The transcription factor FOXN1 is essential for fetal thymic epithelial cell (TEC) differentiation and proliferation. In the postnatal thymus, Foxn1 levels vary widely between different TEC subsets, from low or undetectable in putative TEC progenitors to highest in the most differentiated TEC subsets. Correct Foxn1 expression is also required to maintain the postnatal microenvironment, as premature down-regulation of Foxn1 causes a rapid involution-like phenotype, while transgenic over-expression can cause thymic hyperplasia and/or delayed involution. In the current study, we investigated a K5.Foxn1 transgene that drives Foxn1 over-expression in TECs, but does not cause hyperplasia, nor does it delay or prevent aging-related involution. Similarly, this transgene cannot rescue thymus size in Foxn1lacZ/lacZ mice that undergo premature involution due to reduced Foxn1 levels. However, K5.Foxn1 transgenics do maintain TEC differentiation and cortico-medullary organization with aging both alone and in hypomorphic Foxn1lacZ/lacZ mice. Analysis of candidate TEC markers showed co-expression of progenitor and differentiation markers as well as increased proliferation in Plet-1+ TECs associated with Foxn1 expression. These results demonstrate that the functions of FOXN1 in promoting TEC proliferation and differentiation are separable and context-dependent, and suggest that modulating Foxn1 levels can regulate the balance of proliferation and differentiation in TEC progenitors.


Containing 29 lawsuit cases,with occasional detailed instruction on the know-how of legal document writing,this manual was a testimony to the practice of legal system in local society in late Qing and early Republican Jiangxi.


The present invention, user terminal, the infection by blocking the user access to web pages containing the infection of the web page search using a search engine to group the web pages that contain the malware on the web site management method to provide a way to prevent exposure. Disseminated infection site management method using a search engine in accordance with one embodiment of the invention To this end, the steps of determining whether (a) is analyzed to contain malicious code, the currently accessed web site; (B) registering the website with the infection spreading site if included for malware is determined that the currently connected website; And (c) if the Web site search results with a search engine that includes the registered web site by the malware distributed sites includes a step to block the user's access to the website. Thereby, the advantage of being able to prevent by blocking user access to a Web page that contains the malicious code at the Web page search using a search engine to categorize web pages containing malicious code, the user terminal is not exposed to malicious code there is. Malware, web sites, search engines


The present invention particularly relates to a method (100) of repairing an inner surface (12) is broken (11) of the fan housing (10) is provided. The method (100) comprises (13) a reinforcing member connected to the fan housing step (102) (10), an outer surface of the reinforcing member (13) is connected to the fan housing (10) (14 a), the damage (11) opposite.


The recent literature identified that certain types of smooth floors and flooring materials showed good slip-resistance performance under moderately contaminated situations such as water wet and soapsuds-covered conditions. However, topographic structures of such flat floor/walkway surfaces are significantly changed by wear and tear developments with continuous ambulation. A number of reasons seem to be involved in flooring wear developments, but such changes may result in substantial losses of slip resistance (or traction) functions. Even though the importance of this issue is wide, it is scarce to find any systematic investigations on tribophysical characteristics of smooth floors (<10 µm in Ra roughness) and their wear impacts on traction performance. Moreover, it is difficult to find studies on wear progress of floors and its impacts on pedestrian fall safety assessments. This study focuses on exploring wear activities of smooth resilient floors and disclosing wear consequences on traction properties. To measure slip-resistance features and investigate wear advances of smooth resilient floors, dynamic friction tests were carried out amongst purposely arranged 4 flat specimens (polymethyl methacrylate: PMMA) and 3 shoes. Wear formations and progressions of the PMMA surfaces were methodically evaluated by observing surface profiles during the tests. The test outcomes evidently presented that initial surface features of the PMMA specimens were significantly modified by primary-, secondary-, and shared-wear mechanisms and significantly influenced traction performance. This study may have design applications for the safety enhancements of smooth floors/footpaths to preclude pedestrian fall incidents.


Abstract To estimate residency and population sizes, endemic fishes were marked and released during October 1998 at confluence of Colorado River and Havasu Creek (Grand Canyon National Park, Coconino County, Arizona). Ripe Catostomus (Pantosteus) discobolus females and newly hatched fry confirmed late season (i.e., early October) spawning by this species. Reproduction by other catostomids was inferred through physical examination of adult C. latipinnis and by capture of a possible Xyrauchen texanus larva. The latter is an endangered species not considered a constituent member of the endemic Grand Canyon fish community; its potential presence in Grand Canyon will influence adaptive management of endemic and introduced fishes. Results of ANCOVAs (with fishing effort as covariate) indicated numbers of aggregating C. latipinnis were significantly associated with flows in Havasu Creek but not those in the mainstem Colorado River. The ecology of big-river endemic fishes in Grand Canyon is clearly linked to tributary outflows, and environmental cues which elicit spawning of native fishes are discussed.


PROBLEM TO BE SOLVED: To provide a beater for a drum capable of quickly and reliably adjusting a weight of a beater head only by manual labor, regardless of a simple structure with the minimized number of components, and a foot pedal device for a drum.SOLUTION: A drum beater (200) for use in performance of a drum includes: a beater head (2) for beating the drum; a beater rod (3) to which the beater head (2) is attached; a holding member (210) axially movably attached to the beater rod (3) only by manual labor without using any tool; a spring (220) for biasing the holding member (210) toward the beater head (2); and a weight member (230) held by bias force of the spring (220) while being clamped between the holding member (210) and the beater head (2).SELECTED DRAWING: Figure 3


ABSTRACT This article provides updates on the evolution of Instructional Insights as well as introductions to both Instructional Insights articles published in this issue.


The objective of this paper is to illustrate how strong coordination leads to the successful combination of the federal and state environmental processes by providing a case study of Doyle Drive – a unique transportation project within a National Park and National Historic Landmark District. This case study recognizes institutional and regulatory constraints and opportunities as well as an understanding of the importance of collaboration and coordination with agencies and the public. Doyle Drive is the southern approach of the Golden Gate Bridge and regional transportation connection between San Francisco and points north. It is located in the Presidio of San Francisco, the oldest continuously operated military post in the nation. The Presidio spans 1,280 acres; boasts spectacular views, a diverse ecosystem, a dynamic shoreline and historic forests; as well as bordering the largest chain of marine sanctuaries in the northern hemisphere. All of these characteristics make environmental stewardship critical to the success of replacing this aging facility. The case study will demonstrate the multiagency, multidisciplined, and multilevel coordination process created to develop broad consensus among three federal land managers and FHWA and over 12 key state and regional agencies throughout the environmental evaluation process – from the project purpose to the development of potential solutions to managing other inevitable challenges such as staff changeover, lack of staff, and differing individual styles within key agencies. It is concluded that the multiagency, multidisciplinary, and multilevel coordination process provided continual interaction among the various agencies and the community – at multiple levels – to identify differing goals, lack of staff continuity in maintaining open communications, and moving the project toward an acceptable conclusion while managing.


Abstract This paper addresses the problem of path-following in two-dimensional space, for underactuated surface autonomous robots, defining a set of guidance laws either at kinematic and dynamic level. The proposed nonlinear Lyapunov- based control law yields convergence of the path following error coordinates to zero. Furthermore, the introduction of a dynamic for the target to be followed on the path, removes singularity behaviors present in other guidance algorithms proposed in the literature. Dynamic of the vehicle is then taken into account, applying the Backstepping technique. Some heuristic approaches are then proposed to face the problem of speed of advance adaptation based on path curvature measure and steering action prediction. Finally a set of experimental results of all the proposed guidance laws are presented.


People who have f e l t uneasy about Ber l in ' s or iginal d i s t inc t ion have often sensed tha t the two notions of l i be r ty were r ea l ly complementary ra ther than contradictory. Being negatively f r e e means having a large number of possible courses of action t o choose between; being posi t ively f r e e means deciding f o r yourself which course t o follow. Without posi t ive freedom, negative l i b e r t y would be poin t less , because i f you are caused t o perform a cer ta in act ion, a l l t ha t matters i s t h a t you a re able t o carry out t h a t action i n pa r t i cu la r , and the value of having a range of actions t o choose between disappears. On the other hand, in the absence of negative l i b e r t y be ing posi t ively free would be merely f rus t r a t ing , because you would be unable t o a c t on many of the choices tha t you might make. l ink between the two concepts i s a value l ink ra ther than a conceptual l ink . k i n d of freedom gives point t o the other. Both appeal t o the underlying image of a choosing subject who i s able t o execute his choices in the external world.


We extend the definition of the conditional min-entropy from bipartite quantum states to bipartite quantum channels. We show that many of the properties of the conditional min-entropy carry over to the extended version, including an operational interpretation as a guessing probability when one of the subsystems is classical. We then show that the extended conditional min-entropy can be used to fully characterize when two bipartite quantum channels are related to each other via a superchannel (also known as supermap or a comb) that is acting on one of the subsystems. This relation is a pre-order that extends the definition of "quantum majorization" from bipartite states to bipartite channels, and can also be characterized with semidefinite programming. As a special case, our characterization provides necessary and sufficient conditions for when a set of quantum channels is related to another set of channels via a single superchannel. We discuss the applications of our results to channel discrimination, and to resource theories of quantum processes. Along the way we study channel divergences, entropy functions of quantum channels, and noise models of superchannels, including random unitary superchannels and doubly-stochastic superchannels. For the latter we give a physical meaning as being completely-uniformity preserving.


Charpy impact testing is a widely used method for the evaluation of the toughness of materials, including 3D-printed plastic parts. This study performed Charpy test on 3D-printed samples made of PLA and ABS. Factors such as layer thickness and infill percentage varied (0.10, 0.15, and 0.20mm layer height and 50, 75, and 100% infill percentage) to investigate how they affect the mechanical properties of 3D printed parts, including their toughness.


