Based on Indonesian Muslim Travel Index, there are five of the best halal tourism destinations in Indonesia, namely Lombok, Aceh, Riau Islands, Jakarta, and West Sumatra. This research specifically examines Jakarta because of its uniqueness. This study aims to examine the Islamic attribute values and destination reputation toward revisit intention to Jakarta's halal tourism. The research design uses a quantitative approach. The unit of analysis and observation are international Muslim tourists visiting Jakarta. The questionnaire was given to a sample of 100 international Muslim tourists visiting Jakarta.  The analytical tool used to test hypotheses is Partial Least Square. The hypothesis testing results indicate that the increase in revisit intention to Jakarta's halal tourims destination is more dominantly built by destination reputation, followed by Islamic attribute values. The results of this study have implications both theoretically and practicallyIslamic attribute values that include Islamic physical attributes and Islamic non-physical attributes.


OBJECTIVE
To quantify the effect of Medicaid expansions on office-based care among the newly eligible.

DATA SOURCE
2008-2014 Medical Expenditure Panel Survey.

STUDY DESIGN
The main sample is adults age 26-64 with incomes ≤138% of poverty who were not eligible for Medicaid prior to the Affordable Care Act. For this population, difference-in-differences linear probability models compare utilization between expansion and nonexpansion states and between 2008-2013 and 2014.

EXTRACTION METHODS
Medicaid eligibility is simulated using data on family relationships, state of residence, and income.

PRINCIPAL FINDINGS
Relative to comparable adults in nonexpansion states, newly eligible adults in expansion states were 9.1 percentage points more likely to have any office-based primary care physician visit in 2014, a 21.4% increase from 2013 (p-value = .004); 6.9 percentage points more likely to have a specialist visit, a 25.2% increase from 2013 (p-value = .036); and 5.1 percentage points more likely to have a visit with a nurse practitioner, nurse, or physician assistant, a 34.5% increase from 2013 (p-value = .016).

CONCLUSIONS
State Medicaid expansions in 2014 were associated with greater likelihoods of visits with a variety of office-based providers. The estimated effects are larger among newly eligible compared with previous estimates on broader populations of low-income adults.


Many species have suffered changed habitable area due to recent climate change or/and human activities. Brandt's vole (Lasiopodomys brandtii) is same as it.The species is undergoing a continuous habitat change as a consequence of the human's production, climate change and retrogressive succession of grassland ecosystems. The distribution of the Brandt's vole was update in China and Mongolia. Based on the historical distribution map, which was made by overlaying the historical data with vegetation type's map of the grassland resources in China and Mongolia. And the distribution map was modified according to the on-site investigate data in recent years. The current species' distribution was range Hulunbei'er, northern Xilinguole, which comprise a landscape through the east of Dornod Aimag, Mongolia, and southern Hunshandake Sandy Land in China which just includes the areas around the Zhengxiangbai Qi. There were no the species in the east of Daxinganling Mountains, Liaoning, Shanxi province and Xinjiang Uyghur Autonomous Region of China. The species' distribution is discontinuous in Mongolia, including western, middle and eastern Mongolia. The western distribution along Hangay Mountains and extends for the west, the northern boundary extended to between Ider river and Chulouk river. Southward reaches of the Malhin along the plain between Hangay Mountain and Altay Mountain. The middle and east of the species' range lie in the part areas of Tov, Hentiy, Dundgovi, Dornogovi. extends to Hulunbei'er and northern Xilinguole eastwardly and southwardly respectively, northward reaches of the Trans-Baikalia, Russia. Mongolian Journal of Agricultural Sciences Vol.13(2) 2014: 88-95


The secondary structure of ribonucleic acid (RNA) is more stable and accessible in the cell than its tertiary structure, making it essential in functional prediction. Though deep learning has shown promising results in this field, current methods suffer from either the post-processing step with a poor generalization or the pre-processing step with high complexity. In this work, we present RFold, a simple yet effective RNA secondary structure prediction in an end-to-end manner. RFold introduces novel Row-Col Softmax and Row-Col Argmax functions to replace the complicated post-processing step while the output is guaranteed to be valid. Moreover, RFold adopts attention maps as informative representations instead of designing hand-crafted features in the pre-processing step. Extensive experiments demonstrate that RFold achieves competitive performance and about eight times faster inference efficiency than the state-of-the-art method. The code and Colab demo are available in github.com/A4Bio/RFold.


This chapter describes how it is important to first have some basic understanding of the intended role of social policy in advanced industrial societies in order to understand the relevance of looking at transport from a social policy perspective. The chapter offers a brief overview of the main focus and interests of social and public policy as an academic discipline, especially for those who may be unfamiliar with this. The chapter then takes the reverse perspective to look at the role of transport in modern societies and it examines the transport policy-making tradition. The last section of the chapter identifies some additional reading in both of these areas for those who may which to further pursue this line of inquiry.


Management of pain following dehorning and castration is a significant challenge for veterinarians. Physiological effects such as peripheral vasoconstriction and increased heart rate are associated with pain and distress. These effects may alter the pharmacokinetics of parenterally administered sedative-analgesics.


The article is devoted to the analysis and historical and comparative analysis of scientific data on the underground cults of Islam and Christianity. The content of scientific conclusions concerning the arrangement and activity of underground prayer places of the world's leading religions, their similarities and features in spiritual traditions is revealed. The use of a historical-comparative approach in research on the history of the formation of underground prayer places in the experience and knowledge of world religions determines their common features and similarities. When clarifying the history and time of construction, the functioning of religious underground prayer places, methods of research of theological science were used, which make it possible to accurately determine the typological function of the object, reveal the content of the religious and spiritual activity of underground prayer places, and determine their impact on the social and social environment. Presented for scientific circulation with an analysis of the traditions of worship and architectural similarities and features of religious temples in the world's leading religions.


The new irrigation techniques with higher water application efficiency should replace the commonly used traditional methods of irrigation in order to increase agricultural production for compensating the decrease of land and water resources, largely allocated to municipal and industrial usage. To this effect, a new innovation for deficit irrigation, called "partial root-drying" (PRD) practice, is promoted in recent years. In PRD technique, irrigation water quantity applied normally under the traditional irrigation practices is reduced in a certain portion, wetting only halves of plant roots and leaving other halves dry. In the following irrigation, the other halves get wet. In this way, the aim is to use limited water resources more efficiently; similar to what is achieved with the traditional deficit irrigation practices (Kang et al., 1998). In the PRD technique, while halves of the plant roots were wetted, the other halves were relatively left dry. According to PRD practices, plant roots were divided into two parts and each was grown in separate pots. Plants could keep growing while watering only one of the pots, and leaving the other dry. Under such cases, stomas are relatively closed and thus evapotranspiration reduces (Zhang et al., 1987; Davies and Zhang, 1991). It was suggested that the closure of stomas when halves of the roots were exposed to drought is controlled via chemical signals transferred from roots to the leaves (Davies and Zhang, 1991; Tardieu and Davies, 1992). While these signals reduce vegetative growth of the plant, they stimulate generative growth. In the case of wetting only halves of the roots and leaving the other halves dry, the abscisic acid concentration in xylem elements increases and causes stomatal closure (Stoll et al., 2000). The change in root water potential and rise of pH in xylem were other signals shown to be effective in controlling stomatal closure in leaves (Wilkinson and Davies, 1997). In numerous studies reported on the field-PRD-irrigation technique, only one species of plant was used. Different responses of plant species to different deficit irrigation practices were not focused on. Although Kang et al. (2000) and Kirda et al. (2005) used the same plant species in their work, their reported maize-crop-yield results obtained using PRD irrigation were different possibly due to the different climatic and soil characteristics. In this study, the response of five different maize species were studied under the traditional deficit and PRD irrigation technique, to investigate the hypothesis that maize crop yield response to different modes of deficit irrigation (i.e., DI or PRD) may genetically be controlled. Partial results such as yield, irrigation water-use Pak. J. Agri. Sci., Vol. 54(1), 209-216; 2017 ISSN (Print) 0552-9034, ISSN (Online) 2076-0906 DOI: 10.21162/PAKJAS/17.3938 http://www.pakjas.com.pk


Part 1 Nursing practice, knowledge and education: nurse education - a social and historical perspective, David O'Brian and Don Watson nursing knowledge - a critical evaluation, Jan Reed and Susan Procter teaching reflective practice - possibilities and constraints, Susan Procter and Jan Reed. Part 2 Basic skills and knowledge: an information retrieval and analysis package, David O'Brian and Graham Walton a statistics, Bob Heyman and Stephen Campbell an information technology package, Joan Aarvold, Bob Heyman and Brian Bell. Part 3 Practicums: teaching interpersonal and communcation skills, Jan Reed teaching research methods, Jan Reed and Susan Procter. Part 4 Reflectice exercises: critical incident technique, Ann Smith and Jacqui Russell clinical studies assignment, Jan Reed and Susan Procter learning diaries, Joanne Bennett and Mike Kingham. Part 5 Assessing reflective practice: assessment of reflection, Susan Procter and Jan Reed assessment of reflective practice, Jan Reed and Susan Procter future developments in nurse education, Jan Reed and Susan Procter.


Limited data exist regarding feeding pediatric patients managed on non-invasive respiratory support (NRS) modes that augment oxygentation and ventilation in the setting of respiratory failure. We conducted a retrospective cohort study to explore the safety of feeding patients managed on NRS with acute respiratory failure secondary to bronchiolitis. Children up to 2 years old with critical bronchiolitis managed on RAM, CPAP, or BiPAP were included. Of the 178 eligible patients, 64 were reportedly NPO while 114 were fed (EN). Overall equivalent in severity of illness, younger patients populated the EN group, while the NPO group experienced a higher incidence of intubation. Duration of PICU stay and NRS were shorter in the NPO group, though intubation eliminated the former difference. Within the EN group, ninety percent had feeds initiated within 48 hours and 94% reached full feeds within 7 days of NRS initiation, with an 8% complication and <1% aspiration rate. Reported complications did not result in escalation of respiratory support. Notably, a significant improvement in heart rate and respiratory rate was noted after feeds initiation. Taken together, our study supports the practice of early enteral nutrition in patients with critical bronchiolitis requiring non-invasive respiratory support.


