text:
SC712U - Smeg 27-Inch Linea Design Electric Multifunction Wall Oven - Stainless Steel
Freight Shipping
Smeg 27-Inch Linea Design Electric Multifunction Wall Oven - Stainless Steel
The ultra-modern look of the Smeg 27-Inch Linea Design Electric Multifunction Wall Oven (SC712U) features a refined stainless steel finish with unique Stopsol® glass with a "supersilver" reflective coating. The Stopsol® coated glass is the same exact glass used by architecture and engineering specialists for its thermal rejection and reflective qualities. The oven uses two (2) ergonomically-designed knobs and a unique backlit electronic transparent display that seamlessly blends into the front. Below, sits a triple glazed door that is removable, has an attractive slim-line handle, and also features an easily removable and easy-to-clean inner door glass. Inside you'll find a powerful convection fan, lights, a rotisserie motor, and four (4) rack and tray guides.
This multifunction electric wall oven has a quality matched by few and also has an array of impressive functions. With 12 cooking modes, including: top and bottom heat, bottom heat, intensive broil, broil, convection broil, convection with top and bottom heat, convection with bottom heat, European convection, European convection with top and bottom heat, defrost, ECO (fast preheat), and bread proofing, this electric oven is capable of handling any baking, broiling, or convection task it encounters. The oven also features stay clean liners as well as an automatic door-activated oven shut-off. Included with the oven are one (1) baking tray, one (1) broil pan with broiler rack, two (2) wire racks, and one (1) rotisserie kit for deliciously healthy cooking.
Reflective Solar Control Finish:
Luxurious stainless steel and Stopsol® reflective glass cover the oven front that also features a transparent digital display for a flawlessly attractive look12 Cooking Modes:
An impressive list of cooking modes features cooking capabilities across a very wide range of purposes from true European convection to bread proofingRotisserie Kit Included:
For the juiciest, most flavorful foods, this oven comes with a built-in rotisserie motor as well as a rod assembly and drip tray
- Model: SC712U
- Brand: Smeg
- Capacity: 3.0 cu. ft.
- Exclusive Linea Design
- Stainless steel finish w/ Stopsol® "Supersilver" glass
- True European convection
- 12 cooking modes
- Electronic multi-feature display
- Ergonomic backlit transparent controls
- Automatic door-activated oven switch-off
- 1900-watt max bake element
- 1750-watt max broil element
- 2750-watt max convection element
- Warranty: 1 year
- Smeg 27-Inch Linea Design Electric Multifunction Wall Oven
- Triple glazed door with heat reflective inner layer
- Quickly removable, easy-to-clean inner door glass
- Air cooled door
- Stay clean liners
- One (1) baking tray
- One (1) broil pan w/ broiler rack
- Two (2) wire racks
- One (1) rotisserie kit
- Input Voltage: 240/208 V/60 Hz
- Power: 2750 W/15.4 - 13.2 A
- Interior Dimensions: 12.19" H x 22.31" W x 16" D
- Cutout Dimensions: 22.88 - 22.94" H x 26 - 26.19" W x 22.06" D
- Overall Dimensions: 23.44" H x 27.5" W x 22.25" D
Interior Dimensions:
Cutout Dimensions:
Overall Dimensions:
You may download a product owner's manual below:
**Please note, Adobe Acrobat Reader is required to view pdf files
Usually Ships in 3 - 4 Business Days
This item ships via Freight Line Carrier Delivery times related to this ship method are usually between 3 to 7 business days once the item leaves the warehouse. We will forward tracking information to you once the product leaves our warehouse. The shipping company will contact you to arrange a delivery appointment as a delivery signature is required. All deliveries will occur Monday through Friday. Order must be fully processed by 12pm CST to be eligible for "Guaranteed Same Day Shipping." Orders processed after that time may ship out the following business day.Freight Line items will be delivered to the first ground floor exterior door available provided there are no stairs to ascend or descend. If you require inside delivery you will need to select the premium shipping option in checkout. To determine if the item is eligible for premium shipping please add it to your shopping cart and view the shipping options drop down box. Please contact our customer service department with any questions related to shipping at (800) 297-6076, M-F, 8am to 5pm CST.


text:
Latest from R.C. Sproul
Are We Too Concerned with Demons?
from R.C. Sproul Sep 17, 2012 Category: Articles
In recent years, there has been a renewal of interest in the work of Satan. Keep Reading -
Is Election Unfair?
from R.C. Sproul Sep 14, 2012 Category: Articles
The teaching that God chooses some people out of the mass of fallen humanity to be saved and not others raises the objection that God is not fair. Keep Reading -
Help Us Reach the World through Digital Media
from R.C. Sproul Sep 12, 2012 Category: Ministry News
Our forward-thinking use of communication tools enables us to reach as many people as possible. Can you help us use digital media for God's glory? Keep Reading -
Principles for Voting
from R.C. Sproul Sep 10, 2012 Category: Articles
When you enter the voting booth, don't leave your Christianity in the parking lot. Keep Reading -
Announcing our 2013 National Conference
from R.C. Sproul Aug 27, 2012 Category: Ministry News
On February 21-23, 2013, Ligonier Ministries will be hosting our annual conference in Orlando, Fla. Alistair Begg, Sinclair Ferguson, Robert Godfrey, Steve Lawson, R.C. Sproul Jr., Cal Thomas, and Ravi Zacharias will join me as we consider the theme "No Compromise: Standing for the Truth of God's Word." Keep Reading -
How Should Protestants Relate to Roman Catholics?
from R.C. Sproul Aug 27, 2012 Category: Articles
I am happy to make common cause with Roman Catholics on social issues, but we have no common cause in the gospel. Keep Reading -
The Grounds of our Justification
from R.C. Sproul Aug 20, 2012 Category: Articles
At the very heart of the controversy in the sixteenth century was the question of the ground by which God declares anyone righteous in His sight. Keep Reading -
The Mission of the Church is Eternal
from R.C. Sproul Aug 15, 2012 Category: Articles
The mission of the church is eternal. Its origin is in eternity and its destination is eternity. God's plan of redemption for this fallen world was not an afterthought or an expression of a plan B. Rather, before the world was even created, in all eternity God the Father, God the Son and God the Holy Spirit had a covenant among themselves that we call the Covenant of Redemption. Keep Reading -
Jesus' Prayers Keep You From Stumbling
from R.C. Sproul Aug 01, 2012 Category: Articles
What was the difference between Judas and Peter? Jesus did not pray for Judas. Keep Reading -
Is It Just That in Adam All Die?
from R.C. Sproul Jul 18, 2012 Category: Articles
How is it just that all humanity is born into sin because of Adam's fall? Read R.C. Sproul's answer to this question. Keep Reading

subset: commoncrawl


text:
order by phone... 1-800-828-4548
order by item number...add items to my cart
Browse more:
Rich Art's high-quality Dust Free Powder Paint is a great value. Simply mix it with water to create your own vibrant tempera — in the exact amount you need for the project at hand.
Hint — click a thumbnail to enlarge.
Please select one of your Lists or create a new List.
Your cart is currently empty.
® Rich Art is a registered trademark.


text:
Dedicated by the Jacobs and Chill Families in Memory of Harold and Pearl JacobsDora Bas Rivka Silver O'H
Psalms - Chapter 86
Rabbi Chaim Brovender
David's "Wish List"
A Psalm of David, this one is called tefilla, a prayer.
David asks G-d to hear his prayer, because he is poor and destitute. (The Radak says that although David had significant funds to his name, he was unable to access them while on the run from his enemies. This forced him to survive on help given him in secret by members of his Tribe and others.) David asks G-d to protect his soul because he is a pious person who places his trust in G-d. David asks for favor from G-d because he calls out to Him all day long. Finally, David asks G-d to gladden him because he dedicated his soul completely to G-d.
David says that G-d is all-good and the source of forgiveness. He grants kindness to people - even the wicked - when they cry out to Him. And so, David hopes that G-d will heed his prayer. He is confident that G-d will answer him, as he is crying out on his "day of trouble."
There's no other "god" - only He has any power. (The Radak says that the Heavenly spheres in their orbits only do what G-d told them to do.) All the nations that G-d made will eventually recognize and serve only Him. Only G-d can make the wonders of creation.
David asks G-d to instruct him so that he will know how to walk in His truth (Torah) and dedicate his heart to G-d's service. When this happens, he will praise G-d and thank Him for it wholeheartedly. G-d's kindness towards him has been great, David says, and He saved David's soul from the depths. (The word for grave - sheol - could also be read Shaul - King Saul, who sought to destroy David.)
Many enemies have persecuted David (Rashi specifies Doeg and Achitofel); they want to corrupt and destroy him. G-d, however, is merciful, compassionate, slow to anger, and full of kindness and truth. (This is a paraphrase of the traits of G-d found in Exodus 34:6.) David asks G-d to give him strength to endure his enemies' attacks; he is G-d's servant just as his mother was G-d's maidservant.
David ends the psalm with a request for a sign that his sin has been forgiven. When his enemies see this, they will be embarrassed of their attempts to harm him. When He does this, G-d will have comforted David.


text:
Zoo Season and Hours: Check the Event Calendar for Special Events
2013 season: April 1 through October 18 from 10 a.m. to 5 p.m. Daily
Put on your costumes and trick-or-treat your way through the decorated Zoo!
Load your treat bag with goodies from various vendors and booths.
Watch Dr. Slime, the mad scientist, put on a mysterious, scientific show!
Ticket price includes Zoo admission, train and carousel ride, Dr. Slime Show and trick-or-treating. Zoo Members and the General Public: $7 discount tickets available through October 18th. October 19th and after tickets are $9
Call (989) 759-1408 for your tickets today!
JEvents v1.5.0 alpha2 Copyright © 2006-2008


text:
IWA Revolution Creative Team WWE/IWA/RTE Originally Posted by VanHooliganX Friendly reminder that Ashley is fucking awesome.
Houston Born, Houston Bred... When I die, I'll be Houston Dead! E-Fedding Career Jeff Jarrett (WWE Fantasy Fed) Kay One & Fler (IWA)
View Tag Cloud
Forum Rules
© 2011 eWrestlingNews, All Rights Reserved.


