The structure of the title compound, [Ni(C 20 H 24 N 6 )(NO 3 )](NO 3 ), consists of a distorted octahedral nickel complex with the central Ni atom coordinated to two N atoms of the benzimidazole moieties, two ethylenediamine N atoms and two O atoms of one of the nitrate ions ; the other nitrate ion lies in a well defined position in the lattice and plays an important role in crystal packing. The dihedral angle between the two benzimidazole rings is 85.1(1)°. The crystal structure is stabilized by a three-dimensional network of N-H...O and C-H...O interactions, and N-H...O intermolecular hydrogen bonds.


Superficial muscular injury without deep perforation frequently occurs during endoscopic submucosal dissection (ESD) of superficial neoplasms. The optimum management of this not uncommon situation is unclear. Clipping could avoid secondary perforation and postresection coagulation syndrome. Here we report a case in which thermal muscular damage occurred during ESD of a squamous cell carcinoma of the upper third of the esophagus due to severe submucosal fibrosis. The damaged area was around 5 × 5mm. Clipping was performed to prevent infectious complications because oral corticosteroid was indicated to prevent stenosis after 75% circumferential resection. However, the clipping caused a deep tear of the muscular layer (▶Video 1, ▶Fig. 1), with visualization of the periesophageal fat secondary to the first clip. The clip was removed using a 10-mm polypectomy snare. A complete 3-mm perforation was confirmed and efficiently closed using an Ovesco clip. In cases of muscle damage without transmural perforation, the risk–benefit ratio of closure with standard clips must be assessed. If closure is performed, aggravation of the lesion should be avoided. Misplaced clips can be removed using a polypectomy snare, enabling treatment of the complication using suitable methods.


PURPOSE OF INVESTIGATION
To define the deletion or over-expression of p53 genes and their prognostic significance in epithelial ovarian cancers.

METHODS
A total of 26 patients with epithelial ovarian cancer, who had undergone second-look laparotomy after primary surgery and six courses of platinum-based chemotherapy were included in the study. Paraffin-embedded archival tissue samples of all cases were examined for deletion and over-expression of p53 gene by FISH and immunohistochemical methods, respectively. The relation between these findings and clinico-pathological prognosticators or survival of the patients were analyzed by the Fisher Exact chi2 test, Cox regression model and life table analysis.

RESULTS
p53 gene deletion, related to single or double allele, was determined in all cases with a range of 6% to 75% of the cancer cells. When 40% was accepted as the cut-off ratio for the deletion rate, seven (26.9%) of the cases were observed to have p53 deletion. Although p53 over-expression was defined in 12 (46.1%) patients, four of whom were also accompanied by p53 deletion, there was no relation between the p53 deletion and over-expression (p>0.05). p53 deletion was also not related to any prognostic factors or survival of the patients (p>0.05). However, cases with p53 over-expression had significantly more advanced stage and higher-grade tumors, and shorter median survival (p>0.05-0.01).

CONCLUSION
p53 gene mutation determined by over-expression of p53 protein has been suggested as an important prognostic factor for epithelial ovarian cancer, however, it has not always been accompanied by p53 deletion.


Ground-basbd aids provide fixes independent of the vehicle's previous history, and often result in relatively low vehicular equipment cost. The present status of the major systems is reviewed. It is concluded that, for the forseeable future, the requirement for ground-based aids will continue. The "lock-and-key" relationship of ground equipment to vehicular equipment makes for slow system changes; thus, while advantage must be taken of every new electronic development, the most pressing need is to apply these developments to existing systems, retaining some compatibility, rather than the development of entirely new systems. This particularly applies to the tactical aircraft field.


In my article on The Sources of Dawlatsháh, which appeared in the January number of the Journal, I have already spoken of the excellent work which I now have the pleasure to present in English dress. For my translation I have used the Tihrán lithographed edition of a.h. 1305, which I have carefully collated throughout with the older of the two British Museum MSS. (Or. 3,507, dated a.h. 1017), and, in all doubtful passages, with the second MS. (Or. 2,955, dated a.h. 1274) also. These MSS. are fully described in Rieu's Persian Supplement, pp. 244–245 and 265, Nos. 390 and 418. It remains only to say a few words concerning the author and the book.


Even though the concept development phase in product development is arguably the most important phase in mechanical and mechatronics design, the available computer- based support for this stage is marginal. This paper presents a new computational model-based method to improve the early phases of mechatronic product design and to facilitate the application from early designs to detailed designs. The paper focuses on model-based Function-Behavior-Structure (FBS) libraries in SysML to support both the manual and computational generation of standard and innovative concepts. In this paper, an approach to re-usable functional models in SysML is presented. The method uses an operator-flow formulation of functions, based on the NIST functional basis, and is validated against a model of an electric car. The generated functional models are validated with respect to the consistency of the flows and tested by associating the functional model directly to the target product component structure. The results of the research are a new modeling approach for function and component libraries in SysML, an associated workflow for modeling of mechatronic systems, and the necessary extensions of the NIST functional basis. The modeling approach provides means for formal functional decomposition followed by an allocation of the functions to structural components that form the target structure.


England's health secretary, Jeremy Hunt, has offered to meet with the BMA's chairman of council, Mark Porter, in a last ditch attempt to avert this week's plan for an all-out strike by junior doctors.

In a letter to Porter sent on Saturday 23 April,1 Hunt said that he would be willing to meet to discuss "a range of issues that can improve the terms and conditions for junior doctors" if the BMA agreed to call off the full withdrawal of labour by junior doctors on Tuesday 26 and Wednesday 27 April.

But Porter said that talks could take place only if the health secretary removed his threat to impose the new contract on junior doctors.

Against this backdrop, the heads of 13 medical royal colleges wrote to the prime minister, David Cameron, on Monday 25 …


The nanocomposites ferrites (BaFe12O19/Ni0.3Cu0.2Zn0.5Al0.5Fe1.5O4) with (x=10,25,50,75,90%) were prepared by sol-gel auto combustion. The micro-structural features of the samples were studied using X-ray diffraction (XRD) and scanning electron microscopy (SEM) techniques. The results were compared which show that the grain size of the nano composites which prepared by sol-gel auto combustion about (25-46) nm.

http://dx.doi.org/10.25130/tjps.24.2019.075


The development of the pore pressure and deformation of a canal slope excavated in unsaturated expansive soil in Zaoyang City during artificial rainfalls is simulated by use of the simplified consolidation theory of unsaturated soil. The computed results are qualitatively agreeable to the observed data.


ABSTRACT BACKGROUND: This study evaluates the radiological parameters of developing subsequent contralateral slips in unilateral slipped capital femoral epiphysis (SCFE) patients at the time of initial presentation. METHODS: The study group included the review of unilateral SCFE patients treated between June 2007 and August 2018. Age, gender, side, stability, posterior slope angle, grade of slip, modified Oxford bone age score (mOBAS), the Risser classification, and the appearance of the triradiate cartilage were evaluated retrospectively. Data were analyzed between two groups: subsequent contralateral SCFE (SCFESC) patients that developed contralateral slip during follow-up and unilateral SCFE (SCFEU) patients that did not develop contralateral slip up to skeletal maturity. Descriptive statistics were used to compare risk factors between groups. RESULTS: This study included 48 patients and 6 patients (12.5%) developed a SCFESC. Only mOBAS was significantly different between groups. The mOBAS scores in SCFESC were 18 in 2 patients (33.3%), 19 in 4 patients (66.7%). The mOBAS scores in SCFEU were 18 in 1 patient (2.4%), 19 in 24 patients (57.1%), and >20 in 17 patients (40.5%). In the SCFESC group, all patients had a Risser score of 0 and all had open triradiate cartilage. CONCLUSION: Patients with unilateral SCFE are at risk for SCFESC, and the mOBAS is the best predictor of risk assessment. We agree that mOBAS score of 16,17 or 18 patients' contralateral hips can be prophylactically pinned. We also suggest pinning or close screening of mOBAS 19 patients that some carry relatively high risk of subsequent contralateral slip.


OBJECTIVE
To compare nonurgent emergency department (ED) visits by insured and uninsured adults in a Midwest community.

DESIGN AND SAMPLE
Records for this secondary data analysis included 84,877 nonurgent visits to a Midwest ED from September 2004 to January 2012. Insured versus uninsured visits were analyzed using t tests for continuous variables and chi-squared tests for categorical variables. Standardized residuals were compared to determine if changes over time were statistically significant.

MEASURES
Variables included demographic characteristics of patients, payment source, patients' access to primary care, acuity rating, time of visit, and the stated reason for the visit.

RESULTS
Of all nonurgent visits, 77.9% were made by insured adults. Insured nonurgent visits were more often made by adults who were female, older, White, and had a primary care provider (PCP). Nonurgent visits on weekdays between the hours of 09:00 and 18:00 were more likely to be uninsured visits. Dental issues were the fourth most common issue for uninsured visits.

CONCLUSIONS
Nonurgent ED visits occur when more appropriate options for prompt care are available in the community. Interventions should target both patients and PCPs. While patients should contact their PCP when in need of prompt care, PCPs should refer patients to facilities other than the ED when medically appropriate.


ABSTRACTThe water content of underground structures can be imaged using surface nuclear magnetic resonance (NMR) in one dimension, two dimensions, or recently, three dimensions. The maximum efficiency can be obtained with a coincident loop configuration in a large-scale area, although the resolution is limited. We have developed a quasi-2D block inversion to characterize a horizontal continuous underground aquifer using a laterally constrained model to improve the resolution of thin aquifers and deep aquifers. Through the simulation of flat surface and irregular surface models, a horizontally layered aquifer with continuously variable water content and T2* can be imaged through quasi-2D block inversion, which is more optimized than the traditional 1D block or 1D or 2D smooth inversion methods. Finally, using a series of profile data obtained from surface NMR field measurements in Mongolia, we determine that quasi-2D block inversion based on a laterally constrained model can significantly improve the disco...


