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This article is a collaboration between MedPage Today® and:
The high resolution of cardiac MR imaging revealed structural and functional damage to the hearts of obese adolescents prior to bariatric surgery and reversal of that damage after surgery, a small study found.
At baseline, the 10 obese adolescents in the study -- with a mean body mass index of 50 kg/m2 -- had evidence of heart enlargement, with a mean left ventricular (LV) mass of 122 g versus 101 g in normal-weight controls (P=0.02), according to Marc P. Michalsky, MD, and colleagues from the Ohio State University College of Medicine in Columbus.
"Relative to subject-specific expected normal weight values, the obese patients averaged an additional 20 g of LV mass," a result that was "quite striking," they wrote in the January issue of the Journal of Pediatric Surgery.
Researchers had follow-up imaging data on five patients whom they tracked because of their positive adenosine stress tests prior to surgery.
Follow-up imaging at a mean of 9 months showed reductions in LV mass in the range of 2 to 12 g in four patients, while three had "complete resolution" of the sub-endocardial ischemia and the remaining two showed a "marked improvement."
"The primary observations we want to present in this publication are that extremely obese adolescents have enlarged hearts at rest and, in many cases, stress-induced perfusion deficits, which are hallmark characteristics of adult heart patients," Michalsky told MedPage Today. "Thus far, it appears that the sub-endocardial ischemia, when present, can be reversed following bariatric surgery and may be more dynamic or reversible during weight loss."
A larger study presented at the 2009 American Heart Association meeting by Holly Ippisch, MD, of Cincinnati Children's Hospital, and colleagues also found reverse remodeling after bariatric surgery in severely obese adolescents at 6 months that persisted out to 2 years.
Michalsky and colleagues emphasized the importance of using cardiac MRI in very obese adolescents because of its ability to deliver high-fidelity images of cardiac structure and function, particularly compared with transthoracic echocardiography.
Cardiac MRI is "not impeded by extensive thoracic fat deposits and chest wall expansion unlike acoustic imaging methods," they wrote.
They also noted that many cardiac conditions in adults are associated with chronic LV enlargement including chronic congestive heart failure, acute MI, arrhythmia, stroke, and sudden cardiac death.
But none of these adolescent patients showed any signs of scarring, "a feature that is widely believed to be irreversible and predictive of heart failure and sudden death in the adult population, [which] supports the hypothesis that 'early' intervention [such as] adolescent weight-loss surgery may have advantages with regards to cardiac recovery," they wrote.
In this preliminary study, the researchers retrospectively analyzed data from 10 severely obese adolescents (nine girls, mean age 17).
Patients had undergone either Roux-en-Y gastric bypass or laparoscopic adjustable gastric banding at Nationwide Children's Hospital in Columbus, Ohio, in 2008.
All patients had at least one of the following comorbid conditions: hypertension, dyslipidemia, acanthosis nigricans, insulin resistance, and obstructive sleep apnea. Two girls had polycystic ovary disease, which has been shown to be associated with obesity.
Along with greater LV mass, the obese patients had greater LV end-diastolic volume at baseline relative to expected normal-weight values: 156 mL versus 109 mL (P=0.001).
Again, researchers noted the "striking" 47 mL difference between what would be the expected normal LV end-diastolic volume and what they found in the obese patients.
However, they did not identify a consistent pattern of change in LV end-diastolic volume, "most likely secondary to the extremely low number of subjects that underwent follow-up analysis," Michalsky said.
Obesity also affected LV ejection fraction, as the patients had a mean value of 61% compared with 71% for expected normative values.Functionally, all patients were at a disadvantage as they averaged a 50% lower myocardial perfusion reserve index compared with the calculated expected normative values.
Researchers wondered if there were markers they could link with the structural and functional changes. Their analysis found that an increase in LV mass was directly correlated with systolic blood pressure (r=0.67, P=0.05).
This analysis also showed a correlation of the myocardial perfusion reserve index with levels of fasting serum insulin. Specifically, when the perfusion reserve index decreased, serum insulin increased (r=0.75, P<0.01). The same inverse relationship occurred for another marker of insulin resistance, HOMA-IR (r= -0.75, P<0.01). At baseline, eight patients had elevated HOMA-IR levels.
There were no other statistically significant relationships that could be associated with the structural and functional changes in these individuals.
These data need to be confirmed in larger studies, the researchers said.
They also noted that the study is limited by its retrospective nature and small patient sample.
From the American Heart Association:
- Bariatric Surgery and Cardiovascular Risk Factors
- Nontraditional Risk Factors and Biomarkers for Cardiovascular Disease: Mechanistic, Research, and Clinical Considerations for Youth
- Childhood Obesity Research Summit
The authors did not provide information on conflicts of interest.
- Reviewed by Robert Jasmer, MD Associate Clinical Professor of Medicine, University of California, San Francisco and Dorothy Caputo, MA, BSN, RN, Nurse Planner


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Irish American homicide detective, Edward Foy, has witnessed Irish police being intimidated on the street by intoxicated offenders. He believes the time has come for Irish police to carry guns.
The 39-year U.S. law enforcement veteran explained what he had witnessed on St. Patrick's Day in Dublin this year, in an column on Journal.ie. While heading back to his hotel off Grafton Street he and his colleague, who were also on vacation, spotted a group of police who were being surrounded by "intoxicated youthful offenders".
Foy said "I watched, thinking "I hope these thugs are not armed with a gun or edged weapon." Because when you go up against multiple individuals who are under the influence, it's dangerous. And the only weapon they have is a nightstick. In my opinion, arming these officers with nothing but a baton in these conditions is simply reckless."
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After observing the situation for a number of minutes Foy and his buddies stepped in. He said "The officers knew we were cops – and we just basically stood around the two of them. It could have been really ugly; but there were four of us, and we're above average size, and we had their back. So when the crowd was dispersed they thanked us and we on about our business, they went about theirs."
The homicide detective said the difference between being armed with a nightstick or a gun is "an unwritten respect".
He said "If I'm going into a confrontation with seven, eight individuals, and I'm armed, they know it. So they're going to take a second thought about getting into a confrontation. But these thugs, they knew that the maximum protection of these two garda officers was an expandable baton. If I'm a thug in that situation, I've got to think I like my odds. But if I have to deal with an officer who's got a firearm, I'm going to think twice."
Foy calls to mind a horrific recent incident which could have ended differently had the police officer been carrying a gun. He said "Recently there was a case of a garda who was attending a domestic disturbance, and he had boiling oil thrown in his face. Now when I look at that, I think: Would that incident have brought about the use of a firearm? Probably not. But would that person have thrown the grease knowing that the officer was armed? That's the question."
He says the fact that Irish police are going on their daily beat with limited resources is "mind boggling" to him and his colleagues. He explained "I follow the Irish media, and in my estimation there has been a serious escalation in gun crime since six or seven years ago. It's reckless to have unarmed officers dealing with that kind of situation."
He continued I really feel sorry for the Irish officers, in a way. Because they don't have that protection. I know that a lot of the higher level guys dealing with organized crime are armed. But I also know that the street-level people are your first line of defense. When you see the stories about these guys being injured, or dying – it's appalling. They've got families, they've got children. If I'm an officer, and I've got four or five kids, I want to go home to them every night."
Foy has worked in law enforcement in the United States for 39 years and regularly visits Ireland. He currently works at the Manatee County Sheriff's Office, in Florida. He told Journal.ie "My great-grandparents on both sides were born in Ireland, one in Donegal and the other in Mayo, and I regularly visit Ireland with some other officers of Irish heritage."

subset: commoncrawl


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Hello: Dear Diary
On the right is something I made from this week's Blockham's by Six Zero.
The left is a screen-cap from the pinnacle of awesome. Threads existing in the shot are as follows: WOOOO-HOOOOO!; Hello: Chris Fox; MUPPETS!!!!!!!; Sullinger: post-game words to Burke; Hello: Taco Charlton; official greatest day of ever thread; Ozone: Meyer > Hoke on Recruiting Trail = Egg in Face; The Announcers; Brady Hoke; Senior Night Video?; Life, in General; What just happened???; and Super Saturday (2-18-2012) Recap. That last by YakAttack has the play-by-play for everything that went down but here's Saturday:
- 12:00 p.m. Football: Kyle Bosch commits
- 1:00 p.m. Lacrosse: Begins first-ever road game as varsity (would lose to PSU 16-9)
- 1:05 p.m. Football: Wyatt Shallman commits
- 1:55 p.m. Track & Field: Trio of Wolverines finish first at Silverston Invitational.
- 2:25 p.m. Football: Jourdan Lewis commits, whiddle-guy Cass Tech CB mantle deployed
- 2:25 p.m. Football: David Dawson commits.
- 3:36 p.m. Baseball: Logan McAnallen pitches 2 scoreless innings to preserve Bobby Brosnahan's gem (7.0 innings, 4 hits, 1 run), and Michigan beats Setaon Hall 2-1.
- 4:21 p.m. Softball: Freshman LHP Haylie Wagner completes shutout of No. 22 Kentucky
- 7:25 p.m. Hockey: A.J. Treais scores in OT to beat Northern Michigan and sweep weekend series.
- 9:20 p.m. M Gymnastics: Season-high 345.700 score hands Ohio State their first loss
- 9:39 p.m. Softball: Freshman RHP Sara Driesenga completes shutout of FAU
- 11:00 p.m. M Basketball: Michigan upsets No. 6 Ohio State 56-51
- 11:01 p.m. Kate Upton: Kate Upton is all Kate Upton.
- 11:05 p.m. Football: Chris Fox commits
- 11:30 p.m. Football: Taco Charlton commits.
- ~11:59 p.m. Jake Butt and Logan Tuley-Tillman enter REM sleep, where their dreams are invaded by GHOST OF NINJA RECRUITING SHANE MORRIS, who gives them helmets with wings and beckons they fly with him to the land of a thousand trees.
Tennis lost to Notre Dame (BlueDragon's comprehensive paume update) at some point in there, but you get the idea. Lets_Go_Blue put up an imaginative photo recap of the weekend in the diaries. Posbang thread? Posbang thread.
I'm So Softball Right Now You Guys! The shutout streak is now up to four games, thanks to Michigan's magnificent freshmen starters. I suddenly feel like doing lines!
|Sara Driesenga
|Haylie Wagner
Haylie is a clone of Jordan Taylor (even played for the same league in Orange County) and is the crafty lefty complement to Driesenga. As such Wagner wasn't supposed to have a lot of strikeouts but, uh, well look above. The other shutout was Junior Stephanie Speierman, who was 18-1 last year with a 1.88 ERA in 122 innings. I had to look at several other top teams to convince myself these rotational riches are as ridiculous as they look. They are.
Ensuing Diaries
The Quantum of Verisimilitude. After watching smart people commit to Hoke in droves over the weekend, Urban Meyer, Legendary Recruiter™ put up a sign so full of deceit people thought he was running for office (hyuk!). Accordingly, people who take twit pics of things made by twits at face value sent it around the internet. Enter Diarist of the Week Michael Scarn, who took the crucial step of, you know, a few cursory Googles to pull the real numbers from the teams' respective media guides.
Yes, our readers with
Office Space The Office joke names are better at research than whoever's doing the signs for Ohio State's head coach. I'm sure this has nothing to do with which school is a better research institution.
Which school is the better research institution? U.S. News & World Report has its new rankings for "Worlds Best Universities" and M is 14th in the world, 10th in the nation, and 2nd among FBS schools. Ohio State (111th in world, 35th in U.S.) isn't so hot, though they'd still be middle of the Pac 12, upper quarter of the ACC, and only behind Texas-Austin anywhere else. The Big Ten is back ahead of the Pac, more because of the Oregon schools than what they added. Other bits of interest I put in a table-tastic diary.
Every Goal Against Northern Michigan. This is
one of my favorite new regular column, a weekly picture-paging of M scoring by CenterIce. Since most of my hockey knowledge comes from watching Lidstrom, the one I was instantly nodding at was the scoring opportunity created by Merrill having an NHL head on his shoulders:
Head up the whole way Merrill gets the puck from Moffie and finds Deblois cutting through the middle.
The Northerners are all kinds of confused, obviously since the blueliner has closed his legs like he's in shot blocking position.
It's Aaaaaalive! The 2013 Offer List has been updated.
Etc. The Mathlete clarifies his maths, but this doesn't make sense unless you read Bill Connelly (of SBNation blog Football Study Hall)'s response to the Mathlete original. Video of last week's defeating of Ohio State, and the Sugar Bowl.
Best of the Board
Remember kids, helpful Google Maps reviewers should always get upvoted. Unfortunately this well-executed trolling has been found and restored back the THE College of Performing Bears.
When you search for directions to Ohio Stadium on Google Maps…oh I'll let you try it.
Etc. Salute to Percy Bates, retiring after more than two decades as the AD's faculty rep. HT Section 1.


