Currently, the transplant crisis is one of the main concerns in the healthcare systems all over the world, the lack of donors and the persons which are on the waiting list for a transplant being higher from year to year. The diseases at the bone tissue level are affecting about 75M in USA, Europe and Japan, the need of treatments in this
field becoming clear. During the last decades, the USA spent more than 20 billion dollars on treatments for bone trauma and more than 300.000 spinal fusions were conducted only in 2005. Moreover, the International Osteoporosis Foundation stated that the number of hip fractures may increase by four by 2050. Therefore, considering the data reported for the last decades and the predictions made for the near future, there are two main directions which must be considered: the drawbacks of the current treatments and the economic impact of the available options. In this regards, Tissue Engineering is relatively new field in the regenerative medicine area, which aims to develop cost-effective alternatives for different diseases/trauma in order to restore the function of a tissue and to undertake the transplant crisis.


Recently, renewable energy sources (RESs) have increasingly being integrated into the power grids as a result of environmental and governmental perspectives. In this regard, installation of RESs as potential power resources in distribution systems would benefit the grid by decreasing the power losses, as well as addressing the fossil fuel shortages, and their environmental aspects. Nevertheless, the high-level integration of RESs as well as the development of distributed structures in local systems could challenge the reliable operation of the grid. In this context, conventional approaches could not optimally regulate the voltage in the grid; therefore, utilities have to exploit the scheduling of local responsive resources to address the voltage regulation issue in systems with high penetration of RESs. Consequently, the proposed scheme in this paper enables the distribution system operator (DSO) to activate flexibility service from local responsive resources with the aim of addressing the voltage regulation issue in the grid. Respectively, DSO as the leader provides incentive control signals to ensure collaboration of the independent agents in voltage regulation procedure. Finally, the developed framework is applied on the 37-bus IEEE test network to investigate its application in mitigating the voltage issue in the active distribution systems with multi-agent structures.


In the ethanol stillage biomethanation system a microbial fuel cell (MFC) is integrated in the anode area when combined with a process of aerobic photosynthesis of microalgae in the cathode zone. The dynamics of the main technological parameters in the area of the bioanode and biocathode of MFC has been established. Elimination of H2S from the composition of biogas has been achieved in the integration of the fuel products by achieving a higher degree of mineralization of the organic substrate under the load of fuel products compared to the modes of operation without electric load. The dynamics of the cathode potential during the different phases of photosynthesis has been established in the biocathode zone. Maximum values for power and current densities were achieved – 27.4 mW m-2 and 68 mA m-2, respectively, during the Log phase of the cultivation of oxygen microalgae.


If even those who undertake a brief vacation or recovery trip in their homeland like to be provided with a printed vademecum in which they can find advice on everything that is worth knowing—as the huge circulation of the travel guides by Baedeker, Berlepsch and many other authors conclusively proves—, how much greater must be the longing for such works among those starting long voyages across the ocean or even more those emigrating from their homeland for an indefinite period, maybe forever, to undertake a weeks-long journey to a country completely unknown to them in which they plan to settle. That which represents a mere convenience which the leisure or spa traveller would only reluctantly forgo, is absolutely necessary for the emigrant, since it very much depends on this whether can avoid his first steps on the ground of the new homeland proving to be missteps often followed by ominous consequences. For that reason it is almost incomprehensible that nobody has yet conceived the obvious idea of offering a reliable, handy and also relatively inexpensive guide that gives to the thousands of people who leave Europe every year, hastening to the hospitable shores of this country, comprehensive information on everything that might be important for travellers of different classes, especially for immigrants, and allows them to find their way into and through this country without depending on outside help (Kunz 1890a: n. pag.). Although Hugo Kunz actually presented the most extensive work up to 1890, from the middle of the 19th century numerous guidebooks [1] for German-speaking emigrants had been published with the objective of preparing them for the journey across the ocean and the conditions that awaited them in their new homeland. They were usually penned by authors who had known the South American country for many years and wanted to win their compatriots over to follow suit and dare to take the step into the new world. Whether they worked as government agents like Philippi, were founding private colonies like Kindermann or, like Ried, just wanted to make other German-speaking settlers aware of this far-away country, the authors of all these publications praised the advantages that the future colonists could expect to find in Chile, the South American land offering the best prospects, as was often emphasized. Among these advantages were a favourable climate for agriculture, the fertile soils, the many year-long tax exemptions and the ease of obtaining Chilean citizenship. The objective of this essay is to trace what role the Chilean landscape played in the migration guides as an element of publicity for the country. To that purpose the paper will first briefly deal with the development and extent of German-speaking immigration to Chile. An analysis of the migration guides as sources of this history of migration will follow, and finally the focus will be on their presentation of the Chilean landscape.


Intricate branching patterns emerge in internal organs because of the repetitive presence of simple deformations in epithelial tissues. During murine lung development, epithelial cells in distal tips of a single tube require fibroblast growth factor (FGF) signals generated by their surrounding mesenchyme to form repetitive tip bifurcations. However, it remains unknown how the cells employ FGF signaling to convert their behaviors to achieve the recursive branching processes. Here we show a self-sustained epithelial regulatory system during the murine lung branching morphogenesis, mediated by extracellular signal-regulated kinase (ERK), which acts as a downstream driver of FGF signaling. We found that tissue-scale curvature regulated ERK activity in the lung epithelium using two-photon live cell imaging and mechanical perturbations. ERK was activated specifically in epithelial tissues with a positive curvature, regardless of whether the change in curvature was attributable to morphogenesis or artificial perturbations. Moreover, ERK activation accelerated actin polymerization specifically at the apical side of cells, and mechanically contributed to the extension of the apical membrane, leading to a decrease in epithelial tissue curvature. These results indicate the existence of negative feedback loop between tissue curvature and ERK activity beyond scale. We confirmed that this regulation was sufficient to generate the recursive branching processes by a mathematical model. Taken together, we propose that ERK mediates the curvature feedback loop underlying the process of branching morphogenesis in developing lungs.


bound when physical barriers such as stairs and access to public transport make attendance at theatre, church, or sporting events well-nigh impossible. Much has yet to be done to overcome the barriers which prevent handicapped people from pursuing leisure activities outside the home and enjoying other people's company. However, libraries can bring entertainment to the home, and other local Council and community services provide meals on wheels, shopping services and visiting and emergency housekeeping services. Regional Community Health Services and some large hospitals have community teams to carry out home assessments and coordinate such services. Hospitals with large outpatient clinics which provide regular care require the occupational therapist to assessand advise patients both immediately after the initial diagnosis and on a long term basis to ensure that the patients receive maximum help with their home management, personal care and daily living. The Occupational Therapy Department is continually reviewing both commercially available aids and appliances and specially made aids and appliances as well as techniques for treatment of people with rheumatic diseases. The help able to be provided is made more wide-ranging in most States through coordination with lay organizations: for instance, in New South Wales, the Arthritis and Rheumatism Council in conjunction with the Jaycees runs an advisory stand, "Aids for Daily Living", which is set up in community shopping centres and other focal points on Saturday mornings. This same organization will shortly produce an information booklet which will describe useful aids which are commercially available. The booklet will include details of cost and of how to obtain the aids. General information can be obtained through inquiry to national organizations such as the Australian Council for Rehabilitation of the Disabled (ACROD), and Technical Aids for the Disabled (TAD).


Abstract The Arabic manuscripts of Timbuktu have received considerable publicity during the past 25 years, yet their contents remain largely unknown. Since 2012, an inventory of nearly 350,000 Timbuktu manuscripts in private libraries has been underway, and the contents of those libraries are now accessible in the West African Arabic Manuscript Database (WAAMD). This analysis examines 31 of the 35 libraries and in addition to reporting on their contents, notes challenges in accessing incompletely identified works, and compares the manuscripts with other West African collections.


The rapid development of the real estate market in China has resulted in many powerful real estate enterprises, whereas become increasingly saturated. It is urgent to open up the international market while opportunities and challenges coexist in the globalization process of real estate enterprises. Furthermore Chinese real estate enterprises lack experience in international investment, and it is of great practical significance to formulate a reasonable overseas investment strategy. This paper introduces the current situation of foreign investment in Chinese real estate enterprises, and applies SWOT analysis to carry out research on the overseas investment strategy of real estate enterprises in China, which will inspire and help many of the real estate enterprises in China to growth continuous and healthy.


This thesis is a comparative research into the ways of describing "Hyang-rang" in Hyang-rang biography and Hyang-rang legend. Hyang-rang was a 17-years-old commoner who lived in Sunsan, Kyungsangbuk-do of latter Chosun dynasty. Her step mother and her husband treated her badly and her uncle urged her to remarry. She drowned herself as she didn`t want remarry and nobody would like to live with her. To hear her death, 10 male writers wrote her biography to honour her faithfulness. In their biographies, The death of Hyang-rang was ``systematized`` in the context of provincial faithful tradition and Hyang-rang was described as the incarnation of Confucian ethics. Distinctively, in the legend, there was romanticism instead of such faithfulness. In the legendary world, Hyang-rang was good, pretty and poor girl and just a victim of the feudal family system. So she was a person not for reverence but sympathy. These differences generally mean the differences between biography and legend. But the important things are two viewpoints have struggled from then on and the viewpoint of the legend provides us more balanced eye for "Hyang-rang".


