Stunting is a growth disorder in children caused by malnutrition for a long time. The child's condition becomes shorter than normal children his age and has a delay in thinking. The incidence of stunting in Indonesia is quite high sostunting is becoming a priority health problem now. An effective strategy is needed to control stunting in Indonesia. The aim of this review was to explore the stunting management strategies to potentially implement in Indonesia.A literature review design was used to explore the stunting management strategies. Literature study of 15 articles retrieved from the journal database of Science Direct, Proquest, Scopus, and EBSCO in the last 5 years using keywords stunting, management, rural areas, and community based. Data were analyzed in tables consist of title, author, year, sample, methodology, and result. Control and preventionstunting could done through integrated nutrition interventions.Strategy Specific nutritional interventions such as providing supplementation and supplementary food plus nutritional interventions including non-health interventions, improving the family's economy, access and utilization of clean water, sanitation (especially latrines and safe septic tanks), which are urgently needed to support personal hygiene behavior and the environment . Interventions can use mother's counseling and support methods regularly by health workers by involving health cadres.Specific and sensitive intervention strategies are effective strategies within stunting control and prevention. Monitoring and evaluation of nutritional knowledge, attitudes and practices coupled with an assessment of the nutritional status and morbidity of mothers and children is also very necessary in controlling and preventing stunting in Indonesia


This paper utilizes the methods of literature,data analysis method,visit the teammember contrast with the referee,interviews with experts on the third Straits "Forum:Maritial Arts Competition across the Taiwan Strait",and puts forward relevant suggestions,development of the host condition of Maritial Arts Competition,for the improvement of the people on both sides of cultural exchange,and at the same time,promote technology from each other,the emotion blends the interaction of martial arts,reference and harmonious culture blend on both sides can play a lot of thrusting action.


Objectives: Serum levels of carcinoembryonic antigen and cancer antigen 15-3 tumor markers are used for breast cancer prognosis. This study developed a breast cancer prognosis prediction model.Methods: We retrospectively analyzed data of 639 patients diagnosed between January 2012 and December 2019. We selected 20 independent variables with carcinoembryonic antigen and cancer antigen 15-3 serum levels and employed four machine-learning algorithms for the model: artificial neural network, random forest, support vector machine, and logistic regression.Results: Significant differences in carcinoembryonic antigen and cancer antigen 15-3 serum levels, age, history of other diseases excluding hypertension and diabetes mellitus, chemotherapy, and drug therapy were noted between control (n = 576) and case groups (n = 63). The sensitivity and specificity of the artificial neural network model for prognosis prediction were 26.7% and 92.6%, respectively.Conclusions: Carcinoembryonic antigen and cancer antigen 15-3 serum levels were the most significant variables for developing a breast cancer prognosis prediction model using the Shapley additive explanations model. The proposed machine-learning model and tumor marker serum levels may be useful for breast cancer prognosis.


A growing number of cities around the world have been chasing the Sustainable Development Model, balancing between economic health, environment resilience and social equity in an overall transparent governance. Given the demographic trend of cities, welcoming an increasing share of the world's population, urban planners and government officials are challenged by a growing Urban Density. With a significant population increase pace, Portland's leadership in Sustainability that the largest city of Oregon is claiming could be jeopardized by the effects of Urban Density. What should Portland's urban planners and policies makers do to overtake this challenging trend and remain in a leading position in Sustainability? Various solutions exist in different sectors. Using an Analytic Hierarchy Process (AHP) method, this paper starts by developing a multi-perspective, multi-criteria model that will integrate Portland's specificities for a sustainable overtake of Urban Density. Then, by integrating to this model the proper expertise, the outputs of this model result in a ranked proposal of solutions which aim to give Portland's city planners and leaders an orientation as of which path to consider for preserving Sustainability in an increase urban density context based on both a qualitative input and a quantitative computation of expertise. While the experts' rankings reached a significantly low disagreement rate, B Corp incentive program was the preferred solution for all the panel. Therefore, tackling the Urban Density issue from the economic side was our recommendation.


A review is given of the recent progress and trends in lens design and also considers the possible developments for the future.


With the growing competition and complexity of marketing information,interpersonal communication is becoming increasingly important to marketers and consumers (mavens) who can act as disseminators of marketing communications and play an important role. Previous research, which has found that mavens are more likely to be female, has ignored the way in which these consumer communicators make decisions and process information. As male product markets grow and gender roles in shopping become blurred, identifying male mavens could be a useful promotional tool. Sixty male and 78 female market mavens were identified from a survey of 455 German consumers, which differed only marginally in terms of age and education. The prime decision-making traits of male mavens differed from females and were related to brand consciousness, shopping avoidance/satisficing, impulsiveness, speedy fashion seeking, perfectionism, price–value consciousness, confused by overchoice and quality brand loyal. Implications and recommendations for marketers targeting male product markets in Germany are discussed.


Objective To explore the dead reasons and related factors of acute leakemia(AL)in children.Methods The clinical data of 42 dead cases of children with AL,who were admitted to Guangzhou Children's Hospital between Jan.1999 and Mar.2007 were reviewed.Nineteen cases were boys,23 cases were girls;the aging from 4 months to 12 years old and 5 months.Of 42 children,21 cases were acute lymphoblastic leukemia(ALL),18 cases were acute myeloid leukemia(AML),3 cases were unclassified AL.Results Ten out of 12 early-dead cases died of bleeding.Among 30 cases who received chemotherapy,4 cases died of bleeding,others of myelosuppression combined with infection,14 of whom died from sepsis,3 cases with fungal infection,1 case with virus infection,4 cases with unknown pathogens.Sixteen children relapsed among those who got remission,half of them relapsed within 1 year since diagnosed.Treatment-related mortality(TRM)was 90%(27 out of 30 cases).The main causes of TRM were infection and hemorrhage.Hyperleukocytosis and bleeding were 2 risk factors related to early death in new-diagnosed children.Conclusions More emphasizes should be put on bleeding tendency during early treatment in children with AL and treatment of infection complications during induction chemotherapy to reduce TRM.


Purpose
Delays in construction projects can be very expensive due to their adverse effects on project cost and profit margin. To overcome this problem, clients in the construction industry sometimes use schedule incentive/disincentive (I/D) contracting strategy. However, previous studies have shown that inadequate understanding and wrong implementation of schedule I/D provisions could result in unintended results. Moreover, the use of the I/D contracting method is in its initial stages in many countries such as India. The purpose of this paper is to identify various factors that are essential for schedule I/D success in construction projects.

Design/methodology/approach
A questionnaire survey was conducted among experienced professionals (clients, contractors and consultants) from across the Indian construction industry.

Findings
Top success factors related to clients in the descending order of their importance are: realistic targets; detailed guidelines for I/D implementation; close coordination with other stakeholders; correct estimation of I/D duration and amount; and imposing disincentives after due consideration. Meanwhile, factors related to contractor organisations are: continuous monitoring and control; thorough understanding of schedule I/D targets; specific considerations in appointing senior project personnel; effective communication; and proper labour management.

Research limitations/implications
This empirical research was conducted in the Indian construction industry. Similar studies from developed construction markets may provide more insights into the successful use of schedule I/D provisions in construction projects.

Practical implications
The uptake of these recommendations is likely to increase the success of schedule I/D provisions in construction projects, especially in developing countries where the use of I/D contracting strategy is not very popular.

Originality/value
This research highlights the specific roles of both clients and contractors in the success of schedule I/D projects in developing countries such as India.


Abstract The pace of education technology innovation outpaces many professors' abilities to thoughtfully integrate new tools in their teaching practice. This poses challenges for higher education faculty as well as those responsible for planning professional development in higher education. This article explores recent trends in education technology and the capabilities that new pedagogical tools make possible. It also introduces readers to three foundational educational technology theories: Rogers' diffusion model, Davis's technology acceptance model and Mishra & Koehler's technological, pedagogical and content knowledge model. Each theory holds important implications for those interested in helping higher education faculty members to make the most of emerging classroom technologies. Higher education leadership can help their faculties make the most of education technology tools by including the implications of these theories in their professional development designs.


Abstract This paper reports on the electrowetting behavior on three micro/nanostructured ZnO (zinc oxide) layers with different roughnesses. ZnO nanorods with diameters of 100 nm and heights of 1 um (sample A), 3 μm (sample B), and micro flower-like layer with a diameter of 5 μm (sample C) were fabricated on the ITO glass substrates. This was followed by deposition of Teflon to achieve superhydrophobic property on the prepared surfaces. On these three Teflon modified ZnO layers, reversible electrowetting phenomenon was observed on the sample B with applied voltages of less than 40 V, and also on the sample A with a large range of voltage in air environment, but irreversible electrowetting behavior was observed on sample C. The wettability change and reversibility have been analyzed, and it is shown that the differences in the structures of the ZnO layers play a crucial role in the distinct electrowetting performances.


