We present the Bio-Matched Horn antenna: a novel 1.773 cm3 on-body antenna for very low-loss communication with wireless implants across the 1–9 GHz bandwidth. To achieve this unique performance, the Bio-Matched Horn is composed of water-filled holes used to mimic the frequency-dependent permittivity of the underlying tissue over its entire bandwidth. The horn shape further allows the proposed antenna to communicate efficiently through the biological tissue for both subcutaneous and deep-tissue wireless implants. Measurement results at 2.4 GHz are in good agreement with simulations and show a transmission loss of 8.01 dB to a 4 mm-deep implant and 19.21 dB to a 2 cm-deep implant. Compared to the previous designs, this is a remarkable improvement by 14.5 and 10.8 dB for subcutaneous and deep-tissue communication, respectively. In this paper, we discuss the operation principle and design of the Bio-Matched Horn, its performance for subcutaneous and deep-tissue implant telemetry, sensitivity to rotational and positional misalignments, and specific absorption rate performance.


The library of the University of Louvain's Faculty of Medicine has designed a programme that automates interlibrary loan requests between libraries: 'TELEDOC'. Once the orders have been typed in by the user, TELEDOC consults the BIOMED Union catalogue, selects a library that has the document and electronically mails the request to the selected library. Various complementary functions are also being developed.


In addition to the studies conducted regarding STEM (Science, Technology, Engineering and Mathematic), which is a new approach in education and attract attention worldwide, researches also concentrated on the effectiveness of the partnership of this interdisciplinary approach with other disciplines. The aim of this study is to determine the effect of an education carried out with an E-STEM activity on the environmental awareness of students and their opinions on E-STEM disciplines. In the study, a holistic multi-state pattern was used among the case study patterns. Data obtained from semi-structured interview and activity plans were analyzed using content analysis. There were 18 participants in the study conducted at a centralized public school in a province located in western Black Sea Region of Turkey, who were at 6th grade in the 2017-2018 Academic Year. The E-STEM activity prepared within the scope of the application was implemented for a total of 6 course hours for three weeks. At the end of the study, in the light of the information obtained from the participants who provide opinions on STEM disciplines, environmental awareness sub-dimensions and E-STEM, it was determined that the application had positive effects. Participants made positive statements about the environment, especially on recycling, and the use of the different disciplines together. Based on this research, it was suggested that it would be useful to develop studies on E-STEM.


Abstract This article presents a brief summary of a recent research investigation into the contribution of welfare members to processes of administrative review in Australia, and identifies a series of research and ethical issues which arose in the course of developing and implementing an appropriate methodology. The paper incorporates examples of how in this research methodological difficulties were resolved, and how the inevitable intrusions into the anticipated research landscape were managed.


Despite the demonstration of potent immunosuppressive function of T cell receptor (TCR)‐αβ+ double‐negative regulatory T cells (DN Tregs), scarce numbers and lack of effective expansion method limit their clinical applications. Here we describe an approach that allows for ∼3500‐fold ex‐vivo expansion of human DN Tregs within 3 weeks with > 97% purity. Ex‐vivo‐expanded DN Tregs suppress proliferation of polyclonally stimulated autologous T and B cells in vitro through direct cell‐to‐cell contact. In vivo, we demonstrate for the first time that infusion of human DN Tregs delayed an onset of xenogeneic graft‐versus‐host disease (GVHD) significantly in a humanized mouse model. Furthermore, preincubation of ex‐vivo‐expanded DN Tregs with a mechanistic target of rapamycin (mTOR) inhibitor rapamycin enhanced their immune regulatory function further. Taken together, this study demonstrates that human DN Tregs can be expanded ex vivo to therapeutic numbers. The expanded DN Tregs can suppress proliferation of T and B cells and attenuate GVHD, highlighting the potential clinical use of DN Tregs to mitigate GVHD.


Abstract Extracellular virulence factors have emerged as attractive targets in the current antimicrobial resistance crisis. The Gram‐negative pathogen Pseudomonas aeruginosa secretes the virulence factor elastase B (LasB), which plays an important role in the infection process. Here, we report a sub‐micromolar, non‐peptidic, fragment‐like inhibitor of LasB discovered by careful visual inspection of structural data. Inspired by the natural LasB substrate, the original fragment was successfully merged and grown. The optimized inhibitor is accessible via simple chemistry and retained selectivity with a substantial improvement in activity, which can be rationalized by the crystal structure of LasB in complex with the inhibitor. We also demonstrate an improved in vivo efficacy of the optimized hit in Galleria mellonella larvae, highlighting the significance of this class of compounds as promising drug candidates.


We have investigated the activated adsorption of methane on Pt(1 1 1) by the combination of a supersonic molecular beam and in situ high-resolution X-ray photoelectron spectroscopy at the German synchrotron radiation facility BESSY II. On exposing the surface to a methane beam with kinetic energies between 0.30 and 0.83 eV, CH3 is formed as a stable species at 120 K; upon heating, at around 260 K the adsorbed methyl partly dehydrogenates to CH and partly recombines to methane, which desorbs. Upon adsorption at 300 K, CH is directly formed as a stable surface species. To verify the chemical identity of CH as an intermediate, we have also investigated the thermal evolution of a saturated ethylene layer. Upon heating, at ∼290 K partial ethylene desorption and the formation of ethylidyne is clearly observed in the spectra, as expected from the literature. From the binding energies and also from the vibrational signature of the C 1s spectra, an unequivocal assignment of the various surface species is possible. Measurements of the sticking coefficients of methane show that the saturation coverage at 120 K depends on the kinetic energy of the molecule; furthermore, the sticking coefficient for vibrationally excited molecules is strongly enhanced.


An experiment was conducted to determine the heavy metal pollution status of selected six ponds in Rajshahi City Corporation for a period of 7 months from June, 2008 to December, 2008. Among heavy metals the mean values of Cu, Mn, Zn, Fe and Pb varied from 0.05±0.02 (Pond-5) to 1.79±0.88 mg/l (Pond-4), 21.30±2.64 (Pond-6) to 76.57±30.90 mg/l (Pond-1), 0.08±0.02 (Pond-6) to 1.25±0.79 mg/l (Pond-4), 0.75±0.10 (Pond-3) to 1.87±0.53 mg/l (Pond-5) and 0.14±0.12 (Pond-6) to 4.92±1.66 mg/l (Pond-4) respectively. This study indicated that the Pond-2 covered by garbage, polythene and other wastes, Pond-3 and Pond-4 received industrial wastes were moderately polluted whereas the Pond-1 received City corporation wastes was less polluted. DOI: http://dx.doi.org/10.3329/jles.v7i0.20131 J. Life Earth Sci., Vol. 7: 115-117, 2012


This paper treats robust controller design for Affine Fuzzy Large-Scale Systems (AFLSS) composed of Takagi–Sugeno-Kang type fuzzy subsystems with offset terms, disturbances, uncertainties, and interconnections. Instead of fuzzy parallel distributed compensation, a decentralized nonlinear pseudo state-feedback is developed for each subsystem to stabilize the overall AFLSS. Using Lyapunov stability, sufficient conditions with low codem-putational effort and free gains are derived in terms of matrix inequalities. The proposed controller guarantees asymptotic stability, robust stabilization, and H 1 control performance of the AFLSS. A numerical example is given to illustrate the feasibility and effectiveness of the proposed approach.


Posture recognition plays an important role in three-dimensional virtual experiments, it means that to complete its specific function by a particular posture to control program in responding an action. In order to easy use and making the posture recognition more accurate, this article proposed the use of Kinect sensor to get articulation point information, through its the Euclidean distance and angle of the articular point to distinguish a particular posture. The results show that this method can get higher recognition rate, and expand action library at any time to meet the decision requirements of different postures. Its helpful to reuse software and improve the efficiency in the use of virtual experiment.


Gravitational particle production of spectator fields due to the expansion universe during the inflationary and reheating phases of the early universe is of particular interest in the context of dark matter, since it allows to constrain the properties of the dark candidate by comparing the density of particles produced with the observed dark matter abundance. In such processes, tachyonic instabilities arise as a consequence of the coupling to the curvature, greatly enhancing mode production. In this work, we consider a massive vector field that is coupled to the curvature scalar and the Ricci tensor only, and study its gravitational production through inflation and reheating. We show how the mechanism is more efficient than in the case of a non-minimally coupled scalar field, giving rise to larger abundances. Moreover, we analyze the importance of the coupling to the Ricci tensor, which increases tachyonic instabilities in the system, and constrain the mass of the dark particle and the values of the coupling constants by comparing the corresponding abundance with observations


Health promotion specialists increasingly recognize that to be effective in improving the health and quality of life of citizens, they must incorporate policy advocacy interventions as integral, if not priority, strategies. Policy advocacy, as currently viewed and practiced, has roots in the concepts of democracy and citizen participation. In modern political thought, democracy is embodied in the concepts of freedom, equality, and participation.' Participation is frequently equated with democracy, the implication being that the greater the participation in political decision making, the greater the democracy.2 2


Globalization and adoption of technology have a huge impact on human resource management (HRM). As a result, the human resource role has become more strategic. The logical question arises: Will the human resource (HR) practices be standardized? The research question of this paper is whether the HR policies adopted in the United Kingdom will also be implemented in Slovakia. The aim of this paper is to critically evaluate the divergence versus convergence debate applied on the case of Slovakia and the United Kingdom. Firstly, the impacts of technology on the HR role followed by the explanation of how technology changes HRM will be discussed. The theories of universalists vs. contextual paradigms, and cultural vs. institutional explanations will be introduced as they underpin the main hypothesis of the research. Secondly, convergence versus divergence debate will be briefly discussed followed by the analysis of the case study. Lastly, recommendations and conclusion based on evidence will be provided. The case study will be used as a research strategy and evidence from previous research will be compared and critically analyzed. The results show that there is no consensus on what exactly 'business partner' is and what strategic duties an HR manager should have. The Slovak HR policies lag behind the United Kingdom's human resource management. The impact of communist regime, different historical development and laws implemented in the two countries suggest divergence rather than convergence. However, findings suggest that there is a certain tendency towards the convergence between the United Kingdom's and Slovak human resource policies. Even though Slovakia uses different HR methods, human resource management is exposed to companies from abroad using highly efficient HR policies. Consequently, more sophisticated methods are implemented in Slovakia. The factors such as the European Union enlargement, globalization, impact of technology, and deregulation and foreign direct investment have a converging tendency. Lastly, Hofstede's framework suggests that there are significant cultural differences between the two countries. This should be taken into consideration when the standardized human resource policies are implemented.


