We present familial tuberous sclerosis (TS) case complicated by COVID-19. COVID-19 aggravates the course of TS and may lead to a fatal outcome. We review the role of mTORC1 (mechanistic/mammalian Target of Rapamycin Complex 1) in the development and functions of the nervous system and the pathogenesis of TS and COVID-19 with emphasis on the involvement of the brain and lungs. We observed that COVID-19 worsens the course of epilepsy in patients with TS. In TS patients, lymphangioleiomyomatosis may predispose to SARS-CoV-2 invasion into the respiratory system because of the increased expression of ACE2 and TMPRSS2 in type II pneumocytes and thus may worsen the prognosis. We also review the current data on the continuation/termination of everolimus administration in patients with TS associated with COVID-19.


The status is that small and medium enterprises generally lack of strategic management,from which the need for China's small and medium construction enterprises to implement the strategic management it ana-lyzed according to characteristics of these companies.It also expanded on the stages in detail of strategic man-agement in them.It is believed that carrying out strategic management is the key point of small and medium construction enterprises' survival and sustainable development in a rat race.


Does online campaigning foster 'echo chambers' and exacerbate the polarisation of society? On Facebook, Leave and Remain supporters behaved very differently. Pro-Remain users commented mainly on like-minded Facebook pages. By avoiding confrontation with their political opponents, Remainers showed behaviour characteristic of an 'echo chamber'. In contrast, Leavers spread their messages on pages spanning the ideological spectrum, and they sought to incite confrontation by frequently posting on the walls of their ideological adversaries. Michael Bossetta (University of Copenhagen), Anamaria Dutceac Segesten (Lund University) and Hans-Jorg Trenz (University of Copenhagen) chart citizens' media and campaign cross-posting behaviour to examine patterns of political participation on Facebook.


. We investigate a version of Alberti's rank one theorem in Ahlfors regular metric spaces, as well as a connection with quasiconformal mappings. More precisely, we give a proof of the rank one theorem that partially follows along the usual steps, but the most crucial step consists in showing for f ∈ BV( X ; Y ) that at k Df k s -a.e. x ∈ X , the mapping f "behaves non-quasiconformally".


The present research compared interindividual and intergroup coalition processes. We examined whether groups are more likely to form small coalitions than individuals, and whether this tendency would depend on the social value orientation of the coalition party. Consistent with our hypothesis, results revealed that proselfs formed more small coalitions in intergroup settings than in interindividual settings whereas prosocials formed a similar number of small coalitions in both intergroup and interindividual settings. These and complementary findings add credence to the claim that people who are self-oriented are more likely to exclude others to maximize their own payoff and that such processes are especially pronounced in intergroup settings.


This paper describes our work of applying modem software engineering methodologies such as model-driven development and product-line engineering to the development and maintenance of technical supporting systems in the domain of search and rescue. We propose an extensible, domain-specific, graphical modeling language and toolset that allow software developers of search and rescue systems to rapidly compose and generate their applications from a set of predefined graphical primitives that represent the common building blocks of SAR applications. A case study for the proposed toolset is also presented.


This study considers the potential of a variable investment tax credit to relieve the pressure of a contracyclical monetary policy on the housing and State and local government sectors.


General constraints on supersymmetric extension of axion models are derived, in particular paying careful attention to the cosmological effects of saxion. It is found that for every mass range of the saxion from keV to TeV, severe constraints on the reheating temperature are imposed. Implications on inflation models are also discussed.


Summary form only given. We have developed an experimental test bed to characterize the performance of a laser-triggered spark-gap switch, particularly as it transitions from photoionization to current conduction. The switch is triggered by a focused 532-nm wavelength beam from a Q-switched Nd:YAG laser with a pulse duration of about 10 ns. The trigger pulse is delivered along the longitudinal axis of the switch, and the focal spot can be placed anywhere along the 5-mm, gas-insulated gap between the switch electrodes. Laser-triggered discharges consisting of pulses with as much as 15 kV across the switch and 4 kA of current through it have been obtained. The discharge through the switch is driven using an underdamped circuit that generates pulses lasting about 500 ns. The test bed is designed to support a variety of working gases (e.g., Ar, N2, He, H2) over a range of pressures. Electrical and optical diagnostics are used to measure switch performance as a function of parameters such as charge voltage, trigger pulse energy, insulating gas pressure, and gas species. Among these diagnostics is a two-color (532-nm and 1064-nm wavelengths) Mach-Zehnder imaging interferometer system in which the probe beams propagate transverse to the longitudinal axis of the switch, along which the current flows. The interferometer will be used to simultaneously measure plasma free electron and neutral gas densities profiles within the switch gap at different points in time during the discharge. Experimental results obtained to date will be presented. Data from our experiments will be used to determine the minimum conditions necessary to induce breakdown and conduction of a gas-insulated electrode gap in the presence of laser-induced photoionization. The electromagnetic particle-in-cell code ICEPIC will be used to produce numerical simulations of the laser-initiated arc discharge, and the experimental data will be used to validate the calculations.


Power system state estimation determines the optimal system states based on the network model and the gathered measurements from the system. Weighted least square (WLS) state estimation is the most commonly used method in power industry, and it may suffer divergence under stressed system conditions. This paper investigates the impacts of variations of line power flow increment and topology errors on convergence property of the WLS state estimator. A simple 3-bus system and the IEEE 118-bus system are used as the test cases and simulation results are reported. Furthermore, this paper also studies the effect of adding phasor measurement unit (PMU) voltage phasor measurements to convergence property of WLS state estimation. Simulation results show that adding PMU measurements could generally improve the robustness of state estimation, but there exists a few special cases violating the rule and needs to be taken care when applying PMU measurements in state estimation.


Fluorescence changes following the excitation in a Pacinian corpuscle were examined under the fluorescence-microscope by using ANS (Anillino naphthalene-sulfanic acid) or Acridine-orange which were injected through the cat's saphenous vein. And the observation of the fluorescence on an Ameba membrane was done too.1) An increase of fluorescence was taken as a picture after repetitive stimuli when a certain concentration (0.5 to 1.0% 1ml/Kg) of these dyes was used.2) When the stimuli were not applied to the corpuscle any increase was not shown on the picture.3) If the fluorescent dyes were directly added in Ringer-Locke's solution not in the vein, any fluorescence was not seen in the corpuscle even after repetitive stimuli.4) The excitable membrane was not permeable to fluorescent dyes because any Pacinian corpuscle couldn't elicite the fluorescence by means of dyes which were directly applied in the outer solution.5) Ameba proteus also couldn't elicite the fluorescence at 0.002% to 0.1% concentration of ANS when the cell membrane was sustained normality. As soon as the membrane was broken the protoplasma fluorescenced a light green color.


Semiconductor laser travelling wave amplifiers (TWAs) are attractive for terabit telecommunication systems for several reasons. They show strong, fast nonlinear optical behaviour. In addition they are compact, current controlled have high gain, and are waveguided thereby providing a highly efficient nonlinear optical element in situations where linear amplification is necessary, TWAs have now been superseded by erbium doped fibre amplifiers (EDFAs). However, the devices have great potential for applications such as fast switching, phase conjugation, dispersion compensation and frequency conversion. At Imperial College we are investigating the use of multiwave mixing in a TWA and control of the interaction via coherent current modulation. The aim is to use current modulation to enhance frequency conversion.


Purpose This study aimed to report on cancer incidence and mortality for the year 2017 in Korea in order to estimate the nation's current cancer burden. Materials and Methods Cancer incidence data from 1999 to 2014 were obtained from the Korea National Cancer Incidence Database, and cancer mortality data from 1993 to 2015 were acquired from Statistics Korea. Cancer incidence and mortality were projected by fitting a linear regression model to observe age-specific cancer rates against observed years, and then multiplying the projected age-specific rates by the age-specific population. The Joinpoint regression model was used to determine at which year the linear trend changed significantly; we only used data of the latest trend. Results A total of 221,143 new cancer cases and 80,268 cancer deaths are expected to occur in Korea in 2017. The most common cancer sites are the colorectum, stomach, lung, thyroid, and breast. These five cancers represent half of the overall burden of cancer in Korea. For mortality, the most common sites are the lung, liver, colorectal, stomach, and pancreas. Conclusion The incidence rate of all cancers in Korea appears to have decreased mainly because of a decrease in thyroid cancer. These up-to-date estimates of the cancer burden in Korea could be an important resource for planning and evaluation of cancer-control programs.


This chapter introduces the linkage between economic behaviour and risk regulation policies. Analysis of individual behaviour often reveals the nature of private market failures and provides guidance with respect to the appropriate forms of intervention. However, irrationality in behaviour can also generate the impetus for misguided government policies to the extent that policies are responsive to citizen preferences even when they are irrational.