To the Editor: With regard to the results of the Centers for Disease Control and Prevention (CDC) Etiology of Pneumonia in the Community (EPIC) study reported by Jain et al. (July 30 issue),1 two related points warrant emphasis. First, although the authors found an increased incidence of pneumonia with increasing age, this study shows that "old" is not so old. The results showed that half of all hospitalizations for communityacquired pneumonia in adults involved patients who were 57 years of age or younger. Second, as noted by the authors, concerted efforts to define a microbial cause did not reveal a pathogen of especially great concern. Responsible microbes were not detected in nearly two thirds of the patients, and no single microbe was associated with more than a small fraction of cases (<9% for every microbe). Thus, pneumonia in adults is less about the microbe and more about the host. The combination of immunemediating antimicrobial activities with homeostatic pathways limiting physiological disruption provides an integrated host defense2 that increases during childhood, in part because of adaptive immunity to respiratory infections,3 but it then becomes compromised by diverse factors during aging, with the result that the risk of pneumonia is increased.4 A person's susceptibility to pneumonia cannot be measured. New tools are needed to diagnose, track, and counter susceptibility to pneumonia, a chronic disease of aging that has not been effectively addressed.


directions. At 2031 h the male oriented its head toward that of the female and rubbed its chin on the female's neck several times before turning to again face in the opposite direction. At 2032 h the male again oriented its head toward that of the female, again rubbing his chin on the female's neck and head; they remained in that position for eight minutes. At 2045 h, both boas had their heads oriented toward the end of the branch


The structure characteristics of fine microstructures are analyzed,the fast tool servo system is designed which can satisfy the machining requirements,the applied formulas of stiffness are presented for different cutter frames which are made of flexible hinges.Furthermore,the sensitive structure parameters are optimized by using the method of orthogonal experiment.The testing experiments show that the stiffness of developed fast tool servo system is 328 N/μm,the natural frequency is more than 3 kHz,the maximal moving displacement is 38.1 μm,and the system can machine fine microstructures efficiently and accurately.


Background: In multiple myeloma (MM), bone-marrow-derived endothelial progenitor cells (EPCs) contribute to tumor neoangiogenesis, and their levels covary with tumor mass and prognosis. Recent X-chromosome inactivation studies showed that EPCs are clonally restricted in MM. In addition, high-resolution array comparative genomic hybridization (aCGH) found that the genomes of EPCs and MM cells display similar chromosomal gains and losses in the same patient. In this study, we performed an integrative analysis of EPCs and tumor cells by genome-wide expression profiling, and applied a bioinformatics approach that leverages gene expression data from cancer datasets to mine MM gene pathways common to multiple tumor tissues and likely involved in MM pathogenesis. Methods: Confluent EPCs (>98% vWF/CD133/KDR+ and CD38−) were outgrown from 22 untreated MM patients' bone marrow aspirates by adherence to laminin. The fractions enriched for tumor cells were >50% CD38+. For gene expression profiling, total RNA from EPCs, MM cells, and control HUVECs were hybridized to cDNA microarrays, and comparisons were made by analysis of variance. Results: Two sets of EPC gene profiles were of particular interest. The first contained genes that differ significantly between EPCs and HUVEC, but not between EPCs and tumor (Profile 1). We hypothesize that this profile is a consequence of the clonal identity previously reported between EPCs and tumor, and that a subset of these genes is largely responsible for MM progression. The second set of important EPC genes are differentially regulated compared both to HUVECs and to tumor cells (Profile 2). These genes may represent the profile of EPCs that are clonally diverse from tumor cells but nevertheless display common gene expression patterns with other cancers. Profile 2 genes may also represent genes that confer a predisposition to clonal transformation of EPCs. When genes in Profile 1 and Profile 2 were overlapped with published lists of cancer biomarkers, significant similarities (P Conclusions: The genomes of EPCs display ranges of overlap with tumor cells in MM, evidenced by gene expression profiles with varying similarity to those found in MM tumor cells. More importantly, MM EPC gene expression profiles, in contrast to normal endothelial cells, contain cancer biomarker genes in tumors not yet associated with MM. Results strongly support the concept that EPCs are an integral part of the neoplastic process in MM.


Innovation is crucial for any modern business, and especially so in a High-Technology environment. For a fastmoving, dynamic and exponentially changing world the demand on high-tech companies to initiate and implement breakthrough innovation for competitive positioning is increasing inexorably. The authors have considerable experience and research background in high-tech engineering companies as consultants, facilitators and academia and have researched the attributes required from different pertinent perspectives to enable breakthrough and sustainable innovation to take place. Innovation in terms of crucial elements for success is considered from the perspectives of Strategy-, System- and Technology Thinking. The Paper represents the results of appropriate research conducted over the last couple of years and suggests a management model to nurture innovation. The research methodology rests on personal research, literature studies and analysis and shows the interaction/influence of various subdimensions related to the three keys, or crucial elements of innovation. Judicious and effective Engineering & Technology Management is a pre-requisite for elevating Innovation practices, specifically the integration of System Thinking in the widest possible sense, Strategic Alignment of all aspects of the business and a sharp focus on the appropriate Technology to be utilized. Considering frequent quantum-jump changes in the global business environment due to (sometimes) revolutionary innovations by competitors create surprises and can lead to low-quality reactive responses. The results of the research lead to the development of an appropriate management methodology to pro-actively lead the way manage and enable effective innovation.


Objective: To analyze the changes of electrocardiogram and thyroid hormone levels before and after 131I treatment of thyrotoxic heart disease. Methods: 160 patients with hyperthyroid heart by 12 lead ECG and serum thyroid hormone levels were tested. Results: The differences on the P wave,T wave,ST,P-R,Q-Tc interval,FT3,FT4 and TSH before and after the treatment had statistical significance( P 0. 05). Conclusion: Electrocardiogram Combining with thyroid hormone level is an important method to guide the radionuclide therapy on hyperthyroid heart disease.


A task-based assessment of image quality1 for digital breast tomosynthesis (DBT) can be done in either the projected or reconstructed data space. As the choice of observer models and feature selection methods can vary depending on the type of task and data statistics, we previously investigated the performance of two channelized- Hotelling observer models in conjunction with 2D Laguerre-Gauss (LG) and two implementations of partial least squares (PLS) channels along with that of the Hotelling observer in binary detection tasks involving DBT projections.2, 3 The difference in these observers lies in how the spatial correlation in DBT angular projections is incorporated in the observer's strategy to perform the given task. In the current work, we extend our method to the reconstructed data space of DBT. We investigate how various model observers including the aforementioned compare for performing the binary detection of a spherical signal embedded in structured breast phantoms with the use of DBT slices reconstructed via filtered back projection. We explore how well the model observers incorporate the spatial correlation between different numbers of reconstructed DBT slices while varying the number of projections. For this, relatively small and large scan angles (24° and 96°) are used for comparison. Our results indicate that 1) given a particular scan angle, the number of projections needed to achieve the best performance for each observer is similar across all observer/channel combinations, i.e., Np = 25 for scan angle 96° and Np = 13 for scan angle 24°, and 2) given these sufficient numbers of projections, the number of slices for each observer to achieve the best performance differs depending on the channel/observer types, which is more pronounced in the narrow scan angle case.


Aspirin, one of the most widely applied medicines, not only possesses the effects on reducing fever, anti-vascular hyperplasia, and anti-inflammation, but also has the capacity of preventing platelet aggregation. So far, it is acceptable to adopt aspirin, especially low-dose aspirin (LDA), to prevent pregnancy-related complications, such as pregnancy complicated by antiphospholipid syndrome, systemic lupus erythematosus, or preeclampsia; unexplained recurrent spontaneous abortion; fetal growth restriction; and preterm birth. In this article, we reviewed the possible mechanism of action and applications of aspirin in these pregnancy-related complications.


The COVID-19 pandemic has disproportionately affected underserved and minority populations in the United States. This is partially attributable to limited access to diagnostic testing from deeply rooted structural inequities precipitating higher infection and mortality rates. We describe the process of establishing a drive-through collection site by leveraging an academic-community partnership between a medical institution and a federally qualified health center in Minnesota. Over 10 weeks, 2006 COVID-19 tests were provided to a socioeconomically disadvantaged population of racial/ethnic minorities and low-income essential workers. (Am J Public Health. Published online ahead of print February 18, 2021: e1-e5. https://doi.org/10.2105/AJPH.2020.306097).


Several novel relative-humidity sensors based on fiber Bragg grating and various pore-foaming agent doped polyimide coating are proposed and demonstrated. Sensing characteristics of lithium chloride, acetone and methyl alcohol doped polyimide coated sensors were investigated, and all sensors show good stability and linear response during the experiment. The corresponding sensitivities are 1.71, 0.53, and 0.63 pm/%RH, respectively. Compared with the polyimide coated sensor (0.62 pm/%RH), the humidity sensor based on additive of lithium chloride can significantly enhance the sensitivity (2.76 times). Moreover, the proposed humidity sensors display linear response under different temperatures, which make it easier for the temperature compensation. Therefore, humidity sensor based on lithium chloride doped polymer sensor is promising to detect humidity fluctuation in some special facilities.