Inthis paperaformalverification oftheLook-Aside Interface usingMDG-basedmodelchecking technique is presented. MDGs (Multiway Decision Graphs)arean extension ofBDD-like datastructures witha distinction of concrete sorts andabstract sorts. TheLook-Aside Interface isa memory-mapped interface, targeted atdevices thatoffload certain tasks fromanetwork processing unit. A synthesizable RTLmodelinVerilog hasbeendeveloped fromthestandard specification oftheLook-Aside Interface withthedesign properties specified ina CTL-like specification language called LMDG.AnMDG modelwasalsobuilt inMDG-HDL language, aProlog-style hardware description language, from theRTLmodel. Finally LMDGproperties werechecked against theMDG-HDLmodel intheMDG modelchecker. Through our experiments, weshowedapractical example ofafull formal verification using MDGs.


We present a comparative study of the low-dimensional compounds αand β-TeVO4. Our data clearly show that the change in the local coordination geometry of V ions comparing αand β-TeVO4 leads to a drastic differences in the magnetic properties. Despite sharing the same crystal structure, the two compounds realize different magnetic exchange topologies. Both compounds exhibit a transition from ferroto antiferromagnetic correlations with decreasing temperature. This effect however is driven by different mechanisms for both compounds. Additionally, a dimensional crossover is found in β-TeVO4.


Every child with Down's syndrome is a cause of grief and concern to his parents and creates problems for his family. A major purpose of counseling in cases of mongolism, as in other handicapping conditions, is to help the parents develop positive attitudes toward the affected child that will enable them to deal constructively with the problems which arise and to provide an environment in which each offspring, affected and unaffected, will have the opportunity to develop his capacities to the fullest. In most cases, this can be accomplished through proper orientation of the parents in regard to the cause and nature of the condition, including prognosis, potential role of the family in the care of the subject, and the availability and use of community services and facilities, and through supportive therapy. In developing management programs for the mentally retarded and related family counseling and guidance procedures, much emphasis has been placed on the intuitive approach and only occasionally has the superiority of one particular method or concept been documented. Of course, the same may be said for child rearing and educational practices for normal children. The purpose of this paper is to present the more prevalent management and counseling concepts in mongolism. These principles represent the cumulative experience of many workers in this field and the basic philosophy that has been put forth by several noted authorities with wide experience with Down's syndrome patients.1-3 Whenever possible, supporting studies or surveys will be mentioned. Due to the complex nature of the problems which arise in most cases of mongolism, it is apparent that effective counseling will require a variety of professional advisors including, at various times, the pediatrician, social worker, nurse, psychologist, psychiatrist, educator, and clergyman. It is generally agreed that the role of any counselor should be informative, interpretive and supportive and that the responsibility of making decisions regarding the child's general care should be left to the parents. For effective decision-making, the parents will require much information regarding the condition, their child, and possibilities for his care.4 Interpretation of this information in light of family and other environmental factors is usually required. Frequently, attention must be given to the emotional problems of the parents and siblings and, occasionally, psychiatric therapy for a serious mental disturbance may be indicated. Because of the clinical variability in Down's syndrome patients and differences in their families and available services and facilities, management and counseling must be individualized. Counseling should be available to the family not only when crises arise but on a continuing basis, so that serious problems and potential crises may be anticipated and possibly prevented. Continuing guidance is also needed, since the most suitable management for the patient will change with age and as new individual and family problems arise or as new provisions for his care are developed, The usefulness of group counseling for parents of mongoloids has been described by Giannini and Goodman.5


This paper examines the impact of government effectiveness on the socio-economic development of eight South Asian countries by employing balanced panel data from 1999 to 2018. Random effects, ordinary regression, general trends are used to understand the impact of government performances. The empirical study confirms the insignificant effect of government effectiveness on the Human Development Index (HDI) as a measurement of socio-economic development. Conversely, good governance as a whole has a positive impact on HDI as well as per capita GDP growth rate. The study also indicates a puzzle of how a country or region having poor governance performs better in different socio-economic indicators.


In the last two decades, functional magnetic resonance imaging (fMRI) has become an important and widely used imaging technique for functional brain mapping. However, blood oxygen level dependent (BOLD) technique is quite insensitive and task invoked BOLD signal change at 3T is typically in the order of a few percent. Furthermore, the coupling between BOLD signal changes and neuronal activities is quite complicated, involving a cascade of events remaining poorly understood even today. In this thesis, some of the basic characteristics of the BOLD signal are investigated. Better understanding of the BOLD signal characteristics can be beneficial for the design of BOLD fMRI experiment aimed to improve the time efficiency. It can also provide guidelines for developing fMRI data processing strategies. In study I and II, a single-shot dual-echo spiral acquisition technique was used for characterizing the T2* changes associated with motor activation task. In study I, the optimal strategy for head motion correction was investigated. Based on the improvement in the detection of brain activation, the best strategy is to perform the head motion correction using the imaging data from the second echo and then apply the derived motion correction parameters to the first echo, instead of conducting motion correction of the individual echoes independently. In study II, several aspects of brain mapping methods based on T2*-weighted imaging and T2* (R2*=1/T2*) mapping were quantitatively compared, including the detected activation volume, functional contrast, signal-to-noise ratio, and contrast-to-noise ratio. fMRI studies based T2* mapping have the following potential advantages: maximum functional contrast, independence of echo time; and reduced inflow effects. The sensitivity for brain activation detection is significantly correlated with the contrast-to-noise ratio, which is determined by both the signal-to-noise ratio and functional contrast. In study III, the hemodynamic responses to functional activation were characterized using T2*-weighted BOLD imaging, arterial spin labeling, and bolus tracking of MRI contrast agent. In addition to the BOLD signal change, the relative cerebral blood flow and cerebral blood volume associated with brain activation were independently determined. In study IV, the characteristics of the global signal in resting-state fMRI were investigated. It was found that the global signal time courses and regional contributions differ individually. However, after removing the contribution from the cerebral spinal fluid, a consistent brain network responsible for the remaining global signal changes was identified. The involved brain regions include: posterior cingulate cortex, precuneus, superior temporal gyrus, medial frontal gyrus and the cerebellar vermis, which is likely to be related to the perception and cognitive processes of the brain occurred in the specific environments during resting-state fMRI. © Tomas Jonsson 2012 ISBN 978-91-7457-627-6


Abstract We study the integration/segregation problem from the viewpoint of complex networks, but considering that the network topology is not static but there is an adaptive mechanism acting on the links. Our goal is to identify under which conditions network synchronization occurs and what structural properties are present in the network topology when this happens. In particular, we experimentally compute the main descriptive structural properties of the network when it has been modified with the proposed mechanism, and it is elucidated the relationship between these results and the observed synchronization at both the local and global scale. Our main finding is that modularity, a global feature, can naturally emerge in a network when evolving links are considered, that is, by means of dynamical properties at the local scale.


Electrooxidation of methanol in sulfuric acid solution was studied using Pt, Pt/Ni(1:1 and 3:1), Pt/Ru/Ni(5:4:1 and 6:3.5:0.5), and Pt/Ru(1:1) alloy nanoparticle catalysts, in relation to methanol oxidation processes in the direct oxidation methanol fuel cell. The Pt/Ni and Pt/Ru/Ni alloys showed excellent catalytic activities compared to those of pure Pt and Pt/Ru. The role of Ni as a catalytically enhancing agent in the oxidation process was interrogated using cyclic voltammetry, chronoamperometry, X-ray photoelectron spectroscopy, transmission electron microscopy, and X-ray diffraction. X-ray diffraction data showed alloy formation for all Pt/Ni, Pt/Ru/Ni, and Pt/Ru nanoparticles, whereas X-ray photoelectron spectroscopy confirmed that chemical states of Pt were exclusively metallic. The presence of metallic Ni, NiO, Ni(OH)2, NiOOH, metallic Ru, RuO2, and RuO3 was also confirmed. We found that the Pt4f binding energies for the Pt/Ni and Pt/Ru/Ni alloy nanoparticles were lower than those for clean Pt na...


Pursuant to Regulation 30 and 47 of the SEBI (Listing Obligations and Disclosure Requirements) Regulations, 2015, please find enclosed e-copies of newspaper advertisements published today Le., 19th February, 2021 regarding the Voting Results of the Meetings of the Equity Shareholders and Commercial Paper Holders of Britannia Industries Limited held on Monday, 15th February, 2021 at 11:00 AM and at 2:00P.M respectively, through Video Conferencing, pursuant to the Order of the Tribunal, dated 23'd December, 2020, as corrected by a Corrigendum dated 11th January, 2021 to the said Order, for the purpose ofconsidering, and if thought fit, approving, with or without modification(s), the Scheme of Arrangement amongst Britannia Industries Limited and its Members under Sections 230 to 232 and other applicable provisions of the Companies Act, 2013:


Sandia Nuclear Waste Management Program is pursuing for DOE an option for permanently disposing radioactive waste in deep geologic repositories. Included in the Program are the Waste Isolation Pilot Plant (WIPP) Project for US defense program mixed waste the Yucca Mountain Project (YMP) for spent power reactor fuel and vitrified high-level waste, projects for other waste types, and development efforts in environmental decision support technologies. WIPP and YMP are in the public arena, of a controversial nature, and provide significant management challenges. Both projects have large project teams, multiple organization participants, large budgets, long durations, are very complex, have a high degree of programmatic risk, and operate in an extremely regulated environment requiring legal defensibility. For environmental projects like these to succeed, SNL`s Program is utilizing nearly all areas in PMI`s Project Management Body of Knowledge (PMBOK) to manage along multiple project dimensions such as the physical sciences (e.g., geophysics and geochemistry; performance assessment; decision analysis) management sciences (controlling the triple constraint of performance, cost and schedule), and social sciences (belief systems; public participation; institutional politics). This discussion focuses primarily on communication challenges active on WIPP. How is the WIPP team meeting the challenges of managing communications?`` and ``How are you approaching similar challenges?`` will be questions for a dialog with the audience.


