We present experimental and theoretical analysis of quantum fluctuation in a vacuum field in the presence of an orthogonal linearly polarized pump field propagating through a Rb vapor cell. Previously reported theoretical and experimental studies provided somewhat contradictory conclusions regarding the possibility of observing the 'squeezed vacuum'–the reduction of vacuum fluctuations below the standard quantum limit–in this system. Here, using the D1 transitions of Rb in a cell without a buffer as an example, we demonstrate that vacuum squeezing is corrupted by incoherent processes (such as spontaneous emission, elastic scattering, etc), and its observation is only possible in a specific small region of the experimental parameter space. Numerical simulations, in good agreement with the experiment, demonstrate that the two excited state hyperfine levels play a crucial role in the squeezing and excess noise production. The significant influence of far-detuned atoms on the field fluctuations at low noise frequencies imposes the explicit consideration of the full velocity distribution of the atomic vapor.


This paper has a brief introduction to a algorithm that can automatically identify the defective cutting region when automatic paper cutter does quality analysis. The algorithm analyzed the characteristics of processed shear mark image,detected defects,found a critical point of defective part ,then a unique regional recognition algorithm was developed based on the basis of the general processing algorithm. The algorithms can pinpoint the region that cutting defects exist according to the coordinates of critical point accurately, improve the efficiency of quality analysis, and also has stated that image processing is available in the regional recognition of automatic paper cutter.


We used the leaf blade of rice (cultivars were Nonghu 6, Sugeng 2, Huyou 2 and Hanfeng) as initial material for protoplast culture, and a great number of regenerated plants were obtained.


Abstract This paper explores representations of old age in the poetry of Ibn Ḥamdīs (444–527/1056–1133 CE). It shows how the poet, while adhering to a codified aesthetics, creatively reworked specific sub-genres of the "qaṣīda" into a personal 'poetics of ageing'. It is my contention that Ibn Ḥamdīs built such a poetics on binary constructions which parallel bodily deterioration with the collapse of social cohesion and the political decline of Islam in the West. The first part of the paper focuses on form. I discuss Ibn Ḥamdīs' usage of the theme of "aš-šayb wa 'š-šabāb" within a multipartite ode, showing how, according to an established tradition, the poet used canonical motifs of old age poetry as transitional segments, enhancing the poem's conceptual unity. The second part of the paper focuses on selected verses of nostalgia for the homeland ("al-ḥanīn ilà 'l-awṭān"), elegies ("riṯāʽ") and ascetic poems ("zuhd"). These sub-genres are read in conjunction in order to formulate a preliminary definition of Ibn Ḥamdīs' own 'poetics of ageing'.


Modern astronomy, quite rightly, dates its beginning from the work of COPERNICUS. Hence, historians of astronomy, dealing with the period between the publication of the De Revolutionibus in 1543 and the end of the sixteenth century, have centered their discussions upon the gradual acceptance of COPERNICUS' ideas, and their further development by the astronomers and scientists who followed him. Almost all such discussions, however, have overlooked the very important fact that in England, perhaps more than in any other country, an intelligent knowledge of the Copernican theory was spread among all classes of practical scientific workers before ii6oo, and nowhere was there a keener interest in the implications of the new astronomy, or a more earnest search for a satisfactory physical explanation of various features of the Copernican hypothesis. This active interest in the Copernican astronomy was due largely to the work and influence of THOMAS DIGGES, the most eminent astronomer and mathematician of Queen ELIZABETH'S reign.


With the changes in the social structure of China, medical aid to the poor has become a hot issue in our society. The authors analyze the current state of medical aid to the poor in China, disenss the difficulties in providing medical aid to the poor at present, and put forward the idea of providing medical aid to the poor through specifying aid funds, conducting fundraising in every way, establishing foundations, adopting a variety of aid patterns, obtaining the active cooperation of local hospitals, and coordinating aid organizations.


By the methods of literature,video observation and mathematical statistics,this paper analyzed the techniques of Chinese women's basketball team and Russian women's basketball Team in 2008 Beijing Olympic Games.Results were,Chinese women's basketball team was before Russian women's basketball Team in free throws,but inferior to Russian team in three-point shot,two-point shot,rebound,assist,tackling and so on.


Subcostal transversus abdominis plane (TAP) catheters have been reported to be an effective method of providing analgesia after upper abdominal surgery. We compared their analgesic efficacy with that of epidural analgesia after major upper abdominal surgery in a randomised controlled trial. Adult patients undergoing elective open hepatobiliary or renal surgery were randomly allocated to receive subcostal TAP catheters (n = 29) or epidural analgesia (n = 33), in addition to a standard postoperative analgesic regimen comprising of regular paracetamol and tramadol as required. The TAP group patients received bilateral subcostal TAP catheters and 1 mg.kg−1 bupivacaine 0.375% bilaterally every 8 h. The epidural group patients received an infusion of bupivacaine 0.125% with fentanyl 2 μg.ml−1. The primary outcome measure was visual analogue pain scores during coughing at 8, 24, 48 and 72 h after surgery. We found no significant differences in median (IQR [range]) visual analogue scores during coughing at 8 h between the TAP group (4.0 (2.3–6.0 [0–7.5])) and epidural group (4.0 (2.5–5.3) [0–8.5])) and at 72 h (2.0 (0.8–4.0 [0–5]) and 2.5 (1.0–5.0 [0–6]), respectively). Tramadol consumption was significantly greater in the TAP group (p = 0.002). Subcostal TAP catheter boluses may be an effective alternative to epidural infusions for providing postoperative analgesia after upper abdominal surgery.


ICAN is grateful for the opportunity to correct some of the main misunderstandings and misrepresentations that are contained in Mr Lundin's report. This is intended to help Sweden's parliament to make an informed decision based on an accurate understanding of the content of the United Nations Treaty on the Prohibition of Nuclear Weapons (TPNW) and of ICAN's policy positions. The English translations are unofficial except when the text referred to is included in Mr Lundin's English Executive Summary of his report.


Subgreenschist to amphibolite facies metavolcanic rocks found along the western flank of the Coast Plutonic Complex (western metamorphic belt) between Berners Bay and Endicott Arm, southeastern Alaska, are divided into three distinct sequences on the basis of age and the nature of interbedded metasedimentary rocks. These sequences crop out in linear belts, from west to east: the Gravina belt of Jurassic-Cretaceous age, the western Taku terrane of Permian to Triassic age, and the eastern Taku-Yukon-Tanana terrane of largely unknown age. Major, minor, trace element, and relict phenocryst chemistry are used to locate boundaries between the sequences and to provide clues to their origin. Variations in large ion lithophile element (LILE) and high field strength element (HFSE) abundances indicate that Gravina and eastern Taku magmas were derived through subduction-related processes. Pyroxene phenocryst compositions, LILE, light rare earth element, and HFSE enrichments in Gravina belt rocks are suggestive of high-K calc-alkaline to shoshonitic magmatism. Amphibolite facies metavolcanic rocks in the eastern Taku terrane are inferred to be island arc tholeiites. Western Taku metavolcanic rocks show little or no evidence of subduction-related genesis and resemble within-plate, possibly plume-related, basaltic magmas. Tectonic settings and magma sources inferred from metabasalt geochemistry and the associated stratigraphy of the three sequences are compatible with derivation of all the volcanic rocks in the western metamorphic belt and the Wrangellia terrane from a single Permian to Cretaceous arc complex. Initiation of arc tholeiite volcanism in the eastern Taku terrane possibly occurred during or prior to the Permian. Correlation of western Taku and Wrangellia rocks suggests a Triassic link between the Alexander and at least part of the Taku terrane, and nonsubduction-related basaltic volcanism prior to the Late Jurassic. Later rifting and/or changes in subduction geometry may have resulted in eruption of Gravina arc lavas into a marine basin, possibly floored by western Taku-Wrangellia rocks.


Radioactive Zr, Nb and Np were separated from each other by a continuous fractional extraction method. The extraction of Zr and Nb was carried out with 1 % TBP in chloroform from the 10N hydrochloric acid solution of irradiated U. Under these conditions, Zr, Nb and Np could be extracted continuously with the organic solution, while U and other F.P. remained in the aqueous solution. Finally, Zr in the organic solution was back-extracted with concentrated hydrochloric acid containing 1sim;2 drops of hydrofluoric acid. The method is convenient for the separation of Zr, Nb and Np from the F.P. The distribution ratios in the extraction system have also been obtained for a number of radioactive nuclides.


This essay is a fleshed-out version of a presentation to the 2011 COST Action workshop on the challenges of audience research. In it, I explore what I see as some overlooked problems in research ethics protocols, relating to the assumptions and models about our relations with research participants which resonate with wider "figures of the audience," which occur widely. In place of these, I outline a notion of "trust" as the proper goal of researcher-participants relations.


RCF is traditionally a very critical load condition for fatigue and, moreover, material defects (inclusions, inghomogeinities) play a significant role in determining the service life of materials exposed to the out-of-phase stresses which typically occur at the interface and below the surface of contacting bodies. In this paper we summarize the fatigue test results obtained for three different steels (a bearing, a gear and a railway wheel steels) that have been subjected to out-of-phase multiaxial fatigue tests simulationg RCF conditions in presence of small shallow precracks. The results show that the fatigue resistance domain is characterized by the presence of two different phenomena. In the region of σh < 0, tests simulating RCF for deep defects show a peculiar co-planar propagation driven by shear while in torsional tests the fatigue strength appears to be controlled by the onset of Mode I propagation. The experimental results have then been discussed adopting the Dang Van criterion showing that the dependence on crack size can be easily predicted in terms of Mode I and Mode III thresholds at the tip of the micro-cracks. INTRODUCTION Multiaxial fatigue has been the subject for the proposal of many criteria intended to predict fatigue strength (or fatigue life) under multiaxial conditions from a limited number of tests under uniaxial or torsional conditions. Among the different multiaxial loads, the out-of-phase (OOP) conditions that are typical of rolling contact fatigue (RCF), both for subsurface and surface failures, are in general the most detrimental for mechanical applications, with a severe reduction of the allowable fatigue shear strength respect to simple torsion. RCF is traditionally treated in terms of an allowable hertzian pressure [1], while the Dang Van criterion [2] has been the theory widely adopted for application to RCF [3, 4] because of its treatment of out-of-phase histories for the stress components and its simple definition of allowable shear stress as a linear function of the hydrostatic stress σh. However, the most demanding applications such as bearings are made of high strength steels, which are very sensitive to the presence of small defects and inclusions. Therefore it is important to consider the presence of defects for a significant strength prediction under RCF conditions.


