Steroid-induced osteonecrosis is a non-infectious and avascular bone-necrosis disease, which occurs in patients receiving steroids. The common site is the epiphysis of long trunk bones such as the femoral head; however, steroid-induced osteonecrosis rarely occurs in the stomatognathic system. We report a case of suspected steroid-induced osteonecrosis arising in the mandibular condyle. The patient was a 59-year-old woman, who visited a dental clinic because of right preauricular pain, swelling, and trismus. The symptoms disappeared and recurred repeatedly for 8 months. Therefore, she was referred to our hospital for further investigation. Moreover, she had undergone relatively long-term high dose steroid therapy for sudden deafness. Computed tomography revealed osteolytic changes around the right mandibular condyle. Magnetic resonance imaging revealed a lower intensity on T1-weighted images and a high intensity on T2-weighted images around the right mandible condyle area. Moreover, it showed swelling of right masseter muscle, inside and outside pterygoid muscles. Bone scintigraphy demonstrated abnormal diffuse accumulation of technetium-99m methylene diphosphonate (99m Tc-MDP) in the region of the right mandible. On the basis of the imaging findings, osteomyelitis of mandible was diagnosed. We administered antibiotics and performed the following surgical treatment with the patient under general anesthesia: right mandibular segmentectomy and reconstruction with a free peroneal osteocutaneous flap. Histopathologic examination of the resected specimen revealed osteonecrosis of the mandible. There was no source of the odontogenic infection. Therefore, possible involvement of steroid-induced osteonecrosis in the development of these symptoms was assumed. The postoperative course was uneventful.


This article is based on the analysis of semantic, syntactic and stylistic characteristics of synecdoche in Ivo Andric's novel The Bridge on the Drina , in Serbian and its translation into French. This is a lexeme-based study where parts of the body are used to represent the whole through the synecdochic process, sometimes metonymic. The aim of this article is to prove that by using a part of the body (with a precise motivation) the author refers to its whole, which leads to a wider view of reality. The obtained results from the contrastive and descriptive analysis have to demonstrate that synecdoche is an independent figure of speech, that the mechanisms of its formation are similar in these languages, but opposed to the metonymic processes, and that the change of the synecdoche form in the context of translation influences the stylistic effect of the text.


Pale, soft, exudative (PSE), normal, and dark, firm, dry (DFD) pork was held 7 days at 4°C under light or dark then color was evaluated instrumentally and visually. Change in reflectance (R630-R580) was used to estimate color changes due to oxymyoglobin. PSE pork was lighter (higher L * ) than normal and DFD pork, but did not change over time. An increase in a * and R630-R580 occurred the first day for normal and DFD, but not for PSE samples. A subsequent increase in hue angle and decrease in R630-R580 (loss of redness) occurred in PSE and normal, but not in DFD samples. Changes in hue angle and R630-R580 were more rapid in PSE than in normal samples. Light exposure accelerated all changes except L * . Visual redness inversely correlated with L * value.


We show that the Sagittarius dwarf tidal stream can be traced with very red K/M-giant stars, selected from Sloan Digital Sky Survey (SDSS) photometry. A subset of these stars are spectroscopically confirmed with SEGUE and SDSS spectra, and the distance scale of 2MASS and SDSS M giants is calibrated to the RR Lyrae distance scale. The absolute magnitude of the K/M-giant stars at the tip of the giant branch is . The line-of-sight velocities of the M giant and blue horizontal-branch (BHB) stars that are spatially coincident with the Sgr dwarf tidal stream are consistent with those of previous authors, reinforcing the need for new models that can explain all of the Sgr tidal debris stream observations. We estimate stellar densities along the tidal tails that can be used to help constrain future models. The K/M giant, BHB, and F-turnoff stars in the lower surface brightness tidal stream that is adjacent to the main leading Sgr dwarf tidal tail have velocities and metallicities that are similar to those of the stars in the leading tidal tail. The ratio of K/M giants to BHBs and BHBs to F-turnoff stars are also similar for both branches of the leading tidal tail. We show that there is an additional low-metallicity tidal stream near the Sgr trailing tidal tail.


While more innovation is the main theoretical benefit of patent protection, some have argued an increasingly swamped U.S. Patent Office has granted many patents with negligible innovation value. I test this argument and determine the characteristics of patents that lack innovation value by analyzing 980 litigated patents that were subject to anticipation or obviousness decisions during the last decade. Using a selection corrected probit model, I obtain unconditional estimates of the likelihood that patents with given characteristics would be found to lack innovation value. I estimate a surprising 27 percent of all patents would be found at least partially invalid if subject to an anticipation or obviousness decision. Types of patents that have been particularly criticized, including those covering software and business methods and those owned by licensing firms, possess significantly higher innovation-based invalidity rates.


Variability in the aerial and root environments of NASA's Breadboard Project's Biomass Production Chamber (BPC) was determined. Data from two lettuce and two potato growouts were utilized. One growout of each crop was conducted prior to separating the upper and lower chambers; the other was subsequent to separation. There were little or no differences in pH, EC, or solution temperature between the upper and lower chamber or within a chamber. Variation in the aerial environment within a chamber was two to three times greater than variation between chambers for air temperature, relative humidity, and PPF. High variability in air velocity, relative to tray position, was observed. Separating the BPC had no effect on PPF, air velocity, solution temperature, pH, or EC. Separation reduced the gradient in air temperature and relative humidity between the upper and lower chambers, but increased the variability within a chamber. Variation between upper and lower chambers was within 5 percent of environmental set-points and of little or no physiological significance. In contrast, the variability within a chamber limits the capability of the BPC to generate statistically reliable data from individual tray treatments at this time.


Abstract In recent years, a number of different methods have been developed in order to update an analytical structural dynamics model using the limited data which can be obtained from vibration tests. The majority of these methods are based on correlation between the analytical and measured modal data and, in most cases, spatial completeness of the measured co-ordinates is critical. In this paper, a new method is presented which tackles the model updating problem by using an incomplete set of measured FRF data directly. It is shown that model updating methods based on modal data are, essentially, particular cases of the present generalised method in which FRF data at resonance frequencies only are employed. The advantages of using FRF data (over modal data) to update an analytical model are demonstrated. Special attention is given to the application of the method to the case where both measured modes and co-ordinates are incomplete. The practical applicability of the method is assessed based on the GARTEUR structure which has been used in a Europe-wide correlation exercise.


This paper studies the current status of E-Commerce network security, analyzes the current scheme of digital certificates update mechanism and its problems in the network?? then proposes a self-help certificate update system based on user security terminal. The method characterized by adopting security terminal to double check and verify the users during update process can ensure accuracy and validity of the user update operation, reduce the work load of the server, avoid the existence of network congestion, improve the service quality of the CA administrative organization, Meanwhile, using encrypted connection mode for communication also ensure its security.


In our busy and frenetic world, leaders face overwhelm. Never before has there been so much change on so many fronts, demanding attention, squeezing out critical reflective time and thinking space. This is time and space to develop the personal capacities to lead with greater clarity, humanity and wisdom in order for transformation to occur, to learn how to reflect on experience, to sense what is needed and to lean into the futures' emerging potential, instead of problem solving based on habitual thinking and yesterday's logic. This chapter will give reflection and reflective learning a rebranding, propelling it from dusty classrooms to become centre stage in a leader's toolkit, and will show how to apply the findings of the authors' important new research in the workplace. The new leadership process "Reflect to Create!" with its seven human capacities for inspiring, creating and leading transformational change in today's VUCA world is introduced. The four core conditions and four key practices to embed the approach are also introduced.


The poor family scholarship program is a scholarship program by Lamongan District Education Office. This scholarship is given to underprivileged students for study costs at university. The many indicators of scholarship determination result in difficulties education office in making objective decisions. The purpose is to determine the classification of scholarship recipients using the decision tree C4.5 algorithm. This algorithm has the advantage of speed informing and reading models, high accuracy, flexibility, and processing discrete and continuous data. The contribution of this research is to classify poor family scholarship participants with the C 4.5 algorithm without pruning, pre pruning, and post pruning methods. This study uses 460 data and for each attribute, it is calculated using the gain ratio formula to produce trees and decision rules. Based on the scenario that has been done the accuracy value generated after pruning is better than without pruning. The classification process using scenario post pruning technique is used as a reference for the classification of new registrants because it has the highest accuracy of 85.55%.


Harmonic resonances in a continuous rotating shaft with distributed mass are discussed. The restoring force of the shaft has geometric stiffening nonlinearity due to the extension of the shaft centerline. The effect of a distributed lateral force, such as the gravity, is assumed. The possibility of the occurrences of harmonic resonances, the shapes of resonance curves, and internal resonance phenomena are investigated.


This letter intends to reveal the mechanism of space charge suppression in low density polyethylene (LDPE)/ZnO nanocomposites. Trap level and space charge distributions were obtained from modified isothermal discharge current method and pulsed electro-acoustic (PEA) method, respectively. The results showed that ZnO nanoparticle doping introduced large amounts of deep trapping states, significantly reduced space charge accumulation and conduction current. The results can be explained in terms of deep trapping states resulted from the interface regions and morphology structure changes by nanoparticles doping, which greatly reduced the charge mobility, raised the charge injection potential at the contact and weakened impurity ionization.


