Purpose: The purpose of this study is to examine the relationship between TQM, Knowledge Management, and Innovation in business organizations, and to develop a conceptual framework based on this relationship to achieve organizational excellence in the service industry. Design/methodology/approach: The study is based on an extensive literature review on TQM, Knowledge management, and Innovation and their relationships. Based on the review of available literature, a framework is developed to conceptualize this relation in context to the service industry. Findings: The findings of the study show that there is a positive relationship between TQM, Knowledge Management, and Innovation. TQM and Knowledge Management have a reciprocal relationship, which compliments each other, and both lead to Innovation. Finally, a conceptual framework is proposed, which if implemented would enable organizations to achieve organizational excellence. Research limitations/implications: The study is based on the review of available literature and involved service industries in its scope. Practical implications: This study will be very useful for the researchers working in TQM, Knowledge Management, and Innovation. The proposed framework will enable researchers to understand the relationship between all three dimensions and carry out future research based on this study. The study will also help the practitioners to understand the relationship among these areas and how to interlink and apply these within their firms to achieve organizational excellence. Originality/value: The study shows that several studies are carried out in examining the relationship between TQM & Knowledge Management and TQM & Innovation. But there is a research papers, articles, book chapters, reports, and conference proceedings related to TQM. The databases such as research gate, google scholar, and Scopus were referred to search the papers. This study considers a review of published studies on TQM, KM, and Innovation mainly during the year 2000-2021. For this study, the authors have referred to highly reputed international refereed journals and well-known publishers worldwide such as Elsevier, Emerald, Springer, Wiley, Sage, and T&F. Several keywords were used to search the relevant studies, starting with TQM, Knowledge Management, Innovation, TQM in service sector, TQM and KM, TQM and Innovation, KM and Innovation, TQM and Organizational excellence. Later, the searching process were narrowed down using the following keywords: TQM and KM in service organization, TQM and Innovation in service organization, KM and Innovation in service organization, TQM and Organizational excellence in service sector etc. Based on the mentioned search process, all the relevant studies that were under the scope and published only in the academic journals and books are included in the present study. and Innovation especially in the service sector. The study will help the practitioners to understand the relationship among these areas and how to interlink and apply these within the service firms to achieve organizational excellence. This study will help the researchers to understand the present state of research in TQM, KM, and Innovation in the service industry, and will facilitate future studies by highlighting the important issues. The proposed framework will enable researchers to understand the relationship between all three dimensions and carry out future research based on this study to test the findings through empirical study. The study shows that several studies are carried out in investigating the relationship between TQM & Knowledge Management and TQM & Innovation, but there is a dearth of study that covers all three aspects (TQM, Knowledge Management, and Innovation) together under one umbrella and provides a comprehensive framework to achieve organizational excellence in the service industry based on their relationships. Thus, the present study seeks to bridge this gap in the literature.


A 2-year-old boy presented with fever, dry cough and dyspnoea for 3 days. Breath sounds were absent and thoracic percussion revealed dullness in the lower two-thirds of the left hemithorax. A chest x-ray showed almost complete opacification of these areas (figure 1). The boy was successfully treated with antibiotics for lower airways infection but tachypnoea persisted and the x-ray showed no change after 6 weeks. A CT scan was performed and showed a heterogeneous mass in the anterior mediastinum, predominantly on the left side, occupying most of the left hemithorax. This lesion showed areas of lower attenuation interspersed with areas of soft tissue attenuation (figure 2). The possibility of …


(57) ABSTRACT (21) Appl. No.: 14/748,310 A computer implemented method of performing data com pression includes applying, with a computing device, a hash function to a selected part of a character string to calculate a (22) Filed: Jun. 24, 2015 hash value; searching, using the hash value, through entries in a bucket chain having the hash value previously registered in O O a hash table, and finding a longest matching character string; Related U.S. Application Data acquiring, an index indicating that a longest matching char (63) Continuation of application No. 14/640.317, filed on acter string cannot be found in the search through the entries Mar. 6, 2015. and thus the search operation is wasted; and Switching the hash function to a different hash function for expanding the (30) Foreign Application Priority Data selected part of the character string, without reconstructing the hash table, when the index exceeds a predetermined Mar. 25, 2014 (JP) ................................. 2014-061524 threshold.


The countryside debts issues constrain the development of the rural collective economy and public welfare.If which would not be conscientiously studied and solved,will erode the reform results of taxes and fees,and even endanger the stable environment of rural society.In This paper,based on the analysis of village debts in one county level city,puts forward the method of establishing the debt redemptation funds,strengthening the system construction,standardizing the village-level organization for borrowing and lending activities in preventing the new bad loans to develop the production,increase the income,save the expenditures and difuse the rural debts by speeding the research and stipulation of the system for solving the village-level debt problems.


The hydroxycarbonyl compound [IrCl2(CO2H)(CO)(PMe2Ph)2](1), formed by the rapid reaction of water with the dicarbonyl cation [IrCl2(CO)2(PMe2Ph)2]+, behaves both as an acid and as a base. The base-catalysed decarboxylation to give [Ir(H)Cl2(CO)(PMe2Ph)2] occurs via the compound [IrCl(CO)(PMe2Ph)2], but low-temperature 31P and 1H n.m.r. experiments have failed to identify any intermediate such as [IrCl2(CO2)(CO)(PMe2Ph)2]– or [IrCl(CO2)(CO)(PMe2Ph)2]. The decarboxylation of such species very rapidly follows deprotonation of the hydroxycarbonyl even at –90 °C. Treatment of (1) with HBF4·Et2O leads to dehydroxylation with no observable intermediates whereas CF3CO2H reacts initially to give a new species which only gives [IrCl2(CO)2(PMe2Ph)2]+ with an excess of acid present. This cation exists in solution in two forms. Acetic acid, in contrast, leads to decarboxylation.


Differential absorption and harmonic detection techniques are always used to eliminate the intensity fluctuation and optical path interference. However, the cross-talk of gases is not eliminated. For this problem, a correlation spectroscopy method is proposed. In this paper, we analyze the theory of the system in detail. A method for methane gas sensing using a 1.6um LED as a light source is demonstrated based on the analysis of the near infrared spectral absorption of methane as well as the factors such as compatibility with the transmission characteristics of silica optical fiber and the price. The experiment result is shown and proves that the proposed method is practical for both theory and experiment within the error. The repeatability and stability are well. The method inherits the excellence of the traditional correlation spectroscopy, which has high selective characteristics. It can eliminate cross-talk of carbon dioxide etc. Then the sensitivity of the methane detection is enhanced. The system can be used to detect other gases by changing source, so it is general.


Due to the low machinability of titanium alloys, which have been increasingly applied in medical and aerospace industries, several studies have been carried out focusing on the improvement of tool life in machining processes that involve such class of material. Aiming at contributing to the technological investigations and at expanding the knowledge on the phenomena involved in the tool-workpiece contact, this work presents tool wear results and a tribological analysis of the application of cemented tungsten carbide cutting inserts with different roughness characteristics in the edge and flank face as well as grinding marks (grooves) in the rake face in distinct directions. The inserts were prepared by plunge-face grinding and used in turning of a beta-titanium alloy (Ti-15Mo). Results showed that the insert with lower surface and edge roughness and with grooves in the rake face perpendicular to chip flow direction led to the lowest final flank wear value when the tool life criterion was achieved. Higher flank wear values were obtained for the rougher inserts, due to the greater edge chipping produced in grinding.


Photonic crystal (PhCs) has versatile properties with potential to enhance solar cell application. Nanoparticles of poly (methyl methacrylate) (PMMA) have been successfully prepared by green-chemistry approach where no surfactant, cross linking agent and solvent was involved. Introducing of acid hydrolysed TEOS in PhCs boost of numerous fascinating approaches to the enhancement PhCs backbone. Incorporated of metal complex such as zinc(II) complexes were prepared by refluxing in PhCs improved characteristic of solar cells application because of high photocatalytic activity. The experimental results suggest that involving localised surface plasmon resonance (LSPR) properties from excellent plasmonic nanoparticles such gold, silver or the alloy (gold and silver) would enhanced light trapping performance as expressed by properties. The composite inverse photonic crystal was characterised by using FTIR and SEM-EDS.


Abstract. Let ~ := R~. "Ilm following are known: two r/a-sets of power ~ are isomorphic. Let c~ > 0. Two ordered divisible Abelian groups that are r/a-sets of power n are isomorphic, two real closed fields that are r/a-sets of power ~ are isomorphic. The following is shown: (1) there exist 2 ~ nonisomorphic ordered Abelian groups (respectively ordered fields) that are ~Ta-sets of power n; (2) there exist 2 ~ nonisomorphic ordered divisible Abelian groups (respectively real closed fields) of power n all having the same order type; (3) there exist 2 nonisomorphic ordered divisible Abellan groups (respectively real closed fields) that are ~7,~-sets having the same order type.


Background Long-term physical conditions (LTCs) consume the largest share of healthcare budgets. Although common mental disorders (CMDs) and LTCs often co-occur, the potential impact of improved mental health treatment on severe disability and hospital admissions for physical health problems remains unknown. Method A cross-sectional study of 7403 adults aged 16–95 years living in private households in England was performed. LTCs were ascertained by prompted self-report. CMDs were ascertained by structured clinical interview. Disability was assessed using questions about problems with activities of daily living. Population impact and potential preventive gain were estimated using population-attributable fraction (PAF), and conservative estimates were obtained using 'treated non-cases' as the reference group. Results Of the respondents, 20.7% reported at least one LTC. The prevalence of CMDs increased with the number of LTCs, but over two-thirds (71.2%) of CMD cases in people with LTCs were untreated. Statistically significant PAFs were found for CMDs and recent hospital admission [13.5%, 95% confidence intervals (CI) 6.6–20.0] and severe disability (31.3%, 95% CI 27.1–35.2) after adjusting for LTCs and other confounders. Only the latter remained significant when using the most conservative estimate of PAF (21.8%, 95% CI 14.0–28.9), and this was reduced only slightly when considering only participants with LTCs (18.5%, 95% CI 7.9–27.9). Conclusions Better treatments for CMDs in people with LTCs could achieve almost the same population health gain in terms of reducing severe disability as those targeted at the entire population. Interventions to reduce the prevalence of CMDs among people with LTCs should be part of routine medical care.


