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Tuesday, April 29, 2008
Pierre Hermé in Singapore
Anyway, my point is, Singaporeans are a well-traveled bunch and coming from a food-loving culture, they eat where they go at the best places they can find. As a result, mention any internationally renowned chef to any globe trotting Singaporean and chances are he/she has not only heard of the chef but has also eaten at the famed establishment. It is therefore no surprise that each year at the World Gourmet Summit held in town the list of guest chef looks like the who's who of the culinary world. I missed the one last year because I was back in the States helping my parents move, i.e. tossing out high school report cards, college notebooks and even my wedding dress from their basement.
This year, I made sure I was in town during the WGS and I am so glad I did, because Pierre Hermé, the man who single handedly changed the way desserts are made and presented was one of the guest chefs.
I have long been a fan of Mr. PH ever since my Tokyo days and have visited his store in Paris as well. He may not be my all-time favorite pastry chef ever (that honor goes to Mr. Hidemi Sugino), but his innovative flavor combinations never cease to amaze and inspire me. Naturally, when my friend called to tell me that he's going to be serving his signature desserts at Mezza9 I wanted to make a reservation right away. I also wanted to attend his master class, however I was not as decisive in that front. So in the time it took me to come to the conclusion that yes, I really do want to watch him from the back of an auditorium that seats 200, all the tickets were sold out. At least we booked our seats at the Mezza9 early enough.
After more than a month the day finally came. The six of us agreed (or rather, the wives decided on behalf of the husbands) to order a light dinner so we could try all seven desserts on the menu. In true Singapore "kiasu" style we pre-ordered our desserts before our meals, just in case any particular item runs out. While we were deciding what main dishes to order, Mr. Pierre Hermé stepped out into the dining room and all of a sudden I could feel my heart palpitating. He came over to our table and I asked Jason to take a photo for me with the master himself, then another one with all three ladies at the table. Normally I am not the type to swoon over a movie or rock star but I found myself gushing in the presence of Mr. PH. So it was in the presence of an iconic chef that I finally got a little taste of what screaming fans must feel when they're faced with their idol.
At the waiter's urge we ordered some side dishes to go with the main, but the main dish portions turned out to be very generous. I had almost half a duck on my plate and in order to conserve precious stomach space I had to give most of it to Jason. When finally the dishes were cleared away we ordered a bottle of dessert wine and waited for the arrival of Mr. PH's masterpieces.
Now, in the order of flavors going from lightest to heaviest, they are:
Dessert Ispahan – rose flavored macaron filled with rose petal cream with raspberries and lychees, served with sorbet ispahan: lychee, rose petal aromas and raspberry sorbet.
I have had both the ispahan (macaron) and the sorbet (in the form of and ice cream bar, named Miss Gla-gla), which are both excellent on their own. But I have to say that having them side by side like this, when you chase the ispahan macaron with a light, refreshing bite of the sorbet, you'll understand why this is his best known dessert.
Emotion Satine – compote of passion fruit, seasoned orange segments, cream cheese cream, topped with shortbread cubes soaked in flavored syrup.
I have also had this while in Tokyo, when the range was first introduced. I've always liked the tartness of passion fruit, especially when it's paired with something sweet and creamy. One of my favorite elements of this dessert is the shortbread on top. People are weary because they look like brown sugar cubes but of course when you pop one into your mouth you'll immediately realize your mistake.
Revelation – puff pastry with tomato, mascarpone cream, olive oil, pieces of black olives, tomato and strawberry compote.
There is a split of opinion on this dessert, with only two guys in our group liking it. Usually I am the first to order something weird like this because I am always for trying new flavors, but even for me this is a little strange. Don't get me wrong, I have nothing against tomatoes in desserts, it is a fruit after all. In fact, one of my favorite tarts was a cherry tomato tart from a bakery in Tokyo. However, the revelation lacks the magic element that pulls all the components together, so the tomato tasted like salad and the olives seemed really out of place.
Tarte Mogador – shortcrust pastry filled with milk chocolate and passion fruit ganache, with a piece of flourless chocolate cake inside, topped with roasted pineapple
Here is another one I did not like. For one, the short crust pastry shell was really hard and very difficult to cut, and then there's the problem of the pineapple. Maybe the Hyatt couldn't get a good batch, but it was kind of tasteless. Then there's the cacao nibs. I confess I've never been a fan of cacao nibs, and especially not in ganache. I am all for contrast of textures, but biting into cacao nibs in an otherwise silky and smooth ganache is like finding coffee grinds in a nice cup of latte. It's just not my thing. Sorry, Mr. Hermé!
The next dessert has no name but only a description: variation of chestnut, passion fruit and matcha green tea.
The bottom half of the martini glass was filled with a silky custard so rich and creamy and full of egg flavors I couldn't stop eating. Then there was a layer of sweet chestnut cream and a layer of matcha mouse. Passion fruit pulp was drizzled on top to give this sweet and rich dessert some zing. The scoop of ice cream lent a nice contrast in temperature and it was all rounded off nicely with a paper-thin tuille. This is more like the Pierre Hermé I know.
Crème brulee with foie gras, cranberries and pear compote
Ladies and gentlemen, this is by no means your regular crème brulee! Although I eat foie gras at every chance I get, I've never had it in a dessert and to be perfectly honest, I had my doubts: will it be too rich, will it be too weird? All my doubts were dispelled the moment I took a tentative little bite. Oh how do I describe it? You know when you eat foie gras, you like the intense rich flavor but the burst of oil in your mouth is not really pleasant? Well, somehow Mr. Hermé managed to solve that problem. You taste the intense fragrance of the foie gras without the greasiness because, me thinks, it is first neutralized by the custard cream and further played down by the refreshing combination of cranberry/pear compote and fresh pear chunks. In the words of Randy Jackson, (watch American Idol much?) "Yo, listen dude, this is molten HOT!"
And last but not the least, an assortment of macarons:
The vanilla was too sweet for my taste and the chocolate had the same problem with the tarte: cacao nibs in ganache. I didn't try the passion fruit milk chocolate ganache macaron but I really enjoyed the rose flavored ispahan, again. My favorite, however, was the white truffle. I know it sounds so cliché, but I really did enjoy it the most. I know it's hard to make a good truffle dessert because I've had some pretty bad truffle ice creams before. Nevertheless, when it's done right, it is the most incredible experience of flavor and aroma, which PH managed to do in perfection. The fragrance of the truffle is neither too pungent nor too subtle and the flavor is neither too intrusive nor too delicate. And with that perfect macaron we finished off our wonderful dessert course.
I was feeling content and happy about the whole experience, until the next day, when I found out that there was actually another different dessert menu just next door in the Martini bar. Had I known that I would've convinced my dinner companions to skip dinner altogether and order that entire menu too! Oh well, there is always Paris and Tokyo. Until then, Mr. Hermé.
10 comments:
- Mad Baker said...
Lynn, your photos do his desserts so much more justice than the ones I took! We didn't fancy the Tarte Mogador either; the crust was hard and I thought the pineapples tasted burnt. After reading your post, I realise that it must have been the cocoa nibs!
I enjoyed your blog. Did it take you long to get your desserts? I mean all of the dessert items for the most prt ares so complicated and meticulous. Do you know if a place like that would have all the pieces to say the creme brule on the side so they just assemble them?
- Mandy said...
that's a great review, Lynn!I will be just as excited if I met Mr PH in person!
- Grace said...
foi gras creme brulee sounds really gross, yet your description made it sound really appealing!
- baobei said...
And I didnt go!!
I had the Emotion Satine before, and of course Isaphan..
Would have been interesting to try the rest!!
And of course the Martini bar ones!!!
There's always room for PH desserts
- Lynn said...
Karen, did you post any of your photos? I wanted to see what you had at the martini bar!
carochan, I think most were pre-made and they just add the garnish, etc before bringing it out.
mandy, thank you! He was not very talkative though, or maybe it was because I did all the talking =oP
grace, haha, trust me, it was really good!
baobei, yeah, I wish I tried them all =o(
- Mad Baker said...
Lynn, we only had the "dessert carrément chocolat" from the martini bar menu.
Bottom left of collage: http://www.flickr.com/photos/madbaker/2422846621/
The waiter was kind enough to serve it to us in the main restaurant. I really wanted to have the tarte vanilla and emotion céleste too, but we were already too full!
- Cheryl said...
Wow, thanks for sharing. I'm usually the skeptical sort, but this post has inspired me to try something new.
Love your photos and your blog btw! :)
Was aware of the Gourmet summit for some years but somehow didn't realise that PH made a presence last year (probably as I was away for a while). Anyway just came back from his Rue Bonaparte's in Paris and you'll know Singapore's macarons are just not anywhere near the real thing. Counting down to the day I can taste that rose macaron and Ispahan again.
- Karla - Pitchers said...
Looks tasty! I'm going to try that one at home.