An acyl-enzyme of a modified chymotrypsin in which the nitrogen NIµ2 of histidine-57 is methylated has been prepared. The rates of deacylation of this acyl-enzyme in the presence of various amines of pKa between 3.8 and 11 have been measured at several pH values. For hydrazine, two concurrent pathways of aminolysis are observed, one whose rate is proportional to the hydroxide ion concentration and one whose rate is proportional to the fraction of the active site in the non-protonated form with a pKa close to 7. For the other amines, the rates of aminolysis have been measured above pH 8 and the occurrence of two pathways is detected in most cases. From the slope of the Bronsted plot and the absence of terms second order in amine, the rate-limiting step of the hydroxide ion catalysed pathway is described as serine anion expulsion from the anionic tetrahedral intermediate (T–). The rate-limiting step of the enzymic pathway is the serine expulsion from T– catalysed by the conjugate acid of the imidazolyl group of the active site. The efficiency of the acid catalysis of the decomposition of the anionic tetrahedral intermediate is estimated for the modified and the native enzyme. With the native enzyme, this contribution to the overall catalysis is very high. Attempts to observe large rate enhancements due to intrmolecular catalysis in the aminolysis by diamines were unsuccessful. When the active site is modified, the leaving group specificity observed with the native enzyme and amino-acid amides is lost.


In order to investigate the genetic variability of under-planted young beech in Norway spruce monocultures, 100 randomly chosen individuals on the research plots Bricka and Kladje were analysed by means of isozyme gene markers at 17 polymorphic gene loci. The single locus mean value of the Gregorius (1974) allelic distance between the sample populations was relatively high (d0 = 9.6 %). The results do not support the hypothesis of a common origin of the planting material from a single ancestral population. A proposal is made for an extension of the network of forest beech seed stands for future melioration of spruce monocultures on Pohorje.


Purpose To assess tracheobronchial angles and their changes on combined inspiratory and expiratory thoracic computed tomography (CT) scans and to determine correlations between tracheobronchial angles and several indices of chronic obstructive pulmonary disease (COPD). Materials and methods A total of 80 smokers underwent combined inspiratory and expiratory CT scans. Of these, 65 subjects also performed spirometry and 55 patients were diagnosed with COPD. On CT scans, 3-dimensinal tracheobronchial angles (trachea–right main bronchus [RMB], trachea–left main bronchus [LMB], and RMB–LMB) were automatically measured by software. Lung volumes at inspiration and expiration were also automatically calculated. Changes in tracheobronchial angles between inspiration and expiration were assessed by the Mann–Whitney test. Correlations of the angles with lung volume, airflow limitation, and CT-based emphysema index were evaluated by Spearman rank correlation. Results The trachea–LMB angle was significantly smaller and the RMB–LMB angle was significantly larger at expiration than inspiration (P<0.0001). The trachea–LMB and RMB–LMB angles were significantly correlated with lung volume, particularly at expiration. The RMB–LMB angle was significantly correlated with airflow limitation and CT emphysema index (P<0.001–0.05) at inspiration and expiration, suggesting that narrowed RMB–LMB angle indicates more severe airflow limitation and larger extent of emphysema. Conclusion Tracheobronchial angles change during respiration and are correlated with severity of COPD and emphysema.


S COTT FOUND HIS CONSCIOUS INTELLIGENCE an unreliable guide to the end of a narrative. "Now I have not the slightest idea how the story is to be wound up to a catastrophe," he journalized of Woodstock (12 February 1826). "I am just in the same case as I used to be when I lost myself in former days in some country to which I was a stranger"-a willful plight familiar to his heroes. "I only tried to make that which I was actually writing diverting and interesting, leaving the rest to fate." And two years later (24 February 1828) in retrospect: "I have generally written to the middle of one of these novels, without having the least idea how it was to [end]." Alexander Welsh quotes these excerpts in a chapter called "Authority," and this is where they belong.1 For Scott's uncertain sense of ending is a reflection of the crisis of authority through which he lived, and his narrative closures express the complexity of his response to that crisis.


From applying for competitive grants to showcasing institutional collaboration and research trends, the need for research institutions to demonstrate and increase visibility of research impact is growing. The authors discuss core competencies needed to support bibliometric research and present active and completed impact measurement and visualization (IMV) projects, providing examples from health sciences and academic collaborations. For those considering development of a similar area of expertise within their library, an overview of necessary skillsets, tools, and recommendations for team building and scalability are described. IMV has the potential to be developed in libraries and integrated across research domains. As library roles continue to shift to be more data-centric, it is ever more important for libraries to identify ways to expand information professionals' data skills so that they can be seen as indispensable partners in the data ecosystem.


Objective To explore effects of level of blood sugar on recent prognosis of acute coronary syndrome. Methods 366 cases with acute coronary syndrome were divided into 3 groups: normal group, stress hyperglycaemia group(SHG) and diabetes mellitus group(DM).Each group was stratified according to levels of fasting blood glucose(Q_1:≤6.1 mmol/L,Q_2:6.2~10.0 mmol/L,Q_3≥10.0 mmol/L).Results Of 126 cases with SHG,48 cases were complicated by AMI;17,by LVF;11,by severe arrhythmia;1,by cardiogenic sudden death.Of 88 cases with DM,46 cases were complicated by AMI;22,by LVF;16,by severe arrhythmia;7,by cardiogenic sudden death.Of 152 cases with normal glucose,12 cases complicate AMI,7 cases complicate LVF,3 cases complicate(malignant) arrhythmia,0 case complicates cardiogenic sudden death.Conclusions With rising of level of blood glucose in patients with DM or SHG,the incidence rate of ill prognosis is increased,and hyperglycemia of patients with acute coronary syndrome should be strictly controlled.


Hawkrigg and Payne provide a very helpful medically focused approach to the management of prolonged school non-attendance in adolescence.1 Their emphasis on a multiagency systemic approach and on rehabilitation is particularly welcome. I would suggest that consideration of potential child protection issues is equally important in these cases. There are at least four situations in which this may arise, all of which I have come across in my own practice:

1. The young person who is experiencing maltreatment in the home and the non-attendance is a reaction to this. …


The manuscript "Advances in altimetric snow depth estimates using bi-frequency SARAL/CryoSat-2 Ka/Ku measurements." by Garner et al. shows interesting results on satellite derived snow depth on sea ice in both the Arctic and the Antarctic. This study is timely and relevant within the context of changing Arctic and Antarctic sea ice regime and how snow depth in particular is a big challenge to retrieve from satellites.


Nile tilapia (Oreochromis niloticus) fingerlings were reared in earthen ponds at three different feeding frequencies; twice daily, twice after 1 day, and twice after 2 days for a period of 7 months. Three hundred and seventy five fish were stocked into each of the nine, 150 m 2 ponds with three replicates for each treatment. The fish were fed with a commercial diet (26% crude protein). Significantly (P 0.05). Partial enterprise budget analysis indicated that feeding O. niloticus twice after 2 days in fertilized ponds is significantly profitable (P < 0.05) than feeding twice daily and after 1 day. Thus it is possible to rear O. niloticus in fertilized earthen ponds when fish are fed twice after 2 days.


A common justification for market-based school reform is increasing the variety of schooling options over a typical bureaucratic system. However, decentralization of school governance and more flexible enrollment might not lead to more diverse options if family or charter authorizer preferences are homogeneous, if governments impose strict regulations on schools, or if the increased market share of networked charter management organizations leads them to adopt similar models. We test the effects of decentralization and choice on school differentiation using an extreme case: in the city of New Orleans, charter schools make up 95 percent of the public school market. Using cluster analysis to group New Orleans schools along similar characteristics, we find evidence that, although not all schools are unique, there is considerable product differentiation. A cross-city comparison with more traditional public school systems suggests that similar differentiation might be achieved with a small market share of charters or magnets.


We describe an approach to simulate the power transients in complex (branched, ring, or mesh) transparent fiber optical networks. Simulations are performed at two time scales: first, the signal power dynamics in Erbium-doped fiber amplifiers is modeled at (sub-) millisecond scale using statistical signal descriptions. Further, the teletraffic performance of the network, such as the bit error rate, can be investigated for selected time instances at nano-second to sub-pico-second time scale using a sampled signal model (`bit-level' simulation). For the detailed simulation on `bit-level', signal information and internal states of the network components are re-used form the first simulation step at (sub-) millisecond scale. To illustrate our approach, we discuss simulations of `higher-order' transients in a ring network.


Twelve-country negotiations towards the Trans-Pacific Partnership Agreement ('TPP') are drawing to a close. The treaty has an ambitious agenda and could radically reshape trade in the Asia-Pacific region. At the same time, the TPP obligations have the potential to significantly restrict the ability of governments to regulate in the interests of public health. This article examines the impact that the TPP could have on two areas of public health regulation — tobacco control and access to medicines. It concludes that a number of legitimate concerns arise from the known content of the TPP, that the inclusion of a general health exception would be the preferable means of safeguarding the regulatory space of governments in relation to public health, and that United States proposals for stronger intellectual property protections that could restrict affordable access to medicines should be resisted. With negotiations shrouded in secrecy, TPP parties' desires to promote international trade and investment must not overshadow the need of governments to be able to implement sensible and effective public health policy.


Countries have implemented non-clinical measures to control the transmission of COVID-19, instigating high socio-economic costs. Therefore, the impact of these policies needs to be assessed appropriately. We propose a methodology inspired by event study analysis in econometrics to quantify the effect of the initial major COVID-19 non-clinical interventions, i.e., nationwide school closure and lockdown, across 7 European countries. We focus on the first implementation of these policies as the initial response to a pandemic is critical for controlling disease spread and providing robust evidence for government action and policy decision-making at the earliest pandemic stage. Besides an average mobility reduction of 7.5% (±7.0) after school closure and 13.6% (±12.1) after lockdown, we found a higher percentage of overall mobility reduction in countries that implemented lockdown within five days of school closure. COVID-19-related fatalities were significantly lower in countries that took school closure and lockdown measures at the earliest stage of the pandemic. The close succession of school closures and lockdown policies impacts mobility, lowering COVID-19-related cases and deaths. The lockdown has nearly as double an impact as the school closure impacts on mobility. This implies that the implementation of school closure policies by itself cannot be used as a replacement for the lockdown policy. Our findings provide important insight into how government policies should be shaped and implemented in future pandemics similar to COVID-19.


