text:
Is it possible to deform the metric $g$ of a closed Riemannian manifold $(M,g)$ satisfying $\mathrm{Ricci}(M,g) > 0$ and $\mathrm{sec}(M,g) \geq 0$ to a metric $g_1$ satisfying $\mathrm{sec}(M,g_1) > 0$?
I understand that this question is ludicrous, at best (for instance, an affirmative would prove that $S^n\times S^m$ always carries a metric of positive sectional curvature). I'm assuming that there is a counterexample, but I can't seem to figure it out. Most examples of manifolds with positive Ricci curvature that I know can't admit metric of non-negative sectional curvature for topological reasons, for instance the Sha--Yang construction of metrics with positive Ricci curvature on connected sums of $S^n \times S^m$.
I was wondering about this in view of the following two results: The first, due to Aubin and Ehrlich, asserts that a metric $g$ with $\mathrm{Ricci}(M,g) \geq 0$ everywhere and $\mathrm{Ricci}(M,g) > 0$ somewhere can be deformed into a metric $g_1$ with $\mathrm{Ricci}(M,g_1) > 0$ everywhere. The second, due to Gao--Yau, asserts that if $\mathrm{Ricci}(M,g) > 0$ everywhere, then $g$ can be deformed into a metric $g_1$ with $\mathrm{Ricci}(M,g) > 0$ everywhere and $\mathrm{sec}(M,g) > 0$ somewhere.
The Gao--Yau result is a local solution to the intial question.
As a related question: Suppose the Ricci curvature of $(M,g)$ is pinched. Does this change the answer to the question if the pinching constant is particulary small or would it seem that pinching plays no role in this? Is there any theory of pinched Ricci curvature?
T. Aubin, Metriques riemannienes et courbure. Diff. Geom., 4:383--424, 1970
P. Ehrlich, Metric deformations of curvature. Geom. Ded., 5:1--23, 1976
L. Gao, S.-T. Yau, The existence of negatively Ricci curved metrics on three manifolds. Invent. Math., 85:637--652, 1986

subset: commoncrawl


text:
With tons of tears running down my face I loaded up my tortoise shell kitty and took her to a vets office that I'd never been to. Seems kinda rotten, dying someplace you don't even know - but I guess no one gets to choose anyway.
I learned that they had a special room, just for pets that might be euthanized - and it had it's own exit - so you don't have to cart out your dead through the waiting room of healthy happy animals. I was escorted there without much to-do when I walked into the office sobbing - they seemed to know JUST who I was and led me right back.
The nurse came in and discussed some very preliminary blood work that would let them figure out if she had system failure vs. illness - and of course I agreed.
I didn't have any HOPE - but I agreed.
The took the blood out of her NECK - and I about threw up.
After about 30 minutes the vet came in with the test results.
None of her systems were failing - she was, obviously at 18 - an OLD CAT - but her systems were in better shape than they would've expected at her age. No what they found was a very very sick cat. Upper respiratory infection plus kidney/bladder infections had taken her perilously close to death.
With no other option, other than to just put her down, I agreed to IV fluids and antibiotics shots and surprise surprise, I brought home a meowing and pissed off kitty.
Due to her age, and the severity of her illness, it's still quite possible she will die. But if she gets better, the vet felt she would get BETTER and return to her quality of life she had before which was just fine.
So we'll wait. The vet says that if she isn't better in 3-4 days she might not get better and to be prepared for that. And so we are.
All I know is that today I made the worst decision of my life, to take the life of my friend - because I thought she was suffering. If I had been right, I know that it would've been the right thing to do for her. But I don't know how I would've ever lived with the overwhelming guilt of denying her life,and of watching the life leave her little furry body.
I got off this time. And I'd like to thank whomever for that.
I wasn't ready.
Monday, February 22, 2010
Kitty Came Home
1 comments:
- Melissa said...
I'm glad she came home and is feeling better. Putting down a furry friend can be a very heart wrenching decision. My mom held our cat, Cinder, in her lap, when it was his time. It didn't make it easier on us, but at least he was with "his human". Much Love!!
- Wed Feb 24, 06:07:00 PM


text:
Primary Care Specialist - Diabetes - Fife, Tayside and Grampian
Primary Care Specialist Opportunity with an independent, innovative, research and development driven company!
Our client is a family owned company with a focus on vision and leadership and a commitment to improve health and quality of life within the UK through continuing research and development of medical products. They have a reputation for providing effective products for the treatment of chronic obstructive pulmonary disease (COPD), heart attack, secondary stroke prevention and treatment, high blood pressure, thromboembolic disease, HIV/AIDS, Parkinson's disease, stroke, diabetes and Non-Small Cell Lung Cancer (NSCLC).
The Primary Care Specialist responsibilities will include:
* Selling within the relevant therapeutic area into primary care * Working with business teams to ensure that KPI's and at met and target customers are met within set timeframes, with all data being logged into CRM. * Manage and optimize the budget/resources allocated to projects in order to meet objectives and targets * Candidate will have a demonstrable knowledge of account management along with the ability to build and maintain long term relationships
The ideal candidate will have/be:
* Degree level or equivalent and ABPI qualified * Experience working within Diabetes ideally * Sound experience in the relevant therapeutic field along with awareness of brand strategies * Candidate will have experience within a sales role, ideally within the Pharmaceutical arena * Good understanding of NHS framework and policies * Due to the highly competitive nature of the product area applicants will need to be commercially astute and have strong self-motivation
Apply to this amazing opportunity now via the website or contact Kelly Beetham at the Manchester Office!
Star is a full service resourcing and outsourcing company which resources at all levels for pharmaceutical, medical devices and technology, clinical research and healthcare communications companies in the UK and Ireland on a headcount and outsourced basis. If you haven't heard from us within 7 working days of submitting your application, please assume that you haven't been successful on this occasion. We wish you the best of luck with your job search.
You may return to your current search results by clicking here.
This website uses cookies. Read our cookie policy for more information. By continuing to browse this site you are agreeing to our use of cookies.
This website uses cookies. Read our cookie policy for more information. By continuing to browse this site you are agreeing to our use of cookies.


