflo and Alcalase under optimum hydrolysis conditions could intensify the extraction efficacy of antioxidative materials form H. fusiformis. The hydrolysate obtained by combining the enzymes was separated into four different molecular weight fractions (30 kD) and recorded the polyphenolic content distribution and respective antioxidative ability. The fraction 1kD indicated comparatively higher antioxidative activities related to their polyphenolic content.


The past several years have seen dramatic progress in our understanding of the reactions taking place in the early events of photosynthesis. This has been in large part due to research involving purple photosynthetic bacteria ([16][1], [28][2], [34][3], [35][4],[46][5], [56][6]). These anaerobic


In a business process, the customer's position becomes very urgent because, in the end, the output comes down to the customer. It is customers who judge according to their perceptions and expectations, whether the service they receive is quality or not. Therefore, developing service quality through inspection of business process models must be done regularly. One of the theoretical tools that can be used to examine and develop service quality through the business process model applied by an organization is the six imperative stages of Pall (1987). Research conducted at a government hospital in Makassar City, Indonesia shows that although it does not carry out investigations in the context of developing service quality regularly, this organization can show significant achievements through obtaining several awards from the government. However, in order to maintain and maintain good service performance, the analysis based on the six key prerequisites for checking the quality of service through this business process model shows that in order to maintain and maintain the service performance achievements of this organization, it is necessary to carry out inspection and improvement at this stage; (1) Measurement, namely mapping the performance of attributes to customer needs and establishing criteria for accuracy, precision and frequency of data acquisition; (2) Renewal or Improvement, namely increasing the effectiveness of the process through improvements that are permanently identified; and (3) Optimization, namely increasing efficiency and productivity through developments that are identified definitively.


The sudden short lived perturbation in geomagnetic variation in the sunlit hemisphere concurrent with the occurrence of a solar flare referred to as 'Solar flare effect' (SFE) or 'crochet' is rather a well-studied aspect in the field of solar-terrestrial relations ever since it was discovered that chromospheric eruptions, short wave fade-outs (SWF's) and SFE's were all concomitant phenomena (DELLINGER, 1935, 1937a, b; FLEMING, 1936; RICHARDSON, 1936; TORRESON et al., 1936a, b). It is now known that the occurrence of SFE is a maximum around local noon and its amplitude has a local time variation similar to that of Sq field (MCNISH, 1937; NAGATA, 1952; SUBRAHMANYAM, 1964; PINTER, 1967). Evaluation of ionospheric current systems during flare times revealed that SFE is not due to a mere augmentation of normal Sq field as thought of by CHAPMAN (1937, 1961) and CHAPMAN and BARTELS (1940); and the current flowing layer responsible for SFE is below the normal dynamo current carrying region (VOLLAND and TAUBENHEIM, 1958; VELDKAMP and VAN SABBEN, 1960; YASHURA and MAEDA, 1961). An interpretation of SFE in terms of enhanced electrical conductivity due to solar X-ray flare flux enhancement in the band 1-20A was made by OHSHIO (1964) from a study of selected SFE events observed during I. G. Y. A recent study indicated that SFE is due to extra ionization produced by solar XUV (1-1000A) flare radiation and the SFE's often exhibit a composite structure consisting of a 'fast' component presumably due to EUV radiation (100-1000A) and a 'slow' component produced by soft X-rays (1-100A) (RICHMOND and VENKATESWARAN, 1971). A very recent study made by the authors using SFE's observed (on normal run magnetograms) at Kodaikanal (Lat: 10.20N; Long: 77.50E, Dip: 3.50N) showed that the amplitude of SFE is linearly correlated with peak solar X-ray flux level in the bands: 1-8A and 8-20A (monitored by SOLRAD-9) lending support to the interpretation that SFE is due to enhanced ionization produced by solar soft X-rays (SASTRI and MURTHY, 1975).


Refrigerators have been used since long time ago to
preserve perishable foods. Nowadays it becomes one of the essential appliances in a household. Today's refrigerators use much less energy as a result of using smaller and higher efficiency motors and compressors, better insulation materials, larger coil surface areas and better door seals. However, the basic vapour-
compression refrigeration cycle has remained unchanged. The condenser coil at the back of the refrigerator dissipates heat to the surrounding. As long as the refrigerator is on, the condenser coil will continuously dissipate heat to the surrounding air. This
project is to utilize the heat from condenser to warm the oven compartment. The condenser coil is modified to enter oven compartment before return back to existing coil. The temperature distribution from the condenser to oven compartment was investigated through experiment. The analysis of the refrigerator performance is also done to study the effect of modification to the
refrigerator. The heat can be used to develop low temperature oven at the top of the refrigerator. The oven is not required any electrical heater. The results show that the heat is capable to warm the oven compartment more than 63°C. However, the electricity consumption increases because the compressor has to
work hard to force the refrigerant flow in the longer condenser coil. There are still a lot of improvements need to be done in order to improve the oven and refrigerator performance.


