In this paper, based on the emerging SDN (Software-Defined Networking) paradigm, we present our on-going work on realizing a programmable switching node supporting in-network processing for multi-screen content consumption with balancing its use of computing/networking resources.


Essential thrombocythemia (ET) is a chronic myeloproliferative disorder, characterized by increased proliferation of megakaryocytes and elevated platelet counts that usually occurs sporadically. We report a family with 7 affected individuals in three generations, including one individual with a phenotype resembling polycythemia vera, a related disorder. Megakaryocyte (CFU-MK) colony formation occurred in the absence of added cytokines in cultures of peripheral blood from affected family members. Some reports of familial ET have identified mutations in the genes coding for thrombopoietin (TPO), the cytokine that primarily regulates platelet production and its receptor, c-MPL. In this family, the MPL gene was excluded by linkage analysis. Although TPO levels were elevated in most affected family members and evidence for linkage was found between the disease and TPO (𝛉 = 0.0, Zmax = 3.0), a TPO mutation was not identified by DNA sequencing. The JAK2 V617F mutation that has been associated with 50% of sporadic cases of ET was identified as a somatic mutation in the peripheral blood of the two most clinically affected family members. These patients also had the most elevated TPO levels, raising the possibility of an association between JAK2 and TPO production. Further study of familial myeloproliferative diseases will help elucidate the initiating genetic events underlying ET.


This review might consist of one sentence: 'Whatever type of epidemiologist you are, whether you are in public health, or in cancer, or in cardiovascular, or clinical, or even when you are a pure methodologist or statistician interacting with epidemiologists—just download this book.' The pdf is free from the publisher's site; the hardback version comes at a price, but is beautifully rendered by a publisher who specializes in history and ancient texts. By reading it, you will gain a tremendous amount of knowledge about health and diseases in populations: how health and diseases wax and wane, over time and between countries, over political and social systems. Yes, it is history, but it is not merely history: the author scrupulously discusses rivalling theories about the proximate and the ultimate causes of changes in health, differences in changes in health, rise and fall of diseases—from homicide to breast cancer, from Russia and Albania to Spain and Norway, covering two to three centuries of the whole of geographical Europe. Moreover, it is crammed with facts, graphs, and almost on each page points to further data to consult, or further reading. Also, the author clearly indicates what the 'white areas' are in our understanding and what additional data or research might be needed. While the author is clearly passionate, intellectually and socially, about the health of the public, the epidemiologic rigor of reasoning comes first. One example: he indicates how almost all studies find a perfect relationship between more democratic (capitalist?) state arrangements and a better health for the public at large. However, he continues that this relationship holds only cross-sectionally, and is less clear longitudinally—that is: 'changes' into a more democratic state, or the reverse, have little correlation with a beneficial or an adverse change in the health of the public. Thus, the author concludes that the apparent symbiosis of health and democracy must be confounded. He points out how a transition to both fascist and communist dictatorships in the early twentieth century resulted in many a swift and dramatic improvement of health—and, in reverse, how in Russia the (temporary) attempts towards a more western democratic state of affairs in the late twentieth century brought about a public health disaster. However much engaged the author is in promoting public health—an engagement that shows on every page of the book—he never loses his analytical strictness: thus, when longitudinal changes do not match cross-sectional findings, he wonders what is going wrong when making too hasty conclusions. The book is therefore a great joy to read, perhaps not in one breath from cover to cover—as the information density is high—but piecemeal. Known concepts and known stories are reviewed, viewed from a different angle, and some stories pierced. For instance, when writing about violent deaths in war, the author points out that, yes, the number of wars has continued to greatly diminish over the past centuries in Europe, which seems a great relief and achievement of mankind—but the wars of the twentieth century took the most lives ever, also relative to the sizes of the populations affected. Let me conclude with my initial phrase: just download and read. And good chances that you will be so captivated as to want your personal hardback copy.


Aim: Organ donation rate in India is very poor. The factors contributing to donating and not donating an organ is not well known. Hence, the present study was conducted to identify the perceived barrier and facilitator of organ donation among general public of Puducherry, India. Method: A cross sectional explorative study was undertaken with a sample of 400 eligible subjects from the general public of puducherry. Each participant underwent a face to face interview with the help of a structured questionnaire; data collected was analyzed using appropriate descriptive and inferential statics in SPSS. Result: Of the 400 subjects interviewed, the most common perceived barriers identified were opposition from family (82.8%) and fear (72.4%). The most common perceived facilitators were thought that organ donation would save someone's life (95.9%) and sense of improved humanity (95%). While associating the public intention to donate organ with select variables only educational status was found to be positively associated (p =0.001). Conclusion: From the available scientific evidence it is conducted that the knowledge of organ donation remain still poor and the identified barriers and facilitators should be taken in the account while motivating the general public to donate organ in future.


$EVWUDFW Relying fully on manual effort in generating metadata is not the way to go: we need automation of this process, as much as possible, without losing the "quality" of the metadata. In this paper we report on our experiences with automatic metadata generation. We briefly outline the first version of our framework for automatic metadata generation and then report on some lessons we learned. These lessons resulted in a redesign of the framework. An important aspect in this redesign is the bottom-up strategy, instead of the topdown design we used before. This means that we start with an abstract specification that is then made concrete in implementations. This should allow for interoperability between installations that do (part of) the metadata generation. The redesigned framework is used in a case study that also extends the metadata generation part by allowing for search and retrieval of the generated metadata. We also report on an evaluation experiment that we set up for this case study, which points out that the automatically generated metadata has a similar level of quality than manually generated records present in the ARIADNE repository. Finally we conclude with some future work.


This paper will discuss the pragmatism of William James is an attempt to solve the problem 'Why need the theory of truth for social problem?" (Research Problem) The answer to this question will be provided by showing that human society needs not only the truth is relative but also practical consequences to human purpose and evaluation. (Tentative Solution) This paper will contribute to the criterion of truth in James' theory and truth is what works or has good experimental results. It is necessary for the practical life in human society. (Contribution)


An embodiment of this invention is an information storage system comprising a plurality of storage systems connected to be able to communicate. Each of the plurality of storage systems includes default storage system identification information which is the same to the plurality of storage systems, common volume identification information for uniquely identifying volumes provided by the plurality of storage systems to a host computer among the plurality of storage systems, and a controller configured to return the default storage system identification information to the host computer in response to a request from the host computer and to process a read or write request to a volume accompanying the common volume identification information from the host computer.


The emerging of cross-border internet banking is challenging the supervision and management of banking risks.Therefore the Basel Committee has issued a series of papers,defining the cross-border internet banking activities and demanding both the banks and the supervisors to supervise them.Also,the Basel Committee holds that: the supervisory notions should be innovated;cooperative supervision should be emphasized;internal supervision should be integrated with external supervision;the content of supervision should be expanded;the information should be disclosed sufficiently.Based on the suggestions of the Basel Committee,this article points out that we should learn from the experiences of Basel Committee system,transform our supervisory ideas and conform to international practices,perfect the system of bank exiting the market,and pay more attention to the establishment of "software" and "hardware" in banking.


Sulfur abundances and metallic iron abundances in 18 Apollo 12 mare basalts were determined. No correlation between sulfur abundance and metallic iron content was detected; metallic iron abundances are not primarily caused by S loss. Sulfur abundances, directly related to the bulk composition of the rocks and especially to the TiO2 content, increase with increasing degrees of fractionation and appear to result from S concentration in the melts during fractionation. Unlike the Apollo 17 melts, the Apollo 12 melts were unsaturated with respect to sulfide. Composition appears to control S content for Apollo 17 basalts, and cumulus processes may cause Fe-FeS enrichment.


This research aimed to describe the comparison news frame on Amnesty Tax policy in the first period with Viva.co.id and Kompas.com online media model Zhondang Pan and Gerald M. Kosicki. This study aimed to describe the comparison frame pemberitaaan Amnesty Tax policy in the first period with Viva.co.id and Kompas.com online media model Zhondang Pan and Gerald M. Kosick. This type of research used in this research is descriptive qualitative. Data collection technique used REMEDY stage, the stage of data analysis, and interpretation phase. And data analysis techniques. The results showed framing Kompas.com against tax amnesty tax amnesty is seen as an effort to help grow the economy of Indonesia, while framing Viva.co.id looking at tax amnesty as an alternative effort to help the Indonesian economy but the policy has many shortcomings that need a lot of socialization and revision. Key words: framing analysis, tax amnesty, Kompas.com and Viva.co.id


Research on crime news continues to generate scholarly interest, particularly in the realm of social constructionism. From this perspective, researchers have documented the process by which crime is shaped into news—especially the pivotal role played by law enforcement officials. In this study, the authors contribute to this area of inquiry by administering a content analysis of 105 feature articles on crime published in four national newspapers between 1992 and 1995. In addition to exploring the topics of crime, they systematically examined the nature of quotes offered by two groups of experts, namely, state managers (e.g., police and politicians) and intellectuals (e.g., professors). Their findings support previous research demonstrating the media's heavy reliance on law enforcement officials in formulating primary definitions of crime. The significance of primary definitions of crime within the context of the dominant ideology and moral panic is discussed at length.


Education and practical training crisis management members are a topical issue nowadays. The paper deals with the perspectives and possibilities of "smart solutions" to education for crisis management staff. Currently, there is a large number of simulation tools, which notes that they are suitable for practical training of crisis management staff. The first part of the paper is focused on the introduction of the technology simulation tools. The simulators aim is to create a realistic environment for the practical training of extending units of crisis staff. The second part of the paper concerns the possibilities of using the simulation technology to the education process. The aim of this section is to introduce the practical capabilities and potential of the simulation programs for practical training of crisis management staff. Keywords—Crisis management staff, computer simulation, software, technological education.