text:
Sign In to access this Webcast
The Chinese economy is slowing more sharply than expected due to the weak external global backdrop and domestic constraints and imbalances. The outlook still
anticipates a soft landing for the Chinese economy, as Chinese officials enact monetary and fiscal policy stimulus to bolster the sagging economy. But risks are rising for a harder landing than currently anticipated. In addition to looking at how a both types of landings will affect the U.S. economy, this webcast examines the longer term outlook for the Chinese economy and the prospects for rebalancing.
Kathy Bostjancic
Kathy has extensive experience providing insightful global economic and financial market analysis and forecasts to institutional and retail investors and Fortune 500 business leaders and professionals. She has a deep understanding of U.S. monetary and fiscal policy and its impact on the economy a...Full Bio
William Adams
William (Bill) Adams is assistant vice president and senior international economist for The PNC Financial Services Group. His responsibilities include forecasting economic conditions and exchange rates, covering emerging Asia, the European Union, Canada and Latin America. Adams serves as the prin...Full Bio


text:
The virginal (or virginals) was a domestic keyboard instrument, the earliest member of the harpsichord family; and derived from the psaltery in that it was a (usually) oblong box with tuned strings stretched along it, which were plucked (as against struck, as in the dulcimer or modern piano) to produce the sound. It was of a size suitable for placing on a household table; however some were built with their own frames or legs. A keyboard along one of the longer sides (i.e. parallel to the strings - which defines this instrument from other members of the family) has keys attached to wooden "jacks" which in turn have leather plectras (called "quills") which pass along the strings like fingers over guitar strings.
Its earliest recorded mention is in the mid-15th century and its greatest popularity was during the two centuries from 1600. William Byrd wrote for it and it was enjoyed by Mozart. Its etymology is problematical. Historic belief that it was so-named because it was played by Elizabeth I (the "Virgin Queen") have been disproved by references to its name before her reign. That it was played by the daughters of the household, and that the earliest book of compositions for the instrument is the "Parthenia" ("Maidens' songs") supports the idea that it was so-named because of its popularity as an instrument for young ladies.
The virginal is important in musical history as it was the first to show the potential of the keyboard. After the "Parthenia", four other major books of virginal music, the manuscripts of which have survived and are published, give insight into the development into this form of "serious" music.
Reference: That thing on the right.


text:
Connect your Google Nexus™ 4 or 5 phone directly to your HDTV using this SlimPort™ to HDMI® Adapter from Monoprice!
SlimPort is a technology based on the VESA DisplayPort standard that uses the micro USB connector for audio/video output and charging input. It supports the full 1080p high definition resolution, as well as 3D graphics modes.
This adapter allows you to output your phone's audio/video using just the adapter and a separate HDMI cable (not included). In most cases, external power is not required, with the phone's internal power being sufficient for the video conversion. However, a micro USB input port included, which allows you to connect to a USB charging source, so you can charge your phone's battery while using the HDMI video output.
Google and Nexus are trademarks of Google Inc.
SlimPort is a trademark of Analogix Semiconductor, Inc., in the United States and other countries.
HDMI, the HDMI Logo, and High-Definition Multimedia Interface are trademarks or registered trademarks of HDMI Licensing LLC in the United States and other countries.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.


text:
Asked by Lisa, via e-mail
How do I put my 11-year-old daughter on a diet? She is 50 pounds overweight, though she looks only about 20 pounds over. She has a lot of muscle. She plays sports year-round. She is a picky, picky eater.
She has asked to go on a diet, but I don't think that an 11-year-old should, even though it's unhealthy to be so overweight. I have told her she will need to give up sweetened drinks, sweet snacks and white bread products. Any other ideas that will not be too drastic but will show results?
Diet and Fitness Expert
Dr. Melina Jampolis
Physician Nutrition Specialist
Hi Lisa.
With the significant focus recently on childhood obesity, which has been boosted further by Michelle Obama's Let's Move campaign, this is an important question. Your instinct is correct in that your daughter should not be put on a diet, but it is unhealthy to be so overweight. This puts her at risk for a lifelong struggle with weight and chronic diseases, including heart disease, diabetes, cancer, joint disease and gallbladder disease.
It sounds like your daughter is quite active since she plays sports year-round, but don't forget to try to limit her TV time to two hours a day or less and do not allow meals or snacks to be consumed while watching TV.
In addition to giving up sweetened drinks, snacks and white bread products, increasing the fiber in her diet can help, particularly with decreasing belly fat. Try whole grain white bread as a compromise if she doesn't like whole wheat bread. Switch to brown rice and whole grain pasta for dinner. If she eats cereal, make sure that it is a brand with less sugar and more fiber that she still enjoys.
It is important that she eats breakfast every day and consumes portion-controlled snacks at designated times. Limit her juice consumption to 8 to 12 ounces per day and encourage water and low fat milk (not flavored milk or water, which is loaded with sugar).
Finally, make sure that she eats plenty of vegetables every day. This might be challenging but try to engage her in finding vegetables that she likes and preparing them in a way that taste delicious (topped with low-fat sauces or freshly grated Parmesan cheese) or including them in tasty dishes such as casseroles, pasta salads, lasagna and omelettes.
I wrote recently about incorporating veggies into your diet. Here are a few more recommendations from the American Academy of Pediatrics has more ideas.
Finally, it is important to talk with your pediatrician to help you decide on the right approach and to check basic blood work to look for complications of obesity. If her BMI (body mass index) is in the 85-95 percentile, meaning that she weighs more than 85 to 95 percent of children her age and height, and she has no complications of obesity yet, you should focus more on weight maintenance rather than weight loss. If her BMI is greater than 85-95 percent, and she already has complications of obesity, her calories should be reduced somewhat to allow for slow weight loss (no more than ½ pound or so per week).
But I think it is important not to let your daughter get too caught up with the number on the scale. Focus on helping her make better choices every day and the scale should cooperate.
Previous question:
Do rotation diets help food, sugar addictions?« Back to Diet and Fitness
Next question:
Is 9 daily servings of veggies (not fruits) OK?
CNN Comment Policy: CNN encourages you to add a comment to this discussion. You may not post any unlawful, threatening, defamatory, obscene, pornographic or other material that would violate the law. All comments should be relevant to the topic and remain respectful of other authors and commenters. You are solely responsible for your own comments, the consequences of posting those comments, and the consequences of any reliance by you on the comments of others. By submitting your comment, you hereby give CNN the right, but not the obligation, to post, air, edit, exhibit, telecast, cablecast, webcast, re-use, publish, reproduce, use, license, print, distribute or otherwise use your comment(s) and accompanying personal identifying and other information you provide via all forms of media now known or hereafter devised, worldwide, in perpetuity. CNN Privacy Statement.
The information contained on this page does not and is not intended to convey medical advice. CNN is not responsible for any actions or inaction on your part based on the information that is presented here. Please consult a physician or medical professional for personal medical advice or treatment.


