The present invention discloses a nano thin intumescent fire retardant coating and preparation method, belonging to the technical field of fire retardant material. Said coating component is: an aqueous emulsion of a phosphorus-containing flame retardant polyurethane, the isocyanate component, ammonium polyphosphate - montmorillonite nanocomposite flame retardant polyols charring agent, a catalyst, synergists, and coalescents Deionized water. Ammonium polyphosphate - montmorillonite nano composite flame retardant, char polyols, catalysts, and synergists ground and mixed uniformly to give a solids mixing a flame retardant aid; the aqueous phosphorus-containing flame retardant polyether ester emulsion, coalescent, deionized water, mixed, under stirring, addition of solid flame retardant aid mixing uniformly mixed, the isocyanate component was added, uniformly mixed to obtain a thin intumescent fire-resistant coating of the present invention nanometers. The fire-resistant coating, fire retardant high efficiency, good compatibility, good uniformity of dispersion of nanoclays in the fire-resistant coating.


Sensing the crowds to understand crowd dynamics can be a challenging task. Passive sensing techniques such as camera-based sensing can provide flow detection, people counting, and density estimation, but they fail to provide accurate identification of individuals mobility patterns. Active techniques such as Radio Frequency Identification (RFID) tags given to people require expensive RFID readers deployed to perform sensing. In this paper, we propose to use Bluetooth low energy (BLE) tagging as an alternative method. When low-cost BLE tags are set in advertisement mode, they can be detected by smartphones. In this paper, we design an architecture for sensing the crowds by requiring a large population carrying relatively cheap off-the-shelf BLE proximity tags, and considerably fewer participants to run scanning application on their smartphones to collect data. We performed a large experimental deployment with 600 tags and ten smartphones conducted during the five days of the world largest annual gathering (The Hajj). We were able to achieve ~90% detectability rate while effectively reconstructing the routes of the participants.


This passage is intended to show that it is essential to carry out college English teaching from the point of English stylistics.It analyses the English advertisements in the layout,syntax,vocabulary and rhetoric.It states if college Enlish teaching could be carried out from the point of stylistics that the students' cultural accomplishments could be improved,the teaching aim to foster and improve the students' ability to have a perfect command of the language could be achieved and the goal to advocate quality education to enhance the quality of the entire nation could be achieved.


Abstract An approach for the synthesis of 4-amino-2-(trifluoromethyl)quinolines via the intramolecular Friedel–Crafts reaction of 2-(1-(arylamino)-2,2,2-trifluoroethylidene)malononitrile derivatives is reported. This simple protocol provides a wide variety of 4-amino-2-(trifluoromethyl)quinolines in good to excellent yields, without any purification. Furthermore, the 2-(1-(arylamino)-2,2,2-trifluoroethylidene) malononitrile derivatives used in this project have been synthesized by the reaction of N-aryl-2,2,2-trifluoroacetimidoyl chlorides and malononitrile at ambient temperature and under microwave irradiation in excellent yields, for the first time.


Introduction: Although new treatments and diagnostic methods for Neuroendocrine Neoplasms (NEN) have been introduced, the level of access to them needs somehow to be further investigated. Objectives: to understand the aspects that influence the access to the diagnosis, follow-up and treatment of patients with NEN in Brazil. Methods: This is a cross-sectional electronic survey conducted by the Brazilian Group of Gastrointestinal Tumors (GTG) and containing sixteen questions sent to Brazilian Oncologists via messaging app, aiming to identify access profiles to diagnostic and follow-up tests among patients with NEN, in addition to proven effective treatments in the Public and Private Brazilian Health Care System. Descriptive analysis was used to report the outcomes.Results: The survey was carried out with 201 Oncologists. Since (31.8%) of the Oncologists responded that they have been trained for more than 15 years and have been working with clinical practice within the scope of the Brazilian National Health System and/or the Private Health Care. For follow-up, the most requested marker was Chromogranin A (39%). Regarding diagnosis, 35.8% of the 201 participants claim to ask for a slide review in their clinical practice, and their access to tomography and resonance (58%). When contextualizing the performance of PET Scan with Gallium 68, it is available in (15%), but a significant percentage did not have access in the Brazilian National Health System Service, corresponding to (95%). Subgroup analysis revealed statistically significant differences in the availability of Somatostatin Analogue, being offered in 56% in the Brazilian National Health System and 84% in the Private Health Care (p < 0.05). Conclusion: This is the first Brazilian research that evaluated access to diagnostic and therapeutic tools in the Brazilian scenario, showing important access limitations, especially in the public sector. In view of the results presented, these restrictions can lead to unfavorable clinical outcomes in patients with NEN in Brazil.


In this paper, a fully integrated 5GHz voltage controlled oscillator (VCO) is presented. The VCO is designed with 0.18µm silicon complementary metal oxide semiconductor (Si-CMOS) process. To achieve low phase noise, a novel varactors pair circuit is proposed to cancel effects of capacitance fluctuation that makes harmonic currents which increase phase noise of VCO. The VCO with the proposed varactor circuit has tuning range from 5.1GHz to 6.1GHz (relative value of 17.9%) and phase noise of lower than −110.8dBc/Hz at 1MHz offset over the full tuning range. Figure-of-merit-with-tuning-range (FOMT) of the proposed VCO is −182dBc/Hz.


A 66-year-old man sustained multiple injuries in a motorcycle accident, including central rupture of the right lobe of the liver. The patient was clinically stable and was observed under conservative management. Because of high fever continuing over one week after the trauma, injury of the intrahepatic bile duct was suspected. Computed tomography enhanced with Biligraphin® (DIC-CT) revealed several high density areas in the Intrahepatic hematoma, indicating injury of the intrahepatic bile duct. ERC revealed extrabiliary opacifications from B5 and B8. A drainage catheter was percutaneously placed within the subcapsular hematoma and another tube within the intrahepatic hematoma under US. Catheter injection performed later revealed communication of these cavities with the biliary tree. The patient recovered uneventfully and the catheters were removed 78 days later. The patient is well 16 months after the trauma. It is considered worthwhile to perform DIC-CT to diagnose biliary injury in patients with hepatic trauma.


In this paper, following the work of Chen, Lu and Pope, we present the general metric for Kerr-(A)dS black holes with two rotations. The corresponding Klein-Gordon equation is separated explicitly, from which we develop perturbative expansions for the angular eigenvalues in powers of the rotation parameters with D ≥ 6.


In order to explore the causes of road traffic accidents and analyze the influencing factors of the severity of the accident, this paper is based on the traffic accident record data of Dallas in 2019. Firstly, it uses Python to preprocess and render the data, and initially analyze the relationship between the independent variables and the severity of the traffic accident. Based on the preprocessed 12,392 pieces of accident data, it is divided into general accidents and major accidents according to the severity; Secondly, the adaptive K-DBSCAN density clustering algorithm is introduced to cluster the effective density according to the severity, to eliminate the noise point data, and reflect the hot spots of traffic accidents in Dallas state; Finally, the parameters of the established XGBoost classification model are traversed, and the parameters with the highest accuracy are selected, the characteristics that have an important impact on the accident severity prediction results in the feature set such as road and environment are sought. The feature importance ranking is obtained, and practical suggestions and measures are put forward from the perspective of model prediction.


Recommender system offers personalized suggestions by analyzing user preference. However, the performance falls sharply when it encounters sparse data, especially meets a cold start user. Hotel is such kind of goods that suffers a lot from sparsity issue due to extremely low rating frequency. In order to handle these issues, this paper proposes a novel hotel recommendation framework. The main contribution includes: 1) We combine collaboration filtering (CF) with content-based (CBF) method to overcome sparsity issue, while ensuring high accuracy. 2) Travel intents are introduced to provide additional information for user preference analysis. 3) To provide as broad as possible recommendations, diversity techniques are employed. 4) Several experiments are conducted on the real Ctrip1 dataset, the results show that the proposed hybrid framework is competitive against classical approaches.


The first pentagonal-bipyramidal tungsten(III) complex (Et4N)[WIII(DAPBH)(CN)2] with a N3O2-type Schiff-base ligand and two apical cyanide groups was synthesized and characterized structurally and magnetically. The complex has a low-spin (S = 1/2) ground state and features unquenched orbital angular momentum ML = ±1 causing very strong Ising-type magnetic anisotropy.


Liquidity constraints prompt the unemployed to intensify their job search, but does that produce better labour market outcomes? Using longitudinal Australian data, we test the effect of objective proxy indicators of liquidity constraints on job search and concomitant labour market outcomes. We find that liquidity constraints, specifically their severe form 'hardship', intensify job search without improving short‐run employment outcomes or objective job quality (if a job is secured), whereas subjective job quality outcomes are worse. Moreover, we find evidence that the quit intention is higher and the concomitant medium‐run employment stability is lower for those who found jobs facing hardship.


A brief discussion on the increased interest shown in bridge layout and design since 1972, with particular reference to activites in West Germany, is followed by a description of the bridges of the 8,000-dwt tankers Mandan and Dakota, which entered the service of the Hamburg owners, Atlantic-Rhederei F. & W. Joch, in 1976. This bridge design is based on the experience of these owners and their ship-masters. Each of the two ships has a spacious wheelhouse with a "bay window" type frontage which accommodates the combined command/navigation control position. At this main control-position, all control and monitoring equipment is arranged to allow the seated master or watchkeeping officer always to have a complete picture of the ship's position, traffic conditions, and functioning of the machinery, with direct control of the rudder, bow-thruster, and main engine (the machinery is arranged for 16/24-hr unmanned operation). There is also a conventional hand steering-wheel mounted between the main control-position and the large chart-table, the latter being installed in the after part of the wheelhouse together with a radio direction-finder, Decca Navigator, and other equipment. The Author (of Atlantic-Rhederei) describes these and other bridge arrangements in detail, with plan and elevation drawings showing the layout. Order from: BSRA as No. 46,784.