While cultural reductionists and right-wing populist politicians point to the incompatibility of Western and Arab identity or cultural values, we speak to young Arabs living in Canada to understand how they eschew such discursive narratives by nurturing self-knowledge through hybridity. This nurturance allows for transcultural identity formation. It is made possible when youth embrace their multiple cultures, identities, and senses of belonging through open-minded exploration. In this chapter, we investigate the transcultural identity formation of Arab youth through an epistemology of metissage that challenges the idea that Canadianness is an alterity to them. We draw upon survey results from over 860 Canadian-Arab youth and structured focus groups with two hundred youth. We ask them how art, music, culture, and social media shape their conceptions of the world, and explore how Arab youth in Canada navigate their identities and stay translocally and transnationally connected to the people, spaces, and objects associated with their home country cultures. We find that Arab youth hybridize their lives by balancing attachment and longing, living in Arabic culture, demarcating the inside and outside of cultural boundaries and choosing positions on an issue-by-issue basis, and pursuing Arab-Western metissage as an identity.


research would meet the ethical standards of research involving human participants, and would promote the safety and well-being of the seller; this clause helps to ensure that the sellers will receive adequate postnephrectomy surveillance and follow-up care, which would work to mitigate postsale backfire. Importantly, this prototype kidney market would make it mandatory for all participants to read and demonstrate understanding of relevant empirical findings (such as those of Koplin and those he cites), prior to their participation therein—something that is altogether absent in current black markets, and (presumably) the Iranian market as well. ("Many people who have sold one of their kidneys come to view their bodies as damaged or disordered, and routinely fear their imminent demise," "There is a statistically significant number of those that sell their kidney who come to regret their decision to do so, and reversing the nephrectomy is likely practically impossible," "If your current or foreseeable primary mode of employment depends on physical labor, then your risk of long-term postsale backfire increases significantly," "If you do not have adequate health care coverage, and/or have reservations about seeking postsale medical care, then your risk of long-term postsale backfire increases significantly," "For many people, the economic benefits of selling their kidney are temporary, and for others they are nonexistent," etc.) This clause would serve to increase participant protection and awareness, enabling them to realistically weigh the prospect of postsale backfire with the alternative of leaving things as they are, for them. Ultimately, however, it would be up to them to decide whether to sell their kidney, in an attempt to improve their plight, with the knowledge that there is a fairly high probability that their doing so will turn out to be a mistake (for them to make). &


We report results of safety climate questions from health care professionals involved in the "Systems Engineering Intervention in Outpatient Surgery - a Collaborative Community Perspective" study undertaken at the University of Wisconsin-Madison. Surveys were conducted in five outpatient surgery centers pre- and post-intervention. The objectives of this study were to examine patient safety climate across various outpatient surgery centers pre- and post-specific patient safety interventions and to examine the relationship between patient safety climate and job categories, individual outpatient centers and the respondents' Quality of Working Life (QWL). Our results indicate that four patient safety climate scales can be created from the pre- and post-intervention 12-item questionnaire: (1) Top management commitment to patient safety, (2) General patent safety climate, (3) Employee commitment to patient safety and (4) Patient safety change. In one of the survey centers, patient safety climate became more negative over time.


The article analyzes the correlation between the theory and history of psychology on the basis of a concept, which is formed in the process of researching the work of the outstanding Ukrainian scientist V. A Romenets. According to the concept, psychological cognition is a historical-logical-psychological process that is carried out on an epistemological basis and runs from dualism to monism; stages of the process are ways to solve the main problem of psychology, which fixes the need to characterize the mental as subjective in view of the objective; patterns of the process illuminates the thinking of the author of the theory of mind in solving this problem. The state of theoretical psychology is critically assessed, the latter is understood as marked by the theory of mind progress of psychological cognition. The example of V. A. Romenets' creative dialogue with his predecessors shows that the theory is evidence of the author's extraordinary place in this process. The search for the place of man in cognition ends with the proclamation of man as a subject of cognition, a body of self-knowledge of the world, capable of comprehending an object within the limits of its thinking. In epistemology, it is substantialism, proceduralism; the principle of observation is opposed by the principle of involvement; man's place in cognition is characterized either dualistically or monistically. The idea of the identity of thought and being means that the condition of cognition is the coincidence of the way of understanding an object with the way of its existence. The philosophy of science either denies or affirms the principle of involvement, the same thing happens in the psychology of science. Subjectocentrism in epistemology is echoed in psychology by the opposition of the subjective to the objective, overcoming this opposition generates monistic theories in both epistemology and psychology. In psychology, this is the main problem; it is accentuated by the circle of cognition that the psychologist enters into when, using his own psychic, he explores the nature of the psychic. The problem – a source of psychological knowledge, the circle – evidence of the direct presence of a psychologist in this process. Marxist psychologists solve the problem monistically, in terms of the category of practice. Solutions encounter difficulties, ideas deepen the content of the category of practice and open the possibility of new solutions to this problem. Psychologists of the post-Soviet era do not think as a category of practice and, in contrast to the activity-based, assert the subjective approach. From an epistemological point of view, this is subject-centrism, and from a historical and psychological point of view, it is a step in the opposite direction. According to V. A. Roments, the main way of practice is the act as a contradictory interaction of subjective and objective, which is engraved in the history of human self-knowledge. The dynamics of the components of the act highlights the historical and ontogenetic path of man, the essence and purpose of mental, historical levels of psychological knowledge. In the work of the scientist, psychology reaches a post-classical level of development. For classical psychology, the subjective and the objective are disproportionate entities, for non-classical – the sides of reality, for post-non-classical - the side of the human way of life. The main problem of psychology is solved in fundamentally different ways; the solutions illuminate the path of psychology from dualism to increasingly meaningful monism. Analysis of the work of V. A. Romenets shows that the progress of thinking of the psychologist expresses the historical progress of psychology, which occurs when the way of thinking coincides with the way of being mental. The idea of the identity of thinking and being is illustrated, which logically completes the search for the place of man in cognition in epistemology. The inherent explanation of the nature of the mental circle of cognition expands to the limits of the existence of the mental, and the monistic solution to the basic problem of psychology no longer stands in the way. V. A. Romenets creates a theory of the way of human existence at the historical and ontogenetic level, it is actual to characterize the way of human existence at the individual level on the basis of category of being in the subject-practical content, to implement the anthropological approach in psychology and overcome the gap between theoretical and practical branches of this science.


The article is devoted to one of the current issues related to the concepts of "personality" and "linguistic personality" – a reflection of the personality development process through the language. The most frequently used lexical means, which can show the dynamics of personality development have been singled out in the English texts and Russian translations. The activity degree of selected linguistic units in the original texts and the degree of their equivalence and activity in the translation are defined.


Massive unprecedented changes, that best describe this era, are affecting the accountant and auditor profession, as well as the global business environment. The traditional role of the financial auditor will change, but if it will adapt and provide new services, may become a trusted councillor for its clients. The way financial auditors approach future tendencies will shape the destiny of the accountant and auditor profession. Financial auditors must understand innovation, to be open towards globalization, to be prepared as human resources that are competing not only nationally but also globally.


Law of Promoting Civilian-run Educations a fairly good politic law that can be really carried out at present; but there are quite a lot of places there that remain to be perfected. Such insufficiencies can be remedied by making implementing regulations.


While the unidentified poet of the Old Saxon Gospel harmony the Heliand uses Tatian's Diatessaron as the primary source for his work, scholarship has long noted that the author makes changes to the content, imagery, and lexicon of his source in order to acclimate his Saxon audience to the Christian Gospel. One notable redaction is that, despite being an adaptation of the life of Jesus, the name Jesus appears only five times over the course of the poem's six thousand lines. The first of these uses, found during an angel's visit to Joseph before the birth story, is particularly notable because the angel seems to contradict an earlier directive; during his visit to Mary, Gabriel instructs the Virgin to name her child Heliand, while the angelic messenger who speaks to Joseph during his dream gives the child the name Iesu. Though seemingly a contradiction, the angel's instruction to Joseph regarding the Christ Child's name reflects the Saxons' pre-Christian child-naming rituals, thereby helping to situate the unfamiliar narrative within recognizable cultural imagery.


Modeling of gas/liquid mass transport requires knowledge concerning the behavior of near-surface concentration fluctuations at clean and film-covered gas/liquid interfaces. Previous measurements of concentration fluctuations were performed with invasive sampling techniques or for water surfaces of unknown cleanliness. Here, concentration fluctuation depths were calculated from noninvasive laser-induced fluorescence measurements of surface fluorescence fluctuations for carefully cleaned and film-covered water surfaces for a range of turbulence intensities. Comparison of the film-covered water surface concentration fluctuation depths to previous measurements of concentration fluctuations shows that the calculational procedure provides accurate estimates of fluctuation depths.


Vladivostok is notable with significant limitations in arranging pedestrian spaces in the traditional way, namely along highways. Therefore, the most essential task is to develop those pedestrian spaces that connect areas separated by a significant difference in terrain, highways, and railways along the shortest distance. The article discusses the experience of national and foreign design of pedestrian spaces formed independently of city highways and assuring a comfortable traveling for pedestrians under any weather conditions. Studying the experience of using technical means and mechanisms will allow outlining the main ways of the architectural and spatial arrangement of year-round urban pedestrian spaces in the conditions of hostile terrain and monsoon climate.


First results of geologic architecture of Verkhnechon field (Siberian Platform) by modern 3D seismic data are presented. It is established that narrow grabens, crosscutting sediments, regional and local components changing Vendian terrigenous complex thickness are reliably mapped by seismic. The results of Vendian terrigenous complex facies analysis are examined. Correlations between seismic attributes, impedance and linear content of VC1 are scrutinized. Scheme of VC1 reservoir linear capacity enabling the recognition of risk zones for locating development wells is provided.


Mode selection of a moderate power gyrotron operating at the ISM frequency and the second harmonic is discussed in detail. By analysis and calculation for electron beam wave coupling, mode competition, voltage depression and limiting current, and ohmic losses, considering the compactness of the configuration, the result obtained is that TE 31 mode is probably a best choice for the technology gyrotron operating at the ISM frequency.