text:
Journal & Topics
Lyft, the San Francisco-based ride-sharing company that competes with regular taxi service, will soon have a stronger presence near the Allstate Arena in Rosemont.
Rosemont Village Board members last week approved a proposal to allow Lyft to park 30 of its cars behind the arena's administration building off of Lunt Avenue giving it close proximity for customers wanting rides.
The one-year deal for the preferred spots will cost Lyft $150,000.
Lyft is a transportation network company similar to Uber. Customers are invited to download the company's app in order to contact a driver in the area. The company was founded in 2012.


text:
Critical Race Studies Program: Think. Teach. Transform.
The mission of the Critical Race Studies program is to:
think new ideas
teach future leaders and scholars and
transform racial justice advocacy.
The only program of its kind in the United States, UCLA Law's Critical Race Studies (CRS) program is the premier institutional setting for the study of the intersection between race and the law. Anchored by renowned scholars whose research represents the cutting edge of critical race theory in legal scholarship and related disciplines, our CRS program has no parallel in American legal education.
The cornerstone of the program is an academic course of study, the CRS specialization, which attracts the top students committed to racial justice scholarship and legal practice. Established in 2000, the specialization quickly emerged as a training ground for a new generation of practitioners, scholars, and advocates.
The CRS program augments coursework with research colloquia, symposia, interdisciplinary collaborations and community partnerships in order to integrate theory and practice.
To hear about about upcoming events and symposia, join the CRS mailing list.
The CRS Specialization is appropriate for law students who seek advanced study and/or practice in race and the law, critical race theory, civil rights, public policy and other legal practice areas that are likely to involve working with racial minority clients and communities or working to combat racial inequality. This Specialization in CRS consistently attracts the top students committed to testing and advancing new ideas for racial and social justice. CRS research and courses deepen our understanding of race and provide tools and strategies to help dismantle racism across the globe. In particular, the CRS specialization trains students to analyze how the law and legal institutions erect racial hierarchies. Students are simultaneously trained how to use law and legal institutions to dismantle those same hierarchies, to further basic civil and human rights.
Combining intellectual rigor and a passion for social justice and racial equality
Although the faculty and the coursework are outstanding, it is our heartfelt sense of community that makes the program extraordinary. CRS faculty actively participate in the Program and regularly share their research in academic fora, enjoy informal conversations with students, and provide valuable career advice. CRS alumni regularly return to talk about their jobs, and how a CRS education has helped them in their real world projects. Some have even organized workshops for first-year students interested in CRS to strengthen legal writing skills. Finally, CRS students take ownership of the program and innovate constantly, for example, by producing a critical race theory reader to complement the first year curriculum and organizing independent study workshops. Students enrolled in the specialization are also at the heart of the broader law school's life. They have included editors-in-chief of journals such as the UCLA Law Review, presidents of the Student Bar Association, and chairs of the major student organizations.
More Information
Jasleen Kohli
Director, Critical Race Studies Program
2238 Law Building
(310) 206-8178
Latest CRS Newsletter
Donate to CRS
Latest News
[Save the Date] CRS Symposium


text:
Minor update with a few new cities added: Zombie-wasteland, Tao Hua Yuan and IDIA. Plus some small fixes.
When in doubt, refer to the Wiki.
All example projects will be updated.
The Iam Framework for developers is here:
Newcomers are probably best served by downloading the IamTemplate project first, which is completely self-contained and also includes the IamFramework.jar and the javadocs:
Instructions how to get started and more can be found at the wiki: http://ai.bluemars.com/wiki.
Bugs can be reported on this forum.
Lastly there's the Iam Library. It is not strictly required to download this file in order to develop Iams. But if you want to follow the step-by-step introduction that's on the Wiki you're going to need it for some of the sections:


text:
Jump to navigation
Browse Content
MLML Home
MLML/MBARI Library
Digital Commons of Moss Landing Marine Laboratories
Managing our Digital Assets
You are here
Aiello, Ivano W.
Geller, Jonathan
Search results
List (default)
(1 - 32 of 32)
The Effects of Environmental Enrichment and Problem-Solving on the Brain and Behavior of Octopus rubescens
Effects of non-native species on two life stages of the Olympia oyster, Ostrea lurida, in the Elkhorn Slough estuary
Defining the Doratopsis: Investigating the Endpoint of the Paralarval Stage in Chiroteuthis Calyx
Effects of substrate warming on sessile marine invertebrate communities in Monterey Bay, California
Decorating Behavior and Decorating Preference in the Masking Crab, Loxorhynchus crispatus
DNA metabarcoding of meiofaunal communities along the California coast and potential abiotic drivers of distribution
Quantifying the emanation and decay of environmental DNA from three marine molluscs
Ribotyping and analysis of surface water microbe communities in the Elkhorn Slough estuary
Effects of community attributes on recruitment success of invertebrates in Monterey harbor, CA
Metabolic network construction based on the genome of the marine diatom Thalassiosira pseudonana
FISH-Flow: Fluorescent in-situ hybridization and flow cytometry to identify photosymbionts in corals after induced bleaching
Advancing spatial-temporal continuity in coral reef ecosystem pattern detection
Phylodemography of the blue rockfish (Sebastes mystinus) from California to Washington
Nuclear intron phylogenies and evolution of clonality among northeastern pacific Anthopleura species
Oceanographic influences on larval recruitment of benthic invertebrates in Monterey Bay
Molecular, histological, and behavioral differences in largemouth bass (Micropterus salmoides) and topsmelt (Atherinops affinis)
Characterizing dispersal patterns of Marbled Murrelets (Brachyramphus marmoratus) with genetic population assignments
The introduction of the Western Atlantic clam Gemma gemma to California
Mitochondrial genome architecture in sponges, with descriptions of two new species from the abyssal Northeast Pacific
Effects of acidified seawater on asexual reproduction and statolith size in the Scyphozoan Chrysaora colorata
Genetic variation among geographically isolated populations of the commercially important sea cucumber, Isostichopus fuscus,
The biogeography and distribution of megafauna at three California seamounts
Global phylogeography of thresher sharks (Alopias spp.) inferred from mitochondrial DNA control region sequences
Differential recruitment of Postelsia palmaeformis across substrate types and potential facilitative effects of turfing algae
Reproductive biology and growth of Anthomastus ritteri (Octocorallia: Alycyonacea)
Larval dynamics of brachyuran crabs in a high lattitude fjord, southeast Alaska
Settlement patterns of the mussels Mytilus spp. in Moss Landing, California
Factors influencing the pedal laceration frequency of a subtropical anemone
Biology of the red abalone, Haliotis rufescens, in Northern California
Flow cytometric analysis of phytoplankton viability in Elkhorn Slough, California
Settlement and post-settlement processes limit Calliarthron on subtidal walls
Discovery, cloning, and analysis of novel fluorescent proteins from various color morphs of Corynactis californica