Information retrieval is now fully recognized as an urgent and ever‐growing problem. Our increasing knowledge threatens to become inaccessible and hence unknowable. Two great conferences have alerted the scientific world to the danger and have attempted to particularize the problems. Many workers in different fields have made claims for 'systems' as solutions, others, more cautious, are testing systems, and some are even carrying out work dignified by the name 'research'. All these activities seem painfully haphazard, and little progress has been made; there are no clear lines of advance for the future. Such theoretical approaches as have been made are very elementary and their validity is much disputed. Surveys of current work are now providing a valuable aid to co‐ordination of effort, and yet it seems that most investigators are sticking to their own particular hunches and gimmicks and are ignorant of, or ignoring, the work of others. These are harsh strictures, and need supporting evidence; even then, destructive criticism, by itself, is a disservice to progress, and some constructive effort is needed. I shall therefore attempt first a review of the present position, and then, however inadequately, put forward some suggestions. There is little else that can be done in our present state of groping in the darkness before the dawn.


The Medical Journal of Australia ISSN: 0025729X 7 February 2011 194 3 146-148 ©The Medical Journal of Australia 2011 www.mja.com.au Lessons from Practice sent for urgent mass spectroscopy; and oral administration of vitamins (biotin, B12, riboflavin and carnitine) was comme well as IV bolus doses and then continuing infusions of sod benzoate and arginine. At this time, the working diagnosis organic acidaemia or urea cycle defect with decompensatio by intercurrent illness. Over the following 8 hours, with these measures in place, th transaminitis and hyperammonaemia improved marginally,


Eduction is a complex social system.In the field of after-school education,there exist many problems that should not be overlooked.However,the problems have not been highly valued.This paper argues that the problems should be tackled through concerted actions by school,family and community and in a comprehensive way.


Polymers are emerging as new alternative materials for optical communication devices. We developed two types of polymer‐based devices for optical communications. One type is for ultra high‐speed signal processing that uses nonlinear optical (NLO) polymers in such devices as electro ‐optic (EO) Mach‐Zëhnder (MZ) modulators and EO 2×2 switches. The other is for WDM optical communications that use low‐loss optical polymers in such devices as 1×2, 2×2, 4‐arrayed 2×2 digital optical switches (DOSs) and 16×16 arrayed waveguide grating (AWG) routers. For these devices, we synthesized a polyetherimide‐disperse red 1 (PEI‐DR1) side chain NLO polymer and a low‐loss optical polymer known as fluorinated polyaryleneethers (FPAE). This paper presents the details of our development of these polymeric photonic devices considering all aspects from materials to packaging.


As single-carrier frequency division multiple access (SC-FDMA) is used in long-term evolution (LTE) uplink communications, high peak-to-average power ratio (PAPR) increases power consumption in mob...


In this article there were investigated the social conditions of the rural population of the Republic of Mordovia. It is proved that the village currently is the most depressing social environment. With the use of correlation-regression method evaluated the infl uence of the level of amenities and design of rural areas on the economic effi ciency of agricultural production. The result was the identifi cation of priorities in the funding of social infrastructure of rural areas of the Republic of Mordovia: housing construction, development of retail and consumer services. The proposed method allows to estimate objectively the priorities for funding of social infrastructure and developing a resettlement strategy for rural areas in the region, that eventually contributes to the development of effective motivational climate in the agricultural sector of the economy, raising interest in the results of production and the welfare of rural workers.


Winner of the John Llewellyn Rhys Memorial prize this novel features a young man who enters a pact with the farm manager of his family's estate. The realization that the pact gambles on the death of his two brothers leads to serious bouts of gambling and almost to his destruction.


Pattern recognition is a budding field with many possible approaches. Codebook systems like the k-nearest neighbor classifier, the k-means algorithm, and learning vector quantization all require large numbers of prototype patterns to achieve low error rate recognition. Prototype patterns are an expensive resource for a codebook classifier.
This dissertation seeks to reduce the number of prototype patterns required for low error rate recognition by optimizing the positions of the prototypes in pattern space. The optimization is performed by combining backpropagation learning techniques with heuristic algorithms specifically tailored to cooperate with backpropagation learning. A key feature of the sparse adaptive memory learning architecture is the ability to adaptively change the class labeling of the prototypes. This extra degree of freedom allows these algorithms to be developed for on-line operation where training samples are processed one-at-a-time rather than stored and processed in batches. The quiescent properties of the sparse adaptive memory learning algorithms are found to be consistent with the minimal probability of error decision rule.
This learning algorithm is compared with several others in the context of a synthetic pattern recognition benchmark, handwritten digit recognition, star classification, and inverted pendulum stabilization. Sparse adaptive memory is shown to require fewer prototype patterns to achieve lower error rates. The number of prototypes required for low error rates is linearly related to the recognition problem's geometric complexity.


Cymbopogon winterianus Jowitt oil (CWJ oil) is a vegetable oil with very wide uses in food sector, cosmetics, medicines and chemical industry. Citronelal compound is one of the quality requirements that determine the quality of CWJ oil. This study aims to develop a chemometric-FTIR classification model and to determine the total citronellal content of Cymbopogon winterianus Jowitt oil grown in low and medium lands. The sample used was citronella oil from Jember and Banyuwangi regions. The cleaned CWJ herbal samples were withered, chopped and distilled to produce CWJ oil. CWJ oil was scanned using FTIR spectroscopy and then the FTIR spectras were analyzed using LDA, SVM and SIMCA to form a CWJ oil classification model. The selected classification model was then validated using leave one out cross validation and external validation. The LDA classification model showed the best results with 100% accuracy of model recognition and validation. The results of the determination of total citronellal levels of CWJ oil using the hydroxylamine method showed that samples of CWJ oil from Banyuwangi had higher levels of total citronellal than samples from Jember. The average levels of total citronellal CWJ oil from Banyuwangi and Jember regions were 32.84%, and 26.06%, respectively.


Thank you for reading advances in physiological fluid dynamics. As you may know, people have look numerous times for their favorite readings like this advances in physiological fluid dynamics, but end up in malicious downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they are facing with some malicious virus inside their computer. advances in physiological fluid dynamics is available in our book collection an online access to it is set as public so you can get it instantly. Our book servers spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Merely said, the advances in physiological fluid dynamics is universally compatible with any devices to read.


Usability evaluation is a new work in the field of cartography.In this paper,the concept and the main contents of usability evaluation of electronic map are introduced.Then the methods like usability testing,heuristic evaluation,cognitive browse and task analysis are described.With that,their virtues and shortcomings are discussed.At last,usability evaluation is tested to be an effective way to improve the quality of electronic map usability,and is the core of map design.


Flow chemistry has unlocked a world of possibilities for the synthetic community, but the idea that it is a mysterious "black box" needs to go. In this review, we show that several of the benefits of microreactor technology can be exploited to push the boundaries in organic synthesis and to unleash unique reactivity and selectivity. By "lifting the veil" on some of the governing principles behind the observed trends, we hope that this review will serve as a useful field guide for those interested in diving into flow chemistry.


Long ago, François Gouin chronicled his journey abroad to Germany and his attempt to learn a new language by memorizing an entire dictionary. He self-imposed a "quarantine and prohibited every walk and every dialogue which was not an absolute necessity" (1892, p. 29). Coming out of his isolation, he felt ready to interact with the folks in his new environment and learn at a university. Alas, he found that he could not form intelligible sentences and so was unable to interact with locals or understand the lectures he had deprived himself of all month long. With each failed attempt, he returned to his room to memorize more reference tools. At one time he became temporarily blind yet, he returned to his process. Finally, he gave up. Returning home after an absence of nearly a year, he found that his nephew of three years was now speaking with a very well-developed vocabulary. Intrigued by the magical process of language acquisition, he set out to observe his nephew's language skills. He noticed how his nephew learned by engaging in multimodal activities, pausing to ask questions, and revoicing what the adults had explained. His nephew's world of interacting with new content knowledge and language was a stark contrast to his dependency on memorization. Gouin realized the importance of observing, practicing, and learning language in a meaningful context. Similarly, Emergent Bilinguals are poised to acquire both content and language when the classroom is set up to build on the foundation learners already bring to the classroom and provides socioculturally rich, context-embedded opportunities to continue to develop their native language skills and to acquire new content. Surely, Gouin had a wealth of knowledge that he could have used to make connections in his new environment. Today, bilingual education classes provide children with opportunities to experience language across the content areas like mathematics, science, social studies, music, and art to name a few. Learning is dynamic, a stark contrast to learning in isolation and through memorization.


At beginning of new century, journal "Surveying and Mapping of Geology and Mineral Resources"will meet new situation and duty to run a journal. How to meet situation requirement and how to heighten the quality to run the journal must be reflected on to service surveying and mapping undertaking of geology and mineral resources. Based on summary of experiences to run the journal for 17 years, the new planning to run the journal is put forward through analyzing the situation and duty to run the journal.


We study the inverse Robin problem for the Schrödinger equation in a half-space. The potential differing from a constant is assumed to be compactly supported. We first solve the direct problem for dimensions two and three. We then show that the Robin-to-Robin map uniquely determines the potential .


Abstract : This report is a study of the low detonation speed in nitroglycerine with high speed photography. Low speed conditions were carried out in cylindrical charges of nitroglycerine with the help of an intermediate charge of sodatol through a thin plexiglas plate. The detonation front is disturbed in materials where the speed of sound is less than 2.0 km/sec. The detonation front is stable in materials where the speed of sound is greater than 2.0 km/sec. The mechanism of propagation in the stable wave was found to be a concave wave profile relative to the direction of propagation.


These volumes, part of the Cambridge Monographs and Texts in Applied Psycholinguistics, present contemporary, high-level reviews of research, theory, and practice in reading, writing, and language-learning and in disorders of first language development. Each review focuses wherever possible on the work of its author or authors. This series will help those involved in psychology, linguistics, education, and speech sciences keep abreast of major developments in the many sub-areas of applied psycholinguistics. Volumes 1 and 2 are bound together in cloth, but for greater accessibility are published separately in paper.


