This thesis details a series of investigations into the controls on surface ocean
concentrations of the climatically relevant, biogenic sulphur compound, dimethyl
sulphide (DMS) at regional to global scales. The primary focus is upon the role of
solar irradiance and metrics of biological activity in modulating DMS concentrations
using bivariate and multivariate statistical techniques in conjunction with three
different data sets from multiple spatial and temporal scales.
Firstly, a statistical investigation into the proposed strong positive relationship
between surface DMS concentration and the average mixed layer irradiance (solar
radiation dose: SRD) was undertaken using DMS data from a series of cruise tracks
from the Atlantic Meridional Transect (AMT) programme, primarily from the
oligotrophic Atlantic gyres. Positive correlations were found between DMS and (a)
SRD formulations using concurrently sampled in situ data (ρ=0.55 n=65 p<0.01), (b)
SRD formulations based on using climatological data (ρ=0.74 n=65 p<0.01) and (c)
a ultraviolet radiation dose (ρ= 0.67 n=54 p<0.01).
The next analysis investigated whether the inclusion of a biological variable
(chlorophyll or primary production) alongside irradiance could explain additional
variance in DMS concentrations. This analysis employed a database of cruise data
from a range of biogeochemical domains, latitudes and trophic conditions (AMT, the
Barents Sea, the Atmospheric Chemistry Studies in the Oceanic Environment
(ACSOE) research campaign and the DImethyl Sulphide biogeochemistry within a
COccolithophore bloom (DISCO) study. Using multiple linear regression (MLR)
analyses, it was found that the combination of, in situ rate of primary production and
underwater irradiance accounted for significant variance in DMS concentrations in
data from discrete depths within the euphotic zone (R2 = 0.55), from near-surface
waters (R2 = 0.66) and within depth profile integrated data (R2 = 0.40).
The final analysis is an investigation into global surface DMS dynamics using the
global surface seawater DMS database (http://saga.pmel.noaa.gov/dms/) and satellite
based retrievals of irradiance and primary production rates. A novel composite
approach which combines multiple MLR models applied to Longhurst biogeochemical provinces, and using monthly averaged data, explained maximum
variance. Models developed within a randomly selected training subset were able to
explain significant variance within the remaining validation subset using this
composite approach (predicted vs. observed ρ = 0.93, p = 0, n = 107). Previous
studies had been unable to identify a strong link between DMS and indicators of the
biological community (e.g. chlorophyll) at large scales. Our results suggest that a
link exists between ecosystem productivity and DMS concentrations, and moderated
by processes directly influenced by solar irradiance. These findings on large scale
ecosystem controls on DMS, based on remote-sensing datasets, provide an
advancement in the understanding and prediction of global-scale surface DMS
concentrations.


We prove that the knot invariant induced by a Z-homology 3sphere invariant of order ≤ k in Ohtsuki's sense, where k ≥ 4, is of order ≤ k − 2. The method developed in our computation shows that there is no Z-homology 3-sphere invariant of order 5.


An algorithm for predicting the amplitude of 40-Hz auditory steady state response (ASSR), which is an indicative of depth of anaesthesia, is presented in this paper. The amplitude of 40-Hz ASSR is an indicative of the depth of anaesthesia. Predicting this amplitude will help anesthesiologists in choosing the dose of the anaesthetic agents and have an estimation of the patients' next depth of anaesthesia state. The method is applied to the 40-Hz ASSR signals recorded from 20 human subjects during surgical operation. The algorithm uses sequential feature selection and multi-linear regression for choosing the most informative features and estimating the amplitude of ASSR on the next cycle and at the end of induction stage, when the patient looses his/her eyelash reflex. The algorithm uses the dose of anaesthetic drug, some of the demographics and medical parameters of the patients and their previous ASSR cycles for prediction. As the system provided with more ASSR cycles, the error in prediction decreases and estimation gets more accurate. The method is applied on the induction phase where patients' depth of anaesthesia changes very fast but it is applicable to all other stages of anaesthesia as well.


'Aloha' (Reg. No. CV-3, PI 652948) seashore paspalum (Paspalum vaginatum O. Swartz) was developed at the Everglades Research and Education Center, Institute of Food and Agricultural Sciences, University of Florida and jointly released by the Florida and Hawaii agricultural experiment stations. It was initially approved for release in early 2005 and a pending plant patent was submitted in late 2005. This variety of seashore paspalum was selected as an open-pollinated progeny derived from naturalized local landraces growing on the island of Hawaii and was tested in southern Florida under the coded breeding line number H99–47. Aloha was selected for improved agronomic, horticultural, and host-plant resistance traits including a faster rate of crop establishment and ground coverage, darker and deeper green leaf color, and superior resistance to the greenbug aphid (Schizaphis graminum Rondani; Homoptera:Aphididae). In comparison to a set of standard varieties, Aloha attained 50% plot coverage in less than 4 mo whereas the standards took, on average, more than 5 mo. The leaf color of Aloha was a darker green and had a deeper hue than the standard varieties, and the greenbug aphids took longer to reach reproductive maturity, had a shorter lifespan, and produced fewer offspring when cultured on Aloha. Aloha also exhibited a morphology distinct from the standards for a set of measured infl orescence and vegetative traits.


We have recently identified a common ALL patient which harboured a chromosomal fusion between the TEL gene on chromosome 12 and the ABL gene on chromosome 9. We designed an RT‐PCR assay to screen 186 adult ALL and 30 childhood ALL patients for this novel translocation. We were unable to identify any additional cases with a TEL/ABL fusion product.


Background Patients with antiphospholipid syndrome (APS) have been evaluated in the context of accelerated atherosclerosis in numerous studies, bringing this concept into the focus regarding proper treatment of this population of patients. Objectives Carotid intima-media thickness (cIMT) has been established as a distinguished marker of cardiovascular risk. The aim of this study was to evaluate relationship between presence of more than one antiphospholipid antibody (aPL) and cIMT values in SLE patients with secondary APS. Methods We analyzed 80 patients with systemic lupus erythematosus (SEL) and secondary APS 74 female (92.5%) and 6 male (7.5%), average age 49.4±13.1years. In all patients presence of lupus anticoagulans (LA), anticardiolipin (aCL IgG/IgM) and anti-β2 glycoprotein-I (anti-β2GPI IgG/IgM) antibodies has been established, and they were classified into group with only one or more than one aPL present in any combination. Measurement of cIMT has been performed on common carotid artery (CCA), its bifurcation (CCAbiff) and internal carotid artery (ICA) on both sides. We defined cIMT values 1.1mm and higher as plaque presence Results There were 63.8% patients with more than one aPL present. Prevalence of standard atherosclerotic risk factors was below 40%. Age, hypertension, presence of diabetes mellitus and hyperlipidemia resulted in higher values of cIMT in studied group patients. Average values of cIMT were significantly higher in patients with more than one aPL present for almost all segments of carotid trunk (CCA right, p=0.009, CCA left, p=0.034, CCAbiff right, p=0.093, CCAbiff left, p=0.632, ICA right, p=0.027, ICA left, p=0.544). After adjustment for age, current cigarette smoking, diabetes, hypertension and hyperlipidemia, the relative odds for atherosclerotic plaque presence on carotid arteries in SLE patients with APS and more than one aPL present was 4.19 (95% confidence interval 0.09 to 0.95, p=0.041). Conclusions Presence of more than one aPL in SLE patients with APS additionally accelerate atherosclerotic continuum. In this subgroup of APS patients more aggressive approach towards prevention and control of standard atherosclerotic risk factors is crucial. Acknowledgements This work was supported by research grant number 175041 for 2011-2015, issued by the Ministry of Science of the Republic of Serbia. Disclosure of Interest None declared


Summary. To study the correlation between total Hepatitis C virus (HCV) Core antigen (Ag) and HCV‐RNA, and to assess the proficiency of HCV Core Ag testing in monitoring and predicting virologic response during and after pegylated interferon (PEG‐IFN) and ribavirin combination therapy.


This themed issue intends to open up new vistas on the history of emotions. It does so with articles that examine community-based or spatially defined emotional styles that were simultaneously performed within larger socio-cultural contexts. Following this approach one might – for example – discern 'Muslim', 'Hindu', 'British' and 'Anglo-Indian' emotional styles within colonial South Asia around 1900 as well as diverging modes of thinking about, handling, generating and expressing emotions that prevail in work-, leisure- or consumption-spaces within contemporary Berlin. As the contributors to this issue demonstrate, capturing these multiplicities of co-existing styles and analysing their interactions enhances our understanding of the diachronic variability and synchronic diversity of emotional patterns and practices. Put differently, this issue of Rethinking History seeks to expand the scope of previous approaches that were informed by rather monolithic understandings of emotionality.1 Pursuing this agenda, this editorial first offers a working definition of emotion and outlines the concept of 'emotional styles'. This notion not only produces new narratives and perspectives in a variety of disciplines, including history and sociology, but also raises fundamental questions about different understandings of the actor, that is, the subject and its potential for choice and agency. These matters are addressed in the second part of this editorial, while the third part raises questions about emotional styles in historiographical practice – how do we come to terms with the historian's emotions?


Bipedal locomotion is one of the main research topics in humanoid robotics due to the complexity of generating dynamically stable gait patterns in robots that are generally very unstable. Good walking performance requires diverse and complex control strategies based on a mathematical model of the robot. Here, a methodology to easily generate stable bipedal locomotion patterns in a humanoid robotic platform is presented. Using a simulation environment and a simple programming method, the robot gait, stability and general behaviour are first simulated and then transferred to the actual machine. Three gait patterns are developed according to the biomechanics of human walking and validated using a humanoid robot platform. The robot exhibits good performance in terms of stability, displacement and velocity. The proposed methodology allows the study of locomotion in biped robots and can serve as a basis for developing controls in closed-loop schemes.