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Monday evening David and I (Christopher) packed up our bags and headed to Brevard, North Carolina where we would set up camp and get a good night's rest in preparation for today's big first stage of the 2010 Pisgah Mountain Bike Stage Race. We rented a van for the drive since we have a tendency to overpack (why not bring 2 spare bikes, and extra wheels, spare tires, and…well, you get the point):
This morning came early as we were up with the sunrise in order to make up breakfast and drive to the start of the stage (although the temp would warm up nicely, it was chilly early in the morning).
This was the only stage we will have to drive to and thank goodness! The drive was rough! There was over 6 miles of gravel road that apparently doesn't see too much care and our rental van was barely up to the challenge (it sounded like someone threw a handful of quarters into a clothes dryer).
None the worse for wear, we arrived at the start with plenty of time to sign in and get warmed up. The finish line was at the beautiful Blue Moon on Pinnacle Peak, which had a spectacular view:
Another cool feature of the race was that we all had to sign in before the stage (like they do in the Tour de France). Here I am signing in, getting as close to Jeremiah Bishop as I would all day!
Here we are, ready to go, in our Performance team kits, next to our GT Sensor 9rs:
Stage 1 was touted as the easiest of the 5 stages. We started by all rolling out for a neutral (not racing) 7 mile ride to the start line (mostly downhill). Then as a surprise we faced a Le Mans start (which is where you have to run and pick up your bike, always an amusing sight at a bike race) before facing "Dupont Forest's rockiest terrain". The stage consisted of a 12 mile climb (with brief glorious downhill sections) to take us back up to the finish line. The highlight of the day was David flying headfirst into a deep stream crossing–he took the race promoter's word seriously when he said that everything on the stage was rideable! Someone was actually on the scene taking a video, so we will post it as soon as we find out who it was filming. The battle was hard fought but in the end, we weren't last!
Waiting for us at the finish line was a field full of happy participants and very nice lunches (Jeremiah Bishop won the stage, of course, in a close fought battle–or so we're told!)
As we sat and ate we pondered what tomorrow would bring. Today was an hour and a half of very difficult trail. Tomorrow will bring more than three times that. Should be fun!
Final stats for the day: 12.16 miles and 2,540 feet of vertical gain:

