Generally designers neglect these infill walls in as 'non-structural' and treat the frames as conventional reinforced concrete frames. However, the presence of infill the frame alters the overall behavior, especially when the structure is subjected to later loads. The objective of this study was to investigate the behaviour of 2D quarter scale reinforced concrete square frame with various brick infills under diagonal static loading. In this investigation the performance of M20 grade of concrete frame mix designed as per IS method with four types of masonry infilled frames such as reinforced concrete frames without masonry infill (Bare frame), reinforced concrete frames with brick masonry infill, reinforced concrete frames with flyash brick masonry infill and reinforced concrete frames with hallow block masonry infill were cast and studied. The study discusses the strength of the 2D frame under ultimate diagonal loads till failure. Conclusions are made based on the experimental investigations.


From the Departments of Neurology (Dr Weinberg and Mses Schraufnagel and Harper), and Pediatrics (Dr Weinberg), University of Texas Southwestern Medical Center—Dallas, and the Pediatric Behavioral Neurology Program (Dr Weinberg), Division of Pediatric Neurology, Children's Medical Center of Dallas, Dallas, TX, and the Departments of Pathology and Neurology (Dr Brumback), Section of Neuropathology, University of Oklahoma College of Medicine, and Veterans Affairs Medical Center, Oklahoma City, OK. Address correspondence to Dr Warren A. Weinberg, University of Texas Southwestern Medical Center at Dallas, Division of Pediatric Neurology, Pediatric Behavioral Neurology Program, 6303 Forest Park, Suite 13.350 Dallas, TX 75235-9119. Children and adolescents with various learning and behavior disorders are frequently referred to child neurologists for evaluation and treatment. A number of recent articles have established diagnostic criteria that permit definitive diagnosis of specific clinical entities. 1-~3 Once a diagnosis is established, the clinician needs to be able to institute an appropriate management plan, which may include pharmacotherapy. Over the past 20 years, the Pediatric Behavioral Neurology Program of the Division of Pediatric Neurology at Children's Medical Center and University of Texas Southwestern Medical Center at Dallas has suc-


PurposeThis study aims to scrutinize time-varying return and volatility interlinkages among major cryptocurrencies, NFT tokens and DeFi assets between 1 July 2018 and 19 February 2023 and determine optimal portfolio allocations and hedging effectiveness under different portfolio construction techniques.Design/methodology/approachThis work examines time-varying return and volatility interlinkages among major cryptocurrencies, NFT tokens, and DeFi assets between 1 July 2018 and 19 February 2023. To this end, the time-varying parameter-vector autoregression (TVP-VAR)-based connectedness methodology of Antonakakis et al. (2020) This approach is an extended version of the Diebold–Yilmaz (DY) method (Diebold and Yılmaz, 2014) and has advantages over the original DY. First, unlike the DY, it is free of the selection of a particular window size. Second, it has robustness for the outliers. Furthermore, following Broadstock et al. (2022), the author estimates time-varying optimal portfolio weights and hedging effectiveness under different portfolio construction scenarios.FindingsThis study's results indicate the following results: (1) The overall connectedness indices prominently capture well-known financial/geopolitical distress incidents; (2) the leading cryptocurrencies (ETH, BTC and BNB) are the largest transmitter of return shocks, while LINK and BTC are the largest transmitters/recipients of volatility shocks; (3) cryptocurrencies, NFTs and DeFi form distinct cluster groups in terms of return and volatility connectedness; (4) the connectedness networks estimated around the 2022 cryptocurrency crash and the FTX's filing for the bankruptcy are characterized by the strongest return and volatility interlinkages; (5) optimal portfolio strategies computed by different portfolio construction techniques display similar motifs and have sustained growth paths except for some short-lived drop backs.Research limitations/implicationsThis study's findings imply several policy suggestions for investors, stakeholders and policymakers. First, the study's time-based dynamic interlinkages can help market participants in their optimal portfolio decisions. In particular, the persistent net receiving roles of the DeFi assets and the NFTs throughout the episode, especially around the financial/geopolitical turmoil, underpin their safe haven potentials (Umar et al., 2022a, b). Finally, since the total connectedness indices (TCIs) are prone to significantly increase around financial/geopolitical burst times, these tools can be valuable for policy makers to monitor risk.Originality/valueThe contribution of knowledge is at least threefold. First, the author focuses on the dynamic time interlinkages among major cryptocurrencies, NFTs and DeFi assets in July 2018 and February 2023 considering the prominent recent financial/geopolitical incidents. Second, the author estimates network topologies of dynamic connectedness around financial/geopolitical bursts and compared them in terms of interlinkages. Finally, the author calculates the time-varying optimal portfolio allocations and hedging effectiveness under different portfolio construction techniques.


In this review, we present recent advances in the transition metal catalyzed electro-organic transformations since 2000. The review mainly focuses on C-C and C-heteroatom bond-forming reactions along with miscellaneous reactions. Electro-organic synthesis attracts the attention of chemists due to no use of equivalent amount of chemical oxidants. Since electron is a mass free reagent, atom economy of electro-organic reactions is high and hence they are green reactions. We present articles in which transition metal catalysts are regenerated by electricity. Besides, reactions due to sacrificial anodes are also presented.


Based on the theory of elastic plates and shells,the concept of equivalent isotropic solid plate elaborated for perforated tubesheet,the new methodology to determine the effective elastic constants by mo-dal analysis of such plates is described.The computing formula of effective elastic constants for plates with hetero-diameter dual-holes are given in terms of the stiffness superposition method.By modal approach,the effective elastic constants of support plates with various perforation shapes popularly used in steam generator,such as hetero-diameter holes,trefoil and quatrefoil holes,are obtained.The universal relationship between the effective elastic constants and the mass fraction are established,which can be used for perforated plates with any arbitrary hole shape.The study results indicate that the curves for calculating effective elastic con-stants adopted in ASME are improper in non-circular hole perforated plates and shall not to be applied in the support plates and tubesheet of steam generator.


As the centennial anniversary of Mexican independence, 1910 was not only a peak year for representations of Mexican national identity, but also for debates on feminism, the "Mexican woman," and the nature of her role in society (Cano 1998: 106). Concerns regarding feminism and nationalism dovetail in Genaro Garcia's centennial biography of independence figure Leona Vicario, an exception to the standard publications emanating from the Mexican literate sectors between 1880 and 1911 in terms of its portrayal of women and nation. This largely unexamined biography sheds light on feminist Mexican thought, and viewed in conjunction with Garcia's writings on women's legal rights in Mexico, stands out at as a formidable re-writing of the position of woman in the Mexican nation.


According to the view-point of asset-liability,the differences between accounting profits and taxable profits are temporary differences between the carrying amount of an asset or liability in the balance sheet and its tax base.This paper systematically analyzes the temporary differences from two aspects of initial recognition and further recognition,and then summarizes the similarities and differences between temporary difference based on asset-liability view and timing difference and permanent difference based on revenue-expense view.


The frequency characteristics of the microstrip line with DGS are simulated by means of 3-D field analysis, and its equivalent circuit and equivalent parameters extraction are analyzed. Then the influences of C shape and the material permittivity on frequency characteristic are discussed using the simulation with Taguchi method.


Soils between ground surface and water table play an important role in direct foundations, hydrology and agriculture. Pore water pressure is negative and most of the time soils are unsaturated: they constitute the unsaturated zone. Soils in this zone are exposed to weather; water is infiltrating or evaporating according to season and is transferred through the unsaturated soil, emerging at the water table. For the study of the hydrological situation, observations have been carried out on clay soils at Mielan basin and on sand like residuals stocked in waste fills at Potash Mines, Rhine site. A reduced model is adopted to study infiltration, retention and drainage terms of the hydrological balance. Similitude conditions are defined and results for two soils compared. (A) For the covering abstract see IRRD 881647.


Based on the survey data of 310 migrant workers in Hebei province,this article analyzed the correlation between migrant workers' individuality,job characteristics and their employment.It found that,viewing from the terms of individual characteristics:(a) income of male subjects were significantly higher than that of the female participants;(b) married childless participants changed their job most frequently,while those with children had longest probation period;(c) participants with higher education degree had higher wage and less working hours,and the frequence of their changing job was larger;(d) the age of the participants had a negative effect on income.In terms of job characteristics:(a) considering from the post of the samples,the sales staff had the least working hours and length of service,since they changed their job frequently,while foremen and supervisors earned more;(b)considering from the working field,construction workers didn't change their job often and their length of service was relatively longer,and the working time of workers of dining industry as well as entertainment industry was the longest,and the income of manufacturing samples was the highest.


The ant Atta laevigata, dwells in the departments of Santander and Casanare in Colombia where they are used as food by the people, attributing aphrodisiac properties. We evaluated current methods of collection, processed and materials used in the production of ant toast, and according to the deficiencies found were proposed effective methods and new processes to make better use of this resource. The


The contribution of the three different splice elements was studied. Splice strength is primarily due to intermingling/tucking. Twisting also contributes significantly to splice strength, but the contribution of wrapping to strength is minimal.