Here we presents Modified Gate Diffusion Input technique used to implement radix 8 Booth Multiplier. Use of Booth algo- rithm as compare to other multiplication algorithms in multiplication process shows less computation and less complexity as it mini- mizes the total number of partial products to half of it. Booth multiplier at gate level can be design using any technique such as CMOS, PTL and TG but design with new MGDI technique gives better result in terms of area, switching delay and power dissipation. The radix 8 Booth Multiplier is designed with MGDI technique and layout generated in microwind tool. The simulation done using 0.25um technology at 5v supply voltage and results is compared with conventional CMOS technique. Simulation result shown in tanner tool which shows great improvement in terms of area, switching delay and power dissipation.


ISSUE ADDRESSED
Participation in gambling by young people aged 13-18 years.

METHOD
During 2001, prior to the passing of legislation to minimise gambling harm, more than 500 students from six high schools completed a survey of their participation in gambling during the previous 12 months, and completed three problem gambling screens.

RESULTS
Gambling, including under-age gambling, was a common event. Up to one in five were identified as at risk for problem gambling on at least one screen. Students who were non-European, or were from low socioeconomic areas, were more likely to be at risk for problem gambling. Help for gambling problems was preferred from friends and family rather than others, while inclusion of information in the education curriculum about risk of gambling problems was supported.

CONCLUSIONS
The survey provided evidence for pre-legislation baseline gambling behaviour, and risk for problem gambling, of students attending high schools in Auckland. Levels of risk for problem gambling paralleled the elevated risk found for youth in many countries. Raising awareness, through a school curriculum, of risk for gambling problems among adolescents may be explored as a strategy to reduce the high levels of risk for gambling problems identified.


Drawing on months of ethnographic fieldwork, this paper explores the rising salience of girls' madrasas in India and the feminisation of madrasa enrolments. It argues that rather than the rhetoric of religious conservatism that is conventionally applied to the choice of madrasa education, a range of intersecting factors shape the educational choices of Muslim parents. Employing narratives from the field, it illustrates how the increasing demand for girls' education emanating from within Muslim communities interacts with larger structural factors, socio-cultural concerns, economic considerations, gender norms and anxieties, leading parents to opt for madrasa education for their daughters.


Physiological and psychological instruments were used in the measurement of stress in an occupational training situation. The physiological instrument, the measurement of capilliary blood glucose levels, showed a progressive increase throughout the period of the exercise being observed. The psychological instrument, a stress and arousal adjective checklist (SACL), showed no significant changes in arousal but did show a significant drop in the level of reported stress across the task period. Correlational analysis permits the construction of a model which describes the relationship between the measures and also the results obtained. Changes in the training course are suggested which may alleviate some of the stressfulness perceived by the trainees.


: The convergence of developing real-time interactive program services, the cumulative coverage of wireless networks and the ever-growing admiration of mobile devices, are important in an era of user-centric multimedia wireless services. In this state, heterogeneous infrastructures will co-exist and make certain that the end-user is continuously best associated. The arduous networking loads of wireless multimedia classifications, farther than quality-oriented regulator approaches, are essential to guarantee the best user knowledge terminated time. This paper benevolences some of the current developments in multimedia networking directing principally in areas that have been receiving consideration recently and are predictable to continue to make supplementary interests in the coming years. These areas consist of Quality of Experience (QoE) and a number of related calibration issues, Content Distribution Networks (CDNs), multimedia infrastructures. Simulation consequences illustration the impact and benefit of the proposed result in multi access and multi-operator wireless circumstances by using independent and individual QoE metrics.


Evaluations to quantify the precise targeting of template features and to select template sizes for retinal motion extraction were carried out using cross-correlation with a high speed line scanning ophthalmoscope (LSO) capable of 160 frames per second. The optimal template targeting was located on a retinal vessel pattern with vessel bifurcation or vessel features occupying approximately eighty percent of the template area preferred. The optimal template size for this LSO system was 80 × 80 pixels and it was able to extract retinal motion up to 300 deg s−1 at a speed of 30 Hz. Although the optimized template size was a compromise between having enough image data on the retinal features to make matches reliably and have good temporal resolution, the optimal targeting of the template location and size described here was appropriate and effective in extracting retinal motion. In addition, the determination of cross-correlation templates could be applied to other images having similar properties; i.e., relatively small features of distinct gray levels on an otherwise fairly uniform background.


With the growing use of X rays and gamma rays in the inspection of industrial products, it becomes increasingly important to acquaint both engineers and workers with the dangers to personnel engendered by the rays and with methods of protection from these dangers. Because of the "delayed-action" characteristics which render the radiations one of the most insidious of industrial hazards, safety measures must include not only preliminary protective barrier and distance factors, but must provide for periodic exposure tests and routine measurements of the dose of radiation to which a given worker is subjected.


In this special issue, Ang Bayan puts forward some critical questions surrounding the Party's analysis of the semicolonial and semifeudal social system in the Philippines. We hope that this interview will help our members in further sharpening their grasp of the issues and help in study and research efforts to deepen our understanding of the mode of production. We invite our readers to send their feedback. Additional questions, as well as information, can also be submitted as these may help in future interviews and articles. ] Special Issue Engl ish Edition August 31, 2020 www.cpp.ph


We construct non‐trivial elements of order 2 in the homotopy groups π8j+1+∗ Diff (D6,∂) for ∗≡1,2(mod8) , which are detected through the chain π8j+1+∗ Diff (D6,∂)→π0 Diff (D8j+∗+7,∂)→KO∗=Z/2of the 'assembling homomorphism' (giving rise to the Gromoll filtration) and the alpha‐invariant. These elements are constructed by means of Morlet's homotopy equivalence Diff (D6,∂)≃Ω7(PL6/O6) and Toda brackets in PL6/O6 . We also construct non‐trivial elements of order 2 in π∗PLm for every m⩾6 and ∗≡1,2(mod8) which are detected by the alpha‐invariant. As consequences, we (a) obtain non‐trivial elements of order 2 in π∗ Diff (Dm,∂) for m⩾6 such that ∗+m≡0,1(mod8) ; (b) these elements remain non‐trivial in π∗ Diff (M) where M is a closed spin manifold of the same dimension m and ∗>0 ; (c) they act non‐trivially on the corresponding homotopy group of the space of metrics of positive scalar curvature of such an M; in particular these homotopy groups are all non‐trivial. The same applies to all other diffeomorphism invariant metrics of positive curvature, like the space of metrics of positive sectional curvature, or the space of metrics of positive Ricci curvature, provided they are non‐empty. Further consequences are: (d) any closed spin manifold of dimension m⩾6 admits a metric with harmonic spinors; (e) there is no analogue of the odd‐primary splitting of (PL/O)(p) for the prime 2; (f) for any bP8j+4 ‐sphere (j⩾1) of order which divides 4, the corresponding element in π0 Diff (D8j+2,∂) lifts to π8j−4 Diff (D6,∂) , that is, lies correspondingly deep down in the Gromoll filtration.


In salt and potash mines, the time-dependent deformation mechanism should be clearly understood based on in situ measurements to predict the performance of a mining design. In this study, in situ deformation measurements from the Waste Isolation Pilot Plant (WIPP) and other salt and potash mines were used to determine the transition time from the primary to the secondary creep stage and to investigate the influence of adjacent excavations such as a nearby tunnel excavation, panel excavation and/or pillar extraction on rock deformation.


The invention discloses an inorganic gel-steel composite tube forming technique. The inorganic gel-steel composite tube forming technique solves the problems of low tensile strength, low bending resistance and low impact resistance of an existing composite tube. The inorganic gel-steel composite tube forming technique includes that preparing an inner metal tube and an outer metal tube, compounding the inner tube and the outer tube and filling inorganic gel composite material. The inorganic gel-steel composite tube has beneficial effects of convenience in mounting, light weight, strong bending resistance, pressure resistance, impact resistance and deformation resistance and excellent flame resistance and static resistance, and the inorganic gel-steel composite tube can be broadly used for exploiting and conveying coal, petroleum and natural gas and the like.


Each month, the Bureau of Labor Statistics analyzes and publishes two independently derived estimates of employment . One is based on data from the Current Population Survey (or household survey), and the other from the Current Employment Statistics program (payroll or establishment survey). Data from the household survey are obtained from a sample of about 59,500 households . They measure the work status of individuals and yield estimates of total employment for the Nation . The data from the establishment survey are derived from the payroll records of over 250,000 establishments and are essentially a count of occupied payroll jobs in the nonfarm sector of the economy . Both series are important in appraising labor market trends and in assessing the overall performance of the economy. However, they are not always in agreement in gauging the trends in employment growth . For example, over the 4-year period between November 1982, when the current economic expansion began, and November 1986, the count of total civilian employment obtained through the household survey showed an increase of 11 .3 million. t Over the same period, the estimates of payroll employment derived from the establishment survey rose by a significantly greater amount-12.4 million. If the household employment data are adjusted for the readily measurable differences between the two series-such as the inclusion in the household survey, but not the establishment survey, of agricultural, selfemployed, and private household workers-the growth in employment for that series during the expansion is reduced even further, to 10 .7 million . 2 (See table 1 .) This suggests a discrepancy of about 1 .6 million in employment growth as measured by the two series . Thus, while both series have registered substantial employment gains during the recovery, the difference in their growth inevitably raises questions about the accuracy of one or both of the series and creates confusion in determining just how much employment has grown during the recovery . It is, therefore, important to look further for an explanation.