The antineoplastic effect of paclitaxel is mainly related to its ability to bind the β subunit of tubulin, thus preventing tubulin chain depolarization and inducing apoptosis. The relevance of the Class I β‐tubulin characteristics have also been confirmed in the clinical setting where mutations of paclitaxel‐binding site of β‐tubulin Class I have been related to paclitaxel resistance in non small cell lung and ovarian cancers. In the present study, we verified the hypothesis of a relationship between molecular alterations of β‐tubulin Class I and paclitaxel sensitivity in a panel of breast cell lines with different drug IC50. The Class I β‐tubulin gene cDNA has been sequenced detecting heterozygous missense mutations (exon 1 and 4) only in MCF‐7 and SK‐BR‐3 lines. Furthermore, the expression (at both mRNA and protein level) of the different isotypes have been analyzed demonstrating an association between low cell sensitivity to paclitaxel and Class III β‐tubulin expression increasing. Antisense oligonucleotide (ODN) experiments confirmed that the inhibition of Class III β‐tubulin could at least partially increase paclitaxel‐chemosensitivity. The hypothesis of a relationship between β‐tubulin tumor expression and paclitaxel clinical response has been finally verified in a series of 92 advanced breast cancer patients treated with a first line paclitaxel‐based chemotherapy. Thirty‐five percent (95% CI: 45–31) of patients with high Class III β‐tubulin expression showed a disease progression vs. only 7% of patients with low expression (35% vs. 7%, p < 0.002). Our study suggests that Class III β‐tubulin tumor expression could be considered a predictive biomarker of paclitaxel‐clinical resistance for breast cancer patients. © 2007 Wiley‐Liss, Inc.


OpenCourseWare is an innovative and bold idea. It aims to support learning and teaching programme significantly. Learning material contained in an OCW provides learners an opportunity to gain knowledge beyond their routine classroom environments. These are in the digital form which can be accessed online, thus breaking the barriers of time and distance. Indian academics can play a significant role in creating OCW materials for the students to propagate the teaching and learning process diluting the limitations of traditional educational setup and begin a new culture of "Learning Beyond Classroom". The present study aims to sensitize the teachers and learners about the potentials of the OCWs. It presents a proposal for creating an "Indian OCW Consortium" at different levels. Also discusses the challenges and issues in establishing such an OCW project.


The authors present a way of performing the spring experiment that requires more personal involvement on the part of the student.(AIP)


To improve the efficiency of the electric power generation, monthly maximum electric power consumptions for a next one year should be forecasted in advance and used as the fundamental input to the yearly electric power-generating master plan, which has a greatly influence upon relevant sub-plans successively. In this paper, we analyze the past 22-year hourly maximum electric load data available from KEPCO(Korea Electric Power Corporation) and select necessary data from the raw data for our model in order to reflect more recent trends and seasonal components, which hopefully result in a better forecasting model in terms of forecasted errors. After analyzing the selected data, we recommend to KEPCO the Winters' multiplicative model with decomposition and exponential smoothing technique among many candidate forecasting models and provide forecasts for the electric power consumptions and their 95% confidence intervals up to December of 1999. It turns out that the relative errors of our forecasts over the twelve actual load data are ranged between 0.1% and 6.6% and that the average relative error is only 3.3%. These results indicate that our model, which was accepted as the first statistical forecasting model for monthly maximum power consumption, is very suitable to KEPCO.


We have studied the charged BTZ black holes in noncommutative spaces arising from two independent approaches. First, by using the Seiberg-Witten map followed by a dynamic choice of gauge in the Chern-Simons gauge theory. Second, by inducing the fuzziness in the mass and charge by a Lorentzian distribution function with the width being the same as the minimal length of the associated noncommutativity. In the first approach, we have found the existence of non-static and non-stationary BTZ black holes in noncommutative spaces for the first time in the literature, while the second approach facilitates us to introduce a proper bound on the noncommutative parameter so that the corresponding black hole becomes stable and physical. We have used a contemporary tunneling formalism to study the thermodynamics of the black holes arising from both of the approaches and analyze their behavior within the context. MSC: 81-XX Quantum theory 83-XX Relativity and gravitational theory


Here, we describe a new-freeze method (NFM) for rapid purification of PCR products. After PCR products were separated by horizontal common agarose electrophoresis, gel fragments containing the desired PCR products were directly subjected to NFM. The resulting gel was frozen in nitrogen canister for 60 s and thawed in 70°C for 2 min and then centrifuged. DNA in the supernatant was stored at -20°C until further use. PCR products in the size range of 100-2000 bp were purified within nearly 5 min. NFM could separate 2 DNA fragments that differed in length by 50 bp. As judged by the purification efficiency, the quality of PCR products separated by NFM was equal to that of the method of DNA purification by low-melting-agarose gel method (LMM) and freeze-squeeze method (FSM). NFM reduces the operational time and cost of recombinant DNA technology, in which purification of PCR products is a repetitive process. With no complicated equipment and technical training, NFM is very simple and easy to operate.


CASE REPORT On admission her general condition -was good; her temper2ture was 1020 F., pulse rate 120, and respirations 24. There was a well-marked scarlatiniform eruption on the body. The tongue was furred, the throat deeply injected but clean, and the cervical glands were slightly enlarged and tender. The heart, lungs, and abdomen appeared normal; the urine contained a faint trace of albumin. On November 4th her temperature was 1030 F., and 10 c.cm. of antistreptococcal serum were given intramuscularly. On November 7th the temperature ranged from 1040 to 1060, and the rash became more and more vivid; 20 c.cm. of antistreptococcal serum were injected intramuscularly. Diarrhoea began and albuminuria was still present, a few granular casts being found on microscopical examination of the urine. On the following day the Widal reaction was reported negative. On the 9th her temperature was 1030, the rash was still present, and coarse desquamation w-as beginning on the face and hands. A differential white cell count gave the following result: polymorphoniuclears, 61 per cent. ; small lymphocytes, 17.5 per cent. ; large lymphocytes, 3 per cent.; transitionals, 0.5 per cent. eosinophils, 18 per cent. There was thus a slight leucocytosis and a marked eosinophilia. On the 12th a blood culture was reported sterile, and examination of the faeces showed numerous streptococci but no pathogens. On the 17th the temperature became normal for the first time since admission. Slight abdominal tenderness was present and the diarrhoea was worse, the stools being fluid, with ;hreds of mucus and pus. On November 23rd the temperature rose again, ranging from 1000 to 1030. The patient was comatose by day and restless and noisy by night. There was generalized tremor, but examination of the central nervous system revealed nothing abnormal. Large pieces of skin were now desquamating off the hands and feet, and smaller pieces were being shed from the face, trunk, and scalp. There was no thickening or induration of the skin surface. The lips were involved in the general desquamation, but the buccal mucous membrane was unaffected. The eyebrows, eyelashes, and hair began tok fall out. On the 27th the general condition was much worse, the diarrhoea still persisted, and the patient collapsed and died at about 9 p.m.


This paper explores indicators of design fixation by following the development of the design ideas of a group of primary school children (age 10-12) carrying out a co-design project. Our goal is to find ways to improve the early mastering of DT (Diverging Thinking) and CT (Converging Thinking) skills, which in turn will help them to develop their creative abilities. The case study presented here indicates that the children showed adherence to the initial design idea and a lack of openness for divergent thinking at some points in the later stages of the design process, which led to little or no development of their design idea. Furthermore, we observed that the occurrence of design fixation in later stages of the design process has a negative influence on the creative development of the design idea. We grouped moments indicating design fixation into four categories that emerged from the data, which we named: "Band-aids", "Already taken care of", "Question not used for elaboration" and "It's not possible". We expect that these categories we found, which could be classified as indicators, will be helpful for a facilitator in identifying design fixation during the design process and adjusting the facilitation techniques accordingly. We expect these indicators to be present in sessions with students on different educational levels, which make these findings relevant to the education of future design professionals.


In order to study the influence of added polyester fibre on the intensity of cement-stabilized macadam,by experiment obtained were the variation laws of the compressive strength and splitting strength of cement-stabilized macadam with the fibre adding rates.This paper analyzed the mechanism of the influence of polyester fibre on the intensity of cement-stabilized macadam,and suggested the optimal adding rate of polyester fibre based on intensity indexes.The experimental results showed that the splitting strength was more sensitive to the polyester fibre adding rate than the compressive strength and the optimal content of polyester fibre would be around 0.70×10-3.


The present invention provides a non-aqueous electrolyte secondary battery including a positive electrode, a negative electrode and a non-aqueous electrolyte. The working upper limit potential of the positive electrode is 4.3 V or more with metal lithium as reference. In addition, the positive electrode includes a positive electrode active material layer including a positive electrode active material, an electrically-conductive material having a DBP oil absorption of above 150 ml/100 g, and an inorganic phosphoric acid compound having an ion conductivity.


Following a design phase of more than four years, construction has finally begun on the Smithsonian Institution's National Museum of the American Indian, which will occupy one of the last undeveloped sites on the National Mall, in Washington, D.C. The museum, scheduled to open by 2004, will be located next to the popular National Air and Space Museum with a direct view of the U.S. Capitol. The entire building may be said to resemble a series of weather-worn limestone cliffs. The structure is supported by friction-resistant, epoxy-coated steel driven piles. The complex geometry of the perimeter walls requires that most of the perimeter columns offset one another at each floor, necessitating cantilevers and transfer girders. Additionally each spandrel beam is curved in plan. Where architectural requirements limited the depth of transfer beams, full-height wall beams tie the floors together. A series of complex cantilevered stairways linking the floors encircle the space beneath the central dome. Most of the floor area reflects a beam-and-slab frame or flat-slab design. The museum is a reinforced-concret structure with the exception of two prominent features: the dome and a dramatic east roof cantilever system, which are of steel frame construction.