The main purpose of this work is to develop a constitutive model for shape-memory devices, according to the phase transformation from austenite to martensite in NiTi Alloys and the relation with the stress-strain curve. First experimental testing is made to determine the mechanical behavior of the NiTi at several temperatures, and then a constitutive model is found according to the phase transformation behavior. The results show the microstructure evolution and its relation with the stress–strain curve. To conclude, a new constitutive model for the NiTi alloy has been developed which permits further analysis or simulation by finite element, which will be used in actuators for reconfigurable machines for flexible manufacture.


The number and the importance of Rich Internet Applications (RIA) have increased rapidly over the last years. At the same time, the quantity and impact of security vulnerabilities in such rich internet applications (RIA) have increasing as well. Since manual code reviews are time consuming, error prone and costly and it need skilled developers or programmers to review the manual source code review, the need for automated solutions has become evident. In this paper, we address the problem of application security vulnerable detection in Adobe Flex (Rich Internet Applications) platform in web 2.0 applications by means of static source code analysis. To this end, we present precise analysis targeted at the unique reference semantics commonly found in RIA based web applications or widgets (small applications which will run on fly i.e. drag and drop) developed in Adobe Flex Framework or Action Script 3.0. Moreover, we enhance the quality and quantity of the generated vulnerability reports.


By looking at the titles of the works by Luigi Meneghello, this article proposes a narratological analysis of his oeuvre, informed especially by Genette's theories of the paratext. Titles are here considered as textual spaces crucial for the interpretative process, since in them one aspect or detail of the text is invested with a metaphorical value. The heterolingual and/or polysemic titles of Meneghello's novels and essays establish a relation with the text that is programmatically ambiguous and open to interpretation. More precisely: 1. They are often intertextual, inspired by references to both Italian and foreign literature (ancient and modern, written and oral); even the author's personal memory is a fundamental intertext, together with stories told by friends and relatives; 2. They function as 'hooks' between the text and both the extratextual world and the intratextual reality (in the second case they contribute to reinforcing the internal consistency of the corpus); 3. They signal to the reader the author's poetics of multilingualism, either implicitly or explicitly, which uses in fact the Venetan dialect of Malo (the author's home village), courtly/literary Italian, Latin, and English, including authorial neologisms; 4. They reveal a major feature of Meneghello's writing, namely that desacralisation of officialdom, not only on a linguistic level, which Cesare Segre has interpreted using Bakhtin's category of 'carnivalization'. In their connotative stratification and interpretative ambiguity, Meneghello's titles therefore reflect the articulated textual constructions and the elaborate linguistic weaving that characterise his work. In short, they act as signals of the exegetic industriousness expected from the reader who decides to go beyond the cover and delve into the author's fictional universe.


There are many factors influencing the cost of municipal engineering. It is usually difficult and time consuming to predict the cost of municipal engineering. This paper proposes a two-phase method to predict the cost of municipal engineering by combining principal component analysis (PCA) and NARX neural network. In the first phase of the proposed method, PCA is used to analyze the correlations among involved factors based on the original data and extract key factors that influence the cost of municipal engineering. In the second phase, taking the key factors extracted by PCA as input and the unit area engineering cost as the output, a NARX neural network model is constructed based on the Bayesian regularization algorithm to predict the cost of municipal engineering. The experimental results show that the proposed method can predict the cost of municipal engineering fast and accurately, which shows that the proposed prediction method is feasible and effective.


AIMS
The aim of our study was to assess the two-dimensional carotid strain as an index of arterial stiffness in a population of patients without carotid atherosclerotic plaques.

METHODS AND RESULTS
Two-dimensional carotid strain, carotid intima-media thickness (CIMT), stiffness index (β), Peterson's elastic modulus, and distensibility coefficient were evaluated in 47 patients. For all patients, cardiovascular risk scores were calculated. Peak systolic circumferential strain was significantly correlated with conventional indices of arterial stiffness and with the CIMT. Peak systolic circumferential strain adjusted for pulse pressure was the only parameter that showed a significant difference between the three cardiovascular risk groups in which patients were classified. Two-dimensional carotid strain showed an excellent reproducibility.

CONCLUSION
The two-dimensional strain allows the assessment of carotid arterial mechanics. Probably the assessment of arterial stiffness allows a better risk stratification of patients.


Background: Patterned electrical neuromuscular stimulation (PENS) uses the electrical stimulation of sensory and motor nerves to achieve a skeletal muscle contraction using an electromyogram-derived functional pattern. PENS is used extensively for neuromuscular reeducation and treatment of muscle disuse atrophy. Purpose: To explore the effectiveness of PENS as applied to the quadriceps muscles on the vertical jump of an athletic population. Study Design: Experimental with control and repeated measures over time. Methods: Healthy college athletes (54 women, 75 men) were divided into 3 groups (control, n = 30; jump, n = 33; and jump with PENS, n = 63). There was no difference among groups' height and weight. Athletes performed a baseline standing vertical jump using a vertical jump system. The control group continued its normal daily activities with no jumping tasks included. The jump groups performed 3 sets of 12 repetitions with a 2-minute rest between sets at a frequency of 3 times per week. The PENS group did the jumping with the coordination of an electrical stimulation system. Vertical jump was retested after 6 weeks of intervention and 2 weeks after cessation. Results: A 3-way repeated measures analysis of variance for time (control, jump alone, jump with PENS) revealed a significant difference (P < 0.05) for time and an interaction between time and treatment, as well as a significant difference for the PENS group from baseline to posttest and for the jump group from posttest to follow-up jump. There was no significant difference between groups for the baseline vertical jump. Conclusions: This study demonstrated that 6 weeks of vertical jump training coordinated with PENS resulted in a greater increase than jumping only or control. This pattern of stimulation with PENS in combination with jump training may positively affect jumping.


Background: To assess to common type of perforations and their presentation, operative modalities, complications arising postoperatively at our hospital. Materials and Methods: It was an observational study; this study is based on analysis of 65 cases of benign cause of gastrointestinal perforation. Result: The time laps between onset of pain and presentation at the hospital was greater in the > 24 hours group with 58.5% of the patients presenting after 24 hours. Peptic ulcer perforation (32.31%) is the major cause of gastrointestinal perforation followed by appendicular (26.4%) tubercular (15.4%) and typhoid (10.8%).80% of cases had guarding /rigidity with 47.7% Patients presented with distention of abdomen.71% of cases had gas under the diaphragm with majority of them in peptic ulcer perforation and least appendicular perforation. Simple closure with Omental patch was the operative procedure done for all cases of peptic ulcer perforation and appendectomy for appendicular perforation. Half of patients with typhoid perforation closure in two layers and remaining half were treated with resection and end to end anastomosis. Most common Complication recorded in this study was SSI (16.9%) which was similar to that of respiratory infection/distress. Mortality in our study was 3.1% and was due to septicemia with other age group, delayed presentation to hospital and other associated co-morbidities being the additives factors. Conclusion: Finally surgical treatment is the most definitive treatment for perforative paternities patients and postoperative care remain extremely important in the better outcome of the patients.


Based on making use of MATLAB software,this paper presents the multi-goal optimal design with weighted factor about the two-grade helical cylindrical gear retarder and establishes the optimized mathematical model of the two-grade helical cylindrical gear retarder and makes sure restriction condition based on actual example.Compared with the traditional design methodologies,this approach provides a new design conception for large-scale gear transmission systems.


Children and adolescents of deployed soldiers require preventive and sometimes remedial service from school counselors, because deployment taxes coping skills and exacerbates normal developmental challenges. This article reviews the cultural and developmental context for children with deployed caregivers and outlines a ten session, hybrid psychoeducational-counseling group designed to increase student knowledge (e.g., emotional cycles of deployment), build student competencies (e.g., coping skills, mastery of developmental tasks), and promote a safe environment to express emotions with connected peers.


Abstract Several methods were compared for post‐plant incorporation of materials into a commercial potting medium to change the pH. Five days after treatment, surface application of limestone, Ca(OH)2 and Ca(NO3)2 did not significantly raise the pH. The pH of the top 5 cm of the medium was significantly raised by punching holes and surface applying lime. Pressurized injection of a limestone slurry resulted in consistent large increases of pH at every depth of the medium.


There is no greater joy or miracle than the creation of a life. But what does this milestone event mean for mum's oral health? Here, Charlotte Wake plays stork and delivers a bundle of information


It is generally acknowledged that a policy of agrarian reform involves much more than the mere redistribution of land to obtain an equitable system of production. A parallel and essential supporting range of complementary institutions usually need to be reorganised at the same time, concerned with credit, marketing, extension, and settlement, so that they can further rather than constrain and negate the reform. The old skewed land-holding structure, especially if involving latifundia estates, has probably contributed to a particular pattern of rural settlement that is quite inappropriate to cope with the more equitable distribution of land, unless large private estates are directly converted into state or multi-member farms. The beneficiaries of reform frequently need resettling on or near their newly-acquired land, and associated co-operative agencies for equipment, inputs, and marketing, together with programmes to provide basic social and commercial services, may well call for a nucleated form of settlement to be created.