For the last two or three centuries the changes of land levels in the Northern countries have been known and studied, and attempts have been made at interpreting them. This phenomenon was, as far as we know, first mentioned in a Finnish book of homilies as long ago as in I62I, but it was not seriously studied until the early years of the I8th century, mainly by Urban Hjarne and Svedenborg. The former considered that the phenomenon was merely due to the gradual recession of the whole Baltic Sea to the level of the oceans, while Swedenborg, at least at first, apparently apprehended it as a continuous gradual recession of the waters ever since the Flood. Some time later, about I740, Celsius and Linne began to take an interest in the problem of the changing levels, and these two may be regarded as the founders of the '{waterdecrement thesis", which assumed that the water level was sinking owing to a reduction of the total quantity of water on earth by evaporation, by the absorption of water by the plants, etc. This tentative interpretation thus presumed equal changes of level everywhere. This theory was soon subjected to violent criticisms, naturally invited by its really weak point, viz. the thesis of equal changes everywhere, which at a very early stage was proved to be incompatible with historically established facts. The next attempt to solve the puzzle was made about I765 by E. O. Runeberg, Director of Land Surveys, who sought the explanation in an uplift of the earth's crust due to some disturbance or other of its equilibrium. This idea was developed during the end of the I8th and the beginning of the Igth centuries by a number of prominent scientists, both in Sweden and abroad, e.g. Playfair, v. Buch, Lyell, and Berzelius, and gave rise to the theory of the 'srising walls of Sweden", supposed to be due to the progressive cooling and shrinkage of the earth's crust. The water-decrement theory still had adherents} however, who stuck to their opinions right up to the end of the Igth century. Much earlier-already in the I840wS some Swiss geolopsts had got on the track of the Quaternary Glaciations, and this gave fresh impulses to the solution of this particular problem. The resultant theory of Ice Ages, in conjunction with the modern isostatic


We prove stochastic stability of chaotic maps for a general class of Markov random perturbations (including singular ones) satisfying some kind of mixing conditions. One of the consequences of this statement is the proof of Ulam's conjecture about the approximation of the dynamics of a chaotic system by a finite state Markov chain. Conditions under which the localization phenomenon (i.e. stabilization of singular invariant measures) takes place are also considered. Our main tools are the so called bounded variation approach combined with the ergodic theorem of Ionescu-Tulcea and Marinescu, and a random walk argument that we apply to prove the absence of "traps" under the action of random perturbations.


Museums in an age of paradox museums don't matter? back to basics? stones can speak and objects sing "sex and drugs and rock 'n' roll"...and museums? it's coming home, it's coming home, this football's coming home real things, real places, real people.


As a fundamental vision task, facial expression recognition has made substantial progress recently. However, the recognition performance often degrades largely in real-world scenarios due to the lack of robust facial features. In this paper, we propose a simple but effective facial feature learning method that takes the advantage of facial chirality to discover the discriminative features for facial expression recognition. Most previous studies implicitly assume that human faces are symmetric. However, our work reveals that the facial asymmetric effect can be a crucial clue. Given a face image and its reflection without additional labels, we decouple the reflection-invariant facial features from the input image pair and then demonstrate that the new features with a standard and lightweight learning model (e.g. ResNet-18) are sufficiently robust to outperform the state-of-the-art methods (e.g. SCN in CVPR 2020 and ESRs in AAAI 2020). Our experiments also show the potential of the new features for other facial vision tasks such as expression image retrieval.


Inferior glenohumeral dislocation is a rare entity and among them, bilateral involvement is the rarest presentation. Direct force vector on the abducted arm is the mechanism of injury and is associated with soft-tissue, bony, and neurovascular injuries. An 83-year-old female with a history of unwitnessed falls, diagnosed with bilateral inferior shoulder dislocation clinically and radiologically. She underwent closed reduction, followed by immobilization of bilateral shoulder. There were no associated injuries bilaterally on further evaluation. Bilateral inferior shoulder dislocation is a case to be reported not only because of its rarity but also to address the gray area of management, and more research on the same is warranted for optimum clinical outcome.


A dry ashing method is described for the determination of lead in whole blood. Within the range of 16-200 μg. lead per 100 ml. blood recoveries were 82 to 100%. The method agreed with a standard wet method and is more convenient. Possible sources of error and the uses of the ashing aid are discussed.


TanSat was successfully launched on December 22, 2016, and has been acquiring global measurements of CO2 and O2 spectral bands in reflected sunlight since early February 2017. The atmospheric carbon dioxide grating spectrometer (ACGS) is a spaceborne three-band grating hyperspectral spectrometer suite onboard TanSat. The ACGS is designed to measure high-spectral-resolution, coboresighted spectra of reflected sunlight within the molecular oxygen (O2) A-band range from 0.758 to 0.778 <inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> and the weak and strong absorption bands of carbon dioxide (WCO2 and SCO2) ranging from 1.594 to 1.624 <inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula> and from 2.042 to 2.082 <inline-formula> <tex-math notation="LaTeX">$\mu \text{m}$ </tex-math></inline-formula>, respectively. The spectral resolving power (<inline-formula> <tex-math notation="LaTeX">$\lambda /\Delta \lambda $ </tex-math></inline-formula>) of the ACGS is ~19 000, ~12 800 and ~12 250 in the O2 A-band, WCO2 band and SCO2 band, respectively. The inflight radiometric calibration accuracy is better than 5%, which satisfies the required specification. The wavelength calibration accuracy of the O2 A-band is ~0.19 pm, that of the WCO2 band is ~0.27 pm, and that of the SCO2 band is ~4.75 pm, all of which meet the 0.05 full-width at half-maximum (FWHM) requirement. The spectroscopic performance of the ACGS exceeds the mission requirements by a margin. The ACGS has noise levels that are comparable to or smaller than those observed during prelaunch testing, and the noise has remained stable in the three bands during inflight operations. The signal-to-noise ratio (SNR) levels of the three bands meet the specified requirements. As expected, the ACGS radiometric performance in the O2 A, WCO2, and SCO2 bands was fairly good during its first 17 months inflight.


Reclamation of prime farmland (RPF) after surface mining for coal and farmland protection policy act (FPPA) have a similar function, but the approach to achieve the same purpose is different. The similarity of RPF and FPPA is to reduce the loss of prime farmland and other important farmlands. The reclamation of prime farmland after surface mining for coal allows the disturbance of prime farmland, which is only one of the four categories of important farmland. After disturbance, prime farmland is reclaimed to its original productivity. FPPA's purpose is to limit the acreage of prime farmland as well as unique farmland, and farmland of statewide and local importance from being converted from agricultural uses to non-agricultural uses. FPPA uses easements, mitigation, and federal programs to maintain the farmland base. The soil properties of important farmlands are similar for RPF and FPPA. This paper discusses the soil and programmatic relationship of RPF and FPPA. Additional


At present moment in the typical strength calculations the analysis of the stress-strain state on the basis of equivalent stress and the theories of durability is used for diagnostics of parts. However a number of the basic aviation parts are working at cyclically repeated loadings are exposed to loadings and deformation in the field of a low and high cycle fatigue. In this case there is a need of the calculations of deformation conditions or the stress-strain type which significantly influence on the cyclic durability of parts. In the bound of this research was shown the necessity to use the parameter of the stress state stiffness, which was determined by the G. A. Smirnov-Alyaev criterion for strength calculating of the most loaded parts. The method for estimating of the level of tension of parts and diagnostic of the most critical zones of parts, based on dimensionless energy and complex criteria, is proposed. The effectiveness of the method, which can be used not only to diagnose critical zones, but also to optimize the geometric parameters of the design of critical parts, is shown.


Computation of 2D Helmholtz and transient convection diffusion problems with linear reaction and variable velocity components are implemented with the Green element method (GEM). GEM's fundamental solution which is derived from the diffusion differential operator simplifies the numerical procedure considerably, and together with the Green's second identity, an element to element treatment of the inhomogeneous terms is guaranteed. The reported numerical experiments reveal that the method can be relied on to yield faithful results. © 2004 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2005


Abstract The aim of the study is to identify, and present the CSR practices that have been, and are also currently being implemented by football clubs in the era of the Covid-19 pandemic. Moreover, it also strives to assess the impact of these practices on media coverage. The results of the research show that among the posts published by Zagłębie Sosnowiec on social media platforms, such as their official Facebook profile, and the posts about the results of the matches, tend to achieve the greatest reach. However, on the contrary, posts presenting the ongoing CSR initiatives for the local community come tend to take a backseat, and are considered to be secondary. Furthermore, when it comes to other posts that are related to sports activities or personalities (footballers' birthdays, match previews and information about sponsors), their reach does not tend to differ. From an empirical point of view, this study proves that CSR activities are an imperative element of building relationships with the club's stakeholders.


Approximate multipliers have gradually become a focus of research due to the emergence of fault-tolerant applications. This paper deals with the approximation methods for an approximation multiplier with truncation, probability transformation and a majority gate-based compressor chain. With the help of probability analysis, the proposed approximation methods are utilized in an approximate [Formula: see text] unsigned multiplier to achieve low accuracy loss, high efficiency for time and power. Compared with the precise and approximate multipliers, the proposed design brings 55.0%, 39.0% reduction in delay and 73.8%, 22.6% power saving. The proposed multiplier achieves better peak signal-to-noise ratio (PSNR) values when evaluated with an image processing application.


Multicell cooperation may play an important role in achieving high performance in cellular systems. Multicell cooperation with a single receive antenna at the mobile station has been widely investigated. Applying cooperation with multiple receive antennas, allowed in several emerging wireless standards, has met with some challenges. This is primarily because the transmit precoding/beamforming vector and receive processing have to be jointly optimized in multiple cells to combat out-of-cell interference. In this article, we first discuss the role of the receive antennas in a multicell environment, and then review recently proposed multicell cooperative algorithms and receive antenna techniques for different interference statistics. Finally, we highlight recent work on the fundamental limits of cooperation and the possibility of overcoming such limits by using multiple receive antennas in multicell cooperative networks.