The current state of ionospheric wind dynamo theory is reviewed. Observational and theoretical advances in recent years have permitted more accurate models of the dynamo mechanism to be presented than previously, which have lent further credence to the validity of dynamo theory as the main explanation for quiet-day ionospheric electric fields and currents at middle and low latitudes. The diurnal component of the wind in the upper E region and lower F region appears to be primarily responsible for average quiet-day currents, although other wind components give significant contributions. Observationally, there is a need for better spatial and temporal coverage of wind and electric field data. Theoretically, there is a need for further consideration of the mutual dynamic coupling among winds, conductivities, electric fields, and electric currents, and for better modeling of nighttime conditions.


Test and Measurement task can be done without limit of time and space by PDA with virtual instrument technology. The structure of PDA based virtual instrument is described firstly. Then PMDS(PDA Measurement Develop System) which can construct virtual instruments efficiently using component technology is introduced, it can enhance quality and efficiency of instruments. Finally, portable spectrum analyzer and mobile temperature monitor is built with PMDS to illuminate the usage of PMDS.


Diimide Carrying β‐Cyclodextrin Converts Double-Stranded DNA to a Rod-Like Structure Shinobu Sato, Yuta Umeda, Satoshi Fujii, and Shigeori Takenaka* Bioconjugate Chem. 2015, 26 (3), 379−382. DOI: 10.1021/bc500535n A incorrect version of the structure of Ferrocenylnaphthalene Diimide Carrying β-Cyclodextrin (mirror image) was used as the abstract graphic and compound 1 structure on page 379. The correct representations are shown below.


Existing degree-based method uses node degree as descriptor to extract image transition region, and achieves image thresholding via transitional pixels' gray levels. The method is sensitive to salt & pepper noise. To solve this problem, a modified version is presented in this paper. The proposed method utilizes orientation information and characteristics of salt & pepper noise to distinguish transitional pixel and noise, improving accuracy of transition region extraction. In addition, we suggest a scheme for ruling out this type of noise in image thresholding result, further enhancing its noise immunity for salt & pepper noise. The modified version was compared with original degree-based method and famous local entropy-based one on a variety of images, and experimental results show its effectiveness and noise immunity for salt & pepper noise.


Thank you for downloading understanding and helping the schizophrenic a guide for family and friends. As you may know, people have look hundreds times for their favorite novels like this understanding and helping the schizophrenic a guide for family and friends, but end up in malicious downloads. Rather than reading a good book with a cup of tea in the afternoon, instead they juggled with some harmful virus inside their computer.


Quasi-phase-matching (QPM) technique has been successfully applied in nonlinear optics, such as optical frequency conversion. Recently, remarkable advances have been made in the QPM generation and manipulation of photon entanglement. In this paper, we review the current progresses in the QPM engineering of entangled photons, which are finished mainly by our group. By the design of concurrent QPM processes insides a single nonlinear optical crystal, the spectrum of entangled photons can be extended or shaped on demand, also the spatial entanglement can be transformed by transverse inhomogeneity of domain modulation, resulting in new applications in path-entanglement, quantum Talbot effects, quantum imaging etc. Combined with waveguide structures and the electro-optic effect, the entangled photons can be generated, then guided and phase-controlled within a single QPM crystal chip. QPM devices can act as a key ingredient in integrated quantum information processing.


Peter W. de Leeuw, MD, PhD Cornelis T. Postma, MD, PhD Abraham A. Kroon, MD, PhD Author Affiliations: Department of Medicine, University Hospital Maastricht, Maastricht, the Netherlands (Drs de Leeuw and Kroon) (p.deleeuw@maastrichtuniversity .nl); and Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands (Dr Postma). Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.


With the development of building of digital campus,campus data centers are built by many schools.Building campus data center can integrate resources.The IT resources of data center management was classified failure management,configuration management,performance management,safe management,modification management,problem management,issue management,service quality management,cost management,capacity management,availability management,durative management.This system adopts Linux,Apache web server,MySQL,C,PHP and Perl.


Radioaotive gibberellin A) (3H-GA1) wasinjected intoexcised fruits ofpeas andJapanese morning glory. Thesewerethengrowninsterile culture tomaturity andthe label wasfolowedintheseedsduring further development andsubsequent germination. Duringdevelopment ofbothpeaandmorning-glory seeds a large partoftheradioactivity becameassociated withtheaqueous fraction, while another partofthe3H.GA1wasoonverted into2 new,aoidic, biologically active compounds, designated X1andX,.A reGatively small partoftheneutral compounds oould beconverted backto3H1-GA1, X1,andX,bymeansof mildaoidhydrolysis. During germination ofpeaandmorning-glory seedts, partofthebound comMpounds wasreleased intheformof3H-GA1, X1andX2while, particularly during rapid seedling growth, afurther conversion of1H-GA1, mainly toX1,tookplace. Inpeaseedlings, growth during thefirst 2to3days after imbilbition wasnotaffected tbyAmo-1618, aninhibitor ofgibberellin biosynthesis. This, inconjunction withthefindings on theinterconversions between freeandbound3H-GA1 suggests that, atleast inpeas,early seedling growth mayat least partly beregulated bygibberellins released froma boundformwhich was formed during seeddevelopment.


Social science research notes that racial context is related to attitudes toward social issues; however, surprisingly little research has examined how the impact of racial context on attitudes is activated. The aim of this article is to examine racial context "effects" for policy preferences, but to do so within a broader perspective. This article extends the literature on racial attitudes by considering a conditional relationship between racial and ethnic context and socioeconomic context and expanding racial context to include multiple racial and ethnic groups. The findings indicate that racial and ethnic contextual effects do emerge; however, these effects are conditional on the socioeconomic context in which an individual resides. Specifically, high socioeconomic contexts and highly diverse contexts are related to higher levels of support for racial social issues; however, contexts characterized by low socioeconomic context and high racial and ethnic diversity are associated with lower levels of support for such issues.


The type of search where a robot's track takes it on a path where its sensors can detect all mines located in the area is referred to as area coverage. Planning this track is an issue in robotics and is complicated when the robot is legged due to the reduced precision of its movements. Cyclic genetic algorithms have been used as a method for learning the cycle of turns and straights required for a hexapod robot to solve the area coverage problem. Although successful in a static environment, the learning system needed an anytime component to make it adaptable enough to be used in practice. This paper discusses the creation of a viable learning system by adding the anytime learning technique of co-evolving model parameters. Tests in simulation demonstrate this system's usefulness in generating search patterns despite changes in the robot's performance.


The conditions required to establish the stability of incomplete charge transfer in the ground state of a 1:1 segregated-stack organic compound have been examined for a system involving finite-transfer integral between nearest-neighbor molecules along the donor and acceptor stacks. Molecular ionization energy, crystalline Madelung energy, as well as band or delocalization energy have been included. The three cases investigated, namely, no correlation between electrons on a stack, strong on-site correlation as well as strong nearest-neighbor correlation suggest that correlation between electrons (holes) on the same stack is important in establishing incomplete charge transfer in an organic compound such as TTF-TCNQ (tetrathiafulvalenium-tetracyanoquinodimethanide).


he article describes five blocks of Cosmococa program in progress from Neville de Almeida and Helio Oiticica trying to show some procedures for its construction and some effects that each one provides. Initially each block calls for an immersion in a sensory experience. At the same time, the elements involved in the composition of the serie inflate against offset habits and current views in order to stimulate unexpected openings through the aesthetic experimentation. Key words : Cosmococa; aesthetic experimentation; artistic composition.


The objective of this study was to identify products of the traditional medicine (vegetable and animal) that are marketed in Boa Vista, State of Roraima and describe a preliminary profile on the way of commercialization of these products. Hundred and seventeen products were identified as fallow: 100 (85,5 %) of vegetable origin and 17 (14,5 %) of animal origin. The main vegetable products were Jatoba (Hymenaea courbaril), Barbatimao (Stryphnodendron adstrinfens), Sucuba (Himatanthus articulatus), Xixua (Maytenus guianesis), Copaiba (Copaifera officinalis) and Pata-de-vaca (Bauhinia ungulata). The Pirarara fat (Phractocephalus hemioliopterus) was the animal product more searched by users. Most of the products marketed in Boa Vista come from Northeast region of Brazil, although Roraima presents a rich medicinal flora little explored in a sustained commercial way.