Reclaimed rubber (RR) from waste tires was introduced as a wood adhesive by blending with epoxidized natural rubber (ENR). To improve the polarity of RR and compatibility with ENR, maleic anhydride (MA) was grafted onto RR chains. Influences of RR and RR-g-MA (maleic anhydride grafted reclaimed rubber) on the adhesion of wood adhesive along with their properties such as crosslinking, mechanical properties, thermal stability, and wettability were studied. It was found that RR and RR-g-MA affect the vulcanization of ENR by increasing crosslink density. Especially, in the case of using RR-g-MA generates a new form of an ester linkage. The higher crosslink density together with the formation of ester linkages results in superior thermal stability by the addition of RR-g-MA. In addition, the incorporation of RR exhibited an increase in the lap shear strength when compared with the pure ENR. This improvement is due to the increased crosslink density because the presence of RR resulted in the enhanced cohesive strength of rubber adhesive. Additionally, the incorporation of RR-g-MA showed higher efficiency to improve the adhesion of rubber adhesive. The addition of RR-g-MA has not only enhanced the cohesive strength of rubber adhesive, but also increased the adhesive strength from the interaction between the hydroxy group in cellulose on the wood surface and the polar functional group (i.e., oxirane rings of ENR, maleic group of RR-g-MA and ester group of ester linkage) of rubber adhesive. Therefore, the cohesive fracture was observed in ENR/RR-g-MA adhesive.
HIGHLIGHTS

The worn-out rubber tire as a mass waste can be utilized to develop effective adhesives
The addition of maleic anhydride grafted reclaimed rubber caused to generate new ester linkage between epoxidized natural rubber chains
The epoxidized natural rubber vulcanizates with maleic anhydride grafted reclaimed rubber showed superior thermal stability
The addition of maleic anhydride grafted reclaimed rubber enhanced the adhesive strength of rubber adhesive from the interaction between hydroxy group in cellulose on the wood surface and the polar functional group of rubber adhesive

GRAPHICAL ABSTRACT


Abstract People fear cancer and its impact more than many other health conditions. Because of this fear, oncology social workers have varying degrees of success enabling patients in their struggle to adapt to the disease and its treatment. Unfortunately, this struggle becomes more difficult when racial and cultural differences exist between workers and their patients. If left unattended, the dilemmas that evolve from these differences can cause considerable damage to effective worker-patient relationships and, ultimately, to treatment outcomes. This article proposes that through the use of culturally competent practice strategies, oncology social workers can support African-American cancer patients better in their struggle to achieve an optimal level of functioning.


The scattering of an electromagnetic time-dependent plane wave by the edge of an impedance wedge is analyzed. Suitable expressions are presented for the surface currents which are induced on the two faces of the wedge. Numerical results are shown for different electrical and geometrical configurations and compared with data available in the literature for the case of a perfectly conducting wedge. >


In distributed software engineering, the role of informal communication is frequently overlooked. Participants simply employ their own ad-hoc methods of informal communication. Consequently such communication is haphazard, irregular, and rarely recorded as part of the project documentation. Thus, a need for tool support to facilitate more systematic informal communication via awareness has been identified. The tool proposed is based on the provision of awareness support that recognizes the complete context of the evolution of software artefacts rather than single events. Peer-to-peer (P2P) networking has been successfully employed to develop various distributed software engineering support tools. However, there are scalability problems inherent in naive P2P networks. To this end a semantic overlay network organization algorithm has been developed and tested in simulation prior to deployment as part of a forthcoming awareness extension to the Eclipse environment. The simulation verified that the self-organization algorithm was suitable for arranging a P2P network but several unexpected behaviors were observed. These included wandering nodes, starved nodes, and local maxima. Each of these problems required modification of the original algorithm design to solve or ameliorate them.


A formula was derived for the probability of neutron scattering due to concentration heterogencities for binary and ternary alloys with hexagonal crystal lattices of the AB and AB/sub 3/ types. Both the long order and the correlation in the replacement of lattice points by various kinds of atoms are taken into consideration. (auth)


An explicit and reasonable definition of the quantum soliton states in optical fibers is given. Based on this definition we construct the quantum soliton states from the exact solution of the quantum nonlinear Schr\"odinger equation. The dispersion effect of the quantum soliton is also exactly analyzed.


In this paper we examine methods and algorithms for visualizing three-dimensional non-Euclidean spherical and elliptical spaces with a first-person view, from insider's perspective: we propose an algorithm for implementing camera controls in such spaces, address an approach to visualizing properties of such spaces based on matrix and vector operations which enables us to perform some of the computations necessary for the visualization on GPUs using graphics APIs, describe an implementation of fog effects in such spaces for the purpose of simplifying navigation in them. An implementation of these approaches and algorithms that is intended for visualizing dynamic scenes in such spaces is presented.


In this article, we analyze if and how different levels of government off-load clients onto other welfare state programs that are not under their financial responsibility. We hypothesize that the extent to which cost-shifting takes place in a multitiered welfare state depends on the degree of fiscal centralization, and we expect cost-shifting to be more prevalent in federal countries where the constituent units have strong fiscal autonomy. In order to empirically examine this claim, we compare Germany and Switzerland, two federal countries that differ considerably in matters of fiscal centralization. Empirically, we find that in fact cost-shifting occurred irrespective of the degree of fiscal centralization. However, there are differences in how the two countries reacted to cost-shifting practices. Fiscally centralized Germany has been more successful in limiting cost-shifting practices than decentralized Switzerland. By connecting the literature on social policy and fiscal federalism, the article contributes to a broader understanding of the functioning of multitiered welfare states.


In this paper we review the history and development of bowfishing, provide a case study of a high-profile bowfishing tournament in Oklahoma, survey and summarize management of the sport in all 50 states, and provide scientifically-based approaches for its management. Bowfishing has a distinct niche in the evolution of the bow and arrow and in fishing, as one of several methods practiced by many and scattered indigenous cultures worldwide. In the past century, advances in technology, including the development of the compound bow, custom boat and lighting systems for night bowfishing, and improved information transfer have opened the sport to many people previously unable to participate in the sport at a satisfying level. Bowfishing poses some distinct challenges for fisheries managers compared to angling, including the impracticality of catch-and-release, non-catch (wounding) mortality, and by-catch mortality of non-targeted native species. In 2019, we conducted a survey of 50 state fish and wildlife agencies that indicated only nine states had bowfishing education programs and none had articulated management goals or plans specific to the sport. Evidence indicates that bowfishing may provide plentiful opportunities for harvesting nuisance invasive species such as Asian carps (Cyprinidae) and the Common Carp Cyprinus carpio, but must be practiced much more judiciously, and in some instances, not at all, depending on locality, for higher valued native species such as buffalofishes (Catostomidae: Ictiobus spp.), Paddlefish Polyodon spathula, gars (Lepisosteidae), and rays (Batoidea). Whereas in the terrestrial and avian species that bowhunters most commonly target, males reach a larger size than females, in fish species targeted by bowfishers, the opposite is the case. The result is selective depletion of large, older, mature females and evolutionarily disruptive truncation of life histories. We suggest ten of many potential topics for consideration in agency management planning for bowfisheries. We seek to provide agencies information for developing historical, ecological, and socioeconomic perspectives for managing bowfisheries, as other fisheries, as instruments of species conservation, public benefit, and sound long-term public policy.


Objective To study the influence of different anesthesia selection for senile total hip arthroplasty on postoperative cognition function,and to supply the information of howto select the anesthesia for senile total hip arthroplasty.Methods 36 patiens were divided into two groups:group A were treated with EA,and group B were treated with GA.The MMS of patients were evaluated one day before operation,the first day and the seventh day after operation.Results There was no significant differences in the operation time and mass of transfusion between two groups.The MMS was significantly different between two groups in the first day and the seventh day after operation.The ratio of POCD in the third day after operation was 17%(three in eighteen) in groups A and 22%(four in eight) in group B,there was significant differences between two groups(P 0.05).The ratio of POCD in the nighty day after operation was 6 % in groups Aand 17% in group B,there was significant difference between two groups also.Conclution The influence of GAis bigger than that of EAfor senile total hip arthroplasty on postoperative cognition function


An optical chemical sensing film based on immobilizing of 1,1′diethyl 2,2′-cyanine (pseudocyanine iodide) in nafion film was developed for the determination of Fe(III). The sensing film was homogeneous, transparent, and mech anically stable. Decrease of the absorbance measured at 518 nm was o bserved when the sensing film was immersed in a solution of Fe(I II). The optimum response of the sensing film to Fe(III) was obtaine d in a solution with pH 4.0. Linear calibration curve over an Fe(III) co n entration range of 1-30 ppm with a limit of detection of 0.71 ppm w as obtained. Cd(II) is the major interference. The sensing film exhibited good stability for 2 months and high reproducibility. Th e proposed method was applied for the determination of Fe(III) in wat er samples with satisfactory results. Keywords—iron(III),_nafion, optical sensing film, pseudocyanine iodide


This paper has probed into the view with traditional regional politics of Hunan in terms of the culture of Huxiang. From geographical postition of Hunan, the culture of Huxiang's characteristic and its passing, the paper analyzes Hunan regional politics traditional forming, scale of the politicians' colony of Hunan of each periods, characteristic and so on. At last, by the case of Hunan personage Mao Zedong, it proves further the influence of Huxiang culture on traditional regional politics of Hunan.


Evolutionary computation can increase the speed and accuracy of pattern recognition in multispectral images, for example, in automatic target tracking. The first method treats the clustering process. It determines a cluster of pixels around specified reference pixels so that the entire cluster is increasingly representative of the search object. An initial population (of clusters) evolves into populations of new clusters, with each cluster having an assigned fitness score. This population undergoes iterative mutation and selection. Mutation operators alter both the pixel cluster set cardinality and composition. Several stopping criteria can be applied to terminate the evolution. An advantage of this evolutionary cluster formulation is that the resulting cluster may have an arbitrary shape so that it most nearly fits the search pattern. The second algorithm automates the selection of features (the center-frequency and the bandwidth) for each population member. For each pixel in the image and for each population member, the Mahalanobis distance to the reference set is calculated and a decision is made whether or not this pixel belongs to a target. The sum of correct and false decisions defines a Receiver Operating Curve, which is used to measure the fitness of a population member. Based on this fitness, the algorithm decides which population members to use as parents for the next iteration.


The heat pump market in the UK has grown rapidly over the last few years. Performance analyses of vertical ground-loop heat exchanger configurations have been widely carried out using both numerical modelling and experiments. However, research findings and design recommendations on horizontal slinky-loop and vertical slinky-loop heat exchangers are far fewer compared with those for vertical ground-loop heat exchanger configurations, especially where the long-term operation of the systems is concerned. The paper presents the results obtained from a numerical simulation for the horizontal slinky-loop and vertical slinky-loop heat exchangers of a ground-source heat pump system. A three-dimensional numerical heat transfer model was developed to study the thermal performance of various heat exchanger configurations. The influence of the loop pitch (loop spacing) and the depth of a vertical slinky-loop installation were investigated and the thermal performance and excavation work required for the horizontal and vertical slinky-loop heat exchangers were compared. The influence of the installation depth for vertical slinky-loop configurations was also investigated. The results of this study show that the influence of the installation depth of the vertical slinky-loop heat exchanger on the thermal performance of the system is small. The maximum difference in the thermal performance between the vertical and horizontal slinky-loop heat exchangers with the same loop diameter and loop pitch is less than 5%.