Objective To investigate the ratio of L-form of Mycobacterium tuberculosis (TB-L) infection in recur- rent pulmonary tuberculosis (TB) patients and its effect to pulmonary lesions and epidemic situation of tuber- culosis.Methods The X-ray chest films of the recurrent pulmonary tuberculosis patients were photographed in situ and analyzed,and the patients' morning sputum were cultivated for TB and TB-L.Results There were 92 TB-positive cases in 260 recurrent pulmonary tuberculosis patients.In 92 TB-positive cases,32 TB-L positive cases were detected with positive detection rate of 34.8%.There were 45 TB-L positive cases in 168 recurrent pulmonary tuberculosis patients whose sputum were tuberculosis negative and the TB-L positive detection rate was 26.8%.The data also demonstrated that the pulmonary lesion extent of both TB and TB-L detection posi- tive patients was more extensive than those both negative patients (x~2=6.44,P0.05).Additionally pul- monary cavity significantly increased in both TB and TB-L detection positive patients (x~2=31.63, P0.01).Conclusion These results suggest that TB-L could be detected in TB positive or TB negative pa- tients.TB co-infection with TB-L may aggravate bilateral pulmonary lesions and increase cavities.There are 26.8% TB-L positive patientsin TB negative patients,therefore their treatment and impact on epidemic situa- tion should no be,igrored.


Renewable energy resources such as wind energy have a disadvantage that the quality of output power is lower than that of fossil fuel resources. To solve this problem, pumped storage power system with Archimedean screw is designed. The structure and principle of operation are introduced and the advantages and disadvantages are discussed according to the theory and the simulation. In this paper, comparison has been done by collecting and analyzing the data and simulated the system on different condition to show the differences of the two types of pumps working on the pumped storage system.


A plant-incorportated protectant (PIP) is a pesticidal substance produced by a gene that has been inserted into a plant through transgenesis. EPA does not regulate the plant; in contrast to other regulatory agencies, we regulate the gene and the gene product. As pointed out by Roger Beachy1, the definition of a pesticide has been around since 947, when the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) was promulgated. In addition to language about destroying, repelling, and/or mitigating pests—"pests" are defined in the statute—it deals with plant regulators (not plant-growth regulators). Admittedly the category is broad, but then "pesticide" is difficult to define. As far as I know, there is no inclination or intention to regulate plants expressing plant-growth regulators as pesticides, although, certainly, a policy statement to that effect might be helpful. Today, I am speaking specifically about plants that are diseaseand/or pest-resistant. Four statutes influence our authority to regulate PIPs (Figure ) of which I will focus on FIFRA, the main pesticide law, and the Federal Food Drug and Cosmetic Act (FFDCA) that we share with our colleagues at the Food and Drug Administration (FDA) regarding residues and tolerances. FIFRA is unusual in terms of environmental statutes in that it considers benefits as well as risks, which is crucial with compounds that are inherently more toxic—typical nematicides, insecticides, etc., for example—but it can apply to PIPs in terms of environmental safety or benefits and even economic safety and benefits. This does not apply to the Food Drug and Cosmetic Act. Regulation of Plant-Incorporated Protectants by the US Environmental Protection Agency


Research on Vygotsky's zone of proximal development theory was used as a foundation to investigate differences in the learning and transfer ability of 30 students with learning disabilities (LD) and 30 students with matched low achievement (LA), from grades 7 and 8. The two groups were assessed on their problem-solving ability on a balance scale learning task and three transfer tasks under unassisted and assisted conditions. Analyses were conducted to determine group differences in performance on several measures of learning, transfer, and maintenance. Results indicated inconsistent performance differences between the two groups. Students with LD performed similarly tc students with LA on measures associated with the learning task, but generally outperformed students with LA on measures associated with the transfer task. It is concluded that students with LD are more capable than students with LA of maintaining and transferring their learning, suggesting that the ability to transfer learning is more closely related to general intelligence than to a specific learning disability. (30 references) (JDD) ************************************.c************* ****************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** Difference. in Transfer Propensity and Learning Speed on Balance-Scale Problems for Students with Learning Disabilities and other Low-Achieving Ezudents U S DEPARTMENT OF EDUCATION p I du. al LOW HPStfah h an(1 I tioCAtiONAL RI SOURCE S !NE ORMATION ptt 1,om tflp e,s(Th ci organaalon .o.g.natasy Mary T. Brownell : M..1). bangio. have boon mark. lo .mtwOve ,rI,,COLic Nan Quilidy _ University of Florida p..,,0,0,..0. or,,ons staled as PIA no( o mem .1c no! npcp%Satay ,plitesenr orfloal Of RI gujt...I.on 0. Daryl F. Mellard, Donald D. Deshler University of Kansas InstLite for Research in Learning Disabilities


Persistent Pulmonary Hypertension of the Newborn (PPHN) is defined as a failure of the normal circulatory transition after birth. PPHN manifests as a progressive and potentially fatal hypoxemic respiratory failure. The condition is associated with a persistent increase in pulmonary vascular resistance and reduced blood flow in the pulmonary vessels without an accompanying congenital heart defect. The abnormalities in pulmonary circulation lead to right-to-left shunting through the foramen ovale and usually also through the ductus arteriosus, with resultant hypoxemia, which manifests clinically as cyanosis. Management options in PPHN include optimal lung inflation, oxygenation, prevention of acidosis, stabilization of blood pressure, sedation and pulmonary vasodilator therapy. While inhaled nitric oxide (iNO) is the most commonly used treatment option, alternative methods can be used whenever is unavailable or contraindicated. We report three cases of severe PPHN, in which due to the lack of adequate response to intravenous MgSO4, the patients were switched to milrinone.