Chinese Higher Education Law stipulates that tuition charged by a university shall be determined on the basis of per capita cost that may accrue by the university, while taking into account of affordability of the average families in the society. However here may arise two theoretical points. Firstly, the measurement of education cost should be exact in order to serve as the base for tuition collection; Secondly, a foundation of the weight ratio should be set up in order to truly represent the portion of the education expenditure to be shared by students. In fact, the efforts in measuring education cost do not constitute necessary premises in tuition determination even though it is helpful in regulating the practice of tuition collection. The approach of price control has proved to be an alternative to above regulating tuition among universities.


Significance
 The government's precarious fiscal position means that some taxes will be increased, but the rate of VAT will remain unchanged. Much of the adjustment will come about from the removal of subsidies on petrol and diesel. Labour laws are to be liberalised, a move favoured by employers but resisted by unions.

 Impacts
 Export performance will depend greatly on movements in the price of crude.
 Ecuador's scheduled departure from OPEC in January will allow for increased oil production.
 The price rises caused by the removal of fuel subsidies could drive sustained public unrest.


A series of multiple nanosecond molecular dynamics simulations has been carried out for a dipalmitoylphosphatidylcholine lipid bilayer system in water solution, with ubiquinone (UQ) freely moving inside the bilayer. The focus is on the mobility and the preferential positions of the quinone molecule. Two different tail lengths have been used in the simulations to investigate the effect of the long tail, attached to the quinone-ring. The lateral diffusion rate in the nanosecond time scale, obtained for 2,3-dimethoxy-5-ethyl-6-methyl-1,4-benzoquinone (short tail, denoted UQ-et) was at 60 °C found to be roughly the same as that for the lipids. The headgroup of UQ-et preferred a location between the 4th and the 10th carbon atom in the palmitic chains of the lipids. For UQ-10 (10 unit long isoprenoid tail), two preferred positions of the headgroup were found in separate simulations with different initial configurations for the quinone; one close to the lipid headgroups, the other in the membrane midplane. Trans...


Hypoxia‐inducible factor‐1α (HIF‐1α) is a transcription factor that is involved in tumour growth and metastasis by regulating genes involved in response to hypoxia. HIF‐1α protein overexpression has been shown in a variety of human cancers, but only 2 studies have documented the prognostic relevance of HIF‐1α expression in breast cancer. The aim of our study was to determine accurately the impact of HIF‐1α expression on prognosis in a large series (n = 745) of unselected patients with invasive breast cancer in terms of overall survival, local recurrence and distant metastasis risk. HIF‐1α expression was investigated using immunohistochemical assays on frozen sections, and correlated with patients' outcome (median follow‐up = 13.5 years). Univariate (Kaplan‐Meier) analysis showed that high levels of HIF‐1α expression (cutoff = 10%) significantly correlated with poor overall survival (p = 0.019). HIF‐1α expression correlated with high metastasis risk among the whole group of patients (p = 0.008). Multivariate analysis (Cox model) showed that the HIF‐1α predictive value was independent of other current prognostic indicators. Moreover among node negative ones, HIF‐1α expression was also significantly predictive of metastasis risk (p = 0.03) and of relapse (p = 0.035). All the data suggest that HIF‐1α is associated with a worse prognosis in patients with invasive breast carcinoma. Furthermore HIF‐1α immunodetection may be considered as a potential indicator for selecting patients who could benefit from specific therapies interfering with HIF‐1α pathway. © 2005 Wiley‐Liss, Inc.


Abstract This study reports the antidiarrheal potential of Lithocarpus dealbata. (Miq.) Rehder (Fagaceae) and Urena lobata. L. (Malvaceae) used in the traditional medicine system of the Naga tribes of in India. The antidiarrheal efficacies of the seed extract of L. dealbata. and leaf extract of U. lobata. were evaluated in murine models by three different approaches: (i) castor oil–induced diarrhea, (ii) PGE2-induced enteropooling, and (iii) small intestinal transit. The 800 mg/kg dose of methanol extracts of both plants showed significant (p < 0.001) inhibitor activity against castor oil–induced diarrhea and PGE2-induced intrafluid accumulation. Both extracts also showed a significant (p < 0.001) reduction in the gastrointestinal motility in charcoal meal test. Acute toxicity tests did not reveal any sign of toxicity in the animals. The observed results could explain their use as antidiarrheal agents in traditional medicine.


Advances in the Industrial Internet of Things (IIoT) enable complex machine data analysis and information extraction to improve manufacturing throughput. However, existing approaches are fixated on improving prediction accuracy and overlook the implications of model drift on edge-based devices. For this reason, we present a real-time system for monitoring RUL model performance drift via incremental learning. Besides, edge devices are compute and memory bounded with diverse configurations. To address this problem, we propose to re-train the RUL prediction model on an edge server and conduct extensive experiments to determine the optimal quantity of batch-sized data that exhibits the lowest error deviation compared to tabula rasa model training. Our findings demonstrate that incremental training yields an average training time savings of 60% for an open-source industrial dataset while incurring a mean difference of −1.1% and −4.9% for prognostics performance metrics root-mean-square-error and score, respectively.


We investigate the effects of Fe-dopant concentration on the structure, as well as optical, electrical transport and magnetic properties of SrTi1− x Fe x O3 (x = 0.00, 0.10, 0.20, 0.30, 0.40 and 0.50) nanoparticles prepared by sol–gel method. The dopant-induced changes are studied by X-ray diffraction (XRD), Raman, optical absorption, impedance and magnetic measurements. The results show an average particle size of about 15–30 nm, depending on the Fe-doped concentration. The decrease in lattice parameters and the change of phonon modes related to structural changes, decreasing gap with increasing dopant concentration in conjunction with increasing grain boundary contribution to the impedance. The Fe-doped content has affected the structure, absorption and Raman spectroscopy of the samples. These indicate that the Fe ion has replaced the site of Ti in unit cell. By this method, we have decreased the annealing temperature considerably than that in the conventional solid-state reaction.


Introduction: Pharmacogenetic (PGx) testing can be useful for providing information about a patient's drug response by increasing drug efficacy and decreasing the incidence of adverse drug events. While PGx tests were previously only offered to patients under healthcare provider supervision, they are now available as direct to consumer (DTC) tests. This study aimed to assess how accurately individuals from the general population were able to interpret a sample PGx test report and if accuracy differed based on individuals' numeracy or prior genetic counseling (GC). Methods: We surveyed 293 individuals from the general population, ascertained through ResearchMatch. The survey included questions about PGx test interpretation, numeracy, and genetic literacy. Results: In our cohort, numeracy level impacted PGx result interpretation, with those of high numeracy performing statistically significantly better on both the table format and graphical format (p value = 0.002 and p value <0.001, respectively) and genetic knowledge questions (p value <0.001) than those with low/average numeracy. In addition, previous GC did not impact test interpretation or genetic knowledge, but the number of individuals with prior GC was small (n = 26). Discussion/Conclusion: We found that numeracy had a significant impact on correct interpretation of PGx test reports. Because many individuals in the USA have low numeracy levels, it is extremely important that patients do not make their own medication management decision based on the test results and that they consult with their physicians about their PGx testing. The importance of consultation and discussion with providers about results should be emphasized on the test report.


BACKGROUND
To evaluate the effects of MI desensitizing varnish treated before or after bleaching on the mineral component of enamel and surface topography.

METHODS
The coronal portions of 10 freshly extracted bovine teeth were segmented for a total of forty specimens. Enamel specimens obtained from each tooth were randomly divided into four groups(n=10). Group A:No bleaching. Group B:Bleaching with 40% HP. Group C:MI varnish applied before bleaching. Group D:MI varnish applied after bleaching. The calcium and phosphorus levels of the specimens in each group were determined by EDS. Morphological changes were observed using SEM.The One-way ANOVA, Tukey HSD tests were used for statistical analyses (α=.05).

RESULTS
The mean Ca content of Group B was significantly lower than those of Groups A,C, and D(P<0,05). The mean Ca content of Group C was significantly lower than that of Group A(P<0,05). There was no significant difference between the other groups in terms of Ca content(P>0,05). The mean P content of Group A was significantly higher than those of Groups B-D(P<0,05). There was no significant difference between Groups B-D in P content(P>0,05).

CONCLUSIONS
Application of MI varnish before or after in-office bleaching was effective in reducing mineral loss. However, applying MI varnish after bleaching was more effective. Int J Periodontics Restorative Dent. doi: 10.11607/prd.6528.


1. We consider two-terminal circuits with an exponential conductivity law. The concept of resistance is introduced and its interpretation given in terms of transport problems for various values of the exponent. Conditions are given that ensure that the resistances satisfy the metric and ultrametric inequalities. Thus the resistance may be regarded as the distance between the terminals of the circuit. The general problem of computing circuits and its connection with optimization of flows [ 1 ] is considered in [2] and [3]. In this note we use the concepts and notations introduced in [3].


A double-blinded controlled field trial was organized from November 2011 to may 2012 in 13 professional BB farms as a split-plot equitably dividing the pregnant dams in each farm in 2 groups based on their gestation length and parity and randomly assigning them to the 2 mineral treatments. Mineral supplements of 100 grams were fed daily to 699 pregnant dams for at least 2 months before calving. Group A (n=358) received 4 mg Se, as 2 mg Optimin SeY (63% seleno-methionine Se enriched yeast, Nutreco), and 2 mg Na2SeO3, 140 mg Cu as 70 mg CuSO4 and 70 mg Optimin Cu (Nutreco), and 500 mg Zn as 250 mg ZnSO4 and 250 mg Optimin Zn (Nutreco). Group B (n= 341) received the same amounts of Se, Cu, and Zn, but only in their inorganic form. Supplements also contained sufficient I, Co and vitamins. Farms were visited monthly to record zootechnic and health data from dams and calves. Calves were weighted at birth and at the end of the study to calculate their average daily gain (ADG). In 6 farms, calves were suckling while bucket-feeding was applied in the others, using lactoreplacers in 5 farms and cow's milk in 2 farms. All calving were achieved by caesarean-section. Colostrum was sampled at calving and analyzed for total protein (densitometry) and IgG content. Calves were blood sampled between 48 h and 7 d of life to test their passive immunoglobin transfer on serum by refractometry.