Abstract Background Negative symptoms represent a core feature of schizophrenia. They have been associated to poor functional outcome, worse quality of life and poor response to pharmacological treatment. Several factor analytic studies have reported that negative symptoms can be divided into two domains referred to as Avolition-apathy which includes Avolition, Anhedonia and Asociality and the Expressive deficit domain, which includes Alogia and Blunted affect. Avolition-apathy has been associated to a dysfunction of brain circuits involved in motivation, in particular to those related to the ability to anticipate pleasure and learn from rewards. It is highly controversial whether Avolition-apathy and all subcomponent symptoms share the same neurobiological underpinnings. Our study, using brain electrical microstates (MS) which reflect global, subsecond patterns of functional connectivity, had two primary aims: 1) to identify differences between healthy controls (HC) and clinically stable people with schizophrenia (SCZ) in brain electrical microstate parameters and 2) to investigate the associations of the microstate parameters with the Avolition-apathy domain and its subcomponent symptoms. Methods We analyzed multichannel resting EEGs in 142 SCZ and in 64 HC, recruited within the add-on EEG study of the Italian Network for Research on Psychoses. The microstate analysis was performed using an in-house plugin for Brain Vision Analyzer. Based on the microstate map templates from a large normative study, each moment of the ongoing EEGs was assigned to one of four microstates (MS) classes (MS-A, MS-B, MS-C, MS-D). Microstates were then quantified in terms of relative time contribution, duration and occurrence. Negative symptoms were assessed using the Brief Negative Symptoms Scale (BNSS): Avolition-apathy was obteined by summing the scores on the subscales Anhedonia (consummatory and anticipatory anhedonia), Avolition and Asociality; Expressive deficit was computed by summing the scores on the subscales Blunted Affect and Alogia. Analysis of variance (ANOVA) was used to test group differences on MS parameters. Pearson's r coefficients were computed to investigate the correlations of MS parameters with the negative symptom domains and subcomponent symptoms. Results There was no significant group difference in sex (p=0.073) and age (p=0.547) between SCZ and HC. SCZ, in comparison to HC, showed increased contribution (p=0.009) and duration (p=0.016) of MS-C. As regard to negative symptoms, the total score of the BNSS was positively correlated with the contribution of MS-A (r= 0.19, p<0.03). Avolition-apathy domain (r=0.22, p<0.01), anticipatory anhedonia (r=0.20, p=0.02), avolition (r=0.20, p=0.02) and asociality (r=0.25, p=0.003), but not consummatory anhedonia (r=0.13, p=0.13), were positively correlated with the contribution of MS-A. There was no correlation between Expressive deficit and MS-A parameters. Discussion Our findings, in line with previous studies, showed an increased contribution of MS-C in SCZ. MS-C was not associated with clinical features, thus probably representing a trait marker of the disease. In addition, our results support different neurophysiological correlates of the two negative symptom domains and suggest that only anticipatory anhedonia, but not consummatory anhedonia, might be linked to the Avolition-apathy domain. These findings are in line with studies reporting an intact ability to experience in the moment pleasure and an impairment in pleasure anticipation (anticipatory anhedonia) in people with schizophrenia.


Objective: To study the clinical value serial section of fetal cardiac ultrasound examination in the diagnosis of fetal congenital heart disease.Method: High-risk pregnant women of 742 cases used serial section of fetal echocardiography examination: four-chamber view,left ventricular outflow tract section,right ventricular outflow tract section,section three vessels,three vessels tracheal section,catheter bow section,the aortic arch section,the long axis of the aorta section,long axis view of the superior vena cava.Result: 742 cases of pregnant women at high risk of fetal congenital heart disease,26 cases were checked out,there were still three cases of prenatal misdiagnosis and 2 cases of misdiagnosis,diagnosis rate was 83.87%,misdiagnosis rate was 16.13%.Conclusion: Sequences of fetal cardiac ultrasound examination of fetal congenital heart disease section has a higher diagnosis rate,can reduce the misdiagnosis rate


How long-term inmates perform any number of identities across the span of a prison career is a question that must be negotiated by each individual as he struggles with the perils of life behind bars. With a phenomenological and grounded theory approach, this study sought to demonstrate how inmates in a men's maximum security prison enact their evolving identities across the span of their incarceration and what challenges they experience in doing so. Problematic integration further clarifies these challenges. Namely, negotiating multiple divergent identities results in significant uncertainties, ambivalence, and divergence as inmates struggle with how best to communicate.


The purpose of this study is to identify core Environmental Information Disclosure (EID) contents and to evaluate the current level of EID proactiveness of the hotel companies on the Global Reporting Initiative (GRI) database. We confirmed 38 reports as a sample from 2008 to 2014. Utilising content analysis and a case study approach, we comprehensively investigated the quality and extent of what is being reported and evaluated in respect to each hotel's EID proactiveness. Six core EID categories which had received significant attention from the hotels were identified, and we found the sampled hotels emphasised cost reduction activities of their operations in their EID. EID proactiveness was addressed and there was significant difference between the EID proactiveness groups (top, middle, bottom) in terms of property, quality and quantity. This study provides an overview of the current level of EID proactiveness of the hotels in the GRI database and also provides a measure for EID proactiveness for the hotel sector.


This study aims to develop a basketball game model for elementary schools. The model that was made beforehand was validated by 3 experts, 1 sports academic expert, 1 expert trainer and 1 referee expert. The small group test involved 6 elementary school children and the trial group involved 25 elementary school children. The basketball game model for elementary schools has been validated and results from expert validation that each model is valid and can be used as a basket play model for children, with a validity percentage of 76% -100%. The results of a small group test of 6 elementary school children showed that the basketball game model at the elementary school has met the reader properly or is valid. The percentage of validity of the questionnaire that was distributed to the sample showed that 91% -100% of them agreed with the ball game for schoolchildren. The percentage of validity from the questionnaire that was distributed to the sample shows that 87% - 97% of those who approve the game meet the criteria.


In allusion to the issue of controlling efficaciously sub-micron particles emissions in coal combustion, a new measure that can cooperate with removing manner of Chinese present power station is put forward and its core idea is that through spraying a high stickiness agglomerating solutions into sub-micron particles in gas are being agglomerated to bigger particles and are removed by removing devices. In order to prove the validity, a minitype agglomeration experimental stove that simulated gas flow is set up and the model about the agglomeration of sub-micron particles is set up. The model result showed that gas flux, soot concentration, solution flux and concentration are the important factors impacting on the agglomeration of sub-micron particles; on the condition of ensuring the gas temperature reducing less than 10℃, that solution concentration and flux are suitably added is to reach 70% agglomeration rate, which proves the way validity and then provides references for farther tests.


This paper presents an easy and direct algorithm to solve the issue of load balancing in providing Data as a Service (DaaS) in the Cloud. The algorithm is based on some earlier approach for efficient dual direction data downloading. Our contribution is in solving the issue of the high storage demand when storing replicated data in multiple Cloud nodes. Rather than storing full replicas, our approach devises a model to store partial replicas of the data on multiple distributed Cloud servers. Moreover, we provide a direct method to download this data from multiple Cloud servers by coordinating the download process among the different nodes and different parts of the replicas on the Cloud. We implemented and evaluated our algorithm on the top of the CloudSim toolkit.


This study examines the effect of temperature and moisture on the flexural properties of quasi-isotropic Kevlar 49 fabric/epoxy composite laminates. Part I of this study treated the [0/90] filament orientation. Additional variables evaluated in Part II which were not studied in Part I include the effects of voids, long term moisture exposure, freeze-thaw thermocycling, the reversibility of moisture exposure and laminate unload ing behavior. Results indicate that the [±45,0/90] laminates exhibit a de pendence on temperature and moisture similar to the [0/90] laminates, but that the quasi-isotropic orientation is somewhat less sensitive to moisture at 21 and 150°C. Strength losses in the quasi-isotropic laminates can nevertheless be substantial. At 150°C and near saturation moisture content, the strength is 55-60 percent lower and the stiffness 40 percent lower than 21°C dry values. Voids, freeze-thaw cycling of specimens with voids and moisture, and long term moisture exposure all degrade laminate strength. Specimens subjected to long term moisture exposure followed by drying displayed stiffness values equivalent to as-fabricated results, but did not totally recover in strength properties. Flexural strengths of the dried specimens were similar to those of fully moisture saturated material at 21°C (15-20 percent loss from dry values). The lack of 100 percent re covery in strength indicates that moisture effects are not totally reversible. Microscopic examination of failed specimens showed no filament buckling at 21°C. Failures are characterized by a tensile delamination mode which may be induced by edge effects produced by the off-axis filament plies.


This research project was performed to study the performance of carbon nanotubes (CNT) grown on granular activated carbon (GAC) as an adsorbent for removal of heavy metal (mercury) from aqueous solution. The effect of pH, agitation speed, contact time and CNT dosage was studied for optimal adsorption of mercury in the aqueous solution. Design Expert software was used to determine the number of runs and its variations, which are 18 runs. It was found that the optimal condition for mercury (II) ions adsorption occurred at adsorbent dosage of 5 mg, pH value of 5, contact time of 120 minutes and agitation speed of 150 rpm with a value of 0.031 mg/L residual amount.


Abstract Background Multisystem inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection shares features with other inflammatory states, notably Kawasaki Disease. The rickettsial infection murine typhus is also in the differential for MIS-C in endemic areas. As the therapeutic approaches differ, it is essential to distinguish these disorders soon after presentation, well before confirmatory serologic testing results. Our objective was to develop an algorithm to accurately predict MIS-C versus typhus. Methods Retrospective review extracted demographic, clinical, and laboratory features available within 6 hours of presentation for 133 MIS-C and 87 typhus patients. 33 features were broken into 44 inputs and passed through an attention module to compute importance. Inputs were then entered into machine learning algorithms as MIS-C or typhus. Patients were divided into training and test cohorts respecting proportions in the dataset. An equation was built to calculate the "MET" (MIS-C versus endemic typhus) score. Results MIS-C patients were younger (8.4 v 11.2 years, p< 0.0001) and the majority (71%) presented on day 4-6 of fever; most typhus patients (84%) presented with ≥6 days (mean 4.9 v 7.3 days, p< 0.0001). Typhus patients were more likely to have rash (86% v 51%, p< 0.0001) and MIS-C patients red eyes (71% v 36%, p< 0.0001), other features were similar. MIS-C patients had higher C-reactive protein levels (17.7 v 9.8 mg/dL), procalcitonin (14.0 v 0.48 ng/mL), fibrinogen (558 v 394 mg/dL) and neutrophil-to-lymphocyte ratio (12 v 3.5), all p< 0.0001, other parameters were similar. MIS-C patients were also more likely to have elevated troponin (0.48 v 0.01 ng/mL, p< 0.0001) and require intensive care (66% v 6%, p< 0.0001). A long short term memory network outperformed 6 other models (99% accuracy using all 33 elements). The MET score predicted MIS-C versus typhus with 90% accuracy using only 10 features (sensitivity 90%, specificity 90%). Conclusion The clinical and laboratory similarities between typhus and MIS-C present challenges, but they can be reliably distinguished using artificial intelligence with as little as 10 features. Our ongoing interprofessional collaboration aims to make the MET score readily available to clinicians for use in patient encounters. Disclosures Flor M. Munoz, MD, MSc, Gilead: Grant/Research Support|Moderna: DSMB|Pfizer: DSMB Tiphanie Vogel, MD, PhD, Moderna: Advisor/Consultant|Novartis: Advisor/Consultant|Pfizer: Advisor/Consultant.