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Yeah, let's do that.
Barry Eisler makes a great point (IMO) about author bios in a guest post on M.J. Rose's blog, titled "It's the Marketing, Stupid:"
Have you, as a potential customer, ever been moved to buy a book by when the author was born, or by where? Or by where she's living these days? "Holy smokes, this guy was born in Newark, sounds like my kind of writer." "Damn, she lives in Bakersfield? Gotta read this book."
Barry says some other smart things there, too. By the way, M.J. Rose's blog is named, "Buzz, Balls, and Hype." M.J., I salute you.
Work Awesome has an, er, awesome article on How to Create an Efffective and Engaging Bio Page. Here's an example of the nuggets in the piece:
Think about the impression you want people to have upon reading your bio and the action you want them to take. How can you craft a page that will shape these goals?
There's quite a bit of information in that post. Three snaps in a circle!
By the way, I'm still working on my bio, so feel free to critique it. Or post yours in the comments and offer it up for critique by anyone in the neighborhood!
Tags: Author Bios, Bios, In Living Color, Men on Books, Self-Promotion


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From Dodge City (6A), Holcomb (3A), Sublette (2A) and St. John (1A)
KSHSAA STATE TRACK QUALIFIERS DODGE CITY (6A) Boys regional champions – Bryce Sonday (discus, 160-2; shot put, 51-0 �), Oscar Carmona (800, 1:56.77; 1,600, 4:23.40). Other state qualifiers – Elder Colindres (800, second; 1,600, fourth), Victor Ortiz (pole vault, third), Tanner Flax (javelin, fourth), Tyler Trent (long jump, fourth), 4x400 relay (Colindres, Sterling Pike, Luis Cruz, Trent), 3:27.25. Girls regional champions – Summer Wilson (100 hurdles, 14.61). Other state qualifiers – Wilson (high jump, second; long jump, third), Katrina Roenfeldt (javelin, second; triple jump, second), Brekk Flax (100, third; 200, third), Chandra Sain (pole vault, third), Ciera Lampe (discus, third), Jessie Harshberger (400, fourth), 4x100 relay (Wilson, Harshberger, Dezera Johnson, B. Flax; second). FINAL SCORES OF CLASS 6A DODGE CITY REGIONALS BOYS – Garden City 109, Wichita South 85, Dodge City 77, Wichita Northwest 70, Maize 60, Wichita North 55, Hutchinson 51, Campus 48. GIRLS – Maize 154, Garden City 105.5, Dodge City 91.5, Wichita Northwest 71, Hutchinson 53, Wichita South 35, Campus 34, Wichita North 14. CIMARRON (3A) Boys state qualifiers –Tyrone Clark (high jump, second), Isaac Stanley (1,600, third; 3,200, third), 4x800 relay (Javier Trevino, Jonathan Martinez, Stanley, Cody Toothaker, fourth). Girls regional champions – Morgan Ediger (300 hurdles, 46.64), Eva Koopman (high jump, 5-7; long jump, 17-10). Other state qualifiers – Isabella Koopman (1,600, third; 3,200, third), Kari Blattner (3,200, third), E. Koopman (100 hurdles, fourth), 4x800 relay (Charise Friesen, I. Koopman, Ediger, Blattner, third), 4x400 relay (Friesen, Brynn Walker, Blatner, Ediger, fourth). FINAL SCORES OF CLASS 3A HOLCOMB REGIONAL BOYS – (top five) Phillipsburg 119, Holcomb 73, Cheney 64.5, Scott City 51, Hays TMP 49.5. 9. Cimarron 27. GIRLS – Hays TMP 89, Cimarron 68.5, Scott City 64.5, Cheney 58, Kingman 51, Norton 51. HODGEMAN COUNTY (2A) Boys state qualifiers -- Christian Schuler (3,200, third), Will Crabill (javelin, fourth). Girls regional champions – Brianna Bradshaw (400, 1:01.35). Other state qualifiers – B. Bradshaw (100 hurdles, second), Michelle Bradshaw (800, third), 4x800 relay (M. Bradshaw, Kelsey Lampe, Kelsey Cohoon, Shania Fitzpatrick, third), 4x400 relay (M. Bradshaw, Lampe, Cohoon, Fitzpatrick, fourth). KIOWA COUNTY (2A) Boys regional champions – Damien Odle (javelin, 177-11). Other state qualifiers -- Odle (high jump, second), David Perez (pole vault, third), Trever Powell (400, third), Caleb Davis (3,200, fourth), Creighton McDonald (200, fourth), 4x800 relay (Justin Boswell, Davis, Cody McVey, Powell, second), 4x100 relay (Keenan Behee, Landon Davis, McDonald, Powell, fourth). Girls regional champions – Heather Melton (100 hurdles, 16.91), Chelsea Oberle (triple jump, 36-2 �), Jansen Miller (pole vault, 8-6). Other state qualifiers – Melton (high jump, second), Katelynn Gamble (pole vault, second), Oberle (long jump, third), McKenzie Heft (javelin, third), Erica Bertram (400, third), Angela Liggett (discus, fourth), 4x100 relay (Gamble, Dena Liggett, Chelsea Oberle, Melton, second), 4x400 relay (Heidee Prosser, Riann Heft, Melton, Bertram, second). MEADE (2A) Boys regional champions – Trevin Wiens (100, 11.54; 200, 22.96; 400, 51.95), Hayden Borth (110 hurdles, 16.33; 300 hurdles, 41.52), Chris Hardaway (long jump, 22-2). Other state qualifiers – Morgan Davis (shot put, second; discus, second), Hardaway (300 hurdles, third; triple jump, fourth) Girls regional champions – Tarah Wiens (long jump, 17-5), 4x100 relay (Natalie Thompson, Jayden Rudzik, Amber Koons, Wiens, 52.37). Other state qualifiers –Wiens (200, third; 100, fourth), Kinzie Friesen (second, triple jump), Lauren Dewell (high jump, fourth), 4x800 relay (Jacqueline Clawson, Koons, Mackenzie Moshier, Hannah Miller, second). SOUTH GRAY (2A) Boys regional champions – Jake Peters (shot put, 48-8; discus, 145-4). Other state qualifiers -- Henry Friesen (shot put, fourth), 4x800 relay (Joshua Griebel, Zachary Tyler, Marco Ponce, Austin Koehn, third). Girls state qualifiers -- Dusty Watkins (shot put, second). FINAL SCORES OF CLASS 2A SUBLETTE REGIONAL BOYS – (Top five) Meade 94, Stanton County 90, Kiowa County 55, Elkhart 44, Wichita County 39. 6. South Gray 33, 13. Hodgeman County 17. GIRLS – (Top five) Kiowa County 92, Decatur 79, Meade 58, Ellis 54, Ness City 42. 8. Hodgeman County 38. 14. South Gray 1. ASHLAND (1A) Boys state qualifiers – Billy Day (800, third), Kole Konrade (high jump, fourth). Girls state qualifiers – Kara Reimer (400, second), Shelby Luerman (long jump, second; 200, third), Canaan Endicott (discus, third), 4x800 relay (Reimer, Sloan Kay, Maegahn Matson, Endicott, second), 4x400 relay (Luerman, Matson, Endicott, Reimer, third). BUCKLIN (1A) Boys state qualifiers – Brian Seacat (200, third), 4x100 relay (Blake Demoret, Brett Halling, Anthony Ledesma, Seacat, third). Girls regional champions – Gentry Stout (pole vault, 9-6). Other state qualifiers – Janae Price (3,200, third), Charlotte Davis (shot put, third). FOWLER (1A) Boys regional champions – Tem Shetley (400, 51.61), Ty Clark (javelin, 176-8), 4x400 relay (Shetley, Ty Clark, Taylin Bird, Efrain Estrada, 3:31.87). Boys state qualifiers – Jett Reese (shot put, fourth; discus, fourth), Shetley (200, second); 4x800 relay (Estrada, Clark, Bird, Joel Milford, fourth). INGALLS (1A) Boys state qualifiers – Joshua Irsik (100, fourth; 200, fourth). Girls state qualifiers – Kaisha Batman (triple jump, fourth). KINSLEY (1A) Boys regional champions – Nathan Frame (triple jump, 41-8). Other state qualifiers – Greg Newsom (shot put, second), Frame (800, fourth), Tyler Espinosa (300 hurdles, third), Gustavo Chavez (high jump, third). Girls state champions – 4x800 relay (Laurin Wagner, Brittany Gleason, Alexandra Herrman, Kate Gleason, 10:25.95). Other state qualifiers – B. Gleason (discus, fourth), Shaylee Meyers (javelin, third). MINNEOLA (1A) Boys state qualifiers – Jerrod Lies (pole vault, second). Girls state qualifiers – Jayda Minor (3,200, second; 1,600, fourth) PAWNEE HEIGHTS (1A) Boys state qualifiers – Jacob Hardiman (400, second). Girls state qualifiers – Megan Milch (high jump, second). SOUTH CENTRAL (1A) Boys state qualifiers – Stetsen Underwood (100, second; long jump, 20-0), Coby Lindsey (discus, second), 4x100 relay (Colton Herd, Underwood, James Cook, Nathan Brooks, second); 4x400 relay (Herd, Underwood, Cook, Brooks, third). Girls regional champions – Abby Gales (400, 1:01.73). Other state qualfiers – Kayla Olson (100 hurdles, second; 300 hurdles, third; 200, fourth), Micaela Jellison (shot put, fourth). 4x400 relay (Gales, Jellison, Reagan Bayne, Olson, fourth) SPEARVILLE (1A) Boys regional champions – Logan Durler (high jump, 6-3). Other state qualifiers – Seth Stroud (110 hurdles, third; 300 hurdles, fourth), Nathan Stein (110 hurdles, fourth). FINAL SCORES OF 1A ST. JOHN REGIONAL Boys – (Top five) Macksville 68, Pretty Prairie 62, South Central 56, Fowler 53, Stafford 46. 6. Kinsley 42. 9. Spearville 25. 11 (tie). Bucklin 16. 15. Ingalls 12. 17. Ashland 10. 18. Minneola 9. 19. Pawnee Heights 8. Girls – (Top five) Norwich 88, South Barber 49, Ashland 47.5, Satanta 44, Fairfield 39. 8. (tie) Bucklin, Kinsley 27. 13. Minneola 15. 18. Pawnee Heights 8. 20. Ingalls 6. 21. Spearville 3.5, 22. Fowler 3.