text:
Partner & Top Producer
Peninsula Office
360 Primrose Road
Burlingame, CA 94010
McGuire Real Estate takes part in event focused on the impact of Chinese consumers on real estate markets worldwide.
SAN FRANCISCO—August 4, 2014—An elite group of luxury real estate professionals attended the Luxury Portfolio Immersion Conference July 20-22 in Shanghai, China. Participants include Lauren Bensinger, Director or Business Development; Judy Karam, Broker Associate; Robert Callan Jr., McGuire Partner; and Winnie Fok, International Sales Specialist, of McGuire Real Estate, an affiliate of Luxury Portfolio International®, the luxury face of Leading Real Estate Companies of the World®, a global network of more than 500 premier real estate firms.
The inaugural event presented a unique opportunity for a select group of luxury real estate specialists who work with Chinese home buyers and sellers, with the opportunity to gain a deeper understanding of Chinese culture and traditions and specifically how they may impact decisions relating to real estate.
Speakers included a talented line-up of luxury and cultural experts, such as Rupert Hogewerf, chairman of the Hurun Report and founder of the China Rich List, who shared insights on what drives China's highest net worth individuals. The group was also joined by Andrew Taylor, Co-CEO of China's premier real estate website, Juwai.com, who explored the nuances of setting up a business in a vast and diverse country such as China.
In addition, attendees heard from numerous experts on cross-cultural communication and the unique nuances of Chinese culture during the packed three-day event.
"McGuire's commitment to working with international clients, especially from China, has been strengthened by the many relationships we made in Shanghai, during the Luxury Portfolio International Immersion conference. From our experiences and the information we learned about the Chinese consumer and their needs for property in the US for themselves and their families, McGuire has developed a complete property program to assist these clients in the San Francisco Bay Area. McGuire is proud to have participated in such an exceptional conference" said Bensinger.
"The Immersion Conference marks a milestone for Luxury Portfolio, as we brought together a very committed group of real estate professionals who are making significant investments – in time, money and professional development – to better serve this highly influential and growing market," said Stephanie Pfeffer-Anton, executive vice president of Luxury Portfolio. "Opportunities such as this are a significant component in our strategic outreach to Asian consumers, which also includes a deeply enhanced online and print presence in the region."
Affiliates of Luxury Portfolio market high-end homes to affluent consumers worldwide through the program's strategic marketing program, including the award-winning website LuxuryPortfolio.com, which markets over 25,000 luxury homes to over three million high-net-worth visitors annually and features a total inventory of available properties totaling over $44 billion with an average price over $2.6 million dollars.
For more information about McGuire Real Estate please visit mcguire.com.
As a local, luxury boutique that focuses on the San Francisco Bay Area's high-end niche markets, McGuire Real Estate is a privately held corporation that was founded in 1919. We are headquartered in San Francisco's Marina District with offices in Noe Valley and SOMA as well Mill Valley, Berkeley, Burlingame, and Sonoma. McGuire is the exclusive international associate of Savills PLC, headquartered in London, and is a broker member of Luxury Portfolio® International, and Leading Real Estate Companies of the World®, which connects our McGuire agents and clients to a world-wide marketplace.
Visit mcguire.com for more information or contact McGuire Client Care at 1.800.4RESULT and firstname.lastname@example.com.


text:
Hope builds for a drug that might shut down a variety of cancers
The most frequently mutated gene across all types of cancers is a gene called p53. Unfortunately it has been difficult to directly target this gene with drugs. Now a multi-institutional research team, led by Dr. Lewis Cantley and investigators at Weill Cornell Medical College, has identified a family of enzymes they say is crucial for the growth of cancers that have genetic aberrations in p53. Targeting these enzymes with novel agents might prevent the growth of p53 mutant cancers, thereby benefiting a broad spectrum of cancer patients, including those with breast, ovarian, lung, colorectal and brain tumors.
In the Nov. 7 issue of Cell, investigators pinpoint two cellular enzymes—Type 2 phosphatidylinositol-5-phosphate 4-kinases α and β (Type 2 PIP kinases)—as essential for cancer growth when cells have lost p53, the powerful tumor-suppressor gene long dubbed the "guardian of the genome." More than half of all cancers lose this gene, allowing these cancers to grow at will.
The researchers discovered that the Type 2 PIP kinases are not critical for the growth of normal cells but become essential for cell growth when p53 is lost due to mutations or deletions. The scientists showed, in animal and lab studies of human cancer cells, that targeting these molecules effectively shuts down the growth of p53 mutant cancers.
Although the studies were conducted in human breast cancer cells, the researchers believe Type 2 PIP kinase inhibitors could block the growth of cancers with a mutated or missing p53 gene.
"The fact that one can delete the Type 2 PIP kinases in normal human cells or in mice with essentially no effect on cell survival suggests that inhibitors of these enzymes should have little toxicity," says Dr. Cantley, the study's senior author and director of the Cancer Center at Weill Cornell Medical College and NewYork-Presbyterian Hospital.
Dr. Cantley is already leading an effort to develop drugs to shut down these kinases. "Well-designed Type 2 PIP kinase inhibitors may turn the tide on p53 mutant cancer," he says.
A Crucial Link
Dr. Cantley is known for his discovery of the PI 3-kinase oncogene, and pioneering work in teasing apart how the gene contributes to cancer. PI 3-kinases (PI3K) have been linked to a wide variety of cellular functions, including cell growth and proliferation, and most cancers activate PI3K by one or more mechanisms. Dr. Cantley's discovery led to promising avenues for the development of personalized cancer therapies.
Activity of PI3K is in some cases linked to Type 2 PIP kinases, so in this study, Dr. Cantley sought to understand the function of these enzymes. Because the researchers knew that a subset of breast cancers over-express these molecules, investigators looked at their role in HER2-positive breast cancers, which typically are more aggressive tumors.
The researchers, including those from Harvard Medical School, Beth Israel Deaconess Medical Center and other institutions, discovered that the enzymes are silent in cells that have healthy p53. One critical role of p53 is to "rescue" cells that are producing excess reactive oxygen species (ROS), which are byproducts of cells that are growing too rapidly. The oxidative stress produced by ROS can damage cell structures, so p53 attempts to reduce ROS in affected cells. "If, however, ROS levels exceed the capacity of p53s to rescue it, then p53 takes on a second function, which is to kill the cell," Dr. Cantley says.
"That is why cancers often disable p53. If p53 is mutated or gone, then the cell keeps on growing at a very high rate," he says. "And then ROS begins to damage genes, making the cancer even more aggressive."
The Type 2 PIP kinases are the backup rescue system to p53. But they only reduce ROS enough to keep the cells from dying. (Too much ROS will also kill a cell.)
What this means is that cancer cells become "absolutely dependent on these kinases to be able to grow," Dr. Cantley says.
Taking Advantage of "Synthetic Lethality"
But there is a big and important hitch in this scenario, he adds. If the Type 2 PIP kinases are inhibited, and if p53 is deactivated, the cancer cell essentially "goes to sleep," he says. "It just stops dividing and growing. This is called synthetic lethality: You can get by without one gene or another, but if you lose both of them nothing can grow."
Shutting down these enzymes, as the researchers did in their experiments, puts cancer cells to sleep but has no effect on healthy cells. "A normal cell doesn't need Type 2 PIP kinases at all, so inhibitors of these enzymes should not be toxic to humans," Dr. Cantley says.
Because it is not possible to replace p53 proteins or the gene in cells that have lost it (many attempts have been made), deactivating Type 2 PIP kinases is the next-best thing, he adds. "This would likely be a very powerful advance in the treatment of many cancers."