subset: commoncrawl


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We might, but some people just don't buy it. No wonder sales are down.
Is there a hard line between rock and soul, or are there some tunes that bridge the gap? Instead of trying to pick and chose, saying, "I am morally obligated to 'you' (soul), but not to 'it' (rock), wouldn't it be easier just to be morally resposible toward all? On second thought, there's heavy metal and rap. We certainly can't be morally responsible toward heavy metal and rap. It's like, if I argued with Sam, saying that we Do have a moral obligation toward rocks, I'd go on to postulate that we do not have a moral obligation to radioactive rocks.
In other words, now I'm thinking that if something harms us, we cease to have a moral obligation towards it. So, in music, we need some kind of instrument, like a Geiger counter, that can measure what is music and what isn't - what entertains and enlivens us, and what harms us - you know, damages the cochlea or currupts the youth. However, then we'd need a music police to drive around to the different clubs to take readings and shut down offenders. I can see the morning headlines now: PLYWOOD FACTORY SHUT DOWN BY MISTAKE - Music Police mistake factory for nightclub - take reading on log peeler. Jail filled with angry plywood workers who threaten to sue city.
Some dualists imagine this is possible. I scoff at their fantasies. There has been no demonstration that they can be considered separate entities. You have to revert to the primordial Ylem of popular music, the Blues. But quick as a wink, you will find yourself listening to Ragtime, and shortly thereafter, to Schubert. Or possibly Bach. Or Yoruba folk songs.
The only escape from this infinite regress is Tuvan Throat Singing. These are truly gravelly vocals. Which does bring us back to rocks.
Talk about yer duality.
Some dualists imagine this is possible. I scoff at their fantasies. There has been no demonstration that they can be considered separate entities. You have to revert to the primordial Ylem of popular music, the Blues. But quick as a wink, you will find yourself listening to Ragtime, and shortly thereafter, to Schubert. Or possibly Bach. Or Yoruba folk songs.
The only escape from this infinite regress is Tuvan Throat Singing. These are truly gravelly vocals. Which does bring us back to rocks.
Without, to my knowledge, ever having heard Tuvan Throat Singing, the mention of it conjured an image of a Neanderthal clan sitting around the fire on the evening the first song was born. Off in the gloaming, some wolves howled, first on one hillside, then an answer from another. One caveman howled in response, for fun, and the wolves answered. Then the whole clan joined the sport, and they noticed some harmony, that it was fun, and they kept it up for a full 20 minutes. The next night, baby Yorga went missing, and singing was banned henceforth, not to resurface for another twenty-three thousand years.
When I was a child, I was told not to whistle in the bathroom. I think my mother had seen a horror movie in her youth, in which this activity was unwise.
I once wrote a WWII screenplay. In one scene I have over 300 German bombers passing over the White Cliffs of Dover on a bright moonlit night. Picture it. They are passing through a formation of small white clouds. Though maintaining radio silence, the pilots are all in a good mood. They wave to each other, and point down to the cliffs, and to a signal light flashing offshore from a U-boat.
Then, in the distance, they see the approaching Spitfires and Hurricanes, and searchlights begin piercing the sky. On the manuscript, I scribble in instructions for Wagner's 'Ride of the Valkyries' to begin. Imagine my embarrasment when I was told that this music had already been used for the flight of American Hueys in Coppola's 'Apocalypse Now'. Imagine how my embarrasment turned to humiliation when I remembered that I had seen 'Apocalypse Now' years before.
That screenplaly still lies in a drawer, waiting for new inspiration for the score. Schubert or Bach won't do. How does Tuvan Thoat Singing go? Anything Germanic about it?
Not a bit Germanic. The most amazing thing about it is that they sing two notes at the same time. Kind of like some birds can. So it's more avian than German. Might work for those planes, or you could just use bird songs. I'd suggest House Wren and Yellow Warbler. Or maybe The Beatles' Flying. They used to play in Germany.
Not a bit Germanic. The most amazing thing about it is that they sing two notes at the same time. Kind of like some birds can. So it's more avian than German. Might work for those planes, or you could just use bird songs. I'd suggest House Wren and Yellow Warbler. Or maybe The Beatles' Flying. They used to play in Germany.
Listen, I'll bet Lawrence Welk had some gigs in Germany, and did a few numbers with lederhosen and yodeling. That's not enough. And House Wrens and Yellow Warblers won't do. You're not even trying.! Try to get the picture: Now, the bomber escort, the Messerschmitts, tilt in unison, drop away from the bombers, then come up under the Spitfires and Hurricanes which, in response, fan out and veer up toward the bombers.
Swallows, maybe, but remember it's 2 A.M. Something nocturnal, ominous, fateful, - you see why I'm stuck? It's Wagner. Anything on the Dobro?
Peacocks! Lots of peacocks! Ever hear them scream? Aaaaaahhhhhhhhhhhhhhhkkkk…...!
[quote author="g.wood"]Peacocks! Lots of peacocks! Ever hear them scream? Aaaaaahhhhhhhhhhhhhhhkkkk…...!
Odd that you should mention peacocks. My neighbor has them. Even though there's a third of a mile of impenetrable woods between us . . .
And, true, nightfall means nothing to them. I suppose he's got one of those halogen streetlights to discourage people from creeping into his yard at night with a blunderbuss.
What is he, a Nazi or something? Well, there you go, live recording. Layer it all up with lots of crazy pan and reverb, those Messerschmidts will scare the bejeezus out of 'em, much better than Herr Wagner.
What is he, a Nazi or something? Well, there you go, live recording. Layer it all up with lots of crazy pan and reverb, those Messerschmitts will scare the bejeezus out of 'em, much better than Herr Wagner.
The Unknown WWII
Yesterday the flying ants emerged for their annual nuptial celebration, and at twilight I was watching the bats swooping over the trees picking them off. That's when it came to me - Strausse's Die Fledermaus! And, get this, I'll interject the bats' sonar into the music, made audible to the human ear. See what I mean? Hitler and Strausse were both from Austria, Britain was using radar for the first time, and bats use sonar to navigate in the dark! Perfect.
Further, your idea for crazy pan and reverb shook me out of my stodgy plot and dialogue - stuff we've seen and heard a hundred times. So, the Messerschmitts get low on fuel, and have to head home, leaving the bombers to fend for themselves as they continue on to their target - Clydebank Shipyards near Glasgow. So, now we have a waltz from Die Fledermaus as the Spitfires and Hurricanes bank gracefully, picking off their lumbering prey - instead of machine guns we hear the bats' sonar as they close in for the kill. A bomber bursts into flames and the crew bails out, drifting peacefully downthrough the small white clouds over the Scotish countryside. This is where the plot becomes totally unpredictable. One of the chutists lands accidentally on a barrage balloon, and we have cameras in a helicopter filming him tramping spongily around on the balloon, unhooking his collapsed chute, hanging onto cords and peering down over the edge - trapped 500 feet above the ground!
Now we cut to the blitz itself. Not only are the shipyards destroyed, but a whiskey distillery has been hit. The Germans look down in astonishment to see a blazing river of whiskey winding its way toward the Clyde River. This is a side of World War II that no one has seen before, but it happened.
Now the bombers, what's left of them, are going home. One of them finds that he's still got a bomb left over and he drops it on Glasgow where it hits the Glasgow Menagerie. An elephant is running down the street headed for Kelvin Grove, and, (here we use the peacocks in the soundtrack); a pack of monkeys rushes into an air raid shelter where the children, who have been thoroughly propagandized, think that they are Nazis. I won't give away any more, but anyway, it's all coming together very nicely, and I may have it ready in time to compete with PBS's Ken Burns WWII special. If Fox buys it I'll send you 10% of the royalties for the peacock input.
Well, I'm flabbergasted. That was much more engaging than lumbering through the minutia of Why Religion Is Crazy and if we give a good yeehaw about rocks.
It has happened before, but there is nothing to compare it to now.
I actually got farther with it than just that sentence.
And those weren't Messerschmitts, but only a bunch of Fokkers.
The Messerschmitts were all shot down because they had no "D".
I went back and fixed Willy's name wherever I could. I wouldn't like it if someone called me 'unsmoket'.
You make a good point about taking into account the value of certain "rocks" when determining whether and what ethical obligations we have in various situations.
I don't read Sam Harris's "rock" point to conflict with yours. His basic point (oversimplified) is that generally we owe ethical obligations to biological beings (some would say just to humans, others to some or all animals and plants) and not to inanimate objects. He chose a "rock" to illustrate his point. I presume he had in mind any of the countless garden-variety rocks one commonly sees. True, one could suppose that a reference to a "rock" would encompass even a special rock, like the Buddhist statue, or a massive collection of rocks, like a mountain or the entire planet, but that would, I think, stretch Harris's simple reference far beyond anything he meant and far beyond anything he needed to mean to make his point.
AmericanHumanist, I think, sought to make much the same point that ethical obligations are between biological beings, and rocks are implicated only to the extent that they play a role in the ethical obligations we owe other biological beings, whether human or otherwise. The end result may be much as you advocate, i.e., we should refrain from blowing up the statue or house or planet because to do so would violate our ethical obligations to each other and to the other beings inhabiting the world.


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This is an archived article that was published on sltrib.com in 2012, and information in the article may be outdated. It is provided only for personal research purposes and may not be reprinted.
Orem • Gov. Gary Herbert says the swift, efficient rebuild of Interstate 15 in Utah County vindicates controversial state decisions about awarding the $1.1 billion contract even if bid scores were tweaked, giving it to some of his big political donors.
"As we look at it today in hindsight, we see UDOT [the Utah Department of Transportation] made the right decision in awarding the contract to the right people," he said during a tour Wednesday of the project, where he was told it is $230 million under budget and two years ahead of original schedule.
"You can look at SR-92 and see the contrast" between work done by winners and losers of the I-15 bid, Herbert said.
The smaller $170 million rebuild of State Road 92 from Lehi to Alpine was just finished 10 months behind schedule amid quality complaints, and after $4.5 million in late fees charged to the contractor, Flatiron/Harper Joint Venture. Flatiron was part of a consortium that lost the bid for the I-15 work.
That consortium was quietly paid $13 million by UDOT in 2010, when it contended it was cheated out of the $1.1 billion contract. After bid scores were tweaked, Provo River Constructors won that contract by one point. Company officials had contributed $82,500 to Herbert's campaign in months before the contract was awarded.
Audits later found no wrongdoing or political pressure by UDOT and Herbert over the bid, but a state auditor's report said auditors couldn't determine whether the bid process and settlement payment were fair because of a lack of documentation. That review also criticized UDOT for not concealing identities of the bidders, providing misleading information to one bidder about how proposals would be evaluated and for including on the UDOT evaluation team a person married to an employee of one of the bidding contractors.
The governor said the proof is in the product.
"You can see the difference between a $1 billion project here, and a significantly smaller project that is just now getting completed and is way overdue," Herbert said. "So you can do the math. And the quality of SR-92 they've had to make them go back and fix" several problems.
Meanwhile, the governor noted that the rebuild of I-15 "is going to come in under budget, with $230 million in savings that will go to other projects."
"It is the fastest billion-dollar job ever done in this country," Carlos Braceras, UDOT deputy director, said on the tour. "Even more amazing is that was done while almost all of the lanes were open almost all of the time."
UDOT Director John Njord said the work was managed "even though everyone was ready for 'carmageddon' when we started this project."
Herbert said the controversial $13 million payment to losers of the I-15 bid had some unseen benefits, because it gave UDOT rights to the losers' designs and ideas.
As he toured construction at the Provo Center Street interchange, Provo Mayor John Curtis told him it had been completely redesigned more to the preferences of the city using drawings of losing bidders. "People don't realize that benefit," Herbert said.
Meanwhile, Herbert's Democratic opponent this year, Peter Cooke, said the governor "is a little confused that the ends justifies the means." He criticized Herbert for accepting donations from people bidding on major projects and says he would not do that.
Cooke also assailed the payment of $13 million to losing bidders.
"You only do that when the process is very flawed, and now he's trying to justify that," Cooke said. "It's nice the project is $230 million under budget, but that should have been $243 million."
Herbert decided to leave his mark, literally, on the project Wednesday. As if it is were Grauman's Chinese Theatre in Hollywood, he and Lt. Gov. Greg Bell put their handprints and signatures in wet cement at the Orem Center Street interchange.
Herbert challenged crews to finish the project even faster, by Thanksgiving along main I-15 lanes to help ease holiday traffic. Tim Odell, deputy director for construction for Provo River Constructors, said that would be "very likely."
Herbert interrupted him and said, "It's highly probable." So Odell said, "Highly probable."
The governor added that fast growth in the state creates continuing need for more highways and mass transit projects. "It will be a challenge to keep ahead of the growth."
In discussions on the tour, Herbert said the state may need to look at raising the gasoline tax which has not been increased since 1997 to handle future envisioned projects. A recent transportation plan for the future by UDOT, the Utah Transit Authority and regional planning agencies projects a $27 billion shortfall for needed transportation projects during the next 30 years.
I-15 Utah County rebuild
• Construction cost is $1.1 billion, and total cost (including land) is $1.73 billion.
• It is projected to come $230 million under budget.
• Length is 26 miles from Lehi to Spanish Fork.
• Expected completion in December is two years ahead of original schedule.
• Fun fact: It used enough concrete to build a 5-foot wide sidewalk from coast to coast.