Simple Summary One of the great advantages of serum biomarkers is that they can be easily obtained in the form of a liquid biopsy of the patient's blood, which is minimally invasive and allows for repeatable measurements. In particular, molecular biomarkers from signaling pathways provide information on tumor characteristics and heterogeneous molecular profiles and enable us to predict prognosis and develop a rationale for therapeutic strategies. The erythroblastic leukemia viral oncogene homolog (ERBB) family has been implicated in hepatocarcinogenesis and is associated with a worse prognosis in hepatocellular carcinoma (HCC). However, its role as a serum biomarker has not been fully evaluated. In the present study, we revealed that serum ERBB2 and neuregulin 4 (NGR4) are independent prognostic factors for survival and tumor recurrence and suggested a possible synergistic effect between these two prognostic factors. Our study could provide predictive biomarkers for evaluating HCC prognosis and monitoring treatment response in patients with HCC. Abstract Although the roles of erythroblastic leukemia viral oncogene homolog 2 (ERBB2), neuregulin 4 (NRG4), and mitogen-inducible gene 6 (MIG6) in epidermal growth factor receptor signaling in hepatocellular carcinoma (HCC) and other malignancies have been previously investigated, the prognostic value of their serum levels in HCC remains undetermined. In the present study, correlations between serum levels and tumor characteristics, overall survival, and tumor recurrence were analyzed. Furthermore, the prognostic potential of the serum levels of these biomarkers was evaluated relative to that of alpha-fetoprotein. Both ERBB2 and NRG4 correlated with the Barcelona Clinic Liver Cancer stage, ERBB2 correlated with the tumor-maximal diameter, and NRG4 correlated with a tumor number. Cox proportional hazards regression analysis revealed that ERBB2 (hazard ratio [HR], 2.719; p = 0.007) was an independent prognostic factor for overall survival. Furthermore, ERBB2 (HR, 2.338; p = 0.002) and NRG4 (HR, 431.763; p = 0.001) were independent prognostic factors for tumor recurrence. The products of ERBB2 and NRG4 had a better area under the curve than alpha-fetoprotein for predicting 6-month, 1-year, 3-year, and 5-year mortality. Therefore, these factors could be used to evaluate prognosis and monitor treatment response in patients with HCC.


The application range of communication robots could be widely expanded by the use of an automatic speech recognition (ASR) system with improved robustness for noise and for speakers of different ages. In this paper, we describe an ASR system which can robustly recognize speech by adults and children in noisy environments. We evaluate the ASR system in a communication robot placed in a real noisy environment. Speech is captured using a twelve-element microphone array arranged in the robot chest. To suppress interference and noise and to attenuate reverberation, we implemented a multi-channel system consisting of an outlier-robust generalized sidelobe canceller (RGSC) technique and a feature-space noise suppression using MMSE criteria. Speech activity periods are detected using GMM-based end-point detection (GMM-EPD). Our ASR system has two decoders for adults' and children's speech. The final hypothesis is selected based on posterior probability. We then assign a generalized word posterior probability (GWPP)-based confidence measure to this hypothesis, and if it is higher than a threshold, we transfer it to a subsequent dialog processing module. The performance of each step was evaluated for adults' and children's speech, by adding different levels of real environment noise recorded in a cafeteria. Experimental results indicated that our ASR system could achieve over 80 % word accuracy in 70 dBA noise. Further evaluation of adult speech recorded in a real noisy environment resulted in 73 % word accuracy


As the most pertinent issue in the present context "The growth of Political Islam in Middle East and specially Turkey's position centering it" is very relevant in the arena of international relations. This assignment deals with the socio-political amalgamation in creating the base of growth for political Islam emphasizing the events may it be extremist reason based or rational political aspects emphasizing the contexts of Middle East based Levantine countries and specially the socio-political dilemma of conservative, fundamentalist and on the other hand secular religious or in between extremist and moderate in Turkey. This work covers the gradual growth of Political Islam through causes and aspects of revolution, Muslim brotherhood issue, revolutions of sometimes party (Ba'ath, AKP etc.) or military and conflict of Islamization in countries especially in Turkey centering the Turkish-Kurdish nationalism and ideas.


We now live in a society flooded by increasing volumes of data. These data are being generated by our everyday actions and the plethora of machines and sensors which surround us. This is especially true for the fields of study related to Earth Observation. Over the last few decades, new government policies have dramatically increased the volumes of data available to the general public. This increase in availability gives rise to new opportunities of analyzing and gaining knowledge from publicly available data stores. This paper is intended to show the benefits of combining modular processing description methodologies with a distributed execution environment, in order to facilitate the processing of large Earth Observation data volumes. It will briefly touch upon our proposed solution - in the form of the BigEarth platform - highlighting its main characteristics, functionality and the potential benefits of using it in order to speed up the processing of large Earth Observation data sets. To this end, we will present a set of experiments conducted to demonstrate the capabilities of our system to take advantage of the inherent task-level parallelism, thus shortening the overall task execution time.


This paper discusses Deep Learning (DL) and Transfer Learning (TL) state of the art techniques applied to a binary classification task for change detection in satellite imagery. A blob detection algorithm is applied to a Differential Interferometric Synthetic Aperture Radar (DInSAR) generated displacement map. The blobs are classified as either positive, corresponding to uplift or subsidence, or negative, corresponding to noise. The novel dataset consists of Sentinel-1 DInSAR processed georeferenced images of displacement, phase, coherence and RGB Sentinel-2 optical satellite imagery of the blobs. TL via Feature Extraction (FE) is applied using numerous DL models with weights pretrained on the ImageNet dataset to generate feature maps after removing the last predictive layer. A Logistic Regression classifier is then applied to the features. Fine-Tuning (FT) and Random Initialisation (RI), training from scratch, are also applied to ResNet-50 and EfficientNet B4 architectures. The best performing model (85.76%) is the ResNet-50 using FE. Small ensembles of some models are also investigated. An ensemble of ResNet-50, ResNeXt-50 and EfficientNet B4 has an accuracy of 84.83%. TL via FE with the ResNet-50 has an accuracy of approx. 9% and 8% higher than when using it for TL via FT or RI respectively. The EfficientNet B4 obtained an accuracy of 82.29% for FE, 66.35% for FT and 50.00% (as good as a random guess) for RI.


Management of logistic entities during economic recession implies the process of establishing functional organizational structure of businesses and building linkages with relevant national institutions, which are most optimal methods for providing the necessary support to businesses in terms of finances and human resources needed to fulfill the set objectives in challenging economic conditions. During economic recession, cost management becomes even more important, in terms of the need for cost-cutting, since the highest level of effectiveness in cost management is obtained when cost cutting is coupled by an increase in the quality of business operations.


These studies also confirm the invitro evaluation of some Iranian plants against human pathogen bacteria. In this study, the essential oil of Cuminumcyminum, Saturejahortensis and Trachysperammi obtained by hydro distillation and the minimum inhibitory concentrations were investigated to characterize the antimicrobial activities of this essential oil. The antimicrobial effect of essential oil of Cuminumcyminum, Saturejahortensis and Trachysperammion pathogenic bacteria namely Klebsiella pneumonia, MRSA, Listeria monocytogenes and Staphylococcus aureus were determined using broth micro diluation method. The results show that the highest MIC value was observed of T. ammiessential oil against S.aureus and S.hortensis essential oil against MRSA.


Received June 3, 2015 Accepted December 22, 2015 One of the serious adverse effects of the antithrombotic agents is intracerebral hemorrhage (ICH). We aimed to evaluate whether antithrombotic agents influence the outcome at the time of hospital discharge in patients with acute phase of ICH. Of the 353 patients with acute phase of ICH, 90 (25.5%) had been treated with antithrombotic agents. Modified rankin scale (mRS) at the time of hospital discharge in patients taking antiplatelet plus antithrombotic agents (combined antiplatelet and anticoagulant therapy: Combined) was higher than those taking antiplatelet agents only (single antiplatelet therapy: SAPT) or anticoagulant agents only (single anticoagulant therapy: SACT). Multiple logistic regression analysis showed that male sex [odds ratio (OR), 2.670; 95% confidence interval (CI), 1.115 6.392; P = 0.027)], hemodialysis (OR, 4.165; 95%CI, 1.572-11.033; P = 0.004), Combined (OR, 10.145; 95%CI, 2.520-40.849; P = 0.001), D-dimer > 1.9 μg/mL (OR, 5.271; 95%CI, 2.327-11.942; P < 0.001), NIHSS ≧ 15 (OR, 4.627; 95%CI, 1.888-11.339; P = 0.001) were associated with the death at the time of hospital discharge. This study shows that the onset of ICH taking Combined is associated with an increased risk of death.


A composite material was prepared from epoxy resin as a base material with the reinforcing materials (natural and synthetic styrene butane rubber) with different weight percentages and different results were obtained depending on the added weight percentages of the reinforcing material, and the effect was clear on the values of mechanical properties and thermal conductivity. The values of the hardness, shock and compressive strength increased after the reinforcing process, but the relationship was inverse between the hardness and compressibility with temperature. As for the shock resistance, it increased with an increase in temperature to 55 °C. As for the thermal conductivity, it decreased when adding natural styrene butadiene and increased by only one degree when adding synthetic styrene butadiene. It is noted that the results that appeared when adding natural styrene butadiene rubber as a reinforcement material is better than the reinforcement by means of synthetic styrene butadiene.