In this research, we show two experiments using non-verbal interaction which construct natural interaction between human and systems. Recently, we use various types of systems based on electronics. However, these systems are not useful and imposes burden. we think nonverbal communication is important for natural communication between human and system. Moreover, We focus on the networked robotics which is fusion of network technology and robot technology. We constructed nonverbal interface by using human natural motion. In the first experiment, in order to manipulate a robot using more natural motion, we proposed 'pointing movement'. Moreover, we constructed networked robots that recognizes human motion spatially. Accordingly, the user will be able to manipulate the robot with natural motion in large space. In the second experiment, for making a system more natural and friendly, the system replies to the user by blinking the pointed object in the virtual room screen, confirming the user's intention.


The purpose of this study was to identify and describe the role of the Village Community Empowerment Institution (LPMK) in accommodating and channeling community aspirations in development in Mamasa Village, Mamasa Regency and the role of the Village Community Empowerment Institution (LPMK) in increasing community participation in development in Mamasa Village, Mamasa Regency. The type of research used is descriptive qualitative research. The results of the study indicate that the role of LPMK in accommodating and channeling community aspirations has not been maximized. LPMK does not schedule the right time to hold a meeting with each head of the environment, so it is not effective in conveying the aspirations of each head of the environment to LPMK.


Objective To investigate the relationship of serum uric acid(SUA)concentration with the components of metabolic syndrome(MS).Methods A population-based and cross-sectional survey on 865 subjects with metabolic syndrome was performed in adults aged 20-74 years in Jiangsu Province.MS was defined by IDF-2005.Anthropometry data and levels of UA and lipid file were collected.Results Correlation analysis demonstrated that serum uric acid level was positively correlated with waist circumference(WC)(r=0.31,P0.01),systolic BP(r=0.20,P0.01),diastolic BP(r=0.21,P0.01),serum triglyceride(r=0.29,P0.01),fasting blood glucose(r=0.15,P0.05),HOMA-IR index(r=0.31,P0.01)as well as the number of MS componts,and negatively correlated with high-density lipoprotein cholesterol(r=-0.09,P0.05).Conclusions Serum uric acid concentration is correlated with each of components and the number of components of metabolic syndrome,but may not be an independent risk factor for MS.


Since tree morphological structure is strongly influenced by internal genetic and external environmental factors, accurate simulation of individual morphological–structural changes in trees is the premise of forest management and 3D simulation. However, existing studies have few descriptions, and the research on the impact of growth environments and stand spatial structures on tree morphological structure and growth is still limited. In our study, we constructed a comprehensive grade model of spatial structure (CGMSS) to comprehensively evaluate individual tree growth states of the stands and grade them from 0 to 10 correspondingly. In addition, we developed a Chinese fir morphological structure growth model based on CGMSS, and dynamically simulate the growth variations of Chinese fir stands. The results showed that the overall stand prediction accuracy of CGMSS-based Chinese fir diameter at breast height, tree height, crown width and under-living branch height growth models was more than 94%. According to the analysis of the comprehensive grade of spatial structure (CGSS) of trees in the stand, except for the prediction accuracy and systematic error of the under-living branch height growth model at the CGSS = 3–5 levels, the systematic error of the Chinese fir growth model at each level was lower than 21.2%, and the prediction accuracy was greater than 73%. Compared with the spatial structural unit (SSU)-based Chinese fir growth model proposed by Ma et al., all growth models fit better at all levels, except for the CGMSS-based Chinese fir tree height and under-living branch height growth models that fit significantly lower than the SSU-based Chinese fir growth model at CGSS = 3–5 levels. In this study, the main conclusion is that the simulation results of CGMSS's Chinese fir morphological structure growth model are closer to the real growth state of trees, achieving accurate simulation of differential growth of trees in different growth dominance degrees and spatial structure states in forest stands, making visualized forest management more effective and realistic.


This paper designs the scheme of LWD (Logging With Drilling) Data Remote Transmission System based on GPRS.First, the paper introduces the GPRS technology in the remote transmission system application, and then describes system components, business processes, implementation process of LWD Data Remote Transmission System Based on GPRS in detail, and the application effect of LWD Data Remote Transmission System Based on GPRS.


Snowpack is highly variable across different scales of terrain and with changing land cover. Previous research has used various terrain properties, such as elevation, slope, aspect, northness, occasionally at different resolutions, to estimate the distribution of snowpack properties. Snow depth is among the easiest snowpack properties to measure, and average values are used to determine the spatial distribution of snow. Here we investigate the variability of snow depth for two watersheds on Byers Peninsula of Livingston Island in the South Shetland Islands of Antarctica by taking multiple measurements to represent a single point. We use several techniques to quantify variability and show that scaling is more crucial with some quantification methods than with others. We can use the preferred methods to determine the resolution of future sampling strategies.


Nafion/carbon nanotube (CNT) nanocomposites were prepared and their thermoelectric properties were measured at room temperature. Three different CNTs, i.e., single walled CNT (SWNT), thin walled CNT (TWNT), multi walled CNT (MWNT), were dispersed in the aqueous solution of Nafion. Electrical conductivity and Seebeck coefficient of the nanocomposites were measured as a function of CNT concentration at room temperature.


Introduction Electron miscroscopic studies of the central nervous system have emphasized the virtual absence of detectable extracellular spaces. 1-4 These observations have provoked dissatisfaction with the chloride ion as an indicator of the extracellular space of brain. Calculations based on the assumption that chloride is entirely extracellular would indicate a compartment amounting to approximately 30% of brain weight. 5 Although an extracellular space of this order of magnitude is clearly untenable, it seems to us that it is equally unreasonable to interpret the electron photomicrographs too literally and thus conclude that there is essentially no fluid outside of cellular membranes. Resolution of these widely different findings is important to the understanding of the transfer of substances into brain as well as such neuropathologic phenomena as cerebral edema. A more satisfactory indicator of extracellular brain water is required and we have investigated the sulfate ion with this in view. S 35


The utility model discloses a transverse power output system of a horizontal single-cylinder diesel engine. A power output shaft of a conventional horizontal single-cylinder diesel engine and a steam cylinder form a 90-degree angle, and size of the horizontal single-cylinder diesel engine is enabled to be too long due to the steam cylinder and a crankshaft box, the horizontal single-cylinder diesel engine has to be mounted longitudinally on agricultural machinery, power of a flywheel is transmitted through a belt, and belt transmission is prone to slipping, large in friction force and high in power consumption, so that using cost is increased. In order to solve the above problem, the transverse power output system is invented. A set of bevel gears are additionally mounted between a crankshaft and the flywheel of an original horizontal single-cylinder diesel engine, and the power is transmitted to the power output shaft through the bevel gears, so that shaft transmission is realized easily, effect of no slipping, small friction force and reducing of power loss in the process of transmission is realized, using cost is lowered, and using space is smaller when the diesel engine is mounted longitudinally.


The undoped titanium dioxide (TiO2) and zinc-doped TiO2 gels were prepared by sol–gel method. The nano-TiO2 powders were prepared by controlling the sintering temperature. The phase compositions of the sintered samples were analysed by powder X-ray diffraction; the microstructure was analysed by high-resolution transmission electron microscope; the photocatalytic activity was analysed by photochemical reactions instrument. The combined action of Zn2+ doping and heat treatment on phase transformation and photocatalytic performance of TiO2 were analysed. The results show that, when the Zn ion doping amount is within 1–5 mol%, it promotes the conversion of anatase to rutile transition as the presence of ZnTiO3. The photocatalytic performance of TiO2 sintered at 700°C is better than sintered at 400°C.


Reproducibility is a core tenant of scientific enquiry, including the study of governance and government outputs. Having full access to the data and procedures that researchers used to study a phenomenon is vital for being able to understand and trust their findings. This chapter sets out best practices for the reproducibility of governance indicators. For a governance indicator project to be 'really reproducible', the full data as well as data gathering and analysis procedures should be easily and persistently accessible. Indicator development should be fully documented, especially via a version control system. The chapter surveys the status quo level of reproducibility among prominent governance indicator projects. While most had some reproduction material available, none were really reproducible. The chapter concludes with recommendations, including calling for a shared governance indicator hosting service that focuses on encouraging reproducibility.