Physician offices are commonly assumed to be comparatively scarce in low income and black urban areas. To test this assumption, the number of physician offices in each census tract in the city of Pittsburgh was cross tabulated against median income levels. This cursory analysis indicated that, in contradiction to the conventional wisdom, income level and office frequency were negatively correlated. Multiple regression techniques were then employed to test a model of physician distribution within Pittsburgh that allowed the contribution of several determinants to be tested simultaneously. The results indicated that proximity to short term hospitals and the presence of large amounts of commercial zoning were the principal factors affecting physician office location. After controlling for these factors, the effect of median income of an area was found to be neutral, exerting no influence one way or the other, although there was a slight tendency for physicians to be scarce near concentrations of blacks.


The discipline of physicians is an issue of public trust. In the majority of Western countries, physician misconduct is self-governed at a state-wide or provincial level by physician licensing and regulatory associations. In the USA, this responsibility falls under the jurisdiction of state medical licensing boards. These state boards review complaints against physicians and investigate whether standards of care and professionalism have been upheld; they also decide upon specific punishments for misconduct, including fines, extra training and education, and licence suspension and revocation. However, there is no overarching federal standard with which each state regulatory board must comply, nor is there a unifying body that compares individual states and their quality standards and policies for physician disciplinary proceedings.

In this issue, Harris and Byhoff1 investigate physician misconduct cases using a US database of medical board disciplinary actions from 2010 to 2014. The authors report up to a fourfold variation in the annual rate of physician disciplinary actions between state medical boards. They also suggest potential explanations for such variability, such as variations in patient factors, physician factors and significant differences in the processes related to disciplinary proceedings by the individual medical boards. Ultimately, the authors recommend policies to improve standardisation and provide more consistent regulation to physicians in the name of public safety. Their findings underscore the timely issue of using physician discipline and misconduct as an extreme marker of physician quality. Importantly, it is among the first to highlight such variability across jurisdictions.

Historically, investigations on physician misconduct have limited their focus to a state-wide or provincial level, or have centred on malpractice claims and lawsuits against physicians.2–9 Only a handful of studies have examined …


Abstract. According to hunting statistics in the last two decades, both the population numbers and harvesting of roe deer in Poland have been on the increase from 597000 to 876000 animals and from 158000 to 172000 harvested individuals, respectively. The number of roe deer reported by hunters are mainly based on guesswork, therefore the objective of the study was to verify the inventory of roe deer conducted by hunting clubs in the Myślibórz Forest District (north-western Poland) and to determine the sex ratio and age structure this species. The study area is including 86 small size forest complexes and covers 12990 ha. Roe deer number were determined over four years from 2002 to 2006. In sampling plots (February 2002) data from snow tracking and driving census showed significant correlation (r = 0.663, p = 0.003) between the relative population density (N/km) — independent variable and population density (N/1000 ha) - dependent variable. Roe deer snow tracks were counted during five days each year on 16 line transects (length 66.4 km) and the relative population densities (animal per km*day-1) for the whole study area were calculated. These indices were inserted into the regression formula that was obtained from sampling plots. It allowed to calculate the population density (N/1000 ha) and then roe deer numbers inhabiting the study area. Population density ranged from 300.1–319.0 individuals/1000 hectares of forest, and the differences between the four years of study were statistically insignificant. In summer, the sex ratio of the population was 1:1.4 in favour of females, and the autumn increment of young animals amounted to 70.2 fawns/100 does. The average population number of roe deer assessed for these four years was 3568 individuals and was more than two times higher than the average population size (n = 1670) given by hunters.


A discussion is given of excitons in molecular crystals using the analogy of the electron gas and the results are compared with those of Hall and Hopfield. Physical processes in which excitons are likely to be important are briefly reviewed.


In Japan, expenses for landfilling yield about 400 US$ per t of ash, which gives an incentive to reduce the amount of landfilled ash. At NIES (National Institute for Environmental Studies) in Tsuku ...


To solve the problem of increasing the efficiency of cleaning the exhaust air of painting chambers from fine particles, a separation device with elements of a square and rectangular shape has been developed and described by the principles of its operation. A method for calculating the design dimensions of the developed separation device is presented. Different versions of the height of the separation zone are considered, depending on the size of dispersed particles. It is shown that the device is able to capture particles smaller than 10 microns with an efficiency close to 100 %, provided they adhere to the walls. The peculiarity of the design of the separation device is that a set of small-diameter vortices is created, in which the flow regime is close to laminar, and to achieve large values of centrifugal force, it is not necessary to create high speeds in the crevices.


This paper describes concentrated discharges on polluted insulators in the laboratory and in the field. The authors have observed the concentrated discharges at the high-voltage laboratories in Stuttgart, Zittau, and Mannheim, Germany, and Wroclaw, Poland. The concentrated discharges were also documented under natural conditions. These discharges are very dangerous especially for high-voltage apparatus, bushings, and polymer insulators. It has been shown that due to uneven voltage distribution at very low surface conductivity, the concentrated discharges can ignite even under uniformly polluted and uniformly wetted insulators


Atmospheric emissions of sulphur and nitrogen oxides lead to the formation of acid rain, which, when deposited, can result in soil and water acidification. Cases of soil and water acidification have been reported in temperate climates, such as Europe, the United States and Asia. However, in semi-arid grassland areas, such as South Africa, where seasonal wetting and drying climatic cycles are experienced, the impacts of atmospheric deposition are expected to differ from those in temperate climatic zones. Hence, the purpose of this study was to determine the impacts of atmospheric deposition on soils and water in the semi-arid grassland areas of the South African Eastern Highlands. This was done by investigating the leaching characteristics and susceptibility to acidification, of soils exposed to atmospheric deposition in the Sandspruit Catchment, and to determine the influence of deposition on catchment water quality.
Soil samples were collected from a farm located within the Sandspruit Catchment, in the Vaal River basin, from two hillslope transects (WS and WM) at the crest and toe slope positions. Soils from the four sampling positions were subjected to aerated and non-aerated column leach tests, using distilled water (pH 7.05) and a simulated acid rain solution (pH 4.35). Leachate from each column was collected as fractions of pore volume aliquots and measurements for EC, pH and redox potential were conducted immediately after collection. Further analysis was conducted for base cations, metals and anions and the data presented as breakthrough curves.
Comparing the leaching characteristics of the two hillslope soils, both WS crest and toe soils result in leachate with higher EC values, indicating that there are more base cations and anions in WS soil column leachates than WM soil column leachates. The pH for WS soil column leachates remained in the alkaline to slightly acidic range, whilst that for WM soil columns was mostly in the slightly acidic range. This indicates that even after the addition of an acidic solution, the soil had the capacity to neutralise some of the acidity through CEC and exchangeable bases. Hence, the two invading liquids, at pH 4.35 and 7.05 resulted in similar leachate pH values ranging from 6.05 to 8.0. The level of aeration within the columns also determined the leaching characteristics of WS and WM soils. WS soil column leachates had lower redox potential values (below 0 mV), indicating reducing conditions, hence had a higher concentration of Mn in solution. On the other hand, the WM soil had higher redox potential values (greater than 150 mV), indicating oxidising conditions, hence the Mn concentrations in these columns was below detection limits.
Surface water samples were obtained from the farm catchment and sampling was extended to the quaternary scale, comprising tributaries downstream of the research site that feed into the Sandspruit River. The samples were taken on a seasonal basis between 2011 and 2012. The pH and EC of the samples was measured upon collection and further…


Norwegians have used high strength concrete for offshore structures in the North Sea since 1973. The critical demands of such concretes due to high strength, durability, and constructibility requirements, the magnitude of the structures, and the rate of construction, and the special cements and pozzolans, hydraulicallly processed sand, and refined superplasticizers and other chemical admixtures that have been developed are discussed in this paper. The paper discusses the areas of constructibility, cement, pozzolans such as silica fume, aggregates, chemical admixtures (water-reducing, retarding, accelerating).


Background and Objective:
PIVKA-II (Protein induced by vitamin K absence II) is an upcoming and promising new biological marker cited as having a definitive role in the early detection and diagnosis of hepatocellular carcinoma (HCC). Preliminary research shows PIVKA-II reference intervals (RIs) in serum to have substantial racial disparities globally.  Hence, this study aimed to determine the RIs and cut-off value of the serum PIVKA-II for the first time in healthy and patients with hepatocellular carcinoma in Pakistan.

Methods: This cross-sectional study comprised of 240 participants (120 diagnosed cases of HCC and 120 healthy individuals) registered at the Department of Chemical Pathology and Immunology, Chughtai Institute of Pathology, Lahore, Pakistan. The PIVKA-II serum level was analyzed using the Chemistry Analyzer through chemiluminescent micro-particle immunoassay (CMIA). The reference interval was subsequently established using the percentile method.

Results: In healthy Pakistani adults, the 95 percent reference interval for PIVKA-II was 15.55-43.03mAU/ml, and the cut-off was 148.81mAU/ml in HCC (hepatocellular carcinoma) cases. The male participants, exhibited higher PIVKA-II levels than the females (P < 0.002). There were no significant differences in the serum levels of  PIVKA-II with respect to age however variations were observed with respect to gender.
Conclusions:
Determination of the reference interval for serum PIVKA-II in healthy adult Pakistani individuals and a cut-off for HCC diagnosis emphasizes the growing need to establish and verify reference intervals of analytes at a larger scale in our population. Ideally all clinical laboratories should establish their own reference intervals.