It is necessary and urgent to provide the analytical technical support to regulations aimed at curving fraud in food, pharmaceutical, and dietary supplements, to protect public health and allow fair trade.https://doi.org/10.21423/jrs-v05n01pi (DOI assigned 4/17/2019)


The Chinese Coastal Acoustic Tomography (CAT) system was developed for measurement of currents in the coastal sea. The CAT system was composed of two stations and each station was equipped with a GPS and a transducer. The operating frequency range of CAT system was 3–7.5 kHz. The reciprocal sound transmission experiment was carried out in March 25–26, 2009 in the Luotou Channel, near the Zhoushan Island, China. The sound signals using a carrier of 5 kHz modulated with M sequence of 9th order, were successful received at two stations. The mean signal to noise ratio reached about 19–21 dB. The range-averaged current velocity obtained along the transmission line measured by CAT was in good agreement with that measured by the lowed acoustic Doppler current profiler, producing the root-mean-square difference of 0.095 m/s. The above field experiment results indicated that the CAT system operated correctly.


Wireless sensors networks have severalapplications of their own. These applications can furtherenhanced by integrating a local wireless sensor network tointernet, which can be used in real time applications wherethe results of sensors are stored on the cloud. We proposean architecture that integrates a wireless sensor networkto the internet using cloud technology. The resultantsystem is proved to be reliable, available and extensible. Inthis paper a new framework is proposed for WSNintegration with Cloud computing model, existing WSNwill be connected to the proposed framework. Threedeployment layer are used to serve user request ( IaaS,PaaS, SaaS) either from the library which is made fromdata collected from data centric DC by WSN periodically.The integration controller unit of the proposed frameworkintegrates the sensor network and cloud computingtechnology which offers reliability, availability andextensibility. Keywords-Saas,Paas,Iaas,Dynamo DB


An up-link framing apparatus in a mobile communication system and an up-link framing method of the same are provided to minimize an up-link framing period in a system for supporting a shift frame block. A high MAC unit sets a connecting state with a base station. The high MAC unit receives, buffers, and stores a data packet from an upper layer. The high MAC unit generates SDU header information on the buffered data packet and generates MAC PDU. A low MAC unit receives and stored the SDU from the high MAC unit. The low MAC unit stores circular queue head and tail pointer information, analyzes an up-link map received from the base station, and reports an assigning state of a radio resource to the high MAC unit.


The incidence of anterior cruciate ligament (ACL) injuries is on the rise due to increased physical and sports activities. Thus, ACL reconstruction is a common surgical procedure to treat ACL ruptures, however, it has a failure rate of 0.7–21% and only 63% of the patients are able to recover to their pre-injury sport level. Orthobiologics, including platelet-rich plasma (PRP), growth factors, and stem cells, are being explored as alternative treatment methods to maximize the results and reduce surgical morbidity and healing time. PRP is derived from a blood sample with high platelet concentration and containing growth factors and interleukins. Studies have shown that PRP can improve the maturation of ACL reconstruction but more research is required to support its use in ACL surgery. On one hand, growth factors play a crucial role in ligament healing and PRP, which contains high levels of growth factors, has been shown to stimulate angiogenesis and encourage cell proliferation. On the other hand, stem cells have the ability to differentiate into other cell types and limit the inflammatory microenvironment during acute ligament injury. Ligament-derived stem cells show better potential for lineage-specific tendon/ligament differentiation when used with differentiation inducers. The use of stem cells in ACL reconstruction is still in the early stages of investigation. Therefore, cell therapy agents have shown promising results in preclinical models, but more research is required to determine the most effective biological agents for treatment.


The influence of one time administration of melipramine, amitriptilin, noveril and pirasidol per os. on cats was studied. EEGs of 8 cerebral structures were fixed and analyzed. Cluster analysis revealed that the power increased in δ− and θ%activity ranges and decreased within other frequency ranges.


Today, more and more training and education are taking place on the Internet or intranet. Consequently, traditional teaching and learning skills need to change in order to gain the maximum benefit from virtual learning. Discusses three different learning theories, namely behaviourism, cognitivism, and humanism. Traditional classroom teaching tends to use the behaviourist and cognitivist approaches, where the instructor tends to control the learning. However, a virtual learning classroom lends itself to a more humanist approach, where learners can take control of their own learning. In addition, the virtual classroom can encourage experiential and collaborative learning. Consequently, tutors need to be able to facilitate learning and group processes rather than instruct the learners or communicate information. Develops, compares and contrasts two models of learning, that of the traditional classroom and that of the virtual learning environment. Finally, in order to enhance virtual learning in groups, a num...


Critic of a "purely impure" philosophy of our age. Corporate diversityand one of its central figures and cornerstone texts : Sheryl Sandberg andLean In.


We report on high temperature stability of a near1.5 μm laser synthesized on an InP (001) substrate. Self-organized InAs quantum dots capped with a thin GaAs layer were used as an active region of the laser. An InGaAsP quaternary alloy having the bandgap energy of 1.15 eV was utilized as a waveguiding/matrix layer. A high characteristic temperature of the threshold current of T0 = 205K, evaluated in the temperature range of 20−50◦C, was achieved in ridge waveguide laser diodes. A correlation of T0 values with the bandgap energy of the waveguiding layer was found. Физика и техника полупроводников, 2017, том 51, вып. 10


In discussing the value of wood in relation to internal and external trade, my remarks will be confined to the trade in sawn timber, the value of this product on selected overseas markets, and the effect of world lumber prices on stumpage within New Zealand and their repercussions on the sawmilling industry. This paper has been prepared in my capacity as a member of the Institute and does not necessarily (or even perhaps remotely) reflect the official views of the N.Z. Forest Service. As an opening gambit, let me say that Russia has indirectly proved to be the best salesman for N.Z. Douglas fir on the Australian market, while the Japanese have indirectly been more effective in promoting "farm forestry" in New Zealand than anyone else. I say this to illustrate that New Zealand can no longer follow an insular approach in valuing sawn timber and the standing forests supplying the raw material. The value of wood is basically no different from the value of anything else, being precisely the amount that someone is prepared to pay for it at a given time. At present the Japanese are prepared to pay high prices for logs from New Zealand and elsewhere. The high price they are now paying for Russian logs has caused an increase in the value of North American logs and lumber of greater magnitude than would have normally occurred. This in turn has influenced prices of North American lumber in Australia and the higher prices now being charged have been the most effective fillip given to sales of N.Z. Douglas fir in that country — hence my first remark. The Japanese are now paying stumpages three times higher than can be paid by local sawmillers in parts of the North Island of New Zealand, with the result that farmers living within striking distance of a port are now boggling at the sort of money being offered for standing timber, which often was a liability until recently— hence my second remark. Before examining the effect of these world prices on the New Zealand scene, it is necessary to examine what has caused the changes and consider whether their effect is long-term or temporary. Therefore, the first study must concern the Japanese supply/ demand forecasts. In 1955, Japan imported a mere 88 million cu.ft of logs, but by 1967 this trade had grown to 928 million cu. ft, with significant quantities of sawn timber and chips also being imported. The Japanese Forest Agency predicts that Japan will require even greater volumes of imported logs and/or sawn timber till 1985, after which there will be a gradual drop to 833 million cu. ft in 1995 and 674 million cu. ft by the year 2000. These import demands could prove conservative, as they presuppose a more dramatic increase in domestic production than has been achieved in the past (see Fig. 1). From this it is clear that Japan offers a continuing market for logs and/or sawn timber through to the year 2000.


For a long time, the major problem area for researchers is disease diagnosis and the main interest of the medicine is an accurate diagnosis. Many engineering techniques have been developed in the past to help the medical staff with a diagnosis tool. There are many traditional methods of disease diagnosis, but the application of machine learning techniques has given a new dimension to this area. In this work, two different approaches have been used for the purpose of classification between diabetic and non-diabetic, using Pima Indian Diabetes Dataset. Principal Component Analysis has been used in the purpose of feature dimension reduction before applying any proposed classifier. Support Vector Machine (SVM) and Naïve Bayes (NB) are the two classifiers used in our study. 94.14 % and 93.88% are the accuracies obtained for the SVM and NB approaches.The results obtained are very interesting and show improvement from the previous works. With this accurate learning technique, there is enough scope for improvement considerably in this field.


This thesis investigates the structure of DPs in Jordanian Arabic (JA) focusing on Nominal Ellipsis (NE). Cross-linguistically, research on NE has produced a number of perspectives on the mechanisms involved in the licensing of NE. I argue that most of the mainstream approaches to NE cannot capture the full set of the ellipsis facts in JA, and that the ellipsis data in JA can be best captured under the ellipsis and stranding approach of Saab and Lipták (2016). I show that ellipsis takes place at two levels inside the DP, and that pronominalization arises as a by-product of a stranded affix scenario due to the application of ellipsis at the lower NP level. The investigation of NE in JA has implications for the structure of DPs containing numerals and for possessive DPs. It will be shown that that two classes of numerals in JA occupy different structural positions in the extended nominal projection giving rise to different agreement patterns and affecting the possibilities of ellipsis. As concerns possessive DPs, I investigate the behaviour of the Construct State and Free State constructions under ellipsis. I argue that the two constructions behave differently under ellipsis, and that the possessor DP merges in different positions. Overall, this thesis contributes significantly to the debate on the necessary conditions(s) for ellipsis licensing in the DP. It also has implications for the structure of the DP in Arabic.