The long-termmanagement ofmaintenance immunosuppression in kidney transplant recipients remains complex. The vast majority of patients are treated with the calcineurin inhibitor tacrolimus as the primary agent in combinationwithmycophenolate, with or without corticosteroids. A tacrolimus trough target 5–8 ng/ml seems to be optimal for rejection prophylaxis, but long-term tacrolimus-related side effects and nephrotoxicity support the ongoing evaluation of noncalcineurin inhibitor–based regimens. Current alternatives include belatacept or mammalian target of rapamycin inhibitors. For the former, superior kidney function at 7 years post-transplant comparedwithcyclosporingenerated initial enthusiasm,bututilizationhasbeenhamperedbyhigh initial rejection rates.Mammalian target of rapamycin inhibitors have yieldedmixed results aswell,with improved kidney function tempered by higher risk of rejection, proteinuria, and adverse effects leading to higher discontinuation rates. Mammalian target of rapamycin inhibitorsmayplay a role in the secondarypreventionof squamouscell skin cancer as conversion froma calcineurin inhibitor to anmammalian target of rapamycin inhibitor resulted in a reduction of new lesion development. Early withdrawal of corticosteroids remains an attractive strategy but also is associated with a higher risk of rejection despite no difference in 5-year patient or graft survival. Amajor barrier to long-term graft survival is chronic alloimmunity, and regardless of agent used,managing the toxicities of immunosuppression against the risk of chronic antibody-mediated rejection remains a fragile balance. CJASN 16: ccc–ccc, 2021. doi: https://doi.org/10.2215/CJN.15040920 Introduction The long-term management of immunosuppression remains a tale of immediate gratification followed by frustrations and occasional disappointment. The introduction of calcineurin inhibitors and mycophenolate as immunosuppressive therapies began an era of improved maintenance immunosuppression efficacy. Short-term acute rejection rates decreased, and 1-year outcomes improved. Despite this short-term success, long-term kidney allograft survival has frustratingly not enjoyed a similar rate of improvement (1). In evaluating this discrepancy of shortversus long-term outcomes, it is apparent that the same maintenance immunosuppression that provides excellent shortterm results may contribute to graft attrition with long-term exposure. In this review, we evaluate the current state of maintenance immunosuppression in kidney transplant recipients and discuss areas of opportunity and uncertainty in their long-term use. Ideal Calcineurin Inhibitor Targets The current standard of care in kidney transplant immunosuppression in the United States has evolved to be a calcineurin inhibitor–based immunosuppression regimen with tacrolimus and mycophenolate. Over 90% of patients in the United States are maintained on these two agents, with or without steroids (2). This is largely attributed to the landmark Symphony trial, which demonstrated superior outcomes in terms of both acute rejection rates and GFR at 1 in 3 years using a tacrolimus-based regimen when compared with cyclosporinor sirolimus-based regimens (3), and historical studies that support mycophenolate over azathioprine due to reductions in early acute rejection rates (4). However, there remains ongoing debate regarding the appropriate dose of tacrolimus and appropriate mycophenolate exposure for optimal immunosuppression in the long term. Importantly, in the Symphony trial, although tacrolimus trough (tacrolimus C0) level goals were protocol specified at 3–7 ng/ml, the actual achieved tacrolimus C0 exposure averaged 6.4 ng/ml at 12 months and 6.5 ng/ml at 36 months. Thus, a more appropriate interpretation of the Symphony trial is that a tacrolimus C0 dose range of 5–8 ng/ml should be considered the standard of care. Regarding mycophenolate exposure, attempts to define appropriate dose/exposure have not been fruitful, with the best attempt at defining optimal dose residing in the OPTICEPT trial in which a concentration-controlled dosing with reduced calcineurin inhibitor exposure was noninferior to standard calcineurin inhibitor/mycophenolate dosing for prevention of acute rejection (5). Compounding this lack of guidance is a paucity of data supporting improvements in graft or patient survival over time with mycophenolate compared with azathioprine (6). No study to date has demonstrated superior outcomes with low-dose tacrolimus exposure ,5 ng/ml Department of Medicine, University of Texas Southwestern


This essay ponders on the relationships between authors and literary critics in the contemporary literary field which is often in a state of conflict. It gives special consideration to the so-called "Echevarria case" (2004), in which the critic Ignacio Echevarria was confronted by the newspaper El Pais (Spain). This ultimately led to his resignation due to a clash of cultural, economical, as well as ideological interests. It closes with an analysis of Roberto Bolanos literary project and points out the poetological necessity of protecting it from literary criticism, especially considering that the novel Detectives salvajes (1998) is narrated through the characters Arturo Belano (author) and Inaki Echevarne (literary critic).


In the present paper, we introduce and investigate an interesting subclass K λ s (h) of analytic and close-to-convex functions in the open unit disk U . For functions belonging to the class K λ s (h) , we derive several properties as the convolution, the coefficient bounds, the covering theorem, the inclusion relationships as well as distortion theorem. The various results presented here would generalize many known recent results.


New associations have been established in biotechnology within the last 10–15 years in a process influenced by industry, academic institutions and government agencies. Different models and strategies have been applied across Europe, and the part played by industry, academia and government varies significantly. Although national arrangements have been sustained, a common feature is that interests outside industry were more important in the formative stage than in the later stages where membership was increasingly drawn from industry alone. To understand the dynamics behind these developments, inspiration must be sought beyond the framework of neo-corporatism and network studies. Copyright , Beech Tree Publishing.


A great struggle started in Anatolia during the period following the World War I and this struggle was made against the external powers who attempted to break up the Anatolian territory. The newspaper Irade-i Milliye was published in 17 September 1919 in order to prove the righteousness of the struggle and to announce the problems suffered by the people of Anatolia. The movement initiated in Anatolia by the means of Newspaper was started to be heard by everyone. Then, the newspaper designated by Mustafa Kemal as Hakimiyet-i Milliye published in 10 January 1920. The newspaper Hakimiyet-i Milliye was published with the name "Ulus" since 28 November 1934 and started to be respected with the official publication of Government. In the Ulus Newspaper, Atay has written many articles on domestic and foreign relations. In this study, many issues of the Ulus newspaper between 1935-1937 were scanned, Beloning to Atay's were read and evaluated. During the study, it was seen that the newspaper was a media organ that fingers on the pulse of the world and the country, and that the articles written by Atay revealed the internal and external events in the world and analysed the events.


Using the real-space renormalization group (RSRG) scheme of Ghosh and Karmakar [Phys. Rev. B 58, 2586 (1998)], we analytically determine the trace-map relation for a general spring-mass model of the aperiodic Thue-Morse (TM) lattice, and, interestingly observe that this map has a pseudoinvariant. This pseudoinvariant has a crucial role on the nature of the eigenmodes of this lattice. When the pseudoinvariant vanishes identically, as in the case of the on-site, transfer, or mixed model of the TM lattice, all normal modes are found to be delocalized, whereas the eigenmodes are critical for more general models with nonzero pseudoinvariant. Our RSRG scheme also gives the average phonon density of states $\ensuremath{\rho}(\ensuremath{\omega})$ and Lyapunov exponent $\ensuremath{\gamma}(\ensuremath{\omega})$ (= inverse localization length) of the eigenmodes.


To manage these tensions researchers need to engage in reflective and reflexive analysis (Finlay, 2003) moving back and forth in a kind of dialectic between experience and awareness; between studying the parts and the whole. As researchers, we need to strive, explicitly, to understand some of the connections by which subject and object influence and constitute each other. We need to acknowledge both our experience and our experiencing.


Hematopoietic stem cell transplantation (HSCT) and mesenchymal stromal (MSC) cell therapy are currently under investigation as novel therapies for inflammatory bowel diseases (IBD). Hematopoietic stem cells are thought to repopulate the immune system and reset the immunological response to luminal antigens. MSCs have the capacity to differentiate into a wide variety of distinct cell lineages and to suppress immune responses in vitro and in vivo. The main goal of this thesis was to study the safety, feasibility, and applicability of stem cell therapy in IBD.
Chapter 2 concludes that autologous HSCT appears to be safe and can be an alternative strategy for Crohn's disease patients with severe and therapy resistant disease. Data from the phase I study described in Chapter 3 demonstrates that MSCs isolated from Crohn's disease patients have similar characteristics compared to MSCs from healthy donors and that administration of autologous bone marrow derived MSCs appears to be safe and feasible in the treatment of refractory Crohn's disease. Chapter 4 shows that MSC phenotype and function are not affected by therapeutic concentrations of drugs commonly used in the treatment of IBD. Chapter 5 demonstrates that IFN-γ activation of MSCs increases their immunosuppresive capacities and importantly, their therapeutic efficacy in vivo.


It is necessary for a researcher to identify the effect of buckle on diverse structures. The reason behind the issue is most of the successful designs fail at the practical application. In this paper, a solid Kevlar structure container various layers has been designed and analyzed thermally its buckling effect with or without a hole using ANSYS and FET. A circular cylindrical shell elliptical headed container is considered due to its outstanding demand in the pressure vessel and automobile engineering. The attention-grabbing stage of buckling phenomena occurs before the deformed or non-deformed and a partial deformed sometimes contour of structure. Finally, concluded with pros and cons of using Kevlar composites in high temperature environment.


Abstract:The recent emergence of horror-satires marks a new moment in cinematic representations of Israel/Palestine. Rather than violence of war, these films foreground structural violence within privileged segments of Israeli society through tropes of infectious diseases and solitary sociopaths. This article examines two widely acclaimed films, Rabies and Big Bad Wolves, to argue that cynicism has replaced reverence over Israel's foundational myths and institutions. A younger generation of filmmakers and audiences is willing to consider Israel's role as both victim and victimizer; their horror-satires replace fears of outside dangers with fears of attacks inside individual and social bodies.


This paper addresses the problem of reengineering object-oriented systems that have incurred increased maintenance cost due to long development time-span and project lifecycle. When an Incremental Approach is used to develop an object-oriented system, there is a risk that the class design and the overall object model will deteriorate in quality with each increment. A recent research work suggested a process activity (Class Deterioration Detection and Resurrection-CDDR process activity) and a technique for the detection and resurrection of deteriorated classes. That work focussed on one particular aspect of object-oriented software maintenance-Class Quality Deterioration due to lack of cohesion induced by high coupling. This paper addresses the problem of deteriorating object-oriented design due to code and class growth (increase in the number of classes) within a system. A Code/Class Growth Control process activity (CGC) is suggested to avoid and eliminate Repetitious Code and Classes within the evolving system. The CDDR and CGC process activities are used to build an evolving Maintenance process model for object-oriented systems. The presented maintenance process model is an effective way to periodically assess and resurrect the quality of an object-oriented design during incremental development.


A new moving object detection algorithm based on edge subtraction is proposed to solve the problem of moving object detection in video sequences.Firstly,two edge images are detected from two adjacent frames through an improved object detection algorithm and subtracts the former from the latter,and then a meliorative Otsu method is used to determine the threshold of edge subtraction image,finally the result of moving object detection is acquired after threshold segmentation.Edge images obtained by the edge detection algorithm integrating Prewitt operator with Sobel operator have abundant texture and notable details,and the results of edge subtraction are more ideal.The meliorative Otsu method combined with within-class variance restrains noise well and reserves more details.The computer simulation demonstrates that the target regions detected by this method are more complete and distinguishable with less noise.Compared with some methods proposed recently,it performs better particularly when the images have illumination changing and background moving.