text: Formulators of waterborne and UV coatings can now consistently achieve good spreading and wetting - even at low addition levels - thanks to a new family of Dow Corning brand superwetting additives effective on difficult-to-wet substrates such as wood, plastics and metal. Dow Corning 67 Additive and new Dow Corning 500W Additive, Dow Corning 501W Additive and Dow Corning 502W Additive are 100 percent silicone polyether copolymers that are recoatable; have little or no influence on slip; are solvent-free, BTX-free and low VOC; and are effective at low addition levels. In addition, Dow Corning 500W Additive is stable even at high pH, and Dow Corning 67 Additive and Dow Corning 501W Additive are compliant with European legislation for indirect food contact (Swiss Ordinance RS 817.023.21 Annex 6, Part B).


text:
In 1980, about 30 percent of Americans received some form of government benefits. Today, as Nicholas Eberstadt of the American Enterprise Institute has pointed out, about 49 percent do.
In 1960, government transfers to individuals totaled $24 billion. By 2010, that total was 100 times as large. Even after adjusting for inflation, entitlement transfers to individuals have grown by more than 700 percent over the last 50 years. This spending surge, Eberstadt notes, has increased faster under Republican administrations than Democratic ones.
There are conclusions to be drawn from these facts. You could say the entitlement state is growing at an unsustainable rate and will bankrupt the country.
But these are not the sensible arguments that Mitt Romney made at a fundraiser weeks ago. Romney, who criticizes President Barack Obama for dividing the nation, divided the nation into two groups: the makers and the moochers.
This comment suggests a few things. First, it suggests that he really doesn't know much about the country he inhabits. Who are these "freeloaders?" Is it the Iraq war veteran who goes to the VA? Is it the student getting a loan to go to college? Is it the retiree on Social Security or Medicare?
It suggests that Romney doesn't know much about the culture of the United States. Yes, the entitlement state has expanded, but the United States remains one of the hardest-working nations on earth. Americans work longer hours than just about anyone else. Americans believe in work more than almost any other people. Ninety-two percent say that hard work is the key to success, according to a Pew Research Survey.
It reveals that Romney doesn't know much about the political culture. Americans have not become childlike worshippers of big government. On the contrary, trust in government has declined. The number of people who think government spending promotes social mobility has declined.
The people who receive the disproportionate share of government spending are not big-government lovers. They are Republicans. They are senior citizens. They are white men with high school degrees. Far from living in the thrall of liberalism, the people who receive these benefits are more hostile to government than the average American.
Romney's comments also reveal that he has lost any sense of the social compact. In 1987, during Ronald Reagan's second term, 62 percent of Republicans believed that the government has a responsibility to help those who can't help themselves. Now, according to the Pew Research Center, only 40 percent of Republicans believe that.
The Republican Party, and apparently Mitt Romney, too, has shifted over toward a much more hyperindividualistic and atomistic social view — from the Reaganesque language of common citizenship to the libertarian language of makers and takers.
The final thing the comment suggests is that Romney knows nothing about ambition and motivation. The formula he sketches is this: People who are forced to make it on their own have drive. People who receive benefits have dependency.
But, of course, no middle-class parent acts as if this is true. Middle-class parents don't deprive their children of benefits so they can learn to struggle on their own. They shower benefits on their children to give them more opportunities — so they can play travel sports, go on foreign trips and develop more skills.
People are motivated when they feel competent. They are motivated when they have more opportunities. Ambition is fired by possibility, not by deprivation, as a tour through the world's poorest regions makes clear.
Sure, there are some government programs that cultivate patterns of dependency in some people. I'd put federal disability payments and unemployment insurance in this category. But, as a description of America today, Romney's comment is a country-club fantasy. It's what self-satisfied millionaires say to each other, and it reinforces every negative view people have about him.
Personally, I think he's a kind, decent man who says stupid things because he is pretending to be something he is not — some sort of cartoonish government-hater. But it scarcely matters. He's running a depressingly inept presidential campaign. Mr. Romney, your entitlement reform ideas are essential, but when will the incompetence stop?