The introduction of modern cross-sectional imaging modalities like computed tomography and magnetic resonance imaging has greatly facilitated the evaluation of normal anatomy and pathology of the deep spaces of the head and neck. These spaces are difficult to assess clinically 1• Not only the extent of tumors but also the spread of infections is well documented. This information leads to a better choice of therapeutic strategies. One of the major implications of imaging of the deep facial structures is to differentiate a parotid mass from a mass lesion outside the parotid gland. A parotid lesion necessitates a parotidectomy, whereas an extra-parotid tumor may be removed surgically without touching the parotid gland. Also the radiotherapist benefits from knowing exactly where the lesion is to deliver locally high doses and to spare the adjacent normal tissues (involved field technique).


In this paper, ripple energy of single-phase switched boost inverter (SBI) is analyzed, and the amount of low-frequency ripple present in the switch-impedance network parameters is estimated. It is found that larger passive components are required to maintain smaller ripples resulting in poor power density. So, integration of the single-phase SBI with an independent Boost-type active power decoupling (APD) topology is proposed to deflect the low-frequency ripple to an auxiliary capacitor. Thus, the low-frequency ripple on inductor current and capacitor voltage of the switch-impedance network is significantly reduced and much smaller passive elements are required only to filter high-frequency ripple. A passive element selection procedure for the switch-impedance network and APD topology is presented. To properly mitigate the low-frequency ripple of the SBI and also to avoid overcharging of the auxiliary capacitor, a closed loop control strategy is developed for the APD topology. The proportional-resonant (PR) current controller is chosen due to its low steady state error while tracking ac signals. A hardware prototype of the proposed system is fabricated and its performance is demonstrated.


This paper builds on the results of the ESANN 2019 conference paper "Privacy Preserving Synthetic Health Data" [16], which develops metrics for assessing privacy and utility of synthetic data and models. The metrics laid out in the initial paper show that utility can still be achieved in synthetic data while maintaining both privacy of the model and the data being generated. Specifically, we focused on the success of the Wasserstein GAN method, renamed HealthGAN, in comparison to other data generating methods. In this paper, we provide additional novel metrics to quantify the susceptibility of these generative models to membership inference attacks [14]. We also introduce Discriminator Testing, a new method of determining whether the different generators overfit on the training data, potentially resulting in privacy losses. These privacy issues are of high importance as we prepare a final workflow for generating synthetic data based on real data in a secure environment. The results of these tests complement the initial tests as they show that the Parzen windows method, while having a low privacy loss in adversarial accuracy metrics, fails to preserve privacy in the membership inference attack. Only HealthGAN shows both an optimal value for privacy loss and the membership inference attack. The discriminator testing adds to the confidence as HealthGAN retains resemblance to the training data, without reproducing the training data.


A method of separating a cyclic macrolide compound from a mixture comprising a cyclic macrolide compound and at least one of its analogues, wherein the mixture is subjected to column chromatography on silica gel using an identifier agent asymmetry immobilized gel silica, wherein the cyclic macrolide compound is tacrolimus and the identifier asymmetry agent immobilized on silica gel is a modified polysaccharide carbamate immobilized on silica gel or modified with an optically active amine immobilized on silica gel synthetic polymer.


The SwissFEL injector test facility at the Paul Scherrer Institute has been in operation since August 2010. Its primary goal is the demonstration of a high-brightness electron beam as it will be required to drive the SwissFEL main linac. The injector further serves as a platform for the development and validation of accelerator components needed for the SwissFEL project. We give an overview of recent commissioning activities at about 130 MeV beam energy, with particular emphasis on results from optics matching studies and emittance measurements, the latter obtained with different optics-based methods. A five-cell transverse-deflecting cavity allows studies of the longitu dinal bunch charge distribution and slice emittance. Bunch length measurements will become the focus of interest after the installation of a magnetic compression chicane, completed in the summer of 2011.


In this paper, the Extended Describing Function (EDF) is used to model a wireless power transfer (WPT) system with Series-Series (SS) compensation. Different control strategies used to control the output voltage are compared. The control parameters used to perform the control is the input voltage, the duty cycle and the operating frequency. The control to output voltage Laplace transfer functions are derived and the respective PID controllers are designed. The dynamic behaviors of the closed-loop systems are compared through Simulink simulations.


This dissertation initiates an ambitious project proposed by AIRBUS Defense & Space America to design a new
tethered space system for debris collection. The present study starts with the conception of a theoretical model
of the behavior of the system based on a Newtonian description. In order to verify the validity of the theoretical
model, a whole set of experiments have been designed to assess the system behavior. All this has been possible
thanks to theMIT Space Systems Laboratory SPHERES facility.
With the objective to conduct a further validation of the designed model aMatlab-SIMULINK model of the tether
has been created to do time dependent simulations. This system has been integrated with the existent SPHERES
Matlab-SIMULINK model available for laboratory scientists to simulate their own tests. With this simulation, the
theoreticalmodel can be directly validated.
Through the analysis of both experimental and simulations data, streams of improvement have been found. The
conception of a complete estimation system will be necessary to make further research of the control of the studied
tethered system.
Key areas of improvement have been stated. Major consequences of the system actions such as pulls, collisions
and winding of the tether have been highlighted to set the basis of this of what is meant to be a fully operative
system for spatial debris collection.


Preliminary to an investigation of the Szilard-Chalmers process in crystalline phosphates we wished to test the reliability of the separation of pyrophosphate from orthophosphate.


This paper has been written as part of the SUTRANET project (Work Package 1). SUTRANET (' Su stainable Tra nsport Research & Development Net work in the North Sea Region') is a project within the framework of the Interreg IIIB North Sea Programme. The paper has been elaborated by a team of researchers at Aalborg University, Department of Development and Planning. It has benefited from useful comments and contributions received from other partners of SUTRANET.


Internet of Medical Things (IoMT) is igniting many emerging smart health applications, by continuously streaming the big data for data-driven innovations. One critical obstacle in IoMT big data is the power hungriness of long-term data transmission. Targeting this challenge, we propose a novel framework called, IoMT big-data Bayesian-backward deep-encoder learning (IBBD), which mines deep autoencoder (AE) configurations for data sparsification and determines optimal tradeoffs between information loss and power overhead. More specifically, the IBBD framework leverages an additional external Bayesian-backward loop that recommends AE configurations, on top of a traditional deep learning loop that executes and evaluate the AE quality. The IBBD recommendation is based on confidence to further minimize the regularized metrics that quantify the quality of AE configurations, and it further leverages regularization techniques to allow adjusting error–power tradeoffs in the mining process. We have conducted thorough experiments on a cardiac data streaming application and demonstrated the superiority of IBBD over the common practices such as discrete wavelet transform, and we have further generalized IBBD through validating the optimal AE configurations determined on one user to other users. This study is expected to greatly advance IoMT big data streaming practices toward precision medicine.


To fashion a successful contractarian argument for the necessity of a certain kind of political institution is no mean feat, and Hobbes purports to have done so. But does his argument work? In my book' I tried to determine whether or not Hobbes can keep the assumptions of his argument and still draw the conclusions he wants. Some of the conclusions I managed to save, but his principle claim that a state must be headed up by a sovereign with absolute power I could not. In his paper, Professor Haji focuses on two of the theses that I claim to have saved: first, that people with the psychology Hobbes attributes to human beings would find the situation in which they were not politically governed a state of extensive conflict; and second, the claim that from this state of war it would be possible for people to generate, via some kind of agreement process, a political remedy. In my book, I point out that it is initially difficult to see how these two theses can fit together into the same argument: if the state of nature really is a state of war, how could its occupants cooperate to end it? And if its occupants are able to cooperate so as to end it, why shouldn't such cooperation be possible in the state of nature, making it a relatively peaceful state? Nonetheless putting these two ideas together is exactly what Hobbes or indeed any contractarian must be able to do if his or her contractarian argument is going to be internally coherent. Haji argues that one cannot keep both theses in a contractarian argument; in this comment I shall review his arguments, and maintain that he is wrong to think that they cannot coexist. Indeed, it is because they can coexist that the contractarian arguments remains a viable form of argument for political conclusions.


The son of a grocery owner details the operation of a family-run store in Koloa Japanese Camp. He also talks about barefoot football and baseball in the plantation camp. An auto parts salesman since 1932, he describes the auto business over the decades.


The influence of cytomegalovirus (CMV) infection as a co-factor in HIV-1 disease progression has mainly been studied in haemophiliacs and remains controversial. Based on the files of 1683 HIV-1-infected patients in the Seropositive Cohort (SEROCO) and Haemophiliacs Cohort (HEMOCO) cohorts, we studied the role of CMV infection in progression to CD4+ cell counts of less than 200 μl, AIDS onset and death, in various HIV exposure groups. Adjusted relative risk (aRR) of progression to AIDS and to death was respectively 1·30 (P = 0·05) and 1·58 (P = 0·007). In the sexual exposure group the influence of CMV infection on the risk of progression to AIDS was of borderline significance (aRR = 1·50; P = 0·07) and was more marked on the risk of death (aRR = 2·00; P = 0·03). No such influence of CMV infection was observed in the transfusion and intravenous drug use exposure groups. When we studied the influence of CMV infection according to the stage of HIV disease, the main effect was on progression from AIDS to death, probably because CMV disease is a late event. Sexual CMV transmission and frequent re-exposure to CMV may explain why CMV infection emerged as an important co-factor for HIV progression only in the sexual exposure group.


This work reports on the fabrication and characterization of recessed gate Pt-AlGaN/GaN HEMT H2 sensor. The device with partially etched AlGaN layer was obtained by cyclic plasma oxidation and selective chemical oxide etching. The recess depth of 12.3 nm and low RMS roughness were measured by AFM and the Pt/AlGaN interface was examined by STEM. The gate recess resulted in a ~1 V positive threshold voltage shift and in the reduction of the drain current due to lower 2DEG density in the gate region, as compared to non-recessed sensors. After the gate recess the sensing response increased from 0.4 % to 2.1 % and from 13.2 % to 42.2 % for 5 ppm and 300 ppm H2 concentration, respectively. A comparison of transient characteristics revealed a 1.7x faster response and 2x faster recovery time of the recessed-gate Pt-HEMT sensor at 250 ppm H2 concentration as well as low hysteresis.


