worldwide employed as a crude drug by people in the and Due to the development of antimicrobial resistance by the use of antibiotics among pathogenic bacteria, natural products extracted from the plants can be used as alternative strategies to reduce pathogenic bacteria from foods and patients. the extraction of essential oils from the of , an aromatic from the mountainous of of Sidi Bel-Abbes and the evaluation of their antibacterial against some such E. coli, Ps. 27853 , and , subtilus by using agar well diffusion method and by the study of bacterial growth in the and the of oils.


Different forms of Cockcroft-Walton multipliers are widely used to generate very high voltages in the range of millions of Volts. In many applications, high voltage multipliers are insulated by pressurized gas, to realize compact systems. These systems are often stressed to high operating electric fields and suffer frequent discharges especially during high voltage conditioning phase. During high voltage discharges, transient voltages appear in the system creating higher stresses than normal operation in components. Parasitic capacitance between the high voltage system and ground can significantly affect transients in the system. In this paper, a model for analyzing transients in series coupled high voltage multiplier is presented. Typical transient voltage levels in stage inductors and capacitors are discussed. Experimental results with 1 MV, 100 mA symmetrical Cockcroft-Walton multiplier is presented to corroborate predictions from theoretical model.


This book presents clear and detailed solutions to all problems from the annual F=ma contest hosted by the American Association of Physics Teachers (AAPT) between 2011 and 2019. The competition is the precursor to the USAPhO (United States National Physics Olympiad) and the IPhO (International Physics Olympiad). • Presents scenarios in classical mechanics using pre-calculus, and occasionally calculus, to solve the problems presented in the competitions • Demonstrates a wide variety of exam questions ranging from the simple to the highly complex • Explains how problems can be solved in more than one way when viewed from different angles and using very different approaches F = ma Contests: 2011-2019 Solutions Manual bridges a significant gap in existing literature for competition preparation and is a great resource for students preparing for physics exams and competitions.


Visual object tracking in unmanned aerial vehicle (UAV) videos plays an important role in a variety of fields, such as traffic data collection, traffic monitoring, as well as film and television shooting. However, it is still challenging to track the target robustly in UAV vision task due to several factors such as appearance variation, background clutter, and severe occlusion. In this paper, we propose a novel two-stage UAV tracking framework, which includes a target detection stage based on multifeature discrimination and a bounding-box estimation stage based on the instance-aware attention network. In the target detection stage, we explore a feature representation scheme for a small target that integrates handcrafted features, low-level deep features, and high-level deep features. Then, the correlation filter is used to roughly predict target location. In the bounding-box estimation stage, an instance-aware intersection over union (IoU)-Net is integrated together with an instance-aware attention network to estimate the target size based on the bounding-box proposals generated in the target detection stage. Extensive experimental results on the UAV123 and UAVDT datasets show that our tracker, running at over 25 frames per second (FPS), has superior performance as compared with state-of-the-art UAV visual tracking approaches.


Abstract : Echo-ranging records have been obtained at Perranporth over a period of about one year, some being continuous over several days. Broadly speaking there are three types of trace, all of them at least partly biological in origin: wrigglers, fixed bottom echoes and diffuse patterns. Fish behaviour is displayed continuously out to 40 miles, and is especially complex near dawn and dusk.


Objective: To study the mental health in hyperthyroid patients with diverse personalities. Methods: Seventyfive cases accorded with the inclusion criteria (suffered from hyperthyroidism) were selected. These patients came to consult the advices to doctors in metabolic and endocrinology department from September 2009 to March 2010. They were evaluated the personality and the mental health by the Eysenck personality questionnaire and the Symptom Checklist-90. The results were compared with the normal Chinese and studied the deference of mental health among the diverse personalities. Results: There was a decline in the mental health in hyperthyroid patients. The positive items and the average general score of SCL-90 were higher in hypethyroid patients compared with that of normal control(P 0.05). The general score of SCL-90 and the N score of EPQ demonstrated correlations (r = 0.679,P 0.01). There was no difference in the total score of SCL-90 between the choler and melancholy patients with hyperthyroidism, and between sanguine and phlegmatic patients with hyperthyroidism. The mentalhealth was better in patients of sanguinity and phlegm than that of choler and melancholy. Conclusion: It should be paid more attention in psychologicalintervene to the patients with hyperthyroidism,especially for the cholerandmelancholy patients.


In order to establish a high-frequency regeneration system for rose,the crucial effects of light and plant growth regulators on somatic embryogenesis and plant regeneration in Rosa chinensis 'Yueyuehong'were investigated using leaf as explant. The results showed that after 12 weeks of callus induction on embryo proliferation medium supplemented with 3.0 mg · L-1 2,4-D + 0.5 mg · L-1 TDZ in the dark and a subculture on embryo mature medium under red light(with an intensity of 7.2 μmol · m-2 · s-1)treatment,somatic embryos with thick and expanded cotyledon(s),which had potential regenerating capability were mostly observed. While shoot-like embryos without cotyledon(s)were mostly observed in dark condition.


Humans after finishing their food they spend their time usefully. Thus, they found out many arts and enjoyed it. They not only created art they himself enrolled in it and make others happy. Folk arts have developed with the only intention to make others happy. Then it can be divided into three types. They are folk practices, folk arts and folk science. Karakkatam is one of the very famous art in Tamil Nadu. This article says about karakattam art, its types and its importance with the help of two novels.


Background : The pattern of organisms found in open fractures is important in the selection of antibiotics for prophylaxis and empirical treatment. So far, there is paucity of data on local patterns of bacteria contaminating and infecting open fractures and their antibiotic susceptibility profile. Objective : To describe the pattern and antibiotic susceptibility of bacterial isolates obtained within 24 hours of injury from open fractures and to compare these to bacterial isolates from fractures that subsequently develop infection. Methods : A prospective study of 98 patients with open fractures seen at Kenyatta National Hospital (KNH) within 24 hours of injury between November 2015 and March 2016 was conducted. Swabs for culture and sensitivity were taken from the wounds and antibiotics initiated.Surgical debridement was subsequently carried out witha 14 day follow up for wound infection. Wounds thatbecame infected were sampled for cultures And sensitivity. Results : Fifty-one (52.2%) pre debridement wound samples had positive cultures. Staphylococcus aureus and (Coagulase Negative) CON Staphylococci were the predominant gram positive isolates. At 14 days' follow-up, the infection rate was58.9 %. The predominant gram positive isolate was Staphylococcus aureus . Only 5.7% of the pre-debridement isolates were similar to the post debridement isolates. Conclusions : The contaminating organisms are not similar to the organisms isolated from injuries that later develop infection. Key words: Open fracture, Antibiotics, Infection, Bacterial cultures.


On‐line hemodiafiltration (ol‐HDF) was developed in the 1980s in response to the unmet medical needs observed with conventional low‐ and high‐flux hemodialysis. Firstly, the limited overall efficacy of conventional HD treatment programs as compared to native kidney function has been consistently documented over the broad MW spectrum of uremic toxins as well as fluid volume and hemodynamic control. Secondly, the unphysiological profile of intermittent treatment leading to repetitive dialysis‐induced hemodynamic stress is now a well‐recognized component of cardiovascular disease and end organ damage. Thirdly, the bioincompatibility of patient‐dialysis system leading to dialysis‐induced biological reactions also identified as contributing to dialytic morbidity and mortality. To overcome these limitations and pitfalls, alternative convective‐based therapies (hemofiltration and hemodiafiltration), using higher hemoincompatible membranes and ultrapure dialysis fluid, were proposed as a solution to enhance and enlarge MW spectrum of uremic compounds cleared and to reduce dialysis‐patient biological interactions. In this context, online HDF appeared soon as the best viable and efficient renal replacement modality to cover these needs. Clinical development and implementation of ol‐HDF showed also that dialytic convective dose matters with a threshold point (23 L/1.73 m2 in postdilution mode) to observe clinical benefits and outcomes improvements.


In the holographic dictionary between gauge theory in four dimensions and gravity in five dimensions, there is an encoding in the bulk geometry of the phases of the gauge theory. If the correspondence holds at all scales, it is natural to expect that gauge theory contains information about quantum gravity in one higher dimension. We argue that the confining phase of gauge theory has a correspondence with singularity avoidance in quantum gravity. This comes from the observation that confinement appears to be generically associated with repulsion deep in the bulk on the gravity side, which in turn is a consequence of the violation of energy conditions in quantum gravity that lead to singularity avoidance.


Superconductor/ferromagnetic (SC/FM) Y1Ba2Cu3O7−δ/La0.7Sr0.3MnO3 (YBCO/LSMO) double layers were prepared on LaAlO3 substrates by magnetron sputtering and their electrical and microwave parameters were investigated at 77 K. In the theoretical plan, simple formulas for estimation of the sensitivity of the SC surface impedance to the concentration changes of normal charge carriers were proposed and the surface resistance RS peculiarities of both SC and FM surfaces were described. Thinner YBCO/LSMO structure was characterized by lower SC parameters and higher surface resistance RS at ∼ 4 GHz. The difference of RS of sample SC surfaces was interpreted as due to a difference between the normal charge carrier densities in these samples. RS of the FM surface was higher than that of the SC surface due to the microwave losses of the magnetic subsystem. A peak of the microwave losses, observed in the thicker double layer, was assumed to be caused by uniform FMR in the LSMO film.


Females in some species of Old World monkeys and apes vocalize after copulation, but the function of these vocalizations is not clear. In this article, we examine the hypothesis that copulation calls are a form of postcopulatory female choice. According to this hypothesis, copulation calls are honest signals of fertility (i.e., ovulation) that are used by females to encourage mate guarding by their preferred mating partners and reduce the likelihood of sperm competition. Evidence in favor of this hypothesis is reviewed and discussed in relation to other hypotheses. We suggest that the evolution of female copulation calls in primates is linked to the evolution of other female mating signals such as exaggerated sexual swellings, the potential for sperm competition, and the opportunity for precopulatory female mate choice. Copyright 2005.