text:
Roots to Roofs Spring 2013
Read all about the tips, tricks and trends in the valley concerning gardening, home remedies. This quarterly guide is packed full of everything to do about the household. There is also featured listings and agents for the perspective home buyers and sellers.
Would you like to comment on this article?
Only online subscribers may comment on articles. Click here to see how you can subscribe.
Already a subscriber, please log in
Note: Some articles do not accept comments at all.
• Rain expected this afternoon, although it may be freezing (10857)
• Several burglaries reported downtown (5700)
• Morning snow impacting school districts; missing trio located (4810)
• McMinnville man injured in crash (3978)
• Where to watch the Wildcats (3034)
• Two-alarm fire destroys Amity home (2785)
• Bank robbing family featured tonight on ABC's 20/20 (2324)
• Arrest made in 7-Eleven armed robbery (2153)


text:
That is pretty cool, I personally like the commercial painting services in Phoenix, AZ. I pretty much just love everything about AZ actually, and it is nice and warm down there.
Leruas does stand out because of the best tamales anywhere. The enchiladas are great and the prices are very good. Numerous combination plates equal great deals.
This place is awesome, for all your mexican food needs. The drive through option is heads above your typical drive through mexican. The dinner plates are very tasty as well, although to onion heavy.
Where this place really shines though, are the breakfast plates. You have not lived until you have had the red chili pork tamales with fried eggs on top!
left out a word, should have said ribs are very meaty and not too fatty
Great place for a steak!!! Fabulous food & atmosphere with live music on the weekends.
Amazing place with the perfect atmosphere to just unwind. The bartenders are fast friendly and work hard to make sure you keep coming back. The regulars are friendly and seem to avoid drama at all cost.
Love their steak and beans, and salads...never have enough room for dessert. Servers have been friendly. We enjoy walking around the trail dust town, and shop a bit...don't visit much anymore since moving to a rural area SE of Tucson...have to drive to Sonoita for a decent steak now :D
KJ Sean is by far one of the best KJ's I have ever met. He has the most diverse and comprehensive collection of song choices and provides a fun experience.
The Venue, Salty Dawg, while a bit congested at times, provides friendly and fast service.
TMW is a must see whether its at the Salty Dawg or a street corner!
Great service! Friendly staff beef stroganoff and fish is awesome wings are all drumsticks 13 per order! Great dive where there's something todo everyday of the week especially now since footballs here!
No new reviews so i thought I would post one.
Friday has perennial 80's and G. Cover charge and packed. Saturday night ; no cover smaller crowd and sometimes very good bands (Giant Blue, etc). Definitely the night to go. Mixed crowd with many older people looking for hookups (well it's true). Drinks are very reasonable for Foothills, food good. Bartenders are nice and fast
This restaurant has the best vegetarian Vietnamese selection in Tucson--very extensive. Prices range from more expensive than I would expect to very cheap. Luckily their excellent baguette sandwiches are only $4.50 and are delicious.
M&L Airport Inn Bar and Grill come check it out! New bold and dynamic atmospere that will stimulate your mind. The new remodeled look is updated and has two new beautiful patios and a brand new kitchen opening soon!
Great bar great people friendly staff new hot bartenders ! Cant wait to see the finish project!
Caliente DJ has a great variety of music from Old school to the new hits and even reggaeton and cumbias! He has the party lights and he's system sounds great! The music he spins makes you wanna dance! =)
I moved here from San Francisco and have had a hard time finding really good Chinese food. BirdsEye frozen vegetables tossed with plain chunks of tofu in a salty brown sauce doesn't do it. I can't believe it took me this long to try Lotus Garden, but it's the real thing--snow peas and carrots were lightly cooked so they were bright and had a bit of snap, the sauce relied on the flavors of its ingredients and not salt for its punch, the tofu was sliced thin and lightly fried for texture and flavor, and the shrimp were huge. My new go-to Chinese place.
Very good food and an excellent selection! I'm glad I live close by. P.S. I spoke Spanish and was answered in English!
Agree that it is a great addition to the Oro Valley restaurant scene. My son-in-law visited from Cambridge MA over the holidays and felt it was a real find. He brews beer at a place called John Harvard's ( yeah it is near the University by the same name) . Lot of great beers and an incredible variety of west-of -the-Mississippi local brews. Food is good brew pub snack food . Not sure what a gastro-pub is, but sense the taste/variety fell a bit short. But this is a place about the 100 + beers, not the food.
I enjoyed the entire experience. Everyone did an excellent job. Only suggestion would be to have more private tables and a little more elbow room. It's a beautiful location and very central.
The strip mall is dumpy, and the interior of Mother Hubbard's doesn't win for style. What they do have is great service, great food, and fair prices. My wife and I have been there for breakfast and lunch. It's pretty much a scratch prep for everything. Their locally sourced and created ingredients are top notch. Food with character!


text:
Chewie on Hoth
If you liked this, you might like these:
- None Found
Incorrect source, offensive, or found a typo? Email us (please put title in subject bar of email so we'll be able to fix). Or do you want to write for Elephant?
{Waylon H. Lewis C Enterprises 2013: Use Rights in perpetuity. Ownership remains with author.}
Diane Ferraro, an only child and Metal Pig, has fancied herself a writer since she can remember. Probably because her imaginary friend told her she was pretty good at it. In
yoga, we call those friends our "higher self." Vacillating between yang and yin, she gets giddy and goes digging in the dirt in equal measure. As a New York-based, worldly-wise executive with fifteen years of experience in fundraising, event planning, publicity, and organizational management, and an entrepreneur leading her own socially responsible communications and growth strategies consulting company, Urban Siren (www.urbansiren.com), Diane is dedicated to advancing the melioration of individuals, communities, and the environment. Looking back on her bio, Diane is a little creeped out that she's been referring to herself in the third person but she's really excited to be a part of the Elephant Journal crew as a contributing trouble maker
writer. Feel free to heckle reach her at firstname.lastname@example.com and Twit with her @urbansiren
22,276 views
18,254 views
10,375 views
7,782 views
5,807 views
5,683 views
5,394 views
5,127 views
4,820 views
4,216 views
3,966 views
3,820 views
3,768 views
3,537 views
3,448 views
374,406 views
148,829 views
130,126 views
105,888 views
100,779 views
97,525 views
97,150 views
95,315 views
85,939 views
73,691 views
68,972 views
67,047 views
63,686 views
60,005 views
59,502 views
1,924,992 views
529,757 views
491,002 views
429,738 views
398,322 views
395,954 views
373,166 views
282,572 views
258,305 views
250,127 views
238,795 views
233,881 views
198,041 views
197,952 views
190,112 views


text:
Spotlight: Member Stories
For some reason I can't edit my old log in, WebMD seems to have lost it. I had emergency bypass surgery 01/13/2006 for 99% blockages of my LAD an...More
Helpful Tips
Tai Chi beneficial as rehab exercise
http://www.ncbi.nlm.nih.gov/pubmed/20503465 This study only did Tai Chi once a week. I would think other rehab was also taking place. More
17 found this helpful
- How hard to exercise in the beginning
- Understanding how diet affects heart disease
- Key to Healthy Arteries
Related News
Related Drug Reviews
- Drug Name User Reviews
Report Problems to the
Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


text:
December 24 – Happy Birthday Bill Otis
You would think that with a last name like Otis, this guy would at least have had an "up and down" career with the Yankees parent club and their farm system. Unfortunately for Bill, his entire big league experience consisted of just four games for the 1912 New York Highlanders (the team's name before they became the Yankees.) He got just one hit in seventeen at bats that year but that one hit came off the immortal Hall-of-Famer, Walter Johnson. He is the only current or former Yankee to be born on Christmas Eve. He's also the only native of Scituate, MA to play Major League baseball. When he died in 1990 at the age of 100, he was the oldest living former MLB player on the planet.
The only other member of the Yankee family to be born on Christmas Eve is this former NL All Star pitcher who was signed by New York in 2011 but only pitched for their Triple A team in Scranton.


text:
Captain America Shield
Show: SternFX
In this video tutorial I'll show you how to create the shield inspired by the movie Captain America without leaving After Effects. The project is based on plug-ins created by Mettle and includes two compositions, one which uses FreeForm Pro and ShapeShifter AE and the other based on the bundled FreeForm plug-in which is included with After Effects from version CS5.
- Products covered:


text:
Eight Sixty
Velvet Burnout Dress
Eight Sixty features a modern collection of trendy prints in colorful palettes. Their tops and dresses feature ruffles and color blocks with fun trims and embellishments that are sure to catch your eye.
- Self: 60% rayon 40% poly
Contrast: 100% poly - Shoulder seam to hem measures approx 34" in length
- Lined
- Adjustable shoulder straps
- Textured print
- Hand wash or dry clean
- Styled with Ash Super Calf Suede Bootie in Black Brushed.
- Styled with House of Harlow Stone Top Multi Skull Cuff in Gold.
- Styled with House of Harlow Resin Pyramid Double Finger Ring in Gold Plated Black Resin.
- Styled with House of Harlow Bone Stack Ring Set in Gold.
- Modeled in size S. See fit guide for model's dimensions.
- Revolve Style No. EIGH-WD227
- Manufacturer Style No. CMA890201


text: Press Leading reporters speak their MIND on Sustainable Meetings in Copenhagen via social media UN World Happiness Report 2013: You should go to Denmark! Good Evening, Copenhagen! Eurovision 2014 on a small island FRESH14 and European Sustainable Events Conference join forces in Copenhagen Cutting edge stellar chefs and World Class Jazz at new CPH venue 'The Standard' Happy Birthday, Little Mermaid! Danish icon is celebrated worldwide The world's most liveable city - Denmark's capital Copenhagen The world's longest Viking shipwreck exhibited in Copenhagen Mission accomplished: The Danish 'Tap Water' EU Presidency shares its legacy Noma will keep changing everything Leading Reporters tweet about CPH Denmark - happiest nation worldwide Eurovision 2014 in Copenhagen FRESH14 & ESEC Conference in CPH Promising Jazz & Food venue in CPH Little Mermaid turns 100 years The world's most liveable city World's largest Viking ship on display EU2012 shares its legacy Noma will keep changing everything VisitDenmark's Press Room Leisure news Business news Photos and videos Event Calendar Feature stories Denmark A-Z Destinations in Denmark News Looking to be inspired Meet the Vikings, go island hopping on some of Denmark's more than 400 islands, taste the New Nordic kitchen, learn more about Danish bicycle culture and get wiser on how the Danish approach to staging MINDblowing meetings... Find these and many more features right here! MINDevent 2013 a huge hit with international meeting planners! Play Video Event calendar Images and videos For images of Denmark take a look at our extensive database. Here you find digital material, such as photos and video, that can be used free of charge when mentioning Denmark as a tourism destination. All pictures are available in hi-res. Vikings Borgen... The Killing... Dark Danish dramas to die for. New Nordic Noir Borgen... The Killing... The Bridge... It's the New Nordic Noir! Borgen... The Killing... Dark Danish dramas to die for. News for the press First name * Last name * Email address * Media * Country * Interests * Leisure tourism Business tourism


text:
Blaenavon man should 'go to London' to find work - Monmouth MP (From Free Press Series)
Get involved: send your pictures, video, news and views by texting FPRESS to 80360, or email us
Report this comment
Monmouth MP David Davies suggests Blaenavon man 'goes to London' to find work
4:44pm Tuesday 8th October 2013 in News
Monmouth MP David Davies talks to Blaenavon couple, teenager Amy Evans and her partner Lloyd Mulry for the BBC programme Week in Week Out
A MONMOUTHSHIRE MP suggested a man should "go to London" to look for work if he couldn't find a job in the town.
David Davies MP visited the World Heritage town as part of tonight's BBC Wales programme "Week In Week Out" looking at the effect of the UK Government's so-called bedroom tax, which encourages people on housing benefit with spare bedrooms to downsize, or face a cut in their benefit.
The programme went behind the scenes with Bron Afon Housing Association, which has 509 properties in Blaenavon but only 23 one-bedroom flats.
The MP, who heads a committee of MPs investigating the effect of the bedroom tax in Wales, claimed the benefit reforms were not working as well here as other parts of the UK, and blamed a shortage of smaller properties for people on benefits to move in to.
The changes to housing benefit has seen a real-terms cut for recipients of 14 per cent for one spare room and 25 per cent for two bedrooms.
Mr Davies said: "These reforms are not working as well in Wales as in London or Birmingham where there is a larger stock of smaller properties."
On meeting teenager Amy Evans and her partner Lloyd Mulry in Blaenavon, the MP said: "The days when we were able to fund people in your situation have gone. You look fairly fit and capable, if I were you I wouldn't spend much longer training on £30 a week. I would be out there looking for work.
"You're not particularly tied to Blaenavon, why not go to London, why stay here if you can't find work here?"
He later said: "Nobody would want anybody not to have a roof over their head."
Housing officer with Bron Afon, Claire Dullea told the programme she could see why the legislation had been introduced, but said: "If we haven't got those one bedrooms available for people to be able to move into then it's not going to happen - and those people left in the three-bedroom houses paying the bedroom tax are really, really struggling."
We contacted Mr Davies for a comment but did not receive a response.
Last month Blaenavon residents challenged the broadcaster Jeremy Paxman to come and visit the town, after he jibed it was not as famous as the Lake District.
Torfaen council even made a video asking him if he will take up the challenge of a visit.