The aim of this study was to formulate and evaluate liposomal gel of Diflurasone diacetate for topical application. Liposomes were prepared by using Soya PC and Egg PC by the lipid film hydration method. It was characterized by DSC and Surface morphology of Liposomes by SEM. assessed for particle size, entrapment efficiency, and their effect on in vitro drug release. The Batch B4 containing Soya PC with Cholesterol in 9:1 was found to be optimized .The Stability study of optimized formulation was done as per ICH guidelines. The Optimized liposomes were incorporated into Carbopol gel (2%) and were evaluated for ex vivo drug permeation studies. It was observed that Diflurasone diacetate loaded liposomes bearing hydrogel was more efficient in the treatment of Psoriasis.


Uniform solutions for the nonlinear oscillation part of the Taylor instability problem are obtained. Two matchable solutions are needed to describe the problem fully—one for wavenumbers sufficiently larger than the cutoff (outer solution), and one for wavenumbers near the cutoff (inner solution). A nonlinear cutoff is obtained only after the inner solution is obtained. Singular perturbation methods are used for both the outer and the inner problems.


Known and inferred surficial structural features of the Aleutian Ridge, Terrace, and Trench in the central and western Aleutian arc, Alaska, appear to reflect predominantly tensional strain of diverse orientations. Features on the ridge are inferred to have formed from igneous activity-related tectonism including distension of the surficial skin over rising and spreading epizonal plutons, volcanotectonic subsidence, and rifting; features on the terrace and landward trench wall may have formed from distension of a decoupled surficial skin above a prolongated zone of imbrication and uplift; and those in the trench and on the seaward wall from dynamic loading of the Pacific lithospheric plate by overthrusting and southward migration of the Aleutian tectogene. The plutonism, mbrication, and dynamic loading are interpreted as resulting from a first-order process of crustal foreshortening normal to the arc. This interpretation is consistent with evidence from natural seismicity which indicates predominantly compressional strain across the central and eastern Aleutian arc. Surficial structural features in the eastern Aleutian arc between the continental margin and the volcanic arc appear to reflect directly the first-order compressional strain, whereas the features in the bordering Aleutian Trench are predominantly of tensional origin. Movement vectors for the Pacific plate based on a pole of rotation at lat. 53°N, long. 47°W., indicate normal convergence against the continental margin near Kodiak Island, movement tangential to the arc trend in the vicinity of the Near Islands, and tension oblique to the arc trend in the vicinity of the Commander Islands. If the Aleutian Trench has resulted from crustal foreshortening its presence along the entire arc suggests movement of the Bering Sea plate independent of the Pacific plate. Structural features such as Bowers Ridge in the western Aleutian arc may reflect foreshortening parallel with the arc. Such features may be related to Pacific plate movement, whereas the arc itself there may have resulted from movement of the Bering Sea plate. The eastern Aleutian arc could have resulted from south-to-southeast drift of the Alaskan continental mass hinged to the Canadian mainland along the axis of the Alaska orocline combined with Pacific plate normal convergence. Body forces such as those that might be derived from perturbations of rotational parameters (angular momentum and moments of inertia) of the core-mantle system seem better suited to explain the suggested plate movements than are forces derived from mantle convection. End_of_Article - Last_Page 2467------------


Atrial fibrillation (AF) has been linked to the presence of underlying coronary artery disease (CAD). However, whether the higher burden of CAD observed in AF patients translates into higher burden of myocardial ischemia is unknown. In 87 patients (71% male, mean age 61±10 years) with paroxysmal or persistent AF and without history of CAD, MSCT coronary angiography and stress testing (exercise ECG test or myocardial perfusion imaging) were performed. CAD was classified as obstructive (≥50% luminal narrowing) or not. Stress tests were classified as normal or abnormal. A population of 122 patients without history of AF, similar to the AF group as to age, gender, symptomatic status and pre-test likelihood, served as a control group. Based on MSCT, 17% of AF patients were classified as having no CAD, whereas 43% showed non-obstructive CAD and the remaining 40% had obstructive CAD. A positive stress test was observed in 49% of AF patients with obstructive CAD. Among non-AF patients, 34% were classified as having no CAD, while 41% showed nonobstructive CAD and 25% had obstructive CAD (p = 0.013 compared to AF patients). A positive stress test was observed in 48% of non-AF patients with obstructive CAD. In conclusion, the higher burden of CAD observed in AF patients is not associated to higher burden of myocardial ischemia. Relationship Between Obstructive Coronary Artery Disease and Abnormal Stress Testing in Patients With Paroxysmal or Persistent Atrial Fibrillation 109 INTRODUCTION Atrial fibrillation (AF) has been shown to be an independent risk factor for future coronary artery disease (CAD) events.16 Accordingly, evaluation of AF patients for CAD may potentially be useful, in order to improve their outcome. Multi-slice computed tomography (MSCT) coronary angiography has emerged as an accurate technique for the non-invasive imaging of coronary atherosclerosis.7 In a recent study using MSCT coronary angiography, a higher prevalence of CAD and obstructive CAD was found among patients with paroxysmal or persistent AF, as compared to patients without a history of AF; in addition, a significant independent relation between AF and CAD was observed.8 However, MSCT coronary angiography does not provide information about the hemodynamic consequences of observed coronary lesions;9,10 therefore, whether the higher burden of CAD observed in AF patients is associated also to a higher burden of myocardial ischemia remains to be determined. Accordingly, the aim of the present study was to evaluate the relation between the evidence of coronary atherosclerosis (by means of MSCT coronary angiography) and the presence of abnormal stress testing among patients with paroxysmal or persistent AF and compare findings to patients without a history of AF.


This research was carried out in Riobamba Education Unit, in Chimborazo province, being of great interest the traditional Ecuadorian Dance because they stimulate the psychomotricity, in addition the mental and motor abilities enrich and serve as foundation for the own life for the child and the girls. According to the objectives , the strategies used by the educators for the development of psychomotricity in children were diagnosed, an analysis of the two variables was made, the dependent variable talking in this study of the Psychomotricity in different areas, its importance.
As well as the study of the independent variable in this case the Traditional Ecuadorian Dance, obtaining from its history, classification and importance.
The method used in this research was deductive, analytical, for data collection, as the technique was used the observation sheet, the type of research used was exploratory, documentary, field and applied. After the diagnosis, some findings were identified, it was possible to show that in a large percentage of the children have difficulties in maintaining balance in the execution of movements, as well as difficulties in the tactile perception when performing movements on the floor, because Traditional Ecuadorian dance is not used as a strategy, emphasizing the importance of dance as a playful and complete activity in working the body and mind; Contributing to the integral formation of the children, it allows to identify their roots, an authentic expression and fomenting the folklore as a factor of socialization.
In conclusion we can say that there is success in the level of development of psychomotricity it will allow the child to have a control of the body, for which it is suggested to work with dance activities, this will facilitate their better development.


Background Although growth advantage of certain clones would ultimately translate into a clinically visible disease progression, radiological imaging does not reflect clonal evolution at molecular level. Circulating tumor DNA (ctDNA), validated as a tool for mutation detection in lung cancer, could reflect dynamic molecular changes. We evaluated the utility of ctDNA as a predictive and a prognostic marker in disease monitoring of advanced non-small cell lung cancer (NSCLC) patients. Methods This is a multicenter prospective cohort study. We performed capture-based ultra-deep sequencing on longitudinal plasma samples utilizing a panel consisting of 168 NSCLC-related genes on 949 advanced NSCLC patients with driver mutations to monitor treatment responses and disease progression. The correlations between ctDNA and progression-free survival (PFS)/overall survival (OS) were performed on 248 patients undergoing various treatments with the minimum of 2 ctDNA tests. Results The results of this study revealed that higher ctDNA abundance (P=0.012) and mutation count (P=8.5×10−4) at baseline are associated with shorter OS. We also found that patients with ctDNA clearance, not just driver mutation clearance, at any point during the course of treatment were associated with longer PFS (P=2.2×10−16, HR 0.28) and OS (P=4.5×10−6, HR 0.19) regardless of type of treatment and evaluation schedule. Conclusions This prospective real-world study shows that ctDNA clearance during treatment may serve as predictive and prognostic marker across a wide spectrum of treatment regimens.


THE Berlin Festival scored an undoubted success with its new venture. Those who attended the weekend of events (which centred on the exhibition areas and concert hall of the magnificent new State Library) were obviously well pleased. But since the events were to some extent aimed at younger listeners, it was a pity that they took place at a time when Berlin's student population was still on vacation. For that reason, and also because both composers were new to Berlin, the concerts attracted smaller and more specialized audiences than they deserved. For both composers, the invitation to pilot a new scheme such as this was certainly an honour, though the task of breaking the ice was hardly grateful. The lessons learnt from the weekend are positive as well as negative, and will doubtless assist the planning of next year's events in the same series. Neither Schwertsik nor Gruber can be dissociated from the history of the Salon Concerts and the 'MOB art & tone ART' Ensemble which they founded (in the Vienna of the 1960's) in collaboration with Otto M. Zykan, the pianist and composer. Zykan was always the most eloquent spokesman of the group. With characteristic consistency, it was he who concentrated on speech-compositions. Although his refusal to make music in a conventional avant-garde sense eventually committed him to forms of non-music which may have turned out to be a blind alley, his experiments had an important bearing on the very different work of his two composer-colleagues, and should therefore have been represented in Berlin. Not only would that have set in relief the more traditional music-making of Schwertsik and Gruber, but a polemical opening by Zykan would surely have been the most appropriate for a weekend which had been advertised under the slogan 'No New Viennese School'. Unfortunately, the exigencies of programmeplanning did not leave room for Zykan.


This paper proposes an adaptive super-twisting algorithm based sliding-mode observer (STA-SMO) for surface-mounted permanent magnet synchronous machine (PMSM) sensorless control, in which voltage source inverter (VSI) nonlinearity is taken into consideration. An adaptive algorithm for online tuning the sliding-mode coefficients of STA-SMO is proposed based on the existing stable conditions. Thus, position estimation error can be reduced by the proposed adaptive algorithm in wide-speed range. Furthermore, voltage distortion due to VSI nonlinearity is online compensated to improve the accuracy of PMSM model. Because mismatch between reference and actual voltage due to VSI nonlinearity may bring large rotor position and speed estimation error, especially in low-speed range where distorted voltages may become dominant compared to actual voltages. Thus, a STA-SMO with adaptive sliding-mode coefficients and accurate voltage value could be obtained. Finally, the effectiveness of the proposed adaptive STA-SMO with online VSI nonlinearity compensation is verified on a surface-mounted PMSM by experiments.