With the exception of fiber exhaust situations, many carriers have been slow to adopt DWDM in metro networks due the cost and complexity of dealing with this technology. Instead carriers continue to deploy non-WDM point- to-point, stacked SONET rings. While easy to deploy and manage, stacked SONET ADM rings are inherently inefficient. Pass through traffic must be needlessly regenerated multiple times. Stacking boxes in the central office can use up precious space and power. Utilizing and managing multiple physical rings is cumbersome at best. In addition, an ADM ring is a shared resource. While a 2.5G or 10G ADM ring sounds like high capacity, actual protected bandwidth per node is only 1/N on average - where N is the number of nodes in the ring. For a 16 node, OC-48 UPSR ADM ring, the usable per node bandwidth is only 155MB/s (a single OC-3). For high capacity routes, multiple rings must be overlaid. Thus, fiber pairs, once thought to be an infinite resource, are quickly being used up.


This research offers as its main contribution a complete treatment of equation solving within process algebra for equation systems of the following form: C/sub 1/(X) approximately P/sub 1/, . . ., C/sub n(X)/ approximately P/sub n/ where C/sub i/ are arbitrary contexts (i.e. derived operators) of some process algebra, P/sub i/ are arbitrary process (i.e. terms of the process algebra), approximately is the bisimulation equivalence, and X is the unknown process to be found (if possible). It is shown that the solution set to this equation may be characterized in terms of a distinctive modal transition system, and that a solution to the above equation systems may be readily extracted (when solutions exist) on this basis. In fact, the results have led to an implementation (in Prolog) of an automatic tool for solving equations in the finite-state case.<<ETX>>


ABSTRACT Researchers have found that when young people participate in discussions of controversial political issues, they often become more politically engaged and informed (Hess, 2009). Nonetheless, some educators avoid fostering such discussions because they can become heated and distract from academic learning (Hess, 2002). Presidential elections, including the highly publicized debates, provide substantial material for discussions of major national and international issues, but no published research has examined how educators can leverage these events to generate productive civic learning experiences. In this article, we analyze data collected in seven high school classrooms during the 2012 presidential election to examine the challenges and opportunities associated with generating substantive, dynamic discussions of presidential debates. Our findings indicate that students enjoyed learning about candidates' different perspectives and that certain strategies were especially helpful for fostering substantive discussions: (a) scaffolding students' preparation for discussion; (b) providing opportunities for students to address open-ended questions; (c) redirecting students' engagement in competitive, interpersonal dynamics to learning about public issues; and (d) countering students' partisan tendencies. We discuss implications for practice and research and present a conceptual framework for generating dynamic, substantive democratic discussions.


A 645-kDa proteasome was purified from Methanosarcina thermophila which had chymotrypsin-like and peptidylglutamyl-peptide hydrolase activities and contained α (24-kDa) and β (22-kDa) subunits. Processing of both subunits was suggested by comparison of N-terminal sequences with the sequences deduced from the α- and β-encoding genes (psmA and psmB). Alignment of deduced sequences for the α and β subunits revealed high similarity; however, the N-terminal sequence of the α subunit contained an additional 24 amino acids that were not present in the β subunit. The α and β subunits had high sequence identity with α- and β-type subunits of proteasomes from eucaryotic organisms and the distantly related archaeon Thermoplasma acidophilum. The psmB gene was transcribed in vivo as a monocistronic message from a consensus archaeal promoter. The results suggest that proteasomes are more widespread in the Archaea than previously proposed. Southern blotting experiments suggested the presence of ubiquitin-like sequences in M. thermophila.


Chlorpyrifos pesticide containing insulation materials release, slow-release pesticide technical field belonging to the insulation material. The percentage by weight of the components of the following composition: 1 to 10% chlorpyrifos, additives 0.1 to 25%, 50 to 90% of carrier, from 0.1 to 25% modifier. Chlorpyrifos-containing sustained release of the insulating material of the present invention, operations for covering shoots, shoots both prevention of soil pests, effective prevention and control, long persistence in the soil but not cause residual pesticide affect shoots food security; and holding moisture can play a regulatory role for bamboo shoots, the shoots to promote growth, accelerate the speed of bamboo shoots to produce better economic results.


Monometallic catalysts based on copper phyllosilicates were actively studied in the 2000s as an alternative to the copper-chromium Adkins catalyst due to their non-toxic properties and high activity in the...


The report shows the size and evolution of the scientific production of the National University of La Plata (UNLP) published during 2006- 2010 in journals indexed in international databases like WoS, Scopus, COMPENDEX, EBSCO, ProQuest, KW-OVID, PubMed, LILACS, and others.


It is important to elucidate the effects of heparin on the α2-antithrombin (ATIII) inactivation of serine proteases in order to understand the pharmacological activity of heparin. We have studied the enzyme kinetics of the ATIII inactivation of these proteases, and the effects of heparin on these interactions, using a common amide peptide substrate and protein substrates. We also studied the interactions of heparin with the three proteases. We conclude that the mechanism of the catalytic effect of heparin (observed at 0. 005 unit/ml) toward the thrombin- ATIII reaction is different from the mechanism whereby heparin (only at very high concentration, e.g., 10 unit/ml) can induce an enhanced rate in the plasmin-ATIII reaction. We conclude that the first mechanism involves a heparinthrombin complex, while the mechanism with plasmin involves a heparin-ATIII complex which forms only at high heparin concentrations. This is consistent with known appropriate binding constants. We found that heparin has no effect on the very rapid inactivation of trypsin by ATIII. We further conclude that there is no common mechanism whereby clinically relevant levels of heparin cause general enhanced ATIII-protease reaction rates. We suggest ATIII depletion during heparin therapy might be avoided by using low heparin levels, which would not allow heparin-ATIII complexes to form, yet which would catalyze the thrombin-ATIII reaction. Our finding that ATIII inactivates trypsin at a rate similar to the heparin-catalyzed thrombin-ATIII reaction suggests a physiological role for ATIII in the control of trypsin-like enzymes.


Due to their internal complexity, English conditionals represent a challenge for L2 learners; furthermore, most ESL grammar books lack precise explanations of conditional meanings and usage contexts. As a solution, cognitive linguistic research on conditionals (Dancygier and Sweetser 2005), based on theory of conceptual blending and mirroring human cognition processes, could be very beneficial for L2 learners. In this study, elements of cognitive linguistic analysis of English hypothetical conditionals were incorporated into L2 learning materials. The design of the study was quasi-experimental, with three groups (N = 57) participating: cognitive, task-supported, and control. Pedagogic consciousness-raising tasks were used to provide a context for meaningful practice for cognitive and task-supported groups. The research questions explored the efficacy of different types of instruction for L2 development of English conditional phrases, as measured by a post-test and a delayed post-test. The findings of t-test and analysis of variance procedures (p = .001) indicate that participants from the cognitive group outperformed the participants from the task-supported and control groups and demonstrated a higher degree of understanding of conditional usage contexts.


Budesonide, a glucocorticosteroid is generally used to treat chronic inflammation and asthma. Hepatic first-pass metabolism and poor solubility are the major causes of its limited oral bioavailability. Present work was undertaken for the preparation of hydrogel film formulation with cyclodextrin complexation of budesonide containing quaternary surfactant for possible enhancement of mucosal permeation. FTIR study confirmed drug-polymer hydrogen bonding. Almost complete amorphization of the drug was pronounced by SEM, DSC and XRD studies. The film containing benzalkonium and hydroxypropyl beta-cyclodextrin exhibited in vitro dissolution and mucosal permeation to the highest extent of 87.2 and 95.8 % respectively in contrast to the others. Film formed hydrogel in aqueous mucin and enhanced the mucosal tissue residence time due to the mucoadhesive nature of the polymer. Acute inflammation in the rabbit eye was controlled within 3 h by applying the film in the cul-de-sac. The presence of cyclodextrin and quaternary surfactant brought about significantly improved drug release and mucosal permeation compared to their absence in the HPMC film. Hydrogel formed in aqueous mucin enhanced the mucosal residence time and controlled acute inflammation in the rabbit eye within 3 h after topical application.


This work concentrates on vision processing for ADAS and intelligent vehicle applications. We propose a color extension to the disparity-based Stixel World method, so that the road can be robustly distinguished from obstacles with respect to erroneous disparity measurements. Our extension learns color appearance models for road and obstacle classes in an online and self-supervised fashion. The algorithm is tightly integrated within the core of the optimization process of the original Stixel World, allowing for strong fusion of the disparity and color signals. We perform an extensive evaluation, including different self-supervised learning strategies and different color models. Our newly recorded, publicly available data set is intentionally focused on challenging traffic scenes with many low-texture regions, causing numerous disparity artifacts. In this evaluation, we increase the F-score of the drivable distance from 0.86 to 0.97, compared to a tuned version of the state-of-the-art baseline method. This clearly shows that our color extension increases the robustness of the Stixel World, by reducing the number of falsely detected obstacles while not deteriorating the detection of true obstacles.


Summary. Clinicians and researchers have considered occlusion as one of the main direct and/or indirect etiological factor that cause temporomandibular disorders (TMD) for many years. The relationship between occlusion and TMD (temporomandibular disorders) has been based on the observation of an anatomical relationship between tooth position and jaw function for a long time, as well as on the higher prevalence of TMD in people with malocclusion compared to the general population. A significant number of studies have examined factors associated with occlusion and malocclusion as a potential mechanism for the development of signs or symptoms of TMD. At the same time, there are other concepts for the development of TMJ pathology. Aim of the research: to analyze modern views on the etiological factors of temporomandibular disorders according to the latest sources of scientific and medical information. Recent scientific trends have shifted the focus of TMD etiology from biomedical to a more complex multi-factor biopsychosocial model that includes biological, psychological, and social factors. Therefore, a proper understanding of the relationship between «occlusion» and SNA seems extremely important, since a paradigm shift requires a more comprehensive interpretation of the concepts of occlusion and maxillary relationships. The role of malocclusion in the etiology of temporomandibular disorders should be considered limited, unless a causal relationship is proven. Instead, clinicians should pay serious attention to patients «occlusal awareness» and concerns during general and dental consultations, as some patient groups may develop iatrogenic maladaptive behavior. Key words: temporomandibular joint, temporomandibular disorders, occlusion, malocclusion, splint therapy, prosthetic and orthodontic treatment.