This paper discusses hybrid state saving for applications in which processes should create checkpoints at constant intervals and can hold a finite number of checkpoints. We propose a reclamation technique for checkpoint space, that provides effective checkpoint time arrangements for a rollback distance distribution. Numerical examples show that when we cannot use the optimal checkpoint interval due to the system requirements, the proposed technique can achieve lower expected overhead compared to the conventional technique without considering the form of the rollback distance distribution. key words: distributed checkpointing, hybrid state saving, checkpointspace reclamation, time arrangement rotation


Background: This study was carried out to elucidate the effects of the oral administration of three types of herbs extract, stick cherry, soybean seed, and licorice root on concentration of the serum hormone, progesterone, testosterone, and estradiol in albino male mice. Objective: we investigated the impact of biological activity of stick cherry, soybean seed, licorice root extracts on serum concentrations of reproductive hormone as compared with untreated group. Materials and Methods: A total of 84 male mice were used in the experiment. The first group (G1) was the control group which comprised 11 mice treated with 5.0 mL/day distilled water. The remaining 63 mice were divided into (G1), (G6), and (G8). Each group comprised 11 mice. The mice in these groups were orally treated for 11 days with 5.0 mL/day stick cherry ethanol extract, soybean powder hexane extract, or licorice root ethanol extract at concentrations of 15, 15, and 15 mg/kg/day, respectively. Results and Discussions: Results show the effect of stick cherry ethanol extract induced a significant increase in serum concentration of progesterone and testosterone, and a remarkable decrease in estradiol concentration. Soybean extract induced a significant increase in serum concentration of progesterone, testosterone, and estradiol in the treated group compared with the untreated group. No significant effect statistically was found in progesterone, estradiol, and testosterone levels occurred in the group treated with licorice root extract compared with the untreated group. Conclusion: The extracts of stick cherry, and soybean seed exerts a remarkable effect on serum hormone concentration of reproductive organs, progesterone, testosterone and estradiol. Licorice root extract did not show any significant difference for all hormone levels. These extracts might be used as drugs and improve the function of reproductive organ or used as antifertility agents. There is no pharmacological or medical studies have evaluated the effect of stick cherry extract on reproductive hormones in male mice. Meanwhile, limited data and few references are available on the effects of soybean extracts licorice root on the serum hormone levels of reproductive organs.


Universal regularities of the Fourier spectrum of signal, generated by complex analytic map at the period-tripling bifurcations accumulation point are considered. The difference between intensities of the subharmonics at the values of frequency corresponding to the neighbor hierarchical levels of the spectrum is characterized by a constant $\gamma=21.9$ dB?, which is an analogue of the known value $\gamma_F=13.4$ dB, intrinsic to the Feigenbaum critical point. Data of the physical experiment, directed to the observation of the spectrum at period-tripling accumulation point, are represented.


This paper discusses the hermeneutic relationship between personal and social ethics in Christian religious communities in the society. Ethics or a moral value is the division of Philosophy that comprises organizing, preserving, and applauding perceptions of correct and incorrect behaviour. As a division of Philosophy, Ethics examines the queries "What is the greatest manner for individuals to live?" and "What activities are correct or incorrect in precise situations?" In exercise, personal and social ethics try to find a resolution to questions of human standards, by outlining conceptions like decent and wicked, good and bad, equity and iniquity, integrity and misconduct. As a field of logical probe, decent value also is associated with the areas of moral sensibility, expressive morals, and value theory. Definition of the word ethics appears to be a divergent term since several explanations are related to it.


Background: The Back pain affects about 20% of the population in Bangladesh in each year between the ages of 30-60 years. A well-defined pathology is identified in only about 15% of patients.
Objective: To identify the association of hyperuricemia in patients with chronic low back pain.
Materials and Methods: A descriptive cross-sectional study was performed on 180 patients among the ages of 18 to 75 years with chronic low back pain (CLBP). Data was collected through a structured questionnaire. X-rays and Magnetic Resonance Imaging (MRI) of the lumbosacral spine had been used to evaluate any findings in terms of low back pain. Serum uric acid (sUA) levels had been tested and recorded.
Results: Joint pain (p < 0.001), lumbar disc prolapse (p = 0.023), and disc degeneration (p = 0.011) were more in High-sUA than Low-sUA group. Female patients in H-sUA group had significantly higher occurrence of joint pain(p = 0.002), lumbar disc prolapse (p = 0.019), and disc degeneration (p = 0.004) than L-sUA group. In regression analysis, female sex (p = 0.036), duration of CLBP (p = 0.031), and sUA level (p = 0.025) were associated with radiological findings. In female patients association of duration of CLBP (p = 0.046) and sUA (p = 0.009).
Conclusion: The serum UA level was significantly associated with CLBP in female patients. More studies are warranted to explore whether the two conditions exist simultaneously or there is a direct causal relationship between the conditions.
KYAMC Journal. 2022;12(04): 213-217


Disasters have multitude of effects on the victims; as the direct loss and damage during disasters and the indirect consequences continue for years. In the developing world disasters have colossal impact where the resources are scarce, disaster relief systems are inadequate and post-disaster long-term care is abysmally poor. Psychiatric morbidities are observed in a large majority of affected population and these often become chronic. It is imperative to study how the victims cope following the catastrophic disasters, the relation between various coping strategies and manifest morbidities and variations across disasters and cultures. This article reviews the available literature regarding coping following various disasters and summarizes the coping strategies employed by disaster victims around the world. Variations in coping across cultures are highlighted and areas for therapeutic intervention are suggested. These understandings in coping may help in facilitating positive coping and developing culture specific and appropriate intervention programmes.


The quantum cascade laser, operates over an extremely wide wavelength range in the mid-infrared with high output power and low power consumption (<;1W). A new generation of devices show enhanced wavelength multiplexing and tuning agility capabilities as well a frequency comb generation over more than 100cm-1.


English teaching has always attracted much attention. However, the processes of its transmission and acquirement is often divided into two separate parts, which seriously hinders the effective implementation of its objectives. Teachers attach particular importance to the choice of the curriculum structure and teaching material. Students are busy comprehending the assignments their teachers deem important. Under such a scenario, the effective acquisition of knowledge and the development of sustainable comprehensive abilities are ignored. The random forest algorithm in machine learning applications could play important role improving on the current English teaching system. A random forest model is constructed using a decision trees selection method, which focuses on 19 attributes of the English teaching model. Results show, to begin with, that the indigenous teaching plan and environment fail to adapt to the pace of knowledge iteration in the era of big data. Moreover, interactions between teachers and students appear to be shallow with little constructive interaction, causing a decline in the relationship between teachers and students. Last, there is still no signs of any legitimate construction in terms of in-person English teaching, relativity attribute, corpus and platform. Therefore, this paper has proposed a new English teaching model to adapt to the current college English teaching environment. The experimental results show that the method is effective and feasible for the current college English teaching.


The business environment of enterprises could be difficult to obviate redundancy to filtrate data source occurred on data integrated to standard rules and meta-data and to produce integration of data and single viewer in geographical and spatial distributed environment. Specially, To can interchange various data from a heterogeneous system or various applications without types and forms and synchronize continually exactly integrated information#s is of paramount concern. Therefore data hub system based on SQL/XMDR message to overcome a problem of meaning interoperability occurred on exchanging or jointing between each legacy systems are proposed in this paper. This system use message mapping technique of query transform system to maintain data modified in real-time on cooperating data. It can consistently maintain data modified in realtime on exchanging or jointing data for cooperating legacy systems, it improve clarity and availability of data by providing a single interface on data retrieval.


Kingston's 6,500 council tenants and leaseholders could soon be playing a lead role in running the borough's Housing Service, if plans for an innovative community housing trust go ahead.


Mixed tumor in the same lymph nodes is extremely rare and no previous reports have described mixed tumor comprising urothelial carcinoma and malignant lymphoma.


Assessing the effects of sediment inhomogeneity on the core stratigraphy and on proxy records is essential to perform reliable climate reconstructions from marine sediments. Inhomogeneities can stem from sediment mixing (e.g., bioturbation) which destroys the temporally layered climatic information stored in proxy carrier. Thus, in addition to the measurement error, the time-uncertainty in radiocarbon-dated sediments must be taken into account for depth-age modelling in order to obtain an unambiguous time scale.

Here, we present a case-study based on a boxcore (OR1-1218-C2-BC) from the South China Sea (2208 m water depth) covering the last 20 kyr. The boxcore was divided into nine sub-cores by a grid of 3 x 3 (each sub-core is 8 x 8 cm with a length of 34 cm), yielding a total surface area of 576 cm2. This sampling scheme offers the possibility for detailed, three-dimensional analyses on small spatial scales. Radiocarbon measurements were performed in every sub-core for seven depth layers, each with a fraction of 200 crushed and well mixed foraminifera (Trilobatus sacculifer, 250 – 350 µm) to study the horizontal sediment heterogeneity. In addition, small sample (5 specimen) replicate radiocarbon measurements from a single sediment sample allow to estimate the age heterogeneity within a 1 cm sediment slice and thus the vertical mixing from bioturbation. The replicate radiocarbon dates suggest a bioturbation depth of around 12 cm; however, the downcore radiocarbon dates show no clear sign of a well-mixed bioturbation layer. Using statistical analysis (e.g., spatial correlation measures and variance analyses), we separate the errors from the radiocarbon measurements, the finite sample size and both the vertical and horizontal heterogeneity. Comparing the radiocarbon dates in the sub-cores indicates a small horizontal heterogeneity compared to the vertical mixing.

The three-dimensional data set allows us to quantify the effect introduced by (post-depositional) sediment mixing on the age-estimate as well as on the proxy signal and to discuss the effects on low-sedimentation climate records. This will provide a better quantification of uncertainties within proxy time series.