As a multicomponent non-homogeneous plasticity building materials,it is inevitable that cracks exist in the interior of concrete.Damages to concrete from cracks are different due to different pouring places,different patterns of manifestation and different mechanisms of production.Starting with locations and manifestation patterns of several common cracks,this paper analyzes the formation mechanism of cracks and the damage to concrete structure from cracks,and puts forward methods to prevent the corresponding crack.


Objective To investigate the protective effects of the 14-3-3 protein overexpression on the injury of PC12 cell induced by MPP~+ and its mechanisms.Methods For expression in mammalial cells, pcDNA3.1(+)-14-3-3 plasmid was constructed and transfeeted into PC12 cell with Lipofectamine~(TM)2000. The overexpression of transfected 14-3-3 gene in PC12 cell was determined by immunofluorescence and Western blotting.The effects of 14-3-3 overexpressing on the cells viability,apoptotie ratio and the activity of superoxide dismutase(SOD)as well as glutathione peroxidase(GSH-Px)of PC 12 cell treated with MPP~+ were measured by MTT assay,flow cytometry analysis and microplate reader respectively.Results The expression of 14-3-3 protein in transfection group(1.19±0.06)increased evidently compared with control group(0.75±0.05).And the antioxidant enzyme activity assession,MTT assay and flow cytometry analysis shows that the overexpression of 14-3-3 protein elevates the activity of SOD(transfection group:(9.13± 0.41)U/mg protein,MPP~+ group:(6.45±0.52)U/mg protein)and GSH-Px(transfection group: (89.66±3.42)μmol/mg,protein MPP~+ group:(82.73±4.15)μmol/mg protein),increases the cell viability(transfection group:0.78±0.06,MPP~+ group:0.54±0.07),and inhibits cell apoptosis (transfeetion group:11.87%±3.26%,MPP~+ group:36.30%±2.39%)of PC12 induced by MPP~. Conclusion The overexpression of 14-3-3 protein could elevate the activity of antioxidant enzymes SOD and GSH-Px,reduce oxidant stress,alleviate MPP~+ toxicity,and thus inhibit the apoptosis of PC12 cell induced by MPP~+.


This paper deals with the development of a Decision Support System (DSS). The DSS (VESTA) aims to analyse the vulnerability of interdependent critical infrastructures in the context of natural disaster. The issues in this particular decision context are identified. Characteristics to be respected and the software architecture are presented. Various modules components of the system are described. The methodology presents different granularity of the implementation and the use of the DSS.


N AIR-FLUID level in the sphenoid sinus following acute head trauma can represent an early roentgenographic sign of significant basilar skull injury. Although post-traumatic effusion of tile sphenoid sinus has previously been described,"-" tile etiolog ' and significance of this finding has not been established. I)ong and his associates' reported 33 such patients witil appropriate skull roentgenograms obtained following head trauma. A large majority (90 per cent) had clinical signs of basilar skull injury. Ihev concluded that cerebrospinal fluid or sinusal hemorrhage at the floor of the anterior fossa cout(l drain by gravity into tue sphenoid sinus. Reynolds7 found frontal injury a prominent characteristic in his 14 patients but felt that nasal hemorrhage would not readily drain into an intact sinus. Duboula " has described the air-fluid level to be due to cerebrospinal fluid leakage. It is evident from the above that the significance of a sphenoid effusion found on skull roentgenograms following trauma is difficult to assess in the individual case. The question arises as to whether this finding represents (i) drainage of blood or cerebrospinal fluid from facial trauma through the sphenoid ostiuni into an intact sinus, or (2) extension of an undetected basilar or anterior fossa fracture into tile sphenoid body with mucosal laceration or cerebrospinal fluid leakage. The purpose of this paper is to attempt to determine more accurately tile significance, appearance, and composition of this roentgenographic finding. A clinical review of 50 patients with traumatic sphenoid effusion was made. MATERIAL AND ME'I'HODS


We report on the fabrication and the characterization of a design of highly birefringent solid-core photonic bandgap fibers. A form birefringence is obtained by keeping open all interstitial air holes but two diametrically opposite and close to the fiber core. Group birefringence as high as 0.57×10−3 and 0.47×10−3 at 1.1 and 1.55 μm, respectively, are demonstrated in the first bandgap.


The College of Medicine and Medical Sciences (CMMS), Arabian Gulf University (AGU) is adopting a problem-based curriculum promoting integration and student-centered approach to learning. This paper describes the CMMS experience in developing an undergraduate core curriculum which responds to the recommendations of international accrediting and regulatory bodies in medical education such as Accreditation Council for Graduate Medical Education, General Medical Council and others. The curriculum was structured around total of 110 presentations to reflect prevalent and important clinical (103) and community health problems ( ). The learning outcomes emanating from these presentations were integrated and linked with the following competency domains: medical (basic and clinical) knowledge, clinical skills, procedural skills, population health, communication skills and professional values. Basic and clinical sciences departments as well as students were all involved in planning and reviewing the core curriculum. This core curriculum will serve as a reference for planners of the different phases of the curriculum for selection and reviewing the current PBL problems in the curriculum, determining the gaps and linking assessment to the outcomes in high-stake examinations.


Hermeneutics of Medicine is the application of hermeneutics in the realm of medicine; it is a new realm of edge-cutting discipline between medicine and philosophy. This paper explores the history and main points of hermeneutics. Then we focus on the categories of medical hermeneutics, which includes phenomenology of body, the meaning of health and illness, doctor-patient relationship, medical ethics and the goal of medicine. Last section the effects of medical hermeneutics on philosophy of medicine and medical humanities are pointed out simply.


As the Earth's atmosphere warms, the atmospheric circulation changes. These changes vary by region and time of year, but there is evidence to suggest that anthropogenic warming causes a general weakening of summertime tropical circulation. Because tropical cyclones are carried along within the ambient environmental wind, there is an expectation that the translation speed of tropical cyclones has or will slow with warming.


This report dealt with co-operatives, primarily agricultural ones, in the Sisak-Moslavina County. The basic assumption is that founding different co-operatives, especially in the under-developed parts of Croatia, can affect the economic growth of the region. Consequently it could increase the living standard and influence positively on the demographic recovery of our country. While working on this report the methods of field interviewing and the Internet questionnaires were used. An employee of the Croatian Co-operative Alliance has been interviewed, while the questionnaires have been sent to 23 different addresses (both the Internet and the usual ones). There were 14 responses. Field work was done in the area of the town Petrinja and Velika Ludina region. The survey shows that the role of the existing co-operatives is not so essential for the development of the surveyed area. In spite of these facts they positively influence the economic and demographic development of the area where they are placed. To conclude, co-operatives could help in the economic turn off of the Sisak-Moslavina County, thus helping in the renewal and development of the area devastated in the recent war. But in the end their further development will depend on the local community attitude towards this issue.


[Objective] The study aimed to research the effect of litter layer,covering depth and their interaction on germination and early growing of Atremisia frigida.[Method] With the litter layer and A.frigida seeds as the tested materials,the 4 levels of covering depth(0,0.5,1.0 and 2.0 cm) and 4 weight levels of litter layer(0,50,100 and 200 g/m2)were set up to make the test according to randomized block design with two factors.[Result] The effect of covering depth on A.frigida emergence rate was remarkable.With the increase of covering depth,the A.frigida emergence rate was decreased.The emergence rate of covering depth of 1.0 cm was 5 times lower than that without covering.The emergence rate reduced to 0 when the covering depth raised to 2.0 cm.The litter had no significant influence on emergence,but it affected the growth including height and above-ground biomass noticeably.Small amount of weed litter layer(50-100 g/m2) was good for growth of A.frigida,while once the litter reached to 200 g/m2,the physical barrier effect would get obvious and the growth of A.frigida was greatly more worse than other treatments.[Conclusion] The litter layer and covering depth could all effect obviously A.frigida seedling establishment and the A.frigida emergence rate was effected by their interaction.


Service robots are developed with the assistance of rapidly growing aging and disabled population due to busy lifestyles of the human. Emotion recognition applications of service robots are still in developing stage. Service robot eye gets vision input to the intelligent system and finally give an output signal to the interaction part of the service robot. Therefore, robot eye design is an important factor to develop an accurate interacting service robot to care elders and disables. This paper introduces a method to develop an interactive service robot eye which has the capability to emotional recognition and expression based on the human motion by using haar cascade classification. Happy, sad and relax are the emotion types that elders and disables perform frequently. Therefore, intelligent system was developed to sense those emotions by training different classifiers for each emotion type. Parameters for haar classifier training involves the behavior of full body of the person by using the shapes of faces, hands, and legs. Developed robot eye was implemented and tested with different persons and finally, the results of the experiment are presented with the accuracy of the intelligent system to each tested person. According to the results, the emotions are detected more than 65% overall accuracy for each person.


In this work, we report on a program that aimed to expose high school students to nanotechnology. The program involved two NSF GK-12 engineering graduate fellows who developed a series of nanotechnology modules for an introductory engineering elective course in an urban public magnet high school. The fellows implemented the unit in two classrooms during the 2009–2010 school year. The unit was composed of multiple lessons that introduced students to some of the key concepts of nanotechnology, such as the relative magnitude of a nanometer, surface area to volume ratio, and nanoscale characterization. The effectiveness of the nanotechnology unit was measured by implementing a word association survey for each student. The responses from the students were categorized and tabulated by frequency. The results revealed that before the nanotechnology unit, students had perceptions about nanotechnology that were shaped by popular culture, movies, and video games. The survey given after the unit indicated a shift in the students' conceptions of nanotechnology. The unit presented here can be used as a model for inserting a nanotechnology focused unit into a high school classroom while still meeting core curriculum standards required by state governments.