Many twentieth-century accounts of history have used geological tropes to describe the phenomenon of historical knowledge, and such terms have been of particular importance in the phenomenological tradition. In Heidegger's references in Being and Time to the "soil of history," Husserl's account in his later work of "sedimentation" in the lifeworld, and the reformulation of this notion in the phenomenology of Merleau-Ponty, geological tropes are used to illustrate important insights into the relation between contingency, a priority and historicity. This paper seeks to contribute to an understanding of history understood phenomenologically as historicity through an analysis of these geological tropes. Our findings can be summarized as follows: such geological tropes help the phenomenologist to describe the way in which history is always determined within a complex interplay between only temporarily fixed determining structures such as riverbanks, insoluble sediment, soil, etc. and free-flowing praxis, a situation in which historical events are at once determinant of and themselves determined by human activity. Paradoxically, the constant and "grounding" element in such conceptions of history is not the sediment and hard rock of historical fact, but the the constant change and variability-despite the sense-giving continuity of human experience structured by historicity. We begin with a brief overview of the landscape on the philosophy of history in which these views arose, and then continue to an analysis of the tropes themselves.


Researchers have examined decision-making related to participating in sexual activity and resisting sexual advances. However, ambivalence about sexual participation has received little research attention. A sample of 194 US college students (96 men, 98 women) completed surveys designed to examine uncertainty about engaging in sexual activity with a dating partner, the factors that influence eventual decisions regarding participation, and the perceived emotional and relational consequences of these decisions. The majority of students (81%) reported at least one episode of ambivalence in the recent past. In over half the cases (53%), respondents reported eventually rejecting their partners' sexual invitations, usually because of relationship or intimacy concerns. Those who eventually accepted their partner's sexual invitation typically attributed their decision to becoming more aroused or wanting to promote intimacy in their relationship. Overall, ambivalence about participating in sexual activity seems to have few deleterious consequences for individuals and their relationships. However, the findings emphasize the need to promote clearer communication about sexual intentions and desires between dating couples.


To avoid the instability of an optical coefficient measurement using sliced tissue preparation, an attenuation coefficient measurement by puncturing an optical fiber in bulk tissue have been reported. We proposed a modified puncturing method to obtain an absorption coefficient and scattering coefficient by increasing optical information. We used the light intensity measurement through a single high-NA fiber puncturing into an optically thick bulk tissue varying detection parameters, the depth and field of view (FOV), at the tip. The light intensity measurement and ray trace calculation using the Monte Carlo method (inverse or normal) were employed. We constructed the measurement system which can change the FOV at the fiber tip inside the bulk tissue using the variable aperture outside the bulk tissue. A 200 μmΦ NA:0.5 fiber installed in a 21G needle was punctured down to surface of the bulk tissue to measure light intensity in the bulk tissue. Using homogeneous optical model solution, the accuracy about attenuation coefficients of the constructed experimental system was confirmed. The error in the attenuation coefficient was up to 1.4%. We demonstrated the optical coefficient measurement of porcine myocardium using the proposed method. To fit dependence of the measured attenuation coefficients on FOV, we decided that the absorption coefficient, the scattering coefficient, and anisotropic parameter were 0.2 mm-1, 10 mm-1, and 0.96, respectively. We proposed modified puncturing optical coefficient measurement varying depth and FOV. We demonstrated its usefulness on myocardium.


Introduction: Injury to the lateral ligament complex of the ankle manifesting as ankle sprains are the most frequently incurred musculoskeletal injury [1]. Up to 70% of those who sustain a single lateral ankle sprain report residual symptoms, including recurrent bouts of instability, additional ankle sprains and reduced functional capacity [2]. These negative antecedents form the primary characteristics of chronic ankle instability (CAI), which although often considered an innocuous injury, has been associated with an increased risk of developing co-morbidities such as post-traumatic ankle osteoarthritis. CAI has been linked to many mechanical insufficiencies including reductions in posterior talar glide and dorsiflexion range of motion (DF-ROM). Joint mobilisation techniques that target the posterior glide of the talus are purported to increase DF-ROM through the restoration of arthrokinematic movements that occur between the talus and ankle mortise. Although joint mobilisations are informed by a conceptual framework of clinical reasoning, there is a lack of consensus within the literature regarding their effectiveness as a clinical technique. Further, there is a paucity of methodologically rigorous research into the interaction between treatment dose and ROM improvements [3]. The purpose of this study was to examine the effect of different treatment durations of a grade IV anteroposterior talocrural joint mobilisation on weight-bearing DF-ROM (WB DF-ROM) during a 2-week treatment intervention.

Methods: Forty-eight female team sports athletes (age = 22.8 ±4.8 years) participated in the study. All participants presented with a history of ankle instability which was confirmed using the Cumberland Ankle Instability Tool (CAIT), where a score of less than 24 was used to indicate the presence of the condition. Participants were randomly assigned to one of three treatment conditions (30 seconds, 60 seconds, or 120 seconds), and received six treatments equally spaced over a 2-week period. WB DF-ROM was measured prior to and immediately following each treatment session using the weight bearing lunge test and knee-to-wall principle. Two-way mixed model ANOVA was used to test for differences in WB DF-ROM between groups. Simple main effects were calculated to determine the difference between treatment groups following each treatment session. Effect size statistics were calculated using Hedge's g.

Results: Statistically significant interaction effects between the treatment group and treatment session for WB DF-ROM (F (17.042, 306.754) = 6.954, p ≤ 0.001, partial η2 = .279, έ = 0.682) were evidenced (Table 1). A significantly greater improvement in WB DF-ROM was observed in the 120 second treatment group compared to the 30 second group following treatment sessions 1, 2 and 3 (p ≤ 0.001). Longer treatment durations were seen to produce significantly greater improvements in WB DF-ROM than lesser durations following treatment session 2 and 3 (p ≤ 0.001). No significant differences were observed between treatment groups following treatment session 4, 5 or 6 (p ≥ 0.05). Effect size statistics showed that there was a 'very large' (g ≥ 1.2) effect for the 60 second treatment group following treatment session 1, and for the 30 second treatment group following treatment session 2. All other effect sizes were 'huge' (g ≥ 2.0).

Conclusions: These results indicate that an anteroposterior talar joint mobilisation is able to improve measures of WB DF-ROM in females with CAI regardless of treatment duration, whilst increases in treatment durations confer greater improvements during the first 3 application sessions. Consequently, longer treatment durations should be utilised early on in the treatment process to address ankle range of motion deficits.

References:
1. Fong DT, Hong Y, Chan LK, Yung PS, Chan KM. A systematic review on ankle injury and ankle sprain in sports. Sports Med 2007, 37:73–94.
2. Wikstrom EA, Tillman MD, Chmielewski TL, Cauraugh JH, Naugle KE, Borsa PA. Self-assessed disability and functional performance in individuals with or without ankle instability: a case controlled study. J Orthop Sport Phys Ther 2009, 39:458-67.
3. Holland CJ, Campbell K, Hutt K. Increased treatment durations lead to greater imporvements in non-weight bearing dorsiflexion range of motion for asymptomatic individuals immediately following an anteroposterior grade IV mobilisation of the talus. Man Ther 2015, 20(4):598-602.


A molecular study of five strains of the eastern equine encephalitis virus (EEEV) was conducted by sequencing of products generated using the reverse transcriptase assay, coupled to the polymerase chain reaction (RT-PCR). Sequences of approximately 500 pair of bases from the non-translated 3' region of the genome were compared with homologous sequences of the South American (SA) and North American (NA) variants of the EEEV complex. The EE VE02 EL PAO strain, used to develop an inactivated oil vaccine had most resemblance with the EE VE76 EL DELIRIO strain, followed by the EE VE75 CATATUMBO, the EE VE96 MLLANO and the EE VE84 TUCACAS strains, respectively. The alignment of sequences among typical strains revealed differences of 2.82 and 8.48%, respectively, while the EE VE02 EL PAO strain differed in 8.86% from the Peru strain (EE PE-0.0155, from lineage III) and in 38.08% from the NA strain (EE-PE-6, from lineage I, used in commercial vaccines). The results of the present investigation indicate that the autochthonous strains have more similarly with the SA strain than with the NA strain. Four major lineages (I-IV) in the EEEV complex have been identified. The


The property of melting is used to provide a cheap, quick and reasonably accurate determination of thermal conductivity, needing very little preparation or apparatus. The method is free from the need for constant ambient conditions, and can accommodate specimens of moderate flatness and any reasonabIe size and shape.


The US NCRP-report 46 "Alpha-Emitting Particles in Lungs" [4] deals with the effect of plutonium ce-particles in the lung and its dependence on the size of the 239puO2 particles. If a given activity is uniformly dispersed, then a maximum number of cells is traversed by c~-particles. The probability for multiple traversals of one cell is small. If, on the other hand, the activity occurs in a39puO2-particles, then cells close to these particles will be subject to multiple traversals; the total number of cells at risk will be accordingly reduced. In addition malignant transformations produced by the ceparticles are less likely to express themselves. The reason is that multiply traversed cells will be very unlikely to retain their proliferative capacity. The report deals with these matters in detail and arrives at the conclusion that a given activity will be less effective when it occurs in 239pUO2 particles. Computed numbers of cells traversed by one or more ce-particles are presented; these data are essential to the argumentation. Since the basis of the computations is given only in brief form in the appendix of the report, it is felt that a detailed derivation will be useful.