The present paper is an attempt to demarcate the fields of Semantics and Pragmatics. The traditional problem of intrusion of Semantics upon the field of Pragmatics may be a consequence ci the conception of Semantics as the study of designation. This relation between a linguistic sign and an extralinguistic entity involves a connection with contextual parameters typical of the domain of Pragmatics. As a solution to this problem, the present proposal is to define Semantics on a functional, structural criterion. This entails conceiving Semantics within the domain of the representative function of language, being the systematic study of signification its only object of study. This definition, then, favours a view of Pragmatics as the study pertaining to the domain of the expressive-appellative function of language, and focusing on meaning as conveyed in a communicative situation. Delimitation of scientific fields of study is based on three major factors: subject matter, methodology and purpose. Variation in the subject matter is an unquestionable proof that a change of discipline is operating. It usually entails a change in methodology and ;n purpose. By contrast, the opposite does not always hold: a methodological change may only be indicative of different approaches towards the same object of study. Consequently, a change of discipline does not necessarily occur. This being so, delimitation of the fields of Semantics and Pragmatics should virtually pose no problems if based exclusively on their respective objects of study. However, due to the indeterminacy of their objects of study, the problem does exist. An overview of the literature shows that the demarcation of each of the disciplines under consideration has concentrated on the traditional division between the two fields. Applying a strict criterion, Semantics has been viewed as the science concerned only with truth conditions, or semantic content; that is, with propositions that communicate information about the world (cfr. Lewis 1972). Pragmatics, for Us part, has been conceived as the study of meaning minus truth conditions (cfr. Gazdar 1979). The latter definition is based on Grice's (1975) argument that utterances, by means of the Cooperative Principle (CP), convey more information than they apparently express, and that the hearer arrives at that extra information by means of assumptions once any of the maxims of conversation is violated by the speaker.


The incidence and size of the larval tapeworm burden in young, middle-aged, and old confused flour beetles was studied. The influences of sex and length of starvation period were also observed. Virgin beetles from young parents were permitted to feed for 24 hours on whole gravid proglottids and then returned to the medium for at least fourteen days prior to being preserved, dissected, and examined for cysticercoids. A quantitative approach to feeding eggs to the beetles was unsuccessful. Old females generally had a significantly smaller burden and incidence of cysticercoids when compared with young or middle-aged females, whereas middle-aged males generally had a significantly higher incidence only when compared with young or old males. Apparently an age resistance to the establishment of H. diminuta in T. confusum occurs in the females only.


Java service has become real-world critical business service,and its availability is the key of availability of business system based on java technology.This paper provides an effective method of improving availability of java service by combining the three technologies of VMM,JVM and SAR.This method makes use of the characteristics of the three technologies,such as advanced manageability of VMM,controllable runtime environment of Java services of JVM,and means of dealing with software aging of SAR.


The results of the assessment on the technology of fishing assistance using Deeper Pro fish radar by capture fishermen on Barrang Island Caddi are the objectives of this paper. The results of the study are reviewed in terms of functional and usability. The results of the study show that Deeper pro as a fish radar tool is effective in detecting the presence of fish in the sea depth up to 80 meters. The amount of fish at a certain depth can be detected in the form of visual illustrations both in number and depth. The use of features in Deeper Pro can be easily mastered by fishermen catching Barrang Caddi. The Deeper Pro fish radar device is functional and usability usable in use by barrang caddi fishermen in assisting fish skill.


The Vanuatu Cultural Information Network (VCIN) is an on-going initiative of the Vanuatu Cultural Centre (VCC) to organise, manage and protect its digital archives.1 These archives include those of Vanuatu's National Library; Public Library; National Museum; National Photo, Film and Sound Archive (NFFSA); Vanuatu National Heritage Register; Women's Culture Program; Young People's Program; Traditional Resource Management Program; and Sand Drawing Project. Together these sections comprise the Vanuatu Cultural Centre.


Purpose
Emergence is a key concept in service-dominant (SD) logic; however, the literature is neonatal on the underlying mechanisms that lead to emergence within service ecosystems. This study aims to address the call by Vargo et al. (2022) for understanding the role of actor engagement in emergence of novel outcomes, by identifying a process of how various actor roles in entrepreneurial ecosystem (EE) emerge as resource through the actor engagement.

Design/methodology/approach
Following a longitudinal design, this study conduct interviews from 20 respondents over eight months in three phases (group interviews, post-training, post-funding). This study analyzes the respondents' engagement in an entrepreneurial service context. This study uses qualitative inductive approach and thematic analysis.

Findings
Results show that actor roles emerge as role expectations from essential provider and beneficiary position in a service ecosystem through actor role readiness, manifested as engagement properties in the actor engagement process. This study identifies five actor roles and their corresponding role readiness dimensions that emerge. Based on these propositions through which the authors position generic actor roles emergence within the actor engagement process in a service ecosystem.

Originality/value
This paper advances the understanding of micro-level process in emergence literature in SD logic by providing a conceptual understanding of emergence of actor roles as a resource through actor engagement. By grounding the study in EE, this study provides empirical evidence to the underlying mechanisms at the micro level of resource emergence process in a service ecosystem.


This paper mainly presents the thermal stability of a quasi-isotropic strand composed of stacked high temperature superconducting coated conductors (CC). The strand was sheathed by different kinds of metal such as copper and aluminum. The quench characteristics of the strand, including the minimum quench energy (MQE) and the quench propagation velocity (QPV), were simulated by software Comsol5.0. The simulated results show that the thermal stability of strands with copper sheath is higher than that one with aluminum sheath.


When William Cowper introduced these verses into The Task in 1785 the gigantic Handel Commemoration of the preceding year still rang fresh in the ears of thousands of Englishmen. In 1783 several musical amateurs had proposed to commemorate the centenary of Handel's birth and the twenty-fifth anniversary of his death by a series of stupendous Handel performances on a hitherto unprecedented scale, and the first great Handel Festival had accordingly taken place in Westminster Abbey in the late spring of 1784, warmly patronized by George III and the greater nobility, and enthusiastically attended by more than three thousand persons from every corner of the kingdom. A vocal and instrumental band of 525 performers, "inflamed and actuated by the Muse of Handel," made this mammoth celebration "the most splendid tribute ever paid to posthumous fame," and current periodicals exhausted every superlative in praising the grand occasion. The European Magazine reported that "the immense volume and torrent of sound, was almost too much for the head or the sense to bear — we were elevated into a species of delirium." The performance was in "so superior, and so exalted a stile, that it must not be subjected to the rules of pettyfogging criticism," since "so grand and beautiful a spectacle, with at the same time a feast so rich and perfect, has not been presented to the public eye within our memory."


With the rise of technologies such as mobile Internet, 5G networks and artificial intelligence, the development of Internet of Vehicle Information Security (ICVS) has become the mainstream and direction for the future development of the automotive industry. ICVS, people, roads, clouds, and APP constitute a complex network of vehicles. As part of the Internet, vehicle networking will inevitably face various complex information security threats and risks. This paper aims to design a kind of security situation awareness of Internet of vehicles based on intrusion detection protection systems (IDPS). By collecting the security data of car, app and private cloud for big data analysis, the whole smart car security situation awareness system is constructed. The system can be used to analyze potential threats, send out warnings, and carry out emergency responses.


A signal switching module in digital multimedia central control system is designed to switch signals freely in multimedia classroom. The multimedia center control system is designed, and MCU is employed to control audio, video and VGA switching modules.


A partnership that was established to provide cross-cultural learning for senior-level community health nursing students from the United States also provided a learning opportunity for nurses at a pediatric neurosurgical hospital in Uganda. The faculty who accompanied the students on the study abroad to the CURE Children's Hospital of Uganda provided an educational session on critical thinking in response to request from the hospital administrators. Learning outcomes were evidenced through informal one-on-one interactions following the sessions. Even a small contribution such as this teaching intervention in cross-cultural exchange may affirm the belief that "each drop counts" as the nurses may obtain skills that enhance their ability to contribute to saving the lives of their patients.


Protocadherin 7 (PCDH7) is a member of PCDHs belonging to the cadherin superfamily. It was recently identified as potential tumour endothelial maker (TEM). Although it is expressed in many solid tumours, its function in endothelial cells and its binding partner(s) on endothelial cell surface are unknown. Thus a major aim of this thesis was to determine the role of its extracellular domain (ECD) in endothelial cells and to potentially identify novel ligand(s) of its ECD on endothelial cell surface. Recombinant human Fc fused hPCDH7 ECD significantly inhibited endothelial network formation, cell proliferation and chemotaxis in vitro. This was mediated by the first five N-terminal cadherin repeats of the ECD. However, no ligands of the ECD were identified. A second part of this thesis involved the identification of novel TEMs from colorectal cancer. Apelin (APLN), endothelial cell-specific molecule-1 (ESM-1), matrix metalloproteinase-12 (MMP12) and epiregulin (EREG) identified as potential candidates will be further validated. Additionally, the angiogenic potential of protein C receptor (PROCR), chromosome 1 open reading frame 54 (C1ORF54) and stabilin 1 (STAB1) which were enriched in tumour endothelium was investigated, with a role for PROCR in endothelial network formation identified. The findings of this thesis enhance our understanding of the molecular signature of tumour endothelial cells and lay the foundation for the potential development of novel anti-cancer therapies.