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Chemist by day, alchemist by night, this little redhead gained her Master's degree in Pharmacy by way of witchcraft and strong coffee.
Classic literature savant, death enthusiast, avid tea drinker and mother of rabbits, hailing from ye olde Albion.
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ATLANTA (AP) - December 19, 2013 --A truck overturned in metro Atlanta, spilling tons of hams onto an interstate ramp.
A local newspaper reports that the truck was hauling 40,000 pounds of hams Thursday around 4 a.m. when it overturned, spilling its cargo south of Atlanta. Authorities were working early Thursday to clear the ramp from Old National Highway to Interstate 85 southbound after the crash.
The cab of the truck was destroyed in the crash, which also caused a diesel fuel spill.
Truck driver, Rigo Vargas, said he was hauling the hams to Texas when he wrecked. He said he banged his head against the door when the rig flipped over, but wasn't seriously hurt.


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[Illinois] BioNanotechnology Seminar Series Fall 2011: Bio-inspired Microenvironments Regulate Cell Fate
Licensed according to this deed.
Published on
Epigenetic regulation of stem cell fate by intrinsic properties of the surrounding extracellular matrix (ECM), e.g. stiffness, organization, composition, etc., appears to be an important yet underappreciated contributor in development, disease, and aging. I will describe our efforts to develop biomimetic environments that mimic key intrinsic ECM properties to assess their contribution to regulating cell fate. For example, pre-cardiac mesodermal cells mature in to adult cardiomyocytes when their matrix mimics the 10-fold increase in stiffness that occurs naturally during development. Adult mesenchymal stem cells (MSCs) are particularly sensitive to small spatial stiffness gradients which can be found naturally in vivo; these gradients induce cell migration prior to differentiation and may in part explain MSC accumulation in stiffer regions of tissue interfaces. However, disease often inhibits these natural processes by creating an ischemic, fibrotic, and/or rigid environment. When matrix stiffness resembles the rigid fibrotic scar, micropatterning cells into specific morphologies can reset the cell to the appropriate contractility level required for myogenesis. Using these finding as design principles, we are engineering nano-patterned diblock copolymer foams to better guide cell differentiation in diseased microenvironments in vivo, but taken together these data at least imply that matrix properties, when displayed at the right time and place, are important regulators of cell fate.
Our research is focused on how cell behavior is directed by the extracellular matrix (ECM), a 3-dimensional fibrillar scaffold to which cells adhere, during development, disease, and aging. We use a variety of stem cell culture models (mouse and human; both embryonic and adult) as well as many animal models (fly, chicken, mouse, and rat) in which to study how ECM affects pathologies including myocardial infarction and muscular dystrophy. We have significant efforts to explore the molecular and cellular mechanisms of these non-growth factor-mediated mechanisms.
From Dr. Engler's faculty page
Cite this work
Researchers should cite this work as follows:
NanoBio Node, Zuhaib Bashir Sheikh
University of Illinois at Urbana-Champaign


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The disgrace of David Petraeus shouldn't damage the Central Intelligence Agency. Congress may summon or subpoena the former director and his paramour to testify about their relationship; it may lash them for the sins of pride and lust; it may even try to blame the death of an American ambassador in Libya on a distracted CIA. That would be a waste of time and breath.
But the Petraeus affair may well tarnish the Federal Bureau of Investigation. And maybe it should. There are more than a few bad actors in this tragicomedy. Worst of all, as far as we know now, it was an FBI agent — identified by the New York Times as Frederick W. Humphries II — who took it upon himself to transmit a raw report on the case to a member of Congress. That isn't whistle-blowing. It has nothing to do with the rule of law or the national security of the U.S. The singular significant fact of the affair thus far is the way in which it came to light. The agent, and the FBI as an institution, should be called to account.
The bureau has the awesome power to destroy anyone in the U.S. by searching their computers, rifling their records, reading their mail and stealing their secrets. It can do that under law, with a judge's warrant. Or it can ruin people for no real reason, as it did for decades under J. Edgar Hoover.
The CIA as an institution has reason to resent the conduct of the FBI in this case. It would be a disaster if that resentment revives the long-standing rivalry between the agencies. For more than 50 years, they were at each others' throats, constantly skirmishing and sniping. And the more they made war, the less safe Americans were.
Their failure to cooperate contributed mightily to the success of the Sept. 11 attacks, as the 9/11 commission concluded. The national security chief at the FBI, John O'Neill, and the head of the CIA's bin Laden desk, Michael Scheuer, refused to share crucial intelligence. They built walls between their agencies, mortared with mutual hatred. After O'Neill was killed inside the World Trade Center during the attack, Scheuer testified in public that his death was "the only good thing" that happened that day.
Hoover started the battle himself. He was a hater, and he truly despised the CIA from the day of its creation after World War II. He saw it as a rival for power; he cursed it as a haven for communist sympathizers; he cultivated secret informers within its walls. "It is a tragedy that the true phoniness of CIA isn't exposed," he wrote in royal blue ink on one of his innumerable broadsides against the agency.
Hoover's political warfare drove his Cold War counterpart, Allen Dulles, the CIA's chief from 1953 to 1961, to deep despair. "How in the world can I do business with the bureau?" Dulles shouted at his FBI liaison. "I try, and you keep striking back."
But the balance of power always lay with the bureau, and that power came from presidents. Franklin D. Roosevelt gave Hoover the secret authority to eavesdrop on Americans, to plant hidden microphones in their bedrooms and boardrooms, and to purloin secrets through burglary and break-ins. When the U.S. Supreme Court outlawed telephone wiretaps, Roosevelt told Hoover: To hell with the court. Harry Truman worried aloud that the bureau would become an "American Gestapo." John F. Kennedy knew Hoover had 20-year-old sex tapes of his tryst with a suspected Nazi agent; he shared his national security adviser's opinion that Hoover was "a goddamned sewer" collecting and disseminating dirt.
Presidents want the bureau to give them secret intelligence (and sometimes political scuttlebutt). It serves as a sword and a shield. But in the FBI's hands, the sword can cut both ways.
Unique among federal agencies, the bureau can break presidents. Richard Nixon fell because the FBI fearlessly investigated Watergate (and secretly leaked the facts to reporters). FBI agents made felony cases against Ronald Reagan's national security team in the Iran-contra imbroglio (Reagan protected himself by appointing the bureau's director to take over the CIA). The FBI literally drew blood from Bill Clinton; the DNA evidence led to his impeachment for lying about sex.
The bureau's current director, Robert S. Mueller III, deserves great credit for trying to make peace between the bureau and the agency. That hasn't been an easy task, but his endurance in office has been a blessing. The CIA, deposed from pre-eminence in the American intelligence establishment, discredited by bogus reporting on phantom weapons of mass destruction in Iraq, dishonored by brutal interrogations of suspected terrorists in secret prisons, rarely keeps its directors for long; five men have held the post in the past eight years. By contrast, Mueller — who took office, God help him, on Sept. 4, 2001 — has served with quiet distinction for more than 11 years in the J. Edgar Hoover Building.
In Hoover's day, instructors at the FBI Academy taught newly hired agents to revere Hoover by citing the words of Ralph Waldo Emerson: "An institution is the lengthened shadow of one man." Hoover ruled by fear. He invented the modern surveillance state. And we still live in his shadow.
Mueller cannot sandblast Hoover's name off the FBI headquarters. He can come out of the building and rule that the FBI agent in this case was out of bounds. Backhanding raw case files to Congress is outside the law. For an agent to decide that he alone knows what is best for the U.S. — a decision that destroyed the director of the CIA — is a dirty business. At the least, a confession of error made by Mueller in public — and by the agent, preferably under oath — might help prevent renewed hostilities between the nation's two best known intelligence services.
Mueller should make clear to the American people that the FBI will not and cannot conscience a return to an era of backstabbing and blackmail. That kind of blood sport was supposed to have died with Hoover, 40 long years ago.
Tim Weiner, a former reporter for the New York Times, is the author of "Enemies: A History of the FBI" and "Legacy of Ashes: The History of the CIA." He wrote this column for Bloomberg View. His email address is firstname.lastname@example.com.