To the Editor. —Two articles 1,2 concerning early discharge of newborns came to contradictory conclusions concerning whether early discharge is associated with increased risk of rehospitalization, as discussed in the accompanying Commentary. 3 This prompted us to relate the experience of MedSpan, a Connecticut-based, provider-sponsored managed care organization, with a voluntary early discharge program offered to our policyholders and the effect of Connecticut state legislation. Mothers and their healthy infants who met physician-established criteria and volunteered to be discharged from the hospital within 30 hours of normal vaginal delivery were offered 2 skilled nursing visits at home, 16 hours of nanny care, and 1 extra pediatric office visit. We analyzed utilization of services among 77 consecutive mothers who used the program during a 19-month period beginning January 1, 1996 (unpublished data, August 1997). We found that 1 mother did not use any nursing visits, 5 used 1 visit, 70 used 2 visits, and 1


Based on the redox behavior of tetrathiafulvalene and unique platform of calixarene,two ether-linked tetrathiafulvalene-calixarene derivatives(4a and 4b) were designed and synthesized,which were characterized by 1H NMR,13C NMR,FAB-MS,IR and elemental analysis.Their electrochemical properties were investigated by cyclic voltammetry method and two quasi-reversible waves with redox potentials were observed.Meanwhile,the UV-Vis spectra was used to exploit the intermolecular electron transfer between the target compound(4a and 4b) and tetrachloro-1,4-benzoquinone(Q) regulated by metal ions(Na+,K+ and Ba2+).The results show that the K+ may effectively promote the electron transfer between 4b and Q system,which will be helpful to develop TTF-based supramolecular systems for intermolecular electron transfer.


e20001 Background: Multiple Myeloma (MM) is a neoplasm of the post-germinal center, terminally differentiated B-cells. MM accounts for 1% of all types of cancer and 10% for all hematologic malignancies. Chronic hepatitis C virus (HCV) is an infection that affects over 71 million patients worldwide. Cytotoxic agents and immunosuppressive therapy as steroids are the main line of therapy in lymphoid malignancies, but these drugs may exacerbate chronic viral hepatitis and cause uncontrolled replication of hepatitis viruses. The impact of HCV infection on MM patients remains unclear. Objective: To assess the impact of HCV infection on the prognosis and management of MM patients. Methods: A 10-year retrospective study of MM patients was conducted at Cairo University Clinical Oncology Department from January 2009 to April 2019. Results: During this time, 150 patients were diagnosed with MM, 109 (72.7%) were HCV negative, 24 (16%) were HCV positive, and 17 (11.3%) with unknown HCV status. The median age was 51 and 54 years for HCV negative and positive groups respectively, with a statistically insignificant difference (p-value > 0.2). In the multivariate analysis, HCV infection was not an independent factor related to overall survival (OS), however age, creatinine and hemoglobin levels correlated significantly with OS (p < 0.009, 0.008, 0.031 respectively). The median OS for the HCV negative group was 31.11 months (95% CI: 22.62 - 39.61) compared to 37.66 months (95% CI: 7.19 - 68.13) for the HCV positive group. The median progression-free survival (PFS) for all patients was 18.9 months, for HCV positive patients was 15.36 months (95% CI: 13.18 – 17.54), and for HCV negative patients was 20.49 months (95% CI: 14.13 – 26.85). Age below 60 years and creatinine level less than 2 mg/dL were statistically significant for favorable disease-free survival (DFS) (p < 0.030, 0.034 respectively). Conclusions: Age, creatinine and hemoglobin levels are significant prognostic factors in MM but HCV status doesn't affect the overall survival or progression-free survival. HCV infection should not contraindicate MM therapy.


A study of a new expendable blast-cleaning material, the dolomite (DS) of the Stefani region, Viotia, Greece, was conducted. This material has been compared to a widely used abrasive in Greece, the slags (SL) of B nickel production plant. The results of the tests show that the DS provides very good scouring action and cleaning effectiveness, suggesting its applicability to a wide range of uses, mainly the cleaning and preparation of metal surfaces before coating. Moreover, the DS is proven to offer temporary anti-corrosive protection, successfully combating one of the most crucial problems, that of flash rusting of the blast-cleaned surface. The DS, by not containing any toxic substances, limits harmful impacts of blast-cleaning on both the health of workers and on the environment.


Abstract Materials that combine metallic and ceramic properties are of interest for various applications, such as surgical instruments or grinding tools. Powder technology offers the possibility to mix metals and ceramics in form of their powders and process them to complex shapes by means of powder injection moulding. Thus, different material combinations were chosen in order to demonstrate a broad applicability of this approach. The produced composite materials were characterised regarding their densities, mechanical properties and microstructures. It could be observed that the powder injection moulded samples showed rather typical densities for specimens produced by this process, up to 98·3% relative density. The mechanical properties varied strongly mainly dependent upon the materials used in the composites. Thus, the range of mechanical properties is wide and leads to various possibilities to adjust certain properties to a desired level. In combination with the possibilities of the powder injection moulding process to produce near net shape parts cost-efficiently in large quantities, these versatile composite materials can be made accessible for various applications.


The article presents a method for constructing a model of an objectoriented program in terms of multilabeled Petri nets. Only encapsulation – one of the three concepts of object-oriented paradigm – is considered. To model a different aspects of encapsulation a Petri net structured object is proposed. It consists of a Petri net defining its behavior and a set of organized access points specifying its structural properties. Formal composition operations to construct a program model from the models of its methods, classes, objects, functions, and modules are introduced and a source code translation algorithm to Petri net representation is proposed. A special section of the article considers in detail a process of model construction of a real object-oriented program (OOP). Source code of the program, figures with Petri net objects modeling different elements of the program and the resulting model of the program are presented.


Recommender systems guide people to interesting materials based on information from other people. A large design space of alternative ways to organize such systems exists. The information that other people provide may come from explicit ratings, tags, or reviews, or implicitly from how they spend their time or money. The information can be aggregated and used to select, filter, or sort items. The recommendations may be personalized to the preferences of different users.


To evaluate the efficacy of tolterodine extended‐release (ER) plus tamsulosin on lower urinary tract symptoms (LUTS) as assessed by changes in the International Prostate Symptom Score (IPSS) in men who met symptom entry criteria for both overactive bladder (OAB) and benign prostatic hyperplasia (BPH) trials.


The bachelor work is focused on buying in a particular company. The first section describes the types of stocks, supply management strategy and at the end of this part of the marketing concept of the purchase. Based on the analysis of the current state of the identified problem areas the supply process and designed new ways to solve it in terms of a reduction of stocks and the establishment of a monitoring material.


A geothermal well near East Brawley intersected a series of thin (3 to 35m) diabasic to dioritic intrusives. The petrology and chemistry of these meta-igneous rocks can provide insight into the thermal and fluid chemical characteristics of the reservoir and into the processes of magma generation at depth. A description of the rock types and their hydrothermal alteration is presented in order to increase the petrologic data base relating to this important facet of the geothermal potential of the Salton Trough and to provide a case study illustrating how detailed petrologic examination of well cuttings can provide important input in the construction of a geothermal reservoir model.


Wide Area Multilateration (WAM) is being considered as one of the primary backup sources of air traffic surveillance to Automatic Dependent Surveillance-Broadcast (ADS-B) in the National Airspace System (NAS). Radar is currently the primary source of air traffic surveillance, with ADS-B poised to succeed radar leading into the FAA ADS-B Out mandate in 2020. WAM service could serve as both a transition to full ADS-B service and a cost-saving backup surveillance alternative to radar maintenance and expansion. One of the challenges associated with WAM is the accuracy of the aircraft's reported altitude. After engaging in a trade study to investigate various alternatives to correcting aircraft altitudes in a wide region for the FAA Colorado WAM Phase II program, Exelis determined that the aircraft altitude errors could be reduced significantly (less than 200') by integrating the Rapid Update Cycle (RUC) weather data grid generated by NOAA. The altitude correction trade study for WAM approach and results are discussed and analyzed.


Rural schools are fighting for survival. Competition for excellent teachers is fierce. This article discusses recruitment and retention strategies found in the literature. Suggestions are made for innovative recruitment and retention techniques. An underlying task requires communicating with prospective teachers the benefits of teaching in rural schools.


Surface of BaTiO3 particle was chemically modified using silane coupling agent (KH550) in order to improve its compatibility with polyvinylidene fluoride (PVDF) matrix polymer, and therefore, expectable microstructure and dielectric property of the BaTiO3/PVDF composites were acquired. Infrared spectra reveal an obvious interaction between BaTiO3 and PVDF induced by the addition of KH550 coupling agent, and the interaction was also confirmed by the observation of morphology of fractured surface of the BaTiO3/PVDF composite when the concentration of KH550 is around 1.0wt%. Crystal lattice parameter of BaTiO3 in the composite was also changed because of the interaction. Finally, increased dielectric constant in the PVDF matrix composite with BaTiO3 treated by 1.0wt% KH550 was found.


We present a new morphologic edge detection method using a multiscale approach for detecting edges of various fineness under noisy conditions. The comparative study reveals its superiority over other morphologic edge detectors.


This paper deals with the problem of control of an aluminum recycling unit in reverse logistics. The unit studied is in open loop. It's assimilated to a machine producing a single type of products and is subject to random failures and repairs, fueled by a random return rate of aluminum and supplying a constant customer demand rate. Due to the presence of random breakdowns of the machine and the constraints related to customer satisfaction, it is imperative to determine an optimal policy of production in order to insure the customer demand satisfaction. The objective of this study is to determine the production and disposal policies in order to minimize the overall production cost. A corresponding optimal stochastic model has been developed and leads to Hamilton-Jacobi-Bellman equations describing the optimality conditions. A numerical solving method has been used and led to an optimal policy which is of the Hedging Point Policy type (HPP).