Mobile advertising offer great opportunities for enterprises. Understanding user adoption of mobile advertising become important in explaining mobile advertising growing at an exponential rate in these years. The purpose of this study was to analyze factors possibly affecting user adoption of mobile adervertising. This paper proposed a model for analyzing mobile advertising adoption of Chinese users. The analysis is based on a consumer survey. This paper tests the proposed model through a questionnaire survey involving 298 mobile phone users in China. The results indicate consumer attitude is mainly affected by Perceived usefulness and Perceived ease of use. It is also found that Perceived usefulness, subjective norm and consumer attitude are vital for consumer adoption. The findings provide useful suggestions and implications for academics and businesses.


IntroductionTotal hip replacement (THR) is one of the most widely used and most successful orthopedic procedures performed in developed countries. The burden of revision surgery, however, has becom...


A chronological overview of aero-optics test flights is presented highlighting the objectives and conclusions from the tests. Flight tests performed in coordination with the PRESS reentry observation missions and the ALL Cycle 2 laser propagation and tracking demonstrations are described addressing the identification and quantification of distortion phenomena. Finally, current aero-optics flight investigations of an atmospheric turbulence probe are briefly discussed.


Summary Due to the importance of tocopherols for oil stability, and consequently in almond (Prunus amygdalus Batsch) kernel quality, the concentration of the three isomers -, - and -tocopherol were determined over 2 years in oil from the kernels of a group of almond selections in five progenies obtained from crosses between eight parents. Oil content was highly variable between genotypes, ranging from 40-65% of the total kernel dry weight (DW), but was consistent over the 2 years. High variability in the concentrations of the three isomers, and of the total amount of tocopherol, were also observed, even among genotypes in the same progeny, with significant differences between progenies and individuals. In some genotypes, a significant year effect was observed, with higher concentrations in the first year, probably due to higher Summer temperatures. The concentration in -tocopherol, the isomer with the major stabilising activity, was ten-times higher than the levels of - and -tocopherol, which were similar. A significant and positive correlation was also found between the concentrations of - and -tocopherol. Tocopherol concentration was high in 'Marcona', a traditional high-quality Spanish cultivar, and in several late-blooming selections. The continuous distribution of tocopherol concentrations suggests polygenic control. Significant differences in concentrations of - and -tocopherol indicate that high tocopherol concentration is a clearly attainable objective in almond breeding.


The authors outline and justify a viable method for numerical inner-outer factorization of H/sup infinity / functions, which must be found to compute the H/sup infinity /-optimal performance for certain control problems. Inner-outer factorization of stable transfer function can be reliably computed over a finite frequency band by numerical means, under assumptions of bounded transfer function error and bounded transfer function roll-off rate. This implies that the H/sup infinity /-optimal weighted sensitivity problem is well-posed in an appropriate sense, contrary to the conclusions of other work in the literature. The theoretical justification for a numerical procedure for computing the factorization is presented, and its application is illustrated using an irrational transfer function. These results also present a partial answer to the question of the sufficiency of frequency response data for design purposes.<<ETX>>


Reactivity of diphenylsulfinyl radical cation (Ph2S.+) with model compounds of "dry/wet" ArF resists and KrF resists was investigated by pulse radiolysis technique, in order to reveal the reaction between Ph2S.+ and a polymer. Ph2S.+ is an intermediate of photolysis of triphenylsulfonium salts. Some Ph2S.+ react with other intermediate of phenyl radical, leading to the formation of (phenylthio)biphenyl products and proton (H+). The reaction, referred to as rearrangement reaction, is mainly responsible for acid generation. However, some Ph2S.+ react with a polymer. Acid-generation efficiency might be enhanced if H+ is also formed by this reaction. Among 25 model compounds employed, Ph2S.+ was scavenged by phenolic compounds which have lower electrochemical half wave reduction potential (E1/2) than that of Ph2S. However, resulting radical cations of the phenolic compounds were not observed. Ph2S.+ was not scavenged by the other compounds with higher E1/2. Decay rate constant of Ph2S.+ scavenged by additives clearly depends on the change of E1/2 between Ph2S and the additives including pyrene from which charge transfer was observed to Ph2S.+. The reaction is therefore charge transfer between the model compounds and Ph2S.+. The resulting radical cations of phenolic compounds are known to decompose to phenoxy radical and proton (H+), suggesting that the compounds contribute to the enhancement of acid-generation efficiency in a chemically amplified resist. From the viewpoint of reaction of Ph2S. + with resists, conventional polymer of KrF resist is therefore appropriate for H+ source. Phenolic compounds are generally not appropriate for the component of "dry/wet" ArF resists because of their strong absorption at 193 nm. However, the electron proved to be transferred from fluorinated methylphenols to Ph2S.+. Fluorinated methylphenols may have a potential for candidate of resist components improving acid generation in "dry/wet" ArF lithography.


A field experiment was conducted at research farm, Department of soil science and Agricultural Chemistry, Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhani University to study effect of application of varying levels of potassium and zinc on productivity, nutrient uptake and quality parameters of pigeon pea during 2017-2018.Highest seed and stover yield of pigeon pea was recorded with the combined application of 30 kg K2o + 15 kg Znso4 ha along with recommended dose of NPK fertilizers (RDF) and was at par with application of RDF + 15 kg K2o +15 kg Znso4 ha, RDF + 45 kg K2o ha + 15 kg Znso4ha was significantly superior over RDF and other treatment. Higher levels of K and Zn along with RDF also recorded higher growth and yield attributes at harvest viz., protein content, test weight, straw and seed yield of pigeon pea.


A large-scale cotemporary art exhibition entitied "Left Wing"and Planned by celebrated indepedent curator Gu Zhenqing opened on decemer 20,2003 at Left Bank Community in Zhongguancun,Beijing's answer to Silicon Valley.The exhibition eatured mew artworks by a group of the most active contemporary Chinese artists.


$17.8 billion worth of rough diamonds, or 135 million carats, are expected to be mined in 2014. This represents an increase of about three per cent over 2013 figures. About 50 mines are believed to account for 90% of global rough diamond supply in 2014, with the balance coming from private or small-scale operations, where production data is unreliable or not available at all. Below are some of the largest and most impressive.


The main purpose of this investigation is to present a preliminary study on the development of advanced methodologies to assist on the diagnosis of human articulations pathologies. In this process, a biomechanical approach is considered to characterize the patellofemoral joint. The present research work involves two distinct scientific domains, respectively, engineering and health sciences, and arises as a result of an association between the Mechanical Engineering Department of the University of Minho and a Portuguese company of medical consulting, ESPMEN. The correlation of both of these areas takes part of the highest biomedical engineer's research interests and professional ambitions. One area where this kind of approach is essential is in the understanding of patellofemoral disorders, due to their ambiguous definition, multifactorial aetiology and common thread with and impact on nearly all knee conditions. Thus, the present project represents an appealing challenge to all the involved parts. This paper describes the patellofemoral (PF) problems, from their physiopathology to epidemiology, focusing their critical question: the diagnosis, but from a conclusive perspective of resolution. Actually, since the majority of the PF cases are recurrently misdiagnosed, there is in fact an urgent need of standardization of the physical examination methods. The biomechanical approach should prospectively culminate in the development of a standard assessment methodology that could precisely diagnose the PF pathologies and moreover allow clinicians to apply the most accurate and personalized treatment to each patient.


Better staff motivation is believed enables to deliver better performances. Although it sounds essential, many companies have carried out unsuccessful program to do so. The article examines improving gamification design in Gojek app, a pioneer of ride hailing company, in Indonesia. Studies show the use of Gamification has proven to deliver many benefits and improve better performances in business. The article applies game design approach in Gojek app to improve driver's motivation as key factor to improve overall company performance. The article applies Maslow needs theory to guide the game design to improve overall drivers' motivation, loyalty, and achievements.


In this paper we propose a multiple hypotheses algorithm for joint detection and estimation of coded information in a strong phase noise channel. We also present a low complexity mixture reduction procedure which maintains very good accuracy for the belief propagation messages.


The ' May 4th Movement and the "March 1st Movement', which broke out respectively in China and South Korea in 1919, not only foreshadowed the important turning point in the transition of both nations from traditional society to modern society but also offered an opportune moment for new-style intellectuals to step onto the political arena, the representatives of whom being Chen Du-xiu, Hu Shi, Lu Xun and Liu Kuang-shun, etc. This paper attempts to expound on the "modern" change of intellectuals "social identity during the movements, such as the way of intellectuals identity change, the external and internal causes for the change, its impact on the nature, outlook and orientation of the two above-mentioned movements as well as the influence of the movements on intellectuals' ideological stand and value concepts in the 20th century, etc.


The author probes into the marriage love of the three generations of the Brangwen family in The Rainbow. The first generation Tom and Lydia's marriage is a kind of harmonious love at the superficial level of knowledge. The second generation Will and Anna's marriage is a kind of flesh love at the sacrifice of spirit. The third generation is about Ursula, her breaking away from the old relations and beginning of new explorations.


Therapeutic drug switching is commonplace across a broad range of indications and, within a drug class, is often facilitated by the availability of multiple drugs considered equivalent. Such treatment changes are often considered to improve outcomes via better efficacy or fewer side effects, or to be more cost‐effective. Drug switching can be both appropriate and beneficial for several reasons; however, switching can also be associated with negative consequences.


To define haemodynamic changes after radical retropubic prostatectomy (RP) and the predictive value of these for the outcome of erectile function (EF), as although there are predictors of the recovery of EF, penile vascular changes might also affect the recovery of EF.