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06 September 2007 15:30
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IBM Global Services Security Practice: Rising ProfileBy Mel Duvall | Posted 2002-09-16 Print
Dossier: In the wake of September 11, Big Blue has reorganized its safety and security practice to complement its business continuity and disaster recovery offerings.
Security products and services have always been a big part of IBM Global Services' business. But after Sept. 11, IBM created a safety and security practice within Global Services, assembling its safety and security offeringsalong with its substantial business continuity and disaster recovery servicesunder Rusine Mitchell-Sinclair, a 20-year information technology veteran. The practice includes 3,000 consultants and about 100 researchers at her disposal.
"One of the chief reasons you bring in an organization like IBM is because you know they have the experience," says David Zink, the organization's vice president and CIO, who gives the company high marks for its work.
ChartOne, a San Jose-based company that stores medical records for about 1,400 hospitals in the U.S., retained IBM to consult on a security and storage-farm project. IBM now manages and provides disaster recovery services for the company's huge data warehouse. Sharad Patel, the company's chief technical officer, has been satisfied overall with IBM's work and ongoing support.
However, he says there were some problems early on in the project when IBM had to integrate its equipment with the company's Sun server environment. "Our engineering teams had to work together to make the hardware and software layer work together. But they stepped up to the plate to resolve the problem," Patel says.
The Napa Valley Wine Warehouse, a facility that stores wine for 54 wineries in California, brought IBM in to design and implement a secure extranet for its customers. General Manager Karen Ames was very satisfied with the work, but it came at a cost. "They are pricier, there's no way around that. But security was a big concern for me and my wineries," she says.
IBM Global Services Security Practice
3039 Cornwallis Road, Research Triangle Park, NC 27709
(919) 543-0091
Ticker: IBM
Exchange: NYSE
Employees: 3,100 (3,000 consultants, and 100 researchers dedicated to security practice)
Rusine Mitchell-Sinclair
General Manager, Safety and Security Practice
Joined IBM in 1996, becoming a vice president with Global Services. Previously held executive positions with Blue Cross Blue Shield of New Jersey, and Rolm Corp.
Elizabeth Primrose-Smith
Vice President, Global Security Solutions
Appointed to position in 2001. Formerly in charge of IBM's sponsorship marketing efforts, including its huge involvement with the Olympic Games.
Harriet Pearson
Chief Privacy Officer
Responsible for guiding privacy policies across the company.
Security assessments, outsourcing, business continuity, disaster recovery. Partnered with Kroll for physical security.
Reference Checks
Napa Valley Wine Warehouse
Karen Ames
General Manager
Project: Used IBM to design and implement a secure extranet for the 54 wineries that use its facilities.
Union Bank of California
Robert Justus
Vice President, Systems and Contingency Planning
(415) 765-2969
Project: Brought IBM in to design and implement a secure online banking application.
Canadian Payments Association
Bob Hammond
General Manager
(613) 238-4173
Project: IBM designed and implemented a public key infrastructure project to allow for the secure exchange of transactions between banks and financial services companies. Also provided security assessment services.
Chart One
Sharad Patel
Chief Technical Officer
(408) 453-1600
Project: Brought IBM in to design and implement a secure storage farm to house medical records.
T. Rowe Price
Kirk Kness
Vice President, Application Architecture
(410) 345-2000
Project: Used IBM on a project to implement a secure access system so customers can gain access to multiple applications using one sign-on.
Blue Cross & Blue Shield of Rhode Island
David Zink
Vice President, CIO
(401) 459-1000
Project: Brought IBM in to consult on security to meet a 2001 deadline for making its information systems comply with the administrative standards of the 1996 Health Insurance Portability and Accountability Act.
Executives listed here have all been customers of IBM Global Services' security practice. Their willingness to talk has been confirmed by Baseline.
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Diamond light, brighter than the sun
It's the size of five football pitches and generates light 10 billion times brighter than the sun. As the Diamond Light Source celebrates its tenth anniversary this year, I visited one of the UK's biggest scientific investments to see how it works.
Imagine that the only thing limiting you is your imagination – that the physical means of achieving what you see in your mind's eye is right in front of you. That, according to Professor Mark Hodson, an environmental scientist at the University of Reading, is how it is for scientists like him using the Diamond Synchrotron in Oxfordshire. With its curving walls, lined with walkways, pipes and colourful, clunky-looking machines and gadgets it's a sight that wouldn't seem out of place in an early episode of Dr Who.
Outside, from a birds-eye view, Diamond looks like a massive ring doughnut or a spaceship half a kilometer in circumference (roughly the size of five football pitches). Its size and shape (in actual fact, it's a polygon of 24 straight sides) are dictated by its purpose. As the name suggests, Diamond is a source of intensely bright light that can be up to 10 billion times brighter than the sun. And it's not just visible light – Diamond is optimised to produce light with much shorter wavelengths in the form of X-rays and also generates infrared and ultraviolet light that is invisible to the naked human eye.
Researchers go to the synchrotron to use that brilliantly intense light much in the same way they use visible light in a microscope, or X-rays to reveal things we can't see. Microscopes work by passing visible (optical) light through an object. The refracted light passes through two lenses that focus it to create an image of the object's microscopic structures, then magnify the image so that we can see it. An X-ray machine passes X-rays through an object and captures the image created of its internal tissues on negative film. X-rays reveal the internal composition (tissues) of larger objects (like people), and microscopes the innards of tiny objects like cells that are only a few microns (0.001mm) in size, too small to be visible to the naked human eye.
The Diamond synchrotron is millions of times bigger than an X-ray machine or a microscope, yet the light it generates allows scientists to see the internal structures of things that are infinitely smaller, such as atoms. Atoms are measured in angstroms, one angstrom (1angst or 1Å) being 0.1 of a nanometre, which in turn is a billionth of a metre. To give you some context, a human hair is 100,000nm wide and an ant about five million nanometres long.
In trying to look inside an atom, scientists are trying to visualize something that is only 0.1 billionth of a metre big. To distinguish two objects (atoms) that are only 1Å apart, researchers need to pass a much more intense light through them. They need to use light with far shorter wavelengths than the visible light used in microscopes – either ultraviolet light or X-rays. It's the job of Diamond to produce that light and send it to the 'cabins', the laboratories surrounding the storage ring where the experiments are actually carried out.
How does Diamond create those intense, invisible forms of light? Like CERN in Switzerland, Diamond is a particle accelerator, using very similar technology. Both, as the term suggests, are designed to get particles zipping along at great speed. CERN sends neutrons and protons smashing into each other at high speeds approaching the speed of light to understand what particles – and the universe – are made of. Diamond, by contrast, accelerates electrons. It also doesn't smash them into each other and scientists don't actually do any experiments with the electrons themselves. Instead they use the high speed of the electrons to create intense light to use in their experiments.
The way the electrons are produced in the first place will be familiar to anyone who's ever owned a big fat old-fashioned TV. The cathode ray tube in the back of the TV heats up an alloy causing it to release electrons and fire them at the TV screen, which fluoresces, producing images. Diamond works on a similar principle, though on a much vaster scale. Rather than a screen, the electrons generated by heating an alloy in an electron gun are fired into a sequence of three accelerators. The first is the 30 metre long Linac, which increases the speed of electrons from almost no miles per hour to something approaching the speed of light. They then pass into the booster, where they gain energy, until they have enough to produce light of the kind and quantity needed to illuminate the atoms the scientists are looking at.
They then pass into the storage ring – the vast 560m2 tube that gives Diamond its shape and size. It is here that the electron bundles (beams) – which travel around the ring at roughly half a million times every second, generate synchrotron light and send it into the beamlines leading to the experimental stations (laboratories) surrounding the storage ring.
Magnets at the point of entry to the beamlines bend the speeding electrons around the corners of the polygonal storage ring and that causes them to release energy in the form of light (photons). This light spans the electromagnetic spectrum from infrared, through visible and ultra-violet light to X-rays.
Diamond is a 'third-generation' synchrotron, which broadly means that it uses more sophisticated magnets to create more intense light. At the beamline point of entry, 'insertion devices' cause the electron beam to wiggle backwards and forwards between the opposite magnetic poles. This 'constructive interference' produces very bright, very intense beams of X-rays – so intense that safety procedures are stringent. People cannot enter the lead lined hutches in which the experiments take place when the machine is operating, so experiments are controlled remotely from a separate control cabin.The power of these X-rays can help reveal atomic structure of proteins and inorganic elements like metals. Mirrors and crystals help focus the beams down to the wavelength required for each station, which then passes into the experimental hutch where it interacts with the substance the scientists want to 'see', the interaction revealing what it is made of at the atomic level.
Around 2000 research groups a year come to do experiments at Diamond that they could not do anywhere else. Research ranges from solving protein structures to designing drug targets. Scientists have used the synchrotron's light to look at the nutritional quality of wheat, assess the success of attempts to increase levels of zinc and iron in food, and work out which form of phosphate is best at locking up metal contaminants in soil. And iPod and iPad users may be interested to know that the technology on which they are based – giant magneto resistance – wouldn't exist without synchrotrons. With new beamlines coming online in the forthcoming third phase of Diamond's development, new possibilities for research abound to push the limits of scientists' imaginations.


