The observation carried out at Xiuwen county,Central Guizhou from June,2001 to July,2003 showed that the surface runoff on yellow soil slopes coincides with the rainfall reception and it takes a considerable proportion,which leads to an inadequate utilization of precipitation and the utilization ratio decreases with the gradient goes up.The formula for surface runoff with rainfall could be simulated as Rs=-a+bP-cP2+dP3 and that for utilization of precipitation as Pe=a+bP+cP2-dP2.The cropping pattern contributes to the interaction to the utilization of precipitation with gradient.


Shortcomings of experimental techniques are usually assumed to diminish nonclassical properties of quantum systems. Here it is demonstrated that this standard assumption is not true in general. It is theoretically shown that the inability to resolve different photon numbers with photodetection may pseudoincrease a measured Bell parameter. Under proper conditions one even pseudoviolates the quantum Cirel'son bound of the Bell parameter, and the corresponding density operator fails to be positive semidefinite. This paradox can be resolved by appropriate squash models.


The Kentucky Income Reinvestment Program (KIRP) is a statewide reinvestment of income generated by the Ryan White HIV/AIDS Program (RWHAP) Kentucky AIDS Drug Assistance Program, which provides comprehensive early intervention services targeting those at the highest risk for HIV infection. The objective of this study was to compare the HIV screening rates in persons who inject drugs (PWID) at Syringe Service Programs (SSP) supported by KIRP versus SSPs not supported by KIRP in Kentucky

 A cross-sectional study was conducted on 54 SSPs. We compared the HIV screening rates in the first quarter of 2020, 2021, and 2022. Fisher's exact test compared the HIV screening rates between the KIRP supported SSPs (KSSP) versus Non-KIRP supported SSPs (NKSSP). Study data were collected and managed using REDCap electronic data capture tools hosted at Kentucky Department for Public Health. The statistical analyses were performed with Stata 17 (College Station, TX: Stata Corp LLC).

 The analysis included data of 21,072 PWID who attended the SSPs utilizing the REDCap electronic data capture tool during the study timeframe. In the first quarter of 2022, a total of 1,607/4795 (33.5%) PWID were screened for HIV at KSSP vs 12/482 (2.5%) at NKSSP (p=< 0.001). The difference in the screening rates has increased over the years since the KIRP began in 2019 (Figure 1).

 The HIV screening rate in PWID has increased significantly in the SSPs supported by KIRP through RWHAP program income early intervention funds. This increase has occurred mainly in rural counties where people who inject drugs remain a significant population at risk for new HIV infections.

 All Authors: No reported disclosures.


Methods of controlling seepage and excessive hydrostatic pressures beneath dams and levees founded on deep strata of pervious sands are presented in this paper. The principles involved in the different methods of under-seepage control are also considered. Although the design of seepage control measures is not an exact science, formulas and criteria for preparing a rational design of such are given. These are based on known seepage laws, laboratory tests, and field observations.


In short study below we report effects of ambient air
atmospheric pressure plasma treatment of polycarbonate surface.
Atmospheric plasma treatment was done by two different plasma
sources. First was special type of dielectric barrier discharge
called Diffuse Coplanar Surface Barrier Discharge (DCSBD).
Second one was glide arc like plasma APC 500. We report
significant changes in surface free energy, water contact angle
and hysteresis calculated from dynamic contact angle
(advancing, receding).


A 73-year-old woman presented to a clinic with right upper abdominal pain. Abdominal ultrasonogra-phy indicated the presence of cholecystolithiasis, and the patient was referred to our hospital for surgery. During laparoscopic cholecystectomy, a nodular lesion, 6 × 3 mm in size, was noted on the serosal surface of the body of the gallbladder. No communication was noted between the liver and the nodular lesion; however, the color of the nodular lesion was identical to that of the main liver. Patho-logically, the surface of the nodular lesion was found to be covered with a smooth fibrous capsule, and the Glisson's sheath and central vein were seen, thus illustrating the normal structure of a liver lobule. The lesion was therefore diagnosed as ectopic liver. Ectopic liver is a rare anomaly of the liver. Most patients with ectopic liver are asymptomatic, and is usually detected incidentally on the serosal surface of the gallbladder during surgery or laparoscopy.


Several investigations have been carried out on nodulation mainly in legumes of agronomic importance. However, several native species still remain completely unexplored. The study of nodulating native legumes will provide key knowledge for the conservation and management of species with adaptation to harsh environmental conditions. Therefore, the purposes of this review are: a) To describe the infection mechanisms of rhizobia associated with Fabaceae known until now, b) To analyze the most important research works reported on nodule morphology and structure, c) synthesize the most significant advances on nodulation in the three sub-families of Fabaceae. It is concluded that to date three infection mechanisms by rhizobia are known: I) The infection threads in the radical hairs that occur in genera such as Acacia, Mimosa and Prosopis belonging to the Mimosoideae sub-family; as well as in Lotus, Medicago and Robinia, belonging to the Papilionoideae sub-family, II) the crack entry mechanism that occurs in legumes of the Dalbergieae tribe, and III) direct infection through the epidermis root characteristic of the Genisteae tribe. As a result of bacterial infection different morphological types of nodules are formed. Regarding the structure, they are constituted by three types of tissues that have a specific function in the nitrogen fixation. In species subjected to unfavorable conditions, changes in structure are observed, such as the formation of periderm and lenticels. Currently, the sub-family Papilionoideae is the most studied as far as nodulation is concerned, particularly the genera belonging to the tribus Dalbergieae, Desmodieae, Genisteae, Loteae, Millettieae, Phaseoleae, Sophoreae and Trifolieae.


A novel Combined Field Current and Charge Integral Equation is presented for perfect electric conductors. The equation is non-resonant and has good properties in low and high frequency regime. Analytical proofs and numerical evidences are provided. The numerical examples are solved by using the multilevel fast multipole method.


A method is described for characterization of sulfur compounds in unaged and aged whisky. The method is based on full evaporation dynamic headspace (FEDHS) of 100 L of whisky samples followed by selectable one-dimensional (1D) or two-dimensional (2D) retention-time-locked (RTL) gas chromatography (GC)–mass spectrometry (MS) with simultaneous element-specific detection using a sulfur chemiluminescence detector (SCD) and a nitrogen chemiluminescence detector (NCD). Sequential heart-cuts of the 16 sulfur fractions were used to identify each individual sulfur compound in the unaged whisky. Twenty sulfur compounds were positively identified by a MS library search, linear retention indices (LRI), and formula identification using MS calibration software. Additionally eight formulas were also identified for unknown sulfur compounds. Simultaneous heart-cuts of the 16 sulfur fractions 2 Author's Personal Copy FEDHS) electable 1D/2D RTL GC–MS lement-specific detection rincipal component analysis (PCA) were used to produce the D RTL GC-SCD chromatograms for principal component analysis. PCA of the 2D RTL GC-SCD data clearly demonstrated the difference between unaged and aged whisky, as well as two different whisky samples. Fourteen sulfur compounds could be characterized as key sulfur compounds responsible for the changes in the aging step and/or the difference between two kinds of whisky samples. The determined values of the key sulfur compounds were in the range of 0.3–210 ng mL−1 (RSD: 0.37–12%, n = 3).


A diversity of different Human Reliability Analysis (HRA) methods are applied in Probabilistic Risk Assessments (PRAs). The Halden Reactor Project has, together with its member organizations, initiated a project to address a desire to test these methods against empirical evidence. In the initial phase of the project, specific accident scenarios have been chosen and human failure events (HFEs) have been identified. As part of these first trials, we are learning about some of the constraints, issues, and characteristics of the scenario designs that have to be dealt with. For instance, scenarios should be PRA/HRA relevant, sufficiently challenging to be useful tests of the HRA methods and yet be plausible, and also be feasible in a simulator setting. We are also learning about issues on how to define the HFEs of interest to ensure usefulness of the results to PRA/HRA. For instance, HFEs must be measurable and defined so that success of the action and failure of the action are clearly distinguishable. Process-based success criteria can for example reflect on several HFEs, and to define success criteria for individual HFEs other measures might be needed. This paper will discuss lessons learned about scenario design and the defining of HFEs to be able to progress toward testing HRA methods using simulations of accident scenarios.


A liquid‐like ordered polystyrene latex suspension of particle diameter σ=109 nm and concentration ρ=1.62×1018 particles/m3 was investigated via its light scattering structure factor S(Q) in the temperature range from 21 to 70 °C. Contrary to previous investigations we did not find a rapid collapse of the liquid‐like structure at higher temperature. Comparison of the experimental S(Q) with structure factors derived in the rescaled mean spherical approximation (RMSA) of Hansen and Hayter indicates that the experimental S(Q) at 70 °C are slightly less structured than predicted by the model. With the assumption of an extra ionic strength at 70 °C of I=1.0×10−6 mol/l due to impurities the experimental S(Q) can well be rationalized in terms of the RMSA liquid model.


This study presents the psychometric proprieties of the Italian version of the Social Dominance Orientation7 (SDO7) Scale, originally developed by Ho et al. (2015). We recruited a convenience sample (N = 497) to answer an online self-report questionnaire, including the SDO7 Scale and other relevant convergent and divergent measures. The confirmatory factor analysis revealed that SDO7 presents a satisfactory fit to the data, both as a two-correlated factor structure and as a one-dimensional measure. The two-correlated factor structure is confirmed as composed by two subdimensions as in the original version: the SDO-Dominance (SDO-D) and the SDO-Anti-Egalitarianism (SDO-E). Since the total SDO7 score measures people's support for asymmetrical group relationships, the SDO-D is concerned with people's support for dominant-submissive forms of intergroup relationships whereas the SDO-E refers to the desire to support intergroup inequalities. The scale and subscales also present satisfactory indexes of reliability as well as convergent and divergent validity.