The authors describe an 18-compartment hybrid computer multiple model of the uptake and distribution of halothane. This model uses 88 equations and 124 parameter settings. Three submodels are incorporated into the basic model: 1) The mass transport of halothane is simulated on the digital portion of the hybrid computer. 2) A breath-by-breath pulmonary model with two compartments describes air pressure-flow relations in the airway system. 3) A beat-to-beat cardiovascular model with 15 compartments describes in detail blood pressure-flow relations. In addition, a baroreceptor-heart rate loop is included: an increase in arterial pressure causes a decrease in heart rate. The slope of the baroreceptor response is progressively decreased by halothane until at 2 per cent there is no response.The model of halothane uptake and distribution is separate from the blood and air pressure-flow models, but is, in effect, driven by them. Myocardial "contractility" (stroke volume) and certain regional vascular resistances can be affected by the concentration of halothane in one or any proportion of any combination of three compartments: arterial blood (arteriolar concentration), cerebral gray matter, or myocardial. In turn, these factors significantly affect the uptake and distribution of halothane.The responses to three steady-state concentrations, as well as to a step change in concentration from 0 to 2 per cent, were examined. Twenty-four outputs were recorded, including halothane concentrations in ten compartments; myocardial "contractility"; left and right ventricular and right atrial pressures; cardiac output; stroke volume, R–R interval; and blood flows in six regions. Two variables—alveolar concentration of halothane and arterial blood pressure—were recorded during a step change of 0 to 5 per cent.The model describes the appropriate steady-state and dynamic cardiovascular responses to halothane. It also demonstrates the complex interrelationships among cardiac output, regional blood flow distribution, and the uptake and distribution of halothane. During step changes in halothane concentration, most of the responses occur early, a phenomenon also seen in man and goats.Thus, the model is useful not only for representing organ and tissue halothane concentrations, but also for gaining new insights into cardiovascular alterations produced by rapidly changing concentrations of halothane and into the complex interactions between the circulation and the uptake and distribution of halothane.


A linear time-varying controller is developed for stable linear time-varying systems described by a standard controlled autoregressive moving average model. The controller is able to guarantee a stable closed-loop system and the minimum variance control for tracking a desired output trajectory even when the plant parameters are fast time-varying.


TGFα is hypothesized to be an endogenous regulator of lens fiber terminal differentiation. With immunofluorescence, TGFα was localized to differentiating cells in the lens epithelium and superficial fiber cell mass of the adult chicken. A similar pattern of localization was also noted when differentiating epithelial cells were cultured. Immunoneutralization of endogenous TGFα inhibited the accumulation of filensin, a unique intermediate filament protein subunit restricted to developing vertebrate lens fibers. ELISA assays quantified the effects of TGFα on filensin expression. Surprisingly, inhibition of the TGFα receptors' tyrosine kinase activity with nanomolar concentrations of PD153035 increased the accumulation of differentiated characteristics in the presence or absence of ligand. Morphologically, PD153035‐treated cells grew as aggregated masses and spread less well onto the substrate. Accompanying these morphologic changes was a complete inhibition of cell division. Post‐receptor signaling events were examined with cAMP assays and Western blotting. TGFα did not affect cAMP levels while isoproterenol, an additional mediator of lens cell differentiation, caused significant increases in cAMP levels. Activation of ERK2 via dual phosphorylation was noted in response to TGFα but not isoproterenol. PD153035 reduced, but did not eliminate, ERK2 phosphorylation in response to TGFα. Phosphorylation of the CREB transcription factor was also observed in response to TGFα or isoproterenol. These data indicate that endogenous ligands can influence the expression of differentiated characteristics in cultured chick lens cells. A focus of multiple signaling pathways affecting filensin expression is the CREB transcription factor. While increased ERK2 activation may be involved in stimulating cell division, lower levels of persistent ERK2 activation promotes differentiation thus indicating some form of signaling pathway compartmentalization. This could also mean that additional receptors for TGFα not inhibited by PD153035 are responsible for promoting differentiation in chick lens cells. J. Cell. Physiol. 186:288–297, 2001. © 2001 Wiley‐Liss, Inc.


Abstract Researchers investigating the incidental acquisition of vocabulary through reading must select either real or nonce words as targets. To determine whether this decision affects acquisition, English as a foreign language classes (English experimental n=80; nonce experimental n=89) were given a 2,381-token short story containing either 26 target English or nonce words. Analysis of the gain scores on an unexpected meaning recognition assessment for the two experimental and two control groups (English control n=73; nonce control n=114) found a statistically significant difference in acquisition. The large effect size found indicates the choice to use nonce targets has a clear effect on acquisition outcomes. Additional analysis also indicated the contextual richness of the words surrounding targets was subordinate to frequency of exposure in terms of encouraging incidental acquisition. Furthermore, learners' L2 vocabulary size had only a negligible effect on acquisition outcomes. Further analyses, implications, and consequences in regard to research practices are discussed.


The linear viscoelastic constitutive model,which in most popular FEM(finite element method) software,is unsuitable for solid propellant with large deformation.Based on the subroutine VUMAT(vectorized user defined material subroutine),a nonlinear viscoelastic constitutive model developed by Swanson was implemented into Abaqus.The constitutive model was coded using Fortran,and can be called as a subroutine.The validify of the subroutine had been proven through the standard uniaxial tensile model.The subroutine can be used for the analysis of large solid rocket motor.The shortage of Abaqus which only has linear viscoelastic constitutive model is remedied.Some useful technology,including the detail process of implementing a material constitutive model,was presented.It can be referred for extending the material constitutive model in Abaqus.


The disease in body and mind is the common and frequently occurring disease of university students in the new period.It is the obstacle for us to train the persons with high qualities.This article sets forth the reasons and countermeasures of the disease in body and mind for university students in the new period.It also involves the common disease in body and mind of university and the basic level of psychological health for university students.


The purpose of this study was to investigate the effects of Microcomputer Based Laboratory (MBL) on the middle school students` graphing skill and science process skill in Earth Science classes. MBL teaching materials for inquiry-based instructions were developed to teach five experimental topics related to the middle school `Earth Science.` Thirty three middles school students participated in this study, and the pre- and post-tests were conducted. Results indicated as follow: First, MBL classes were effective in developing the graphing skill of middle school students. They were efficient both in graph construction and graph interpretation, especially in data transformation. Second, MBL classes were effective in helping participants to use science process skills, especially, in the subordinate areas including formulating hypotheses, making operational definition, graphing, and interpreting data.


The analysis of the most frequently recommended medications is showed in the article. The results of the survey of dentists conducted at the Shupyk National Medical Academy of Postgraduate Education in collaboration with Ukrainian Dental Association on dental conferences in February-March 2015. The basic group of pharmaceutical drugs – nonsteroidal anti-inflammatory drugs, antibiotics, and medicines for local use were researched. The analysis presents the most commonly prescribed drugs by dentists during the period of first half-year 2015. The survey results demonstrated the necessity to better inform dentists about new drugs and their indications for the usage based on evidence-based medicine, contraindications, and side effects in order to achieve high clinical efficacy of the treatment.


Every company in the trucking industry is looking for factors that will assure it of a sustainable competitive advantage. But for most of the sources of competitive advantage (e.g. core competence, time compression, continuous improvement and partnership) companies must pay more attention to human factors. In fact, the barriers to adaptive capability are largely social not strategic. For the trucking industry the question of human resources is characterized by four distinct levels of resources, i.e. top management, operational management, front line employees, and sub-contractors. This paper's focus is specifically on the first, second, and third levels. In concluding his paper, the author writes that specific programs addressing training needs for drivers are well underway. Once these are in place, the industry will need to put research at a higher level and maybe start looking at such matters as driving simulators: their needs, functions, and applicability. On the management side, the industry must begin thinking the European way and start seriously working on the establishment of a Canadian Training Institute for Road Transport. In Europe most countries have a training Institute that deals specifically with the questions of training for road transport personnel. The tasks and objectives of this Institute could be to develop curriculum, standards of training and programs for senior managers. Possibly, it could also, maintain the integrity of the programs developed under the joint EIC/Industry IAS program for truck drivers. But most important, the mission statement of this Institute should be to focus on quality and productivity standards for human resources. For the covering abstract of the Conference, see IRRD Abstract No. 807771.


AIM:To detect Duchenne muscular dystrophy(DMD)genetic deletion/duplication from the peripheral blood and amniotic fluid in the patients of DMD/Becker muscular dystrophy(BMD)by using multiple ligation probe amplification(MLPA)and fluorescent in situ hybridization(FISH),and to analyze the predictive value of these two techniques in prenatal diagnosis of DMD/BMD.METHODS:Five patients and 15 of their female relatives from 3 DMD/BMD families were selected and MLPA analysis was conducted.Deletions/duplication regions were used as directions for producing FISH probes labeling from BAC clones,with the X chromosomal centromere probe as control.The results of MLPA and FISH in detecting DMD/BMD patients and carriers of the peripheral blood and amniotic fluid were compared.RESULTS:The MLPA and FISH results of peripheral blood were fully accordant.Discordant results were found in 2 out of 3 amniotic fluid samples,where the FISH results were certified correct with the follow up investigations.CONCLUSION:Both MLPA and FISH are correct in detecting DMD deletion/duplication from blood samples,while more accurate results would be given by combination of FISH test.