text:
CGA coasts through Cougars
ROCHESTER — If there's a name for the defense Culver Girls Academy unleashed against New Prairie Friday, head coach Gary Christlieb isn't saying.
Whatever it was, it was effective.
The Lady Eagles, showing off a defense that resembled a diamond-and-one zone with elements of man-to-man and halfcourt trap, held the Cougars to a measly 10-of-44 shooting clip from the floor while creating 16 turnovers — including a 1-for-10 third-quarter effort with six turnovers in the same span — en route to a 43-24 Sectional 19 semifinal shellacking at Rochester.
"We can't divulge that; it's top secret," said Christlieb. "We've played a zone most of the season, and it works well with us. That's what we've tried to do. There are things that we've got to do a little bit better, a couple rotation issues, but overall that's been our mainstay on defense throughout the season. As the old saying goes 'You've got to dance with the partner you brought,' so that's what we're doing."
With 6-foot-3 sophomore standout Andrijana Cvitkovic controlling the lane, the Cougars had trouble penetrating the paint for easy buckets and couldn't work inside-out to the perimeter either, stumbling to a 4-of-13 conversion rate from 3-point land. Cvitkovic recorded five blocks while 6-3 senior sub Cassandra Hall swatted out another two, and CGA held New Prairie shooter Courtney Spencer to 3 of 13 from the field and nearly six points under her average with eight for the night.
"We thought we got a little bit too spread out in the first half trying to chase them so we kind of packed it in. They started to shoot from the outside, and I think our size really kind of took advantage at that point because then they really quit going inside at all," Christlieb said.
"That was the difference: We pushed their offense out of the middle, got them back out to the perimeter, and we were able to trap them in a couple spots, turn them over. When they did drive Cvitkovic did a nice job of controlling the lane and Hall did the same thing, and I think that probably was the key point that let us get into our run."
Cvitkovic sparked a 9-0 run spanning 4:54 of the first and second frames on a backdoor feed from point guard Kylee Shipley at the 48-second stop of the opening quarter, and the Eagles took a 19-10 lead into the intermission despite a relatively slow start. But it was their 10-2 third frame that put the game away as they kicked off the second half with 3-of-4 field shooting on their way to a 29-7 lead with one period to go.
Christlieb credited his team's start both to the emotional aftermath of CGA's nail-biting 49-48 sectional-opening win over three-time defending champion Plymouth Tuesday as well as the Cougars' patient offense.
"You come off of an emotional win Tuesday. To New Prairie's credit and to (New Prairie head coach) Dan's (Shead) credit, he went after us, tried to slow us down, and sometimes that gets kids lulled a little bit not only on the defensive end but on the offensive end as well," said the Eagles boss. "You think you've got to come out and make some plays. You get a little bit more rushed, and then you miss some of those layups that normally you're going to hit in the normal flow of the game. They clearly got the tempo into their favor, and then we were able to put the two runs on them that really put it into our favor. We got up and down the floor, hit some shots, got some layups, and that was where we moved it out to 20, and we felt fairly comfortable from that point on."
Culver converted 16 New Prairie turnovers into nine points and capitalized on a 41-28 rebounding advantage to push the pace with numerous transition layups off outlet passes.
Cvitkovic finished with a game-high nine points and 11 rebounds, and Shipley — who was recently named to Hoosier Basketball Magazines list of Top 100 Senior Girls — scored eight while distributing five assists with only two turnovers running the point for the Eagles.
"We want to get up and down the floor; we want to push the tempo, and we were able to do that," said Christlieb. "Early we got a little bit antsy, and then we settled down and let things come to us. It's tough for anybody in athletics but particularly for high school kids when you tell them 'Let the game come to you.' That is so important and relevant, but not always are you able to do that but those two (Shipley and Cvitkovic) did that."
New Prairie closes out a 7-14 campaign with Friday's loss, while CGA improves to 15-6 and moves on to Saturday's championship at 7:30 p.m. EST. Culver now faces host Rochester, which used a 21-16 fourth quarter to beat Mishawaka Marian 51-46 in the other Sectional 19 semifinal Friday as the Eagles vie for their first sectional title since the 1996-97 season and just the program's sixth overall.
Class 3A Sectional 19 Semifinal
at Rochester
Score by quarters
NEW PRAIRIE (24): Heather Macher 0 0-0 0, Courtney Spencer 3 0-0 8, Jessica Cinal 1 0-0 2, Samantha Emerick 1 0-0 3, Paige Thompson 0 0-0 0, Mary Gamble 2 0-2 4, Jayne Colanese 1 0-0 3, Katelyn Buford 0 0-0 0, Kelsey Prestin 0 0-0 0, Saraj Vanwaardenburg 0 0-0 0, Katie Singleton 1 0-2 2, Alexis Buford 1 0-0 2; Totals: 10 0-4 24.
CGA (43): Alexis Christlieb 0 0-0 0, Kenzie Ungar 3 0-0 6, Katie Gawor 0 1-2 1, Andrea Lin 0 0-0 0, Kylee Shipley 4 0-0 8, Annie Morshces 0 0-0 0, Brenna Newell 3 0-0 6, Victoria Christlieb 3 1-2 7, Cassandra Hall 1 0-0 2, Lindsay Haller 1 2-2 4, Andrijana Cvitkovic 3 3-5 9, Emily Gilland 0 0-0 0; Totals: 18 7-11 43.
3-point goals: New Prairie 4 (Spencer 2, Thompson, Colanese), CGA 0; Turnovers: New Prairie 16, CGA 9; Rebounds: New Prairie 28 (Spencer 5), CGA 41 (Cvitkovic 11); Assists: New Prairie 3 (Macher 2), CGA 9 (Shipley 5); Steals: New Prairie 8 (Macher 2, Gamble 2), CGA 11 (Shipley 5); Blocked shots: New Prairie 0, CGA 7 (Cvitkovic 5, Hall 2); Fouls (fouled out): New Prairie 8 (none), CGA 12 (none); Records: New Prairie 7-14 (final), CGA 15-6.


text: Ryan Reynolds is no stranger to hard-core fitness regimens, having even revealed that to get in superhero shape for next summer's Green Lantern, "You spend one day a week eating what you want and the other six days eating drywall and wood chips." His latest role in the white-knuckle thriller, Buried, in which he plays an American in Iraq who awakens finds himself 6-feet underground in a coffin, required no such diet and fitness routine. "Um…I'm in a coffin. Why would I have to get buff?" the actor deadpanned at the film's Cinema Society and 2(x)ist screening in N.Y.C. on Thursday night. When he emerged at the end of the 17-day shoot, spent entirely in a box the size of his 6'2′ frame, "I definitely did not look good," Reynolds told reporters. "I'd seen better days. I looked a lot like Don Knotts. If you know who that is, that explains it." –Suzanne Zuckerman


text:
United States Foreign Policy: Its Organization and Control; Report
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MY BOY LUKE 16.3 HANDS + COLORS OF FALL 17 HANDS - horse breeding - horse mating - to do this without hand breeding with these expensive horses MAKE SURE YOU...
Kindle - HnR Racing Thoroughbred Sprinter (Horse Racing Documentary) [04:58]
Producer: Ryan Nothhaft Twitter: @ryannothhaft Kindle's twitter: @HnRsKindle Gary Mandella's Twitter: @HRTVMandella This is a documentary featuring HnR Racing's multiple stakes winning thoroughbred sprinter, Kindle. This short film specifically highlights the beginning of Kindle's 2013 season, including the Monrovia and Santa Monica Stakes, both run at Santa Anita Park. Featured interviews include Hank Nothhaft, owner of HnR Racing, Gary Mandella, training of Kindle, and Edwin Maldonado, Kindle's current jockey. After a brief summary of Kindle's early career, featuring wins at Golden Gate Fields, Hollywood Park, and Fairplex Park, the film documents the decision to enter the Monrovia Stakes to compete against Mizdirection, winner of the 2012 Breeders Cup Sprint. The Monrovia Stakes is a Grade 2, $150000, six and one half furlongs race on the down hill turf course at Santa Anita. The Monrovia Stakes finishing Order: 1) Mizdirection 2) Kindle 3) Givine 4) Byrama 5) Broken Dreams Mizdirection is owned by Jungle Racing LLC and whose connections include Jim Rome, Bill Strauss and Alex Solis Jr, and trainer Mike Puype. Mike Smith is Mizdirection's current jockey. Despite finishing second in the Monrovia, Kindle appeared to be very healthy after the race. Taking advantage of her current race fitness, HnR nominated Kindle for the 2013 Santa Monica Stakes, a Grade 2, $250000, seven furlong race on the dirt. Santa Monica Stakes Results: 1) Teddy's Promise 2) Sugarinthemorning 3 ...
Choice Bro going for a daily stroll! [00:27]
John Sargent Racing. New Zealand-based thoroughbred trainers.
Peter Clarke on Black Caviar [02:51]
Renowned horseman Peter Clarke explains some of the work that goes into pre-training and rehabilitating thoroughbreds. Clarke also talks about his work with champion mare Black Caviar, a horse whose career he has been instrumental in.
Sunpenny Works on 07Feb13 [03:58]
Sunpenny is a 2 year-old filly by Good Reward out of the multiple stakes winning mare Cascade Corona by Pine Bluff. Become a partner an race at Emerald Downs with this quality thoroughbred and Z Thoroughbred Racing......