text:
- Written by Admin
- Comments::DISQUS_COMMENTS
- font size decrease font size increase font size
Who can and can't start a business in France?
Now that you're here in Paris, perhaps you've been inspired to become an entrepreneur. That's wonderful! However, there are quite a few things to consider before you can begin the process. Make sure you do your research on regulations and requirements for your business and be prepared for lots of paperwork. Also, if you're not from a country in the European Economic Area (EEA), there are things you have to do before you can even pursue that wonderful new venture of yours.
Please note: This information is provided for informational purposes only. Please consult a professional for advice on starting your business. French-Property.com inspired much of the information contained in this article.
Also, due to the technical nature of this information, a lot of time and effort was expended to make it as easy to read as possible. Please let us know if there is anything we missed or needs changing!
Let's get started.
Oh, wait a second!
Do you have a Business and want to target customers within the expatriates' community in Paris (or its suburbs) without giving away large profit margins or investing in complicated mobile technologies? Expats Paris is a viable alternative to some of the sites you'd find out there. As one of the largest networks of Expats in Paris, we have a whole range of marketing/solutions & services to help you reach plugged-in local consumers. Get in touch Now!
Here we go!
To establish a business in France, EEA nationals don't need a residence permit. But non-EEA nationals must have a residence permit—visa de long séjour—which will include the nature of business activity in which you'll partake. You will need to go to your local OFII office to complete the paperwork for residency. Or, you may have to start with the French consulate in your home country, depending on your status and residency requirements.
You probably know this, but within the first three months of living in France (if you plan to stay longer than that), a resident must have a visa stamp. Now, if you already have a visa, but want to start a business, it will need to be updated to the kind of visa that allows you to open a business in France. Check out the OFII website for more information on visas. Also, once you do have your visa, you need to make sure you have your carte vitale (social security card for health insurance access), as that is required of all French residents, whether permanent or not if you plan to stay in the country for over three months. You can get it at your local CPAM office (which oversees French healthcare) and these locations can be found through the Ameli website.
Download our Free French Visa Guide Now.
Once you have the required visa, it's time to register your business. You will need to go to the Centre de Formalités des Entreprises (CFE). This organization informs all the bodies that need to know about your new business and will forward your application to the Greffe (French commercial court), which will check your criminal record. The entire process costs up to $250 euros. You will be given a receipt (Récépissé de Dépôt de Création d'Entreprise - RDCE) as proof that you've completed the process. Don't lose it.
Bring your passport, birth and marriage certificates, utility bills (to prove residency), banking information and proof of your qualifications, as necessary. According to French-Property.com, if you're married, your spouse is required to sign a declaration that s/he has been made aware of any debts being incurred against assets jointly held for this business.
Within two weeks, confirmation of your registration will be sent to you. It will be a document called an extrait K for the sole trader (entrepreneur/self-employed) or an extrait Kbis for companies. Consider this your official business identity card.
Your business will have a registration number with fourteen digits, known as the SIRET. The first nine digits—the SIRENE—refer to your registration number on the national business register. The remaining five digits identify your business geographically. This is your NIC (Numéro Interne de Classement).
You will also receive a separate five-figure code to identify your business activity. This is the APE (Activité Principale Exercée), formerly known as the NAF (Nomenclature des Activités Françaises).
To register the domain name of an internet site you will develop, use AFNIC, the French domain name registration agency. There are many other domain name registrars out there. Expats Paris, for example, was registered via OVH; a reseller and one of the largest web hosting providers worldwide. For a patent or something similar, use INPI, the French patents agency.
Image courtesy cfe.fr
In France, your business will likely fall into one of the categories below. If you have more than one business, chose the one that will be your principal activity when registering your company, and everything else will fall under it for tax purposes.
Five classifications:
Trade (Artisan) - this includes mechanics, plumbers, hair stylists and food processing activities, for example.
Professional (Profession Libérale) - also known as "freelance" fall into four categories: legal, medical, technical, artistic/teaching. Occupations such as writers, teachers, lawyers, dance instructors, interpreters, accountants, artists would fall into this area.
Commercial and Industrial - restaurants, shops, hotels fall into this category, including renting furnished apartments.
Commercial Agent (L'agent commercial) - anyone who represents another in the negotiation of the sale or purchase of goods or services, falls here.
Agriculture - farming and any supporting activity.
Infographic courtesy of Lefigaro
Check out this Guide to the French Income Tax Return.
How your business is structured will be the basis of taxes you pay, for the most part. If you are a sole trader (Enterprise Individuelle (EI)), you will be taxed under the personal income tax system Impôts sur le Revenu. As a limited company in sole proprietorship (EURL) you can choose to be taxed under the personal income tax system or through the system of company taxation Impôts sur les Societiés. A private limited company in joint ownership (SARL) will be taxed mainly under company tax, with one or two exceptions.
The Contribution Economique Territoriale (CET) is a tax used to help fund local services and the Chambres de Commerce/Metiers.
The CET has two parts:
● The Cotisation Foncière des Entreprises (CFE), using the value of the property occupied by the business.
● The Cotisation sur la Valeur Ajoutée des Entreprises (CVAE), based on the 'value added' each year by the business—your profits—and is used to calculate liability to VAT.
Still, according to French-Property.com, the minimum rates for 2016, based on turnover and subject to council resolution, are:
● Between €212 and €505 where the turnover of the business is less than €10,000.
● Between €212 and €1,009 where the turnover of the business is between €10,000 and €32,600.
● Between €212 and €2,119 where the turnover of the business is between €32,600 and €100,000.
● Between €212 and €3,532 where the turnover of the business is between €100,000 and €250,000.
● Between €212 and €5,045 where the turnover of the business is between €250,000 and €500,000.
● Between €212 and €6,559 where the turnover of the business is greater than €500,000.
The reference year used for determining the turnover figure is two years prior to the year of tax levied. Thus, for rates payable in 2016, the reference year is 2014. Exemptions depend on location, the discretion of council, and so forth.
You can elect to do your own accounting, or hire a professional accountant, depending on how complex your business is. There is also the option to work with the Centre de Gestion Agréé (CGA), which are local accounting centers. The fee is around €250 depending on where you live to become affiliated with them. They give business and accounting advice and can give you some relief on your taxation liability.
Don't forget to open a business banking account. Depending on how long you've been in business and the type of professional activity you're engaged in, you may get a reduction in fees for a time.
Also, check out 7 Things You Need To Know About The French Salary Slip.
Social Security
If you're self-employed, your social security contribution will be for health care, family allowances, pension and so forth. You won't pay for unemployment insurance. Once your business is registered, you will be contacted by various agencies regarding your contributions, and how it all works.
The Régime Sociale des Travailleurs Indépendants (RSI) provides insurance coverage for, among other things, health, maternity, and pensions to the self-employed.
If your business falls into one of the professions libérales categories, you will get your coverage from the RSI, but you will also pay into another pension fund administered by the Caisse Nationale d'Assurance Vieillesse des Professions Libérales (CIPAV). The fund to which you contribute will depend on your business purpose. Artistic professions will contribute to La Maison Des Artistes, and authors, the AGESSA.
The Union de Recouvrement des Cotisations de Sécurité Sociale et d'Allocations Familiales (URSSAF) is the main social security collections agency. Contributions to this organization are for family benefits, a training levy, and the social charges CSG/CRDS.
There are two main types of business taxes: regime réel and micro-entrepreneur.
Regime Réel
Under this tax status, you pay tax and social security on your actual net profits. What you pay also depends on whether you're doing so under personal or company taxation, as mentioned above.
2015 rates:
Table: Social Security Rates (TNS)
Charge Rate
Family Benefits 5.25%
Health6. 50%
Sickness Benefit 0.7%
Invalidity/Death 1.60%
Pensions (Main + Complementary) 25%
Training Levy 0.25%
Total (say) 48%
Most social security contributions are deductible business costs with the regime réel.
What's The Real Cost of Living in Paris? Check out what the figures were early this year (January to March 2016)!
Under this status, once you've created your business, you can choose to make your social security contributions monthly or quarterly, and it's based on your turnover for the previous accounting period. You have a thirty-day grace period for payment at the end of each cycle (first payment is made after the first three months of business). If you've had no turnover, then you won't be charged.
As for taxes, it depends on whether you use the régime de base (you'll pay income tax as part of your annual tax filing), or micro-fiscal (you will pay each accounting period, together with your social insurance payments), the latter being the default.
There is so much more to consider when starting a business in France. Make sure you thoroughly investigate the regulations and requirements of your chosen enterprise—are there classes you have to take, for example—so you'll be prepared for any eventuality. It might be expensive, but having an accountant to assist you in the process could be very helpful and save you time and headaches, especially if you're new to the country.
Bonne chance in your new venture!
Thanks for reading! Please leave a comment below and tell us about your experience starting a business in France. Was it easy or complicated? Thoughts on the process? Tell us more!
Sign Up for the Expats Paris Awesome Membership and get free and unlimited access to our eGuides to everything Business, Visa, Employment, International & Bilingual Schools in France and more. Do it here.
Do you want to receive some awesome articles about the joys, challenges, and lessons learned from expatriation adventures in Paris every week?
Don't worry, you can unsubscribe at anytime.
Related items
Latest from Admin
- Five ways getting an MBA will launch your international career
- Your French Language Survival Guide: 9 Tips On How To make It In A Parisian French-Speaking Sphere.
- An expat's guide to accessing public and private healthcare in France
- Loving an Alien: How does it feel to fall for a "foreigner"? PART 2
- Your Definitive Legal Guide To Hiring Staff In France