Image segmentation is an important and challenging problem in image analysis. Segmentation of moving objects in image sequences is even more difficult and computationally expensive. In this work we propose a technique for spatio- temporal segmentation of medical sequences based on K-mean clustering in the feature vector space. The motivation for spatio-temporalsegmentation approach comes from the fact that motion is a useful clue for object segmentation. Two- dimensional feature vector has been used for clustering in the feature space. In this paper we apply the proposed technique to segmentation of cardiac images. The first feature used in this particular application is image brightness, which reveals the structure of interest in the image. The second feature is the Euclidean norm of the optical flow vector. The third feature is the three- dimensional optical flow vector, which consists of computed motion in all three dimensions. The optical flow itself is computed using Horn-Schunck algorithm. The fourth feature is the mean brightness of the input image in a local neighborhood. By applying the clustering algorithm it is possible to detect moving object in the image sequence. The experiment has been conducted using a sequence of ECG-gated magnetic resonance (MR) images of a beating heart taken as in time so in the space.


This paper introduced the basic characteristic of Riter Confor\|Spin system and Suessen Eliter\|spin system,according to the review of new type spinning frame on international textile machinery fair,and the analyses of performance and structural characteristic on compact yarn,the conclusion was drawn as follows,the method with compact spinning is beneficial to some fields,such as the continuousize,raising the product quality and the labor productisity,the technique key on improving the technical level of domestic ring spinning frame is to study compact spinning new technique.


The starting point of establishing rules and forms of Chinese classical poetry includes the exploration of rhythm and the use of level and oblique tones.The earliest exploration of Chinese rhythm concerned the introduction of Buddhism in the Han Dynasty.When poets in the Han Dynasty wrote Five Characters Poetry,some of them used the research results about Chinese rhythm.The study of Chinese rhythm was progressed increasingly in the Wei and Jin Dynasties.At the same time sentences and couplets of Five Characters Poetry accordding to the rules and forms of Chinese classical poetry appeared in abundance.It shows that poets in the Wei and Jin Dynasties paid close attention to rhyme rules.


Expert brain tumor identification on multi-modal Magnetic Resonance (MR) images is a very time-consuming process for medical experts. Therefore, throughout the last decade, significant effort has been invested in the development of novel approaches applying computer-aided techniques for brain tumor segmentation. Automated brain tumor segmentation aims to separate and label different tumor tissues, including: (1) active tumor cells, (2) necrotic core, and (3) edema from normal brain tissues of Gray Matter (GM), White Matter (WM), and Cerebrospinal fluid (CSF). Even though experts from the brain tumor research area can accurately characterize and identify brain tissue abnormalities, the automated process of tumor segmentation is not straightforward. Many accurate approaches are only evaluated on a single data type coming from a particular brain tumor type, and thus, being far away from a practical clinical application [1].

The aim of this work is to implement a software framework to apply and evaluate a recent technique of automated brain tumor segmentation in realistic clinical settings. We will use the algorithms on a coherent study data set and evaluate how they perform based on a small annotated data set.

The algorithm choice will be based on quantitative evaluations from [2], [3]. Additionally, internal requirements for the selection will be defined (i.e. degree of user supervision, robustness on the various data, etc.). The dataset consists of multi-contrast MR clinical images from [2], [3], as well as, images from the repository of Medical University of Vienna. The robustness of the selected approach will be evaluated using test data from [2], [3]. The performance measure includes segmentation accuracy of each tumor sub-region defined in 1-3, brain tumor type and the severity of the pathological case.

The expected outcome of this project is a toolbox for brain tumor segmentation using existing algorithms. The robustness of the state-of-the-art approaches will be evaluated providing a rough estimation of how far selected techniques are from a practical usage in clinical practice.

!!Acknowledgements
Special thanks to Prof. Dr. Georg Langs form Computational Imaging Research Lab for opportunity to work on this project.

!!References
[1] T. Haeck, F. Maes, and P. Suetens, "An untrained and unsupervised method for MRI brain tumor segmentation," in Proceedings ISBI 2016, 2016, pp. 265–268.
[2] B. Menze, A. Jakab, and S. Bauer, "The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS)," IEEE Trans. Med. Imaging, pp. 1–32, 2014.
[3] "Multimodal Brain Tumor Segmentation Challenge (BRATS)," 2015. [Online]. Available: http://braintumorsegmentation.org/. [Accessed: 15-May-2016].


ABSTRACT Inhibitory Effect of Polygonum Multiflorum on Melanin Synthesis and Its Action Mechanism in B16F10Jong-Sek Song, Dong-Youl YooDept. of Oriental Medicine Graduate School, Daejeon UniversityPurpose: This study was performed to determine the inhibitory effect of Polygonum multiflorum(PM) on melanin synthesis in B16F10.Methods: The Inhibitory effects of Polygonum multiflorum(PM) on melanin synthesis were determined by in-vitro assay. To elucidate inhibitory effects of Polygonum multiflorum on melanin synthesis, we determined the melanin release and melanin production in B16F10. And to investigate the action mechanism, we assessed the gene expression of tyrosinase, TRP-1, TRP-2, MMP-2, PKA, PKC, ERK-1 ERK-2, AKT-1, MITF in B16F10.Results: 1. PM inhibited melanin-release, melanin production in B16F10.2. PM inhibited tyrosinase activity in vitro and in B16F10.3. PM suppressed the expression of tyrosinase, TRP-1 in B16F10.4. PM suppressed the expression of PKA in B16F10.5. PM suppressed the expression of ERK-1, ERK-2, AKT-1 in B16F10.6. PM suppressed the expression of MITF in B16F10.Conclusion: From these results, it may be concluded that PM possesses the antimelanogenetic effects.Key Words: Polygonum multiflorum(PM), whitening, melanogenesis, Tyrosinase.


The initiation of many physiologically important biochemical reactions is dependent on the binding of a molecule or molecules from solution to an appropriate solid surface such as a cell membrane. The quantitative study of dynamic interactions of molecules in solution with immobilized surfaces under physiologically relevant conditions presents a significant physical problem. Traditionally these measurements have been performed by discontinuous, nonequilibrium assays that cannot accurately model in vivo reaction mechanisms. Total internal reflection fluorescence spectroscopy (TIRFS) is an analytical technique that is based on the excitation of fluorescence by means of an exponentially decaying surface energy wave called the evanescent wave. The limited ''penetration depth'' of the evanescent wave leads to excitation of fluorescent molecules at or near the surface. This phenomena makes TIRFS uniquely qualified for the dynamic fluorescence study of liquid‐solid interface binding reactions. The instrument des...


This article introduce the producing process of permanent antimycotic and antiseptic top.The top is made after solidifying the antimycotic detergent on the fibre though the special technique.The acrylic top and its post manufactured products have the permanent function of resisting and killing the bacteria as well as preventing the septic smell of the microbe.This kind of new product can guide the enterprises to develop the functional health protecting products,enlarge the usage of the special textile materials,satisfy the requirement of the consumers to the heath keeping textile products.


Unless treated with high doses of oral calcium or vitamin D metabolites, the patient with end-stage renal disease (ESRD) undergoing dialysis is usually in a state of negative net calcium balance at the level of the intestine and has negligible urinary calcium losses. The negative net calcium flux across the intestine can be reduced or even made positive by the administration of large doses of calcium supplements (as used in calcium-based phosphate binders), or of 1α-hydroxylated metabolites of vitamin D, or both. At the level of the peritoneum, calcium mass transfer can also be rendered positive or negative, in this case, by adjustments to the calcium concentration of the peritoneal dialysate. Historically, it was usual to set dialysate calcium concentration at 1.75 mmol/L, this concentration being substantially above the concentration of diffusible calcium in plasma and extracellular fluid. As a result, the dialytic process was


Gender differences in mathematics learning continue to attract much research attention. Single-sex settings as the preferred option for improving schooling for girls have evoked fierce advocates as well as critics. This case study, undertaken in response to a specific request from a co-educational state school in the outer area of Melbourne, Australia, and with its maximum cooperation, examined both the shorter and longer term effects on students' attitudes and performance in mathematics of the introduction of single-sex mathematics classes at the grade 10 level. Important dimensions of the study included surveying students in as well as out of the program, seeking the reactions of parents to this initiative, and the opportunity to assess the effect of the introduction of such classes at grado 10 instead of at lower grades (7 and 8), where such interventions have more typically been tried. Results include: (1) Both female students and mothers were more favorably inclined towards the single-sex mathematics program than were their male counterparts; (2) Performance levels for males and females were not significantly different throughout the project year; and (3) Anticipated and actual subject choices for grade 11 were no different for males and females; however, .anticipated subject choices for grade 12 showed more differences between males and females than past state average statistics. Contains 10 references. (Author/MKR) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. SINGLE-SEX MATHEMATICS CLASSES IN A CO-EDUCATIONAL SETTING: Gilah C. Leder Graduate School of Education La Trobe University Bundoora, Victoria Australia 3083 -PERMISSION TO REPRODUCE THIS MATERIAL HAS BEEN GRANTED BY


The purpose of this study was to identify intrapsychic processes of self socialization in sex role development during late childhood and adolescence. For this purpose I investigated the sex-role stereotypes, sex-role ideology, sex-role identity, and self- esteem of 6th, 8th, and 10th graders and examined the causal relationships among these sex-role variables. Data were gathered through questionnaires administered twice with an interval of three months. The methods of analysis were one-way ANOVA, χ², and multiple regression. The results showed, (1) Adolescents` sex-role stereotypes had significant relationships with sex typing. Subjects with low scores on sex-role stereotypes were more likely to show opposite sex typing. (2) Sex-role ideologies had significant relationships with sex typing. As Subjects agreed more with egalitarianism, they were more likely to exhibit opposite sex typing. (3) Adolescents` sex typing had significant relationships with their self-esteem. The androgynous group exhibited the highest scores on self-esteem. (4) Path analysis from the multiple regression analysis indicated different processes between sexes in sex-role development. In the boys` sex-role development, it was found that only masculinity contributed to self-esteem. Girls` masculinity also contributed most to self-esteem, but other sex-role variables such as femininity and sex-role stereotypes made some contributions to girls` self-esteem.