Polycarbosilane and polysilazane, precursors of SiC and Si 3 N 4 , have been incorporated into the binder system for injection-molded Si 3 N 4 -based parts. Property requirements for these precursors as the injection-molding binder are briefly described. The binder removal mechanism is proposed and discussed based on the experimental results. Instead, the gas diffusion effect, rather than fluid wicking, is a key factor. Controlling the thermal decomposition rate of the binder is the key for achieving crack-free dense sintered parts.


The study is undertaken in the framework of the European Leadership in Cultural, Science and
Innovation Diplomacy (EL-CSID) project. This project has the ambition to codify and articulate the
relevance of cultural, science and innovation diplomacy for EU external relations as part of a
systematic and strategic approach. It aims to identify how the Union and its member states might
collectively and individually develop a good institutional and strategic policy environment for extraregional
culture and science diplomacy.
The overarching objectives of this project are threefold:
1. To detail and analyse the manner in which the EU operates in the domains of cultural and
science diplomacy in the current era; comparing its bilateral and multilateral cultural and
science ties with other states, regions, and public and private international organisations.
2. To examine the degree to which cultural, science and innovation diplomacy can enhance the
interests of the EU in the contemporary world order and specifically, to identify:
a) How cultural and science diplomacy can contribute to Europe's standing as an
international actor;
b) Opportunities offered by enhanced coordination and collaboration amongst the EU, its
members and their extra-European partners;
c) Constraints, both existing and evolving, posed by economic and socio-political factors
affecting the operating environments of both science and cultural diplomacy.
3. To identify a series of mechanisms/platforms to raise awareness among relevant
stakeholders of the importance of science and culture as vehicles for enhancing the EU's
external relations. The research generates both scholarly work and policy-oriented output,
which is disseminated through an extensive and targeted dissemination programme.


The following contents are the results from the examination of unisex, fetishism, minimal, and active which are Mods look. Unisex-because of the changing in musician and the role of sex, Mods girl adopted much from men`s clothing The unisex mods look expressed in the 1990s is not the expression confronting the established value and the confusion of sex as it did in the `60s. but possibly the appearance of a fashion trend. Fetishism-In the `60s, the Mods look changed mens clothing into more woman-like clothing which expressed their internal and external values of thinking. This fetishism phenomenon is also strongly expressed among the in the 1990s. This gives a future-orientid feeling by expressing with a modern sense the 60`s fetish dress which used woman-like silhouettes, bright and stretch fabric, colorful and vivid tone. Minimal-The 60s`Mods put on mini skirts called the revolution of length as a mode of resistance and minimal dress as a way of expressing, the liberation of body and the consciousness of beauty. Minimal is reflected well on slim and fit jackets and pants, and short and fit pants etc. Mods look in the `90s also consists of the general trend of slim and fit silhouette. Active-Mods that reject the value of established generation in the 60s showed a sporty and casual trend on fashion. Mods works around clubs wore polo shirts and cadigan, and Mods enjoys scooter often wore anorak parkas. This active style of Mods approched to the young`casual with freshness, expressing newly in the `90s. polo shirts took a seat as an item of street fashion especially in the beginning of 1996. Mods in the 1960s shows well a fashion flow of the age as a street fashion which expresses the mental world reflected in politics, economics, society and culture within the people of the age. These Mods looks revived in the early 1990s awaken an importance of the culture of the young as the cultural qualities included in Mods of the past life and this fashion trend expected to take a part as a symbol of fashion culture.


Because the digital control processing is done in the situation of human-computer interaction,sure to master the basic principles of the tool selected in programming duties,full programming unique place,thinking about the problem of digital control processing can accurately pick knife tool.


[Objective] Bacterium YT1305-1 was isolated and identified from biofouling biofilms. As one of the dominant bacteria in biofouling biofilms, metabolites of bacterium YT1305-1 were investigated. [Methods] 16 S rRNA gene analysis, phylogenetic tree analysis and physiological and biochemical characteristics were carried on to identify the targeted bacterium. Chemical constituents of the bacterial metabolites were purified through silica column chromatography and identified using nuclear magnetic resonance(NMR). [Results] There existed dominant bacterial species in biofouling biofilms. Pseudoalteromonas sp. was identified as one of the dominant species in biofouling bacteria. 16 S rRNA analysis showed P. issachenkonii was one the dominant bacterium. The targeted bacterium was named Pseudoalteromonas issachenkonii YT1305-1 and 10 chemicals were identified from its fermentation broth, including 5 Diketopiperazines(DKPs): cyclo(Gly-Ala)(1), cyclo(Pro-Gly)(2), cyclo(Pro-Tyr)(3), cyclo(Leu-4-hydroxyl-Pro)(4), cyclo(Ala-4-hydroxyl-Pro)(5) and uracil(6), thymine(7), thymidine(8), bis(2-ethylhexyl) adipate(9), phthalate esters(2-ethyl caproic)(10). [Conclusion] There existed bacterial species that were obviously dominant in quantitative terms in biofouling bioflims. Bacterium YT1305-1 was purified as one of the dominant bacterium. Analysis on its metabolites identified several DKPs, which might influence the formation of biofilms and further the development of biofouling. This investigation provides material basis for biofouling studies.


This research focused on seismic performance evaluation of earthquake resistant simple landed house using Confined Masonry (CM) structural system which follows technical specifications set forth in regulation of Appendix 2 of Peraturan Menteri Pekerjaan Umum dan Perumahan Rakyat (Permen PUPR) Nomor 5 tahun 2016 (Permen PUPR No. 5 of 2016). The seismic performance evaluation of the structure is performed by conducting strength based analysis using earthquake loading as specified in SNI 1726:2019. Seismic performance evaluation of Unreinforced Masonry (URM) simple landed house was also performed to be compared. Evaluation result shows that CM house prototype which follows the regulation has good seismic performance. Meanwhile, URM house prototype is inadequate to resist earthquake loads particularly on many locations in Indonesia with moderate to high level of seismicity.


Aim. Of the study was to investigate the influence of renal function, measured by the glomerular filtration rate on long-term outcomes of patients with acute myocardial infarction undergoing percutaneous coronary intervention. Material and methods. This retrospective study included 179 patients who were admitted to hospitals north-eastern district of Moscow with acute myocardial infarction (AMI). Patients were divided into two groups: 1) eGFR ≥ 60 mL/ min/1,73m2; 2) eGFR < 59 mL/min/1,73m2. The cutpoint was death and complications during hospitalization and followup. The mean follow-up period was 18 months. Results and discussion. The 2nd group demonstrated a significantly greater comorbidity. Stenosis of the left main coronary artery (LCA) > 50% was an independent risk factor for death (p=0,021). The mortality rate during follow-up in the 2nd group was significantly higher than the 1st group (p=0,001). Undergoing PCI in patients of the 2nd group was a significantly better long-term survival compared with conservative treatment strategy (Log-rank test = 0,002). Conclusion. Tactics of early PCI compared with conservative tactics of AMI patients with low GFR contributes to better survival.


The Milky Way's Galactic Center harbors a gamma-ray excess that is a candidate signal of annihilating dark matter. Dwarf galaxies remain predominantly dark in their expected commensu-rate emission. In this work we quantify the degree of consistency between these two observations through a joint likelihood analysis. In doing so we incorporate Milky Way dark matter halo profile uncertainties, as well as an accounting of diffuse gamma-ray emission uncertainties in dark matter annihilation models for the Galactic Center Extended gamma-ray excess (GCE) detected by the Fermi Gamma-Ray Space Telescope . The preferred range of annihilation rates and masses expands when including these unknowns. Even so, using two recent determinations of the Milky Way halo's local density leave the GCE preferred region of single-channel dark matter annihilation models to be in strong tension with annihilation searches in combined dwarf galaxy analyses. A third, higher Milky Way density determination, alleviates this tension. Our joint likelihood analysis allows us to quantify this inconsistency. We provide a set of tools for testing dark matter annihilation models' consistency within this combined dataset. As an example, we test a representative inverse Compton sourced self-interacting dark matter model, which is consistent with both the GCE and dwarfs.


Modern society produces vast amounts of digital data related to multiple domains of our lives. We produce data in our free time when browsing the net or taking photos with various personal devices, such as phones or ipads. Businesses and governments also gather a lot of information related to our interests, habits or otherwise personal information (legal status, health data, etc.). The amount of data produced is growning too large for us to be handled manually, and so to assist the user, specialized information retrieval systems have been developed to allow efficient perusal of different types of data. Unfortunately, as using such systems often requires expert understanding of the domain in question, many users get lost in their attempt to navigate the search space. This problem will only be exacerbated in the future, as the amount of data keeps growing, giving us less time to learn about the domains involved. Exploratory search is a field of research that studies user behaviour in situations, where users have little familiarity with the search domain, or have not yet decided exactly what their search goal is. Situations such as these arise when the user wishes to explore what is available, or is otherwise synthesizing or investigating the data. To assist the user in exploratory search and in finding relevant information, various methodologies may be employed, such as user modeling techniques or novel interfaces and data visualization techniques.


The cryopreservation of red blood cells (RBCs) is very important to modern medicine. Cryoprotectants (CPAs) such as dimethyl sulfoxide (DMSO), proline, trehalose, and polyvinyl alcohol (PVA) have been used in the cryopreservation of RBCs, but the results are not satisfactory. Marinomonas primoryensis antifreeze protein (MpAFP) is a Ca-dependent AFP derived from Antarctic bacteria, which can prevent bacteria from freezing under extremely cold conditions and may be suitable for cryopreservation of RBCs. The active region of MpAFP is located in region IV and is called MPAFP_RIV. In this paper, the gene of region IV of MpAFP is introduced into BL21 (DE3) competent cells, and MpAFP_RIV is obtained after culture, separation, and purification. The improved splat assay is proposed, and this method first proves that MpAFP_RIV has strong ice recrystallization inhibition (IRI) activity without Ca. The improved splat assay is easier to operate and lower the cost compared to the traditional one, and the results are consistent with the classic sucrose sandwich assay, proving that this method can accurately detect IRI activity. The feasibility of MPAFP_RIV combined with classical CPA for cryopreservation of RBCs and the methods to increase the yield of MPAFP_RIV are proposed.