DFT/TDDFT calculations were carried out to investigate the electronic structures, absorption and phosphorescence properties of a series of heteroleptic Ir(III) complexes consisting of two N-heterocyclic carbene ligands and a conjugated bicyclic N,N′-heteroaromatic (NˆN) ligand. On the basis of the results reported herein, we attempt to explain the experimental observations according to which complex (mpmi)2Ir(pybi) (1) [Hmpmi = 1-(4-tolyl)-3-methyl-imidazole; Hpybi = 2-(pyridin-2-yl)-1H-benzo[d]imidazole] emits green light with an extremely high-quantum phosphorescence efficiency (Φ PL ) of 79.3%, while a relatively lower Φ PL (only 11%) was measured for (fpmi)2Ir(tfpypz) (2) [fpmi = 1-(4-fluorophenyl)-3-methylimdazolin-2-ylidene-C, C2′; tfpypz = 2-(3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridinato] emitting blue light by tuning the NˆN ligands. Besides, we also designed (fpmi)2Ir(pyN3) (3) [pyN3H = 2-(5-(trifluoromethyl)-2H-1,2,4-triazol-3-yl)pyridine] and (fpmi)2Ir(pyN4) (4) [pyN4H = 2-(1H-tetrazol-5-yl)pyridine] to explore the influence of electron-withdrawing substituents on NˆN ligands on the electronic and optical properties of these Ir(III) complexes. The results revealed that electron-withdrawing substituents can stabilise both HOMOs and LUMOs and induce HOMO–LUMO energy gap change. Moreover, the emission properties can be significantly tuned by introducing different NˆN ligands. While new insights were gained on structural and electronic properties, the extremely high Φ PL of 1 was found to be not inherent to spin-orbital coupling effects, but determined by its large transition dipole moment (μS 1) upon S 0–S 1 transition compared with that of 2. On the basis of these results, the designed complexes 3 and 4 are considered to be the promising candidates for blue-emitting phosphorescence materials with higher Φ PL than the complex 2.


Often focusing on permission to act or not to act, debates about sexual consent are multifaceted and enduring. The pervasive presence of digital technology in young people's lives has added new complexities to 'sextual' consent. Drawing on qualitative small friendship group interview data with school-aged young people in Aotearoa New Zealand, this article provides insights into their understandings of consent surrounding the creation and sharing of intimate images. Through navigating the nuances of sextual consent, young people are forming their own informal norms and expectations. These informal norms are strengthened by competitive masculinity which disadvantages young women at all stages of the process, resulting in gendered harms and victim blaming. Many young people expressed views that unsafe sexting, in terms of pressure, coercion to produce the image, the image being shared without consent and the resulting fall out, could be avoided with an enhanced programme of digital literacy. While digital literacy has merit, it should not be at the expense of conversations around gender, power and culture, desire, victimisation, or how young people from different socio-cultural backgrounds navigate these relations.


Objectives: To investigate the influence of platelet rich plasma(PRP) on proliferation and differentiation of marrow stromal cells(MSCs) in coral scaffold in vitro.Methods: A suspension of 5×106 MSCs in 50μl medium were dissolved in 50μl of PRP.The mixture of MSCs and PRP was spread on a coral disc with diameter of 8 mm and thickness of 2 mm,so coral/MSCs/PRP composite was obtained.A suspension of MSCs in 50μl medium was spread on a coral disc to obtain coral/MSCs composite.50μl of PRP was added on a coral disc to obtain coral/PRP composite.Coral/MSCs/PRP composite was cultured in a humidified incubator for 8 and 14 days.The medium was changed every other day.Coral/MSCs composite and coral/PRP composite were used as control.Then three types of composites were processed to evaluate ALP activity,osteocalcin and proliferation of MSCs in the constructs.The composites were also evaluated cell adhesion,growth and proliferation of MSCs on coral scaffold by scanning electron microscope.Results: The ALP activity and content of osteocalcin were significantly higher in the samples of coral/MSCs/PRP group compared to that of coral/MSC group at 8 and 14 days in vitro(P0.05).A comparison of the results of MSCs proliferation showed that cell growth increases as a function of PRP in coral scaffolds.Scanning electron micrographs showed more cells adhered to the scaffolds of coral/MSCs/PRP than that of coral/MSCs,and some asteroid MSCs were bound by the fibrin network.Conclusion: These in vitro study results suggest that MSCs may be encouraged to proliferate and osteogenically differentiate by PRP in the coral scaffold,leading to increased osteogenesis in vitro.


Abstract Probable confidence intervals for Petersen population estimates play an important part in decisions concerning the number of animals that must be marked and the size of the catch from which recaptures must be obtained. Requirements for an acceptable confidence interval may be so difficult to satisfy as to make a study impractical, even though the confidence interval itself is based only upon magnitude of numbers and not upon their accuracy. Graphs of the changes in confidence intervals from large to small as the magnitudes of marks applied, marks recovered, and catch change from small to large are presented to give perspective for the planning and development of Petersen population estimates. Confidence intervals were estimated by use of published formulas, tables, and graphs.


Research on the health of older adults in Latin America and the Caribbeanhas been neglected in epidemiology and public health. This is of grave con-cern since dramatic changes in fertility and mortality rates in recent decadesensure a rapid aging of the population in the Western Hemisphere. Persons60 and older in Latin America and the Caribbean now make up 8% of the totalpopulation; by the middle of this century that figure will grow to 22%. Inabsolute numbers, the population of older persons will total over 180 millionby 2050. In the coming decades we expect to find poorer health status andgreater disability in the cohorts of persons who survived childhood and adultdiseases. That higher survivial rate is due more to public health interventionsand less to an improvement in their socioeconomic status. Therefore, policy-makers in Latin America and the Caribbean need to understand the correla-tions among different gradients of poverty, access to health care, social net-works, and health in old age. The epidemiology of aging and longevity provides a framework forunderstanding both the risk factors associated with old age and the atypicalmanifestations of infectious diseases in persons with diminished immunity.Elders in Latin America and the Caribbean will often suffer from a complexmix of infectious and noncommunicable diseases, and infectious diseaseswill continue to be an important cause of adult mortality. Thus, we needmore information on the complex interaction of diseases, frailty, socioeco-nomics, and social networks in old age. We still have great gaps in ourknowledge of aging in the Region of the Americas; it is not surprising thatolder persons are underrepresented as a target population in the publichealth literature. The essential functions of public health, including monitoring, eval-uation, and analysis of the health status of older persons, require the devel-opment and use of multidisciplinary research designs (1), new assessmentprotocols, and adequate survey instruments in order to capture the specificcharacteristics of older adults. With the support of the National Institute onAging of the United States of America, the Pan American HealthOrganization is collaborating with researchers in the Americas to developmore efficient data collection instruments and thus promote demographicand epidemiological studies of older persons. Ideally, in the future, infor-mation systems and researchers in different countries will collect compara-ble data on health and aging and therefore produce important insights intothe roles that culture, socioeconomic status, and different institutionalapproaches play in the health of older persons.While aging research in the developed countries has produced a vastscientific literature, much more dialogue among researchers in all the coun-tries of the Americas is needed in order to develop a better understanding ofthe health and well-being of older adults. In this issue of the


Abstract Failure of the duplex stainless steel piping system in oil and gas industry can have disastrous effects. In this study, a novel method of failure analysis of flow-induced vibration problem of in-serviced duplex stainless steel piping system is proposed. The proposed non-destructive technique is able to determine a suitable operating condition for continuous operation without failure. The technique relies on the combined operation of operational modal analysis, operating deflection shape analysis and linear elastic finite element analysis. The effect of different operating conditions for two distinct valve opening cases (i.e. fully opened and partially opened) on the dynamic stress is examined, and they are utilised for forecasting purpose in failure analysis. The result shows that maximum operating conditions are 360 and 400 mmscfd for fully opened and partially opened flow control valves, respectively. Beyond this limit, the piping system most likely will fail.


Rodin in the light of Rembrandt or "Of what is Rembrandt the name?". Rodin frequently makes spoken references to Rembrandt, as do commentators of Rodin's work. Objectively, Rodin looks at Rembrandt, sometimes copies him and seeks to unravel certain of the Dutch master's secrets. But these references and the identification with the painter of the "Syndics" are encompassed in a discourse whose historiographical perspectives this article seeks to decipher.


Member 1 of the Lower Cretaceous Quantou Formation is the principal section of the Shuangtuozi gas field located in the Songliao Basin.There develops the meandering river deposition system and braided river deposition system.By using the petrofacies and electrofacies switching technology,the authors divide and compare the sedimentary microfacies of Member 1 of Quantou Formation in the study area,and therefore further recognize the sedimentary microfacies,such as marginal bank,point bat,crevasse splay,channel lag,natural levee,bet lands,etc..Also,they study the planar distribution characteristics of the sedimentary microfacies so as to provide significant evidences for forecasting sandbody space distribution and 3-D reservoiring modeling.According to statistic analysis of physical property materials,and under the control of sedimentary microfacies,the marginal bank sandbody is the most benificial reservoir belt in the meandering river deposition system of the study area,and the batture sandbody is that in the braided river depositional system of the study area.


This essay seeks to explicate the ethical dimension of Schelling's project. Schelling complicates the theory/praxis distinction by arguing that these two modalities are different sides of the same movement in thinking. I attempt to establish this by first examining Schelling's early essay, Neue Dedukhon des Naturrechts, and then by turning to his celebrated Freedom essay. Although I chiefly examine an early work and then a work from his middle period, I contend that the ethical dimension governs all of Schelling's thinking. I examine closely Schelling's description of Mitwissenschaft (the conscience). I further develop my argument by contrasting Nietzsche's understanding of this notion with Heidegger's treatment of it in Being and Time. I then turn to Hannah Arendt and her discussion of"radical evil" and the "conscience" in order to deepen our appreciation of Schelling's watershed contribution.


A hydrogel-actuated microvalve that responds to changes in the concentration of glucose in an external liquid environment is described. The microvalve consists of a thin hydrogel, sandwiched between a stiff porous membrane and a flexible silicon rubber diaphragm. Swelling of the hydrogel forces the membrane to deflect therefore boss causes the valve to be opened. Simulations have been done by FEM analysis and the results show enough deflection to open the valve and let the fluid flow through the microchannel to obtain 130 microliter/min for output flow.