Nephritis in systemic lupus erythematosus (SLE) is a factor contributing to early development of atherosclerosis (AS).

 The aim of the study is to determine differences in cardiovascular risk factors and AS in SLE pts with and without lupus nephritis (LN).

 The study included 162 females, age 35 [26–43] years (median [interquartile range 25–75%])) with SLE (ACR,1997). We divided SLE pts on two groups, comparable in age: the 1st group is the pts with LN (n=84, 52%), the 2nd - without LN (n=78, 48%). We considered traditional factors of cardiovascular disease (CVD): (smoking, family history of CVD, blood pressure, cholesterol (total, HDL, LDL) and triglyceride (TG) levels, body mass index, diabetes mellitus) and SLE-related factors (age at onset, duration, clinical features, SLE Disease Activity Index (SLEDAI-2K) and the Systemic Lupus International Collaborating Clinics damage index (SLICC/DI), treatment with steroids); intima-media thickness (IMT) and the 10-year risk for coronary events. Carotid intima-media wall thickness of common carotid arteries was measured by high resolution B-mode ultrasound. The 10-year risk for coronary events was estimated by the Framingham risk equation.

 Median SLE duration was 8,0 [2,3–17,0] years, SLEDAI 2K – 8 [3–16], SLICC/DI score – 2 [0–3], duration of prednisone treatment – 72 [26–141] months. SLE pts from the 1st group had higher prevalence of hypertension (61% vs 36%, p<0,01), systolic blood pressure (130 [110–150] vs 120 [110–130]mm Hg, p<0,01), diastolic blood pressure (80 [70–95] vs 70 [70–80] mm Hg, p<0,05), TG concentration (136 [98–184] vs 100 [61–162] mg/dl, p<0,01), Framingham Risk Score (5 [1–30] vs 1 [1–27]%, p<0,05), SLEDAI-2K (12 [5–19] vs 4 [2–10], p<0,ehz745.08501), SLICC/DI score (2 [0–4] vs 0 [0–2], p<0,01), prednisone therapy duration (95 [26–192] vs 44 [14–98] months, p<0,05), prednisone cumulative dose (34,4 [13,6–82,5] vs 15,7 [6,2–35,2] g, p<0,001), mean IMT (0,73 [0,65–0,83] vs 0,67 [0,61–0,75] mm, p<0,01), than the pts from the 2nd group. There is no difference in CVD frequency in these groups (17% vs 8%, p=0,084).

 SLE patients with and without LN had no difference in frequency of clinical manifestations of AS (CVD), but had a greater value of mean IMT, Framingham Risk Score and a higher incidence of both traditional (hypertension, TG concentration) and SLE-related (disease activity, prednisone therapy) risk factors for AS.


Sea-sky line extraction under complex sea-sky background plays a very important role in image processing for the detection and tracking of targets. In this paper, different from traditional methods, we proposed a novel sea-sky line extraction approach with straight line fitting based on line segment detection. Firstly, a fast and robust line segment detection method was used to locate the sea-sky region roughly. In this algorithm, the line segment region detection can be completed in linear time. Then, the accurate parameters of sea-sky line is computed in an improved linear fitting method based on least squares. The experimental results indicate that the proposed approach can effectively extract the sea-sky line from sea-sky background image.


Within the article, the peculiarities of the improvement of the informational culture of the future teacher of the primary school as the process of knowledge and means which influence the actualization of the informational activity were determined. During this activity, the future teacher expresses his or her aesthetic tastes, requirements, interests, ideas, judgments, beliefs and intellectual abilities which begin to form within the student due to the leadership of the teacher. The goal of the article is the elucidation of modern methodical approaches to the improvement of the informational culture of the future teacher during the process of studying linguistic disciplines. The subject of the research is the pedagogical conditions of the increasing of the informational culture of the future specialist. The theoretical-methodological basis of the research is made up with: classical and modern attainments of the world and national pedagogics, modern research on problems of the education's informatization, the activity theory of teaching and development of the personality. For the achievement of the determined goal and the solution of the determined tasks there was implemented the complex of research's methods: theoretical – analysis of the psychological, pedagogical, educational-methodical literature on the research's problem; synthesis and generalization, comparison; work with the experience of teachers of high educational institutions, determination of the conceptual apparatus of the research; empirical – observation and analysis of the pedagogical phenomena and processes, collective and individual conversations with the aim of the revealing of the main contradictions and disadvantages within the education, within methods and educational processes for the detection of the students' understanding of the informational means of teaching, oriented on the increasing of their informational culture. Within the article, there were also determined the criteria of the informational culture of the future primary school teacher: informational activity, informational consciousness, informational-communicative readiness, informational thinking, and informational readiness. It is proved that the increasing of the informational culture of the future specialist for the primary school is able to become such an instrument which would give the opportunity to improve simultaneously the quality of the education and to become the environment and to provide the environment within which the new culture of teaching would be able to develop in. The strategic goal of the development of a system of increasing the qualification of the pedagogical staff foresees the augmentation of the openness and accessibility of the educational services and orientation on the individual demands of each student.


Objective To know the influence of out-hospital nursing with no gap on the level of HbAlc for patients with diabetes.Methods Divided 80 patients with diabetes into the intervention group and control group randomly,there were 40 cases in the each group.Out-hospital nursing cares with no gap were used in the intervention group,while the routine nursing cares were used in the control group.Fellowed up 1 year.Compared the FPG,2 hPG and HbAlc between the two groups at the time points of the 3rd,6th,9th and 12th month when out of hospital.Results All the indexes which had monitored were better in the intervention group than those of in control group.Conclusions Out-hospital nursing with no gap can remain the indexes in the normal level,and then promote their quality of life,which should be developed in clinical field.

Key words:
Diabetes; Out-hospital nursing with no gap; HbAlc


DB AG has adopted the Network 21 investment programme in order to streamline and modernise the infrastructure network. Balance sheet and income statement demand a balanced operating result. This is why the Corridor-based Purchasing strategy has been developed: it takes due account of this objective and contributes to cost reductions in the fields of operations management, maintenance and depreciation when investments are to be decided upon. Investments are put out to tender and commissioned at corridor and technical area level. The corridor may be an entire line or a defined network area. All planning and construction activities to be commissioned are assigned to a certain technical area, e. g. bridges / viaducts, command/control technology, and are commissioned simultaneously. In determining the sequence of the individual sections of line, the respective on-site conditions need to be taken into account. Both for planning and for construction, the entire cost reduction potential has to be identified and utilised. Reference to the balance sheet and the income statement is ensured through the life-cycle costs of buildings and plant and equipment or by means of balance sheet-oriented target costs. The corridor constitutes a profit centre. From its proceeds and costs, target costs are derived which the contractor, according to a binding stipulation on the part of DB AG, must not exceed. Procedures and contracts are optimised and directed towards this goal. In addition to prices, life-cycle costs will also be taken into consideration in future in the evaluation of offers and will be incorporated in the orders. The Corridor-based Purchasing strategy is already being tested on certain pilot lines.


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, An 83-year-old male presented to our outpatient clinic with complaints of sudden bilateral pain in the scapular girdles, hip pain, low-grade fever

https://reu.termedia.pl/pdf-155976-85351?filename=Is the absence of.pdf


Recently, benefiting from the advances of the deep convolution neural networks (CNNs), significant progress has been made in the field of the face verification and face recognition. Specially, the performance of the FaceNet has overpassed the human level performance in terms of the accuracy on the datasets "Labeled Faces in the Wild (LFW)" and "Youtube Faces in the Wild (YTF)". The triplet loss used in the FaceNet has proved its effectiveness for face verification. However, the number of the possible triplets is explosive when using a large scale dataset to train the model. In this paper, we propose a simple class-wise triplet loss based on the intra/inter-class distance metric learning which can largely reduce the number of the possible triplets to be learned. However the simplification of the classic triplet loss function has not degraded the performance of the proposed approach. The experimental evaluations on the most widely used benchmarks LFW and YTF show that the model with the proposed class-wise simple triplet loss can reach the state-of-the-art performance. And the visualization of the distribution of the learned features based on the MNIST dataset has also shown the effectiveness of the proposed method to better separate the classes and make the features more discriminative in comparison with the other state-of-the-art loss function.