To understand the chemical changes in the streamwater and contribution of subsurface discharge during the storm event, we analyzed electric conductivity (EC), anions, and cations in Gwangneung deciduous and coniferous forest catchment. The stream water samples were collected three times in 2004 by using an auto-sampler: September 7-9 (E040907-D and -C; where D and C indicate deciduous and coniferous forest catchment, respectively), September 11-13 (E040911-D and -C), and September 16-18 (E040916-D and -C). We found a negative relationship between discharge intensity and EC in streamwater. The E040911 and E040916 showed slack change of stream discharge in comparison to E040907 due to contribution of base flow recharged by much precipitation. Moreover, NO/sub 3//sup -/ concentrations in E040911-C were highest, which may have resulted from forest management such as thinning in 2004. The relationship between pH and alkalinity in stream water showed that much of stream water have been recharged through subsurface. We conclude that subsurface discharge highly influences streamwater quality in a forested catchment, and the seperation of stream water discharge is therefore necessary to sustainable water management.


Summary The maintenance of highway trees undertaken by the Cardiff City Council on behalf of the Glamorgan County Council is described.


The present invention is 4 - [(3-chloro-4-fluorophenyl) amino] -6 - {[4- (N, N- dimethylamino) -1-oxo-2-buten-1-yl] amino} - 7 - ((S) - tetrahydrofuran-3-yloxy) - it relates to an improved process for the preparation of quinazoline and related amino crotonyl compounds. Furthermore, the present invention is for use as active ingredients in pharmaceutical preparations, 4 - [(3-chloro-4-fluorophenyl) amino] -6 - {[4- (N, N- dimethylamino) -1- oxo-2-buten-1-yl] amino} -7 - ((S) - tetrahydrofuran-3-yloxy) - on suitable salts of quinazoline.


The establishment of the Cobdogla Irrigation Museum was the major contribution of the Engineering and Water Supply Department of the South Australian Government to the State's sesqui-centenary celebrations in 1986. The main objectives were to conserve and operate various items of steam, gas and oil fired equipment, including a unique Humphrey Internal Combustion Pump, and display the irrigation history of the Region. The concept, planning and development of the museum are described.


This paper presents a hybrid control schleme for two cooperative robots and extends the approach of hybrid position/force control for one single robot to the case of co-operative robots. The two robots are assumed to be working on the same object with environment constraints. The generalized task specification matrices are used to divide the operational space into two independent subspaces, a position control subspace and a force control subspace. The position and force control of two cooperative robots is achieved, respectively, in the two orthogonal subspaces without influences each other. Finally we study the robustness of the hybrid control scheme proposed due to the presence of parametric uncertainty and model errors.


The purpose of this study is to identify the needs which are perceived by one of the familiy members who have head injury parients by traffic accidents in the intensive care units. Subjects were 70 families members of head injury patients admitted to 2 general hospitals NICU located Pusan city, 1 general hospital NICU located Ulsan city from December 1. 1998 to February 28. 1999. For this study, 70 family members were interviewed with aid of a Likert scale which was developed by researcher for this study. For development of the survey instrument, literature review and open questionnaire technique with family members and the nurses working in NICU. The 50needs-items were classified into 7 groups according to the homogeneity of the items with the support of literature review. For the content validity, the instrument was reviewed by 1 nursing professor and the internal reliability of this instrument was Cronbach alpha=0.94 which is highly accepted. Data was analyzed by a SPSS computer program. Data analysis included frequency. percentage, mean, standard variance and t-test or ANOVA. The results were as followings : 1. The general characteristics of head injury patients shows that the male was 74.3%, the female was 25.7% and age distribution shows that the fifty-fifty nine years was 30%, the highest. Of religion the buddhism was the most, The diagnosis distribution shows that epidural hematoma was 32.9% and subdural hematoma was 24.3%. The mentalility distribution shows that semicoma was 31.4% and stupor was 31.4%. Hemiplegia was 42.9% 2. The general charaterisrics of the family needs of head injury patients shows that thirty-thirty nine years was 31.4%, the highest. sex distribution shows that the male was 20%, the female was 80%. Of religion the buddism was the most. 3. The family needs of head injury patients was , needs for the information of a patient's condition was , the highest. And needs for the information of care and treatment was , needs to be supplied with comfortable facilities for family was , needs to be participate in a patient's care was , needs to be informed about the available resources was , needs to be supported emotionally for family was , needs for religious assistance was . 4. Examining the family needs of head injury patients according to patient's characteristics, mentality, plegia degree and operation were shown be variables to make an effect on the needs for the head injury patients family. At all, according to severity of head. injury, the family needs of head injury patients was high. 5. Examining the family needs of head injury patients according to their general characteristics, we could know that religion, job. income were shown to be variables to make an effect on the family needs. Through the examination it can be seen that the characteristics of head injury patients and the family needs of head injury patients. In conclusion, the family needs of head injury patients was almost same the family needs of ICU patients. Therefore we must involve the family's care of head injury patients and we must provide exact and repeated explanation, education and support the family of head injury patients. As this study was resulted in selecting the families admitted to NICU of some general hospital, we couldn't stretch the result in our favor. Therefore, continuous studies are suggested.