Counseling for medical patients and their families which focuses on the emotional adjustment to long-term hospitalization, illness and disability is relatively new to the medical setting. Only in recent years have hospitals begun to recognize their responsibility in responding to the emotional and social components of illness through structured programs geared specifically to this process of adaptation to illness. Based on the assumption that families as well as patients experience emotional stress upon hospitalization of a family member, medical counseling groups were developed at St. Mary's Hospital and Extended Care Center in an effort to more effectively and efficiently support the patient and others in his family network. This paper describes some practical measures for assuring family involvement in physical rehabilitation and discusses some possible methods of establishing such groups in a hospital setting. Case examples in the areas of stroke, cancer, diabetes, and coronary care illustrate the encouraging results of these groups.


Objectives-This survey was conducted to determine thefrequency withwhich different dataanalysis techniques are beingusedinoccupational cohortstudies. Ofparticular interest was therelative use ofexternal andinternal comparison groups, andthechoiceofmultivariable model. Methods-Occupational cohortstudies published in1990-91 were located with MedlineandIndexMedicus, andthecontentsofseveral relevant journals were systematically reviewed. Eachstudywas categorized bythemethodsofexternal or internal comparisons performed. Results-Of200 occupational cohort studies identified, 104(52%)conducted onlyexternal comparisons, 46(23%)conductedonlyinternal, and50(25%)presentedboth.Of thosethatused an external referent population, abouttwo thirds useda national standard. 40ofthe studies thatperformedinternal comparisonsfitted multivariable models,with use dividedaboutequally betweenproportional hazardsregression, Poisson regression, andlogistic regression. Discussion-Thefindingthatlogistic regression isusedquitecommonly,even thoughitdoesnot directly modeltime dependentdataofthetypefrequently encounteredin occupational cohort studies, was suprising. The reasons why investigators choosefrom among the availablestatistical and modelling techniques are likely toinclude familiarity,ease of use, restrictions in study populationcharacteristics, especially studysize, andothers. Authorsshouldbe encouraged tobemore explicit aboutthe statistical methodsusedintheanalysis of occupational cohortstudies, as wellas whetherimportantassumptions about theirdatahavebeenevaluated. (Occup Environ Med1994;51:649-655)


Information on the degree and type of branching in ten different microcrystalline waxes, their saturated and aromatic fractions has been obtained by proton nuclear magnetic resonance. The branches present in these waxes are of the long-chain type with a terminal methyl group and an average of about 1.3 branches per molecule.


This paper deals with the impact of rotor bar materials such as aluminum or copper on domestic heating circulator pumps . First, we describe the test bench used to do experiments. Secondly, we present the interest of changing rotor bar materials in pumps system drives and finally, we present experimental results.


Patients with the plasma cell malignancy multiple myeloma now benefit from treatments such as proteasome inhibitors, immunomodulatory imide drugs (IMiDs), autologous stem cell transplant, and monoclonal antibodies. However, 20% of patients still relapse or die within two years and are deemed 'high risk'. Current markers fail to identify all high-risk patients resulting in misdiagnoses, therefore additional markers for this deadly form of the disease are required.
 To better understand and identify high-risk myeloma, we analyzed the structural variant landscape of 826 myelomas from newly-diagnosed patients using whole genome sequencing as part of the CoMMpass trial (NCT01454297). High-confidence somatic structural variants were determined using DELLY and quality control metrics to exclude regions with sequencing anomalies.
 Myeloma from newly diagnosed patients had a median of 21 somatic structural variants including 7 duplications, 2 deletions, 7 inversions, and 3 translocations. The number of deletions, duplications, and translocations corresponded to poor progression-free (PFS) and overall survival (OS), with translocations being the most significant (P <6.1x10-7). The two most common translocations occurred at the IgH (41%) and MYC (23%) loci, but did not correspond with differential outcome. However, the third most commonly translocated region (10%) occurred at the IgL locus and was indicative of poor PFS and OS with hazard ratios (HR) of 1.71 and 1.81, respectively (Figure 1). IgL-translocated myeloma did not correspond with distinct clinical features such as age, stage, gender, or b2M levels; and IgL-translocated patients were treated with similar therapeutic regimens as others. Additionally, IgL-translocated myeloma did not have a distinct mutational repertoire, gene expression subtype, and did not have many unique structural genetic elements. The notable exception is that 70% of IgL-translocated myeloma co-occurred with hyperdiploidy, a marker normally associated with better prognosis. However, patients with IgL-translocated and hyperdiploid myeloma experienced poor outcome with a median PFS of 23 months compared to 42.8 months for non-t(IgL) hyperdiploid myeloma (PFS HR=2.35; OS HR=2.41). This poor outcome is partially explained by the failure of patients with IgL-translocated myeloma to benefit from IMiDs. In fact, IMiDs provided no survival benefit to patients with IgL-translocated myeloma who experienced poor outcomes commensurate with patients that did not receive IMiDs (PFS HR=1.56; OS HR=1.49). This is in contrast to patients with myeloma that harbor other translocations, such as IgH translocation, who benefited from IMiDs (PFS HR=0.83, OS HR=0.61).
 These data identify IgL translocation as an independent marker of poor prognosis regardless of translocation partner, and suggest this may be due to the failure of this myeloma subtype to benefit from IMiDs. One potential mechanistic explanation is that the IgL enhancer is one of the most robust enhancers of gene expression and is therefore uniquely resistant to therapeutic inhibition. Indeed, the IgL enhancer is bound by several transcription factors at some of the highest levels in the B cell / myeloma epigenome, including BRD4, MED1, and IKZF1. This last factor is particularly interesting as IKZF1 is the target of IMiDs, and thus high-levels of IKZF1 occupancy at the IgL enhancer may be more difficult to fully deplete therapeutically than other loci. This may explain why patients with IgL-translocated myeloma do not benefit from IMiDs whereas patients with IgH- or IgK-translocated myeloma do. Finally, the co-occurrence of myeloma with IgL-translocation and hyperdiploidy is particularly unfortunate, as hyperdiploidy is routinely tested for clinically, whereas IgL-translocations are rarely diagnosed, likely resulting in their misclassification as standard risk.
 Figure: IgL translocations portend poor prognosis. a Circos plot showing the repertoire of IgL translocations in newly diagnosed myeloma where line thickness denotes frequency (key bottom left). b Kaplan-Meier analysis of IgL translocated [t(IgL)] patients (N=81) as compared to non-t(IgL) (N=745) for progression-free (PFS; top) and overall survival (OS; bottom). P-values were calculated using a Cox proportional hazards Wald's test or permutation based P-value with 1,000 permutations based on the hazard ratio.

 Neri: Celgene: Consultancy, Honoraria; Janssen: Consultancy, Honoraria. Bahlis:Amgen: Consultancy, Honoraria, Research Funding; Celgene: Consultancy, Honoraria, Research Funding; Janssen: Consultancy, Honoraria, Research Funding. Nooka:Adaptive technologies: Consultancy, Membership on an entity's Board of Directors or advisory committees; Amgen: Consultancy, Membership on an entity's Board of Directors or advisory committees; GSK: Consultancy, Membership on an entity's Board of Directors or advisory committees; Takeda: Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Membership on an entity's Board of Directors or advisory committees; BMS: Consultancy, Membership on an entity's Board of Directors or advisory committees; Janssen pharmaceuticals: Consultancy, Membership on an entity's Board of Directors or advisory committees; Spectrum Pharmaceuticals: Consultancy, Membership on an entity's Board of Directors or advisory committees. Kaufman:Janssen: Consultancy; Roche: Consultancy; Karyopharm: Other: data monitoring committee; Abbvie: Consultancy; BMS: Consultancy. Lonial:Amgen: Research Funding. Boise:Abbvie: Consultancy; AstraZeneca: Honoraria.


We propose a learning-based approach for open driver guidance and rebalancing in ride-hailing platforms. The objective is to further enhance the wait time reduction benefit of batched matching by incorporating learning-based open driver guidance and rebalancing. By leveraging the rider demand data, the guidance solutions are computed through the integration of machine learning techniques with a two-stage stochastic programming model. To validate the performance of the proposed approach, we conduct numerical experiments using the New York taxi trip data sets. Our results show that the proposed approach outperforms the single value estimation model and the parametric model using Poisson distribution in terms of average wait time. When assuming the open drivers are randomly located before the batching time window, the proposed approach reduces more than 70% of average wait time compared to batched matching without guidance.


In this paper,a design model at different bent angles of spine in two-dimensional space is built to design more comfortable desks and chairs in campus.The best proposals to design the desks and chairs are obtained at the working and the sleeping postures,respectively.Then,the best design proposal,H = 32.79cm,S = 35.60cm is advanced by combining working posture with sleeping posture.It is approximate to the real measurements.


Mr Stone is illuminating on Inany issues, not least in his discussion of marriage. He regards aristocratic attitudes towards marriage as being essentially patriarchal, in contrast with new attitudes growing up arnong the middle classes, who allowed their children a lnuch greater freedom of choice. The aristocracy followed medieval tradition in looking on marriage as primarily a social institution, in which the wishes of the individual did not count. The future of the estate, bound up as it was with a suitable match, was the all-important criterion. On this and much else Mr Stone is a fascinating guide. If a criticism may be offered of this book, it is a basic one, concerned with Mr Stone's concept of the English aristocracy. He seems to define ' aristocrat ' in terms of a military aristocracy But can we be so certain as he is that the possession of a title indicates an ' aristocratic ' way of life and attitude of mind? Most of Mr Stone's peerage in 1558 were recently enobled for political services. They constituted, if anything, n ' noblesse de la robe ' with its own set of values. What nleaning had the values of a ~nilitary aristocracy for the titled civil servants of Elizabeth's reign? I t is unfair to say that Mr Stone is unaware of this issue, but his incidental references do not make up for an overall vagueness on the point. Significantly, his index refers to 'honours, sale o f ' but not to ' honour ' Few readers will fail to appreciate the brilliance of this book. As a piece of sustained writing, it has few contemporary counterparts in English historiography. The author acknowledges his debt to R. H. Tawney and he has repaid it a hundredfold. But perhaps the defects as well as the merits of his mentor may be discerned. There is none of Tawney's obsessive biblical imagery in Stone, but there is an elnotional quality about his writing which blurs its intellectual impact. Yet one would give a good deal for an Irish equivalent which provides liveliness and illumination in such ainple measure. H. F KEARNEY


"Mucormycosis" term is used for a group of fungal diseases caused by the order mucorales. It typically presents as sino-nasal-orbital involvement and rarely involves skin. Management of such cases is quite challenging. Reported here is a case of a young girl, who presented with right eye swelling and reduced vision and got detected with type 1 diabetes mellitus on admission with rare occurrence of cutaneous lesions while on treatment. Direct nasal endoscopy with biopsy was undertaken. KOH and histopathology report was suggestive of mucormycosis, for which the patient was administered intravenous amphotericin B and surgical debridement was carried out. With the accurate application of a multidisciplinary approach with timely investigations, imaging studies, antifungals and debridement, successful outcome in mucormycosis is well within our reach.