Chlorpyrifos 15% granular (15G) insecticide treatments, incorporated into potting soils (0, 2.5, 5.0, 10.0, and 20.0 mg [AI] per cell) in which cabbage and broccoli transplants were grown, were evaluated for phytotoxicity and reduction of damage from field infestations of cabbage root maggot, Delia radicum L., during 1985 and 1986. The 20.0-mg dose was significantly more phytotoxic to both cabbage and broccoli than other treatments. Root ratings of root maggot damage revealed a significant dose-response relationship, with no differences between cabbage or broccoli. The 10.0- and 20.0-mg doses yielded significantly lower root ratings than did the other insecticide treatments. The incorporation of chlorpyrifos 15G into potting soil in which transplants are grown may be an efficacious, economical, and labor-saving procedure for suppression of cabbage root maggot damage to transplanted crucifers.


The six days fasting in the month of Syawal is a voluntary fasting after the 30 days of obligatory fasting in the month of Ramadan. The purpose of this study was to determine the effects of six-day fasting in the month of S y awal on the changes of personality among Muslims. A total of 111 participants comprised of students from Universiti Kebangsaan Malaysia (UKM) and Universiti Malaysia Kelantan (UMK) took part in this study. All participants were Muslims, consisting 91 women and 20 men with age range of 20 years to 53 years old. The analysis method used was multilevel modeling using Hierarchical Linear Modeling (HLM) version 7.0. The LHM was used to test all the hypotheses of the study. The objective of the study was to identify the impact of the S y awal voluntary fasting on the personality change. The findings of this study showed that the quality of S y awal voluntary fasting gives effect to the change of personality which bring significant relationship with both positive and negative personalities. Hence, it can be concluded that the six days voluntary fasting in the month of Syawal contributed to the changes of personality among Muslims. Keywords: Fasting six days in s y aw al ; personality; family; hierarchical linear modeling; muslim


In recent years, internets become more and more popular, and there are many newly life-style rise and develop, especially the change of consumption. In the past, people can get goods only by telephone or go to stores, which usually make people feel troublesome; But now people who want to buy goods can establish contact sellers and get things via only simple order. This research takes APPLE notebook for example, confer what factors and functions could attract consumer to stroll or buy. Therefore, this research combines fuzzy theory, AHP and QFD to analysis the data. The result revealed that the following conclusions: 1. Except price, the attitude of service is the major factor to influence consumers. 2. Except price, the speed of delivery and the quality of things are the second factor to influence consumers. 3. Except price, the after-sale service is the third factor to influence consumers. 4. Except price, the packing of goods is the fourth factor to influence consumers. 5. Except price, the trade credit and bricks and mortar are the last factor to influence consumers.


Metabonomics is a new method for identifing the relationship between organism metabolites and the effect of external stimulates.It provides a new strategy and platform for the TCM study and the modernization of TCM since the main idea of metabonomics is in accordance with that of TCM.


Using the orthoganal design method, the optimum conditions were determined in measuring the contens of n and i paraffins in paraffin waxes by urea adduction. The weight of urea is three times of that of waxes, the weight of activating agent is 18% of that of urea, the reaction time is 2h and the reaction temperature is 25 °C . The method of measuring the contents of n and i paraffins in paraffin waxes by urea adduction under those conditions determined by this paper called modified urea adduction. The results show that the modified urea adduction not only could measure the contents of n and i paraffins in paraffin waxes, but also could measure that in microcrystalline waxes and mixed waxes, the numerical data agree well with that measured by GC.


07–621 De Bot, Kees (U Groningen, the Netherlands; firstname.lastname@example.com), W. Lowie & Marjolijn Verspoor, A dynamic systems theory approach to second language acquisition. Bilingualism: Language and Cognition (Cambridge University Press) 10.1 (2007), 7–21. 07–622 García, Ofelia & Lesley Bartlett (Columbia U, New York, USA), A speech community model of bilingual education: Educating Latino newcomers in the USA. International Journal of Bilingual Education and Bilingualism (Multilingual Matters) 10.1 (2007), 1–25. 07–623 Koutsoubou, Maria (Institute of Education, London, UK), Rosalind Herman & Bencie Woll, Does language input matter in bilingual writing? Translation versus direct composition in Deaf school students' written stories. International Journal of Bilingual Education and Bilingualism (Multilingual Matters) 10.2 (2007), 127–151. 07–624 Saravanan, Vanithamani (Nanyang Technological U, Singapore), Attitudes towards literary Tamil and standard spoken Tamil in Singapore. International Journal of Bilingual Education and Bilingualism (Multilingual Matters) 10.1 (2007), 58–79. 07–625 Serrano, Raquel (Center for Applied Linguistics Washington DC, USA) & Elizabeth Howard, Second Language writing development in English and in Spanish in a two-way immersion programme. International Journal of Bilingual Education and Bilingualism (Multilingual Matters) 10.2 (2007), 152–170. 07–626 Stotz, Daniel (Zurich University of Applied Sciences, Switzerland; firstname.lastname@example.com), Breaching the peace: Struggles around multilingualism in Switzerland. Language Policy (Springer) 5.3 (2006), 247–265. 07–627 Szuber, Anna (Harvard Graduate School of Education, Boston, USA), Native Polish-speaking adolescent immigrants' exposure to and use of English. International Journal of Bilingual Education and Bilingualism (Multilingual Matters) 10.1 (2007), 26–57. 07–628 Tannenbaum, Michal (Tel Aviv U, Israel), Netta Abugov & Dorit Ravid, Hebrew-language narratives of Yiddish-speaking ultra-orthodox girls in Israel. Journal of Multilingual and Multicultural Development (Multilingual Matters) 27.6 (2006), 472–490. 07–629 Vaish, Viniti (National Institute of Education, Singapore), Bilingualism without diglossia: The Indian community in Singapore. International Journal of Bilingual Education and Bilingualism (Multilingual Matters) 10.2 (2007), 171–187. 07–630 Verschik, Anna (Tallinn U, Estonia & U Helsinki, Finland), Multiple language contact in Tallinn: Transfer B2>/A1 or B1>/A2? International Journal of Bilingual Education and Bilingualism (Multilingual Matters) 10.1 (2007), 80–103.


The theory of deterministic model weighting adaptive control is presented and its relation to Multi-model adaptive control is outlined. A pilot process study compares the behaviour of the proposed algorithm to methods such as P1D, dynamic matrix control and adaptive generalized predictive control. Finally an industrial application of the method is described.


Crop model comparisons have mostly been carried out to test predictive ability under previous climate conditions and for soils of the same location. However, the ability of individual agricultural models to predict the effects of changes in climatic conditions on soil-ecosystems beyond the range of site-specific variability is unknown. The objective of this study was to test the predictive ability of agroecosystem models using weighable lysimeter data for the same soil under changing climatic conditions and to compare simulated plant growth and soil-ecosystem response to climate change between these models. To achieve this, data from the TERENO-SOILCan lysimeters-network for a soil-ecosystem at the original site (Dedelow) and data from the lysimeters with Dedelow soil monoliths transferred to Bad Lauchstädt and Selhausen were analysed. The transfer of the soils took place to a drier and warmer location (Bad Lauchstädt) and to a warmer and wetter location (Selhausen) compared to the original location of the soils in Dedelow with the same crop rotation. After model calibration for data from the original Dedelow site, crop growth and soil water balances of transferred Dedelow soil monoliths were predicted using the site-specific boundary conditions and compared with the observations at Selhausen and Bad Lauchstädt. The overall simulation output of the models was separated into a plant-related part, ecosystem-productivity (grain yield, biomass, LAI) and an environmental part, ecosystem-fluxes (evapotranspiration, net-drainage, soil moisture). The results showed that when the soil was transferred to a drier region, the agronomic part of the crop models predicted well, and when the soil was moved to wetter regions, the environmental flow part of the models seemed to predict better. The results suggest that accounting for climate change scenarios, more consideration of soil properties and testing model performance for conditions outside the calibrated range and site-specific variability will help improve the models.


The invention in which the average diameter of the metal particles is from 2 to 7 ㎜, by the average diameter of the pores in the inside or outside of the metal particles used for for artificial marble chips having a foam or open-cell structure of 0.1 to 5 ㎜, the artificial for the marble chips and are uniformly distributed over the entire artificial marble, sikimyeo weight the artificial marble, it relates to the artificial marble and a manufacturing method thereof that improves the surface of the chip leaving a problem.


The collision avoidance strategy for geostationary satellites is discussed in the paper. The
possible encountering objects were first analyzed from the past events and also from the object
population in the geostationary ring. Compared with the conjunctions in LEO, an in-track maneuver
for the collision avoidance has to be planned more carefully, because the satellites have to be kept
inside the control box. To mitigate the high collision risk while keeping the satellites inside the box,
different maneuver strategies were analyzed. Depending on the avoidance maneuver size as well as
the drift time, an appropriate E/W maneuver strategy had to be applied. Another strategy using the
N/S maneuver allows performing larger thrusting without violating the control box; however the
achieved separation varied according to the orbital plane angle and the close approach epoch. The
strategies were finally applied to high risk conjunctions in the past. For all cases, the conjunctions
could be mitigated and the control requirements were satisfied.


Achievement of the skills competency of students in vocational secondary schools is influenced by school and student factors. Learning practices aimed at improving skills competence are determined by the availability of adequate learning facilities. The independence of learning in practical activities affects the achievement of student skills competencies. This study aims to determine the relationship between the learning facilities readiness and the independence learning on student skills competencies. The study was conducted since the decreasing level of student learning independence and the study of learning facilities that were considered inadequate. Measurement of independent variables is done using questionnaires while dependent variables measured through student grade of subjects that hold practical learning. The research was conducted with a quantitative approach descriptive expost facto method. The population were students of Industrial Automation Engineering Department at SMK Negeri 1 Singosari Malang Regency. The study resulted that the relationship between the availability of learning facilities and skills competencies of 45.50%, between learning independence and skill competencies as big as 19.32%, and the relationship between both independent variables to the dependent variable is 64,82%. It is concluded that the availability of learning facilities and independence study have a significant contributions to students' skills


Research paper written by Laurelle Patricia Dunsavage for an American History Class at Marfa High School on March 3, 1977. It is about different types of healers in the hispanic culture and has a section defining the different herbs and their uses in remedies. Samples of the actual herbs are included in this report.