Wireless devices are being increasingly deployed in digital homes to deliver demanding applications such as highquality streaming media. To avoid costly interference, they can use frequency-agile hardware to detect and utilize unoccupied wireless spectrum ranges. The challenge is how to manage spectrum among a variety of heterogeneous consumer devices efficiently without expensive control hardware or disrupting ongoing transmissions. We develop Jello, a distributed dynamic spectrum access system based on noncontiguous OFDMA to provide robust, high-bandwidth communication for consumer wireless devices. We implement a Jello prototype on a 7-node GNU Radio testbed. In this Jello demo, we will run three parallel transmissions with timevarying loads. We show that Jello can significantly increase spectrum utilization while reducing media disruption.


The scholar harassment also known by its English term bullying (frightened) is any form of physical, psychological, verbal abuse or produced between schools repeatedly along a determinate time the victim is subjected to a kind of methodical and systematic torture for the aggressor and the other schoolmates can assume the position of indifference, silence and complicity. From this perspective violence or abuse is a physical persecution and / or psychological behavior that makes the pupil against another, that chooses a victim of repeated attacks; this negative and hostile action, puts victims in positions that can hardly get out by their means, moreover violence is never justified and excused, all are victims and responsible because people do not mind this problem and sometimes the results are disastrous; for this reason this research aims to eradicate youth abuse "Bullying" and its impact on educational processes in students of the Colegio "Technical Trajano Naranjo Iturralde , through designing and implementing a guide that will allow authorities, teachers and Students take necessary corrective to this educational problem, which will make students live in a tranquility atmosphere within the educational institution and it is great importance because it becomes an effective tool for the development of good educational live.


Purpose Herpes zoster (HZ) is caused by the varicella-zoster virus (VZV), and 20% of healthy humans and 50% of people with immune dysfunction have a high probability of suffering from HZ. This study aimed to screen dynamic immune signatures and explore the potential mechanism during HZ progression. Patients and Methods Peripheral blood samples from 31 HZ patients and 32 age-sex-matched healthy controls were collected and analyzed. The protein levels and gene levels of toll-like receptors (TLRs) were detected in peripheral blood mononuclear cells (PBMCs) by flow cytometry and quantitative real-time PCR. Further, the characteristics of T cell subsets and cytokines were detected via a cytometric bead array. Results Compared to healthy controls, the mRNA levels of TLR2, TLR4, TLR7, and TLR9 mRNA in PBMCs were significantly increased in HZ patients. The protein level of TLR4 and TLR7 was significantly increased in HZ patients, but the levels of TLR2 and TLR9 were dramatically decreased. The CD3+ T cells were constant in HZ and healthy controls. CD4+ T cells were decreased in HZ patients, while CD8+ T cells were increased, resulting in an improved CD4+/CD8+ T cells ratio. Further, it was found that Th2 and Th17 were not changed, but the decreased Th1 and upregulated Treg cells were found in HZ. The Th1/Th2 and Th17/Treg ratios were significantly decreased. Last, the levels of IL-6, IL-10, and IFN-γ were significantly increased, but IL-2, IL-4, and IL-17A had no significant changes. Conclusion The dysfunction of host's lymphocytes and activation of TLRs in PBMCs were the important mechanism in varicella-zoster virus induced herpes zoster. TLRs might be the core targets for the therapy drug development in treating HZ.


Gender identity refers to an innate and deeply felt psychological identification as a female, male, or some other non-binary gender. Gender identity may be congruent or incongruent with the sex assigned at birth. Gender dysphoria refers to the discomfort or distress that gender incongruence may cause. If the distress is clinically significant, the individual may need gender-affirming treatment. The literature is sparse with respect to the etiology, prevalence, and long-term outcomes. The overall aim of this thesis is to further our understanding of gender dysphoria regarding neurobiological characteristics, epidemiology, and health following gender-affirming treatment. Study I explored the hypothesis that cerebral activation in hormone-naïve transgender women (assigned males at birth) on exposure to odorous steroids would be in line with their gender identity, and thus similar to cisgender women but different to cisgender men. Gender dysphoric transgender women demonstrated a cerebral activation pattern that corresponded predominately to that of cisgender females, but also some cisgender male characteristics. Study II described the prevalence and changes in incidence of applications for change of legal gender and applications to reverse the procedure during 19602010. The incidence of gender dysphoria increased three times for individuals assigned male at birth, and two and half time times for individuals assigned female at birth. The increase accelerated after 2001. The rate of reversal applications was 2.2% with a significant decline over the study period. Study III explored long-term mortality and psychiatric morbidity after sex reassignment in a nation-wide cohort study (1973-2003). The overall mortality rate was higher in individuals who had undergone legal and medical transition compared with the general population for the whole period, but not for the period 1989-2003. Probands had more psychiatric inpatient care and suicide attempts compared with controls for the whole period as well as the period 1989-2003 (with the exception of suicide attempts). This study cannot determine the effectiveness of gender-affirming medical intervention, but the results highlight the need for better health care following gender transition. Study IV examined outcomes following legal and surgical gender transition, mean (SD) follow-up time 7.2 (7.3) years, by means of individual interviews with 16 men (assigned female at birth) and 49 women (assigned male at birth). The vast majority of the participants felt gender congruent and global clinically improved, but the prevalence of psychiatric morbidity and suicide attempts was high. Childhood adversities and adult stressful life events were common. Being born abroad, childhood adversities, and not being accepted by others in assigned gender predicted current psychiatric morbidity.


The problem of secret key agreement by public discussion is studied under a general multiterminal network, where each user can both send and receive over a private channel. Single-letter upper and lower bounds are for the maximum achievable key rate. The bounds are shown to match for a large class of private channels. A counter-example shows that the bounds do not match in general, and a better cooperative scheme can narrow the gap.


DEVICE FOR QUICK COUPLING BETWEEN APPARATUS AND DENTISTRY ELEMENT ON WHICH IT IS CONNECTED IN USE BY THE PRACTITIONER CHARACTERIZED IN THAT IT CONTAINS ESSENTIALLY: aA COLLAR 6 TRUNCATED AT LEAST 7 SEGMENT AND SOLIDARITY OF THE UNIT OF DENTISTRY; bA RING 12 SOLIDARITY THAT ELEMENT WHICH THE END 14 is recessed ACCORDING TO FEMALE FORM IN WHICH CAN REGISTER PROFILE OF THAT cOLLAR THE CONNECTION IS OBTAINED BY POSITIONING THE cOLLAR 6 AFTER ENTRY IN SUCH RECESS 14 IN THROAT 15 RING TWIST ON THE cOLLAR AND RING. APPLICATION OF dENTISTRY CONNECTING COMPONENTS.


Summary

Percentage cover of game trails is discussed as a possible measure of total habitat utilisation by larger mammals and a technique for its measurement is described. Game trail cover in Tsavo National Park (East) at Voi has been analysed in two areas, woodland and grassland. Of these the woodland had the higher trail cover (10.69%) and grassland the lower (7.57%). The interpretation of these results is discussed.


: This paper aims to explore the impact of mobile devices on Indonesian men's sexual communication. Gay men need to express their homosexual feelings despite resistance from society. The paper is based on qualitative and quantitative research used to describe and assess the current use of social media in Indonesia, paying specific attention to how it is transforming sexual negotiations among gay men and other MSM. Its objective is to gain an understanding of how online social interactions are transforming gay and MSM Indonesians' experience of sexuality, identity and community. The findings demonstrate how the participants are very committed to social media as shown by the degree of openness in declaring their sexual orientation. Specifically, this research discovered that social media is used mostly by youths to find partners and to connect to other gay men as a means to construct a sense of community and belonging. Interestingly, one of the results also revealed the favourable reception of gay men toward women when it comes to sexual relations.


This paper analyzes the rotor magnetic potential distribution under normal and inter-turn short circuit condition,and obtains the conclusion that the 1/2th harmonic current of the stator winding and 3/2th harmonic current of the rotor winding are both born from the second harmonic current of the stator through the further analysis of harmonic under inter-turn short circuit fault.At the same time,this paper analyzes the stator current,stator voltage,rotor current,rotor voltage,the active and reactive power,which are affected by the inter-turn short circuit in theory.The analysis is verified by the simulation through the MATLAB/SIMULINK,and it will lay the foundation for choosing characteristic quantity that can determine the rotor winding inter-turn short circuit fault.


Human uterine stone formation is an exceedingly rare condition and to our knowledge only two previous case reports has been published on uterine stones. Uterine calcification occurs in many animal species related to the formation of a protective shell for the developing embryo 1 and human endometrial calcification has been rarely associated with some benign and malignant conditions in the form of Psammoma bodies. We present here a rare case of uterine stone in an 8 year old female child.


Whether burning-out of the gland, i.e. progressive parenchymal destruction, leads to pain decrease has been repeatedly debated. 8,9 The group of Ammann has claimed that pain decreases with increasing duration of the disease.3,lo,1l In one long-term study, 85% of 145 patients with chronic pancreatitis felt no more pain after 4.5 years (median) duration of the disease.3 The reports from Zurich are at variance with the studies from Japan and Germany. Miyake et al. 6 found that only 48.2% of the patients with chronic pancre atitis became free of pain within 5 years, and 66-73% after more than 5 years. That meant that every third or fourth patient still suffered from relapsing pain attacks even after a longer observation time. Our group7 reported that the incidence of relapsing pain attacks decreased during the observation period, but more than half of the patients (53%) still suffered from relapsing pain attacks even after more than 10 years of observation (Table 15.1).7 At present, the course of pain in alcoholic and idiopathic chronic pancreatitis remains unclarified. Layer et al. l2 investigated a group of patients with idio pathic chronic pancreatitis who had never consumed alcoholic beverages during their life time. They found that patients with early-onset pancreatitis (onset at 35 years) have a mild and often painless course. Both forms differ from alcoholic pancreatitis in the equal gender distribution and a much slower rate of calcification. In contrast, our group13 found that the course of pain is the same in alcohol- and


This research purpose for describes how Liquifed Petroleum Gas 3 kg distribution controlling in Padang City based from Human Resources and Enery Ministry Regulation No. 26 Tahun 2009 about Liquifed Petroleum Gas 3 kg distribution. Liquifed Petroleum Gas 3 kg is fuel which is having speciality because specific condition like a user/using, packaging, volume and/or the price which have to giving the subsidy. The Liquifed Petroleum Gas 3 kg distribution controlling in Padang City doing by Liquifed Petroleum Gas 3 kg distribution Controlling and Founding Team based on Document Desicion of Region Secretary Padang City No 800.IV.2294.17/Dg 2017. This research using T. Hani Handoko teory about Controlling Phases. This research using qualitative descriptive approach, Data was collected by interview and documentation. The test validity of data found using source triangulation techiques. The result of this research declaire that controlling of distribution Liquifed Petroleum gas 3 kg in Padang City have not effective, it can be found the distribution facilities not having Commercial Business Licence, distribution facilites that sell above the highest retail prices, distribution facilities that do not submit reports on the realization of distribution, implementation of controlling by monitoring team that does not go according to the schedule and initial plan of controlling.