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Twittering By Dictaphone
Harvey Pekar is Twittering via surrogate, an advice columnist is complimenting herself via email archive and a radio producer is turning a movie theater into her own personal catwalk. The Twitterati are doing a little role playing.
Comic-book writer Harvey Pekar is now Twittering, in the most Pekaresque way possible.
Advice columnist Penelope Trunk is an email-address autocomplete disaster waiting to happen.
Science writer Clive Thompson's reaction to a sophisticated robot hand was definitely not a childlike sense of wonder.
Patty Rodriguez, writer for Ryan Seacrest, isn't going to just any old movie, and she's not dressing that way either.
The Chicago Tribune's Rex Huppke became a cautionary tale on when a kid should not be a kid.
Did you witness the media elite tweet something indiscreet? Please email us your favorite tweets - or send us more Twitter usernames.


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Ribonuclease H (RNase H) is an endoribonuclease which specifically degrades the RNA strand of an RNA-DNA hybrid to produce 5' phosphateterminated oligoribonucleotides and single-stranded DNA. It is suitable for removing mRNA during second strand cDNA synthesis, removing the poly(A) sequences from mRNA in the presence of oligo(dT), and for oligodeoxyribonucleotide-directed cleavage of RNA. RNase H is purified from E. coli expressing the E. coli RNase H gene on a plasmid.
Unit Definition
One unit is defined as the amount of RNase H that solubilizes 1 nmol poly(A) in 20 minutes at +37°C
Storage Buffer
20 mM Tris-HCl (pH 7.5)
100 mM KCl
10 mM MgCl2
0.1 mM EDTA
0.1 mM DTT
50 μg/ml BSA
50% (v/v) glycerol
Quality Control
Product qualification is described in the Certificate of Analysis (CofA), available on our website by product lot number at www.lifetechnologies.com/cofa.


text:
Join our live RV chat - click HERE
If you do a search you will find several prior threads on this subject.
Are you trying to find out if a Class B would be more acceptable for this type of street/parking lot camping than a Class A?
My gut feeling is anyone who spends the night in any type of vehicle is the issue; not what type of vehicle. And I bet there are exceptions occasionally, like the Rose Parade this morning. I'm sure tons of people spent the night in their cars waiting to go see the Rose Parade and they didn't get hassled
What jurisdiction/state is it that is making an enforcement push?
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text: Job Discussion Forums :: View topic - Is there such thing as Border Run in Ukraine? Get TEFL Certified & Start Your Adventure Today! Job Discussion Forums"The Internet's Meeting Place for ESL/EFL Students and Teachers from Around the World!" FAQ Search Memberlist Usergroups Register Profile Log in to check your private messages Log in Is there such thing as Border Run in Ukraine? Job Discussion Forums Forum Index -> Ukraine View previous topic :: View next topic Author Message Start123Joined: 03 Dec 2010Posts: 9 Posted: Mon Dec 13, 2010 6:59 pm Post subject: Is there such thing as Border Run in Ukraine? I'd like to consider Kiev as a place to work, however I'd like not to work for anyone but myself. After 90 days...can you do a border run to Germany for example and come back for another 90 days? Back to top 1Sapphire1Joined: 17 Aug 2009Posts: 41Location: Saudi Arabia Posted: Mon Dec 13, 2010 9:51 pm Post subject: A visa is required to come to Ukraine unless you are from a country with visa-free privileges such as the USA. In this case you do not need a visa for a stay of up to 90 days if the purpose of your visit is visiting friends or family, travel, personal business. (You do need a visa for: employment, university studies, diplomatic service, church mission, permanent residency, immigration.) A visa is also required for stays of more than 90 days in a row or for more than 90 days total out of any 180 consecutive days. Once in Ukraine, some categories of foreigners who have visas may need to register with the city OVIR (Office of Visas and Registrations) For example: for a private, business, or tourism visa, registration is required only for stays of more than 90 days continuously in Ukraine; registration avoidable through "border runs"; registration process must be begun near end of 90 day period from most recent border crossing. By having a visa you may not have to leave the country every 90 days but you would have to register with the OVIR and may have to pay them a fee. By doing a border run every 90 days you avoid registering with the government and will not have to pay a fee. It is generally recognized among expats that making periodic trips to one of Ukraine's international border crossings is actually easier than going through the registration process. However, some categories of foreigners cannot avoid registration: those with student visas or work visas those applying for permanent residency those with business, private, service, and some other types of visas who fail to make regular border crossings, either through international travel or "border runs" Furthermore, border runs may become impossible some time in the future and are actually not completely legal at the moment, since holders of business and private visas are technically not allowed to spend more than 90 out of any 180 consecutive days in Ukraine. However, this point of regulations is not being widely enforced. Brace yourself... Visits to the OVIR are often frustrating because of OVIR workers' unwillingness to answer questions and offer information. You may end up wasting time standing in line, visiting the OVIR just to find out the office hours, and having to return because the officer will not talk to you unless you show them document X. Bring all possibly relevant documents (esp. Back to top Start123Joined: 03 Dec 2010Posts: 9 Posted: Tue Dec 14, 2010 5:29 pm Post subject: I noticed that about Russians( or Ukranians), you ask them a simple YES or NO question and they start telling you the story about the moon and the Sun and maybe rain,or maybe stars...wtf? Is it ok to re-enter Ukraine to reset your supposedly tourist visit for another 90 days?...USA passport if it matters. Back to top 1Sapphire1Joined: 17 Aug 2009Posts: 41Location: Saudi Arabia Posted: Tue Dec 14, 2010 9:16 pm Post subject: Sorry it was so long. I just copied and pasted from something that I already had on Word. Yes you can leave the country every 90 days with or without a visa. I have a friend that doesn't have a visa who does this. (I do it also but I have a visa. We both have US passports. The cheapest option is just to go to Moldova) However while it can be done it is against the rules so if they do stricter enforcement you may have a problem. Back to top Start123Joined: 03 Dec 2010Posts: 9 Posted: Sun Dec 19, 2010 8:08 pm Post subject: 1Sapphire1 wrote: Sorry it was so long. I just copied and pasted from something that I already had on Word. Yes you can leave the country every 90 days with or without a visa. I have a friend that doesn't have a visa who does this. (I do it also but I have a visa. We both have US passports. The cheapest option is just to go to Moldova) However while it can be done it is against the rules so if they do stricter enforcement you may have a problem. Thanks man! I've heard similar reports that you can do it. I used to fly to Germany from Borispol on Wizzair really cheap! Around 50USD return...i recall. Now it looks around 200 USD. Must be the season! How do go to Moldova? By bus or train? What's the cost? Thanks again! Back to top Display posts from previous: All Posts1 Day7 Days2 Weeks1 Month3 Months6 Months1 Year Oldest FirstNewest First Job Discussion Forums Forum Index -> Ukraine All times are GMT Page 1 of 1 Jump to: Select a forum Where to Begin----------------General DiscussionNewbie ForumCurrent Events ForumTechnology ForumOnline Teaching Forum Africa Forums----------------General Africa Forum Asia Forums----------------CambodiaChina (Job-related Posts Only)China (Off-Topic)Hong KongIndiaIndonesiaJapanMalaysiaPhilippinesSingaporeTaiwanThailandGeneral Asia ForumVietnam Caribbean Forums----------------General Caribbean Forum Europe Forums----------------Czech RepublicFranceGermanyGreeceItalyMacedonia and the BalkansPolandRomaniaRussia & C.I.S.SpainTurkeyUkraineUnited KingdomGeneral Europe Forum Latin America Forums----------------ArgentinaBrazilChileColombiaCosta RicaMexicoMexico (off-topic)PeruGeneral Latin America Forum The Middle East Forums----------------BahrainEgyptIsraelKuwaitOmanQatarSaudi ArabiaUnited Arab EmiratesGeneral Middle East Forum North America Forums----------------General North America Forum Oceania----------------Australia/New Zealand You cannot post new topics in this forumYou cannot reply to topics in this forumYou cannot edit your posts in this forumYou cannot delete your posts in this forumYou cannot vote in polls in this forum This page is maintained by the one and only Dave Sperling. 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Development of Local Composting Programs
The landscape management practices of residents will have to be changed as yard waste management practices are incorporated within the overall solid waste management system of a community. However, with careful planning and an aggressive public education program, a successful yard waste management strategy can be designed and implemented which will allow homeowners to participate through a program that suits their lifestyle.
As Indiana communities plan for the future, yard waste management programs are recommended as a way to achieve solid waste diversion goals and comply with Indiana's Yard Waste Disposal Ban which has been in effect since September 30,1994.
- How to register a Yard Waste Facility [PDF]
- Indiana's Registered Composting Facilities [PDF]
- Regulations for a Compost Facility
- State Open Burning Regulations
- Local Open Burning Bans