PurposeWith the advent of ChatGPT, a sophisticated generative artificial intelligence (AI) tool, maintaining academic integrity in all educational settings has recently become a challenge for educators. This paper discusses a method and necessary strategies to confront this challenge.Design/methodology/approachIn this study, a language model was defined to achieve high accuracy in distinguishing ChatGPT-generated essays from human written essays with a particular focus on "not falsely" classifying genuinely human-written essays as AI-generated (Negative).FindingsVia support vector machine (SVM) algorithm 100% accuracy was recorded for identifying human generated essays. The author discussed the key use of Recall and F2 score for measuring classification performance and the importance of eliminating False Negatives and making sure that no actual human generated essays are incorrectly classified as AI generated. The results of the proposed model's classification algorithms were compared to those of AI-generated text detection software developed by OpenAI, GPTZero and Copyleaks.Practical implicationsAI-generated essays submitted by students can be detected by teachers and educational designers using the proposed language model and machine learning (ML) classifier at a high accuracy. Human (student)-generated essays can and must be correctly identified with 100% accuracy even if the overall classification accuracy performance is slightly reduced.Originality/valueThis is the first and only study that used an n-gram bag-of-words (BOWs) discrepancy language model as input for a classifier to make such prediction and compared the classification results of other AI-generated text detection software in an empirical way.


This article assesses the social place of greek and latin classics in early twentieth France, when these subjetcs were at the core of a fast and controversial educational reform. It will be emphasized the last phase of Marcel Proust's literary and critic production (specially Contre Sainte-Beuve and A la Recherche du Temps Perdu).


A method of imparting resistance to high temperature degradation resistance to a component associated with an internal combustion engine, said part of the surface, it is coated with a metal slurry comprising a Co-based metal component, a binder and a solvent; and the Co-based metal component the by sintering, is a substantially continuous Co-based alloy coating method comprising forming on the surface of the body. An internal combustion engine component comprising a Co-based alloy coating on the metal substrate, the Co-based alloy coating is an internal combustion engine component having a thickness of about 100 to about 1000 microns.


A BSTRACT . The purpose of this paper is to prove pointwise inequalities and to establish the boundedness on weighted L p spaces for pseudo-differential operators T a defined by the symbol a ∈ S m̺,δ with 0 ≤ ̺ ≤ 1 , 0 ≤ δ < 1 . Firstly, we prove that if m ≤ − n (1 − ̺ ) / 2 , then ( T a u ) ♯ ( x ) . M ( | u | 2 ) 1 / 2 ( x ) for all x ∈ R n and all Schwartz function u . Secondly, it is shown that if 1 ≤ r ≤ 2 and m ≤ − nr (1 − ̺ ) , then for any ω belongs to the class of Muckenhoupt weights A p/r with r < p < ∞ , these operators are bounded on L pω . Moreover, these results are sharp on the bound of m .


Turkey, a country affected by natural disasters is natural disasters such as flooding and landslides are seen frequently. Floods and landslides are one of the common natural disasters in Turkey. The use of GIS-based spatial statistical analysis in disaster studies has increased in recent years. From this point, it is essential to examine the spatial distribution of disasters to prevent and mitigate disasters. In this study, flood and landslides disasters that occurred between 1960 and 2018 in Turkey is aimed to determine the spatial analysis using spatial autocorrelation methods. The problem of how these two disaster types distribute is the most pressing thing in disaster risk assessment. Data set was taken from the Disaster Knowledge Base system (TABB) of the Republic Of Turkey Ministry Of Interior Disaster And Emergency Management Presidency. Various indices related to spatial autocorrelation were classified and also they were explained mathematically. Spatial autocorrelation indices such as Moran's I, Getis Ord G, and Geary C were used to determine whether there were clustering in the data set. The rates of flood and landslide in the provinces showing clustering and their distribution are examined and also Flood and landslide distributions in clustered provinces were examined, tested with indices and compared and the results are presented in detail.


and New Orleans has a large reptile population embracing a wide variety of species. A casual study of the snakes of the region was started about ten years ago and from this has developed a sizable backyard collection comprising about 150 specimens each summer, most of which are released or given away as cold weather approaches. Certain miscellaneous observations accumulated during the past several years seem worthy of record. Twenty-one species of snakes have been captured within a radius of 10 miles of Gramercy. Those which are extremely common are: Farancia abacura reinwardtii Natrix erythrogaster transversa Heterodon contortrix Natrix r. rhombifera Lampropeltis getulus holbrookii Natrix sipedon confluens Natrix cyclopion cyclopion Thamnophis sirtalis sirtalis


Glycogen synthase kinase 3β (GSK-3β) is a widely investigated molecular target for numerous diseases including Alzheimer's disease, cancer and diabetes mellitus. The present study was aimed to discover new scaffolds for GSK-3β inhibition, through protein-structure guided virtual screening approach. With the availability of large number of GSK-3β crystal structures with varying degree of RMSD in protein backbone and RMSF in side chain geometry; herein appropriate crystal structures were selected based on the characteristic ROC curve and percentage enrichment of actives. The validated docking protocol was employed to screen a library of 50,000 small molecules using molecular docking and binding affinity calculations. Based on the GLIDE docking score, Prime MMGB/SA binding affinity and interaction pattern analysis, the top 50 ligands were selected for GSK-3β inhibition. (Z)-2-(3-chlorobenzylidene)-3,4-dihydro-N-(2-methoxyethyl)-3-oxo-2Hbenzo[b][1,4]oxazine-6-carboxamide (F389-0663, 7) was identified as a potent inhibitor of GSK-3 with an IC50 value of 1.6 μM. Further, GSK-3 inhibition activity was then investigated in cell-based assay. The treatment of neuroblastoma N2a cells with 12.5 μM of F389-0663 resulted in the significant increase in GSK-3 Ser9 levels, which is indicative of the GSK-3 inhibitory activity of a compound. The molecular dynamic simulations were carried out to understand the interactions of F389-0663 with GSK-3β protein. A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. Introduction Glycogen synthase kinase 3 (GSK-3α, GSK-3β, and GSK-3β2) signaling is a critical regulator of cell division, cell survival, cell proliferation, stem-cell renewal and differentiation, apoptosis, circadian rhythm, transcription, and insulin action (1-3). GSK-3β is a highly conserved serine/threonine protein kinase consisting of 482 amino acids (46.7 kDa). It regulates cell metabolism in mitochondria, neuronal plasticity in brain cells, and apoptosis in carcinogenesis. It phosphorylates wide variety of endogenous substrates in multiple manners including those having canonical phosphorylation sequence–SXXXS. These sequences generally comprises two serine residues separated by three residues such as present in glycogen synthase, amyloid precursor protein, presenillins, cyclin D1, cyclin E, tau protein and transcriptional factors of p53 and β-catenin. GSK-3β is the major contributor for hyperphosphorylation of tau protein in the pathological cells of the Alzheimer disease (AD) brain (4, 5). Therefore, it is considered as a key target in Alzheimer's disease and also for several other diseases (6-14). The success of virtual screening approach for identification of potential GSK-3 inhibitors has been demonstrated by numerous reports (15-20). Cho's group (2009) (15) performed virtual screening of in-house thiazolidine-dione based synthetic library by SurflexDock method. They identified 1,2,4-thiadiazolidine-3,5-dione KRM-191 (1) possessing GSK-3 inhibition with IC50 value of 0.46 μM. Pae's group in 2008 (17) identified another 1,2,4-thiadiazolidine-3,5-dione 2 (GSK-3: IC50 =1.56 μM) through 3D-common pharmacophore and docking approaches. Similarly, El Sayed's group (2010) (16) reported identification of three different chemical class of hits viz. 9Hpurine analog 3, pyrido[2,3-d]pyrimidine 4 and 2-anilino-1,3,4-oxadiazole 5 as potent GSK-3 inhibitors (GSK-3: IC50 values of 10.8, 17 and 138 nM, respectively) by virtual screening of various databases. Recently, Ombrato et. al. (2015) (21) have identified indazole derivative 6 as potent GSK3 inhibitor with IC50 of 350 nM by virtual screening of in-house Angelini library. Apart from these successful reports, there exist several other reports on virtual screening of large databases for identification of potential GSK-3 inhibitors, wherein the experimental validation of hits has not been performed (18, 20, 22-25). A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. In the present paper, we report virtual screening of commercially purchased small molecule repository of 50,000 drug-like compounds using validated docking protocol for identification of potential GSK-3 inhibitors. The docking protocol was validated by calculation of percentage enrichment factor (% EF) from ROC curve. The identified GSK-3 inhibitor hits were validated by GSK-3 inhibition screening in in-vitro cell-free as well as cell-based assays. The virtual screening efforts led to the identification of benzo[b][1,4]oxazine class of GSK-3 inhibitor 7 with IC50 value of 1.6 μM. The molecular dynamics (MD) simulation of the best inhibitor 7 was carried out to understand the interaction pattern of the inhibitor in enzyme active site. Further, F389-0633 selectivity to GSK-3β in contrast to homologous CDKs was deduced using interaction pattern analysis. The chemical structures of GSK-3β inhibitors identified by virtual screening strategy are shown in Figure 1. Experimental section All computations were carried out on HPZ840 ZD 2.3 1TB 8G W8.1P64 DG W7P64 WS using Linux operating system. GLIDE 9.0 module of Schrodinger suite was used to calculate percentage enrichment factor as well as for screening the in-house commercially available compound collection from ChemDiv and ChemBridge databases. The detailed experimental protocol for structure-based virtual screening and MD simulation of identified lead is provided in supporting information. The cell-free GSK-3β screening was carried out at international center for kinase Profiling, University of Dundee (UK) on commercial basis. The effect of F389-0663 (7) on GSK-3βSer 9 phosphorylation in neuroblastoma cells was then studied. The detailed experimental protocols are provided in supporting information (Methods S1). Results and Discussion With the aim to identify potential scaffolds for GSK-3 inhibition, we planned to carry out virtual high throughput screening (vHTS) of commercially purchased small molecules collection of 50,000 (drug-like compounds purchased from ChemBridge and ChemDiv). In most of the cocrystallized GSK-3β crystal structures, various inhibitors mimic the polar interactions between Asp133, Val135, Gln185 of enzyme and substrate ATP. Furthermore, these crystallized inhibitors A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. also show interactions at the secondary binding site where they induce a certain degree of conformational change in the structure of GSK-3β. Due to these conformational changes, RMSD in backbone and RMSF in side chain geometry was different in various GSK-3β crystal structures. Therefore, it was essential to scrutinize the available X-ray crystal structures of GSK-3β (almost >60) for such structural and conformational variations (18). The detailed analysis of X-ray crystal structures of GSK-3β revealed that Gln185 and Thr138 residues of secondary binding site are involved in the ligand-induced conformation changes. Furthermore, it is noteworthy to mention that the side chain of Gln185 adopts two types of conformations: (a) gauche conformation, where Gln185 interacts with inhibitors via water mediated H-bonding, or (b) anti-conformation, where the side chain of Gln185 directly interacts with the ligand via H-bonding (18, 26). Since the geometry and flexibility of the binding site have great impact on the % enrichment of the inhibitors in vHTS; it is highly essential to consider these factors in order to get significant enrichment of actives (22). However, in contrast to this, if we incorporate these factors in terms of ligand induced fit mechanism or MD simulations, the speed and cost of screening gets compromised (27). Thus, we selected two types of GSK-3β crystal structures 1UV5 (Gln185 in anti-conformation) and 1Q5K (Gln185 in gauche-conformation) for percentage enrichment and Receiver Operating Curve (ROC) calculation based on the superior inhibitor drug likeliness and crystallographic data as mentioned in the supporting information (Table S2-S3). Validation of Virtual Screening Protocol. The ROC graph for both proteins (1UV5 and 1Q5K) was built between true positive rate (sensitivity) on y-axis and false positive rate (1-specificity) on xaxis. This graph reveals the prospect of a randomly selected active compound, ranking it higher over a randomly selected decoy molecule. The ROC area under curve values for docking using Glide SP for crystal structures 1UV5 and 1Q5K were found to be 0.58 and 0.76. This demonstrated that a randomly chosen actives had a higher score than a randomly chosen decoy/inactive. The ROC curves for 1UV5 and 1Q5K are shown in Figure 2. The active dataset of GSK-3β inhibitors is provided in supporting information (Table S1). A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. The obtained ROC value of 0.76 for docking 1Q5K seemed to be reasonable for virtual screening. The combined dataset of decoys and actives was also analysed wherein a very high enrichment of actives was observed using 1Q5K (Table S2-S3). Another parameter, BEDROC (α = 160.9) value, which focuses on the selectivity was analyzed and was found to show comparatively high results for 1Q5K than 1UV5. The BEDROC value for 1Q5K and 1UV5 was 0.243 and 0.0102, respectively. The enrichment factor of 1Q5K and 1UV5 (EF = 39.1 and 34.8% respectively) suggests that the protocol is suitable to fish-out potential GSK-3β inhibitors from a large compound collections. Therefore, based on the validation results, 1Q5K was selected for virtual screening (Table S2-S3). Virtual screening and selection of putative ligands. The 50,000 in-house commercially purchased library was filtered for Lipinski rule violators, reactive functional groups and pan assay interference compounds (PAINS) before screening by docking protocols which includes vHTS (virtual High Throughput Screening), SP (Supra Precision) and XP (Extra Precision