Dr. Hugh M. Morris, Consulting Radiologist to the Salford Group of Hospitals, died in the Salford Royal Hospital on October 2, 1959. Hugh Morris was born at Glenarm in Northern Ireland in 1898. From the Christian Brothers School at Omagh he went to Queen's University, Belfast, with a County Scholarship and graduated in 1921.


In this paper,the research progress of conical spray and internal flow of conical spray injector was analyzed,and the model of multiphase flow with cavitation was established and testified with three-dimensional computational fluid dynamics(CFD) program.Based on the testified model,the internal flow characteristics of the conical spray injector were simulated and analyzed.The simulation results show that the dissymmetrical cavitation occurs in the inlet of the injector orifice and extends to the outlet step by step,which leads to negative effects on fuel atomization.


The development of agriculture in recent decades has in the main been the same in Norway as elsewhere in western Europe. The agricultural population and the number of farms has rapidly diminished; state regulation measures have been increasing and, around the primary production, a highly centralized industry taking care of the processing of agricultural products and the producing of the means of production has grown. This development has had such serious effects on the living conditions of the population both in agriculture and in other sectors of society, that all serious research on this subject is welcome. The scope of the changes and the problems makes it easy to understand Almais's starting principle to make 'an analysis in width, not in depth' (p. 7), although this has its weaknesses too.


The Bloch–Beilinson–Murre conjectures predict the existence of a descending filtration on Chow groups of smooth projective varieties which is functorial with respect to the action of correspondences and whose graded parts depend solely on the topology, that is, the cohomology, of smooth projective varieties. In this paper, given a smooth projective complex variety X, we wish to explore, at the cost of having to assume general conjectures about algebraic cycles, how the coniveau filtration on the cohomology of X has an incidence on the Chow groups of X. However, by keeping such assumptions minimal, we are able to prove some of these conjectures either in low‐dimensional cases or when a variety is known to have small Chow groups. For instance, we give a new example of a 4‐fold of general type with a trivial Chow group of zero‐cycles and we prove Murre's conjectures for 3‐folds dominated by a product of curves, for 3‐folds rationally dominated by the product of three curves, for rationally connected 4‐folds and for complete intersections of low degree. The BBM conjectures are closely related to Kimura–O'Sullivan's notion of finite‐dimensionality. Assuming the standard conjectures on algebraic cycles, the former is known to imply the latter. We show that the missing ingredient for finite‐dimensionality to imply the BBM conjectures is the coincidence of a certain niveau filtration with the coniveau filtration on Chow groups.


In this work we present the mathematical analysis of a system able to describe the biological chemotaxis phenomena. The proposed model is a modification of the classical Keller Segel model and its subsequent developments, which, in many cases, have been developed to obtain models that prevent the non-physical blow up of solutions.


The sensing material for CO2 is prepared with nano powders of BaTiO3,which are prepared by the precipitation method and doped with the CeO-AgNO3 by the semiconductor ceramic technology.The electrodes are fabricated based on the CaCO3 and RuO2.The NiCr thread is used as the heater.While the sensors are heated up to the temperature range of 400 ℃ to 450 ℃,the responses to CO2 are measured.When the volume ratio of CO2 is ranging from 100×10-6 to 2 000×10-6,the sensor's feature resistance is decreased from 600 kΩ to 150 kΩ,which shows good full logarithm relationship.The temperature and humidity characteristics of the sensing component are also measured.To improve the measurement correctness of sensors,the compensation technique on environmental temperature and humidity should be considered.


Adoptee discourse and its literature have garnered the critical interest and attention very recently under the numerous approaches to transnational,...


The past decade has witnessed a dramatic translation of basic immunology concepts into successful clinical applications for the treatment of rheumatoid arthritis and other autoimmune diseases by immunotherapy. This evolution has been spearheaded by the widespread success of therapies targeting individual cytokine pathways, in particular TNF-a, but also IL-1 and now also IL-6. These therapies have shown an excellent level of efficacy in a majority of patients, many refractory to conventional therapeutical approaches, thus providing new hope and a major advancement in therapeutical options. This progress comes at a cost, not just financial, but particularly in terms of ease of administration, tolerability, and safety. It would be difficult, however, to argue against the fact that the cost=benefit ratio has been favorable to date. The widespread application of these first-generation biologics has had two main consequences:


A study was conducted in which 30 children ranging from 9 years to 17 years were studied, these children were working in low social class hotels and restaurants in the city. The aim of the study was to assess the social and emotional status and the working condition of these children. The data was collected by interview and personal observation of the authors. The data collected, suggested that threse children were working in poor conditions with low wages. their working hours were long with no leisure. There was no health or educational facilities. These children were growing up in an enviroment which was detrimental to physical and metnal health of these individuals. Majority were forced to work due to poverty and were either the sole eaner of their family or unempolyed parents.


The article deals with some text elements of Kalmyk heroic tales, the latter being compared to samples of epic genres of other peoples, mainly those of Siberia's Turkic populations. Recent publications of Kalmyk heroic tales provide new opportunities for comparing the fabulous texts with songs (chapters) of the Kalmyk heroic epic of Jangar and studying the interaction between epic and fairy-tale forms. There are distinct 1 Исследование проведено в рамках государственной субсидии — проект «Фольклор монголоязычных народов: тексты и исследования» (регистрационный номер АААА-А17-117030910099-8).


Objective To study anatomic land marksers and orientation methodology in the cerebellopontine angle through retrolabyrinthine approach under an endoscope. Methods In 10 cadaveric specimens (20 sides),endoscopic surgery via retrolabyrinthine approach was simulated. The anatomic features of the cerebellopontine angle were examined and measured. Results Measuring from the posterior margin of posterior semicircular canal on plane of lateral semicircular canal,the distance was 15.89 ± 1.61 mm to the posterior margin of internal acoustic meatus,27.43 ± 3.25 mm to the inferior margin of trigeminal nerve and 19.39 ± 2.57 mm to the upper margin of glossopharyngeal nerve. The angle between the line connecting the posterior margin of posterior semicircular canal with the posterior margin of internal acoustic meatus and the line connecting the posterior margin of posterior semicircular canal with the upper margin of glossopharyngeal nerve,was 16.78 ± 2.06°. The angle between the line connecting the posterior margin of posterior semicircular canal with the posterior margin of internal acoustic meatus and the line connecting the inferior margin of trigeminal nerve was 16.25 ± 2.88°. Conclusion Endoscopic surgery in the cerebellopontine angle via a retrolabyrinthine approach has advantages of minimal invasiveness,satisfactory exposure and multi -angle visualization and provides an efficient utility in microsurgery.


During the study of fish parasites in the Serbian section of the Danube River in 2003, a new Trematoda species for ichthyofauna of Serbia has been detected. It is, at the same time, the first finding of larvae of Metagonimus yokogawai in Serbia, as adult forms have been observed from mallard Anas platyrhynchus (L.), previously. Metacercariae of M. yokogawai have been identified on the scales of chub Leuciscus cephalus (L.), barbel Barbus barbus (L.), bleak Alburnus alburnus (L.), pikeperch Sander lucioperca (L.) and rudd Scardinius erythrophthalmus (L.) in the Serbian part of Danube River. The particular risk, beside the possible negative influence of spreading on fish and other host populations (some aquatic snails, fish-eating birds and some mammals), is the potential spreading of the parasitic disease in humans - Metagonimosis.


Human sexuality is biopsychosocial in nature. It is discussed in the literature as a dynamic process and the right of all individuals (Sakellariou and Algado, 2006). Irwin (1997) compared sexual health to culture, and discussed how changes in sexuality parallel changes in culture over time. Sexuality is not just about 'having sex' but includes making relationships, self-esteem, tactile expressions and the need for intimacy and closeness. These issues are important in the lives of the general population, and also therefore, of the clients seen by health-care professionals (Wells, 2002; Barnes and Ward, 2005).


Some experts in our country call for an executive pre-trial procedure for antimonopoly civil litigations.However review of abroad developments in legislation and internal development of judicial practice reveal that both of them do not support such a position,which is also disarmed by applying the common jurisprudence,the requirement of judicial efficiency and the realization of legislation purpose in China.Meanwhile the reasons for the position is not firmly standed.


the crucifixion within an apocalyptic battle between God and Satan that culminates in the movement from crucifixion to descent into the hell to resurrection. Anchored by an avalanche of biblical references, rereadings of Anselm in light of Athanasius' substitutionary views, and a persistent linking of scholarly and biblical insights to contemporary horrors, Rutledge moves towards her conclusion that the God of the cross, who descended into hell, is bent on dikaiosis, which she translates as 'rectification'. In that light, the radicality of Paul's preaching of Christ the Victor becomes clear: that the world is loved by God means it must be made right, and that rectification costs God dearly. While Rutledge's contributions to Christian thinking and preaching about the cross are many, her approach can at times be off-putting. Her enthusiastic commitment to the absolute uniqueness of Christianity and the irreligiosity of the cross takes her perilously close to supersessionism when comparing Christianity to other religions. In addition, her mission to reassert the life-giving meaning of Christ's crucifixion leads at times to collapsing diverse viewpoints from feminists and others who critique interpretations and applications of cross-centred theologies. And Rutledge's portrayal of churchgoers as addicted to uplift and allergic to serious engagement with suffering, death and that which conquers death seems to disparage the very lay readers she hopes will pick up her book. Even with these liabilities, Rutledge's The Crucifixion will endure as a major contribution to Christian proclamation of Christ crucified. Deanna A. Thompson Hamline University, St Paul, MN 55104


In this Perspective, autopsy results and literature are presented supporting the hypothesis that neutrophil extracellular traps (NETs) may contribute to organ damage and mortality in COVID-19. If correct, existing drugs that target NETs, although unspecific, may benefit COVID-19 patients.