text:
|KASPAR, KERRIE - Washington State University
|PARK, JEAN - Iams Company
|Brown, Charles - Chuck
|MASSIMINO, STEFAN - Washington State University
|CHEW, BOON - Washington State University
Submitted to: International Journal of Food Science and Technology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/15/2012
Publication Date: 3/15/2012
Citation: Kaspar, K.L., Park, J.S., Brown, C.R., Massimino, S., Chew, B.P. 2012. Processing of pigmented flesh potatoes (Solanum tuberosum L.) on nutrient retention. International Journal of Food Science and Technology. 47:346-382.
Interpretive Summary: Specialty foods may have benefits for human health. Potato is a good source of vitamin C and potassium. However, some potatoes have high levels of other phytonutrients. Purple fleshed potato may have extremely high levels of anthocyanins and other phenolic acids. Yellow-fleshed potatoes have high levels of certain kind of carotenoids. The principal carotenoids found in potato are lutein and zeaxanthin. Both of these compounds are major constituents of the human retina and must be obtained from the diet. This study reports on the stability of red and yellow pigments, colorless compounds called phenolic acids and the ability of the extract of tubers to serve as antioxidants when processed into dried products by three different methods. The three methods were drum drying (DD), freeze drying (FD) and Refractance Window (RW). None of the methods reduced phenolic acids in the red and purple fleshed potatoes while FD and RW reduced them in the yellow flesh potato. Oddly, DD increased them in the white flesh potato. In the red and purple fleshed potatoes all forms of processing reduced the anthocyanin content considerably. In the yellow fleshed potato, all processing reduced the carotenoid content. Antioxidant capacity was reduced by all processing methods by a half to two-thirds. There are many options for producing dried products from potato that would reduce the costs associated with transport and storage. These studies indicate that several methods reduce but do not destroy the phytonutrient capacity of potato. Processing into a dried product that can be re-constituted for consumption is a viable option.
Technical Abstract: Antioxidant retention in white-, yellow-, red-, and purple-flesh potato cultivars after drum drying (DD), freeze drying (FD) and Refractance Window™ drying (RW) was compared. Dried potatoes were analyzed for total antioxidant activity, phenolics, anthocyanins and carotenoids. Total phenolics were high in all potato cultivars. Processing generally did not influence phenolics, except that DD increased (P <0.001) total phenolics in WP. The FD and RW decreased (P <0.001) phenolics in YP. The RP and PP cultivars had the highest anthocyanin concentration. Total anthocyanins in RP and PP decreased (P <0.001) with all drying methods. Total carotenoids were high in YP only, but decreased (P <0.01) after drying processes. Total antioxidant activity decreased (P <0.001) in YP, RP and PP after drying processes, but increased (P <0.001) in WP. Results indicate that drying processes generally decrease antioxidants in the finished product, with FD and RW retaining the highest concentration of antioxidants


text:
About this paper
Only a few months ago, the conversation about sharing clinical trial data was largely an argument of concerns and speculations against the idea. Spurred in part by growing momentum from government entities, the mood among life sciences companies has shifted to one of positive intention. It's just a matter of determining how to go about it. This article summarizes discussion on the topic with industry leaders at the second installment of the Clinical Trial Data Transparency Forum, sponsored by SAS, in February 2014.
About SAS
SAS is the leader in analytics. Through innovative software and services, SAS empowers and inspires customers around the world to transform data into intelligence. SAS gives you THE POWER TO KNOW®.
Have a SAS profile? To complete this form automatically Sign In
Welcome, . Edit Profile Log Out


text:
Beautiful Actress Kate Winslet, 36, went for a morning stroll with her two kids Mia, 11, and son Joe, 7 , and her new boyfriend in New York City today (November 3). Mia's father is Kate's ex-husband Jim Threapleton and Joe's father is Kate's ex-husband American Beauty director Sam Mendes.
Jen's airport sweetheart!
Actress, singer and mommy Jennifer Hudson and son David were spotted the Narita International Airport in Narita, Japan today
Jared Padalecki and Genevieve Cortese Expecting A Boy
Supernatural's Jared Padalecki and wife Genevieve Cortese are expecting a boy in March.
"I originally had the intuition that it would be a girl — shows what I know!" Padalecki, 29, tells Tonic.com.
"I grew up in a family where the oldest sibling was a boy and I appreciated the extra guidance and protection."
But while the couple are thrilled to be expecting a son, Padalecki admits a preference for baby's gender was never a priority.
Michelle Williams' Daughter Would Love For Her "To Grow Out The Cropped Hair"
The beautiful actress and mommy Michelle Williams is British Elle's cover girl for the December issue. Michelle is promoting My Week With Marilyn, talks about her pixie-styled haircut.She confesses that one of the reasons she has kept her short locks is because of 6-year-old Matilda's late father, Heath Ledger. She points out that "What Matilda would love is for her mom to grow out the cropped hair, though that's unlikely to happen any time soon. I cut it for the one straight man who has ever liked short hair and I wear it in memorial of somebody who really loved it." She adds, "I've really grown into it - I feel like myself with short hair. And it's been a really long time since I had long hair, five years. Of course, the only people who like it are gay men and my girlfriends. Straight men across the board are not into this hair!"
Mario's special visitors!
Actor and host of Extra, Mario Lopez got some special visitors yesterday (November 1)! His girlfriend Courtney Mazza and their adorable daughter Gia on the Extra set while filming at The Grove in Los Angeles, California yesterday
Neil Patrick Harris' family Halloween fun!
Actor and daddy Neil Patrick Harris went to twitter yesterday to share and adorable picture of him and his partner David Burtka as Peter and their twins Gideon and Harper as Smee and Tinkerbell. What a great idea!
Jess's post-baby wedding plans!
People.com reported that mom to be Jessica Simpson and fiancee Eric Johnson wedding has been postponed due to her pregnancy. "They're both still really committed to getting married, and were both really into making decisions about what kind of wedding they wanted," says a friend of Jessica and her fiance Eric Johnson. "It's just going to be at a later date now [because] they really want to enjoy this time in their lives."
Ali Later's little teddy bear!
Beautiful mommy and actress Ali Later was headed to a "Mommy & Me" class with her son Theodore aka. Teddy, 10 months, in Brentwood, California today (November 2).