T Journal of General Management is concerned with the job of the senior management team who have the problem of integrating the functions of management: finance, marketing, production, industrial relations etc., and of relating the organization to its environment, in the light of technological, social, political and economic changes. Our task with the Journal is to collect, collate and disseminate information about new thinking and new practice in this field of general management. The area of General Management is rapidly emerging as a central focus for the study of management. Among practising managers there is a new awareness of the need to re-examine traditional principles and practices relating to the work of 'top management', and this is matched by a new enthusiasm for research among academics engaged in the general management field.


In March of 2020, state governments in the United States began implementing stay-at-home orders in an attempt to curtail the spread of COVID-19. As a result, most people experienced a decrease in face-to-face interactions as they limited their participation in social gatherings, travel, and in-person work. Although these orders aimed to stop the spread of COVID-19, a potential unintended consequence of these guidelines was an increase in loneliness, which has several negative mental and physical health consequences. The goals of the present study were to investigate the extent that one's romantic relationship status and living arrangements affected self-reports of loneliness and to track how self-reports of loneliness changed over the span of 1 month following the first stay-at-home orders in the United States. Participants (N = 311) reported their loneliness at three time points in 2-week intervals. Results showed considerable overlap between living arrangements and romantic relationship status in predicting loneliness; however, it appears that living with another person has a greater protective effect against loneliness compared to relationship status. That is, whereas living with others or being in a romantic relationship both predicted lower loneliness scores, one's living arrangements accounted for variance in loneliness scores beyond what was accounted for by one's relationship status. The researcher also explored whether loneliness increased across three time points throughout data collection. Results showed that loneliness levels remained approximately the same across time. An unhypothesized interaction effect did emerge between time and age. Subsequent probing of this interact effects showed that young adults experienced the greatest level of loneliness but this loneliness decreased over the month, whereas older adults experienced less loneliness but experienced a small increase in loneliness over the during this time. Together, these results suggest that certain groups of people were more likely to experience loneliness during the COVID-19 pandemic.


Various solvents including methanol, hexane, benzene, chloroform and dichloromethane were utilized for the extraction of phenolic contents from the seeds of pegnum harmala. Total phenolic contents (TPC) were determined by using Folin-Ciocalteu reagent method against gallic acid as standard by UV-Vis spectrophotometer at 765 nm while DPPH free radical scavenging activity of the extracts was measure by using UV-Vis spectrophotometer and taking reading at 517 nm and ascorbic acid as standard. Total phenolic contents 27.7 mg GA/g, 22.2 mg GA/g, 26.4 mg GA /g, 30.7 mg GA /g and 17.3 mg GA /g were for dichloromethane, benzene, chloroform, methanol and hexane extracts respectively. Methanol extract showed high TPC content and high antioxidant activity (72%) followed by dichloromethane extract (67%), chloroform extract (63 %), benzene extract (52 %) and hexane extract (48 %) respectively for 50 μL of each sample. The antioxidant activity was concentrated dependent for all the solvents and high TPC contents showed higher antioxidant activity. * Corresponding Author: Dr Zafar Iqbal  email@example.com International Journal of Biosciences | IJB | ISSN: 2220-6655 (Print), 2222-5234 (Online) http://www.innspub.net Vol. 14, No. 3, p. 121-127, 2019


Energy demand across the world is increasing and the resources are becoming scarce. The major source of power is from the conventional sources only. Some of the conventional sources of energies like thermal energy is produced from the fossil fuel coal which are depleting and is only limited to 2030. Renewable sources of energies are Solar, Wind, Biomass, etc hold bright prospect for the future. Wind industry has made rapid strides in the recent years. Wind power penetration has increased significantly in many interconnected power systems. Wind farms in remote places can also serve as stand – alone wind energy supply system. In this paper simulation of stand – alone wind energy supply system using permanent magnet synchronous generator is done.


FIELD: medical facilities. SUBSTANCE: device can be used for stimulating human nervous system by electric current. Device allows influencing onto central and peripheral nervous system by method of remote long-term stimulation by using implanted electrodes. Electric neurostimulator has non-implanted part in form of pulse-width modulation pulse transmitter unit and implanted part in form of receiving unit. Units are made for magnetic-induction coupling between each other. Pulse transmitter has re-tunable high-frequency oscillator, telemetry channel receiver, control programmed microcontroller of transmitter, control and program keyboard, liquid crystal alphabet-digital monitor and power unit. Transmitter is connected with companion aerial for transmitting high-frequency energy and for receiving telemetry data. Receiver unit has aerial for receiving high-frequency energy and for transmitting telemetry data. It also has control programmed microcontroller of receiving unit, digital-to-analog converter, amplifier, multi-channel switch, electrodes and connectors for connecting electrodes with multi-channel switch. Multi-channel switch has its working inputs and outputs, which form contacts of receiving unit, is connected with electrodes via connectors to form stimulation channels which can be put into operation together in groups or separately or all together. Device can be used for electric stimulation of different areas of brain and for epidural stimulation of spinal cord. Diseases as Parkinsonism, infantile cerebral paralysis, torsion dystonia, and spastic reactions, some forms of epilepsy and consequences of heavy cranial-brain traumas can be treated. EFFECT: widened functional capabilities. 14 cl, 12 dwg


The article shows that primary aspect of deciding the problem of fi nding the own Russian's culture unique in modern philosophy is comprehension of general system making mental dominants of Russian culture. According to the author's opinions they are absolutism, asceticism, kindness, cathedral, humility. Russian culture is embodiment of these mental dominants. These cultural dominants form in the process of the comprehension of Christian ideas by ancient Russian culture according to its mentality.


The influence of structural, thermal and electronic properties on collective electronic excitations (plasmon modes) has been investigated for thin Ag films grown at room temperature on Cu(111). For the (9 × 9)-Ag/Cu(111) structure the excitation of the two-dimensional plasmon, observed in Ag/Si(111), is forbidden by both the high corrugation of the Ag layer and the presence of the underlying metal substrate. The increase of the sp density of states at the Fermi energy induces the appearance of a broad peak a 7–8eV, assigned to a free-electron collective excitation. For increasing Ag coverage (above 20 layers), surface plasmon is confined within Ag grains, as indicated by the analysis of its dispersion relation, which is dispersionless up to a critical wave-vector. Surface plasmon confinement is removed upon annealing at 400 K. The thermal treatment induces a flattening of the Ag adlayer with a merging of Ag islands, and moreover, a strong enhancement of surface conductivity.


Aluminophosphate molecular sieve, AlPO 4 12, was synthesized using ethylenediamine as a templating agent in the hydrothermal system. Effects of pH value of the initial reaction mixture and the amount of ethylenediamine used on crystalline phase of the products were investigated. The chemical compositions of the sample are consistent with the literature data. The synthetic AlPO 4 12 samples were characterized using XRD, SEM, IR, DTA, chemical analysis and adsorption measurement. The catalytic performance of AlPO 4 12 molecular sieve in the esterification of propionic acid with n butanol was examined. The results show that AlPO 4 12 possesses good adsorption properties for water and cyclohexane, high thermal stability, and high catalytic activity for the esterification of propionic acid with n butanol.


BACKGROUND AND AIMS
The increased E. coli in colon are related to the occurrence and development of multiple diseases. Chemokines are shown to possess potentially antimicrobial activity, including Gram positive and negative bacterial pathogens. We here investigated function(s) of chemokine CXCL9 expressed in the gut epithelial cells and mechanism(s) of CXCL9 to kill E. coli.

METHODS
We generated CXCL9  fl/flpvillin-cre T mice (pvillin-cre positive mice) and their control CXCL9  fl/flpvillin-cre wmice (pvillin-cre negative mice), and then employed dextran sulfate sodium (DSS)-mediated colitis model to determine sensitivity of the CXCL9  fl/flpvillin-cre T mice. We analyzed composition of the gut microbiota by using 16S ribosomal RNA (V3-V4 variable region) sequencing and shotgun metagenomic analyses. We generated E. coli ∆FtsX (FtsX depleted E. coli) and E. coli ∆aceE (aceE depleted E. coli) by using bacterium red recombining system to investigate the mechanism(s) of CXCL9 to kill E. coli.

RESULTS
CXCL9  fl/flpvillin-cre Tmice were more sensitive to chemically induced colitis than their control littermates CXCL9  fl/flpvillin-cre wmice. After DSS treatment, there were markedly increased gut E. coli (Escherichia-Shigella) in the colonic contents of CXCL9  fl/flpvillin-cre T mice as compared to control CXCL9  fl/flpvillin-cre w mice. The increased E. coli could promote colitis through NLRC4 and caspase 1/11-mediated IL-18, which was derived from gut epithelial cells. We finally demonstrated that CXCL9 expressed in gut epithelial cells could kill the overgrown E. coli. E. coli expressed Ftsx and PDHc subunits aceE. E.coli∆aceE but not E. coli∆FtsX were resistant to CXCL9-mediated killing.

CONCLUSIONS
Gut epithelial cells-derived CXCL9 can kill the expanded E. coli through aceE to remain gut homeostasis.


The object of research is the operational condition of the ship and its changes that occur in the process of transportation of oversized and heavy cargo under the influence of multiple accidental events. A significant problem is the negative impact of the system of factors on seaworthiness and technical condition of the ship, the integrity of the cargo. Therefore, ensuring the safety of the ship, its functional reliability as a technical object is among the priorities which are extremely relevant in the process of transportation of oversized and heavy cargo.

In the course of the research the identification of the basic conditions of the surveyed ship in the process of operation was carried out. The ship in the process of transportation is defined as an aggregate of two objects – «ship – cargo». The decomposition of the stated condition into two variants «in norm» and «having problems», with three components: «seaworthiness of the ship», «technical condition of the ship», and «cargo and lashing systems». Six main operational conditions of the ship in the process of transportation of oversized and heavy cargo were established. The model of changes in the operational condition of the ship during the transportation of oversized and heavy cargo has been developed. This model enables to establish the relationship between these conditions, which are identified and formalized in the form of a single-ordered Markov process model. The process is considered as a process with a discrete time and the presence of a rotational condition with the absence of the property of ergodicity. Experimental investigations were carried out for various initial conditions and the most probable changes in the operational condition of the ship were determined for a specified number of hourly periods.