Objective: To investigate the influence of fast tract surgery on the immune function and inflammatory responses after Laparoscopic colorectal resections in cancer patients.Methods: 122 patients were randomized to receive traditional protocol and open surgery(groupⅠ,n=39),fast track protocols and open surgery(group Ⅱ,n=42),fast track surgery and laparoscopic surgery(group Ⅲ,n=41).CRP、IL-6、IgG、IgM、IgA、CD3+、CD4+、CD4+/CD8+were tested before operation and after operation for 3 and 7 days.Results: On the day 3,7 postoperatively,IL-6 and CRP significantly increased as compared to those preoperatively in three groups(P0.01),but the parameters in group Ⅰwere significantly higher than those in group Ⅱ and Ⅲ(P0.01),and the parameters in group Ⅱ were significantly higher than those in group Ⅲ(P0.05).On the day 3 postoperatively,IgG、IgM、IgA significantly decreased as compared with those preoperatively in three groups(P 0.05),and the parameters in group Ⅰ were significantly lower than those in group Ⅱ and Ⅲ(P0.01).On the day 7,there was no significant difference of IgG、IgM、IgA between before and after operation in groupⅡ and Ⅲ(P0.05),but the parameters in group Ⅰ were significantly lower than those preoperatively.On day 3 postoperatively,CD3+,CD4+and the ratio of CD4+/CD8+significantly decreased as compared to those preoperatively in three groups(P0.05),and the parameters in group Ⅰwere significantly lower than those in group Ⅱ and Ⅲ(P0.01).The levels of CD3+,CD4+ and the ratio of CD4+/CD8+ recovered rapidly in group Ⅱ and Ⅲ on the day 7 postoperatively(P0.05),but the parameters in group Ⅰ were significantly lower than those preoperatively.Conclusion: Fast track surgery mitigates the immunologic impairment of colorectal cancer patients after laparoscopic colorectal resection,and accelerates postoperative rehabilitation.


Uncertainty is often named among the most significant factors impeding decision making in systems with partially independent agents, both technical and social. Among such systems, multilevel systems can be distinguished as a hard case, as uncertainty problem there is combined with the problem of agent opportunism. A special class of mechanisms — the Groves mechanisms that satisfy the requirements of truthfulness in dominant strategies and efficiency — has been well studied in the literature. The article shows how, under conditions of multilevel multi-agent systems with uncertainty, the implementation of Groves mechanisms can solve the problem of systematic distortion of the agents behaviour.


Plant for the production of dispersed mineral products, with a mill, a flow classifier and a system for deposition of the dispersion air, characterized in that between the flow classifier (2) and the air separation system (7, 8, 9) an electrostatic separation chamber (3) for separating the is installed in the flow classifier triboelektrostatisch charged foreign particles.


Java program testing professionals have required effective test suites in fault detection within limited budget. To generate more effective test suites, they have evaluated test suites by mutation analysis. Therefore, researchers have been suggested more powerful mutation adequacy criterion. Also, they have studied on automatizing the process of test data generation and reducing the test suite size by prioritization to reduce the cost it takes to test programs. In this paper, we suggest an automated test suite generation approach using genetic algorithm and powerful mutation adequacy criterion. The proposed approach is implemented in the previous tool, EvoSuite. The test suite generated by our approach is up to four time more effective than test suites generated by original EvoSuite. Keywords-automated test generation; genetic algorithm; mutation analysis; d-criterion


This paper investigates the machining mechanism of titanium alloys and analyses those understandings systematically to give a solid understanding with latest developments on machining of titanium alloys. The chip formation mechanism and wear of different cutting tools have been analyzed thoroughly based on the available literature. It is found that the deformation mechanism during machining of titanium alloys is complex and it takes place through several processes. Abrasion, attrition, diffusion–dissolution, thermal crack and plastic deformation are main tool wear mechanisms.


Abstract Phosphate solubility in Andisols and Andic soils (forest and fertilized) has been studied in soil solutions at two soil:solution ratios (1:2.5 and 1:25). Forest soils approached the variscite solubility (pIAP=30.4±0.3) while fertilized soils were closer to the amosphous analog of variscite (pIAP= 29.8±0.2). In some samples, phosphorus (P) activities were consistent with simultaneous equilibrium between aluminum (Al) and iron (Fe) phosphates. The dilution ratio, DR=10(P)1:25/(P)l:25, was 10.0±0.4 for all samples. This suggests a dissolution of phosphate minerals attaining apparent saturation in 24 h. However, the high content of dissolved organic carbon and Al in aqueous extracts also pointed to the existence of soluble ternary complexes of P with Al(Fe)‐humus complexes. These results could be consistent with simultaneous control between the dissolution of variscite‐like minerals and humus‐Al(Fe)‐P associations. Nevertheless, DR seems a valuable criterion to assess soil P status, especially in fer...


In these days,the conflicts between land use and economic development in our country have become more and more serious.Hence we raise the question: how to achieve the goals of efficient use of land and persistent economic development at the same time? In order to answer this question,it is obviously necessary to analyze the relationship between these two goals.We take the data of "top hundred counties" and make multiple and variable analysis of choosing indexes about the land use and economic development.As a result,we find out some strong positive correlation exists between these two items.Therefore,controlling of land amount is one of the effective means of macro-control.Besides,the adjustment of land policy and perfection of land institution,as well as progress of market management have become the imminent requires for the economic development in the new era.


One factor which influences the success of poverty alleviation program is to determine where the poverty is concentrated. There are 15 provinces that have a value index of poverty depth (P1) higher than the value of P1 Indonesia. This study will describe the characteristics of poverty in 15 provinces; identify key factors affecting poverty at the macro level; and the relationship between each of the major factors in P1. Based on factor analysis obtained there are three main factors that characterize the 15 poor provinces, which are employment, education, and residence. Logistic regression analysis showed the relationship between employment factors and education with the negative P1. Both employment and educational factors have a significant effect on P1. Meanwhile, factor of residence was positively related to P1 but the effect is not significant.


The Real-Time Multiprocessor Simulator (RTMPS) is a multiple microcomputer system used to investigate the application of parallel-processing concepts to real-time simulation. This users manual describes the set-up and installation considerations for the RTMPS hardware. Any modifications or further improvements to the RTMPS hardware will be documented in an addendum to this manual.


We present novel optical circuits consisting of low-loss photonic crystal butt-jointable to/from fibers (Fiber-to-fiber loss of 4.6 dB over a waveguide 3 mm long). To show its versatility, we demonstrate an in-line resonator with Q = 270


Infective endocarditis (IE) commonly complicates bicuspid aortic valve. We report an uncommon case of bicuspid aortic valve (BAV) IE with aortic root abscess (ARA), presenting initially with abdominal pain due to splenic infarcts, delaying prompt diagnosis. A 38-year-old gentleman presented with fever and abdominal pain. He was treated for intra-abdominal sepsis, was started on intravenous antibiotics and had a computed tomography scan of the abdomen that revealed a large splenic infarct. The patient deteriorated, prompting further investigations, including echocardiography due to findings of a new murmur, signs of embolisation and blood cultures revealing Staphylococcus aureus. This revealed an otherwise unknown BAV with aortic valve vegetation and ARA. IE and ARA commonly affect patients with bicuspid aortic valve, and our case highlights the importance of systemic review, as IE often manifest clinically in various forms.


A relatively new minimally invasive cardiological procedure, called the MitraClip™, does not require sternotomy and may have a number of advantages compared with open mitral valve surgery, but its acute impact on the pulmonary circulation and right ventricular function during general anaesthesia is unclear. We prospectively assessed the effects of the MitraClip procedure in 81 patients with or without pulmonary hypertension (defined as mean pulmonary artery pressure > 25 mmHg), who were anaesthetised using fentanyl (5 μg.kg−1), etomidate (0.2–0.3 mg.kg−1), rocuronium (0.5–0.6 mg.kg−1) and isoflurane. Placement of the MitraClip led to a 60% increase in mean (SD) right ventricular stroke work index (from 512 (321) to 820 (470) mmHg.ml.m−2, p < 0.0001), while mean (SD) pulmonary vascular resistance index decreased by 24% (522 (330) to 399 (244) dyn.s.cm−5, p < 0.0001), and mean (SD) pulmonary artery pressure decreased by 10% (30 (8) to 27 (8) mmHg, p < 0.0001). Patients with pulmonary hypertension experienced a similar decrease in mean pulmonary artery pressure compared with those without, and they also had a slight reduction in mean (SD) pulmonary artery occlusion pressure (22 (6) down to 20 (6) mmHg, p = 0.044). We conclude that successful MitraClip treatment for mitral regurgitation acutely improves right ventricular performance by reducing right ventricular afterload, regardless of whether patients have pre‐operative pulmonary hypertension.


Aryl β : 2-dialkoxystyryl ketones(II), which are readily obtained from the corresponding chalkone dibromides, yield flavones on treatment with hydrogen bromide in acetic acid. These dibromides undergo many of the reactions already described for aryl p- alkoxystyryl ketone dibomides (J., 1937, 1798); in both the o- and the p-alkoxystyryl dibromides, the side-chain halogen atom adjacent to the nucleus containing the alkoxy- group is replaced by alkoxyl on treatment with alcohols.