text:
Fidel and religion: Castro talks on revolution and religion with Frei Betto |
Ŕ l'intérieur du livre
43 pages contenant believe dans ce livre
Oů puis-je trouver l'intégralité de ce livre ?
Résultats 1-3 sur 43
Avis des internautes - Rédiger un commentaire
Review: Fidel and Religion: Castro Talks on Revolution and Religion with Frei Betto
Avis d'utilisateur - Tim - GoodreadsI wish that I had been exposed to more of this kind of literature when I was younger. The other side of the story. It is so important in our personal and public education to get outside of the ... Consulter l'avis complet
Livres sur des sujets connexes
Face to face with Fidel Castro: a conversation with Tomás Borge Fidel Castro,Tomás Borge Affichage d'extraits - 1993 |
War, Racism and Economic Injustice: The Global Ravages of Capitalism Fidel Castro Aperçu limité - 2002 |
Autres éditions - Tout afficher
Fidel and religion: Fidel Castro in conversation with Frei Betto on Marxism ... Fidel Castro,Frei Betto Affichage d'extraits - 2006 |
Expressions et termes fréquents
already Argentina asked Batista began believe betto bishops Brazil Brazilian called Camilo Catholic Church Chadli Bendjedid Christ Christians Commander Communist comrades countryside course crimes Cuban Cuban Revolution debt economic election everything example exploitation faith farmers father feel Fidel Castro fighting Frei Betto gave guerrilla hatred Havana hectares human ideas important interest interview Isle of Youth Jesuits Jesus Joelmir Beting killed kind later Latin America Leonardo Boff Liberation Theology lived Marxist masses meeting million Moncada moral movement never Nicaragua organization Party people's percent pesos political poor pope preach priests prison problems religion remember Revolution revolutionary rich Sandinista Santiago de Cuba sectors Sierra Maestra social Socialist society Spaniards spirit struggle talk teachers tell there's things Third World tion tionary told took tortured United who'd workers


text:
Panthers win big in first round
Editor & Publisher
Yazoo County came out a little slow, but it didn't take the Panthers long to get down to business in a 35-14 victory over North Pontotoc in the first round of the playoffs.
Panthers quarterback Michael Collum delivered another stellar performance, rushing nine times for 166 yards and a 96-yard touchdown and completing 5-of-9 passes for 96 yards.
Gerald Lampkin added 10 carries for 64 yards and a touchdown while Aaron Hudson had eight carries for 84 yards and a score.
Panthers head coach Bernard Euell said he was proud of his team's aggressive attack.
"At this stage you have to be able to run the football," Euell said. "We knew going in that this was going to be a very physical game, and our guys delivered what we asked of them."
-------for the rest of the story see The Yazoo Herald printed edition or subscribe to the Digital Edition.----------


text:
Mike and Trina swear by their coffee. He enjoys a "saturated" blend, which is "on the cold side"; she prefers a fine espresso grind that is "warm and thicker."
The St. Petersburg, Fla., couple refuses to drink the caffeinated beverage, which they say is bad for their health. Instead, they use it as an enema. They each have at least 100 coffee enemas a month, 6,000 in all since their addiction began two years ago.
Read more: ABC News


text:
Lean and Mean Bug Killer: Amarok 2.0.1
Amarok's version 2.0.1 kills 33 bugs and, thanks to numerous improvements, needs a lot less RAM.
Besides the bugfixes, Amarok 2.0.1 comes with a dozen changes and improvements, and includes some popular features from Amarok 1.x: sorting collection by composer, the "stop after track" feature in the playlist menu and an automatic recovery option to MySQL embedded server.
Changes in the code have vastly reduced memory size and developers have increased support for MTP devices and iPods, enabling multiple track deletion and status bar notification on copying or deleting tracks on iPod.
A list of changes and bugfixes can be found at Softpedia.com. The source code is available on the KDE Project's FTP mirrors.
Issue 158/2014
Buy this issue as a PDF
Digital Issue: Price $9.99
(incl. VAT)
Tag Cloud
New Mint Minted
Version 16 of the popular Linux desktop reveals new tools, edge-snapping, and performance improvements.
New Worm Attacks Linux Devices
Symantec says Linux-Darlioz burrows in through PHP.
Project Sputnik Gets a Boost
Dell renews its quest for the ultimate developer machine.
Sneaky New Linux Attack Discovered in the Wild
Innovative back door looks like normal SSH traffic.
CeBIT Call for Papers
One of CeBITs most successful forums opens the new year with a new name. The popular Open Source Forum continues in 2014 under the name Special Conference: Open Source. This year, the forum will be bigger and offer a wider range of possibilities for sponsors.
Linus Announces Linux Kernel 3.12
New release offers better graphics drivers and expands filesystem support.
Dark Alliance Reinvents Email Security
New mail protocol will shut out the NSA and prevent snooping on metadata.
DDos Attack Map Charts Denial of Service
A new web application helps users visualize distributed denial-of-service attacks.
Saucy Salamander Gets Legs
Ubuntu 13.10 takes a step toward convergence, with lots of mobility, but Mir only partly here.
Intel and Arduino Create Pi-Like System
Galileo board is targeted to embedded developers and educational institutions.


text:
Advisory: canvas functions can reveal data from random places in memory
Moderately severe
Problem description
There is a flaw in the way that certain canvas functions are handled, that can cause the canvas to be painted with very small amounts of data constructed from random memory. The resulting canvas image can be read and analyzed by JavaScript, so an attacker can get random samples of the user's memory, which may contain sensitive data.
Opera's response
Opera Software has released Opera 9.51, where this issue has been fixed.
Thanks to Philip Taylor for reporting this issue to Opera Software.


text: Winter Elementary/Middle School Defensive and Hitting Clinics Sunday, January 19, 2014 University of Maryland Softball Camps are a great place to improve your softball skills, compete against quality athletes, such as you, and, at the same time, experience elite instruction and development from the coaching staff and players from the University of Maryland. Directions to our Camp Facilities! Click Here! for Directions to The "Bubble" Indoor Facility |


text:
van Es MA, Veldink JH, Saris CG, Blauw HM, van Vught PW, Birve A, Lemmens R, Schelhaas HJ, Groen EJ, Huisman MH, van der Kooi AJ, de Visser M, Dahlberg C, Estrada K, Rivadeneira F, Hofman A, Zwarts MJ, van Doormaal PT, Rujescu D, Strengman E, Giegling I, Muglia P, Tomik B, Slowik A, Uitterlinden AG, Hendrich C, Waibel S, Meyer T, Ludolph AC, Glass JD, Purcell S, Cichon S, Nöthen MM, Wichmann HE, Schreiber S, Vermeulen SH, Kiemeney LA, Wokke JH, Cronin S, McLaughlin RL, Hardiman O, Fumoto K, Pasterkamp RJ, Meininger V, Melki J, Leigh PN, Shaw CE, Landers JE, Al-Chalabi A, Brown RH, Robberecht W, Andersen PM, Ophoff RA, van den Berg LH. Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet. 2009 Oct;41(10):1083-7. PubMed Abstract
What is startling is how multiple genetic and non-genetic triggers of ALS-FTLD share a common neuropathology, i.e., misfolded aggregates of TDP-43, and while it will be a challenge to resolve this enigma, this shared TDP-43 pathology may be an attractive target to focus on for ALS/FTLD drug discovery, regardless of the initiating genetic or environmental drivers of this neurodegenerative disease. View all comments by John Trojanowski
Several questions immediately come to mind, only some with answers.
1. How does this expansion lead to ALS? Preliminary findings suggest that there is either sequestration of RNA or a change in... Read more
1. How does this expansion lead to ALS? Preliminary findings suggest that there is either sequestration of RNA or a change in transcript expression ratios, or both. The protein product of C9ORF72 itself is uncharacterized, and funcbase does not provide an obvious explanation through its predictions.
2. Why does the mutation lead to both sporadic and familial disease? Although we tend to think of familial disease as due to large-effect rare variants and sporadic disease as due to multiple, small-effect variants, this does not need to be the case. One explanation, suggested by Rademakers' group, is that the mutation occurs relatively frequently de novo because the haplotype somehow predisposes to this. However, one does not need to invoke this explanation (although it may well be true), since single, large-effect rare variants will frequently lead to sporadic disease (1), and in the ratio of familial to sporadic described here.
3. Why does the expansion occur at all? Rademakers' group describe the intriguing result that the normal population with the risk haplotype have a larger average number of repeats than those with non-risk haplotypes, suggesting that the risk haplotype may make this region unstable in some way and therefore predisposed to such dramatic expansion.
4. Is it always on the same haplotype? This remains unclear as the two papers disagree on this point.
5. Can we develop a quick screening test? Both papers suggest that a method called repeat-primed PCR could be a quick screening method (2), although Rademakers' group also used Southern blotting, and Traynor's group fluorescent in-situ hybridization.
The finding is another important genetic discovery for ALS and FTD, and adds to the growing list of genes contributing to these diseases. References:1. Al-Chalabi and Lewis: Modelling the effects of penetrance and family size on rates of sporadic and familial disease. Human Heredity 2011. Abstract
2. Hantash et al: Qualitative assessment of FMR1 (CGG) n triplet repeat status in normal, intermediate, premutation, full mutation, and mosaic carriers in both sexes: implications for fragile X syndrome carrier and newborn screening. Genetic Medicine 2010. AbstractView all comments by Ammar Al-Chalabi
PRIMARY NEWSResearch Brief: Latest ALS GWAS Points to Loci on Chromosomes 9, 19
RELATED NEWSCorrupt Code: DNA Repeats Are Common Cause for ALS and FTD