Evaluation of key performance indicators (KPIs) such as energy consumption is essential for decision-making during the design and operation of smart manufacturing systems. The measurements of KPIs are strongly affected by several uncertainty sources such as input material uncertainty, the inherent variability in the manufacturing process, model uncertainty, and the uncertainty in the sensor measurements of operational data. A comprehensive understanding of the uncertainty sources and their effect on the KPIs is required to make the manufacturing processes more efficient. Towards this objective, this paper proposed an automated methodology to generate a hierarchical Bayesian network (HBN) for a manufacturing system from semantic system models, physics-based models, and available data in an automated manner, which can be used to perform uncertainty quantification (UQ) analysis. The semantic system model, which is a high-level model describing the system along with its parameters, is assumed to be available in the generic modeling environment (GME) platform. Apart from semantic description, physics-based models, if available, are assumed to be available in model libraries. The proposed methodology was divided into two tasks: (1) automated hierarchical Bayesian network construction using the semantic system model, available models and data, and (2) automated uncertainty Manuscript received September 1, 2016; accepted for publication March 24, 2017; published online


Abstract : According to its basic doctrine, 'The Air Force is responsible for the preparation of the air forces necessary for the effective prosecution of war and military operations short of war... and... for the expansion of the peacetime components of the Air Force to meet the needs of war.' Preparation of the necessary air forces means to 'organize, train, equip, and provide forces' to carry out all the operations required to fulfill the Air Force's primary and collateral functions (now, more commonly called 'missions'). Throughout the Cold War, the forces 'necessary for the effective prosecution of war' clearly dominated over the other two responsibilities. The Cold War threats required ready forces that were capable, if necessary, of prosecuting a war to termination in hours or days. The immediacy and high stakes of those threats made mobilization for war and operations short of war lesser considerations. So, for more than 40 years, the efforts to 'organize, train, equip, and provide forces' focused on 'the effective prosecution of war,' while operations and mobilization short of war were handled as issues on the margins of Mr Force priorities. That Cold War focus may be contrasted to the peacetime, pre-World War II era when the emphasis was on mobilization and operations short of war.


Ions trapped by electron beams in the rings oscillate with a certain frequency in the beam potential. The oscillation, which is incoherent at the early stage, becomes coherent and shakes the beam with a frequency. This is the mechanism of the ion instability. We investigate the fast-ion instability in the two proposed International Linear Collider damping rings of OCS6 and FODO4 with a high intensity and a low-emittance in which the growth rate may be very rapid. We have performed a simulation based on the weak-strong model and analytical estimate to investigate characteristic phenomena of the fast-ion instability that is a critical issue in the damping rings. We investigated the effects of the ion frequencies, bunch filling patterns, vacuum pressures, and a feedback system on the fast-ion instabilities in the damping rings. The interactions between ions and beams in our simulations were performed using the magnetic components of the damping ring. The simulation results show that the bunch-by-bunch feedback of about 50 turns is sufficient to suppress the fast-ion instabilities in the damping ring. It is estimated that the tune shifts in the beam due to the ions are small.


Objective To establish an experimental model of osteoblasts of newborn mouse in vitro,a procedure of osteoblast isolation and culture was developed,and the feasibility of this technique and its practical value were investigated.Methods Osteoblasts were isolated from fetal mice within 1~3 day.Collagenase digestion of the skull of fetal mice was conducted repeatedly,and the collected cells were cultured in vitro.The osteoblasts were identified by cell morphology,histochemical alkaline phosphatase(AlPase) staining and calcified nodules staining.The growth curve was recorded.Results Many cells showed adherence to the culture plat after 24 hours of cell culture.The cells were of round appearance.After 48 hours of cell culture,the appearance of cells became long fusiform,triangular or irregular polygonal and often had 2 or 3 projections.After 7 days,the cells grew in full flat plate undersurface.The cultured cells possessed biological behavior of osteoblasts.The growth curve showed that the first and second 24 hours were the adaptive phase,the third to the seventh 24 hours was log phase growth.Conclusion Repeatedly digestion of skull of fetal mice and culture of osteoblasts in vitro is a practical,efficient and effective method.


Most PLL research focuses on narrowband systems that support only one communication standard. For a flexible system, it may be desirable to support multiple standards. A single PLL capable of operating over a wide frequency range while meeting all the requirements of the individual standards can save area and design effort, compared with multiple PLLs each supporting only one standard. This thesis presents a PLL that has a very wide tuning range, accurate quadrature outputs, and is geared towards low phase noise. The VCO is identified as the limiting factor in the tuning range and source of the quadrature outputs, as well as the primary source of the phase noise above the loop bandwidth of the PLL, so its design is the principle focus herein. The VCO uses digitally switched capacitors to extend the tuning range. It consists of two cross-coupled cores that produce quadrature outputs, where phase error arises if the cores are not identical. The VCO's output also has a controlled amplitude and common mode point. The charge pump of the PLL is designed to compensate for variations in the VCO's gain at different frequencies. In simulations using a 0.13μm CMOS process, the VCO achieves a tuning range of 1.585-3.254GHz over process and temperature variations. Its quadrature outputs have less than 2.6 phase error for a 2% mismatch in the capacitance between the two LC-tanks. The phase noise, calculated assuming a linear, time-variant model, is -109.5dBc/Hz at 600kHz offset from 3.217GHz. Thesis Supervisor: Michael H. Perrott Title: Assistant Professor of Electrical Engineering Thesis Supervisor: Kimo Tam Title: Senior Design Engineer, Analog Devices


A generalised definition for invariance of partial differential equations is proposed. Exact solutions of the equations with broken symmetry are obtained.