An interactive program developed for the MATLAB environment is presented to assist students in learning structural dynamics. The program is intended to supplement lectures and textbooks by providing a tool for students to observe the effect of parameters on dynamic systems. The functions of the program include plotting the response of a single degree of freedom system subjected to a variety of dynamics loads. The forcing functions can be applied directly on the mass or as support motion. In addition other insightful plots can easily be accessed through the program interface, such as the transfer function and Fourier Transform of the excitation force. The graphical interface is designed to be intuitive and emphasizes simplicity in using the program, obtaining plots and more importantly, comparing results. In analyzing the response of structures due to support excitation, the program makes use of a unique relationship that exists between the support motion and response type. A formulation is derived for the support impulse response function that, when convolved with the excitation, results in function that relates the input type to the output type. Inputting displacement results in the displacement response while an input acceleration record will produce the acceleration response. Thesis Supervisor: Eduardo Kausel Title: Professor of Civil and Environmental Engineering _L~~ __~ ~ ___X__ll__1__1_11 _I__LLXI-I .~~ll~.


The pathogenesis of B‐cell lymphoproliferative disorders in general and B‐cell chronic lymphocytic leukaemia in particular appears to involve dysfunctional regulation of humoral and cellular immunity with the subsequent development of genetic aberrations in B cells. In theory, either component may arise de novo or may be influenced by environmental exposures including infectious agents, antigens, genotoxic chemicals, or radiation. As an intermediary within the exposure‐disease continuum, monoclonal B‐cell lymphocytosis may be a helpful biomarker for teasing out these various contributions to risk. This article introduces a series of papers that resulted from an International Workshop held in May 2007 entitled 'Monoclonal B‐cell Lymphocytosis and Chronic Lymphocytic Leukemia: Environmental and Genetic Risk Factors'. Research efforts, such as those described in this issue, should lead to improved interventions, more predictive biomarkers, more effective treatments, and a greater appreciation of how the immune system functions over the entire human lifespan.


OBJECTIVE: To review clinical, etiological and diagnostic characteristics of the 22q11 deletion syndrome and its as-sociation with congenital heart defects. DATA SOURCES: Medline, Lilacs and SciELO databases were searched from 1980 to 2009 using specific descrip-tors as "22q11", "DiGeorge syndrome", "velocardiofacial syndrome", "congenital heart defects" and "cardiovascular malformations". DATA SYNTHESIS: Heart malformations are the most fre-quent congenital defects at birth and represent an important Public Health problem. The 22q11 deletion syndrome, also called DiGeorge syndrome, velocardiofacial syndrome and CATCH22, stands out as one of the main known causes of congenital heart defects. This is an autosomal dominant genetic disease characterized by a highly variable phenotype, which renders its difficult clinical identification. In addition, the majority of the patients present a microdeletion identified mainly by molecular cytogenetic techniques as fluorescent in situ hybridization, which are rarely available in Brazil. Similarly to other syndromes, 22q11 deletion syndrome is associated to some specific heart defects, espe-cially conotruncal. It is still not clear which patients with congenital heart defect should be screened for 22q11 dele-tion syndrome. CONCLUSIONS: Cardiologists and cardiac surgeons, particu-larly the pediatric ones, must be aware about the features and health care related to 22q11 deletion syndrome. Subjects with the syndrome very often present abnormalities of mul-tiple systems, that could result in difficulties and complica-tions during their clinical and surgical course.


Topical issues of certification of police officers have been considered. The approaches of scientists to the definition of such concepts as "certification" of police officers have been studied. The views of scientists on the institute of certification, its legal regulation and the expediency of conducting have been analyzed. The history of the certification procedure and the grounds for its application have been considered, the main characteristics of the attestation and types have been clarified. The purpose of certification is seen in the most rational use of personnel, increasing the efficiency of their work.
It was found that the definition of "certification" of police officers was first enshrined in law during the reform of the law enforcement system. Certification of police officers is enshrined in the new Law of Ukraine "On the National Police" from July 2, 2015 № 580-VIII, on the basis of which a new body was established, that is the police.
Police certification is considered a professional standard and one of the important criteria in police service. Certification has no periodicity and has a special subject. We consider the desire for openness and transparency of its conduct to be positive in the police certification procedure. Three types of police certification have been studied. An exhaustive list of types of certification has been established.
Based on the analysis of the legal regulation of the procedure of certification of police and scientific views of scientists, the definition of " certification " has been defined and characterized. The materials of the judicial practice on appealing the decisions of the certification commissions of the National Police bodies on dismissal of police officers as a result of their failure to pass the certification in Ukraine have been studied. The current state of legal regulation of the procedure of certification of police officers in Ukraine has been analyzed, its positive and negative aspects have been clarified.


Companies have to focus on their customers to stay competitive in the future. Therefore, metrics are necessary to measure the performance of production plants. Based on the TPM approach a metric is introduced in this paper which includes the market. This is done by taking only the produced products into account which fulfill a customer order. Products produced on stock are excluded. As a result the new metric is suitable as a performance measurement in production plants because it supports on the one hand the management objective of optimizing quality rate, performance rate and availability of the equipment. And on the other hand the management has to adjust the loading time on the customer demand. A numerical example emphasis the major drawbacks of the classical TPM metrics and illustrates the advantages of the presented performance metric.


The hazard analysis for the Vrancea subcrustal earthquakes in Carpathian Mountains, Romania, include relationships for the recurrence of magnitude and directional attenuation functions for the ground acceleration. Sensivity of results to the maximum credible magnitude of the source and to the maximum recorded ground acceleration is discussed. 1 Recurrence magnitude relationships The major contribution to seismic hazard in Romania comes from Vrancea seismogenic zone, located where the Carpathian Mountains arc bends. The both historical and instrumental Catalogues of Vrancea events use, the GutenbergRichter magnitude, M (Gutenberg Richter, 1954). As a systematization requirement, the Global Seismic Hazard Assessment Program in Europe (GSHAP, 1993) promoted at the GeoForschungsZentrum, Potsdam, Germany, recommends the use of the moment magnitude Mw. For the subcrustal Vrancea earthquakes, the following magnitude conversion relationship may be obtained from the linear regression of available records during the 60yr.: Mw = 1.09 M 0.36 (1) where: M is the Gutenberg-Richter magnitude and Mw is the moment magnitude. The Gutenberg-Richter law for the recurrence of earthquakes with magnitude equal to and greater than M is determined from the Radu's catalogue of Vrancea intermediate depth magnitudes (M≥5.0) occurred during this century (1901-1994). It contains 103 seismic events. The average number per year of Vrancea earthquakes with magnitude ≥ M, as resulting also from Fig.1, is (Lungu et al, 1995): log n(≥M) = 3.49 0.72 M (2) The Hwang and Huo (1994) modification of the Gutenberg-Richter relationship: 1 e n(≥M) = e ———————— (3) 1 e was determined for the Vrancea source as (Elnashai, Lungu, 1995): 1 e (7.8 M) n(≥M) = e ———————— (4) 1 e (7.8 6) where the threshold magnitude was selected as M0=6.0,. the maximum credible magnitude of the source was selected as Mmax=7.8, and 8.036 = 3.489 ln10 and 1.658 = 0.720 ln10. The magnitude recurrence relationship depend on the magnitude intervals it refers, such as, the threshold magnitude calibrates the coefficients of recurrence expression (2). Although an exact estimation of the maximum credible magnitude of the source can not be done, even an approximate estimation of it has very important numerical consequences on the prediction of magnitude having large recurrence intervals. The maximum credible magnitude of the Vrancea source was estimated in the past to be at most M=8.0 and at least M=7.5. Marza, Kijko and Mäntyniemi (1991) estimate as "reasonable and stable" a maximum magnitude of the source Mmax = 7.8, (standard deviation) of 0.2. According to the same authors, the strongest experienced Vrancea earthquake is the 1802 event with a magnitude of M = 7.7 ± 0.3. ICOSSAR'97, Kyoto, Japan Nov. 24 28, 1997


Objective:To develop methods for the determination of tripterine and Tripterygium wilfordii total triterpenoids in Tripterygium wilfordii preparations. Methods:The UHPLC analysis was used with an BEH C18 column (1.7μm,2.1×50 mm) ,using methanol-1%HAc (70:30) as mobile phase. The detection wavelength was 250nm and the flow rate was 0.4mL/min. A colrimetric method was established for the essay of the total triterpenoids with Vanillin-HAc-Perchloric acid as the coloring reagent and measuring of the absorbance at 425nm. Results:The calibration curves were linear in the ranges from 5.0 to 80.0μg/mL (r=0.9996) for tripterine with UHPLC and from 20.0-100.0μg/mL (r=0.9989) for the total triterpenoids (calculated as tripterine) with colorimetric method. The average recoveries (n=9) were 99.01% and 99.86%,respectively. The contents of tripterine and tripterygium total triterpenoids of the OTC Tripterygium preparations were found to be in the range from 19.54-772.64μg/tablet and 4.27-8.90mg/tablet,respectively.Conclusion:Both methods were found to be accurate and reliable with very good ruggedness. They can be used for the assay and quality control of the Tripterygium wilfordii preparations. The contents of tripterine and Tripterygium wilfordii total triterpenoids of the OTC Tripterygium wilfordii preparations were found to be in great diverse. In order to make safe and effective usage of the drug,much more attention should be paid to their quality control.