This paper analyzes the curricular reform and courses offering system of business English in Hubei Science and Technology Vocational College,it puts forward the suggestions to meet the development of business English.


This article deals with a relationship between derived categories of modules over some partially ordered sets and triangulated categories arising from quasi-homogeneous isolated singularities. It produces heuristics for the existence of derived equivalences between posets, using the geometric category as an auxiliary intermediate. The notion of Weight plays a central role as a simple footprint of the derived categories under consideration.


Percolation phenomena, which include the ac and dc conductivity, dielectric constant, and magnetoresistance, are studied in a series of seven cellular composites, consisting of small conductor particles embedded on the surface of larger insulator particles. Carbon black (ground and unground), graphite, graphite\char21{}boron-nitride, niobium carbide, nickel, and magnetite $({\mathrm{Fe}}_{3}{\mathrm{O}}_{4})$ powders were the conducting components with talc-wax powder as the common insulating component. The dc conductivity results were fitted to the standard percolation equations and to a two-exponent phenomenological equation, which yields the percolation parameters ${\ensuremath{\sigma}}_{i},$ ${\ensuremath{\sigma}}_{c},$ s, t, and ${\ensuremath{\varphi}}_{c}$ in the ideal limits. Both universal and nonuniversal values of s and t are measured in the systems. Close to the percolation threshold $({\ensuremath{\varphi}}_{c}),$ the ac conductivity $({\ensuremath{\sigma}}_{\mathrm{mr}})$ and the dielectric constant $({\ensuremath{\varepsilon}}_{\mathrm{mr}})$ are found to scale as ${\ensuremath{\sigma}}_{\mathrm{mr}}\ensuremath{\propto}{\ensuremath{\omega}}^{u}$ and ${\ensuremath{\varepsilon}}_{\mathrm{mr}}\ensuremath{\propto}{\ensuremath{\omega}}^{\ensuremath{-}v}.$ All these exponents are examined using the most recent theories and compared with previous studies. The dielectric constant exponent ${(s}^{\ensuremath{'}}),$ from ${\ensuremath{\epsilon}}_{\mathrm{mr}}\ensuremath{\propto}({\ensuremath{\varphi}}_{c}\ensuremath{-}\ensuremath{\varphi}{)}^{\ensuremath{-}{s}^{\ensuremath{'}}},$ is shown to be frequency dependent. The exponents ${g}_{c}$ (magnetoresistance) and ${t}_{m}$ (from magnetoconductivity) in composites are not yet clearly understood but these and previous results show that ${t}_{m}gt.$ dc scaling is shown in a real composite comprising ${\mathrm{Fe}}_{3}{\mathrm{O}}_{4}$ and talc wax.


Elemental sulfur is used to cross-link heavy coker gas oil (HKGO) with only 0.44 wt% olefinic hydrogen content in the absence of solvent; subsequent pyrolysis yields sulfur-doped porous carbon with Brunauer–Emmett–Tell (BET) surface area (s.a.) around 1714–1785 m2 g−1.


Abstract #6052 Introduction: The combination of Computed Tomography (CT) and [18F] Fluorodeoxyglucose - Positron Emission Tomography (FDG-PET) scanning technologies provides a more complete picture of disease activity than CT alone. Circulating tumor cell (CTC) levels were shown to be more predictive than standard imaging (CT) when used to monitor disease progression in women with metastatic breast cancer (MBC). We performed a retrospective study to compare the ability of combined FDG-PET/CT to CTC to predict clinical outcomes in patients treated for MBC.
 Methods: One hundred and two MBC patients with either measurable or evaluable disease starting a new line of therapy had CTC counts and FDG-PET/CT scans done at baseline (BL) and at mid-therapy. CTC: 7.5mL of blood collected in CellSave tubes at both time points was assayed for CTC using the FDA approved CellSearch® System. Patients were categorized as having a favorable ( 50%. Changes in CTC and SUV at mid-therapy were compared to progression free survival (PFS) and overall survival (OS).
 Results: CTC: 50% (51/102) patients had ≥5 CTC at baseline (BL). At mid-therapy (median 2.5 months from BL), 21/102 progressed (≥5CTC) with a median PFS of 2.8 months vs. 7.8 months for those with no progression ( 2nd line chemotherapy and triple-negative disease.
 Conclusion: ≥5 CTC and/or no response at FDG-PET/CT at mid-therapy accurately predicted significantly shorter OS. Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 6052.


In article results of researches of invasive species Ambrosia trifida L. are given. The features of the biology and distribution of ambrosia are shown. The study of biological features of Ambrosia trifida L. plays an important role in the understanding of its invasive success in the new habitats.The morphometric parameters plants of ambrosia are characterized by high values of coefficient of variation, but in comparison with neighboring regions the level of variability of morphometric parameters is relatively low. The lowest values of most morphometric parameters marked in cenopopulation Krasnoyarka. Accordingly, the lowest values of coefficient of variation in the populations, located along the roads, and highest in the populations, occupying the floodplain habitats, ravines, croplands. Among the indicators of morphometrics greatest variation have plant height, sheet width, length of the root, number of lateral branching, and among generative organs the length of the inflorescence. Also it is established, this spesies on the territory of the Orenburg region is anthropotolerant, populating various synanthropic habitats, moreover, the seizure of new territories is proceeding successfully. There is an active introduction of spesies in natural communities or disturbed community with displacement of indigenous species, that brings to so-called to «floristic pollution of the territory». Lists new centers of localization on the territory of the Orenburg region and compiled a list of hotbeds, need control. A total of reliably detected ninety one of cenopopulation. The reason for such wide distribution of A. trifida can serve as a violation of the processes of self-regulation of ecosystems under the influence of anthropogenic impact. A map of the distribution of species is made. Further extention of Ambrosia trifida secondary areal in the region is predicted.


The invention of the program information of broadcast information of each channel to begin after relates to an apparatus and method for detecting information of a digital broadcast that starts at the other channel for the digital broadcasting using a mobile terminal, an end broadcast receiving an electronic program guide obtaining and storing, and a program switching by checking the program switching timing of each channel is determined by the digital broadcasting management unit to determine program switching timing of each channel to check the program information, the digital broadcasting output the digital broadcasting of management omitting the step of the program by confirming the program conversion information using a mobile terminal including a controller for processing to output the information, terminate the digital broadcasting in digital broadcasting is being watched when checking information of the program broadcast by the other channels when can do. Digital broadcast channel information, EPG, broadcast information


Entities composing web pages to provide services over the Hypertext Transfer Protocol (HTTP) frequently have the problem of not knowing what Multipurpose Internet Mail Extensions (MIME) types have handlers installed at a user's browser. For example, whether an Internet Open Trading Protocol (IOTP) or VRML or SET or some streaming media handler is available. In some cases they would want to display different web pages or content depending on a MIME handler's availability. This document summarizes reasonable techniques to solve this problem for most of the browsers actually deployed on the Internet as of early 2000. It is intended to be of practical use to implementors during the period before the wide deployment of superior standards based techniques which may be developed.


In this issue of the European Journal of Anaesthesiology, van Gelder et al. present a cross-sectional survey which aims to describe the practice of preoperative cardiac testing among European anaesthesiologists. On the basis of 359 responses from 17 countries, the investigators found considerable variation in the reported frequency of, and indications for, preoperative testing. Additionally, half of respondents reported not adhering to practice guidelines for preoperative testing, and most supported reducing, if not eliminating, routine preoperative testing.


With the help of a Pade technique, it is shown that, given the two requirements that the equation for the hard spheres r.d.f. should involve only convolution integrals (as in the PY and HNC equations) and that it should obey the internal consistency criterion imposed by the equality of the pressures calculated using the virial or the Ornstein-Zernike theorem, an integral equation can be derived without resorting to any postulate regarding its functional form. This equation leads to an equation of state which is satisfactory except in the vicinity of the Alder transition where it under-estimates the pressure by nearly 4 per cent. A detailed examination of the fourth virial coefficient reveals some possible reasons for the validity of the integral equation derived in the present paper.


The purpose of this study was to review the program of public elementary and secondary school finance in Newfoundland from 1960-61 to 1970-71. -- At a more specific level, the purposes of the study were: (1) to make an analysis of 1960-61 to 1970-71 trends in provincial revenues for public elementary and secondary education, (2) to make an analysis of provincial procedures for distributing provincial funds to local school boards, (3) to describe provincial organizational relationships - especially with reference to capital expenditures for public elementary and secondary education, (4) to make an analysis of 1960-61 to 1970-71 trends in local revenues for public elementary and secondary education, (5) to trace the development of local taxation for public elementary and secondary education during the period from 1960-61 to 1970-71, (6) to describe from the literature on public and school finance the foundation program concept of financing education, (7) to investigate the use of the foundation program in financing public elementary and secondary education in other Canadian provinces, (8) to make an analysis of 1960-61 to 1970-71 trends in public elementary and secondary school expenditures, (9) to examine the impact of increased price levels and increased enrollment on public elementary and secondary school expenditures during the period from 1960-61 to 1970-71, and (10) to make a statement of implications for future financing of public elementary and secondary education in Newfoundland. -- The data used in the study were obtained from: (1) Annual Reports of the Department of Education, (2) Annual Financial Reports of School Boards, (3) Public Accounts of the Province, (4) Newfoundland Federation of School Boards, (5) Provincial Association of School Tax Authorities, (6) Denominational Education Committees, (7) provincial statutes, (8) Canada Yearbooks, (9) other Statistics Canada publications, (10) regulations, files, and records of the Department of Education, and (11) Royal Commission Reports. -- The principal method of research utilized in the study was the normative - survey method. The historical and analytical methods were also used at various stages of the study. The study presented its data in both descriptive and tabular form. -- The findings of the study support the following conclusions: (1) In spite of substantial increases in expenditure for public elementary and secondary education in "current dollars" over the period from 1960-61 to 1970-71, the increases in "constant dollars" have not been as dramatic; (2) The operating expenditure per student in public elementary and secondary schools of Newfoundland is substantially lower than that of any other Canadian province. Hence, there is ample justification for seeking federal assistance to public elementary and secondary education in this province); (3) There is a definite need for a systematic method of raising funds for public elementary and secondary education from local sources; (4) Newfoundland's school grants system has grown to become cumbersome by successive additions of special grants. Because of this, there must be a consolidation of grants based on the principles of the foundation program concept of education finance; and (5) The lack of a stable source of local revenue in Newfoundland school districts has discouraged school boards from going beyond the standard provincial program supported by provincial grants to school boards. -- The study identified the following three areas of further research): (1) the development of an educational price index specifically designed to measure the change in price levels of educational inputs in Newfoundalnd, (2) an investigation of the extent of differentials in cost per pupil of educating elementary and secondary pupils in Newfoundland school districts, and (3) a cost - benefit study to determine the effectiveness of Newfoundland schools or school systems.