text:
"Ligging aan de belangrijke route US Hwy 1"Beoordeeld door een gast van Hotels.com op 27 feb, 2013
Hotel gekozen vanwege gunstige prijs/locatie verhouding. Ligt buiten downtown Miami. Werd vriendelijk ontvangen door de 2 mensen achter de receptie. Ik verbleef hier 3 nachten. De 3e dag werkte mijn kamer sleutel niet meer. Was verkeerd geprogrammeerd. De kamer zelf was in orde. Schone kamer met voldoende handdoeken. Ontbijt was inbegrepen bij de prijs. Was eenvoudig doch onder de maat. Oud brood, koffie en thee waren lauw. Er was omelet met bacon. Ook lauw maar qua smaak prima. Er waren 2 wifi kanalen. Het kanaal dat ik goed ontving op de kamer kreeg ik geen contact mee. Kanaal waar ik wel op kon was nagenoeg geen ontvangst. Ook kon je maar met 1 apparaat verbinden en dat is zoals ik reis met laptop en smartphone niet handig. Buiten deze kleine verbeterpunten ben ik zeer tevreden over mijn verblijf en zou ik hier zeker weer naar terug gaan.
"Prachtig hotel"Beoordeeld door een gast van Hotels.com op 19 feb, 2013
Na aankomst hebben wij hier de eerste nacht geslapen, uitstekend accomodatie met goede bedden en ontbijt.
"Prachtig Hotel"Beoordeeld door een gast van Hotels.com op 19 feb, 2013
Zeer ruime kamers, heerlijke bedden en een prachtig uitzicht over zee. Voor de mensen die graag de rust en ruimte willen en iets meer willen betalen dan bij een BW Hotel, is dit zeker een aanrader. Bij een volgende verblijf in Miami zal ik hier zeker weer overnachten.
"dicht bij luchthaven en snelweg."Beoordeeld door een gast van Hotels.com op 18 feb, 2013
Wij verbleven in een suite die ruim opgezet is met een mooi uitzicht vanaf het balkon wat smal maar wel heel lang was.Er waren geen zitjes of tafel op het balkon aanwezig.Goed ontbijt wat gratis is evenals de wiffi en parkeren.Zwembad stelt niet veel voor maar is er wel,word niet veel gebruik van gemaakt.Verder een prima hotel.De omgeving doet een beetje rommelig aan maar er is van alles in de buurt zoals restaurants en winkels.
"goed hotel op ocean drive"Beoordeeld door een gast van Hotels.com op 13 feb, 2013
We hadden een standaardkamer deze was goed ingericht en schoon.
Afhankelijk van het hotelbeleid kan voor extra personen een toeslag in rekening worden gebracht.
Bij het inchecken dien je in het geval van incidentele kosten een erkend identiteitsbewijs en een borgsom in contanten of creditcard voor te leggen.
Speciale verzoeken kunnen, indien mogelijk, bij het inchecken worden ingewilligd. Hiervoor kunnen extra kosten in rekening worden gebracht. Speciale verzoeken kunnen niet worden gegarandeerd.
**Mogelijk zijn deze voorzieningen alleen in bepaalde kamers of units beschikbaar. Voor sommige voorzieningen kunnen toeslagen in rekening worden gebracht.
B2 miami downtown offers guests its B indulged® spa suite where they have the option of creating their own spa package with a variety of rejuvenating treatments including therapeutic massages, hot stone therapy, and aromatherapy (advanced reservations may be required). The inviting and tranquil environment allow for the ultimate pampered experience.
De onderstaande recreatieve activiteiten vind je op de locatie of in de directe omgeving. Mogelijk zijn toeslagen van toepassing.
De accommodatie kan de volgende toeslagen en borgsommen tijdens de serviceverlening, bij check-in of bij check-out in rekening brengen:
De bovenstaande lijst is mogelijk niet volledig. Tarieven en borgsommen zijn mogelijk exclusief btw en kunnen wijzigen.
Afhankelijk van het hotelbeleid kan voor extra personen een toeslag in rekening worden gebracht.
Bij het inchecken dien je in het geval van incidentele kosten een erkend identiteitsbewijs en een borgsom in contanten of creditcard voor te leggen.
Speciale verzoeken kunnen, indien mogelijk, bij het inchecken worden ingewilligd. Hiervoor kunnen extra kosten in rekening worden gebracht. Speciale verzoeken kunnen niet worden gegarandeerd.
De Metromover verbindt de AmericanAirlines Arena, de Bayside Marketplace, het financiële district Brickell Avenue, het Miami Art Museum en vele andere centrale attracties. De passagiers kunnen overstappen op de Metrorail om naar het noorden en het zuiden te gaan. De haven van Miami is nabij het centrum. Je vindt er drie etnische enclaves: Little Haiti, Little Havana en Liberty City, de historische Afrikaanse-Amerikaanse wijk.
alle hotels in Miami bekijken"Een goed hotel in down town Miami."
Voor een paar dagen is dit hotel zeker aan te bevelen. De kamers zijn netjes, verzorgd, en schoon. Personeel is behulpzaam en vriendelijk. Het uitzicht op de haven is prachtig.Geverifieerde Expedia gastenbeoordeling
"Miami downtown"
Miami Beach met de wagen op zeer korte tijd en afstand bereikbaar. Bayside Marketplace te voet bereikbaar.Geverifieerde Expedia gastenbeoordeling
"Miami Heat Game"
I recently stayed with a group of people as we drove from Fort Myers over to Miami for a Heat game. I dont think you could have got much closer to the stadium. However, the close proximity is all this hotel really has. I dont think I have ever seen a smaller hotel room in my life. I travel frequently for work across the US and this hands down had the […] smallest rooms. One of the rooms had a very musty odor while the other was fine. There are ice machines on every 3rd floor, so that could be a hassle if you dont land on one of them. The reason is there are 2 elevators that should have been sent down to naples for retirement. These elevators are EXTREMELY slow and like the hotel rooms small. You can fit a max of 6-8 adults and it is very tight. We waited for approx 15 minutes for the elevator to get to our rooms. Then at checkout waited 20 min to see every elevator full that stopped. We ended up taking the stairs from floor 5, which wasnt too bad, just an inconvenience. I dont think I would ever stay here again. It wasnt bad, but definitely not good. Meer infoGeverifieerde Hotels.com gastenbeoordeling
Our stay was average. Our room's landline was dead the whole time we stayed (4 nights) and we notified the front desk but nothing was done. We had to go downstairs every time we needed something. No vending machines anywhere in the hotel even though the hotel room book said there were vending machines on most floors. The first night our room did not […] have washcloths and they never threw away the melted ice nor replaced the plastic bag since the first night we got ice. I do have to say that Stanley front the front desk did a marvelous job but the rest of the service was mediocre. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Full of chaos!"
When we arrived there was no one to pick our baggage and we had to carry them all the way up to our room after having to wait for almost an hour to check in. The rooms are really small plus when we were leaving the elevator broke and there were children stuck inside and it took them like another hour to fix it and we couldnt leave until then(carrying […] our baggage on the stairs from the 10th floor was impossible). Overall i think it is over priced for the service provided. Meer infoGeverifieerde Hotels.com gastenbeoordeling
Staff were awesome! Property was clean and bright. Definitely would stay here again. Only downside is that parking for 1 vehicle should be included with room .Geverifieerde Hotels.com gastenbeoordeling
"need to get valet service together"
unfortunately my colleague and i were very disappointed during a recent work trip to miami. we stayed for the first and last time at the b2 miami. the hotel is clean and comfortable and the staff is courteous so i do want to say that first...BUT, the hotel's system of valet is a mess...we had to wait 30 mins. first day for our car. the next day i called […] ahead to avoid this. when we came down our car was out front but the driver had gone to get another car and instead of leaving key with the person at valet kiosk she took our key with us...we had to wait another 20 mins. i don't know where they park the cars, but they have to find a closer garage as the traffic in miami is often a mess and this, i believe was cause of delays. in addition the elevators went out twice during our 3 day stay...we had to walk up 11 flights of stairs TWICE during our stay. maybe this was just an isolated incident, but overall the management of the hotel seems to be a bit of a mess. a bag was also stolen from the hallway though this can't really be blamed on the hotel, i suppose, but still disappointing that no one turned it in to lost and found. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Extraordinary Front Desk Servic"
I had an embarrassing sequence of events that resulted in me arriving at this hotel without a valid reservation. Stanley, the front desk clerk, in an act of heroic proportions, found me a beautiful room with a grand view for a period that was to my perception fully booked. If for no other reason than Stanley's extraordinary efforts to make up for my […] mistake, I would come here again. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Great location. Fun surroundings"
This hotel is great, the only issue I had with it is the elevators. It's very old and small. We had to wait for longer than normal to get anywhere.Geverifieerde Hotels.com gastenbeoordeling
"Scenic Location with Plenty of Quality Surrounding"
After pulling up to the hotel for one night before our Cruise to the Caribbean, we checked in to the hotel. Service was extremely friendly and relaxing. Got checked into the room, ocean view on a mid level floor. Enjoyed the close walk to Bayside, and short drive to South Beach. The stay was amazing with a fireworks show over the port and being able […] to see our cruise ship we would board the next morning. The only major complaint I had was that the morning of checkout, we had an additional bill of $200. Once we got downstairs, I explained everything was paid for in advance, and they said it was a mistake. I checked out, went on our cruise for the week, and upon return home, noticed that $200 was actually posted to my account. I called the hotel without resolve, and was very disappointed in just that one thing. Everything was great except for the lack of honesty and communication with that miscellaneous charge, which I was only in town for 12 hours. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Close to American Airlines arena"
Everything was great. Only small draw back is this was easily the smallest bathroom we've found since a river cruise on an older ship.Geverifieerde Hotels.com gastenbeoordeling
The room was very, very small. The concierge could not tell me how to get to the hotel where I had my meetings-they told me to pay $10 for a cab and I later found out I could have taken the people mover for free. The bathroom was not clean-there was hair in the shower and toothpaste on the vanity from the previous stay. The air conditioner was very […] loud and woke me up every time it jump started on at night. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Excellent location"
The room was spotless and right across the street from great shops and restaurants. There was a drugstore just across the street for purchasing "forgotten items". My only "complaint" was that there was not a hair dryer in the room, otherwise, two thumbs up!Geverifieerde Hotels.com gastenbeoordeling
"Not Recommended"
Disgusting for the price they charged. Never going to go back to this property again in future.Geverifieerde Hotels.com gastenbeoordeling
"excellent location"
exceptional service, great location and amazing staff! definitely coming back.Geverifieerde Hotels.com gastenbeoordeling
"Modern, european style"
Small room, but nice quality and clean. The bar in the hotel serves many micro-brewery beers on tap. Easy to get to anywhere downtown using the free metromover (station is 3 blocks away).Geverifieerde Hotels.com gastenbeoordeling
"Not what your expecting"
I travel a lot and say in a lot of hotels… it takes a lot for me to leave a review. This is not I repeat not a 3 star hotel and not worth the money. Everything looks new in modern but it's really just painted white. The rooms are the size of a postage stamp and the bathrooms are smaller than that. All the rooms are very loud and the HVAC equipment loud […] to the point of disrupting sleep. Transferred rooms and this is the same in all rooms. If you need to sleep or want to be able to move around in your room this is not the hotel for you. you can find better option just about anywhere in this area. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Beautiful and nice,"
Ambiance was everything,Geverifieerde Hotels.com gastenbeoordeling