Summary We investigated the structural and functional significance of calcium binding in the factor IXa heavy chain by introducing point mutations into the probable calcium binding site (residues 235 and 245). According to factor IXa computer modelling based on trypsin x-ray structure, side chains of two glutamic acid residues, 235 and 245, together with backbone carbonyl groups of residues 237 and 240, bind a calcium ion. Factor IX clotting activity decreased approximately 25 percent on substitution of glutamic acid 235 with lysine. Activity decreased more than 90 percent on substitution of glutamic acid 245 with lysine. Activity also decreased more than 90 percent on substitution of both glutamic acids by lysines. Factor XIa cleavage of factor IXGlu235Lys and factor IXGlu245Lys appeared normal by polyacrylamide gel analysis. (Factor IXGlu235Lys: Factor IX with Lysine substituted for Glutamic acid at residue 235. Factor IXGlu245Lys: Factor IX with Lysine substituted for Glutamic acid at residue 245. Factor IXGlu235&245Lys: Factor IX with Lysine substituted for Glutamic acid at residues 235 and 245.) Activated factor IXGlu235Lys bound the fluorescent active site probe, p-aminobenzamidine, normally, while factor XIa cleaved factor IXGlu245Lys and factor IXGlu235&245Lys failed to bind p-aminobenzamidine. Plasma purified factor IX titrated with terbium showed an increase in luminescence; however, factor IXGlu235Lys and factor IXGlu245Lys had no effect on terbium luminescence. Radioimmunoassays indicate that in calcium's absence, factor IXGlu235Lys adopts a conformation similar to normal factor IX in the presence of calcium. By contrast, factor IXGlu245LyS's conformation in the presence of calcium is similar to that of plasma purified factor IX in the absence of calcium. We conclude that glutamic acids 235 and 245 are, as predicted, involved in the calcium binding site in the factor IX catalytic domain, and that the correct conformation of this calcium binding loop is essential for maintaining the active site pocket.


The construction of a new CFPP in Indonesia, which was located next to three existing power plants and utilized an existing discharge channel, faced the problem of insufficient capacity of the existing discharge channel to deliver water to four power plants. The problem occurred not only because of the overcapacity of the cooling water flow proposed by the new CFPP but also because of the small size of the culvert located in the discharge channel. This paper discusses several methods to overcome this problem by enlarging the culvert area or by removing the culvert from the channel and replacing it with a bridge. A hydraulic study was investigated using the HEC-RAS software by utilizing inputs obtained from the existing channel geometry and flow measurement data. It was found that additional culverts on both sides with a size of 2 m x 4 m and 3 m x 1 m could reduce the water level by 1.12 m and 0.39 m, respectively. Meanwhile, removing the culvert provided a significant water level reduction of 1.39 m. Enlarging the culvert was chosen as the solution to the discharge channel capacity issue since removing the culvert would require temporarily closing the channel during construction and stopping the operation of the existing power plant.


A modified two-layer Eady model is used to find favorable environments for explosive cyclogenesis by examining baroclinic instability of both short and long waves. The model includes Ekman dissipation and low-level sensible heating, and allows both static stabilities and vertical shears to be different but constant in each layer. It is found that an enhanced low-level shear, a reduced low-level static stability, a relatively large upper-level static stability, and an appropriate height of the interface are favorable for the short-wave development, and that an enhanced upper-level shear and a relatively small upper-level static stability are favorable for the long-wave development, while having opposite effects on the short wave. A small Ekman dissipation is favorable for the development of both waves. Newtonian sensible heating does not directly enhance the development of both waves. A favorable environment for explosive cyclogenesis may not be expressed by a single parameter, but rather by a combination of baroclinic instability with several parameters which contribute collectively to the development of both short and long waves. The relative phase of these waves also plays an important part: the development is enhanced when the surface cyclone is ahead of the upper level wave trough by 1/4π. DOI: 10.1111/j.1600-0870.1987.tb00301.x


This study differentiated it from previous studies by selecting Chinese lifestyle shops in the current situation where lifestyle shops are rapidly emerging due to the increase in single-person households in China and changes in consumption patterns. The purpose of this study is to present basic data for establishing VMD strategies for domestic lifestyle shops wishing to enter China through the analysis of the characteristics of VMD elements. The results of this study are as follows.The research results are as follows. In the display elements of the VMD of Chinese lifestyle shops-GAROSU, CH'IN, and Nome, the appliances and props used differentiated shapes and materials according to the product concept and design. There seemed to be a difference depending on the concept of the lifestyle shop. Also, there were differences in the form of VP and the presentation method of PP and IP in VP, PP, and IP according to the store product group and the amount of products displayed in the presentation element. In a follow-up study, it is considered meaningful to conduct a study on domestic lifestyle shops and a comparative analysis of VMD between Chinese and domestic lifestyle shops.


The 1 MeV electron irradiation-induced degradation of both heteroepitaxial and homoepitaxial p/n InP solar cells grown by MOCVD is presented. The heteroepitaxial cells were grown on Si substrates (InP/Si). The cells were characterized through current-voltage (IV) and deep level transient spectroscopy (DLTS) measurements. After irradiation, essentially the same electron trap spectrum was measured in the two cell types. Several new hole traps were detected, and significant differences between the homo- and hetero-epitaxial cells were observed. The PV response of both cells types was measured as a function of fluence. The homoepitaxial (InP/InP) data was fit to the standard degradation curve, and the results are used to predict the radiation response of the InP/Si cells. The response of a 16% beginning of life (BOL) InP/Si cell is also predicted and shown to out perform GaAs/Ge cells for fluences above 5/spl times/10/sup 14/ cm/sup -2/.


Knowledge has always been important, but recently its functions have been different; the novelty consists in the fact that the speed of generation and transf...


Endometriosis a condition in which tissue resembling endometrium is found in extrauterine sites is of uncertain etiology. Histologic diagnosis depends on the presence of typical endometrial glands and stroma; the foci frequently found at laparotomy or laparoscopy show hemosiderin pigment and fibrous connective tissue. The condition generally occurs in white women aged 20-45 of high socioeconomic status but teen-age cases have also been reported. Clinical symptoms include i nfertility dysmenorrhea pelvic pain associated with menses dyspareunia painful defecation dysuria and hematuria premenstrual spotting and hypermenorrhea. Recommendations for treatment vary and include 1) pregnancy 2) increasing doses of estrogens and progestogens for 6-12 months 3) progestogen alone 4) estrogens alone 5) androgens and 6) danazol an antigonadotropic drug just released by the FDA. Cons ervative surgery might involve presacral neurectomy uterine suspension and excision or electrocautery of all lesions. Radical surgery involving total abdominal hysterectomy and bilateral salpingo-oophorectomy can be recommended only for patients who have completed their family or for those in persistent incapacitating pain.


Drugs that target monoaminergic transmission represent a first-line treatment for major depression. Though a full understanding of the mechanisms that underlie antidepressant efficacy is lacking, evidence supports a role for enhanced excitatory transmission. This can occur through two non-mutually exclusive mechanisms. The first involves increased function of excitatory neurons through relatively direct mechanisms such as enhanced dendritic arborization. Another mechanism involves reduced inhibitory function, which occurs with the rapid antidepressant ketamine. Consistent with this, GABAergic interneuron-mediated cortical inhibition is linked to reduced gamma oscillatory power, a rhythm also diminished in depression. Remission of depressive symptoms correlates with restoration of gamma power. Due to strong excitatory input, reliable GABA release and fast firing, PV neurons represent critical pacemakers for synchronous oscillations. PV neurons also represent the predominant GABAergic population enveloped by perineuronal nets (PNNs), lattice-like structures that localize glutamatergic input. Disruption of PNNs enhances lateral diffusion of glutamate receptors, reduces PV excitability, and enhances gamma activity. Studies suggest that monoamine reuptake inhibitors reduce integrity of the PNN. Mechanisms by which these inhibitors reduce PNN integrity, however, remain largely unexplored. A better understanding of these issues might encourage development of therapeutics that best upregulate PNN modulating proteases. We observe that the serotonin/norepinephrine reuptake inhibitor venlafaxine reduces PNN integrity in murine brain. Moreover, venlafaxine treated mice (30 mg/kg/day) show an increase in carbachol-induced gamma power in hippocampal slices. Studies with mice deficient in matrix metalloproteinase-9 (MMP-9), a protease linked to PNN disruption in other settings, suggest that MMP-9 contributes to venlafaxine-enhanced gamma activity.


Following calls to increase professional communities of practice around research in educational leadership graduate programs, this study describes the ongoing process of creating a research journal club. We share the process of implementation, describe the structure adopted, and the outcomes observed one year after the establishment of a journal club. Through involving graduate students with faculty in bi-monthly conversations about recent research articles, participants engaged in intellectual risk-taking through discussing high quality research. This study highlights the importance of establishing a space to model scholarly research debates, bringing together faculty and students in a community of research practice.


This paper decomposes the time-varying effect of exogenous exchange rate shocks on euro area countries inflation into country-specific (idiosyncratic) and region-wide (common) components. To do so, we propose a flexible empirical framework that is based on dynamic factor models subject to drifting parameters and exogenous information. We show that exogenous shocks to the euro/USD account for over 50% of the nominal euro/USD exchange rate fluctuations in more than 1/3 of the quarters over the past six years – especially in turning points periods. Our main results indicate that headline inflation in euro area countries, and in particular its energy-related component, has significantly become more affected by these exogenous exchange rate shocks since the early 2010s, in particular, for the largest economies of the region. While such increasing sensitivity relies solely on a sustained surge in the degree of comovement for headline inflation, it is also based on a higher region-wide effect of the shocks for the case of energy inflation. Instead, purely exogenous exchange rate shocks do not seem to have a significant effect on the core component of headline inflation, which also displays a lower degree of comovement across euro area countries.