There is presently broad consensus that involuntary sterilization of an incompetent patient should be done only in the following unusual circumstances, and then only after approval by a court:
 1. If the progeny would be so severely damaged that their lives would be arguably worse than nonexistence (eg, a disorder such as Lesch-Nyhan syndrome), OR a retarded female's physical or psychologic health would be seriously jeopardized by a pregnancy and/or abortion (eg, severe heart or lung disease), AND
 2. There are no alternative, less restrictive ways of avoiding pregnancy (such as segregation, supervision, behavior control, or reversible forms of contraception), AND
 3. There has been a court order, following a process designed to ensure that the procedure is necessary to protect the interests of the patient.


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	    </jats:inline-formula> be a discrete group, and let <jats:inline-formula>
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This analysis utilizes the complex stress function approach to obtain the stress distribution in pin loaded composite joints with elliptic openings. The stress functions were derived from assumed displacement expressions that satisfy the boundary conditions around the hole. In the method of solution Coulomb friction was used to determine the prescribed displacements at the boundary. The material properties of graphite/epoxy and carbon fiber reinforced plastics laminates were used in this investigation and the results also compared with available data for joints with circular openings. It was revealed that the stress distributions followed the same pattern in both geometries but with lower magnitude in elliptical shape and the reduction in stress distributions caused by changing the pin/hole shape from circular to elliptic depend on friction.Copyright © 2010 by ASME


In this article, the authors explore how the social dynamics in a reading and writing event influence "who children are" (e.g., good readers, non-readers, leaders). The authors explore how the presence of English language learners (ELL) affects the distribution of symbolic capital (i.e., who has high status and prestige) in classroom social interaction, thus affecting the social identities available to the participants. The authors look beyond cultural and linguistic mismatch as reasons for which ELL students are often marginalized during literacy events. They argue that the issue lies in addressing the status that ELL students often have within the classroom community in relation to their non-ELL peers.


Since the starting of reform, China's industrial structure has experienced from unbalance to balance and then back to unbalance. In the late 1990s, the industrial structure even degenerated. The reasons for the unbalanced industrial structure are multi-aspects, and it is characterized by the transitional economy. At the present time, deepening the reform is the basic choice for solving the problems, but to deal with the relationship between administration and the enterprises is the urgent task.


The FPS Honorary Secretary represented both the FPS and the British National Appeal of WWF at the meetings of the International Whaling Commission, in Canberra, Australia, in June 1977. The FPS Statement to the IWC called again for a moratorium on whaling, as proposed at Stockholm in 1972, and commented: 'It is a sobering thought to consider how much larger the whale stocks and quotas were in 1972 than they are today'.


Purpose : Thyroid hormone is essential for development of the brain in early life. Thyroid dysfunction is more common in the first 2-4 postnatal weeks of life in premature infants than in term infants. This study aimed to identify the prevalence and clinical course of thyroid dysfunction in prematurity. Methods : Premature infants admitted to and given neonatal screenings at Dankook University Hospital between April 1999 and March 2008 were included in this study. We retrospectively reviewed medical records and categorized subjects into six groups: normal, hypothyroidism, hyperthyrotropinemia, hypothyroxinemia, delayed onset of hypothyroidism, and delayed onset of hyperthyrotropinemia. Results : Among 599 subjects, 136 (23%) had initially abnormal thyroid function test (TFT); transient hypothyroxinemia was the most frequent condition (118, 20%). In addition, 8 (17%) of 46 subjects with initially normal TFT levels showed delayed onset of hyperthyrotropinemia with or without low free thyroxine (fT4). Thyroxine was prescribed for 10 patients (1.7%) due to low fT4 levels but was discontinued in 9 patients during follow-up. Thyroid scan confirmed ectopic thyroid in one patient. Conclusion : Thyroid dysfunction was frequently seen in premature infants, but most of the conditions were transient. In addition, some infants showed delayed TSH elevation on routine follow-up. Therefore, a recheck of the thyroid function of premature infants at 3-4 weeks is recommended, even if normal thyroid function is initially seen, especially in prematurity of less than 33 weeks of gestational age or birth weight of less than 2,500 grams.


Human activity in ecosystems has become very significant. The article establishes a set of factors that pose a danger to the health of the population. The analysis of the incidence in the region was made. The conducted studies show that the medico-ecological situation in the Orel region remains tense.


— The purpose of this research is to investigate the possible correlation between quality tools and innovation generation in companies nowadays, with particular interest in the financial sector, governed by strong regulation. Quality Management is one of the main axes of modern management, a movement that had its peak in the '80s and '90s. Due to the high competitiveness of markets and the increasing use of technologies in the development of new businesses and products, innovation and quality have become concerns of the organizations that aim to obtain a sustainable competitive edge. In this way, a bibliographic review allied to the case study was conducted in the retail banking industry, followed by comparative analysis in order to deepen the interpretation of the


There are many ways an organization can approach innovation. On one end of the spectrum an organization can choose to have everyone submit any idea. On the other, innovation can be generated from a small, dedicated group of specialists. In the middle there are many variations along the way. This paper discusses the open innovation typology and the options for an organization making the decision about the best way to create an innovation infrastructure.


The solution to the operation effect assessment system of weather modification based on statistical test is presented in this paper after studying the theory of statistical test and regression analysis.Its prototype system is implemented as well.The prototype system uses C/S(client/server) architecture,integrates the technologies of.Net framework,TCP/IP protocol,multi-threading,database connection pool and large database,etc.,effectively solves the correlated problems of massive meteorological data classification and inputting to special database,and implements the comprehensive assessment on operation effect based on multi-index of rainfall and temperature materials.The system has high assessment efficiency with satisfactory fault tolerance.


According to the actual situation of the power plant project,at the same time,combined with,the bartender electric PCS-996-PMU the function of synchronous phasor measurement device,This paper puts forward the design of synchronous phasor measurement system in power plant and substation configuration and application.


Neuroendocrine carcinoma of the large intestine and rectum is an uncommon type of neuroendocrine tumor (NET) that accounts for <1% of all colorectal cancer [1].The incidence of NETs of the colon and rectum has been increasing in the past decades, thought due in part to increased screening colonoscopies. Although still uncommon, with an estimated incidence of 0.3 and 1.1 per 100,000 in developed nations [2]. The clinical development of NET of the colon includes very destructive and aggressive growth, followed by rapid spread [1] and usually presents with non-specific symptoms, most commonly bleeding, abdominal pain, change in bowel habits, anorexia, weight loss, and weakness [3]. These non-specific manifestations are frequently misdiagnosed, causing a delay in diagnosis and decreasing the chances to perform a successful surgical treatment. 2. CASE REPORT


Three kinds of electrostatic modes are experimentally observed to propagate along magnetic‐field lines in a pair‐ion plasma consisting of only positive and negative fullerene ions with an equal mass. It is found that the phase lag between the density fluctuations of positive and negative ions is fixed at 0 and π for ion acoustic and ion plasma waves, respectively. In addition, a backward‐like new mode appears in an intermediate‐frequency band between the frequency ranges of the two waves, the phase lag of which strongly depends on the frequency.


A new low voltage low power fully differential CMOS four-quadrant analog multiplier based on the operation of MOS transistors in saturation region is given. The proposed four-quadrant voltage-mode multiplier was confirmed by using PSPICE simulation and 0.25µm CMOS technology and found to have good linearity with wide input dynamic range. The static power consumption is 0.326 mW, the input voltage range is ±0.75 V from ±1V supply, the bandwidth is 16MHz at 1KΩ//10pF load, the output referred noise voltage is less than 10 nV/√Hz in 1KΩ, and the maximum linearity error is less than 1 % at ±0.5 V input voltage.


People who have near-death experiences (NDEs) often report a subsequently increased sense of spirituality and a connection with their inner self and the world around them. In this study, we examined daily spiritual experiences, using Underwood and Teresi's (2002) Daily Spiritual Experience Scale, among 229 persons who had come close to death. Frequency of daily spiritual experiences before the close brush with death did not differentiate participants who had NDEs (n 204) from those who did not (n 25). However, participants who described having had NDEs reported more daily spiritual experiences after their brush with death than those who did not, and frequency of daily spiritual experiences after the brush with death was positively correlated with depth of NDE. We discussed the implications of these findings in light of other reported aftereffects of NDEs and of daily spiritual experiences among other populations.


From the aspects of objective factor and subjective factor,the paper analyzed main problems existing in process of construction contract management. Then it discussed the countermeasures and put forward preliminary opinions for improving contract management of construction projects.


This paper deals with the seismic analysis of timber framed houses filled by stones and earth mortar using a multi-scale approach going from the cell to the wall and then to the house. At the scale of the elementary cells, experimental results allow fitting the parameters of a new versatile hysteretic law presented herein through the definition of a macro-element. Then, at the scale of wall, the numerical simulations are able to predict its behavior under quasi-static cyclic loading and is compared to experimental results allowing validating the macro-element model.


