Jan Maya Tamang is a female community health volunteer (FCHV). She lives in ward 8 Terhauta VDC Saptari district one of the more backward and difficult districts in Nepal. This morning Jan Maya is preparing herself for a crusade—a crusade to save the lives of hundreds of children in her village. After a long walk Jan Maya reaches the school where she will administer vitamin A to children in her community. She carries a bag containing a vitamin A register for recording names of children who have received the supplement a flipchart used to facilitate giving nutrition education to children's mothers and caretakers and vitamin A capsules. Her eight years of dedication and hard work in the service of the children and families of her community has raised her status and respect in the eyes of her neighbors. Like Jan Maya there are more than 40000 other FCHVs throughout the country who every six-months administer a round of vitamin A capsule supplements to 3 million children 6 to 60 months of age in 72 of the 75 districts in Nepal. The Vitamin A Program is at present enhancing the immune systems of 94 percent of all Nepali children thereby greatly increasing their chances of survival. Research has shown that periodic doses of vitamin A can lower pre-school child mortality by 30 percent. This figure translates into millions of Nepali child lives which have been saved over the years since the inception of the Nepal National Vitamin A Program (NNVAP) in 1993. Considering the geographic constraints in the country and inaccessibility of health services to most people in Nepal the administration of vitamin A to children by local FCHVs is one of the best possible practices available for saving the lives of children in Nepal. (excerpt)


The artificial neural network represent one of the system of information process which designed by imitating the way of activity of brain of human being in to finishing a problem by doing process learn trough the change of wight sinaps. At this time the standart backpropagation has been developed by 2 learning factors, that are learning rate (α ) and momentum (β). The number of neuron at hidden layer are 50 while learning rate [0,1,...0,5] with error target 0,1. Universitas Sumatera Utara


Psycho-pedagogical group therapy with children of alcoholics was evaluated through semi-structured interviews with the group therapists, covering family history, psychiatric symptoms in the children and their social networks, and the group therapy process. Altogether, 19 children (9 boys, 10 girls) between 5 and 20 years participated. All fathers, except for one step-father, were abusers, as were 50% of the mothers. Almost 75% of the children had been physically abused or witnessed violence in their homes. Fifteen had psychiatric symptoms, most commonly anxiety and depression (75%), whereas 33% were acting out. No child had received child psychiatric treatment for any length of time. Their social networks were small, and conflicts among network members were common. The group therapy sessions could be caracterized in three ways: 1) often the pedagogical work proceeded as planned; 2) sometimes sessions were disrupted, because the children feared to openly discuss the abuse of the parents; and 3) some childr...


Summary We have confirmed our previous findings that rats receiving chronic treatment with active principles of the anterior lobes of the same species fail to become refractory. Under the conditions of the experiment an aqueous extract of acetone-desiccated hypophyses obtained by extraction with dilute sodium bicarbonate produced effects similar to those of implants of fresh anterior lobes.


The anti‐tumor efficacy of single photodynamic therapy (PDT) and radiotherapy (RT) has been greatly affected by inadequate tumor uptake of photo/radiation sensitizers, limited laser penetration depth, and radiation sickness caused by high doses of X‐rays. Here, the authors report a biomimetic coronavirus‐inspired hollow mesoporous gadolinium/bismuth nanocarrier loaded with a new NIR photosensitizer HB (termed as HB@VHMBi‐Gd) for magnetic resonance imaging (MRI)‐guided synergistic photodynamic‐RT. HB@VHMBi‐Gd displayed a faster cellular uptake rate than the conventional spherical HMBi‐Gd loaded with HB (HB@SHMBi‐Gd) because of rough surface‐enhanced adhesion. After intravenous injection, HB@VHMBi‐Gd is efficiently delivered to the tumor and rapidly invades the tumor cells by surface spikes. Interestingly, lysosomal acidity can trigger the degradation of VHMBi‐Gd to produce ultrasmall nanoparticles to amplify the X‐ray attenuation ability and enhance MRI contrast and radiosensitization. Under laser and X‐ray irradiation, HB@VHMBi‐Gd significantly enhances 1O2 generation from HB to induce activation of caspase 9/3 and inhibition of C‐myc, while enhancing hydroxyl radical generation from Bi2O3 to induce intense DNA breakage. By synergistically inducing cell apoptosis by distinct reactive oxygen species (ROS), HB@VHMBi‐Gd exhibits superior anticancer efficacy with ≈90% tumor inhibition. They envision that biomimetic virus‐inspired hollow hybrid metal nanoparticles can provide a promising strategy for imaging‐guided synergistic photodynamic‐RT.


We have developed a new theoretical model based on the MPB4 theory to calculate the differential capacitance of the interface of 0.05mol/L MgSO4 in water and 0.1mol/L TBATPB in nitrobenzene. Our results coincide with the experimental values very well. It indicates that our model may describe well the structure of ITIES not only in the presence of 1:1 electrolyte but also in the presence of 2:2 electrolyte.


A deeper understanding of the biology of the parasite is essential Plasmodium in order to identify targets for interventions, with the ultimate aim of eliminating malaria. Determining the function(s) of essential proteins in has, Plasmodium until recently, been hampered by the lack of efficient conditional systems to abrogate proteins. We report the adaptation of a conditional technology, knocksideways (KS), for use in which can potentially Plasmodium berghei, rapidly inactivate proteins of interest through relocalisation. The system is induced using rapamycin, which allows for KS both  and and is in vitro in vivo effective more rapidly than any other reported system. KS utilises pairs of fluorescent tags that facilitate live imaging and allows for rapid confirmation of efficient protein redistribution on live parasites, allowing for streamlined workflows. We demonstrate the characteristics of the system using transgenically expressed cytoplasmic GFP and provide proof of principle by inducibly redistributing a number of proteins with different native, subcellular locations.  We also demonstrate that KS can be applied to both mammalian and insect stages of . KS expands the range of (conditional) Plasmodium technologies for genetic manipulation of malaria parasites and offers the potential to be further developed for medium throughput phenotype screens. Referee Status:


Our project is to apply optimization methods from machine learning to stochastic control problems, which are traditionally thought to be outside their specialty. A stochastic control problem involves a stochastic dynamical system that can be observed and controlled in limited ways. The control strategy depends on observations from the dynamical system and is to optimize some measure of performance. The optimization methods we apply are variants of stochastic gradient descent that have been developed for machine learning. One advantage of machine learning optimization algorithms is that the control parameters can be adjusted based on only a few stochastic simulations, which are far fewer than what would be needed to get an accurate performance estimate of the system.


Experimental and theoretical investigations of the spectroscopic properties have been carried out on three charge-transfer model systems, covalently linked donor−acceptor compounds of the type pyrene and derivatives of N,N−dimethylaniline (dimethyl(4-pyren-1-ylphenyl)amine (PyDMA), dimethyl(3-methyl-4-pyren-1-ylphenyl)amine (PyMDMA), and (3,5-dimethyl-4-pyren-1-ylphenyl)dimethylamine (PyDMDMA)). Comparing stationary absorption and emission spectra as well as fluorescence lifetimes in different solvents, one can show that small chemical changes such as substitution of ortho-hydrogens by methyl groups on the DMA moiety introduces dramatic effects in spectroscopic and kinetic behavior. On the basis of infrared measurements and quantum chemical calculations, the experiments are interpreted within a statistical framework, with particular emphasis on the discussion of preferred large amplitude motion (twist angle) and pyrene-specific vibronic coupling.


In order to separate small magnetizable particles down to the micro- and nanometer scale, high-gradient magnetic separation is a well-established process. The superposition of magnetic filtration with centrifugation, called magnetic field-enhanced centrifugation, permits continuous separation. The separation efficiency of magnetic filters and the prediction of the efficiency is described. The separation efficiency of one single stage could be enhanced from 51 to 78 % by increasing the wire number and improving the wire cross section. The separation efficiency on different particle sizes at different filter stage numbers and comparison to the prediction of separation efficiency based on magnetic forces and the fluid drag force is demonstrated.


This case-control study evaluates the association between a remote history of venous thrombosis and later risk of venous thrombosis in older adults.


In this study, the anatomical, palynological and karyological properties of Verbascum weidemannium Fisch. & Mey. growing around Sivas in Anatolian part of Turkey were investigated for the first time. As a result of root and stem anatomy studies showed that both organs are in secondary structure. Cambium consists of 2-3 cell layer in root and 2-4 cell layer in stem. Leaves have dendroid hair on both surfaces. According to mesophyll layer leaf is bifacial. Stomata are anomositic and located on both surface. Sepals have dendroid hairs on both surface and have 7-11 cell layered chlorenchyma. Petals are covered single layered papillose cubic and rectangular epidermis cells in upper surface and nonpapillose cells in lower surface. The filament is approximately triangular shaped in crooss-section and vascular bundle is concentric-hadrocentric. Pollen grains of V. wiedemannianum are tricolpate, oblate-spheroidal; P/E ratio is 0.98 and exine ornamentation is reticulate.


In an earlier paper by one of the authors (9) a theoretical analysis suggested that, at certain speeds, large vibrations can occur in a pair of spur gears, without any manufacturing errors and without any external excitation, provided the damping is less than about 0·07 of critical. In this paper a summary is given of an extension to this theoretical analysis, but the main part is concerned with experimental observations on a back-to-back gear test rig. From these observations the maximum dynamic loads on the teeth have been deduced. It has been found that for all applied loads between zero and 1 1/4 times design load, the maximum dynamic load never exceeds twice the design load (the design load is the load which gives a constant transmission error at low speed). It should be noted that if the design load (for which the profile modification is specified) is appreciably greater than the applied load, the dynamic increment may be very large. Excessive profile modification should therefore be avoided. As the...