In the present paper,a new species of freshwater razor clam, Novaculina chinen-sis, is described. The materials studied weie collected by the authors and Mrs. GongHui-qing from Wu-xi,Jiangsu Province in 1973 and 1974. Novaculino chinensis, sp. nov. Shell oblong, small. equivalve, inequilateral, anterior end rounded, posterior endtruncated. Shell about three times as long as high. Snrface wrinkled with growthlines, epidermis yellowish-green, folding over in the edge and extremities of the shell. Interior of shell non-nacreous, whitish. Anterior .adductor muscle scar narrow,elongate-triangular, posterior adductor muscle scar wide, broadly triangular. Pallialimpression defined. Pallial sinus broad and deep, anterior end obtusely rounded, ex-tending anteriorly to 2/5 of the length of shell, its lower line united with pallialimpression in most of ito posterior part. Holotype (KS 747703) Length 35 mm, height 12 mm, diameter 15 mm; Wu-xi,Jiangsu Province; July, 1974. Paratypes Length 34--46 mm) height 11--16 mm, diameter 8--10 mm; Wu-xi,Jiangsu Province; July, 1974. Holotype and Paratypes are deposited in the Institute of Zoology, AcademiaSinica. The present species is related to Novacolina gangetica Benson 1830, but differsfrom the latter by the larger shell, the more rounded pallial sinus and the lower pal-lial sinus line being united with pallital line in most of its posterior part.


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	    </jats:inline-formula>, is asymptotic to <jats:inline-formula>
	      <jats:alternatives>
		<jats:tex-math>$\Lambda (x,\,y)$</jats:tex-math>
		<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" xlink:href="S0308210523001154_inline7.png" />
	      </jats:alternatives>
	    </jats:inline-formula> when <jats:inline-formula>
	      <jats:alternatives>
		<jats:tex-math>$y \ge (\log x)^{2+\varepsilon }$</jats:tex-math>
		<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" xlink:href="S0308210523001154_inline8.png" />
	      </jats:alternatives>
	    </jats:inline-formula>. We extend the range to <jats:inline-formula>
	      <jats:alternatives>
		<jats:tex-math>$y \ge (\log x)^{3/2+\varepsilon }$</jats:tex-math>
		<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" xlink:href="S0308210523001154_inline9.png" />
	      </jats:alternatives>
	    </jats:inline-formula> by introducing a correction factor that takes into account the contributions of zeta zeros and prime powers. We use this correction term to uncover a lower order term in the asymptotics of <jats:inline-formula>
	      <jats:alternatives>
		<jats:tex-math>$\Psi (x,\,y)/\Lambda (x,\,y)$</jats:tex-math>
		<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" xlink:href="S0308210523001154_inline10.png" />
	      </jats:alternatives>
	    </jats:inline-formula>. The term relates to the error term in the prime number theorem, and implies that large positive (resp. negative) values of <jats:inline-formula>
	      <jats:alternatives>
		<jats:tex-math>$\sum _{n \le y} \Lambda (n)-y$</jats:tex-math>
		<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" xlink:href="S0308210523001154_inline11.png" />
	      </jats:alternatives>
	    </jats:inline-formula> lead to large positive (resp. negative) values of <jats:inline-formula>
	      <jats:alternatives>
		<jats:tex-math>$\Psi (x,\,y)-\Lambda (x,\,y)$</jats:tex-math>
		<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" xlink:href="S0308210523001154_inline12.png" />
	      </jats:alternatives>
	    </jats:inline-formula>, and vice versa. Under the Linear Independence hypothesis, we show a Chebyshev's bias in <jats:inline-formula>
	      <jats:alternatives>
		<jats:tex-math>$\Psi (x,\,y)-\Lambda (x,\,y)$</jats:tex-math>
		<jats:inline-graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" xlink:href="S0308210523001154_inline13.png" />
	      </jats:alternatives>
	    </jats:inline-formula>.</jats:p>


For high-precision position and angle control in robots, it is essential to compensate for the hysteretic behaviour caused by friction when the motion direction is reversed. An accurate friction model which is suitable for control system analysis and implementation is highly desirable. A differential model is proposed in the current paper for the modelling of hysteresis effects caused by friction phenomena. The model is constructed by employing a phenomenological phase-transition theory to mimic the friction mechanism. The bristle friction mechanism is adapted. The switching between static and dynamic friction is regarded as a reversible phase-transition phenomenon, which could be characterized by the local minima of a non-convex potential energy function. The Stribeck effect and the hysteretic relation between friction and velocity are modelled by a nonlinear ordinary differential equation. The comparison of the numerical simulation results and existing experimental friction data are presented. It is illustrated that the friction hysteresis loops are well captured, the capability of the proposed model is verified.


OBJECTIVE To analyze the bacteriological efficacy of gatifloxacin methanesulfonate tablet on acute bacterial infections. METHODS Levofloxacin hydrochloride tablet was used as a control drug and a randomized controlled multicenter clinical trial was conducted to evaluate the bacteriological efficacy of gatifloxacin methanesulfonate tablet on acute bacterial infections. RESULTS The bacterial positive rates in the gatifloxacin group and the levofloxacin group were 77.42 % and 80.99%, respectively, and the bacterial clearance rates were 97.92% and 97.96%, respectively. The efficacy rates of two groups against different bacterial infections were 83.33-100% and 80-100%, respectively. The differences of the results were not statistically significant (P0.05) . The susceptible rates of bacterial isolates to gatifloxacin,levofloxacin,ofloxacin, ciprofloxacin and sparfloxacin were 93.81%, 93.30%, 91.24%, 84.54% and 87.11%, respectively. The antibacterial activity of gatifloxacin was higher than that of levofloxacin from the results of MIC 90 . CONCLUSIONS Gatifloxacin methanesulfonate tablet has good bacteriological efficacy.


The objectives of this study are the development and verification of a simulation model of the partial PST (power-shift transmission) tractor based on actual field operations. The PST simulation model was verified for the asphalt driving condition, and performance was evaluated for asphalt driving, plow, and rotary tillage. In this study, the traditional, APS (Auto Power Shift) ECO, and APS power engine modes were used to analyze fuel consumption. The statistical analysis proved that the experimental and simulation results were in a linear relationship, with an accuracy of over 98%. Finally, the results suggested that users could utilize the 95-kW partial PST tractor in the APS ECO engine mode with higher fuel economy compared to the traditional and APS power modes.


A notion of so-called analytic equivalence is considered, in the form of Suszko's connective of propositional identity. Two axiomatic strengthenings of the Sen- tential Calculus with Identity of Suszko involving that connective are presented. Both realize the following principle due to Wojcicki: two sentences whose logical forms in sentential language are logically equivalent and have the same sentential variables, express the same proposition. The paper is devoted to some axiomatic strengthenings of the SCI logic of Suszko. These logics can be viewed as possible formalizations (in the framework of Suszko) of some important notion of the identity of proposi- tions expressed by sentences (or situations described by sentences). This notion was introduced by Wojcicki in (13) (however mentioned earlier in (11, 12) and later independently considered by Vanderveken, cf. for exam- ple (8, 9) and Bi lat (3, 4)) by means of the principle: two sentences whose logical forms in sentential language are logically equivalent and have the same sentential variables, describe the same situation (that is, according to our understanding, express the same proposition). Wojcicki's principle (hereafter called WP ) on the one hand, is a particularization of the princi- ple considered by Barwise and Perry (1): two sentences whose logical forms are logically equivalent and have the same extralogical constants, desribe the same situation, on the other hand, is a weakening of some criterion of identity of propositions known in Polish literature as Wittgenstein's prin- ciple (cf. (10)): two sentences whose logical forms are logically equivalent express the same proposition. Nowadays Wittgenstein's principle is rather rejected as leading, in a presence of some other principles, by so-called


Grapevine water status of Vitis vinifera cvs. Riesling, Cabernet franc, and Pinot noir was evaluated in Ontario, Canada, using leaf water potential (Ψ) and surface soil water content (SSWC; %) to examine spatial relationships between soil and vine water status and berry composition variables, particularly secondary metabolites. The goal was to assess their significance as drivers of the terroir effect. Research was conducted over two vintages (2014 and 2015). Strong inverse relationships were found between vine water status and total phenols in Cabernet franc and Pinot noir and monoterpenes in Riesling. Leaf Ψ was associated with berry size, while yield had strong negative correlations with pH and (in most cases) positive correlations with vine size. Principal component analysis complemented with k-means clustering identified relationships between variables, while Moran's index also indicated strong clustering patterns for SSWC. Both SSWC and leaf Ψ showed weak correlations with each other. Overall, leaf Ψ was a stronger indicator of important secondary metabolites (anthocyanins, phenols, color, and monoterpenes) than SSWC.


— A self-association model has been used to understand the concentration dependence of free energy of mixing (G M ), heat of mixing (H M ), entropy of mixing (S M ), activity (a) and microscopic structures, such as concentration fluctuation in long wavelength limit (S cc (0)) and Warren-Cowley short range order parameter ( 1 α )for Cu-Tl molten alloys at 1573K. A comparative study of surface tension of the alloys in the liquid state at that temperature has also been carried out theoretically as function of composition in the light of Butler's model, Prasad's model and quasi-chemical approach. Most of the computed thermodynamic properties have been found in agreement with the experimental values. The analysis reveals that the Cu-Tl molten alloys at 1573K represent a segregating system at all concentrations with moderate interaction. Surface tensions computed from different approaches have been found to be comparable to each other showing increment with the composition of copper.