Three recently published studies indicate that aspirin, already enjoying a second lease of life in the prevention of heart disease, may soon become a first line of defence against cancer.

Two prospective, placebo controlled studies published in the New England Journal of Medicine (2002:348;883-90 and 891-9) looked at patients at risk of colorectal cancer. Both studies found a clear benefit from aspirin in reducing the frequency of new colorectal polyps.

The second of these studies, led by John Baron of Dartmouth Medical School, Hanover, New Hampshire, followed 1084 patients with a history …


been locally occurred at the early formation stage of the rock-ice bodies including comets and icy asteroids. The repetitive warming process of ice might have promoted the formation of ten micron-sized large, nitrogen-rich organic material observed from D05IB80. Association of organic material and sulfur supports the presence of fluid chemistry on the parent body. These features appear to be a very pristine signature of interaction of mineral, ice, and organics in the primitive small body.


This paper explains an easy way to get rid of optical geometric distortion in digital images of planar objects, using Matlab common functions (in bold and italic). It is currently applied in images with resolution ranging from 40 to 1200 μm, in fields of view (FOVs) from 4 to 300 cm diameter, digital cameras BW can be used for 2D targets of any size, with appropriate reference distortion grids. As long as the observation geometry remains the same, the transform produced and saved to disk is valid and does not need to be repeated until camera position changed. Subsequent images can be corrected with one Matlab command.


Semiconductor interface investigation via analytical characterization represents a major focus for Failure Analysis and Process Characterization Teams. Investigation can be performed via destructive techniques through depth profiling until reaching the interface while collecting matrix and impurity distributions as a function of depth and also via nondestructive techniques which preserves information about the interface. Interface characterization involves the deployment of Failure Analysis resources, employing advance imaging and materials characterization techniques like TEM (transmission electron microscopy), SEM (Scanning Electron Microscopy), DSIMS (dynamic secondary mass spectrometry), TOFSIMS (time of flight secondary ion mass spectrometry), Auger, XRF (X-Ray Fluorescence), and XPS (X-ray Photoelectron Spectroscopy). As first exampled in the case study detailed in this paper, increased aluminum resistance was caused by oxidation of aluminum metal while in a cooling chamber prior to barrier layer deposition due to chamber lid atmospheric leaks. High resistivity interconnect issues can be related to interface quality and diminish product performance up to complete failure. Typical methods like cross section analysis via TEM and SEM did not reveal any abnormality. This prompted further investigation where innovative depth profiling methods of DSIMS / TOFSIMS to the encapsulated interface was used, highlighting the presence of oxidized aluminum metal. In another example, analysis was performed nondestructively utilizing a newly developed High Energy HAXPS mode, allowing for the successful characterization of interfaces and high electron mobility transistors where layer interaction is vital.


The MOSHFET design which combines the advantage of the MOS structure, which suppresses the gate leakage current, and an AlGaN/GaN heterointerface that provides high density, high mobility two-dimensional electron gas channel. This article presents a comparative review of the I-V characteristics, cut-off frequencies, RF output powers, power gain, and nonlinear distortions of AlGaN/GaN MOSHFET, and HFET device. The MOSHFETs possess significant advantages for the monolitic IC design. They sustain very high input impedance at elevated temperatures, even above 300 /spl deg/C. The results show that the MOSHFET based ICs are extremely promising for a large variety of high-power high-temperature applications.


The angiotensin-I-converting enzyme (ACE) inhibitory activity of f yogurt fermented with four lactic acid bacteria was investigated. The results found that the yogurt fermented with L. helveticus ATCC15019, 15009 and L. thermophilus ATCC14485 had the potent inhibitory activity on ACE. After the oral administration of the yogurt or its whey to spontaneously hypertensive rats (SHR) for three days, results showed that both of them had the antihypertensive effect, with the most decrease value of 24.10±2.69mmHg and 29.14±3.07mmHg of systolic blood pressure(SBP), which showed outstanding differences, compared with the control groups.


In his work the author considers the dilemma of discrimination in Czech Republic, especially the discrimination of elderly people ? ageism. In the theoretical part he explains the term discrimination, its various types and areas, in which discrimination is forbidden and last but not least also means of protection. In the practical part he compares ageist postures in years 2003 and 2007 with his own findings from year 2010.