Genetic studies in women of Hispanic/Latina origin identified a single nucleotide polymorphism (SNP) in the 6q25 region, rs140068132, that correlates with Indigenous American (IA) ancestry and is protective against BC. The underrepresentation of Latin American populations in public databases has hindered the study of the mechanisms by which this SNP confers a protective effect. We aimed to identify IA germline variants associated with BC risk and to test their association with tumor gene expression in this region.
 We performed a case-control fine-mapping analysis in the 6q25 region. BC patients part of the PEGEN-BC Study (N=1809) were included as cases and women from a pregnancy outcomes study in Peru as controls (N=3334). Genome-wide genotype data were available and missing genotypes were imputed using the TOPMED Imputation Server. Logistic regression was used to test the association between each SNP and BC risk. We exome-sequenced 247 breast tumors of PEGEN-BC patients. Tumor subtype was assigned by the pam50 method. We excluded patients diagnosed with stage IV disease, with tumors classified as normal-like or as uncertain, and carriers of the GG genotype for rs140068132, leaving 242 samples. Association between rs140068132 and gene expression of genes in the 6q25 region was tested adjusting by age at diagnosis and IA ancestry.
 The strongest signal corresponded to rs140068132 (odds ratio (OR)=0.53, p=1.9e-21). The model adjusted by rs140068132 revealed three additional independent variants that correlate with Indigenous American ancestry: rs184135739 (OR=0.8, p=0.006), rs141057867 (OR=0.87, p=0.006) and rs140125124 (OR=1.23, p=0.015). Gene expression analysis stratified by subtype revealed that among HER2+ tumors (N=63), rs140068132 was associated with ARMT1 (fold change comparing AA to AG (FC)=1.6, p<0.01), CCDC170 (FC=1.8, p<0.01), MTHFD1L (FC=0.7, p<0.01) and RMND1 (FC=1.4, p=0.013). Among Luminal-B (N=68) tumors, there was an association with ARMT1 (FC= 1.9, p=0.001), ESR1 (FC=1.4, p=0.04) and MTHFD1L (FC= 0.8, p=0.02). Only ESR1 was associated with the SNP (FC= 0.5, p= 0.03) among basal tumors (N=56). No association was identified among Luminal-A tumors (N=55). rs141057867 showed evidence of cis-association with CLDN20 (FC=1.4, p=0.014) among HER2+ subtypes and rs184135739 with ZC3H12D (FC=2.1, p=0.02) and SUMO4 (FC=1.8, p=0.023) among Lumina-A tumors.
 Two of the three novel IA SNPs are protective against BC and show association with gene expression. The rs140068132-G variant regulates the expression of genes in the 6q25 region in a subtype-specific manner. A possible mechanism explaining the protective effect of the rs140068132 polymorphism might be linked to the lower expression of MTHFD1L among G-allele carriers in some subtypes. This gene is deregulated in cancer and its expression is negatively associated with cancer survival, including BC.
 Citation Format: Valentina A. Zavala, Xiaosong Huang, Sandro Casavilca-Zambrano, Jeannie Navarro-Vásquez, Carlos A. Castañeda, Guillermo Valencia, Zaida Morante, Monica Calderon, Julio E. Abugattas, Henry Gómez, Hugo Fuentes, Ruddy Liendo-Picoaga, Jose M. Cotrina, Katia Roque, Jule Vásquez, Luis Mas, Marco Gálvez-Nino, Jovanny Zabaleta, Tatiana Vidaurre, Laura Fejerman. Regulation of genes located in 6q25 by an Indigenous American genetic variant in breast cancer patients from Peru. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 5237.


As an effective method for power system forecasting-aided state estimation (FASE), the unscented Kalman filter (UKF) based on correntropy has been widely used in recent years, ensuring the safe and reliable operation of power systems. In this article, to address the impulsive noise, Laplacian noise, bad measurement data, and sudden load change, a robust UKF algorithm based on generalized maximum mixture correntropy (GMMC-UKF) criterion is proposed for FASE, in which the kernel is composed of two generalized Gaussian functions. Specifically, we use a statistical linearization technique to unify the state error and measurement error in the cost function and obtain the optimal value of state estimation by fixed-point iteration. The effectiveness of the proposed algorithm for FASE is verified on IEEE 14-, 30-, and 57-bus test systems under a variety of abnormal situations. Compared with traditional correntropy algorithms, the GMMC-UKF shows more accurate estimation and stronger robustness.


The influence of anthropogenic and natural factors on the content of lead in the surface horizons of coastal soils and bottom sediments in the south of the Kamchatka Territory was studded. It was revealed that no significant excesses of acid-soluble forms of lead were found, however, a gradual increase in the content of this element in urban soils is observed. The most likely reason for the content of lead in the soils of this area can be considered pyroclastic material, which prevails in the composition of fine earth.


In order to solve the fine-grinding graduation problem, the serial cyclone is taken as the graduation equipment in circulation of grinding-graduating, then the grinding density and efficiency are enhanced greatly, the size fraction of -0.043mm for magnetite is achieved, and a high quality iron concentrate production is obtained successfully.


This study aims to expose the history of Islam in Ketapang by referring to Tujuh and Sembilan sacred tombs and narrating the reception (in the living al-Quran) of the community on the grave and its elements (part of the Quranic text, motifs, and others). This research is field research, using a narrative-analytic model, as well as using a historical approach and the living Quran theory (on reception). The results of this study are: 1) The history of Tujuh and Sembilan sacred tombs are the tombs of pious people who spread Islam in Ketapang around the 14th century A.D. Second, the typology of people's reception in the sentence kullu nafsin dzaiqatul maut is represented in three forms of reception, namely, hermeneutical or exegesis reception, aesthetic reception, and functional reception.


This article deals with the importance and difficulty of implementing and enforcing human rights values, standards, and norms to protect people from abuse by state institutions. The responsibility of the state in maintaining order and implementing the rule of law is acknowledged. This is then extended to one of the state agencies charged with the maintenance of public order: the police. Police compliance with human rights standards is imperative if human rights are to be protected. This article discusses what police compliance with certain rights could entail. This is followed by a look at the role of the police in society and the societal and institutional realities that impede the implementation of police human rights strategies in Latin America. The implementation of these strategies have sparked debates on the implementation of human rights, inequality, security, and the hurdles to police reform in Latin America.


Ice platforms are engineered sheets of floating ice that are designed to support long-term stationary loads, usually related to construction. These loads can include cranes, drill rigs, excavators, girder trucks, and tandem trucks. This paper will discuss general design procedures for ice platforms as well as cases with special considerations such as multiple long-term loads, repetitive long-term loads, objects dropped down onto the ice, loads near large holes in the ice, loads near bridge piers, loads near banks, and loads on access ramps.


The purpose of the study was to find the determinants of e-learning implementation by teachers of vocational school in the Yogyakarta Special Region. The research objective was achieved by describing the essential influence of social environment and facilitating conditions toward the technology acceptance model of e-learning. The study was a correlational research one with an ex-post facto approach. The number of research sample was 132 teachers and the research sample was determined by the Krejcie & Morgan formula. The research sample was distributed by means of proportional random sampling technique. The primary data source was the teachers' self report which had been collected by using a questionnaire. The observation and the open-ended interviews were conducted in order to support the primary data. The content validity was assessed by means of expert judgment and the construct validity was calculated by means of Pearson correlation. The reliability was determined by means  of Cronbach's Alpha minimum value namely 0.70. The data analysis was performed by  using path analysis at a significance level of 0.05. The study concluded that the effect of social environment and facilitating conditions to the e-learning usage had been mediated by three main variables of Technology Acceptance Model (TAM), namely perceived usefulness, perceived ease of use, and intention to use. Keywords : E-learning, technology acceptance model, social environment, facilitating conditions. DETERMINAN PENGGUNAAN E-LEARNING OLEH GURU SMK DI DAERAH ISTIMEWA YOGYAKARTA Abstrak Studi ini bertujuan untuk mengetahui faktor determinan penggunaan e-learning oleh guru SMK di Daerah Istimewa Yogyakarta. Tujuan ini dicapai dengan cara menjelaskan hakikat pengaruh lingkungan sosial sekolah dan kondisi fasilitas teknologi terhadap model penerimaan teknologi e-learning. Studi ini merupakan penelitian korelasional bersifat ex-post facto. Sampel penelitian sebanyak 132 guru ditentukan menggunakan formula Krejcie & Morgan didistribusikan dengan teknik proportional random sampling. Sumber data primer adalah laporan diri guru, dikumpulkan menggunakan kuesioner. Observasi dan wawancara terbuka dilakukan sebagai pendukung data primer. Validasi isi dilakukan dengan expert judgment  dan validasi konstruk dilakukan dengan korelasi Pearson. Reliabilitas ditentukan dengan dengan nilai Cronbach's Alpha minimal 0,70. Analisis data dilakukan dengan analisis jalur pada taraf signifikansi 0,05. Hasil studi menunjukkan pengaruh lingkungan sosial dan kondisi yang memfasilitasi terhadap penggunaan e-learning dimediasi oleh tiga variabel utama model penerimaan teknologi, yaitu kegunaan, kemudahan penggunaan, dan intensi. Kata kunci : e-learning, model penerimaan teknologi, lingkungan sosial, kondisi yang memfasilitas


:- A Pellet stove is Mechanical Device which uses compressed wood or biomass pellets to create a source of heat for residential and industrial spaces [6]. These stoves are electronically sophisticated appliances that offer an environmentally friendly and low-cost heating option. Its Fuel consists of wood chips, waste of nuts, grasses, and lumber yard waste. The Pellets which are filled in the combustion chamber is then ignited [3]. Pellets are heavily compressed, so they're dense and low in moisture, creating a hotter flame. The combustion chamber serves as the carburettor for the stove, mixing the air and fuel to create combustion. The ashes from the burnt pellets are captured in an ash pot, which needs to be cleaned periodically. Wood pellet stoves are generally small, and the bags of pellets are about the size of a mulch bag, making them easy to store. They're also easy to operate; they only require loading pellets and igniting the flame. Because the fire is contained in a heat box inside the unit, there is a minimum of smoke, which lessens the smell in your home and prevents the outside of the unit from heating up. Pellets create considerably less ash than firewood [5], giving off less creosote, a flammable by product of combustion that can build up and cause chimney fires.


The structure of the synthetic, protected peptide Z-(Aib) 6 -OBu t (C 36 H 58 O 9 N 6 , M w = 718.89) which contains the conformationally constrained residue α-aminoisobutyric acid (Aib) has been determined by X-ray crystallography. The title compound crystallizes in P2 1 /c with a = 8.992(4) A, b = 19.382(4) A, c = 27.451 (10) A, β = 115.63(4)°, V = 4360.5(8) A 3 , Z = 4, D x = 1.14(2) gcm −3 . The final R after refinement is 0.088 for 5221 observed reflections. The hexapeptide adopts a 3 10 helical conformation with a reversal of the sense of the helix at the C-terminal Aib residue


The conflict between China's urban expansion and agricultural land loss, in terms of food security versus achievements in economic development, are currently widely discussed. Based on GIS/RS techniques and multivariate linear regression models from a multitemporal perspective, rapid urbanisation in the study area could mitigate the shrinking availability of arable land, whereas land protection policies have had no obvious effect. GDP and urbanisation are the main drivers of the expansion of the non-agricultural land. The original role of agriculture in urban development cannot be neglected, although it contributes very little to a city's economic growth, and could prove to be a potential obstacle to sustainability of urban development.