The proposed process model enables experimental investigations for various initial conditions and identification of the most probable changes in the ship's operational condition through a specified number of hours. It allows to estimate risks and make decisions on support of ship's operational condition during transportation of oversized and heavy cargo as a theoretical basis.


Many scholars argue about which theory, comparative advantage theory or competitive advantage, should be applied to guide China in the participation in the international competition. In fact, each of these theories has its limitation. This paper analyzes the defects of the two theories in the application in our nation by way of considering the requirement of the intellectual economics and the two theories' application and development in China. Putting forward that in order to increase the competitiveness of nations, the intellectual property advantage and strategy should be cultivated in combination of the above-mentioned theories.


The 'jilo' plant is a typical horticultural crop with a high thermal and water requirement with a bitter flavor fruit and possessing economical importance in several regions of Brazil. The objective of the study was to develop and to validate models for forecasting phenometric vegetative characteristics as the crop height, dry and fresh biomass of the aerial part, number of leaves and leaf area per plant and also the ones related directly to the production as the accumulated number of fruits (NFRUTOS) and accumulated production per plant (PAP), in function of thermal index for four cultivars of 'jilo', being two commercial and two introduced by IAC. The thermal index allowed good adjustments of the linear regressions presenting high values of R2 for most of the characteristics of interest. The validation of the equations was made with data of the second productive year for cultivar Cardoso and Bernacci for the characteristics NFRUTOS and PAP presenting good agreement due to the high values of R2 and all inside the interval of confidence of 95% of probability. The presented method, after adjusted for specific cultivar, can be used as important tool to estimate beginning and duration of phenological stages as well as final yield of crop.


[Objective]To investigate the effects of comprehensive community intervention on patients with type 2 diabetes mellitus.[Methods]90 type 2 diabetes mellitus patients who had the health records in Binhe community of Pinggu district in Beijing were divided into the intervention group(45 cases) and the control group(45 cases),and two groups were given routine medication treatment.On the basis of routine medication treatment,the intervention group received comprehensive community intervention which included education of knowledge about diabetes,quantification intervention for diet and exercise,scientific life style and effective medication.[Results]The fasting blood glucose,postprandial 2 hours blood glucose and glycosylated hemoglobin of the intervention group were significantly lower than that of the control group(P0.05).The cognition on diabetes and medical compliance behavior of the intervention group was better than that of the control group(P0.01).[Conclusion]The comprehensive community intervention can effectively control the blood glucose of patients with type 2 diabetes mellitus and retard the complications.


Reclaimed water has gradually become one of the main water sources for agricultural irrigation in the Northern China. Though treated, it may still contain heavy metals, salt ions and organic pollutants, and thus pose potential soil and groundwater pollution. Here, unsaturated soil water and solute movement model Hydrus-1D was used to simulate the vertical distributions of major nutrient ions SO2-4, Cl-, and NO-3in soil profile over time, in order to understand the potential risk to the underground water. Salts in the current reclaimed water were not high enough to migrate into or pollute the underground water, but were adsorbed and accumulated in soil over time at the Xinhe irrigation district of Tongzhou county. The salt ions were mainly concentrated at the surface soil layer less than 50 cm. Our data show that reclaimed water was safe for agricultural irrigation. In order to prevent the secondary salinization of surface soils, however, high frequent flooding irrigation of reclaimed water should not be allowed, but alternate irrigation of reclaimed water and well water would be recommended.


Reign periods of the Ming and Ch'ing dynasties Introduction 1. The crisis of the confucian order and didactic responses 2. Ritualist ethics and textual purism in the K'ang-hsi reign 3. Lineage discourse: gentry, local society, and the state 4. Ancestral rites and lineage in early Ch'ing scholarship 5. Ritual a nd the classics in the early Ch'ing 6. Linguistic purism and the hermeneutics of the Han learning movement 7. Ritualist ethics and the Han learning movement 8. Ritualism and gentry culture: women and lineage Conclusion Reference matter Notes Bibliography Character list Index.


The government purchase of public services,as an institutional arrangement and a tool of reform,has become durable and has been widely implemented. The connotation and values of government purchase of public services in the new era are illustrated in the regards of administrative idea,organization structure,role of government,and supply modes. The factors of government purchase of public services are analyzed related to the government,market,social organizations,public,and external environment. Accordingly it is proposed to optimize the government mechanism to integrate resources and introduce the accountability mechanism for government purchase of public services; to promote the regulated competition in services market and optimize the market supervision; strengthen the policy support for government purchase of public services and cultivate and enhance the participating ability of social organizations; overall publicize the government purchase information and explore the public participating in supervision and evaluation; and accumulate social capital and build a services supply system with social trust,mutual benefit,perfect regulation and multiple participation.


Estimation theory has been applied to a wide range of aerospace problems. Application of this expertise outside the aerospace field has been extremely limited, however. This paper describes the use of covariance error analysis techniques in evaluating the accuracy of pollution estimates obtained from a variety of concentration measuring devices. It is shown how existing software developed for aerospace applications can be applied to the estimation of pollution through the processing of measurement types involving a range of spatial and temporal responses. The modeling of pollutant concentration by meandering Gaussian plumes is described in some detail. Time averaged measurements are associated with a model of the average plume, using some of the same state parameters and thus avoiding the problem of state memory. The covariance analysis has been implemented using existing batch estimation software. This usually involves problems in handling dynamic noise; however, the white dynamic noise has been replaced by a band-limited process which can be easily accommodated by the software.


Mineral nutrition not only affects the growth and development of plant, but also directly or indirectly influences the plant resistance through many ways. The infection and development mechanism of plant disease related to mineral nutrition are discussed in this article.


BACKGROUND AND PURPOSE
The purpose of this study was to demonstrate scintigraphic evaluation of cerebral perfusion in patients with intracranial hemangiomas.

MATERIAL AND METHOD
The examination was carried out in 12 patients aged from 12 to 67 years. In all the patients cerebral angiomas were previously diagnosed and all of them were qualified for intravascular embolization. Brain scintigraphy was performed after IV injection of 99mTcECD and included the dynamic phase with images obtained every 2 seconds for 1.5 minutes and SPECT imaging. The semiquantitative analysis of regional cerebral blood flow was based on the comparison between activity in two symmetrical regions of interest. Cerebral angiography combined with intravascular embolization followed the scintigraphic examination.

RESULTS
Based on angiograms, the size of the nidus was estimated at 1.0 to 9.0 cm. In 8 patients the dynamic study showed an increased tracer accumulation in the region of angioma. On SPECT images the nidus was visualized as focally decreased perfusion in all cases. A decreased tracer accumulation in the area adjacent to the nidus was detected in 8 patients. The ratio of activity in the region of angioma to activity in normally perfused tissue calculated using the semiquantitative analysis was 52% to 89%.

CONCLUSIONS
SPECT images and dynamic phase of cerebral perfusion scintigraphy allow perfusion changes caused by the presence of intracranial angiomas to be identified.


We have determined the π band-gaps of the main carotenoids present in poly(methyl)methacrylate/buriti blends, namely, trans-β-carotene, 13-cis-β-carotene, 9-cis-β-carotene, phytofluene, and zeaxanthin. Semiempirical, model Hamiltonian, and density functional calculations were carried out to study these structures. The geometries were fully optimized using AM1, PM3, and B3LYP/6-31G(d,p) methods. The TD-DFT and ZINDO/S methods were applied for the calculation of the electronic absorption spectra of the optimized B3LYP geometries. The calculated spectra using the polarizable continuum model for the solvent effects were compared with the available experimental. © 2008 Wiley Periodicals, Inc. Int J Quantum Chem, 2009


Do women engineers make a difference? : reflections upon technological expertise as means to overthrow the foundations of a gender inequality


Awareness of employees and their motivation is the key for an organization to be efficient and effective. Based on the performance of ABC company financial statements in 2018, 2019 and 2020. There was an increase in company revenue and no decrease in expenses. In terms of the number of human resources working, that in the three years the number has not changed. The formulation of the problem in this paper is how the concept and implementation of motivation in managerial at company ABC. In this paper, using a qualitative descriptive methodology. It is stated that work motivation is a dominant and significant factor in determining work productivity. The results showed that good performance at company ABC was the implementation of motivation which included several aspects, namely human resource management; meet personal goals and help employees stay motivated; greater employee satisfaction; improve employee efficiency; create better team harmony and employee stability.


Mulussa aquifer extended the area of Rutba-Dhabaa, Western Iraq, has been studied in order to determine the most important chemical functions and interaction between rocks and groundwater (Groundwater–rocks interaction). The results of wet and dry periods indicated that Ca2+ and SO4 2- in the groundwater are the dominant ions. Average of Hydrogen Number (pH), Total Dissolved Solids (TDS), calcium (Ca2+), magnesium (Mg2+), sodium (Na+), potassium (K+), chlorine (Cl-), sulfate (SO4 2-), bicarbonate (HCO3 -) and nitrate (NO3 -) are 7.43, 718.25 mg/l, 120.8 mg/l, 40.875 mg/l, 32.865 mg/l, 2.93 mg/l, 103.527 mg/l, 195.9 mg/l, 214.85 mg/l and 4.275 mg/l respectively in the dry period, while its averages 7.33, 664.2375 mg/l, 114.25 mg/l, 35.8 mg/l, 29.28 mg/l, 2.33 mg/l, 90.3 mg/l, 181.1 mg/l, 203.85 mg/l, and 3.6 mg/l respectively in the wet period. The groundwater is characterized by low alkalinity hard to very hard water, between moderately and excessively mineralized water, and fresh to slightly water in both periods. Rock–water interaction processes are indicating that there is a possible contribution of the seawater in Mulussa aquifer, the dominant process is limestone–dolomite weathering, where the source of calcium is rather than gypsum or silicates rocks, and contribution of calcite more than dolomite in the Mulussa aquifer.