Snow is of great economic and social importance for the European Alps. Accurate monitoring of the alpine snow cover is a key component in studying regional climate change as well as in daily weather forecasting and snowmelt run‐off modelling. These applications require snow cover information on a high temporal resolution in near‐real time. For the European Alps, operational snow cover fraction maps are generated on a daily basis using data from the Advanced Very High Resolution Radiometer (AVHRR) on board the National Oceanic and Atmospheric Administration (NOAA) platforms. Snow cover distribution is inherently discontinuous and heterogeneous in this mountainous region. We have therefore implemented a straightforward multiple endmember unmixing approach to estimate fractional snow cover. Subpixel proportions are difficult to validate because similar products are not available and appropriate ground‐based observations do not exist. In this study, we validate AVHRR subpixel snow retrievals using binary classified data sets from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) to establish absolute errors of our operational approach at three test sites. Our analysis indicates that the AVHRR subpixel maps compare well with the aggregated ASTER data, showing an overall correlation of 0.78 and providing subpixel estimates with a mean absolute error of 10.4% fractional snow cover. Discrepancies between AVHRR and ASTER snow fraction maps can be attributed to varying snow conditions, terrain effects and density in forest cover.


Author: Sanna Ruusunen Subject: Inbound logistics outsourcing in electrical solutions providing company Year: 2018 Place: Helsinki Master's Thesis. Lappeenranta University of Technology, School of Engineering and Science, Industrial Engineering and Management. 103 pages, 4 tables, 6 figures and 3 appendices Supervisors: Professor Timo Kärri & Post-Doctoral Researcher Ari Happonen


This document describes a kind of system, including a kind of active circuit, which is configured to generate the signal of instruction alert if.Residual current device trigger circuit is coupled with active circuit and residual current device.Residual current device trigger circuit is configured to provide for simulation earth leakage current condition, triggers residual current device when receiving alert if indication signal.


The radio interference calculation described pertains to distributed, conductor-generated corona, although it can be adapted to discrete noise sources as well. The results of the calculation give noise levels on a relative basis only but permit a comparison of several proposed designs with existing lines of known performance. The problem has been treated in three steps as follows: the solution of the noise generation density on the surface of each conductor; the solution of the total noise voltage on each conductor due to distributed noise generation on that and other conductors; and the solution of the field intensity at the ground surface due to noise voltages on all conductors. The general form of the analysis, some interesting aspects of the computer solutions, and some typical results are discussed.


[1993] A.C. 534 in support of this proposition. In the first of these cases Lord Goff said that he conceived it to be his duty to interpret the law in accordance with the Convention "when I am free to do so", and he then concluded with satisfaction that the existing law on breach of confidence was already consistent with the Convention. Lord Keith in the Derbyshire case applauded these sentiments, and again pronounced himself satisfied that the common law accorded with the Convention in not allowing a local authority to maintain an action for defamation. But can it really be said that these remarks are authority for effecting a change in the common law when it is found not to be consistent with the Convention? Can alteration of a principle clearly laid down in previous cases really be justified under the banner of "articulation"? After referring to the European Court of Human Rights cases of 1979 and 1991 involving The Sunday Times, the Court of Appeal concluded that the requirement in article 10(2) that any restrictions on freedom of expression should be "prescribed by law" and "necessary in a democratic society" was not satisfied by the "almost limitless discretion" of a jury to award damages. The common law "if properly understood" required the courts to subject large awards to a more searching scrutiny than had been customary, and the test for intervention should now be a lower one: "Could a reasonable jury have thought that this award was necessary to compensate the plaintiff and to re-establish his reputation?" In Miss Rantzen's case, a reasonable jury could not have thought this. The court rightly rejected the suggestion that awards in personal injury cases could be used as guidance in an action for defamation, and also said that juries should not be referred to jury awards in previous defamation cases. But, it opined, as awards substituted by the Court of Appeal under section 8 accumulate, these ought to provide satisfactory guidance for juries and should be citable. This sensible suggestion would carry more weight if the Court of Appeal had devoted more than one brief paragraph to explaining why it felt £110,000 to be a more appropriate figure for "a terrible ordeal" (but one after which Miss Rantzen remained "a distinguished and highly respected figure") than £250,000.


typical of prosperity, full employment, and rapid overall growth. Harry Johnson and others argued long ago, however, that general equilibrium theory yields no such clear-cut answer. The bias in productivity growth becomes absolutely critical. Professor Mintz draws on eight decades of United States experience to test these hypotheses. The results are comforting but in few cases are they surprising. First, the author explores the association between American exports and world imports. The analysis reveals considerable conformity, but with the degree of conformity (and degree of export instability) increasing as we move further into the twentieth century. Second, we discover domestic demand asserting an important influence over exports and in a manner opposite to foreign demand. It appears that exports were aided by domestic contraction while hindered by expansion, thus supporting the traditional view. In short, the depressing effect of domestic expansion was diminished but not fully offset by the stimulus offered by rising foreign demand. Finally, Professor Mintz notes that goods with elastic supply have increased in importance in the American export bundle. As a result, the impact of domestic activity on exports has diminished in modern decades. Although these results are perfectly reasonable, one cannot help but ponder if the same conclusion would be forthcoming if the NBER cycle framework were set aside in favor of more conventional econometric technique. JEFFREY G. WILLIAMSON, University of Wisconsin


In the 'Proceedings of the Royal Society' (xviii. p. 362, xix. p. 73) are some observations by the late Count Wollowicz and myself on the effect of alcohol, brandy, and claret on the elimination of nitrogen. As the experiments were on one man, I have taken an opportunity of repeating them on another person; and as the late observations of Dr. Austin Flint (junior) on a man who walked 317 miles in five days have appeared to some persons to run counter to the now generally accepted view that exercise produces either no change or only insignificant changes in the urea, I have combined experiments on exercise with those on alcohol. With respect, however, to Dr. Austin Flint's experiments, it would appear that while the egress of nitrogen was determined with the greatest accuracy, the amount taken in was for the most part merely estimated by reference to Payen's Tables, and therefore there is no certainty that the ingress was what it is assumed to have been. The food also was very varied, so that the difficulty of properly estimating the nitrogen was still more increased. The following experiments were made on a soldier, W. D., aged 30. I He is a powerfully built man, 5 feet 6 inches in height, and measuring 40 inches round the chest. As a young man, he had been employed in a distillery near Glasgow, and at that time drank largely of whisky, some times taking half a piut before breakfast. For the last ten years, since he t has been in the army, he has been very temperate, taking chiefly beer in moderate quantities, and only occasionally spirits. He bears the character of a very steady soldier, and has always had perfect health, with the exception of an attack of "spotted typhus" six years ago. He has never served abroad.


We study predictive control in a setting where the dynamics are time-varying and linear, and the costs are time-varying and well-conditioned. At each time step, the controller receives the exact predictions of costs, dynamics, and disturbances for the future $k$ time steps. We show that when the prediction window $k$ is sufficiently large, predictive control is input-to-state stable and achieves a dynamic regret of $O(\lambda^k T)$, where $\lambda<1$ is a positive constant. This is the first dynamic regret bound on the predictive control of linear time-varying systems. Under more assumptions on the terminal costs, we also show that predictive control obtains the first competitive bound for the control of linear time-varying systems: $1 + O(\lambda^k)$. Our results are derived using a novel proof framework based on a perturbation bound that characterizes how a small change to the system parameters impacts the optimal trajectory.


In this paper, numerical and experimental studies for crack detection of structures using "element stiffness index distribution" are presented. The element stiffness index distribution is defined as a vector of norms of sub-matrices corresponding to element stiffness matrices calculated from the reconstructed global stiffness matrix of the beam. When there is a crack at an element, the element stiffness index of that element will be changed. By inspecting the change in the element stiffness index distribution, the crack can be detected. A significant peak in the element stiffness index distribution is the indicator of the crack existence. The crack location is determined by the location of the peak and the crack depth can be determined from the height of the peak. The global stiffness matrix is calculated from the measured frequency response functions instead of mode shapes to avoid limitations of the mode shape-based methods for crack detection. Numerical simulation results for the cases of beam-like structures are provided. The experiment is carried out to justify the efficiency of the proposed method.


The German-Swiss natural scientist, politician and emigrant Carl Vogt was a pioneer of science education of the public in the nineteenth century. Among his most important popular writings are his travel reports, Ocean und Mittelmeer (1848), in which he dealt with his research into marine biology in France and Italy (1844-1846) as well as with art, culture and science in these two countries. His travel reports illustrate the considerable interest in biological education in the contemporary literary public and the growing educational value of the natural sciences, which became a firm element of Wilhelmine culture. Vogt studied the "physiology of the lower animals" and searched--similar to the functionalist view of organisms in Georges Cuvier and his sponsor Henri Milne-Edwards--for a causal link between the morphological structure and the physiological functions, the "vital mechanics" ("Lebensmechanik"), of animals. Vogt's travel reports were influential for the contemporary popular "seaside studies".


From 1980 through 1982, intravenous extracranial digital subtraction angiography (DSA) was performed in 6684 patients at the Cleveland Clinic. Of these, 211 previously unoperated patients had prior transient ischemie attacks (TIA) or strokes in conjunction with >50% carotid stenosis on unequivocal DSA studies. Nonopcrative management was employed in 126 patients, including 120 (84%) who received antiplatelct therapy or formal anticoagulation. The remaining 85 patients underwent carotid endartercctomy. During a mean follow-up interval of 36 months, there was no overall difference in survival, late TIA, or stroke between the nonoperated and surgical cohorts. However, parity was maintained in these groups only because of the prevalence of intermediate (50–69%) stenotic lesions and stable internal carotid occlusions in the nonoperated group. Carotid endarter-ectomy provided superior stroke prevention for patients with >70% unilateral stenosis (p = 0.04), for those with >50% bilateral stenosis (p = 0.004), and for those with internal carotid occlusions associated with >50% contralateral stenosis (p = 0.03). The special risk of such discrete subsets should be recognized in order to plan appropriate treatment at the present time, as well as to conduct safe clinical trials in the future.