Brazil is structurally marked by slavery and patriar-chalism. It is very difficult to understand the complexity of our formation without an intersecting look between slave relations, gender and color / race relations. In spite of this observation, the Social History of slavery in Brazil abandoned or minimized the concept of patriarchalism in the approaches of its research, opting for other theoretical concepts, more sensitive to the cultures and the symbolic constructions of historical agents. This article proposes the resumption of Gilberto Freyre's patriarchalism, and its possible connections with the concept of gender, bringing it to the center of slavery. That is, it proposes gender as structural in slave relations, and calls on the histori-ans and historians of slavery to debate, in the sense that patriarchalism/gender is definitely considered indispensable to understand slavery.


From November the 12th though November the 13 2012 on the premises of the Volgograd State Social Pedagogical University there took place the 29th session of the Scientific Council of the Russian Academy of Education for the problematics of history of education and science of pedagogy on the topic: "The teaching of the historical and pedagogical disciplines in institutions of higher and professional education: content and contemporary approaches ".


In this paper we consider the generalized shift operator, generated by the Gegenbauer differential operator $$ G =\left(x^2-1\right)^{\frac{1}{2}-\lambda} \frac{d}{dx} \left(x^2-1\right)^{\lambda+\frac{1}{2}}\frac{d}{dx}. $$ Maximal function ($ G- $ maximal function), generated by the Gegenbauer differential operator $ G $ is investigated. The $ L_{p,\lambda} $ -boundedness for the $ G- $ maximal function is obtained. The concept of potential of Riesz-Gegenbauer is introduced and for it the theorem of Sobolev type is proved.


In direct steam generation(DSG) parabolic trough solar generation plants,there used many receivers.In order to solve the complex configuration and high cost of the sealing device in the medium solar receiver,a novel configuration and an independent-design sealing device was developed.By using thermal-stress coupling function of the large finite element method software ABAQUS,a numerical simulation of temperature field and stress field of flange plate in working was made.The analysis shows that,the maximum stress change appears in the heat affected zone of the flange's center and it has main influence on surface crack of flange plate and the maximum stress is less than the allowable stress 235 MPa of the material,which is in the reliable range.


One of the major contributions in the field of Ottoman medicine was the establishment of a hospital institution called darüşşifa. Basically, this hospital was developed in the early 15th century with the aim of promoting medical activities through practice in institutions as well as offering public health services free of charge. The establishment of this hospital has also restored the glorious tradition of the hospital that was once achieved in Islamic civilization in previous eras. Thus, this study was conducted to identify the concept and history of the establishment of hospitals in the Ottoman Empire from the 15th century to the 16th century. This study uses a qualitative method with a historical study design approach based on various authoritative sources and then analyzed using text analysis and deductive methods. The findings of this study clearly show that the hospital (darüşşifa) in the Ottoman Empire was a charitable institution that offered a combination of education to medical students as well as free medical services to the general public. It is usually built either by the government or the palace in a complex (kulliye) located in major cities such as Bursa, Edirne, Istanbul and Manisa. The hospital building has unique features such as providing holistic treatment including medical and spiritual treatment, having a variety of medical functions and expertise, complete facilities and a conducive and eco-friendly environment. With the establishment of this hospital, the Ottoman Empire was able to strengthen the field of medical science, expand access of health and education facilities to the whole community as well as able to achieve sustainable development in the country successfully.


Objective: To analyze the stress distribution of root and post-core after different diameters and lengths of split post-core crown molar teeth by using three-dimension(3D) finite element,and study the influence of diameter and length on the repair teeth.Methods: With spiral CT scans and the techniques of medical image transmission and transcription,maxillary first molar three-dimensional finite element model was established with different diameters and lengths of split post-core crown.Compare the stress distribution of root and post-core after split post-core crown molar teeth in different loads.Results: Reducing the length of post-core can make the stress peak of root and nuclear stress peak decreased;with the increase of post-core diameter,the stress peak of root will be increased,while stress of post-core will be decreased with its diameter increases.Conclusion: The appropriate reduction in the length and diameter of post-core will improve the success rate of restoration.


In order to meet both safety and efficiency requirements of wireless power transfer (WPT) systems, reducing electromagnetic field (EMF) leakage and improving efficiency are critical factors in the implementation of systems. Recently, metamaterials have exhibited the ability to control the electromagnetic wave propagation. In this paper, the WPT system integrating with near-field mu-near-zero (NF-MNZ) and mu-negative permeability (MNG) metamaterials is proposed to control EMF leakage below a certain level and improve transfer efficiency. The NF-MNZ and the MNG metamaterials are placed on both sides and in the middle of the WPT system, respectively. In addition, the property of the NF-MNZ metamaterial slab and its working principle on the WPT system are analyzed. The shielding performance of the NF-MNZ metamaterial are evaluated via numerical simulation and experimental investigation. Finally, the efficiency and the magnetic field strength of the WPT system with two different types of metamaterials have been investigated by the experimental measurements. At the transfer distance of 40 cm, the experimental results show that the efficiency of the WPT system is increased by 12.06% and the magnetic field strength is reduced by 62.09%.


Some call it the race of the century. The Defense Advanced Research Projects Agency DARPA has a rich history of pursuing innovative technical ideas that lead to capabilities never before dreamed possible. DARPA's past projects resulted in the ARPANET which led to the Internet , stealth, and the Predator and Global Hawk unmanned aerial vehicles. In 2003, Dr. Tony Tether, DARPA Director, believed the time was right to push autonomous ground vehicle technology. The thinking was that if such vehicles were possible, they could be used in dangerous military missions and save the lives of young American men and women in uniform. At that time, many experts believed fully autonomous ground vehicles that could travel great distances at speeds important to military operations were not possible within any near-term timeline. Thus, Dr. Tether created the DARPA Grand Challenge as an experiment to accelerate autonomous ground vehicle technology. The expectation was that only a few people would respond, but the Grand Challenge awakened a new surge of creativity among thousands from the United States and other countries. The first Grand Challenge was held in March 2004 and, from an initial field of 106 applicants, 15 teams competed in the final event. The best vehicle managed to travel 5% of the route before failing. It was clear then that the challenge was indeed "grand." At the 2004 closing ceremony, DARPA announced another competition and doubled the prize to $2 million. October 2005 was chosen for the second competition—a mere 18 months after the first event. America's innovators again rolled up their sleeves and got to work. Eighteen months is not a long time to create technology that may change the world. DARPA received 197 applications to compete in the 2005 event, and each of the 23 teams that made it to the final event had a vehicle that proved, through a series of difficult qualifying trials, to be better than the best vehicle in the 2004 race. The 2005 course was tough: 132 miles of difficult desert roads across Nevada that contained a mixture of featureless terrain, dust, global positioning system drop-outs, sharp turns, narrow openings, bridges, railroad overpasses, long tunnels, obstacles, and a narrow winding mountain road with a 200-foot drop-off. The actual route was kept secret until 2 hours before the start. Remarkably, five teams finished the course, four of them under the 10-hour limit and within 37 minutes of the winning time of Stanford's "Stanley" at 6 hours and 53 minutes and an average speed of 19.2 miles per hour. In another first for autonomous vehicle operations, "TerraMax" finished the course on the second day after remaining parked overnight in autonomous mode. The vehicles that did not finish the course suffered mechanical, system, or software problems. In the end, 22 of the 23 teams traveled farther than the best vehicle did in 2004. By all accounts, Grand Challenge 2005 was a spectacular success. The primary reason for the success of the Grand Challenge lies with the teams—the students, engineers, scientists, and backyard mechanics—all inventors who brought fresh ideas to solve a very difficult technical problem. They were individuals, but learned to work together in teams. Unlike other prize events, the DARPA Grand Challenge set a specific date for the competition, and all the teams spent countless long hours overcoming setbacks to be there for the final event. The teams accelerated autonomous ground ve• • • • • • • • • • • • • • • • •


The Bureau of Mines is currently developing methods for reclaiming the metal and mineral values contained in unburned urban refuse. One important phase of the research deals with recovering plastics from shredded refuse using an electrodynamic process. The results of this study have indicated that mixed plastic concentrates analyzing 99.4 percent plastic can be consistently recovered from the light material fraction of shredded refuse, leaving a mixed paper fraction analyzing 99.9 percent paper. Recovery of the plastics exceeds 99 percent.


The post—Cold War surge in so-called tribal conflict is shown here to be the continuation of a trend that began in the 1960s. The main issue of the fifty most serious current ethnopolitical conflicts is contention for state power among communal groups in the immediate aftermath of state formation, revolution, and efforts to democratize autocratic regimes. The end of the Cold War contributed to the long-term trend mainly by increasing the number of states with such power transitions. Communal conflicts across fault lines between civilizations and religious traditions are more intense than others but have not increased in relative frequency or severity since the end of the Cold War. Nor is there a strong global force leading toward the further fragmentation of the state system: since 1989 no serious new secessionist conflicts have begun outside the Soviet and Yugoslav successor states, and in 1993–94 the regional trend is toward accommodation. The most protracted and deadly ethnopolitical conflicts are likely to occur in poor, weak, heterogenous states like those of Africa. They will continue to pose severe humanitarian problems but are foreseeable and, in principle, are capable of being contained and transformed through constructive regional and international action. Six general international strategies to restrain emerging ethnopolitical conflicts are identified.