Abstract A number of aliphatic and cycloaliphatic carbonyl compounds have been ethynylated in tetrahydrofuran at atmospheric pressure using uncomplexed potassium tert-butoxide as a catalyst.


INTRODUCTION: In this study, it is aimed to adapt the Landing Error Scoring System (LESS) to Turkish. METHODS: LESS, developed by Darin Padua et al., was translated into Turkish separately by 6 researchers. Then, the translations were converted into a single "tool" in a consensus at a meeting. Expert opinion was taken 3 times to ensure the comprehensibility of the tool. The final version of the tool was created with the feedback received. After the content validity of the Turkish version was provided, pilot jump tests were performed on 9 participants to evaluate the reliability. The pilot jump tests were analyzed by both domain expert and non-domain expert raters. Afterwards, another 45 participants performed jump tests and these tests were analyzed by two raters who are experts in the domain. RESULTS: The Turkish version provided scope validity in its third version. The tool's (v.3) I-CVI value was 0 .78 minimum and 0.97 maximum; the lowest S-CVI value was 0.80 and the highest was 1.00; SCI / Ave value was found 0.88. The reliability level of all raters' intra-rater (0.81-0.92) and inter-rater (0.94-0.96) participating in the pilot study was found excellent. After the pilot analysis, the reliability level of intra-rater (0.82-0.83) and inter-rater (0.89) was found excellent in the evaluation made by only domain experts from 45 different participants. DISCUSSION AND CONCLUSION: Turkish version of LESS is a tool that can be used by professionals interested in sports and athlete's health.


Lasing from a conjugated polymer, poly(9,9-di-(2-ethylhexyl)fluorenyl-2,7′-diyl), incorporated into a glass-clad step index optical fibre structure is reported. The fibre is fabricated by filling a glass capillary with a toluene solution containing polystyrene and the conjugated polymer. Under nanosecond transverse photopumping, the fibre 1.5 cm in length exhibits laser emission at 436 nm from a Fabry-Perot cavity formed by the Fresnel reflections at the fibre end-air interfaces.


This paper presents a signal analysis method with the purpose of detecting frequency chande and acceleration amplitude of vibrating-type accelerometer's output. The method has potential application for newly developed oscillating micro accelerometers.


Bone Marrow Mesenchymal Stem Cells (BMSCs) are ideal seed cells for cell therapy, which have been through many long-term studies of in vitro and animal disease model treatment and have been widely used in preventing and treating a variety of clinical diseases caused by aging and other damage, including bone injury and regeneration, neural degenerative and injury, myocardial injury, liver cirrhosis, diabetes, lung disease and so on. BMSCs application in the treatment of orthopaedic disease is the most common and effective. By retrospective literature review, we summarize the BMSCs transplantation application in Orthopaedic disease treatment. As an ideal cell source, BMSCs was first applied in bone tissue engineering, mainly used in the treatment of long bone defect and bone nonunion; Recently, the research trends of clinical BMSCs application turned to treat degenerative diseases and genetic disorders because of its great potential, including osteoarthrits, femoral head necrosis, disc degeneration, spinal cord injury, knee varus, osteogenesis hypoplasia, hypophosphatasia and so on. The safety and efficacy of BMSCs treatment are the key issues in clinical cell therapy. There is no side effects and complications after BMSCs treatment, prove its clinical application is safe. But due to type and degree of disease and individual differences, therapeutic methods including injection method, effective concentrations, treatment window selection, cycle and therapeatic effects have a bigger difference. There is still no uniform of recognized operation standards for the treatment of the same type of disease. So BMSCs transplantation requires effective control during whole medical process and its application in orthopedic diseases is still lack of large-scale multicenter clinical study. Therefore, this review focuses on induction, summary and analysis in the research status of BMSCs in bone disease treatment, and provide new ideas and methods for BMSCs transplantation in orthopaedic disease prevention and treatment.


Autonomous navigation airborne forward-looking synthetic aperture radar (SAR) observes the anterior inferior wide area with a short cross-track dimensional linear array as azimuth aperture. This is an application scenario that is drastically different from that of side-looking space-borne or air-borne SAR systems, which acquires azimuth synthetic aperture with along-track dimension platform movement. High precision imaging with a combination of pseudo-polar formatting and overlapped sub-aperture algorithm for autonomous navigation airborne forward-looking SAR imaging is presented. With the suggested imaging method, range dimensional imaging is operated with wide band signal compression. Then, 2D pseudo-polar formatting is operated. In the following, azimuth synthetic aperture is divided into several overlapped sub-apertures. Intra sub-aperture IFFT (Inverse Fast Fourier Transform), wave front curvature phase error compensation, and inter sub-aperture IFFT are operated sequentially to finish azimuth high precision imaging. The main advantage of the proposed algorithm is its extremely high precision and low memory cost. The effectiveness and performance of the proposed algorithm are demonstrated with outdoor GBSAR (Ground Based Synthetic Aperture Radar) experiments, which possesses the same imaging geometry as the airborne forward-looking SAR (short azimuth aperture, wide azimuth swath). The profile response of the trihedral angle reflectors, placed in the imaging scene, reconstructed with the proposed imaging algorithm and back projection algorithm are compared and analyzed.


The photo conversion efficiencies of the 1st and 2nd generat ion photovoltaic solar cells are limited by the physical phenomena involved during the photo-conversion processes. An upper limit around 30% has been predicted for a monojunction silicon solar cell. In this work, we study 3rd generation solar cells named rectenna which could direct ly convert visible and infrared light into DC current. The rectenna technology is at odds with the actual photovoltaic technologies, since it is not based on the use of semi-conducting materials. We study a rectenna architecture consist ing of plasmonic nano-antennas associated with rectifying self assembled molecular diodes. We first opt imized the geometry of plasmonic nano-antennas using an FDTD method. The optimal antennas are then realized using a nano-imprint process and associated with self assembled molecular diodes in 11- ferrocenyl-undecanethiol. Finally, The I(V) characterist ics in darkness of the rectennas has been carried out using an STM. The molecular diodes exhibit averaged rect ification ratios of 5.


ADS-B is regarded as a promising fashion on UAV SAA application. With the advantages of small size, low power consumption and low cost, ADS-B is easy to be integrated and applied on small UAVs, providing precise cooperative information for UAVs to perform sense and avoid tasks. In this paper, the program of cooperative sense and avoid system based on ADS-B is proposed and an experimental platform is set up. Moreover, the closed-loop rapid-exploring random tree (CL-RRT) algorithm is applied in this system. Both the experiment and simulation results show that by the CL-RRT algorithm UAVs can effectively avoid the intruder with real ADS-B data. The feasibility and superiority of the ADS-B for small UAVs are verified in performing the sense and avoid task.


A lack of effort from the headmaster in the empowerment of women teachers in Junior High School 25 Sarolangun, good empowerment additional positions, training, and other activities in junior high. That is the empowerment of female teachers in SMPN 25 Sarolangun still be discriminated against on the principal itself. Therefore, in the face of MEA female teachers must be empowered and equal with male teachers. In addition, the principal must cooperate with local and provincial governments in order to empower women teachers in any field to match the capacities and skills of women teachers themselves


Radar target recognition (RTR), as a key technology of intelligent radar systems, has been well investigated. Accurate RTR at low signal-to-noise ratios (SNRs) still remains an open challenge. Most existing methods are based on a single radar or the homogeneous radar network, which do not fully exploit frequency-dimensional information. In this paper, a two-stream semantic feature fusion model, termed Multi-faceted Graph Attention Network (MF-GAT), is proposed to greatly improve the accuracy in the low SNR region of the heterogeneous radar network. By fusing the features extracted from the source domain and transform domain via a graph attention network model, the MF-GAT model distills higher-level semantic features before classification in a unified framework. Extensive experiments are presented to demonstrate that the proposed model can greatly improve the RTR performance at low SNRs.


In this article, two compact dual-band substrate integrated suspended line (SISL) filtering antennas with high selectivity based on dual gap-coupled patches are proposed. By using a quasi-I-shaped feedline, etching longitudinal slots on two patches placed symmetrically, and connecting a metal strip with both patches through metallized vias, three radiation nulls (RNs) are generated in the stopband. Thus, an excellent dual-band SISL filtering antenna with broadside radiation is achieved, resulting in high selectivity and deep stopband rejection. To further integrate filtering response and dual band with different radiations, a dual-band SISL filtering antenna with broadside and bidirectional beams is realized. Two RNs are introduced near the upper passband with bidirectional beams by folded C-shaped slots and parasitic strips, and the bidirectional beam is formed by inverted currents on both patches. Moreover, by connecting a T-shaped metal strip with both patches through metallized vias, an extra RN is acquired near the lower passband with broadside beams. Therefore, both sharp roll-off and different radiation in the dual band are achieved. The operating mechanism of both designs is analyzed. Two prototypes are fabricated and tested, and good agreement between simulated and tested values is observed.


Through literature study and logical analysis,the authors summarized the research objects,aims and tasks of sports training,as well as the definition of competitive ability and competitive state.The purpose was to help perfect the sports training theory system.It could be seen that there were different ideas with regard to the above aspects,which had made the relative theoretical concepts confusing.In this paper,the authors expatiated on their unique views on relative issues.


Thank you very much for downloading convergence structures and applications to functional analysis. As you may know, people have search hundreds times for their chosen novels like this convergence structures and applications to functional analysis, but end up in infectious downloads. Rather than enjoying a good book with a cup of coffee in the afternoon, instead they juggled with some infectious virus inside their desktop computer.