"Good price. Close to port"
Hotel was close to port and not too expensive. However, only two elevators for the entire hotel. Waiting on 7th floor for 30 min after 10 elevators came and went completely full at check out time was ridiculous. Finally walked down the stairs with all of our luggage. Room was ok and looks pretty but the hot water took 5 min to get warm. Room has been […] remodeled but still has some repair issues (sloped floor, chipped paint, only one small window). No hair dryer in room. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Nice place but not worth the headache"
We were saying at the B2 for the Ironman 70.3 as was everyone else staying there at that time. The elevators were very small to have to load bikes into. The staff were very rude to us when checking in. They would not allow us to check in a minute early and would not check our luggage including our bikes, so we had to drive around for an hour. When we […] came back at the check-in time (or 5 minutes before), we were told the room was still not ready. We had to wait in the lobby for about another 30 minutes with our luggage and bike, since there is no parking except valet. A couple of days after check-out, I noticed my credit card had been charged almost an extra $300. When I called, they said they had made a mistake and charged me instead of expedia. (Note: This was not even the amount that I paid for the hotel.) I was informed that it would be taken off my card in a couple of days! I will never stay at this hotel again. It is a nice, chic hotel but not worth the hassle, especially along with the stress of a race the next morning. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Nice hotel in downtown"
We stayed here the night before our cruise. It's only a $24 cab ride from MIA and there is a $6 shuttle to the airport. Very easy to get around. One note. The rooms are small so 4 people in one room was a little tight. That was fine with us as we were only there one night. I wouldn't suggest it for longer stays with more than 2 people.Geverifieerde Hotels.com gastenbeoordeling
Overall we enjoyed the hotel. The staff was friendly, however the efficiency of check in, check out and storage of luggage was not very efficient. Also the elevators were a bit of a disappointment. There are only 2 elevators in the hotel, so at times you would wait 5 - 10 minutes to get on an elevator.Geverifieerde Hotels.com gastenbeoordeling
"Great Hotel, with some bad details"
The Hotel is very well located, comfortable and clean. The negative points are: 1) elevator is always busy. Only 2 elevators for the entire tower. waiting time from 5 to 10 minutes to go up to your room. 2) Front desk personal are not that friendly, could be better. 3) Valet Parking: employees are very cool, friendly, but the waiting time varies from […] 10 to 20 minutes to receive your car. In the overall taring I give 4 from 5, in the end I recommend to stay there. Meer infoGeverifieerde Hotels.com gastenbeoordeling
Nice hotel, but very small bathrooms and only 2 elevators for 18 floors.Geverifieerde Hotels.com gastenbeoordeling
"Worst valet parking in town"
We use the Valet Parking Services from the hotel, and Every time we request for our car we need to wait for more than 35 minutes. Also If you came late after midnight be prepare to sit & wait for somebody to came and take you car. Also be careful with the check out, they change the rate in two of our group rooms without telling us!Geverifieerde Hotels.com gastenbeoordeling
"Small rooms"
This hotel is in a great location and has been completely renovated. The room was quite small though along with the bathroom. There is also only 2 small elevators so you have to wait a bit. Overall the staff were nice and friendly.Geverifieerde Hotels.com gastenbeoordeling
"great downtown hotel, close to Bayside Marketplace"
Newly renovated hotel close to Bayside Marketplace (5 min. walk). Super comfy beds. Didn't feel too comfortable steping in shower barefeet so I wore flip flops. Staff was very nice at front desk.Geverifieerde Hotels.com gastenbeoordeling
"Park and walk"
I loved the hotel, the staff and the quality of all, the exception is the noise, paper thin walls, hear your neighbors televisions, the street traffic, the dumpster being dumped.Geverifieerde Hotels.com gastenbeoordeling
"attending Triathalon"
Very satisfied - room quite small but very clean. No coffee machine or refrigerator. great location for our Triathalon event. Great staff.Geverifieerde Hotels.com gastenbeoordeling
"Form before Function"
B2 was in a great location and was obviously recently refinished. Unfortunately, there were many problems. The biggest was the Air Conditioner in our room, mounted in the ceiling, was incredibly loud. It woke me up several times during the night, which is something I've never had happen before. The other issue was that I had paid for a "bay view" room, […] which was only on the third floor and thus had no view of anything but the street. Definitely not worth the upgrade price. The elevators were incredibly slow, so being on the third floor turned out to be a good thing as we often used the stairs. The shower had no door or curtain, allowing water to splash all over the bathroom. There was also no vent fan, so it was quite steamy afterwards as well. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Good price nice location"
Location is right on the waterfront where there are shops and restaurants,and we chose the bay view room. It was decent size, tiny bathroom (like a cruise ship with a tub). Staff was great. Valet parking probably about right for Miami. NOTE: The entrance is NOT on Biscayne. You must enter from NW 2nd St.. Hoel restaurant serves a nice breakfast Z(buffet […] or from menu) Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Good location, small room but clean hotel"
No complaints! Good location in downtown Miami. Staff was friendly and pleasant. Rooms and bathrooms are small but functional. Will consider staying again. Valet parking is $30/night. Ouch, but you can find cheaper parking at nearby garages if you are so inclined.Geverifieerde Hotels.com gastenbeoordeling
"Excellent service"
I stayed for 5 nights and the service was excellent with a comfortable room and very clean. The guy in the front desk (Byron) treated us with much courtesy. Definitely I'll stay there next year. Thank you B2!Geverifieerde Hotels.com gastenbeoordeling
For the positives, the room was very clean, and the decor was modern and updated, the location was also very good and the receptionists were really nice and helpful. For the negatives, I felt like I paid too much to not have a free breakfast. It also took the valet 25 minutes to get me my car and when they did, they broke my keychain ! At first part […] of my keys were missing and they said "well this is how you have it to us" which was a lie. I asked them to look again and sure enough they found the broken piece of my keys which had my house and work keys on it. The valet employees also weren't very nice at all. They seemed irritated and I couldn't believe they lied to me to try to dismiss my missing keys. In the midst of taking care of me, I heard another man yelling because he was so upset, saying that the car they brought up wasn't his. The valet needs some improvement for sure. Meer infoGeverifieerde Hotels.com gastenbeoordeling
Once i got there ,a concert was just ending so it was pretty loud but overall it was excellent ,looking to return in march for a longer stayGeverifieerde Hotels.com gastenbeoordeling
I loved the style of the hotel and considering it was the same price as many of the average hotels in the area it was a lovely treat. The bed was luxurious, the shower was relaxing, everything in the room was styled very nicely. On top of that everything was extremely clean and well cared for. There was nothing I would change about my overnight sta […] y. Meer infoGeverifieerde Hotels.com gastenbeoordeling
Would not be staying there againGeverifieerde Hotels.com gastenbeoordeling
"Very bad night's sleep"
The hotel hasn't invested in soft-close doors, so room doors and even wardrobe doors slam shut very loudly. On my first night there there were lots of guests who had all been to a huge festival over the road - not in itself the hotel's fault, but they all came back between 2am and 5am, so there was a constant procession of slammed doors, and I barely […] slept a wink. Add to that the fact that my room wasn't cleaned for my entire stay (3 nights) and it wasn't great, really. Location is OK, not too bad for downtown. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Close to Miami Port"
The B2 was very modern and clean. The room was an okay size for a one night stay. The bathroom was extremely small. Smallest I've ever seen in a hotel. But again, very clean. The staff was exceptionally nice and overly helpful. Would definitely stay again if we were sailing out of the Miami Port.Geverifieerde Hotels.com gastenbeoordeling
"Great Location!"
I enjoyed my stay. It was very busy because of festivals and concerts happening the weekend of. They come up to your room if you need anything. This is not a hotel that you come to to relax. It's more perfect for the location and being able to walk everywhere u need to go. i will stay here again for sure. Room was clean. Service was great. They bring […] toothbrush, toothpaste, etc up to your room as long as you call them. The only really negative thing I'd say is you have to pay for valet if you stay here. every night its a fee. Meer infoGeverifieerde Hotels.com gastenbeoordeling
The rooms, as you may have seen stated, are not large, BUT they are spotless, new, and have a great view of the harbor. The staff was quick and efficient. It is a great location with many restaurants within walking distance, and shopping galore on Flagler Street and Bayside Marketplace. Taxi's at the door and buses across street to South Beach. All […] in all a good choice at a great price. Meer infoGeverifieerde Hotels.com gastenbeoordeling
"Excellent Hotel right in fron of Bayside"
If you are looking for a hotel near to Bayside and Downtown this one is excellent. Cleanliness and confortable. The rooms are quiet small but if you are traveling for business or a place near to commercial bank area is good enough. The only problem that I found is the parking area. The Hotel charge you $30 for valet parking and if you are going around […] you can find municipal parking for $20 overnight. The food and the bar are excellent and friendly personal. Meer infoGeverifieerde Hotels.com gastenbeoordeling
the Air Conditioner is too loud, got no Sleep, never again....Geverifieerde Hotels.com gastenbeoordeling
"Match box"
Too smallGeverifieerde Hotels.com gastenbeoordeling
"Extremely noisey airconditioning"
When we asked staff about local attractions they were unable to help us! After complaining about noisy room airconditioning we were offered a tiny room with no other options. Used earplugs to block out the noise to enable sleeping. RegardsGeverifieerde Hotels.com gastenbeoordeling
"Nice hotel in downtown Miami"
This is a nice hotel completely renovated, the staff is really nice, the only issues are: the parking, it is a little expensive 31 dollars per night of you can leave your car about a block away in a parking lot. the room size, it is a small room with a small bathroom. Also the zone where it is located is really nice during the morning hours but in the […] night it doesn't seem like the safest place. Meer infoGeverifieerde Expedia gastenbeoordeling
"Good location. Good service."
We liked the hotel. The first night our room did not match the description in the ad. We asked for a room change and we were accommodated.Geverifieerde Hotels.com gastenbeoordeling
"Close to American Airlines."
It was a nice clean house but didn't describe actual view of room.Geverifieerde Hotels.com gastenbeoordeling
Completely satisfied with location and service.Geverifieerde Hotels.com gastenbeoordeling
"Very functional hotel, excellent service"
It's very practical, small rooms, but has everything you need and very new. Hotel staff very friendly, but parking around that area is obviously expensive. Gym pretty small, but works. If you need downtown, very recommendable!Geverifieerde Expedia gastenbeoordeling
Beoordelingen op deze site zijn de persoonlijke meningen van klanten en leveranciers, en niet die van Hotels.com. Noch Hotels.com noch de partijen die deze beoordelingen plaatsen, kunnen aansprakelijk worden gesteld voor schade van welke soort ook die voortvloeit uit het gebruik van deze beoordelingen