Mobile identity management system using static and dynamic authentication, the main use of static authentication is to use user name and password to authenticate users, at the same time, dynamic authentication use verification code to improve security authentication, in order to ensure that the load information will not be disclosed. The system uses the SSH framework technology, and using JSP technology and Oracle database to develop the system.


As a key technology that realises decentralised and highly trusted database management, Blockchain has recently attracted extensive attention. However, the high latency and low throughput in highly concurrent environments is the main performance bottleneck of Blockchain technology, and thus delays its deployment. Although multiple studies have been dedicated to solving the problem of low throughput in Blockchain, they only paid attention to the scenarios with large transactions volume while neglecting the issue of conflicting transactions. In this paper, we demonstrate that the conflict transactions will not only decrease the computing efficiency of Endorser but also slow down the performance of Hyperledger Fabric. Besides, we propose a Cache enhanced Endorser solution to tackle conflict transactions in Hyperledger Fabric vl.0. The experimental results show that our approach can reduce the workload of a node by up to 80%, shorten the turnaround time of transactions by 55%, and improve the computational performance of Endorser up to 1.9 times.


Simple Summary Cancer stem cells (CSCs) are known for their ability to survive under stressful conditions. To this aim, they use autophagy to recycle their altered organelles and proteins by addressing them toward a lysosome for their degradation. CSCs can also communicate with their environment using the secretion of extracellular vesicles (EVs) which carry information, strengthening their ability to survive under such conditions. Both mechanisms are known for using common actors and have been described as implicated in colorectal cancer (CRC). However, CSCs remain difficult to target due to the lack of specific markers identified, especially in colorectal cancer. Then, the study of the crosstalk between autophagy and the secretion of EVs seems crucial regarding a better targeting of CSCs. Abstract Autophagy is a homeostatic process involved in the degradation of disabled proteins and organelles using lysosomes. This mechanism requires the recruitment of specialized proteins for vesicle trafficking, that may also be involved in other types of machinery such as the biogenesis and secretion of extracellular vesicles (EVs), and particularly small EVs called exosomes. Among these proteins, Rab-GTPases may operate in both pathways, thus representing an interesting avenue for further study regarding the interaction between autophagy and extracellular vesicle machinery. Both mechanisms are involved in the development of colorectal cancer (CRC), particularly in cancer stem cell (CSC) survival and communication, although they are not specific to CRC or CSCs. This highlights the importance of studying the crosstalk between autophagy and EVs biogenesis and release.


The Drake equation is a calculation providing an upper bound on the likely number of intelligent species in our galaxy. In order to reconcile a potentially high occurrence of intelligent extraterrestrial species with the current non-observation of them, we frequently resort to some Great Filter which represents some inevitable, cataclysmic fate (such as nuclear war, pandemic, or asteroid impact) that tends to await enough worlds to negate the expectation that the galaxy ought to be teeming with intelligent life. This paper is intended to examine one potential Great Filter for electronic-based civilizations, the impact of a Carrington-class coronal mass ejection (CME) from the Sun. Carrington-class CMEs are classified as "once in a century" events caused by our Sun; this appears to place a time limit, following the development of a civilization dependent on electronic devices, either for hardening electronics against the geomagnetically induced currents that result from CMEs or for beginning interplanetary colonization.


This study mainly focuses on container loading problem with the constraint of limited rotation.Based on Pisinger's tree-search heuristic algorithm,we take into account some actual constraints on cargoes,e.g.limited rotation and balance problems etc.,in our improved algorithm.In order to get satisfied calculation time,proper width and depth for the tree-searching are specified.In addition,the layers and the strips of the cargoes may be exchanged to meet the constraint of the balance without decreasing the loading efficiency.The experiment of the improved algorithm shows that the rotation constraint has certain passive effect on container loading efficiency,however,the final loading efficiency with limited rotation is still satisfied and the operation time is reasonable.


Abstract : One-hundred and four Bucknell University undergraduate males were designated high and low fear of failure (FF) according to the Hostile Press (HP) scoring system of the TAT (Birney, Burdick and Teevan, 1964). An affiliation Preference Questionnaire and Work Condition Preference Questionnaire were administered to Ss during the rest period of an achievement situation. There was no difference between the affiliation preference of high and low FF Ss. The results showed that high FF Ss preferred to work in isolation to a greater extent than low FF Ss and that low FF Ss preferred to work in a communal setting to a greater extent than high FF Ss. The results were discussed in terms of the relationship between the social contingencies of different work conditions and high FF S's fear of failing in the eyes of others. (Author)


This paper investigated and analyzed the situation of college PE informatization in Anhui Province with the methods of literature data,questionnaire and mathematical statistics.Furthermore,it proposed some countermeasures in view of the existing problems,in order to provide some references for the information development of college physical education.


In this paper, a new robotic assembly system has been successfully implemented to conduct precision assembly tasks by using a robot with relatively poor positional accuracy. The peg-into-hole inserting assembly processes are analysed under more general conditions to gain better understanding of the processes and reveal the features of automatic assembly operation. A compensation scheme is proposed for the robot's compliant deformation from links and joints. Based on the analysis a new-type compact flexible wrist is subsequently designed. Finally, the insertion tests were made on the system through the use of the assembly strategy suitable to the above-obtained parts mating theory and the experimental results show the feasibility of the system.


In this paper, a re-confîgurable 12/13/14-bit SAR ADC based on a 12-bit ADC core is presented. A novel residue-boosting algorithm is developed to increase the bit resolution of a SAR ADC up to 2 bits without significant additional area and power. In the 12-bit mode, the 65nm prototype shows both DNL and INL of about +/−0.5 LSB at 4MSPS, and in 14-bit mode, DNL and INL are about +/− 1 LSB and +/− 2 LSB at 2MSPS. ENOB is 11.5 bit and 13 bit for 12-bit and 14-bit mode each. The area of the ADC is 0.085mm2.


In this thesis a case study is presented, which explored what structural and visual aspects of a sales performance management tool's user interface that generated most recurrent problems for novice ...


We construct a series of distinct-element models that consist of bonded assemblies of elastic particles that simulate the brittle deformation associated with large-scale, fault-related folding over a rigid footwall. The initial rock mass is simulated by a series of discrete, circular, elastic, frictional particles, bonded in shear and tension and capable of progressive fracture during loading. This produces discontinuities within the simulated rock mass: Regions of intact material are separated by discrete faults or fault zones. The simulations are fully dynamic. Material properties are assigned as microproperties of and between particles; elastic stiffness, friction, and bond strength (shear and tensional) describe particle interactions. Because the macroscopic elastic, failure, and flow properties are not directly determined by the microproperties, uniaxial and biaxial compression tests must be conducted on a representative specimen to determine macroscopic parameters, such as unconfined compressive strength, Young's modulus, friction angle, and cohesion. To determine the effect of growth strata on the evolution of the underlying fold, growth strata with thicknesses equivalent to 0%, 25%, 50%, 75%, and 100% of the elevation of the associated anticline above the upper footwall flat are added to the upper surface of the models. The presence or absence of growth strata has a significant effect on the final geometry of the associated fault-related fold. The growth strata provide resistance to forelandward translation, causing folds to tighten from open, gentle ramp anticlines with no or thin growth strata to strongly overturned fault-propagation-type folds with thick growth sequences. The nature and intensity of fracturing is strongly affected by growth-strata thickness. All models have effectively identical early stages, as a result of thin or no growth, and initial deformation at the thrust ramp is always by back thrusting. This changes with increased burial. (1) With no growth strata, back thrusting continues, although fault dips become shallower with time. (2) With intermediate thicknesses of growth strata, back thrusting gives way to, or alternates with, bedding-parallel shear. (3) With thick growth strata and thus high confining pressure, brittle deformation is inhibited and replaced by elastic deformation of the particles. These models produce realistic-looking packages of growth strata. Well-developed growth triangles are common in backlimbs, and are cut by the faults that originate in the pregrowth strata. The growth strata commonly show angular unconformities and stratigraphic pinch-outs. Overturned forelimb growth strata are significantly deformed, recording brittle deformation associated with progressive growth of the underlying fold.


The paper reviews from archival sources the experience gained by the UK Agriculture Departments in combatting the damage caused by an alien species, the grey squirrel. Insights are provided into the circumstances and significance of the Grey Squirrels Order, 1937, wartime regulations, the free cartridges and tail-bonus schemes and grey squirrels (warfarin) Order of 1973. At times pro-active, policy was more usually driven by the need of Ministers to be seen responding to pressure from farming and forestry, as communicated through such powerful political figures as the Prime Minister himself, Harold Macmillan. Such instances of debate as to the optimal level of pest regulation afforded opportunity not only for scientific study, but for scientists themselves to participate in discussion as to the weight to be given in policy-making to the knowledge, understanding and powers of prediction thereby gained.