The development of science and technology, especially the major events, are not only affected by purely technical factors, but also bound up with many irrational social factors. Space activities, of significant importance in science and technology as well as in the political field, are the combination of inner and outer factors, which reflect comprehensive strength of the nation. With the purpose of analyzing the influence of social construction on technological development, the author focuses on the case of Dongfanghong-I, making explanation and analysis of the influence of politics propaganda on the research and development of the satellite in the historical context. The paper concentrates on three aspects: the proposal of propaganda function of Dongfanghong-I, the transition of the tasks of the satellite and its particular propaganda functions; specifically in terms of how political propaganda affects satellite technology such as observable spheroid, orbit, electronic music generator and overload switch.


We investigate the switching feeding behavior of predators in the context of one single prey population, which is disease affected. We consider the case of hunting indiscriminately both types of prey, when the infected prey causes no harm to their predators, but assume also in another model that feeding on the infected individuals has a negative return on the predators. Some counterintuitive results are obtained and discussed.


The concept of the energy internet was put forward and gradually became a focus in "the Third Industrial Revolution". Through energy internet, energy management will be changed from traditional centralized management to decentralized one, and the power network can be shared in the whole word. The characteristics of decentralization, transparency, contract execution automation, traceability, and openness of blockchain technology are applicable to the development and application of energy internet. This article summarizes the relevant knowledge of blockchain technology and the current application in various aspects of energy systems. Finally, some existing problems of blockchain applications in energy systems are discussed.


This review is devoted to occlusion therapy which is used to improve visual functions in children with retina affected by the treatment of retinoblastoma. There are listed the most used eye patch covering regimes, effectiveness and complications of such method. Overall, in most cases occlusion therapy provides improving of visual functions in this group of patients. Key words: occlusion therapy, retinoblastoma, eye patch, visual function in children.


We analyze batch-scheduling problems that arise in connection with certain industrial applications. The models concern processing on a single max-batch machine with the additional feature that the tasks of the same batch have to be compatible. Compatibility is a symmetric binary relation – the compatible pairs are described with an undirected "compatibility graph", which is often an interval graph according to some natural practical conditions that we present. We consider several models with varying batch capacities, processing times or compatibility graphs and summarize all known results.


We prepared high-quality monolayer Langmuir-Blodgett films using a novel molecule C37H40N404 synthesized by us. This molecule is the long-chain alkyl derivative which has dinitrobenzene moiety (acceptor subunit) and dihydrophenazine (donor subunit) bridged by a methylene group with constant distance and bond angle. It behaves as unimolecular device with the control of the potential between donor and acceptor subunits. We transferred the monolayer film onto a mica plate and succeeded in getting molecular images by AFM. Furthermore the monolayer was transferred onto Au (111) and manometer-scale rectifying or semiconducting characteristics were successfully obtained by using AFM I-V technique.


As a consequence of increased government efforts to reduce local Norwegian CO_2-emissions the development of small distributed generators have increased. This development is assumed to continue, b ...


The LHC high luminosity project envisages the use of the crabbing technique for increasing and levelling the LHC luminosity. Double Quarter Wave (DQW) resonators are compact cavities especially designed to meet the technical and performance requirements for LHC beam crabbing. Two DQW crab cavities are under fabrication and will be tested with beam in the Super Proton Synchrotron (SPS) at CERN by 2017. This paper describes the design and prototyping of the DQW crab cavities for the SPS test.


The aim of this study was to determine the effect of electric pulses on the structural and functional condition of rabbit oocytes. The New Zealand White female rabbits at 3-5 months of age and at 3-4 kg body weight served as oocyte donors. Oocytes after flushing from the oviducts were placed between two electrodes in an electroporation chamber which was filled with a dielectric solution. Following a short incubation in B2 medium, oocytes were subjected to an electric pulse released by an electrical pulse generator. Oocytes were then incubated in 500 µl of B2 medium supplemented with 20% foetal calf serum (FCS) at 38°C in an atmosphere of 5% CO 2 in air. Oocytes were cultured until the morula/blastocyst stage (approx. 72 h). The experiment was conducted using 430 oocytes obtained post mortem. In vitro cultured oocytes not subjected to an electric pulse were the control. Each group was subdivided into replications according to electric current intensity. The analysis of experimental variants shows that in the first variant all embryos developed to the morula stage but only 10% of them continued to develop to the blastocyst stage. In the second variant we observed that 5-10% of oocytes developed to the blastocyst stage after treatment with 2.0 and 2.5 kV/cm pulse but in the group of 1.0 kV/cm pulse 35% of oocytes developed only to the 2-12 b stage. In the third variant only 1 oocyte (5%) continued to develop to the blastocyst stage, but in the fourth variant oocyte development stopped at the morula stage. In the fifth variant, called an "extreme" one, oocytes stopped to develop at the stage of 2-12 b (about 25%) and the percentage of degenerated oocytes dramatically increased (about 60%).


Background : Patients with diffuse large B-cell lymphoma (DLBCL) not cured by first line R-CHOP chemotherapy or second line high-dose chemotherapy with autologous stem cell rescue have a poor prognosis and represent a clear unmet medical need. Lenalidomide (Revlimid®), an immunomodulatory drug, has activity in hematological malignancies including relapsed/refractory multiple myeloma, chronic lymphocytic leukemia and cutaneous T-cell lymphoma.

Aim: To determine the activity and safety of lenalidomide monotherapy in relapsed/refractory DLBCL.

Methods: Patients with relapsed/refractory DLBCL with measurable disease after at least 1 prior treatment regimen were eligible. Patients received 25 mg lenalidomide orally once daily on Days 1–21 every 28 days and continued therapy for 52 weeks as tolerated or until disease progression. Response and progression were evaluated using the IWLRC methodology. Univariate analyses using Fisher's exact test was conducted to investigate and characterize associations of prognostic variables with response.

Results : Twenty-six patients with DLBCL lymphoma were enrolled. The median age was 66 (45–86) and 13 were female. Median time from diagnosis to lenalidomide was 2.4 (0.5–12) years and median number of prior treatment regimens was 3 (1–6). Three patients (12%) exhibited an objective complete response (1 complete response (CR) and 2 complete responses unconfirmed (CRu)). Two patients had a partial response (PR) for an overall response rate of 19% and 7 had stable disease (SD). Response to lenalidomide was associated with low disease burden (33% for 4.2 months (> 3.6 - > 6.2). Eight patients (31%) required at least one dose reduction with a median time to first dose reduction of 1.8 months (0.4–2.9). One patient each (4%) had Grade 4 anemia, cauda equinine syndrome, febrile neutropenia, intermittent rash, lymphopenia, neutropenia, pneumonitis and thrombocytopenia. Most common Grade 3 adverse events were neutropenia (19%), thrombocytopenia (15%) and leukopenia (12%).

Conclusion : The prognostic factors of tumor burden and time from last dose of rituximab appear to identify relapsed/refractory DLBCL patients with a high likelihood of response to lenalidomide oral monotherapy.


Imagine my surprise at being challenged to a duel (a habit I had thought reserved for miffed aristocrats) in these pages by a well-regarded cultural studies scholar whom, to my knowledge, I have never met. In her response to my article ''The Matrix and Critical Theory's Desertion of the Real,'' Jennifer Slack notes errors and omissions in my reading of contemporary theorists (particularly Deleuze, Althusser, and Hall). She objects to my setting aside psychoanalytic theories of the Real and its relationship to agency in favor of an experiential definition. She is irked that I read the films primarily as theoretical allegory and questions whether my article is an exemplar of cultural studies. Her primary target, however, is what she claims to be my careerism and lack of scholarly integrity. She condemns my article for having too many footnotes that she claims obscure my nefarious motives from those who might find my argument*that the poststructuralist discursive turn in critical communication studies has substantially abdicated real grounds for political judgment and transformative human agency*persuasive. I must say that my defense of historical materialism, undertaken in all earnestness, has never eased my career path. Slack's scrutiny of my footnotes reminds me of the painstaking, politically motivated University of Colorado committee who combed Ward Churchill's footnotes in order to discredit him, resulting in his termination. I searched Professor Slack's work for the profound disagreements that could explain such a vituperative response. Slack is something of a postmodernist, and she prefers articulation theory to a Marxist allegiance to what she has called ''an oversimplified conception of the relationship between reality and representation.'' But I found ground for common cause in an essay in which Slack and Laurie Whitt


At the Philipps-University Marburg 14 patients with obstructive sleep apnoea syndrome (OSAS) have so far been successfully treated by surgical maxillo-mandibular advancement. These results clearly indicate that surgical treatment and cure of OSAS by maxillo-mandibular osteotomy is possible in case of an appropriate indication.


After a brief history of plasma arc cutting (PAC) is given, its types and abilities are discussed. Experimental data (unfortunately, little is available) on plasma parameters are reviewed. The status of contemporary understanding of the process involved in PAC is presented. The main emphasis is on those processes that determine the technological abilities of the method. Along with the existing theories reviewed, we propose qualitative hypotheses on some of these processes. Among them are: dependence of the cyclic cathode erosion on the rate of current increase, double arcing and the role of insulating inclusions at the nozzle orifice on double arcing, dross formation and the shape of the kerf.


In this paper, a survey of novel applications of power electronics and electric machine technology for on-site railway power supply system during the last decade in Japan to realize environmentally friendly transportation is conducted. The applications for high speed railway transportation called Shinkansen are described in Chapter 2 and for conventional railway are in Chapter 3. Not only the technologies which have been put into practical use but also the technologies which are just proposed and tested are introduced. The railway transportation in Japan has already realized CO2 emission index about 19g-CO2/person-km while the index of car is about 168g-CO2/person-km. Electrification is, as a matter of course, key technology to realize such a eco-friendly transportation and its system progresses day by day applying power electronics and electrical machine technologies. The continuing effort of railway companies and manufacturers in Japan to make the system more reliable and more ecological will be grasped in this paper.