Summary
Soil samples collected from approximately 1700 fertilizer trials carried out around 62 centres in Uganda were analysed. Mean levels of total N. organic P and cation exchange capacity at the 60 centres which had non-volcanic soils were very closely related to mean organic matter levels and largely explained the strong correlation of indices of available N, P and base status with organic matter. The indices of available P and base status were additionally related to pH and the indices of available N and P were further negatively correlated with sunshine hours.

Soil organic matter itself was closely related to the content of clay, silt and free Fe. with which it is presumed it forms a stable complex, whilst soil pH decreased with rainfall in excess of evaporation. Thus soil texture, rainfall and hours of sunshine are the basic factors which largely determine inherent soil fertility in Uganda.


The goal of this chapter is to provide the reader with general information on several key features of behavior genetic investigation. The chapter starts with a general introduction of what genetic material consists of and how it is transmitted from parents to offspring. An understanding of inheritance is vital for understanding basic and commonly used statistical methods of gene-behavior association. We discuss the concept of a normal distribution of measured behavioral traits and of unmeasured (latent) genetic and environmental liability. We introduce and provide examples of models of twin resemblance commonly used to estimate the relative contribution of genetic and environmental factors on individual differences in behavior, and of models that examine the association of measured genetic variation and behavior. We discuss the importance of behavioral measurement and underscore its complexity throughout the chapter. We conclude with discussion on ethical issues in genetic research.

Keywords:

complex behavior;
twin models;
genomic models;
phenotype


In a response to Gill Kirkup's questioning of how to fund digital scholarship, Martin Weller argues that current publishing economic models are not sustainable in a digital world and tackles the funding questions that surround open access publishing, scholarship and education.


Shoot-root ratio (S:R), dry matter partitioning (DMP), and water use efficiency (WUE) response of wheat (Triticum aestivum L.) vs. rye (Secale cereale L.) was investigated under organic [organic compost (OC), Miracle Grow (MG), sunshine peat moss (SPM), and Garden Basic peat humus (GBPM)], and inorganic soils [canyon soil (CS) and amarillo soil (AS)] in pot experiment at Dryland Agriculture Institute, West Texas A&M University, College Station, Texas, USA, during winter 2009–2010. The experiment was performed in completely randomized design (CRD) with three repeats. The objective of this experiment was whether S:R, DMP, and WUE of wheat versus rye differ under organic and inorganic soils. The results revealed that both crops responded differently in terms of S:R, DMP, and WUE under different organic and inorganic soils. Wheat had higher WUE than rye at different growth stages. Among the soil types, the three organic soils (MG, SPM, and GBPS) had higher WUE than the two inorganic (CS and AS) soils. The higher WUE of both crops when grown in organic soils such as MG, SPM, and GBPS was due to the higher dry matter partitioning to shoots and roots. The total dry weight plant−1 showed positive relationship with WUE.


This article presents highly-efficient and inexpensive ripple-free resonant neutral-point-clamped (NPC) dc–dc converter that does not use extra inductors. By using the push–pull transformer itself, with the primary-side switching modulation fixed at 0.5, the proposed converter accomplishes theoretically zero input current ripple. Because of the resonant NPC cell, the circuit does not experience instantaneous reactive current flow regardless of wide input voltage variation. The resonant NPC structure much reduces the voltage stress at the turn-off instant; this aspect enables use of inexpensive low-voltage-rated active power components. Therefore, the proposed converter is inexpensive, highly efficient, and has high power density. A 1-kW experimental prototype was implemented and it was tested to validate the superior properties of the proposed converter.


The issue of possible non-linearities in the relationship between log wages and schooling has received a good deal of attention in the literature on the United States, as well as in Less Developed Countries (LDCs). In this paper, I use data from a recent household survey for the Philippines, the 1998 Annual Poverty Indicator Survey (APIS), to test the fit of the log-linear specification for Filipino men. I present results based on a number of estimation strategies, including discontinuous spline regressions, semi-parametric regressions with a large number of dummies for years of schooling and experience, and kernel regressions. The basic conclusions of the paper are two. First, there appear to be large differences between the rates of return to education across levels in the Philippines. In particular, the wage premia to both primary and secondary education are lower than those for tertiary education. Second, within a given level, the last year of schooling is disproportionately rewarded in terms of higher wages. That is, there are clear sheepskin effects associated with graduation from primary school, secondary school, and university. * Economist, East Asia and the Pacific, Poverty Reduction and Economic Management, The World Bank. 1 I would like to thank Harold Alderman, Ruperto Alonzo, Benu Bidani, Gaurav Datt, Olivier Deschenes, Emanuela Galasso, Hans Hoogeveen, Emmanuel Jimenez, Homi Kharas, Erzo Luttmer, Tamar Manuelyan Atinc, and Lant Pritchett for many useful comments and conversations. Please address correspondence to the author at email@example.com. The views and interpretations expressed in this paper are those of the author and do not necessarily represent the views and interpretations of the World Bank, its Executive Directors, or the countries they represent.


Piezoelectric copolymer, PVDF-TrFE, diaphragm arrays with integrated microfluidic chip for high performance protein immunosensors were developed and characterized in this work. Mold-transfer and hot-embossing techniques provide a high throughput and repeatable way to fabricate piezoelectric polymer diaphragms and PVDF-TrFE's hydrophobic surface acts as a natural bioreceptor to capture proteins of interest. In addition, integrated microfluidic devices enhance reaction efficiency and reduce the assay time.


Camcorders today are no longer considered simple tools that allow us to digitally capture unforgettable moments and memories. These devices, currently, are being used by different entities, companies, institutions and individuals to control and monitor under a physical security management system that gives them a clarity of the existing landscape around them, as well as obtaining clear evidence that compromise their reputation and identification of internal or foreign individuals to them. The analysis of the present project evaluated to reveal the causes of the main problem in the face of the imminent growth in the number of university students who copy during the development of online exams. In accordance with the aforementioned, in this research project we propose the use of advanced image analysis that through learning models manage to detect suspicious behavior pat-terns in real time that will alert students in case of plagiarism.


This paper presents an interactive graphics package for distribution system analysis. The radial operation of the distribution networks is exploited in order to effect a fast and accurate calculation of the power flows, the voltage drops and the power losses at the various segments of a feeder for a given set of typical load curves. The algorithms developed are based on an efficient method to store the network topology and can easily accommodate changes in the infeeding nodes and variations in the network structure due to switching operations. The interactive environment allows the user to obtain the results of his studies against the one-line diagram of the network and effect changes in it in basically diagrammatic terms. The package requires very modest computer resources and provides planning and operating engineers with a powerful tool to conduct analytical distribution system studies with ease and flexibility.


The aim of the MITHRA project is the design of an autonomous mobile robot for survey and teleoperating. This project groups several european partners. The role of LIFIA was to design the man machine interface and the navigation control system. The architecture of such system can be described in terms of layers of control, from effectors and sensors level to the symbolic level. At this level there are two modules which communicate with each other: the supervisor and the Man Machine Interface (MMI). This paper describes these two modules. The MMI allows a human operator to describe the robot environment, describe the missions and monitor their execution. For this novice operator, we defined a mission specification language which contains, in a very simple formalism, all the concepts needed for a description of a mission such as time, resources and tactical constraints. The supervisor module plans the mission and during this phase the operator can interact with the supervisor to modify the mission and simulate the execution of the mission. During the execution, the supervisor monitors the constraints and can decide to replan the mission in case of any constraint violation or execution failure. The operator doesn't necessarily step in but he can stop the execution at any time to add or retract a task or teleoperate the robot. Another functionality of the MMI is to replay the executed mission with his historic file. We will discuss the model chosen for the MMI and the role of the supervisor in the dialog between the operator and the remote system. Finally, we will show examples of the working system.


Sonographic prediction of macrosomia cannot be improved by combination with pregnancy-specific characteristics Balsyte D, Balsyte D, Schäffer L, Burkhardt T, Wisser J, Kurmanavicius J. Ultrasound Obstet Gynecol 2009; 33: 453–8. We all know how inaccurate fetal weight estimation at ultrasound examination can be. So a search for help in increasing prediction accuracy is reasonable. This study, however, concludes that ultrasound is still the best and most objective method currently available to estimate birth weight in an unselected population. In fact its best function may be to exclude macrosomia and prevent unnecessary interventions.


This review of activity learning in mathematics covers publications from January 1964 through December 1968. In the context of this article activity learning is taken to mean school learning settings in which the learner develops mathematical concepts through active participation. This process may involve the manipulation of physical materials, the use of games, or partaking in experiments with physical objects. Theory and research on the effects of this type of activity will be discussed in this article under manipulative learning.


UML is an important application of Object-Oriented technology, and is also a useful object analyzing and designing tool in modern software engineering. After introducing modeling principle of UML, this paper introduces a particular application of UML technology in combination with analyzing and designing process in the project of Haikou voice invoice query system.


From the topological angle and byintroducing the definitions of continuous mapping,open mapping,closed mapping,homeomorphic mapping,submatroid and quotient matroids,under which the qualities of matroids are studied,and some equivalent condictions are obtained.Inadditional,whether the independent set,dependent set and circuit of matroids are held under these mappings is discussed.


We study the problem of finding K collision pairs in a random function f : [N] → [N] by using a quantum computer. We prove that the number of queries to the function in the quantum random oracle model must increase significantly when the size of the available memory is limited. Namely, we demonstrate that any algorithm using S qubits of memory must perform a number T of queries that satisfies the tradeoff T3 S ≥ Ω (K3 N). Classically, the same question has only been settled recently by Dinur [22], who showed that the Parallel Collision Search algorithm of van Oorschot and Wiener [36] achieves the optimal time–space tradeoff of T2 S = Θ (K2 N). Our result limits the extent to which quantum computing may decrease this tradeoff. Our method is based on a novel application of Zhandry's recording query technique [42] for proving lower bounds in the exponentially small success probability regime. As a second application, we give a simpler proof of the time–space tradeoff T2 S ≥ Ω (N3) for sorting N numbers on a quantum computer, which was first obtained by Klauck, Špalek, and de Wolf [30].