In chapter eight of his recent books Perception, Sensation and Verification (Clarendon Press, 1972) Mr. Bede Rundle asserts that light, not colour, is the proper object of vision. The light that he has in mind is that which is the object rather than the stimulus of sight. A good example would be the beam of a torch. Our seeing such a beam, he recognises, may be shown to be dependent on the illumination of dust-particles by the other sort of light, but he suggests that it is quite possible that such light should have no material basis. Mr. Rundle proposes two criteria for something's being the proper object of a sense (op. cit. pp. I62-I63). The first (CR i) is that it can be perceived only by that sense. The second (CR 2) is that it is perceived by that sense whenever anything is so perceived. He then suggests that in respect of vision light fulfils both these criteria. Now light does seem to satisfy CR i. How, for instance, could one perceive a torch-beam if not by sight? Mr. Rundle's problem is to convince us that light fulfils CR 2. To do this he has recourse to an argument, which I shall now summarize.


GridStat is a QoS-managed middleware framework designed to replace the power grid's aging, inflexible, and slow data communications system. GridStat is a specialization of the publish-subscribe paradigm that takes advantage of the semantics of periodic updates of cached sensor data to provide data delivery with a per-subscriber rate, latency, and redundant paths. While GridStat is well-suited for delivery of sensor data over a wide-area network, its baseline one-way mechanisms are not suitable for round-trip invocations such as setting an actuator or calling between control centers. In this paper we present the design, implementation and experimental evaluation of Ratatoskr, a tunable remote procedure call mechanism that builds on the QoS semantics of GridStat and supports three kinds of redundancy. Additionally, user-defined pre- and post-condition predicates over GridStat status variables are built into the call semantics.


Investigation of two redox oxidation systems : ethane oxidation on vanadium oxide and propylene oxidation on molybdenum oxide. Kinetic and spectroscopic evidence indicates that different intermediates are involved in the reaction pathways that lead to selective and unselective oxidation


Programming teaching is currently included in a wide range of academic and technical courses mostly due to technological advances. Despite the fact that this approach is reaching more and more students, the literature has described a set of limitations in the acquisition of this complex learning and presented microworlds as a possible solution. Although they have been closely associated with constructivist models combined with the 4C/ID model, they have shown promising results in recent studies. This chapter explores the use of microworlds associated with the 4C/ID model to facing the learning difficulties on programming in technical courses. It also presents a set of practical examples that the reader could put into practice.


The study seeks to determine how much environmentally conscious behaviors vary depending on the nationality, gender and age. For its purpose, this study suggests hypotheses that Korean and American consumers, who are culturally different from each other, show differences from each other in environmentally conscious behaviors. An interaction effect is also expected between gender and age. With regard to environmentally conscious behavior. Meanwhile, the study tried to examine whether personal values have any mediating effect on the behaviors. The findings of this study can be summarized as follows. Environmentally conscious behaviors by American consumers were more significant than those by Korean consumers. And men were more positive in making environmentally conscious behaviors than women were. In addition, there were interaction effects between nationality and gender, and nationality and age. Furthermore, personal values, depending on age, were found to have moderating effects on environmentally conscious behaviors.


Antimonide laser has a very promising application prospect in the 2~5μm wavelength region.The paper summarizes the development of antimonide laser and elaborates the material growth,structure design,device pro- cessing,packaging technology and new laser structure.It also discusses the principal technical issues in the research and points out the trends of extending continuously to long wavelength for antimonide lasers.


This research was the purpose to identify the conditions in which a group of teachers develop their teaching practice in urban, rural and marginalized commun...


In this study, "Influence of textileria in economic development district Huamachuco, Sanchez Carrion Province," the report begins with a specific analysis of the textiles and as has been developed.
In order to determine how it influences the economic development textileria Huamachuco, was reached to raise the following problem: how to influence its economic development textileria District Huamachuco, Sanchez Carrion Province? Allowing us to determine that the high degree textileria influences on economic development in the district.
Data processing was used correlational descriptive statistics, which results in the analysis and interpretation of statistical tables for the variables under study.
After analyzing the results we conclude that the totality of the members of the association believe that the textileria plays an important role to make the city of Huamachuco to develop economically and thus help improve education, health and other indicators.
The recommendation we can make known is that it is necessary to train the artisans on new techniques of mass production, likewise participate in national and international fairs to promote their products


The rapid shift from traditional face-to-face instruction to virtual platforms has fundamentally reshaped higher education, including English courses. Post-Covid-19, online learning has proven to be a sustainable, long-term option. This study examines the perspectives of 46 Malaysian higher-education instructors delivering online English courses. The study has three objectives: identifying challenges in online teaching, exploring instructors' perceptions of digital tools and resources, and investigating views on transitioning to a fully-fledged Open and Distance Learning (ODL) mode. Findings highlight technical issues as the primary concern accompanied by varied perspectives. Addressing these challenges and optimizing digital tools and resources can enhance ODL quality.


We show that an extremely high-priced product featured among more moderately priced prod- ucts within a catalog can increase the reservation price for a moderately priced target product as well as the category as a whole. We investigate how this increase is influenced by the degree of relatedness between the extreme-priced product and the target as well as the situational and temporal proximity (contiguity) in their presentation. Consistent with our conceptualization, we find that the presence of an extreme cue leads to greater changes in target reservation price when the extreme-priced referent and target are more related and are contiguously presented. Furthermore, the impact of an extreme-priced product's relatedness on reservation price ap- pears to be greater when the contiguity between the extreme-priced product and the target prod- uct is high versus when it is low.


A molten salt strategy with SnO2 nanoparticles as precursor in a mixed molten salt system (NaCl + Na2CO3) was used to prepare tin-based oxide microstructures with various morphologies, including porous hollow, bimodal mesoporous and solid core–porous shell structures in a large scale. The morphology of the as-synthesized products exhibits a strong correlation with the weight ratios of NaCl/Na2CO3 in the mixed solvent. With NaCl:Na2CO3 = 1:1, the liquefaction of eutectic salt and the reaction between SnO2 nanoparticles and Na2CO3 would happen simultaneously, which allows formation of the porous hollow particles by Ostwald ripening and decomposition of Na2CO3. As the weight ratios of NaCl to Na2CO3 are increased to 2:1 and 4:1, the morphology of oxides is changed from porous hollow structure into bimodal mesoporous structure and solid core–porous shell structure, respectively. The morphologies of as-synthesized nanostructures are determined by the release rate of CO2 from solvent decomposition and the aggre...


1. Kaufmann & Wu (2002, EPSL 197:1-10) showed that if the ice history is known, then the current method of detecting lateral changes in lithospheric thickness with 1-D earth models by dividing RSL data into regional subsets, can give accurate estimation only if there is no lateral change in mantle viscosity below the lithosphere – otherwise the inferred lateral variations in lithospheric thickness can only be estimated qualitatively. Since both conditions are not met here, it is unclear how accurate are the estimated lithospheric thicknesses. In any case, the paper should include a discussion of this important point. This important point raised by the reviewer is included in the discussion and conclusions of the revised manuscript.


Earlier studies demonstrated a correlation between diurnal bronchial variability and bronchial responsiveness (BR) in asthmatic patients. However, since the most severe bronchial obstruction tends to occur from midnight to early morning, diurnal bronchial variability might underestimate within-day bronchial variability. This study was undertaken to reevaluate the correlation after assessing more precisely the within-day variability of bronchial caliber in 43 children with episodic asthma (23 boys, 20 girls), aged 8-12 years. Seven FEVl measurements were made every 4 h between 1O:OO and 1O:OO for 2 consecutive days. The coefficient of variation (CV) of the last six FEVl was defined as the amplitude. Just after measurement of FEV, at 1O:OO on day 2, measurements of BR to house-dust allergen, histamine, and 7-min free running were made in 14, 14, and 15 patients, respectively. The BR was expressed as the percent change in FEV, from the baseline value in housedust inhalation and running challenges, and as the provocative concentration causing a 20% fall in FEVl (PC,), transformed into a logarithmic scale, in histamine challenge. There were significant correlations between CV [mean (SD), 8.1 (5.3)%] and BR to house-dust [mean (SD), -19.0 (11.8)%] (r= -0.663, p c 0.01), and between CV [mean (SD), 7.4 (5.5)%] and histamine PC20 (geometric mean, 0.38 mg/ml) (r = -0.661, p = 0.01). There was a marginally significant correlation between CV [mean (SD), 6.4 (3.7)%] and BR to running [mean (SD), 28.5 (16.6)%] (r = -0.496, 0.05 cp < 0.1). These re


We read with interest the study performed by Puskarich et al (1) as recently published in your journal. Puskarich et al observed no change in mortality with each hour delay in antimicrobial administration in patients with septic shock. This finding is both intriguing and surprising, as Kumar et al (2) earlier found each hour of delay in antimicrobial administration to be associated with an average decrease in survival of 7%. Several important differences between these two studies can and should be taken into account for correct interpretation. First, Kumar et al included 2700 patients with septic shock, whereas the study by Puskarich et al included only 291 patients. Second, of all patients analyzed in the study by Kumar et al, 78% had a pathogen isolated, twice as high as the number of patients in which infection was confirmed microbiologically in the study by Puskarich et al. Third, the reported mortality rates in the two studies was strikingly different (56 and 19% in the study by Kumar et al and the study by Puskarich et al, respectively). Thus, the investigated populations are quite different, which may be responsible for the different findings. Taking these aspects into account, we may need to realize that the study by Puskarich et al probably was underpowered for showing beneficial effects of timely antimicrobial administration in septic shock. Indeed, the study by Puskarich et al was executed in the "lower" part of the observational time to antimicrobial administration–mortality risk curve (2). Although Puskarich et al claim that they performed a prospective study, their study was not more than a secondary analysis of a previous study with other end points. The original power calculation was insufficient for the present analysis. The study by Kumar et al convinced many of us to early initiate antimicrobial administration in case of septic shock (3, 4). We think that the study by Puskarich et al at best will stimulate other researchers to perform properly designed and wellpowered studies in the future to elucidate time-related effects of antibiotic treatment in patients with septic shock. The authors have not disclosed any potential conflicts of interest.