The design of an autonomous underwater vehicle (AUV) involves complex tradeoffs among various design variables and mission requirements. Particularly important are the selection of a suitable energy source and the sensitivity of vehicle dimensional characteristics to mission requirements. A method of comparison based on an approximate but comprehensive approach which refers to specific parameters derivable from known designs or literature is suggested. Specific energy and energy density of candidate systems are derived with due consideration to depth-resistant vessels. The impact of the energy system choice is highlighted, going beyond simply comparing the former parameters. A design model has been developed, allowing quick sensitivity and mass-volume breakdown of alternative configurations under varying mission requirements; these are exemplified with reference to a design case. The procedure allows the correct specification of power, energy, and surface-handling systems for more detailed comparative analyses, given a common project goal and a basis for realistic cost comparison. The results show wide differences in the energy capacity of AUVs complying with identical mission data, but using with different energy systems. It is concluded that rechargeable electric batteries, even of high energy density, result in unacceptably heavy vehicles for ranges around 1000 km unless very low drag characteristics are achieved. Closed-cycle diesel and fuel cell systems allow the AUV mass to be kept below 10 t. >


Power reduction is one of the main reasons for designing asynchronous circuits. Asynchronous circuits are inherently capable of having low power consumption. In this paper, we introduce five metho ds to achieve even lower power consumption. We have applied these methods to some sample circuits and t he experimental results show that power reduction of 2 0% to 41% is obtainable.


Abstract The aim of this research is to investigate the effectiveness of the "Group Counselling Program to Reduce the Social Anxiety" developed with the aim of reducing the level of social anxiety of candidate teachers in the final year of university. Quasi experimental design with Pretest-Post Test and Control Group was used in the research. 28 voluntary students studying in the Departments of Guidance and Psychological Counselling and Early Childhood Education were the sample of the research. "Social anxiety" measurements formed by "social avoidance, being criticized and individual worthlessness" points before and after the implementation of the program, have been compared by using t-test and it has been determined that the social anxiety decreased significantly in favour of the experimental group.


Understanding the impact of commercial logging on composition and carbon storage of functionally different species is critical for sustainability of forest resources. This study assessed the floristic composition and carbon stocks of tree species of different conservation status along a post-logging chronosequence regime within the Bobiri Forest Reserve (BFR). Experimental plots were established in different post-logged sites within BFR, namely: 1-, 10-, 21-, 30-, 43- and 50 years post-logged sites (tagged as Y 1, Y 10, Y 21, Y 30, Y 43 , and Y 50 ). In addition, plots were established in an unlogged / undisturbed area which shows the characteristics of a strict nature reserve (tagged SNR) as control. Data was collected in 10 randomly selected temporary sampling plots (TSPs) in each site. The main sample plot (MSP) i.e. 50 m x 50 m (2500 m 2 ) was divided into four sub-plots (SP) of size 25 m x 25 m (625 m 2 ) and the sub-plots were further subdivided into sub-sub plots (SSP) of size 12.5 m x 12.5 m (156.25 m 2 ), to form a nested sample plot design. Tree species in the stands were identified and classified according to their conservation status/ star rating. The results of the study indicated that proportional abundance of species with different star ratings was significantly different with green and pink stars generally dominant across the stands. Carbon stock estimates increased from 193.5 ± 36.4 in the SNR to 293.3±45.1 in Y 50 , but was not significantly different. However, carbon storage among star categories was significant (p < 0.05) despite the low abundance of species in some of the categories. This phenomenon was due to the high proportions of carbon stocks in large and medium trees of species belonging to the green, pink, red and scarlet stars. The high carbon stocks of scarlet and red star species despite their low densities calls for management interventions to enhance their stocking levels within the reserve.


Given that the precautionary principle has never been defined in the EC Treaty, the EC jurisdictions have been playing a key role in determining the status as well as the scope of that principle. Although scholars have hitherto been paying heed to the case law on food safety, the literature has become a little thinner when one considers environmental case law. This article attempts to set the scene to explain how the precautionary principle can be invoked in different judiciary procedures at the EU level.


Abstract : The T47D human breast cancer cell line was grown in triplicate for 7 days in the presence or absence of the following hormonal treatments: estradiol (10-6-10-9M), tamoxifen (10-7M) or tamoxifen (10-7-10-9M) with 10-8M estradiol, calcitriol (10-8M), cortisone (10-7-10-9M), triiodothyronine(10-7-10-9M), progesterone (10-6-10-10M), testosterone(10-6-10-10M), retinoic acid (10-6-10-10M), or dexamethasone (10-710-9M) - No consistent dose-related effect on the growth was observed. The following human cell lines were screened in triplicate for the effect of calcitriol (10-8 M) on cell growth: T47D, CRL-1500, CRL-1897, HTB-20, HTB-23, HTB-24, HTB-26, HTB-27, HTB-30, HTB-122, HTB-126, HTB-131. Again, no consistent effect on cell growth was observed. The presence of the vitamin D receptor was verified in T47D, HTB-20, and CRLlSOO cells by PCR. To further investigate the action of more potent calcitriol analogues on cell growth, T47D, MCF-7, HTB-20, and HTB-131 cells were exposed to calcitriol, 22- oxacalcitriol, l6ene-calcitriol, and l6ene, 23 yne-calcitriol. Cellular proliferation was assessed in these experiments by 3H-thymidine incorporation and all treatments were done in triplicate or quadruplicate. No antiproliferative effect of calcitriol or its analogues over a 6 log concentration range was observed in any cell line tested. Calcitriol does not appear to be a modulator of cell growth in cultured human breast cancer cells and the use of calcitriol or its analogues does not appear to be a promising approach to therapy of breast cancer.