【The ZnO is stabilize dielectric constant over a broad temperature range because its addition makes the relaxation time short. In this study, the composite oxide material (B $a_{0.85}$ $Ca_{0.15}$ )Ti $O_{3}$ was mixed by ZnO additive material and the dielectric polarization characteristics was studied. The relative density was over 90[%] at all specimen in the structural characteristics. Among of the specimen, the relative density of (B $a_{0.85}$ $Ca_{0.15}$ )Ti $O_{3}$ with ZnO (0.4mol) has a 95[%]. The grain size of composite oxide material with an increasing ZnO increased and it was 1.0[.mu.m]-1.22[.mu.m]. In the electrical characteristics, the charge and discharge current was increased by ZnO addition. The dielectric relaxation time was increased by space charge polarization at above 110[.deg. C] and the dielectric relaxation time was fixed by space charge polarization of para-dielectric layer at below 110[.deg. C]. The dielectric relaxation time was maximum when the grain size was small. The dielectric relaxation time is decreased with an additive material ZnO and interface polarization, existing void at the grain and grain boundary. The remnant polarization is increased and the coercive electric field is decreased by ZnO.】


Very few constraints exist on the structure and evolution of old oceanic crust due to a paucity of observations. Existing sparse seismic reflection data from old oceanic crust in the Pacific and Atlantic Oceans reveal diverse attributes of the oceanic crust and upper mantle, including variable crustal thickness, Moho reflectivity, and intracrustal features. To what extent does this heterogeneity reflect variations in processes during accretion at the mid-ocean ridge or modification by post-accretion magmatism? Here we present a series of long seismic reflection profiles around and across the Hawaiian-Emperor Seamount Chain, which can be used to address this question. Multichannel seismic reflection data were acquired around and across the Hawaiian Chain in 2018. In 2019, comparable seismic reflection data were acquired around and across the Emperor. Oceanic lithosphere in both study areas is Cretaceous in age. Seismic data from both cruises were collected with the 15-km-long streamer and 6600 cu in tuned airgun array of the R/V Marcus G. Langseth . We


ABSTRACT In the wake of the July 2016 putsch and the subsequent purge of followers of the outlawed Turkish cleric Fethullah Gülen in every sphere of Turkish life under the ruling AKP government's state of emergency, the Gülen movement (GM) is in disarray and crisis. A fruitful way to bring some analytical order to this issue is through the frame of diaspora, which we contend provides some useful analytical purchase on understanding the movement historically and in transition. The GM as it stood prior to 2016 is, we contend, best conceived as a transnational parapolitical network—a 'diaspora by design'—dedicated principally to the service, not of humanity, but of power. Based on interviews with over 70 key members of the movement conducted between 2012 and 2018, we show how, from the late 1990s Gülen and his supporters crafted a complex transnational structure that has combined extensive financial operations with a distinctive organizational morphology. We map out the contours of this structure and show how it emerged over time via instrumentalization of Gülen's parapolitical ideology and the steady accretion of politically directed, corporate projects outside Turkey. Finally, drawing again on the notion of diaspora, we offer a framework for thinking about how the movement may evolve in future as it transitions to a fragmented community in transnational in political exile.


Abstract Throughout the 20th century, life expectancy in developed countries considerably increased from 40 to 70 years. This stemmed mainly from the technological advancements in medicine that have been taking place since the end of the 19th century. Although the development of contemporary clinical medicine is undoubtedly beneficial to public health, it may also entail certain hazards. Hence, both in international and national law systems one can find legal regulations setting the limits of this development and taking into account the principles of public safety in its contemporary understanding. Both the human being as a whole and the human genome are protected de jure. The article attempts to answer the question whether the currently binding genome regulations are excessive or disproportionate. The authors use the dogmatic-legal and the theoretical-legal methods in the study. The article ends with conclusions.


A study to define firewood use and sustainability was commissioned by South Africa's Kwazulu-Natal nature conservation authorities to define current use around a small afromontane forest reserve situated in the Maputaland – Pondoland – Albany biodiversity hotspot and resource availability within that reserve in order to plan the delivery of alternatives and preserve the forest. As a step in this process, a total of 121 rural households were surveyed to define current use patterns. The results regarding firewood particulars are presented here for the first time. Rural communities used and average of 134 firewood bundles per year, representing an annual volume of 25.4 m 3 firewood. Firewood bundles lasted six days in summer and two days in winter. While 29 woody species were used, six species constituted the bulk of utilisation (70.8% of volume). Among these, Diospyros dichrophylla (5th position, 7.90% of volume used) is an abundant rapidly growing shrub occurring on degraded forest sections or fallow fields, with potential as an alternative firewood resource. The study results highlight the reliance on firewood (>90% households).


The effect of different pre-treatments to reduce the seed coat imposed dormancy in the two species of Corchorus viz. olitorius and capsularis were studied. Results Indicated that the two species exhibited significant differences In their response to various treatments. For olitorius: the best overall response was obtained when seeds were subjected to hot water treatment, the optimum durations being 6S°C for 30 minutes (80%) and 80°C for 3 minutes (79%). On the other hand, concentrated acid treatment and mechanical scarification using fine sand paper provided the most rapid and effective methods for breaking seed coat imposed dormancy (96% germination as against 13%) in capsularis seeds. Besides, the effects of sub-zero storage at −20°C for one year, and application of dry heat at 65°C for 24 hrs were also studied and the results discussed.


To improve the transconductance of operational transconductance amplifier (OTA), various architectures namely recycling folded cascode (RFC), Improved recycling folded cascode (IRFC), modified recycling folded cascode (MRFC) and high recycling folded cascode (HRFC) are existing in the literature. In this paper, further improvement in the transconductance of MRFC OTA can be achieved by shorting two nodes of its current mirror and is proposed as high modified recycling folded cascode (HMRFC) amplifier. The performance of the proposed HMRFC OTA is compared with the existing state of art OTAs. To validate the progressions in the specified parameters, recycling folded cascode (RFC), modified recycling folded cascode (MRFC) and high modified recycling folded cascode (HMRFC) OTAs are realized and implemented in UMC 180 nm process technology using Cadence Spectre for a bias current of 1.2 mA. Simulation results indicate that the proposed amplifier exhibits a DC gain of 79.47 dB, the slew rate of 194.2 V/μSec, UGB of 285.85 MHz and phase-margin of 77.12 for a load capacitance of 5 pF and also observed that the CMRR and FoMs of the proposed amplifier are better by a factor of 1.3 and 1.5 in comparison to RFC, and by a factor of 1.27 and 1.41 in comparison to MRFC OTAs respectively.


Computations giving the theoretical ionization rate and response of the AN/PDR-39(TID) radiac at 3 feet above an infinite plane uniformly contaminated with fission products from 10/sup 4/ fissions of U/sup 235/ per sq ft. are presented as a function of time after fission. The response of the USNRDL 4 pi ionization chamber and the photon pulse rate for the fission products are also presented as a function of time after fission. Disintegration-rate multipliers for each fission product nuclide per d/s of the nuclide are given; the multipliers were used to obtain the contribution of each fission product nuclide to the gross response. The theoretical ionization rate decay curve was integrated to obtain the gamma dose from the fission product mixture for various periods of time after fission. (auth)


The thesis discusses the administrative process of agriculture land consolidation. Legislation and regulations which govern this area in Slovenia are presented. It is followed by a detailed presentation of procedures for the individual stages of land consolidation in Slovenia and Austria. The study of the role and participation of the owners in the land consolidation procedure is based on questionnaire for the agricultural land owners in the land consolidation area of Ptujsko polje I, from which all further analysis are derived and presented. Data on land consolidation area and on the procedure itself were obtained from the Ministry of Agriculture, Forestry and Food of the Republic of Slovenia, Geodetski zavod Celje d.o.o. and at the Administrative unit of Ptuj. The primary purpose of the research was to explore the cooperation during the land consolidation process and satisfaction with the results of the landowners from the land consolidation area. We wanted to statistically prove its basis. In the conclusion we compared the Slovenian agricultural land consolidation process with the procedure in Austria, with the emphasis on the role of landowners in the land consolidation process.


In this paper, we empirically examine the factors that drive outsourced information systems development (ISD) project success in the post-contractual stage - that is, after the decision to outsource has been made. Specifically, we examine the impact of client expertise, vendor expertise, and project modularity on the client's and vendor's knowledge integration capabilities during the outsourcing relationship. In addition, we examine the differential impact of each firm's integrative capabilities on the success of outsourced ISD projects. We empirically examine these issues using project-level survey data from 114 U.S. firms engaging in ISD outsourcing projects.


Technologies for connected, automated or autonomous vehicles (AVs) are fast developing, so that they seem ready for substituting in the near future privately owned non-autonomous traditional vehicles (TVs) and further supporting the spread of shared vehicles both for person and good transportation. On the other hand, it may easily be anticipated that the time needed to turn the existing stock of TVs into AVs will last several years during which mixed traffic is expected. A change so great may be not technology-driven only, but also requires a carefully analysis of its several impact through well designed enhancements of tools already available to the transportation systems modelers and planners. Such enhanced tools may be casted in the general framework of multi-user class assignment to transportation networks, concerning: (i) transportation network analysis, through level-of-service models distinguishing between non-autonomous vs. autonomous vehicles, presumably sharing same infrastructure; (ii) travel demand analysis, through behavioral choice modeling paradigms, including choice between AVs vs. TVs, owned vs. shared, as well as route choice behavior; (iii) steady-state equilibrium assignment. This paper describes models and algorithms to deal with steady-state equilibrium assignment; they are used to show to which extent existing methods can still be applied as well as which issues remain still open and worth of further research efforts. © 2017 The Authors.Published by Elsevier B.V. Peer-review under responsibility ofthe scientific committee of the 20th EURO Working Group on Transportation Meeting.


Objective To explore the significance of change of BNP Level of coronary heart disease(CHD) complicated with T2 DM heart function incomplete.Methods Adopt immuuno Lucent method to check the patients plasma BNP Level of 63 cases CHD complicated with T2 DM heart function incomplete(observation group) and 62 cases CHD heart function incomplete(control gronp) and Use cardioultrasound to measure LVEF to know the function of left ventricular,then contrast analyze the two groups data.Results The BNP level of observation group is obviously higher than that of control group,while the LVEF value of the observation group is lower than that of control group(P0.05),observation group's hospitalization time is longer.Conclusion There's obvious difference among the two group's BNP level and LVEF value,so the measure of plasma BNP level can early accurately diagnose the degree of heart failure which is beneficial for timely adjusting therapy scheme,to rectify heart failure early,shorten hospitalization time and lessen mortality.