Background and Aim: Salmonella species is one of the important pathogens causing food poisoning and gastroenteritis. The aim of the present study was to assess the quality of traditional creams as regards bacterial contamination. Materials and Methods: This was a cross-sectional study including a total of 250 traditional cream and 50 pasteurized cream samples collected in the south of Tehran retail shops. The samples were diluted in a phosphate-buffered saline, transferred to a rappaport-vassiliadis salmonella (rvs) enrichment broth according to the CDC procedures and incubated at 37° C in Hektoen enteric agar and bismuth sulfite agar media for 24 hours. Antimicrobial susceptibility testing was done using the Clinical and Laboratory Standards Institute (CLSI) procedures. On the following day the suspected colonies were examined for phenotype and finally confirmed by the API 20 E test. Results: Of the 250 unpasteurized cream samples 15 (6%) were contaminated with Salmonella. Of the 7 serotypes identified, the most frequent Salmonella serotype was the infantis serotype with 7 cases (33.3%). Furthermore, Coliform bacteria such as Escherichia coli, Enterobacter, Klebsiella and Citrobacter were also isolated. The highest antibiotic resistance was to nalidixic acid (93.3%), tetracycline (73.3%) and trimethoprim (66.7%). None of the pasteurized cream samples was contaminated with Salmonella. Conclusion: The results confirm the need for more effective control and monitoring of the traditionally prepared cream marketed in the city by the Food Control Authority. In addition, educating the public about the consumption of pasteurized cream can play a good role in reducing foodborne illnesses.


Type of funding sources: None.

 CRH in patients with ischemic heart disease is recommended by the different clinical practice guidelines with an IA level of evidence, with an important role in reducing cardiovascular mortality and hospital readmissions during follow-up.

 The goal of this study is to show the 4-year clinical results of a population of patients who participated in an CRH program after an Acute Coronary Syndrome (ACS).

 Between May/2014 and September/2017, 221 patients who had recently presented an ACS completed the 12 weeks of phase II of the CRH program at our center. In May/2020 we collected epidemiological, clinical and echocardiographic information at the time of the acute cardiovascular event; and we evaluate the current vital status of the patients and the incidence of readmissions for: angina, HF, new ACS, or arrhythmic events.

 Of the 221 patients, 182 were men (82%). The mean age of our population was 58.3 ± 7.8 years. 58% (129 patients) suffered from ST-elevation ACS. The mean time of hospital stay was 6.20 ± 2.9 days. An echocardiogram was performed at discharge, which showed an average LVEF of 56 ± 6%. Eight patients (4%) developed early Ventricular Fibrilation (VF) during the acute phase of ACS. Among the classic CVRF, smoking (79%) was the most prevalent, followed by dyslipidemia (53%) and hypertension (47%). The mean time from hospital discharge to the start of phase II RHC was 42 ± 16 days. The overall incidence of events was 9%: 10 patients suffered reinfarction during follow-up, and 7 were readmitted for unstable angina, all of whom underwent PCI; no patient was admitted for HF; and none of the 8 patients with early VF had a new tachyarrhythmia, registering a single admission for VT during follow-up. None of the patients had sustained ventricular tachyarrhythmias during exercise-training. At the mean 4.5-year follow-up, 218 patients were still alive (98%).

 The incidence of CV events in the follow-up of our cohort was low, which can be explained by the fact that it is a young population, with an LVEF at low limits of normality at discharge, which is one of the most important predictors in the prognosis after an ischemic event. As an improvement, we must shorten the time until the start of phase II of the program. CRH shows once again its clinical benefit after an ACS, in consonance with the existing evidence.
 Abstract Figure. Outcomes of a CRH program.


The study aimed to examine Staff Development Policies cum Funding as determinants of Principals' Management Efficiency in public secondary schools in Calabar Zone of Cross River State, Nigeria. Two objectives, research questions, and hypotheses were formulated to guide the study and the study adopted the descriptive survey research design. The population of the study comprised all the five hundred and two (502) principals in public schools in Calabar education zone of Cross River State, Nigeria. To select the required respondents for the study, stratified random sampling techniques were used and the study utilize the Taro Yamane sample size determination to select a sample of 251 (10%) from the population as a sample. A researcher developed an instrument entitled "Staff Development Policies cum Funding and Principals Management Efficiency Questionnaire (SDPFPMEQ). The researcher developed an instrument that was validated by three (3) experts, one (1) in Measurement and Evaluation and two (2) in Educational Management. The reliability of the instrument was estimated with Cronbach Alpha reliability and the index ranges from .93 and .98, implying that the instrument was valid for data collection. The data were analysed with simple regression analysis and the findings revealed that; staff development policy, as well as the funding system, significantly predict Principals' Management Efficiency. It was recommended among others that adequate funds should be provided for the proper management of the departments.


Peruvian Governance Good Corporate Governance is basically an effort to make GCG a rule and guideline for Company managers in carrying out their business activities. The purpose of this study is to find out, analyze and describe the implementation of the principles of Good Corporate Governance at PT Pertamina (Persero). This research uses a qualitative approach with a descriptive method. The method of data collection is carried out by interviews, observations and documentation. The theory used in this study uses the theory of the basic principles of Good Corporate Governance in Hamdani's book (Review of Ethics in Business Practice), namely the principles of transparency, accountability, responsibility, independency and Fairness. The results of this study show that the implementation of the principles of good corporate governance has been implemented by PT Pertamina Persero properly even though it has not been maximized. This is evidenced by transparency with the existence of an official website that can be accessed at any time, as well as clarity in decision making, annual reports, financial reports, and recruitment processes.


Objective
To investigate the mRNA espression level of Caspase-1 and Caspase-3 in the patients with systemic lupus erythematosus(SLE) and its association with lymphocyte apoptosis.

Methods
Reverse transcription-polymerase reaction (RT-PCR) technique was applied to semiquantitatively analyze the mRNA expression of Caspase-1 and Caspase-3 in the peripheral blood mononuclear cells (PBMC) from 34 active SLE patients and 30 healthy subjects.

Results

Conclusion
To investigate the mRNA espression level of Caspase-1 and Caspase-3 in the patients with systemic lupus erythematosus(SLE) and its association with lymphocyte apoptosis. Methods Reverse transcription-polymerase reaction (RT-PCR) technique was applied to semiquantitatively analyze the mRNA expression of Caspase-1 and Caspase-3 in the peripheral blood mononuclear cells (PBMC) from 34 active SLE patients and 30 healthy subjects. Results Compared with normal controls, the mean levels of Caspase-1 or Caspase-3 mRNA expression in active SLE group was significantly increased(P 0.05). Conclusion There are increased expressin of Caspase-1 and Caspase-3 in the PBMC of SLE patients, which may be involved in the lymphocyte apoptosis of SLE patients.

Key words:
Lupus erythematosus, systemic; Caspase 1; Caspase 3; Apoptosis


The sieve method of calulation prime number is improved and spreaded for sieve method of stage, which extends range of calulation, raises speed of moving, and calculates prime number and prime number couple under 200 billions .


Jennifer clancy, a water pioneer in her own right, spoke with five women who have forged paths of career success and influence in the water community.


This study was aimed at developing a membrane system to reuse the waste salt water generated from the Kimchi processing factory. For the best quilted of the pretreatment process, micro filter and bag filter was compared. The case of micro filter showed 14.3% lawer pressure change as compare to that of the bag filter. Micro filter was tested to investigate the effect of the pore size of the pretreatment filter. The flux with 1μm micro filter showed approx. 15% higher than 10μ m one. It than was concluded that 10μm micro filter is more suitable for reuse of the wasye salt water than 1μm one.


The quality and success of engineering studies are decisively influenced (besides other factors) by the teachers' personalities and competences. An engineer should not be just technically adept and broadly knowledgeable, professionally nimble, flexible, and mobile, but he should be also a lifelong learner and a culturally aware intellectual. In our paper we would like to introduce the International Society for Engineering Pedagogy IGIP which is specialized in technical teacher preparation. Other tasks of IGIP are promotion of a scientific approach to the education in engineering, developping theoretical and practice-oriented curricula that correspond to the needs of engineering students and exercising of appropriate didactics.


Antimony trichloride is an efficient catalyst for the cyclization of 2-amino chalcones to the corresponding 2-aryl-2,3-dihydroquinolin-4(1H)-ones under mild reaction conditions and in almost quantitative yields.


Considerably increased production of cardiac prostanoids and intensified linoleic acid metabolism in the cardiac phospholipids were revealed in physiological myocardial hypertrophy in animals trained by swimming. The formation and secretion of cardiac prostanoids was found to be essentially reduced in pathological myocardial hypertrophy in rats with hereditarily determined arterial hypertension, which is attributed to inhibition of the metabolism of linoleic and linolenic acids in the cardiac phospholipids and to structural and functional disorders in the function of the heart.


The design of the microstrip antenna slot bowtie single array with Coplanar Waveguide (CPW) input has been successfully fabricated that can be operate in the frequencies work on IEEE 801.11 b/g (2400-2485 MHz), to wireless communication needs. The antenna design on Print Circuit Board (PCB) FR4 single array with substrate ɛr = 4.3 and the thick is 1.6 mm ground plane with 111,94 mm × 87,57 mm. The antenna design in etching with FeClO3. Results of measurements of parameters of antenna slot bowtie single array microstrip has got the expected results. Characterization of an antenna that is Voltage Standing Wave Ratio (VSWR), Return Loss (RL), Bandwidth and the impedance using a Vector Network Analyzer. At a frequency of 2.4 GHz antenna design slot bowtie single array microstrip shows the value of VSWR is 1,77 and RL registration -11,21 dB. Whereas the frequency bandwidth of 50 MHz on RL -12,45 dB. Expected to design antennas fabricated on the 2.4 GHz frequency can be applied in communication of wireless with wide bandwidth.