Abstract : An increasing amount of interest has evolved in VHF/UHF SAR applications. These types of radars have proven to be a very powerful method for underground and obscured object detection. In this paper we analyze the possibility of a spaceborne P-band SAR system, based on the experience gained from the analysis of the experimental airborne P-band SAR (E- SAR)system of DLR. We address possible methods and filters for effective Radio Frequency Interference (RFI) suppression, polarimetric and radiometric calibration procedures. We also assess the problems concerning the image quality degradation due to ionospheric propagation effects based on several simulation models.


Abstract—This article presents the application of support vector machines to adaptive power system stabilizer design in a multi-machine power system based on the harmony search algorithm. Data from a multi-machine power system are the input features of the support vector machines. Support vector machine parameters and power system features are simultaneously optimized by harmony search based on the k-fold cross-validation technique. The proposed algorithm is trained by the optimal support vector machine parameters and optimal power system features. Power system stabilizer parameters produced by the proposed algorithm can be adapted by various operating conditions when the power system operates either inside or outside the training ranges. Simulation studies in the IEEJ Western Japan ten-machine power system demonstrate that the proposed algorithm is far superior to conventional power system stabilizers with fixed parameters and those designed by a robust coupled vibration model under various operating conditions and severe disturbances.


Due to the characteristics of wind intermittent, fluctuating, anti peak, and large prediction error, large-scale wind power access to the grid has brought negative impact on the planning and operation of the power grid. The contradiction between the power load and the peak and valley of the heating load expands the difficulty of the power grid to reduce the wind power. In addition, the thermoelectric coupling characteristic of the cogeneration unit determines the limit of the electric output regulating range of the thermoelectric unit, and the planning and operation policy of the thermoelectric co production unit with thermal power intensifies the problem of the high incidence of the discarded wind in the heating season. According to the analysis of the energy flow model of the electric heating combined system, the energy flow method is used to optimize the dispatching model and improve the capacity of wind power consumption during the heating period. The results show that the use of the electric heating station can increase the low valley electric load, reduce the thermal power output of the unit and leave the space for the wind power network. The indoor temperature of the user affects the heat load, and then affects the total amount of the wind power consumption, and the optimal scheduling results calculated by the optimized scheduling model considering the constraints of the heat transfer link are more accurate and feasible.


A method and a system for indicating a fuel efficiency in a vehicle is provided that includes a density sensor configured to measure the density of a fuel mixture stored in a fuel tank. In addition, a controller is configured to derive the mix ratio related to the fuel mixture via the density measured by the density sensor and change a reference value of a fuel calculation logic based on the mix ratio. In addition, the controller is configured to determine the fuel efficiency based on the changed reference value.


Increased insulation has led to higher concentrations in homes and offices of toxic chemicals caused by emissions from synthetic building components. Recent NASA research regarding future interplanetary manned spacecraft has shown that certain plants can absorb gasses, reducing indoor air pollution. After working with water purifying water hyacinths, Dr. B. C. Wolverton at NSTL developed a carbon/plant filter system to remove chemicals, smoke, etc. Two companies have commercialized the system. Bio-safe provides plants, a bed of activated carbon and an air pump installed near the plant's roots. Pollutants are trapped by the charcoal and either digested by the roots or broken down by microorganisms. Purified air is then directed back into the room. Applied Indoor Resource Company markets Bio-Pure, which includes plants on a layer of patented soil medium with activated carbon. Legumes and mosses filter the air; a blower moves air through the filtering system for cleansing by microorganisms. Research at NSTL continues, and the system may eventually be enlarged.


The synthesis of three difuryl analogs of the oxophlorins is described. In common with the tetrapyrrolic oxophlorins, these compounds favor the keto tautomers and little, if any, of the enol tautomers are present in neutral solutions. Unlike the tetrapyrrolic systems, the difuryl oxophlorins give well resolved nmr spectra. Attempts to extend these studies to the synthesis of dithienyl oxophlorin analogs were unsuccessful


In spite of concern and prognoses that the economic recession and democratic depression will cause sharp decrease of people wishing to study the admission commission of the Faculty of Engineering in the summer of 2009 received a considerable number of applications from entrants for full-time studies. It shows that young people evaluate education as long-term investment for their future. Though, in part-time studies sharp reduction of students can be observed. It indicates that the form of part-time studies at the present economic situation has exhausted its possibilities and the faculty should think about future and offer other forms of organisation of studies. The authors of the article are working with the first year students and through inquiries get an insight in the problems of the procedure of the study process and try to find solutions of them.


Alice Walker's"The Abortion"is about some events in the lives of a Black married couple living in a small town in the southeastern United State.Walker's portrayal of the destruction of the seemingly happy marriage reveals her"contrariness"in her literary work.From hooks's feminist point of view,the paper focuses on the destruction of the Black family and the process of the awakening of its female protagonist's self - awareness and self-assertion.


The self-similarity paradigm enables the analysis of scale-free temporal dynamics and has been widely used in a large set of real-world applications. However, in a multivariate setting, delays amongst components significantly impair the estimation of scale-free parameters. The first framework for the modeling, detection and estimation of delay parameters and for the joint estimation of scale-free parameters is proposed here. It is assumed that a single realization of a multivariate, self-similar time series is available. Use is made of ℂ-valued wavelets and, based on the imaginary part of the wavelet coherence, an original bootstrap-based delay estimation procedure based is constructed. Moreover, a consistent wavelet eigenanalysis-based semiparametric estimation for scale-free parameters that accounts for delay is defined. Monte Carlo experiments conducted over various instances of the model show that the proposed methodology enables the detection of delays with high probability and provides very satisfactory estimates of the delay and scale-free parameters.


LAN connectivity, transparent WANconnectivity, and the required suite of applications(DOS, Windows, X-Windows, WWW)was also atechnical challenge. This was not solved untilWindows95becameavailable late in 1995.Another major factor encountered was the aginginner-city infrastructure. Many of the buildings inthe community were built in the 1920's or before.Sites sometimes


Based on the review and conclusion of the practial course construction of GMDSS Communication, this paper develops the reflection on how to intensify and improve the course construction, especially on the construction of the essence course.


For the cellular neural networks with piecewise constant argument, a sufficient conditions is obtained for the networks to be global exponential stability by using Halanaytype inequalities. Moreover, the unique existence and the module containment of almost periodic solution for this kind of almost periodic system is proved under the same conditions by employing the fixed point theorem.


The author recently derived an integral equation for the axial electric field at the pipe radius in the presence of an azimuthally symmetric cavity of arbitrary shape in a beam pipe of circular cross section. In the present work, the author analyzes the case of N cavities and explores the high-frequency behavior for large N, in an effort to understand the transition to a periodic structure Not unexpectedly, the result depends critically on which of the limits (k to infinity or N to infinity ) is taken first.<<ETX>>


To date, the legislation on social security in many cases grants the right to receive social security in the absence of employment. It should be understood that in addition to those measures of social protection and social security that are directly related to the status of the unemployed, in particular, unemployment benefits, the right of social security has a number of payments that, although they do not directly imply protection from unemployment, but as a consequence of the fact that they are provided in the absence of employment, respectively, may be the source of income during the period when the person is unemployed. In this regard, the article draws attention to the recipients of the survivor's insurance pension, caring for disabled children, brothers, sisters of the deceased breadwinner under the age of 14, who themselves receive this pension. Their receipt of an insurance pension in case of loss of a breadwinner is currently associated with a number of problems in determining the amount of insurance pensions in case of loss of a breadwinner.


This article mainly researched the influence degree of crushing method,backfill soil water content,grinding times on compactness. Results show that the primary and secondary order influencing subgrade backfill compactness is backfill soil moisture,crushing method,grinding times. The main factor is backfill soil moisture content. Optimal value is the maximum moisture content of the backfill. Non-significant factors are crushing method and grinding times. The best crushing method is the combination of vibrating rolling and static pressure.


Abstract In order to study the semi-conductive characteristics of carbon black-filled ethylene–propylene–diene monomer (EPDM) compositefilm, which is used for measuring occlusal force, composite samples with volume ratios of carbon black to EPDM ranging from 30%to 70% were prepared. The process of making a composite film consists of two steps, which involve the preparation of a slurry com-position and the fabrication of a thin film using solution casting and a lamination process. To prepare the slurry composition, we dis-persed carbon black nanoparticles into an organic solvent before mixing with an EPDM solution in toluene. The mechanical andelectrical properties of the resulting carbon black-filled EPDM film were then investigated, and the results showed that the electricalresistance of a film decreases with the increase in the carbon black content. Furthermore, improved elastic recovery was observed aftercross-linking the EPDM.Keywords: Carbon black, EPDM, Solution process, Electrical resistance, Elastic recovery


The sensor-based human activity recognition has been wildly applied in behavior tracking, health monitoring, indoor localization etc. Using activity continuity to assist activity recognition is an important research issue, in which the activity transition matrix which describes the activity transformation in real scenarios is the most important parameter. Aiming at the problem that the current classic transition matrix learning algorithm cannot fuse weights of sample classification results, a weighted transition matrix learning algorithm is proposed in this paper. First, the basic definitions of an improved Hidden Markov Model (HMM) which fuses weights of classification results are given. Then, the recursive formula of transition matrix learning is derived, and the learning algorithm W-Trans is put forward. Finally, the proposed algorithm is simulated with the public data sets. The evaluation results show that the proposed algorithm outperforms the classical Baum-Welch algorithm under evaluation metrics of both the cosine similarity and the euler distance. By applying W-Trans to current activity recognition post-process methods, the advantage of our method is verified.


The present situation of our army's universal firearms packaging and the current existent problems were briefly introduced. The countermeasures of developing universal firearms packaging were put forward.