The aim of this study is to determine the factors affecting the usage of Guest Empowerment Technologies (GET) in hotels among hotel visitors in Labuan, Malaysia. The research used multiple regression for data analysis across a sample of 225 respondents who stayed in hotel at least once in a year. Their participation was voluntarily. Results confirmed that the core factor affecting users' intention to use of GET is perceived usefulness. Meanwhile, all variables are proven to be significant to each other and perceived usefulness had the strongest influencing on the users' intention to use of GET. The findings provide additional information to the hotels for further understanding their consumers' characteristics in hotels. Having this information, the proposed framework can be use as the basis for further research.


Abstract
Until the 2008 Crash, the prevailing economic orthodoxy, accepted across the broad political spectrum, was that inequality was a necessary condition for economic health. The evidence of the last four decades is that this trade-off theory – that you can have more equal or more efficient economies but not both – is incorrect. Not only do excessive concentrations of income and wealth bring social dislocation and breed public discontent with democratic institutions, but a number of studies have shown that inequality on today's scale brings slower growth and greater economic turbulence. Although there is now a broad acceptance amongst global leaders that inequality poses significant risks for social cohesion and economic stability, there has been little or no action to match the high level verbal war against inequality. As a result, inequality has carried on rising within nations since 2008. In the United Kingdom, the gap between the top and bottom has continued to widen, in part because post-2010 governments have weakened the pro-equality role of the state. Tackling inequality is now one of the most pressing issues of the day – an economic as well as a social imperative – while reversing this four decade long trend will require a major restructuring of the pro-market economic models in place across most of the rich world.


DL-Tryptophan-β-C14, but not L-phenylalanine-U-C14 nor L-tyrosine-U-C14, is incorporated into the ergoline moiety of the ergot alkaloids. The high specific activities of the bases isolated from cultures supplemented with a mixture of DL-tryptophan-β-C14and carrier L-tryptophan indicate some contribution from the D-isomer.L-Phenylalanine-U-C14 serves as a precursor of the lysergic acid and isolysergic acid derivatives which contain this amino acid in their peptide moieties. L-Tyrosine-U-C14 is not a precursor. The distribution of activity in the cultures at the end of the growth phase suggests that, in the strain of Claviceps purpurea used in these investigations, none of these aromatic amino acids is extensively degraded. All are incorporated directly into cell protein. A portion of the phenylalanine is hydroxylated to tyrosine and this pathway appears to be of major importance in tyrosine biosynthesis. All three of the amino acids were incorporated extensively into a red-brown pigment which is probably a...


This report is an attempt to understand the relationship between media and democracy in Turkey. Towards that end, it situates the media in its political and historical context. It argues that Turkey's media structure falls under the "Mediterranean or Polarised Pluralistic Model" developed by Hallin and Mancini due to the very low level of newspaper circulation, the tradition of advocacy journalism, the structure of media ownership, the absence of an autonomous profession immune to pressure from politicians, interest groups, state institutions, the army and the judiciary and the extremely low level of unionization in the media which leads to high levels of labour exploitation. The report argues that despite relative progress achieved in the EU accession process, Turkey continues to fall far below the goal of harmonizing its legal framework with the EU's acquis communitaire, mainly due to the prevalent political culture and the historical origins of state-media relations in Turkey.


From the aerial part of Bupleurum kunmingense Y. Li et S. L. Pan, three new saikosaponin derivatives named BK1, BK2 and BK3 were isolated and their structures determined as 3-0-/?glucopyranosyl-(1 ^6)-(a-rhamnopyranosyl-(l -^4))-^-glucopyranoside of 16-epz-saikogenin C, 30-/?-glucopyranosyl-( l -»6)-(a-rhamnopyranosyl-( l ->4))-/?-glucopyranoside of 30-hydroxy1 6-<?/?zsaikogenin C, and 28-O-jS-glucopyranosyl-3-O-j?-glucopyranosyl-(1 ^6)-(a-rhamnopyranosyl(1 ^4))-jS-glucopyranoside of 1 6-e/?/-saikogenin C, respectively.


Abundant but short second-generation sequencing reads make assembly difficult, leading to fragmented genomes and gene annotations. Gene structure information from RNA sequences can be used to improve the completeness and contiguity of an assembly, but bioinformatics methods have been lacking. Rascaf is a highly efficient tool leveraging long-range continuity information from intron spanning RNA sequencing (RNA-seq) read pairs to detect new contig connections. It determines a heaviest path in an exon block graph that simultaneously represents a gene and the underlying contig relationships. Rascaf is more accurate than its competitors, highly precise, and finds thousands of new verifiable connections in several draft Rosaceae genomes. Lightweight and practical, it can be readily incorporated into sequencing pipelines to improve an assembly and its gene annotations. R ecent years have seen a tremendous increase in the number and diversity of sequenced genomes (Reddy et al., 2015). More than 13,000 eukaryotes have been


Objective To detect the levels of dendritic cell (DC), analyze the changes of immune function in children with recurrent respiratory tract infection (RRI), and discuss the association and the clinical significance between them. Methods T-lymphocyte subset CD3 , CD4 , CD8 , CD4 /CD8 and indexes of IgG, IgA, IgM were detected in 53 children with RRI (RRI group), with levels of DC tested in the peripheral blood of 42 patients by flow cytometry, which were then compared with those of 36 healthy children (the control group). Results In RRI group, the levels of DC in peripheral blood were (5.21±1.74)×10 6 /L, significantly lower than those of the control group (P0.05). The levels of CD3 , CD4 , CD4 /CD8 ratio as well as IgG, IgA in RRI group were significantly lower than those of the control group (P0.01), while the levels of CD8 and IgM showed no statistical significant difference between the two groups. Conclusion There are abnormal changes in the cell immunity and body fluid immunity function. The children with RRI have lower levels of DC and decreased immune function. The contents of DC, T lymphocyte subset and immuno-globulin may be regarded as important indicators of disease severity and associated with the therapeutic effects.


Abstract Hypereosinophilic syndrome encompasses a heterogenous group of non-hematologic and hematologic disorders defined as peripheral blood eosinophilia >1500/mm3 persisting more than 6 months and eosinophilic end organ complications1,2. Löeffler endocarditis (LE) is the most common cardiac manifestation of the hypereosinophilic syndrome (HES) and represents an acute form of primary restrictive cardiomyopathy3. We report the case of a 74 years-old woman with symptoms related to congestive heart failure and weight loss. At admission the patient had tachycardia and a grade 2/6 systolic mitral murmur. Laboratory findings revealed eosinophilia, hepatocytolysis syndrome and dyslipidemia. The electrocardiogram (ECG) showed non-specific ST-segment and T wave abnormalities. The echocardiography revealed left ventricular apical thrombus and entrapment of chordae tendineae with restricted motion of mitral leaflets leading to mitral regurgitation. The diagnosis of myocarditis was confirmed by the cardiac magnetic resonance imaging which showed the presence of a left ventricular mass with low signal on steady-state free precession imaging and diffuse circumferential subendocardial late gadolinium enhancement (LGE). When discussing the etiology of the HES the following were taken into consideration: hematologic, reactive or secondary disorders. This case is distinguished by diagnosis in an elderly woman and good response to corticosteroid therapy.


We directly measured SHG and DFG phase-matching angles of the Langatate LGT until 6 µm. We found a nonlinear coefficient d11 = 0.61 pm/V, and we identified LGT as a promising crystal for an OPO pumped around 800 nm.


Regional Correlation and Depositional History using Well Log and Core Data of the GeneseoBurket from the Poseidon 8M Well, Westmoreland County PA, USA


Subject area
Human Resources Management (HRM), Industrial Relations and Strategic Management.

Study level/applicability
Post-graduate students or executive post-graduate students, Core course in Human resources Management (HRM), Industrial Relations or Strategic Management or in elective courses in Industrial Relations and Strategic HRM.

Case overview
The Personnel manager of Asian Paints Ltd., Cuddalore (Tamil Nadu) factory, found himself in a Catch 22 situation when a Union leader of the manufacturing unit refused to work. The Union leader had been transferred from the Quality Assurance department to the Production department. The case describes the sequence of events and the backdrop in which the aforementioned situation had unfolded. Given the circumstances that prevailed in the factory, the personnel manager's decision was likely to have significant impact on the factory's output.

Expected learning outcomes
The student will be able to understand the industrial relations/Union issues in a company and the role of different stakeholders, namely, management, Union, workmen and the government in a conflict scenario. The student will learn the application of principles of natural justice and will be able to evaluate the Industrial Relations (IR) strategy adopted by the organizations to prevent labor unrest at the workplace. The student will understand the impact of critical management decisions on the organization's performance in an uncertain global environment.

Supplementary materials
Teaching notes are available for educators only. Please contact your library to gain login details or email email@example.com to request teaching notes.

Subject code
CSS 6: Human Resource Management.


This paper proposes the time-delayed cubic velocity feedback control strategy to improve the isolation performance of High-Static-Low-Dynamic-Stiffness (HSLDS) vibration isolator. Firstly, the primary resonance of the controlled HSLDS vibration isolator is obtained by using multiple scales method. The equivalent damping ratio and equivalent resonance frequency are defined to study the effects of feedback gain and time delay on the primary resonance. The jump phenomenon analysis of the controlled system without and with time delay is investigated by using Sylvester resultant method and optimization method, respectively. The stability analysis of the controlled system is also considered. Then, the 1/3 subharmonic resonance of the controlled system is studied by using multiple scales method. The effects of feedback gain and time delay on the 1/3 subharmonic resonance are also presented. Finally, force transmissibility is proposed to evaluate the performance of the controlled system and compared with an equivalent linear passive vibration isolator. The results show that the vibration amplitude of the controlled system around the resonance frequency region decreases and the isolation frequency band is larger compared to the equivalent one. A better isolation performance in the high frequency band can be achieved compared to the passive HSLDS vibration isolator.