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He perceived that the Liberal ministry had offended certain influential sections by appearing too demiss or too unenterprising in foreign affairs.Bryce.
A coiner or a smuggler shall get off tolerably well.Lamb. The same circumstance may make one person laugh, which shall render another very serious.Lamb. You shall hear the same persons say that George Barnwell is very natural, and Othello is very natural.Lamb. Don Quixote shall last you a month for breakfast reading.Spectator. Take them as they come, you shall find in the common people a surly indifference.Emerson.
Some of us, like Mr. Andrew Lang for instance, cannot away with a person who does not care for Scott or Dickens.Spectator. One needs not praise their courage.Emerson. What turn things are likely to take if this version be persisted in is a matter for speculation.Times. If Mr. Hobhouse's analysis of the vices of popular government be correct, much more would seem to be needed.Times. Mr. Bowen has been, not recalled, but ordered to Washington, and will be expected to produce proof, if any he have, of his charges against Mr. Loomis.Times. It were futile to attempt to deprive it of its real meaning.Times. It were idle to deny that the revolutionary movement in Russia is nowhere followed with keener interest than in this country.Times. It were idle to deny that coming immediately after the Tangier demonstration it assumes special and unmistakable significance.Times. He is putting poetic 'frills', if the phrase be not too mean, on what is better stated in the prose summary of the argument.Times.
Under them the land is being rapidly frivolled away, and, unless immediate action be taken, the country will be so tied that...Times. That will depend a good deal on whether he be shocked by the cynicism of the most veracious of all possible representations...H. James. We may not quote the lengthy passage here: it is probably familiar to many readers.Times.
'I have no particular business at L.,' said he; 'I was merely going thither to pass a day or two.'Borrow. I am afraid you will hardly be able to ride your horse thither in time to dispose of him.Borrow. It will necessitate my recurring thereto in the House of Commons.Spectator. The Scottish Free Church had theretofore prided itself upon the rigidity of its orthodoxy.Bryce. The special interests of France in Morocco, whereof the recognition by Great Britain and Spain forms the basis of the international agreements concluded last year by the French Government.Times. To what extent has any philosophy or any revelation assured us hereof till now?F. W. H. Myers. On the concert I need not dwell; the reader would not care to have my impressions thereanent.C. Brontë.
Nobody save an individual in no condition to distinguish a hawk from a handsaw...Times. My ignorance as to 'figure of merit' is of no moment save to myself.Times. This we obtain by allowing imports to go untaxed save only for revenue purposes.Spectator. Who now reads Barry Cornwall or Talfourd save only in connexion with their memorials of the rusty little man in black?Times. In my opinion the movements may be attributed to unconscious cerebration, save in those cases in which it is provoked wilfully.Times. When Mr. Roosevelt was but barely elected Governor of New York, when Mr. Bryan was once and again by mounting majorities excused from service at the White House, perchance neither correctly forecasted the actual result.Times. Dr. Bretton was a cicerone after my own heart; he would take me betimes ere the galleries were filled.C. Brontë. He is certainly not cruising on a trade route, or his presence would long ere this have been reported.Times. Mr. Shaynor unlocked a drawer, and ere he began to write, took out a meagre bundle of letters.Kipling. Fortifications are fixed, immobile defences, and, in time of war, must await the coming of an enemy ere they can exercise their powers of offence.Times. 'It is something in this fashion', she cried out ere long; 'the man is too romantic and devoted.'C. Brontë. Ere departing, however, I determined to stroll about and examine the town.Borrow.
And that she should force me, by the magic of her pen to mentally acknowledge, albeit with wrath and shame, my own inferiority!Corelli. Such things as our modern newspapers chronicle, albeit in different form.Corelli. It is thought by experts that there could be no better use of the money, albeit the best American colleges, with perhaps one exception, have very strong staffs of professors at incredibly low salaries.Times. 'Oxoniensis' approaches them with courage, his thoughts are expressed in plain, unmistakable language, howbeit with the touch of a master hand.Daily Telegraph.
Living in a coterie, he seems to have read the laudations and not to have noticed aught else.Times. Hence, if higher criticism, or aught besides, compels any man to question, say, the historic accuracy of the fall...Daily Telegraph. Many a true believer owned not up to his faith.Daily Telegraph. The controversy now going on in your columns anent 'Do we believe?' throws a somewhat strange light upon the religion of to-day.Daily Telegraph. It is because the world has not accepted the religion of Jesus Christ our Lord, that the world is in the parlous state we see it still.Daily Telegraph. A discussion in which well nigh every trade, profession and calling have been represented.Daily Telegraph. Why not? Because we have well-nigh bordering on 300 different interpretations of the message Christ bequeathed us.Daily Telegraph. It is quite a common thing to see ladies with their hymn-books in their hands, ere returning home from church enter shops and make purchases which might every whit as well have been effected on the Saturday.Daily Telegraph. How oft do those who train young minds need to urge the necessity of being in earnest...Daily Telegraph. I trow not.Daily Telegraph. The clerk, as I conjectured him to be from his appearance, was also commoved; for, sitting opposite to Mr. Morris, that honest gentleman's terror communicated itself to him, though he wotted not why.Scott. I should be right glad if the substance could be made known to clergy and ministers of all denominations.Daily Telegraph. So sordid are the lives of such natures, who are not only not heroic to their valets and waiting-women, but have neither valets nor waiting-women to be heroic to withal.Dickens.
An I had not been a thief, I could not have painted me your face. Put me your hand into the corner, and see what ye find there. Bring me him down like a ripe apple. And keep ever forward, Master Shelton; turn me not back again, an ye love your life. Selden, take me this old shrew softly to the nearest elm, and hang me him tenderly by the neck, where I may see him at my riding. Mark me this old villain on the piebald. 'Sirrah, no more words,' said Dick. 'Bend me your back.' 'Here is a piece of forest that I know not', Dick remarked. 'Where goeth me this track?' 'I slew him fair. I ran me in upon his bow,' he cried. 'Swallow me a good draught of this,' said the knight.
But the Captain, who, of course, lacks bowels of mercy for this kind of thing, says that if he had been Caesar, 'Caius would have got the great chuck. Yes, madam, I would have broke Mister Caius on the spot'.Crockett. But if you once go in for having a good time (as Miss Anne in her innocence used to remark) you must be prepared to...Crockett. ...as all girls love to do when they are content with the way they have put in their time.Crockett.