In October 2005 the U.S. Supreme Court accepted for review two cases challenging the application of the Clean Water Act to wetlands – Rapanos et al. v. United States (Dockett 04-1034) and Carabell et al. v. U.S. Army Corps of Engineers (Dockett 04-1384). Lower courts have ruled consistently against the defendants, who in both cases are Michigan developers seeking to build on designated wetlands. The fact that the sites are wetlands is not contested. The Court has consolidated these two cases for consideration and set oral arguments for 80 minutes on February 21, 2006.


Thank you for reading multidisciplinary treatment of soft tissue sarcomas. Maybe you have knowledge that, people have search numerous times for their chosen books like this multidisciplinary treatment of soft tissue sarcomas, but end up in infectious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they juggled with some infectious bugs inside their laptop.


Atomic layer chemical vapor deposition (ALCVD) of hafnium silicate films using a precursor combination of tetrakis (diethylamido) hafnium, Hf(N(C 2 H 5 ) 2 ) 4 , and tetra-n-butyl orthosilicate, Si(O n Bu) 4 was studied for high-dielectric gate oxides. The ALCVD temperature window in our study was 290-350°C with a growth rate of 1.1 A/cycle. We investigated the effect of deposition conditions, such as deposition temperature, pulse time of precursor, and purge injection, on the film growth. The saturated composition of the Hf/(Hf + Si) ratio was 0.37, and the impurity concentrations were less than 1 atom %. The dielectric constant (k) of the as-deposited hafnium silicate film increased upon annealing at 600°C, but decreased for annealing above 800°C. Hysteresis in the capacitance-voltage measurements was less than 0.3 V before and after annealing. The leakage current density of the as-deposited, 600°C, and 800°C annealed films was 5.3 X 10 - 2 , 2.2 X 10 - 2 , and 2.7 X 10 - 6 A/cm 2 , respectively, at a bias of -1 V.


This paper presents a hardware design for the Fractional Motion Estimation (FME) of the High Efficiency Video Coding (HEVC) standard. The solution designed in this work uses a scheme to reduce the number of accesses to the reference frames stored in the external memory in up to 49.22%. A strategy to reduce the computational effort is also used. This strategy consists in using only the four square-shaped Prediction Unit (PU) sizes rather than using all the 24 possible PU sizes. This approach reduces the total encoding time in about 59%, with a bit-rate increase of only 4% for the same image quality. The hardware design was described in VHDL and synthesized for FPGA and ASIC technologies. The synthesis results for TSMC 65nm standard cells demonstrate that the developed design is able to process UHD 2160p videos at 60 frames per second (fps), reducing the required hardware resources in about five times when compared with the main related work.


Environmental factors and spawning of the green sea urchin, Strongylocentrotus droebachiensis, were examined during 1983 and 1984 in the St. Lawrence Estuary. In both years, spawning occurred in June, which contrasts sharply with the February to early May spawnings reported for other locations. This difference does not appear to be related to temperature, but to the much delayed spring increase of phytoplankton in the Estuary. In both 1983 and 1984, sea urchin spawning coincided with the first marked and sustained increase in phytoplankton abundance (chlorophyll a levels of 1–2 mg∙m−3 for > 3 d) which took place about 2 wk before the main spring bloom; this first increase coincided with a sharp increase in salinity resulting from a decrease in freshwater runoff. Sea urchin spawned later in 1983 than in 1984. This difference did not appear to be related to either a critical temperature level or short-term temperature fluctuations; however, it did coincide with a greater freshwater runoff and a consequently...


We talk of the differences between the old Camus and the new Camus. Often such talk is equivalent to talk of the differences between Camus' old self and Camus' new self, between Camus' diachronous selves. In other contexts, contexts which I shall ignore, the old and the new Camus is something we can read, provide literary criticism of, ponder over. In these contexts it is to the literary works of the old and new Camus that we are referring. The same kind of ambiguity attaches to the expressions 'the early Beethoven' and 'the later Beethoven'.


(57) Abstract: Preferably online work, it is possible to automatically produce Namari畜 battery, a method of making a lead-acid battery, substantially lead electrode lattice shape produced in this case, paste the separation material on both sides provided subsequent Jo active substance directly to, storage stack, electrically connected, is inserted into the housing so as to produce a cell block, then in order to ripen the pasty active substance manufacturing method to be.


Contemporary trends in dosage form development for cardiovascular therapeutics are orientated towards the rationalization and individualization of drug administration with the achievement of good compliance. Therefore, the controlled release dosage forms occupy an important place in the therapy of cardiovascular diseases. In this paper, the survey of commercially available modified release preparations in our country is given, as well as the most commonly employed technologies for development of controlled release dosage forms. Another aspect that is often used in order to attain the flexibility of dosing is divisibility of the scored tablets. The main reasons for tablet divisibility as well as the potential problems and disadvantages are discussed with regards to the literature data and experimental results obtained in a separate study.


The generator exhaust waste heat and environmental pollution has more emphasized recently. Out of the total heat supplied to the engine in form of fuel, approximately 30 to 40% is converted into useful mechanical work. In this present work thermal energy storage tank is integrated with an I.C. engine setup to extract heat from the exhaust gas using two types of phase change materials (Paraffin wax type-2 And Stearic acid).The performance parameters pertaining to the storage tank such as amount of charging time, discharging time, water flow rate, heat recovered, heat lost, and % of energy saved are evaluated in this work.