Increasing concerns about privacy breaches have caused extensive studies of privacy preserving data mining in recent years. Association rule hiding in which some of the association rules are suppressed in order to preserve privacy has been identified as a practical privacy preserving application. Most current association rule hiding techniques assume that the data to be sanitized are in one single data set. However, in the real world, data may exist in distributed environment and owned by non-trusting parties that might be willing to collaborate. In this work, we propose a framework to hide collaborative recommendation association rules where the data sets are horizontally partitioned and owned by non-trusting parties. Algorithms to hide the collaborative recommendation association rules and to merge the sanitized data sets are introduced. Performance and various side effects of the proposed approach are analyzed numerically. Comparisons with trusting-third-party approach are reported. The proposed approach shows better processing time, with similar side


The Petrashevskii Circle was troubled by intellectual fragmentation throughout its brief existence. Serious Fourierists, dissatisfied with the eclectic nature of the Petrashevskii debates, formed a new group that met regularly at Nikolai Kashkin's home, while certain writers, seeking a richer literary fare, established a circle that gathered at Sergei Durov's quarters. Both of these circles have received scholarly attention. ' But a third group has been generally neglected, even though it contained three of the most promising writers of the period, Mikhail Saltykov-Shchedrin, Vladimir Miliutin, and Valerian Maikov.2 Saltykov needs no introduction to students of Russian history. He and Petrashevskii had met while students at the Lyceum at Tsarskoe Selo, and after graduation began visiting Petrashevskii' s home where he engaged in discussions about contemporary problems.3 Eventually the young writer withdrew from those sessions along with Miliutin and Maikov, whom he had met at Petrashevskii's house. The three formed the nucleus of a new circle. Vladimir Miliutin (1826-55) was a political economist and lecturer at St. Petersburg University where he probably encountered Petrashevskii for the first time. A descendant of a famous Serbian family that had entered Muscovite service in the seventeenth century, Miliutin's ancestors had


Intramolecular charge transfers, triplet state properties, and photoisomerization of five donor/acceptor (D/A) substituted butadienes were investigated. Four of these derivatives (1−4) show dual fluorescence arising from a locally excited (LE) state and a considerably more polar intramolecular charge transfer (ICT) state. The presence of an amino substituent with the nitrogen atom directly attached to the butadiene chain is essential for observing dual fluorescence in this class of compounds. The compounds undergo E−Z photoisomerization from the excited singlet state with a quantum efficiency of about 0.1 in benzene at room temperature. The intersystem crossing efficiency for these compounds is negligible. The triplet excited-state properties of the five butadienes have been characterized via triplet−triplet sensitization with benzophenone as the donor.


This paper introduces Australian woman writer Miles Franklin (Stella Maria Sarah Miles Franklin) and explores her novel My Brilliant Career (1901) as an Australian classic. As an Australian nationalist and feminist, Franklin is best known for her endowment of the Miles Franklin Award, a major annual prize for Australian literature, and her commitment to the development of Australian literature as well. Her first novel, My Brilliant Career, was published to much acclaim and scandalous excitement. Not only does it present various portrayals of rural life but a teenage girl"s view of a life of poverty and herself as a woman in the bush. Unfortunately, the novel has remained unpublished until after the author"s death. In part, however, the international screen success of My Brilliant Career in 1979 has resulted in restoring Franklin to the forefront of Australian feminism and literature. My Brilliant Career, which intentionally blurs the line between biographical fact and fictive elements, is about a young girl named, Sybylla Melvyn, growing up in rural Australia in the 1890s. As a critic describes Franklin as being passionate, creative, prickly, critical, egotistical, self-doubting, and 'as paradoxical as a platypus,' Franklin"s girl-narrator is a fascinating and complex character with the restless ambition as well. In the end, not only does she turn down a marriage proposal from a wealth suitor; but also she declares she won"t marry at all. Instead, Sybylla wants to be a writer but is frustrated by her lack of possibilities in the bush. By following her moving from one place to another, this paper defines the novel in terms of Bildungsroman and Sybylla as an unmarried proto-ecofeminist who is ambivalent about Australian people and landscapes which she describes as being attractive and, at the same time, grim.


This article describes a combined UV-photometer and fluorimeter constructed from 3 LEDs and a few wires, all held in place with Lego bricks. The instrument has a flexible design. In its simplest version, two UV-LEDs (355 nm) are used as light source and to detect absorption, and a third LED, in the visible spectrum (e.g., 525 nm), is used to detect fluorescence. Various experiments are described: fluorescence as a function of concentration and light source intensity; quantitative measurements of quinine in tonic water, using absorption and fluorescence measurements, with results in line with those obtained on scientific instruments; a demonstration of the inner filter effect reducing fluorescence at higher concentrations; investigation of the effect of drinking tonic water on the fluorescence of quinine in urine; temperature effects on fluorescence; chloride-ion quenching of fluorescence with result comparable to those previously reported; and, finally, a demonstration of phosphorescence.


Recent research highlights the potential relevance of emotions in interface design. People can no longer be modeled as purely goal-driven, task-solving agents: They also have affective motivations ...


Context How often does colonoscopy miss adenomas? Contribution During a multicenter screening trial, experienced colonoscopists performed same-day optical (OC) and virtual colonoscopy (VC) on 1233 asymptomatic adults. Optical colonoscopy performed without knowledge of the VC findings missed 55 of 511 polyps; 21 of these polyps were adenomas measuring 6 mm or greater. Adenomas missed by OC were usually on the proximal side of a fold or near the anal verge. Virtual colonoscopy missed 14% of the adenomas that measured 6 mm or greater that were de-tected by OC. Implications Neither OC nor VC is a perfect test: Each misses 10% to 14% of adenomas that measure 6 mm or greater. The Editors Optical colonoscopy (OC) is widely accepted as the gold standard for detecting colorectal neoplasia (1, 2). However, even in the most experienced hands, this skilled examination is understandably not infallible. Retrospective analysis has suggested that the OC miss rate for adenomas 10 mm or greater is approximately 10% (3). More recently, prospective back-to-back or tandem colonoscopy studies have reported miss rates for 10-mm adenomas ranging from 0% to 6% (4, 5). However, in addition to evaluating relatively small populations of patients with a high prevalence of polyps, a notable weakness common to these studies was that they used OC as its own reference standard. In a large, prospective, multicenter trial that was primarily intended to evaluate the performance of virtual colonoscopy (VC) in asymptomatic adults (6), we also had a unique opportunity to evaluate the adenoma miss rate on OC by segmentally unblinding the results from same-day VC. By using a reference standard other than OC itself for comparison, we could uncover lesions that may be systematically missed on repeated colonoscopies. These data not only provide novel insight into OC miss rates but also indicate the relative blind spots where more attention could be focused. Methods Study Design The institutional review boards at all 3 participating medical centers approved the study protocol for same-day VC and OC, and all patients provided written informed consent. We recruited asymptomatic adults who were referred for colorectal cancer screening. Exclusion criteria were a positive stool guiaic test result or iron deficiency anemia within the past 6 months; rectal bleeding, hematochezia, or unintentional weight loss of more than 10 pounds within the past 12 months; OC within the past 10 years or barium enema within the past 5 years; personal history of adenomatous polyps, colorectal cancer, or inflammatory bowel disease; and family history of familial adenomatous polyposis or nonpolyposis cancer syndromes. Between May 2002 and June 2003, 1253 asymptomatic adults enrolled in the study. Eight patients were excluded because of failure to reach the cecum at OC, 6 patients were excluded because of inadequate colonic preparation, and another 6 patients were excluded because of computed tomography (CT) system failure. The final study group comprised 1233 asymptomatic adults (728 men and 505 women; mean age, 57.8 years) who successfully completed same-day VC and OC. Study participants underwent colonic preparation with oral intake of 90 mL of phospho-soda and 10 mg of bisacodyl. To opacify residual colonic fluid and stool for VC examination, patients also consumed dilute oral contrast as previously described (7). Our CT protocol and VC technique have also been detailed previously (6). To briefly summarize, we obtained supine and prone CT acquisitions on multidetector scanners after patient-controlled rectal insufflation of room air. One of 6 trained radiologists interpreted VC studies by using a commercially available CT colonography system (Viatronix V3D-Colon, version 1.2, Viatronix, Inc., Stony Brook, New York). We used the 3-dimensional endoluminal fly-through view primarily for detecting polyps and 2-dimensional images for confirmation and problem solving. We measured polyps on the 3-dimensional view and recorded them by segment (cecum, ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon, or rectum). We defined the proximal colon as including the cecum to the splenic flexure. We prospectively rated diagnostic confidence for each detected lesion on a 3-point scale (most certain, intermediate, and least certain). One of 17 experienced colonoscopists performed OC immediately after VC interpretation by using standard commercial video colonoscopes (Olympus, Inc., Melville, New York). The colonoscope was advanced to the cecum and then sequentially withdrawn into more distal segments for polyp detection. The colonoscopist measured polyps by using a calibrated linear probe, which is more accurate than either visual or biopsy forceps estimation (8). Our polyp-matching algorithm requires VC and OC agreement according to size (within a 50% margin of error) and location (within the same or adjacent segment). After the colonoscopist evaluated a given segment, a study nurse unblinded the VC results for the previous segment. For any suspected polyp seen on VC that measured 5 mm or greater but was not seen on the initial blinded OC, the colonoscopist closely reexamined that segment and could review the VC images for guidance. We sent all retrieved polyps for histologic examination. For all cases in which a colorectal neoplasm measuring 6 mm or greater was found on second-look OC, we retrospectively reviewed both the VC and OC images. We recorded polyp characteristics, such as size, morphologic characteristic (sessile, pedunculated, or flat), and location on VC. If the polyp was situated on a colonic fold on VC, we further subcategorized it as being located on the back (proximal) side, front (distal) side, or edge of the fold. We analyzed both supine and prone VC sets for all cases. The primary reason that diminutive polyps measuring 5 mm at VC were included for potential unblinding at OC was that, given the relative error in polyp measurement, such polyps found on second-look OC might, in fact, measure 6 mm or greater. This allows for more accurate assessment of the OC miss rate at the 6-mm threshold. We did not include unblinded polyps that measured 5 mm or less on both VC and OC examinations in the final analysis. All study participants completed a detailed questionnaire on their personal and family medical history. For the purposes of this study, particular attention was given to the question about previous abdominal or pelvic surgery, since adhesions could conceivably result in a more difficult colonoscopic examination. Statistical Analysis Prospective OC performance was compared against the enhanced reference standard of second-look OC after segmental unblinding of VC results. We estimated exact binomial 95% CIs for OC miss rates. We used the chi-square test to compare the frequency of previous abdominal surgery among patients with and without polyps missed at OC and also to compare the OC miss rates among the 3 medical centers. We calculated the 95% CIs by using Stata software, version 7.0 for Windows (Stata Corp., College Station, Texas), and performed the chi-square tests by using SAS software, version 8.0 for Windows (SAS Institute, Inc., Cary, North Carolina). Role of the Funding Source The funding source had no role in the collection, analysis, or interpretation of the data or in the decision to submit the manuscript for publication. Results The performance characteristics of VC from this prospective, multicenter screening trial, using OC as the reference standard, have been previously reported (6). Our technique of segmental unblinding also allows for a separate assessment of OC by using the blinded VC results for comparison, which is the focus of this study. We identified 1310 polyps at OC in the 1233 asymptomatic adults; 511 (39.0%) of these polyps measured 5 mm or greater (Figure 1).Of these 511 polyps, 55 (10.8%) were found only on second-look OC after segmental unblinding of VC results. Twenty-four (43.6%) of the 55 unblinded lesions were nonadenomatous, including 16 hyperplastic polyps. Of the 31 missed neoplasms, 10 adenomas that measured only 5 mm were excluded from further analysis because of their diminutive size (9). Including unblinded lesions, 554 adenomas were detected on OC in this screening sample; 210 of these measured 6 mm or greater and 51 measured 10 mm or greater. Figure 1. Polyp flowchart. In 20 patients (17 men and 3 women; mean age, 58.2 years), 21 adenomas measuring 6 mm or greater (range, 6 mm to 17 mm; mean, 8.1 mm) were found on OC only after the VC results were unblinded, which represent the lesions of primary interest for this study (Table). The corresponding adenoma miss rate on prospective OC examination was 10.0% (95% CI, 6.3% to 14.9%) (21 of 210 adenomas) at a 6-mm cutoff. The 20 patients with missed adenomas that measured 6 mm or greater represented only 1.6% of the study sample (20 of 1233 patients) but 11.9% of patients with adenomas 6 mm or greater (20 of 168 patients). At 8-mm and 10-mm thresholds, the OC adenoma miss rates by polyp were 10.5% (CI, 5.2% to 18.5%) (10 of 95 adenomas) and 11.8% (CI, 4.4% to 23.9%) (6 of 51 adenomas), respectively. The 10 patients with missed adenomas 8 mm or greater represented 12.2% (10 of 82 patients) of all patients with neoplasms of this size or greater; the 6 patients with missed adenomas 8 mm or greater represented 12.5% of all patients with neoplasms 10 mm or greater. Table. Characteristics of Neoplasms Missed at Prospective Colonoscopic Evaluation Seventeen (81.0%) of the 21 unblinded neoplasms 6 mm or greater were tubular adenomas, 3 (14.3%) were tubulovillous adenomas, and 1 (4.8%) was an adenocarcinoma. Seven (33.3%) of the 21 unblinded polyps were classified as advanced lesions (that is, size 10 mm or high-grade dysplasia, prominent villous component, or focus of malignancy). There were 15 sessile lesions, 4 pedunculated lesions, and 2 flat les