text:
We are now several months into the global food crisis, which is a much bigger deal than the subprime meltdown for most people in the world. Food prices have almost doubled in three years, threatening to push 100 million people into absolute poverty, undoing much of the development progress of the past few years.
The new hunger has triggered riots from Haiti to Egypt to Ethiopia, threatening political stability; it has conjured up a raft of protectionist policies, threatening globalization. And yet the response to this crisis from governments the world over has been lackadaisical or worse.
Start with the lunatic story of rice stockpiles in Japan. A new paper from the Center for Global Development describes how Japan's government imports rice in order to comply with its global trade commitments but withholds most of that rice from consumers lest they decide they prefer it to the local sort. Japanese traditionalists view the consumption of sticky, short-grained rice as a patriotic duty. So rather than letting Mrs. Watanabe corrupt her children's dietary habits, Japan stores much of its imported rice until it has become unfit for human consumption, whereupon it is sold to feed livestock.
From the perspective of Japan, stockpiling rice is a costly exercise in chauvinism, but Japan can afford that. From the world's perspective, the stockpiling is more serious. More than 3 billion people depend on rice as their daily staple, and half of them are very poor. Japan could save many of them from hunger if it released its stocks.
The scandal is not just Japanese, however. In order for Japan to sell its rice outside its borders, it needs permission from the countries that supplied it the United States, Thailand and Vietnam. A bit of U.S. leadership could deliver that permission easily, but the Bush administration is apparently worried about a backlash from American rice growers who see no downside in high prices, thank you very much. Not for the first time in Washington do the fat welfare queens of the farm lobby trample on the poorest people in the world.
Speaking of welfare queens, Congress passed a farm bill last week with thunderous bipartisan support. The bill includes reasonable subsidies for low-income Americans hit by high food prices, but it also sprays money at farmers who already earn more than the average taxpayer and contains shockingly little for the world's poor. Congress is considering a separate bill that would boost international food aid more substantially. But that measure has been met with shameful indifference by lawmakers and consequently has stalled.
Congress won't even act on a common-sense proposal from the Bush administration that food aid be reformed. If the United States bought some of the food that it donates from other countries, it could get aid to the needy faster and more cheaply. But that would upset American farmers and shipping interests, as a new Council on Foreign Relations paper emphasizes. The president's proposal has few takers on the Hill.
The Europeans, for their part, have their own way of entrenching hunger. Just as Japan is wedded to its rice culture, Europe is irrationally hostile to genetically modified food. Study after study has found no danger in seeds that have been manipulated to grow better, withstand insects or survive in arid soil. But the Europeans still feel squeamish, and their hang-up deters Africans from taking advantage of crop science lest their exports be barred from European markets. Again, a peccadillo that to Europeans is affordable starves people in the poor world.
Finally, poor countries themselves have made things worse. Panicked at the prospect of food riots, countries with crop surpluses have forbidden exports in an attempt to bottle up supply and keep prices down. More than 40 countries have imposed some kind of export restraint, with the result that countries suffering food deficits have seen prices hit the roof. This nationalized hoarding is frustrating international relief efforts. The World Food Program has sought to buy food from countries with surpluses, such as Pakistan, to ship to desperate neighbors such as Afghanistan. But Pakistan drags its feet about selling.
Part of the solution to the food crisis, as the Oxford economist Paul Collier has written, is to promote large-scale commercial agriculture in the poor world. But for that to happen, investors have to know that there will be a market for their exports. They won't risk their money if Congress is going to subsidize their American competitors. They won't risk their money if European prejudice is going to prevent them from using the best seeds that scientists offer. And they won't risk their money if the governments of developing countries short-circuit their profits with crazy export bans.
Sebastian Mallaby is a fellow for International Economics with the Council on Foreign Relations.


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If People Like You And Your Work They'll Pay; If They Like Your Work, But Don't Like You, They'll Infringe
from the cthulhu-saves-your-games dept
If people like you and like your work, they'll buy your games. If they like your work but don't like you, they'll pirate them.The first half of this statement is at the heart of the idea of connecting with your fans. Part of this ability to connect with your fans is to be more open and human with them. We have seen repeatedly how artists sell more of their work and scarcities associated with their work as they become more human to their fan base. As fans come to trust you and feel that they can approach you directly, even if that is through email, Twitter or Facebook, they will be far more likely to trust you enough to part with their money. This trust is one of the keys to Double Fine's success and a key to the success of any game developer. Similarly, it was seen in the way Louis CK treated his fans.
The second half of this statement is a lesson that many larger publishers, developers and others in the entertainment industry have forgotten. Because of that, they are suffering the fallout. DRM and other methods that show how little the developer or publisher trusts its fans breeds contempt within the fan community. While those consumers may still like the product, they don't like the way they are treated. This is one of the driving factors behind piracy. To top off the problem, these creators and gatekeepers set up walls between themselves and their fans. They do everything to avoid contact with fans outside carefully orchestrated scenarios. This turns fans off and decreases the amount of trust they have for these individuals and companies.
It's often said that people will just get stuff for free if they can. But, clearly, that's not true. We've seen so many cases of content creators being supported by their fans at tremendous levels (such as the two cases mentioned above) that there's clearly more to it. And it seems that a key element is whether or not fans actually like you. Some people suggest that the disconnect with piracy is that people value the work, but won't pay for it. But a more accurate realization may be that people value the work... but don't value the creator if the creator doesn't value them. When the two sides value each other, it seems people are more than willing to pay.


text:
I ask, because I don't want to waste a bunch of time compiling a crap load of packages that the updater wants me to emerge if I don't have to. Also, if that is the way to do it; what would be the easiest way to keep those packages updated so entropy doesn't install them again with python2.5 support? I assume I could just package mask them for entropy, but how could I use portage to check for updates on those particular packages?
Code: Select all
emerge -v =python-2.6.2
The reason I want to do this is that a program called "calibre" requires python 2.6 or greater. I have already submitted a package request for it. However, because it requires python2.6 I don't see it happening anytime soon as sabayon would need to include python 2.6 as well.
which brings another point up. why is 2.6 not included? I understand it is "unstable" as yet, However, it is a slotted install so we could keep 2.5 installed alongside it. What would be the issue with that?


text:
Danbury boys basketball edges Staples 70-68 in double OT
DANBURY -- Its postseason hopes swinging in the balance with every possession in overtime, the Danbury High boys basketball team did its best Monday to withstand Staples' offensive punch.
And when the ball landed back in the Hatters' hands late in the second overtime -- with the score knotted at 68 -- guard Danyjoel Harris did the rest.
Harris took an inbounds pass, dribbled nearly the length of the court and knocked down a jumper at the foul line right before the buzzer sounded, lifting the Hatters to a 70-68 win over Staples at home.
"They let us get the ball in and our option was to get the ball to (Harris), and isolate him," Danbury coach Casey Bock said. "It worked out where he got the ball and made a good shot."
Harris, who did not start the game, finished with 14 points for the Hatters (7-12, 5-12 FCIAC), who can clinch a state tournament berth with a win at Greenwich on Wednesday.
Forward Mike Kline led Danbury with 15 points, while Corey Brosz added 12.
Staples led once in the second overtime -- 64-63 on a layup by forward Ross Whelan -- before Danbury re-took the lead by a point on a bucket by Kline. The Hatters went ahead twice more, but Staples tied it both times.
Forward Nick Esposito's layup tied it for Staples 68-68 with under 10 seconds left in the second overtime.
"I'm really proud of our kids," Staples coach Colin Devine said. "They responded to every situation -- down two, up two. We just came up a little short at the end. That's all it really is."
Staples dropped to 11-8 (10-7 FCIAC) and likely needs to win its season finale -- Wednesday against Bassick -- to earn a berth in the eight-team FCIAC playoff field. The Wreckers entered the day in sole possession of seventh place, a game ahead of Wilton.
"These kids have responded all year," Devine said. "We lost four games in a row and then ran seven out of eight. There's no reason after one day of practice that we can't respond."
The Wreckers led twice by two points in the first overtime, but each time, Danbury answered right back.
The Hatters jumped ahead 57-55 and had an opportunity to push their lead to two possessions. But guard Corey Chaffee dribbled the ball off his foot with 48 seconds left, leaving Staples a chance to tie it.
On Staples' next possession, guard Peter Rankowitz did just that, drilling a jumper to make it 57-57.
Rankowitz finished the game with 20 points, while Staples guard James Frusciante led all scorers with 29 points.
"They're a solid team, and for us to pull this one out was nice," Bock said. "I give us some credit. We got stops when we needed to get stops, and (Harris) hit a big shot there at the end."
Danbury trailed 32-28 at halftime and by five points after three quarters, but got to within 50-40 in the final two minutes of regulation.
Staples pushed the lead back to three quarters with 49 seconds left when Frusciante made one of his two foul shots.
Kline, however, tied it up 51-51 with a 3-pointer from the top of the arc late.
"It was pretty nerve-wracking, but the team stood together. We kept playing hard and came out on top," said Chaffee, who finished with 11 points.
Staples connected on just 14 of its 26 free throws in the loss.
Whelan scored 11 points for the Wreckers.
203-255-4561 ext. 114; twitter.com/DougBonjour
Jake Melnick 0 0-1 0 James Frusciante 8 9-14 29 Joe Greenwald 0 0-0 0 David Katz 0 0-0 0 Nick Esposito 2 0-2 4 Darryle Wiggins 2 0-4 4 Ross Whelan 4 3-4 11 Peter Rankowitz 7 2-2 20. Totals 23 14-26 68
Mike Kline 5 3-8 15 Corey Chaffee 5 0-2 11 Danyjoel Harris 6 1-3 14 CJ White 0 0-0 0 Washaun Hendricks 0 0-0 0 Marquise Marrero 1 0-0 2 Donovan Trimandilis 4 0-0 9 Tysheen McCrea 0 0-0 0 Javonte Parker 0 0-0 0 Jalen McCallum 3 1-3 7 Dezshawn Daley 0 0-0 0 Corey Brosz 4 2-2 12 Will Orr 0 0-0 0. Totals 28 7-18 70
3-pointers: S -- Rankowitz 4, Frusciante 4; D -- Kline 2, Brosz 2, Harris, Chaffee, Trimandilis.
Fouled out: S -- Melnick, Wiggins; D -- McCallum.


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Babson By The Numbers
On a quarterly basis, President Schlesinger challenges members of the Babson community to prove their knowledge of recent accomplishments and happenings through a new initiative, Babson by the Numbers. Community members can make guesses, join the conversation via Twitter at #Babsonbythenumbers, or follow via Storify updates. On an ongoing basis, these key numbers related to Babson are compiled here for our ambassadors to keep on hand and top of mind for use in conversations about Babson.


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PeterK needed a new logo design and created a contest on 99designs.
A winner was selected from 89 designs submitted by 16 freelance designers.
TheGangGreen.com is a website run by NY Jets fans. We've been around since July 2000 and are currently in the process of redesigning the site. The current logo was created by a professional logo designer in 2004, but I feel like it's time for something new and fresh.
mostly males of different ages, although the vast majority is 15-35, located in the United States
Green (#055843 or #004231) and white have to be the dominating colors. Some gray (#e7e7e4 or #cdcdcd) can also be used. This has to be a professionally looking sports logo that will be used on the website, message board, and possibly t-shirts. I expect to receive AI or EPS files of the logo. The current logo is at http://www.theganggreen.com
Feel free to ask questions and thank you.
P.S. I see that some people are just submitting a nicely typed website's name (fancy fonts, gradients, etc.). If I wanted something like that, I'd do it myself. What I want is a real logotype, not just my site's name written using nice looking fonts.
Find out how a design contest works or learn more about our logo design services.