This article presents certain recent methodologies and some new results for the statistical analysis of probability distributions on manifolds. An important example considered in some detail here is the 2-D shape space of k-ads, comprising all configurations of k planar landmarks (k > 2)-modulo translation, scaling and rotation.


In-reactor creep of helium-pressurized 20 percent cold-worked Type 316 stain steel tubes was investigated at 375 to 575$sup 0$C. The creep strain was found to be in excess of the thermal creep of unirradiated specimens and the strain rate increased both with temperature and neutron fluence. These results are not clearly predicted by contemporary theories of creep during neutron irradiation. (auth)


actions, but also most commonly influence thyroid stimulating hormone and, rarely, gonadotrophins and growth hormone releasing hormone [1,2]. PHP 1b typically shows no features of AHO and is characterized by renal PTH resistance but preserved PTH responsiveness in bone and other tissues resulting in lack of AHO features. Generally, PHP 1b also presents no other endocrine abnormalities, although resistance to thyroid-stimulating hormone has been rarely reported. PHP type 1c is the rarest subtype. Furthermore, It is characterized by AHO and, resistance to PTH and other hormones in face of normal Gsα activity. PHP type 2 does not present with any other hormone resisPseudohypoparathyroidism type 1b due to paternal uniparental disomy of chromosome 20q: A case report


An analysis of problems occurring during the application of civil liability in legal relationships using information and communication technologies is being conducted in this scientific research. Apart from the absence of legal norms, there are conflict-of-laws rules, contradictions in which are to be resolved. The research of the turnover using digital technologies takes a big part in the legal doctrine. It must be noted that several fundamental works have appeared that make it possible to create a harmonious and non-contradictory system of legal regulation. However, there are still some unresolved questions left; for instance, ones concerning the mechanism of legal regulation of civil liability of subjects that have entered relations using digital technologies. The analysis of the civil law doctrine, the propositions of current Russian and international legislations, and legal practice have revealed a complex of problems connected to the civil liability of subjects entering legal relations using information and communication technologies. It became possible to systemize them depending on the subject and their role in the initiation or termination of the relation. A range of methods (general, general scientific and legal) has made it possible to make conclusions about the reasons why legal regulation is imperfect and why conflicts exist (to prevent them from happening in the future), formulate a legal regime of liability of subjects of the main or supporting group, suggest alterations to the current Russian legislation, aimed at bringing the owner of the information system to account.


To meet the requirement of full production of spacecraft,the application of CAPP (Computer Aided Process Planning) techniques to spacecraft integrated assembly is put forward,which can improve the level of technological design and production efficiency.The basic frames for integrated assembly process are given.And the basic modules are setting,which the management of tenological subscription,the processing document compiling system,the production guidance system,and information interactive system are concerned.


Objective to study the diabetes and acute cerebral infarction were risk factors of the disease.Methods in the course of selecting from January 2008 to December 2009 LaiYuanXian hospital records of 99 patients with cerebral infarction patients with diabetes,according to whether the divided into the treatment group(n=45) and the control group(n=54).And this topic grouping antitheses clinical analysis.Conclusion diabetes combined with cerebral infarction is DuoZhong factors of comprehensive results are stack role.Early control and intervention can reduce risk factors,the diabetes and the incidence of acute cerebral infarction.


Isolated DNA sequence which can serve as terminator region in a chimeric gene capable of being used for the transformation of plants1) Chimeric gene for the transformation of plants.2) It comprises at least, in the direction of transcription, a promoter region, a transgene and a terminator region, characterized in that the terminator region consists of at least one terminator region from a plant histone gene permitting the expression of the protein in the regions of rapid growth.3) Production of transgenic plants.


[Objective] To obtain the highly effective phosphobacteria from the Chinese pine mycorrhizal rhizosphere soil.[Methods] 16 phosphobacteria strains(P1-P16) were selected from 4-year-old(2+2) Chinese Pine Mycorrhizal Rhizosphere by Phosphate-dissolving circle law.The strain(P15) which had strongest phosphorus-dissolving ability was selected by the kit method.Its culture conditions and nutritional characteristics were conducted in liquid culture.[Result] The highest soluble phosphorus in the culture liquid was increased to 591.82 mg/L;Its growth curve was same as the Logistic equation;The optimal culture conditions as follows: liquid volume was 35 ml/100 ml flask;Rotational speed was 210 r/min;Initial pH value was 7.5-8.0;Culture temperature was 30 ℃.Its nutritional properties as follows: the best carbolic source was the glucose;the best source of nitrogen is the(NH4)2SO4;Mg2+,Ca2+,Fe3+ had no effect on the bacterial growth;the bacterial growth was promoted by Na+,Fe2+,K+ and inhibited by Mn2+.[ Conclusion ] There were lots of phosphobacteria in Chinese pine rhizosphere soil.Through PAM of micro-organisms Mycorrhizal can improve the situation of the host plant growth.


Abstract: At mid-twentieth century North American Mennonites enjoyed a broad consensus concerning their pacifist ethics, a concensus articulated best by Guy F. Hershberger at Goshen College. But in the 1950s new voices, chief among them Hershberger's colleague J. Lawrence Burkholder, challenged that consensus. In the background to the debate which ensued was Reinhold Niebuhr's all-too-rigid dichotomy between "social responsibility" and "sectarian withdrawal." Hershberger and Burkholder reached a standoff that surely has been unfortunate for Mennonite ethical discussions since the 1950s. Scholarly literature has accepted a body of lore about the conflict, but this article attempts to apply broader evidence and more careful historical method. It also suggests some of the strengths and some questionable features in the thought of each scholar and asks whether ultimately some reconciliation, or some new consensus, might have been possible. ********** The story is one of tragedy. In the 1940s and 1950s two gifted Mennonite scholars, Guy F. Hershberger and J. Lawrence Burkholder, developed different views about the nature of Mennonite pacifism. Unfortunately they did not develop a healthy dialogue, even though both were members of the "MC" Mennonite denomination, Burkholder had studied with Hershberger as an undergraduate, and from 1949 to 1961 the two were colleagues at Goshen College (albeit with some years of interruption while Burkholder finished graduate work in theology and philosophy at Princeton Theological Seminary). They kept their relations civil, yet the disagreement brought a degree of personal alienation. Overall, the tragedy did much to pre-empt a healthy discussion of ethics. Such discussion might have provided Anabaptist-related churches with broader consensus about ethics and less fragmentation of ethical thought than has actually emerged in the last half of the twentieth century. (1) If broader consensus had developed, Mennonite ethical thought might have expanded and deepened via healthy critique and ideas gained from the larger Christian church yet have retained greater appreciation than Mennonites now have for their own ethical traditions, including the persistent Mennonite vision of the faithful church. At mid-century hardly any Mennonite could match Hershberger's leadership and prominence as both a theoretician and a practical strategist of Mennonite pacifism (or "biblical nonresistance," as Hershberger and others often preferred to call it). In 1944 at the depth of World War II Hershberger had published a substantial book titled War, Peace, and Nonresistance. In it he systematically set forth the biblical basis and the historical grounding for Mennonites' pacifism. He also applied Mennonite pacifism in fresh ways, not only to military issues but also to such matters as labor relations, race relations and the principles and structures that he hoped would help keep Mennonite community life and corporate Christian witness strong. He and his denominational publisher revised and republished War, Peace, and Nonresistance in 1953 and again in 1969. Meanwhile, along with various other writings, in 1958 he added The Way of the Cross in Human Relations--a less systematic book designed especially to stare the case for Mennonite pacifism vis-a-vis other schools of Christian ethical thought. In 1991, one knowledgeable writer judged that Hershberger's War, Peace, and Nonresistance had earlier been so definitive that it had "functioned as a foundational peace theology for all the major Mennonite bodies in North America." According to J. Richard Burkholder (no kin to Lawrence), peace-related Mennonite "denominational resolutions and position statements from the 1940s to the 1960s all reflect the Hershberger consensus with no significant deviations." (2) Richard Burkholder went on to quote historian Paul Toews to the effect that Hershberger's version of "radical two-kingdom theology enabled a whole range of social and political activity. …


The present invention relates to a paste for forming the electrode having excellent electrical and physical properties is a paste composition containing a surface-modified metal powder


Ever since we moved to the Ring Gaeltacht when I was eleven, I've been trying to reconcile two worlds: my early childhood years, with the impressions of hol idays, grandparents, and the self-deprecating tones and tensions of a repressed Irish city, and my teenage years in a different, starkly beautiful landscape with a different culture and a different language, where life was deeply felt and tinged with the poetry of the past. When we lived in Waterford, I was a quiet little girl in a frock with sandals and white socks. Back then, I stood quietly to listen when spoken to. I kept my feet together and if we had visitors I sat with my hands together in my lap. My fringe fell like a dark silky curtain down over my forehead. I was the first child. I was nervous, and often played alone with my dolls behind my mother's chair in the kitchen, or played in the garden with my two young sisters, RoseAnne and Miriam.


Abstract The retention basin is a hydraulic structure for flood mitigation by storing river flow over a design flood.In this study, numerical models were adopted to simulate the flood mitigation effects by a retention basin. The largeflood condition was applied as a boundary condition to consider an abnormal flood caused by climate change. Furthermore, the two-dimensional numerical model was adopted to regenerate the complex flow pattern due to the topography and lateral flow near the retention basin. The numerical results of the one- and two-dimensional modelwere analyzed and compared. The results showed that the two-dimensional model is more applicable to assessing flood mitigation by the retention basin with a complex topography and lateral flow patterns. Key Words : retention basin, side weir, flood mitigation, abnormal flood 본 연구는 국토교통부 물관리연구사업의 연구비지원(11기술혁신C06)과 한국건설기술연구원 주요사업 도심지 홍수 예방(Smart Flood Management) 연구 개발의 연구비 지원에 의해 수행되었습니다. * Corresponding Author : Dong Sop Rhee(KICT)Tel: +82-031-910-0396 email: firstname.lastname@example.com December 4, 2013 Revised (1st August 11, 2014, 2nd August 25, 2014) Accepted September 11, 2014


Switching voltage regulators determine the power rails impedance profile at the low frequency range. The regulator electrical model along with the rail passive network enables the prediction of the design impedance profile. The accuracy gained by using a non-linear regulator model is emphasized in the paper. The impedance profile resonances are under-estimated while using a linear average regulator model. The miss prediction is more severe as the amount of regulator filter capacitance is reduced. Accurate prediction of a marginal regulator design thus necessitates the usage of a switching regulator model.