ObjectiveTo study the effects of primary preventive intervention on internet addiction tendency in middle school students. MethodsAccording to the Cognitive-Behavioral Model of Internet addiction,the present study provided 3 weeks intervention for 47 middle school students compared with 48 students as a control group. The knowledge about internet addiction,self esteem and classmate relationship,stress coping strategies were given to the experimental group,and trained them how to apply the knowledge into their lives. Three questionnaires were used to measure self-esteem,the knowledge of internet application and the degree of internet addiction before and after the intervention. ResultsThere was a remarkable difference between experimental group and control group on the knowledge of internet application(14.09±1.58 to 15.54±3.15). ConclusionThe primary preventive intervention was effective,especially in the aspect of the habits of internet use.


Introduction: Routine HIV viral load (VL) monitoring is recommended for patients on antiretroviral therapy, but frequent VL testing, required in pregnant and postpartum women, is often not feasible. Self-reported adherence can be valuable, but little is known about its longitudinal characteristics. Methods: We followed women living with HIV from antiretroviral therapy initiation in pregnancy through 18-month postpartum in Cape Town, South Africa, with repeated measurement of VL and self-reported adherence using a 3-item scale. We used generalized estimating equations [with results presented as odds ratios (ORs) with 95% confidence intervals (CIs)] to investigate the association between viremia and change in adherence over pairs of consecutive visits. Results: Among 2085 visit pairs from 433 women, a decrease in self-reported adherence relative to the previous visit on any of the 3 self-report items, or the combined scale, was associated with VL >50 and >1000 copies per milliliter. The best-performing thresholds to predict VL >50 copies per milliliter were a single-level decrease on the Likert response item "how good a job did you do at taking your HIV medicines in the way that you were supposed to?" (OR 2.08, 95% CI: 1.48 to 2.91), and a decrease equivalent to ≥5 missed doses or a one-level decrease in score on either of 2 Likert items (OR 1.34, 95% CI: 1.06 to 1.69). Conclusions: Longitudinal changes in self-reported adherence can help identify patients with viremia. This approach warrants consideration in settings where frequent VL monitoring or other objective adherence measures are not possible.


Damage detection technology based on wavelet packet energy has been widely applied to structural health monitoring, especially for one-dimensional structures. With more complex vibration characteristics than one-dimensional structure, two-dimensional structure is common in ship structure. It is a challenge for using wavelet packet energy methods to detect damage in two-dimensional structures. In this study, based on the wavelet packet energy eigenvector, a novel concept of detection index ratio (DIR) is defined to characterize the damage location ability of the excitation force. Based on the above research, a multi-excitation method of damage location in plate-like structures is proposed. In this method, a series of half-sine pulse excitation forces with different frequencies are applied to the structure, and wavelet packet transform (WPT) is used to decompose the vibration response of the intact structure and the damaged structure. The energy ratio changes in frequency bands on all measuring points are taken as the preliminary damage detection index, and the final detection index is obtained by synthesizing the preliminary indexes under various excitation. Moreover, to verify the effect of the proposed method, several tested damage cases are presented. The results show that the proposed method can locate single and multiple damage more accurately and has better noise robustness than the traditional detection method under single excitation.


The article describes scientifically-a practical substantiation and the analysis of differentiation of territories sanitary-protective zones of the industrial enterprises; workings out of a method of the organization of the territories of industrial targets taxation. Considered method of the industrial enterprises sanitary-protective zones taxation organization.


Diet and food consumption of a stunted population of Arctic charr in Takvatn, northern Norway, was studied throughout the ice-free season. Chironomid pupae dominated the diet in June, July and August, while zooplankton and three-spined sticklebacks dominated in September and October. Estimates of gastric evacuation rates were obtained from laboratory experiments with wild-caught, acclimated charr, and these estimates were used for in situ estimation of food consumption from weights of stomach contents. The daily food consumption was greatest in July, after which it decreased markedly towards autumn. The estimated food intake rates were low, especially in September and October. The food supply appears to be restricted, which is probably the main reason why the charr in Takvaln exhibit stunted growth.


I this paper, a simulation model of CNC feed-drive's servo-control system, witch could be utilized to design and develop CNC controllers, is presented. A precise model of machine tools components and controller, which we may call virtual machine, is employed as an experimental aid to carry out practical and economical test for verifying command generation modules.


Objective:   Herein, we aimed to determine the diagnostic contribution of ultrasound elastography (UE) technique to the assessment of muscle stiffness in pediatric patients with myositis.
Material and Methods: This study enrolled 16 patients who presented to our hospital's Pediatric Neurology Outpatient Clinic with the complaint of inability to walk and who had a clinical presentation of benign acute childhood myositis (BACM). The patients were referred to the Radiology Department to undergo muscle ultrasonography (USG), where they underwent UE of the gastrocnemius muscle (GCM).
Results: Children with myositis and healthy children are similar age (7.06 ± 1.52 year (5–11) vs. 7.00 ± 1.59 year (5–11) year) (P: 0.908) and body mass index (BMI) (20.04 ± 1.58 (18.6–24.2) vs. 22.08 ± 1.43 (19.9–24.4) (P: 0.946). The mean serum creatine kinase (CK) was measured as 1520.3 ± 1163.6 U/L (min: 456,  max:4100) in children with myositis. In the children with myositis, the thickness of the medial and lateral GCM increased compared with that in control group (medial; 18.15 ± 3.02 mm vs 13.10 ± 2.26 mm, p<0.001, lateral; 13.51 ± 3.07 mm vs 9.34 ± 1.86 mm, p<0.001). The medial and lateral GCM ratio in group 1 was slight bigger than that in group 2 (medial; 1.10 ± 0.37 vs 1.00 ± 0.34, p: 0.274, lateral; 1.22 ± 0.44 vs 1.10 ± 0.29, p: 0.243). GCM strain values were mildly elevated in patients with myositis compared to controls.
Conclusion: In the children with myositis, the thickness of the medial and lateral GCM increased compared with that in control group. GCM strain ratio values were slightly higher in myositis patients compared to the control group. We think that the increase in muscle thickness values is mainly secondary to the edema seen in myositis. In addition, UE is a clinically applicable quantitative analysis for changes in myositis.


The production of $Z^{0}$ bosons in the reaction $eparrow eZ^{0}p^{(*)}$, where $p^{(*)}$ stands for a proton or a low-mass nucleon resonance, has been studied in $ep$ collisions at HERA using the ZEUS detector. The analysis is based on a data sample collected between 1996 and 2007, amounting to 496\, pb$^{-1}$ of integrated luminosity. The $Z^{0}$ was measured in the hadronic decay mode. The elasticity of the events was ensured by a cut on $\eta_{{\rm max}} < 3.0$, where $\eta_{{\rm max}}$ is the maximum pseudorapidity of energy deposits in the calorimeter defined with respect to the proton beam direction. A signal was observed at the $Z^{0}$ mass. The cross section of the reaction $ep arrow eZ^{0}p^{(*)}$ was measured to be $\sigma (ep arrow eZ^{0}p^{(*)}) = {\rm 0.13 \pm{0.06} ({\rm stat.}) \pm{0.01} ({\rm syst.})}\, {\rm pb}$, in agreement with the Standard Model prediction of $0.16\, {\rm pb}$. This is the first measurement of $Z^{0}$ production in $ep$ collisions. In this paper we report the already published ZEUS result by adding the sensitivities of the most recent similar results from CMS and ATLAS.


Sex cord-stromal cells at extraovarian sites are extremely rare and due to the low number of cases reported, the true incidence is unknown. We present the case of a patient with symptomatic uterine fibromas that had a benign extraovarian heterotopic sex cord-stromal proliferation.

 A 44-year-old female presented with pelvic pressure and discomfort. Past medical history is significant for breast cancer treated with bilateral mastectomy in 2019 followed by radiation treatments. The patient had no menses since January 2020 but had begun noticing spotting prior to the onset of her pelvic pressure and discomfort. Pelvic ultrasound revealed an enlarged uterus consistent with fibroids and a right adnexal mass. Endometrial biopsy following the ultrasound was normal. The patient desired definitive treatment and a total abdominal hysterectomy and bilateral salpingo-oophorectomy was subsequently performed. Gross examination of the surgical specimen revealed a fibroid uterus and normal appearing bilateral ovaries and fimbriated fallopian tubes. Histopathology showed a uterus with leiomyomata and serous cystadenofibromas in bilateral ovaries. The left fallopian tube fimbria showed a well-circumscribed proliferation of pale, ovoid cells in a microfollicular pattern. Rare cells with grooved nuclei were present. No significant atypia and no mitotic activity were identified. Immunohistochemical staining was positive for inhibin, WT-1, and vimentin. Negative stains include EMA, GATA-3, GCDFP 15, mammaglobin, chromogranin, and calretinin. Final diagnosis was determined to be benign fallopian tube with heterotopic sex cord-stromal proliferation.

 NA

 This case highlights a rare, incidental finding. These lesions are postulated to represent non-neoplastic embryologic remnants. However, most heterotopic sex cord-stromal proliferations are found in fimbriae, which could suggest that they arise from heterotopic ovarian tissue exposed during ovulation. The incidence of these benign proliferations is expected to increase as routine sampling of adnexal structures is becoming more commonplace, which presents diagnostic challenges for pathologists.