In particular, in the capsule (1) designed to prepare a beverage by centrifugation of the capsule in centrifugal preparation device, - a body (2) provided with a storage wall surrounding the central axis of the main cavity (6) of (I), - a lid (7) associated with the body for enclosing the compartment containing the beverage raw material, wherein the capsule further comprises a frangible plurality of outlet area is located in the body, The frangible outlet region is located at a constant distance from the central axis (I), (A) said cover a predetermined opening (8, 15) in the containment walls or the lid, frangible dedicated film which is connected to the wall or lid (9, 16), (B) the storage cover a predetermined opening in the wall or lid, dedicated film connected by frangible seal joined to the wall or lid, (C) at the frangible outlet region, wherein the containment walls or lid, dedicated, fragile, the thickness of the material is reduced are localized, (D) any possible (a), (b), obtained by any of the methods of the combination of (c), the capsule. .FIELD 1


Web citations have become common in scholarly publications as the amount of online literature increases. Yet, such links are not persistent and many decay over time, causing accessibility problems for readers. The present study investigates the link decay phenomenon in three leading information science journals. Articles spanning a period of seven years (1997 to 2003) were downloaded and their links were extracted. From these, a measure of link decay, the half-life, was computed to be approximately five years which compares favorably against other disciplines (1.4 to 4.8 years). The study also investigated types of link accessibility errors encountered as well as examined characteristics of links that may be associated with decay. It was found that approximately 31% of all citations were not accessible during the time of testing and the majority of errors were due to missing content (HTTP error code 404). Citations from the edu domain were also found to have the highest failure rates of 36% when compared with other popular top-level domains. Results indicate that link decay is a problem that cannot be ignored and implications for journal authors and readers are discussed.


Objective To investigate the distribution and drug resistance profiles of clinical isolates in Xiangya hospital in 2003 and to provide guidance for the proper use of antibiotics. Method Bacteria identification and susceptibility test were performed by Microscan system and K-B disk method,and the statistical analysis was performed by SPSS software. Results Among the 3,747 clinical isolates collected in 2003 from Xiangya hospital,gram-negative bacilli(G~-)and gram-positive cocci(G~+)accounted for 54.8%(2,052/3,747) and 43.5%(1,629/3,747) respectively.The Pseudomonsa aeruginosa, Escherichia coli,Klebsiella pneumonia,Acinetobacter baumannii and Enterobacter cloacae were the most common pathogens among the gram-negative bacilli.The resistance rate of these strains to meropenem was only 0%~6.4%,which was the lowest;and followed by cefoperazone/sulbactam.The resistance rate of gram-negative bacilli to other common antibiotics was from 4.4% to 85.9%.The coagulase negative Staphylococci(CNS) accounted for 57.0%(929/1,629),which was the most common among the G~+ cocci.Among Staphylococcus aureus(SA) and CNS,resistant isolates to methicillin accounted for 55.1% and 61.7% respectively;but the vancomycin-resistant(VRE) or intermediate strains were not found.Deoxycycline was the effective antibiotics against Staphylococcus second to vancomycin.The resistance rate was(2.8%)~4.4%,and the resistance rate to erythromycin,SMZ-TMP and azithromycin was from 73.3% to 88.6%. Conclusion Staphylococcus,Enterobacteriaceae,Pseudomonsa aeruginosa, Acinetobacter baumannii and Enterococcus are the most common pathogens isolated from Xiangya hospital,and the drug resistance profiles of clinical isolates are substantial.We should strengthen resistance monitoring of clinical isolates and use antibiotic reasonably.


Hypogene mineralization at the Quebrada Blanca (QB) porphyry Cu deposit is not well understood because the current resource includes only supergene enrichment mineralization. Nevertheless, it is likely that the geology of the supergene enrichment zone at QB can provide clues about the underlying hypogene lithologies, mineralization, and hydrothermal alteration. This project is investigating the geology intersected by nine drill cores from a NS cross-section at 19,600 m E through the QB open pit in order to understand the nature of hypogene mineralization, hydrothermal alteration, and the principle host lithologies at QB. Pre-existing major oxide lithogeochemical data (n = 7540), and new petrological and lithogeochemical data (n = 100) were examined to provide insight into: (1) the igneous and hydrothermal processes that produced the host rocks; (2) the nature of hydrothermal alteration and how host rock composition controls the resulting mineral assemblages; and (3) how weathering processes have affected hypogene rocks. Three principle lithologies exist within the QB open pit. They consist of diorite that was intruded by quartz monzonite, and a suite of later, irregular plagioclase porphyry dykes associated with mineralization. The petrography of hypogene samples indicates the presence of minor propylitic alteration (mostly in diorite), weak to moderate potassic alteration overprinted by strong phyllic alteration in quartz monzonite, and potassic alteration in plagioclase porphyry. Phyllic alteration consists of quartz and sericite, the latter occurring incipiently replacing both igneous feldspar and feldspar formed during potassic alteration, within veins with quartz, and as polycrystalline masses replacing the igneous matrix. Intense phyllic alteration typically obliterates original textures in quartz monzonite. Potassically altered plagioclase porphyry units generally contain plagioclase altered to potassium feldspar. Pearce element ratio analysis was undertaken using lithogeochemical data from pre-existing supergene samples. These data indicate that most historic samples are phyllically altered and that phyllic alteration at QB exhibits a range of quartz/ muscovite ratios (from 1 to 3) that exhibit spatial patterns. Within individual phyllic alteration zones, quartz/muscovite ratios gradually increase from 1 in the southeast to 3 in the northwest. These zones are rooted along muscovite-rich northeast-southwest-trending faults from which phyllic alteration flares upward and to the southeast.


This study is conducted in the context of developmental learning in embodied agents who have multiple data sources (sensors) at their disposal. We describe an online learning method that simultaneously discovers "meaningful" concepts in the associated processing streams, extending methods such as PCA, SOM or sparse coding to the multimodal case. In addition to the avoidance of redundancies in the concepts derived from single modalities, we claim that "meaningful" concepts are those who have statistical relations across modalities. This is a reasonable claim because measurements by different sensors often have common cause in the external world and therefore carry correlated information. To capture such cross-modal relations while avoiding redundancy of concepts, we propose a set of interacting self-organization processes which are modulated by local predictability. To validate the fundamental applicability of the method, we conduct a plausible simulation experiment with synthetic data and find that those concepts which are predictable from other modalities successively "grow", i.e., become over-represented, whereas concepts that are not predictable become systematically under-represented. We conclude the article by a discussion of applicability in real-world robotics scenarios.


Free-living tadpoles of the American Bullfrog, Rana catesbeiana, an introduced species, were found in eastern Boyacá. The introduction of this alien into the Amazon Basin could cause dramatic changes in the frog fauna there.


The title compound, [RuH(C6H8BN4)(C21H21P)2(CO)], possesses two trans-disposed tri-p-tolylphosphines in axial positions and the remaining ligands in equatorial positions. The overall geometry of the RuII ion is a distorted octahedral structure. The P—Ru—P axis deviates from linearity by about 13°. This distortion arises mainly from the steric congestion between the bulky phosphine moieties and the tetrahedral dihydrobis(pyrazol-1-yl)borate ligands.


Objectives: We hypothesized congenital heart disease (CHD) patients with respiratory ciliary motion (CM) defects may have increased prevalence of brain abnormalities. Background: We recently showed CHD patients have a high prevalence of airway motile cilia dysfunction. In the brain, motile cilia in the ependyma mediate cerebrospinal fluid (CSF) flow required for neuronal cell migration/neurogenesis. Cilia are also found in the choroid plexus and are required for maintenance of neural progenitors. CHD patients with airway motile ciliary dysfunction may be at increased risk of neurocognitive abnormalities. Methods and Results: 40 neonates with complex CHD underwent preoperative cranial US, volumetric MRI and respiratory ciliary motion (CM) assessment with high-speed videomicroscopy of nasal biopsies. CM was scored on a scale of 1 to 4, with 1 indicating normal CM, ranging to 4 for highly abnormal CM. Multivariate logistical regression of brain measurements with CM scores revealed significant correlation between respiratory CM defects and brain abnormalities (right panel, p Conclusions: Airway ciliary dysfunction is associated with structural brain abnormalities in neonates with complex CHD including: (1) subtle brain dysplasia in the olfactory bulb/hippocampus; (2) choroid plexus abnormalities and (3) increased extra-axial CSF fluid. These clinical translational studies suggest a potential unifying role for the cilia in contributing to both structural heart disease and brain abnormalities in CHD patients.


Purpose. Development of a mathematical model of transition processes for a detailed study of the harmonic components of the voltage and current of the IG as part of autonomous generator sets at high saturation of the magnetic system. Result. The article presents an analysis of the steady-state mode of a self-excited induction generator based on a mathematical model in a three-phase coordinate system, which makes it possible to take into account the influence on the dynamic characteristics of an asynchronous generator of such physical phenomena as the nonlinearity of the magnetization curve, the phenomenon of hysteresis and eddy currents. The article simulates and evaluates the influence of the value of the connected load on the quality of the generator output voltage. The Fast Fourier transform algorithm is used to analyze the harmonic components of the voltage and current of an induction generator in a steady state. The change in the harmonic coefficient and its compliance with the boundary permissible values are analyzed. The results of experimental studies of an asynchronous generator in an autonomous mode of operation were obtained, and the adequacy of the proposed mathematical model was assessed. Practical value. The carried out theoretical studies of the capacitive self-excitation of IM machines have created a good basis for solving issues related to the practical use of autonomous sources based on an asynchronous generator.