The blood flow and flow distribution of the small intestine of cat were studied at various levels of vascular smooth muscle tone by means of the Kr85 wash-out technique. At "resting" total intestinal blood flow about 80 per cent of flow was distributed to the mucosa-submucosa, where the flow rate amounted to 40–80 ml/min × 100 g. Blood flow of the muscularis was then 10–20 ml/min × 100 g. As total intestinal blood flow was increased by constant, intra-arterial infusions of isopropylnoradrenaline a larger and larger part of intestinal blood flow was distributed to a highly vascularized part of the intestine probably located in the submucosa and adjacent parts of the mucosa. At intense vasodilatation (venous outflow 225 ml/min × 100 g) about 60 per cent of total flow passed through these intestinal structures, the blood flow of which amounted to 800–1000 ml/min × 100 g. The blood flow of the rest of the mucosa-submucosa increased concomitantly to 150–200 ml/min × 100 g and that of the muscularis to 35–40 ml/min × 100 g.


In [1] a new integer-estimable GLONASS FDMA model was introduced. The new model is generally applicable and guarantees, independent of the actual channel number entries, the integer-estimability of the new GLONASS ambiguities. As the model has a close resemblance with CDMA models, available CDMA software is easily modified and existing methods of integer ambiguity resolution can be directly applied. In this contribution we will show how the integer-estimable FDMA model can be combined with the new GLONASS CDMA signals that are currently under development [2], [3]. We present the combined GLONASS-only FDMA+CDMA model and we analyse its strength for instantaneous integer ambiguity resolution. This will be done formally as well as empirically using real data.


Dissimilatory Fe(Ⅲ)reduction shows important impacts on the geochemistry of anaerobic environments.The community structure of iron-reducing microorganisms in dried paddy soil changed continually after flooding.The objective of this study was to investigate the characteristics of iron reducing microbial community in different flooding period with various carbon sources.Solutions extracted from Zhe-jiang paddy soil in different flooding period were used as inoculums while ferrihydrite synthesized artificially was used as a sole electronic ac-cepter.These solutions including ferrihydrite were cultured under anaerobic condition at 30 ℃.Yield of Fe(Ⅱ)and pH were mensurated termly and analyzed by Logistic model.The results showed that microorganism communities under iron reduction in different flooding periods had rapid response on glucose while they showed a later response on pyruvate,comparing to glucose.When pyruvate was used as a carbon source,accumulation of Fe(Ⅱ)reached to a very high level after 30 days incubation.When lactate was used as a carbon source,both of flooding 20 days treatment and 30 days treatment had significant higher accumulation of Fe(Ⅱ)in 15 days incubation than the other treatments.The maximum Fe(Ⅱ)accumulation of this treatment was 538.47 mg.L-1 and rate of Fe(Ⅲ)reduction was 75.81%.During the incubation,pH of solution decreased from neutral to acidic for glucose,stayed around neutral with slight acidic for pyruvate and lactate,and was slightly alkaline for acetate.Diversity of community structure in different flooding period induced the different potential of iron reduction.Various carbon sources could index the different iron reducing microbial community.Iron reducing microbial community in short flooding pe-riod could use glucose and pyruvate as predominant electronic donors while those in longer flooding period used lactate or acetate very well.


Lactobacillus helveticus has been recognized as an adjunct culture that contributes to flavor development in cheddar cheese. However changes in peptides profiles throughout ripening and their anti‐inflammatory effects on HUVEC have not been investigated.


Summary The East African Rift system is an exceptional feature on planet earth where plate tectonics plays in extension within a continent, with hot mantle up-lift and high heat flows allowing for geothermal resources at shallow depth. Whereas the industrial development of geothermal energy is still embryonic, with a spectacular success in Kenya, particularly at Olkaria (600MWe installed), but developing fast thanks to appropriate tools, there is still a lack of appropriation of geothermal development at local level, as elsewhere in the world, where projects answering local needs with variety of usages prevail over large size units serving the electricity needs. The "geothermal village" concept was described in 2004, and several attempts to promote it could not reach a full success, despite the identification of numerous sites where local resource really fits the demand. The present usage is mainly handled artisanally, with geothermal steam condensation to produce water for agro-pastoralist and human needs. Answering a call from LEAP-RE research program issued by the European Union, devoted to renewable energy in Africa, a team of scientific partners joined their efforts to fill the knowledge and technology gaps that need to be solved in order to succeed in a socially mastered development.


In Roman times a few cities situated on the western coast of the Black Sea constituted a Western Pontic league or koinon. Its official name was probably κοινόν του εύωνύμου Πόντου or simply ευώνυμος Πόντος (ISM II 92, 97).' Until the reign of Septimius Severus six cities (Istros, Tomis, Callatis, Dionysopolis, Odessos, Mesambria) participated in this league. The number of participants indeed gave rise to one of its attested names: Hexapolis. After Mesambria left the koinon, it became a Pentapolis. To the best of our knowledge Istros, Tómis, Callatis, Dionysopolis, Odessos and Alesambria did not participate in the concilium prouinciae Moesiae Inferioris active in the western part of Lower Moesia. Instead the koinon served as their provincial assembly. It is the best documented among the provincial assemblies in the Danubian region.-' Its raison d'être was to worship the emperors but, as with other assemblies, the Western Pontic koinon also served as an intermediary between the member-states and the emperor and governors of Lower Moesia. Most probably its annual meetings provided an opportunity· for public entertainment, perhaps in the form of gladiatorial games. Staging the ///¡mera gladiatoria was practically obligatory for high officials of provincial assemblies in the Roman empire. Indeed, two presidents of the Western Pontic league (pontarchs) at the time of the Severi were praised by the people and council of Tomis for having organized such games. The existence of the Western Pontic league is attested only in the second and the first half of the third centuries A.D. There have been, however, many attempts to date the origin of this koinon in earlier epochs: e.g. Droysen and Kazarov wanted to set the date


According to course feature and teaching objective of marketing and based on the research on marketing specialized curriculum construction, some teaching methods which are different from traditional specialized curriculum theory teaching including heuristic teaching method, item teaching method, case analysis teaching method, and simulation teaching method are brought up. The practice proves that these methods, which are independent and correlated with each other, are very useful for students majored in marketing to promote practice capacity and overall quality.


Whether they can legitimately be described as virtuosi or one man (sic) bands, information professionals working in isolation have become something of a cause celebre recently. This study looks first at their contribution to the collection, analysis, synthesis and dissemination of information in a single field — that of employment studies. Then, using the test of relative job satisfaction as a function of effectiveness, the characteristics, problems and satisfactions of the workers themselves are examined. The present work is based on two reports of a survey undertaken on behalf of the British Library Research and Development Department in 1983.


The research investigates elaborately the literatures on knowledge transfer indexed by science literatures network general database in CNKI during 2001-2011 from such five aspects as publishing time,author characteristics,source journals,contents,and cited numbers to find the development proce dure and primary characteristics of these research on knowledge transfer in China.And on this basis,some suggestions are brought forward to improve the research on knowledge transfer.


Use of stereochemical probes shows that both the formation of permethylscandocene tellurolates (via tellurium insertion into Sc–C bonds) and the decomposition of permethylscandocene tellurolates (via extrusion of TeR2) proceed with retention of configuration in the probe, implying concerted transition states for both reactions.


This data comprises a python module that implements the horsetail matching method presented in this publication, and can thus be used to recreate the results in the paper. This python module is also available at: http://www-edc.eng.cam.ac.uk/aerotools/horsetailmatching/, but is archived here.


In terms of imagery and design, be it decorative or symbolic, Northeastern Native art is rich and diverse. No more so than the art of Haudenosaunee (Iroquois) beadwork which evolved over the course of the nineteenth century into a myriad of forms, from articles made for indigenous use to material produced for the early souvenir market.


The electronic origin of the influence of the anomeric effect (negative hyperconjugative interaction, NHI) on the Fermi contact (FC) term of 1 J(C, H) couplings has been studied from a theoretical point of view at the DFT-B3LYP level. The HN=CH2, molecule was chosen as the primary model compound, in which both FC 1 J(C, H) couplings were decomposed into bond contributions with the natural J coupling dissection approach (NJC). Differences between the 1 J (C, H)FC couplings for C——H bonds in synperiplanar and antiperiplanar orientations with respect to the nitrogen non-bonding electron pair closely follow the experimental trend. They are made up chiefly of three NJC contributions: 'bond', 'direct lone pair' and the 'carbon-core orbitals'. The NHI influence on these terms was studied by applying the natural bond orbital (NBO) deletion procedure to the charge transfer interaction into the antiperiplanar (C——H) antibond (n(N)→(C——H)*) prior to the NJC dissection calculation. The dielectric solvation effect on both the total FC terms and the respective NJC contributions was estimated by carrying out the calculations using the polarization continuum model. Inhibition of the anomeric effect is evident when the solvent polarity is increased. NHI saturates rapidly with increasing solvent dielectric. Specific solute-solvent interaction effects on 1 J(C, H) couplings were estimated by evaluating molecular complex models of the form CH2=HN…S (S = H2O and DMSO).


The utility model relates to a uterus warming ovary care treasure, which comprises a uterus abdominal belt which is fixed with a viscous hasp, a medicinal bag and a covered edge and a physical hot core, wherein the uterus abdominal belt is formed by connecting a left piece, a right piece and a rear piece integrally; the left piece and the rear piece are made of elastic cloth in which through holes are positioned; support strips are also fixed on the rear piece; and the self-heating physical hot core is put into the medicinal bag. According to the uterus warming ovary care treasure, the support strips are distributed in the rear piece uniformly, so that the uterus abdominal belt can be supported smoothly, and the uterus warming ovary care treasure is used softly, comfortably and flatly; the shrinkage of abdominal muscles of parturients can be enhanced, and the replacement of uterus can be accelerated by utilizing a physical effect of the uterus abdominal belt, so that the physiological rehabilitation of the parturients in the puerperal state is promoted effectively; the physical hot core on the uterus abdominal belt is applied to acupuncture points, transdermal absorption magnet therapy and main and collateral channels are combined, and the reduction of waistlines is promoted by using medicines, so that the effects of promoting blood circulation to remove blood stasis, clearing damp, expelling heat, warming uterus, caring vaginae, caring ovary, improving microcirculation, promoting the shrinkage of postpartum abdominal walls and involution of uterus, conditioning a female reproductive system, restoring the original bodily forms of the parturients and protecting the physical and psychological health of the parturients are achieved.