Although borderline personality disorder (BPD) usually has its onset in young people, its diagnosis is often delayed, and specific treatment is usually only offered late in the course of the disorder. Over the past two decades, the explosion of knowledge about personality disorder has shown that BPD is neither a variant of normal adolescent development, nor a 'passing phase' of little consequence. In fact, BPD is associated with harmful personal, social, and economic consequences. This has provided solid ground for early diagnosis and treatment of both subthreshold borderline personality pathology ('indicated prevention') and full-syndrome disorder ('early intervention'). Over the past two decades, the Helping Young People Early (HYPE) programme has been developed and researched in Melbourne, Australia. HYPE is a comprehensive and integrated indicated prevention and early intervention programme for youth (15–25 years of age). HYPE is comprised of a service model and an individual therapy, and incorporates the principles of cognitive analytic therapy. HYPE primarily aims to alter the life-course trajectory of young people with borderline personality pathology by improving functional outcomes, interpersonal relationships, and self-management, developing support networks independent of mental health services, promoting adaptive help-seeking, and avoiding or reducing iatrogenic harms.


The first few seconds of the explosion of SN 1987A are modeled here using a 2D cylindrical geometry smooth particle hydrodynamics code. The success of the explosion is determined to be sensitive to the duration of the infall, the timing of the bounce, and the subsequent neutrino heating. A semianalytical model for the initial structure of the collapsed object is used to present two simulations that differ by the mass that has been allowed to collapse into a neutron star prior to the bounce. In the case of a short initial infall, the explosion fails due to excessive cooling. For a longer initial infall, the cooling is less and the explosion is successful although relatively weak. It is shown that in this case, a successful explosion is brought about by the presence of an entropy gradient which, combined with the gravitational pull of the neutron star, leads to extremely strong instabilities. The critical importance of the global circulation for the success of the explosion is demonstrated. 43 refs.


The use of parame t er plane curve s of output voltage magnitude versus one of the parame t ers as a means of obtaining t he freque ncy response of nonline a r networks was i nvestigat ed for ne tworks containing one nonlinear element, which was a function of the magnitude of the voltage across it. ( ' The re sults obtained were checked by d i gital simulation and it may be conc luded that the method is re liable. The me thod was also presented as a way of obtaini ng i nformat ion f or t he reshaping of network frequency response by introduction of the p r oper non linear elements.


Between October 1969 and September 1970, a sample of 1,806 northeastern Brazilian migrant families was collected to test several genetic hypotheses. A description of this population and the sampling techniques have been given [8, 9]. Due to the relatively high proportion of Negro admixture (~ 30%) [7, 8], it was possible to assemble a subsample of 28 families informative for Hb-MN linkage studies (i.e., one or both parents were segregating for both loci and the number of informative children was at least two). Fresh specimens of blood were typed for the MN system by two independent laboratories using rabbit anti-M and -N and lectin reagent from Vicia graminea. The Hb determination was performed by starch gel electrophoresis (Tris-borate, pH 8.6) on lysates of red blood cells stored at about -40° C in glycerol. The data were analyzed by sequential scores methodology [10, 11] at the data processing center of the Universidade de Brasilia.


− This study is to clarify the existing outstanding problems concerning (i) the nature of the exothermic reaction, (ii) the structure and composition of the spinel phase, and (iii) the mechanism of mullite formation. The structure of pre-mullite particles could be interpreted to be one where SiO 4 tetrahedron and AlO 6 octahedron are bonded at random by sharing oxygen atom. The composition of the spinel phase was most likely 2Al 2O35SiO2, and it is regarded that 4 Si 4+ and 4 Al 3+ occupy the available 8 tetrahedral sites and 12 Al 3+ occupy the available 16 octahedral sites leaving 4 octahedral sites being left vacancy. On this basis, the composition of the unit cell of spinel is 4Al vi 12[Al 4Si4] O32, where represents a vacancy in the octaheral coordination state. The sample passed through the spinel phase was transformed into the T-Mul lit at around 1,100oC and transformation of T-Mullite to O-Mullite could take pl ace about 1,250 oC. In the mullititation process as mentioned above, change of coordination number of Al 3+ ion and diffusion of SiO2 into the crystal cccured continuously with increasing calcination temperature until the 3 : 2 mullite is formed.


OUR bakers are not happy at present. According to the present Factory and Workshops Act an underground bakehouse cannot be used after January 1st, 1904, unless it is certified by the District Council of the neighbourhood where it stands, as being " suitable as regards construction, light, ventilation, and in all other respects." In face of this formidable, but rather vague warning, the bakers want to have some definite notion what the District Council might reasonably consider to be suitable. The Medical Officers of


Objective To search for a convenient and effective in vitro cell culture method to acquire highly purified Schwann cells.Methods The sciatic and brachial plexus nerve of three-day-old SD mice was treated with collagenase typeⅣand trypsin to remove the desmocytes on the Schwann cells,then explanted in the culture disk.Results Schwann cells grew more quickly from the treated nerve than the nerve without treating;the purity of Schwann cell population was up to 98%,significantly higher than the tissue adherent culture and tissue enzymatic digestion culture methods.Conclusion The modified method is convenient and feasible,may acquire a great quantity of highly purified Schwann cells for clinical research on repair of peripheral nerve defect.


The Health Service Executive is committed to the provision of safe high quality health
services. This guidance framework is based on a review of Guidance for Health Service
Providers on education and training requirements for non ICU Nurses to support the
provision of intensive care including care of the ventilated patient during Pandemic
(H1N1) 2009.


The objective of present study was to simultaneously isolate of isoflavone and soyasaponin compounds from the germ of soybean seeds. Soy germ flours were defatted with hexane for 48h at room temperature, and methanolic extracts were prepared using reflux apparatus at 90℃ for 6h, two times. After extraction, extracts were separated with preparative RP-C18 packing column (125 Å, 55-105 μm, 40×150mm), and collected 52 fractions were identified with TLC plate (Kieselgel 60 F-254) and HPLC, respectively. Among the identified isoflavone and soyasaponin fractions, isoflavone fractions were re-separated using a recycling HPLC with gel permeation column (Jaigel-W252, 20×500mm). Final fractions were air-dried, and the purified compounds of two isoflavones (ISF-1-1, ISF-1-2) and four soyasaponins (SAP-1, SAP-2, SAP-3, SAP-4) were obtained. Two isoflavone compounds (ISF-1-1, ISF-1-2) were acid-hydrolyzed for the identification of their aglycones, and confirmed by comparing with 12 types of isoflavone isomers. While the four kinds of soyasaponins were identified by using a micro Q-TOF mass spectrometer in the ESI positive mode with capillary voltage of 4.5kV, and dry temperature of 200℃. Base on the obtained results, it was conclude that ISF-1-1 is the mixture isomers of daidzin (43.4%), glycitin (47.0%), and genistin (9.6%), but ISF-1-2 is the single compound of genistin (99.8% <). On the other hand, soyasaponin SAP-1 is the mixture compounds of soyasaponin A-group (Aa, Ab, Ac, Ae, Af); SAP-2 is soyasaponin B-group (Ba, Bb, Bc) and E-group (Bd, Be); SAP-3 is soyasaponin B-group (Ba, Bb, Bc), E-group (Bd, Be), and DDMP-group (βg); SAP-4 is soyasaponin B-group (Ba, Bb, Bc), E-group (Bd, Be), and DDMP-group (βg, βa), respectively.


Culturing cells in order to produce substances, comprises setting a glucose limitation in the culture solution. Culturing cells in order to produce substances comprises setting a glucose limitation in the culture solution. The extent of glucose limitation (DGL) equals qGlc/Glc max, where qGlc is the current observed specific glucose consumption rate, and qGlc max is the maximum known glucose consumption rate for the cells in question. DGL lies between 0-1, where 0 is a complete limitation, and 1 represents no limitation (i.e. a complete glucose surplus). According to the invention the DGL is greater than or equal to the DGL that leads to the exclusive preservation of the cell and is 0.5.


Presence and the fact there is no to be affected by the film thickness of the deposited layer, to provide a cutting method of a glass substrate that allows the scribing of the glass substrate without damaging the film formation. Table thin deposition layer such as a resin film to (1a) glass substrate (1) which is formed, a glass substrate (1) in a strip by removing a part of the deposition layer (1a) in a strip on one side as a tool to out peeling means (202) comprises a wheel cutter (14a) for forming a scribe for cutting along the band-like region of the exposed glass substrate (1), the glass substrate 1 along the scribe the decoupling.


The invention relates to a preparation method of a chlorine dioxide skin gel, which is characterized by comprising the following steps of: mixing ethylene diamine tetraacetic acid with purified water to obtain a solution A; heating and then cooling one half of the solution A, and placing in a refrigerator to obtain a solution B; mixing the other half of the solution A with glycerol to obtain a solution C; swelling Carbomer 940 in the solution C and regulating the pH value by using a sodium hydroxide aqueous solution to obtain a gel substrate; uniformly stirring a chlorine dioxide aqueous solution, the solution B and the gel substrate after mixing, and then carrying out vacuum deaeration to obtain the chlorine dioxide skin gel. The chlorine dioxide skin gel has the advantages of rapidity and durability, safety and no toxicity, wide application and high efficiency and the functions of sterilization, disinfection, bleaching and deodorization and is hardly influenced by environment (such as temperature, pH value, organic matter and the like) when in use.


Commercial cast irons consist of many phases based on the iron-carbon-silicon system. These alloys usually contain impurity levels of certain reactive elements. The general conditions under which the eutectic liquid solidifies primary determine the size and distribution of the graphite phase which, in turn, is a major factor controlling mechanical propierties. Addition of small amounts of magnesium and/or ceríum to the technícal cast iron melts during solidification causes graphite to form lamellae to spheroidal shape, leading to the well known spherulitic cast iron or nodular cast iron or ductile iron.