The invention relates to an actuator for electromagnetic valve control with a magnetic field sensor and a magnetic encoder having device for determining position of the armature plate, wherein the magnetic field sensor and the magnetic encoder are surrounded by a magnetic shield.


The paper has determined the suitability of membrane processes (UF ultrafiltration, UF, and nanofiltration, NF) for the purification of waste streams, so-called backwash water, obtained from washing filtration beds in a swimming pool water system. The backwash water samples were taken from the circuits located in two indoor facilities with a different purpose of the basins. Moreover, the samples were characterized by varying quality, as described by selected physicochemical parameters (such as turbidity and ultraviolet absorbance UV254). Commercial membranes were used for the tests. The transport-separation properties of the membranes were determined based on the volumetric flux of the permeate. In addition, backwash water samples before and after the membrane process were subjected to toxicological assessment using the Microtox® screening test. The performed processes contributed to a significant reduction in turbidity and the value of UV254 ultraviolet absorbance, both in the ultrafiltration and nanofiltration processes. Whereas, significant differences in transport properties were noted within individual processes. A great influence of backwash water quality, including physicochemical parameters, on the course and results of the membrane filtration processes was demonstrated. In all of the nanofiltration cycles carried out, the removal of the toxic properties of the backwash water with respect to bacteria in the Microtox® test was found. Nevertheless, samples with high values of resultant physicochemical parameters after the ultrafiltration process were still characterized by high toxicity. Pressure membrane processes show high effectiveness in the removal of contaminants from backwash water. However, it is necessary to introduce supporting processes aimed at reducing membrane pore blocking by deposits and organic compounds, and in the case of ultrafiltration, assuring the safety of the purified stream in terms of the toxicological effect.

http://www.jeeng.net/pdf-74282-12240?filename=THE USE OF MEMBRANE.pdf


SO FAR, NO TRUE GENERICS OF prairiel have been found on current topographical maps of Michigan.2 Yet at one time there were a good number of named prairies in the state, and the inhabitants used the word considerably. For this information I am grateful to Professor Albert H. Marckwardt, who called my attention to Albert F. Butler's article entitled "Rediscovering Michigan's Prairies."3 In principle, some of Butler's observations hold true outside of Michigan, probably applying more to Ohio, Indiana, Illinois, Wisconsin, Minnesota, Iowa, Oklahoma, Kansas, Nebraska, North Dakota, and South Dakota than elsewhere. On page 268 of the September, 1947, installment Butler says, "The French fur traders and hunters ... [gave] us this heritage not only of a general topographical term, but names for specific prairie areas of Michigan Portage Prairie, Terre Coupe Prairie, Prairie Mouillee, Prairie Ronde, Grand (Grande) Prairie, and possibly others." He goes on (ibid., pp.275-'76) to describe the conditions that affected the use of the expression in this region: "In many cases, the need for prairie names came before the· need for village names and in a certain period, especially in the 1820's and 1830's, one spoke of prairies in giving directions, rather than employing the names of


The article introduces and analyzes the contents and characteristics of the book Internet Medical Information Retrieval and Publication edited by researching librarian Li Jian kang.As an objective estimation,the book is considered to be frontier standing and precisely focused with brand new scientific and applicable contents and practical examples.It is the most recommendable book nowadays on internet information searching with striking creativity and novelty.


The Farsite distributed file system provides availability by replicating each file onto multiple desktop computers. Since this replication consumes significant storage space, it is important to reclaim used space where possible. Measurement of over 500 desktop file systems shows that nearly half of all consumed space is occupied by duplicate files. We present a mechanism to reclaim space from this incidental duplication to make it available for controlled file replication. Our mechanism includes: (1) convergent encryption, which enables duplicate files to be coalesced into the space of a single file, even if the files are encrypted with different users' keys; and (2) SALAD, a Self-Arranging Lossy Associative Database for aggregating file content and location information in a decentralized, scalable, fault-tolerant manner. Large-scale simulation experiments show that the duplicate-file coalescing system is scalable, highly effective, and fault-tolerant.


Objective To explore the clinical characteristics,surgical treatment,perioperative management,and prevention of postoperative complications for the elderly patients with colorectal cancer so as to improve surgical curative effects.Methods The clinical data of 56 elderly patients with colorectal cancer from January 2008 to December 2010 were analyzed retrospectively.Results All the patients were treated surgically.56 patients were followed for 1 to 28 months and the follow-up rate was 100%.The survival rate was 85.71%(48/56)for 1 year and was 46.43%(26/56)for 2 years after surgical operation.38 patients had postoperative complications,including 12 cases of pulmonary infection,5 cases of infection of incisional wound,3 cases of intestinal fistula,3 cases of hypertension,6 cases of cardiac inadequacy,5 cases of hepatic inadequacy,2 cases of acute renal failure,and 2 cases of stress ulcer.No death was observed due to surgery.Conclusions The elderly patients with colorectal cancer have no characteristic clinical manifestations,but have many comorbidities,which increase the risk of surgical operation.However,the surgical operation is still a good treatment method for elderly patients with colorectal cancer.Strengthening perioperative management,and preventing and treating comorbidities actively can improve the surgical success rate,and reduce complications and mortality rate.


This study was performed to examine the uncertainty, stress, and anxiety of the mother with a sick child. A self-administered Questionnaire survey was carried out for 167 mothers.
The mean uncertainty score adjusted by age of child was 56.0 in the mothers with the children suffering from cancer and 50.4 in the mothers of sick children with other disease than cancers. The mean stress score adjusted by age of child was 106.0 in the mothers of the children with cancers and 70.5 in the mothers of sick children with other disease than cancers. The mean anxiety score adjusted by age of child was 53.6 in the mothers of the children with cancers and 49.9 in the mothers of sick children with other disease than cancers.
In bivariate analysis, uncertainty score in the mothers of sick children without cancers was significantly different according to the age of the child, mother's perception of the severity for child's disease. The stress score was significantly different according to the perceived health status of the mothers of the child with cancer and significantly different according to the age of the child, mother's perception of the severity for child's disease, admission numbers of child, and the perceived health status of the mothers of sick children without cancers. Anxiety levels were significantly different according to the children's ages, economic status of the family of the mothers of children with cancers and significantly different according to the ages and admission numbers of the children in the mothers of sick children with other disease than cancers.
In multiple regression analysis, uncertainty scores in the mothers of sick children without cancers were higher in the cases of older than 7 years of ages and when mother's perceived severities for children's diseases were increasing. Stress scores in the mothers of children with cancers were higher when mother's perceived health status was not healthier and in the mothers of sick children without cancer, stress scores were higher as admission numbers of child and uncertainty scores were increasing, and when mothers' perceived health status was not healthier. Anxiety scores in the mothers with children suffering from cancers were higher in the cases of older than 7 years of age and as uncertainty scores were increasing. In the mothers of sick children without cancers, anxiety scores were higher as uncertainty scores were increasing.
In consideration of above findings, it appears that controlling the uncertainty of the mothers with sick children is necessary for an improved and efficient nursing intervention.


The invention provides a polyester hot melt adhesive and a preparation method thereof, comprising the steps that: (1) in the presence of a catalyst, a transesterification is carried out between a dimethyl terephthalate and a diol; (2) a isophthalic acid, a aliphatic dicarboxylic acid and a stabilizer are mixed with the yield products of the step (1), a decompression and a co-condensation process are carried out so as to obtain a copolymer; (3) the mixture of a sorbic acid metal salt and the copolymer of ethylene KEYI acrylic acid are added in the yield products of step (2), then the copolymer is modified so as to obtain the polyester hot melt adhesive. The invention adopts the sorbic acid metal salt and the copolymer of ethylene acrylic acid to modify the colopolymer. The polyester hot melt adhesive obtained therefrom has the advantages of strong bond performance, positive effects of water cleaning and dry cleaning resistances, short opening time and fast solidification. The polyester hot melt adhesive is especially suitable for a production assembly line which calls for rapid bonding.


Abstract : This thesis deals with initial boundary value problems for incompletely parabolic systems of partial differential equations. Such systems can be described as a second order Petrovskii parabolic system and a first order hyperbolic system coupled together by terms with first order spatial derivatives. The dependent variables are then of either parabolic or hyperbolic type. Examples are the equations for couple sound and heat flow and the viscous shallow water equations.


Ovarian cancer is the most deadly gynecological cancer. Despite biomedical research advances, medical progress over recent years in early detection, effective treatment and cure rates has been slow. Only one in four women is diagnosed at Stage I of cancer associated with excellent oncological outcome, more than 70% of those with advanced tumors die of the disease. Here we discuss the advances and challenges of '-omics'-based early-detection biomarkers, hyperthermic intraperitoneal chemotherapy (HIPEC) or neoadjuvant treatment in combination with standard cytoreductive surgery for the treatment of advanced disease and the exciting perspectives of miRNAs for a new generation of biomarkers and drugs.


PURPOSE: To obtain the subject formulation by mixing a hardly water-soluble pharmacologically active substance with carbomer, molding the mixture to a granular shape and covering the resultant granules with a dispersed solution containing a water-swelling acrylic polymer and a water-soluble hydroxylated cellulose derivative. CONSTITUTION: The objective covered granule having 0.5-2.5mm (preferably 0.7-1.2mm) diameter is obtained by providing a granule containing 100 pts. of a hardly water-soluble pharmacologically active substance (e.g. nifedipine, spironolactone, griseofulvin or glibenclamide) and at least 20 pts. (preferably 100-300 pts.) of carbomer and covering the resultant granule with a dispersed solution containing 100 pts. of a water-insoluble and water-swelling acrylic polymer and 20-70 pts. (preferably 20-40 pts.) of a water-soluble hydroxylated cellulose derivative. This formulation combinedly has both quick dissolution of the active component and continuous releasability of the active component for about 24hrs. A weight of the covering material is 2-10wt.% of the inside granule. COPYRIGHT: (C)1990,JPO