Optical magnetic field (current) sensors have recently reached practical application. This paper reports on evaluations of LPE garnet (TbY) IG crystals for magnetic field sensors, and on their optical characteristics. 100 ¿m thick films were produced on {111} GGG substrate, but pits appeared even when using a Pbo/B2O3 melt with a low 6.0 molar ratio. We studied the sensitivity and linearity of the Faraday rotation of these LPE films.


The equivalende of two stability criteria (decreasing pressure with increasing radius versus increasing central density with increasing mass) is shown analytically for spherical polytropes without background medium, and numerically for embedded ones. Previous results concerning the instability under external pressure of incomplete (truncated) polytropes within a uniform background medium are shown to be not true. The spherical incomplete embedded polytrope is stable/unstable for the same polytropic indices and for the same background densities as the corresponding compete embedded polytrope.


This article analyses the trends and problems associated with the peculiarities of the development of nuclear energy in France. This country has always paid particular attention to the fuel and energy sector. Its significant potential allows it to occupy one of the top places in the world in the use of nuclear technologies in the national economy. At the same time, the relatively hostile policy of the European Union concerning nuclear energy in connection with the implementation of its course on the "green" economy creates many problems in the relations of Paris with the leadership of this integration association. Given that Germany in 2022 completely closes its nuclear power plants (NPP), and France becomes the leading country in the EU for the use of nuclear energy, the leadership of this country under the influence of political factors often has to make mutually exclusive decisions in this area. France's position as the most significant nuclear power in the EU is complicated because it faces increasing competition in the global nuclear market. The leading positions on it are traditionally occupied by the United States, Russia, and China. Time will tell whether France will be able to cope with these threats. One thing is certain: France seeks to maintain and strengthen its position as the leading nuclear power in the EU and worldwide. France's long-term experience in designing and building nuclear power plants and ensuring their safe operation can also be useful for Russia, as it is generally recognized that our country has been and is one of the world leaders in nuclear energy.


The role of knowledge and technology transfer between academia and the industry has received increasing attention in the analysis of innovation. This article aims to explore the scientific literature concerning knowledge transport mechanisms and describe how the topic was organized by previous studies and terminologies applied. A systematic review was conducted in which the content of recent contributions best fitting these intensions was analysed. The characteristics of knowledge, individuals, organizations, and disciplines were found to be the main determinants in the adoption of transfer mechanisms. These were classified in terms of formalization, relational involvement, direction, and time. On the revealed multi-dimensionality of knowledge transfer and complementarity between transfer activities we framed a new taxonomy distinguishing between channels and processes. Future research may deepen these factors, such as the economic aspects driving the adoption of transfer mechanisms informing decisions on the funding of innovation.


Serum contains a growth factor derived from platelets and also growth factors derived from platelet-poor plasma. Extracts of heated (1000) human platelets function synergistically with platelet-poor plasma to induce DNA synthesis in quiescent, density-inhibited BALB/c 3T3 cells. Platelet-poor plasma alone did not induce DNA synthesis. Cells exposed to platelet extracts became competent to enter the cell cycle, but the rate of entry into the S phase depended upon the concentration of platelet-poor plasma. The time required for the induction of this competent state was a function of the concentration of the platelet extract. A 2-hr exposure to 100',g of the platelet extract at 370 caused the entire cell population to become competent to enter the S phase. At 40 or 250 the cells did not become competent to synthesize DNA. The platelet extract-induced competent state was stable for at least 13 hr after removal of the platelet extract; however, in the absence of platelet-poor plasma, these competent cells did not progress through the cell cycle. The addition of an optimal concentration of platelet-poor plasma (5%) to these competent cells initiated cell cycle traverse with a ra id, first-order entry of cells into the S phase beginning 12 hr after addition of the plasma. The addition of a suboptimal concentration of the plasma (0.25%) did not increase the rate of cell entry into the S phase. Thus, the induction of DNA synthesis in quiescent BALB/c 3T3 cells can be resolved into at least two phases, controlled by different serum components: (i) competence, induced by the plateletderived growth factor; and (ii) progression of competent cells into the cell cycle, mediated by factors in platelet-poor plasma. The growth of 3T3 cells (1), diploid fibroblasts (2), and smooth muscle cells (3) in vitro is controlled by the concentration of serum in the medium. Serum can be separated into two sets of components which control different cell functions. One set maintains cell viability (4), while the other stimulates replication (5). A heat-stable (1000) cationic growth factor (6) derived from. platelets (7) is released into serum during the clotting process (8, 9). Human serum contains about 770 pg of this polypeptide growth factor per mg of protein, as demonstrated by radioimmunoassay (7). Defibrinogenated platelet-poor plasma, a fraction prepared from unclotted blood, contains only low levels of the growth factor and does not stimulate the replication of diploid fibroblasts or BALB/c 3T3 cells (3, 7-9). Platelet-poor plasma does, however, contain the factors that maintain cell viability (3). The process by which resting cells become committed to enter the growth cycle remains unclear. Smith and Martin (10) have proposed that the commitment of quiescent cells to synthesize DNA is a random event characterized by a first-order rate constant, the transition probability. According to this The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 U. S. C. §1734 solely to indicate this fact. 4481 model, the "initiation of cell replication processes is random, in the sense that radioactive decay is random" (10). Brooks (11, 12) has tactically used serum as a single component and has published data that support the transition probability model of the cell cycle. Serum was interpreted to induce cell cycle traverse by increasing the transition probability. The 12to 14-hr lag period required for serum to induce DNA synthesis in a resting population was suggested to be the interval needed to increase the transition probability for commitment (12). The commitment of a quiescent population of cells to initiate DNA synthesis was found to occur gradually over a period of time that even exceeded the lag period for entry into the S phase (12). Single cells were felt to become committed to synthesize DNA less than 5 hr before the S phase (after a 7to 9-hr lag period), because the withdrawal of serum before this time prevented the replication of DNA (12). The randomness, the lack of synchrony, and the delay in commitment make biochemical analysis of the cell cycle difficult. Since serum contains both platelet-derived growth factors and plasma-derived viability factors, we have reevaluated the commitment process. Using brief exposure to heated platelet extracts followed by transfer to platelet-poor plasma, we now show that the process by which cells leave the quiescent state (Go) and enter the cell cycle can be resolved into at least two discrete stages which are controlled by separate serum components. The first stage, termed competence, is a prerequisite for entry into the growth cycle. Competence is mediated by a polypeptide derived from platelets and may occur rapidly. The second stage, progression, controls the entry of competent cells into the growth cycle. Progression is controlled by factors in platelet-poor plasma. MATERIALS AND METHODS Cell Culture. BALB/c-3T3 cells (clone A31) were plated in 0.3-cm2 microtest wells (Falcon; approximately 1000 cells per well) in Dulbecco's modified Eagle's medium (Flow Laboratories) supplemented with calf serum (Colorado Serum Co.) to 10% and incubated for 6 days at 370 to reach confluence. The spent medium was removed; serum, platelet extract, or platelet-poor plasma was added and the cells were incubated at 4, 25, or 370, as indicated. The serum (or serum components) was removed after various time periods and the cells were rapidly washed with 28 mM 2-mercaptoethanol in modified Eagle's medium followed by a wash with modified Eagle's medium alone. Medium containing platelet-poor plasma and [3H]dThd (5 MCi/ml; 6.7 Ci/mmol) (New England Nuclear) was then added and the cells were incubated at 37°. At appropriate times the cells were fixed with methanol, washed twice with 5% trichloroacetic acid, and processed for autoradiography (6). Between 500 and 1000 cells were scored for each point. D ow nl oa de d by g ue st o n S ep te m be r 16 , 2 02 1 4482 Cell Biology: Pledger et al.


The important advancement which has taken place during the last decade in the process of the creation of a society with progress without precedent throughout history, has led to a quasi generalized economic and financial crisis that has ended by stirring up the very foundations of our life in society. These achievements that have been attained are the result of a whole conglomerate of effort carried out by the most diverse classes, with the common denominator of freedom in stability. The development of research in the different spheres of knowledge, in our opinion constitutes one of the fundamental axes around which the progress attained has revolved. This progress can be seen today as menaced by the ghost of the crisis, which is hitting, particularly all the under privileged, so hard. Nevertheless, we feel that the problem which has caused so much concern to so many families cannot be reduced solely to the economic-financial sphere but it must also be considered as a consequence of another far deeper and extensive problem: this is a crisis of values. In fact, historical evolution has accumulated a considerable residue of knowledge supported on certain principles that were believed unchangeable. The explosion of the economic-financial crisis has brought to light the fragility of our social systems, in such a way that we are becoming aware of the disappearance of these principles and, what is far most serious is the lack of any that substitute them. The result is disorientation in all


The anionic mixed species [trans-Pt(C6F5)2(C⋮CtBu)2]2- reacts with TlNO3 to yield the heteropolymetallic compound [PtTl2(C6F5)2(C⋮CtBu)2] (2). The X-ray crystal structure of its adduct {2(acetone)2}n shows its polymeric nature, giving the first example of a polymeric Pt(II)−Tl(I) complex stabilized by alkynyl−thallium and platinum−thallium bonding interactions. In the solid state, both 2 and the precursor (NBu4)2[trans-Pt(C6F5)2(C⋮CtBu)2] (1) exhibit photoluminescence at room temperature.


It is proposed a modification of the "piramidal" algorithm of small time series forecasting "Piramidal" approach was developed in recent years, numerical results show advantages of this method in comparison with known approaches to extrapolation, based on the using of polynomials, including Newton's extrapolation But this approach was tested only on deterministic time series In this paper piramidal approach is applied to construct prognoses in the case where the time series contains a random component It is studied the procedure for constructing the forecast value in accordance with the pyramidal method and improved the main criteria of this method The main idea of the method improving is to find special patterns in the table of finite differences The improved method is used for the number of patients with COVID-19 forecasting in Ukraine © 2021 Copyright for this paper by its authors Use permitted under Creative Commons License Attribution 4 0 International (CC BY 4 0) CEUR Workshop Proceedings (CEUR-WS org)


Indonesia is the biggest archipelago country. Unfortunately, the result of national development has not yet evenly distributed to remote islands along the borderlines. To find out the cause, a qualitative research should be conducted. It focuses on the local potentials, economic condition, socio-culture, local wisdom, and national defense. The result of this study shows the potentials of Nunukan and Sebatik Regency are agroindustry (plantation and forestry), oceanography, international trade, mining, port service, and tourism. The economic condition of Nunukan Society is developed enough, while Sebatik is still left behind. Their employement includes trading, gardening, fishing, farming, private and civil service. The socio-culture condition consists of various ethnics such as Dayak, Tedung, Bugis, Jawa, and Nusa Tenggara Timur (NTT). Those areas are open for newcomers. The local wisdom refers to traditionally managing natural resources. Their nationalism is strong enough and none becomes Askar Wataniah. The security issues that needs more attention include illegal logging, fish theft, robbery on sea, drug abuse, and illegal tresspassing.