Suicide is a devastating outcome of major public health importance. In the United States, suicide is the 11th leading cause of death across all ages and the seventh leading cause of death in males. Suicide rates vary considerably across population subgroups. U.S. military veterans may have an increased risk of suicide compared with the general population. Veterans represent around 10 percent of U.S. adults but account for 20 percent of completed suicides, and approximately 18 to 22 veterans die from suicide each day. In addition, a considerable body of research suggests an increased risk for suicide among veterans seeking services from the Department of Veterans Affairs (VA). The increased risk for suicide among veterans has recently captured tremendous public attention and led the VA to declare the prevention of suicide to be a major national priority. The VA has launched comprehensive suicide prevention efforts and has collaborated with the Department of Defense (DoD) to develop a clinical practice guideline based on best available evidence and expert consensus. This article discusses considerations for suicide risk assessment and intervention, mostly derived from the VA/DoD clinical practice guideline. It also briefly reviews the VA suicide prevention program and the importance of veteran suicide risk assessment in primary care settings. Language: en


Using dispersion compensation chirped Fiber Bragg Grating (CBG), 2500km-10Gbps transmission system on G.652 fiber is successfully demonstrated without electric regenerator. The CBG has the perfect performance: The group delay ripple is small (about ± 15ps), the group delay is large(about 2600ps/nm), and the insertion loss is low (only 4dBm). The system has 12 wavelength channels. The channel space is 0.8 nm (100 GHz), according to the wavelength standard (in C band) of the ITU- T suggestion. At 2060km in the system, power penalty is about 2dBm (condition: NRZ, BER=10-12,PRBS=1023-1); At 2530km, Bit Error Ratio (BER) is free with high power penalty. However, the result is superior to the system using Dispersion Compensation Fiber (DCF) under the same condition.


Internet networks are handling increasing volume of traffic than ever before. This data is mainly associated to sensitive, distributed, and multimedia applications. In the past years, much attention has been paid to the way network infrastructure must be designed and developed in order to handle the challenges of delivering high quality services for applications such as VoIP and streaming video.


Bluegill (Lepomis macrochirus) is the dominant fish species in a 67-ha cooling reservoir for a nuclear reactor on the Savannah River Site in South Carolina. Mortality and breeding season of bluegill were strongly influenced by reactor operations, which often produced temperatures of 40–60 °C in portions of the reservoir. Late spring and summer reactor operations caused ~ 90% mortality of bluegill. This mortality was largely associated with reactor restarts. Survivors occupied small thermal refuges in coves. Elevated fall and winter temperatures allowed an extended breeding season, although extremely high summer temperatures appeared to inhibit breeding. Bluegill depended primarily on benthic food resources, including dipterans and microcrustaceans. Despite the great variation in environmental conditions and diets, body condition of surviving bluegill was nearly constant between April 1985 and January 1986. Factors that contribute to the success of bluegill in this system include high thermal tolerance, br...


Abstract Background Investigators conducting prospective clinical trials must report patient flow using the Consolidated Standards of Reporting Trials (CONSORT) statement. Depending on how data are collected, this can be a laborious, time-intensive process. However, because many trials enter data electronically, CONSORT diagrams may be generated in an automated fashion. Objective Our objective was to use an off-the-shelf software to develop a technique to generate CONSORT diagrams automatically. Methods During a recent trial, data were entered into FileMaker Pro, a commercially available software, at enrollment and three waves of follow-up. Patient-level data were coded to automatically generate CONSORT diagrams for use by the study team. Results From August 2012 to July 2014, 1,044 participants were enrolled. CONSORT diagrams were generated weekly for study team meetings to track follow-ups at 1, 6, and 12 months, for 960 (92%), 921 (90%), and 871 (88%) participants who were contacted or deceased, respectively. Reasons for loss to follow-up were captured at each follow-up. Conclusion CONSORT diagrams can be generated using a standard software for any trial and can facilitate data collection, project management, and reporting.


An efficient numerical algorithm for treating earth models composed of fluid and solid portions is obtained via straightforward modifications to a 3D time-domain finite-difference algorithm for simulating isotropic elastic wave propagation.


In the designing of engineering,there're always a lot of optimization problems.In order to solve these,the engineer must to design programs.But it would be difficulty specially,with the use of MATLAB,all of these would be easy to be solved.This article introduce a way to imitate a curve with the help of MATLAB.


We describe METEOR, an automatic metric for machine translation evaluation that is based on a generalized concept of unigram matching between the machineproduced translation and human-produced reference translations. Unigrams can be matched based on their surface forms, stemmed forms, and meanings; furthermore, METEOR can be easily extended to include more advanced matching strategies. Once all generalized unigram matches between the two strings have been found, METEOR computes a score for this matching using a combination of unigram-precision, unigram-recall, and a measure of fragmentation that is designed to directly capture how well-ordered the matched words in the machine translation are in relation to the reference. We evaluate METEOR by measuring the correlation between the metric scores and human judgments of translation quality. We compute the Pearson R correlation value between its scores and human quality assessments of the LDC TIDES 2003 Arabic-to-English and Chinese-to-English datasets. We perform segment-bysegment correlation, and show that METEOR gets an R correlation value of 0.347 on the Arabic data and 0.331 on the Chinese data. This is shown to be an improvement on using simply unigramprecision, unigram-recall and their harmonic F1 combination. We also perform experiments to show the relative contributions of the various mapping modules.


It is generally accepted that in typical Addison's disease, the destructive lesion of the suprarenal glands must be of a chronic progressive nature such as might be associated with amyloidosis, tumor formation, and tuberculosis. However, modern statistics suggest that atrophy and aplasia of the cortex account for 50 per cent of the cases. In the extensive literature on blastomycosis caused by Paracoccidioides brasiliensis or Lutz' disease (Fonseca and Le&o,' Almeida,24 Almeida, Lacaz, and Cunha,5 Lima,6 Motta and Pupo,7 Moore,8 Motta,9-11 ifio 12 Fonseca, 1314 Fialho,'5 Versiani and Bogliolo 16), lesions in the adrenal glands were seldom mentioned. Azevedo17 was the first to report extensive necrotic changes in one case and brief references to the subject were made afterwards by Chirife,'8 Prado,19 and by Fialho.'5 In 2 patients necropsied at the Division of Pathology of this Institute, the lesions in the suprarenal glands were marked and comparable in extent to those reported as due to the tubercle bacillus in cases of Addison's disease. As no reference to the syndrome of adrenal insufficiency is made in the literature on South American blastomycosis, we present our findings which are confirmative of those of Azevedo17 in order to stimulate further investigations on the functional significance of such changes. New data were obtained in connection with the cause of the necrosis so often found in lesions produced by P. brasiliensis.


This paper discusses the design on power communication resource management system based on VisualNet platform.It introduces the method of establish database,and the operations of equipment positioning and asset statistical management etc.The design software enjoys faster speed,higher efficiency and more flexible management ability.


It is that the of by a free-living in an is influenced more by social conditioning and emotional factors than by physiological control. makes it difficult to investigate the mechanisms of food intake in humans; there are so many possible factors to consider.


The present invention hydroximoyl - heterocyclic derivatives, a method for preparing them, intermediate compounds for their preparation, their use as fungicides active agent, in particular, true killing in the form of fungicide compositions bacteria their use as agents active agent, and a method of controlling phytopathogenic fungi using these compounds or compositions, in particular, to a method of controlling phytopathogenic fungi of plants.


Agricultural productivity is a key component of the Indian economy, for over 70% of India's agricultural people, agriculture is their main source of income. Plant diseases are the main reason why agricultural productivity has declined in both quality and volume. It is extremely difficult for a farmer to recognize and manage plant illnesses. The majority of plant illnesses manifest in the leaves of the affected plant. The illness that harms a plant is recognized using leaf photos. This proposed system focuses on certain deep-learning techniques to identify plant illnesses while also proposing which crop variety is optimal for production in that specific area. To make the proposed system more robust, proper training and testing have been shown with leaf datasets. The information set contains both healthy and unhealthy leaf images which are reported. First, the model suggests the best crop for the farmer using machine learning methods like Support Vector Machine (SVM), K-Nearest Neighbor (KNN), Gaussian Naive Bayes (GNB), and Decision Tree (DT). Lastly, the disease is detected by using a deep learning technique called Convolutional Neural Network (CNN) by comparing the input image and trained image. This proposed system would be capable of solving real-world problems and be a better approach concerning other state-of-the-art methods.


presents crack growth resistance data performed on the crack line wedge loaded (CLWL) specimens in some aluminum, steel, and titanium alloys. The /-integral was used for the expression of the obtained data and its values were determined analytically by using the elastic fracture theory, the Dugdale model and the Prandtl-Reuss theory. The author of the present discussion would like to add some further comments on this paper related to the use of the above-referred three models for predicting the behavior of the CLWL speci mens in the elastic and especially in the plastic region of de formation.


Objective To extract the effective fraction of Herba cepbalanoplosis segeti and prepare the rat gastric irrigation.Methods The effective fractions of Herba cepbalanoplosis segeti were extracted by systematic solvent method. The extract solution Herba cepbalanoplosis segeti of rat gastric irrigation were prepared by different ways,such as solubilization with tween 80,suspension with CMC-Na solution and dissolution with edible oil.Moreover,the stability of solution was observed.Results The yield rate of the ethanol extract was maximum.The solution of the ether and ethyl acetate extract were prepared well with salad oil as solvent;whereas the solution of the ethanol extract was prepared well with CMC-Na solution at higher temperatures.Conclusion The effective fraction of Herba cepbalanoplosis segeti can be extracted well by systematic solvent method and the preparation methods of the extract solution of rat gastric irrigation are feasible and stable.