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Once again tell us which jurisdictions are having a hard time dealing with the NCC and who feel fine with the our favorite words "ecumenical dialogue"? ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I ask short questions because the pros on this board are my teachers (sort of).
Alex we all pray that you will be able to better control yourself in the future and not sin so profusely But seriously I think that even Orthodox bishops who like to engage in 'Ecumenical dialogue' should be concerned about this. Orthodoxy is really not being given a voice at all in the NCC. Rather it is being gaged and trotted out for PR reasons like I said before. I think these are three good articles http://www.orthodoxytoday.org/articlesprint4/CouretasNCCP.shtml http://www.orthodoxytoday.org/articles4/JacobseNCCStalinists.shtml http://www.orthodoxytoday.org/articles4/JacobseCubaVisit.shtmlIf you want to know who is in the NCC heres the page http://www.ncccusa.org/members/index.html Even the Serbs and Russians are still there! Who is not in the NCC? Well the Jerusalem Patriarchate, ROCOR, the Holy Synod in Resistance, the Genuine Orthodox Church, and other Old Calendarists. The reason why I started this discussion is that I want to know why the SCOBA churches have remained, what recent news/developments do you know about, what do you think about this situation, and is there anything that the laity can and/or should do to try and get the bishops to wake up and smell the garbage?
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Art is subjective, but we think we can objectively say that Massachusetts has the best art in the entire solar system. After all, it's home to the Museum of Fine Arts, Boston, one of the world's most impressive collections of fine art; Mass MoCA, the country's most fertile site for large scale new art; and the "small but big" Worcester Art and Fitchburg Art Museums. Plus, there's a whole Museum of Bad Art, and one that's free if your name is Isabella. Wake up your soul at the Jacob's Pillow dance festival, catch yourself clapping inappropriately loud for the world famous Boston Symphony Orchestra or banging your head (in a good way) in the birthplace of hardcore punk. And don't leave without experiencing some drama (also in a good way) at one of our amazing theaters, from The Mahaiwe Performing Arts Center in The Berkshires to Worcester's majestic Hanover Theatre to Boston's storied theater district. You can also visit the Massachusetts Cultural Council website for more information on the arts in Massachusetts.
Explore the Massachusetts Masterpiece Trail
Sign up to receive emails about arts and culture.
Shakespeare & Company, Lenox
Cyclorama, Boston
Cushing House Museum
Federal mansion (1808); paintings, furniture, carriage house, and garden. more+ 1 saves
Custom House Maritime Museum
The Custom House Maritime Museum is gateway to the rich maritime heritage of Newburyport, the eastern seacoast's first major commercial... more+ 4 saves
Cushing House Museum
98 High St.
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Custom House Maritime Museum
25 Water Street
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I had intended to use this space for my annual tongue-in-cheek review of the Farmer's Almanac. I'll get to that later.
I'm not feeling particularly whimsical. I spent much of the past week watching a horror I could never imagine. Perhaps the world has endured worse natural disasters than the tsunami that devastated coastlines from Sumatra to Thailand to Sri Lanka and all the way over to Somalia on the East African Coast, but in all the reading I've ever done, all the news reports I've listened to or watched, I've never heard of one that bad. At last count, as many as 155,000 people were dead and experts expect disease, malnutrition and un-treated injuries to push that total nearer 200,000.
The first pictures televised, with waves crashing over four-story buildings, inspired awe at the power of nature. And then they showed the aftermath: people, holding onto their children as best they could, clinging to anything that offered some hope of salvation. I watched in absolute horror a small group of people cling to a rapidly disintegrating building as torrential waters, as if guided by malicious intent, tried to pluck them from safety. And, by ones and twos, they lost their grips and disappeared into the maelstrom.
I heard stories of parents having to choose which child to hold onto and which to give up to the flood. I can't imagine making that decision, knowing that I couldn't keep more than one child afloat and that if I didn't turn one loose all would die. No one should ever face that choice.
In one country, more than 40 percent of the dead are children. That's almost half a generation lost.
I watched as family members desperately searched for loved ones and as desperately mourned when they discovered them among the dead. I can't begin to imagine the grief.
A doctor expressed intense regret and frustration that lack of transportation prevented him from getting to areas where severely injured people desperately needed his skills. And he had to wait knowing that delay meant more death.
Several groups on small islands had to fend off crocodiles washed up with the waves.
I heard stories of remarkable survival, a family floating on the tide in their car until they hit dry ground, a modern day ark perched finally on a convenient Ararat.
A fisherman rode the biggest wave a mile or more inland, somehow avoiding trees, buildings and other obstacles that would have smashed him.
And people stopped to help each other, pulling them out of the raging waters, helping them find shelter, food and medical attention. Human kindness finds ways to express itself even in the worst of tragedies.
When the water finally receded, debris — including thousands of corpses — littered the streets; buildings were in shambles; landscapes devoid of vegetation.
I'm not a particularly generous person, but I was moved to donate something to help relieve what must be the greatest suffering I have ever seen. My wife suggested we double my effort. "We can afford it," she said.
I was glad that the United States added a zero to the initial $35 million pledge of support and I hope they add more. We can afford it.
These unfortunate people, many of whom had very little to begin with, will never recover from this disaster. How could they? But they will get on with life. And those of us fortunate enough to have plenty should help all we can.
Some were shown picking through the rubble, all that was left of their homes, searching for familiar items, mementos, perhaps family heirlooms. And many said they would start over as soon as they could.
"This is home," one man said. "What else can we do?"
e-mail: email@example.com