Connie Chatterley,the heroine in D.H.Lawrence's last master piece Lady Chatterley's Lover,realizes her mental and physical rebirth through her choice between two men,who represent the industrial society's sexual repression and the expression of human natural sex instinct respectively.Since understanding the spiritual transition course of the heroine is the key to appreciating this novel's essence,this paper analyses Connie's mental world in every step of her dramatic marriage life.


Abstract A phosphate-selective electrode is developed based on a silver coordination reaction. The electrode responds linearly toward HPO4 = in the concentration range of 10−4 to 10−1 M (slope = 27 mV/dec.). The electrode also shows good selectivity over sulfate, nitrate, perchlorate and acetate.


The study objective was to examine the influence of exercise (EX) ancestry compared to sedentary (SED) ancestry on offspring skeletal muscle gene expression. C57/Bl6 mice (F0) were exposed to EX (wheel running, N=20) or a SED condition (no wheel access, N=20) for 12 weeks prior to breeding. EX males and EX females, and SED males and SED females were bred to produce F1 pups. F0 EX mice had continued access to the wheel during breeding, pregnancy, and weaning. F1 pups were sacrificed at 8 wk without direct exercise exposure. Microarray analysis of gene expression was performed on pooled gastrocnemius RNA from F1 males of each ancestry (5 animals per array; 4 total arrays). After processing the microarray data to minimize false positives, 109 transcripts were differentially expressed between F1 EX and F1 SED. Three targets identified as upregulated in F1 SED offspring have been previously associated with lipogenesis and were selected for real‐time PCR validation (Adipoq, Scd1, and Cidec). Adipoq and Scd1 were verified as significantly upregulated in F1 SED offspring (p < 0.05) and Cidec tended to be upregulated in F1 SED offspring (p = 0.06). These preliminary findings indicate that exercise ancestry (i.e., parental exercise stimulus) can affect lipogenesis‐related skeletal muscle gene expression in male mouse offspring.


Introduction Discriminating injuries by animal attacks from other types of trauma and assessing their contribution to the cause of death is often difficult. Careful evaluation of the injury pattern, thorough scene examination and performing adequate ancillary investigations is essential in such situations. Case report A young male was found dead in a hut in a chena, lying in a pool of blood with a shotgun beside him. There was a suicide note on the floor written with charcoal which indicated that he had encountered three bears in the jungle, fought and escaped with injuries. Autopsy revealed minimal damage to the clothes and to the body. There was a near contact entry wound under the chin. Shaving of the head hair revealed a star shaped entrance wound with burning and blackening on the vertex. An exit wound with extensive disruption of the left side of face was seen. CT scan confirmed the above findings. The manner of death was concluded as a homicide. Conclusion Minimal damages to the clothes and other areas of the body exclude bear attack with a high probability. Even though entry under the chin is more suggestive of suicidal firing, the entry at the vertex favors the involvement of another person.


Green tea contains considerable amounts of epigallocatechin‐3‐gallate (EGCG), epigallocatechin (EGC), and epicatechin (EC). EGCG has already been shown to exhibit anti‐inflammatory activity. Pro‐inflammatory cytokine interleukin‐1β (IL‐1β) produced by monocytes and macrophages plays an important role in rheumatoid arthritis (RA). In this study, we compared the efficacy of different catechins in reducing the inflammatory response to IL‐1β in human RA synovial fibroblasts (RA‐FLS).


Sports video processing is an interesting topic for research, since the clearly defined rules in sports provide a limited, controlled environment. Moreover, it is interesting because many specialized applications for sports video processing are emerging. This paper gives an overview of sports video research, where we describe basic algorithmic techniques as well as applications.


BACKGROUND:Using a rat L5 spinal nerve transection model we previously showed that pentoxifylline prevents hyperalgesia through antiinflammation in the prefrontal brain. In this study, we examined efficacy when applied after injury. METHODS:We examined the effect of pentoxifylline on existing mechanical allodynia, observing glial activation and proinflammatory cytokine expression in the lumbar spinal cord, when given 7 days after L5 spinal nerve transection. RESULTS:There was no effect from pentoxifylline on existing hypersensitivity, glial activation, and cytokine expression when applied after L5 spinal nerve transection. CONCLUSION:Pentoxifylline administered intraperitoneally on day 7 postsurgery failed to alleviate existing hypersensitivity, or reduce glial activation and cytokine expression.


A dividable frequency band is widened without performing variable control of a load circuit. A master stage (101) comprises a differential circuit including a transistor (1) and a transistor (2), a differential circuit including a transistor (3) and a transistor (4), a differential circuit including a transistor (5) and a transistor (6), a load circuit (7) (first load circuit), a load circuit (8) (second load circuit), and a current source transistor (9). The load circuit (7) (first load circuit) includes an inductor (7A) (first inductor), an inductor (7B) (fifth inductor), and a capacitor (7C) (first capacitor). The inductor (7B) and the capacitor (7C) constitute a parallel resonant circuit (first LC parallel resonant circuit), which is connected to the inductor (7A) in series.


The quality of visual image in an autostereoscopic 3D display was found for case of multiple observer regions. This was made in the projective coordinates for which the forward and backward transformation matrices were found. It was demonstrated that the quality is kept along the nodal lines in all regions as well as between them. The distinctive locations were found together with the exact values of the quality function in these points. This allows estimating the behavior of the quality function for bigger number of views and image cells as well as across the longer and wider area.


NM450 (450 HBW-grade, low-alloy, wear-resistant steel) is an ultrahigh-strength steel, in most cases, the inclusions in NM450 have a negative effect on its toughness, strength, and weldability. However, the detrimental effect of inclusions can be reduced by inclusion modification. In this study, the effect of oxide metallurgy on the evolution of inclusions in NM450 ultrahigh-strength steel was investigated, and it was found that as the O content increased in the steel before treatment, the Ti content in the formed inclusions increased. By extending the deoxidation time after adding Ti, the ratio of inclusions smaller than 10 μm in the steel increased, whereas that of larger inclusions gradually decreased. In the Ti–Ce and Ti–Ca composite deoxidation, the former had a higher and more stable yield, but the Ca treatment was more conducive to the nucleation of sulphides, thus reflecting the oxide metallurgical effect. The addition of Ce was prone to adhesion to the crucible wall, which may have an adverse effect on actual production. This work provides a theoretical reference for broadening the scope of application of high-strength steel products, improving product quality.


Background: It has become apparent that while apoptosis occurs in the heart after myocardial infarction, more cells die by necrosis, which we and others have recently shown can be a regulated process. Defining the molecular mechanisms underlying programmed cellular necrosis may thus offer novel treatment strategies for cardiovascular disease and other cell death-driven disease processes. Methods: To identify novel molecular effectors of programmed necrotic cell death we developed a functional cell-based assay to quantitate plasma membrane rupture (a hallmark of necrosis) in conjunction with a high-throughput, robotic-based screen using an shRNA total genome library in lentivirus. This library consists of over 77,500 clones targeting more than 16,000 genes in the mouse genome (~5 clones/gene target) to enable loss-of-function screening in a 96-well format. Results: We identified hundreds of shRNA clones that enhanced membrane rupture (protective gene targets), as well as hundreds of shRNA clones that inhibited membrane rupture (pro-necrosis gene targets). Using bioinformatic enrichment analyses and gene ontology grouping, a novel and interesting pathway emerged that was associated with the SNARE-complex and genes affecting membrane fusion events. Secondary screening with a custom SNARE pathway library of 350 lenti-shRNAs targeted against 66 genes confirmed a prominent role in programmed necrosis initiated by a variety of death-inducing stimuli. Indeed, knockdown of select genes in this membrane fusion/SNARE pathway ameliorated programmed cellular necrosis in vitro. Summary: These findings suggest membrane fusion/SNARE complex pathways as a novel biological component of programmed necrosis and provide an entirely new therapeutic strategy for reducing cell death in the heart following myocardial infarction injury.


As lithography pushes to smaller and smaller features under the guidance of Moore's Law, patterned features smaller than the wavelength of light must be routinely manufactured. Lithographic yield in this domain is directly improved with the application of OPC to the pattern data. However, such corrections generally assume that the reticle can reproduce the benefits of OPC in some circumstances. In this paper, we present the characterization of the MEEF for contact holes. These are found to have significantly higher values for the MEEF than typically measured for isolated lines. Theoretical predictions are compared with experimental results. Good agreement is found at the center of the field only when the actual area of the contact hole as formed on the reticle is used as the metric of contact size. Across field variation, however, is found to be significant requires characterization for optimum yield to be achieved.


Nitrate reductase (NR) and phospholipids were immobilized on gold electrodes with 2_aminoethanethio(AET) SAMs. After Au/AET/NR and Au/AET/NR/lipid were soaked in pH 7 phosphate buffers for days,a pair of pre_reversible peak appeared at around 0.202 V and 0.149 V,respsctively, irregularly grew with soaking time in blank buffer.The cathodic peak current(i pcl )of Au/AET/NR system had linear relationship with scan rate between 0.02 and 0.5 V.s -1 ,while i pcl was proportional to V 1/2 in Au/AET/NR/lipid system.The direct electron transfer of enzyme electrodes was strongly affected by pH.Compared with Au/AET,NR exhibited a higher electrochemical activity in Au/AET/lipid system.