The third age — that portion of the lifespan between retirement and death — is growing progressively longer as more people retire early and people live longer. Someone who retires at 60 may expect to live well into his or her 80s, and with luck during their last 20 to 30 years those with good pensions will have more money and fewer responsibilities than at any earlier time.

As an interested spectator of retirement strategies it seems to me that doctors tend to choose one of two contrasting approaches. Some give up their …


It is possible to filter out the primary ionizing electrons from the ion extraction region of a multicusp source by installing the filament inside the dipole fields of the permanent magnets and thereby enhance the H+ ion species in the extracted beam. An optimum position of the filament has been determined such that a quiescent plasma together with a uniform plasma density profile across the extraction plane can be obtained.


In this paper, we consider preemptive scheduling of a set of fixed-priority, sporadic tasks on multiprocessors from both real-time and fault-tolerant perspectives. We propose a fault-tolerant multiprocessor scheduling algorithm, called FTGS, exploiting time redundancy to tolerate both task errors and processor failures. The main contribution of this paper is the derivation of a feasibility test for our proposed FTGS algorithm. This feasibility test when satisfied guarantees that all the deadlines of the real-time tasks are met even in the presence of task errors and processor failures. The major strength of FTGS algorithm is the fault model it assumes, we consider a variety of software and hardware faults that may lead to task errors or processor failures. The novelty of our proposed feasibility test is that the resilience of resource constrained embedded real-time systems can be determined for different combinations of task errors and processor failures.


In order to study the super-tough and flame-retardant PBT materials, the effects of PTW elastomer,POE-g-GMA elastomer and the composites of MBS / PC on the mechanical and flame retardant properties of PBT as well as the effects of DBDPE and brominated epoxy resin on the mechanical and flame retardant properties and the product color of PBT were investigated. The results indicated that the toughening system of the composites of MBS / PC worked best,and owned the highest retention rate of tensile strength and flexural strength,while the effects on the flame retardant properties of PBT were also the minimal. The results also indicated that the flame retardant system of brominated epoxy resin owned the higher flexural strength and the better retention rate of tensile strength and notched impact strength as well as the higher whiteness of the product,and the flame retardant efficiency of brominated epoxy resin was slightly lower.


Since the administrative measures of accounting check for military hospital were put in force,the preferable effects have been achieved,but its limitations also appeared.In the article the problems were analyzed and suggestions were put forward to adjust it.


Results in $p$-adic transcendence theory are applied to two problems in the Chabauty-Coleman method. The first is a question of McCallum and Poonen regarding repeated roots of Coleman integrals. The second is to give lower bounds on the $p$-adic distance between rational points in terms of the heights of a set of Mordell-Weil generators of the Jacobian. We also explain how, in some cases, a conjecture on the 'Wieferich statistics' of Jacobians of curves implies a bound on the height of rational points of curves of small rank, in terms of the usual invariants of the curve and the height of Mordell-Weil generators of its Jacobian. The proof uses the Chabauty-Coleman method, together with effective methods in transcendence theory. We also discuss generalisations to the Chabauty-Kim method.


A carbonized hard Ti-base alloy with high weldability, anti-wear nature and toughness is prepared proportionally from the hard phase (TiC or the mixture of TiC and WC), adhesive phase chosen from Ni, Co and Fe, Cu and Mn or Mn compound, C, tantalum carbonate and/or niobium carbonate, V or V compound, Cr or Cr compound, and Mo or Mo compound.


Architects acquire an important part of their design knowledge from existing designs. Specific design projects from the past form an indispensable source of information and inspiration. Hence the idea to develop a digital library of design cases that can be easily accessed during design. The paper describes a recently developed prototype of such a case library, intended to assist architecture students in the studio, yet with the potential of expansion into the office setting. When students enrol into a design project, they usually receive a reader with some relevant examples. At first sight, the digital case library only seems to represent these examples into another medium, yet there are some important differences between both. Unlike the reader, the library has at its core an indexing-system which allows the easy retrieval of relevant information. By labelling projects with several features and making links between similar designs, the tool supports both directed search and browsing. A second difference is that the library is interactive. Students are not only able to consult interesting examples, but also to add other projects they consider relevant, to make links between them, to create extra indices etc. Finally, the tool allows to combine several media and to create links to external information sources.


THE purpose of this article is to describe two methods, which may be employed independently of chemical analysis and within their limitations, to classify steels.


Objective: This study was determining the skeletal, dental, and soft tissues changes is respons to camoflage Class III treatment. Methods: A male patient 14 years, 10 months with malocclusion of dental Class I and skelettal Class III, included crowding and crossbite anterior, overbite 3 mm, overjet -1,5 mm, maxillary midline shift to the right 2 mm and mandibular midline shift 1 mm. Treatment was extraction of maxillary and mandibular first premolar with standard edgewise appliance and retention of hawley retainer. After of treatment, correction of the crowding, crossbite anterior and midline, with dental relation class I, normal overbite and overjet is 2 mm. Results: This case is Angle's class I malocclusion where sagittal interarch relationship is normal, it is preferable to extract in both the arches in order to maintain the interarch relationship, so was that extraction of the right first premolar of maxilla and mandibular. Conclusion: Careful management of the extraction space preserved normal lip support and facial profiles


Abstract Fluorescent powders provided an effective method for marking and monitoring flight activities of adults of Glischrochilus quadrisignatus (Say), a pest of processing tomatoes. Observations and experiments were conducted that would have been impossible with unmarked insects. Experiments showed that small numbers of beetles located hampers with damaged tomatoes placed 300 m from a release point within less than 2 h. Tomatoes picked and cracked 1, 2, or 3 days prior to release of marked beetles attracted beetles in a ratio of 1:2:3. Approximately 3.5 times as many starved as fed beetles were attracted to damaged tomatoes. Most of the beetles landed on the ground near the hampers and entered via the floor, rather than landing on tomatoes at the top of the hamper. The significance of the above four findings in relation to control of the insect is (1) beetles are probably attracted to damaged tomatoes from a wide area; (2) tomatoes should be harvested as close as possible to the scheduled time of delivery to the factory; (3) more severe infestations could occur subsequent to periods of inclement weather when beetles, are unable to move to new food sources; and (4) the treatment of hamper floors with insecticides before harvest may assist in control.


DRAWTINGS HAVE become increasingly popular as an aid in clin ical diagnosis. * It has been claimed that they can be used todetectpath ology and to formulate hypotheses about the presence of disturbances in interpersonal relationships and distortions in the self concept. As an adaptation of this technique to individuals in education, Travers and Rab inowitz devised a drawing test in which their subjects were asked to draw a teacher with a class. The hypothesis was that such drawings would reveal the individual's concept of the role of the teacher. It was further hypothesized that distortions in the depiction of the teacher and the students in the class, the amount of tension and emotional disturb ance in the drawings (determined by ratings) would be related to disturb ed behavior in teacher training.


ABSTRACT After the adoption of the U.N. Declaration on the Rights of Indigenous Peoples (UNDRIP) in 2007, the Government of Japan recognised the Ainu as an indigenous people in 2008, and it began developing the Ainu policy. However, the policy focuses on individual rights and cultural promotion, failing to implement UNDRIP. In this situation, private standards, notably forest certification, are increasingly paid attention to because the mechanism requires forest managers to respect the rights of indigenous peoples outlined in UNDRIP. With this in mind, the study will discuss the implications and challenges of forest certification in relation to the Ainu indigenous rights in Hokkaido, particularly the 2012 revision of Principles and Criteria of Forest Stewardship Council. It will take a close look at newly added requirements on UNDRIP, identification of indigenous peoples, and the right to free, prior and informed consent. Through this analysis, the study will clarify that the revised standard could improve the relationship between the Ainu and forest managers. However, by considering the current situation of the Ainu, the study will also point out the necessity of careful audit process, further effort in working on the Governmental policy and the increase in auditors' familiarities with indigenous rights.


A recent note in the Random Samples section ("Payoffs seen from Keys fishing ban" 12 Mar. p. [1631][1]) describing preliminary findings of studies within no-take zones of the Florida Keys National Marine Sanctuary concludes that "[i]t is still too early, however, to measure a hoped-for benefit


"Aesthetic appreciation and creation" is one of the core literacy of Chinese discipline, poetry appreciation is the focus and difficulty of literary appreciation, this paper hopes to explore Liu Yong's Rain Bell, on the basis of feeling and experiencing the language, image and emotional beauty of words, through different times, different connoisseurs of their works, so as to help students in the process of understanding poetry appreciation of the basic steps and methods. And try to explore the multiple realms of word expression.


To reduce pollution, decrease the production of carbon dioxide, and to maintain a secure supply of energy, interest continues to grow in the area of renewable energy especially since there is a finite supply of cheap oil. Wind energy is one of the most viable options to consider and supply part of the energy needed to reduce dependence on foreign oil. However, it is difficult to predict the wind speed in an environment with many obstacles such as buildings and trees and getting accurate dimensions of those obstacles is difficult particularly on sloped mountainous terrain. In this study a drone was used to create a 3-D map of the campus of the Catholic University of Pusan. The dimensions and elevations for the 3-D map were used to make a model of the school campus in the CFD program Envi-met. Simulations were run for five different wind directions and 4 different elevations to find the location that would give the highest electrical output for a wind turbine. When considering all of these variables it was found that the optimal location was above the Student Union which had a 40% higher wind speed and could produce 274% more electrical power than the original wind speed.


In order to avoid safety accidents caused by the incorrect operation,Dongfang 1-1 Gas Field has made the innovation to implement figure culture operation procedure.This paper includes the steps and methods of the operation procedure,and its major content,advantages and effects.The implementation of this procedure has solved the problems of the traditional operation procedure with the pure literal presentation.Since the implementation of figure culture operation procedure in Dongfang 1-1 Gas Field,there has occurred no incident or accident,which proves its good effect of risk control.