Language style matching (LSM) offers promise as an unobtrusive measure of synchrony between members of conversational dyads, but no studies have explored key questions related to LSM in developmental context. We examined LSM in young children's (N = 87, Mage = 54.63 months) interactions with caregivers versus experimenters, and evaluated links between LSM and expressive vocabulary. LSM was significantly higher among caregiver–child than experimenter–child dyads and was positively associated with children's expressive vocabulary.


Abstract The effects of day length on main stem growth, flowering, morphology of flower clusters and seed-set were examined in three buckwheat cultivars Shinanonatsusoba (summer eco-type), Miyazakizairai (autumn eco-type) and BLO 1999 (a long cluster line which usually develops DM clusters at Kade Research Ltd., Canada). Long-day treatment prolonged the stem elongation period, elevated the first flowering node, delayed the first flowering day, increased the numbers of nodes, flower clusters and flowers on the main stem, and decreased the increase rate of flowering-cluster number, the number of seeds and the seed-set ratio on the main stem. It also increased the frequency of DM clusters, the length of the flower clusters and the number of sub-flower-clusters per cluster in Shinanonatsusoba and Miyazakizairai as well as in BLO 1999. The effects of day length varied among the growth parameters and there were three types of responses to day length. The difference between the summer and autumn eco-type cultivars in the responses to day length was elucidated in four groups of parameters; (1) main stem elongation; (2) first flowering node and first flowering day; (3) increase rate of flowering-cluster number on the main stem; and (4) the number of seeds and seed-set ratio.


BACKGROUND: A history of anaphylaxis after transfusion of immunoglobulin A (IgA)‐containing blood products in selective IgA‐deficient (sIgAD) patients can be a major problem, particularly in emergencies, when large quantities of blood products are required.


Digital technologies in modern realities are an integral component integrated into all spheres of human activity. Digitization is becoming the most important factor in the economic growth of any state and a new, innovative way of development of any society . Digitization is the newest reality of the advanced countries of Europe and the whole world, therefore, also of Ukraine, which has chosen the European vector of development . The new digital reality presents legal practice and science with many fundamentally new tasks related to the development of effective tools and models of legal regulation of various spheres of social life (in particular, in the sphere of combating crime). On the other hand, digital reality has caused the emergence of new forms of crime – cybercrime, information fraud, a significant number of cyberattacks on enterprises and institutions, which requires counteraction by law enforcement agencies, study and research of this phenomenon. Digital information (as an integral attribute of modern crime and the activities of criminal justice bodies) determines the prospects for the development of legal science, in particular criminalistics, which is at the forefront of the fight against crime in the realities of martial law, digitalization of society and the active use of digital technologies in various spheres of human activity.


The present invention is soy sauce process for the preparation of the using amylolytic enzyme comprising a carbohydrate binding module.


In a communication system utilizing an orthogonal frequency-division multiplexing, an apparatus and method for transmitting and receiving channel quality information for the subcarrier from the terminal to the base station. In a wireless communication system to service by dividing the entire frequency band into a plurality of sub-carriers, a method for transmitting channel quality information, measured channel quality information for each band of adjacent sub-carriers of a preset number step and, among the values, for selecting and transmitting to generate a measured value for at least one band as absolute CQI with corresponding band indexes, by the generated absolute CQI, a band of a predetermined number When the steps to measure the channel quality information, of which, for generating a differential CQI by previous channel quality information and each comparator of the selected measurement value of the selected band band for the selected bands, differential and transmitting it.


The number of houses at risk of wildfire continues to increase around the world and researchers continue to search for ways to minimise loss. This study examines the determinants of house damage in 28 forest fires from New South Wales, Australia between 2001 and 2009 (309 houses lost or damaged), and is notable for the large number of fires, the use of undamaged controls and the statistical methods that assist the isolation of independent effects on house damage. We focussed on factors in the immediate vicinity of the houses since this zone is where differences between damaged houses and neighbouring controls must occur. A range of spatial measures of vegetation, nearby buildings, waterbodies and topography were derived for each house from Google Earth and Geographic Information Systems data. Principal component analysis was used to select a set of predictors that best represented the variation in these measures. The selected variables were applied to a generalised additive mixed model analysis to derive the best and supported alternative models to predict house damage. The best model contained positive effects of vegetation cover in the garden and slope and negative effects of distance to the nearest building and distance to the nearest waterbody. Although this model explained only 15% of variation in house damage, the difference in predicted probability between a best‐case and worst‐case house was 0.47 suggesting that risk could be effectively mitigated by providing a water‐source, keeping the garden cover low and maintaining separation between houses.


Unacclimated and cold-acclimated rats were exercised for 3 h, 5 h, or 9 h in a cold room maintained at 1.7 °C. The cold-acclimated rats tolerated these exercise periods, but two-thirds of the unacclimated rats died during 9 h exercise. In red and white muscle the intermediate exercise interval (5 h) induced significantly greater increases in the activities in muscle of creatinephosphokinase and glycolytic enzymes of unacclimated rats, while during 9 h exercise enzyme activity declined in muscles of unacclimated rats and increased in cold-acclimated ones. The rise in serum enzyme activity during exercise was consistently greater in unacclimated than in cold-acclimated rats. Apparently the reduction in exercise tolerance was associated with and may have been in part due to loss of enzyme content and activity in muscles. Collectively, these and other biochemical responses suggested that homeostatic mechanisms had been exhausted in the rats dually stressed by cold exposure and exercise. Except for the activit...


Every country adopting individual pension accounts has encountered significant problems of one sort or another. The authors of this
 Policy Forum
 argue that these problems arise at each stage of the retirement saving process: participation and contribution, asset accumulation, and withdrawal. The problems that have been encountered at each of these stages indicate that more work is needed both in practice, to make accounts work better, and in research, to achieve better alignment between economic theory and observed behavior.


HYPERTHYROIDISM, nodular goiter and other types of thyroid disease are more frequently found in women than in men. Goiter, also, often becomes strikingly manifest during puberty, pregnancy and the menopause. This apparent relationship between ovarian function and thyroid pathology has been studied by many investigators. Unfortunately the results have been conflicting. Some have reported that ovarian hormones depress thyroid function (Franck, 1937; Gardner, 1949; Heyl et al., 1934; Karp and Kostkiewicz, 1934; Kreitmar and Sieckman, 1939; Miiller and Aeppli, 1949); others, that ovarian hormones increase thyroid activity (Andersen, 1935; Chouke et al., 1935; De Amilbia et al., 1936; Desclin and Ermans, 1951); and still others have observed no distinct influence upon thyroid structure and physiology (Arnold et al., 1938; Paschkis et al. 1948). A few reports have indicated that estrogens both stimulate and depress thyroid function, depending upon the dose and period of administration (Freudenberger and Clausen...


Monodisperse hydrophobic spherical CaCO3 particles were prepared by carbonation in the presence of dodecyl dihydrogen phosphate(DDP).The surface property of CaCO3 particles was transformed from hydrophilic to hydrophobic when the mass ratio of DDP to CaCO3 changed from 0 to 2%.X-Ray diffraction(XRD) patterns showed that the crystal form of CaCO3 particles was turned from calcite to aragonite with increasing the dosage of DDP in the reaction.FTIR spectra indicated the existence of the alkyl groups from the DDP in the products.When the mass ratio of DDP to CaCO3 was 2%,the active ratio reached 99% and the contact angle of modified CaCO3 particles was 120.43°.Simultaneously,the effects of the reaction temperature and the dosage of DDP on the morphology and behaviors of aragonite crystals were discussed.When the schematic illustration on the formation process of hydrophobic spherical CaCO3 particles was discussed in the work.When the obtained modified CaCO3 was added into polypropylene(PP),the mechanical properties and processabilities of PP improved greatly.