By using the recent mathematical tools developed in quaternionic differential operator theory, we solve the Schrodinger equation in the presence of a quaternionic step potential. The analytic solution for the stationary states allows one to explicitly show the qualitative and quantitative differences between this quaternionic quantum dynamical system and its complex counterpart. A brief discussion on reflected and transmitted times, performed by using the stationary phase method, and its implication on the experimental evidence for deviations of standard quantum mechanics is also presented. The analytic solution given in this paper represents a fundamental mathematical tool to find an analytic approximation to the quaternionic barrier problem (up to now solved by numerical method).


While there are now many conferences on robotics, the International Symposium of Robotics Research (ISRR) is the most prestigious one in terms of quality and its historical background. The ISRR is sponsored by the International Foundation of Robotics Research (IFRR) and the goal is to bring together active leading robotics researchers from academia, government and industry to assess and share their views and ideas about the stateof-the-art of robotics. The 13th ISRR was held during November 26–29, 2007 in Hiroshima, Japan, with 24 invited papers and 17 selected from 46 submitted papers. To maintain the spirit of the ISRR since its inception, the International Symposium on Robotics Research, 2007 (ISRR07) kept the single-session format with a limited number of participants. In addition to officer's and video sessions, 11 technical sessions were organized: anthropomorphism, learning, understanding, mechanism, vision, sensing, planning, programming, manipulation, interaction and diamond. As a new "flavor" for the ISRR07, we especially organized the "DIAMOND" session of four papers that were selected as "clear and sharp shining" stones as an indication of the future robotics. All sessions were structured somewhat differently from regular conference sessions. Firstly, chairs had the opportunity to introduce the sessions and raise questions of relevant research areas. Secondly, more time was given to discussion, though it was never enough. After the symposium, 10 papers were selected for this special issue of The International Journal of Robotics Research (IJRR). After review by two specialists for each paper, we eventually decided to publish six excellent papers in this issue. Vasquez, Fraichard and Laugier propose an approach for incrementally learning a set of vehicle or pedestrian trajectories using growing hidden Markov models (GHMMs). The proposed system incrementally learns a topological map via the instantaneous topological map (ITM) Jockusch and Ritter algorithm. Editorial


The problem of stabilizing Networked Control Systems (NCSs) with random but bounded delays is discussed in this paper. By using an augmented state‐space method, this class of problem can be modeled as a discrete‐time jump linear system governed by finite‐state Markov chains. As the network‐induced time vary delay of NCSs changes along with the network transferring route and the network load, results in systems becoming instable with controller designs based on a fixed transition matrix, we firstly make use of the V‐K iteration algorithm to design m groups of stabilizing controllers that satisfy different m transition matrixes, and then constitute a switched controller for them and a switch. The simulation shows that if the switched controller is used to stabilize the discrete‐time jump linear system, this system not only has a larger stabilizing span, but also has better dynamic stabilizing characters compared to those with only one group of controllers.


The SAGE project will recruit, train, and financially support Native and non-Native students as they complete their concentration practica. SAGE students are awarded paid practicums and will complete 360 hours of their field education either in American Indian Country or with American Indian populations, providing students with the necessary experience to transition into employment in Indian Country.


For a learner it is difficult to find a path of learner activities yielding a certain learning goal. The desired path depends on various variable, be it the amount of time available, the knowledge the learner already has, the difficulty of the learning objects and so on. The TENCompetence Curriculum Planner Service provide means to compute a sequence of learning objects tailored to the learners eeds. Its reasoning bases on a set of learning activities metadata specifying the pre and post conditions of each learning activity, the number of credit points a learning activity has, and the learner profile, i.e., the knowledge of the learner and the courses she already attended. This document describes the functionality of the Curriculum Planner Service and the way it has to be called.


According to the nature of the journal and classification of subjects,Journal of China Capsicum was classified by its quantity of literatures.Results suggested that in 2009,67.74% of papers in Journal of China Capsicum were related to academic research,and the literatures about horticulture accounted for 47.57% of the general amount.There were few papers on other subjects.Hence,Journal of China Capsicum belonged to scholarly journal about horticulture.


Background:
 Chronic diseases are prevalent in Canada's aging population (≥65 years). Positive health behaviours (e.g., physical activity, healthy diet) are critical for the management of chronic diseases (e.g., stroke, heart disease). However, novel coronavirus (COVID-19) prevention strategies of quarantining, social isolation, and physical distancing may compromise one's ability to manage health and engage in daily activities, possibly increasing risk of adverse health events. The Community Outreach teleheAlth program for Covid education and Health promotion (COACH) program has demonstrated an increase in health promoting behaviours, but little is known about participants' experiences in participating in the program. The program entailed six telehealth sessions over two months that focused on health coaching, behaviour change, and COVID education. The objectives of this study were to describe: (1) chronic disease prevention and management strategies of older adults (≥65 years of age) during COVID-19; and (2) participants' experience in COACH sessions delivered by medical students at the University of British Columbia.

 Methods:
 Twenty-four COACH participants participated in semi-structured interviews that were conducted through Zoom videoconferencing. Interview questions focused on how participants managed their own health before and during COVID-19. Qualitative description was the guiding methodological framework. Interviews were transcribed verbatim and analyzed thematically.

 Findings:
 Participants' mean age was 73.4 years (58% female) with 75% reporting two or more chronic conditions (e.g., stroke, heart disease, coronary artery disease, diabetes, heart attack). Three themes described participants' prevention and management strategies, including: i) having a purpose for optimizing health; ii) using internal self-control strategies; and iii) leveraging external support strategies. COACH further supported participants during COVID-19, as represented through coach interactions as well as knowledge and skill development.

 Conclusion:
 Findings suggest that older adults engage in internal self-control strategies and external support means to manage current chronic conditions and promote health and well-being. Health professional program students have a potential role in health promotion and in assuming the role of coach in telehealth promotion programs for older adults.


S OF CARDIOLOGY Thrombosis and Embolism of Pulmonary Vessels with Special Reference to Pulmonary Vein Thrombosis. D. M. SPAIN and J. B. MOSES. Amer. J. med. Sci., 212, 707-712, Dec., 1946. The general incidence of pulmonary emboli or thrombi in a series of 1000 consecutive necropsies (not inclusive of bacterial endocarditis and traumatic cases) was 10-9%. The source of emboli in the lungs is approximately twice as frequent from the systemic veins as from thrombi within the heart. Pulmonary emboli in patients without heart disease frequently do not cause pulmonary infarcts. In 100 consecutive necropsied cases of myocardial infarction, pulmonary emboli were noted 36 times and systemic arterial emboli 25 times. The incidence of pulmonary emboli is much greater in association with recent myocardial infarcts than with healed infarcts. The pulmonary emboli very often contributed to the death-of the patient. Pulmonary venous thrombi as a source of systemic arterial emboli occur more frequently than is generally recognized. Pulmonary tuberculosis was the disease most often associated with pulmonary venous thrombi. Infected emboli resulting from pulmonary thrombophlebitis are exceedingly rare.


Large scale Bayesian model averaging and variable selection exercises present, despite the great increase in desktop computing power, considerable computational challenges. Due to the large scale it is impossible to evaluate all possible models and estimates of posterior probabilities are instead obtained from stochastic (MCMC) schemes designed to converge on the posterior distribution over the model space. While this frees us from the requirement of evaluating all possible models the computational effort is still substantial and efficient implementation is vital. Efficient implementation is concerned with two issues: the efficiency of the MCMC algorithm itself and efficient computation of the quantities needed to obtain a draw from the MCMC algorithm. We evaluate several different MCMC algorithms and find that relatively simple algorithms with local moves perform competitively except possibly when the data is highly collinear. For the second aspect, efficient computation within the sampler, we focus on the important case of linear models where the computations essentially reduce to least squares calculations. Least squares solvers that update a previous model estimate are appealing when the MCMC algorithm makes local moves and we find that the Cholesky update is both fast and accurate.


Schizophrenia is one of the most devastating psychiatric disorders. Most second-generation antipsychotics (AP [SGAs]) that are commonly prescribed for its treatment can induce substan-tial weight gain in susceptible individuals. It was estimated that over the course of treat-ment with the majority of SGAs, up to 50% of patients develop metabolic abnormalities with increased risk of cardiovascular disor-ders (CVD) and mortality


Taking a typical model for example, the mould design and fabrication process for vacuum assisted RTM with a flexible mould are introduced .It proves suitable for manufasturing complicated composite components.


It began with an understanding that sustained and appreciable improvements in early childhood development were not going to take place without meaningful public engagement and a more unified, collective approach to addressing the critical years in child development-conception to three years. This challenge underpinned the communications research partnership between the Centre for Community Child Health (CCCH) and the FrameWorks Institute of Washington, DC.


Before considering dysfunctional bleeding it would seem appropriate to examine functional uterine bleeding or the normal menstrual cycle. Functional uterine bleeding is the end result of an elegant and intricate series of physiologic events whereby an endometrium is caused to grow and mature under the influence of estradiol and to regress and be shed following ovulation and production of progesterone. The event of menstruation occurring as a result of decreased levels of both estrogen and progesterone is the hallmark of a competent menstrual cycle and for the most part occurs in an efficient and predictable fashion acceptable to patient and physician alike. Recent advances in our understanding of the normal menstrual cycle or functional bleeding have aided in our diagnosis, understanding, and management of dysfunctional uterine bleeding, its counterpart. While many gynecologists stress that all dysfunctional uterine bleeding is anovulatory and others that it may be anovulatory and dysovulatory as well, most agree that it is abnormal bleeding that occurs without evident organic pathologic factors. Since dysfunctional uterine bleeding occurs when one or more of the physiologic processes responsible for cyclicity is disrupted to the extent that normal function is impaired. It is evidenced by a change in the bleeding pattern and/or altered fertility. Bleeding resulting from a disturbed menstrual cycle is one of the most common disorders confronting a gynecologist. Its recognition as bleeding that occurs from estrogen withdrawal or breakthrough or in instances in which ovulation has occurred but progesterone production is either indequate or persistent is essential for effective management of the problem. In patients whose bleeding results from a menstrual cycle disturbance, histologic examination of the endometrium may reveal a proliferative pattern, a mixed pattern, or a hyperplastic progression resulting from excessive and unopposed estrogen stimulation. The true incidence of uterine bleeding as a result of a menstrual cycle disturbance is difficult to estimate. It is encountered commonly in a physician's office but less so among gynecologic patients hospitalized for medica or surgical management. It would seem reasonable to suspect that of all patients who present with dysfunctional bleeding, about one-fourth will be adolescents and one-half perimenopausal. This is not surprising, as cycle disturbances are seen more commonly in the adolescent when full maturation of the hypothalamicpituitary-ovarian axis has not yet occurred and in the latter years of menstruation when lack of ovarian responsiveness can explain the abnormal bleeding patterns. While dysfunctional uterine bleeding is seen more often in the beginning and near the end of a woman's menstrual years, alterations in a previously established pattern may occur at any age.