Using post-tensioned metal straps (PTMS) as a method of strengthening reinforced concrete building members is relatively new, however, it has been tested mostly on small specimens. Therefore, this study is an attempt to show the effectiveness of PTMS fully wrapped around medium- scale steel reinforced concrete (RC) beams to enhance their shear strength. For this purpose, four normal RC beams are constructed without transverse reinforcement with dimensions of 160 mm × 240 mm x 1050 mm which are width, depth, and length respectively. To strengthen the beams, PTMS is wrapped fully around the beams at different locations with different strip numbers. It is found that if used properly, PTMS can effectively alter the type of failure of the beams from a brittle shear failure to a ductile bending failure. Additionally, the load-carrying capacity of the beam can increase by 143%, 170%, and 182% by using two, four, and six strips of PTMS respectively. Moreover, the deflection capacity increases by 643%, 557%, and 653% by using two, four, and six straps of PTMS. Finally, after using PTMS on the beam there is a reduction in the number of cracks and the location of their appearance will be localized in the center of the beam.


It is very difficult to select the right supplier from supply base for the global supply chain due to many challenges and problems especially for the developing countries such as Pakistan. In the present study primary data is collected via adopted questionnaire from cases of the total 170 cases from Kotri manufacturing companies of Sindh, Pakistan. For the analysis of gathered data many tests were applied such as reliability test, factor analysis and structural equation modelling in SPSS and AMOS software. Findings, revealed the partial mediation for both quality and delivery variables in the presence of mediating variable information flow. However, the quality confirmed the more important variable for the supplier selection in manufacturing companies of Kotri, Sindh, Pakistan due to higher beta value than delivery variable. In the past research scholars explored the direct relationship between quality and delivery for the supplier selection but, in the present mediating variable information flow is introduced in order to verify the strength of studied variables. Lastly, based our limited knowledge this would be the first study conducted on Kotri manufacturing companies of Sindh, Pakistan.


It is a security element for increasing the security against forgery of a security document, in particular an identity card, a passport or an identification card will be described. The security element (1) has a first diffractive region (15) having an open, visible with a naked eye code. The first diffractive area further includes a hidden, not visible to the naked eye code from the arrangement in the first region (1) arranged diffractive micro-regions and / or from the structure of the first diffractive region (1) is reconstructed. Further, a method to increase the protection against forgery of a security document will be described.


Introduction:
 Obesity is associated with a varying spectrum of metabolic risk, from the metabolically healthy obesity (MHO) phenotype, to metabolically unhealthy obesity (MUO) with the development of metabolic syndrome (MetS) and diabetes (DM). The longitudinal association of metabolic risk with CVD phenotypes (CHD, HF) has not been well characterized.

 Hypothesis:
 Persistent MHO is independently associated with heart failure (HF) but not coronary heart disease (CHD), and regression from MUO to MHO mitigates CVD risk.

 Methods:
 We conducted a prospective analysis of 10,011 Visit 4 (1996-98) ARIC participants free of HF and CHD (mean age 63, 21% Black, 56% female). Metabolic risk among those with obesity (BMI ≥ 30 kg/m
 2
 ) was categorized as MHO (no MetS or DM), MUO (MetS present) and MUO with DM, with same categorizations among those without obesity. We used Cox regression models to estimate associations of cross-categories of metabolic risk status at Visit 2 (1990-92) and Visit 4 with risk of HF and CHD after Visit 4 through 12/21/19. (Reference: persistent metabolically healthy normal weight).

 Results:
 Between Visits 2 and 4, 56% of those with MHO transitioned to MUO. There were 2212 HF and 1648 CHD events, median follow-up of 20.5 years. Persistent MHO status was associated with increased risk for HF (HR:1.59, 95% CI: 1.19-2.13) but not CHD (HR: 1.08, 95% CI: 0.74-1.58) (Table). Persistent MUO with DM had the highest risk for HF (HR: 5.30, 95% CI: 4.38-6.41) and CHD (HR: 3.77, 95% CI: 3.00-4.74). Among those with MUO at Visit 2, progression to MUO with DM at Visit 4 was linked to greater risk for HF and CHD, while regression to MHO was associated with an attenuated risk for CVD. Similar patterns were seen for those without obesity (data not shown).

 Conclusions:
 Transitions in metabolic risk status are common and associated with divergent patterns of CVD risk. Progression from MHO to MUO and even persistent MHO are linked to HF risk, whereas regression from MUO to MHO may attenuate CVD risk. Primordial prevention of obesity is warranted to stave off HF.


Abstract : During the last year, we have published more than 20 research papers including 2 Science papers, 4 papers in Nature Physics and Nature Communications and 5 Phys. Rev. Letters. The most important technological result probably was the development of fabrication procedures to encapsulate graphene between boron-nitride crystals, which allows us to routinely achieve mobilities above 100,000 cm2/Vs and demonstrate room-temperature ballistic transport at micron scale (Nano Lett. 11, 2396, 2011). This development also led to the first double-layer graphene heterostructures, in which we reported interesting interaction phenomena (Nature Phys. online 2011) and which continue to be in the focus of our attention offering a wealth of new physics and potential applications. Interaction phenomena have also been studied in suspended devices made from graphene and its bilayer (Science 333, 860, 2011; Nature Phys. 7, 701, 2011) and by using the nonlocal geometry (Science 332, 328, 2011). As a result we can now routinely make and investigate complex graphene-BN heterostructures with mobilities 10 times higher than for graphene on the standard Si substrates. For suspended graphene devices, we achieve mobilities well above a million, that is, 100 times higher than for graphene on a Si substrate. Another important development over the last year was the demonstration of a graphene-based derivative, fluorographene that is a two-dimensional version of Teflon (Small 6, 2877, 2010). In all these publications, the PIs have gratefully acknowledged the AFOSR support. As concerns the entire 3-year project, it resulted in 4 Science research papers and dozens of reports in Nature series magazines, Phys. Rev. Letters, Nano Letters and other high-quality research journals. Despite the short reported period, our research has already caused very high impact that can be quantified by the number of citations for the papers supported by the AFOSR grant.


Communication media use (CMU) can benefit, but can also strain employee well-being through specific CMU-related demands. These mixed findings might be explained by conditional factors. For example, CMU may not actually result in a comparable increase of demands for every personality. In this study, we systematically study the role of personality on the effects of CMU and its demands, by means of an online questionnaire (N=663). This study supports the proposition that CMU comes with several related demands that strain employee well-being. In addition, this is the first study to show the influence of personality in a context of CMU. Except for neuroticism, all personality dimensions were found to mitigate an indirect relationship between CMU and one of its demands. We can conclude that the personality traits extraversion and openness are most helpful in dealing with the demands related to CMU.


Phosphite is increasingly being used as a means of control for dieback caused by Phytophthora cinnamomi. We wish to study the likelihood of P. cinnamomi evolving resistance to phosphite, given the clonal populations of the fungus present in Western Australia. We have collected isolates of P. cinnamomi from areas where phosphite has been used intensively for up to 15 years (avocado orchards) as well as areas of less frequent use add no use of phosphite. Our testing involved stem inoculating a clonally propagated host (Leucadendron sp.) that was treated with one of three levels of phosphite (0%, 0.25% and 0.5%). We measured the extent of colonisation by each P. cinnamomi isolate after eight days of incubation in a controlled temperature plant growth cabinet. Preliminary results suggest that less aggressive isolates are not present in populations obtained from areas where phosphite has been used. Also, the few isolates that colonise the phosphite treated host to a large extent, all come from areas of phosphite use. Research is continuing to replicate these results and investigate their significance to the control of P. cinnamomi using phosphite.


Introduction: hepatic steatosis (HS) has been previously considered as a valuable and long-established indicator for evaluation of metabolic syndrome (MetS) and cardio-metabolic risks. Recently, epicardial adipose tissue (EAT) has been proposed and up to be established to carry the same or more than of HS as regarding cardiometabolic risks. Hence, both of HS and cardiac steatosis coexist and interact with each other i.e. one reflects to the other. There are little data assessing the associations of hepatic and epicardial fat in non-metabolic-syndrome Egyptian adults. Objective: to evaluate the relationship between HS and EAT, and its relation to the components of metabolic syndrome. Patients and methods: We studied fifty HS patients accidentally discovered by abdominal ultrasound and fifty healthy matched controls with normal fat content in the liver (without HS) by ultrasound for comparison. Both groups underwent complete history taking, general examination, laboratory investigations and 2D transthoracic echo Doppler study at baseline and 18 months thereafter only for patient's group. Results: this study showed that, there is a positive correlation between HS and EAT and metabolic syndrome. HS and EAT are early and sensitive predictors for metabolic syndrome. Conclusion: hepatic and epicardial fat are early and strong predictors of metabolic syndrome.


Aliens — Expulsion of — Reasons for Expulsion — Judicial Review — Ministerial Discretion — Freedom of Thought and Association — Limits of.


The paper analyzes the possibility and expediency of recognizing robots and artificial intelligence systems as subjects or quasi-subjects of law. The author states that there are three approaches to understanding the subject matter: 1) the formal legal (positivist) approach; 2) the anthropocentric approach; and 3) the naturalistic approach Only within the framework of the latter, attempts are made to identify objectively existing features of the subject of law. At the same time, unlike a quasi-subject, the subject of law always has such a feature as freedom of will. The solution to the question of whether a robot (an artificial intelligence system) has its own will depends on understanding the concept of «will» itself, which is also far from unambiguous. The author identifies two main approaches to the concept of will: 1) the will as a manifestation of self-consciousness; 2) the will as the ability to achieve a goal. Modern robots (artificial intelligence systems) do not have self-awareness, therefore, within the framework of this approach, giving them the status of a legal entity is possible only in an indefinite perspective. The second approach to understanding the will can be applied to many already existing systems. Thus, the author states that the potential for subjectivity of robots (artificial intelligence systems) exists. However, the advantages of such a solution are not obvious in comparison with their consideration as quasi-subjects of law. In this regard, it is justified that the introduction into the legal sphere of such a fundamentally new subject of law as a robot (an artificial intelligence system) is premature. However, there is an objective need to recognize a number of them as quasi-legal entities that represent a certain legal value.