Western medicine changed fundamentally during the Middle Ages, with farreaching effects on the development of the healing arts for centuries to come and ultimately to the present day. Medicine became an academic discipline. It established itself at the newly founded universities. Today, this position is taken for granted. It is widely acknowledged that an adequate diagnosis and treatment of the various human diseases calls for a highly differentiated theoretical foundation, on the basis of a comprehensive and sophisticated knowledge of physiological and pathological processes in the body. As soon as we widen our perspective and look at the many different cultures on our planet, in the past as in the present, however, we quickly see that Western culture with its appreciation of an "academic", theory-based, scientific medicine is exceptional. In all known cultures and societies there are diseases, and there are people who concern themselves with diagnosing and treating them. And in the vast majority of cultures, medical practice is guided by more or less complex ideas of the human body and its relation to the social, the natural, and the supernatural environment, and it is in the hands of people who are believed to possess special knowledge and skill in the area. Yet, on a global scale, the conviction that medical practice requires a comprehensive, written methodological and theoretical foundation and that a true doctor must be a "learned man" is not the rule but the exception. It is found only in the few so-called "advanced civilizations" that put special emphasis on the written word and book knowledge on the whole, civilizations which moreover, it has been shown, have sometimes had a mutual influence on each other. The German term for physician "Arzt", too, did not originally denote a studied, scholarly physician exclusively. The term likely derives from the Greek word "archiatros", which referred to a prominent member of a group of healers. Early modern physicians still sometimes used the term "Archiater" in this sense, thus giving a kind of honorary title to the leading local doctor. Even in the late Middle Ages, however, many who were honored with the title of an "Arzt" had not studied medicine. A barber-surgeon or surgeon trained in medicine as a craft, for


The success rate of outsourcing in South Africa is fairly low. Companies that make the incorrect decision to outsource maintenance place themselves at risk of poor maintenance performance, a high operational cost of maintenance, and substantial costs to redevelop internal maintenance capabilities. The identification of the factors applicable to the decision to outsource maintenance can form the basis of a decision framework or model, and has the potential to improve the quality of decision-making in maintenance management. This paper discusses the results of a survey that was carried out to determine the main decision factors that maintenance and asset managers could use when they consider outsourcing some maintenance work. Most of the 62 respondents were from the oil and energy sector or the chemicals sector of South African industry. The main decision factors were identified as contractor experience, the availability of a suitable contractor, and the scarcity of skills or employees. The findings of this survey are useful for maintenance and asset managers to decide whether or not to outsource an activity, and to rank potential contractors.


Homesickness is an important topic in the poems of Lei Pinyang.The homesickness consists of three aspects.Firstly,he is sentimentally attached to Yunnan and his hometown;additionally,his homesickness comes from the urban modernization,and it makes him love and miss the past very much;finally,he makes it be an unique symbol of his poems.


Providing an indispensable resource for undergraduate students, graduate students, and policymakers interested in the prescription drug abuse crisis in the United States, this book summarizes the current state of prescription drug abuse and its growth over the past 20 years.
 The Prescription Drug Problem analyzes the growth of the prescription drug abuse problem from 1994 to 2014 and includes comparisons to marijuana and hard drug use during the same period. Specific attention is given to prescription opiate abuse and the transition from prescription opiates to heroin.
 The book begins with a broad overview of the prescription drug problem in the U.S., while the text presents stories of celebrities who have struggled with prescription drug abuse, highlights a handful of ordinary Americans who are battling prescription drug abuse, and examines as case studies a few communities that have been ravaged by prescription drug abuse. Drawing upon demographic patterns of abuse to identify causes of and factors contributing to prescription drug abuse as well as possible solutions to the problem, the book is designed to provide a broad overview of the prescription drug abuse problem in the U.S. and stimulate additional research.


In my early years of general practice I was enthusiastic about controlling blood pressure. One particular patient, a retired civil servant, presented with a sore throat, and an incidental finding showed a blood pressure of 200/130.

I was not sure how much of this was caused by meeting a new doctor so I took his blood pressure several times and it continued to be high. A general physical examination was unremarkable apart from a soft ejection systolic murmur at the left sternal edge. In particular, he had no protein in his urine and his fundi showed only grade 1 retinopathy. Baseline investigation showed his renal function was normal, mid—stream urine specimen was negative, and serum urate was normal. I initially started him on bendrofluazide at a dose of 5 mg a day, which was …


Aiming at monitor and analysis on batch drilling-quality,an acoustic emission sensor was used to collect the acoustic emission signal,extract statistic characteristics and then construct the signal characteristic vector.An improved incremental density based spatial clustering algorithm of time-domain applications with noise(InDBSCAN) was put forward to analyze the distribution law of batch drilling-quality indirectly.Take new data insertion into consideration.Because some of the original clusters could be remerged when the new cluster was created,and so the InDBSCAN algorithm was modified.The results show that the conclusion of incremental cluster analysis is more reasonable by the improved InDBSCAN algorithm and the detection accuracy of batch drilling-quality is up to 84.3%.


This study presents the design of a three-phase slotless brushless DC (BLDC) motor for use as an electromagnetic actuator in robotics. To achieve the high torque-to-inertia and torque-to-weight ratios required for fast response in robotic applications, genetic algorithms (GAs) are used to optimise the initial motor design within a reasonable geometry. We examine the machine performance using 3-D finite element analysis (FEA) and validate them by experimental measurement.


The born of ten plus three framework offers the cooperation in the Northeast Asia systematic guarantees, and the cooperation among China, Japan and South Korea in the Northeast Asia became the key factor of the regional cooperation. At the present, the major obstacle of the cooperation among China, Japan and South Korea is the lack of mutual trust between China and Japan. The two countries should draw lessons from the past and to face the future , to promote the cooperation in the Northeast together. The openness should be the sustainable element in Northeast cooperation, take the framework of ten plus 3 as the main approach, and go ahead with multi-ways.


Recombinant cognition synthesis (RCS) provides an architectural framework and methodology for combining multi-source metadata with predictive and analytic algorithms to synthesize actionable knowledge. RCS bridges an implementation gap in the current Joint Directors of Laboratories (JDL) data fusion model by specifically addressing the integration of fusion levels 2 to 4. The situation awareness (SA) envelope is predicated on a three-dimensional vector space, which comprises spatial, temporal, and semantic attributes of multi-source object metadata. The threat assessment (TA) envelope is defined by the vector space, which comprises means, motive, and opportunity weighted coefficients. Machine learning algorithms, statistical analysis, and predictive data mining techniques are applied to recombined metadata fused across its trans-dimensional attributes. An extension to the ISO 19115 model captures the necessary metadata for this fusion framework, and additionally provides the qualitative and probabilistic attributes to enable process refinement (PR).


[Objective] To observe the expression of glutamate in trigeminocervical complex and trigeminal ganglion of rat following GTN infusion,and to speculate the levels of NR2B,phospho-NR2B protein expression in cell membrane of rat trigeminocervical complex for the investigation of relationships between Glu-NR pathway and the central hypersensitivity evoked by Glyceryl trinitrate infusion in rats.[Methods]Rat migraine model was established with GTN 2 μg·(kg·min)-1 infusion for 30 min.Immunohistochemical staining was used to observe the expression of glutamate in trigeminocervical complex,and in trigeminal ganglion of rat following GTN infusion.The levels of NR2B and phospho-NR2B protein expression in cell membrane of rat trigeminocervical complex were detected following GTN infusion by Western-blot.[Results]The glutamate increased in rat trigeminocervical complex while decreased in trigeminal ganglion.The level of NR2B protein expression remained the same after GTN infusion.The increase of phospho-NR2B protein expression in rat trigeminocervical complex was detected after GTN infusion.[Conclusions]These results demonstrate that the involvement of Glu-NMDAR pathway mediated mechanisms in central hypersensitivity evoked by glyceryl trinitrate infusion in rats.


Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary vascular resistance that leads to right ventricular failure. PAH can be a primary disease (idiopathic, IPAH) or secondary to conditions such as connective tissue disease. Interleukin‐33 (IL‐33), which is the ligand for the ST2 receptor, is a cytokine that acts as an alarmin. Since PAH is associated with the infiltration of inflammatory cells and increased cytokines, we aimed to investigate the role of IL‐33 in PAH. Using an IL‐33 ELISA we found that IL‐33 is increased in the serum of PAH patients, in particular IPAH [1798 +/‐846 pg/ml (n=6) vs. 24 +/‐ 13 pg/ml (n=6), p<0.01], compared to control subjects. We found that the mRNA expression of IL‐33 is increased ~8‐fold in peripheral blood mononuclear cells isolated from PAH‐patients and PAH‐animal models compared to control; Il‐33 is up‐regulated in the lung of animal models of PAH. Injury of pulmonary artery endothelial cells (PAEC) released IL‐33, thus implying that the increased circulating IL‐33 with PAH may occur if the membrane integrity of PAEC is compromised. Administration of IL‐33 (500 ng/day intracheally for four days) induced pulmonary arterial remodeling in WT and IL‐33 KO mice, but not ST2 KO mice. Our data demonstrate that IL‐33 is increased in PAH, which via ST2‐dependent signaling, contributes to remodeling of the PA and hence the pathophysiology of the disease.


This paper in detail introduced the realization plan, the composition structure and the characteristic of multi-channel signal gathering system. The entire gathering system completes to 13 group input signal sampling, The AD transformation precision is 12bit, and each group signal sampling frequency is not lower than 12.5 kHz. This system including the analog switch, surveys the amplifier, the AD sampling instrument, CPLD central of logic controller and power failure data preservation unit. Simultaneously, the system also has with the computer asynchronous serial communication interface based on the programmable logic device CPLD.


We propose a new approach to portfolio optimization by separating asset return distributions into positive and negative half-spaces. The approach minimizes a newly-defined Partitioned Value-at-Risk (PVaR) risk measure by using half-space statistical information. Using simulated data, the PVaR approach always generates better risk-return tradeoffs in the optimal portfolios when compared to traditional Markowitz mean–variance approach. When using real financial data, our approach also outperforms the Markowitz approach in the risk-return tradeoff. Given that the PVaR measure is also a robust risk measure, our new approach can be very useful for optimal portfolio allocations when asset return distributions are asymmetrical.