Because of the strong influence of dietary fat on serum cholesterol levels, there has been a great deal of interest in possible parallel effects on bile acid formation and excretion. The output of bile acids in human feces has been determined in several studies by a variety of chemical and isotopic procedures. Values have been reported ranging from less than 0.1 to as high as 2 g per day (1-9). In several of these studies, the inclusion of unsaturated fat in the diet has been found to cause an increase in the total bile acid output, which might account for the concomitant decrease in serum cholesterol level (1-4). On the other hand, in other studies, no such effect of unsaturated fat on the total bile acid output was observed (8, 10-13). Direct analysis of fecal end products is beset with serious technical problems, making it difficult to obtain valid quantitative results (14). The bile acids produced in the liver (cholic acid and chenodeoxycholic acid) are radically modified by bacterial action in the intestine, giving rise to an extremely complex, heterogeneous mixture of products (15, 16). If changes in the diet alter the relative abundance of the several fecal bile acids, then an analysis limited to only one or a few components could give an incomplete and erroneous impression of the changes induced in total bile acid excretion. Lindstedt (17) has previously reported an isotopic method for determination of cholic acid turnover in man based on serial measurements of the


Learning visual based application is one of the most difficult problems for all types of students. This is valid for art and technical education, as well. One of the reasons is that education in computer visualization, especially in the area of 3D modeling, 3D animation, computer-generated special effects and programming for VR applications, is not the same as education for standard computer applications. From technical students it demands more creativity than usual technical subjects, like programming, or math. From art students it asks more technical knowledge and technical ability than they are usually required. The solution lies in changing the learning paradigm towards a flexible and differential approach. Here we discuss the using of computer generated animation and visualization during the learning process.


Paracetamol is the most prescribed drug currently for headaches and fever. Therefore, because of the demand, it is considered an emergent ecosystem contaminant. In this context, this work presents an in-house validation study of a new voltammetric methodology for analysis of paracetamol in natural waters. A boron-doped diamond electrode (BDD) and a Britton-Robinson buffer solution 0.1 mol L-1 as supporting electrolyte were used in the voltammetric determinations. The results were obtaining by cyclic voltammetry (CV) and square-wave voltammetry (SWV). Analytical curves were constructed in the concentration range of 0.25 to 1.51 mg L-1, obtaining values of LOD and LOQ equal to 6.25 μg L-1 and 20.82 μg L-1, respectively. The correlation coefficient (r) found was 0.997, while the determination coefficient (R2) was 99.6 %, indicating, along with the help of statistical tools, a good linearity of the method. Additionally, there were obtaining values of RSD of 3.2 % for repeatability and 12.0 % for intermediary precision, as well as recovery rates in between 80.16 % and 116.45 %. That way, the method can be considered precise, exact and reliable for real samples determinations in


This paper analyzes the connotations and characteristics of development risks of real estate project, introduces the types of development risks of real estate project, and puts forward some countermeasures for dealing with the development risks of real estate project.


What is discussed in this paper is the In-depth Analysis of disambiguating in the combinational ambiguity.First the distribution and characteristics of the combinational ambiguity are summarized.Then the methods existed are concretely analyzed.Finall,all the discussed methods are used for reference to set forth the decision list and adaptive algorithms.


Britain, like a mole in the earth, went through a long process of adapting and adjusting, and finally produced a reasonably humane but quite unradical set of accommodations. It was a sort of slow surge over the years, for anyone in the thick of it, like-the animal images seem unavoidable-being on the back of a cow as it slowly turned over. [Richard Hoggart, in the 1971 Reith Lectures, describing the difference between British and French approaches to the pressure of rising student numbers in higher education. (The Listener, December 2, 1971.)]


3. Any term/concept, if not sufficiently defined (as in mathematics or physics) but focused on the IRRIIS needs should have an explicit working definition which has to enable to use it as an operational concept ( it means some set of operations on it are possible). For example, these definitions should enable in the computational manner : a clear separation of the LCCIs networks layers : physical layer, cyber/information layer and organization/operational/management/humans... layer, and allocation domains of key factors, which are at present: Politics & economics , Politics , Economy , Society , Technology & economy , Technology, (Are these allocations necessary for IRRIIS ?, and for what? we needed an explicit response and consensus).


IMEC has started an EUV lithography research program based on ASMLs EUV full field scanner, the Alpha Demo Tool (ADT). Currently, the ADT is in the final phase of installation. The program focuses on three main projects: EUV resists, EUV reticles and assessment of the ADT performance. The intent of this program is to help improve and establish the necessary mask and resist infrastructure. In this paper, the status and the progress of the program is reviewed. In preparation for a resist process for the ADT, interference lithography has been used to track the progress of resist performance. Steady progress in resist development is seen, especially in terms of resolution, as some materials are now able to resolve 25nm HP. In its initial phase, the reticle project has concentrated on working with the mask and blank suppliers to assure timely availability of reticles for the ADT. An overview is given of the other reticle related activities, as well as first results of a defect printability study by simulation. In the ADT assessment project, simulation studies are reported aimed at the development of optical correction for flare and reticle shadowing effects. The impact of flare and shadowing effects are well understood and strategies for flare mitigation and shadowing effect correction are proposed.


Moral harassment in the workplace is increasingly recognized as a stressor with serious consequences for employees and organizations alike. The work environment can influence people's exposure to moral harassment. Through the comparative study of the Chinese legal regime and the European legal regime, namely, through comparing legal systems vis-a-vis preventing moral harassment at the workplace, t China can learn from the EU by including psychological risks in the occupational hazards, stipulating moral harassment as more comprehensive concept include its complete content in the legal text, and to adopting 'soft laws' in order to complement the statutory laws.


Obturator hernia is a rare abdominal hernia and a presents a diagnostic dilemma. It usally presents with intestinal obstruction in elderly women. Delayed diagnosis and surgical intervention causes high morbidity and mortality due to bowel ischemia and gangrene. Computed tomography is a valuable tool for preoperative diagnosis. This report presents the case of 60 year-old female patient with a small bowel obstruction caused due to an obturator hernia. A computed tomography scan is valuable to establish preoperative diagnosis.


Abstract The Rayleigh-Taylor instability of a compressible plasma in the presence of a horizontal magnetic field is investigated, taking into account the effects of finite Larmor radius. Only transverse perturbations are considered. The problem is shown to be characterized by a variational principle. Using it, the dispersion relation is obtained for a plasma layer of finite thickness and having an exponentially varying density. It is found that the finite Larmor radius effects can thoroughly stabilize unstable configurations. For configurations which are not completely stabilized, the compressibility stabilizes some of the disturbances which are unstable for an incompressible plasma.


We have studied precipitation of noble metals with a view to extending these synthetic processes to other metals. In this paper we discuss the synthesis of gold clusters on the surface of oxide fin ...


Abstract : This project was requested by the Air Force Institute of Environment Safety and Health Risk Analysis to evaluate personal exposure to turbine engine exhaust. Quantifiable indicators of exhaust exposure were identified based on selected components of turboprop exhaust - soot-borne polycyclic aromatic hydrocarbons (PAH), elemental carbon particulate matter and carbon dioxide. Since there were no U.S. occupational exposure limits (OELs) for the first two components, working OELs were chosen by analogy to assess exposure potential. Airborne concentrations of soot-borne PAH were compared with a working OEL of 0.2 mg/cu m(3)and elemental carbon particulate matter with 0.05 mg/cu m(3), both on an 8-hour time weighted average (TWA) basis. No PAH were detected with NIOSH Analytical Method 5506. Breathing zone levels were less than 10 percent of working OELs. Estimated transient elemental carbon particulate concentrations periodically exceeded excursion limits for the working OEL (0.15 mg/cu m(3) for 30-min excursions and 0.25 mg/cu m(3) for 5-minute excursions). The photoelectric aerosol sensor (PAS) is a quantitative instrument known to respond to particle-bound PAH. The PAS is useful for identifying turbine engine exhaust concentration gradients throughout the workplace. Its short averaging time permits correlation of work activities with exposure events and allows documenting process conditions in a near real-time and time history fashion. This instrument needs more developmental work before its response can be stated in terms of an OEL for turbine engine exhaust. TWA elemental carbon concentrations were highly correlated with computed averages of PAS output.


Undergraduate students with a negative attitude towards Math present a unique challenge when teaching computer graphics. Most meaningful concepts in computer graphics involve directly working with Math in the classroom, and implementing tasks in programs requires a reasonable grounding in Math concepts and how to apply them. This paper presents a semester-long experience in using three strategies to address difficulties faced by computer science students who are interested in learning computer graphics, but feel less confident or uninterested in Math. Similar to how Math is taught in schools, we focus on giving students more and more practice in implementing progressively complex visual tasks. Students accomplish some tasks individually to develop a basic understanding before completing other tasks in groups. Students achieve more in a semester than before, and our preliminary observations show a higher rate of completion by students, moderate gains in performance in individual assignments and significant gains in overall class performance.


Examining the direct relevance of the landholding-patriarchy hypothesis to the dynamics of sex discrimination and family-building strategies in rural India, this paper presents evidence that indicates the child sex ratio varies greatly when stratified by size of household landholdings. The results suggest that this hypothesis can be effectively used to study the future implications of the process of demographic masculinisation in the country.


To monitor the environment and determine the source of a pollutant gradient using a multiple robot swarm, we propose a hybrid algorithm that combines two bio-inspired algorithms mimicking chemotaxis and pheromones of bacteria. The algorithm is implemented in virtual robot agents in a simulator to evaluate their feasibility and efficiency in gradient maps with different sizes. Simulation results show that the chemotaxis controller guided robot agents to the locations with higher pollutant concentrations, while the pheromone marked in a virtual field increased the efficiency of the search by reducing the visiting redundancy. The number of steps required to reach the target point did not increase proportionally as the map size increased, but were less than those in the linear whole-map search method. Furthermore, the robot agents could function with simple sensor composition, minimum information about the map, and low calculation capacity.


A previously proposed method of modeling force field transition structures as the lowest energy structure on the seam of two intersecting potential energy surfaces is improved with respect to the force field expression and the efficiency of the optimization algorithm. Comparison with ab initio and experimental results show that the force field method may have the potential of achieving almost quantitative results. It appears that the results from transition state modeling are currently limited by the accuracy of the underlying force field. © 1994 by John Wiley & Sons, Inc.