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Time: 11 a.m. today, KCNC, KREZ, KRSJ 100.5 FM.
Opening Line: Broncos by 3½.
Record vs. Spread: Denver 5-3; Carolina 4-4.
Series Record: Broncos lead 2-1.
AP Pro32 Ranking: Broncos No. 8; Panthers No. 25.
Last Meeting: Panthers beat the Broncos 30-10, Dec. 14., 2008,
Last Week: Broncos beat Bengals 31-23; Panthers beat Redskins 21-13.
Broncos Offense: Overall (3), rush (17), pass (4).
Broncos Defense: Overall (10), rush (12), pass (10).
Panthers Offense: Overall (20), rush (12), pass (17).
Panthers Defense: Overall (13), rush (20), pass (13)
Streaks, Stats & Notes
John Fox spent nine seasons (2002-10) as the Panthers coach and posted a 73-71 record.
QB Peyton Manning (419) needs two TD passes to surpass Dan Marino for second most in NFL history. Brett Favre is the NFL leader with 508.
Manning registered his 48th game-winning drive in the fourth quarter or OT last week, passing Marino (47) for most in the NFL since 1970.
Manning has three TD passes in five consecutive games.
RB Willis McGahee needs 14 yards rushing to reach 8,000 for his career.
WR DeMaryius Thomas has been a big beneficiary of Manning, posting career-bests in catches (45) and yards receiving (756).
WR Eric Decker seeks his sixth consecutive game with at least one TD reception. He has four TDs in last two games.
Since 2011, Joel Dreessen has 10 TD receptions, second-most among AFC TEs.
DE Elvis Dumervil has five sacks in his last five games.
LB Von Miller had a career-high three sacks last week vs. the Bengals and has 20½ sacks since joining the NFL in 2011.
KR Trindon Holliday had a 105-yard return last week, longest in Broncos history.
In his first 24 career NFL games, QB Cam Newton is the only NFL player with 5,000-plus yards passing, 25-plus TD passes, 1,000-plus yards rushing and 15 rushing TDs in his first two seasons.
Newton is 8-16 as a starting QB and 3-1 vs. AFC opponents.
RB DeAngelo Williams had a 56-yard TD run in his last game vs. Denver.
WR Steve Smith caught his first TD pass of the season last week. Smith has eight 100-yard receiving games vs. the AFC in career.
WR Brandon LaFell has a reception of 20 or more yards in six of seven games hes played. He missed last weeks game with a concussion but is expected to play.
DE Charles Johnson looks for his third consecutive game with at least two sacks. On the other side, DE Greg Hardy has 4½ sacks in his last two games. The Panthers are the only NFL team with two players (Johnson and Hardy) with at least 6½ sacks.
Associated Press


text:
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CLEMSON, S.C. (Jan. 7, 2010) - After having a month off from competition, the ETSU men's and women's track and field team returns to action when the Bucs compete at the 2010 Clemson Invitational this weekend inside the Clemson Indoor Track and Field Complex.
The two-day meet kicks off Friday evening at 5 p.m. with the men's and women's 60m hurdles (prelims), along with the women's high jump and shot put. Eighteen men's and women's combined titles will be contested on day one.
ETSU will send 30 of its athletes to South Carolina this weekend (19 men/11 women), as they look to build off their strong showing from the season opener at Appalachian State back on Dec. 5.
Four Buccaneer student-athletes took home first-place honors in Boone, as junior hurdler Mike James (Palm Bay, Fla.) set a NCAA Provisional Mark in the 55m hurdles, clocking a time of 7.35. Joining James with top honors on the men's side were junior Ben Ronoh (Sotik, Kenya) and senior Duronal Monal (Belle Glade, Fla.). Ronoh won the crown in the mile, as he finished six-hundredths of a second faster than his cousin Kenneth Rotich (Nairobi, Kenya) with a time of 4:22.21. Meanwhile, Monal was tearing it up in the short sprints by winning the 55m title (6.30).
On the women's side, junior Jasmine Ingram (Frederick, Md.) kicked off the season with a bang in the 800m. Ingram led the charge for the Lady Bucs in the event - finishing with a top time of 2:22.48. The Frederick, Md. native will compete in the 800m and the 4x400m relay on Saturday afternoon.
For complete results on the Clemson Invitational, visit www.ETSUBucs.com for a full recap of events following each day of competition.
For more information on Buccaneer track and field, visit www.ETSUBucs.com.


text: Hi I've come across a interesting situation with the amavisd policy settings, specifically regarding message size restrictions. The situation is this: I have set message size restrictions in my main config file using @message_size_limit_maps (for example: [email protected] => 3*1024*1024) In ISPC the [email protected] mailbox spam policy is set to 'Normal' which has it's message size restriction set to zero. Amavisd interprets this value as disable which overrides my main config file value. Manually setting the value to NULL in the spamfilter_policy table fixes the situation and amavisd adheres to the value set in the main config file. Is this behavior intended? It's problematic for me as I would like to enforce size limits that a user cannot override by setting or changing their policy. Chaning the default value of zero to NULL would fix this.


text: Round Three of Late-Winter Storms for the Midwest March 4, 2013 02:02 AM Tweet TAGS: Marketing, Overseas December 18, 2014 By Bloomberg Email March 4 (Bloomberg) -- A late winter storm that may bring heavy snow to Chicago tomorrow is expected to strike the East Coast later this week, potentially tying up air traffic and causing power outages. Odds are better than 70 percent that Chicago will get at least 6 inches (15 centimeters) of snow from the storm, according to the Hydrometeorological Prediction Center in College Park, Maryland. "For Chicago, it should get in there after midnight and won't start to taper off until late tomorrow evening," said Tom Kines, a meteorologist with AccuWeather Inc. in State College, Pennsylvania. "The evening commute tomorrow is still going to be a bear." The storm, the third to strike the Great Plains and Midwest in three weeks, will cross the northern Plains, passing some of the nation's hardest-hit drought areas, then curve below the Great Lakes. Winter storm advisories, warnings and watches stretch from Montana to Ohio and have also been posted in the Appalachian Mountains from North Carolina to Pennsylvania, the National Weather Service said. Winter storm and snow warning have also been posted in southern Saskatchewan and Manitoba, including Winnipeg, according to Environment Canada. After Chicago The challenge for forecasters is figuring out what the storm will do it as moves east across the Ohio Valley, Kines said. Where it goes then will determine how much snow falls on East Coast cities from Washington north to New York and possibly Boston. If the storm takes a more southerly track to the Atlantic, Washington and Baltimore may get the worst of the snow, he said. It might start raining in those cities late tomorrow and change over to snow on March 6. At least 5 inches of snow are possible across northern Virginia and into Maryland, including Washington and Baltimore, according to a weather service winter storm watch. There is a greater than 50 percent chance at least 4 inches of snow will fall in that area, according to the Hydrometeorological Prediction Center. If the storm moves farther north, Philadelphia and New York City may see significant snow, Kines said. If the storm were then to hug the U.S. East Coast, Boston and northern New England may be affected. Travel Disruptions Kines said the storm will certainly affect mid-week air travel along the East Coast. "For anybody traveling Wednesday and Thursday, there is no doubt there are going to be problems in the East," Kines said. As of 8:30 a.m. New York time, 117 flights were canceled around the U.S. with 77 of them into and out of Minneapolis-St. Paul International Airport. Light snow is falling there and the cities may receive more than a foot in the next 36 hours, according to the weather service. The storm, packing gusty wind and heavy, wet now, may also trigger power outages across the Mid-Atlantic states, including the Baltimore-Washington area, the day after tomorrow, according to Matt Rogers, president of the Commodity Weather Group LLC in Bethesda, Maryland. --Editors: Charlotte Porter, Bill Banker To contact the reporter on this story: Brian K. Sullivan in Boston at email@example.com For More Information Check your local weather forecast with AgWeb's Pinpoint Weather. Back to news


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Capone-N-Noreaga - My Attribute
The official music video for "My Attribute" by Capone-N-Noreaga off of their new album, The War Report 2, dropping tomorrow.
Please click the "Report" button below if the video on this page is not working properly.
Comments will only be displayed by verified emails. No Spamming or Racism.


text:
Your Medford Chiropractors
dts - spinal decompression
safe & effective chiropractic
Dr. O'Keefe was named
South Jersey TOP Physician 2016
"Eighty-six percent of ruptured intervertebral disc (RID) patients achieved
'good' (50-89% improvement) to 'excellent' (90-100% improvement) results
with decompression. Sciatica and back pain were relieved." "Of the facet
arthrosis patients, 75% obtained 'good' to 'excellent' results with decompression."
Source: C. Norman Shealy, MD, PhD, and Vera Borgmeyer, RN, MA.
Decompression, Reduction, and Stabilization of the Lumbar Spine: A Cost-Effective Treatment for Lumbosacral Pain. American Journal of Pain Management Vol. 7 No. 2
A new study, recently published in the medical journal Spine, found that patients who seek chiropractic care for back pain are far less likely to undergo lumbar surgery than those who consult a surgeon. The study found that approximately 43 percent of patients who saw a surgeon first when seeking treatment for back pain ended up having surgery, as opposed to 1.5 percent of patients who first saw a chiropractor. These findings support the long held position that many health care providers subscribe to that attempting to treat back pain should start with conservative approaches, such as chiropractic care. Read more...
Source: Spine
Wellness Care
People ask, "Why should I have my spine evaluated when it doesn't hurt?" That is a good question, and I will endeavor to give you a good answer.
Many spinal conditions develop over a period of time. Initially, spinal disc degeneration may cause no pain at all. However, as the condition advances, it can become a painful and lifestyle altering condition. A spinal evaluation can detect developing problems, and appropriate treatment can alter the course of the condition with much less treatment and no disability at all. If you wait for pain to occur, it will often take more time to correct the problem. You should not wait for a toothache to see the dentist. You also should not wait for back pain to see a chiropractor.
Spinal maintenance is based on each patient's need and unique condition. People who are more physically active with no arthritis will tend to need minimal maintenance care. People with degenerative arthritic conditions, with more sedentary lifestyles, may require more periodic attention. Remember, maintenance or wellness care is based on each patient's individual needs.
Wellness care also includes recommendations to diet, nutrition, exercise, proper rest, and improving your overall lifestyle to achieve optimum health.
Yours in better health,
Michael J. O'Keefe, D.C., DAAPM
O'Keefe Chiropractic Center, P.A.Thank you for visiting the O'Keefe Chiropractic Center, P.A. website. Within this website, you will find information regarding the conditions we treat and the types of treatments that we offer. This site also provides useful information as it relates to wellness and overall health.
We hope you enjoy the information within and share it with others. Again, thank you for visiting www.southjerseyspinaldecompression.com and remember to come back often.
Yours in health,
Michael J. O'Keefe, D.C., DAAPM
David L. Jones, D.C.
*These are individual results, results may vary.
|8:00 A.M. to 8:00 P.M.
|8:00 A.M. to 4:00 P.M.
|8:00 A.M. to 8:00 P.M.
|8:00 A.M. to 4:00 P.M.
|8:00 A.M. to 8:00 P.M.
Spinal Educator
Click the animation below to learn more.