The construction of social morality can't be divorced from specific historical environment.Originated from Zhou and Qin Dynasties,the Chinese traditional morality is based on kin relation,centered on family ethics,aiming to strengthen autocracy,and preconditioned on snuffing human nature.Modern Chinese morality should be based on democracy,science and emancipation of personality,centering on professional ethics,commercial ethics,and social morality.After criticism and scrutiny,old morality can be utilized today,but it can never be copied.Recovering old morality is Absolutely unrealistic.


In order to save storage space and improve transport efficiency from huge of dynamic data of TTC ship-borne trajectory measurement equipment,the ship-borne central computer must reprocess and compress the data.An algorithm based on polynomial fitting for real-time trajectory data compression is proposed in this paper.A series of orthogonal polynomial basis are presented and the smoother formula of output point with the least square filtering is applied.When the truncation error and random error are considered simultaneously,the best filter is obtained.Computational results show the novel algorithm is a promised compression and noise filtering method.


Background: Nasal Highflow has a growing importance in clinical practice. Unfortunately there exist only few small studies. Effectiveness and mode of action of this new non-invasive ventilatory support device is unclear.

Aims: We want to prove the hypothesis that Nasal Highflow works through a wash-out effect.

Methods: We used a self-constructed lung model. CO2 was introduced in the "lung" and measured continuously. We ventilated the "lung" with a tidal volume of 400 ml and a breathing frequency of 20/ min. After achievement of stable CO2 values we added NHF with 20 l/ min.

Results: The concentration of CO2 decreased of 7,7 %Vol by application of 20 l/ min.

Discussion: Increasing flow results in a wash-out of CO2 in a lung model. This result shows a good correlation with blood gas measurements in patients with COPD (pCO2 -9,9%) and IPF (-6,1%). This observation supports the hypothesis of a wash-out effect of NHF as main mechanism.


1. Single‐ and double‐tracer experiments were performed in cats to investigate the relationship between the aortic cells and the cell bodies accumulating 5‐hydroxytryptamine (5‐HT) in the nodose ganglion. In one series of experiments, horseradish peroxidase (HRP) was applied to the central end of the aortic nerve, anterogradely transported and accumulated in ganglionar perikarya. The distribution of HRP‐positive neurones was reconstructed in serial sections through the nodose ganglion. In a second series of experiments, the distribution of [3H]5‐HT‐accumulating cell bodies was assessed following incubation of the nodose ganglion in [3H]5‐HT. The third series of experiments combined the treatments of the preceding ones: anterograde transport of HRP in the aortic nerve followed by incubation of the nodose ganglion in [3H]5‐HT.


Purpose The number of infrapopliteal runoff vessels seems to be one of the factors influencing arterial patency in patients who had undergone superficial femoral artery (SFA) angioplasty with stenting. However, the effectiveness of infrapopliteal runoff vessels in predicting patency during SFA angioplasty remains unclear. This study aimed to determine whether the number and quality of infrapopliteal runoff vessels affect the primary patency after SFA angioplasty with stenting in patients with claudication. Methods Materials and This study reviewed a retrospective database of patients with claudication who underwent SFA angioplasty with stenting between March 2011 and December 2016. The preoperative computed tomography findings of all patients were reviewed to assess infrapopliteal runoff vessels. The Trans-Atlantic Inter-Society (TASC) II classification and modified Society for Vascular Surgery (SVS) runoff score were used for subsequent analysis. Kaplan–Meier survival curves were constructed, and Fisher's exact and chi-square tests were used for data analysis. Results A total of 153 limbs of 122 patients (88.2% male, mean age: 69.1 years) underwent SFA angioplasty with stenting. The overall primary patency rates of TASC II A/B and C/D cases were 77.1% and 31.2%, respectively, at 36 months (P<0.001). The primary patency rates at 36 months using the modified SVS runoff scoring system were 64.6% and 49.8% for the good-to-compromised (≤9 points) and poor (≥10 points) runoff groups, respectively (P=0.011). Conclusion The modified SVS runoff scoring system is effective in predicting primary patency after SFA angioplasty with stenting in patients treated for claudication.


The performance of inherent orifice‐restricted aerostatic bearings (IORABs) is directly determined by the coupling of air flow in the orifice and clearance. This paper presents a novel full‐region model to analyse the performance of IORABs. The air flowing in the orifice is treated to be adiabatic. The air flow in the pressure depression region of the clearance, which is the key factor influencing the bearing performance, including inertial and viscous terms, is modelled. The Reynolds equation is used to simulate the air flow in the laminar flow region of the clearance. By using this model, the pressure distribution, including the pressure depression characteristics, could be accurately predicted and achieved substantial agreement with the experimental results. The predicted load capacity is accorded well with the published experimental data without relying on the discharge coefficients. The airflow characteristics in the orifice are crucial in determining the bearing performance and directly influenced by the orifice inner surface shape (OISS). Therefore, the pressure distribution and the static characteristics of the bearings with coupling different OISS are also systematically analysed by using this model. Narrowing and widening OISS influence the pressure depression region and the pressure value of the turning point to directly influence the static characteristics of the bearings. The full‐region model and the results are significantly for guiding the precisely calculating and designing the IORABs.


We consider the mixed ray transform of tensor fields on a three-dimensional compact simple Riemannian manifold with boundary. We state an elastic travel-time tomography problem for qS-waves and recall how the linearization of this problem in certain anisotropic medium leads to mixed ray transform for $2+2$ tensor fields. We prove the injectivity of the transform, up to natural obstructions, and establish stability estimates for the normal operator on generic three dimensional simple manifold in the case of $1+1$ and $2+2$ tensors fields. These are the first key steps towards solving the anisotropic elastic travel time tomography problem.


Abstract Can the existence of motivationally biased beliefs plausibly be explained without appealing to actions that are aimed at producing or protecting these beliefs? Drawing upon some recent work on everyday hypothesis testing, I argue for an affirmative answer. Some theorists have been too quick to insist that motivated belief must involve, or typically does involve, our trying to bring it about that we acquire or retain the belief, or our trying to make it easier for ourselves to believe a preferred proposition—and too quick to conclude that such exercises of agency are involved in specific instances of the phenomenon. There are alternative ways to accommodate the data, and it is far from clear that the "agency view" accommodates them better.


Abstract The principal assumption underlying the model is that Presidential budget recommendations [only for goods and services] are an adequate approximation to Congressional appropriations. This implies that Federal purchases depend on the past stream of budget recommendations. It is suggested that the time shape of this past stream be represented by Koyck and/or Pascal distributed lags. Our best forecasting system, which combines Koyck and Pascal distributions, results in forecast errors of −2.03 per cent for fiscal 1960 and 1.10 per cent for fiscal 1961. We conclude that a distributed lag in budget recommendations for goods and services is extremely useful for forecasting Federal purchases.


The power performance of a wind turbine depends on several characteristics of the inflow, such as wind speed, turbulence and wind shear. Additionally, wind turbine control strategies affect the power performance of the wind turbines; under certain conditions one might want to, e.g., intentionally misalign the turbine with respect to the main wind direction. Here, we evaluate whether the accuracy in power performance evaluation can be improved by using multi-dimensional power curves in the form of multivariate polynomial regressions, which define the power output as function of wind speed, turbulence and yaw misalignment. The analysis is conducted on a dataset of virtual power performance measurements, which is generated through aeroelastic simulations combined with a simulator of nacelle lidar measurements. Results show that the multi-dimensional power curves can provide higher accuracy than those derived using the IEC standard for power curve measurements; the error in power prediction is nearly halved compared to that using the IEC standard power curve method. Additionally, we show that nacelle lidar measurements increase the accuracy of the multi-dimensional power curves when compared to using mast-based anemometer measurements.


During the oil field waterflooding process, bedding slip will happen if high pressure injection water cuts into the mudstone and shale interlayers, and regional casing impairment will be induced. The influence of seepage field on the stress field includes two aspects: on one hand, pore pressure is assumed as a body force and applied to the rock mass; on the other hand, the hydration of mudstone and shale is obvious, which will decrease rock mechanical properties. Based on the Mohr-Coulomb theory and effective stress principle, the sliding mechanism of interface rock is analyzed, and also the maximum of pore pressure can be given. The three dimension model is built, and contact element is used to simulate the interface between mudstone interlayer and sandstone reservoir. The numerical simulation results show that with the increase of pore pressure, the sliding displacement and the Mises stress of casing has increased. The numerical simulation analysis provides theoretical basis and effective methods of water injection to reduce casing damage during the oil production process.


INSOLUBLE deposits of calcium salts can be demonstrated in tissue sections by methods that are either specific for calcium itself or rely upon the nature of the anions to which the calcium is


A complication has been made from data in the literature to provide the practitioner and research worker with practical guidelines in the nutrition and management of hand-reared puppies. On the basis of neural development and behavioural patterns and metabolic requirements, recommendations are made regarding handling, management and feeding.


In the present paper, the authors discuss the theory of the collateral system of meridians and collateral diseases from ① the pose of the concept of "collateral system and collateral diseases"; ② the component of the collateral system; ③ functions of the collateral system; ④ pathology of the collateral system; and ⑤ clinical application of the theory of the collateral system and collateral disorders. The collateral system is composed of fifteen major collaterals, yin and yang collaterals, minute collaterals, superficial collaterals, etc. and is the basic functional unit for transporting qi and blood, communicating the zangfu organs and the body surface, and regulating physiological activities of the human body. The collateral diseases are those functional disorders of the body caused by various factors induced blockage of the collateral branches of meridians and dysfunctions of circulation of qi, blood and body fluid. The deep research on the theory of the collateral system and collateral diseases will help us a lot in carrying forward and developing traditional theories of Chinese medicine, gaining a clear idea about the essence of the doctrines of zangfu organs and meridian collaterals, understanding the pathogenesis of different diseases, and in making correct diagnosis and treatment of various disorders according to the comprehensive analysis on the symptoms and signs.