Based on the modern achievements of the national science in criminal procedure and the development of the theory of evidence in criminal proceedings, in particular, its standardization, the author examines the theoretical prerequisites for standardization of evidence by an investigating judge when considering requests for permission to conduct procedural actions. The following conclusions are emphasised: 1) the concepts of functions and powers of an investigating judge are multilevel, and powers are of optional, auxiliary significance in relation to the function. The function of judicial control finds its practical implementation through the formal existence of a certain range of powers of the investigating judge and through their exercise during criminal proceedings; 2) the consideration of requests for permission to conduct procedural actions is a type of powers of the investigating judge aimed at exercising the function of judicial control over the observance of the rights, freedoms and interests of persons in criminal proceedings; 3) the consideration of requests for permission to conduct procedural actions is carried out in the form of evidence, which is standardised by the legislator; 4) standards of proof are a set of rules that must be followed by the subject of criminal proceedings and ensure that he or she has the level of conviction necessary to make a lawful and reasonable decision; 5) when considering requests for procedural actions (depending on the type of procedural action), the investigating judge must be guided by the following standards of proof: reasonable grounds, reasonable suspicion; beyond reasonable doubt; 6) the guidelines for the application of the "beyond reasonable doubt" standard by the investigating judge when deciding on the choice of preventive measures are not directly provided for by law, but follow from the nature and objectives of this procedure.


Smart TV means a multi-purpose TV that can go beyond conventional TV functions and enable the Internet and various application programs. Smart TV is expected to play a more important role in the era of Internet of Things. In this study, the design guidelines of GUI for smart TV are focused on the aspects of visibility and operability among various consideration. In terms of visibility, we considered the size of icons which are displayed on TV. In terms of operability, we considered manipulation of the pointer which is appeared on the TV screen. The guidelines presented in this study are not a result of conducting separate experimental studies, but an applied result based on existing research results and scientific/engineering rules.


Based on the experiences from the anti-seepage strengthening treatment made on the small and medium sized earthfill dams with the technology of jacket well backfill in recent years within Quzhou,the key problems from the construction and the quality control are analyzed and discussed,and then the standards for both the technology and quality control of the construction of the clay impervious wall filled with the jacket well backfill technology for the risk elimination and strengthening of small and medium sized reservoirs are put forward.Furthermore,the combination of both the technologies of jacket well backfill and grouting and the treatments on the faults from the construction of the jacket well backfill are analyzed and the relevant suggestions are given as well.


A simple method of successive ionic layer adsorption and reaction(SILAR) was employed to prepare SnS sensitized nanocrystallite TiO2 photoanodes.The characteristics of these photoanodes,such as surface morphology,crystal structure,UV-Vis adsorption and diffusion properties,were measured with XRD,TEM,UV-Vis adsorption and diffusion spectra,respectively.The photovoltaic performances of SnS sensitized solar cells with these photoanodes were measured.The effects of counter electrodes with polyaniline or platinum catalyst and liquid electrolytes with iodine or sulfur redox couple on the photovoltaic performance were also studied.The cells assembled with these different components showed different photovoltaic performance.It was found that the cell assembled with the photoanode fabricated by 9 times of SILAR circulation,the counter electrode with polyaniline-stainless steel net,and the liquid electrolyte containing sulfur redox couple showed the highest photovoltaic performance.The short-circuit current density,open-circuit voltage,fill factor,and power conversion efficiency could reach 4.59 mA/cm2,0.547 V,0.505 and 1.27%,respectively.


ALTHOUGH ANA MARIA MATUTE varies her subject matter and experiments with style in her novels, she remains consistent in the expression of a uniquely personal world; she herself has stated that it is the duty of the novelist to express his own concept of the world through his characters and works.' Those who have followed this author's career are constantly delighted by her inexhaustible originality of form, but it has become apparent that she has chosen a limited number of symbolic situations and types as the best means of conveying her message. Among the basic themes of paramount importance in her novelistic production, Eugenio de Nora has noted (1) loneliness or lack of communication, (2) a mixture of love and hatred between brothers, lovers or friends, and (3) the necessity of escaping from life.2 I would add to these the inno-


The effects of metal ions on #beta3-N-acetyl-D-glucosaminidase (NAGase,EC184.108.40.206) from Helicoverpa armigera have been studied.The results show that Na~(+),K~(+) and Li~(+) ions have no effect on the enzyme activity.Mg~(2+) and Ca~(2+) ions have few effects on the enzyme activity, while Zn~(2+),Cu~(2+) and Al~(3+) inhibit the enzyme. The inhibitory kinetics of Cu~(2+) and Al3+on the enzyme was further studied. The results showed that Cu~(2+) was a reversible inhibitor of the enzyme and the inhibition was determined to be of mixed type. The inhibition constants of free enzyme (K_(I)) and enzyme-substrate complex (K_(IS)) are determined to be 0.23 mmol/L and 1.49 mmol/L, respectively. Al~(3+) is a reversible competitive inhibitor of the enzyme, and the inhibition constants (K_(I)) was determined to be 6.42 mmol/L.


Breast cancer is the second largest death in women. One of the preventions of breast cancer by early detection is Breast Self-Examination (BSE). It aims at finding out abnormal lumps in the breast. There were 20 cases of breast cancer in Palu in 2017, 10 of them died, then increased in 2018 to 25 cases, and 14 died. Based on preliminary research at Senior High School of SMA 7 Negeri Palu, in 2021, there was 1 case of breast cancer. This research aimed to determine the correlation between knowledge, attitudes, information exposure, parental support, and Breast Self-Examination (BSE) behavior. This was quantitative research with a cross-sectional approach. The samples were taken through the Slovin method with the Proportional Stratified Random Sampling technique. The total population was 396 students, and the total samples were 80 students. The majority of respondents are 17 years old, namely 52.5% with good behavior, namely 52.5%, knowledge including lack, namely 55%, attitude including negative, namely 60%, and information exposure including high, namely 56.2%, and parental support including lack, namely 51.2%. The results show that there was no correlation between information exposure and BSE behavior (p = 0.128), while knowledge (p = 0.022), attitudes (p = 0.001), and parental support (p = 0.003) showed a correlation with BSE behavior. It is expected that the school will cooperate with the health sector by providing material on reproductive health and prevention of non-communicable diseases, and the students are also more proactive in seeking information related to BSE


The Choquet integral (ChI) is a parametric nonlinear aggregation function defined with respect to the fuzzy measure (FM). To date, application of the ChI has sadly been restricted to problems with relatively few numbers of inputs; primarily as the FM has <inline-formula><tex-math notation="LaTeX">$2^N$</tex-math></inline-formula> variables for <inline-formula><tex-math notation="LaTeX">$N$</tex-math></inline-formula> inputs and <inline-formula> <tex-math notation="LaTeX">$N(2^{N-1}-1)$</tex-math></inline-formula> monotonicity constraints. In return, the community has turned to density-based imputation (e.g., Sugeno <inline-formula><tex-math notation="LaTeX">$\lambda$ </tex-math></inline-formula>-FM) or the number of <italic>interactions</italic> (FM variables) are restricted (e.g., <inline-formula><tex-math notation="LaTeX">$k$</tex-math></inline-formula>-additivity). Herein, we propose a new scalable data-driven way to represent and learn the ChI, making learning computationally manageable for larger <inline-formula><tex-math notation="LaTeX">$N$</tex-math></inline-formula>. First, data supported variables are identified and used in optimization. Identification of these variables also allows us recognize future ill-posed fusion scenarios; ChIs involving variable subsets not supported by data. Second, we outline an imputation function framework to address data unsupported variables. Third, we present a lossless way to compress redundant variables and associated monotonicity constraints. Finally, we outline a lossy approximation method to further compress the ChI (if/when desired). Computational complexity analysis and experiments conducted on synthetic datasets with known FMs demonstrate the effectiveness and efficiency of the proposed theory.


A clothes complex processing system is provided to more readily process without individually inputting information about the clothes by a user. A clothes complex processing system comprises a plurality of cloth managing devices(200), processing the clothes, positioned in to be adjacent, a data exchanging unit for switching the date between each cloth managing devices and a laundry storage unit(100) made of one or more among the cloth managing devices. The plurality of cloth managing devices more includes the washing machine, drier and system for safekeeping clothes.


Obesity, defined as an increase in body fat, is a growing problem in Western societies. Mean Body Mass Indices (weight [kgl/height [rn]2), a widely accepted means of assessing weight excess, have been steadily increasing in North America and in Western Europe over the last four decades. It is estimated that in the United States over 30% of the population is obese as defined by a BMI greater than 27 kg/rn2 (1).