Objective: To define the reference range for Neuron-specific enolase (NSE) in serum and cerebrospinal fluid (CSF) among different ages, and explore the relatoinship of NSE levels between in serum and in CSF among both healthy children and neonates with HIE, meanwhile, to discuss various kinds of factors having influence on the result of the test. Methods: The NSE levels in serum and CSF were measured by ELISA in healthy children and neonates with HIE. Results: The NSE levels in serum and CSF didn't correlated with sex and age in 66 healthy children. The specimen collection, preservation, dose of specimen and the process of operation were found as the factors influencing the test determination. The NSE levels in serum and CSF in neonates with HIE correlated greatedly with the severity of the patient's condition (t=2.95~6.38, P 0.01). The changes of NSE levels in serum of both heathy children and neonates with HIE were very correlated to those in CSF (r=83.5~87.3). Conclusion: Since the NSE levels in children's serum and CSF have no diffences in sex and age, only one normal value is needed for all children. The change of NSE level in serum can reflect the degree of neuron injury. The determination of NSE in serum and CSF can be used to estimate the severity of HIE in children, and to direct the treatment of these patients.


Competitive state anxiety may influence performance. The cognitive component of competitive state anxiety was assessed qualitatively in the present study, in a case of semi professional soccer player. Data was collected by means of a five stage method interview. Inductive content analysis was employed to categorise and analyse the emergent themes. The participant perceived some cognition as positive and facilitative and other cognition as negative and debilitative. He has developed coping strategies to turn the latter to positive cognition. The analysis revealed six distinctive phases about his thought patterns in proximity to a match, with no relation to the intensity of these thoughts.


AIMS/OBJECTIVES: To study cases of thrombocytopenia on the basis of bone marrow findings and correlating it with clinical findings and hematological parameters. To study role of morphological examination of bone marrow aspirate in diagnosis of various disorders leading to thrombocytopenia and classify them. It was a retrospective METHODS: study on 100 patients who presented with persistent thrombocytopenia either isolated or combined with other cytopenias in tertiary care hospital in 2022. Complete clinical details were recorded. Routine hematological investigations like CBC were performed using automated cell counter. Detailed peripheral blood examination was done. The bone marrow examination was done in every case and findings were recorded. Final diagnosis was listed under 2 categories: neoplastic and non-neoplastic. A total of 100 cases were included in our study and categorized into RESULT: neoplastic and non- neoplastic. The most common neoplastic condition was acute leukemiaand most common non-neoplastic condition was megaloblastic anemia followed by ITP. Overall most common condition was megaloblastic anemia. Age distribution of patient varied over a wide range from 9 months to 83 years of age. The most common clinical feature was generalized weakness followed by progressive pallor, fever, bleeding tendencies etc. CONCLUSION We concluded that thrombocytopenia is not a disease but it is an entity which can be seen in a number of clinical problems including neoplastic and non neoplastic diseases. We also found that bleeding is not very common manifestation in thrombocytopenia and moreover few patients with very low platelet count had no bleeding manifestation


This paper mainly discusses how to develop the equipment maintain assistant decision support system on the base of detected data of the integrated detecting platform and equipment daily use records.It primarily researches the object-oriented model base system,designs the storage structure of the model base.In this structure,the model program library file,model dictionary library,and decision source data are separated from each other,but each is utilized dynamically in operation.Mean while,the management and flow mechanism for utilization of the model base management system layout is also made.


Constructive definitions of discrete random measures, which specify a sampling procedure for the weights and atom locations of the measure, have proven to be of great value in statistics and related fields. We consider the case of completely random measures and obtain a constructive representation for completely random measures on Euclidean space. For random measures on the real line satisfying a specific σ-finiteness property, the representation is equivalent to the Ferguson-Klass representation of pure-jump Lévy processes. As examples, we provide "stick-breaking" representations of the gamma process, the stable process and the beta process.


You are able not to store the credentials in the project file inside the IDE - you can get access to an org using OAuth for authentication.


What achievements had the irrigation works obtained during the Great Leap Forward? Were there any errors or disadvantages? How should we evaluate these errors and disadvantages? These questions were disputed during the Great Leap Forward, and are still at variance in academic circle at present. Generally speaking, there are two viewpoints on the merits and defects of the irrigation works during the Great Leap Forward. One declares that the advantages of the irrigation works were greater than the disadvantages though errors and failures exist indeed, which is the mainstream in academic circle. The other one asserts that the loss of the irrigation works was greater than the gain and emphasizes the major mistakes and severe deficiency despite affirming the achievements. I think denying the achievements and emphasizing the defects blindly is not consonant with the historical facts; meanwhile, emphasizing excessively the merits and not affirming the disadvantages is not realistic, either take the irrigation works during the Great Leap Forward in mass, both merits and defects existed; the achievements were the main aspect and the errors were the secondary aspect; the achievements were great; while, the lessons were profound.


The Einstein-Podolsky-Rosen (EPR) paradox is the earliest quantum paradox, which was motivated by the fundamental problem whether local realism can completely describe quantum mechanics. The EPR paradox has stimulated an important concept of "quantum nonlocality", which is classified into three distinct types: entanglement, quantum steering, and Bell's nonlocality. As two well-known quantum paradoxes for Bell's nonlocality, the Greenberger-Horne-Zeilinger paradox and the Hardy paradox have been well studied and also confirmed in experiments, however, the experimental test of the EPR paradox has not yet been reported. The EPR paradox is essentially a paradox for quantum steering. Very recently, the EPR paradox has been mathematically formulated to a contradiction equality "$k=1$", thus rendering its possibility to be directly observed in the experiment. In this work, we perform the first experimental test for the EPR paradox in a two-qubit scenario. Furthermore, by starting from the EPR paradox we can generate the generalized linear steering inequalities, which have an advantage over the usual ones by detecting more steerability of quantum states. Meanwhile, we also perform experiment to confirm this merit. Within the experimental errors, the experimental results coincide with the theoretical predictions. Our results deepen the understanding of quantum foundations.


A systematic range of closure sheet variants have been evaluated against the commercial requirements of formability, resistance spot welding, adhesive bonding and paint line compatibility in automotive manufacture. This paper considers the relative benefits of surface conditioning treatments in 3 areas; surface topography/texture, chemical pretreatment and lubrication. The need to provide a balance of properties is described with reference to selected performance data and characterisation studies. Surface analytical techniques employed in this study include, TEM-microtome sectioning, SEM, and Vertical Scanning Light Interferometry.


The purpose of this research study was to identify the causes and negative effects of employment discrimination towards Latino immigrants. Using a qualitative design the researcher interviewed nine Latino professionals on their views of employment discrimination towards Latino immigrants. Additionally, the participants have worked with the Latino immigrant community, have experienced employment discrimination themselves or know Latino immigrants who have experienced employment discrimination. The researcher analyzed data by looking for themes. Themes have been noted and compared to the literature review that has been collected on this topic. Transcripts were analyzed and reviewed to ensure validity and credibility. The findings indicated that eight out of nine participants believed that employment discrimination towards Latino immigrants still exists today. Participants discussed how employment discrimination is a form of injustice that prevents Latino immigrants from getting access to equal employment opportunities. The findings of the study also demonstrated a need for future research. The researcher encourages future research to conduct a study on the positive outcomes that may result from educating Latino immigrants about U.S. labor laws. LATINO PROFESSIONALS' VIEWS ON EMPLOYMENT DISCRIMINATION TOWARDS THE LATINO IMMIGRANT COMMUNITY 3


Subject Research Guide -- Physics (General) Search for a book from here. Also, see the listing of Chem Reference books we own.


Abstract : The invention concerns a supplementary material to increase the service distance or service life of cutting tools such as millers, drills, lathe cutters, punches, etc., and steels coated with wear-reducing cutting materials. The use of these materials is limited with respect to their thermal resistance. They are surpassed by cooling lubricants consisting of oil-soluble compounds containing in particular the elements Cl, B, and P.


This paper presents the first results from model-based TanDEM-X tomography of a structurally complex temperate forest in Tasmania. Two tomographic profiles are shown and heights estimated using three-level model inversion are compared with similar metrics from airborne lidar scanning.


Objective To compare the curative effects of different surgery incisions on mammary gland fibroma.Methods 80 patients with mammary gland fibroma who would got surgery were randomly divided into observation group(by mammary areola arc incision) and control group (by radial incision).The surgery time,blood loss,first wound healing rate,symmetry rate of bilateral mamma,satisfactory appraisement of patients,postoperative complication and tumor recurrence rate of the two groups were observed and compared.Results Compared with control group,the surgery time of observing group was significantly longer(P <0.05),the blood loss was significantly less(P <0.05),.the symmetry rate of bilateral mamma and satisfactory appraisement of patients were significantly higher(P < 0.05 or P < 0.01),and the incidence rate of postoperative complication was significantly lower(P < 0.05).But there was no difference of the first wound healing rate between the two groups (P > 0,05).All the patients were followed up for 2-56 months,and only 1 case of recurrence in each group,and there was no significant difference between the two groups (P > 0.05).Conchusion Treating mammary gland fibroma by mammary areola arc incision shows less blood-loss,maximum mamma symmetry preserving,high satisfactory appraisement of patients,low postoperative complication and does not increase the recurrence rate after surgery.