Abstract Distribution of Inopus rubriceps Macquart was studied in plots subjected to low, medium, and high stocking rates. Larval and pupal densities and adult activity were greatest over areas of long pastures resulting from selective grazing. Larval numbers and total root weights were positively correlated. Reasons for soldier fly aggregation in these areas are discussed.


In this paper, a power assisted system for an overhead crane is presented. This system is realized by measuring the swing angle of a crane and moving the trolley and girder in the desired direction. Therefore, operators can move a heavy object freely using only slight force. In this paper, two kinds of controllers are proposed. One is a PD controller that emulates the dynamics of object with damping and it moves the object in proportional velocity to the operating force in steady-state. Another is a PID controller that maintains the velocity of object continuously after operators cease the application of their force. Its dynamics, damping characteristics, steady-state and admissible condition of controller gain are discussed in regard to the respective controllers. This system is applied to an experimental overhead crane in the laboratory, and the effect of energy saved by the power assist is shown by measuring the heart rate of operator.


The constant increase of the computational power will allow in a close future to frequently perform Large-Eddy Simulation (LES) of complex flows with an industrial rendering (time and cost). Consequently, numbers of LES methodologies are explored and applied for high Reynolds number flows in complex geometries. Among these configurations, flows over bluff bodies are related to many aerodynamic applications and represent ones of the most current test cases for the numerical validation. As it is typical for bluff body wakes, drag prediction and its control are among the main objectives of aerodynamics studies. In the present work, we propose a high-order LES methodology based on spectral approximations to perform turbulent flow over complex geometries. The LES-methodology is based on the Spectral Vanishing Viscosity (SVV) stabilization method, as developed in [7]. Basically, the energy cascade from the low frequencies to the higher ones is taken into account as an increased diffusion in the higher frequency range. However, an appropriate treatment of the near wall region with the SVV (SVV-NW) appears here quite necessary. Two ERCFOTAC test cases have been investigated: the classical square cylinder and the more complex Ahmed body. The flow over the square cylinder at Re=21400, [4], has been first addressed and has shown in particular the efficiency of the SVV-NW correction to describe the turbulent boundary layers around bluff bodies. Then, the more tricky Ahmed body test case [1] which is now considered as a reference car model for the study of flows around road vehicles has been studied for a slant angle of 25 (value for which the flow partially separates on the slant) and a Reynolds number of 768000. The flow that develops in this case is very complex, i.e., fully three-dimensional, unsteady, with separations and very thin turbulent boundary layers. Consequently, only few the numerical works agree with recent experimental results [3]. Moreover, as it clearly appeared during the


Abstract With the changing industrial landscape of the country, new working class areas have come into being and old ones are expanding. In the new areas, adaptability to this culture depends on the extent and strength of the workers' link with rural areas. The characteristics of the Textile Workers revolve around Social Composition, Sex Composition, Emergence of Tribal Labour, Low Level of Literacy, Heterogeneity of Working Class, High Rate of Absenteeism, Labour Turnover and Migratory Character. An anthropological attempt has been made in the present study to analyse the ethnographic profile of the textile workers of Uttar Pradesh. A total number of 463 adult workers working in different sectors in seventeen different factories were interviewed, The religious and ritualistic analysis of the observance of actions or procedures in a set and ceremonial way of the Hindu and Muslim textile workers of Uttar Pradesh, reflects that the religious rites and rituals of Hindu workers were more complex than Muslim workers and they believe in the concept of actions (karma) and earn merit (punya) for themselves, their families, their ancestors, their future and society in general.


The peppered shiner, Notropisperpallidus Hubbs and Black, is a small, silvery, upland stream fish foundonly in outhwesternArkansasand eastern Oklahoma.This fish species was studied from 1999-2001 to determineits distribution, habitat, iiidconservationstatus. A total of 81 collectionswas madeduring the 2-yearstudy;however, only 17 specimenswere collected. The presentdistributionof the peppered shinerin ArkansasandOklahomais describedas wellas theconservationstatus of thiscyprinid in bothstates.


This paper provides the initial framework for exploring the effects of CEO's cognitive orientations on innovation adoption and assimilation in organizations. At the innovation adoption stage, I propose that abstract and concrete cognition orientations of the decision makers will determine which sources of innovation are exploited based on their proximity to the adopting entity. At the assimilation stage this cognitive pattern will determine whether the innovation is emulated in its original form, or adapted to ensure a fit with the adopting entity. To further understand the extent of CEO impact on innovation decisions, I propose CEO power as a moderating mechanism.


This paper is a study of derivations on unbounded operator algebras in connection with those in operator algebras. In particular we study spatiality of derivations in several situations. We give the characterization of derivations on general *-algebras by using positive linear functionals. We also show that a derivation with some range-property on a left EW#-algebra induced by an unbounded Hilbert algebra is strongly implemented by an operator which belongs to an algebra of measurable operators.


SUMMARY Data on turbidity and the factors influencing it, such as wind and substratum, were collected from eight representative estuaries along the Natal Coast. The results showed that Natal Estuaries can be divided into one of four groups, according to the turbidity regime present in the system, as either Clear ( 80 NTU). The influence of the tidal cycle on turbidity, salinity and temperature was also investigated. It was found that tidal action often creates gradients within a system. Turbidity gradients were more frequent in occurrence than either salinity or temperature gradients.


Awareness raising and forming the habit of waste separation for students in general and those with intellectual disability are a way to influence right from the start to help children adapt well to the living environment and interact effectively in the social environment. Guidance on how to organize educational activities regarding waste separation was built to meet the goal of training waste separation skills for students with intellectual disability at special education institutions. The process of experimentation and survey shows that the material is really good quality and suitable for children with intellectual disabilities. This, thereby, affirms that students with intellectual disabilities will have a change in their understanding of waste separation if they have a chance to learn about and practise separating waste. They will become accustomed to as well as develop this habit on a daily basis, thus enabling them to contribute their part to the overall conservation of the environment.


About the Contributors Table of Cases Table of Legislation 1. Collectivity,Management of Estates and the Pari Passu Rule in Winding-Up Michael Bridge 2. Transactions at an Undervalue John Armour 3. Transactions Defrauding Creditors John Armour 4. Preferences Adrian Walters 5. Late Floating Charges Howard Bennett 6. Registration of Company Charges Howard Bennett 7. Avoidance of Transactions as a 'Fraud on Creditors' at Common Law John Armour 8. Void Dispositions in Compulsory Winding-Up Adrian Walters 9. Restitution for Vulnerable Transactions Simone Degeling 10. Cross-border Insolvency and Vulnerable Transactions Sandra Frisby Appendix: Statutory Provisions Index


An apparently new approach to the solution of EHD film thickness is presented for line contact. This approach can readily accept non-Newtonian response as it is not based upon the Reynolds equation. Thermal effects and sliding may also be incorporated, although for large departure from Newtonian the pressure criterion should be reexamined


amend privatization. This lack of firm laws proves that there must be legislative control over the privatization process. She does not mention, however, that legislation cannot be effective if the constitution remains socialist. She also fails to mention that existing restrictions suffocate privatization, and that bureaucrats often stymie state policy in their daily practices. Qasim proposes a strategy to stimulate exports that includes lifting administrative restrictions that hinder the growth of exports, restructuring tariff regulations, reducing exchange and fee taxes, and increasing tax incentives to attract more local and foreign investments. She has an excessive trust in privatization and assigns an exaggerated role to the banks, perhaps as a result of her own experience in banking. Despite its limitations, Qasim's study is one of the few references on privatization in Egypt.


The results of sound propagation through the warm mesoscale eddy in the region of Kuroshio at the Northwest Pacific are presented. The eddy core lies at point about 39° N, 149° E. Horizontal size of eddy was about 350 km, vertical size was more than 600 m. Continuous acoustic signals at the frequencies 232 Hz and 696 Hz were emitted by the sources towed at the depth of 100 m. Signals were received using a drifting system fitted with hydrophones. The results of experimental researches of sound propagation along the traces crossing subarctic frontal zones separating the cold subarctic and warm subtropical waters are submitted too. Reception system was located at a shelf zone near a peninsula Kamchatka at the depth about of 100 m. These traces extended to the distance 2100 km. It is shown that eddies and frontal zones result to the changes of acoustic signal levels. The experimental results were compared with the calculations of acoustic field.


In this paper, a characterization of orthonormal multilevel wavelet families in Sobolev space over a local fields of positive characteristic (Hs(K)) is established. Finally an example is presented.


Abstract Recent significant changes in technology such as Artificial Intelligence (AI) and big data analysis have a wide impact in many areas of human societies, not least in education. Advances in efficiency of new technologies, with impacts in renewable energy and transport affected by environmental concerns and climate change mitigation, demand a reassessment and adjustment of the industrial structure of the economy. Technological advances enhancing creativity and analytical skills mean people must learn and adapt to a fast-changing economic environment. This paper present some key changes in Australian educational areas in recent years that are important and relevant to the subject of education innovation and philosophy to achieve outcomes in training and sustainable economic development, as anticipated by the community and government. Education courses and curricula in many countries have been transformed by technological advance. It is the swift incorporation of new technologies that best prepares students for the dynamics of economic and social change. Even though technological responsiveness is not a new phenomenon, it is established that the teaching methods found to be most successful include complementary and supplemental courses producing multi-skilled and creative graduates. These courses are delivered with significant emphasis upon self-development skills and are less focused upon traditional content. A move toward horizontal focus and a student-centric balance is the current trend, displacing vertical over-specialisation of learning. Yet, the central role of educator is seen as still appropriate and necessary where the aim is to equip graduates with creative and adaptive skills.