Zinc antimonate nanoparticles consisting of antimony and zinc oxide were surface modified in a methanol solvent medium using triethoxysilane-based atom transfer radical polymerization (ATRP) initiating group (i.e.,) 6-(2-bromo-2-methyl) propionyloxy hexyl triethoxysilane. Successful grafting of ATRP initiator on the surface of nanoparticles was confirmed by thermogravimetric analysis that shows a significant weight loss at around 250-410 °C. Grafting of ATRP initiator onto the surface was further corroborated using Fourier transform Infrared spectroscopy (FT-IR) and X-ray photoelectron spectroscopy (XPS). The surface-initiated ATRP of methyl methacrylate (MMA) mediated by a copper complex was carried out with the initiator-fixed zinc antimonate nanoparticles in the presence of a sacrificial (free) initiator. The polymerization was preceded in a living manner in all examined cases; producing nanoparticles coated with well defined poly(methyl methacrylate) (PMMA) brushes with molecular weight in the range of 35-48K. Furthermore, PMMA-grafted zinc antimonate nanoparticles were characterized using Thermogravimetric analysis (TGA) that exhibit significant weight loss in the temperature range of 300-410 °C confirming the formation of polymer brushes on the surface with the graft density as high as 0.26-0.27 chains/nm 2 . The improvement in the dispersibility of PMMA-grafted zinc antimonate nanoparticles was verified using ultraviolet-visible spectroscopy and transmission electron microscopy.


Glaucoma is a multifactorial disease where various systemic features are involved in the progression of the disease. Based on initial systemic pro�les in electronic medical records (EMRs), this study aimed to develop a model predicting factors of long-term rapid retinal nerve �ber layer (RNFL) thinning over 5 years in 505 patients with primary open-angle glaucoma. Eyes with faster or slower RNFL thinning were strati�ed using a decision-tree model, and systemic and ophthalmic data were incorporated into the models based on random forest and permutation methods, with the models interpreted by Shapley additive explanation plots (SHAP). According to decision tree, higher lymphocyte ratio (> 34.65%) was the most important systemic variable discriminating faster or slower RNFL thinning. Higher mean corpuscular hemoglobin (> 32.05 pg) and alkaline phosphatase (> 88.0 IU/L) concentrations were distinguishing factors in the eyes with lymphocyte ratios > 34.65% and < 34.65%, respectively. SHAP demonstrated larger baseline RNFL thickness, greater �uctuation of intraocular pressure (IOP), and higher maximum IOP as strongest ophthalmic factors, while higher lymphocyte ratio and higher platelet counts as strongest systemic factors associated with faster RNFL thinning. Machine learning-based modeling identi�ed several systemic factors as well as previously acknowledged ophthalmic risk factors associated with long-term rapid RNFL thinning.


A series of functional diamines, with various side chain structures and length, were designed and synthesised. Four polyimides (PIs) were copolymerised from pyromelitic dianhydride, p-phenylenediamine and four functional diamines. The conformation of the side chains on the surface of PI film was investigated through X-ray photoelectron spectroscopy and attenuated total reflectance Fourier transform infrared dichroic spectroscopy. The results showed that the side chains on the PI film surface aligned outwards in the polymer bulk phase before rubbing. It was found that the length and the contents of the side chains influenced the conformation of the side chains. The interaction between the liquid crystals (LCs) and the side chains on the PI film surface induced the LCs to align vertically.


This paper attempts to explore the identity politics component of two volkisch novels from the 1920s that grapple with the question of the identity of Germans from the old Austrian empire. The two authors, Bruno Brehm and Emil Lucka, were popular prose writers of the interwar period who partook of the general questioning, criticism and rethinking of the 19th century ideologies that occurred after the Great War. Their work — from the vantage point of the history of ideologies — may be interpreted as embedded in the language game of the German conservative revolution, especially in the currents that emphasized the permanent and essential characteristics associated with belonging to an ethnic group and the ethical consequences for individuals of this belonging. For this reason, this paper first briefly introduces post-1918 German volkisch ideology and proceeds to interpret the identity politics of the novels by making use of the key concepts of this strand of "young conservative" [jungkonservativ] thought. T...


Herbal products are complex mixtures of organic chemicals that may come from any raw or processed part of a plant, such as leaves, stem, flowers, roots and seeds. It is estimated that 37% of sales of the world's pharmaceutical products utilized or originated from natural raw material. It appears that dependence upon herbal now are widely acknowledged by the general public and endorsed by the medical profession at large. Current law defined herbs as dietary supplement. In this case, the evidence of efficacy and demonstration of safety not a vital requirement as pharmaceutical drugs. Aligned with increase in worldwide consumption, the safety of herbal medicine is subject of concern. Although herbs are often perceived as "natural", "green" and "back to nature" rhetoric, many side effects have been reported owing to active ingredients, contaminants, adulteration, or interaction with other drugs. The socio-economic changes plus the technological advances, commercial factors, consumers' preferences and changing lifestyles has influenced the way herbal drug are being manufactured and distributed. The various ranges of botanical medicine are now available as over-the-counter (OTC) products. Thus, just like pharmaceutical industry, it has become utmost important to assure quality, safety and efficacy of herbal product through the whole manufacturing process.


This paper investigates the influence of organizational eco-sustainability motivations on the adoption of Green Information Technology (IT) and IT for Green. Drawing from the motivational theory and using data collected from a survey of 176 organizations, the paper develops and tests four hypotheses. The result shows that eco-efficiency and eco-effectiveness motives influence the adoption of (a) technologies that improve the energy efficiency of IT infrastructure and that reduce IT related emissions (b) information systems to reduce travel and travel related emissions and (c) policy and practices that cultivate product stewardship focusing on the IT lifecycle from procurement to end of life. The findings show that while a sense of corporate environmental responsibility predicts Green IT policies and IT for Green technologies, cost cutting and energy conservation are main reasons for undertaking Green IT investments. Pressure from market forces will emerge as relevant motive as early adopters demonstrate favorable outcome out of their green practices.


The invention discloses a navigation information zero tight combination method based on WSN (Wireless Sensors Network)/MINS (Micro Inertial Navigation System), and belongs to the technical field of combination and positioning in the complicated environment. The MINS (Micro Inertial Navigation System) and the WSN (Wireless Sensors Network) are integrated in a local relative coordinate system, the obtained synchronous navigation data is fused in a navigation computer through the UKF (Unscented Kalman Filter), so as to acquire the novel combination navigation method which is higher in precision, wider in navigation coverage and more stable than any other single navigation method.


The stigma associated with the disease may be as subtle as avoidance, or dramatic as physical aggression. COVID-19 has begun to cause social disruption by growing disease-related stigma and xenophobia against some cultural, national, racial or religious groups worldwide.1 People of East Asian origin and those with facial features like them, or those with a travel history to areas affected by the outbreak, are especially being subjected to xenophobia in personal contact and online threats. COVID-19 has arisen as an unknown and newly emerged highly contagious infection that has spread rapidly across the globe and is associated with high mortality, leading to fear of encountering those infected.2 Leaders across the world have taken strict measures such as lockdowns and shutdown of various vital services that have caused chaos in people's lives and increased concerns about the disease.3 Box 1 lists the factors leading to stigmatisation towards those infected with COVID-19.

Box 1
### Causes of stigmatisation towards those affected by COVID-19


In this study, efficiency of humic acids (HAs) derived from various sources to reduce CrVI in aqueous solutions was compared. HAs were extracted from leonardite, peat moss, peat, cocopeat, coal, common char, biochar, vermicompost and sewage sludge. Some chemical and spectral characteristics of the extracted HAs were measured. Then, the reducing efficiency of HAs was measured and its relationship with the determined properties was investigated. To measure the reducing efficiency of HAs, a concentration of 0.1 mM CrVI (as potassium dichromate) in a sodium nitrate solution (0.03M) with a pH of 2 and in the presence of 100 mg of HA per liter was used. The experiment was conducted in three ways (symbolized by E1, E2 and E3). They differ from each other with respect to the method of phosphate buffer addition to release CrVI ions adsorbed by HA. This buffer was added to an aliquot of final extract, to the whole volume of final suspension and to initial solution containing CrVI in experiments E1, E2 and E3, respectively. According to the results, the CrVI reducing efficiency depends not only on the nature of HA but on the method of experiment. The minimum reducing efficiency was observed for common char using experiment E2 and the maximum value was for biochar and cocopeat in all three experiments. The results showed that the two factors of ΔlogK and maximum reducing efficiency in the format of a multiple regression had a significant relationship with CrVI reducing efficiency of HAs.


Parents are increasingly concerned by their teens' use of the Internet. Many teens spend hours surfing the Net when parents would prefer them to be doing homework, out playing sport, or even out at the mall. In particular, concerns revolve around pornography, social isolation and safety. Media reports of cyber-predators have parents fearful that their children could be lured, or even tracked, by paedophiles. Michele Fleming and Debra Rickwood investigate whether parents' fears are well founded or not in this review of the literature on teens' use of the Internet.


For the analysis and design of mechanical and structural systems, it is essential that the analyst or the designer have a thorough understanding of the basic principles of vibration and shock. A physical system is to be replaced by a mathematical model in order to predict its vibration behavior. A study of the vibration characteristics of a single degree of freedom system is extremely important in the study of vibration and shock because the approximate or qualitative response of most systems can be determined by using a single degree of freedom model for the system. Most mechanical and structural systems have distributed mass, elasticity, and damping. These systems are modeled as multi-(n)-degree-of-freedom systems to facilitate analysis of their vibration behavior. A continuous vibratory system will have infinite degrees of freedom. Vibration and shock isolation denotes the storage of energy temporarily and its release in a different time relation.