Key words:
Mammary gland fibroma; Mammary areola arc incision; Radial incision; Curative effect


K eeping C hildren S afe in C ars BY JILL COOPER Co-authors on this study include David Ragland, Director, Berkeley Traffic Safety Center; Kara MacLeod, Research Associate, Berkeley Traffic Safety Center; and Wendy Jameson, Director, California Health Care Safety Net Institute. A C C E S S


Burn injuries sustained by children appear to reduce the level of vitamin E found in their adipose tissues. The depletion of vitamin E was found to be rapid – as levels were decreased to a greater extent in only a few weeks compared with what would normally be expected in years. As well as being an important antioxidant, vitamin E carries out several metabolic functions, as well as having a part to play in the nervous and immune systems. In the investigation, published in The American Journal of Clinical Nutrition, researchers followed eight pediatric patients up to 1 year after burn injury. To examine whether 'thermal' injury decreases the store of vitamin E in the body, authors analyzed a-tocopherol levels in samples of adipose tissue. Scientists found that whilst a-tocopherol levels in the adipose tissue were "within the expected normal range" during the first week post injury, levels were shown to be "substantially lower" at weeks 2 and 3. This was despite the fact that as part of a high calorie diet, the children were given more than 100% of the recommended daily allowance of vitamin E and other nutrients.


Rhodopseudomonas capsulata chromatophores were immobilized with a co-crosslinking method. Immobilization was used as a tool for a defined modification of the chromatophore environment to study ATP production over a long period of time. The light-induced phosphorylation of ADP as a function of time was studied with chromatophores under different conditions: (a) native chromatophores with and without the hexokinase ATP-trapping system; (b) immobilized chromatophores without hexokinase, with the enzyme added in the bulk solution and with the enzyme co-immobilized in the matrix. The overall amount of ATP produced as a function of ADP concentration was studied for native and immobilized chromatophores. The global phosphorylation performed was also studied as a function of the amount of biological material used. The results can be explained by an effect of the ATP/ADP ratio. The results given by the immobilization show that the important point is not the ATP/ADP ratio in the bulk solution but the ratio value in the microenvironment of the chromatophore itself.


This chapter reports on the design refinement process of the Malaysian Studies 3 (MS3) module site from the perspective of the designer, taking into consideration the feedback from the end-users who are the learners. The learners' feedback was reviewed with the practitioners for further refinements of MS3 version releases. This study contributes to the body of knowledge in design and development research bridging theory and practice based on a real-life design-case of in Taylor's University to make the leap to Education 4.0. The study affirms that in designing for a learner-centered environment a partnership is needed between the practitioners and learners to fully understand the learner's needs. Further, continuous support from an e-Learning team must be established in a HEI, to ensure a smooth transition to leaping from the traditional into an online classroom and this is also true when designing for learning at scale (L@S). Finally, a robust LMS must be a part of the eco-system to ensure L@S can be effectively delivered.


The unitary addition Cayley graph $G_n$, $n\in Z^+$ is the graph whose vertex set is $Z_n$, the ring of integers modulo $n$ and two vertices $u$ and $v$ are adjacent if and only if $u + v \in \cup_n$ where $\cup_n$ is the set of all units of the ring. The $A_\alpha$-matrix of a graph $G$ is defined as $A_\alpha (G) = \alpha D(G) + (1-\alpha)A(G)$, $\alpha \in [0, 1]$, where $D(G)$ is the diagonal matrix of vertex degrees and $A(G)$ is the adjacency matrix of $G$. In this paper, we investigate the $A_\alpha$-eigenvalues for unitary addition Cayley graph and its complement. We determine bounds for $A_\alpha$-eigenvalues of unitary addition Cayley graph when its order is odd. Consequently, we compute the $A_\alpha$-energy of both $G_n$ and its complement, $\overline{G_n}$, for $n={p}^m$ where ${p}$ is a prime number and $n$ even. Moreover, we obtain some bounds for energies of $G_n$ and $\overline{G}_n$ when $n$ is odd. We also define $A_\alpha$-borderenergetic and $A_\alpha$-hyperenergetic graphs and observe some classes for each.


In a Turing test, a single agent (the judge, generally a human) chats with two mysterious conversation partners [1]. One of the two mystery conversationalists is a human, while the other is a computer program (a chat bot, or just bot). The bot is the entity who is actually taking the test: If the judge cannot (accurately) tell which mystery conversation partner is the human and which is the bot, then the bot passes the test (and otherwise it fails). It is easy to see that a Turing test can also be run with only a single mysterious conversation partner (whom we will call the target). To do so, the test organizer chooses a human target with probability 50% and a computer target with probability 50%. Then, after a conversation with the target, the judge is asked to report how probable she thinks it is that the target is a human--if she reports 50% or higher when talking to a bot, then that bot passes the test.


A key issue in tumor classification based on DNA microarrays is to perform gene selection due to high dim ension o f gene expression d ata. In this paper, we analyze the di sadvantages of ran k-based gene selection methods. In order to obt ain optimal gene subset for classification, a genetic algorithm based model-free gene selection method (GA-Selection) is proposed. It transforms the feature selection into a global optimal problem. Because the fitness function in genetic algorithm is defined as the ratio of bet ween-class distance to within-class dista nce, GA -Selection does not depend on a speci fic classifier. To evaluate the performance of GASelection, experiments are carried out on two binaryclass dat a s ets (leukemia and colo n) a nd one multi-class da ta set ( SRBCT). In th e experiments, the support vector machine and back propagation neural networks are used as the classifiers. The results show that GA -Selection o btains 98.61%, 91.94 % a nd 100% 4-f old cross validation a ccuracy respectively on the leu kemia, colon and SRBCT data sets res pectively, which outperforms the compared methods. GASelection ca n red uce th e number of redun dant features wi thout greatly reducing the cl assification accu racy an d it can be u sed as a n al ternative in many ot her fea ture selection problems.


In this paper,we summarized methods for identifying the authenticity and seed purity of kidney bean(Phaseolus vulgaris L.) cultivars,including plot planting identification,seed morphological identification,electrophoretic bandidentification and molecular marker identification,and we put forward feasible suggestions to provide reference for accurate and quick identification of authenticity and seed purity of P.vulgaris L.


Wearable heart rate (HR) monitors typically implement photoplethysmography (PPG) technology and are used in research as an alternative to electrocardiogram (ECG). However, questions surrounding the accuracy of PPG technology exist. To provide an answer regarding the question of accuracy, we conducted a study to compare average HR readings of two different HR technologies (PPG vs. ECG) after an interval style cardio-based workout. A total of 30 trials were conducted and average HR readings from the two HR technologies were compared using an ANOVA. Results revealed no significant difference between the two technologies. However, when HR reached around 155-160 beats per minute, a difference of +/− 5 beats per minute was observed between the two technologies with PPG HR readings being less than ECG. As a result, future research could consider the wearable PPG HR technology as accurate, but with certain experimental design implications.


The document presents an Executive Summary of a microcomputer-based Marine Diesel-Fuel Cost and Quality-Analysis/Selection Program that can be utilized to evaluate and select a fuel for bunkering on the basis of cost per unit heat content in dollars per million Btu, $/MBtu, versus the more traditional method of price per unit volume or weight, referenced to viscosity. In addition, the program evaluates and identifies, based on the pre-purchased quoted fuel properties, fuels with potentially harmful contaminants.


Tamarix arceuthoides has the bi-seasonal flowering and fructification characteristics.In this paper,the morphological features and germination of T.arceuthoides seeds matured in spring and summer are researched.The results show that there was no significant difference in the external morphological features,size and color between the seeds fructified in different florescences.Freshly-harvested seeds matured in spring and summer could germinate in a wide temperature regime range(5-15 ℃,5-25 ℃,15-25 ℃ and 25-35 ℃).The germination of spring seeds was rapider than that of summer ones,and only 2-36 hours were needed when the germination rate reached 50%.The effect of NaCl with concentrations below 0.2 mol/L on the germination of the seeds matured in spring and summer was not so significant,but the germination rate was decreased till to zero with the increase of NaCl concentration from 0.4 mol/L.After the seeds were incubated in NaCl solution for 8 days and then transferred to distilled water,the germination rate was 0,which reveals the germination capability of T.arceuthoides seeds will be lost forever if the seeds are treated with NaCl solution.Germination percentage of the seeds was decreased after the seeds were stored for 2 months under natural temperatures in laboratory.The germination capability of T.arceuthoides seeds can last for about 360 days only.


It is difficult to predict springback, torsion in particular, with great accuracy by FE simulation. In this study, the effects of anisotropic yield functions of the blank and elastic deformation of the tools on springback are investigated in order to improve the accuracy of torsional springback prediction in high strength steel part forming. The effects of anisotropic yield functions on the torsional springback in curved hat forming were compared, using parameter sets derived from various experimental methods: uniaxial tensile tests only; hydrostatic bulge tests and uniaxial tension tests; uniaxial and biaxial tensile tests. FE analysis of press forming taking account of tool deformations was carried out and the results were compared with the ones of FE simulation with rigid tools and experimental results. It is demonstrated that FE simulated torsional springback with deformable tool model has better correlation with experimental one than with rigid tool model.


A review of Goldstone , by Julie Lawson; Turns on a Dime , by Julie Lawson; The Ghost of Avalanche Mountain , by Julie Lawson.