To a large extent, an audio fade is distinctly acknowledged as a strict increase (fade-up) or decrease (fade-down) of the volume of an audio content. In this broad context, the widely used fade-in and fade-out sound effects, applied to receive smooth transitions from and down to silence, respectively, appear to be restrictive. Taking into account the increasing demand for multimedia techniques adapted for real-time computing, the present investigation advances straightforward procedures intended for customizing the audio fade-up and fade-down profiles, having at hand well-proven techniques of shaping the fade-in and fade-out audio effects, suitable for fast computing.


Significance Metastable high-pressure materials often possess outstanding properties. However, the stabilization of metastable high-pressure materials usually is challenging due to the very low kinetic barrier for the transformation back to ambient phases. Wurtzite boron nitride (w-BN) is a metastable high-pressure polymorph of BN, which can only be fabricated as micrometer-size powders by the shock compression of hexagonal BN. Here, we fabricate millimeter-size w-BN bulk crystals and reveal an unprecedented stabilization mechanism for w-BN. We find that the metastable high-pressure phase can be stabilized by 3D networks of planar defects. Our findings unambiguously demonstrate the retarding effect of crystal defects on the phase transformations of metastable materials. Wurtzite boron nitride (w-BN) is a metastable superhard material that is a high-pressure polymorph of BN. Clarifying how the metastable high-pressure material can be stabilized at atmospheric pressure is a challenging issue of fundamental scientific importance and promising technological value. Here, we fabricate millimeter-size w-BN bulk crystals via the hexagonal-to-wurtzite phase transformation at high pressure and high temperature. By combining transmission electron microscopy and ab initio molecular dynamics simulations, we reveal a stabilization mechanism for w-BN, i.e., the metastable high-pressure phase can be stabilized by 3D networks of planar defects which are constructed by a high density of intersecting (0001) stacking faults and {101¯0} inversion domain boundaries. The 3D networks of planar defects segment the w-BN bulk crystal into numerous nanometer-size prismatic domains with the reverse crystallographic polarities. Our findings unambiguously demonstrate the retarding effect of crystal defects on the phase transformations of metastable materials, which is in contrast to the common knowledge that the crystal defects in materials will facilitate the occurrence of phase transformations.


Wayside Teaching is an education that the teacher teaches students outside the classroom. Based on the discussion of the connotation, features and functions of Wayside Teaching, this study uses the methods of questionnaire survey and interview, takes 288 students and 74 teachers from Universities in Xinxiang city as the research object, analyzes and summarizes the current application of Wayside Teaching in college teaching and puts forward the corresponding countermeasure aiming at the inadequate application of teaching.


Abstract:  Juvenile xanthogranuloma is a benign histiocytic skin disorder encountered primarily in infancy and childhood. Approximately 0.4% of cases exhibit ocular manifestations, which can result in glaucoma and blindness. We present a case of a 7‐month‐old male with unilateral glaucoma associated with Juvenile xanthogranuloma, and emphasize the importance of an ocular screening in patients with Juvenile xanthogranuloma, especially those with periocular lesions.


Microstickies present a formidable challenge for papermakers. Many strategies have been explored to control them. Enzyme treatment is a promising technology, but the mechanism of its action has not been determined, thus inhibiting further application of this new technology. This study investigated characteristics and size distributions
of microstickies treated by esterase-cellulase mixtures. Determination of particle size and number was accomplished using a modified flow cytometer, which combined streaming capillary flow, laser-based particle size analysis and fluorescent dye tracing. The results showed that treatment of samples with enzyme mixtures induced size reduction of the larger microstickies. This effect was most dramatic for 1:1 ratios of esterase to cellulase. The treated particles were more stable than untreated ones. The smaller microstickies treated with some ratios of esterase and cellulase tended to aggregate over time. The behaviors of microstickies treated by enzyme mixtures were
only slightly affected by temperature and shearing action. The surface physicochemical characteristics of these particles indicated that changes of these basic properties affected the whole whitewater system and resulted in a new equilibrium among all the particles.


Complex plasmas - plasmas containing macroscopic particles (e.g. colloidal dusts), electrons, ions, and neutrals are open systems. Therefore parameters of the macroscopic particles such as particle charge appear as a function of not only their internal characteristics (e.g. size, shape, material, etc.), but also as a function of external plasma conditions (e.g. plasma density, temperature, etc). Our knowledge in the particle charge is the foundation of our understanding of the self-organized structure, as well as phase transitions observed in complex plasma.


Objective To observe the antihypertisive effects of single use of extended release nifedipine tablets or enalapril tablets and combination of these two drugs.Methods Forty-five patients with hypertension crisis were randomly divided into three groups(15 patients in each group):control group 1,control group 2,and treatment group.Patients in control group 1 and control group 2 were given only extended release nifedipine tablets and enalapril tablets,respectively.Patients in the treatment group received these two drugs simultaneously.Result The antihypertisive effects of combination of two drugs in the treatment group were better than control group 1 and control group 2(P 0.05).Conclusion Sublingual extended release nifedipine tablets and enalapril tablets can get ideal antihypertensive effects in time for patients with hypertension crisis,and it is a simple,convenient,rapid,effective,and safe treatment method for patients with hypertension crisis


Fenfluramine (Ponderax - Selpharm) is a new appetite depressant, developed in France and introduced in Britain late in 1963. It is chemically related to amphetamine: its main distinguishing feature is a trifluoromethyl group attached to the benzene ring. The makers state that the drug does not stimulate the central nervous system, that it is not habit forming, and that it can be used by diabetics and hypertensive patients. They also state that it not only reduces the appetite, but also makes possible 'prolonged treatment resulting in a true re-education of the appetite - which will persist after . . . ending . . . treatment'.


It is indicated that permanent magnets are present in organisms and nanostructures. Based on the solution of Maxwell's equations, a mathematical model of the structure of the electromagnetic field of a permanent magnet and a mathematical model of the distribution of magnetic dipoles in the body of a permanent magnet are built.


The paper is concerned with the capillary instability of a liquid thread surrounded by another immiscible liquid. We study the occurrence of the dominant mode of perturbation for different combinations of Newtonian and viscoelastic fluids. When a viscoelastic fluid is present, in the limit of small deformations, the dispersion relation is obtained via a Maxwell type approximation of the viscosity curve which can be directly incorporated into an existing model of thread instability. Measurements of the fastest-growing mode are then performed and compared with theoretical predictions. A satisfactory agreement between the theory and experiment is found in terms of the wavenumber of the fastest-growing mode.The paper is concerned with the capillary instability of a liquid thread surrounded by another immiscible liquid. We study the occurrence of the dominant mode of perturbation for different combinations of Newtonian and viscoelastic fluids. When a viscoelastic fluid is present, in the limit of small deformations, the dispersion relation is obtained via a Maxwell type approximation of the viscosity curve which can be directly incorporated into an existing model of thread instability. Measurements of the fastest-growing mode are then performed and compared with theoretical predictions. A satisfactory agreement between the theory and experiment is found in terms of the wavenumber of the fastest-growing mode.


Leading edge and trailing edge flap deflection effect on high left and lateral control characteristics of semispan variable sweep wing and tail surfaces


This master thesis compares the logistic chain of operations and maintenance versus drilling and well and finds how drilling and well affect this chain with regards to risk on crane and lifting operations. Research has been done through accident/incident analysis, statistic, observations and interviews. An influence diagram for frequency is made, to better understanding the risk influencing factors (RIF) that affects a crane and lifting operation. The influence diagram is based on operational-, organisational-, and authority- and customer related risk influencing factors. These factors describe general causes and actors influencing the risk for frequency or consequence of a crane- and lifting operation accident. The risk influencing factors is modelled in a Bayesian Network (BN) to see how they affect the severity of incidents. To make the BN the program GenIE is used, this is a very useful program to model risk, but can be a bit complicated with regards to many influencing factors and many levels of the factor. From investigation of the logistic chain, incidents/accidents and statistics there was found: Underlying causes: Simulation and practice 38.5% Operators maintenance organisation 14% Coordination and planning 24.6% Operations, procedures and support 23% Direct causes: Human factors 35% Operational working conditions 29% Compliance 27% Physical/environmentally conditions 9 Incident: Green 96,93% Yellow 1,43% Red 1,64 When situations are at high risk (red), precautions must be taken straight away. The analysis shows that it will be most efficient to improve coordination and planning; the underlying case is reflected in all the direct causes and will affect all of them in a positive way. Some measurements will affect coordination and planning easily. A lot of misunderstandings could have been avoided if everyone had been using the same technical system, SAP, for ordering and planning. To achieve this goal everyone must learn how to use the system, and use the same part of it. A group of planners from each unit should meet once a day and work together to make one plan and inform each other about changes. For the supply vessel and installation it would have been much easier if every documentation and certification were online, this could make their planning process much easier. Then plans of where the goods should be placed could be done before the vessel enters at the supply base and the installation would have had time to prepare better for reception of the supply vessel. This should be quite easy to implement since all goods should already have a serial number in SAP: The milling machine at the installations would also make things much easier, because then not so many containers would need to be shipped to the installations and space and money would be saved.


This paper introduces the humanized teaching reform and the practice in physical chemistry course in the way of classroom teaching,teaching management and cultivation of students' ability.


A simple mathematical model for predicting the vortex‐excited resonant response of two cylinders in line with the wind direction is presented. For the model, a modified van der Pol equation is employed to account for the effect of fluctuating lift force on the cylinder, and this equation is coupled with the equation for the oscillatory motion of the cylinder. The governing equations are nonlinear in nature, and the solutions of these equations are assumed to be in the form of sinusoidal functions. Results obtained are in good agreement with the experimental data.