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Wow, what an epic weekend of NFL football! The Baltimore Ravens and Denver Broncos got things off to a bang on Saturday by playing one of the most thrilling football games I have seen in a long time. Both teams left everything they had on the field in Denver Saturday night and it's a shame that someone had to lose that game. The Ravens are a team on a mission and are very well coached and seem to have gotten their offensive issues worked out in a major way when it matters most. They definitely showed a lot of heart and determination in persevering last Saturday.
The San Fransisco 49ers and Green Bay Packers game was an exciting game for almost three quarters before the 49ers were able to pull away for an impressive victory. The 49ers are another team that struggled offensively at various times this season but seem to have gotten that issue solved and may be able to ride it all the way to the Super Bowl.
The Seattle Seahawks dug a deep hole for themselves in Atlanta during the first half of their game with the Falcons on Sunday and almost managed to climb all the way out of it. The Falcons had to hang on for their lives to hold off the Seahawks in what started out being a blowout but ended in dramatic fashion. In my opinion, the Falcons are going to have to play much better defense over the entire four quarters to beat the 49ers next Sunday.
The final game of the weekend went pretty much as I expected it to go. The New England Patriots are a veteran team who are used to being in these pressure situations and simply had too many weapons they could use against the Houston Texans who tried to make a game of it but simply didn't have enough firepower or the defensive capabilities to overcome the Patriots. The Texans are developing into an excellent team but need to address their defensive shortcomings during this off season if they want to become the well rounded team they need to be to win an AFC championship.
While the Broncos and Ravens were finishing up their epic battle on Saturday the Missouri Tigers basketball team was laying a giant egg in Oxford, Mississippi. Every college basketball team seems to play one clunker a year and hopefully Missouri got theirs out of the way last Saturday against Ole Miss. Missouri could do nothing right and really should have just stayed home. They looked horrible offensively and not much better defensively. I understand Lawrence Bowers their leading scorer and team leader was out with an injury but that is no excuse for shooting air ball after air ball and failing to get back on defense or really even attempting to play it for the most part. It was a pathetic effort by a team who is much better than that against a team who quite honestly isn't very good. Missouri has now gotten their first win and loss in the SEC out of the way in less than a week and hopefully can get back to playing the way they are supposed to play on Wednesday when the Georgia Bulldogs come to Columbia.
The Truman State basketball teams split their games with Emporia on Saturday at Pershing Arena. The women looked very impressive in putting away a very good Emporia State team to notch their 12th victory of the season against only two losses. The men did everything but win as they absorbed another tough loss against a very good Emporia State team. Both teams are on the road Wednesday as they travel to Topeka, KS to play Washburn.
The Kirksville High School Tigers basketball teams also split a double header over the weekend as the girls easily defeated Highland on Friday night while the boys struggled offensively and came up on the short end of their game with Highland.
Congratulations to the Kirksville High School wrestling team on an outstanding performance at the Centerville Big Red tournament this past Saturday. They hit the mats again on Tuesday for a home meet which would be an excellent opportunity for you to get out and see some excellent high school wrestling.
We will be back on Wednesday with our midweek blog with various musings on things in the sports world we haven't had the time to talk about with everything else that has been going on. Thanks as always for supporting this blog and I hope wou will do the same for the other blogs on this site as well.
Have a terrific Monday!


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Brewing processes and methods. How to brew using extract, partial or all-grain. Tips and tricks.
Moderator: slothrob
3 posts • Page 1 of 1
I normally use party pigs, but now have a beer that needs atleast another month to mellow. I also bottle directly from the secondary, so I throw the cornsugar in the pigs and go. Due to past infections I have cut out about three transfer steps. Anyhow, how much cornsugar per 16 oz. bottle should I use.
- maltvault
- Light Lager
- Posts: 42
- Joined: Tue Jul 25, 2000 12:01 pm
Some math
Typically when priming a 5 gallon batch, 3/4 cup of corn sugar is adequate for priming. You can get about 40 16 oz. bottles out of a full 5 gallons. This breaks down to about 1/4 cup for every 13 1/3 bottles, 1 tablespoon for every 3 1/3 bottles, and a little over 1 teaspoon per 16 oz. bottle
- mich
- Posts: 6
- Joined: Sun Jan 09, 2000 10:45 pm
Bottling now
I am putting that Cream Stout in the bottles now, thanks for the help. I will use exactly one teaspoon 'cause I belive there is plenty of yeast left. It should be good in about 2-3 weeks, I'll let you know.
Malt Vault
Malt Vault
- maltvault
- Light Lager
- Posts: 42
- Joined: Tue Jul 25, 2000 12:01 pm
3 posts • Page 1 of 1
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text: Download 3D wallpaper in high quality as costly free. We have a great collection of the 3D Hd wallpapers. You will be able to catch so many of the amazing wallpapers of the 3D wallpaper straight away into the high definition mode. Feel free to make the use of these excellent 3D high definition wallpapers on the platforms of the PC, Laptops as well as i Pad, i Phones and so many more mobile devices.


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Local salons raise $220 for cancer
Beauty shops around Boonville are competing to see who can raise the most funds for Cooper County Relay for Life in 'Cutting for a Cure.' The funds will be used to help fund the research for a cure for the disease.
Cooper County Relay for Life Committee member Courtney Ray, who works at Uptown Girlz Hair Company, set up the event, which asked for donations at beauty shops around Boonville. The shops sold footprints for $1 from March 25-April 25. The footprints were displayed with the donating individual's name on them. Ray said 90 percent of the local shops participated in the event, including Uptown Girls, A Touch of Claas, Headlines, Intensive Hair, Designing Women, Show Me Cuts, Smart Styles and Rockn' Hair.
"I thought it would be great to get us all together to raise money for cancer research," Ray said.
Ray approached Linda Claas, owner of A Touch of Claas, about the fundraiser. Claas said she thought it was a great idea, especially when the funds are spent helping out each other.
"I wanted to help provide funds for a cure. I have had several family members who have died from cancer," Claas said.
The shops raised a total of $220. Uptown Girlz collected the most out of all the shops with a total of $97.
Ray said she was happy with the outcome of the event.
A plaque will be awarded for their efforts at the Cooper County Relay for Life, which will be held at the Boonslick Heartland YMCA.


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I was at work this morning, phone was fine. Then I used it again and the Home button was firm. Little travel, spongy, and no click. Still works but very awkward.
If I take it to the Telco store I got it from, 2 week wait. We have no Apple stores in NZ. I called Apple, a guy in central Texas answered. Australia was too early to answer. He arranged an express replacement. Waited hours for the email confirmation. Tonight I get another email. Its being despatched from Sydney by TNT, its at TNT, e.t.a. is tomorrow! Its probably in the air from Sydney to Christchurch.