Knowledge of the effects of neutron absorbers on the criticality of uranium-plutonium systems is necessary to better establish criticality safety programs. These data are needed in setting criticality safety specifications for storage, processing, and shipping of fissile materials where it is desired to handle quantities with safety and efficiency. These data are also needed for validating calculational techniques and cross-section sets. Aqueous solutions of the nitrates of uranium and plutonium were used in these experiments to determine the effect of neutron absorbers on criticality. In some experiments, UO/sub 2/ and PuO/sub 2/ rods were latticed in the solutions to which various amounts of gadolinium and a gadolinium-boron mixture were added. Critical dimensions were measured of homogeneous mixtures of the solutions with varying amounts of gadolinium and gadolinium-boron added. The effect of boron-blass Raschig rings on the criticality of the solutions was also determined. Plutonium comprised 30 wt% of the uranium-plutonium component of the solution.


In this work we present two finite-difference schemes for solving this equation with one initial and boundary conditions. We study stability and consistency of these methods. Two methods are explicit and they approximates the solutions of the wave equation with consistency of order O { (∆t), (∆x) } , for examining the accuracy of the results , we compare the results with the solution obtained by the methods of separation of variable, also a numerical example for each methods is presented and compared with each other. Finally, the graphs of the error have been plotted to show the methods work with high accuracy.


The aim of our work was to evaluate the incidence of intra-abdominal hypertension and related hypoperfusion of splanchnic organs following major surgeries. The study included patients undergoing elective intra-abdominal surgery with scheduled surgery duration longer than two hours. The postoperative measurement of intra-abdominal pressure (IAP), gastric tonometry (GT), and blood gases was conducted at times T0, T1, T6, T12, T18, and T24. Also, intra-abdominal perfusion pressure (APP) and CO2 gap were calculated. Indocyanine green clearance (ICG-PDR) was measured non-invasively at times T1 and T6. The study included 13 patients (9 men and 4 women) with an average age of 69 (35; 78), who underwent non-complicated surgeries in combined anaesthesia. Postoperative analgesia was provided by means of epidural catheter. The average IAP upon intensive care reception was 8 (1; 18) mm hg, and in the course of the study it did not show any significant change. Only three patients (23 %) were recorded as having IAP higher than 12 mm hg at least once in the course of the study. IAP higher than 25 mm hg was not recorded at all. The average APP at time T0 was 87 (62; 105) mm hg, and in the course of the study it showed a significant decrease (p < 0.001). The average CO gap was –0.1 (–1; 2.9) kPa and it showed no significant change. Only two patients were recorded as having pathological value of ICG-PDR lower than 18 %/min. All patients underwent intensive care treatment without any significant complications, with the exception of a patient who died of malignant arrhythmia on the fourth postoperational day. According to our experience, significant rise in IAP following major intra-abdominal surgeries is very rare. Similarly rare is hypoperfusion of gastric mucosa and liver hypofunction.


The general situation of integrated hydraulic pump-motor is introduced,and the theoretical analysis of the power balance is done.The experimental results show that the theory of power balance on integrated hydraulic pump-motor is correct.The thermal calculation for comprehensive transmission system can be carried out based on the principles.


This article offers a social history of funfairs and arcades in mid-20th-century urban England. Critiquing existing histories of games for often neglecting players and the specific locales in which games are played, it draws on both new cinema history and cultural studies' conception of "radical contextualism" to outline what the article describes as a game's ludosity. Ludosity, the article proposes, is the condition or quality of game partcipation as shaped by a range of agents, institutions, and contexts. Utilizing mass observation records, it offers a detailed analysis of the ways in which social interactions influenced ludic experiences of pinball tables and crane machines and posits that games history needs to center players in order to fully conceptualize games in history.


RECENTLY, 14 white male patients were admitted to this hospital with myocardial failure accompanied by pericardial effusion. The favorite beverage of each was beer. We had not previously encountered pericardial effusion in "alcoholic myocardopathy." 1,2 The large globular heart shadow seen on x-ray film in myocardopathies suggests pericardial fluid, 2-4 but its presence has been rarely documented. 3,4 It is the purpose of this report to emphasize this feature which was present in 14 patients. These men presented a slightly different picture from others with myocardopathy. 5,6 The patients, mostly middle-aged, usually lived alone, ate sporadically, often worked as part-time bartenders, and admitted to drinking or were reputed to drink beer continuously during the waking hours. Edema was frequently massive, and often preceded dyspnea. The latter was gradual in onset and often did not prompt hospitalization until it was very distressing and orthopnea intervened. A plethoric, cyanotic appearance was common. Neck veins were markedly


This paper introduces the basic principles of laserdraw and dispatch-typesetting machines, analyzes the shortcomings of traditional dispatch-typesetting system, and proposed new design program based on the new dispatch-typesetting system based on USB2.0 and FPGA. At the same time, this paper discusses the hardware and software implementation techniques, and in-depth analysis on one of the key modules. While dispatch-typesetting system reduced costs dramatically, it is improving reliability, and it can meet the actual application requirements.


The IR, 1H and 13C NMR spectra of six esters of 1-aryl-4-methyl-3- and 5-pyrazolecarboxylic acids are reported. On the basis of their spectra the 3- or 5-position of the substituent in such structural isomeric pairs can be established without recourse to the spectrum of the other member of the pair. The spectral data also give information on the conformation, which depends on the relative position and size of the hetero ring substituents.