Sir, We thank Perez et al. [1] for reporting an interesting case of cast nephropathy (CN) in a patient with lymphoplasmacytic lymphoma (LPL). The authors reported the above finding as the first report of CN-associated LPL with bone marrow (BM) and lymph node involvement. WHO (2008) had defined LPL as B-cell neoplasm composed of small lymphocytes, plasmacytoid lymphocytes and plasma cells, usually involving the BM and sometimes the lymph nodes and spleen, which does not fulfil the criteria for any other B-cell neoplasm with plasmacytic differentiation [2]. Waldenström's macroglobulinaemia (WM) (WHO 2008) is defined as the presence of an IgM monoclonal gammopathy of any concentration associated with BM involvement by LPL [2]. The diagnosis of the LPL reported by Perez et al. is not clear, as it qualifies for WM rather than LPL (IgM 17.7 g/L, IgG values not mentioned and BM infiltration present). So the reported case is not the first case but at least the third case of CN with WM. The author has defined WG as LPL with BM involvement and monoclonal gammopathy but with normal lymph node architecture stating WHO 2008 as reference. However, the WHO 2008 definition of WM does not comment on lymph node architecture. Taken together, the diagnosis of LPL (and not WM) in the given case is not clear. We would like to respectfully point out that Bashir [3] had earlier reported a case of WM and dialysis-dependent renal


We have previously identified a GAAAATATGATA binding site (pros) of a transcription factor involved in prostatic and androgen‐dependent gene regulation. We now purified the potential factors interacting with the pros and characterized their co‐operation with the androgen receptor (AR).


1Department of Pediatric Immunology, University Medical Center Utrecht, Utrecht, The Netherlands. 2Department of Infectious Diseases and Immunology, Division of Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. 3Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands. 4Section of Molecular Medicine, Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612.


We take great pleasure in being able to state that there is now a successful means of eliminating Sugar Pine brown stain. This has been more than 30 years in coming after considerable effort by many people. Research was done on a national level by the U. S. Forest Products Laboratory, on a regional level by the Western Pine Association Laboratory with cooperating mills and by many others. Some of you are partially familiar with the final phases of the work through your assistance in the testing program. HISTORY


Focal brain ischemia induced in rats by occlusion of an intracranial artery is a widely used paradigm of human brain infarct. Details of the structural changes that develop in either the human or the rat brain at various times after occlusion of an intracranial artery are incom-pletely characterized We studied, in 48 adult Wistar rats, structural alterations involving the cerebral hemisphere ipsilateral to an arterial occlusion; at intervals ranging from 30 min to 7 days. Microscopic changes developed over time in separate areas of the corresponding cerebral hemisphere in a predictable pattern; appearing as small lesions in the preoptic area (30 min-utes), enlarging to involve the striatum, and finally involving the cerebral cortex. Two types of neuronal responses were noted according to the time elapsedR acute changes (up to 6 hours) included scalloping, shrinkage, and swelling, whereas delayed changes (eosinophilia and karyolysis) appeared later ( . 12 hours). Three types of astrocytic responses were noted. 1) neurons minimally injured were prominent the cerebral a minimal


When facing challenging circumstances in college athletics, Bridget Belgiovine, B.S., M.Ed., knows better than to try to go it alone. Instead, she knows "it takes a team" to ensure the most effective management of the most significant challenges facing college athletics, she said.


We report a clustering of public human protein kinase structures based on the conformations of two structural elements, the activation segment and the C‐helix, revealing three discrete clusters. One cluster includes kinases in catalytically active conformations. Each of the other clusters contains a distinct inactive conformation. Typically, kinases adopt at most one of the inactive conformations in available X‐ray structures, implying that one of the conformations is preferred for many kinases. The classification is consistent with selectivity profiles of several well‐characterized kinase inhibitors. We show further that inhibitor selectivity profiles guide kinase classification. For example, selective inhibition of lck among src‐family kinases by imatinib (Gleevec) suggests that the relative stabilities of inactive conformations of lck are different from other src‐family kinases. We report the X‐ray structure of the lck/imatinib complex, confirming that the conformation adopted by lck is distinct from other structurally‐characterized src‐family kinases and instead resembles kinases abl1 and kit in complex with imatinib. Our classification creates new paths for designing small‐molecule inhibitors. Proteins 2008. © 2007 Wiley‐Liss, Inc.


The present invention at least one electrical component is dielectric having a substrate, and at least one electrical component surrounding conducting a plurality of separate electrical disposed in a pattern on the substrate securing unit a and the inner surface the outer surface disposed above the material layer and the shielding portion and having an electrically conductive layer on at least one of the inner and outer surfaces; All openings comprises a plurality of apertures formed in the shield so as to correspond to the pattern of the electrically conductive fastening unit and the opening of the at least one dielectric material layer shield in the contact region of the opening has a contact area and the conductive layer is a contact area combined with the electrically conductive fastening units, and possible bias so required to allow the retaining and; The conductive layer of the shield at the contact region is directed to the EMI shield are electrically and electrically conductive fastening unit contact.


During the last few years, interest in overall economic growth as the best measure and object of development has increasingly given way to a preoccupation with the distribution of income and thus with how the benefits of economic growth are shared. Within this general concern is a specific preoccupation with the poorest families in less-developed countries, who may remain in dire poverty despite significant increases in income per head or other measures of development.