BACKGROUND
The pathogenesis of inflammatory bowel disease (IBD), is related to the effect of fungal presence in the gastrointestinal tract (GI) on IBD development.

MATERIAL/METHODS
One hundred twenty-six patients underwent mycological investigation. We analyzed of the occurrence of fungal infection in the clinical material collected from the GI tract of patients with IBD and control groups. We assessed fungal flora transmission from the oral cavity to further segments of the GI tract based on comparative studies of genotypes of fungal strains. The studies were carried out using conventional methods. The fungal genotypes were determined with the PCR-RAPD method.

RESULTS
Of 407 samples, 220 of them had fungi. The most frequently isolated species was C. albicans in patients with IBD and in control group, respectively 84.4% and 81%. Analysis of the streak patterns of the products of the PCR-RAPD reaction carried out for C. albicans strains isolated from the material collected from 10 patients, showed 100% affinity between the strains cultivated from the same patient. Genetic affinity between the strains was confirmed in 3 primers used in the examination.

CONCLUSIONS
The presence of fungi in the oral cavity of patients with IBD may affect more frequent colonization of the colonic mucosa in the active phase of disease. Genetic affinity of C. albicans strains indicates the possibility of fungal transmission from the oral cavity to further segments of the GI tract.


Optical Character Recognition (OCR) are widely utilized in two-dimensional (2D) image, but can not be utilized in the three-dimensional (3D) model. The direct method gets the screenshot of 3D text model and save it as a BMP image. But this way will make the image has serious distortion. In this paper, based on texture mapping principle, using geometric knowledge to convert a 3D model into 2D images. Experimental result shows that the OCR rate is high, efficiently and accurately restore the original 3D model.


Abstract : The steel chosen for the pressure hull of the Collins class submarine has undergone evaluation to compare the crack arrest fracture toughness, K(Ia), of the parent plate with that of weld metal and heat affected zone. The tests were conducted over a range of subzero temperatures on specimens slightly outside the ASTM standard test method specimen configuration. Shallow face grooved specimens were used to vary the propagating crack velocity from that of non face grooved specimens and determine if K(Ia), is sensitive to changes in crack velocity. The weld metal, heat affected zone (HAZ) and parent plate were assessed to determine if the welding process had a deleterious effect on the crack arrest properties of this particular steel. Tests on each of these regions revealed that, for the combination of parent plate, welding procedure and consumables, no adverse effect on crack arrest properties was encountered. Crack arrest fracture toughness of the weld metal and HAZ was superior to that of the parent plate at comparable temperatures.


According to some embodiments, the treatment methods of the subject is provided with symptoms associated with diabetes or diabetes. The method liver (e.g., sympathetic hepatic nerve plexus) vascular (e.g., hepatic artery) having a peripheral nerves perform innervation comprising delivering neuromodulatory catheter within. The method also includes mechanical compression, by delivery or fluid delivery of energy, regulation of neuronal (e.g., division, resection, stimulus) to carry out. .Field


This paper describes a general-aviation digital avionics flight-test facility being jointly developed by the Flight Dynamics Laboratory of Princeton University and NASA/Langley Research Center. This facility consists of the Princeton avionics research aircraft (ARA) and NASA/Langley's digital avionics research (DARE) system. The ARA is a fully instrumented five-degree-of-freedom fly-by-wire aircraft. The DARE system contains a state-of-the-art flight computer system and receiving equipment that permits use of the NASA/Wallops Flight Center's position-tracking ground-based display-generation and ground-to-air digital-data-link equipment. The DARE/ARA system will be used for flight evaluation of advanced control, guidance, and display concepts developed as part of NASA/Langley Research Center's general aviation terminal area operations program.


AIM To study the isolation and in vitro culture of rabbit's bone mesenchymal stem cells (BMSCs) and adipose stromal stem cells (ASSCs) and the use of both BMSCs and ASSCs cells in nuclear transfer (NT) to produce totipotent blastocysts. METHODS Both cell lines were derived from New Zealand rabbits and used as donor cells. The cell lines were cultured as a low cell density suspension in the Dulbecco's modified Eagle's medium (DMEM) and 150 mL·L -1 fetal calf serum (FCS) for 7 d before use in nuclear transfer. Direct intracystplasm microinjection techniques were used to reconstruct one cell embryos. Sire differences were noted in the ability of both BMSCs and ASSCs to form blastocysts. RESULTS A total of 986 nuclear transfer clones were made by fusing both BMSCs and ASSCs cells nuclei into enucleated oocytes. After culture of the clones for 7 d in vitro , 88 (16.9%) and 73 (15.7%) of those fused with BMSCs and ASSCs cells nuclei became blastocysts ( P 0.05 , Yates corrected). CONCLUSION BMSCs and ASSCs can be used as the NT donor cells to form blastocysts. There is no significant difference in blastocyst development rate (BDR) between them.


The neon–water system has been investigated by abinitio quantum-chemical calculations. The potential-energy surface (PES) for the 1:1 Ne–H2O interaction has been scanned at the MP2(full) level, with the 6-311++G(3df,2pd) basis set augmented with bond functions located midway between Ne and O. The most stable neon–water arrangement has r = 320 pm, θ = 120°, with a counterpoise-corrected binding energy of −0.54 kJ mol−1. The PES is otherwise quite flat (with binding energies of ca. −0.4 kJ mol−1) for all θ values if r > ca. 310 pm. The off-plane, perpendicular approach is unfavourable. NMR shielding and the electric field gradient at all nuclei show only very small changes with respect to the isolated components.


Both undesirable walking environment and external perturbations will cause the ZMP(zero moment point) error and affect the walking stability of the humanoid robot.Since ZMP is affected by angles of all robot joints,it is difficult to achieve good walking-control performance if only correcting the ankle or hip angles of the support leg.Therefore,considering the influence of all joint angles on ZMP,the way to calculate the CoM(center of mass) position displacement of robot is studied by fuzzy controller based on ZMP error.Then angle corrections of all joints to match the CoM position displacement are computed by using quadratic programming and CoM Jacobian matrix.The simulation results show that by this method,the desired ZMP trajectory can be tracked very well,and the walking stability margin is improved,which helps the humanoid robot walk stably.