El Guindi and Read criticize our (Kushnick and Fessler 2011) exploration of Westermarckian phenomena on the grounds that (1) evidence in support of the Westermarck hypothesis (WH) is weak and (2) our characterization of Karo marriage preferences is misguided. Their critique, however, suffers from a selective use of the literature, a misconstrual of the hypothesis at issue, and factual errors. El Guindi and Read's first position presumes that human psychology lacks evolved inbreeding-avoidance mechanisms—in their words, "Why should there be a natural aversion among siblings?" While this was a plausible question when Westermarck's contemporaries challenged him over a century ago, it is an astounding position to adopt today. Voluminous evidence documents such mechanisms in other species (e.g., Pusey 2004), findings paralleled by psychological research in humans independent of the natural experiments that El Guindi and Read problematize (Lieberman et al. 2003, 2007; Fessler and Navarette 2004). Moreover, the evidence regarding natural experiments is far less equivocal than El Guindi and Read suggest. Humans' detection of biological relatedness relies on a hierarchy of cues (Lieberman et al. 2007). When natural experiments are revisited in light of this (Lieberman 2009; Lieberman and Lobel 2012), the evidence in favor of the WH is substantially strengthened—indeed, contrary to the impression created by El Guindi and Read's out-of-context quotation, Rantala and Marcinkowska (2011) made exactly this point in their review. El Guindi and Read discuss the prevalence of cousin marriage in Qatar, and point to Henrich and Henrich's (2007) work among Chaldeans, as evidence of "the desirability of marriage among close kin." However, the authors are (1) conflating a cultural preference for cousin marriage with the subjective experience of sexual attraction and (2) failing to grasp the role of cosocialization in the WH. There is nothing new in the observation that norms for cousin marriage are common—indeed, it was precisely this that motivated Westermarck's original work, as the conflict he observed was between a prescription for cousin marriage and a subjective aversion resulting from cosocialization. Correspondingly, al-


A new species belonging to the genus Lesteva Latreille is described under the name of Lesteva ochra, sp. nov. It is collected from Zhejiang Province, China. The major characters are illustrated.


The identification of indicators of the indirect effects of fishing is often an issue for fisheries management, particularly if just commercial catch data are available. Complex, intermediate, and simplified qualitative models were produced for a fishery case study off Western Australia to identify potential indicators of ecosystem change attributable to western rock lobster (Panulirus cygnus) extraction and bait input. Models of intermediate complexity were used to identify indicators because they produced the least aggregation error. Structural uncertainty was considered through a series of structurally different intermediate models. These alternate models consistently predicted that extraction of rock lobster may positively impact small fish of low economic value, such as old wife (Enoplosus armatus), footballer sweep (Neatypus obliquus), and king wrasse (Coris auricularis). These small fish were therefore identified as potential indicators of the effects of rock lobster extraction. Small crustaceans (amphipods and isopods) also displayed positive impacts attributable to bait input from the rock lobster fishery and were identified as potential indicators of bait effects. Monitoring of these indicators may aid the detection of ecosystem change caused by the rock lobster fishery.


© 2020 Neurology India, Neurological Society of India | Published by Wolters Kluwer ‐ Medknow I went through with interest the article the article titled "Role of Aspirin in Tuberculous Meningitis: A Systematic Review and Meta‐analysis" published in Neurology India (Neurol India 2019; 67:993‐1002),[1] primarily because of my interest in Systematic Reviews and Meta‐analysis. I must congratulate the authors for their effort despite the known difficulties faced by individual authors in conducting a meta‐analysis when comparing it with group or consortia conducted reviews and meta‐analysis. This communication without going into merits or otherwise of this meta‐analysis is intended at raising some important issues associated with author‐based reviews.


Aims: Depression is known to have an overarching negative impact on the quality of life of afflicted individuals. Mitigation of depression associated adverse outcomes is mostly reliant upon timely diagnosis and decisive intervention. Antidepressants and adjunct drugs constitute the pharmacological modalities for the therapy of depression, in addition to supportive non-pharmacological methods of management. This prospective cross-sectional observational study aims at analyzing the utilization of antidepressants in American Psychiatric Association (APA) categories of depression in a remote North-East Indian teaching hospital. Methods: Patients clinically diagnosed with depression based on Diagnostic and Statistical Manual of Mental Disorders (DSM) and prescribed with antidepressant medication, were included in the study. The data were analyzed based on demographic characteristics, prescribed antidepressant medication and co-prescribed adjunct drugs. Results: A total of 316 patients were included in the study. The SSRI class of antidepressants were prescribed most frequently (89%) followed by TCAs (6%) & SNRIs (4.4%). Escitalopram was the single most frequently prescribed antidepressant (51%) followed by sertraline (23%) & fluoxetine (11.4%). The SSRIs were used most frequently in bipolar disorder (94.7%), followed by depressive episode (89.2%) & mixed anxiety depressive disorder (88.2%). The utilization of SSRIs was more frequent in the ≤ 50 age group (90.3%) and in males (92.5%). Sedatives including benzodiazepines, were used in 78.8% and atypical antipsychotics in 8.9% of the patients. Conclusion: SSRIs are the most frequently used antidepressant class across all categories of depression. Benzodiazepines have been extensively co-prescribed. The pharmacotherapy of depression in this hospital conforms to currently available clinical evidence and treatment guidelines.


Convolutional neural networks (CNNs) haveachieved great success in many applications. Recently, variousFPGA-based accelerators have been proposed to improve theperformance of CNNs. However, current most FPGA-basedmethods use single bit-width selection for all CNN layers, which lead to very low resource utilization efficiency anddifficulty in further performance improvement. In this paper, we propose a new approach utilizing bit-width partitioning ofFPGA DSP resources to improve the performance andresource utilization efficiency of CNN accelerator. Moreover, we use optimization approach to find the optimal allocationplan for DSP resources. On a Xilinx Virtex-7 FPGA, ourdesign approach achieves performance over the state-of-the-artFPGA-based CNN accelerators from 5.48x to 7.25x and by6.21x on average, when we evaluate the popular CNNs.


As Electronic industry is progressing through the decades, electronic products tend to become increasingly complex. One of the major challenges in the industry today is to design products with Electromagnetic Compatibility (EMC) in the given size and cost. In order to ensure a certain product meets global norms related to Electromagnetic Interference (EMI) and EMC there are specific standards which a product has to comply. Such a challenging standard is IEC61000-4-3 which is the International Standard for Radiated, Radio Frequency, and Electromagnetic field immunity test. Radiated immunity is especially demanding in products without a metal body, polycarbonate or other plastics provide no shielding against electromagnetic radiation. Due to constraints in size and cost the PCB design should be optimum so as to provide maximum immunity against radiation. Very low power analog signals are highly susceptible to radiated noise, operational amplifier circuits malfunction if susceptible to radiation. In this research work various improvements done in the PCB design of the operational amplifier section to achieve radiated immunity in a previously non complaint design is shown.


Motivation is a strong tool in the hand of managers and leaders. This tool can only be utilized when the factors that motivate subordinates are known and built into the leadership process. This study investigated the factors that motivate software developers in Nigeria with aid of questionnaires and informal interaction with some Information Technology (IT) professionals. A five point Likert scale ranging from "strongly Agree" to "Undecided" was used to measure the degree of intensity of a respondent's feeling about each item on the questionnaire. It was found that developers were motivated both intrinsically and extrinsically. It was also observed those courtesy, good reward systems, regular training, recognition, tolerance of mistakes and good leadership were high motivators of software developers. Keywords: Software developers, information technology, project managers, Nigeria International Journal of Natural and Applied Sciences , 6(4): 406 - 411, 2010


This article details and analyses the development of European Court of Justice guidelines regarding sanctions provided by Member States to correct infractions of EC law. It will be shown that the contemporary policy of the Court significantly retreats from an early practice of non‐interference with the discretion of national judges to attach domestic remedies for breach of substantive Community measures. Preliminary comments will be made on the possible impact of these developments on the constitutional structure of the Community, and in particular their potential effect on the continuing debate concerning the legitimacy of EC rules.


In this paper, the in-band amplified spontaneous emission (ASE) in the Yb-doped continuous-wave (CW) fiber amplifier operating near 980 nm is experimentally studied for the first time, to the best of our knowledge. A core-pumped single-mode Yb-doped fiber amplifier is fabricated and the effects of pump power, seed power, and active fiber length on the in-band ASE are investigated in the experiment. It is found that a strong in-band ASE around 980 nm can be observed even with no obvious ASE around 1030 nm present. It is also found that with the increment of pump power, the in-band ASE can be enhanced faster than the signal light. By studying the effects of seed power and active fiber length, it is found that, although increasing the seed power and shortening the active fiber can both suppress the in-band ASE, the latter method is less effective than the former one. The theoretical study is also carried out in order to understand the difference between the in-band ASE and 1030-nm ASE. The experimental observations are also discussed qualitatively with the theoretical results. We believe that the pertinent results and discussions can provide significant guidance for understanding the in-band ASE in the Yb-doped fiber amplifier operating near 980 nm.


The present invention relates to a digital rights management structure, the portable storage device and, more particularly, to a digital content management method facilitating the portable storage device, and this movement of the rights object or encrypted content that relates to a content management method using the same. Digital rights management architecture according to an embodiment of the present invention consisting of a private key information and a secure portion that is composed of the encryption method information, authentication information required for mutual authentication with the said host device to decrypt the encrypted information by a host device It comprises limiting portion and a portion consisting of the encrypted content data to be accessed from the host device.


Said invention provides a method to realize time shifting function sow in network interactive tv ( IPTV ), system obtaining data from multicasting stream and putting in buffer zone , real time scanning buffer zone marking key frame. It promises a current system time reference time reference between Set-top box and stream medium server. When user given off skip forward, skip backwards, dragging, playing after pause etc request, set-top box exiting multicasting group, transmitting ordering request to stream medium server which responses request from set-top box and calculating time reference and client request required playing time difference finding out beginning playing position in buffer zone, then stream medium server relevant playing according to user different request, said invention can effectively complete skip forward, skip backwards, dragging time shifting function.