text:
New Single "Heart Attack" Available Now!
I agree, Takin back my love and addicted also, but i really love them all :)
I really like: "Taking Back My Love", "I Like How It Feels", "Do You Know", "Somebody's Me", "Heartbeat"... I think these are my favorite!
sad eyes :)) Hero
All videos, but one is the most and that's Donde Estan Corazon. :)
gosh i love them all! but yeah i'd have to say takin back my love and i like it and i like how it feels...that one gives me shivers up my back!
me too...blush..Lol..Sarah
I really love the concert Takin Back my love vids..when he is playing around with Laura..
hey Sarah! I totally agree with you about the TBML videos with Laura. they look like they're having so much fun.
© 2013 Created by Enrique Iglesias.


text:
"Where's My CAKE?!" COMICS! Sometimes They Are A Bit Like Films (CREEPSHOW)!
Posted by: John Kane on June 17, 2012
Categories: Reviews
There came a day pretty much like any other day, except sales of Godawful Tony Parsons books went up. The Day of The Father! I hope you got yours a cake, kiddies! We Dads can hold a grudge for a long, long time! Heh. Heh. Heh.


text:
A Fun.-filled Grammys red carpet
It wouldn't be surprising if you assumed the monster success behind Fun.'s "We Are Young" with Janelle Monáe was the calculated work of a studio, but that's not the case.
"It wasn't about a record label putting two hot artists together," Fun. member Andrew Dost told CNN on the red carpet. "Janelle's an artist and just wanted to be a part of the song."
Indeed, Monáe told us on Sunday that she "didn't know it was going to be such a big song, I just knew I loved it."
To Monáe, "We Are Young" is "cross-generational," but for Dost, Nate Ruess and Jack Antonoff the song "was a little more negative, and suddenly it just had this positive anthemic effect on people."
The band, which is one of the lead nominees at the 55th ceremony, is made up of "great guys," Monáe said. "[They] deserve every accoalade."
Copyright 2013 by CNN NewSource. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


text:
Jareth Li
Third season: Assistant lighting designer of Tommy and Othello. Stratford: Assistant lighting designer of You're a Good Man, Charlie Brown, The Little Years, Shakespeare's Will, Hosanna. Elsewhere: Lighting designer of The House of Bernarda Alba (Randolph Academy), Ice Cave Aurora Borealis (Harbourfront Centre), The Long Red Road (Column 13), The Boat People (Red Pocket Collective), Table Talk (Theatre@York). Assistant lighting designer of Tristan und Isolde, Il Trovatore, L'Amour de Loin, The Magic Flute, Idomeneo (Canadian Opera Company); The Small Room at the Top of the Stairs, The Children's Republic (Tarragon Theatre). Tour lighting director for Just for Laughs (Canadian Tour), Gita Govinda (Menaka Thakkar Dance Company). Training: York University – Theatre Design and Technical Production. Awards: Wally Russell Internship, 2010, at the Canadian Opera Company.


text:
By Rabbi Avie Gold (Author) Rabbi Meir Zlotowitz Rabbi Nosson Scherman (Joint Author) List Price: $54.99 Online Discount: 10% You Pay Only: $49.49Catalog #: MSAL-A ISBN-10: 0899066925 ISBN-13: 9780899066929Binding: Leather Alligator / Pages: 1305Dimensions: 6 x 9 inches / Weight: 2.20 LBSPublished: by ArtScroll Mesorah PublicationsIn Stock?: YES
A Prayer book for our times, it speaks to today's Jew, relating the thoughts and words of our heritage to the mind and heart of modern, sophisticated Jews.
Browse Related Books:Books > Gift Suggestions > Deluxe Leather Editions > Machzorim for Holidays & Festivals > Machzor: Sukkos/Simchat Torah Holiday Prayer BooksBooks > Machzorim for Holidays & Festivals > Machzorim - Festival Prayer Books - AllBooks > Machzorim for Holidays & Festivals
Other Selected Titles by Rabbi Avie Gold: Family Haggadah: Enlarged EditionHaggadah: Illustrated Youth EditionHoshanosMachzor Pesach - Pocket Sefard - White LeatherPirkei Avos - Illustrated Youth Edition More... Click here for full list Other Selected Titles by Rabbi Meir Zlotowitz: Ashkenaz - Yerushalayim 2-Tone Leather Schottenstein Ed. Interlinear 5 Vol SetChanukah: Its History, Observance, And SignificanceMachzor Succos Ashkenaz - White LeatherSiddur Hebrew/English: Complete Pocket Size - Ashkenaz (Paperback)Yonah / Jonah More... Click here for full list Other Selected Titles by Rabbi Nosson Scherman: Machzor Succos Pocket Size Sefard - Maroon LeatherMachzor Yom Kippur Full Size Ashkenaz - White LeatherPerek Shirah - The Song of the Universe - Pocket SizeShmuel I / I SamuelStone Edition Chumash Full Size Maroon Leather Edition More... Click here for full list


text:
Advanced Search
Several airport weather reporting stations have switched over to new NAV Canada sensors and reporting tools. Please click here and expand the message for the list of new NAV Canada stations with the latest data:
The Notice Inventory contains a record of all past and current Notices.
We'd like to hear from you! Please click Contact Us to share your comments and suggestions.
To determine data availability for a custom location and date, please complete and submit one of the following searches:
Search by Province
Search by Station Name
Search by Proximity
- Date modified:


text:
Need it by Christmas Eve?
Men's adidas Running Shoes
adizero Adios Boost Shoes
Hero Ink/Metalsilver (G95112)
Size Chart
+ Save To Wishlist
Rated 5 out of 5Â by 19
Rated 5 out of 5Â by MarcTut1 Best Running Shoe Ever!!!
When the Boosts came out I fell in love with the midsole and decided that this is going to be my new distance training shoe. After running through the hot summer months, the techfit upper did not provide the breathability I wanted for the heat and was used to in a fast shoe, so I had some sweat accumulation. The Adios Boost model fixed this concern and is very light yet maintains the great padding and rebound of the Boost midsole. If I were to design a perfect running shoe, this would be it. This is the first shoe I have owned that is so light that you don't even feel it, yet is so cushioned that your feet never hurt. I'll probably buy these for as long as Adidas makes them!
October 10, 2013
Rated 5 out of 5Â by Opusrunner Wow!
I've lusted after this shoe since seeing it for the first time at the Boston Marathon Expo this year. It does not disappoint! My previous go to racing flat was the DS9. I find the toe box to be roomy. Ride is very neutral. Unlike other reviewers I find the sole very flat and I'm very appreciative of the sandpaper like gripping surface which proved very nonslip during a recent wet surface race. At high speed the sole gives a satisfying pop on impact and lift off. The only thing I would improve is duplicating the sock upper of the Boost Adistar Shoe. When walking I was concerned the nylon would give me a blister during a race, but that proved not to be a problem and my racing has been blister free.
October 7, 2013
Rated 5 out of 5Â by Elijah Teixeira Adidas Is #1
So, hear it is. I can write about how these are the best shoes in the entire world. (Because they are) Instead I'm going to describe how as a runner your shoes mean everything.
I am a huge Adidas fan, and supporter! I wear nothing but Adidas when it comes to physical fitness. I have Adidas spikes, shoes, apparel, and compressions.
Now for the good stuff! I am a 17 year old high school senior trying to seek an appointment to The (U)nited (S)tates (M)ilitary (A)cademy at West Point, NY. With that being said you have to very physically fit. USMA requires to take a (C)andidate (F)itness (A)ssement. I'm a pretty good runner and did really well, and passed my CFA. Once passed you are authorize one improvement test. This meant I had to take it up a level. After a year and several months. I finally confidence my mother to buy me the Adidas Boost! After the spending hours in Fleet Feet, doing several test runs, and while trying on many pairs of shoes I finally made my mind on the Adidas Adios Boost. I went for a run that night and it felt beyond amazing!
Just today (11/14/13) I had to take a physical fitness test in JROTC. With the power of the boost I ran 10x harder and PR by 25sec and received the National Physical Fitness award. I HIGHLY recommend these shoes. They feel amazing, with propulsion every time your foot strikes the ground. The advanced technology of the fit foam truly provides a different feel to your running. It won 1st, 2nd, and 3rd in the NY marathon. That should tell you just how great they are.
Adidas will always be my favorite shoe brand and I hope everyone can benefit from the wonder experience I have with my Adidas products everyday!
November 14, 2013
Rated 5 out of 5Â by Tommy Boy Pretty much Fantastic
These shoes are the shoes to get things done in. They are extremely light and the boost foam makes them even that much better. I love it when I start running because I quickly forget that I have any shoes on at all and I feel like I can go forever. Even when you spend a long day in these shoes at a meet your feet never really get tired. The only hiccup in the design of the shoe though is the middle strip of rubber on the sole. The shoe bows slightly there and so it reaches the ground first. While running this is irrelevant and the feeling of something in the middle of your foot quickly goes away, but while standing around it is constantly present and I feel as if the bottom of my feet are slightly bruised in the middle.
October 5, 2013
Rated 5 out of 5Â by GACE Great start so far
I have worn the Adios Boost for ~25 miles. I intend on utilizing these shoes for marathons and select tempo/long runs. The feel of the shoe right out of the box was great. After 3 miles I was able to complete a 18-mile run without any issues (e.g., hot spots, blisters). I purchased the shoe 1/2 size bigger then I normally wear and the shoe fits perfectly. My only concern at this point is the durability of the black rubber sole. I have already noticed significant wear.
October 18, 2013
Rated 5 out of 5Â by Fabrice Must have
Very different feel from the adios, second time I wear them went for a 50 miles run in SoCal trail and love the shoes. Good support and cushioning. This shoe is a keeper for long distance running.
October 16, 2013
Rated 5 out of 5Â by momoney 44 Rides Well
With adios 2 and boost being my favorite running shoes, I had to get these shoes. on the look these are great. Can't wait for new colors. On performance I only got a couple runs. so far the ride is smooth, light, and comfortable! but if you still like the racer feel, the adios 2 are better. I'll have to see how they do in a race. Adidas never lets me down.
October 3, 2013
Rated 5 out of 5Â by Egil Fantastic!!!
I was extremely satisfied with my previous Asics Hyperspeed 4 shoes. When Asics stopped production of these shoes I had to look for another option. After trying out 7 different alternatives I finally found the shoe which is just amazing. During my first 8 mile run I just knew that this would be my future shoe. I fully recommend this shoe to everybody who enjoy running in a light shoe.
October 23, 2013
Rated 5 out of 5Â by Joyse Just WOW!
I was sold on them the second I put my foot in them! Just wow! Amazing breath-ability. Amazing support. They feel like they were made for my foot!
October 10, 2013
Rated 5 out of 5Â by AC Almost the Best Shoes Ever
These shoes are second only to the Adizero Adios Shoes (Non Boost).
November 25, 2013
Rated 5 out of 5Â by 19
Rated 5 out of 5Â by Filipe Really a must
I've already tried a Boost model before but this one as all I need from a fast shoe, light but still protects me from injuries. All I expect to obtain my PR's. Thanks Adidas team.
Only an advice, buy a size greater than usual.
December 17, 2013
Rated 5 out of 5Â by yeags Fast!!
I first saw these at the Boston Marathon Expo. I tried the Original Boost and liked it as a training shoe. I used the original Adios as a racing shoe. Combining the two made this shoe on the top of my list. Running in it did not disappoint. The upper is roomier and more breathable than the boost. There is less cushion than the boost so it feels a touch more conventional. I've raced in them twice and had 2 PR's. Love it!!
October 28, 2013
Rated 5 out of 5Â by Sawdust Great shoe!
Fantastic shoe. Fits true to size and provides superior cushioning. This shoe keeps the guidance Adios shoes are famous for with additional cushioning to make tempo runs and long runs doable. Still very light. Bravo!
October 21, 2013
Rated 5 out of 5Â by SONG26.2 Adios Boost are GREAT
GREAT Shoe, light weight, comfortable, great cushion from the the BOOST, good natural feel, good traction on the road in the cold, looks great as well, much better than the Energy Boost for weight and feel, so far its my go to shoe for 9 miles per day, along with Newton Distance shoe.
November 30, 2013
Rated 5 out of 5Â by 1stcav Adios Boost, love these shoes
for me, true to size, light comfortable and I'm gonna get another pair, I run (very slow as I'm over 70) 25-30 miles a week, due to my age I need good support, it is great to find it in such a light shoe
November 14, 2013
Rated 5 out of 5Â by gvlakerkiid GREAT SHOE
Best shoe that I have ever had, i thought that the energy return wouldn't be as good as the person at adidas told me, it was better.
November 16, 2013
Rated 5 out of 5Â by Youlikeapples Back to back marathons
I ran back to back marathons in these and they are awesome. Very light yet responsive.
November 12, 2013
Rated 5 out of 5Â by LeoB Awesome shoes!!! Light, comfortable, & great marathon shoe.
October 23, 2013