The current variety of media available to developers of technical documentation makes possible a richness of expression that goes beyond traditional conceptions. Rich and effective documentation can result from a judicious combination of media. The introduction of new media techniques to the traditions of technical documentation creates not only new opportunities, but new problems as well.
This paper presents a case study of an ongoing project at Apple Computer that encountered numerous such opportunities and problems. We show what gave rise to them, how we dealt with them, and finally present some guidelines for documentation teams contemplating going "beyond the book."


Twisted polymer fibre actuators provide high torsional rotation from stimulated volume expansion, induced either by chemical fuelling, thermal stimulation, or electrochemical charging. One key limitation of these actuators is the irreversibility of torsional stroke that limits their feasibility when considering real-life smart applications. Moreover, scaling the torsional stroke of these actuators becomes difficult when these are integrated into practically usable systems such as smart textiles, due to the external and variable opposing torque that is applied by the adjacent non-actuating fibres. Herein, a simple composite type torsional actuator made of hydrogel coated commercial textile cotton multifilament fibre is demonstrated. This novel actuator is of high moisture responsiveness, given that hydrogels are capable of providing huge volume expansion and twisting the overall system can transform the volumetric expansion to fibre untwisting based torsional actuation. Theoretical treatment of torsional actuation is also demonstrated based on the change in torsional stiffness of dry and wet fibres as well as a few externally applied torques. The agreement between experimental measurements and theoretical estimation is found reasonable, and the investigation allows the near-appropriate estimation of torsional stroke before integrating an actuator into a smart system.


This article addresses the struggle of crafting a recognized professional scholarly identity, and reflects on the significance of puppets to interrupt this struggle, assert one's voice, and creatively occupy one's space. Our interdisciplinary contribution aims to extend conversations on the realities of academic life that are often muted or diluted such as anxiety, self-doubt, weariness and failure, with implications for creative research practices. We engage the aforementioned realities through a mix of creative and whimsical writing styles (e.g., human-puppet dialogues; poetry; reflection), leveraging insights from the Jungian psychological approach to archetypal symbol and the imagination as well as transformative arts-based approaches involving storytelling, voice, and liminal space. After exploring our own experiences carving out space as creative and reflective scholar-practitioners, we discuss two examples where puppets disrupted the status quo of particular academic settings and provided opportunities for different, more spontaneous forms of engagement with the self and with others.


The current state of application of physical-chemical methods of oil recov- ery increase (MORI) at Bashkortostan deposits is analysed. The condition of development of the deposits, which are being at the completion stage, is shown. Perspectivity of displacement of residual oil with modern sediment- gel producing MORI, forming in a layer various water-shutoff screens, is proved. Main principles and mechanisms of influence on a layer of applied baffling technologies are considered. The general recommendations on their further effective use at Bashkortostan deposits are offered.


This report discusses the recent development regarding the negotiations with Iran about its nuclear program. The report provides background information on Iranian nuclear program and debates the November 24 Joint Plan of Action Elements.


Knowledge's getting its possibility" is decided by human cognitive ability, but more immediately lies on both the object's character given beforehand by subject and proper cognitive methods. "How is knowledge possible" contains such problems: what to be know, how to know, where are the limits of verification and knowledge, etc. In the aspect of object's character, should knowledge obtain its possibility, its objects would be particulars and their whole (but in fact its targets are the common existent state and way of particulars and their whole). In general progress of cognition, hypothesis is the key link and the only bridge through which cognition leaps over the gaps in logic between particular and universal and between finite and infinite; verification of hypothesis is the ultimate decisive link: only what can be supposed and can be verified can be recognized.Hypothesis and its verification are the essential factors that make knowledge possible from method. All the above factors finally limit knowledge as the expansion of human experience, and into the field can be experienced.


Apparatus for producing polarized neutrons at a reactor is described. An attempt was made to produce neutron beams with a high degree of polarization at the reflection angles of the order of the critical angle for cobalt. The polarized beam with the intensity (95 plus or minus 4)% at the angles of about 8 minutes was obtained. (auth)


Culturally sanctioned child homicide practices and criminally motivated acts of child murder result in thousands of juvenile deaths each year. Whereas research elucidating the causes and mechanisms underlying child abuse and neglect has gained national recognition and prominence, studies specifically addressing child homicide have historically been scant. Recently, however, comprehensive empirical studies have facilitated the examination of child homicide as a successional, life course process of victimization. Although homicidal deaths occur in children of all ages, risks and dynamics are not uniform. Child homicide incidence is generally bimodal, peaking in early childhood and late adolescence, periods characterized by intense competition and social rivalry. Analogous patterns of conspecific lethality have also been noted in many nonhuman primates and other social vertebrates. Although not mitigating human responsibility, descriptive comparative analyses of the behavioral changes inherent in juvenile growth and development, childhood socialization, and social competition can provide valuable insights into the proximate and ultimate causation of child homicide.


n March 2012, those of us affiliated with Gamut were deeply saddened to learn of the passing of Carl Wiens, who had been our reviews editor since the first issue. Carl's collegiate education and teaching spanned both Canada and the United States. A native of Vancouver, his initial degrees were earned at Canadian institutions: Douglas College (AA), University of British Columbia (BMus), and McGill University (MA), where his thesis examined songs by Charles Ives. He completed his Ph.D. in music theory in 1997, at the University of Michigan, with a dissertation on Stravinsky's Agon. After graduating, he taught at the University of Cincinnati's College-Conservatory of Music (1998–99) and at the University of Massachusetts Amherst's Department of Music and Dance (1999–2003). From fall 2003 onward he was at Nazareth College's Department of Music (Rochester, NY), where he attained the rank of Associate Professor and served as Program Director of Music History and Music Theory. There he taught a wide array of courses including the basic theory sequence, form and analysis, tonal and modal counterpoint, theory pedagogy, and composition lessons. A pianist from the age of four, Carl not only taught composition but remained active as a composer. Last year he heard his works performed at The Tank, a non-profit arts presenter in Manhattan, as well as at Nazareth. Around this time, his local newspaper, the Fairport-East Rochester Post, ran a "spotlight" on him and his work.


Like many specialists in public health, Clarke focuses on "ways to change and sustain our individual behaviour."1

For dietary problems, this has meant 30 years of trying to get people all over the world—in poor countries as well as rich …


The synthesis and spectroscopic studies ofnovel 2-aryl-1,4-benzoheterazepin-5(4H)-ones with potential biological activity are discussed. A combination of NMR, IR and mass spectroscopic techniques is used to characterize the prepared compounds.


The objective of this research is to analyze the differences of financial performance before and after Initial Public Offering digital startup s which are listed in Indonesian Stock Exchange in 2017 and 2018. The sample of this research is all of digital startups which are listed in Indonesian Stock Exchange in 2017 and 2018. The sample is 5 digital startups. This research use d Paired Sample t-test and Wilcoxon Sign test as the data analysis. The finding indicate d financial performance which calculated by debt to asset ratio was significant difference on digital startups between before and after Initial Public Offering. The result of this research indicated that the financial performance of digital startups before and after Initial Public Offering had an insignificant difference. The financial performance of digital startups increased after Initial Public Offering.


Background and Objectives: Neonatal jaundice as a result of bilirubin accumulation is one of the diseases that affect infants during the first days of life. AFP (alphafeto protein) with many physiologic roles is made in liver and yolk sac of fetus; it increases during pregnancy and decreases rapidly after delivery. This study conducted about the serum bilirubin (Bi) and AFP correlation in patients with hyperbilirubinemia in neonatal period. Materials and Methods: One hundred normal and healthy neonates with icter and hyperbilirubinemia enrolled in this study, all were under 28 day's age, and had only exaggerated physiologic jaundice. Septicemia and any other pathologic conditions "except jaundice" were excluding criterias.For each cases questioner fulfilled, AFP and Bi measured at the same time. Data analyzed by SPSS-13. Results: 66 cases were male and 34 were female, the mean amount of AFP and age of patients showed no meaningful relation between them (P=0.21).There was not meaningful relationship between AFP and sex (P=0.24).AFP and the onset time of icter (P=0.1) and serum bilirubin (P =0.87) did not show significant correlation. Weight of birth and blood groups ABO and Rh (P= 0.24, P=0.06, P= 0.526 respectively) had no meaningful relationship. Conclusion: There was not significant relationship between AFP and serum bilirubin, age, sex, weight, onset of icter and blood groups of patients.


In this paper, the temperature dependence of bound exciton luminescence on GaP: N has been studied in the range of 15K—150K using band excitation. The luminescence-kinetic method was used to investigate the energy transfer process among different luminescent centers and the luminesence quenching process related to binding mechanism in the samples with different nitrogen concentrations and different nonradiative recombination conditions. The analyses reveal that nonradiative rccombination is a very important factor in the transfer and thermal quenching proccsses. Because the nonradiative recombination probability increases with increasing temperature, the apparent activation energies of the thermal quenching processes are larger than the activation energies related to the thermalization of luminescent centers, but the more evident the energy transfer is, the larger are the apparent activation energies. For NN_1 and NN_3, detailed analyses have shown that their thermal quenching mechanisms are completely consistent with the HTL model.