Cu 0.62 Zn 0.38 foil was subjected to surface mechanical attrition treatment (SMAT) processing first. Growth behavior of ZnO nanostructure on the SMAT Cu 0.62 Zn 0.38 surface during thermal oxidation was investigated in this paper. The original and SMAT Cu 0.62 Zn 0.38 foils were thermally oxidized at 400 ~ 700 °C under various gaseous environments, including nitrogen and mixture of N 2 -O 2 at a pressure of 1 atm. for 3 h. The oxidized specimens were characterized with a scanning electron microscope, an X-ray diffractometer and a transmission electron microscope. It is found that nanosheets are easily formed on the SMAT specimen surface. The favorable formation of nanosheets relates to twin lamellae structure of Cu 0.62 Zn 0.38 formed during SMAT processing.


This paper investigates the relation between investment and accruals to disentangle earning-fixation hypothesis. We decompose total accruals into working capital accruals, long-term investment and non-transaction accruals to test whether the investment can explain the accruals anomalies and behavior in operating and investment cycle. We use the financial information of 135 firms listed on the Tehran Stock Exchange (TSE) from 2005 to 2011 through OLS approach and find that long-term investment and non-transaction accruals are able to predict subsequent net income and free cash flow. Whereas, working capital accruals do not have this ability. To predict subsequent ROA, the persistence of total accruals, Long-term investment and external financing decrease in longer operating cycle. Total accruals are more persistent and non-transaction accruals and external financing are less persistent in the longer investment cycle. Total accruals and external financing are inversely related to subsequent returns, implying that accruals anomalies as well as external financing anomalies exist in our sample. To predict future returns, the persistence of total accruals and working capital accruals decrease, however, the persistence of external financing and non-transaction accruals and long-term investment increase in longer operating cycle. Total accruals and non-transaction accruals are more persistent and working capital accruals and long-term investment are less persistent in longer investment cycle, but the persistence of external financing is not related to investment cycle.


We design a novel electronic commerce platform with network security using Java 2 Enterprise Edition, J2EE, and cloud computing. Most, if not all, electronic commerce enterprises and individuals are exploiting the availability of the tools and facilities to deliver electronic commerce platforms. These embed a security management model which can deal with mass security events and the large data volumes provided within cloud computing. The experimental results show that this model not only has overcome low efficiency but also has gained great improvement in data processing, to provide guaranteed security and reliability.


Abstract The PerformanceStat approach to performance management emphasizes leadership involvement, top-down accountability routines, and rapid application of data, a configuration likely to improve measured outcomes in targeted areas but with high risk of adverse effects in non-targeted or neglected areas, such as equity and social justice. We test these hypotheses in examining the impact of CompStat policing on crime reduction, the intended target, and on racial disparities in arrest rates, a neglected consequence. Event-history analysis and semi-parametric controls of 14 years of data for a nationwide sample of U.S. police departments in small- to medium-size cities find that CompStat is associated with some reduction in crime, with variation across crime types and the indication of distinct prior trends for adopters. At the same time, CompStat significantly increases the risk of arrests among blacks, especially juveniles, supporting concerns about the adverse unintended consequences.


Armstrong, Michael. 1999. Armstrong's Handbook of Human Resource Management Practice. London: Kogan Page. Beckhard, Richard, and Reuben T. Harris. 1987. Organizational Transitions: Managing Complex Change. 2nd ed. Reading, MA: Addison-Wesley. Buchanan, David, and Andrzej Huczynski. 1991. Organizational Behaviour: An Introductory Text. Harlow: Prentice Hall. French, Wendell L., Cecil Bell, and Robert A. Zawacki. 2004. Organization Development and Transformation: Managing Effective Change. 6th ed. New York: McGraw-Hill Irwin. Hall, Derek, and Laura Torrington. 1995. Personnel Management: HRM in Action. 3rd ed. Harlow: Prentice Hall.


The problems are considered and the perspective directions of the effective utilization of technical potential and technological maintenance of intensive grain production in the steppe regions of CIS are recommended.


Anthropology, sociology, and more recently philosophy have produced a number of accounts of food and eating based on the idea that food is essentially, and fundamentally, a cognitive and experiential activity. Mindful of the body and the mind, while aware of social and economic environments, these accounts range from the emotional experience of food, to the many and multifaceted contrasts intrinsic to the nature of food (life and death, raw and cooked, exotic and familiar), and can also incorporate the social and economic dichotomies associated with the selection and consumption of food. This paper stems from the same analytical tradition, but aims at a target that, at least in the academia, is still not sufficiently explored: the experience of fine dining. Specifically, I am interested in the attention that renowned chefs and exclusive restaurant environments are paying to the cognitive, perceptual, and social features of food and eating that are traditionally associated with more modest, familiar, and affordable eating practices. I begin with an analysis of the practical, but also emotional and experiential differences between "eating in" and "eating out." I then consider three concepts: Terroir, Home, and Kitchen and how they have been appropriated and shaped by the contemporary restaurant scene. It is largely incorrect, I conclude, to regard fine restaurants and cuisine as exclusive, exceptional, or eccentric experiences. One of the current and leading goals of high scale dining is to recall the intimate and familiar dimensions of food and its consumption. Furthermore, I maintain that in addition to recalling the experience of intimacy and familiarity, fine dining is able to "re-invent" it.


Family Firms are organisational forms where the continuity of the relationships between the owning family (families) and the firm is mutually beneficial to both the family and the firm. Succession is one of the key processes of continuity dynamics. Successions are often considered turning points, which may have profound consequences for continuity itself as well as for the family and firm's destiny. From the firm's point of view, successions can result in a fragmentation of ownership and in a differentiation of roles among family members. A well-managed succession process can contribute both to the continuity of the family-firm relationship and to the firm's performance. A poorly managed succession process can negatively impact on the owners' emotional attachment and generate tensions among managers undermining the firm's entrepreneurial performance. We propose an extension of the FITS 1 The paper is organised as follows. In section one we analyse the RBV and DC literature on family firms (FF) and we specify the FITS model. In section 2 the model is extended to include the effects of banking services. In Section 3 the results of the simulations are illustrated and discussed. Our conclusions suggest that family members should manage their private assets in order to make the succession more fluid. They also should consider private equity to re-compact the ownership structure and improve FF leadership. We also suggest that banks should integrate private banking and private equity services. model, which is based on a resource-based view (RBV) of family firms and on dynamic capabilities (DC). Through our model we simulate the effects of the succession on the firm's entrepreneurial performance. Our simulations help to understand the contribution that banking services, particularly private banking and private equity, can provide to the management of succession.


6013 Background: Since the publication of RECIST criteria (J Natl Cancer Inst. 2000), most investigators have used them, rather than WHO criteria, for evaluating response in clinical trials. Though comparisons on retrospective data evidenced differences between the two classifications, these were not prospectively investigated. The Groupe Francais d'Immunotherapie conducts one randomized trial in MRCC patients, then compares the effect of intravenous Interleukin-2 (IL2) and Interferon (IFN) with subcutaneous IL2+IFN in good prognosis patients. The response review committee has agreed to evaluate the response status of patients using both classifications. Methods: 68 patients were randomly designated for review. All documents, specially CT-scan images before treatment start and at first tumor response evaluation, were reviewed. The radiological images of 7 patients were not evaluable; 61 were finally assessed using both WHO and RECIST criteria. Results: Median age was 58 years (25–71); sex ratio was 13 fem...


Purpose Recent evidence suggests that increasing perimetric contrast all the way to 0 dB may not be clinically useful. This study examines whether raising the floor for point-wise sensitivities affects the ability of global indices to detect change. Methods Longitudinal data from eyes with progressive glaucoma were used. Point-wise sensitivities were censored at various cutoffs (12–19 dB). At each cutoff, mean deviations (MD) were recalculated using censored sensitivities, called censored mean deviation (CMD). Both MD and CMD were fitted using a linear model. MD and CMD rate of changes (signal) and the standard deviations (SD) of the residuals (noise) were obtained from the fitted models. The linear signal to noise ratio (LSNR) for MD (LSNRMD) and CMD (LSNRCMD) were compared. Additionally, at each cutoff, the ratios of LSNRCMD to LSNRMD were calculated and tested. Results CMD provided significantly (P <0.05) better LSNR than MD when using any point-wise sensitivity cutoff between 15–19 dB for progressing eyes. Moreover, the ratios of LSNRCMD to LSNRMD were significantly (P <0.05) greater than 1 at all cutoffs from 15–19 dB. Conclusion This study demonstrates that censoring is an effective tool to reduce variability at low sensitivities for progressing eyes. Translational Relevance This study suggests that 15–19 dB could be a more suitable endpoint for perimetric testing algorithms.


FIELD: technological processes. SUBSTANCE: invention relates to hydrometallurgical methods of processing solutions containing non-ferrous metals, by settling hydrates of non-ferrous metals by means of a magnesium-containing precipitator. In compliance with the method before using the magnesium-containing precipitator is to preliminary processed by carbonization. Preliminary processing consists in blowing water pulp of the magnesium-containing precipitator with carbon dioxide at pressure of 0.1-0.5 MPa at temperature not more than 20-25 °C for 10-30 minutes. After termination of blowing with carbon dioxide the pulp is filtered, and the filtrate containing magnesium bicarbonate, is directed to settling hydrates of non-ferrous metals from solutions. Optimum consumption of bicarbonate solution is selected on the basis of transferring 70-90 % of non-ferrous metals from solutions into hydrates non-ferrous metals, formed during settling. EFFECT: reduced residual content of magnesium in a sludge. 6 cl, 7 tbl, 7 ex


This paper deals with the problem of urban air pollution and to what extent it is caused by the burning of fossil fuels at factories or in cars, and to what extent it is due to the breathing processes of trees or the burning of natural fuels like wood. With the use of radiocarbon dating techniques the distinction between the pollutants can be made. The article describes the design of the gas proportional counter used to measure the extremely small samples of carbon in polluted air. (KRM)


This stimuli article provides an overview general aspect, their comparisons, correlations and considerations of various In-Vitro methods to measure the antioxidant defense system and to discuss a number of updated In-Vitro methods used for detection of antioxidant properties. This review article gives the information regarding the different methods that are used to perform the In-Vitro antioxidant activity. It emphasizes the method simplicity, time required, instrumentation which makes us to decide which method to be fallowed to perform antioxidant property based on the feasibilities afforded to determine it. It makes a glance regarding the advantage of different methods and which is most common method used in present days for effective analysis. On the other hand as there are advantage there may be some disadvantages which are also mentioned in this article. The research studies should also be carried mostly on the accurate methods for exact results which also act as a good reference for the further researches.