text:
- Alcoholic liver disease (1)
- Digestive system (1)
- Endoscopy (1)
- Fibrotest (1)
- Hepatitis (1)
- Hepatotoxicity (1)
- Interleukin-22 (1)
- Intestinal neoplasms (1)
- Letalität auf der Warteliste und Transplantation bei Leberallokation nach MELD Score in Deutschland - erste prospektive Ergebnisse bei 100 Patienten (2008)
- Meeting Abstract : Deutsche Gesellschaft für Chirurgie. 125. Kongress der Deutschen Gesellschaft für Chirurgie. Berlin, 22.-25.04.2008 Einleitung: Am 16.12.06 wurde im Eurotransplant-Gebiet der MELD-Score (MELD) als Allokationsbasis zur Lebertransplantation (OLT) eingeführt. Ziel ist eine Reduktion der Sterblichkeit auf der Warteliste. Material und Methoden: 100 Patienten wurden in die prospektive Analyse der MELD-Allokation vom 16.12.06 bis 15.09.07 einbezogen. Ergebnisse: Aktuell warten 68 Pat., 28 Pat. wurden transplantiert, 4 Pat. sind auf der Warteliste (WL) verstorben (4%). Der mittlere MELD auf der WL beträgt 17,2 +/- 5,2 (7-28). Bei 12 Pat. liegt eine Standard-exception (SE) (n=10 HCC, n=2 metabolische Erkrankung) mit einem Match-MELD von 25,6 +/-2,06 vor (24-28). Die Todesursachen der vier auf der WL verstorbenen Pat. waren eine akute Varizenblutung (MELD 9), zwei kardiale Versagen (MELD 13, 18) und eine MRSA-Sepsis (MELD 29, NT-Status). Die 28 transplantierten Pat. hatte zum Zeitpunkt der Transplantation einen mittleren MELD von 27,66 +/- 5,1 Punkten (21 bis 40). 20 Pat. wurden aufgrund des Labor-MELD (28,4 +/- 5,3, 24-40) transplantiert, wobei 7 Pat. einen MELD über 30 aufwiesen. Die Wartezeit lag bei 11,55 +/- 5,3 Tagen. 8 Pat. erhielten bei SE bei HCC (MELD 24 +/- 0, 24) ein Organ nach einer Wartezeit von 320 +/- 9,7 Tagen. Aktuell leben 23 der 28 transplantierten Pat. Bei zwei verstorbenen Pat. war die Todesursache ein kardiales Versagen, bei zwei Patienten eine primäre Non-Funktion sowie ein septisches Multiorganversagen. Schlussfolgerung: Während der ersten Monate der MELD Allokation lag die Letalität auf der WL in unserem Zentrum bei 4%. Patienten mit einem mittleren MELD über 27 erhielten Organangebote und konnten nach kurzer Wartezeit transplantiert werden.
- Comparison of ELF, FibroTest and FibroScan for the non-invasive assessment of liver fibrosis (2010)
- Background: FibroTest (FT) is the most frequently used serum fibrosis marker and consists of an algorithm of five fibrosis markers (alfa2-macroglobulin, apolipoproteinA1, haptoglobin, GGT, bilirubin). The Enhanced Liver Fibrosis (ELF) test consists of an algorithm of three fibrosis markers (hyaluronic acid, amino-terminal propeptide-of-type-III-collagen, tissue-inhibitor of matrix-metaloproteinase-1). While a systematic review has shown comparable results for both individual markers, there has been no direct comparison of both markers. Methods: In the present study, the ELF-test was analyzed retrospectively in patients with chronic liver disease, who received a liver biopsy, transient elastography (TE) and the FibroTest using histology as the reference method. Histology was classified according to METAVIR and the Ludwig's classification (F0-F4) for patients with chronic hepatitis C and B virus (HCV, HBV) infection and primary biliary cirrhosis (PBC), respectively. Results: Seventy-four patients were analysed: 36 with HCV, 10 with HBV, and 28 with PBC. The accuracy (AUROC) for the diagnosis of significant fibrosis (F[greater than or equal to]2) for ELF and FibroTest was 0.78 (95%CI:0.67-0.89) and 0.69 (95%-CI:0.57-0.82), respectively (difference not statistically significant, n.s.). The AUROC for the diagnosis of liver cirrhosis was 0.92 (95%CI:0.83-1,00), and 0.91 (95%CI:0.83-0.99), respectively (n.s.). For 66 patients with reliable TE measurements the AUROC for the diagnosis of significant fibrosis (cirrhosis) for TE, ELF and FT were 0.80 (0.94), 0.76 (0.92), and 0.67 (0.91), respectively (n.s.). Conclusion: FibroTest and ELF can be performed with comparable diagnostic accuracy for the non-invasive staging of liver fibrosis. Serum tests are informative in a higher proportion of patients than transient elastography.
- Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma (2011)
- Background: MicroRNA-21 (miR-21) is up-regulated in tumor tissue of patients with malignant diseases, including hepatocellular carcinoma (HCC). Elevated concentrations of miR-21 have also been found in sera or plasma from patients with malignancies, rendering it an interesting candidate as serum/plasma marker for malignancies. Here we correlated serum miR-21 levels with clinical parameters in patients with different stages of chronic hepatitis C virus infection (CHC) and CHC-associated HCC. Methodology/Principal Findings: 62 CHC patients, 29 patients with CHC and HCC and 19 healthy controls were prospectively enrolled. RNA was extracted from the sera and miR-21 as well as miR-16 levels were analyzed by quantitative real-time PCR; miR-21 levels (normalized by miR-16) were correlated with standard liver parameters, histological grading and staging of CHC. The data show that serum levels of miR-21 were elevated in patients with CHC compared to healthy controls (P<0.001); there was no difference between serum miR-21 in patients with CHC and CHC-associated HCC. Serum miR-21 levels correlated with histological activity index (HAI) in the liver (r = −0.494, P = 0.00002), alanine aminotransferase (ALT) (r = −0.309, P = 0.007), aspartate aminotransferase (r = −0.495, P = 0.000007), bilirubin (r = −0.362, P = 0.002), international normalized ratio (r = −0.338, P = 0.034) and γ-glutamyltransferase (r = −0.244, P = 0.034). Multivariate analysis revealed that ALT and miR-21 serum levels were independently associated with HAI. At a cut-off dCT of 1.96, miR-21 discriminated between minimal and mild-severe necroinflammation (AUC = 0.758) with a sensitivity of 53.3% and a specificity of 95.2%. Conclusions/Significance: The serum miR-21 level is a marker for necroinflammatory activity, but does not differ between patients with HCV and HCV-induced HCC.
- Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life : an international, multicenter, randomized, controlled study (2012)
- Background: Hepatitis C decreases health related quality of life (HRQL) which is further diminished by antiviral therapy. HRQL improves after successful treatment. This trial explores the course of and factors associated with HRQL in patients given individualized or standard treatment based on early treatment response (Ditto-study). Methods: The Short Form (SF)-36 Health Survey was administered at baseline (n = 192) and 24 weeks after the end of therapy (n = 128). Results: At baseline HRQL was influenced by age, participating center, severity of liver disease and income. Exploring the course of HRQL (scores at follow up minus baseline), only the dimension general health increased. In this dimension patients with a relapse or sustained response differed from non-responders. Men and women differed in the dimension bodily pain. Treatment schedule did not influence the course of HRQL. Conclusions: Main determinants of HRQL were severity of liver disease, age, gender, participating center and response to treatment. Our results do not exclude a more profound negative impact of individualized treatment compared to standard, possibly caused by higher doses and extended treatment duration in the individualized group. Antiviral therapy might have a more intense and more prolonged negative impact on females.
- Assessment of liver fibrosis and associated risk factors in HIV-infected individuals using transient elastography and serum biomarkers (2012)
- Background: Liver fibrosis in human immunodeficiency virus (HIV)-infected individuals is mostly attributable to co-infection with hepatitis B or C. The impact of other risk factors, including prolonged exposure to combined antiretroviral therapy (cART) is poorly understood. Our aim was to determine the prevalence of liver fibrosis and associated risk factors in HIV-infected individuals based on non-invasive fibrosis assessment using transient elastography (TE) and serum biomarkers (Fibrotest [FT]). Methods: In 202 consecutive HIV-infected individuals (159 men; mean age 47 ± 9 years; 35 with hepatitis-C-virus [HCV] co-infection), TE and FT were performed. Repeat TE examinations were conducted 1 and 2 years after study inclusion. Results: Significant liver fibrosis was present in 16% and 29% of patients, respectively, when assessed by TE (≥ 7.1 kPa) and FT (> 0.48). A combination of TE and FT predicted significant fibrosis in 8% of all patients (31% in HIV/HCV co-infected and 3% in HIV mono-infected individuals). Chronic ALT, AST and γ-GT elevation was present in 29%, 20% and 51% of all cART-exposed patients and in 19%, 8% and 45.5% of HIV mono-infected individuals. Overall, factors independently associated with significant fibrosis as assessed by TE (OR, 95% CI) were co-infection with HCV (7.29, 1.95-27.34), chronic AST (6.58, 1.30-33.25) and γ-GT (5.17, 1.56-17.08) elevation and time on dideoxynucleoside therapy (1.01, 1.00-1.02). In 68 HIV mono-infected individuals who had repeat TE examinations, TE values did not differ significantly during a median follow-up time of 24 months (median intra-patient changes at last TE examination relative to baseline: -0.2 kPa, p = 0.20). Conclusions: Chronic elevation of liver enzymes was observed in up to 45.5% of HIV mono-infected patients on cART. However, only a small subset had significant fibrosis as predicted by TE and FT. There was no evidence for fibrosis progression during follow-up TE examinations.
- A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers (2012)
- Background and Aims: Chronic infection with the hepatitis B virus (HBV) is a major health issue worldwide. Recently, single nucleotide polymorphisms (SNPs) within the human leukocyte antigen (HLA)-DP locus were identified to be associated with HBV infection in Asian populations. Most significant associations were observed for the A alleles of HLA-DPA1 rs3077 and HLA-DPB1 rs9277535, which conferred a decreased risk for HBV infection. We assessed the implications of these variants for HBV infection in Caucasians. Methods: Two HLA-DP gene variants (rs3077 and rs9277535) were analyzed for associations with persistent HBV infection and with different clinical outcomes, i.e., inactive HBsAg carrier status versus progressive chronic HBV (CHB) infection in Caucasian patients (n = 201) and HBsAg negative controls (n = 235). Results: The HLA-DPA1 rs3077 C allele was significantly associated with HBV infection (odds ratio, OR = 5.1, 95% confidence interval, CI: 1.9–13.7; p = 0.00093). However, no significant association was seen for rs3077 with progressive CHB infection versus inactive HBsAg carrier status (OR = 2.7, 95% CI: 0.6–11.1; p = 0.31). In contrast, HLA-DPB1 rs9277535 was not associated with HBV infection in Caucasians (OR = 0.8, 95% CI: 0.4–1.9; p = 1). Conclusions: A highly significant association of HLA-DPA1 rs3077 with HBV infection was observed in Caucasians. However, as a differentiation between different clinical courses of HBV infection was not possible, knowledge of the HLA-DPA1 genotype cannot be translated into personalized anti-HBV therapy approaches.
- Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity (2012)
- Aim: Cellular CD81 is a well characterized hepatitis C virus (HCV) entry factor, while the relevance of soluble exosomal CD81 in HCV pathogenesis is poorly defined. We performed a case-control study to investigate whether soluble CD81 in the exosomal serum fraction is associated with HCV replication and inflammatory activity. Patients and Methods: Four cohorts were investigated, patients with chronic hepatitis C (n = 37), patients with chronic HCV infection and persistently normal ALT levels (n = 24), patients with long term sustained virologic response (SVR, n = 7), and healthy volunteers (n = 23). Concentration of soluble CD81 was assessed semi-quantitatively after differential centrifugation ranging from 200 g to 100,000 g in the fifth centrifugation fraction by immunoblotting and densitometry. Results: Soluble CD81 was increased in patients with chronic hepatitis C compared to healthy subjects (p = 0.03) and cured patients (p = 0.017). Patients with chronic HCV infection and persistently normal ALT levels and patients with long term SVR had similar soluble CD81 levels as healthy controls (p>0.2). Overall, soluble CD81 levels were associated with ALT levels (r = 0.334, p = 0.016) and severe liver fibrosis (p = 0.027). Conclusion: CD81 is increased in the exosomal serum fraction in patients with chronic hepatitis C and appears to be associated with inflammatory activity and severity of fibrosis.
- Hepatitis C viral evolution in genotype 1 treatment-naïve and treatment-experienced patients receiving telaprevir-based therapy in clinical trials (2012)
- Background: In patients with genotype 1 chronic hepatitis C infection, telaprevir (TVR) in combination with peginterferon and ribavirin (PR) significantly increased sustained virologic response (SVR) rates compared with PR alone. However, genotypic changes could be observed in TVR-treated patients who did not achieve an SVR. Methods: Population sequence analysis of the NS3•4A region was performed in patients who did not achieve SVR with TVR-based treatment. Results: Resistant variants were observed after treatment with a telaprevir-based regimen in 12% of treatment-naïve patients (ADVANCE; T12PR arm), 6% of prior relapsers, 24% of prior partial responders, and 51% of prior null responder patients (REALIZE, T12PR48 arms). NS3 protease variants V36M, R155K, and V36M+R155K emerged frequently in patients with genotype 1a and V36A, T54A, and A156S/T in patients with genotype 1b. Lower-level resistance to telaprevir was conferred by V36A/M, T54A/S, R155K/T, and A156S variants; and higher-level resistance to telaprevir was conferred by A156T and V36M+R155K variants. Virologic failure during telaprevir treatment was more common in patients with genotype 1a and in prior PR nonresponder patients and was associated with higher-level telaprevir-resistant variants. Relapse was usually associated with wild-type or lower-level resistant variants. After treatment, viral populations were wild-type with a median time of 10 months for genotype 1a and 3 weeks for genotype 1b patients. Conclusions: A consistent, subtype-dependent resistance profile was observed in patients who did not achieve an SVR with telaprevir-based treatment. The primary role of TVR is to inhibit wild-type virus and variants with lower-levels of resistance to telaprevir. The complementary role of PR is to clear any remaining telaprevir-resistant variants, especially higher-level telaprevir-resistant variants. Resistant variants are detectable in most patients who fail to achieve SVR, but their levels decline over time after treatment.
- C-terminal fluorescent labeling impairs functionality of DNA mismatch repair proteins (2012)
- The human DNA mismatch repair (MMR) process is crucial to maintain the integrity of the genome and requires many different proteins which interact perfectly and coordinated. Germline mutations in MMR genes are responsible for the development of the hereditary form of colorectal cancer called Lynch syndrome. Various mutations mainly in two MMR proteins, MLH1 and MSH2, have been identified so far, whereas 55% are detected within MLH1, the essential component of the heterodimer MutLα (MLH1 and PMS2). Most of those MLH1 variants are pathogenic but the relevance of missense mutations often remains unclear. Many different recombinant systems are applied to filter out disease-associated proteins whereby fluorescent tagged proteins are frequently used. However, dye labeling might have deleterious effects on MutLα's functionality. Therefore, we analyzed the consequences of N- and C-terminal fluorescent labeling on expression level, cellular localization and MMR activity of MutLα. Besides significant influence of GFP- or Red-fusion on protein expression we detected incorrect shuttling of single expressed C-terminal GFP-tagged PMS2 into the nucleus and found that C-terminal dye labeling impaired MMR function of MutLα. In contrast, N-terminal tagged MutLαs retained correct functionality and can be recommended both for the analysis of cellular localization and MMR efficiency.
- High prevalence of anti-HCV antibodies in two metropolitan emergency departments in Germany: a prospective screening analysis of 28,809 patients (2012)
- Background and Aims: The prevalence of hepatitis C virus (HCV) antibodies in Germany has been estimated to be in the range of 0.4–0.63%. Screening for HCV is recommended in patients with elevated ALT levels or significant risk factors for HCV transmission only. However, 15–30% of patients report no risk factors and ALT levels can be normal in up to 20–30% of patients with chronic HCV infection. The aim of this study was to assess the HCV seroprevalence in patients visiting two tertiary care emergency departments in Berlin and Frankfurt, respectively. Methods: Between May 2008 and March 2010, a total of 28,809 consecutive patients were screened for the presence of anti-HCV antibodies. Anti-HCV positive sera were subsequently tested for HCV-RNA. Results: The overall HCV seroprevalence was 2.6% (95% CI: 2.4–2.8; 2.4% in Berlin and 3.5% in Frankfurt). HCV-RNA was detectable in 68% of anti-HCV positive cases. Thus, the prevalence of chronic HCV infection in the overall study population was 1.6% (95% CI 1.5–1.8). The most commonly reported risk factor was former/current injection drug use (IDU; 31.2%) and those with IDU as the main risk factor were significantly younger than patients without IDU (p<0.001) and the male-to-female ratio was 72% (121 vs. 46 patients; p<0.001). Finally, 18.8% of contacted HCV-RNA positive patients had not been diagnosed previously. Conclusions: The HCV seroprevalence was more than four times higher compared to current estimates and almost one fifth of contacted HCV-RNA positive patients had not been diagnosed previously.