In this paper, tin oxide (SnOx) semiconductor is synthesized using a sol-gel process. Thermal oxidation process is used to grow a silicon dioxide (SiO2) film on an n+-Si substrate as the gate dielectric layer. A significant difference in the transfer characteristics is observed for the SnOx/SiO2 samples annealed at 200-400 °C. For the 200 °C-annealed sample, the conductivity of the SnOx semiconductor layer cannot be controlled by the n+-Si gate electrode. When the annealing temperature increases to 300 °C, a significant switching behavior induced by the gate bias can be obtained. However, an obvious increase in the off-sate current is found as the annealing temperature further rises to 400 °C. The leakage current of the SiO2 gate dielectric is also found to be dependent on the concentration of the SnOx precursor solution. This study is helpful for developing oxide semiconductors for future flexible electronic applications.


how many of the well-known white leaders of the Social Gospel were extensively and publicly involved in the pursuit of civil rights and better conditions for African Americans. Charles M. Sheldon, e.g., is known mostly for his Social Gospel novel, In His Steps. But Sheldon spent more than a decade in ministry with the African Americans of Topeka, Kansas, and wrote also another novel based on those experiences. One wonders whether the general inattention to these activities among historians is not a more important manifestation of racism than many of those of which the Social Gospel movement itself was supposedly guilty. In any case, W. has given us a balanced and readable introduction to a legacy which should be far better known.


Fas/CD95 is a critical mediator of cell death in many chronic and acute liver diseases and induces apoptosis in primary hepatocytes in vitro. In contrast, the proinflammatory cytokine tumor necrosis factor α (TNFα) fails to provoke cell death in isolated hepatocytes but has been implicated in hepatocyte apoptosis during liver diseases associated with chronic inflammation. Here we report that TNFα sensitizes primary murine hepatocytes cultured on collagen to Fas ligand (FasL)–induced apoptosis. This synergism is time‐dependent and is specifically mediated by TNFα. Fas itself is essential for the sensitization, but neither Fas up‐regulation nor endogenous FasL is responsible for this effect. Although FasL is shown to induce Bid‐independent apoptosis in hepatocytes cultured on collagen, the sensitizing effect of TNFα is clearly dependent on Bid. Moreover, both c‐Jun N‐terminal kinase activation and Bim, another B cell lymphoma 2 homology domain 3 (BH3)–only protein, are crucial mediators of TNFα‐induced apoptosis sensitization. Bim and Bid activate the mitochondrial amplification loop and induce cytochrome c release, a hallmark of type II apoptosis. The mechanism of TNFα‐induced sensitization is supported by a mathematical model that correctly reproduces the biological findings. Finally, our results are physiologically relevant because TNFα also induces sensitivity to agonistic anti‐Fas–induced liver damage. Conclusion: Our data suggest that TNFα can cooperate with FasL to induce hepatocyte apoptosis by activating the BH3‐only proteins Bim and Bid. (HEPATOLOGY 2011.)


NASA has been collaborating with the Federal Aviation Administration (FAA) and aviation industry partners to develop and demonstrate new concepts and technologies for the Integrated Arrival, Departure, and Surface (IADS) traffic management capabilities under the Airspace Technology Demonstration 2 (ATD-2) project. One of the goal of The IADS capabilities in the ATD-2 project is to increase predictability and increase throughput via improving TMI compliance. The IADS capabilities that will impact TMI compliance are built upon previous NASA research, the Precision Departure Release Capability (PDRC) [1]. Benefit analysis results indicated substantial opportunities to reduce taxi delays for both departures and arrivals and increase throughput and predictability by integrating these capabilities [2].


The subject of this study is (1) to analyze dynamic level in Kurnia group, (2) to analyze linkage farmers characteristic with the dynamic group in Kurnia group, and (3) to analyze linkage of a dynamic group with successful partnership formula. This study was conducted by a survey in Kurnia Group. Technical sampling was determined by purposive sampling. The respondents were 30 people who had running activities in the group. The result shows that firstly, the Generally dynamic group in Kurnia group dynamic. Dynamic group in Kurnia depend of group aim, group structure, task function, training group etc. Successful in partnership show success, it depends on income (86,7%) dan Productivity (90%). Experience of a farmer has a linkage with the dynamic group. Age of respondents, occupation does not have a linkage with the dynamic group. Generally, there is no linkage of the dynamic group with a successful partnership formula. This indicated that dynamic group does not influence the successful partnership formula.


For the new earth-observation technique-multibaseline SAR(Synthetic Aperture Radar) interferometry,this paper analyzed its development history,application fields and the existing systems' status.And,it discussed the research progress for the key technique during data processing,the application potential in fields of surveying and mapping,inspecting of ocean and buildings,hydrology,land subsidence monitoring and so on.Eventually it emphasized the relative research focuses and future development trend applied in terrain mapping,and provided a primary analysis of some questions to be resolved.


BAXI, HEMANT K., M.S., August 2016, Mechanical Engineering Teleoperative Control Plus Simulation and Analysis of Walking for the DARwIn-OP Humanoid Robot Director ofThesis: Robert L.Williams II The thesis attains the objective of developing a teleoperative system for controlling the humanoid robot DARwIn-OP. The user interface and the hardware is installed and tested. The idea behind developing a teleoperative robot is to use the robot in times of emergency and other major crises without endangering human life. The hardware developed used Bluetooth technology and the user interface was developed using Android Programming Environment. Code is developed to make the robot work by inputing command using the tablet running on Android. The other objective of analyzing the human walk and a robot walk is also attained. Hip joint, Knee joint, Ankle joint are compared for a human walk with respect to joint angle, joint angular velocity and joint angular acceleration. In order to make DARwIn-OP walk more energy efficient it is proposed to use the ZMP method with Genetic algorithm for optimizing the Gait parameters. Darwin-OP has a programmable walking controller to help it locomote while in soccer mode. This controller generates a sinusoid for lateral body motion. It also generates a step period to help it move forward. The walk path generated from the controller appears to create short and choppy steps for Darwin-OP [33]. A new method for walking gait generation for Darwin-OP is proposed using ZMP and Genetic algorithm for optimizing the walking 4 gait of Darwin-OP. The ZMP method is able to generate a more stable walk path with longer strides. [34].


ABSTRACT In practical data production process of ZiYuan-3 (ZY-3) optical satellite, the quality of massive panchromatic (PAN) products is usually measured with multiple quality metrics. Although the existing metrics have been widely used in practice and obtained good performance, they have some limitations: (1) there are so many quality metrics that makes it difficult for users or operators to directly judge whether the imagery is acceptable or not; and (2) a specific quality metric can only measure a certain aspect of image quality and is often not designed from the perspective of human visual system (HVS), leading the objective evaluation result inconsistent with subjective one. To tackle the aforementioned problems, we propose an integrated visual quality assessment (VQA) method to predict comprehensive quality scores for ZY-3 sensor calibration (SC) PAN products. In the proposed method: (1) we exploited eight quality elements that have significant influences on the visual quality of SC PAN products; (2) we constructed a database composed of 360 ZY-3 SC PAN images and the corresponding subjective mean opinion scores (MOS); (3) we introduced generalised regression neural network to combine the extracted quality elements of the images and their MOS and obtained the integrated VQA result. Experimental results on the database showed that the proposed method achieved high accuracy of predicted quality scores and well consistency with HVS, indicating the effectiveness and reliability of the presented approach.


Background: The self‐report version of the Panic Disorder Severity Scale (PDSS‐SR) has been developed recently and has demonstrated good psychometric properties. However, there is no cross‐cultural evaluation of this scale. The purpose of this study was to confirm the reliability and validity of the PDSS‐SR in Korean subjects. Methods: We studied 148 patients with principal DSM‐IV diagnoses of panic disorder who underwent formal structured diagnostic assessment and the PDSS interview. The participants completed self‐report measures including the PDSS‐SR, Anxiety Sensitivity Index‐Revised, Albany Panic and Phobia Questionnaire, Beck Depression Inventory, Beck Anxiety Inventory, and Spielberger State–Trait Anxiety Inventory‐Trait Version. Results: The PDSS‐SR had a single‐factor structure, with all seven items having salient loadings. Cronbach's α for the PDSS‐SR was .88 and intraclass correlation coefficient was .71 between PDSS‐SR and PDSS. Also, the scale showed excellent 1‐day test–retest reliability and demonstrated significant correlation with other anxiety‐related measures. In addition, the PDSS‐SR was sensitive to change with pharmacological treatment. Conclusions: The findings of this study strongly support the reliability and validity of the PDSS‐SR. It is expected that this scale will be helpful in clinical settings and research protocols in Korea. Depression and Anxiety, 2009. © 2009 Wiley‐Liss, Inc.


The present invention provides a kind of blow-by gas and to prevent water penetration of cementitious panel outer sheath. Also it provides a method for producing a body of highly efficient air / water barrier cementitious panels of the outer sheath film.


The decomposition products of GIS basin insulators have characteristic components under four conditions: different defects of GIS basin insulators, cracks and surface discharge of insulation parts inside GIS, abnormal heating of silicon packing basin insulators under steady state current, and particulate discharge of insulation parts. The characteristic components of decomposition products of SULFUR hexafluoride are introduced. Different mechanisms of decomposition products in partial discharge defects and abnormal heating defects were analyzed. The effects of partial discharge defects, abnormal heating defects and adsorbents on the decomposition products were studied.