House removing is a key and difficult issue in land requisition and resettlement in Beijing-Shijiazhuang Emergency Water Supply Project,the work needs various sectors to coordinate to complete.Tangxian County relies on local government,through publicity and standardizing work procedures,by means of evaluation and signing agreements,to compensate reasonably for dismantling house,making the removing work rapidly progress.


n the past decade of educational reform, there has been one astounding accomplishment: The federal and state governments and the private sector have recommended and adopted policies to advance the visual and performing arts as essential to a comprehensive education. The goals created by the president and the governors of all fifty states for American education now include the arts. Goals 2000 and other legislation have provided funding for arts education. The National Assessment for Educational Progress has adopted a policy to assess the arts each decade. Those exemplary policies and resources for arts education are embracing an educational direction aimed to graduate students who are artistically literate. However, several studies have revealed that there are serious flaws in some arts education policies. In this article I examine several of those. The policies discussed herein are not a comprehensive listing nor are the discussions exhaustive. For example, education policies of public arts agencies and organizations, including the National Endowment for the Arts, have hardly been included (see Gee 1999a, 1999b).


Photolysis of gas-phase water has been carried out on NaOH-coated Rh/TiO2 and Pd/TiO2 catalysts. Hydrogen and oxygen were simultaneously produced on both catalysts and the stoichiometric composition (H2/O2= 2) was obtained for most of the catalysts. The rate of water photolysis strongly depended upon the amount of NaOH loaded and the pressure of water vapour. The photolysis rate on the Rh/TiO2 catalyst was maximized at 15 wt % of NaOH coating and at ca. 2 Torr of water-vapour pressure. The photocatalytic activity depended upon the kind of metal deposited as well as the source of TiO2. Rh was more active but Pd was less active than Pt, which was tested previously. The highest formal quantum yield was ca. 29% when the Rh/TiO2 catalyst was used. The dependences of the photolysis rate on light intensity, wavelength and thermal back reaction rate have also been studied.


After infection of tetracycline producing strains of S. uureofaciens with actinophages ~1/6 and B 1 some phage resistant colonies were obtained in each experiment. These colonies expressed a new restriction-modification (RM) system of type II, which was different from the common RM system (SauLPI) of these strains recognizing the sequence GCCGGC. This new RM system was not detected before in parental strains. The new endonuclease was purified from a phage resistant strain of S. aureofaciens B96, using two step column chromatography to the grade without non-specific nucleolytic activity. SauLPI endonuclease recognized and cleaved the palindromic hexanucleotide sequence S-C/TCGAG-3', thus it was a true isoschizomer of XhoI. KeJw0rd.c: Streptomycetes; Phage infection; Restriction endonuclease: XhoI isoschizomer; SauLpI


Authors have long known of the need for "cues" to assess the competence and training of providers of credence services. In the case of health care providers such as eye care professionals, one such cue is whether the eye care professional is "board certified." This study of 500 consumers who had had an eye exam either from an optometrist or an ophthalmologist examines four questions: what factors are important to a consumer seeking an eye-care provider, what is communicated by an eye-care provider's claim of being board certified, whether there are differences in perception between board certification as applied to an optometrist and an ophthalmologist, and whether there are differences in the perceptions of optometrists who are board certified compared to those who are not board certified. The results show that board certification is an important cue for consumers in assessing the competence and expertise of optometrists and that board certification can be used to distinguish between an optometrist and an ophthalmologist. The results also show that optometrists who are board certified as seen as better trained and more competent than optometrists who are not board certified.


Different from the conclusions of financial assets with high risk bringing high earnings studied by traditional theories,an analysis is made by using GARCH-M model on risk and earnings of classified hedge fund index,discovering that earnings performance of some classified hedge fund index illustrates a high risk versus a low earning.The reason for high leverage and complexity of derivatives has made more sophisticated earning and risk situation for hedge fund.It can't be readily believed that hedge fund will offer higher earning in the higher risk profile.The research made by foreign scholars discovers that the reason for a high dismissal rate of hedge fund is failure of investment with a general duration of three to five years.This reminds the investors of more consideration of risk endeavor.


Abstract: The objective of this classroom action research is to investigate the improvement of the quality of social studies – geography learning through silent picture media. The subjects of this research were 20 male and 14 female Fourth grade students  SDN Rampal Celaket I Malang.  This research found that there was improvement of the quality of social studies – geography learning through silent picture media.


Presented at the Minnesota District Spring WELS Pastoral Conference at Trego, WI on April 10, 2002. Contains a preaching resource section which includes a Bible study called "The Art of Listening to a Sermon", a list of sermon books, periodicals, tapes, videos,and web sites, five dramas and reader's theater selections, and five sermons.


This paper describes the design and characteristics of a three dimensional actuator for an optical readout head. In order to obtain enough servo gain, it is necessary to reduce the size and weight of the moving parts. Instead of the conventional galvano mirror, this actuator drives the objective lens, which is suspended in the collimated laser beam, towards three directions, vertical, radial and tangential, without tilting. The major advantages of this unique three dimensional actuator lie in reducing a cost of the objective lens and the number of the adjusting points.


Restaurants have relied on 'word of mouth' communication (Longart, 2010) and is rewarding customers not only for repeated business but also for referring family and friends. However, Indian restaurants have been laggard in embracing paper coupons. Nevertheless, recently with the maturing of mobile technology and smartphones, which are getting ubiquitous, a lot has changed. Restaurants in India have adopted mobile couponing leaving paper coupons, which were never really used in India, as they were in the west where newspapers were filled with coupons and said to have the highest redemption rates (Teel et al., 1980). The present research focuses on mobile coupons various determinants and their impact on purchase in context with Indian quick-service restaurants (QSR). The findings suggests that customers have found mobile coupons helpful in saving money. Hedonic and utilitarian attitude have a moderating effect on the customers propensity to use mobile coupons to make a purchase.


A general, mild, and convenient method has been developed for the synthesis of various N-substituted and N, N-disubstituted sulfonamides, as a class of sulfa drugs, from the corresponding amines and p-toluene sulfonyl chloride in the presence of readily available crosslinked poly(4-vinylpyridine) as a catalyst, base or polymeric substrates. The use of polymeric catalyst simplifies routine sulfonylation of amines because it eliminates the traditional purification. The polymer can be removed quantitatively and it can be regenerated and reused for several cycles without losing its activity. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012


Today's semiconductors consist of up to forty structured layers which make up the electric circuit. Since the market demands more powerful chips at minimal cost, the structure size is decreased with every technology node. The smaller the features become, the more sensitive is the functional effciency of the chip with respect to placement errors. One crucial component for placement errors is the mask which can be viewed as a blueprint of the layer's structures. Hence, placement accuracy requirements for masks are also tightening rapidly. These days, mask shops strive for improving their positioning performance. However, more and more effort is required which will increase the costs for masks. Therefore, the transfer of mask placement errors onto the wafer is analyzed in order to check the guidelines which are used for deriving placement error specifications. In the first section of this paper the basic concepts for measuring placement errors are provided. Then, a method is proposed which is able to characterize the transfer of placement errors from mask to wafer. This is followed by two sections giving a thorough statistical analysis of this method. In the fifth section, the connection to placement accuracy specifications on mask and wafer is established. Finally, the method is applied to a set of test masks provided by AMTC and printed by AMD.


This article provides an introduction to the burgeoning academic literature on Bayesian Vector Autoregressions, benchmark models for applied macroeconomic research. We first explain Bayes' theorem and the derivation of the closed-form solution for the posterior distribution of the parameters of the model given data. We further consider parameter shrinkage, a distinguishing feature of the prior distributions commonly employed in the analysis of large datasets, as well as an alternative way of specifying the prior distribution using dummy observations. Finally, we describe the mechanisms that enable feasible computations for these linear models that efficiently extract the information content of many variables for economic forecasting and other applications.


In this paper we describe the use of single-mode optical fibres to deliver moderate-power, but very high beam quality Nd:YAG light for precision machining, at peak powers of 300 W in 0.1 ms pulses. An example application is demonstrated: the cutting of 0.05 and 0.2 mm thick stainless steel sheet with kerf widths and feature sizes as small as 30 μm.In this paper we describe the use of single-mode optical fibres to deliver moderate-power, but very high beam quality Nd:YAG light for precision machining, at peak powers of 300 W in 0.1 ms pulses. An example application is demonstrated: the cutting of 0.05 and 0.2 mm thick stainless steel sheet with kerf widths and feature sizes as small as 30 μm.


1. A device for reducing the rapid absorption of alcohol-induced oral dosage forms for sustained release opioid dose which, being an osmotic dosage form, is characterized by including a space formed at least in part, by a semipermeable membrane compartment through which releases the opioid sustained by the presence of an aqueous alcohol.


In view of the unstable phenomenon of the visual system of the AGV in the automatic system, the paper adopts the MEMS gyroscope MPU6050 to collect the status of the visual holder. We can guarantee the stability of the holder, obtain clear pictures and improve the operating validity of the vision-based guided AGV by controlling the brushless motor through the Arduino single chip microcomputer program.


In this paper, problems that handicapped persons might have regarding accessibility to vehicles, etc. are pointed out. For example, many parking stalls have not got aisles for the transfer from an automobile to a wheelchair. If a van is used even more room is required between parked vehicles to allow the handicapped persons to enter or leave the hydraulic platform. It is also very important that road surfaces are even. If not the route of travel may be dangerous and even cause handicapped persons to be thrown from their chairs. Gratings and manhole covers are potential dangers. Inclined surfaces affect the mobility of people who are blind, deaf or who are in wheelchairs. Traffic light control boxes and signs which are mounted at head height above sidewalks are dangerous for pedestrians and especially blind persons. Special efforts have also to be made concerning accessible transport and adaptation of buses, trains, etc.