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Multimodal Neuroimaging of Treatment Effects in Adolescent Mania
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT00893581
Recruitment Status : Completed
First Posted : May 6, 2009
Last Update Posted : May 19, 2016
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Specific Aim 1: To determine the effects of treatment with quetiapine or lithium on brain activation in adolescents. The investigators will use functional magnetic resonance imaging (fMRI) to examine brain activation during an attentional task.
Specific Aim 2: To determine the effects of treatment with quetiapine or lithium on neurometabolite measures, early in their illness course. The investigators will use 1H-MRS to identify myo-inositol (mI), N-acetyl aspartate (NAA), and glutamate (Glu) levels in prefrontal ALN regions.
Specific Aim 3: To determine the relationships among the changes in brain activation and neurometabolite measures, as well as symptomatic improvement in manic adolescents.
|Condition or disease
|Mania Bipolar Disorder
|Drug: Quetiapine & Placebo Drug: Lithium and Placebo Other: Healthy Controls
|Not Applicable
Hypotheses 1 & 2 predict that following 6 weeks of treatment with lithium or quetiapine, manic adolescents who demonstrate symptomatic improvement will exhibit normalized (decreased) VLPFC and ACC activation and increased activation of compensatory posterior attentional brain areas as well as normalization of VLPFC and ACC neurometabolite measures (increased NAA and decreased Glu levels) compared with those who do not experience symptomatic improvement and healthy adolescents.
Hypothesis 3 predicts significant associations between fMRI activation changes (i.e. decreased activation in VLPFC and ACC ROIs and increased activation in the posterior attention ROI) and MRS changes (increases in NAA and decreases in Glu levels in the VLPFC and ACC) for patients who exhibit symptomatic improvement with either treatment.
Hypothesis 4 predicts that decreases in mI levels at 1 week will be associated with lithium, but not quetiapine, response at endpoint.
In contrast, Hypothesis 5 predicts higher baseline Cho levels will be associated with quetiapine, but not lithium, response at endpoint.
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|169 participants
|Intervention Model:
|Parallel Assignment
|Triple (Participant, Care Provider, Investigator)
|Primary Purpose:
|Official Title:
|Multimodal Neuroimaging of Treatment Effects in Adolescent Mania
|Study Start Date :
|March 2009
|Actual Primary Completion Date :
|February 2016
|Actual Study Completion Date :
|March 2016
Active Comparator: 1--Quetiapine & Placebo
Quetiapine & Placebo in the place of Lithium
Drug: Quetiapine & Placebo
Bipolar adolescents will be initiated on 100 mg per day of quetiapine (or placebo) and 30 mg/kg (maximum starting dose of 600 mg twice daily) of lithium carbonate (or placebo), depending on randomization assignment. Patients will be given placebo for the medication to which they were not assigned. Quetiapine will be adjusted based on tolerability and response to a target dose of 400-600 mg and lithium will be adjusted to a target dose based on achieving a serum level of 1.0-1.2 mEq/L.
Active Comparator: 2-- Lithium & Placebo
Lithium & Placebo in the place of Quetiapine
Drug: Lithium and Placebo
Bipolar adolescents will be initiated on 100 mg per day of quetiapine (or placebo) and 30 mg/kg (maximum starting dose of 600 mg twice daily) of lithium carbonate (or placebo), depending on randomization assignment. Patients will be given placebo for the medication to which they were not assigned. Quetiapine will be adjusted based on tolerability and response to a target dose of 400-600 mg and lithium will be adjusted to a target dose based on achieving a serum level of 1.0-1.2 mEq/L.
Placebo Comparator: Placebo
Sugar Pill (Placebo) given to mimic drug
Other: Healthy Controls
Healthy control (patients given placebo -- sugar pill intended to mimic drug)
- The purpose of this study is to use magnetic resonance imaging (MRI) to examine brain structure, function and chemistry in people with Bipolar I disorder (manic or mixed episodes) who are being treated with either quetiapine or lithium. [ Time Frame: 6 weeks ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|12 Years to 17 Years (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion/Exclusion Criteria
Inclusion - Bipolar Disorder Subjects:
- DSM-IV-TR12 criteria for bipolar disorder, type I, manic or mixed episode, diagnosed by the Washington University in St. Louis Kiddie Schedule for Affective Disorders and Schizophrenia (WASH-U-KSADS)166,101,102-103,104-105,108
- Baseline YMRS112-114 score > 20;
- Ages 12-17 years 11 months old;
- Fluent in English;
- Provision of written informed consent by a legal guardian and written assent by the subject;
- Tanner scale stages III-V167, in order to include only post-pubescent subjects and minimize brain changes associated with the onset of puberty;168-169
- Less than 2 years from onset of bipolar disorder, defined by age at onset of first DSM-IV-TR affective episode (mania, hypomania, depression or mixed), to establish that our sample is early in their illness course;
- No prior psychiatric hospitalizations, <3 months of lifetime psychotropic medication exposure (with the exception of psychostimulants, since excluding patients with psychostimulant exposure would significantly limit the generalizability of our findings), and no active psychotropic medication during the week (72 hours for psychostimulants and benzodiazepines) prior to the index assessment (no treatment with fluoxetine during the prior month). Please note that patients will NOT be taken off medications for the purpose of this study; instead, this criterion is to exclude subjects receiving treatment at the time of index assessment;
- Does not have a history of intolerance or non-response to lithium or quetiapine;
- Manic or depressive symptoms do not result entirely from acute medical illness or acute intoxication or withdrawal from drugs or alcohol as determined by medical evaluation and rapid symptom resolution;
- No lifetime DSM-IV-TR diagnosis of post-traumatic stress disorder (PTSD), since PTSD has been associated with abnormalities in prefrontal NAA and function170-171,172. Furthermore, bipolar patients with co-occurring PTSD are less likely to respond to lithium monotherapy, and often need a serotonin specific reuptake inhibitor (SSRI) as adjunctive treatment to a mood stabilizer.173,174 ;
- If female and of child bearing potential, agrees to use one of the following method of birth control: complete abstinence from sexual intercourse, barrier (diaphragm or condom), or oral/injectable contraceptive.
Inclusion - Healthy Controls:
- Ages of 12-17 years and 11 month;
- No history of any DSM-IV-TR Axis I disorder (nicotine dependence is permitted);
- No first- or second-degree relatives with an affective or psychotic disorder;
- No medications with central nervous system effects within 5 half-lives;
- Fluent in English;
- Tanner stage III-V;
- Provision of informed consent and assent.
Exclusion - Bipolar Subjects & Healthy Controls:
- Contraindication to an MRI scan (e.g., braces or claustrophobia);
- An unstable medical or neurological illness that could influence fMRI or MRS results;
- IQ < 70, as determined by The Wechsler Abbreviated Scale of Intelligence (WASI) ;
- A positive pregnancy test;
- A history of major medical or neurological illness or a significant episode (> 10 minutes) of loss of consciousness;
- Any lifetime DSM-IV-TR substance use disorder (nicotine dependence is permitted);
- A lifetime DSM-IV-TR diagnosis of any pervasive developmental disorder;
- The patient lives >100 miles from the University of Cincinnati or is not able to attend follow-up visits.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00893581
|United States, Ohio
|University of Cincinnati
|Cincinnati, Ohio, United States, 45219
|Principal Investigator:
|Melissa DelBello, MD
|University of Cincinnati
|Responsible Party:
|Melissa Delbello, Professor, University of Cincinnati
|ClinicalTrials.gov Identifier:
|NCT00893581 History of Changes
|Other Study ID Numbers:
DelBello MM NeuroImaging Study
|First Posted:
|May 6, 2009 Key Record Dates
|Last Update Posted:
|May 19, 2016
|Last Verified:
|May 2015
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
Keywords provided by Melissa Delbello, University of Cincinnati:
Additional relevant MeSH terms:
Bipolar Disorder
Bipolar and Related Disorders
Mental Disorders
Quetiapine Fumarate
Lithium Carbonate
Antipsychotic Agents
Tranquilizing Agents
Central Nervous System Depressants
Physiological Effects of Drugs
Psychotropic Drugs
Antidepressive Agents
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Antimanic Agents


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Modern wall lighting is available in a wide selection of fixture types and design. In order to choose one, you have to consider which position it will be installed. If it is for reading, then it must be placed in a position that light is directed to the page. If you want a wider range of light, then you have to install them higher.
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Modern wall lighting comes in a variety of styles and colors finishes and often has matching ceiling lights. Browse through the internet and find the style perfect for you.


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Operation Swordbreaker
Operation Swordbreaker is the second mission in the single-player campaign of Battlefield 3.
Protect Chaffin from the soldiers in the street in Operation Swordbreaker
Secondary training level slash first stage. Just follow the fireteam and do everything they tell you to do. After you investigate the vehicle IED, you will have a horde mode fight until you reach the vehicular weapon.
Parking Lot Ambush[edit]
Rescue Chaffin (QTE) and use the ammo box to infinite stock your grenades for the lulz. As long as you stay next to the replenishment box, you never run out of ammo. You will also have moderately secure cover to hide from enemy fire. Down the RPG carrying fighters and clear the area of the remaining enemies.
Sprint past the hallway, kill the PLR fighters and get to the roof. Stay low, crawl to the corner and take the SMAW to kill the sniper.
Protect Doc Holliday[edit]
The Medic/Corpsman with the callsign, Doc Holliday, requires cover fire to CASEVAC Chaffin. Waste the enemies across the street and rooftops before they waste you.
Investigate Viper Team[edit]
Locate Viper team past the ammo crate hallway. Trace the red wire into the building and get a QTE vs a PLR ambush fighter. The buttons for the Quick Time Event are always the same, so you can remember the inputs and smash the guy's face in.
Beat Off the PLR[edit]
Engage and hold back the PLR by using the marksman rifle (not the LMG ... unless you like getting shot and killed on hard) until you can retreat to the HMV and man the turret. Mission ends after you drill everyone and the enemy tide stops.
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