Dielectric layers are formed on a substrate by a subatmospheric chemical vapor deposition (SACVD) of ozone-tetra-ethyl-ortho-silicate (O The treatment with UV-radiation may increase In addition, the UV treatment can also be the amount of silanol in the O


The course of engineering drafting uses multi media CAI teaching and network teaching, stress the teaching of projection drafting, with CAD in engineering drafting, and introduce new design concept in the course to improve students' engineering sense.


Broad Gaussian luminescence bands with large Stokes shift from free exciton absorption bands have been observed at 11.7 kcm -1 and 11.1 kcm -1 in mercurous halide single crystals of Hg 2 I 2 and Hg 2 Br 2 , respectively at 4.2 K. The excitation spectra and the temperature dependences of the peak energy, the intensity and the decay time have been studied in the above two luminescence bands. A model of self-trapped triplet excitons having two excited states separated by 70 cm -1 is proposed in order to explain the experimental results of the luminescence. The importance of interactions of a mercury diatomic molecule with ten neighboring halogen atoms is suggested from the unpolarized nature of the luminescence.


WITH THE PURPOSE OF RECOGNIZING THE LOCALITIES AND THE REGULARITY OF OCCURRENCE OF THE RED TIDES, THE SPECIES WHICH CAUSE IT AND THE TOXICITY OR NOT OF ITS CELLULAR PRODUCTS, PLANKTOLOGICAL STUDIES MADE DURING 1980-1992 ON THE PACIFIC COAST, IN THE GULF OF MEXICO AND IN THE CARIBBEAN, USING QUALITATIVE AND TEST (UTERMHL TECHNIQUES BY INVERTSCOPE FOR MICROPLANKTON OF WADER SAMPLES) WERE INTEGRATED. FORTY RED TIDE WERE RECORDED, OF WHICH 30 OCCURRED IN THE LAST FIVE YEARS (1987-1992). THIRTEEN WERE TOXIC, PRODUCED BY: PYRODINIUM BAHAMENSE (2), GYNODINIUM CATENATUM(3), PROTOPERIDINIUM TROCHOIDEUM (2), PROTOPERIDINIUM SP.(1), GONYAULAX TRIACANTHA (1), GYMNODINNIUM SPLENDENS (1), ALEXANDRIUM SP. AND GONYAULAX SPP. (1) GYMNODINIUM BREVE (1), AND PROROCENTRUM MINIMUN (1), NOCTILUCA SCINTILLANS (3), CERATIUM FURCA (4). THEIR MAGNITUD VERIED FROM 100 HA (TOXIC) TO 8000 KM2 (TOXIC), WHIT DENSITIES OF 17 000 000 AND 1 090 000 CELLS/1, RESPECTIVELY.


The utility model discloses an intelligent operating room is with energy-saving air treatment system, include through the consecutive following part of tuber pipe, air-handling unit (1) for carry out filtration treatment to outdoor new trend (2) and indoor new trend (3), electrical heating unit (5), for tuber pipe type electric heater, electrical heating unit (5) are located certainly on the delivery line of air-handling unit (1) air-out for carry out the electrical heating operation to output wind, and noise elimination static pressure case group is for first noise elimination static pressure case (6) and the second noise elimination static pressure case (7) that adopts a plurality of circulating fan (4) parallelly connected pipeline to connect, wherein, new trend and warp after the electricity adds thermal treatment the return air that noise elimination static pressure case group carries out the deadening passes through the mixed back of three-way valve, after heating, sterilization, locates certainly the air supply static pressure case (9) at intelligent operating room top is inputed to the operating room in. The disclosed intelligent operating room is with energy-saving air treatment system of present case is energy-conserving to be reached more than 50%.


We show that if the sum of the resistances of an electrical network N is finite, then there is a unique electrical current in N, provided that we do not allow, in a sense made precise in the paper, any flow to escape to infinity.


FIELD: chemistry. SUBSTANCE: invention relates to novel antagonists of serotonin 5-HT 6 receptors - substituted 2-amino-3-sulfonyl-6,7,8,9-tetrahydro-pyrazolo[1,5-a]pyrido[3,4-e]pyrimidines of general formula 1 and substituted 2-amino-3-sulfonyl-5,6,7,8-tetrahydro-pyrazolo[1,5-a]pyrido[4,3-d]pyrimidines of general formula 2 or their pharmaceutically acceptable salts and/or hydrates, method of producing said compounds and pharmaceutical compositions, medicinal agents and treatment method. In compounds of formula 1 and general formula 2 , Ar is phenyl which is possibly substituted with halogen atoms, or a 6-member nitrogen-containing heteroaryl; R 1 is a hydrogen atom, C 1 -C 3 alkyl which is possibly substituted with phenyl, C 1 -C 5 alkoxycarbonyl; R 2 is a hydrogen atom, halogen or C 1 -C 3 alkyl; R 1 3 and R 2 3 are optionally identical substitutes selected from a hydrogen atom, optionally substituted C 1 -C 3 alkyl or R 1 3 and R 2 3 together with the nitrogen atom with which they are bonded form a nitrogen-containing 6-member saturated heteroaryl optionally substituted with C 1 -C 5 alkoxycarbonyl, where the said heteroaryl has 1-2 heteroatoms selected from nitrogen. EFFECT: compounds can be used to prevent and treat diseases of the central nervous system, pathogenesis of which is associated with 5-HT 6 receptors for enhancing mental capacity. 14 cl, 3 tbl, 19 dwg, 16 ex


Disclosed is a phase plane self-adaptation control method based on a characteristic model. The method comprises the following steps: (1) a speed limit value in a jet control law is designed; (2) an angular speed maximum value of a stepped zone, an angular speed maximum value of a low thrust zone, a dead zone theta D and a stepped threshold value theta v in the jet control law are designed; (3) a high thrust zone threshold value theta B in the jet control law is designed; (4) a low thrust angular speed accelerated speed parameter ac2 and a high thrust angular speed accelerated speed parameter ac1 in the jet control law are calculated according to a golden ratio coefficient; (5) a stepped zone parameter kj in the jet control law is calculated according to the low thrust angular speed accelerated speed parameter ac2, and a parabola coefficient KX in the jet control law is calculated according to the high thrust angular speed accelerated speed parameter ac1 and other phase plane parameters; (6) the controlled quantity is calculated according to parameters designed in the above-mentioned steps and a phase plane jet control logic, namely, the jet length of an engine is confirmed, and the engine is controlled within a sampling control period according to the confirmed control quantity.


The culture condition of Bacillus JY-LZ, one strain of probiotics that can produce lactic acid, was studied in shake flask. The optimum culture conditions were found. When volume of inoculum was 5~10%, temperature was 30~40℃, volume of media in 100ml flask was 30mL(K_La=177.5h~(-1)),and pH(before sterilization) was 7~9 , the 48h cell density was over 10~(10)/mL, and the sporulation rate was over 50%. The results show that the optimum culture conditions can be applied in practical production.


Objectives: Our primary objective was to determine the response rate; secondary objectives were to assess the toxicity rate, and disease-free and overall survival rates in patients with locally advanced breast cancer (LABC) receiving a cyclophosphamide (500 mg/m²), mitoxantrone (12 mg/m²) and 5-fluorouracil (500 mg/m²) (CMF) chemotherapy regimen. Patients and Methods: The data from 74 patients with LABC with neoadjuvant CMF chemotherapy were analyzed retrospectively. Preoperatively, all patients received 3 cycles of CMF on day 1, repeated every 21 days. In 3 (4.1%) patients, breast-conserving surgery was given and in 71 (95.9%) modified radical mastectomy. All patients received radiotherapy and 3 additional cycles of CMF chemotherapy after surgery. Results: Median age of the patients was 47 years (range: 17–74). 43 patients were premenopausal, whereas 31 were postmenopausal. 54 patients were in stage IIIA, and 20 were in stage IIIB. The overall clinical response rate was 88%; 11 (14.9%) had a complete response, 54 (73%) had a partial response, and 2 (2.8%) had progression. 14 (18.9%) had a pathological complete response. The median follow-up was 62 months. The median disease-free survival was 64.9 months, and the median overall survival was 97.5 months. The 5-year disease-free and overall survival rates were 52% and 79.9%, respectively. Most frequent side-effects were nausea/vomiting, mucositis, alopecia and leukopenia. Conclusion: The CMF regimen has a high overall response rate and an acceptable sideeffect profile in the treatment of locally advanced breast cancer. Further studies are needed to evaluate its effectiveness in breast-conserving strategies.