In the current epidemic, the whole world is suffering with the infectious disease i.e., Corona Virus Disease (COVID-19). It is important to wear a mask to minimize the transmission of the disease. When everyone is wearing a face mask, it is difficult for recognition systems to recognize the masked face of a specific person. As some of the facial features are covered behind the mask e.g., mouth and nose. Therefore, the face-recognizing systems are inefficient to recognize the masked faces. To solve this issue, a face recognition system is proposed to recognize masked and unmasked faces. Support vector machine (SVM) and Random Forest (RF) based classifiers are trained on the specific dataset and classifiers effectively recognize the masked and unmasked faces. The classifier recognizes the human facial features such as eyes, eyebrows, forehead, ears, and hair. The dataset is collected in the form of images for 28 classes with and without a face mask. The trained system will recognize the person, whether the person is wearing a mask or not. The recognition accuracy is approximately 98.2% for different classes and the proposed recognizer is also compared with the state of art existing techniques.


Masni: The Effect of Leadership Style, Reward and Punishment on Work Motivation at PT. Karyanusa Eka Daya, East Kutai Regency. (under the guidance of Advisory Lecturer I Mr. Suyanto and Supervisor II Mrs. Meinard Maya Safitri)
The importance of employees who cover the role of utilization and management of employees is needed to grow the work ethic of employees, the company must comply with a number of requirements by applying effective HR management techniques and concepts, namely from how someone leads, rewards and punishments. The effectiveness of achieving the company's vision is strongly influenced by the role of the leader. A leader must be able to influence and direct appropriately so that employees are willing to carry out their work without coercion and are happy to work together to realize company goals.
The research objective to be achieved is to find out and analyze whether the Leadership Style, Reward and Punishment have a partial or simultaneous effect on Work Motivation on Employees of PT. Karyanusa EkaDaya, East Kutai Regency.
Based on the research, the results obtained partially that the leadership style variable has no significant positive effect on work motivation at PT. Karyanusa Eka Daya, East Kutai Regency. Partially, the reward variable has a significant positive effect on work motivation at PT. Karyanusa Eka Daya, East Kutai Regency. Partially, the punishment variable has no significant negative effect on work motivation at PT. Karyanusa Eka Daya, East Kutai Regency. Simultaneously the variables of leadership style, reward, punishment have a significant positive effect on work motivation at PT. Karyanusa Eka Daya, East Kutai Regency.

Keywords: Leadership Style, Reward, Punishment and Work Motivation


pollution of the region was mainly the result of military activity. For the moment this proposal has only received the support of the Vatican. In 1980 the idea emerged once again in a Canadian research report which advocated making the Arctic Ocean a denuclearised area. In the opinion of the advocate of this proposal, the strategic significance of these waters was still somewhat uncertain. For this reason, the


exchanger of the evaporator type for refrigerant comprising a tube bundle of which the tubes open into a honeycomb distribution plate distributing the refrigerant in independent tubes or independent sets of tubes, characterized in that the distributor plate 5 is covered by a plate dispatcher 11 to which is connected a feed pipe 12 of the refrigerant, the dispatcher 11 plate having at least one series of calibrated conduits 14 for uniform distribution of the refrigerant in the alveoli distributors 6 different tubes or tube sets 1. (CF DRAWING IN BOPI)


Summary: The specific airway resistance (SRaw) is a relatively precise parameter of bronchial quality and in normal children its relation with body length, although very significant (P < 0.001), is so poor that it can safely be disregarded (Fig. 4). Also the dispersion around the mean value remains stable at any body size (Fig. 4). Contrasting with the inverse relation between airway resistance (Raw) and lung volume, SRaw does not show any systematic variation with lung filling (Fig. 5). These data are consistent with the new formulas: SRaw = tg β; (PB – PH2O) and Raw = SRaw/TGV in which tg β; stands for the relation between the plethysmographic box volume and breathing flow fluctuations (Fig. 2); PB – PH2O represents the ambient pressure corrected for water vapor pressure at body temperature; TGV is the thoracic gas volume at mean expiratory level. In disease SRaw varies more rapidly and markedly with any alteration of the airways than does Raw (Fig. 6). Consequently, a normal value for SRaw would indicate that both Raw and TGV must be in a normal range.Speculation: For those who operate with a whole body plethysmograph the authors purpose to use specific airway resistance more frequently for the study of lung mechanics in children. It is a reliable parameter which can be measured very quickly and this should enhance knowledge about the mechanism of many lung diseases in pediatrics.


The quality of public urban transit organization depends to a great extent also on the organization and the quality of on-trip and pre-trip information services. The aim of this service is to provide relevant, accurate and usable traffic and transport information to current users of the public urban transit, as well as to attract new users, alleviating the burden on the roads and insuring high-quality transport service to motorists who at least on one section of their trip use public transport means. Apart from classical information forms this system greatly relies also on new telecommunication technologies including the third generation of mobile networks and mobile Internet. Apart from the wide range of methods of collecting information, their processing and dissemination, the entire problems of introducing the mentioned services into the newly organized system such as LRT needs to be systemically analyzed. It is especially important to analyze in advance and to define the relations between the private and public sector in the described process. The corporate plans of organizing the system of on-trip and pre-trip information in the LRT system applicable in the City of Zagrebare considered. Their implementability has been evaluated by a professional team defining the relevant factors in the selection of the corporate plan.


The International Association of Independent Tanker Owners (Intertanko) is an organization of tanker owners dedicated to promoting safe transport, clean seas, and free competition to ensure that oil is shipped safely, responsibly, and competitively. The precursor to Intertanko was spawned during the 1930s depression. Intertanko membership is offered to independent tanker owners who own or commercially manage crude oil, product, chemical, liquid gas carriers, and vessels used in offshore oil exploration and production. Intertanko holds meetings during spring and autumn when the Council of Intertanko is elected. The Council of Intertanko is responsible for establishing policy while the Executive Committee is responsible for implementing policy as well as supervising the management of the permanent secretariat. Intertanko finances itself primarily through membership fees. Intertanko's role in transnational economic governance is accomplished through the efforts of working committees such as Bunker-Sub Committee, Chemical Tanker Committee and Communications and Public Relations Committee. Keywords: Chemical Tanker Committee; International Association of Independent Tanker Owners (Intertanko); membership fees; transnational economic governance


Proton precession magnetometer (PPM) is a potential device to measure the low-frequency geomagnetic field in the time domain. Nevertheless, the uncontrollable noise such as power frequency noise, random noise, etc., severely affects the detection results. In this paper, aimed to boost the performance of the PPM, a novel real-time processing algorithm for the optimization of PPM output strategy based on the low-rank constraint (LRC) is proposed, and a new efficient framework, dubbed LRC-based geomagnetic data readout optimizer (LRC-GDRO), is implemented. This method aims to extract the dominant principal components of the pure magnetic signal and identify the singular values of noise. Thereby, the relative ideal signal without external noise, which still contains the ambient field information is yielded. Moreover, we develop a prototype device and compare the test results before and after using the proposed method. Consequently, compared with traditional PPM, the performance of the PPM using the proposed method has been significantly improved with a measurement accuracy of ± 0.2 nT. Furthermore, the experimental results reveal that the LRC-optimized PPM is comparable to a very high-accuracy Overhauser magnetometer in terms of 12 h geomagnetic field observation.


Magnesium doped potassium lithium niobate single crystal (K 3 Li 2 Nb 5 O 15 :Mg, denoted as KLN:Mg) has been grown by modified Czochralski technique. It has tetragonal tungsten bronze type structure. At room temperature, the point group is 4 mm with the lattice constants a = 1.262 nm and c = 0.398 nm. Dielectric, pyroelectric properties of a and c plates were studied in the temperature range from 10 to 700 K. The frequency dependence of dielectric constant in the frequency range 5 × 10 2 to 5 × 10 8 Hz was measured. Results reveal a paraelectric-ferroelectric phase transition near 623 K and a ferroelectric-ferroelectric phase transition near 80 K.


Six RC short-limb shear walls with an L-shaped section, constructed with high-strength rebar and high-strength concrete, were loaded to destruction with pseudo-static loading. Experimental results were discussed and compared with L-shaped RC short-limb shear walls with high-strength horizontal rebar in detail. Different failure modes were obtained, such as flexure-dominated failure for specimens with an aspect ratio of 2.8 and 2.15 and bending-shear failure for specimens with an aspect ratio of 1.75. With a decrease in the aspect ratio, ductility decreased, whereas with an increase in the axial compression ratio, the load-carrying capacity increased but ductility decreased accordingly. An obvious pinching effect was found in specimens with a smaller aspect ratio and a higher axial compression ratio. Using high-strength longitudinal rebar and high-strength concrete can obviously improve the lateral load-carrying capacity of walls; and using high-strength horizontal rebar can obviously improve the ultimate deformation capacity. The average ultimate drift ratios of HPLW and LW far exceeded the specification requirements of the Chinese GB50011-2010 code.