The $68 million Productive Development Project represented 15% of the El Salvador Compact and consisted of three activities designed to transition producers to higher-profit activities, generate new investment, expand markets and sales, and create new jobs: i) Production and Business Services, (ii) Investment Support, and (iii) Financial Services. The independent interim impact evaluation on the Production and Business Services (PBS) Activity, covering the 2009-2010 phase of implementation, found varied results for the three value chains examined: impacts on employment for program participants, but no impacts on productive income in handicrafts; impacts on adoption, but no impacts on farm income in horticulture; and impacts on adoption and on farm income in dairy. Additional follow-up on the handicrafts sector showed that by the end of 2012 the increase in employment detected in the 2009-2010 phase of implementation had disappeared; no impacts were detected on net handicraft income, net annual household income, or household consumption; and negative impacts were detected on salaried income. The final data collection rounds for dairy and horticulture were cancelled due to lack of power and changes in program implementation; therefore, the final evaluation of the dairy and horticulture sectors relied upon administrative data, which indicated that PBS assistance surpassed performance targets for increased production, employment, and sales. Even so, because administrative data do not take into account what would have happened without the project, and the interim impact findings are not generalizable, it is impossible to make a definitive conclusion regarding the impact of the full PBS assistance package from 2008 to 2012. As for the Investment Support Activity, although it fell short of its original lending targets, interim results, covering the implementation period from 2007 to 2011, show that interviewed credit recipients appear to have experienced higher levels of investment, employment, production and sales than non-credit recipients. However, the comparisons of recipients and nonrecipients merely suggest the potential positive effect of the credit on these key outcomes, as there is not a valid comparison group nor a sufficient sample size to attribute differences to the activity. Final evaluation results for the Investment Support Activity, as well as for the Financial Services Activity, are forthcoming in 2016. Measuring Results of the El Salvador Productive Development Project


One hundred and eleven patients of chronic leukaemia were diagnosed over of a period of 6!/i years (January 1994 to June 2000), at Haematology Department of Shaikh Zayed Hospital, Lahore. Chronic leukaemias constituted 34% of the total 326 patients with all types of leukaemias diagnosed during the same period. Median age at the time of diagnosis for chronic leukaemias was 40 years (range 2 months to 80 years). Male to female ratio was 1.6: I. Chronic myeloid leukaemia (CML) accounted for 88 patients (79.3%), and chronic lymphocytic leukaemia for 23 patients (20.7%). Median age at presentation was 35 years (range 2 months to 75 years) for CML and 60 years (range 30-80 years) for CLL. One 44 years old male diagnosed as hairy cell leukaemia (HCL), was included in CLL patients. Age distribution showed a contrasting pattern for CML and CLL. CML was especially frequent in young and middle-age adults and showed a peak in 4th decade of life. CLL on the other hand, mainly occurred in people over 50 years, with a peak in 6th decade of life. Both the types of chronic leukaemias were more common in males. CLL however showed more pronounced male predominance.


Background: Intertrochanteric fracture is a common orthopedic injury sustained in the elderly population because of osteoporosis and trivial fall. Life-threatening systemic complications occur mainly due to immobility. Materials and Methods: We included 62 patients (40 males and 22 females) of unstable intertrochanteric fracture (AO 31 A2 and A3) attending Department of Orthopedics. They were all subjected to surgical treatment with proximal femoral locking plate (PFLP). Patients were followed up at 3rd, 6th, and 12th month for outcome variables, i.e., functional (Harris hip score, Palmer and Parker mobility score) and radiological outcomes (neck shaft angle, loss of reduction, union, and implant-related complications). Statistical analysis was done using Friedman's test after calculating the data in terms of mean and median using SPSS 20 software. Results: Mean age of our patients was 64 years; 40 were males and 22 females. Fifty patients sustained fracture due to trivial fall and 12 due to road traffic accidents. Thirty-five out of 62 patients had medical comorbidities. Twenty-six patients needed open reduction of fracture and 36 were close reduced. Twenty-two patients had severe comminution (AO A3 III type). Mean degree of loss of reduction was 5° in 6th month and 4° in 12th month. Union was achieved in 48 out of 50 patients at 12th month. Most of the patients achieved fair-to-good functional outcome scores at 12th month of follow-up. We noticed difficulties in fracture reduction as well as complications related to implant. Conclusion: PFLP is an effective implant in comminuted intertrochanteric fractures with broken lateral wall. Complications can be minimized by following the principles of locking plate meticulously.


In view of the possible finding of several tens percent of inert gas in the atmosphere of Mars by an instrument on the descent module of the USSR's Mars 6 spacecraft, the likelihood of the correctness of this result was examined. The basis for the well-known fact that the most likely candidate is radiogenic argon is described. It is shown that, for the two important methods of investigating the atmosphere, earth-based CO2 is infrared absorption spectroscopy and S-band occultation, within the estimated 1 standard deviation uncertainties of these methods about 20% argon can be accommodated. Within the estimated 3 standard deviation uncertainties, more than 35% is possible. It is also stated that even with 35% argon the maximum value of heat transfer rate on the Viking 75 entry vehicle does not exceed the design value.


Objectives . This study investigates the impact of corporate governance on the relationship between intangible assets and firm performance. The difference between internally and externally generated intangibles, ie trademarks, is taken into account. Methodology . A regression analysis is employed on 86 listed manufacturing companies across Europe, namely, Italy, Germany, France, Spain and the UK. Findings . We find that externally acquired trademarks per se do not affect firm performance. Family governance has a negative moderating impact on this relationship: too much family can jeopardize the positive effect of externally acquired trademarks on firm growth. Research limits . Our analysis is based on listed firms, which limits analysis to relatively larger firms. Smaller firms might follow different logics and are thus an interesting target for future research. Moreover, the analysis considers only brands which were codified and capitalized through trademarks reported in accounting statements: it excludes the (significant) informal and tacit side of reputation and recognition. Notwithstanding this limit, our approach allows to develop a quantitative analysis based on objective data. Practical implications . From a managerial point of view, the better understanding of the effects of trademark acquisition under different forms of governance enables the evaluation and optimization of trademark-related investments. Originality of the study . We bridge the open innovation stream of research with the family business perspective and add an additional hitherto understudied type of intangibles, ie trademark, to the respective areas of research.


1. Stevens A., Measham F. The 'drug policy ratchet': why do sanctions for new psychoactive drugs typically only go up? Addiction 2014; 109: 1226–32. 2. MacCoun R. J. The implicit rules of evidence-based drug policy, updated. Addiction 2010; 105: 1335–6. 3. MacCoun R. J., Reuter P. The implicit rules of evidence-based drug policy: a US perspective. Int J Drug Policy 2008; 19: 231–2. 4. Ross H. L. The neutralization of severe penalties: some traffic law studies. Law Soc Rev 1976; 10: 403–13. 5. U.S. Pharmacist. Drug rescheduling and controlled substances. Available at: http://www.uspharmacist.com/ continuing_education/ceviewtest/lessonid/109441/ (accessed 31 March 2014) (Archived at http://www.webcitation .org/6QIwWwx53 on 13 June 2014). 6. Drug Enforcement Administration. Rescheduling of the Food and Drug Administration Approved Product Containing Synthetic Dronabinol [(-)-D9-(trans)-Tetrahydrocannabinol] in Sesame Oil and Encapsulated in Soft Gelatin Capsules From Schedule II to Schedule III. Federal Register: 2 July 1999 (volume 64, number 127, pp. 35928–35930) from the Federal Register Online via GPO access (wais.access.gpo.gov) (DOCID:fr02jy99-3). 7. Caulkins J. P., Rydell C. P., Schwabe W., Chiesa J. Mandatory Minimum Drug Sentences: Throwing Away the Key Or the Taxpayers' Money? Santa Monica, CA: RAND; 1997. 8. MacCoun R. J., Pacula R. L., Reuter P., Chriqui J., Harris K. Do citizens know whether they live in a decriminalization state? State marijuana laws and perceptions. Rev Law Econ 2009; 5: 347–71. 9. Humphries K. U.S. marijuana possession enforcement intensity is down over 40%. Available at: http://www.samefacts .com/2014/01/drug-policy/u-s-marijuana-possession -enforcement-intensity-is-down-over-40 (accessed 31 March 2014) (Archived at http://www.webcitation.org/6QIxMvzSv on 13 June 2014). WIDENING THE DEBATE ON THE DRUG POLICY RATCHET: RESPONSE TO COMMENTARIES


The use of metaphors as the main marketing strategy in psychotropic drug advertising in journals and the quality of information provided in these advertisements has been criticised. We investigated marketing strategies and information provision in advertisements appearing in three different psychiatric journals. The majority of advertisements in two of the journals used metaphors as their main marketing strategy. The level of prescribing information varied between journals. Our findings suggest that improvements are needed in psychotropic drug advertising in journals.


Research question: UK government policy stresses the positive role that sport has on social outcomes and in the formation of social capital. However, while recognising the presence of corruption in sport, policy documentation barely considers the impact that corruption might have on social capital. This raises the following question, if sport can help build social capital, then does corruption in sport corrode it? Research methods: To answer this question, we drew on an experimental study design and the perceptions of 678 UK residents. Results and fi ndings: The results indicate that being confronted with a sport corruption case corrodes people ' s trust in sport organisations, as well as their trust in their neighbourhood, though not other elements of social capital, such as personal relationships and civic engagement. However, the more people engage with sport, the less their trust is a ff ected. Implications: The corrosion of trust indicates that corruption in sport can damage social capital. However, given that this erosion is ameliorated through a greater engagement with sport, sports organisations should engage in early robust challenges to any lack of integrity to prevent it from becoming embedded.


The chemical structure changes of three polyaorylonitrile fibres used for making carbon fibres were measured continuously during low temperature (350°C) pyrolysis in air atmosphere by the in-situ Fourier transform infrared speotroscopio method. From the information of the qualitative and quantitative spectra, it was obtained that the dehyrogenation and oxidation reactions proceeded mainly after the cyclization reaction for the British fibre, the dehyrogenation reaction occurred mainly after cyclization and oxidation reactions for the Jilin fibre, but the cyclization and dehyrogenation reactions occurred mainly before the oxidation reaction for the Lanzhou fibre. It was shown that the maximum length of cycloforming sequence for the British fibre was obtained at 260°C, for the Lanzhou fibre at 300°C, and for the Jilin fibre at 320°C. The length of cycloforming sequence of the Lanzhou fibre was the shortest. Wherefore, the results are valuable, and it may be expected that high performance PAN-carbon fibres can be obtained by improving the operation conditions of carbonization.