A universal fuzzy controller, which can adapt to different control objects, is proposed. Controller parameters, such as the quantifying factors and the scale factor, and fuzzy control rules are optimized by chaos method, which is a combination of global and partial chaos searching. The method is applied to control three different nonlinear plants. Simulation results show that the optimization method is efficient to search for controller parameters and control rules, and the control has the advantages of strong robustness and adaptability. The algorithm has a simple structure and is easy to realize. This universal fuzzy controller is better than the common one.


Strategic human resources planning is a process to determine human resource needs of a company to realize strategic goals. This process differs from human resource planning in terms of activity planning that does include not only quantitative human resource requirements for a specific time frame but also qualitative human resource requirements according to strategy of the company and internal and external analysis of market. In this regard, strategic human resource planning consists of seven steps that are summarized in following bold statements; defining human resource strategy based on the company's strategy, meeting human resource demands of the company consistent with its goals, and developing programs and policies according to human resource demands.


Abstract Verification and validation of the "ARKAS" code, using problems defined in the IWGFR Coordinated Research Programme (CRP) for the comparison of LMFBR Core Mechanics Codes, are discussed. The problems to be used in the verification (code against code) and validation (code against experiment) were defined and calculated by 11 core mechanics codes from 9 countries. The solutions obtained by these codes were compared in two steps, the first step consisting of Stage 1 "Verification", and the second step including Stage 1A "Advanced verification" and Stage 2 "Validation". The results of the first step for ARKAS, a core structural mechanics code, were presented and discussed in a previous paper. This paper describes some typical ARKAS results in detail, and compares them with the average values taken from solutions obtained by participants in the CRP. This corresponds to the second step; Stage 1A and Stage 2. All the problems have been completed and were solved using ARKAS. Predictions made by ARKAS agr...


The paper describes a novel system to alter and redirect sunlight under large roofs with the help of a liquid lens system. Focus lies on the computational design, testing, measurement and evaluation of the performance of a physical prototype. The results in terms of daylight and illumination of the interior, as well as the possibility for sunlight redirection, lead to an array of adaptive natural light spotlights, which are rather promising. The journal article is an extension of previously reported work[1].


Neighbourhoods are increasingly gaining attention as planning units of great potential for contribution to sustainable development. Many assessment tools such as LEED-ND, BREEAM Communities and CASBEE-UD have been developed to examine the sustainability of neighbourhood development projects. Some of these tools are claimed to be suitable for assessment in different contexts, and LEED-ND has already been utilised in various countries. This study investigates the viability of using global standards through a series of comparative case studies. One certified case from each of the aforementioned tools is chosen and evaluated against its non-corresponding assessment tools. Selected cases are, respectively, Hoyt Yards, MediaCityUK and Koshigaya Lake Town. Results of this study provide evidence that casts doubt on the viability of using global standards. The paper concludes that neighbourhood sustainability assessment should be regarded as a pluralistic practice. This implies that any realistic and reliable assessment should take account of the specificities of specific locations and varying needs of different stakeholders.


Waltz (1981) argued in The spread of nuclear weapons that 'more [nuclear weapons] may be better' for securing international order. This argument stands apart from the majority view that nuclear non...


Patent ductus arteriosus (PDA), defined as an arterial connection between the pulmonary artery and the aorta, is a common congenital cardiac defect. The connection can be closed surgically or by transcatheter methods. The overall incidence of PDA in infants born prematurely is about 16 times higher than that in full term infants. Preterm infants with symptomatic heart failure secondary to persistent PDA can be treated by surgical ligation or by conservative treatment involving indomethacin or ibuprofen. The latter, more conservative approach, is usually the treatment of choice due to the risks involved with surgical ligation in premature babies.1),2)

Transcatheter techniques for PDA closure have been evolving for over 40 years, and most PDAs can be safely closed in the laboratory setting using currently available coils and devices. Transcatheter closure of the ductus has been effective, with shorter hospital stay and lower cost compared to surgical closure.2),3)


Objective:To compare activation of two kinds of S9 which were induced by PCBs and the combination of PB and BF and to investigate effect of the difference of activation of two kinds of S9 on the test result.Methods:The number of revertant colonies of positive contrast group in the presence of different dose of S9 were compared in Ames assay respectively,and mutant frequency of positive control were compared in chromosome aberration,content of protein was determined by the method of Lowry,and content of P450 of two kinds of S9 were determined according to the method of Omura and Sato.Results:In the Ames assay,the number of revertant colonies had dose-response relationship among the dose of S9.When conditions such as strains and the dose of S9 were same,the number of revertant colonies in positive control was at the approximate level in presence of different S9 respectively.Mutant frequency between positive controls in the presence of different S9 had no significant difference in chromosome aberration.Content of protein S9 induced by PCBs was 13.3g·L~ -1 ,content of P450 was 3.92 nmol·mg~ -1 pro,content of protein of the other was 15.2 g·L~ -1 ,content of P450 was 2.94 nmol·mg~ -1 pro.Conclusion:Two kinds of S9 both show distinct activation in positive control in Ames assay and chromosome aberration.The activation of two kinds of S9 had no significant difference in related strains and positive contrast in Ames assay and chromosome aberration.The inducing method of combination of PB and BF can take the place of the inducing method of PCBs in the preparation of Liver homogenate S 9.


The invention provides a method for selective bromination of keton carbonyl compounds by using n-bromosuccinimide (NBS), which is characterized by dissolving a reaction substrate keton carbonyl compound in an ethanol or methanol solvent, adding thiourea, stirring for dissolution, adding NBS, and holding a reaction temperature at 20-80 DEG C for 20-30 min; and performing post-treatment on an alpha-bromination reaction product of the keton carbonyl compound. If the reaction product is solid, the post-treatment step comprises standing the reaction product, cooling, performing vacuum filtration, washing a filter cake with a reaction solvent, drying in vacuum to obtain a crude product, and recrystallizing with the reaction solvent; and if the reaction product is liquid, the post-treatment step comprises performing rotary evaporation on the reaction product, adding carbon tetrachloride, heating for dissolution, filtering off insoluble substances, performing rotary evaporation on the obtained filtrate to obtain a crude product, and separating and purifying the crude product by silica gel column chromatography.


In the next decades, Romania will experience demographic changes that are likely to have a significant impact on its economic development. Using an overlapping generations model in the Auerbach-Kotlikoff tradition, I attempt to assess the effects of the ageing population phenomenon. The driving force of the model is the population evolution which is imposed as exogenous and is based on projections from Eurostat. The study is not designed to provide precise forecasts but rather a set of economic trends which are likely to be induced by the demographic transition. Simulations covering the next 100 years were conducted under two alternative scenarios, depending on the method of balancing the social security budget. First, I assume the contribution rate adjusts in order to cover the growing financing needs. Second, the contribution rate is constant and the pension to wage ratio (and indirectly the pension) adjusts. The possibility of increasing the retirement age was also considered. The results confirm that the population ageing has a greater impact in the first scenario.


Electron-impact ionization cross sections for argon are calculated using both non-perturbative R-matrix with pseudo-states (RMPS) and perturbative distorted-wave methods. At twice the ionization potential, the 3p6 1S ground-term cross section from a distorted-wave calculation is found to be a factor of 4 above crossed-beams experimental measurements, while with the inclusion of term-dependent continuum effects in the distorted-wave method, the perturbative cross section still remains almost a factor of 2 above experiment. In the case of ionization from the metastable 3p54s 3P term, the distorted-wave ionization cross section is also higher than the experimental cross section. On the other hand, the ground-term cross section determined from a non-perturbative RMPS calculation that includes 27 LS spectroscopic terms and another 282 LS pseudo-state terms to represent the high Rydberg states, and the target continuum is found to be in excellent agreement with experimental measurements, while the RMPS result is below the experimental cross section for ionization from the metastable term. We conclude that both continuum term dependence and interchannel coupling effects, which are included in the RMPS method, are important for ionization from the ground term, and interchannel coupling is also significant for ionization from the metastable term.


Silver pollution in the marine environment is of concern, particularly, with the rapid increasing use of silver nanoparticles in consumer products providing additional sources of silver emissions. Silver is highly toxic and known to bioaccumulate in aquatic organisms; however, the risk silver poses to the marine ecosystem is poorly understood. The sperm whale (Physeter macrocephalus), a toothed whale having a wide global distribution and high trophic level, is a sentinel of ocean health. The aim of this study was to provide a global baseline for silver as a marine pollutant using the sperm whale as an indicator species. Skin biopsies were collected in free-ranging sperm whales around the globe during the voyage of the research vessel, Odyssey, during 2000 and 2005. Total silver levels were measured in 298 sperm whales from 16 regions. Detectable levels were found in 176 whales and ranged from 0.1 to 4,179.0 μg/g ww with a global mean level of 16.9 ± 14.1 μg/g ww. The highest mean level was found in whales sampled in waters near Seychelles with 123.3 μg/g ww, and the lowest mean in whales near Chagos with 0.1 μg/g ww. These data provide an important global baseline for silver pollution that precedes the recent emergence of silver nanoparticles.


10014Background: Epigenetic regulation via methylation plays a crucial role for the functioning and survival of neuronal cells. DNA methyltransferase 1 (DNMT1) is an enzyme to maintain methylation ...