Urban gardens can harbour a high diversity of insects, which are critically important components of urban ecosystems. In this work, we investigate the richness and diversity of a major taxon of economic and ecological importance, the aphids (Hemiptera: Aphididae), and their main insect predators, the hoverfl ies (Diptera: Syrphidae) and ladybirds (Coleoptera: Coccinellidae), in urban gardens. We examined how variation in environmental factors associated with urbanisation (garden host plant abundance, garden plant richness, garden size, proportion of impervious surfaces in the surrounding area) directly and indirectly (via prey and predator abundance) infl uence the local diversity and abundance of aphids, ladybirds, and hoverfl ies. Sixty-seven domestic gardens located in southern England were surveyed during the peak period of aphid abundance, and the numbers and identity of aphids and their predators were recorded. We observed 45 aphid species (179917 individuals in total), 15 hoverfl y species (494 individuals) and 8 ladybird species (173 individuals). We found that aphid species richness and abundance were positively associated with utilised host plant abundance and garden plant species richness. Hoverfl y abundance was positively correlated with garden plant richness. The abundance of ladybirds was positively correlated with aphid abundance and garden plant species richness, and negatively associated to the proportion of impervious surfaces in the surrounding environment. The difference in responses between the two major taxa of aphid predators may refl ect differences in their behaviour and natural history. Our results indicate that overall increases in urban land cover are not favourable for ladybirds as a group, and that fi ne scale habitat variables that are determined by garden owners have the potential to greatly affect the diversity of aphids and their primary predators. * Corresponding author; e-mail: email@example.com INTRODUCTION Urbanisation is perhaps the most extreme form of widespread anthropogenic habitat modifi cation. Following urbanisation, most environmental variables (e.g., climate, water fl ow, biological diversity) are greatly altered from what previously existed (Smith et al., 2006). As a result, urbanisation can rapidly transform fundamental ecological processes (Goddard et al., 2010), which in turn can alter ecological interactions at multiple trophic levels (Kaye et al., 2006; Shochat et al., 2006). Unsurprisingly, urbanisation is considered a signifi cant driver of species extinctions (McDonald et al., 2008; Goddard et al., 2010) and represents a major proposed cause of insect decline (McKinney, 2008; Fattorini, 2011; Jones & Leather, 2012). The magnitude of the effects of urbanisation depends to a marked degree on the composition, amount, and management of green spaces in cities (Marzluff & Ewing, 2001; Eur. J. Entomol. 115: 140–149, 2018 doi: 10.14411/eje.2018.013


Listeners are able to rapidly shift their acoustic-phonetic categories in the face of speaker-specific variation. However, an open question is how top-down expectations can influence this perceptual adaptation. Under Adaptive Resonance Theory [Grossberg (2003)], if an acoustic token provides initial activation of a linguistic category, top-down expectations about that category can boost the resonance and lead to activation of the category even with an ambiguous token. Ambiguous tokens in positions with stronger expectations are hypothesized to lead to less perceptual adaptation than in positions with lower expectations. To test this hypothesis, two groups of participants will be exposed to 10 ambiguous s-∫ sounds during a lexical decision exposure task. The groups differ in where in the word these sounds will occur, either in the onset or coda of CVC words. Lexical bias, as a form of top-down expectations, is stronger for ambiguous coda sounds [Pitt and Szostak (2012)]. I predict that in a s-∫ categorizat...


The sustainable development is the only outlet of the resources city to walk out the difficult state of development.The appraisal of the resources(city's) sustainable development ability is the question which should be solved first.Using the domestic and foreign research on sustainable development as reference,this article constructs a series of appraisal system which suits to the resources cities.


The case of Nicola Sacco and Bartolomeo Vanzetti is one of the most im? portant and influential legal occurrences in American History. As much as the Dred Scott decision or Brown versus the Board of Education, it touched upon issues fundamental to American justice and freedom, and as such it has left its mark upon American society. Inevitably such a pivotal event as the execution of the two Italian radicals found expression in the arts, for the case was seen as having implications far beyond its legal, or even political, significance. Had Sacco and Vanzetti been merely criminals, or merely political extremists, their trial and death would have gone largely unremarked. But as recent immigrants, as members of a much-put-upon ethnic minority and as eloquent and committed personalities, they became the focus of frustrations, resentment, disillusion, empathy and admiration of many of their fellow citizens. Quite apart from the fact that the validity of their con? viction and sentence has often been challenged in years since, it is probable that all Americans, regardless of the degree of their familiarity with the famous case, feel that something was left unresolved in the Sacco-Vanzetti affair. It was this sense of disquietude, of uncertainty, which more than anything else characterized the artistic reaction to the case, and which in? forms thought and expression about it even today. To understand the origin of this disquiet it will be necessary to examine the facts in the case at least briefly, and turn some attention upon the trial and its aftermath.


In reacting eutectic SnPb solder with Ti/Cu and Cr/Cu/Au thin film metallization on Si wafers, we have observed spalling of Cu6Sn5 spheroids when the solder consumes the Cu. The formation of the spheroids is assisted by the ripening reaction among the compound grains. In addition we have observed an asymmetric spalling phenomenon using a sandwich structure, in which two wafers were soldered face‐to‐face. The spalling occurs predominantly at the interface at the bottom of the solder joint. It suggests that gravity plays a role.


Black and white photograph of Rice University Owls football player John Sylvester, posing in uniform number 83. Bottom of photograph reads "End, John Sylvester, Rice".


Fracturing of rock allows ingress of fluids that may be chemically distinct from native pore fluids. These external fluids can induce dissolution and precipitation, which may be enhanced by highly reactive, comminuted material and metastable highly deformed materials. Reaction products have important feedbacks via dissolution of asperities that affect fracture strength and friction properties. In this study, we examine dynamic fracturing of anhydrite/dolomite using triaxial direct-shear experiments with simultaneous x-ray radiography and tomography. The impermeable cores were fractured at a temperature of 50°C and a confining pressure of 3.5 MPa while being exposed to 500 kPa injection pressure of concentrated (18 wt%) BaCl2 solution. Once fractured, the barium solution invaded the primary shear fracture and the surrounding damaged region. X-ray radiographs and tomography revealed precipitation of barium sulfate and carbonate (barite/witherite). Despite the precipitation, the permeability of the fracture system changed little following the initial fracturing event. Precipitation was likely confined to relatively stagnant flow regions, with more open regions sustaining high flow rates. The experimental results demonstrate laboratory-induced fluid-rock reaction and precipitation in fracture systems and reveal the important role of grain-scale mineralogy and flow pathways on the extent of reaction and the impact of precipitation on permeability.


DURING the nineteenth century most blacks viewed the voting franchise as a panacea for solving their problems. What they failed to realize was that their success or failure in achieving the goal of equal rights was dependent upon many variables operating in American society. Pennsylvania, a state where during the nineteenth century blacks encountered the determined opposition of prejudiced whites, offers an excellent example of the potential for improving their conditions and the problems which voting rights presented to northern blacks. The Pennsylvania Abolition Act of 1780 provided for the gradual abolition of slavery but made no comment as to the political status of free blacks. The question as to whether blacks could legally exercise the right to vote depended upon the interpretation of the state's Constitution of 1776 which extended the franchise to "every freeman of the full age of twenty-one years, having resided in this State for one whole year before the day of election for Representatives and paid public taxes during that time. . . ." The key word in this passage was freeman. Many white officials considered this term to exclude blacks due to their past status. Without a revision in the language of the Constitution or a ruling by the courts, the status of black voters remained ambiguous and was left to the discretion of local officials. An opportunity to clarify the wording of the Constitution developed in 1789 when the citizens of Pennsylvania called for a constitutional convention to revise that document. When the suffrage article was brought up for consideration, several antiblack


A 1-year-old working Kelpie developed pneumothorax and focal peritonitis after inhalation of a grass awn that migrated from the lung, through the diaphragm, into the peritoneal cavity. Radiographic evidence of sternal lymph node enlargement was fundamental in the diagnosis of intraperitoneal disease and prompted abdominal ultrasound leading to definitive diagnosis.


The essay clarifies the dialectical unity between development with the times and the Party ' s lines,which comprises ideological line,political line,organizational line and mass one.In addition,it analyzes on the logical relation of development with the times and the Party ' s linescreativity and its nature as well.


The invention provides a sound absorption wall and a construction method thereof. Particularly, the construction method includes the following steps that 1, the surfaces of porous ceramic sound absorption bricks are physically ground; 2, the porous ceramic sound absorption bricks and adhesive slurry are used for laying, a base layer is obtained, and the adhesive slurry is formed by mixing mortar, lime, additives and water; 3, sound absorption slurry with the thickness of 12 mm to 18 mm is plastered, a sound absorption layer is obtained, and the sound absorption slurry is formed by mixing mortar, floating beads, rubber powder, additives and water; 4, mortar with the thickness of 4 mm to 6 mm is plastered, and a transition layer is obtained; 5, face bricks are attached, and a decoration layer is obtained, wherein the additives are regenerated EPS or fibers or cellulose ether, and the grain diameter of fine sand ranges from 0.25 mm to 0.5 mm. The sound absorption wall has good buffering and absorption effects on sound waves, high fire-resistant and high-temperature-resistant performance and high mechanical strength. The absorption rate of the sound absorption wall for noise at the frequency of 50 Hz to 10,000 Hz exceeds 60%.