The pest insect control with organosynthetic pesticides provoke many problems; for this reason, many alternatives have been implemented. However, these ones have not been included to reach a better management. This research was conducted to evaluate the effect of the mineral fertilization or organic without fertilizing it, conventional soil or organic and with or without agronosodes homeopathic in the development of the bean´s shell and also the foliage damage of the old one.To this effect, bean was planted with these treatments and it was offered as plant or cut leaf to ten maggots of first instar in two experiments. The different parameters in the insect biology and the daily foliage damage of the old one were evaluated. The compost at one and three tons ha-1, and the organic soil, independently, reduce from 7 to 14.6% the larval duration regards to the mineral fertilization and to the conventional soil and doses of 1.8 to 3.6 t ha-1 and the agronosode at 200CH reduce in 50% or more the adult foliage damage, but combined lose the effect. The organic combine soil with agronosode at 200CH reduces in 85.7% the pupal viability. The organic soil integration with compost 3 t ha-1 of compost or with agronosode at 200CH prejudices the insect and protects the crop.Produccion Agropecuaria y Desarrollo Sostenible, Vol. 6, 2017: 43-56


10016 Background: Adjuvant targeted therapy (TT) improves relapse free survival (RFS) in patients (pts) with BRAF mutant stage 3 melanoma. The outcomes and optimal management of pts who relapse after adjuvant TT is unknown. Methods: Pts from 21 centres with recurrent melanoma after adjuvant TT were included. Disease characteristics, adjuvant therapy, recurrence, treatment at relapse and outcomes were examined. Results: 87 pts developed recurrent melanoma; 21 (24%) during and 66 (76%) after cessation of adjuvant TT. Median time to 1st recurrence was 16.3 months with median follow up after 1st recurrence of 31 months. 30 (34%) pts recurred locoregionally, 51 (59%) pts developed distant recurrence and 6 (7%) pts had both. Of those who recurred locoregionally, 23/30 (77%) pts underwent surgery to no evidence of disease, only 3 (13%) of which received adjuvant anti-PD1 therapy, and 15/30 (50%) subsequently developed distant disease. 29 (33.3%) pts have died. 75 (86%) pts received systemic therapy at either 1st or subsequent recurrence. 40 (46%) pts received 1st line anti-PD1 based therapy (single agent anti-PD1, anti-PD1 with ipilimumab or anti-PD1 with investigational agent), 12 (14%) pts received ipilimumab monotherapy, 18 (21%) pts received retreatment with combination BRAF/MEK inhibitors and 5 (6%) pts received other agents (chemotherapy, TVEC). 57 (66%) pts had disease that was assessable for response rate (RR). RR after relapse was 69.7% (23/33) to 1st line anti-PD-1 based therapy, 46% (6/13) to TT and 9% (1/11) to ipilimumab monotherapy (Table). Median overall survival (OS) from date of 1st recurrence for all pts was not reached. OS varied by drug class received as 1st line systemic therapy after relapse. 3 year OS was 79% for anti-PD-1 based therapy, 55% for TT and 25% for ipilimumab. Conclusions: This study demonstrates that pts who relapse after adjuvant TT may respond to subsequent immunotherapy at similar rates to the treatment naïve setting. [Table: see text]


The production of new fortified feed supplements and concentrates, balanced by the organic nutrients content, takes one of the leading positions in agriculture manufacture. Food production waste has recently been one of the forms of an accessible source of biologically active substances (oilcake, oil meal, molasses, treacle, etc.). Proper processing of these raw products allows you to use it in obtaining highly nutritious feed supplements with a high content of protein, minerals, vitamins, and sugars. Food waste does not harm the animal's body; it was found; they have easily processed and high biological value. This work is presents the formulation of a new extruded feed supplement, using it in the main ration of lactation cows increases the productivity of the animal by 10-12%. The mass protein fraction in the obtained milk was in 9-11% higher comparative to milk from cows without receiving an additional feed supplement in their rations. It is proved that the developed extruded feed supplement does not adversely affect the body of lactation cows, which is confirmed by a research of the morphological blood composition.A supplementation dairy cow with 3 kg per cow daily for 15 days of our studded concentrated mixture is recommended.


An improved integral method is proposed and developed
for the quantitative prediction of distorted inlet flow
propagation through axial compressor. The novel integral method is
formulated using more appropriate and practical airfoil
characteristics, with less assumptions needed for
derivation. The results indicate that the original integral method
(Kim et al., 1996) underestimated the propagation of inlet flow
distortion. The effects of inlet flow parameters on the
propagation of inlet distortions as well as on the compressor
performance and characteristic are simulated and analyzed. From
the viewpoint of compressor efficiency, the propagation of inlet
flow distortion is further described using a compressor critical
performance and its associated critical characteristic. The
results present a realistic physical insight to an axial-flow
compressor behavior with a propagation of inlet distortion.


46 47 This study was conducted to evaluate the relationships and correlations between the 48 structural characteristics of Brachiaria decumbens cv. Basilisk in places the same 49 pasture with grazing intensities variables. Due to the inherent spatial variability of 50 ENCICLOPEDIA BIOSFERA, Centro Cientifico Conhecer Goiânia, vol.6, n.9, 2010 Pag.1 vegetation, three sites of the same pasture were evaluated: overgrazed, undergrazed 51 and with adequate grazing. A randomized block design with three replications was 52 used. The continuous stocking method with a variable stocking rate was adopted to 53 maintain the average height of pasture at 25 cm. Linearly, the density of live tillers 54 decreased and the vegetative tiller weight increased with increasing herbage mass at 55 the sites of the same pasture signalgrass. The height of the pasture and extended 56 plant height showed negative correlations with the number of vegetative tillers, but 57 positive with the number of reproductive tillers. The correlation of index damping was 58 positive to the number of reproductive tillers (0.55) and negative (-0.88) with the 59 number of dead tillers. The weight of live tillers and herbage mass are related in a 60 positive way in the same local pasture B. decumbens cv. Basilisk with varying levels 61 of grazing. On the other hand, there is tradeoff between the number of vegetative 62 tillers and herbage mass at the sites of the same pasture B. decumbens cv. Basilisk 63 with varying levels of grazing. Inferences about the population density of tiller 64 categories based on sward height, plant height and extended the index of registration 65 are possible. 66 67


This article investigates rural differentiation through an inquiry into the ratio of rural housing price to the income of rural households. The households surveyed here are classified into five income groups, namely, the low-income, the lower-middle-income, the middle-income, the upper-middle-income, and the high-income groups. They are further grouped into three categories according to their house-building or -purchasing abilities, namely those whose family members mainly live in the purchased condominiums in towns and cities; those who live in the newly built houses in the countryside; and those who give up building a new house in the rural area. It is concluded that income gap is the root cause of rural stratification, that the well-to-do of the rural households tend to flow into the towns and cities, which impedes the long-term development of the rural area and the entire national economy, and that those households who give up a house-building plan have basically lost their upward-moving opportunities in the course of social restructuring. (This article is in Chinese.) 摘要运用农村房价收入比指标推断农村人口分化,计算农村低收入、中等偏下收入、中等收入、中等偏上收入和高收入5个收入组的房价收入比,依据建房能力和实际建房的完成时间将农民分成主要家庭成员在城镇购房居住人口、在农村建新房居住人口、放弃在农村建新房居住人口3个群体。得出结论:农村人口分化的根本原因是收入的分化;3个阶层的选择体现出农村中以"小"为中心的文化氛围;优质资源单向由农村流向城镇,造成恶性循环,不利于农村和全国整体经济的长久发展;放弃建房人口在住房分化中向上通道基本闭塞。


Section I: Educational Psychology and Measurement. L.B. Resnick, Giving Psychology Away: From Individual Learning to Learning Organizations. E. Ribes-Inesta, Which Should be the Contribution of Psychology to Education? A. Orantes, Activating Historical and Conceptual Links in the Realm of Instruction in Latin America. Q. Dong, S. Tao, B. Li, W. Wang, C. Chen, English Classes without English Teachers: The Pan Deng English Learning Program. J.P. Das, Rules and Tools of Intelligence: How IQ Became Obsolete. F.M. Cheung, A Combined Emic-etic Approach to Cross-Cultural Personality Test Development: The Case of the CPAI. D. Wang, H. Cui, Chinese Personality: Structure and Measurement. Section II: Health Psychology. C.D. Spielberger, Effects of Stress, Emotion, and Type-A Behavior on Heart Disease and Psychological Disorders. J. Strelau, M. Kaczmarek, B. Zawadzki, Temperament as Predictor of Maladaptive Behavior under Extreme Stress: The Polish Studies of Natural Disasters. W. Lin, The Involvement of Psychological Processes in Immunocompetence. R. Schwarzer, U. Scholz, S. Lippke, F. Sniehotta, J. Ziegelmann, Self-regulatory Processes in Health Behavior Change. N. Felipe Russo, Violence Against Women: A Global Health Issue. R.D. Fowler, Professional Psychology Around the World: A Fifty Year Progress Report. Section III: Social and Cultural Psychology. R.E. Nisbett, Cognition and Perception: East and West. J.B. Berry, Cross-cultural Psychology: An Ecocultural Approach. M.H. Bornstein, Some Metatheoretical Issues in Culture, Parenting and Developmental Science. R. Singh, Dealing with Norm and Metanorm Violators: Cultural Differences in Thoughts or Motivated Actions? F.J. R. van de Vijver, Culture and Psychology: A SWOT Analysis of Cross-cultural Psychology. H. Kawai, Mind and Body in Japanese Culture. H. Azuma, The Era of Fluid Culture: Conceptual Implications for Cultural Psychology. S. Yamaguchi, C. Lin, S. Aoki, Self-esteem in Cultural Contexts: A Case of Japanese. U. Kim, Y. Park, Understanding Human Potential, Creativity and Achievement: Indigenous, Cultural and Psychological Perspectives. Section IV: Organizational, Applied, and International Psychology. L. Mann, Investigating Five Leadership Themes: Roles, Decisions, Character, Relationships, and Journeys. Z. Wang, Leadership Competency and Implicit Assessment Modeling. D. Gopher, Control Processes in the Formation of Task Units. D.F. Halpern, States of Mind: Political Systems as Implicit Theories of Psychology. V. A. Barabanschikov, Russian Psychology at the Cross Roads. H. Carpintero, Toward a History of Applied Psychology in the 20th Century.