SUMMARY This paper presents a third, subsequent, experiment to assess the performance of various visual variables for better visualization of 3D cad astre models. The case study is a 3D spatial representation of an apartment building with co-own ership units. The third experiment focuses on the following hypotheses "Transparency i s performing to distinguish two groups of bounding objects such as physical (e.g., walls) and legal (administrative units) and to give the impression of ownership". These objects are dis tinct and essential for use by notaries, one category of user of 3D cadastre models, since the s patial relationships between them may directly influence the determination of ownership, and the associated rights and responsibilities. The methodology is based on onlin e questionnaire showing twelve 3D models where participants are invited to test their ability to decide if the wall of a specific apartment belonged to them or not. For data analysi s, groups of participants are categorized according to being skilled in cadastral data manipu lation, and in 3D data visualization. This paper presents preliminary results of those tests.


The adjustment and updating of industrial structure is bound to the optimization of industrial organization structure and technology innovation.The priority is given to the subsidization of hi-tech and new service industries,development of mainstay industry,reconstruction of traditional industry,gradually setting up a capital and technology intensified and highly industrial related modern economy.The paper maintains that the economic background should be studied before the practical adjustment is conducted so as to determine a proper direction,pattern and approach for adjustment and updating.In this way,the comprehensive industry competitiveness can be enhanced while established industry system can be compatible with population growth,resources reservation and environment as well.


The urban park is part of urban biodiversity that restore the diverse ecosystem to be resilient from rapid urbanisation impact. Also, it is an invented landscape that serves recreational opportunities as well as contemplation. However, significant evidence to measure the contemplativeness of Malaysian urban parks as an eco-psychological restoration resource is indistinct. Previously, the restorative environments have determined by personal opinions and evaluations of researchers without operationalising the empirical study on landscape design quality. This study evaluated Taman Tasik Shah Alam's contemplativeness via expert evaluation assessed by ten Malaysian Landscape Architects. The assessment involves eight physical attributes using Contemplative Landscape Model criteria on 35 images via an online survey. Eventually, five of the most contemplative scenes are recognised as eco-psychological restoration resources to remedy psychological distress, including landscape composition types. It also highlights the necessary physical attributes of the urban park towards inventing the existing one into a contemplative environment for the betterment of communities. Thus, the contemplative landscape can serve as an antidote for people affected by psychological distress to contemplate themselves by exposing and experiencing well-preserved urban biodiversity.


This paper was compiled from various first-hand documents obtained mainly from the Prime Ministry Ottoman Archives, the National Archives, the British Newspaper Archives and the classical works and written works obtained from some research centers. These documents, which involve * Yrd. Doç. Dr., Dicle Üniversitesi, Edebiyat Fakültesi, Tarih Bölümü, email@example.com. XIX. Yüzyılda Fırat ve Dicle Havzasında Büyük Güçlerin Nüfuz Mücadeleleri 31 significant information, made significant contributions for the completion of this study. Since the topic about which we tried to give detailed information is concerned with the great powers' conflict on the Euphrates and Tigris region, we specifically concentrated on this subject and were satisfied with giving general information about both the Middle East and Iraq. Inarguably, the winner of this conflict on that area in the beginning of the 19 th century was the British Empire. Nevertheless, this accomplishment was not an easy one for the British Empire. They gained this triumph by virtue of defeating French, Russians, Dutch, and German forces after a long-standing struggle. In this study, we aimed to present details about the conflict between the Great Powers on that region and the British Empire's success against the others.


The results of morphophysiological parameters studies carried out in 2008-2010 for Marsh frog populations in the Ufa urban areas are presented. It is found that in the habitats with critical anthropogenic transformation in comparison with the control zone can be observed both increase of relativistic mass: testis (P


The paper researches the current indirect sports behaviors of the disadvantaged groups in the urban com munities of the Shanxi province and points out that there is a great gap between the disadvantaged groups and the or dinary urban residents in their indirect sports behaviors.The paper proposes to develop diversified community ser vice with multiple levels,improve the training of the staff of the community sports service,improve the community sports service facility network and improve the community sports service mechanism.


This paper analyzes the evaluation index of the harmonious development between social economic growth and information industry, then based on the characteristics of DEA method and AHP method and combining these two methods, it set up an DEAHP model with AHP restraint to evaluate the harmonious development process and proposes a new concept, named state harmony degree, and a series of formulas to measure the harmonious development between social economic system and information industry.


The lipid soluble constituents of fibrous roots and tubers of Ophiopogon japonicus were compared by using GC-MS.Sixty one peaks were detected in fibrous roots of O.japonicus and 42 peaks in tubers of O.japonicus,respectively.Additionally,36 compounds were identified and confirmed by analysis of MS spectra and indexing of NIST 98 spectral database.Twenty nine compounds were found from the plant for the first time.The present paper provided valuable experimental data for further studies on chemical constituents of O.japonicus and exploration of fibrous roots of O.japonicus.


The dangers implicit in the present situation [Government micro-management of universities] lie in the emergence of a compliant rather than a dynamic system, in the unconscious self-framing of the development of legally independent and autonomous institutions of learning in an inappropriate public service model, and the tacit acceptance of limitations on institutional freedoms that have imperceptible impacts on the quality of intellectual life; it will over time stifle institutional innovation. The invisible, and perhaps the not so invisible, hand that guides policy will not be the market as some commentators fear but the hand of Government and of a centralised bureaucracy which regards the direction of higher education simply as part of a larger set of questions as to the affordability of public service provision.


Through the pyrogenation experiments on fresh coal samples carried out by procedural heating-up testing equipment,the concentration of oxygen,carbon monoxide,carbon dioxide and other hydrocarbon were tested,and the properties of these gases with the change of temperature were studied.The index gases to predict coal spontaneous combustion were studied and the conclusion was reached that taking carbon monoxide as the main index gas,and ethylene and the ratio of ethylene and ethane as the auxiliary index gases.Based on the study,thermocouple probes were used to monitor the temperature of coal in 7312-2 goaf which was effective and precise to reflect the tendency of coal in goaf.The study has important significance in improving the accuracy of forecasting and predicting of early coal spontaneous combustion and preventing the coal mine fire.


We compute the gravitational Chern-Simons terms induced by several vector models in D = 3. We also comment on the possible applications to the Bose-Fermi correspondence.


Supervised classification on remotely sensed data is a classical method to detect objects automatically and to update topo-graphical datasets. To train the classifier, already labeled image data are needed. The training labels are typically created manually for parts of the given data, which is time-consuming and thus costly. Another approach would be to use the labels from an old and outdated dataset, called map, to avoid manual effort. Due to changes over time some of the labels might be wrong, and thus the used classifier has to be able to deal with that. In this paper, we apply label noise robust classification on two hyperspectral datasets using a simulated outdated map for training.


Abstract PBT sheets were extruded from T-die using a single extruder and were winded by a take-up roller controlled at 50°C and with speed at 1.2 m/min. Oriented PBT sheets were prepared with various winding roll speeds at 3.6, 4.8 and 6.0 m/min. Fine structure and physical properties of PBT sheets thus obtained were investigated by measuring the molecular orientation, crystal structure, dynamic visco-elasticity, thermal and mechanical properties, sonic modulus, etc. PBT melts were found to be readily crystallizable in the sheet. In the case of roll drawing, the DRmax of PBT sheet was 5. The PBT sheets prepared from winding speed at 6 m/min showed polymorphism of both α- and β-form crystallites with crystallinity of about 24%. In the tri-directional WAXD patterns, the PBT sheets by the roll drawing method turned out to be oriented in the uniplanar-axial form. For the roll drawn PBT sheets with various winding speeds, large orientation effects were observed in the winding direction together with improved thermal and mechanical properties.


Under some circumstances, a probabilistic reasoner who encounters a sequence of observations will change his estimate of the likelihood of a proposition φ from very low to very high and back again many times. However, the prior probability of such a sequence of observations is necessarily very small. We compute an exact value of the maximal value of this probability, as a function of the amount of change and the number of changes. The calculation does not involve any independence assumptions over the observations.


The influence of the relation of maximum aggregate size and the size of concrete specimen on compression strength has been analyzed. The wall-effect as a parameter which represents this influence is reaffirmed.
Two large series, of the pairs of 15 cm and 20 cm cubes made from the same concrete sample, were tested in compression. For each series and each cube size, average compression strength and standard deviation have been determined. The registered effects are discussed, considering theory of the weakest link and the wall-effect.
For a given maximum size of aggregate, minimum size of concrete specimen is proposed.


There are many factors that cause accidents while driving a car. Among them, one factor is a negative emotional state such as "anger", "frustration", or "irritation" [1]. To detect these negative emotional states, the are several studies and commercial driving systems that have been presented as the driver monitoring system (DMS). These approaches, that mainly depend on image processing and natural language analysis uses the information that expressed information that could be arbitrarily changed. Alternatively, the emotional analysis method using physiological responses that would not be arbitrarily changed and is objective. In this study, we propose the way of estimating emotion named the Bio-emotion Estimate Method (BeEM) that can identify emotions by applying the brain waves and heart rate estimated using Russell's circular model. We developed a driving simulator that performs emotional analysis and analyzed emotional reactions to multiple incidents using values estimated from this biological information. Then evaluate and compare with the BeEM and iiSA which is a emotion judgment indicator used during driving. The result shows that similar tendency has found in the proposed method and those obtained by the existing emotion evaluation method, suggesting the applicability to DMS of using biological emotion information.


Abstract Fish yield and gross photosynthesis were highly correlated in six ecosystems. Gross photosynthesis of phytoplankton and attached plants was measured as diel oxygen changes in unconfined water. Fish yield was measured by capture of all fish at the end of the experiments. Fish yield as live weight ranged from 0.54 to 2.48% of gross photosynthesis. The range of percentages was attributed to differences in foods used and to differences in stocking densities. Species of fish were rainbow trout (Salmo gairdneri), channel catfish (Ictalurus punctatus), goldfish (Carassius auratus), and tilapia hybrids (Tilapia mossambica x Tilapia hornorum).