Recently, the importance of a lived experience workforce in the delivery of mental health services has been demonstrated. The roll-out of the National Disability Insurance Scheme (NDIS) in Australia has generated the need for a significant increase in the disability workforce, including psychosocial disability. The purpose of this paper is to describe the strategies outlined in the One Door Mental Health Lived Experience Framework (LEF), which is the culmination of over 30 years of experience in providing mental health services and the employment of a lived experience workforce.,One Door developed and implemented the LEF, a thorough guide to the employment and support of a workforce of people with lived experience of mental illness, through consultation with consumers, carers, stakeholders, practice advisors, management, human resources and employee focus groups.,Extensive support structures in the LEF are key to achieving the benefits of a lived experience workforce. The LEF has positioned One Door successfully for the achievement of key organisational goals in mental health support and advocacy.,Mental health policies and support are critical for productivity outcomes in any workplace regardless of the level of lived experience of the employees. This paper provides organisations, particularly those within the mental health sector, an example to build on in their own employment and support strategies.,This paper is of particular value in the context of organisations in the mental health sector transitioning to the NDIS.


This paper presents a method of optimizing real and reactive power in Power Systems. A comparative study is made on simultaneous and sequential optimization of real and reactive power subproblems. For active power optimization generator real power outputs are taken as control variables and cost minimization is the objective. For reactive power optimization generator bus voltages, shunt capacitors/reactors, and transformer tap positions are taken as control variables while cost minimization/loss minimization is taken as objective. For simultaneous optimization of both the subproblems are formulated as cost minimization problem. Particle Swarm Optimization method is used for solving this complex, non-linear, non-convex optimization problem. Simulations are carried out on standard IEEE 30 bus system and results are presented.


AIMS
Limited data are available on the changes that occur at the dilated site many years after coronary balloon angioplasty. The development of bioabsorbable stents may increase the importance of understanding the long term changes that occur in an unscaffolded coronary artery following balloon-mediated injury.

METHODS AND RESULTS
This study evaluated, by serial quantitative angiography, the natural history of changes that occurred in the dilated segment between early (mean seven months), late (mean 4.5 years) and very late (mean 17 years) follow-up after balloon angioplasty. Of 127 consecutive patients (174 lesions) with successful coronary angioplasty, 125 underwent early, 84 late and 47 very late angiographic follow-up (75% of eligible survivors). The mean lesion diameter stenosis decreased from 36+/-11% at early to 26+/-15% at late follow-up (p<0.0001), and then increased again to 35+/-25% by very late follow-up (p=0.003). Although stenosis severity at early follow-up angiography predicted lesion regression at late follow-up, there was no significant correlation between late and very late follow-up lesion severity.

CONCLUSIONS
After coronary angioplasty, lesion regression at the dilated site from 7 months to 4.5 years is followed by slow lesion progression over the next 12 years.


Smoke aerosol plumes generated during the biomass burning season in Brazil suffer long-range transport, resulting in large aerosol optical depths over an extensive domain. As a consequence, downward surface solar irradiance, and in particular the direct component, can be significantly reduced. Accurate solar energy assessments considering the radiative contribution of biomass burning aerosols are required to support Brazil's solar power sector. This work presents the 2nd generation of the radiative transfer model BRASIL-SR, developed to improve the aerosol representation and reduce the uncertainties in surface solar irradiance estimates in cloudless hazy conditions and clean conditions. Two numerical experiments allowed to assess the model's skill using observational or regional MERRA-2 reanalysis AOD data in a region frequently affected by smoke. Four ground measurement sites provided data for the model output validation. Results for DNI obtained using δ-Eddington scaling and without scaling are compared, with the latter presenting the best skill in all sites and for both experiments. An increase in the relative error of DNI results obtained with δ-Eddington optical depth scaling as AOD increases is evidenced. For DNI, MBD deviations ranged from −2.3 to −0.5%, RMSD between 2.3 and 4.7% and OVER between 0 and 5.3% when using in-situ AOD data. Overall, our results indicate a good skill of BRASIL-SR for the estimation of both GHI and DNI.


Procedures for estimating the composition of a fixed population from a small sample are often required but generally are not available in ordinary statistical texts. This paper considers the even more unique case where a particular condition is observed for all members of a sample. Formulas for estimating sample size and population composition are given.


Objective:To compare dosiology of different radiation therapy plans for rectal cancer.Methods: Respectively design three-dimensional conformal radiation therapy and intensity modulated radiation therapy for eighteen patients who suffering from rectal cancer.Dose volume histograms were used to compare the target volume and organs at risk.Results: Intensity modulated radiation compared to three-dimensional conformal radiation therapy,there were significant differences in Dmean(P0.05).Dmean of intensity modulated radiation therapy was more close to the prescription dose,conformity index and homogeneity index more close to one,compared to the three-dimensional conformal radiation therapy,the small intestinal's D30%,Dmean,Dmax and bladder's D30%,D50%,Dmean were reduced,the small intestinal's D50% and the femoral head's D5%,Dmean were higher,but still lower than the dose equivalent limits.Conclusion: Intensity modulated radiation therapy in the treatment of rectal cancer,the CI,HI,organs at risk of target is better than three-dimensional conformal radiation therapy.


The XBRL report is to establish the beginning of the standardization of accounting informationization in our country. XBRL report is in the accounting standards for enterprises under the premise of information disclosure of financial report. This paper attempts at standardization of accounting information system within the framework of research on accounting information standards, application of XBRL in our country enterprise financial management put forward some feasible Suggestions and related guarantee measures.


To acquire an information regarding the best travel destination, there are two main sources which can be used: advertising (books and magazines, TV, radio, and travel agencies) and word-of-mouth recommendations (WOM) via the Internet and friends. This study employed two research questions. First, how does advertising influence WOM, and vice versa. Second, to tackle the unsolved problem regarding how to predict traveler demand using WOM that can help improving tourism competitiveness. By using static demand and quadratic cost function, the authors found that advertising generates optimal outcome in tourism industry rather than WOM. Although the player's (the tourism industry in a country) net profit tends to have a positive effect on optimal advertising investment, it is the opposite case if WOM is used. WOM can be detrimental to an agent's advertising campaigns, and may create disadvantage on tourism competition. Type of Paper: Empirical


The aim of this document is to introduce acoustic signal processing in passive sonar system with towed array. The concept of the "acoustic signals processing" includes all possible operations on analogue signals such as amplifying, filtering, sampling and most importantly operations on digital signals obtained in the sampling process. Digital operations executed in the system include: synchronizing, conversion, sorting, creating deflected beams sets, plotting the power density spectrum received signals and imaging the results. Apart from digital signals processing, we focus on reciprocal connections between microcontrollers and processors in which processing is performed. At the end of this document some exemplary imagings of the output are presented, obtained at the marine testing of this system.


Abstract The research deals with improvement of methods and systems of controlling integrated power systems (IPSs) on the basis of intellectualization of decision-making support. Complex analysis of large-scale accidents at power facilities is performed, and their causes and damages are determined. There is substantiated topicality of building condition knowledge-bases as the foundation for developing decision-support systems in power engineering. The top priorities of the research include developing methods of building a knowledge base based on intensity models of control actions influencing the parameters of power system conditions and introducing the smart system into information contours of the automated dispatch control system (ADCS), as well as assessing practical results of the research. To achieve these goals, the authors apply methods of experiment planning, artificial intelligence, knowledge presentation, mathematical simulation, and mathematical statistics as well as methods of power systems studying. The basic research results include regression models of a power system sensitivity to control actions, methods of building a knowledge base based on the models of sensitivity matrices, a structure of the smart decision-support system, a scheme of introducing the decision-support system into the operating ADCS environment. The problem of building a knowledge base of the dispatch decision-support system on the basis of empirical data resulted from calculating experiments on the system diagram has been solved. The research specifies practical efficiency of the suggested approaches and developed models.


The intercommunications between the video devices using different standards are so much inconvenient, thus video codec suppor ting multiple standards are more useful and more attractive. In this brief, a low cost very large scale integration (VLSI) architecture is designed for multistandard inverse Discrete Cosine transform. It is used in multistandard decoder of MPEG-2, MPEG-4 ASP, and VC-1 .Two circuit share strategies, factor share (FS) an adder share (AS) are applied to the inverse transform architecture for saving its circuit resource. Pipelined stages are used in this Multistandard inverse transform to increase the operational speed.


We present an arbitrage-free affine term structure model that jointly prices U.S. Treasury bonds, S&P 500 dividend strips and the S&P 500 equity index as a function of the economy. Our model allows us to extract new insights on how short- and long-duration dividends and their discount rates respond to changes in the economy. Within the affine model, we obtain accurate decompositions of discount rates into risk free rates, inter est rate and dividend risk premiums. Our model is able to price bond and equity claims with high precision and predict economic variables and returns in bonds and short-horizon dividends.


We give an exact enumerative formula for the minimal acyclic deterministic finite automata. This formula is obtained from a bijection between a family of generalized parking functions and the transitions functions of acyclic automata.


The usage of actual reinforced thermoplastic composites for structural aircraft applications is very limited because materials with higher mechanical and physical properties are needed. In the recent years, aircraf t manufacturers have requirements for new continuous fiber reinforced thermoplastic composites with a significant improved performance/costs ratio for new, structural aircraf t applications. That is why a new affordable reinforced composite with a poly (phenylene sulfide sulfone) matrix, presenting high mechanical and thermal resistance properties, is introduced in this paper. Its process by thermopressing, which has been optimized to get the highest properties, is presented. Mechanical characterizations have been performed and microscopy analyses have also been achieved to control the internal structure of the c omposite. I. Introduction EROSPACE Industry is showing an increasing interest for high performance reinforced thermoplastic composites for structural applications in modern ai rcrafts 1 , with the goal of reducing weight and saving fuel consumption. Indeed, in the recent years, the appli cation of reinforced thermoplastic composites has c onsiderably increased: thus, composite materials make up 25% of the total weight of the A380's airframe (extensive ly in wings, fuselage sections, tail surfaces and doors). Boeing also uses a reinforced plastic fuselage for the pr oduction of the Boeing 787 Dreamliner, which consists of approximately 50% share of the total aircraft's weight. When in full production, with its 787 Dreamliner Boeing will bec ome the first to launch a full-size commercial airc raft with composite wings and fuselage. Since composites based on continuous carbon fibers embedded in high performance thermoplastic polymers were commercially introduced in the early 1980s, ad vanced thermoplastic matrix composites have been among the most attractive materials in the aerospace industry and other high-performance applications. Their com mon advantages include not only those of polymer matrix composites, such as high-specific modulus and stre ngth, but also characteristics that thermoplastics offer as m atrices, namely unlimited shelf life, recyclability , cost effective processing and excellent toughness 2 .