The present invention is extruded from the forming section consisting of a molding of a raw material supplied to the molding is easy to control the state of the raw material drum and the pressure roller relates to a pellet production apparatus capable of producing a pellet by using a raw material of various kinds as the exhaust relates to various materials in pellet production apparatus that can be produced in a pellet form. The main configuration of the present invention, quantitative feed means for feeding the raw material introduced into the input port; Conditioning unit for heating or supply by molding is easily adjust the state of the raw material when added to water of a raw material to be supplied is installed in the lower part of the quantitative supply means; The forming section, which presses the raw materials for the composition of the atmosphere formed by the exhaust conditioning unit into pellets; Comprising: a cutting edge which is provided at one side of the cutting portion forming the molding material discharged from the forming unit, The molded part forms a cylindrical tubular shape, a plurality of pressure-overflow hole is formed in the side wall, the rotated in a state of being in close contact with the inner wall of the forming drum and the forming drum which is rotated by the driving of the motor supplied to the interior of the forming drum It is implemented to include at least one pressure roller that presses a material to push the pressure discharge of the forming drum alone.


m ilm is a product of an industry whose ultimate goal is obtaining a maximum profit; accommodations made in pursuit of such profits often stand in the way of historical accuracy. Thus, it is surprising to find a film such as Barry Levinson's Avalon, the third in his series of semi-autobiographical "Baltimore pictures," which, in the spirit of Diner (1982) and Tin Men (1987), transcend economic accommodations to render a highly accurate portrayal of American life-in this case, the life of an American Jewish immigrant family. Because a film such as Avalon is so rare, it merits close study of the historical insights it provides.


Aim To establish an HPLC determination method of hesperidin in muxiangshunqi pill.Methods The analytical column was C_1_8. The mobile phase was Methanol: 0.2%-phosphoric acid ( 21∶79) at the detection wavelength of 283 nm.Result Linearity range was 0.208~2.08 μg(r=0.9997) , Y=22602000X–2459.1;The average recovery was 101.8% ( n=6) woth RSD=1.6%.Conclusion The method can be used in the quality control of sizhixiangfu pill.


Abstract Soybean DAS‐44406‐6 expresses 5‐enolpyruvyl‐shikimate‐3‐phosphate synthase (2mEPSPS), conferring tolerance to glyphosate‐based herbicides, aryloxyalkanoate dioxygenase (AAD‐12), conferring tolerance to 2,4‐dichlorophenoxyacetic acid (2,4‐D) and other related phenoxy herbicides, and phosphinothricin acetyl transferase (PAT), conferring tolerance to glufosinate ammonium‐based herbicides. The molecular characterisation data and bioinformatics analyses did not identify issues requiring assessment for food/feed safety. The agronomic and phenotypic characteristics revealed no relevant differences between soybean DAS‐44406‐6 and its conventional counterpart, except for pod count, seed count and yield. The compositional analysis identified no differences requiring further assessment, except for an increase (up to 31%) in lectin activity in soybean DAS‐44406‐6. Such increase is unlikely to raise additional concerns for food/feed safety and nutrition of soybean DAS‐44406‐6 as compared to its conventional counterpart and non‐GM reference varieties. There were no concerns regarding the potential toxicity and allergenicity of the three newly expressed proteins, and no evidence that the genetic modification might significantly change the overall allergenicity of soybean DAS‐44406‐6. Soybean DAS‐44406‐6 is as nutritious as its conventional counterpart and the non‐GM soybean reference varieties tested. There are no indications of an increased likelihood of establishment and spread of occasional feral soybean DAS‐44406‐6 plants, unless exposed to the intended herbicides. The likelihood of environmental effects from the accidental release of viable seeds from soybean DAS‐44406‐6 into the environment is therefore very low. The post‐market environmental monitoring plan and reporting intervals are in line with the intended uses of soybean DAS‐44406‐6. In conclusion, the GMO Panel considers that the information available for soybean DAS‐44406‐6 addresses the scientific comments raised by Member States and that soybean DAS‐44406‐6, as described in this application, is as safe as its conventional counterpart and non‐GM soybean reference varieties with respect to potential effects on human and animal health and the environment in the context of the scope of this application.


 Abstract—This paper illustrates the event-oriented Behavioral Pattern Analysis (BPA) modeling approach in developing an Air Traffic Control System ATC). The Event defined in BPA is a real-life conceptual entity that is unrelated to any implementation. The major contributions of this research are developing the Behavioral Pattern Analysis (BPA) modeling methodology. And the development of an interactive software tool (DECISION), which is based on a combination of the Analytic Hierarchy Process (AHP) and the ELECTRE Multi-Criteria Decision Making (MCDM) methods.


We investigated the absolute concentration of N–acetylaspartate (NAA) in the thalamus, anterior cingulated cortex (ACC), and prefrontal cortex (PFC), in chronic pain patients by proton magnetic resonance spectroscopy (1H–MRS). 1H–MRS was performed with a 1.5T MR system on a voxel in the thalamus, ACC, and PFC bilaterally, in 18 chronic pain patients and 15 normal control subjects. We measured the absolute concentration of NAA using a LC–Model. The patients whose NAA concentration in the ACC or PFC decreased significantly, compared to the mean NAA concentration of the normal control subjects, needed psychological approach. 1H– MRS suggest that NAA concentration in the ACC or PFC seems to be associated with the necessity of psychological approach. 1H–MRS may serve as a useful non–invasive tool for evaluating neural activity of thalamus, anterior cingulated cortex, and prefrontal cortex in chronic pain patients.


To ensure the quality of bottled mineral water, selection of mineral water sources, controlling of algae and mildew and calcium carbonate precipitation technology and equipment are key procedures. The authors made some suggestions.


The mean-variance scaling relationship known as Taylor's power law has been well documented empirically over the past four decades but a general theoretical explanation for the phenomenon does not exist. Here we provide an explanation that relates empirical patterns of temporal mean-variance scaling to individual level reproductive behavior. Initially, we review the scaling behavior of population growth models to establish theoretical limits for the scaling exponent b that is in agreement with the empirically observed range (1 5 /b 5 /2). We go on to show that the degree of reproductive covariance among individuals determines the scaling exponent b. Independent reproduction results in an exponent of one, while completely correlated reproduction results in the upper limit of two. Intermediate exponents, which are common empirically, can be generated through the decay of reproductive covariance with increasing population size. Finally, we describe how the link between reproductive correlation and the scaling exponent provides a way to infer properties of individual-level reproductive behavior, such as the relative influence of demographic stochasticity, from a macroecological pattern.


One variant restriction sites of Luxi cattle H-FABP, HaeⅢ-RFLP in intron 2,was found by PCR-RFLP method.The association between genotype markers and the corresponding marbling and tenderness traits were analyzed by using general linear model at the level of DNA.The result was the B allele of Luxi cattle H-FABP gene intron 2,especially homozygous BB showed a highly significant positive effect on Warner-Bratzler Shear force of beef tenderness traits(P0.05);AA,BB and AB genotype no differ significantly effect on marbling.


According to the Centre for Monitoring Indian Economy, India is one of the well resourced countries with plenty of raw materials. Since the raw materials are easily available, the human requirement also increases which leads to mass production of waste. Waste materials thus produced can be reverted into resources by recycling process. This recycling process can be done by proper sorting of waste into various categories like degradable and non-degradable wastes by human efforts. Recycling contamination also occurs when harmful wastes are mixed together. This paper comes up with an idea of smart dumpster monitoring and clearance system which sorts the garbage using Machine Learning based image classification. After sorting and disposal of waste, it notifies the municipality waste collector through Wi-Fi module over the internet about the bin level for collection of garbage before the bin overflows.


Today, the men are leading an high-technical society upon the continued industrial developments. And changing of eating-habits concerned with their increasing incomes have been brought to high consumption of processed foodstuffs. So, lots of geriatric diseases are increasing due to of their unbalanced nutritive conditions. In the other hand, hotel rooms of special grade are suddenly increased by 57.4% than last year for the Seoul Olympic Games. It means that managing difficulty of hotels from now. As one of solution, it seems need to prepare some plans against geriatric diseases which can control by diet. First, Using the computer, we can got all informations what we need for the guest: for their tasties, favourities, health-check general, and so on. It would be possible to serve perfect menus by guest`s personal specialities. Second, organizing the section of $quot;Menu Research Part$quot; for study of menus against the geriatric diseases, of using natural foods efficiently are requested. Third, full technical informations are required to refer and develop the new trends to international flew. Their own styles of each hotels, continued cooking studies, investment and development for the new food materials, all above are really requesting as the best plan of $quot;Food Sales Strategy$quot;. I am sure of all will lead and help for Hotel Business between competitions and for the national health also.


Describes a user‐friendly decision support tool to select near optimal containers for specific manufacturing scenarios relative to all the constraints associated with the use of the container. Guides the user through a dialogue to input constraints and scenario‐specific information. Shows how the decision support tool iterates between an expert system and a simulation model, to produce a near optimal container with respect to internal and external dimensional requirements. Explains the methods by which the system is tested and validated in a realistic environment. Discusses future research directions.


The goal of this study was to investigate the factors that influence how consumers continue to use, and how frequently they use, internet banking in Australia. Patterns of continued use and frequency of use of internet banking have been neglected as most of the existing studies focus on either consumer adoption or acceptance of internet banking. However, in comparison to new customer acquisition, measures of continued and frequent use of internet banking are related to a cost-effective marketing strategy aimed at retaining customers. This study addresses a gap in existing literature which requires the application of more integrated theory testing and the identification of factors that influence the continued and frequent use of internet banking. The study sets out to develop a framework based on theoretical models related to the acceptance of technology and diffusion of innovations theory that encompasses technology, channel, social and value for money factors as predictors in the identification of influential factors for consumers and their continued and frequent use of internet banking.


Peer worker roles are being introduced in mental health services in the UK and internationally, to support individuals in their recovery. There is substantial qualitative evidence that demonstrates benefits at an individual level and some evidence of impact on service use and costs, although there are currently few high-quality randomised controlled trials supporting these findings, especially from the UK. A growing body of research indicates that careful consideration of organisational issues regarding the introduction of peer worker roles – the distinctiveness and shared expectations of the role, strategic alignment, organisational support – might maximise their impact. Properly supported and valued peer workers are an important resource to the multidisciplinary team, offering experiential knowledge and the ability to engage patients in their treatment through building relationships of trust based on shared lived experience.