text:
List of High Schools:
Missing and Exploited Children
Jasper County - Missouri
Newton County - Missouri
Crawford County - Kansas
Visit NBCNews.com for breaking news, world news, and news about the economy
Paula Moore tells of the need for blood as Christmas nears and holiday travel increases.
Darth Vader and a Storm Trooper explain the toy drive.
Dr. Leavens explains the difference between dangerous substances that can poison your pet and others that might just give them tummy troubles.
Firefighter Shannon Branham explains the time frame for families to apply for help with Christmas gifts, and how viewers can pitch in.
Artist Linda Lindquist Baldwin preps for her annual celebration, where she'll autograph her original works for buyers.
Shelby Bates enumerates the savings that can be found daily.
Dr. Sue explains what each kind of flu vaccine does, and who should receive them.
Gary meets client Nicholas Willis, who shows off some of his riding accomplishments.
Devin Gorman previews the free calendar, which comes out later this week.
Gary talks with Shelly McColm and Vallerie Sweeton about how riding therapy helps their clients.
As temperatures continue to drop, it's important to remember our four legged friends.
For the month of November all senior dogs can be adopted for $15 at the Joplin Humane Society.
The Food and Drug Administration proposes preventive measures to protect all animal foods from food-borne illnesses.
Stephanie Lagow DeTar tells about a project that provides donors with a portrait of their pet in exchange for a donation of dog food or cash to a local animal shelter.
Dr. Ben Leavens has a few more suggestions in dealing with pet etiquette when you introduce your animal into a group setting. In this segment, it's socialization.
Dr. Ben Leavens discusses etiquette and precautions pet owner should take before introducing their animals into a group situation. In this segment, it's vaccinations.
Parr Hill Park in Joplin reopens to the public.
The veterinarian explains that "thermal gain" is as big a danger to dogs as sunburn, and not as easy to spot.
Workers at the Joplin Animal Adoption and Resource Center suggest bringing your animals indoors if they are scared of fireworks.
Dr. Sue gives tips on how to keep from being bitten by a dog, and what to do if it does happen.


text:
The mother accused of killing her 8-day-old baby has been indicted on first degree pre-meditated murder and aggravated child abuse charges, following a grand jury hearing May 3.
On April 16, Michelle Marie Vasquez, 34, of Midway, was arrested by Santa Rosa County Sheriff's deputies when she emerged from the woods near her parents' home on Congress Street, saying she killed her baby.
Vasquez was reported missing by her parents, with who she was living with at the time, on April 15. She had taken her infant, Madison Marie Florez, with her.
The following day, Vasquez's stepfather, flagged down deputies, claiming to have found his stepdaughter and grand-daughter in the woods.
In a report released by the Santa Rosa County Sheriff's Office, Vasquez left her parent's home because "she felt that she did not belong there." Vasquez told Deputy Scott Zohn that she wanted to live on the streets.
Zonh's report stated that Vasquez admitted holding the baby "really tight to comfort her." She also repeatedly stated "I killed my baby," and "I am a murderer," while Zohn was questioning her.
When Zohn asked Vasquez if she knew what would happen if she held a baby too tight, she said "die."
Vasquez, who is an unemployed single mother, also has a two year-old daughter.
By the time authorities found Vasquez, the baby appeared to have been dead "for some time." Deputies found her wrapped in a blanket, lying on the ground.
An investigation by the sheriff's office and the Office of the Medical Examiner revealed that Vasquez had smothered the child.
When asked if Vasquez had been suffering from postpartum depression, her mother said she seemed fine.
Vasquez was scheduled to be in court for an arraignment hearing Wednesday, May 12.


text:
Signature Collection
Travel Size Fragrance Mist
Save 50% Now! Details
In stock - Leaves warehouse in 3-5 full business days Details
- Gift options: See our gifting options Details
Lavishly spray your skin for a light and indulgent aroma of wild dahlia, velvet plum and juicy red currant warmed with notes of black jasmine and spiced vanilla. Our sophisticated new pump delivers great coverage and delicate mist for the lightest most refreshing way to fragrance!
- A rush of wild dahlia & black jasmine wrapped in velvet plum
- Our beautiful, sophisticated bottle features a new travel fragrance pump for a more delicate mist and improved coverage control
- Top Notes: Italian Bergamot, Juicy Red Currant, Baies Rose Orpur, Wild Berry, Golden Delicious Apple
Key Fragrance Notes:
Top Notes: Italian Bergamot, Juicy Red Currant, Baies Rose Orpur, Wild Berry, Golden Delicious Apple
Mid Notes: Velvet Plum, Black Jasmine, Blue Iris Scentrek, White Peach, Wild Dahlia
Dry Notes: Tonka Roasted Absolute, Spiced Vanilla, Velvet Musk, Spun Sugar, Benzoin Laos Orpur