The pathogen causing blight and severe devastation of large cardamom in Sikkim and Darjeeling Hills was isolated and identified as Colletotrichum gloeosporioides (Penz.) Sacc. {perfect state Glomerella cingulata (Stoneman) Spauld. & Schrenk}. We propose the name, Colletotrichum blight for the disease.


The current innovation policy agenda of the government of the Russian Federation and its constituent entities is largely determined by the need for the development of end-to-end digital technologies, as it is required for the formation of competitive innovative economy with a high level of the added value. The article explores the expert assessment of the market value, which correspond to the key digital technologies, as well as underlines the crucial importance of these markets for increasing the overall investment economic activity. The article also provides a description of foreign experience of the  developed and developing countries in support the realization of projects in the sphere of end-to-end digital technologies. The scientific novelty lies in the offered model of current cooperation of the major stakeholders in the development of end-to-end digital technologies in the context of increasing their capital coefficient. The acquired results prove the high level of investment attractiveness of digital technologies, their importance for the overall economic development, as well as demonstrate the interrelation and interdependence of the stakeholders of digital economy. The presented materials can be valuable for the experts and researchers engaged in the development of digital technologies, as well as for the representatives of executive authorities dealing with the attraction of investment into the project of digital economy projects on the regional and federal levels.


Objective To discuss the treatment of liver injury involving major hepatic vein or inferior vena cava.Methods Retrospective analysis was conducted in 10 cases of traumatic liver rupture(Ⅴ level),who were admitted into our hospital from Apr.2010 and Nov.2011.There were 8 males and 2 females;age ranged from 19-46 years(mean 32 years).The injury mechanisms included road traffic injury in 6 cases,heavy weight falling injury in 1 case,horse treading injury in 1 case,stab injury in 2 cases.All these cases had severe hepatic rupture of V grade.Patients who had vascular injury included 9 cases of rupture of the inferior vena cava,4 cases of right hepatic vein rupture,1 case of left hepatic vein,1 case of main portal vein;ten cases were found right or bilateral rib fractures;nine cases were found pulmonary contusion;shock symptoms were observed in all these patients on admission.Anti-shock treatment and emergency operation were simultaneously performed in 10 cases.Results Eight cases were cured and 2 cases died.There were 2 cases of total hepatic vascular oxclusion of the inferior vena cava rupture combined with repair of liver rupture,1 case of inferior vena repair combined with partial occlusion of suprahepatic vena cava,3 cases of repair of right hepatic vein rupture,5 cases of repair rupture of post-hepatic inferior vena cava,6 cases of irregular right hepatic resection.Conclusion During the severe traumatic liver rupture(Ⅴ grade) treatment process,doctors should have active multi-disciplinary cooperation,shorten preoperative preparation time,fully liberate the liver,reasonably block hepatic blood flow,well deal with the injury in cross-section of liver and large vessels so as to improve the treatment success rate of severe liver rupture.


Optimization requires the quantities of interest that define objective functions and constraints to be evaluated a large number of times. In aerospace engineering, these quantities of interest can be expensive to compute (e.g., numerically solving a set of partial differential equations), leading to a challenging optimization problem. Bayesian optimization (BO) is a class of algorithms for the global optimization of expensive-to-evaluate functions. BO leverages all past evaluations available to construct a surrogate model. This surrogate model is then used to select the next design to evaluate. This paper reviews two recent advances in BO that tackle the challenges of optimizing expensive functions and thus can enrich the optimization toolbox of the aerospace engineer. The first method addresses optimization problems subject to inequality constraints where a finite budget of evaluations is available, a common situation when dealing with expensive models (e.g., a limited time to conduct the optimization study or limited access to a supercomputer). This challenge is addressed via a lookahead BO algorithm that plans the sequence of designs to evaluate in order to maximize the improvement achieved, not only at the next iteration, but once the total budget is consumed. The second method demonstrates how sensitivity information, such as gradients computed with adjoint methods, can be incorporated into a BO algorithm. This algorithm exploits sensitivity information in two ways: first, to enhance the surrogate model, and second, to improve the selection of the next design to evaluate by accounting for future gradient evaluations. The benefits of the two methods are demonstrated on aerospace examples.


This paper proposes strict periodic stationarity and periodic ergodicity conditions for a finite mixture integer-valued GARCH model with $ S $-periodic time-varying parameters that depend on the state of an independent and periodically distributed regime sequence. In this model, the past conditional mean values depend on the past of the regime variable in the same order, so the model is characterized by path-regime dependence. We also propose sufficient conditions for periodic stationarity when the conditional means are nonlinear of past observations. The results are applied to various discrete conditional distributions.


ZnO films were fabricated by Sol-Gel method on(001)Si substrates.The influence of annealing temperature on structure and optical properties of ZnO films was investigated.Annealing could improve crystallization and optical properties of ZnO films evidently.With the annealing temperature increasing,the grain size became larger and ultraviolet emission was observed at room temperature.While annealing temperature was higher,PL peak was stronger and had a little red shift.


la las y ideología liberal siglo XIX y siglo XX. abStract This article examines the pedagogical, social, and political dimensions of teaching psychology of religion at theological liberal protestant institutions of higher education in the United States of America, during the period of 1899 to 1927. The theoretical constructs used to analyze data are based on histori-cal-critical and epistemological analysis of primary and secondary historical sources from a Marxian, neo-Marxist, the history of mentalities or culture, and critical pedagogy perspectives, as well as social and ideological reproduction theories. The outcomes show the connections between teaching psychol-héC ogy of religion, religious education, functional psychology theory, and liberal capitalism ideology during the historical period under study.


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Modified single-zone model of radiation recuperator with microfinned surface were elaborated. In this model the researches of heat transfer and hydraulic resistance microfinned elements were applied. To calculate the recuperator wall temperature weight mean temperature was used. By elaborated model radiation recuperator with microfinned surface to glass furnace were calculated. Single-zone model makes possible the project of small overall dimensions recuperators to industrial furnaces.


Application of data mining methods is well suited for problems of effort estimation in the field of software engineering. During development process, data mining can provide software engineers with valuable inputs that support decision makings. This way it is possible to overcome the problems caused by erroneous estimates made by the experts. Use of in-house data sources is encouraged because predictive models built on top of them typically provide better estimates compared to the models generated by using data from other sources. Model predictions can either confirm experts statements or propose an alternative solution. This way software development process can become more efficient. In this empirical investigation data from five different software projects originating from the same environment were used to conduct a formal experiment. The experiment uses cross-project estimation in which data sets from other projects are used to build predictive models for the project being estimated. Predictive models implement advanced learners that in general provided more accurate predictions, thus reducing the estimation error. The evaluation of results obtained during data mining process uses established criteria. The organization of the research carried out, distinctive model and structuring of the data together with obtained results encourage the application of similar models in practice.


: There is a great demand of energy in the present world. Increased energy demand and the concern about the environmental friendly technology, renewable biofuels are a better alternative source to petroleum products. In the present study linseed oil B30(30% Linseed oil and 70% Diesel) was used as an alternative fuel for diesel engine fuel to investigate the performance characteristics of Diesel Engine with linseed oil blended diesel fuel and the results were compared with the baseline data of pure diesel. The tests were performed at compression ratio of 18CR at pressures 240bar, 220bar and Crank angle at 23° Bottom Dead Center. The results showed that the Brake power was more for B30 blend compared to diesel, it also showed that the brake thermal efficiency was found higher for diesel when compared to B30 blend at lower load conditions but brake thermal efficiency for blended fuels is higher as load increases and the Brake Specific fuel consumption was higher for the B30 blend. Linseed oil is non edible and self-lubricating oil, so it can be used as an alternative for diesel engines and for small and medium energy needs.


6-Demethoxyaustrocortirubin (6) is synthesized via the epoxide (21) which is available in 73% yield over four steps from naphthazarin (10). Hydrolysis of the epoxide (21) yields the diol (25) which on hydrogenolysis affords 6-demethoxy-1-deoxyaustrocortirubin (7). Stereoselective benzylic hydroxylation of (7) gives (6). Cleavage of the epoxide (21) with sodium acetate in acetic acid affords a mixture of the esters (22)-(24), while methanolysis yields the isomeric ethers (29) and (30). Hydrogenolysis of (22), (23) and (29) gives high yields of (7). Potentially more direct routes to the alcohol (7) involving oxymercuration, epoxidation and bromohydrin formation from the alkene (8) are not viable.


The objective of the research investigation was to design and evaluate the oral once a day matrix tablets of valsartan by using various natural matrix former gums such as separately. Initially natural gums are extracted and purified and their extracts are evaluated for their proximate phyto-chemical studies. Tablets were prepared by wet granulation method. The prepared tablets were further evaluated for physical parameters, In-vitro dissolution, and drug-excipients interactions are also carried out. The FT-IR studies revealed that there was no chemical interaction between drug and excipients. Among all prepared formulations, formulation F-8 exhibited precise controlled release of drug over a prolonged period of 24 hrs. The in- vitro dissolution data obtained for various formulations were fitted into zero order, first order, Higuchi's and Korsymeyer - Peppas kinetic models. The optimized formulation displayed zero order release kinetics and Korsmeyer and Peppas equation give release pattern with values of (n = 0.9094) indicating non-fickian (or) Anomalous types of diffusion takes place through matrix of Gum Kondagogu. The optimized formulations F-8 was subjected to stability studies for three months at  40 0 C/75%RH as per ICH guidelines and result does not shows any change in physical parameters and in-vitro release studies.


Timelines are as important for presenting temporal data as node-link diagrams are relevant for displaying graphs and relations in general. Yet, both are rarely combined. We present Time Shadows to precisely indicate a node's place in time, revealing associated temporal data and relations. We also introduce Time Beads. Created as a focus and context interaction technique for time-based graphs, Time Beads allow to continuously or discretely change the level of detail and to set multiple arbitrary focus regions if needed. We implemented both techniques in a prototype and conducted an initial user study.