The failure of material always involves with the plastic deformation and fracturing process. For the plastic deformation, the continuum plastic mechanics can competently deal with the plastic deformation through a yield function and the flow rule. However, the continuum mechanics method has some limitations in dealing with the fracture problem due to that it cannot account for the microstructure of the material. The lattice model can simulate the fracture problem very well, but it is inadequate in dealing with plastic deformation. To unify the plasticity and the fracture together on the bond level, the present paper employed the Stillinger-Weber potential-based discretized virtual internal bond (SW-DVIB) method. DVIB is a kind of lattice model. It considers material to consist of bond cells. Each bond cell can take any geometry with any number of bonds. In original DVIB, the interaction between particles in a cell is characterised by an interatomical bond potential, which intrinsically contains the microfracture mechanism. However, because the interatomical potential only accounts for the effect of the bond stretch, the Poisson ratio it represents is fixed. To remedy this drawback, in the SW-DVIB the SW-potential is adopted to characterise the energy of a bond cell. Due to that, the SW-potential can simultaneously account for the bond angle and stretch effect; the SW-potential can represent the variable Poisson ratio. In this paper, the SW-DVIB is adopted to model the elastoplastic fracture. The plasticity is considered in the two-body potential. That is before the bond reaches its yielding point, this bond is linear elastic. After it reaches the yielding point, the bond enters the ideal plastic state. The irreversible deformation is reflected by following different loading-unloading paths. The bond does not rupture until its deformation reaches the limit value, which is related to the bond cell size and the macro fracture energy of the material. The three-body potential is kept linear elastic until the normal bond is ruptured. By this method, several examples were simulated. It is suggested that the irreversibility feature of the plastic deformation can be well captured. It can simulate the fracture propagation of material with the conservation of the fracture energy. The present paper provides an efficient approach to the elastoplastic fracture simulation.


Disclosure, as defined for the purposes of this study, is thesharing with a third party of specific information about anoffender managed under the Multi-Agency Public Protec-tion Arrangements (MAPPA), for the purpose of protectingthe public. Disclosure, for example to an employer, a newpartner or the parent of a child in contact with an offender,may reduce access to potential victims, preventing furthercrimes occurring or resulting in the detection of suchcrimes. Disclosure may also result in social exclusion of theoffender, however, aggravating risk by removing access toprotective factors such as relationships or employment.


Students born in a digital era require adjusted teaching and learning methodologies incorporating new technologies. A common difficulty found by students is how to test their controller designs in a real system. Thus, the development of affordable, portable and easy to use feedback control kits is highly desirable. The idea is that both lecturers and students can perform simple practical experiments anytime and anywhere. The APMonitor temperature control lab is an Arduino based control kit which fulfils these requirements. Proportional, integrative and derivative control is in operation in the vast majority of industrial process control loops. Thus, it is a mandatory topic in most undergraduate introductory feedback control courses. A teaching/learning PID control experiment for undergraduate Biomedical Engineering student's based on the temperature control lab is reported here. Results received from students are presented.


The aim of this paper is to discuss the causes and consequences of the flooding of New Orleans when hurricane Katrina struck the city on 2005 August 29. New Orleans' site is likely to be flooded during hurricanes, but its vulnerability resulted entirely from unwise urban development. Despite very strong natural constraints, urbanized areas spread into former wetlands between 1945 and 2005. The catastrophe resulted in the displacement of 1.2 million people and extensive damage in Orleans and St Bernard Parish drove thousands of 'environmental refugees' out of New Orleans for months.


The field of wearable technology has undergone significant growth in the last few years. Along with this growth come trends in consumer application development, which may be indicative of structural influences on the design and development of products as well as social influences among consumers. Here, we present a two-phase survey of the application space of wearable technology, by assessing applications observed in research or industrial activities from two time periods: initially with a historical focus (mapping the space up to 2014) and subsequently through a 1-year snapshot by mapping developments between 2014 and 2015. We evaluate distribution in application instances over the body surface, over a range of product types, and within a set of application categories, as well as differences in product price and gender target. The implications of changes in product focus areas over these two time frames are discussed.


There were many promising superconducting materials discovered in the last decades that can significantly increase the efficiency of large power transformers. However, these large machines are generally custom-made and tailored to the given application. During the design process the most economical design should be selected from thousands of applicable solutions in a short design period. Due to the nonlinearity of the task, the cost-optimal transformer design, which has the smallest costs during the transformers' planned lifetime, is usually not the design with the highest efficiency. Due to the topic's importance, many simplified transformer models were published in the literature to resolve this problem. However, only a few papers considered this preliminary design optimization problem in the case of superconducting transformers and none of them made a comparison with a validated conventional transformer optimization model. This paper proposes a novel FEM-based two-winding transformer model, which can be used to calculate the main dimension of conventional and superconducting transformer designs. The models are stored in a unified JSON-file format, which can be easily integrated into an evolutionary or genetic algorithm-based optimization. The paper shows the used methods and their accuracy on conventional 10 MVA and superconducting 1.2 MVA transformer designs. Moreover, a simple cost optimization with the 10 MVA transformer was performed for two realistic economic scenarios. The results show that in some cases the cheaper, but less efficient, transformer can be the more economic.


The fact that the people are their own masters is shown by democracy.Voting is the embodiment of democratic centralism,direct and indirect democracy,consultative democracy and self-governing.Voting includes secret ballot and public ballot.Voting is gradually passing from public to secret.But those rights that can be "quantified" can be voted by using registered ballot.An economic democratic system is established in Fushan Industrial Cooperation of Qingdao City.


We propose , an extension of circumscription by allowing propositional combinations and nesting of circumscriptive theories. As shown, Lifschitz's nested abnormality theories (NATs, introduced in AIJ, 1995) are naturally embedded into this language. We analyze the complexity of and NATs, and in particular the effect of nesting. The latter is found a source of complexity, as both formalisms are proved to be PSPACE-complete. We identify cases of lower complexity, including a tractable case. Our results give insight into the "cost" of using resp. NATs as a host language for expressing other formalisms, such as narratives.


Management of lakes for the protection of water quality, aquatic life and other uses must be approached somewhat differently in the tropics from how it is approached at temperate latitudes. More than half of all tropical lakes are accounted for by natural river lakes or reservoirs. Therefore, degradation of water quality in rivers will have direct negative effects on the majority of lakes in the tropics. Also, regulation of rivers, which is one result of river impoundment, is a potential cause of damage to river lakes. Tropical lakes are more sensitive than temperate lakes to increases in nutrient supply and show higher proportionate changes in water quality and biotic communities in response to eutrophication. Tropical lakes are especially prone to loss of deep-water oxygen, and in order to maintain ecological stasis therefore require more stringent regulation of organic and nutrient loading than temperate lakes. Nutrient containment must be more strongly oriented toward nitrogen, the most probable limiting nutrient in tropical lakes, than has been the case at temperate latitudes. However, phosphorus control is also important. Nitrogen management may be more feasible in the tropics because of high temperature, which is one of the critical conditions for efficient denitrification. Planktonic and benthic communities of the tropics bear a close resemblance, both in composition and diversity, to those of temperate latitudes; there is no parallel to the latitudinal gradient in biodiversity that is characteristic of terrestrial ecosystems. Foci of biodiversity, which require special attention, include the endemic species of ancient lakes and the diverse fish communities of very large rivers. The latter are an especially valuable untapped economic resource, but face severe impairment due to hydrological regulation and pollution of rivers. Effective management programs for tropical lakes will focus on interception of nutrients, protection of aquatic habitats from invasive species, and minimization of hydrological changes in rivers to which lakes are connected. In the absence of protective management, tropical lakes will decline greatly in their utility for water supply, production of commercially useful species, and recreation.


Objective To study the security management methods of puerperants with cesarean section. Methods Ninety six puerperants with cesarean section who were intervened with routine security management from July 2011 to December 2011 were selected as control group,and 96 puerperants who were intervened with detail optimization management mode from January 2012 to June 2012 were selected as observation group, then the incidence of adverse circumstances and survival condition of two groups were compared. Results The incidence of various adverse circumstances of observation group were all lower than those of control group, postpartum WHOQOL-BREF score were all higher than those of control group,all P 0.05,there were all significant differences. Conclusion The detail optimization management mode can effectively decrease the adverse circumstances rate of puerperants with cesarean section, so it ensures the operation safety.


A touch electrode device includes a substrate, at least one electrode layer and a conductive ink pattern. The electrode layer is disposed above a surface of the substrate, and the electrode layer includes non-transparent conductive material. The conductive ink pattern is printed on two sides of a surface of the electrode layer.