OBJECTIVE
To assess the safety and efficacy of adding intrathecal morphine to intrathecal ziconotide in patients treated with stable ziconotide doses.

DESIGN
Multicenter, open-label study with a 4-week morphine titration phase during which ziconotide was held constant and an extension phase during which dosing of either drug could vary.

SETTING
Outpatient clinics.

PATIENTS
Patients with suboptimal pain relief receiving stable ziconotide doses (> or = 4.8 microg/day) in one of two ongoing ziconotide trials.

INTERVENTIONS
Ziconotide dosing remained constant during the titration phase; intrathecal morphine titration was based on each patient's daily systemic opioid dose at the study's start. During the extension phase, intrathecal ziconotide and morphine dosing were adjusted per investigator discretion.

OUTCOME MEASURES
Safety was assessed primarily via adverse events. Efficacy was analyzed via percentage change on the visual analog scale of pain intensity and in weekly systemic opioid consumption.

RESULTS
Twenty-five patients enrolled. The most common (> or = 10% of patients in either study phase) study drug-related (i.e., ziconotide/morphine combination [or ziconotide monotherapy in the extension phase only]) treatment-emergent adverse events included dizziness, peripheral edema, pruritus, and nausea. From the initial visit to week 4, visual analog scale of pain intensity scores improved by a mean of 26.3% (95% confidence interval: 15.6%-37.1%) but varied during the extension phase (mean percentage change from the initial visit ranged from -0.4% at week 16 to -35.0% at week 72). Mean percentage decrease in systemic opioid consumption from the initial visit was 49.1% at week 4 and 51.2% at week 56 of the extension phase.

CONCLUSIONS
Intrathecal morphine, combined with stable intrathecal ziconotide doses, reduced pain in patients with previously suboptimal pain relief on ziconotide monotherapy.


The management case teaching can not achieve good effect without defining teachers'role accurately.The teacher has actedas the director,the spokesperson,the director,the catalyst and so on in the successful case teaching.In the management case teaching the teacher wants to pay attention to the teaching steps and the skills that preparation beforehe class,the classroom skill,completing the summary and the classification,he can locate the role accurately.


Among the archaic cosmologic and cosmogonic concepts of cultures worldwide and across time the metaphor of the world as a giant living entity is significant. People cultures considered the universe to be e.g. an animal, a giant human, or an egg. The anatomy of certain creatures, in particular of the human being, served as an excellent model for the world"s spatial construction, time–factored changes and cycles of reproduction. The giant cosmic living being showed a form of metabolism, respiration, and reproduction, appearing e.g. as wind currents, water cycle, seasons, tides, lifecycles of plants, animal, and humans, linked to celestial phenomena. People especially considered heaven and earth to act like the human reproductive organs and identified the cosmos with a giant womb. Moreover, the cosmogonic first and essential dichotomy, which causes the world"s diversities, was compared with a kind of primordial sacrifice of a giant cosmic living entity. People regarded the landscape, a cave, a dwelling, a cultic building, or a settlement as an embodiment of the cosmic living entity in miniature, reflecting the characteristics of the macrocosmic being. This study gives an overview of ideas considering the world as a living entity, with respect to cultures through the ages. Concepts of iatromancy are included. The methodology uses approaches of comparative mythology, studies of religions, archaeology, anatomy, medicine, and social anthropology.


Objective To improve the therapeutic effect of TUVP and reduce the risk of complication in treating benign prostatic hyper plastic(BPH). Methods The clinical data of 395 cases of BPH that underwent TUVP were analyzed retrospectively. Results 82.8%(327/395) patients recovered normal urination after withdrawl of indwelling catheter and achieve the expectation complications were observed in 17.2%(68/395) patients.Conclusion The TUVP as the minimally invasive treatment for BPH is feasible with low complication.Highten the view of complication and improve the surgical technic is the key to reduce the complication.


A rational manufacture of solid particles from a liquid medium, wherein the liquid medium is formed as a continuous liquid jet and is cut with a in a cutting plane (8) continuously moving in a direction dividing means into defined portions (9 '), solved by the invention by minimizing by cutting or spray losses due to the division of the liquid jet (9), characterized in that several liquid jets (9) are provided underneath which a common dividing means (5) is arranged, wherein the liquid jets (9) relative (to the direction of movement of the dividing device 5 are arranged) is inclined so that each of the liquid jets (9) with the direction of movement of the dividing means (5) an acute angle (beta) is formed.


Ordination analysis of forest vegetation of national park "Russkyi Sever" (Vologda region) is presented. The main ecological gradients determining the communities` structure are defined. Groups of moss specis, indicating the conditions in the surveyed communities are considered.


Published to commemorate La Mama's 30th anniversary, this collection includes "The Hive" by Sam Sejavka, "It's My Party" by Elizabeth Coleman, "Dark Heart" by Daniel Lillford, "Texas Queensland" by Julie Goodall, "Inconsolable" by Raimondo Cortese, and "No Man's Land" by Ross Meuller.


The aim of this thesis is to on one hand give a good overview of finds found in gotlandic stonefoundationhouses (kampgravar) that were commonly built during the Iron Age and on the other hand investigate the possibility of separating some houses from others and trace social stratification and hierarchies based on the finds. The items of special interest for this goal were those that could be connected to wealth such as drinking objects, Roman objects and objects made of silver and gold. This investigation has shown that on Gotland it actually existed some, often enormous, houses that had a special tendency to hoard exotic valuables. The real standout houses on this subject are the one in Stavgard and the recently excavated building in Hellvi. A secondart goal was to investigate the possibility to date the buildings based on the finds, which was found to be very problematic. (Two years master's thesis in Archaeology)


The asympotic limit of the rate of decay of excitation in the presence of a low concentration of trapping centers is investigated with the assumption that transfer of excitation is governed by an anisotropic diffusion equation. An effective isotropic diffusion constant is introduced which in the appropriate limit leads to results similar to those obtained recently by Richards using variational methods.


In this note we prove among others that
∑1≤i<j≤npipjdS(xi,xj)≤ {2s−1 infx∈X [ Σ k=1n pk (1 − pk) ds (xk, x)], s ≥ 1; infx∈X [ Σ k=1n pk (1 − pk) ds (xk, x)] , 0 < s < 1, where (X, d) is a metric space, xi ∈ X, pi ≥ 0, i ∈ {1, ..., n} with Σ i=1n pi = 1 and s > 0. This generalizes and improves some early upper bounds for the sum Σ1≤i<j≤n pipjd (xi, xj) .


Discussion was made on the optimum design method for MTLD system to control the seismic responses of tall steel structures. The equations of motion of the structure-MTLD system were derived. Based on the dynamic magnification factor (DMF) of the structure-MTLD system, numerical analysis was conducted to study the relations among the parameters for MTLD system, and the optimum parameters for MTLD system were obtained.The design steps for MTLD system and the concrete design method for structure-MTLD system to withstand earthquake were introduced. Eventually, a 30-storey steel structure-MTLD system was analyzed in time domain under seismic excitation


Promulgation of Millennium Development Goals (MDG) in year 2000 gave hope to the world that common interests and challenges such as poverty and hunger, education, gender equality and women empowerment, child mortality and maternal health, diseases such as, HIV/AIDS, malaria, environmental sustainability, as well as global partnerships that were affecting the world could, respectively, be prioritized and responded to within a timeframe of the year 2001 to 2015. In this case, the developing countries like Uganda were accorded great attention. Nutrition has been at the forefront of the MDG implementation as one of the daunting challenges affecting developing countries. This paper is based on a narrative review of quantitative and qualitative data aimed at establishing the progress Uganda made towards achieving the three nutrition related MDG (1, 2 and 4). A timeframe of 2001 when the goals were officially launched up to the deadline of 31 st December 2015 and the adoption of the Post-2015 Development Agenda was considered. The majority of Low and Middle Income Developing Countries (LMIDCS) failed to make substantial progress in achieving most of the goals, including the nutrition related goals. Uganda only achieved MDG one - target 1.A indicator of halving a proportion of people living below less than $ 1.25 a day. To some extent, this helped in alleviating poverty, creating jobs, and generating income and saving and other opportunities which are indeed catalysts to human development and socioeconomic wellbeing. Unfortunately, Uganda missed achieving the rest of the nutrition related MDG. They included: reducing underweight children under five years (MDG 1.8), increasing net enrollment of boys and girls in primary education (MDG 2.1), increasing proportion of pupils starting grade one to last primary grade (MDG 2.2), reducing child mortality rate per 1,000 live births (MDG 4.1) and reducing infant mortality rate per 1,000 live births (MDG 4.2). However, the hope at this particular moment ought to be directed towards tracking and achieving goals in the Post-2015 Development Agenda whose aim is mainly to build on the progress of the MDG. Key words: Nutrition, Millennium Development Goals, Post-Development Agenda, Uganda


Wireless communication technologies have been popularly integrated into biomedical devices. As a result, humans become more and more susceptible to excessive electromagnetic radiation. This paper investigates the electric field and Specific Absorption Rate (SAR) distribution caused by a low profile dipole antenna for three different frequencies. The human head model used is composed of 6 layers that reflect the actual characteristic of human head. The simulation was done using Finite Element Method (FEM) by Ansoft HFSS software. It was found that the distribution patterns for all three frequency bands are similar, only for the magnitude of the fields decreasing as the frequency increases.