The study examines the effect of fiscal and monetary policies on economic activities in South Africa while attempting to identify the role of uncertainty. The study utilized quarterly time series data using the variables of income tax, consumption tax, capital tax, and government expenditure to measure fiscal policy uncertainty while interest and inflation rate variables were used to measure monetary policy uncertainty. Also, real gross domestic product, real consumption, real investment, and employment were used to measure economic activities. The partial least squares structural equation model (PLS-SEM) was used for analysis and result presented for measurement and structural models. Results revealed the existence of policy uncertainty in the South African economy which tends to reduce the level of economic activity as uncertainty increases. This result informs of the need for policy makers to minimally reduce uncertainties for both fiscal and monetary policies for the economy to improve.


concanavalin A to visualize glycosylated subunits. Mycelial plasma membranes fromstrains carryingmutations affecting ascosporeswerealso analyzed. Twoofthemutantstrains were showntohaveaberrant two-dimensional membrane subunit patterns. The correlation ofthese abnormalities withtheknownelectron microscopic evidence foraberrations oftheir ascospore-delimiting membrane during ascosporegenesis isdiscussed. Analyses ofmutations affecting ascusdevelopmentinNeurospora crassa havepromise for furthering theunderstanding ofdevelopmental processes infungi. Thewidevariety ofmutant ascus phenotypes available forstudy hasundergoneextensive genetic analysis (15). Sofar, however, themolecular basis ofmutations affecting ascospores hasbeenelusive, butrecent comparative ultrastructural studies ofascus development inwild-type, mutant giant spore, and indurated strains ofN.crassa (A.M.Srband M.Basl, manuscript inpreparation) haveyieldedclues toapossible underlying defect. When viewed withanelectron microscope, these mutantstrains appear tohaveaberrations intheir ascospore-delimiting membrane. Thisobservation hasledtoacomparative investigation ofthe molecular components ofmembranes isolated fromwild-type andmutant N.crassa strains. Although techniques arenotavailable forisolatingascospore-delimiting


BIRCH(Balanced Iterative Reducing and Clustering Using Hierarchies) clustering algorithm is a new algorithm for large datasets,but this algorithm has some defects.Considering these defects,on the threshold in the CF-tree based on sum of deviation square to meliorate the pertinence between the clusters,the split factor is defined by the max diameter to overcome defect of the factor from the experience.At last,the improved BIRCH clustering algorithm to analyze the gene graphical representation data elementary is brought.


Incidents are the cause for excess travel delays, and elimination of comfort and safety to the motorists. Dedicated to the testing and evaluation of technologies applied in the domain of incident management, ERMIS (Emergency Response and Management Information System) constitutes the testbed of an integrated incident management system, which operates in Thessaloniki Greece. It has been developed within the context of the European and National Research funds, pursuing fast and automatic incident detection, through the implementation of video image processing technology, provision of appropriate information regarding the incident characteristics through the closed circuit television- (CCTV-)network, and spontaneous notification of response actors and automated identification of appropriate response units and response actions. Within the scope of continuing its contribution in the domain of incident management, ERMIS constitutes the main Greek site for the development of an integrated traffic and incident management system, which aims at the minimization of travel delays caused to incidents. The present paper presents the results provided by a platform, which emulates traffic flows and traffic incidents and simulates the impact of integrated traffic and incident management practices on travellers' behaviour. This platform intends to play the role of a decision support tool that gives the means for testing alternative practices in a simulated environment, in order to select the optimum to be implemented upon certain traffic and incident situations. Finally, the paper presents concrete data resulted from the testing of alternative traffic management schemes under different traffic and incident conditions, and proposes specific actions for the incorporation of this platform in an operational traffic management system.


The average rate of configuration transition of the (dAT) copolymer has been determined by the study of the spectrum of light scattering. For the alkaline transition of (dAT) at 18.7°C, pH = 11.0, and ionic strength of 0.1M Na+, we find a rate τR−1 = 2.33 ± 0.21 × 103sec−1. This compares favorably with previous measurements obtained by the temperature‐jump technique. Simultaneously, we have measured the linear diffusion coefficient within the transition region to be D = 2.91 ± 0.14 × 10−8cm2/sec. There is a 6%–10% variation of the diffusion rates between the samples at the low‐pH (10.4) helical conformation and at the high‐pH(11.6) random coil conformation.


: Forensic imaging is a new field with increasing application all over the world. However, its role in legal medicine is controversial, mostly due to the use of undefined and unclear terms. The aim of this article is to describe forensic imaging and to explain the various techniques that pertain to it. Essentially, these methods consist of radiological methods such as conventional radiography, computed tomography, and magnetic resonance imaging, but other techniques such as 3D surface scanning are also employed. Computed tomography can be combined with minimally invasive strategies such as image-guided sampling or post-mortem angiography. We provide an overview of the advantages and limitations of these methods, which must be identified and understood to enable correct application.


Dementia-related agitation is a common and costly condition that is distressing, debilitating, often dangerous and usually difficult to treat in a safe and reliable manner.1 Clinicians are caught between the 'devil' of medications with unfavourable risk–benefit profiles2 and the 'deep blue sea' of non-pharmacological interventions perceived as impractical and lacking in evidence for benefit.3 Before opting for any intervention, it is essential to rule out underlying causes of agitation and then consider strategies such as environmental modification, sensory interventions and family involvement/support.


This study aims to show that there is a positive relationship between leverage, liquidity, and profitability on financial statement disclosures, and this study wants to show that auditor quality is able to improve the positive relationship. This study uses secondary data on Indonesian manufacturing companies in 2017. This study uses purposive sampling so that the research sample is 149 companies. This study uses total debt to total assets ratio for proxy leverage, current ratio to proxy liquidity and returns on assets to proxy profitability. The results of this study indicate that in Indonesian manufacturing companies in 2017, leverage has a positive effect on financial statement disclosures required by the OJK, but profitability and liquidity do not show any influence on financial statement disclosures required by the OJK. Auditor quality can directly improve the disclosure of financial statements, so that good auditor quality is able to encourage companies to comply with the financial statement disclosure standards of the OJK. On the other hand, auditor quality is proven to be unable to improve the disclosure of financial statements along with the increase in financial performance. The size of the company proved to be a factor that influences the disclosure of financial statements but has a negative effect so that these results show differences with previous studies where the overall research shows that the size of the company has a positive effect on the disclosure of financial statements. The results of this study can be input for regulators in making financial statement disclosure regulations that can increasingly be fulfilled for larger companies and companies with better financial performance. This study provides novelty by presenting auditor quality as a variable that is capable to strengthen financial performance against financial statement disclosures, other than that it positions the size of the company as a control variable and using the OJK (Otoritas Jasa Keuangan/Financial Authority Sevices) checklist totaling 1231 items for financial statement disclosures that have never been studied previously.


Recently, excellent three-dimensional (3-D) images can be quickly and easily obtained using helical scan CT, a procedure of continuous scanning CT to acquire volume data. 3-D CT imaging was applied to 66 surgical cases of facial fractures and it was helpful not only to evaluate facial fractures, but also to plan operations except for in cases of blowout fractures.The quality of 3-D CT image depended on the slice thickness and on the slice interval at CT scanning, and we also found that the threshold value of CT number at which 3-D images were reconstructed influenced the quality of the 3-D imaging.However, 3-D imaging does not necessarily provide additional new information if two-dimensional (2-D) CT scans have been performed, and 2-D CT images also provide superior fracture details. Thus, based on our clinical experiences we suggest that 2-D CT image and 3-D image reconstructions are complementary procedures.


Abstracts Diluted water solutions of anti-oxidant potassium phenosan, kept before explorations in "usual" conditions and in conditions of "permalloy container", i.e. shielding of solution from the influence of external low-frequency electromagnetic and/or geomagnetic fields, were studied. It is shown that in solutions kept in shielded conditions in the area of high dilution with a concentration of solutions lower than "threshold", nanoobjects called "nanoassociates", are not formed, and anomalous physicochemical and biological properties observed in solutions kept in "usual" conditions, are not found. We conclude that anomalous physicochemical and biological properties of highly diluted water solutions of potassium phenosan made under "usual" conditions are determined by "nanoassociates", in which an external low-frequency electromagnetic and/or geomagnetic field is a necessary condition of the formation.


The Geneva negotiations on a comprehensive test ban (CTB) treaty recessed on September 7 for five months without making any significant progress. The heavily {open_quotes}bracketed{close_quotes} draft treaty revealed that the negotiators from 37 countries had failed to agree on a single major issue. Little chance remains to complete the treaty before the nuclear Non-Proliferation Treaty (NPT) review and extension conference begins next April 17. The prospect of continued gridlock does not auger well for the NPT`s indefinite extension - a principal US security policy objective - since many non-nuclear-weapon states consider the test ban the litmus test of the nuclear-weapon states` willingness to meet their obligations under Article VI of the NPT.


Water is the most precious natural material. Water quality is strongly influenced by the social environment such as population density and social density. Tuk River is one of the Kali Garang River tributary that crossed markets and residential areas that have the potential for contamination by domestic waste. Region through which the river, these include the Sampangan Village and Bendan Ngisor Village Gajahmungkur District. The focus of this research is the behavior of a few clusters of communities around the Tuk River related domestic waste water disposal in terms of aspects of knowledge, attitude and action. Primary data were collected by conducting interviews using the questionnaire tool. Secondary data in the form of a general description of the Tuk River and statistical data obtained from relevant agencies. The populations in this study were residents in the Bendan Ngisor Village and Sampangan Village. The design of the study sample was selected proportionally based on location of residence. The numbers of samples taken from each cluster of residence and selected purposively. Selected sample is the sample that living near the Tuk River and dispose of domestic waste water into the Tuk River. The data have been collected were analyzed by analysis of frequency tables, cross tabulation and simple correlation analysis. The results showed that the behavior of middle settlement cluster of respondents to domestic waste water on aspects of knowledge and attitude better than any other settlement clusters. However, in action aspect, respondents in small settlement cluster better than the other two clusters of settlements. The level of education has a fairly good correlation in the attitudes of respondents, but still less correlated to the knowledge and actions in respondent's domestic waste water disposal into the river bodies. The fact that encountered in the field, indicating that the action of respondents in addition to dispose of domestic waste water is influenced by the knowledge and attitudes are also influenced by the existing drainage system in the neighborhood. Keywords: Tuk River, domestic waste water


The interfacing multiple-model extended Kalman filter (IMM-EKF) is proposed here as a modification of the extended Kalman filter (EKF). In this algorithm, two multiple-model EKF groups are built, one group is the optimum model, and the other is the noise model. Each model group is created by multiple models, and it will get good performance at stable state and robust ability when disturbance occurred. The algorithm gets the estimation value by mixing the outputs of the different model in different weightings, and the calculation of weightings is researched. Whether the IMM-EKF can give better estimation performances and robust ability than the EKF for speed estimation of induction machines is explored in this paper. Via simulations and experiments, estimated error and the change of flux linkage by disturbance based on the IMM-EKF and EKF is compared. The simulation results show that the IMM-EKF has the better estimation performance of antigross error than the EKF.