The purpose of this research is to study the level of development of the pharmaceutical industry, to develop recommendations to household disposal of pharmaceuticals and to propose a waste management model to climate change. The goal was achieved solution of the following objectives: analysis of the pharmaceutical industry in Kazakhstan, including within the framework of the EAEU; study of the problem of waste management and approaches to its solution; development of proposals for the management of medical waste processing. In our study we are using the following methodological algorithm of scientific research provision: analytical review of the current situation, conducting a sociological survey, building a management model in the form of a "flowchart" based on the use of a systematic approach. In the result of the provided research, it was proved that the volume of pharmaceutical drugs production is constantly growing and almost does not decrease. At the same time, the development of the pharmaceutical industry has increased the growth of waste. Therewith, the strategy of management must be focused on prevention and reduction of such effect, at finding opportunities for managing, but at the same time so as not have a negative influence on the environment. Because the environment is one of the most important aspects of human life.


Objective Discuss the perioperative nursing methods for correction of higher eyelid orbital fat flap depression.Methods Select January 2008~May 2010 with the orbital fat flap correction of upper eyelid depression in 92 patients in the perioperative give positive psychological counseling,reasonable dietary guidance,eye care,on the condition of the patient in close observation,and timely prescribed antibiotics.Results The 92 patients were followed up free eye surgery and eye nerve injury hematoma,eyelid smooth natural shape to improve significantly.That of 88(95.65%) upper eyelid fully restored.Conclusions To carry out correction of upper eyelid orbital fat flap surgery depression perioperative care of patients before surgery effective psychological intervention,good skin care,eye surgery infection prevention and control patients,postoperative patients with good psychological care,diet care,wound care while actively preventing complicantions,can increase the success rate of surgery,and that is worthy of reference.


Despite of the recent creation of self-healing materials, these materials are gaining notoriety in the last years due to their great value for society and economy. The first publications regarding this type of materials are dated on 2001. The University of Illinois was the first cutting-edge organization dedicated to self-healing materials research. Later, in 2005 and thanks to the financial support of the Dutch ministry, The Netherlands conducted for six years the Innovation Oriented research Program (IOP) on Self-Healing Materials. This fact reflects the importance of public funding for such ambitious research projects. The project TRAINER, first project dedicated to deal with self-healing materials in Spain, emerged in 2010 thanks to the support of the Spanish government and the interest of different companies and research organizations for that type of materials. The challenge of the project TRAINER is not only working on self-healing technologies of 1 and 2 generation, but also trying to adapt current technologies to provide traditional materials (concrete, polymers, ceramics, asphalts, coatings and steel) with self-healing ability. In order to achieve this goal, different approaches have been proposed: use of microorganisms, expansive agents, PVA fibres, supramolecular polymers, new corrosion inhibitors and zirconia based materials. The standardization and development of test protocols for self-healing materials is, also, another objective to be achieved through the project. This paper will present the most relevant results achieved to date. In this context, it should be highlighted the development of microcapsules reinforced with sepiolitebased nanoclays, expansive agents based on hydrogels and supramolecular polymers based on hydrazones. ICSHM2013 _________________________________________________________________________________


Sandy desertification process is a kind of windsand locomotion process.When human′s activity breaks ecosystem balance and brings about vegetational degradation,the wind acts on the earth′s surface and causes eroding,carrying and accumulating of windsand.Plant responds to sandy desertification.This paper presents two respects.One is the adapation of the structure,including the change of plant leaves,stems,roots and biomass.Another is the adapation of plant physiology,including the plant change of cellular level,such as water physiology, photosynthetic character,osmotic adjustment,hormone,protective enzye of membrane system and material metabalism, membrane lipid component.


One of the keys to effective energy management is knowing when and where energy is being used. Submetering provides a simple way of finding out as Martyn Gilbert explains.


At the present time, liver resection is the most effective treatment to achieve long-term survival in patients with intrahepatic cholangiocarcinoma.1 Most liver resection is still undertaken via the traditional "open" approach and, to a much lesser extent, the laparoscopic approach.24 Minimally invasive approach results in improved short-term outcomes such as reduced intraoperative blood loss, lower rate of wound infection/ hernia formation, shorter length of hospital stay, and earlier postoperative recovery. In the past five years, robotic technique has gained significant popularity and application in colorectal surgery, bariatric surgery, abdominal wall reconstructive surgery, gynecology, and thoracic surgery because of its advantages, mainly increased manual dexterity for the operating surgeon. Robotic technique provides an alternative method to laparoscopy to achieve cure in hepatopancreatobiliary tumors, but it is offered only by selected centers. In the current literature, description on the technical approach during robotic partial hepatectomy for carcinoma is limited. We, therefore, describe a 60-year-old woman's status after laparoscopic cholecystectomy, Roux-en-Y gastric bypass for morbid obesity, and gastrostomy tube placement (placed during her gastric bypass) who was diagnosed with a 5-cm right-sided solid liver mass on CT scan imaging requested by her primary physician for right upper quadrant abdominal pain. A CT-guided percutaneous needle biopsy confirmed the diagnosis of intrahepatic cholangiocarcinoma. After an appropriate preoperative workup and extensive discussion regarding available treatment modalities, a decision was made for minimally invasive liver resection with curative intent. The patient was taken to the operating room for a robotic partial right hepatectomy. She was placed in a supine position. Under general endotracheal anesthesia, the abdominal cavity was entered through an 8-mm cut-down intraumbilical incision. No evidence of metastatic implants was seen on diagnostic celioscopy. Five-port technique was used. Adhesions from her prior operations were taken down safely. The gastrostomy tube attachment to the anterior abdominal wall was transected using a robotic stapler to improve access for the liver resection. The operation began by division of the right coronary and triangular ligaments to fully mobilize the right lobe of the liver. Porta hepatic structures were then dissected to achieve an adequate lymphadenectomy and to isolate the right inflow vessels (hepatic artery and portal vein). A 6-inch 3-0 silk suture was used to encircle the right hepatic artery and right portal vein to facilitate later vascular clamping. Intraoperative liver ultrasound confirmed the location of the lesion. After lowering the central venous pressure to less than 5 mmHg, superficial liver parenchymal transection was started using a robotic monopolar scissor and vessel sealer. Crossing intrahepatic vascular branches were handled with a vessel sealer (<7 mm diameter) or a laparoscopic Endo Gastrointestinal Anastomosis (GIA) stapler (>7 mm diameter). Temporary ipsilateral bulldog clamps were applied on the right hepatic artery and portal vein that had been previously dissected and isolated to reduce parenchymal blood loss. The right hepatic duct pedicle was transected using the laparoscopic Endo GIA stapler, applied by a bedside surgeon. The temporary vascular clamping maneuver took place for about 20 minutes, and it is very effective in obtaining "ipsilateral Pringle" during deep liver parenchymal transection. Understanding of intrahepatic liver anatomy is key to avoid unnecessary bleeding or bile leak during deep liver parenchymal transection. Review of a highquality triple-phase CT scan is mandatory before undertaking major liver resection. The resected specimen was detached from the future liver remnant, and it was placed in a large endoscopic retrieval bag for Presented as a video at the 2nd World Congress of the International Laparoscopic Liver Society (ILLS), May 9–11, 2019, Tokyo Japan. Address correspondence and reprint requests to Iswanto Sucandy, M.D., Digestive Health Institute, AdventHealth Tampa, University of Central Florida, 3000 Medical Park Drive, Suite 500, Tampa, FL 33613. E-mail: firstname.lastname@example.com.


The Sydney Opera House - a "Grand Projet" for city and state the competition Utzon from Hellebaek to Sydney the Opera House - a project of its time stage I - the platform stage II - the roof projects for Stage III the end of the dream Utzon after Sydney.


In former experiments, one of us (Loeb, with A. J. Smith) had found that in the anterior part of Anchylostoma caninum a substance is present that has a distinctly inhibiting action upon the coagulation of the blood.1 At that time we did not carry out experiments concerning the hemolytic action of such extracts, but we noticed that in the mixtures used for the determination of the coagulationtime no distinct hemolytic influence of the extract could be observed. In the posterior part of anchylostoma little of the substance inhibiting the coagulation was present in one experiment, while in the other experiments it was absent. Boiling the extract during a period of 15 minutes caused a marked weakening of its activity, without, however, destroying it entirely. At that time Loeb had assumed that the substance present in anchylostomum would in all probability be found to be similar to hirudin, the substance of the leech which inhibits coagulation, in fact the analogy which at that time appeared to exist between the behavior of the leech and of anchylostomum induced one of us to undertake these experiments. In order to test this hypothesis we carried out new experiments. For some time past we searched for specimens of Anchylostoma caninum in all the dogs upon which we performed an autopsy. The anchylostoma found were carefully washed and afterward dried with filter-paper. The worms thus freed from adhering intestinal contents were ground up in a porcelain mortar and the ground up material was dried at a temperature varying between approximately 420 and 500 C. The dried material was scraped off and collected in a bottle for further use. In this way approximately 170 mgm. dried substance of Anchylostoma caninum were obtained, which enabled us to carry out a limited number of experiments.


The functional activity of mast cells in different types of such breast lesions as fibroadenoma and benign breast disease have been studied. The results indicate that mast cells involves in pathogenesis of breast hyperplasia.


In this work we will obtain a formula for the third regularized trace of the self adjoint differential equation of second order with nuclear class operator coefficient given in a finite interval.


Enzymatic synthesis of L-5-hydroxytryptophan from L-serine and 5-hydroxyindole catalyzed by tryptophan synthase from recombinant Escherichia coli were studied.The factors such as temperature,p H,molar ratio of L-serine to 5-hydroxyindole and substrate concentration were investigated by single-factor experiments and response surface methodology.The optimal temperature and p H value were 32 ℃ and 8.6,respectively.The optimal molar ratio of 5-hydroxyindole to L-serine was 1.1 ∶ 1.The optimal substrate concentration of L-serine was 180 mmol / L.Under the optimal conditions,the bioconversion rate of L-serine reached 86.5% after 18 h.