text: Director Peter Segal was at WonderCon plugging his upcoming Get Smart film, but he also talked a bit about the Shazam/Captain Marvel movie he's slated to helm. While he didn't reveal anything new (they're talking to The Rock about playing Black Adam, etc), he did say that the tentative new title for the project is Billy Batson and the Legend of Shazam. Which sounds like the name of one of those .99 cent DVDs they sell at Target near the front door. You know, the junk you've never heard of? Shazam! is a perfect title, and it might finally eradicate the existence of the Shaquille O'Neal movie Kazaam from our minds. [Comic Book Movie]


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The U.S. Justice Department has announced that it will not be prosecuting Wall Street firm Goldman Sachs or its employees following an investigation into financial fraud. A Senate panel had been investigating allegations that Goldman marketed four sets of risky mortgage securities without informing their clients that the securities were risky.
The Senate panel, chaired by Senator Carl Levin (D-Mich.), asserts that Goldman Sachs bet against investors' positions and tricked investors about those positions in order to shift the risk.
According to the Justice Department, officials "have determined that, based on the law and evidence as they exist at this time, there is not a viable basis to bring a criminal prosecution with respect to Goldman Sachs or its employees in regard to the allegations set forth in the report" from the Senate subcommittee.
The statement continued, "The department and investigative agencies ultimately concluded that the burden of proof to bring a criminal case could not be met based on the law and facts as they exist at this time."
Despite the DOJ's assertions that there is not enough evidence to bring a criminal prosecution against Goldman Sachs, Goldman Sachs agreed to pay $550 million in civil fraud charges after the SEC determined that the company had in fact misled its investors. That agreement applied to one of the four deals that were being investigated by the Senate subcommittee. And Goldman employee Fabrice Tourre is still facing a civil complaint from the SEC.
The DOJ did add that the decision could change if new evidence were to emerge. "If any additional or new evidence emerges, today's assessment does not prevent the department from reviewing such evidence and making a different determination, if warranted," the statement said.
The investigation from the Senate panel revealed several emails from Goldman Sachs employees wherein they spoke of the complex mortgage securities sold to banks and investors as "junk" and "crap." Levin indicated that he believed the company's employees "misled the Congress" and that Goldman Sachs "gained at the expense of their clients and they used abusive practices to do it." He also questioned whether employees were being truthful in their testimony regarding whether the firm encouraged investors to purchase securities that employees knew would fail.
Goldman Sachs CEO Lloyd Blankfein asserted that the company was not guilty of betting against its clients.
The announcement from the DOJ was the second piece of good news that Goldman Sachs received that day. The Washington Post explains, "The Justice Department's decision capped a good day for Goldman as the Securities and Exchange Commission decided not to file charges against the firm over a $1.3 billion subprime mortgage portfolio."
But the Justice Department's decision could hurt the Obama administration, particularly during an election season in which the president is attempting to portray himself as an anti-corporatist.
Obama's relationship with Goldman Sachs has been a closely intertwined one, however. The following Goldman Sachs people have either worked for or are currently working for Obama's administration: William Dudley, president of the Federal Reserve of New York, is a managing director and partner of Goldman Sachs; Gary Gensler, chairman of Commodity Future's Commission, spent 18 years at Goldman Sachs; Mark Peterson, chief of staff to Treasury Secretary Timothy Geithner, is a former lobbyist for Goldman Sachs; Philip Murphy, nominated for ambassador to Germany, is a former Goldman executive; and Diana Farrell, Deputy Director to the National Economic Council, was formerly with Goldman Sachs. These are just a few of the many Goldman Sachs associates who can be found in the Obama administration.
Additionally, Goldman Sachs purchased 10 percent of the Chicago Climate Exchange in 2006 after President Obama had orchestrated a transfer of funds from the Joyce Foundation to the Chicago Climate Exchange when he served as an influential board member of the Joyce Foundation. Goldman Sachs had a vested interest in Obama's push for cap and trade when he became president.
In 2008, Goldman Sachs was one of Obama's top campaign donors, pouring over $1 million into his campaign coffers.
In 2012, however, Goldman Sachs has switched gears. Business Week reports:
Four years ago, employees of New York-based Goldman gave three-fourths of their campaign donations to Democratic candidates and committees, including presidential nominee Barack Obama. This time, they're showering 70 percent of their contributions on Republicans.
And Goldman Sachs is not the only one. Thirteen other companies are following suit.
Rogan Kersh, provost at Wake Forest University in North Carolina, noted, "A switch in party preference of this magnitude is virtually unheard of among major companies with an established presence in Washington."
Analysts believe that Goldman Sachs' sudden change of allegiance could be enough to compel the Obama administration to reconsider an investigation into the firm.
The Government Accountability Institute (GAI) released a report recently which determined that the failure of President Obama and Eric Holder to criminally charge Wall Street bankers is a result of collusion because political donations made to Obama's campaign.
The Daily Caller reports:
Despite Obama's and Holder's "heated rhetoric" against Wall Street (in 2009, Obama blamed the 2008 financial collapse on "reckless speculation of bankers" while Holder charged that "unscrupulous executives, Ponzi scheme operators and common criminals alike have targeted the pocketbooks and retirement accounts of middle class Americans"), they haven't "filed a single criminal charge against any top executive of an elite financial institution," GAI wrote in its report, exclusively obtained by The Daily Caller.
And as noted by the GAI, Obama's staff is not comprised only of Goldman Sachs' people. Much of the leadership at the Department of Justice comes from "white-collar defense firms where they represented the very financial institutions the DOJ is supposed to investigate," states the report. That includes Holder, Associate Attorney General Tom Perrelli, Associate Attorney General Tony West, Assistant Attorney General Lanny Breuer, Deputy Attorney General James Cole, and Deputy Associate Attorney General Karol Mason.
In fact, the report asserts that by selecting Holder as Attorney General over a "more fiery prosecutor," Obama sent "a subtle signal to the financial community" that they are ultimately safe from any real action from this administration against their financial misdeeds.
Obama showed similar indiscretion, according to the report, when he refused to appoint an independent counsel to investigate the MF Global scandal, although over 60 members of Congress demanded it.
The report explains,
GAI points out how [Tony] West — the DOJ's no. 3 official — worked as a white-collar defense attorney for Morrison and Foerster before he came to the DOJ. Morrison and Foerster is currently providing legal representation to MF Global. Holder and Breuer's old law firm — Covington & Burling — provided legal services to MF Global too, before MF Global sought bankruptcy protection.
Despite the rhetoric, observers have noted that President Obama is just as much a corporatist as he asserts his rival, Mitt Romney, to be in his political advertisements.
Photos: Goldman Sachs Headquarters in Manhattan (left) and Goldman Sachs Tower in Jersey City.


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Wine Getaway at AAA Four-Diamond Hotel Overlooking Niagara Falls
As many as eight million visitors a year come to Niagara Falls. The water is certainly a sight to behold, and you can see it from the Marriott Gateway on the Falls. But the falls' commanding presence often means that the Niagara region's many wineries get overlooked. Winemaking has been a pastime here for 200 years. You can sample the fruits of that labor at many family-owned vineyards near Marriott Gateway on the Falls. As part of this deal, you'll get VIP passes that give you access to four wineries in the surrounding Niagara region. You'll enjoy tastings and tours. When you come back, you can enjoy dinner at the onsite Milestones Grill + Bar. It's situated on the mezzanine level and has floor-to-ceiling windows overlooking the falls. Enjoy grilled mediterranean chicken ($18.99) and fire-grilled salmon ($22.99), and sip on signature cocktails such as the popular frozen bellinis topped with sangria.
The Marriott takes full advantage of its majestic views of Niagara Falls wherever possible. There are 32 stories of picture windows overlooking the falls. Falls-view rooms provide close-up peeks of the Canadian Horseshoe Falls and American Falls. City-view rooms overlook the city of Niagara Falls.
Niagara Falls, Ontario: Panoramic Views of the Falls near Vegas-Style Casinos and Water Parks
At Niagara Falls—considered by many to be one of the world's seven natural wonders—water thunders downward from a height of nearly 200 feet, crashing onto craggy boulders below. The falls straddle the border between Canada and the United States, with segments located in both New York and Ontario, but the Canadian side of the Niagara River is universally hailed as the finest vantage point to take in all three of Niagara Falls' photogenic brinks: American, Bridal Veil, and Horseshoe Falls.
Year-round, Journey Behind the Falls grants a glimpse behind the curtain of Horseshoe Falls—board an elevator that descends 150 feet into the bedrock. A 10-minute walk from the falls, you'll see the neon glow of the Clifton Hill neighborhood.


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text:
Fraser Speirs - Blog - Future Shock:
For years we've all held to the belief that computing had to be made simpler for the 'average person'. I find it difficult to come to any conclusion other than that we have totally failed in this effort.
Secretly, I suspect, we technologists quite liked the idea that Normals would be dependent on us for our technological shamanism. Those incantations that only we can perform to heal their computers, those oracular proclamations that we make over the future and the blessings we bestow on purchasing choices.
I'm often saddened by the infantilising effect of high technology on adults. From being in control of their world, they're thrust back to a childish, mediaeval world in which gremlins appear to torment them and disappear at will and against which magic, spells, and the local witch doctor are their only refuges.
With the iPhone OS as incarnated in the iPad, Apple proposes to do something about this, and I mean really do something about it instead of just talking about doing something about it, and the world is going mental.