The present invention discloses a method of real-time information broadcasting in web belongs to internet on-line communication field. Web browsers input information into server through web page, then the information is transferred in a pushing form by the server to all the client browsers contacting with the server, then a mechanism that users inputted information being real-time broadcasting and receiving is implemented. Through the mechanism any user inputted on the web can be real-time received and displayed by other web browsers. Because most web browsers on the internet support flash player plug-in, and the method need client browsers support the plug-in and web client has no need to install any other plug-in, which is utmost convenient for users using and development & deployment for developers. The technical scheme used in the invention is invoking flash sending control to send information and invoking flash receiving control to receive real-time information transferred from a remote end server so as to implement mechanism of real-time information broadcasting in web.


Improvement ofN fertilizer recovery efficiency (NRE) is necessary to reduce excess N entering the environment and to increase economic returns. A 2-yr field trial was established in 2005 in Northeast Missouri to determine the effects of conventional and slow-release N fertilizer sources and landscape position (summit, sideslope, and low-lying) on crop growth and NRE in corn (Zea mays L.) in a claypan soil. Nitrogen fertilizer treatments at 168 kg N ha ―1 consisted of pre-plant applied and incorporated polymer-coated urea (PCU), urea, 50% PCU/50% urea mix by weight, anhydrous ammonia (AA), and a nontreated control. Gravimetric soil water content data in 2005 and 2006 indicated that the low-lying position was often wetter than the summit and sideslope positions. Anhydrous ammonia and PCU treatments increased grain yield 1470 to 1810 kg ha ―1 over urea in the low-lying position in 2005 and 2006. Corresponding increases in plant N uptake and NRE were observed in the low-lying position in 2005 with use of PCU and AA compared to urea, but not in 2006. Based on the grain yield results in this research and different fertilizer cost and crop prices, gross profit differences for use of PCU and preplant-applied AA compared with urea in the low-lying position could range from $50 to $642 ha ―1 . These results demonstrate that targeted use of different N fertilizer sources in claypan landscapes may increase grain yields and profitability.


The aim of this study was to identify the different motivational profiles shown by a sample of 699 students of Physical Education compared with the importance they granted to this subject. For that aim, they were administered instruments measuring sport motivation, motivational climate, psychological mediators and the importance granted to physical education. A cluster analysis yielded three profiles: The first profile was named 'self-determined profile' because students showed a high self-determined motivation; the second profile was named 'non self-determined profile' as students showed low levels of intrinsic and extrinsic motivation; finally, the third profile was coined 'moderate motivation profile" because subjects showed intermediate intrinsic and extrinsic motivation and high demotivation. Students with self-determined profile were at the same time those who granted higher importance to physical education.


The pharmacokinetics (PK) of hetrombopag were found to be nonlinear across evaluated dose ranges. The aim of this study was to develop a mechanism‐based population pharmacokinetic/pharmacodynamic (PopPK/PD) model and to provide a reasonable expected therapeutic dose for a future confirmatory clinical study of hetrombopag.


The flow processing of the melts of automotive plastic bumper in the injection molding was simulated by means of Moldflow software. The filling time, pressure of v/p swich-over,clamp force, residual stress and welding lines distrubution of two programs were analyzed by setting six gates and three gates. According to the results of simulation, the efficiency of three gates was better than that of six gates.


This article considers the dynamics of the natural population growth (E) indicators of Kuldiga Region over the past 28 years and gives a geo-ecological analysis of the favourability of the Kuldiga Region territory for its inhabitants, based on four environmental factors. This article specifies that E value in Kuldiga Region is higher than E values in Vidzeme and Latgale territory, but it is the lowest in Kurzeme regions. In order to find out the reasons for this phenomenon, such environmental factors have been analysed in the article as intensity and horizontal gradients of the anomalous magnetic and gravitational fields.


New isolation of (1R,2S,5R)-(−)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexan-1-ol ((−)-8-phenylmenthol, I), prepared from (R)-(+)-pulegone, is described. The method consists in the preparation of phenylcarbamate of I and its transesterification with ethanol. Further two diastereoisomers of (−)-8-phenylmenthol were isolated: the (1S,2R,5R)-isomer II and the (1R,2R,5R)-isomer III. Compounds I, II and III were converted into their respective glyoxylates


ProlactinstimulatestheexpressionofmilkgenesduringlactationthroughtheactivationofSTAT5transcriptionfactors,which subsequently bind to their cognate target sequence on the promoters. Demethylation of 5methylCpG dinucleotides permits the tissue-specific accessibility of transcription factor-binding sites during development, but remethylation has not been showntocontributetoacutesuppressionofgeneexpression.WecharacterizefunctionallyanovelSTAT5-bindinglactational enhancer in the far upstream promoter (wK10 kbp) of the bovine aS1-casein-encoding gene. This promoter area is hypomethylatedinthelactatingudder only.Remethylationofthisareaaccompaniesanexperimentallyelicitedacuteshutdownof casein synthesis in fully lactating cows, whose udder quarters have experimentally been infected with a pathogenic E. coli strain. Within 24 h after infection, the relevant promoter area was remethylated from 10% of the DNA molecules in the uninfected control quarters to w50% in the infected quarters, the typical values for fully lactating and not lactating udders respectively. Increased methylation resulted in tighter chromatin packing. Concomitantly, the aS1-casein mRNA concentration dropped to w50% while the protein synthesis was shut down to w2.5% in the infected quarters, alone. The


We investigate sequential derivation languages associated with graph grammars, as a loose generalisation of free-labeled Petri nets and Szilard languages. The grammars are used to output strings of rule labels, and the applicability of a special rule determines the acceptance of a preceding derivation. Due to the great power of such grammars, this family of languages is quite large and endowed with many closure properties. All derivation languages are decidable in nondeterministic polynomial time and space O(n log n), by simulation of the graph grammar on a Turing machine.


TWODANT (Two-Dimensional, Diffusion-Accelerated, Neutral-Particle Transport) code has been benchmarked against 6 critical experiments (Jezebel plutonium critical assembly) and their k effective values compared with those of KENO and MCNP codes.


This article could be called "theme and variations" on Cantor's celebrated diagonal argument. Given a square nxn tableau T=(a_i^j) on a finite alphabet A, let L be the set of its row-words. The permanent Perm(T) is the set of words a_{\pi(1)}^1 a_{\pi(2)}^2 ...a_{\pi(n)}^n, where \pi runs through the set of permutations of n elements. Cantorian tableaux are those for which Perm(T)\cap L=\emptyset. Let s=s(n) be the cardinality of A. We show in particular that for large n, if s(n) (1+\epsilon) n/log n then most of the tableaux are Cantorian. We conclude our article by the study of infinite tableaux. Consider for example the infinite tableaux whose rows are the binary expansions of the real algebraic numbers in the unit interval. We show that the permanent of this tableau contains exactly the set of binary expansions of all the transcendental numbers in the unit interval.


The introduction of imatinib, a specific inhibitor of the Bcr-Abl tyrosine kinase, has dramatically changed the management of chronic myeloid leukemia (CML). More than 10,000 patients worldwide have been treated with imatinib in clinical trials, and a large body of information has accumulated about the use of this drug. The purpose of this article is to review practical guidelines in regard to optimal dosing, monitoring, managing common side effects such as myelosuppression, and potential drug interactions. The treatment recommendations are intended to optimize therapy with imatinib while taking into account a patient's specific circumstances. J Clin Oncol 21:1637-1647. © 2003 by American Society of Clinical Oncology. IMATINIB MESYLATE (Gleevec, Glivec [Novartis, Basel, Switzerland], formerly STI571) is a small molecule signal transduction inhibitor that specifically targets a limited set of protein tyrosine kinases—Abl, Arg (Abl-related gene), KIT, platelet-derived growth factor receptor (PDGF-R)—and their oncogenic forms, most notably Bcr-Abl. Imatinib represents the archetype of a new class of anticancer agents, small molecules with high selectivity toward a specific molecular target that is known to be responsible for the establishment and maintenance of the malignant phenotype. In chronic myeloid leukemia (CML), the efficacy of imatinib is unprecedented, with rates of complete hematologic response (CHR) approaching 100% in patients in the chronic phase. Although therapy with imatinib is generally well tolerated, it is not devoid of side effects. Particularly common side effects include myelosuppression, nausea, edema, fatigue, headaches, muscle cramps, arthralgias, myalgias, diarrhea, and skin rashes. Patients were rapidly accrued onto a series of clinical trials (closely monitored phase I and II protocols and "expanded access" protocols with less stringent documentation requirements). Only 3 years passed between the enrollment of the first CML patient in the phase I protocol and approval by the Food and Drug Administration (FDA) of imatinib for the treatment of patients with CML in advanced phase or after failing interferon alfa (IFN) therapy. Results recently have become available from a phase III trial that shows imatinib to be vastly superior to IFNplus cytarabine in newly diagnosed patients in regard to hematologic response, cytogenetic response, and time to progression to accelerated phase or blast crisis. These data have led to FDA approval of imatinib for treatment of patients with newly


ECOG 1696 was a Phase II multi‐center trial testing vaccination with melanoma peptides, gp100, MART‐1 and tyrosinase delivered alone, with GM‐CSF, IFN‐α2b or both cytokines to HLA‐A2+ patients with metastatic melanoma. Here, the frequency of circulating CD8+tetramer+ (tet+) T cells and maturation stages of responding T cells were serially monitored and compared with baseline values in a subset of patients (n = 37) from this trial. Multiparameter flow cytometry was used to measure the frequency of CD8+ T cells specific for gp100, MART‐1, tyrosinase and influenza (FLU) peptides. Expression of CD45RA/CCR7 on CD8+tet+ T cells and CD25, CD27, CD28 on all circulating T cells was determined. Vaccine‐induced changes in the CD8+tet+ T cell frequency and phenotype were compared with results of IFN‐γ ELISPOT assays and with clinical responses. The frequency of CD8+tet+ T cells in the circulation was increased for the melanoma peptides (p < 0.03–0.0001) but not for FLU (p < 0.9). Only gp100‐ and MART‐1‐specific T cells differentiated to CD45RA+CCR7‐ effector/memory T cells. In contrast to the IFN‐γ ELISPOT frequency, previously correlated with overall survival (Kirkwood et al., Clin Cancer Res 2009;15:1443‐51), neither the frequency nor differentiation stage of CD8+tet+ T cells correlated with clinical responses. Delivery of GM‐CSF and/or IFN‐α2b had no effects on the frequency or differentiation of CD8+tet+, CD8+ or CD4+ T cells. Phenotypic analyses of CD8+tet+ T cells did not correlate with clinical responses to the vaccine, indicating that functional assessments of peptide‐specific T cells are preferable for monitoring of anti‐tumor vaccines.