In this paper we consider the motion of a particle in a linear array of fluctuating barriers. Each barrier can be closed or open and fluctuates in time. The motion of the particle is any stochastic motion between the barriers and the closed barriers stops the particle. We give several rigorous asymptotic results for the transmission probability of the particle and use them to show that this model presents a stochastic resonance with respect to the probability of finding a barrier closed.


With the application of Criminal Procedure Law(1996), the simplified trial of general procedure in criminal cases was put in practice in order to reveal the perusal of value of justice and efficiency in the judicial practice. But with the lack of lawyer's help to the accused and aid measures of judicial resources and weak justness with deficient legal bases, it needs more exploration in the practice.


Dementia disorders predispose for lethal complications and decrease life expectancy. A more profound knowledge regarding end‐stage conditions in dementia could therefore ameliorate treatment and care of these patients.


The social learning and social bonding theories of deviant behavior were investigated in four community contexts: farm, rural-nonfarm, suburban, and urban. The mean differences across these contexts on pertinant variables did not form a continuum from rural to urban. Rather, the farm and suburban areas were similar, and the rural-nonfarm and urban areas were more alike than either of the other two contexts. A number of the social bonding variables interacted with community context, but no systematic pattern was observed. Social learning variables did not interact with context. Rather, the different level of these variables appeared to account for the variance in deviant behavior.


Abstract In the asymptotic theory of interaction noise from contra-rotating propellers with many blades, previous work in the frequency domain has shown that, for each combination mode/tone, the critical points that dominate the acoustic radiation can be linked to two criteria (sonic and normal-edge) and to a radial event line that spins around the annulus at the same speed as the mode. Thus the speed is different for each combination tone. In real time, however, the interactions precess around the annulus at a single speed, governed by the 'firing order' of the interactions, with that speed being (in general) considerably different from that of either the front or rear blade rows. The precession of the interaction is described here in detail and then demonstrated by application to three relevant architectures, including a rotor–stator configuration. The paper then considers how the blade leading-edge design affects the radial variation in the interaction location and analyses the interactions from the viewpoint of a far-field observer. The paper also connects previous time- and frequency-domain results by showing that the sonic and normal-edge criteria can be derived in the time domain using the precession speed. The case of equal blade numbers is also included, for which the precession speed becomes infinite but for which, nonetheless, the sonic and normal-edge criteria still apply.


The theme of our paper approaches the particular aspects of the educational, research and production environment, from a multi-dimensional perspective: the contents of the educational process; the modernizing of the didactic technologies by integrating the informational and communication technologies and using the educational potential of mass-media; the universities' role in research and in forming future researchers; the role of pre-university education in this context. Finally, the paper performs a case study achieved at the Faculty of Materials Engineering, Mechatronics and Robotics from Valahia University from Targoviste. The subjects chosen have been the students from the Faculty of Materials, Equipments, Installations, Mechatronics and Robotics of all study years from major field of study.


The aim of this study is to investigate the relationship between transformational leadership and balanced scorecard of academic leadership at the University of the South Valley, Egypt. The number of academic leaders (n = 131) as a statistical sample of this study. In order to collect the data from balanced scorecard questionnaire that assesses 5 micro scales been prepared, and multifactor leadership questionnaire (MLQ), (Bass and Avolio, 1994) measured 4 micro scales relating to transformational leadership. The results showed that there is a significant relationship between transformational leadership and balanced scorecard. The correlation of the total score transformational leadership and balanced scorecard indicated a positive, linear relationship (r= 0.50). Thus, it is important to understand the characteristics of leadership toward balanced scorecard since it will affect the Performance evaluation of University.


One of the major focuses of current research is to develop new schemes which can be used to maximize multi-access communication system capacity and increase user bandwidth utilization efficiency. To maximize system capacity and bandwidth utilization efficiency for multiuser and UWB communication systems, a set of mutually orthogonal waveforms with low correlations and prescribed spectral properties are highly desirable. Recent release of spectral mask for UWB communications has further highlighted the need for a new systematic approach to design waveforms with maximum transmitted energy while satisfying the mask constraints. In this thesis the design of analogue waveform sets based on suitably chosen Hermite Rodriguez basis functions is investigated. The Hermite Rodriguez functions have been recently applied and proven to be useful in other areas such as radar, biomedical and image processing applications. First, analogue waveform set design is formulated as a constrained nonlinear optimization problem to minimize stopband energy and shape the magnitude spectral functions to a fixed desired spectral shape. To minimize interferences in multiuser systems, autocorrelation and crosscorrelation constraints are incorporated into the optimization problem. The optimization problem is solved sequentially with the crosscorrelation constraints treated as linear inequality constraints. The proposed approach provides a new alternative to design signature waveforms and proves the suitability of the Hermite Rodriguez basis functions to design signals with finite time support. Next, a sequential quadratic semi-infinite programming approach is proposed to design a set of spectrally efficient orthogonal UWB waveforms. Nonlinear spectral and crosscorrelation constraints formulated into the optimization problem are linearized respectively by using the real rotation theorem and by solving the quadratic semi-infinite program sequentially. Since recently released spectral mask limits the power spectral density (PSD) of a UWB waveform to a very low level, it is of a paramount importance for the UWB waveforms to have maximum energy while satisfying the given spectrum mask constraint. The proposed approach therefore directly maximizes the energy of transmitted waveforms with no phase angle constraints imposed on the waveforms. The proposed approach produces high number of waveforms with high spectral efficiency. The flexibility of the proposed approach to suppress multiple narrowband interferences at multiple frequencies is further demonstrated through a numerical example. Then, the spectral efficiency of the designed waveform is further improved by incorporating the power spectral density of a commonly used basic pulse into the design problem formulated as a semi-infinite quadratic optimization problem. The resulting nonlinear piece-wise continuous bounds are converted into linear constraints using the real rotation theorem. The objective function is formulated as direct maximization of a quadratic function of filter coefficients which eliminates the spectral factorization step commonly used in FIR filter design via semi-definite programming. Optimal upper bounds for each basic pulse are implemented as constraints in the optimization problem and therefore high spectral utilization is achieved especially when a suboptimal basic pulse is used. Finally, Löwdin orthogonalization method is used in this research to generate an orthogonal set of spectrally efficient waveforms from a finite set of equally spaced shifts of an optimal waveform. The optimal waveform is designed based on Hermite Rodriguez basis functions via a semi-infinite quadratic programming approach. The Löwdin method generates a set of overlapping waveforms with minimal energy distortion with respect to the optimal waveform. This set of undistorted overlapping waveforms is desirable for orthogonal overlapping pulse position modulation (PPM) UWB systems. A numerical example is presented to illustrate the ability of this 2-step approach to produce many overlapping orthogonal waveforms while complying with the FCC spectral mask.


Background: Myocardial and arterial load are time-varying phenomena. Despite its importance in myocardial biology and function, the arterial properties that determine time-resolved myocardial wall stress have not been directly investigated. Methods: We studied 1215 adults enrolled in the population-based Asklepios study. Time-resolved central pressure and flow were measured with carotid tonometry and Doppler echocardiography. Time-resolved short- and long-axis LV geometry was measured with speckle tracking echocardiography. Using custom-designed software, we computed arterial load, circumferential (CWS) and longitudinal (LWS) wall stress (Regen method) using time-resolved measurements. Results: For any given end-diastolic LV cavity size and wall thickness and any given cardiac output, peak CWS correlated directly with systemic vascular resistance (SVR; Beta weight=1.07; P Conclusions: Different arterial properties have selective effects on time-resolved myocardial wall stress which are not apparent from single-time-point measurements. Women appear to demonstrate less efficient myocardial-ventricular-arterial coupling (higher time-varying stress for a given output) independently of various arterial properties and end-diastolic LV geometry. These observations could provide insight into the well known differential susceptibility of women to heart failure with preserved ejection fraction.


From our previous data that static exercise produced a significant decrease in the renal blood flow (RA), it was hypothesized that the blood flow in RA also decreases during dynamic exercise with graded workloads. Nine healthy female volunteers participated in the present study. After 10-min resting, the subject performed a 15-min bicycling exercise consisting of three workloads of 30%, 50%, and 70% of peak oxygen uptake ( O2peak) for 5 min for each workload. During dynamic exercise, the responses in oxygen uptake, minute ventilation, mean arterial blood pressure (MAP), cardiac output, and heart rate increased linearly with three workloads from rest to 30%, 50%, to 70% of O2peak. However, the mean RA velocity (MVB), measured by ultrasonography, showed a linear decrease with the workloads. The index of vascular resistance in RA (RVR), calculated as MAP RA velocity, showed a significant increase from resting level during exercise at 50% and 70% of O2peak. There was a significant increase in RVR from 50% to 70% of O2peak. The present data supported the hypothesis that the graded bicycling exercise produces a significant increase in the renal vascular resistance over the workload of 50% O2peak.


This Special Issue presents 17 papers selected from 11th International Conference on Computational Heat and Mass Transfer (ICCHMT2018). The conference was held in Cracow, Poland, 21–24 May 2018. Th...