It's been 100 years since Gibson and Tyndall formally proposed the values that were standardized a year later as the CIE spectral luminous efficiency function for photopic vision, V(λ). The 1920s was a decade when several new computing machines were introduced, but before the first introduction of modern electronic computers in the 1940s. Calculations involving the nascent lumen were likely done by hand and were then at the forefront of lighting science. By the 1960s, methods to calculate average horizontal illuminance, such as the zonal cavity method, were available and the subject of scientific research to understand error levels and extend applicability to new situations. With the increasing availability of personal computers in the 1980s and 1990s, new lighting software based on ray tracing models, radiosity models or a combination was introduced to ease the burden of computing lighting quantities, extend computational capabilities to a much wider range of applications and offer rendered images. The performance of lighting calculation software has continued to improve, and in the last several years, it has begun to include better modelling of spectral quantities as well. There's still room to improve the speed, accuracy and utility of lighting calculations, and the five articles in this issue all relate to this aspect of lighting research. Yoshizawa et al. present a new model for spatial lighting calculations and visualizations, Photon Flow, which focuses on the light field itself rather than surface-bound quantities. Chen et al. propose a grayscale luminance function to determine average luminance and the spatial luminance coefficient. Tsesmelis et al. propose a neural network architecture, DeepLux, for predicting illuminance of indoor scenes in real time. The final two articles focus on spectral power distributions (SPDs). Lokesh et al. present work that also applies neural networks, but their use is to predict changes to SPDs over time. Finally, Royer et al. document a new algorithm for computing large sets of metamers for colour-mixed LED systems. In the coming years, it will be interesting to follow how these methods, and others that are sure to follow, will influence lighting practice and lighting outcomes. Artificial intelligence, machine learning and data science have become key elements of many scientific fields, but the lighting profession – which is not known for rapid change – may have to look outside itself to effectively integrate new metrics, methods, workflows and business models. As Leland Curtis suggests in this issue's opinion, the future of lighting practice may be very different than what is common today, with a focus on delivering scalable digital technology products instead of projects. I wonder if Gibson and Tyndall, or any of the other researchers whose data contributed to the definition of the lumen, envisioned a future where calculation software could provide realtime, accurate, photorealistic rendering of light in a space, and the associated improvements to lighting design practice, lighting quality, energy efficiency – essentially all aspects of the lighting profession. Likewise, from our current viewpoint, it is difficult to imagine how the research of today can further improve the built environment in the next century. Near-term progress may seem slow, but I believe that the work being done in this decade, and highlighted in this issue, may one day be seen as a turning point from which a new generation of lighting tools emerged.


This article is mainly to give an introduction of the application of the software SPSS12.0 in animal science.It includes several useful statistical processing methods such as Sample Test,Compare Means,Analysis of Variance,Regression Analysis,Partial Correlation Analysis,Curve Estimation,etc.


Lumbosacral defect after instrumented spinal fusion is a serious complication that challenges orthopedic surgeons. We report a case of a 63-year-old woman who underwent instrumented thoracolumbosacral correction and reconstruction surgery. Deep operative wound infection and dehiscence occurred. The wound cultures yielded Staphylococcus aureus, which was sensitive to oxacillin. After extensive debridement and negative pressure vacuum-assisted closure therapy, the soft tissue reconstruction team of our department was consulted for her irreparable lumbosacral wound defect with partial implant exposure. A pedicled superior gluteal artery perforator flap was used as a salvage procedure for lumbosacral soft tissue reconstruction. She was satisfied with the surgical results and returned to her daily activities with good recovery.


The PSA is committed to fixing the problems of HMRs so that the service can continue. We feel the much-criticised 'Chris Freeman Model' deserves support.


In response to the regime breakdowns in some Arab countries, the European Commission suggested a 'New Partnership for Democracy and Shared Prosperity with the Southern Mediterranean.' When explaining this strategy in an article published in The New York Times on 25 February 2011, Catherine Ashton (2011), then High Representative for Foreign Affairs and Security Policy, emphasised that the European Union (EU) is

determined to help Tunisia, Egypt and other countries not just to start their journey toward democracy, but to complete it […] That will involve detailed, unglamorous, work on the ground – with civil servants, local communities, the police, army and judiciary – laying the foundations of deep democracy and then building it up, brick-by-brick.


In this paper,a CMOS image sensor interface IP integrated in SOC chip with ARC600 core is presented.It analyzes two kinds of the CMOS sensor output timing,especially the ITU-656 like mode,and how to design CMOS sensor interface in SOC is introduced.It synchronizes the sensor data to the internal clock,separates the data into 3 channels and loaded into internal buffer.Finally it transfer to the external memory by AHB master interface with DMA mode are presented.It generates the video data for back-end image processing.After verification,it can reach the bandwidth when refresh QVGA in dynamic mode.So it can satisfy the marketing.


In this paper, an off-line synthesis approach to robust constrained model predictive control is presented. Most of the computational burdens are reduced by computing off-line a sequence of state feedback control laws that corresponds to a sequence of polyhedral invariant sets. At each sampling time, the smallest polyhedral invariant set containing the currently measured state is determined and the corresponding state feedback control law is implemented to the process. The proposed algorithm is compared with an ellipsoidal off-line robust model predictive control algorithm. The results show that the proposed algorithm can achieve better control performance. Moreover, a significantly larger feasible region is obtained. The controller design is illustrated with an example of continuous stirred-tank reactor.


The paper approaches the question whether a distinctive European answer to the challenges of globalization, neo-liberalism, and social disintegration is both available and feasible. After describing the influence the American model of capital accumulation exerted on Europe's economic, social, and cultural development, the paper argues that, in spite of the hegemonic project the United States pursued after WW II, viable national variants of capitalism developed in Western Europe and Japan. With the exhaustion of the Fordist model of accumulation in the 70s and 80s a new constellation arises that threatens the social compromise the European welfare state is based upon. The globalization of production and the politics and ideology of neo-liberalism work hand in hand, producing a shift in the balance of social forces, decreasing national capacities of economic regulation, growing inequality, and the marginalisation of a growing number of social groups. Although there is a convergence of fundamental trends in regard of the modes of accumulation, we are stuck in a highly ambiguous and indeterminate situation. The erosion of national particularities does not lead to total homogeneity, neither inside the triad of USA, Japan and Europe nor inside the European Union. The crises of the traditional welfare state in Europe can only be overcome if a new, independent model of »Social Europe« will be constructed. In doing so Europe faces a dilemma: Only if it manages to overcome neo-liberal policies and develop a common vision of the future it will gain the freedom of action that is needed for such an endeavor and that is lacking at the national level.


Karl Marx's essay, "On the Jewish Question," is commonly read as a critique of liberalism and not for what Marx has to say about Jews and Judaism. The author of this article argues that so narrow a reading is unfortunate, in part because Marx's anti-semitic slurs need to be challenged but also because Marx's analysis of the Jewish question itself adds to an understanding of his notion of freedom.


According to OECD statistics, in 2003–2013 annual incidence of job displacement varied from 1% to 7% of total number of wage and salary workers aged 20–64. Labour reallocation is a necessary part of labor market flexibility and economic growth however worker displacement generally also leads to an increase in unemployment and to a decrease in the income of those dismissed. Therefore, a set of measures to mitigate the negative consequences of this process is becoming an important direction of labor market policy. Significant cross-country differences in the ratios of re-employment and the size of wage gaps between jobs indicate that a well-designed and effective labor market measures, as well as properly "tuned" institutions, can significantly reduce the social risks of layoffs. Employees of obsolete professions who require serious professional retraining are in the group of primary risk after the displacement. Given the increasing dynamism and flexibility of the labor market throughout the world, the development of a more targeted system of financial support for the dismissed which involves coordinating the payment of benefits of various types, as well as taking into account the interests of vulnerable workers who do not have time to gain the tenure necessary to participate in the voluntary insurance program, is needed. Present study outlines the main policies for mass layoffs in OECD countries. Particular attention is paid to the characteristics of the system of financial support for the displaced workers, including the specifics of unemployment benefits and severance pay, as well as the configuration of active programs in the labor market and the practices of the public employment service.


In this study, we developed a hybrid deep learning (DL) model, which is one of the first interpretable hybrid DL models with Inception modules, to give a descriptive prediction of drug side‐effects. The model consists of a graph convolutional neural network (GCNN) with Inception modules to allow more efficient learning of drug molecular features and bidirectional long short‐term memory (BiLSTM) recurrent neural networks to associate drug structure with its associated side effects. The outputs from the two networks (GCNN and BiLSTM) are then concatenated and a fully connected network is used to predict the side effects of drugs. Our model achieves an AUC score of 0.846 irrespective of what classification threshold is chosen. It has a precision score of 0.925 and the Bilingual Evaluation Understudy (BLEU) scores obtained were 0.973, 0.938, 0.927, and 0.318 which show significant achievements despite the fact that a small drug data set is used for adverse drug reaction (ADR) prediction. Moreover, the model is capable of accurately structuring correct words to describe drug side‐effects and associates them with its drug name and molecular structure. The predicted drug structure and ADR relation will provide a reference for preclinical safety pharmacology studies and facilitate the identification of ADRs during early phases of drug development. It can also help detect unknown ADRs embedded in existing drugs, hence contributing significantly to the science of pharmacovigilance.


: Severe mid-cervical contusion injury causes profound deficits throughout the respiratory motor system which last from acute to chronic time points post injury. Here we use chondroitinase ABC (ChABC) to digest chondroitin sulphate proteoglycans (CSPGs) within the extracellular matrix (ECM) surrounding the respiratory system at both acute and chronic time points post injury to explore whether augmentation of plasticity can recover normal motor function. We demonstrate that, regardless of time post injury or treatment application, the lesion cavity remains consistent showing little regeneration or neuroprotection within our model. However, through electromyography (EMG) recordings of multiple inspiratory muscles, we show that application of the enzyme at chronic time points post injury initiates the recovery of normal breathing in previously paralysed respiratory muscles. This reduced the need for compensatory activity throughout the motor system. Application of ChABC at acute time points recovered only modest amounts of respiratory function. To further understand this effect, we assessed the anatomical mechanism of this recovery. Increased EMG activity in previously paralyzed muscles was brought about by activation of spared bulbospinal pathways through the site of injury and/or sprouting of spared serotonergic fibres from the contralateral side of the cord. Accordingly, we demonstrate that alterations to the ECM and augmentation of plasticity at chronic time points post cervical contusion can cause functional recovery the respiratory motor system and reveal mechanistic evidence of the pathways which govern this effect. The present study shows the long-term functional deficits caused by unilateral mid-cervical contusion injury. We demonstrate that, while endogenous plasticity and compensatory function are evident, these are not sufficient to facilitate a robust return of function. We hypothesised that enhancement of plasticity through an exogenously applied treatment strategy would facilitate recovery of respiratory motor function following contusion injury. Indeed, this study provides the first direct comparison of a plasticity inducing treatment strategy for respiratory motor dysfunction at both acute and chronic time points following cervical contusion injury. Here we show that ChABC treatment applied at chronic stages following cervical contusion injury can mediate recovery of 'normal' activity within the previously compromised ipsilateral hemidiaphragm, reducing the need for compensatory activity in the other muscles. Alternatively, acute application of the drug only marginally aids recovery of respiratory motor function. The mechanism of this recovery is, in part, mediated through serotonergic sprouting of neuronal pathways. At chronic time points post contusion, this treatment induced recovery partially occurs through the contused respiratory fibres but is also governed through the activation of latent pathways, or sprouting, modulatory axons from the undamaged contralateral side of the spinal cord. These data show that enhancement of plasticity can facilitate recovery of the respiratory motor system following severe mid-cervical contusion if applied at chronic time points following trauma.