The strongest attribute in nurse's life would be to possess an attractive personality. The 21st century nurses need to focus and capacity build on their personalities to enable them survive, adapt, and thrive in this fastchanging world. Capacity Building on personality would mean to develop and strengthen the skills, instincts, abilities, processes and resources of nurses which makes them more competent and productive ensuring quality nursing care. Hence, the health and family welfare department of Tamilnadu has conducted a study to assess the effectiveness of a workshop in 5 phases on capacity building of nursing superintendents in the state of Tamil Nadu with the aim of assisting them to fine tune their leadership skills, decision making, conflict management and team building skills.


Multiple procedures are used to detect the presence of second mesiobuccal canal in the mesial root of the upper first molar. In this article, a case will be presented in order to show the use of cone-beam computed tomography (CBCT) in the detection of asecond mesiobuccal (MB2) canal in maxillary first molar, unidentified neither clinically nor with conventional radiographic methods.


There are two orders of facts about polysemy: a satisfactory theory must account in a natural way for both. The first concerns differences in the semantic content of the interpretations of a word in different contexts. It is this aspect of polysemy which has been the most actively researched, with the aim of discovering regularity and predictability. Noteworthy recent proposals concerning polysemy have emerged from two main sources: firstly, from cognitive linguists such as Lakoff and Taylor; secondly, from computational linguists, most notably Pustejovsky.


The article analyzes the possibilities of modern high-tech techniques of reflexology stimulation of acupuncture points based electromagnetic millimeter wave and submillimetrovogo ranges of stimuli an ultra-low intensity in medical rehabilitations, according to the literature and results of own clinical and experimental research.


Description Researchers plan to study organic-rich rocks in terrestrial labs, looking for past life Researchers plan to study organic-rich rocks in terrestrial labs, looking for past life


Cadmium Zinc Telluride (CdZnTe/CZT) crystals were grown using a modified vertical Bridgman growth technique with 10 % Zn concentration at Washington State University (WSU). Analyses of the effects of volume (vol.) %, number density (cm-3), mean diameter (μm) of secondary phases (SPs) and thickness (mm) of the CZT crystals on single crystal properties such as carrier mobility lifetime (μτe) and resistivity (ρ) were performed. Some correlations were observed between μτe values of different CZT crystals and vol. %, number density, mean diameter of SPs and thickness of the crystals. High μτe and lower SP vol. % values were obtained for the ingots grown with rapid cool down times and with no intentional amounts of excess Te/Cd. For the selected samples, the effects of the SPs on the μτe values were established for the SPs whose mean diameters were ≤4 μm and >4 μm. These studies indicate vol. % and mean diameter of SPs are the important parameters for CZT crystal performance as a radiation detector.


The ZINC database of commercially available compounds contains biologically relevant representations of purchasable compounds in ready‐to‐screen formats. ZINC uses catalogs from over 50 compound vendors, changing from time to time to reflect newly available compounds and depleted stock. ZINC is available in subsets that reflect current opinion in the field such as "fragment‐like" and "lead‐like," and has a facility to create additional small ad hoc subsets. ZINC has a search facility, as well as a service to process molecules that are not in ZINC by uploading them to a server. Curr. Protoc. Bioinform. 22:14.6.1–14.6.23. © 2008 by John Wiley & Sons, Inc.


The mechanism of postoperative hypochloremia has now found some explanation, since Legue showed that chlorine is selectively fixed in the area of tissues damaged by the operation. The authors examined a dog's kidney through which Ringer-Locke fluid was passed.


In this paper, we present results about the existence and uniqueness of solutions of elliptic equations with transmission and Wentzell boundary conditions. We provide Schauder estimates and existence results in Holder spaces. As an application, we develop an existence theory for small-amplitude two-dimensional traveling waves in an air-water system with surface tension. The water region is assumed to be irrotational and of finite depth, and we permit a general distribution of vorticity in the atmosphere.


Design of a Ka-band low loss circularly polarized omni-directional slot array antenna is presented. The slot array is conformal on a circular waveguide and the slots are radiating into a parallel plate region for circular polarization. Elevation beam is directed to +10 degrees for the required elevation coverage of -10°/+30°. Simulation results show that the return loss is better than 20 dB in 1% bandwidth. Gain of the antenna greater than 1 dBi and the axial ratio better than 4.2 dB in the full sector of coverage.


Oral follow‐up therapy is problematic in moulds with reduced azole‐susceptibility, such as azole‐resistant Aspergillus fumigatus infection. Currently, only intravenous liposomal amphotericin B (L‐AmB) is advocated by guidelines for the treatment of azole‐resistant aspergillosis infections. Preclinical research indicates that high‐dose posaconazole (HD‐POS) might be a feasible option provided that high drug exposure (ie POS serum through levels >3 mg/L) can be achieved and is safe.


The shipping industry plays an essential role in world trade. For shipping companies, having an accurate view of the markets and grasp of the interactions between the freight market, second-hand ship market, and the newbuild ship markets is essential. The shipping market cycles are divided into four periods (trough, recovery, peak, and recession) based upon shipping cycle theory. The current shipping markets have been stuck in the trough period since the financial crisis in 2008. This paper investigates the recovery period and causality relationship between the freight rate, second-hand price, and new-build ship price, in the dry bulk shipping market and applies the Granger causality test at each stage of the cycle based on quantitative analysis. The results show that the recovery period and causality relationship can be identified only during the trough and peak periods. When comparing the results for the trough period before and after the financial crisis, we find similarities between the two periods, leading us to conclude that the shipping cycle rules still apply.


Objective:To observe the effect of nape-aligned acupuncture on cerebral infarction patients with deglutation obstacle for brainstem auditory evoked potential,and to investigate the mechanism of nape-aligned acupuncture treatment.Methods:Eighty cerebral infarction patients with deglutation were selected and randomly allocated to nape-aligned acupuncture treatment group and control group.The control group received routine treatment,nape-aligned acupuncture treatment group added nape cluster acupuncture(fengchi acupoint,tianzhu acupoint,wangu acupoint,lianquan acupoint,panglianquan acupoint,jijin acupoint,yuye acupoint,fengchi acupoint,tianzhu acupoint and wangu acupoint needling,adam's apple direction,remaining 30 minutes,lianquan acupoint,panglianquan acupoint,root of the tongue direction,inhalaned 2 cun,Jinjin acupoint and yuye acupoint for insertion and blood letting,once for 3 days) in addition to the treatment for control group.Results:The total effective rate of nape-aligned acupuncture treatment group was 85%,and the total effective rate of control group was 77.5%.Excellence ratio of nape-aligned acupuncture treatment group was 70%,and control group was 35%,The difference before and after the therapy was notable(P0.05).Conclusion:Nape-aligned acupuncture treatment can regulate the BAEP(brain-stem auditory evoked potential) of cerebral infarction,increase the RCBF of the cerebral infarction patients,improve the condition of cerebral ischemia.Therefore,the conclusion is that one of the mechanism of action of nape-aligned acupuncture treatment is to cure the deglutation obstacle of cerebral infarction patients.