Background: Being a spring holiday, Navruz is one of the vibrant and colorful folk festivities, which came down to use from time immemorial. In different forms and under various names it is celebrated by almost all nations and people of the East. Navruz holiday symbolizes renewal and the wakening of nature. Since 1992 Uzbekistan has been celebrating Navruz annually. It was inscribed on the UNESCO Representative List of Intangible Cultural Heritage of Humanity (2009) as a multinational nomination (Azerbaijan, India, Iran, Kyrgyz Republic, Pakistan, Turkey and Uzbekistan). 21 March is considered as International Day of Navruz and celebrated internationally since 2010.


Advancing age is a severe risk for cancer in both sexes: the risk is 8%-9% in patients 40-59 years of age compared with 20%-30% at ages > 60 years. According to Surveillance, Epidemiology and End Results data, nearly 60% of all newly diagnosed malignant tumors and 70% of all cancer deaths are in persons ≥ 65 years of age, and the number is expected to increase. Lung cancer is the second most common cancer and leading cause of cancer death among men and women, and its incidence increases with age. 1 Carcinogenesis is linked to progressive damage to DNA. It is related to cumulative exposure to exogenous carcinogens and age-related decreases in host defenses associated with decreased protection against oxidative damage and decreased immune defenses. Increased cancer incidence and mortality in elderly patients compared with adults ≤ 65 years of age has been attributed to host factors. Aging may impact chemotherapy effectiveness and toxicity. Decreased effectiveness of chemotherapy is thought to result from increased expression of the multidrug resistance gene, decreased apoptosis, tumor anoxia, and tumor indolence. Elderly patients have more indolent breast and non–small-cell lung cancer (NSCLC), shorter duration of remission in non-Hodgkin's lymphoma, and resistance to chemotherapy in acute myelogenous leukemia. Increased toxicity, conversely, may be related to pharmacokinetic changes in elderly patients caused by decreased volume of distribution, decreased glomerular filtration rate, and decreased hepatic metabolism.


Dropout rate is an important indicator of the quality of higher education systems, especially in the case of mass education. When the Bologna reform in higher education was introduced, it was hoped that more people would graduate from short-cycle undergraduate courses, but the transition from a more traditional educational model to the Bologna system did not reduce the dropout rates. In Romania, a recent study carried out by UEFISCDI indicates that almost half of the students enrolled in undergraduate programmes in 2015 had not completed their studies by 2021, while Herțeliu et al. (2022) show that 43.8% of students drop out of university while being enrolled in the first year of a bachelor's degree programme. The current study focuses on two surverys carried out at a Romanian higher education institution (Babeș-Bolyai University), with the aim of identifying individual, socio-demographic and institutional risk factors for university dropout, as well as factors that protect against it. Using factorial analysis, the study reveals that the factors associated with university dropout have a multi-causal character, and are related to both institutional, economic and external factors.


The field of business policy and strategy has evolved and changed over the past 30 years. The accumulation of a body of scholarly work based on empirical and theoretical investigation, the shift in the type of student, and a transformation of the business arena through technological and global forces have all changed the context of the course. As a consequence, sole reliance on the traditional case method is no longer sufficient. Instead, multiple methods that encourage participation, critical thinking, communication, integration, and the translation of theory to practice are necessary. This article suggests that an assessment of the congruence of the outcomes of different methods with the stated goals of the course should be a crucial factor in the choice of pedagogical tools.


Through the research and analysis of the common quality problem in the concrete road,the author analyzes the cause of the common quality defects in the concrete road surface from the aspects of the crack,the sugaring,the honeycomb and scale and the embossing,and puts forward the solution to guarantee the safety and comfort of the driving traffic in the districts.


ABSTRACT The petrology of gravels from a spit in the lee of the former island of Urk is discussed. The composition shows the gravels to have been derived from glacial till. The relations of roundness to distance of transport and of shape to vertical position on the spit are analyzed. Two principal methods of evaluating roundness and shape, those of Wadell-Krumbein and of Cailleux are compared theoretically and in relation to their results.


Upconversion of sub-bandgap photons is a promising approach to exceed the Shockley-Queisser limit in solar technologies. Calculations have indicated that ideal, upconverter-enhanced cell efficiencies can exceed 44% for non-concentrated sunlight, but such improvements have yet to be observed experimentally. To explain this discrepancy, we develop a thermodynamic model of an upconverter-cell considering a highly realistic narrow-band, non-unity-quantum-yield upconverter. As expected, solar cell efficiencies increase with increasing upconverter bandwidth and quantum yield, with maximum efficiency enhancements found for near-infrared upconverter absorption bands. Our model indicates that existing bimolecular and lanthanide-based upconverters will not improve cell efficiencies more than 1%, consistent with recent experiments. However, our calculations show that these upconverters can significantly increase cell efficiencies from 28% to over 34% with improved quantum yield, despite their narrow bandwidths. Our results highlight the interplay of absorption and quantum yield in upconversion, and provide a platform for optimizing future solar upconverter designs.


See also Zafrani L, Mariotte E, Darmon M, Canet E, Merceron S, Boutboul D, Veyradier A, Galicier L, Azoulay E. Acute renal failure is prevalent in patients with thrombotic thrombocytopenic purpura associated with low plasma ADAMTS13 activity. J Thromb Haemost 2015; 13: 380-9 and Zafrani L, Azoulay E. Acute renal failure is prevalent in patients with thrombotic thrombocytopenic purpura associated with low plasma ADAMTS13 activity: reply. This issue, pp 1526–7.


Aim. To study the prevalence of hyporesponse to statin therapy and its impact on the development of heart failure (HF) among patients after acute coronary syndrome (ACS) in a short-term follow-up.Material and methods. This retrospective analysis of outpatient medical records of 400 patients observed at the Omsk Clinical Cardiology Dispensary after ACS was carried out. Optimal medication therapy was prescribed as part of the preferential provision of medicines under the 1H Program, including high-dose atorvastatin therapy (80 mg/day). Low-density lipoprotein cholesterol (LDL-C) was assessed at baseline and 1 and 12 months after therapy. Hyporesponse to statins was defined as the percentage reduction in LDL-C 14; left atrial volume index >34 ml/m2) function.Results. There were 107 patients with hyporesponse (26,8%). Depending on the initial response to therapy, patients were divided into two groups: group 1 (hyporesponse, n=107), group 2 (more pronounced response, n=293). After 1 month, patients in the hyporesponse group had a higher level of LDL-C — 2,4 [2,2; 2,9] mmol/l (Me [25; 75%]) vs 2,0 [1,7; 2,5] mmol/l (p>0,05) in the second group. There was no difference in the prevalence of hospitalizations for recurrent ACS in the compared groups, as well as in the prevalence of new HF cases between groups.Conclusion. The prevalence of hyporesponse to statin therapy was 26,8%, which required correction of lipid-lowering therapy in order to prevent recurrent cardiovascular events. Given the pleiotropic effects of statins that can participate in HF pathogenesis, as well as the inconsistency of current research results, further prospective long-term studies are required.


Background: Advancement of health care was salient which resulted in more people living longer with complex medical conditions seeking dental care. Objective: To assess the medical profile of patients attending primary dental care clinics in the College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Methods medical records of 312 adult female patients who presented to primary care clinic and filled the standardized medical questionnaire in the period from 9th of July to 9th of August 2017 were randomly selected and reviewed. Collection of data was done which included demographic data, chief complaint, medications, and current medical condition Results: The age group ranged from 18 to 77 years old, (28%) of patients have at least one medical condition, and 22.44% of patients are taking medications. The most common medical condition was anemia (11.9%) followed by short of breath (6.1%), chest pain and diabetes mellitus (DM) (5.4%), hepatitis (3.8%), ankle swelling (3.5%), bleeding disorder (2.6%), asthma and arthritis (2.2%), heart trouble (1.0%), Rheumatic arthritis, Kidney trouble, Hepatitis and Cancer (0.3%). Age category (forty-six to fifty-five years old) had the highest rate of medical problems 75% Conclusion: Results showed that approximately one-quarter of patients attending the primary dental clinics have a medical problem. It is important that dental practitioners be knowledgeable about the proper management of patients with medical problems. Further studies are recommended to extend the study period.


The final degree project presents a study about diferents aspects of an indoor hydroponic system, carried out in collaboration with InstaGreen S.L. company, located in the city of Barcelona. The main objective is to improve the growing facilities in order to guarantee the optimization of the material and economic resources, without losing sight of the ecological and local attributes of the company, which increase the value of the final product. In this project different tests were conducted on: germination seeds, light, water and other aspects that turned out to be relevant to the production.


The use of concentrated hydrogen peroxide as an agent which etches TiW is well known in the metals industry. Although hydrogen peroxide is used in most semiconductor manufacturing processes, its' application as an etchant for TiW has been limited. Since some Micro-Rel product uses a composite metallization scheme containing a TiW/AlSiCu/TiW sandwich, the bonding pad etch process must include a TiW removal step. Without this step, a residual TiW layer is left on the metal pads causing wire adhesion problems (non-sticks) during the wire bonding processes. Current plasma etch techniques still leave a TiW residue on the aluminum surface. The hydrogen peroxide clean was instituted to minimize the presence of the TiW residue. By inserting this clean as the last step of the pad masking module, a cleaner metal surface was developed. To test the new process, wire pulls were done on product by two separate business units within Medtronic. Results from both areas showed no lifts. Surface analyses of metal bond pads treated with hydrogen peroxide shows a significant decrease in the concentrations of metallic oxides and tungsten. The SEM images of bonding pads show no loss in metal thickness and the metal surface is relative smooth with no trace of TiW visually evident.