The aim of this study is to develop an attitude scale for mathematics education courses. Researchers have determined the items of the scale by searching through the related literature, and also the expert opinion has been taken. After that, they have prepared a draft scale with 40 items. The scale has been conducted on a total of 450 prospective teachers studying at the Division of Mathematics Education and Department of Primary School Mathematics Teaching at the Faculty of Education in Hacettepe University and Balikesir University. SPSS 11.5 has been used for the analysis of research data. In consequence of the analysis, scale has been reduced to 18 items. 12 of the items are positive and 6 of them are negative. Cronbach Alpha coefficiency of reliability is 0,928. In the repeated test conducted on 51 people, the coefficiency of reliability is 0,791. In the factor analysis of validity, the criterion is one dimensional.


theories and can thus indeed be said to constitute a philosophical discourse in its own right' (194). This volume has many virtues. The range of topics covered by the papers gives a clear sense of the fecundity and technical power of du Châtelet's own mind. As a whole, the papers give the reader a good sense of her role in French (indeed, European) intellectual life of the eighteenth century. Many of the papers also suggest avenues for future research, including research that can delve more deeply and rigorously into the rich conceptual material introduced here. Reichenberger's piece seems especially open to amuch longer, deeper and sustained treatment of what promises to be a philosophically very satisfying analysis. Similarly, Winter's indication that the Institutions constitutes 'a philosophical discourse in its own right' urges a careful and sustained philosophical treatment of that work. Nagel's discovery and close treatment of du Châtelet's Essai is an important and exciting moment in du Châtelet scholarship. Themassive, 40-page bibliography is also extremely helpful, not to mention indicative of the fact that du Châtelet's work is finally beginning to gain the attention it deserves. The volume is, however, frustrating at times. As indicated, the bulk of the papers will be less interesting to one keen on sharp, close, careful and creative philosophical interpretation, analysis and criticism. This is no fault of the volume; it is, after all, a volume in the history of ideas, and on that score, it certainly delivers. But du Châtelet's corpus is itself so philosophically fertile and exciting that the time is now ripe for scholars to plumb her thought for its philosophical riches. To that end, this volume will certainly contribute relevant historical context that will help to make future philosophical work especially rich. More germane are the frustrations that arise due to the sometimes clumsy translation and to the often careless editing and proof reading. There are far too many ungrammatical, or otherwise awkward, sentences to make this a fluid read. These flaws aside, it is heartening to see the writings of Emile du Châtelet gaining the attention they have deserved these past two and half centuries.


Few believe that the European Union will meet its 2010 renewable energy targets, but its efforts so far have not been without merit. New policies and technologies should see the use of renewables grow in importance over the next decade.


Normal Sleep Patterns (1) Two kinds ojsleep It is generally recognised that there are two qualitatively different kinds of sleep which alternate throughout the night in normal healthy individuals. These are the non-rapid eye-movement (NREM) sleep or orthodox sleep and the rapid-eye-movement (REM) sleep or paradoxical sleep. By means of electro encephalography (EEG), electrooculography (EOG) and electromyography (EMG), different stages of sleep have been defined according to a standardized scoring system (Rechtschaffen and Kales, 1968). NREM sleep is further classified into stages 1, 2, 3 and 4, which show a graded decrease in autonomic activities and an increase in depth of sleep. Stage 4 sleep is therefore the deepest stage and together with stage 3 is often referred to collectively as slow-wave sleep (SWS). Characteristically the first appearance of SWS after the onset of sleep nearly always coincides with a surge of growth hormone level in the blood. On the other hand, REM sleep is characterized by bursts of rapid eye movements (or REM activity), abolition of tone in many skeletal muscles, heightened but variable autonomic activities, and a low-voltage mixed frequency EEG pattern resembling that of stage 1 sleep. In animals, spike discharges can be recorded in the regions of pons, lateral geniculate nucleus and occipital cortex (PGO spikes) just pre ceding or during REM sleep. When a subject is awakened from REM sleep, he often reports dreams charged with emotions, in contrast to reports of mental activity obtained from most NREM awakenings which have the quality of thoughts. Under normal circumstances adult indivi duals sleep from 7 to 8 hours each night, 20—25 per cent of which will be spent in REM sleep. A normal night's sleep usually begins with NREM sleep, from light to deep stages, which is interrupted about every 90 minutes by a period of REM sleep. Thus NREM—REM sleep cycles alternate throughout the night, and there are 4—6such sleep cycles each night. In general, NREM sleep tends to predominate in the beginning of the night, whilst the REM sleep period becomes more prolonged as the night progresses.


The fault analysis for the electrostatic parallel-plate is a critical issue in the design flow, as it played an important role in determining device reliability and the voltage required for successful operation. The simulations for pull-in and release voltages were carried in CoventorWare. The FEM model was constructed. The displacement of the upper electrode and corresponding capacitance between the upper and bottom electrode at different voltage are studied. The contact force and the stresses in the movable structure were presented. Electrostatic spring softing analysis interpreted the shift at the resonant frequencies.


The first lateral two-zone reduced surface field MOSFETs in 4H-SiC with NO annealing are reported. Interface properties of 4H-SiC-SiO are improved, with inversion layer field-effect mobility increased to 25 cm V s, five times higher than that of dry reoxidation process, and with channel resistance significantly reduced. Devices are normally off with low leakage current. Threshold voltage is around 3 V. Blocking voltage of 930 V and specific on-resistance of 170 m cm were obtained. Large-area devices with multifinger geometry are also demon- strated with scaled-up current. The output characteristics exhibit excellent linear and saturation regions. Index Terms—Field-effect mobility, field-effect transistors, in- terface, MOS, NO annealing.


Objective To assess the value of plug mesh tension free hernia repair in the treatment of abdominal external hernia. Methods 123 tension free repairs of hernia in 115 patients performed in our hospital from April 1988 to May 2000 were retrospectively reviewed. 50 4% (58/115) of cases were complicated by diseases such as cardiopulmonary dysfunction, hypertension, diabetes mellitus, prostate hypertrophy, cirrhotic ascites and thrombocytopenia. Results All patients had healing by first intention with no incisional infection or death , and they were discharged 3~7 days after operation(90% of patients were discharged 3 days after operation).90 4% of patients were followed up with an average of 20 months (1~25 months). There was no recurrence during the follow up.Conclusion Plug mesh tension free repair has the advantages of less trauma, little postoperative discomfort, rapid recovery and low recurrent rate.


Abstracts. Ionic transport properties and diameter of asymmetric conical nano-pores in polyethylene terephthalate membranes were calculated. These nano-pores were synthesized by chemical etching method in irradiated polyethylene terephthalate (PET) films. After etching, the transport characteristics weredocumented under stepping voltage with 2M ionic concentrations of Potassium halides i.e. KCl, KBr and KI. The symmetric bathing condition (same temperature and same pH value solution in both side of chamber) in electrochemical cell were accomplished. It is investigated that diameter of nano-pores is also evaluate by measuring the current rectification properties of track etched nano-pores.


Transmission losses in two different size groups of step-bar ultrasonic solid horn are tested by using 2.5MHz ultrasonic transducer,and the ultrasonic echoes are attained under the same test condition.The time domain ultrasonic echoes are sampled with digital oscilloscope.And then,on the basis of the Fast Fourier Transform(FFT) theory,the signal of ultrasonic echoes and the power spectrum are attained.After comparison and analysis,the preliminary patterns of ultrasonic energy transmission losses in the solid horns at their resonance frequency are gained.Furthermore,the hypostasis of magnification factor of a solid horn is explained.The method of ultrasonic energy transmission losses in more complex and different type solid horns is offered in this paper.


Background: Myricetin (MCN), a dietary flavonoid, is present in walnuts, fruits, vegetables, tea, and berries and has been suggested as an anti-inflammatory, antiplatelet, antimicrobial, antioxidant, and antiviral drug. Objectives: This study aimed to investigate whether the necroptosis pathway involves the toxic impacts of myricetin (MCN) on the colon adenoma-carcinoma HT-29 cells. Methods: For 48 hours, HT-29 cells were exposed to 50 µM MCN or three mM Nec-1 (Necrosatine-1, a necroptosis preventive). Apoptosis, cell viability, and expression of necroptosis-related genes, including MLKL (mixed lineage kinase domain-like protein), RIPK1 (receptor-interacting protein kinase-1), and RIPK3, were evaluated. Results: MCN caused a noticeable decline in the survival of HT-29 cells. In contrast to the slight change in the apoptosis index in HT-29 cells, MCN considerably increased the necrosis index. MCN could enhance the expression of MLKL, RIPK1, and RIPK3 in the HT-29 cells. The co-treatment of MCN with Nec-1 resulted in a significant elevation in HT-29 cell survival. Nec-1 could decrease the necrosis index and expression of necroptosis-related proteins in the MCN-exposed HT-29 cells. Conclusions: These findings demonstrated that MCN effectively induced cell death in HT-29 cells by activating the necroptosis pathway.


One of the by-products of the literature which followed the publication of Phillips's (1958) well-known paper was the development and elaboration of models of individual behavior in labor-market disequilibrium (see Phelps [1969] for a survey). In retrospect this may be the most significant consequence of the Phillips curve analysis, since the labor-market models may suggest ways for tackling the wider problem of the adjustment to equilibrium which is still in a very messy state. In this paper we shall consider one aspect of the problem which has been neglected by the "new microeconomics," namely, the implications of attitudes toward risk for individual behavior in disequilibrium. Section II introduces the concept of a risk premium which is then used in Section III to analyze the relationship between individual behavior toward risk, job search, and the structure of wage offers by firms. Sections IV and V consider the relationship between the distribution of risk attitudes and the distribution of income and wealth among individuals. A concluding section points out some of the implications of the analysis for empirical research.


The economic crisis hit Indonesia since mid 1997and has brought unfavorable changes in almost all aspects ofnational life. This crisis is a situation that could occurs in several financial institutions and losing value of their assets. However, financial institutions such as banks can be predicted its bankruptcy using bankruptcy prediction model. This study aims to know how total assets and the firm size impact bankruptcy prediction model, compare the bankruptcy prediction model, and to know which one is a better model.
Bankruptcy prediction models for banking that used by author are Altman, Zmijewski, and Springate. Author is having the sample with purposive sampling technique. Samples taken are listed banking companies on BEI for its financial year 2007-2010. To know bankruptcy prediction, author use proxy of firm size and total assets with dummy regression.
The results showed that the total assets does not affect the bankruptcy prediction model directly but requires another variable, and the Altman model can decide bankruptcy better which applied at large companies or small companies.


The memoirs of a Polish communist of Jewish origin focusing on his participation in the Spanish Civil War and his post-World War II life and activities in communist Poland.


In order to prevent a crack from occurring from an impact in an interlayer insulation film below a bonding pad, provided is a bonding pad wherein small-diameter metal plugs (14a) and large-diameter metal plugs (14b) are positioned between a first metal film (12) and a second metal film (15) which is a topmost layer, and depression parts (17) are disposed in the surface of the second metal film (15) above the large-diameter metal plugs (14b).