Cost Engineering Basics. Cost Accounting. Cost Estimating. Economic Equivalence and Profitability. Cost Control and Reporting. Project Management and Schedule Control. Cost Indexes, Escalation, and Location Factors. Operations Research Techniques. Risk Analysis: How to Do it and How Not to Do it. Cost Engineering in a Worldwide Economy. Computer Applications for Project Control. Cost Engineering Ethics


With the development of science and technology, grid technology has played an increasingly important role in people's lives. Grid technologies prospects has also been given great expectations. However, due to the platform of grid feature relies the Internet and its characteristics in use will encounter a range of security issues, and as an emerging technology, it also will face a variety of challenges, so the research of the problems of grid security communication becomes practical significance. In this article, it will be focused on security communication of grid services and grid access control, and put forward the own points idea.


We have successfully grown GaN self-assembled quantum dots (QDs) with high density on an AlxGa1–xN surface, by the Stranski-Krastanow growth mode in a metalorganic chemical vapour deposition. An abrupt transition from two-dimensional to three-dimensional growth mode is observed by depositing over the critical thickness of GaN. The density of the QDs can be changed between 109 and 1010 cm–2. Furthermore, intense photoluminescence (PL) peaks from both the QDs and the wetting layer are clearly observed even in the uncapped QD structures at room temperature. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)


Background: Tobacco use is one of the main preventable causes of morbidity and mortality in the world. This report presents the experience of the smoking cessation team from the National Thorax Institute (Instituto Nacional del Torax-Chile). Patients and Method: A clinical series of patients treated between April 2013 and March 2014, with one-year follow-up was studied. Intervention was based on seven group sessions, with a cognitive behavioral viewpoint and pharmacological treatment (mainly varenicline). Follow-up was done through telephone calls at 1, 3, 6 and 12 months. Descriptive statistics and X² test were used. Results: Eighty-seven patients were treated, mean age 54 years, 63% women; 79% had a pack year index over 20; 28% had depression and 16% had COPD. 59% received varenicline. Self-reported abstinence for 12 months was 37%. No significant differences between high risk groups were found. Conclusion: The smoking cessation program done at the National Thorax Institute shows that it is feasible to implement this type of programs in the public health system of Chile with results comparable to those internationally published.


Optimal power flow (OPF) is considered one of the most critical challenges that can substantially impact the sustainable performance of power systems. Solving the OPF problem reduces three essential items: operation costs, transmission losses, and voltage drops. An intelligent controller is needed to adjust the power system's control parameters to solve this problem optimally. However, many constraints must be considered that make the design process of the OPF algorithm exceedingly tricky due to the increased number of limitations and control variables. This paper proposes a multi-objective intelligent control technique based on three different meta-heuristic optimization algorithms: multi-verse optimization (MVO), grasshopper optimization (GOA), and Harris hawks optimization (HHO) to solve the OPF problem. The proposed control techniques were validated by applying them to the IEEE-30 bus system under different operating conditions through MATLAB simulations. The proposed techniques were then compared with the particle swarm optimization (PSO) algorithm, which is very popular in the literature studying how to solving the OPF problem. The obtained results show that the proposed methods are more effective in solving the OPF problem when compared to the commonly used PSO algorithm. The proposed HHO, in particular, shows that it can form a reliable candidate in solving power systems' optimization problems.


A program which vertically packs IGFET logic circuit nodes in the modular Weinberger arrangement will be discussed. Program output can interface directly with artwork generators. Area savings of up to 50% have been obtained.


In 1982 Costa Rica had an infant mortality of 18 per 1000 live births and a life expectancy at birth of 76 years for women and 72 years for men. In the evolution of infant health in Costa Rica two paradigms were identified. One developed in the decades before 1970 and the other during the 1970s. The necessity of conceptualizing a third new paradigm compatible with health needs of the present and the immediate future is recognized. The first or "malnutrition paradigm" was orthodox in its derivation; it identified the lack of food as the underlying base for the major health problems and placed its emphasis on institutional medicine. The paradigm was influenced by foreign schools of nutrition and pediatrics and led to the development of an infrastructure for the delivery of medical services and the programs for food distribution. The "infectious disease paradigm" recognized infectious diseases as the main determinants of morbidity, mortality and malnutrition in childhood. The strategies derived from such a revolutionary paradigm aimed at the control and eradication of infectious diseases, and they resulted in a rapid improvement of child nutrition and health. However, the infectious disease paradigm does not seem to reduce infant mortality below the present level. Thus the "holistic health paradigm" is proposed in which the control and prevention of infectious diseases are maintained but priority is given to the prevention of perinatal problems, noninfectious diseases and various disabilities. This paradigm copes with life styles, individual responsibility and coordination of public and private health and medical care. The paradigm focuses on emerging health problems that in the past were not apparent or were masked by the prevalence of malnutrition and infectious diseases. The dramatic results observed in Costa Rica and in a few other tropical countries show that health can be improved without undergoing urbanization and industrialization. The malnutrition paradigm should be discarded. The infectious disease paradigm should guide public health action in underdeveloped countries to ensure a reduction in malnutrition and infant mortality. The holistic health paradigm is the option for countries like Costa Rica in which a further improvement of present health status no longer depends on control of infectious diseases alone.


We examine, both theoretically and empirically, how the timing of product recalls depends on the quality of information firms have about possible defects, the proactivity of the regulator (NHTSA), and the need to raise external finance. We find evidence that large recalls are timed strategically to minimize the impact of recalls on the cost of external finance. This type of strategic timing of product recalls suggests that, contrary to company statements and some internal investigation reports associated with recent large scale vehicle recalls, top management is typically aware of product defects. JEL Classification Codes: G32, G38


Resilient metallic structural seals are used to seal the secondary airflow regions in air and land based gas turbines. These seals are typically manufactured from thin strips of high temperature cold formable wrought superalloys, including alloy 718, Rene 41, and Waspaloy. Traditional wrought alloy seals exhibited excessive stress relaxation at temperatures above 730°C, which resulted in a loss of sealing integrity and excessive leakage. For applications above 730°C, seals are generally cooled using compressor bleed air which could otherwise be used to generate power. To minimize stress relaxation, an ultra-high temperature seal design incorporating a spring energizer made from cast single crystal turbine blade alloys was pursued. The creep-resistant cast single crystal blade alloy spring inserted in a wrought alloy sealing jacket provided the sealing force, increasing the service temperature of metallic seals to 950°C. This increase in seal performance is expected to reduce or eliminate the need to actively cool seals, improving the fuel efficiency of gas turbines.


SUMMARY This paper presents a sensory gripper, consisting of two tactile sensing matrices which acquire three dimensional images of objects of interest. The image processing algorithm uses elastostatic contact information to discriminate among a host of parts made of different materials. The algorithm also enables the assessment of orientation of parts without the pre-requisite of having to recognise them. The positions of stable holdsites and a safe gripping force are also evaluated.


Cultivated and wild Allium species were investigated in order to compare the antioxidant capacity of their leaves and bulbs. Leaf and bulb anti-oxidative enzymes and scavenger activities, along with quantities of non-enzymic antioxidants, malonyl-dialdehyde and OH radicals were determined. Results obtained suggest that leaves possess higher anti-oxidant and scavenging activities than bulbs in the majority of cultivated and wild Allium species examined. Cultivation of some wild species such as A. flavum L., A. schoenoprasum L. and A. ursinum L. could be conducted in the future in order to produce Allium species with high antioxidant capacity in leaves and bulbs.


28 29 Despite the rapid spread of antibiotic resistance among gonococci worldwide, limited reports 30 are available from Brazilian locations. In the present study, 25 quinolone-resistant N. gonorrhoeae 31 (QRNG) strains isolated in Rio de Janeiro, Brazil, were characterized by phenotypic and molecular 32 methods, including analysis of mutations in the gyrA and parC genes. They represented 16.5% of the 33 N. gonorrhoeae isolates obtained during a survey performed from 2006 to 2010. 34 A trend for increasing resistance to ciprofloxacin was observed in the period investigated. The most 35 prevalent pattern of mutation observed among QRNG isolates, Ser-91 to 95 in gyrA and Asp-87 to 36 Arg in parC, was detected in 40% of the isolates exhibiting MICs ranging from 4 to > 32 μg/ml. Rare 37 types of mutations were found in the gyrA gene : Gln-102 to His (12%); Asp-95 to Tyr (4%) and in 38 parC gene: Ser-88 to Thr (4%). The genetic relationship of the QRNG isolates, evaluated by pulsed39 field gel electrophoresis (PFGE), suggested that the increase in the frequencies of the QRNG isolates 40 in Rio de Janeiro, Brazil, may have arisen as a result of simultaneous spread of two clonal groups. The 41 results also indicate that fluoroquinolones may no longer be used as first line antibiotics for the 42 treatment of gonorrhea in Rio de Janeiro, and that programs for antimicrobial susceptibility 43 surveillance of N. gonorrhoeae should also be implemented in other regions of Brazil. 44 45 46 47 48


This study attempts to evaluate the relationship between tourism and trade and self-employment growth in Ghana, Nigeria and Cote d'Ivoire using a time series data spanning the period 1991-2019. In this study, an applied GMM approach was employed. Results show that export and import trade, development assistance and personal remittance flows significantly spur self-employment during the study period while indicators of tourism activities represented by the number of tourist arrivals retard growth of self-employment but increase export trade in these countries. On this basis, the business atmosphere and infrastructural facilities should be improved to sufficiently boost the relationship between trade and tourism and hence spur self-employment growth in these countries.


This Legal Scholarship Symposia Articles is brought to you for free and open access by TU Law Digital Commons. It has been accepted for inclusion in Tulsa Law Review by an authorized editor of TU Law Digital Commons. For more information, please contact email@example.com. Recommended Citation Robert W. Gordon, Morton Horwitz and His Critics: A Conflict of Narratives, 37 Tulsa L. Rev. 915 (2013).