The car designed under the embedded control can realize the actions such as forward,backward,left turn and right turn,and can change its motion states of cross country in the walking process with sound control.This article also introduced the hardware,software and general design scheme of the car.


In this paper,the history of the development of sonochemistry and the principle of action are simple stated.At the same time, the application of sonochemistry to accelerating chemical reaction is preliminarily studied.


The Fifth Generation (5G) of network has great advancement from other network evolutions in terms of features, flexibility, high-speed internet, quick communication, and the capacity to connect to new enterprises. However, setting up the infrastructure for the 5G network requires more cell towers and higher frequencies such as 6GHz to 100GHz and millimeter waves (MMW), which results in increased radiation emissions. This article explains the methods that have been discovered as well as some new, innovative approaches to the radiation reduction findings. This study measures the radiation based on the parameters like overall power consumption, radiation frequency and the consequences of exposure. The studies that are now available is not offering enough data to make a thorough safety evaluation of thermal impact. This study performs more investigation and study to reveal the additional aspects, including millimeter wave, mobile edge computing, a variety of antenna technology, machine learning, radioactivity, radiation types, and radiation effects. The main purpose of this research study is to highlight the recent researcher advancements in the 5G mobile system, gadgets, and radiation effects, as well as future research goals.


Samples of Culicoides midges were caught each month for I I months at the veterinary research farm near Harare. The insects were most abundant in the wet season and the spring. Akabane, Nyabira, African horsesickness, blue tong and Ephemeral fever viruses were isolated from various Culicoides midges.


Flange for lift guides, comprising: # - a base (2), which is a metal slimline-protuberance plate with at least one (2a) on which supports one side of the wing of the guide; and # - a rim (3), which is a metal sheet folded in the "Z" in one wing of which (31) has at least one projection-inlay (3a) on which supports the opposite side of the guide and whose web (32) are arranged one or more projections-stop (3b) on which rests the flange edge guide. # arranging base (2) and rim (3) means for positioning without mutual rotation together.


Mobile edge computing (MEC) is currently one of the key technologies that can facilitate the evolution of the future digitized economy. MEC can provide ubiquitous computational capabilities through the multitier deployment of servers to ensure lower latencies and tighter integration with 5G, the Internet of Things, blockchains and artificial intelligence. In this paper, we propose a new approach to optimizing hardware resource allocation for edge nodes in a multitier MEC hierarchy. In addition to a centralized unit, we consider active antenna units and distributed units equipped with edge nodes of different computational capacities. A parametric Bayesian optimizer is implemented for hardware resource allocation to increase the overall computational capacity of a 5G-based MEC system. Simulation results show that for given budget constraints, the proposed solution outperforms pseudorandom resource allocation in terms of the proportion of computational tasks completed. The achievable gains are in the range of 20-40 %, depending on the task complexity and selected budget threshold.


In this paper, a mathematical model was developed to describe the dynamic behavior of a bioreactor in which a fermentation process takes place. The analysis took into account the bioreactor temperature controlled by the refrigerant fluid flow through the reactor jacket. An optimal LQR control acting in the water flow through a jacket was used in order to maintain the reactor temperature during the process. For the control design, a reduced-order model of the system was considered. Given the heat transfer asymmetry observed in reactors, a model considering the fractional order heat exchange between the reactor and the jacket using the Riemann–Liouville differential operators was proposed. The numerical simulation demonstrated that the proposed control was efficient in maintaining the temperature at the desired levels and was robust for disturbances in the inlet temperature reactor. Additionally, the proposed control proved to be easy to apply in real life, bypassing the singularity problem and the difficulty of initial conditions for real applications that can be observed when considering Riemann–Liouville differential operators.


H istorically, many professionals in blood banking and transfusion medicine did not have any special interest or expertise in blood coagulation. Other areas of emphasis, such as serology, apheresis, or infectious disease, were much more common. However, we hope that we can convince our readers that gaining more background in coagulation has the potential to improve transfusion practice and patient care.


THE ROLE OF CORRELATIONS OF BASIC COMPONENTS OF PEDAGOGICAL MASTERSHIP IN THE SYSTEM OF TRAINING SPORTS PERSONNEL A.A. Manoylov, Ph.D. Velikie Luki state academy of physical culture and sport, Velikie Luki Key words: training of sports personnel, individual-psychological features, pedagogical direction, vocational competence. The purpose of the research was to study the role of correlations of basic components of pedagogical mastership in the system of training sports personnel. Methods and organization of the research. For more precise assessment of aptitude of students for this or that vocational activity in the sphere of physical culture and sport there was applied test-questionnaire of R.Kettel, allocating the level of expression of psychological personal features. 72 -5-year students of all pedagogical specialities of Velikie Luki state academy of physical culture and sport were tested using this technique. The results were analyzed by three constituents: intelligence, communicative and emotional-volitional abilities. Based on the received data there was constructed a profile of personal features and psychological characteristics of student of high school of physical culture. The studies proved that the presence in a future specialist of necessary personal individual-psychological features and its correlation with basic components of pedagogical mastership resulted in success in vocational training and further pedagogical activity. Personal factor determines direction of vocational activity, its strategy, qualitative aspect of education- competence. Thus psychological monitoring is necessary while entering high school with further analysis and forecast of vocational perspectives. Later on it can serve as a basis of differentiated approach to technology of formation of vocational mastership and direction of activity.


It is a cutting machine for cutting metal indicated that a substructure, the rail (8), a driving support (2), a passive support (3), a cross-beam (1), a transverse drive device (4), a conveyor (6) , a tow chain (9), a rail cleaning device (11), a cutting torch support (10) and a control system comprises, based on a software program. The rails (8) which have a circular cross-section, each mounted on the substructure parallel and the drive support (2) and the passive support (3) move synchronously to each other on the rail (8). Means (7) for automatic adjustment in the transverse direction and in perpendicular thereto oriented, the longitudinal direction is provided on the drive support (2) and at one end of the drawn cross-beam (1) and the passive support (3) is connected to the other end of the cross-beam (1) fixedly connected. Longitudinal drive means (5) are symmetrical at lower parts of the drive support (2) and the passive support (3) is mounted. The longitudinal drive means (5) comprise a rack and pinion and guide means for the distance between the toothed rack and the gear setting by resilient sliding. The cutting machine according to the invention has a compact structure and can be operated continuously and reliably.


The purpose of this paper is to summarize in some detail the application of prestressed concrete to coastal structures, explain the basic theories of prestressed concrete, and give an explanation of an application of prestressed concrete recently designed and used by the author.


Having received the special report of the United Nations Command of 18 October 1952 on 'the present status of military action and armistice negotiations in Korea' and other relevant reports relating to Korea, Noting with approval the considerable progress towards an armistice made by negotiation at Panmunjom and the tentative agreements to end the fighting in Korea and to reach a settlement of the Korean question,


The rapid development of express delivery industry has consumed a lot of social energy resources. Improving energy efficiency is the most rapid, feasible and effective way for express delivery industry to solve the energy issues. Based on the theories about the Internet of Things and Energy Informatics, this paper puts forward new ideas to improve energy efficiency of express delivery industry, builds the framework of the Internet of Things for express delivery industry, in hope of building a bridge to connect physical world, information world and energy efficiency. Moreover, this paper also makes an analysis of specific strategies to improve energy efficiency of express delivery industry with the help of the Internet of Things.


During the later part of the 20th century the amount of children and adolescents in Sweden who reported psychosomatic illness have greatly increased. The main reason is estimated to relate to weak ...


This brief paper seeks to assess the possibility of an ethic in Descartes' philosophy, beyond the reduced epistemological vision of the scientific researcher. Rene Descartes is approached outside the concise and cold rationalism; the author of this contribution seeks a view of the world and being-in-the-world closer to the problem of existence in his theoretical work and philosophy, both rich in interpretations. Its main postulates are thus challenged by ethics, extracting from them the implicit idea of self-care.


This paper presents a sampling rate digital down converter that is totally based on frequency domain processing. The proposed DDC is targeted for Software Defined Radio and Cognitive Radio architectures. The proposed architecture is based on replacement of the complex multiplication with direct rotation of the spectrum. Different aspects of frequency domain filtering are also discussed. The Xilinx Virtex-6 family FPGA, XC6VLX240T is used for the implementation and synthesis of the proposed FFT-IFFT based architecture. The overlapping in time domain at the output of the IFFT block is avoided using overlap and add method. In terms area, highly optimized implementation is observed in the proposed architecture when compared to the conventional DDC. The synthesis results have shown that the developed core works at a maximum clock rate of 250 MHz and at the same time occupies only 10% of the slices of FPGA.