We study the spontaneous emission rate of emitter in a periodically patterned metal or dielectric membrane in the picture of a multimode field of damped Bloch states. For Bloch states in dielectric structures, the approach fully describes the Purcell effect in photonic crystal or spatially coupled cavities with losses. For a metal membrane, the Purcell factor depends on resistive loss at the resonant frequency of surface plasmon polariton (SPP). Analysis of an InP-Au-InP structure indicates that the SPP's Purcell effect can exceed a value of 50 in the ultraviolet. For a plasmonic crystal, we find a position-dependent Purcell enhancement with a mean value similar to the unpatterned membrane. Design of plasmon cavities for solid-state cavity quantum electrodynamics applications, " Appl. Spontaneous emission extraction and Purcell enhancement from thin-film 2-D photonic crystals, " J. Surface-plasmon-enhanced light emitters based on InGaN quantum wells, " Nat. Enhancement of spontaneous recombination rate in a quantum well by resonant surface plasmon coupling, " Phys. Lifetime of an emitting molecule near partially reflecting surface, " J. Modified spontaneous emission from a two-dimensional photonic bandgap crystal slab, " J. Design of mid-IR and THz quantum cascade laser cavities with complete TM photonic bandgap, " Opt. The photonic band edge laser: A new approach to gain enhancement, " J. Quantization and phase-space methods for slowly varying optical fields in a dispersive nonlinear medium, " Phys. Rev. Theoretical analysis on light-extraction efficiency of organic light-emitting diodes using FDTD and mode-expansion methods, " Org. Quantum analysis and the classical analysis of spontaneous emission in a microcavity, " Phys. Rev. Propagation and second-harmonic generation of electromagnetic waves in a coupled-resonator optical waveguide, " J. Active coupled-resonator optical waveguides. I. Gain enhancement and noise, " J. Full photonic band gap for surface modes in the visible, " Phys. Surface plasmon propagation in a pair of metal nanowires coupled to a nanosized optical emitter, " Opt.


Psychiatrists and psychologists are under increasing pressure to obtain board certification in their areas of specialization. While this has been the norm for psychiatrists, it is less true for psychologists as of this writing. Regardless, both professionals have been permitted to testify in court without board certification, particularly since the Federal Rules of Evidence 702 tend to be somewhat broad-based in their definition of what constitutes an expert. This article reviews the basic need for board certification and reasons why it should become a requirement for those who practice forensic psychiatry and psychology. The article considers some of the reasons why individuals in both professions may have been reluctant to pursue board certification in the past, as well as some of the pitfalls encountered in the process of becoming certified. Further discussion illuminates the need for psychiatrists and psychologists to adhere to rigid requirements for credentialing and to avoid dubious alternatives such as so-called "vanity" boards that offer ongoing grandfathering periods without rigorous credentials reviews and examination. The impact of such questionable credentials on the forensic field is also discussed.


We currently develop a technology to combine knowledge acquisition from domain experts and data mining thus allowing an easy and focused approach to intelligent knowledge discovery. By enabling the domain expert to enter data mining queries in his/her domain terminology and by returning findings in the same terms as well as measuring the interestingness of findings, user support is provided throughout the knowledge discovery process. In the biomedical area a project on the discovery of interesting dependencies in patient data for the purpose of quality management has been carried out within several clinics. In this sector, data mining precedes confirmative analyses by generating first hypotheses. In addition to that, a number of studies concerning the analysis of medical data, e.g. in the fields of in vitro fertilization, classification of tumors, fusion of sensor data, and diabetic patient profiling have been worked on with local university hospitals. By fusing complex medical data from various Sources and analyzing them, new discoveries, e.g. decision trees for tumors, could be made.


The Landmark Resort indoor pool complex is now reopen with a fresh, new look and features a lazy river, large pool and more!


Latvia's far right has had a great deal of political influence since the late 1980s, when nativist movements played a key role in mobilizing political opposition to Soviet power. Far-right parties have been in 16 of the 22 government coalitions in Latvia between 1993 and 2023. Since 2010, the National Alliance (NA), a merger between an established far-right party and a more youthful political party, has come to dominate Latvia's far right and has been a part of every government coalition from 2011-2023. This article begins with a discussion of Europeanization, the Europeanization of political parties, and the qualitative methodology used in the article to examine the impact of Latvia's membership in the European Union on NA's international links and program. The article then outlines the development and influence of Latvia's far-right. The following sections examine links between Latvia's far right and Europe's far right and the impact of Europe on NA's ideology and program. It finds little evidence of Europeanization of Latvia's far right. Latvia's far right is more hawkish toward Russia than the West European right and also enjoys greater domestic influence and respectability. "New nativist" anti-immigration and cultural Marxism themes have lower salience in Latvia where Russian-speakers are perceived as a bigger and more immediate threat than Muslims or "Woke" activists.


The organic contamination damage of large-aperture optical components limits laser energy improvement of inertial confinement fusion (ICF). In situ cleaning of large-aperture optical components via low-pressure plasma is expected to remove organic contaminants from the optical surface. Herein, low-pressure air plasma equipment was proposed and used on surfaces of SiO2 sol–gel antireflection (AR) films in situ by conducting experiments. Its electrical discharge parameters were investigated and optimized during plasma cleaning. Plasma diffusion characteristics and homogeneity in large-aperture windows were analyzed by optical emission spectroscopy. Dramatic degradation in the optical properties of components was observed after organic contamination for 5 h. Transmittance, laser-induced damage threshold and surface morphology observation results demonstrated that low-pressure air plasma removed the organic contaminants from the surface of sol–gel AR films without causing damage and metal contamination. After plasma cleaning, the hydrophilicity of the films increased significantly due to the increase in the polar components of surface free energy. The mechanism of plasma cleaning organic contaminants was confirmed by x-ray photoelectron spectroscopy measurements. These salient results provide a new alternative method for removing organic contaminants in situ from large-aperture optical components and a foundation for improving the energy output of the ICF system.


Probiotics have been reported to be efficacious against cancers, infections, allergies, inflammatory bowel diseases and autoimmune diseases, and it is important to explain how such multifunctional activities are realized. Lactobacillus casei Shirota (LcS) is one of these multifunctional probiotics, and its ability to augment the host immune system has been extensively examined. We have shown that the cell wall structure of this probiotic strain is responsible for potently inducing IL-12 production. In addition, we have recently found that LcS differentially controls the inflammatory cytokine responses of macrophages and T cells in either Peyer's patches or the spleen. Other studies revealed that LcS-induced IL-12 production by macrophages is modified when other bacteria or their cell components are simultaneously present. These findings can provide a theoretical basis for understanding the multifunctional activities of specific probiotics.


The invention discloses an in-situ preparation method of a silver functional coating. The in-situ preparation method of the silver functional coating comprises the following steps: carrying out ultrasonic dispersion modification on the surface of solid nano Ag, so as to obtain nano Ag paste; coating the nano Ag paste on the surface of a part base, and drying to obtain a nano Ag particle coating; placing a dried part with the nano Ag particle coating in protective atmosphere, insulating at the temperature of 200-450 DEG C, then carrying out furnace cooling, and completing catalytic decomposition of a modifier and in-situ crystallization of nano Ag particle, thus a Ag coating is obtained. The in-situ preparation method of the silver functional coating can effectively solve the problem that a cyanogen-containing plating solution produced in silver electroplating pollutes the environment; the Ag coating has metallurgy binding characteristic with a base interface, so that interface binding strength is improved; the in-situ preparation method is strong in technological adaptability, simple in technology and applicable to being widely popularized.


This paper presents a strategy addressing the problem of selection of the class of the amplifiers to be used in future wireless communication systems. The proposed methodology uses a scheme based on neural networks (NN): the characteristics of each class of amplifier (i.e., A, B, AB, C, D, F, G, J, S, $T$, etc.) are determined and then the 'classification NN' is constructed for distinguishing various classes from each other. To validate the method, firstly the designs of various class-amplifiers are collected from the recently published literature, and then the specifications of the amplifiers are extracted in terms of voltage (V), current (I) and efficiency; finally with these data the classification NN is trained. After building this black-box NN, providing the required specifications of each amplifier, designer are informed about the class of amplifier that is predicated by the classification NN and that better fits the characteristics of the considered application. This methodology is important as it leads the way of amplifier class selection in the complex communication systems.


This research goal to determine the relationship between social support husband with the confidence of mothers in exclusive breastfeeding. Samples from this research are 88 women who came to the Posyandu in the area Puskesmas Colomadu 1. The sampling technique of this research using accidental sampling technique. The method used in this research is quantitative method using a measuring instrument the scale of social support husband and the scale of confidence in exclusive breastfeeding mothers. The data analysis technique used is the correlation of Pearson Product Moment. Based on the analysis of data obtained by the value of the correlation coefficient (r) of 0,556 with sig. = 0,000; p <0,01 ; which means there is a significant positive relationship between social support husband with the confidence of mothers in exclusive breastfeeding. The effective contribution of social support husband to the mother's confidence in exclusive breastfeeding is equal to 30,91%, 69,09% so there are still other factors that affect the mother's confidence in exclusive breastfeeding. Keywords: social support husband, self-confidence, exclusive breastfeeding.


Objective:To study the expression and significance of connective tissue growth factor(CTGF) and transforming growth factor-bata1(TGF-β1) in murine liver fibrosis induced by Taenia saginata Asiatic from Duyun area.Methods: Establish the murine liver fibrosis model induced by Taenia saginata Asiatic from Duyun area,and subsequently killed at the 30th、40th、50th、 and 60th days respectively.The hepatic expression of CTGF and TGF-β1 was detected by immunohistochemical method.Histolog-ical changes of murine liver were observed by HE staining.Results: The murine liver fibrosis model induced by Taenia saginata Asiatic from Duyun area were successfully established at the 30th day.The hepatic expression of CTGF and TGF-β1 in the murine liver fibrosis models peaked at the 40th day and then declined.There existed positive correlation between the hepatic expression of CTGF and TGF-β1.Conclusion: The expression of CTGF and TGF-β1 is closely correlated to the development of the murine liver fibrosis induced by Taenia saginata Asiatic from Duyun area,and TGF-β1 may play its fibering roles by its action on CTGF.To block the CTGF signal transduction pathway may be a potential treatment of Taenia Saginata Asiatic liver fibrosis.


We observed an X-ray afterglow of GRB 060904A with the Swift and Suzaku satellites. We found a rapid spectral softening in the prompt tail observed by Swift. Adopting the absorbed power-law model to the observed spectra, the photon indices rapidly change from Γ = 1.2 ± 0. 1t o Γ = 5.3 +0.7 −0.6 . It is quite difficult to explain this ultra soft spectrum by the simple electron acceleration and the synchrotron radiation.