The road tunnel install a vent for the purpose of ventilation and smoke control. Ventilation equipment capacity(number of jet fans) depends on from the condition that of the pressure and ventilation resistance. Pressure and the resistance under operating vehicle have affected on the drag coefficient. The drag coefficient of the tunnel have affected by the blockage effect and slipstream effects. However, when calculating the ventilation fan, are not properly consider taking into account such effects. Therefore, ventilation force may have been slightly overestimated. This paper describes the drag coefficient through a numerical analysis to calculate the equivalent resistance area that reflects the vehicle distance, and examined the equivalent resistance area. The ventilation coefficient corresponding to the result heavy vehicle mixing ratio of the present study was not clear. Equivalent resistance area had reduced by about 86% compared to the road design handbook current standards. Also it had analyzed and reduced to 62.2% compared to Korea Highway Corporation ventilation design criteria ratio, which is the old standard.


One of the state-of-the-art optimization strategies is the introduction of an artificial neural network in place of a more time-consuming numerical tool to compute the cost function. This work describes the development of a genetic algorithm optimization strategy for a meandered microstrip line by using an artificial neural network whose training set has been designed by a uniform sampling of the global design space. The results in terms of the total radiated electromagnetic power are discussed and compared with those obtained by the initial and not optimized configuration.


Six strains were isolated from Lake Akflehir (Konya-Turkey) and identified as Rhodopseudomonas palustris on the basis of physiological and morphological characteristics. The strains grew phototrophically on a variety of aromatic compounds (under illuminated anaerobic conditions), namely, benzoate, hippurate, benzyl alcohol, 2-amino benzoic acid, phloroglucinol, phenylacetic acid, catechol, pyridine and pyrazoline. Biodegradation of 2-amino benzoate, phloroglucinol, catechol, pyridine and pyrazolin by Rhodopseudomonas palustris strains have not been reported in the literature.


A 72‐year‐old African‐American man with frequent recurrent syncope was found to have severe refractory orihostatic hypotension with concomitant supine hypertension. Pharmacotherupy was successful in controlling his supine hypertension but was unable to resolve his severe orihostatic hypotension. Temporary fixed rate tachypacing was only minimally effective in preventing syncope during upright tilt, while variable rate pacing based on degree of blood pressure fall was far superior. Following these observations, an adaptive rate pacing system controlled by right ventricular preejection interval was implanted (Precept DR Model 1200). The system adequately sensed the patient's fall in blood pressure when sitting or standing and augmented its rate accordingly, thus preventing syncope. While supine, the pacing rate fell to 60 ppm, thereby, avoiding an exacerbation of his concomitant supine hypertension. Over a 3‐nionth follow‐up period, he has had no further orthostatic or syncopal episodes. We conclude that adaptive rate pacing using right ventricular preejection interval may be an effective treatment for severe refractory orthostatic hypotension.


Immunization is a way to increase a person's immunity against a desease, so that when later exposed to the desease he did not because ill. Hepatitis B is a potentially ife-threatening liver invection caused by hepatitis B virus. WHO recommends that all infants receive hepatitis B vaccine immediately after birth, preferably within 24 hours. This research was conducted in Pratama Sehati Husada Deli Tua Medan Clinic Year 2015. This research is descriptive followed by 73 volunteers. The Results of this study showed that the level of knowledge of respondents about hepatitis B O immunization is mostly in the category of suffice, which is 54 people (74%), while the good category is 10 people (13,7%), while the least is in the category of less, with 9 people (12,3%).


Mn-Zn-Co ferrite single crystals with Fe-deficient initial composition, for VTR heads, have been grown by the Bridgman technique under about 1.5 atm. oxygen pressure. From the X-ray diffraction patterns obtained, only spinel phase is observed. The results of chemical analysis show that the distribution of component cations within the crystal is inhomogeneous. The crystal possesses permeability of 1300, 700 and 400 at 5 MHz,10 MHz and 15 MHz respectively and high resistance.


This paper produces a modified Wu-Manber multiple patterns matching algorithm,based on the idea of the Wu-Manber algorithm.The algorithm replaces the Same-subsuffix link used in[4] with two links: Left-subsuffix and Right-subsuffix.So when it comes to comparing the characters in the Same-subsuffix link,what we need to do is compare them in one of the link we used about,and then reduces the amount of characters matching.The new algorithm works particularly well when the patterns number is large.


A method is proposed for implementing the cross-lingual porting of recognition models for rapid prototyping of speech recognisers in new target languages, specifically when the collection of large speech corpora for training would be economically questionable. The paper describes a way to build up a multilingual model which includes the phonetic structure of all the constituent languages, and which can be exploited to interpolate the recognition units of a different language. The CTSU (Classes of Transitory-Stationary Units) approach is exploited to derive a well balanced set of recognition models, as a reasonable trade-off between precision and trainability. The phonemes of the untrained language are then mapped onto the multilingual inventory of recognition units, and the corresponding CTSUs are then obtained. The procedure was tested with a preliminary set of 10 Rumanian speakers starting from an Italian-EnglishSpanish CTSU model. The optimal mapping of the vowel phone set of this language onto the multilingual phone set was obtained by inspecting the F1 and F2 formants of the vowel sounds from two male and female Rumanian speakers, and by comparing them with the values of F1 and F2 of the other three languages. Results in terms of recognition word accuracy measured on a preliminary test set of 10 speakers are reported.


Destruction of the cartilage aggrecan network is a key event in joint pathologies such as osteoarthritis. Aggrecanases, such as ADAMTS-5 (a disintegrin and metalloprotease with thrombospondin repeats 5), are therefore prospective therapeutic targets. To date, the consequences of ADAMTS-5 ablation in cartilage have yet to be investigated at the proteome level. Here we compared interleukin-1a (IL-1a) and retinoic acid (RetA) -induced cartilage degradation in the presence and absence of ADAMTS-5 catalytic activity using WT and TS5Dcat mouse femoral head cartilage explants. Proteins harvested from the media of control and stimulated cartilage were analyzed by nano-LC and tandem mass spectrometry (LTQ-Orbitrap), and MaxQuant/Perseus software used for protein identification and to compare peptide ion intensities between treatments.
We identified 384 proteins based on two or more distinct peptides (protein FDR


This research examines the capabilities and boundaries of a hands-free mobile augmented reality (AR) system for distributed healthcare. We use a developer version of the Google Glass head-mounted display to develop software applications to enable remote connectivity in the healthcare field; characterize system usage, data integration, and data visualization capabilities; and conduct a series of pilot studies involving medical scenarios. This paper presents the software development and experimental design for a pilot study that uses Glass for augmented point-of-view sharing during surgery. The intended impact of this research is to: (i) examine the use of technology for complex problem solving and clinical decision making within interdisciplinary healthcare teams; (ii) study the impact of enhanced visualization and auditory capabilities on team performance; and (iii) explore an AR system's ability to influence behavior change in situations requiring acute decision-making through interaction between centralized experts and point-of-impact delivery personnel. Keywords—ambient; systems; distributed; healthcare; teambased collaboration; head-mounted display, surgery; wearable computing.


Strawberry plants, Fragaria x ananassa D. var. Chandler and Sweet Charlie, they were exposed to different processing with low temperatures: 1) 30 and 60 minutes to 4oC and -2oC and 2) eight days to 4oC and -2oC. Besides, plants of strawberry of the two varieties were acclimated by 15 days to 4oC and subsequently exposed 30 and 60 minutes to -2oC. The enzymatic activities were analyzed peroxidase (POX) and polyphenoloxidase (PFO) and the total content of soluble proteins. Thus same, some electroforetics profiles of proteins were carried out to compare the bosses between the plants control and them exposed to low temperatures. The impact of the thermal stress on the plants of strawberry of the two varieties that were not acclimated caused: 1) decrease of the enzymatic activities peroxidase and polyphenoloxidase and 2) increase in the total content of soluble proteins. These results can indicate that the stress by low temperatures caused the accumulation of phenolics composed, so much by the activation of their biosynthesis as by the inhibition of their oxidation and, that the plants of strawberry accumulated or they synthesized new proteins to protect the cells of the wounds caused by this type of stress. In general, the decrease of the enzymatic activities POX and PFO in the two varieties of strawberry, indicates that these activities are not related to the degree of tolerance that has been reported for each one of them and that do not they do part of the protection constituent mechanism to minimize the cell oxidatives damages caused by the low temperatures. Finally, in the electroforetics profiles of proteins the apparition was shown so much of new proteins in the vegetable weaving exposed to low temperatures as in the plants previously acclimated.


Background: The object of the current study was to evaluate the reduction in volume caused by myolymphokinetic activities associated with the use of a gorgurao sleeve in patients with lymphedema.


Small groups of internationally recognised engineers have a significant, though impartial, advisory role in large infrastructure investment, though not everyone is clear on how to proceed. Condensing the combined experience of nearly half a century, the authors open the discussion by recommending some guidelines for establishing such consulting boards