The procedure of estimating the RC moment-resisting frames under blast loading using a multi-mode adaptive pushover (MADP) analysis is investigated in the current study. The main advantage of the proposed procedure is the combination of the multi-mode and adaptive pushover analysis approaches, which has not been done in the past for blast loadings. To investigate the efficiency of the proposed approach, several RC moment-resisting frames (RC-MRFs) of the 4-, 8-, and 20- storey are considered in the study. For a better comparison, the conventional modal pushover analysis (MPA), nonlinear response history analysis (NRHA), and the proposed approach are considered in the simulations. To this end, various influential parameters including the lateral force, floor displacement, storey drift, storey drift ratio, etc. are considered. For all models, the first three mode shapes were considered in the analysis procedure, while for the case of 20 storey RC-MRF, the torsional effect is included as well. The results indicated that the proposed MADP procedure has adequate accuracy and efficiency to estimate the blast loading demand on RC-MRFs.


Equations have been derived to describe the release of non‐electrolytes from liposomal suspensions. The effects of simple physicochemical parameters are shown and the way in which slow interfacial kinetics may dominate release is predicted.


Smartphones provide new exciting opportunities to visually impaired users because these devices can support new assistive technologies that cannot be deployed on desktops or laptops. Some devices, like the iPhone, are rapidly gaining popularity among the visually impaired since the use of pre-installed screenreader applications renders these devices accessible. However, there are still some operations that require a longer time or higher mental workload to be completed by a visually impaired user. In this contribution we present a novel application for text entry, called TypeInBraille, that is based on the Braille code and hence is specifically designed for blind users.


The conventional disc wears out and brake pollutes the environment. In addition, localized heating occurs in the conventional disc brake. To tackle both of these problems, conventional disc brakes can be replaced with magnetorheological (MR) fluids brakes. MR fluids are materials having shear yield stress as a function of magnetic field. On the application of magnetic field, MR particles get aligned and increase shear resistance between relatively moving surfaces. The friction between stator and rotor increases and fulfils the braking function, which means MR fluids can be used as brake friction materials. Understanding of friction behavior is the key factor of satisfactory & reliable working of the brake system. To characterize the friction behavior of MR brake, there is a need to understand the friction behavior of conventional disc brake system. In this research work, experiments have been done to characterize the frictional characteristics of Volvo disk brake system using full-scale brake inertia dynamometer.


The present paper describes the development of a novel proton exchange membrane comprising a poly (styrene sulfonic acid-co-4-vinylpyridine) copolymer that was crosslinked with a haloalkyl crosslinker through the formation of ionic bonding linkages. The nucleophilic substitution of these crosslinked membranes as well as a model reaction between pyridine and 1-bromobutane was confirmed by nuclear


It has previously been suggested that a local pH increase at pore surfaces is responsible for desorption of polar oil components and wettability alteration in sandstone reservoirs, leading to increased oil recovery during Smart Water or Low salinity injection. The pH increase can be a result of cation exchanges at clay surfaces or at other mineral surfaces present in sandstone reservoirs, such as feldspars, which is the topic of this paper. In this study, static batch tests and dynamic sandpack flooding tests have been performed to investigate the pH development in the brine phase in contact with three common feldspars, Ab-feldspar (albite), An-feldspar (anorthite) and Or-feldspar (microcline). Temperature was varied between 23 and 130°C, and brine salinity varied from 0 ppm (de-ionized water) to 100 000 ppm NaCl in batch tests. The sandpacks were composed of 10 wt% feldspar and 90 wt% quartz, and flooded with 100 000 ppm and 1000 ppm brines. In all tests, equilibrated brine pH was monitored to study cati...


Breast cancer is a common malignancy in females in the U.S. with a 1 in 8 lifetime risk. Long-term survivors are at risk of developing metastatic disease most commonly involving the bones, lungs, central nervous system, and the liver. Metastatic breast cancer to the colon is quite rare and typically presents as widely metastatic disease. This case involves metastatic breast cancer presenting as colonic obstruction 19 years after the original diagnosis. The patient is a seventy-two year old female with a compliant of three episodes of abdominal pain occurring during the previous three months. The location of the pain was in the upper abdomen, and the pain was associated with non-bloody diarrhea. The patient denied nausea or vomiting, and each episode would last approximately 8 hours. The patient underwent a complete hysterectomy for benign indication in the remote past. The patient had a right modified radical mastectomy 19 years previously for a lobular breast cancer confined to the breast. No adjuvant therapy was administered. Colonoscopy was performed to evaluate her complaints and revealed a concentric, nodular appearing, obstructing lesion at the hepatic flexure. Subsequently, the patient underwent a right hemicolectomy to remove the strictured colonic segment at the hepatic flexure. The small and large bowel mesentery appeared thickened. Pathological examination revealed cord like cells extending from the mesentery to the submucosa. The mucosa was histologically uninvolved. Histochemical evaluation including estrogen receptor status was consistent with a breast cancer primary lesion. Metastatic work-up including physical exam, chest x-ray, bone scan, and CT scan of the abdomen revealed no evidence of metastatic disease. Concluding, this case involved metastatic disease from a remote (19 years earlier) breast cancer primary now presenting as an obstructing colonic lesion. Similar to other reported colonic breast cancer metastases, this involved a lobular breast cancer. In contrast to previous reports, no other evidence of extraintestinal metastatic disease was found. Metastatic breast cancer should be considered in any patient with previous history of primary lobular carcinoma of the breast presenting as colonic obstruction irregardless of the time interval between the original cancer diagnosis and patient presentation.


The cancer chemopreventive and cytotoxic properties of 50 extracts derived from Twilight Zone (50–150 m) sponges, gorgonians and associated bacteria, together with 15 extracts from shallow water hard corals, as well as 16 fractions derived from the methanol solubles of the Twilight Zone sponge Suberea sp, were assessed in a series of bioassays. These assays included: Induction of quinone reductase (QR), inhibition of TNF-α activated nuclear factor kappa B (NFκB), inhibition of aromatase, interaction with retinoid X receptor (RXR), inhibition of nitric oxide (NO) synthase, inhibition 2,2-diphenyl-1-picrylhydrazyl radical scavenging (DPPH), and inhibition of HL-60 and MCF-7 cell proliferation. The results of these assays showed that at least 10 extracts and five fractions inhibited NFκB by greater than 60%, two extracts and two fractions inhibited DPPH by more than 50%, nine extracts and two fractions affected the survival of HL-60 cells, no extracts or fractions affected RXR, three extracts and six fractions affected quinone reductase (QR), three extracts and 12 fractions significantly inhibited aromatase, four extracts and five fractions inhibited nitric oxide synthase, and one extract and no fractions inhibited the growth of MCF-7 cells by more than 95%. These data revealed the tested samples to have many and varied activities, making them, as shown with the extract of the Suberea species, useful starting points for further fractionation and purification. Moreover, the large number of samples demonstrating activity in only one or sometimes two assays accentuates the potential of the Twilight Zone, as a largely unexplored habitat, for the discovery of selectively bioactive compounds. The overall high hit rate in many of the employed assays is considered to be a significant finding in terms of "normal" hit rates associated with similar samples from shallower depths.


Clarke, Robert C. and David W. Pate. Medical Marijuana, 1994. Journal of the International Hemp Association 1: 9-12. Cannabis is a plant with worldwide distribution, yielding fiber and food, as well as a psychoactive drug. The flowers have been used as a medicine for millennia. Investigation of its major chemical components has revealed their utility for the treatment o f a wide variety of diseases. Delta-9-tetrahydrocannabinol is currently approved as an oral prescription drug for the treatment of the nausea and vomiting associated with cancer chemotherapy and for appetite stimulation in cases of the anorexia associated with AIDS. However, many patients find that smoking Cannabis offers a superior route of administration and therefore illicitly self-medicate.


(73) Assignee: Eclipse Gaming Systems, LLC, (57) ABSTRACT Lawrenceville, GA (US) In one embodiment, a method comprising receiving indica tions of a game event from one or more of a plurality of (21) Appl. No.: 14/269,285 gaming machines, the game event corresponding to an out come of an instance of game play; and automatically contrib (22) Filed: May 5, 2014 uting to a progressive pool based on the indications.


During August 1958, a program designed to investigate the diseases of monkeys was undertaken jointly by the School of Veterinary Medicine, University of Pennsylvania and Merck Sharp & Dohme. The purposes of this program were twofold: (1) to define the problems responsible for the deaths of captive monkeys in order that suitable corrective measures might be instituted; and (2) to add as much information as possible to the biological pool of knowledge. During the early part of the investigation, it was found that mortality was a complex problem and that, as other workers in the field had suspected, it revolved around a "vicious" cycle of malnutrition, stress, and infectious disease. In the discussion that follows, each aspect of the cycle will be treated separately before a correlation of the interrelationships is made.


AIM:To investigate the effect of casein phosphopeptide-amorphic calcium phosphate(CPP-ACP) on the acid production of Lactobacillus fermentum and to evaluate the possibility of CPP-ACP as a biological anti-caries agent.METHODS: Lactobacillus fermentum was inoculated in medium containing 1% sucrose and different concentrations of CPP-ACP and grew in anaerobic condition at 37℃ for 48 hours.The primary pH values and final pH values of the supernate were measured,then the △pH was compared.RESULTS: With the concentration of CPP-ACP increasing,the final pH value of supernate rose and the △pH dropped,and the acid production of Lactobacillus fermentum decreased.CONCLUSION: CPP-ACP can inhibit the acid production of Lactobacillus fermentium.