Two papers in this month's issue of the Journal report the application of advanced 'speckle tracking' techniques in the assessment of fetal cardiac function1,2. Even experienced practitioners in the field of fetal cardiology may lack familiarity with the techniques described. Most will be more used to methods that interrogate the blood pool, such as pulsed, continuous wave and color flow Doppler, or assessment of endocardial border motion by M-mode echocardiography. None of these techniques, however, measures deformation of the myocardium itself. Echocardiographic interrogation of myocardial motion has advanced dramatically due to newer imaging modalities, notably tissue Doppler and speckle tracking, coupled with computerized postprocessing. With regard to tissue Doppler, normal fetal values have been reported for both pulsed wave and color encoded techniques3–6. However, tissue Doppler techniques are significantly limited in that they are one-dimensional and highly dependent on the angle of insonation. Given that fetal lie is unpredictable, angle dependency remains a significant limitation. This is one reason why such techniques are restricted largely to research, with the possible exception of measuring time intervals in the assessment of fetal arrhythmias7,8. The use of speckle tracking for the assessment of fetal myocardial velocity and deformation is reported in this issue. Speckle tracking depends on the automated identification of unique patterns of ultrasound speckle patterns, often termed 'kernels', which can be tracked by the ultrasound system through the cardiac cycle9. Thus, myocardial deformation (strain), the rate of deformation (strain rate), and the velocity and vector of motion can be measured. Major attractions of this technique for the fetal heart are its lack of angle dependence, rapidity of acquisition (because it analyzes conventional grayscale images) and relatively rapid analysis. Furthermore, speckle tracking can assess regional as well as global myocardial velocities and deformation. Both papers1,2 report a decrease in right-ventricular (RV) peak systolic longitudinal strain with advancing gestational age, which is matched by a fall in RV longitudinal strain rate. Willruth et al.2 report a gestational age-related increase in global RV myocardial longitudinal peak systolic velocity, with higher velocities recorded at the base of the heart compared with at the apex, consistent with postnatal data. The fact that the analysis technique utilizes conventional gray-scale imaging, which is familiar and readily acquired, represents a major advantage over other techniques. Both papers confirm that the application of speckle tracking to the fetus is feasible but has a number of challenges. During intrauterine life, the fetal electrocardiogram (ECG) cannot be recorded easily so either mechanical events2 or dummy ECG signals1 are required to determine specific points, such as end-diastole, in the cardiac cycle. The frame rates achieved by crosssectional ECG are also of paramount importance and impact directly on results, particularly with respect to myocardial velocity, diastolic filling patterns and strain rate1. This is exemplified by comparison of high frame rate and low frame rate images1. Other limitations of the speckle tracking technique include the much lower frame rate compared with tissue Doppler imaging and the fact that, for most ultrasound systems, only speckles which remain within the imaging plane can be tracked; speckles which pass through the plane of insonation during the cardiac cycle are not included. Some 3D echocardiography systems now provide the means with which to track speckles through the plane via acquisition of a 3D volumetric dataset10,11, but there are currently no published data from the fetus using this technique. Perhaps one of the most important differences between speckle tracking techniques and more 'traditional' forms of analysis, such as M-mode or Doppler, is the extent to which the newer techniques are dependent on computer analysis. Using M-mode as an example, the operator dictates the image points and the formulae used to derive results, which themselves are not conceptually complex. In contrast, speckle tracking is more of a 'black box' and the user may not be aware of the precise impact of factors such as computational differences (natural versus Lagrangian strain) or the spatial and temporal resolution of the technique1. Recent work in children has demonstrated the impact of the use of different proprietary software on restudy of the same patient with respect to deformation imaging12,13. This limits the ease of comparison of results between and within centers. A key question when applying such techniques is the potential impact on assessment and management of fetuses. In their Discussion, Willruth et al.2 appropriately differentiate between fetuses who may have global cardiac dysfunction related to systemic disease and those with regional cardiac disease, for example aortic valve or pulmonary valve obstruction. This may be particularly important in the context of fetal intervention, providing new insights into the response to such interventions and aiding prognostication. However, isolated valvar obstruction is rare and likely to be studied on a multicenter basis, emphasizing the importance of methodology in


It is the only natural process through which the organic world obtains the reserve of free energy and which provides all bio-organisms with chemical energy. From the moment photosynthesis was discovered by Priestly, the researches passed several important stages. Further development of biophysicochemical aspects of synthesis till now resulted in its modern model and clarified the way of carbon during photosynthesis, concept of two photosystems, structure of reaction center etc.


The College of New Jersey and the University of Missouri are collaborating on a NSF Course, Curriculum, and Laboratory Improvement proof-of-concept grant to develop educational software for use in thermodynamics, fluid mechanics, and thermal systems courses. The THERMOVIEW software is being designed within the LabVIEW programming environment. It is hoped that by making use of the visual environment of THERMOVIEW and LabVIEW that students will gain greater insights into the processes involved and the flavor, if not the actual feel, of how systems behave in the real world. The purpose of this paper and presentation will be to provide an overview of the project to date and a description of current evaluation results.


Objectives 1) To assess performance and comfort level with cardiopulmonary resuscitation (CPR), foreign body removal (FBR), and seizure management in foster parents of medically fragile children; 2) To determine if the parents' performance and comfort levels increase with an individual teaching session with a medical professional to review CPR and FBR. Methods In this single cohort pilot study, 18 foster parents of medically fragile children were asked to rate their comfort level with pediatric CPR and FBR on a 5-point scale (1 = very uncomfortable, 5 = very comfortable). They then underwent five mock code scenarios and were evaluated using a 5-point scale (1 = poor performance, 5 = outstanding performance). A 6-month follow-up evaluation using similar scenarios was conducted. Results At visit 1, the percentage of parents demonstrating adequate performance of CPR, FBR, and seizure management was: 1) CPR: infant (78%); child (78%); 2) Foreign body removal: age <1 year (17%); age >1 year (65%); 3) Seizures (94%). At visit 2, performance improved in all areas, especially FBR, where the percentage of parents demonstrating adequate performance increased to 71% for children <1 year and 82% for children >1 year. As measured by the 5-point scales, CPR and FBR performance and parent comfort level with CPR improved significantly (Wilcoxon signed-ranks test,P< 0.004), but parent comfort level with FBR did not (P= 0.12). Conclusions Based on this pilot study, foster parents of medically fragile children benefit from an individual teaching session by a medical professional. CPR instruction for this group of foster parents should include adequate review and assessment of foreign body removal procedures.


This paper attempts to shed light on Saudi college students' internal motivational set up and how it negatively impacts their learning outcomes at the tertiary level at King Khalid University. To investigate that, a questionnaire that consists of ten questions was conducted on 90 (ninety) students selected from level four and eight in the Department of English of the same university. The responses of the learners indicate that the majority of the respondents are not highly motivated and chose English as a major- for their B.A. course- against their will as there were no other alternatives for several reasons. The results show- not surprisingly though- that most of the students are driven by extrinsic motivation to study English in order to get good jobs. The statistics obtained from the Department, of deprived and withdrawn students are quite high and that confirm the researchers' hypothesis of students' demotivation in the Department of English. Finally, researchers have suggested some remedial academic initiatives to help these undergraduate Saudi students in the Department of English at King Khalid University to overcome the difficulties and problems resulting from extrinsic motivation and showing ways of attaining positive (intrinsic) motivational make up that initiates true, life-long learning.


The radical restructuring of the economic mechanism requires the more intensive, deeper analysis of socialist production relations, and especially their underlying foundation—socialist property. In our view, there exist great possibilities for more substantive research on these questions which are associated with the reexamination of existing simplistic ideas, stereotypes, and dogmas that have demonstrated their theoretical and practical groundlessness.


Adhesives are employed in external strengthening of concrete structures by Carbon Fibre Reinforced Polymer (CFRP). Carbon-based composites are currently the most common type used to increase the strength of concrete members. The application of Carbon Fibre fabrics (CF fabric) to concrete members involves the use of a compatible bonding agent, and it is the modification of such bonding agents that is investigated in this paper. The investigation involves examining the effects of adding different concentrations of vapour-grown carbon nanofibres (VGCF) (0.5 wt%, 1 wt%, 1.5 wt% and 2 wt%) on the thermal and mechanical properties of the bonding agent. The effect of modification on the glass transition temperature and heat flow of the modified adhesive was explored using Differential Scanning Calorimetry (DSC) technique. It was found that Tg reduces slightly or remains the same with the addition of VGCF to Part A of the adhesive and the highest reduction in Tg was found when Part A was reinforced with 2 wt % VGCF. Agglomaration of the fibres was observed when VGCF was introduced into MBrace® Saturant epoxy adhesive using the speed mixer and a random orientation for the fibres was noted within the epoxy matrix. Peeling-off of CF fabric was the common failure mode as the loaded CFRP/concrete system was subjected to the combined effect of temperature and humidity after short periods of exposure to such severe conditions.


This article makes a complete estimate analysis on the tourism resource of Quanzhou Puppet show's estimate from the resource,the market and the product based on the RMP analysis.It displays there is a profound history and culture,prominent regional features,wide drama markets and high tourism value in Quanzhou puppet show,but a short tourism market share at the moment.This article points out a development assume on the united development of puppet show and created industry,the space combination development of puppetoon product and the various introduction of puppet show.As suggested at the same time that to develop created?tourism by intellect,official and government as guarantee measures of tourism development.


Objective:By discussing the early treatment of cardiopathy of pregnancy-induced hypertension syndrome(PIH) and lowering the death rate of the pregnant woman and lying-in woman.Methods:The cause, treatment and influence of the mother and the baby were analysed in 20 patients of cardiopathy of PIH retrospectively. 200 patients of PIH were as control group. Conclusion:The cardiopathy of PIH were related to anemia, hypoproteinemia, ascetic and incorrect treatment of dilation. we must pay more attention to the inducement of the cardiopathy of PIH. After controlling the heart failure, we must terminate the pregnant immediately in order to decrease the complication.


Building upon the theoretical outline of the first chapter, the second introduces the reader to the predominant discourses (e.g. psychology, family health and welfare, sociological and academic masculinity literature) which inform and structure modern fatherhood. Taking a historical perspective, discussion begins with consideration of the emergence of the family movements of the late 1800s and early 1900s. One of the most interesting aspects of the book is the historical account in which the main constitutive


A key component of the functioning of a market system of education is the provision of information to consumers. While marketing may be used by schools to provide information to consumers. The marketing information may appeal to some consumers and not others. This study examines independent schools marketing on their websites and how it appeals to consumers in need of special support. The findings show that these schools market their goals and values, studentship, methods and programmes, services as well as facilities. The marketing by these schools may not appeal to students in need of special support in the failure to provide relevant and adequate information to them and framing of their studentship that does not include students in need of special support as well as the focus on academic performance.


A human carcinoma xenograft model was established with resistant KB-A-1 cell line in order to investigate whether (2 )epigallocatechin gallte (EGCG) can reverse doxorubicin (DOX) resistance in vivo. EGCG could sensitize the tumors to DOX as indicated by a considerable reduction of tumor weights. The combination of DOX with EGCG increased the DOX concentration by 51% in the tumors, and increased DOX-induced apoptosis in the tumors compared with DOX alone. In addition, the combination schedules appeared to be well tolerated. We conclude that EGCG could chemosensitize resistant tumor cells to DOX in vivo through an increase in the accumulation of DOX in the tumors. q 2004 Elsevier Ltd. All rights reserved.