Abstract Background Tissue precursors of uterine carcinosarcomas remain unknown, therefore targeted therapy has not been determined. Methods This research is based on the investigation of formalin‐fixed, paraffin‐embedded tissue blocks from 17 women undergoing primary surgical treatment between 1961–2010, that were retrieved from the pathoanatomical department of the Institute of Oncology named after N.N.Petrov. In the present study, molecular investigations were applied to determine the pathogenesis of uterine carcinosarcomas. We have analyzed microsatellite instability, mutations of TP53 (exons 5-9), PTEN (exons 5, 8), K-RAS (exon 1) and loss of heterozygosity of variable loci of the chromosome 17 in epithelial and mesenchymal components of uterine carcinosarcomas. DNAs were extracted by proteinase K digestion («Fisher» US) by Herrington, C.S. & McGee, J.O. Mutations of TP53, PTEN and K-RAS were defined by SSCP with the next sequence. Highly sensitive markers BAT 26 and BAT 40 were used for analysis of microsatellite instability. Results The loss of heterozygosity of variable markers of the short arm of the 17th chromosome was detected (in 9 of 17 tumours- 52,9%). All 17 tumours were microsatellite stable. K-ras mutations were detected in 2 of 17 tumours - 11,7%. One tumour contained identical mutations in both components, other one contained mutations only in the epithelial component. Mutations in the TP53 were identified in 13 of 17 tumours - 76,5%. Five (29,4%) tumours contained identical mutations in both components, 8 (47,1%) - only in the epithelial component and 4 showed wild-type TP53. PTEN mutations were detected in 11 of 17 tumours - 64,7%. Six tumours (35,3%) contained wild-type PTEN. Tumours with PTEN mutations showed worse prospects than ones with wild-type PTEN: 1-yr overall survival - 12,5% vs 60 %, р Conclusions Uterine carcinosarcomas are the microsatellite stable tumours. This type of tumours is associated with chromosomal instability of the genome. PTEN mutations are matched with poor prognosis and low overall survival. The present study of PTEN damages may be important for targeted therapy by the PARP inhibitors. Legal entity responsible for the study Russian Medical Academy for Continuous Professional Education. Funding Has not received any funding. Disclosure All authors have declared no conflicts of interest.


The flourishing fame and development of big data in recent years made researchers to have a detailed study. Of the all entire emerging big data research topics, classification of data from big data is identified as a great challenge to address as of our analysis. The Classification is the process of categorizing data for its most effective and efficient use. While analyzing large scale patient records, hierarchical learning approach which is tree structured that train max-margin classifier will give better classification results and also it is computationally efficient. The quality of features has an effect on the performance of hierarchical learning approach for classification of patient records. So we have to extract discriminative features for training hierarchical classifier. In this paper Highly Correlated Feature Set Selection (HCFS) algorithm is proposed to combine with the hierarchical leaning approach to improve its performance. This algorithm identifies the good feature subsets which will improve the classification accuracy.


Throughout 2016 to 2018 there were 29 cases of criminal acts committed by thugs in vital tourism objects in the city of Padang. Thug Handling of Tourism Objects in Padang City By Pam Obvit West Sumatra Regional Police is conducted by conducting raids or inspections by officers of the Padang City tourism area. Constraints in Tackling Thugs in Tourism Objects in Padang City By Pam Obvit West Sumatra Regional Police is a factor in human resources / lack of personnel, lack of community participation / management of attractions. Efforts Made by the Directorate of Safeguarding Vital Objects in Overcoming Barriers to Safeguarding Tourism Objects against Thugs in the City of Padang tourist area is to increase Human Resources or the Number of Police Personnel by empowering the local Bhabinkamtibmas, Increasing community participation / management of tourism objects. Optimizing the Role of West Sumatra Regional Police Obvit Pam in the Thugs Repacking in Tourism Objects in Padang City with collaborative efforts between the police and the community through police synergy where both together identify and solve the occurrence of thug problems.


Harrogate High School students have helped with the smooth running of this year's Crucial Crew at the Ripon Army Barracks. Crucial Crew is an annual ...


A method for coating an implant with soluble in the body calcium phosphates, in which from a calcium-containing and phosphate-containing solution for preparing the coating, an electrolytic deposition takes place on the implant, characterized in that the dispersion particles are incorporated in the coating that dispersing particles of a biocompatible metal salt and / or a plastic and / or a ceramic material are that flaws are in a deposited layer generated which are used for receiving and / or anchoring of dispersion particles, and that the electrolyte is stirred to einzuschwemmen dispersion particles in a layer ,


and difficult to use according to historians' notions of evidence. Speaking with Vampires is an admirable, fascinating work, made with serious intent and honest questioning. It is also frustrating for folklorists because White treats the rumors not as performances, but as historical evidence. Accordingly, she is not interested in individual texts in their specific context but the whole regional genre of vampire stories. She raises issues that no longer interest folklorists as much: How were these rumors disseminated? Why do different versions arise? However, these frustrations pale beside White's achievements: she opens up new territory for African historiography, so concerned with positivism and the purity of oral voices, and speaks to the problems and possibilities of using rumor and belief to apprehend African perspectives on colonialism.


In light of the current problems about Electric Circuit course teaching in universities, the problems in the current teaching of the course are presented and analyzed. The international idea of CDIO is put forward and introduced, and this educational mode is applied in Electric Circuit course teaching. Reform is made to change the current situation that students are weak in experiments and practice links, and concrete measures are proposed. It is shown that this teaching mode can help students not only to promote the understanding and grasp the knowledge points but also it can improve the innovation ability, engineering ability and cooperation ability, communication ability effectively. It will be helpful both to the graduates and society. This teaching mode proposed is effective and feasible.


We comment on the conformal boundary states of the c = 1 free boson theory on a circle which do not preserve the U(1) symmetry. We construct these Virasoro boundary states at a generic radius by a simple asymmetric shift orbifold acting on the fundamental boundary states at the self-dual radius. We further calculate the boundary entropy and find that the Virasoro boundary states at irrational radius have infinite boundary entropy. The corresponding open string description of the asymmetric orbifold is given using the quotient algebra construction. Moreover, we find that the quotient algebra associated with a non-fundamental boundary state contains the noncommutative Weyl algebra.


Objective: Water birth, in which women experience part of the ir labor and delivery in a tub filled with warm water, is a non-invasive method of childbirth. It i s also the most attention-grabbing among all delive ry methods. This study aimed to identify the knowledge levels r egarding giving birth in water among pregnant women , and to determine and increase their awareness on water bir h. Material and Method: The sample of this cross-sectional study consiste d of 1,000 pregnant women in varied phases of their pregnancy who were referred to the Polyclinics of Gynecology and Obstetrics of a unive rsity hospital and a state hospital in Eskisehir. Researc h data were collected using a questionnaire form wh ich was developed through literature review. Data were anal yzed using IBM SPSS (version 20.0) and Minitab (ver sion 16.0) statistical software through descriptive stat i ics, the Chi-square test, the K-Means clustering a alysis and the Roc analysis. P<0.05 was accepted as the signif icance level. Findings: The mean age of the pregnant women who participate d in this study was 26.52±5.17. Of the pregnant women, 39.5% stated that they wanted to give birth in water. After the pregnant women watched the vide o on giving birth in water, it was determined that 63.1% of the women wanted to give birth in water. In the study, it was determined that 70.9% of the women had insuffic ient knowledge on water birth. Statistically signif icant correlations were found between the knowledge level of the pregnant women on water birth, and their ag e group, residence, education, employment status, fam ily income, registered health institution, number o f deliveries, level of education received on maternal he lth, and on water birth (for all: p<0.05). Conclusion: The research found that although pregnant women a r aware of water birth, their information level is not sufficient.


The workshop is based on results from the Nordic project CAGE (Coming of Age in Exile) and aims at creating a better understanding of how health, education and employment jointly play a role in the process of integration among young refugees. Results on patterns and trends regarding education, employment and health across the Nordic countries based on the unique Nordic register data will be presented along with analyses of Nordic health reception policies as well as qualitative studies on educational and labour market policies and practices related to young refugees in Norway and Finland.
 The Nordic countries are sharing quite similar general welfare schemes and other cultural and historical roots, but at the same time displaying different integration policies. By comparisons of some of the differences between otherwise similar countries we can identify possible effects of policy decisions and disentangle some of the complex processes forming the health and welfare trajectories of the young refugees that have arrived during recent decades.
 Nordic CAGE researchers have collaborated since 2015 in studies on similarities and differences between national health and welfare policies with a focus on their significance for refugee health and integration; these results have served as a framework for generating hypotheses and interpreting findings from studies on the different trajectories of the young refugees. Results from time and cohort analyses of comparable register data from each country have been further explained through the policy studies as well as the qualitative studies focusing on the experiences and perceptions of key actors involved in the integration processes.
 The workshop will include 5 short presentations (45 minutes in total) - the first introducing and motivating the focus on the interactive dynamics of health, education and employment followed by 4 presentations based on new evidence from the CAGE project. The participants will be invited to discuss the learnings from the Nordic results in an international perspective and their implications for integration policies for different groups of refugees in Europe (15 minutes).
 Presentations: Integration of refugees: the interactive dynamics of health, education and employment - a Nordic project, by Signe S Jervelund, 9 min.Educational trends, patterns of employment and selected health indicators among young refugees: results from a Nordic comparative analysis based on register data, by Andrea Dunlavy, 10 min.A healthy start: A comparative analysis of health reception policies for asylum-seeking and refugee children in the Nordic countries, by Camilla Michaëlis, 8 min.Young refugees' pathways in(to) education - Teacher and student voices: challenges, opportunities and dilemmas, by Ketil Eide and Hans A. Hauge, 9 min.Two-way labour market integration? Perspectives on youth with a refugee background and employers in Finland, by Eveliina Lyytinen, 9 min.

 Welfare policies related to refugees need to take into account the interrelations between inclusive health care, successful education and entrance into the labour markets. Multidisciplinary, international comparative studies can provide important new evidence on the role of different migration policies for the health and social trajectories of young refugees.


Measurement-based wide-band black-box transformer models are well suited for simulation studies of high-frequency transients in power systems. The inclusion of neutral points in such models can be difficult when the model is required to simulate voltage transfer to windings with high-impedance loads. The difficulty arises because it is then necessary to include the small winding capacitive currents in the measurement and model extraction procedure, while at the same time the capacitances can be asymmetrical with respect to the winding ends. This paper introduces a new measurement procedure which can accurately capture the effect of such capacitive asymmetries. The procedure is demonstrated for a wye-wye connected transformer. The measurement and subsequent passive rational modeling results in two alternative models. The first is a four-terminal model with bonded high-voltage and low-voltage terminals, suitable for simulation of lightning overvoltages in distribution systems. The second is a full eight-terminal model, suitable for general purpose transient studies.