Keywords:

continuous vibratory system;
multi-(n)-degree-of-freedom systems;
shock isolation;
single degree of freedom system;
vibration


1-Acetyl-3-(4-methoxyphenyl)-5-(1-pyrenyl)-pyrazoline (AMPP) was synthesized and crystallized to yield three types of crystals with different host–guest structures: AMPP crystal (I), AMPP–phenol (II) and AMPP–(2-naphthol) cocrystals (III). Twisted π-conjugated structures and different stacking modes of AMPP molecules were found in the three crystals. In crystal I, pyrene fluorophores adopt a face-to-face π-stacked arrangement, while pyrene fluorophores in crystals II and III adopt the monomer arrangements because AMPPs were widely separated by means of entrapment of guest molecules in the two lattices. Investigation of the optical-properties of the three crystals reveals that they are closely related to the arrangements of the pyrene fluorophores. Face-to-face π–π stacking of the pyrene fluorophores in crystal I cause a broad band emission with a red shift of 40–50 nm relative to pyrene fluorescence in solution. However, the emission spectrum of crystal II is similar to that of crystal III; both of them exhibit two sharp bands with a small red shift of 20 nm relative to pyrene fluorescence in solution, which are induced by the monomer arrangements of pyrene fluorophores and overlaps of π-orbitals between benzene and pyrene fluorophores. These results demonstrate that using a cocrystal strategy to regulate packing modes of pyrene fluorophores is an effective way for exploring highly blue-emissive pyrene derivatives.


Abstract: Cournot oligopoly without product differentiation and with cost externalities is formulated and analyzed from static and dynamic points of view. After characterization of the firms' best responses as functions of their rest of the industry output, a proof is given for the existence of a unique (Nash–) Cournot equilibrium on the basis of an alternative best response functions depending on the industry total output. Finally, the global stability condition for the equilibrium is derived using the firm's gradient output adjustment system.


Foreign portfolio stock investors (FPSIs) often attach political criteria to their investment choices, sometimes in the hope of pressuring policymakers in boycotted markets to adjust their policies. This article asks when the decision to not invest in foreign stock markets for political reasons catalyzes policy change in those countries. Unlike investors in government bonds that target state interests directly, FPSIs directly target the interests of the shareholders and managers of publicly listed firms. I argue that FPSI's policymaking influence is limited by their ability to damage shareholders' and managers' interests and by those shareholders' and managers' ability to affect policy change. I test my theory with a quantitative analysis of a uniquely well-suited data set of policy reactions to CalPERS' Permissible Equity Markets Policy. The results largely conform to my theoretical expectations.


In this article, we provide the first comprehensive study of user-chosen four- and six-digit PINs (n=1705) collected on smartphones with participants being explicitly primed for device unlocking. We find that against a throttled attacker (with 10, 30, or 100 guesses, matching the smartphone unlock setting), using six-digit PINs instead of four-digit PINs provides little to no increase in security and surprisingly may even decrease security. We also study the effects of blocklists, where a set of "easy to guess" PINs is disallowed during selection. Two such blocklists are in use today by iOS, for four digits (274 PINs) as well as six digits (2,910 PINs). We extracted both blocklists and compared them with six other blocklists, three for each PIN length. In each case, we had a small (four-digit: 27 PINs; six-digit: 29 PINs), a large (four-digit: 2,740 PINs; six-digit: 291,000 PINs), and a placebo blocklist that always excluded the first-choice PIN. For four-digit PINs, we find that the relatively small blocklist in use today by iOS offers little to no benefit against a throttled guessing attack. Security gains are only observed when the blocklist is much larger. In the six-digit case, we were able to reach a similar security level with a smaller blocklist. As the user frustration increases with the blocklists size, developers should employ a blocklist that is as small as possible while ensuring the desired security. Based on our analysis, we recommend that for four-digit PINs a blocklist should contain the 1,000 most popular PINs to provide the best balance between usability and security and for six-digit PINs the 2,000 most popular PINs should be blocked.


During the last two decades, increased deformation of road structures due to the increased traffic volume and axle loads, construction errors as well as climatic conditions has been observed in many countries. In order to cope with the deformations that occur on pavements, several types of improvement of the engineering properties of asphalt pavement have been proposed, one of which is the utilization of polymers for bitumen modification. Currently the most used polymer is the elastomer styrene butadiene styrene (SBS) polymer. A laboratory evaluation of the effect of SBS polymer on the properties of the 50/70 penetration grade base (unmodified) bitumen was undertaken. SBS based polymer modified bitumen samples were prepared with different percentages (2-6%) of SBS polymer and their characteristics were determined by means of conventional test methods such as the penetration test, softening point, thin film oven test and storage stability test etc. The morphology and state of dispersion of the SBS polymer bitumen were also investigated using fluorescence microscopy at room temperature. The results gained from the study were evaluated. There was a decrease in penetration and an increase in softening point with increasing polymer content. For the covering abstract see ITRD E133040.


Vines have been grown at Clos Bagatelle since 1623. Replanted and modernised by their parents in the 60's, Luc Simon and sister Christine Deleuze are reaping the benefits of that investment. The slopes of the massif l'Espinouse influence the local climate contributing to rising air currents over the vines with hot dry summers ideal for optimal grape ripening and great wine. This blend of 30% Syrah, 30% Mourvedre, 25% Grenache and 15% Carignan (from 50 year old vines replanted in the 60s) celebrates the next generation in the family – the syrah and mourvedre wines were planted in their birth years. Aged in large oak casks the colour is very deep, with an intense red fruit nose with hints of mint and minerals. The palate is very concentrated, floral, silky and juicy, finishing with hints of balsamic. And to top it all off this wine is a Decanter regional


We report the efficacy of an aqueous extract of Beta vulgaris as a novel, natural photosensitizer for use in photodynamic therapy against Candidiasis disease. This study evaluates the effect of different laser wavelengths (He–Ne: 633 nm, Nd-YAG: 532 nm), power (17, 27 mW) and duration of exposure (5, 10, 15 min) in combination with the Beta vulgaris natural photosensitizer on the viability of Candida albicans causing Candidiasis disease. Although inhibition was observed in all cases, a maximum of 51.91% inhibition takes place with the combination of Beta vulgaris exposed to 532 nm at 27 mW for 15 min by the Agar well diffusion method. The study is important in optimizing different parameters and designing a low-power, compact, non-invasive and portable device for treatment.


Introduction:
 We sought to assess the utility of intravenous thrombolysis (IVT) treatment in acute ischemic stroke (AIS) patients with unclear symptom onset time or outside the 4.5 hour time window, selected by advanced neuroimaging.

 Methods:
 We performed random-effects meta-analyses on the unadjusted and adjusted for potential confounders associations of IVT (alteplase 0.9 mg/kg) with the following outcomes: 3-month favorable functional outcome [FFO, modified Rankin Scale (mRS) scores: 0-1], 3-month functional independence (FI, mRS-scores: 0-2), 3-month mortality, 3-month functional improvement (assessed with ordinal analysis on the mRS-scores), symptomatic intracranial hemorrhage (sICH) and complete recanalization (CR).

 Results:
 We identified 4 eligible RCTs (859 total patients). In unadjusted analyses IVT was associated with higher likelihood of 3-month FFO (OR=1.48, 95%CI:1.12-1.96), FI (OR=1.42, 95%CI:1.07-1.90), sICH (OR=5.28, 95%CI:1.35-20.68) and CR (OR=3.29, 95%CI:1.90-5.69), with no significant difference in the odds of all-cause mortality risk at three months (OR=1.75, 95%CI: 0.93-3.29). In the adjusted analyses IVT was also associated with higher odds of 3-month FFO (OR
 adj
 =1.62, 95%CI:1.20-2.20), functional improvement (OR
 adj
 =1.42, 95%CI: 1.11-1.81) and sICH (OR
 adj
 =6.22, 95%CI: 1.37-28.26). There was no association between IVT and FI (OR
 adj
 =1.61, 95%CI: 0.94-2.75) or all-cause mortality at three months (OR
 adj
 =1.75, 95%CI: 0.93-3.29). No evidence of heterogeneity was evident in any of the analyses (I
 2
 =0).

 Conclusion:
 IVT in AIS patients with unknown symptom onset time or elapsed time from symptom onset more than 4.5 hours, selected with advanced neuroimaging, results in a higher likelihood of complete recanalization and functional improvement at three months despite the increased risk of sICH.


Purpose: Comparing the translucency of various recent ceramic laminate veneers, with different fabricating techniques and luted with two types of adhesive systems. Materials and Methods: Total of 60 discs of 10 mm diameter and 0.7 mm thickness were fabricated, and divided into 4 main groups according to the ceramic materials (Vitablocs Triluxe Forte, VITA Enamic, Ceramill® Zolid and VITA VM®9) 15 specimens for each, that divided into 3 subgroups, with 5 specimens (control and two cement systems groups). All specimens were suspected to Translucency measuring procedures, using a spectrophotometer, to calculate its Translucency Parameter, and Contrast Ratio values before and after adding the cement systems. Result: F-test ANOVA revealed a significant difference in Translucency Parameter (TP) mean value when comparing the four materials in this study. The TP means were arranged in a descending way and showed that; Triluxe (No Adhesive) came in the 1st rank, and recorded the highest TP (3.5225±0.02217), followed by (RelyX Veneer) and the lower mean recorded by (RelyX Ultimate) for the same material where TP (3.44±0.01414). However Ceramill®Zolid (No Adhesive) recorded the 10th rank TP (2.84±0.0001), then (RelyX Veneer) followed by (RelyX Ultimate) came in the last rank as the least TP (2.78±0.00816). Conclusion: It was noticed that, within each ceramic material, the no adhesive application, showed the highest TP, then with RelyX Ultimate adhesive showed the least TP. The first rank of TP appeared in Trilux material.


In the malar bone fracture, conventional radiographic methods has the limitation to analyze the pattern of displacement in an anteroposterior direction of the face. Thirty-four patients with malar bone fractures were examined with the biplane computed tomography (CT), i. e. the axial CT combined with the coronal CT, to analyze the displacement of the fragments.Malar bone fractures were classified into five groups according to the location and direction of the fragments.It is possible to establish a more complete three-dimensional pattern of displacement in malar bone fractures using the biplane CT.