The purpose of this study is to investigate the impact of individual characteristics on employee performance of millennial employees. Furthermore, the study was also to test the moderating effect of training on the impact of individual characteristics on employee performance of millennial employees. This research was conducted from six business entities in Yogyakarta which were engaged in media and information technology sectors. This research used saturation sampling. Primary data was obtained by circulating questionnaires to 250 millennials employees, but only 118 questionnaires were returned. The data were analyzed with PLS-SEM using SmartPLS 3.00 application. The result revealed that individual characteristics have a positive and significant impact on employee performance of millennial employees. Furthermore, training cannot moderate the impact of individual characteristics on employee performance. From these findings, we need to underline that the millennial employee's performance would increase if millennial employees increased their individual characteristics in their working activity. © 2020 by the authors. Licensee SSBFNET, Istanbul, Turkey. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).


Taking key sections landscape shaping in Yongning ancient guard city as an example,try to make scientific system ancient village landscape analysis from natural landscape,material cultural landscape and non-material cultural landscape three aspects as guiding theory of methodological awareness method,expression method and practice method,and put forward some means about ancient village landscape protection methods,so as to achieve the eternal goal of taping valuable landscape factors of ancient Yongning city.


Objective To
investigate the infectious status of the HGV in the population of Zibo Shangdong. Methods Two
sets of primers in noncoding region were designed according to the HGV genomic sequence
reported by the foreign press. 531 cases of hepatitis A,B, C, D,E and blood doners were tested
by RT-PCR. Results The positive rates of HGV RNA of the cases with hepatitis A,B,C,D,E and
blood doners were 2.2%,14.1%,21.1%,11.8%,1.4% and 6.7% respectively. Conclusion The
infection of HGV mostly co-existing with HBV and HCV could be found in Zibo of Shandong
province which showed that the HGV is mainly transmitted by blood. [


1.0 INTRODUCTION Information is a vital and an indispensable component of any academic environment. It makes for effectiveness in any academic system. Both faculty and students need to use information daily in their various academic endeavors. For decades, faculty and students have actively used the library and its resources as their main information source. Alemna, (2000) states that for centuries libraries have served as repositories of information and knowledge that have provided the vital underpinnings for socio- economic, political and cultural development in any civilization. Their relationship with cultural progress has been so interdependent that it is needless to argue whether man's cultural advancement merely produces libraries as by product. According to Robinson (2006) simplistically, libraries and archives came into being to provide a central location for hard-to-find, scarce, expensive or unique material. Scarcity of information is the basis for the modern library. In countries where information continues to be scarce, a library's role is still unambiguous. In some countries where access to information is now akin to access to electricity or water, the reason to have freestanding storehouses of a subset of all information is harder to articulate. Libraries in such countries can provide access to more information than any user could want or need. Rangathan's rule "for every reader, his or her book," might be now redefined as "for every reader, huge amounts of free-floating content, anywhere, anytime. We now live in the information age where access to many Internet resources is just a few clicks away. The Internet is a technology, which has gained more popularity in many countries across the world and Ghana, is no exception. The Internet as a medium of communication and source of information has enabled students, researchers, business information seekers and information professionals to access information to enhance their work and communicate effectively. Robinson (2006) states that in 2004, seventy million American adults logged onto the Internet in a typical day. Over 95 percent of U.S. public libraries provided Internet access. Students, many faculty, and laypeople turn to online information sources before print or the library. As a result, library use, especially for walk-in reference questions and preparation for school and college reports has declined. 1.1 Statement of the Problem The University of Ghana has a number of libraries on its campus. The Balme library is the biggest and the central library of the University. In addition to the Balme library there are various departmental, school, institution and hall libraries on campus. The collections of these libraries are subject specific. Almost all the departments under the faculties and schools of the university have their own libraries. The University gained full Internet connectivity in the early part of 1998 to enhance the opportunities available to the academic community Alemna and Adanu, (2005). The Internet was not meant to do away with research in the library. Although the Internet has a lot of advantages, it cannot be compared with that of the traditional sources. Graduate students have adopted and continue to use the online information retrieval for their academic and research work at the expense of or without considering the importance and the quality of the traditional information centers as observed by the researcher. However, merely using the Internet was not guarantee quality and good information. Even though the Internet has large amount of information, the relevance, quality, and authenticity should not be neglected. The question to ask then is why do the graduate students continue or preferred using the Internet to the library as sources of information? Should the importance, quality, and authentic information derived from the library be relegated in place of the Internet? …


The scientific and healthy development in adult education must be based on the Scientific Concept of Development.The combination of the Scientific Concept of Development and adult education is of great significance for indivduals and the society.Thus it bears social consequences and practical implications.We should understand the essence of the Scientific Concept of Development and come up with a series of strategies to promote adult education.


How well do Bongaarts's and Hobcraft and Little's methods estimate the fertility-reducing impact of the proximate determinants of fertility? Since we cannot observe what the methods estimate (i.e. fertility in the absence of the inhibiting factors), reproductive histories of a population of women are simulated to learn what the quantities are that the methods can only estimate, the 'true' values of Cm, Cc, Ca and Ci. When fertility behaviour is random, both methods work well; however, under more realistic conditions the methods go awry. Neither method works well when women employ stopping behaviour once they have achieved their desired family size. While the simulations do not attempt to incorporate the innumerable complexities of fertility behaviours, the incorporation of the simplest family-building strategy leads to the unambiguous conclusion that the methods yield poor estimates of the fertility-reducing impacts of marriage delay, contraceptive use, and induced abortions.


The current ESC/ESH-Guidelines for the treatment of arterial hypertension (AH) recommend initiation and escalation of medical treatment using renin–angiotensin–aldosterone system (RAAS) blocker, diuretics (D) and/or calcium channel blockers (CCB). They also recommend a single pill (SP) regimen to improve persistence, to increase blood pressure control and to reduce cardiovascular events.

 Data showing an advantage for a SP regimen compared to the identical loose combination (LC) regarding all these parameters in a single study are missing. We report now the results comparing SP with identical LC regarding persistence and cardiovascular outcomes in daily practice.

 This was a retrospective, non-interventional analysis of an anonymized claims dataset covering patients suffering from cardiovascular diseases insured by the German AOK PLUS public health insurance in the years 2012–2017. Patients at age ≥18 years with an indication for the use of a combination of RAAS-blockers, D and/or CCB as SP or identical LC were followed up for 1 year. After 1:1-Propensity Score Matching (PSM) persistence (defined as redemption of prescription with a lack >60 days) and clinical outcomes were compared using non-parametric tests.

 After PSM, baseline characteristics were comparable between SP and LC groups. Each group included 10,801 patients with valsartan/amlodipine, 1,026 with candesartan/amlodipine, 1,823 with amlodipine/valsartan/hydrochlorothiazide (HCT), and 15,349 with ramipril/amlodipine as SP or identical LC. 8 clinical outcomes were compared for each combination. Persistence to treatment was significant higher in the SP group. In 27 of 32 comparisons a significantly lower Incidence Rate Ratio (IRR) was identified for SP. This was confirmed by time-to-event-analysis. The largest patient group (ramipril/amlodipine) showed a significant lower risk for SP observed for stroke (IRR=0.746; 95% CI 0.627–0.886; p<0.001), transitory ischemic attack (IRR=0.693; 95% CI 0.496–0.963; p=0.023), myocardial infarction (IRR=0.623; 95% CI 0.493–0.784; p<0.001), coronary artery disease (IRR=0.579; 95% CI 0.462–0.723; p<0.001), heart failure (IRR=0.468; 95% CI 0.409–0.534; p<0.001), all cause hospitalization (IRR=0.670; 95% CI 0.652–0.687; p<0.001), cardiovascular hospitalization (IRR=0.596; 95% CI 0.519–0.685; p<0.001), and all cause mortality (IRR=0.526; 95% CI 0.463–0.596; p<0.001) compared to LC.

 A SP regimen improves persistence to medication, reduces cardiovascular events and total mortality compared to identical LC. The results of the START study strongly support the use of a SP concept in the AH medication treatment as recommended by the current ESH/ESC-Guidelines for the treatment of AH.

 Type of funding source: None


In the sixth ucchvāsa of Daṇḍin's Daśakumāracarita the hero-narrator of the chapter, Mitragupta, eventually happens to land on an island; here he climbs a fine mount and delights in the waters of a little lake. Thus refreshed, however, he is faced with a fearsome rākṣasa that dwells on the shores of the lake and that challenges him with four questions, threatening to devour him if he does not give the right answers. Of course, Mitragupta comes up with the answers, adding that, as examples of his statements, the stories of four women could be cited, and mentioning their names. The rākṣasa then asks him to tell their stories, and so Mitragupta's narration begins. Naturally, this is a way to bring four additional tales into the text; each is set in a different place in India and presents characters whose moral standards are not of the highest, except for the second story. The point of this tale, which is set in present-day Tamil Nadu, is to illustrate the rākṣasa's question 'What makes a householder's happiness and well-being?' (kiṃ gṛhiṇaḥ priyahitāya), and Mitragupta's reply, 'The wife's qualities' (dāraguṇāḥ), the protagonist being a girl who is a paragon of virtue, named Gominī.1 The tale dwells in particular on a description of the girl's beauty and how she prepares a meal in accordance with the solid principles of domestic economy, which qualifies her as an ideal bride. The tale probably originated from some traditional source, for a similar story is narrated in the Mahāummagga Jātaka (Cowell 1907, 156-246), where the bodhisattva puts a young woman to a similar test with the prospect of becoming his bride. However, apart from certain undeniable affinities between the two narratives,2 as a whole and in the details the tale of


Subtle emotions and their expression often arise in the context of managing involvement levels and turn-taking in task-oriented interactions. This paper presents some thoughts regarding their importance for eective and efficient interaction, their essentially real-time nature, and their relation to social conventions.