Quite a number of experimental techniques are used in biomedical research involving the registration of flow velocities of biological fluids. These arc: particle image velocimetry, ultrasonic Doppler velocimetry, speckle microscopy, transmission grating microscopy, etc. Each of these methods has its advantages but none of them provides means to study all the variety of biological objects and dynamic phenomena, via performing noninvasive measurements. An essential alternative method is laser Doppler (LD) spectroscopy and microscopy, based on the registration of Doppler frequency shifts of laser radiation scattered from moving particles. The method yields high spatial and temporal resolution and hence can be used in different fields of biophysics and biomedicine [1,2,3]. The amount of the integral information, averaged over all the particles traversing the probe volume, the real-time mode of measurements, the possibility of registration of the flow velocity profiles -all this makes LD microscopy an efficient method enabling to study biological objects of different levels of complexity with broad range of optical properties. The possibility of fluid flow measurements in live objects with the LD technique was first shown in 1972 [4] and since then the potentialities of this technique have been studied extensively [5, 6, 7J. Nonetheless, though there arc no apparent technical reasons which would prevent from designing an LD microscope (LDM) as a commercial device, LD microscopy has not become yet a conventional technique. There still exist problems of Doppler spectra interpretation and evaluation of data experimentally obtained from biological objects with different opticai properties. These will be discussed below. We describe here an LDM designed in Moscow State University specifically for biophysical and biomedical applications on the basis of our earlier experience in application of LD spectroscopy to the study of intracellular hydrodynamics [8] and of haemodynamics [9). The potentialities of the LDM are illustrated by the results of real time measurements of oscillating flow velocities in relation to two different phenomena: 1 -protoplasmicstreaming in plasmodium of myxomycete Physarum, and 2 -bloodflow in aquarium Danio rerio fish embryo. To carry out measurements in biological objects with different optical properties and a broad range of values of measured parameters the following innovations have been introduced: - inl.roduction of controlled high stability frequency shift in the probing beams; - two-steps formation of optimal probe volume; - generation of the output signal with high signal-to-noise ratio both in analog and in photon ounting regimes; - arrangement of computer controlled fast scanning;- elaboration of the software for signal processing and calculation of parameters under study


ABSTRACT Round slices (2 mm thick) of fresh apple and of apple subjected to osmo-dehydration processes in sucrose syrups until reaching aw values of 0.979, 0.968. and 0.958. were air-dried at 50. 60. and 70°C. Analysis of the drying curves showed that the products do not present a constant rate period (except for fresh apple) but showed two falling rate periods. Initial aw greatly affects the fraction of water lost during the drying processes. The use of the Fick's Second Law was not adequate to describe the experimental drying curves. However, apple drying processes can be modeled by the Characteristic Drying Curve model, using several equations (polynomial and logarithmic) with a high confidence level. The parameters of each equation showed a great dependence on product's aw These models can be used to predict drying curves within the studied limits in each case, presenting great advantages when compared to classical models based on effective diffusion coefficients.


Automation is not a new concept in organisations as a way to improve their processes. However, Robotic Process Automation is an emerging form that automates processes with software, which the industry calls robots. These robots perform repetitive and low-complexity tasks previously performed by humans in front of a computer perhaps the most commonly used feature in a company nowadays. Using the Design Science Research methodology to build up this thesis, it argues that RPA is being used idly compared to what it could be using process improvement techniques before applying the automation itself. Thus, this thesis proposes a new approach to RPA: using techniques of Lean. This thesis assesses two market leaders on RPA, and suggests a framework of activities for organisations that are investing in RPA and that want to take advantage of the capabilities that this technology currently offers. The majority of the proposal demonstration was done in a Portuguese private bank, in three processes. It had an overall positive evaluation in the field or the simulations, depending on the different cases. Comparing RPA and Lean RPA projects in the amount of resources (time, FTE) needed to carry out business processes, the latter approach presented values significantly lower and, consequently, satisfactory.


In the power supply system, an important place belongs to autonomous power systems. Considering the need to reduce greenhouse gas emissions and the use of renewable energy sources, the primary source of energy in an autonomous power system can be a wood gas generator. The fuel for such a generator is biomass. The wood gas enters the internal combustion engine, which drives a synchronous generator. The resulting electrical energy is supplied to the consumer. The article presents an experimental plant for generating electric energy on the basis of wood gas, and provides the results of studies in the effect of the used power of the synchronous generator on the gasifier fuel consumption and the amount of gas produced by it. The experimental plant contained a downdraft gasifier, the feature of which is that the combustion and recovery zones have the same diameter. The gasifier was equipped with gas purification filters and a gas cooler. The resulting gas was supplied to the internal combustion engine through a special mixer equipped with the air supply control valve. A synchronous generator was used to convert the mechanical energy of the engine into electrical energy. As the engine and electric generator petrol-electric AC set AB-4-T/400-M1 was taken. The petrol-electric set has a rated power of 4 kW and produces a three-phase current with a voltage of 220 V. During operation of an experimental gas-operated plant, the growth of the consumed electric power by 12 times causes the linear growth of gasoline consumption by 1.59 times and air consumption by 1.63 times. During the operation of the wood gasoperated experimental plant, an increase in electrical power consumption by 9.5 times causes a linear increase in gas consumption by 2.14 times and air consumption by 1.38 times. The cost of the generated electricity when using wood gas is 2.4 times less than when using gasoline.


Molecular Modeling is a powerful tool of computational chemistry and is widely used in many research areas, such as drug design or biotechnology. This volume publishes, in printed form, all articles on the subject published by the Journal of Molecular Modeling online in the Internet during 1997. The printed version guarantees easy access to all articles without connecting to Internet; the accompanying CD delivers all articles including the multimedia applications and supplementary material not available online.


The mechanism of fast crystallization of In-Se phase-change optical recording films by Tl addition is studied determining atomic arrangement by XPS and using crystallization kinetics of a written amorphous state. Thallium ions in the In-Se-Tl film found to be monovalent, so they cut atomic bonds. The minimum crystallization time by an laser-beam irradiation is shorten to 0.2µs by the Tl addition. The Tl addition increases both the activation energy and frequency factor for crystallization. Cobalt addition to the In-Se-Tl film not only stabilizes amorphous state but also makes erasing faster. The minimum crystallization time is further shorten to 0.06 µs. The retention time of written dot's amorphous state is estimated to be 100 years at 150°C. More than 2500 times of single-beam overwrite is achieved using In-Se-Tl-Co disk. Carrier to noise ratio of a 2.5MHz signal is 54dB at 1800rpm.


The development and the application of the Numerical Electromagnetic Code (NEC) - Method of Moments are described. NEC is based on a previous method of moments code for thin wires, the Antenna Modeling Program (AMP), and yields improved estimates of the performance of antennas mounted on shore stations, ships, aircraft, and spacecraft. The NEC can model antennas in free space, over a perfectly conducting ground plane, and over finite conduction (lossy) earth.


Optimal periodic control is an effective technique to reduce aerodynamic heating and fuel consumption of hypersonic cruise vehicles. Herein, this optimal control problem has been solved by nonlinear programming and passed the posteriori check of optimality. The results indicate that the lift coefficient and velocity in dynamical model could be recognized as constants. Accordingly, the original 3D system consists of velocity, flight path angle, and altitude, which could be decoupled into a 2D subsystem and a 1D one. The 2D subsystem could describe the correlation between the flight path angle and altitude. And the period length is mainly dependent on the maximum altitude difference. The 1D subsystem has been proved to be feasible to describe the variation of kinetic energy or velocity. On basis of the subsystems, the heating and fuel performances of periodic cruise have been studied. The heating performance is mainly dependent on the maximum altitude difference, and the fuel consumption is mainly dependent on the drag coefficient. The features concluded in this paper can support rapid trajectory planning or suboptimal feedback design of hypersonic cruise vehicles.


This paper describes Internet of Things (IoT) and Machine-to-Machine (M2M) communications as the enablers of smart city initiatives. The challenges in modern cities are briefly identified. Utilization of IoT based applications and services could mitigate these challenges. The paper then introduces an architecture based on oneM2M standards for smart cities. The key elements of the architecture are described along with the common service functions. The main contributions of the work are -- (i) uniform metadata exchange with things using Sensor Markup Language and its extensions, (ii) uniform description of heterogeneous things for configuration management, (iii) OMA Lightweight M2M based device management framework, (iv) resource discovery framework and (v) Machine-to-Machine Measurement framework based M2M data processing and analytics. The core functionalities of these frameworks are exposed to the consumers through RESTful web services. An application scenario on crowdsourcing in the smart cities is highlighted. Finally the paper concludes with future research directions.


OBJECTIVE:To evaluate the efficacy and safety of thrombus aspiration plus tirofiban applied during emergency percutaneous coronary intervention(PCI) in patients with acute myocardial infarction.METHODS:Ninety emergency PCI candidates with acute myocardial infarction and ST segment elevation from January 2009 to October 2011 were randomly assigned to receive either trial group(thrombus aspiration plus tirofiban) or control group(tirofiban) of 64 each.The TIMI(thrombolysis in myocardial infarction) blood flow before and after operation,the left ventricular ejection fraction(LVEF) during hospitalization and incidence of MACE(major acute coronary event) and incidence of bleeding complication etc within one month after operation were recorded for the two groups.RESULTS:The LVEF during hospitalization and the TIMI flow instantly after operation in the trial group were significantly higher than in the control group;however,the incidences in MACE and bleeding complication were not significantly different between the two groups.CONCLUSION:Thrombus aspiration plus tirofiban applied during emergency PCI was proved to be safe and effective for acute cardiac infarction in that it can reduce the incidence of no-reflow yet without presence of fatal complication of bleeding.


In this research, it is aimed to examine the data analysis and research findings related to the effect of school administrators' perceptions of corporate image on organizational identification levels. In this research on the effect of school administrators' perceptions of corporate image on organizational identification levels, the survey method was used to collect data in parallel with performing data analysis. The sample of the research consists of 40 school administrators selected by random sample who worked in official primary schools of Bahçelievler district of Istanbul province in the 2016-2017 academic year in which the research was conducted. According to the findings of the research, school administrators' perceptions of corporate image are medium and their organizational identification levels are high. With the perception of corporate image and corporate image the relationship between organizational identification organizational identification levels of correlation between weak, has a significant positive correlation (R=0.344, p=0,030<0.05). The result was obtained that there was a weak but positively significant relationship. A regression analysis to determine the relationship of cause and effect between corporate image and organizational identification was found to be statistically significant (F=6,235; p=0,017 for<0.05). As a determinant of the level of organizational identification, it was found that its relationship with corporate image variables (explanatory power) was weak (R2=0.118). The level of corporate image of managers increases the level of organizational identification (ß=0.905). Organizational identification levels of school administrators with perceptions of corporate image; it was concluded that there was no significant difference according to seniority year, educational status, marital status and age. The perceptions of corporate image of those who had 5 years of study at school and less increased more than those who had 5 years and more. On the other hand, there was no statistical significance of organizational identification levels according to the variable of the working year at school. In accordance with the scientific statistical data obtained, suggestions were made to researchers and senior Ministry of Education (Ministry of National Education) managers for scientific studies.