A new micro-size copper hydrogen phosphate (CHP) synthesized by the emulsion method combined with a monomeric ruthenium species was found to be a very effective catalyst for the selective oxidation of alcohols. Several kinds of alcohols were transformed into the corresponding aldehydes or ketones over the RuCHP catalyst by oxygen under very mild conditions. The results showed that the CHP material was perfect as a catalyst support due to its high ion-exchange ability and adsorption capacity.


We establish that the spin-3/2 AKLT model on the honeycomb lattice has a nonzero spectral gap. We use the relation between the anticommutator of two projectors and their sum, and apply it to related AKLT projectors that occupy plaquettes or other extended regions. We analytically reduce the complexity in the resulting eigenvalue problem and use a Lanczos numerical method to show that the required inequality for the nonzero spectral gap holds. This approach is also successfuly applied to several other spin-3/2 AKLT models on degree-3 semiregular tilings, such as the squareoctagon, star and cross lattices, where the complexity is low enough that exact diagonalization can be used instead of the Lanczos method. In addition, we also close the previously open cases in the singly decorated honeycomb and square lattices.


Little is known about the evolution of epilepsy in individuals with tuberous sclerosis complex (TSC) in adulthood. This study aims at describing the characteristics of epilepsy in adult TSC patients attending a single multidisciplinary clinic.


The high penetration of renewables envisaged for future power systems will significantly increase the need for flexible operational measures and generation technologies, whose associated investment decisions must be properly planned in the long term. To achieve this, expansion models will need to incorporate unit commitment constraints, which can result in large scale MILP problems that require significant computational resources to be solved. In this context, this paper proposes a novel Dantzig–Wolfe eywords: olumn generation eneration expansion planning lexibility enewable energy integration nit commitment decomposition and a column generation approach to reduce the computational burden and overcome intractability. We demonstrate through multiple case studies that the proposed approach outperforms direct application of commercial solvers, significantly reducing both computational times and memory usage. Using the Chilean power system as a reference case, we also confirm and highlight the importance of considering unit commitment constraints in generation expansion models. © 2016 Elsevier B.V. All rights reserved.


Acquired immune deficiency syndrome (AIDS)‐related diffuse large B cell lymphoma (AR‐DLBCL) is a rare disease with a high risk of mortality. There is no specific prognostic model for patients with AR‐DLBCL. A total of 100 patients diagnosed with AR‐DLBCL were enrolled in our study. Clinical features and prognostic factors for overall survival (OS) and progression‐free survival (PFS) were evaluated by univariate and multivariate analyses. Central nervous system (CNS) involvement, opportunistic infection (OI) at lymphoma diagnosis, and elevated lactate dehydrogenase (LDH) were selected to construct the OS model; CNS involvement, OI at lymphoma diagnosis, elevated LDH, and over four chemotherapy cycles were selected to construct the PFS model. The area under the curve and C‐index of GZMU OS and PFS models were 0.786/0.712; 0.829/0.733, respectively. The models we constructed showed better risk stratification than International Prognostic Index (IPI), age‐adjusted IPI, and National Comprehensive Cancer Network‐IPI. Furthermore, in combined cohort, the Hosmer−Lemeshow test showed that the models were good fits (OS: p = 0.8244; PFS: p = 0.9968) and the decision curve analysis demonstrated a significantly better net benefit. The prognostic efficacy of the proposed models was validated independently and outperformed the currently available prognostic tools. These novel prognostic models will help to tackle a clinically relevant unmet need.


The aim of this study was to investigate the effects of a planned exercise program and lectures followed by a brochure containing the nutrients arranged by quality on measured components of health-related physical fitness.The applied treatments positively affected the restructuring of body composition by reducing the relative amount of fat tissue in the body, local muscular endurance of upperbody, and aerobic endurance.The effects of the treatment depend on the level of control and self-control more than on the length of the treatment, while the level of control (and especially self-control) can be improved by increasing the knowledge about the association of health-related physical fitness and health, with given practical solutions. In that regard, the agencies should provide exercise programs and physical activities for their employees but also develop the strategies for a work-place health promotion that would steer the police officers(POs) and their families towards the involvement in healthy lifestyle. This research is part of the National Scientific Project ―Effects of applied physical activity on locomotor, metabolic, psychological, social and educational status of the population of the Republic of Serbia‖, No. ID III 47015, and it is financed by the Ministry of Education, Science and Technological Development of the Republic of Serbia DOI: 10.5937/bezbednost1902028K


complex. Thebrucella organism contains a large numberofother antigenically distinct components. Thebiological significance of some ofthese antigens hasbeendemonstrated byshowing that serafrominfected cattle haveprecipitins tothese components. Theseserarevealed up toseven distinct lines inimmunoelectrophoresis with a protein-rich antigen mixture prepared fromrough strain B.abortus 45/20, whereas serafromstrain 19-vaccinated cattle didnotreveal these lines at4ormore monthsafter vaccination. Monospecific antisera were prepared against sixantigens inthis mixture, andthepurification oftwoofthembyantibody affinity chromatography isdescribed.


We present evidence for the crossover between creep of individual vortices and collective creep of vortex bundles from measurements of the relaxation of the persistent currents in YBa[sub 2]Cu[sub 3]O[sub 7] single crystals over long periods of time. In the single-vortex regime at low fields the relaxation is fast and is characterized by an exponent [mu][congruent]0.16, as predicted in the collective-creep scenario. With increasing field, collective bundling of vortices induces a slowdown of the relaxation, with a maximum [mu][congruent]1.4. At even higher fields, [mu] decreases again to about 1 as the size of the bundles grows.


2 h after the last provocative dose under observation at the allergy center. The patient developed systemic urticaria and angioedema of the Hps and hands about 2 h after the administration of lOmg of tartrazine. Symptoms were easily controlled by antihistamine therapy. All other substances were tolerated. The labels of several brands of tuna canned in olive oil were scrutinized: none reported tartrazine among the ingredients. Nonetheless, the causative role of canned tuna was unequivocable in this patient, and true fish allergy was excluded by SPT and oral challenge with fresh tuna. A nonspecific reaction to tartrazine is possible but unlikely. Thus, the only reasonable explanation of these findings is that significant amounts of this azo dye are present (but not declared) in some commercial preparations of tuna canned in olive oil; in effect, fish is included among foods to which azo dyes and benzoates are often added (1). It remains unclear why all the episodes of angioedema followed the ingestion of canned tuna in this patient; differences in tartrazine content among various preserved foods, as well as the patient's alimentary habits, might explain this effect. Food-additive intolerance should always be considered in patients who experience repeated episodes of urticaria/angioedema after the ingestion of specific commercial food preparations, even if these are generally considered additive-free.


Introduction. It is well known that social contact patterns differ from country to country. This variation coincides with significant socioeconomic heterogeneity that complicates the design of effective non-pharmaceutical interventions. This study examined how socioeconomic heterogeneity in selected African countries might be factored in to explain better social contact mix patterns between countries. Methods. We used a standardized contact matrix for 32 African countries, estimated in [31]. We scaled the matrices using an epidemic model from [34]. We also analyzed aggregated data from the World Bank country website. The data includes 28 variables; social, economic, environmental, institutional, governance, health and well-being, education, gender inequality, and other development-related indicators describing countries. Principal components analysis was used to visualize socioeconomic similarities between countries and identify the indicators for maximum variation. The (2D)2 PC A approach was used to reduce the dimension of the synthetic contact matrices for each country to avoid the dimensionality curse. Agglomerative hierarchical clustering was then used to identify groups of countries with similar social patterns, taking into account the countrys socioeconomic performance. Results. Our model yielded four meaningful clusters, each with a few distinguishing features. Social contacts varied between groups but were generally similar within each set. The countrys socioeconomic performance influenced the clusters. Conclusions. Our results suggest that integrating socioeconomic factors into social contacts can better explain infectious disease transmission dynamics and that similar interventions can be implemented in countries within the cluster.


Abstract : This first VCS symposium was sponsored by the Air Force System Command's Aerospace Medical Division (AMD) at Brooks AFB, Texas, and by AMD's laboratory which has promoted Air Force VCS development and application work, the Aerospace Medical Research Laboratory from Wright-Patterson AFB, Ohio. Participants and papers from DOD agencies and industry brought together the major VCS ideas as of November 1972. A visually-coupled system integrates the natural visual and motor skills of an operator with the machine he is controlling. The VCS operator visually searches for, finds, and tracks an object of interest. His line-of-sight is measured and used to aim sensors and/or weapons toward the object. Information related to his visual/motor task from sensors, weapons, or central data sources is fed back directly to his vision by special displays so as to enhance his task performance. Currently a helmet-mounted sight (HMS) is used to measure head position and line-of-sight and a helmet-mounted display (HMD) is used to feed back information to the eye. R and D efforts are underway to reduce size, weight, and increase the performance of future VCS devices. Such advanced VCS concepts as eye position sensing/control and dual field of view sensors/displays are being explored for future improved man-machine integration. (Author)