AbstractThis article argues for the adoption of an immersive-participatory method when analysing interactive media. It builds upon and extends existing theorisations of immersion and applies them to the development of new methods of analysis. This paper theorises immersion during gameplay as an affective, embodied state, which is both active and passive and achieved via both visual and imaginative engagement with the game world and haptic communication with the player character. This article's argument is fourfold: firstly, it situates and negotiates the tensions surrounding the major debates, discussions and analyses in the study of immersion, both within gaming and in wider contexts; secondly, it argues for the inclusion of a participatory immersive method to be undertaken by the researcher when analysing media (especially interactive media such as video games); thirdly, it outlines the ways in which this method could be implemented by researchers, and finally, it draws on examples from my own research journal and discusses the possibility of a moral habitus which allows the player to engage in violent gameplay without experiencing the moral dissonance that can disrupt immersive states. Ultimately, this article aims to render the position of the researcher visible in order that we might gain critical purchase on the immersive praxis of gaming and the ethical/political responses of the player. In so doing, it is hoped that this article will aid theoretical and methodological innovation in this field and provoke discussion in a wider media studies context.KeywordsImmersion, interactive media, reflexivity, autoethnography, ethical response, habitusA number of researchers of videogames have posited that the main difficulty facing games scholars is not why we should study them, but how (Mayra, 2008: p.2-3; Buckingham, 2008: p.1). Application of theories from other disciplines is both useful and insightful, but many debates within the field have centred on whether this approach is sufficient in and of itself. As videogames are demonstrably both visual and audial, as well as, at least in part, structured around narrative, it would seem that videogame researchers cannot ignore the scholarship which exists in fields such as media studies, literature studies, and sociology. Beyond this evaluation, however, the videogame must be recognised as a medium distinct from literature and film due to the rules which define and restrict interactive play. As these rules impact upon other elements of the game (such as narrative), the rule set which governs gameplay must therefore be analysed alongside the other visual, audial, temporal, social, and experiential elements of a game in order to give a fair and full analysis.If we consider both the significant expenditure of time and effort needed to play videogames, it seems a commonsensical view that they have the potential for significant cultural and social impact on players. While this view needs to be investigated and supported, especially as it is a background assumption for the moral panic which has fuelled media debates around the effects of violent games (see for example Pow, 2012; Daily Mail, 2012), it is nevertheless useful to consider the interactions and perceived engagements which form the basis of gaming praxis and which have led people to make these assumptions. For many narrative-led AAA ("triple A") games (which are the focus of my research) in order to play the game to completion, whether simply beating the game or actually aiming for a 100% achievement rating, the time spent immersed in the gameworld often totals tens if not hundreds of hours.2 This time is not spent on a passive process; not only because videogames require active involvement on some level in order to function and progress, but also because there is a necessary process of "internalising" the controls and active problem-solving involved. To "beat" a game, therefore, some level of involvement, both physical and psychic, on the part of the player is necessary. …


The distance coloring number Xd(G) of a graph G is the minimum number n such that every vertex of G can be assigned a natural number m ≤ n and no two vertices at distance i are both assigned i. It is proved that for any natural number n there exists a graph G with Xd(G) = n.


—With Ascon being selected as the new NIST lightweight cryptography standard, it is imperative to study how it lends itself to different use-cases that may not be covered directly by the original proposal. In this abstract, we focus on Message Authentication Codes (MACs). We study six ways of instantiating MACs using the Ascon permutations (Ascon-p). We compare these methods over multiple metrics, including throughput, hardware utilization, security margins/claims, side-channel friendliness and energy consumption of short and long messages. The comparison is performed with Xilinx Artix-7 FPGA as a target.


We read with great interest the article by Curtis et al on etanercept or methotrexate withdrawal in rheumatoid arthritis. They have taken patients in sustained and deep remission- fulfilling the stringent Simplified Disease Activity Index (SDAI) criteria and simulated near-ideal conditions, before withdrawing either methotrexate or etanercept from the regimen. They have then observed the proportion of patients who maintained SDAI remission at week 48.


⎯ The availability of onshore wind power plant systems (PLTB) reaches 98%, but the maintenance costs required are still very high for the wind turbine system. Meanwhile, the availability of offshore PLTB is decreased by 60% due to the main cause of damage to some components in wind turbine systems. This study proposes the use of fault estimation methods of sensor and actuator in fault tolerant control (FTC) strategy, especially in Wind Turbine. The fault estimation method is build using the ℓ 0 norm constraint optimization. The optimization formulation with ℓ 0 norm constraint is derived by applying the compressed sensing technique so that the estimation of the bias error can be used to estimate the fault of several components by a single observer. This answers the observability issues encountered in single observer use cases. The proposed implementation of observers with the FTC results in better response characteristics when compared to systems without FTC. Response characteristics on actuator fault of 0.3 – 1.3pu, system with observers resulting in a maximum undershoot value of 0.4-1% while systems without observers resulting in a maximum undershoot value of 6.2-26.4%. The characteristics of the response with the observer on sensor fault resulting 0.3-1.3pu resulting in value of 1.6-4%, 0% and 63.9- 70.7s. System without observers, with sensor fault of 0.3-1.3pu resulting in maximum undershoot, steady state error and settling time of 6.2-26.2%, 6.2-26.4%, and 0s


case ofa 42year oldhomosexual man withmastitis oftheleftbreastdue to Neisseria gonorrhoeae ispresented on account ofitsextreme rarity. Itwas probablyacquired as a result ofdirect oral-nipple contact. (Genitourin Med1993;69:222-223)


This work describes a top level architecture for a general cryptographic process targeting FPGA. This architecture can be implemented for any crypto system, a symmetric or asymmetric process. The architecture allows pipeline implementation on operations. The results measured with Elliptic Curve Cryptography (ECC) presents that this architecture is efficient in FPGA technology and is an option focusing the future demand.


Recently, President Trump correctly described health care policy making as "unbelievably complex"— although his comment that "nobody knew that" must have been a surprise to the many analysts and lawmakers who for decades have worked on health care reform. Health care policy making is technically complex, of course. But it is also complex in that the president and Republicans seeking to replace the Affordable Care Act (ACA) face very difficult political and philosophical choices. It was evident from the internal backlash to the recent Republican House committee bills that there is a deep divide among Republicans on these choices. Consider 3 such tough issues: deciding what coverage means, making hard choices about subsidies, and determining how to cover people with chronic illnesses.


Takeing the jujube orchard intercropping cotton as experimental material In southern Xinjiang to study the influences of different irrigation water on spatial distribution of cotton bolls and yields. Setting the moderate water stress W1 (250 m3/667m2), mild water stress W2(300 m3/667m2), the appropriate moisture W3(350 m3/667m2), the sufficient water supply W4(400 m3/667m2), in total four different irrigation water processing. The results show that : (1) The cotton boll' shedding rate in different water processing in order W4 > W1 > W3 > W2,the shedding rate of upper and lower is much higher than the middle fruit spur.(2)the effective boll of cotton are mainly in the middle part. (3)The total boll weight of cotton middle fruit spur greater than the total boll weight of fruit spur in the upper and lower. And the lower part' weight is slightly higher than the upper.(4) The boll weight of upper fruit spur have bigger fluctuations than the lower,each part of the cotton boll weight as W2 > W3 > W4 > W1. (5) Four water treatment have a little effect on lint percent, seed cotton and ginned cotton showed the same trend as W2 > W3 > W4 > W1. Comprehensive consideration in many aspects, the drop irrigation amount 300-350m3/667m2 could as the reference standard of this locality jujube orchard intercropping.


The present study was carried out within the Quito canton, with the objective of evaluating the quality and knowing which activities within the check list have the highest incidence for the sanitary and hygienic quality of the milk. It took three altitudinal floors and two sizes of the UPA, having as best results for sanitary quality all the producers that are in the lowest altitudinal floor that goes from 150 to 1800 meters above sea level and the large producers of the altitudinal floor greater than 3000 meters above sea level. In the hygienic quality the best results were the large producers of milk at a height between 1800 to 3000 masl and all the producers who are at a height of less than 1800 masl. All the aforementioned treatments complied with current INEN 9 regulations for raw milk. The results of the most influential activities in hygienic quality were: Some type of additional treatment is done to improve water quality, wash your hands during milking after each contamination, Disinfect the teats with a specific product for this (PRESELLADO), Instantaneously after the milking, the milk is cooled to 4 ° in less than 2 hours and in the sanitary quality there was only one highly significant activity which was: It has a milking order according to the CMT. In the collection centers, the results showed that only 35.71 percent of hygienic quality comply with the regulations, concluding that there is bad management in the cold since the quality of the farms does not exceed the averages shown by the collection centers.


.................................................................................................. (iv) Table of contents...................................................................................... .... (v) CHAPTER ONE 1.0 Introduction.......................................................................................1 1.1 Background of the study......................................................................1 1.2 Statement of the Problem................................................................... ....5 1.3 Objective of the Study...........................................................................6 1.4 Importance of the Study........................................................................ 6 CHAPTER TWO 2.0 Literature Review..............................................................................8 2.


Unemployment is analyzed from a philosophical approach, as a never questioned side of the categorical imperative of working in western societies. Problems towards the end of work arisen by the postindustrial era are tackled in this part. Subsequently, documentary research is carried out to detect the presence of hate speeches, more or less subtle, about unemployed. Lastly, we deal with the problem about how to analyze, from pragmatics theory, the normative dimension of hate speech about unemployed.


This article explores Web 2.0 in interactive learning environments. Specifically, the article examines Web 2.0 as an interactive learning platform that holds potential, but is also limited by learning styles and cultural value preferences. The article explores the issue of control from both teacher and learner perspectives, and in particular the cultural challenges that impact learner control. From the control perspective, the issue of access to Web 2.0 technologies from both cost affordability and government censorship is also addressed. Finally, the article concludes with implications and recommendations for Web 2.0 learning environments.


An independent review of a 150-bed nursing home run by Takare found there were too few qualified staff to provide quality care in its first months.


6-Phosphogluconate dehydrogenase from human erythrocytes has been purified 5000-fold from haemolysates with an overall yield of 6%.

Bulk fractionations followed by gradient elutions were carried out on DEAE-Sephadex and CM-Sephadex, and gel-filtration on Sephadex G-200. Ammonium sulphate fractionations were used after the CM-Sephadex and Sephadex G-200 steps.

The final preparation had a specific activity of 10 units/mg, and was homogeneous on ultracentrifugation. Although other proteins were absent, electrophoresis indicated the presence of isoenzymes. The pruification procedure was completed in 3 weeks, and gave 50 mg enzyme from 35 l blood. The procedure allows the concurrent isolation of glucose-6-phosphate dehydrogenase.

The dependence of the enzyme activity on ionic stregth, pH and NADPH was investigated. Under cellular conditions the total potential activity is the same for the two hexosemonophosphate dehydrogenases. The flow through the pathway would be controlled by the level of NADPH.


Relay installed on the mobile device together with the identification numbers of all mobile communication terminals subordinate to itself, by notifying an own identification number to a mobile communication network, and performs a batch update of the location registration area information of these mobile communication terminals. The relay apparatus receives the call request to the batch aggregation the call request to a plurality of subordinate mobile communication terminal, by reconfiguring the received batch call request, transmits the call request to the mobile communication terminals subordinate to itself, respectively.