text:
Product FAQs
Sunbeam® Steam and Press 2-in-1 Handheld Steamer
How long does it take for my iron to heat up?
Irons take approximately two minutes to heat up.
What causes brown spots or rust spots to come out of my iron?
If tap water is being used, a high mineral/iron content in the water may be causing the spotting. Also, if vinegar has been used to clean the iron, it may have caused rust/deterioration of the sole plate.
What is the warranty of the Sunbeam® Steam and Press 2-in-1 Handheld Steamer?
1 year limited warranty; see instruction manual for further details.
What should I do before using my iron for the first time?
- When turned on for the first time, your new iron may give off a slight odor for up to ten minutes. This is due to the initial heating of the materials used. It is safe, not detrimental to the performance of the product, and will not recur.
- Prior to first use, clean steam vents using the Shot of Steam® feature. After cleaning vents, run iron over an all-cotton cloth to remove any residue.
- When not ironing, always have steam dial turned to DRY.
- Test the Iron + Steamer on a rag or scrap piece of fabric to make sure there is no staining from initial use.
What should I use to clean the sole plate of my iron?
After the iron has been unplugged and completely cooled, wipe the soleplate with a clean, damp cloth. Do not use abrasive cleaners, scouring pads or vinegar.
Where can I purchase this iron locally?
The Sunbeam® Steam and Press 2-in-1 Handheld Steamer is available on our website or at any participating retail outlet. They are widely distributed through mass merchants and department stores.
Why is my iron leaving white residue on the sole plate or expelling white flakes?
The iron will leave white residue or expel white flakes if there are calcium deposits or starch buildup on the iron. The iron should be cleaned if this occurs.
Why is the light blinking on my iron?
This means that the iron is in Auto-off Mode, which happens when the iron has been motionless for 30 seconds. If the iron is moved while the light is still blinking, it will stop blinking and heat back to the desired temperature within two minutes.
Why is water in my brand new iron?
All of our irons are tested during production, so some of the water we used may remain in the tank. This is perfectly normal.


text:
United Nations Secretary-General Ban Ki-moon said today that South Sudan's President and his main political rival – whose respective forces are locked in an increasingly brutal conflict in the country – have said they plan to "sit down together" later this week for talks on ending nearly five months of fighting.
"I think this is absolutely necessary at this time. Since this crisis [began with] political issues…it is only natural that President Salva Kiir and Dr. [Riek] Machar sit down together to address [it] through dialogue, in a peaceful way," said Mr. Ban at press conference in the South Sudanese capital, Juba, wrapping up his one-day visit.
The Secretary-General said he will continue to emphasize to the two leaders that "even though they may have some different political views, there is nothing which they cannot overcome. They are same people, same country – this is their country."
The UN chief arrived in the world's youngest nation amid a conflict which began in mid-December 2013 as a political dispute between President Kiir and his former deputy president, Mr. Machar, who had been forced from office earlier that year.
The in-fighting has since erupted into full-fledged conflict believed to have left thousands dead and which has forced tens of thousands to seek refuge at UN bases around the country. The crisis has also been marked by numerous grave human rights violations. Mid-April also saw an upsurge in sectarian violence, with mass killings in Bentiu and Bor.
The Secretary-General said that when he visited the country three years ago for its independence ceremony, South Sudan had been full of joy, excitement and hope for the better future. "Yet today, I am standing here with a…heavy, heavy heart," he said, noting that he was frustrated and saddened by what he had seen on this current trip.
"I visited displaced persons who are now being accommodated in the UNMISS [UN Mission in South Sudan] compound. The United Nations will continue to help them so that they will be able to return to their homes as soon as possible," he said.
With all this in mind, Mr. Ban said he is "strongly supporting" the expressed intent President Kiir and Mr. Machar to attend peace talks, set to resume Friday, 9 May, in the Ethiopian capital, Addis Ababa. He had met with President Kiir in the capital and had spoken by phone with Mr. Machar.
While the UN and the international community are committed to providing humanitarian assistance, "we hope that peace will be regained as soon as possible," continued the UN chief.
"At the same time, I am urging the leaders and all those commanders of military units to fully protect the civilian population and also respect human rights and human dignity. Those who [commit] crimes against …international humanitarian law (and) human rights laws, they will have to be brought to justice," he declared.
The Secretary-General added that President Kiir had assured him that the United Nations – including the leadership of the UN Mission – have his full support.
Saying that he is proud of the courage shown by UNMISS, Mr. Ban added that by opening its gates around the country, the Mission had saved tens of thousands of lives.
While in the country, the Secretary-General visited the Tomping civilian protection site, which is currently home to some 21,000 South Sudanese civilians. He was able to see the hardship faced by the families living in the camp and pledged to them the UN's support.


text:
Manage Security and Privacy risk for your enterprise-wide data
Ensure Office 365 and SharePoint are enabling business success
Centrally manage and enforce policies for digital and physical records
Migrate, govern, and optimize Teams to drive real business value
Remote work is under control, and it's business as usual.
Migrate, backup, and manage your Small Business clients with ease.
Unlimited backup for Office 365 Groups, Teams, Sites and more!
Modernize your agency's case management and citizen incident reporting
Automate provisioning, management, and lifecycle for Groups, Sites, and Teams
A one-stop-shop for all your Microsoft 365 workspaces
Discover and visualize your Office 365 sites and content usage
Manage, move and secure your Office 365 content. Extend your IT workforce.
Manage physical and electronic records in Office 365
Find, prioritize, fix, and enforce Microsoft 365 security controls
Fast, flexible and intelligent data backup with on-demand restore for SharePoint
Automate privacy and security programs across your enterprise's content.
Enable users to self-provision workspaces, apply management and lifecycle policies automatically
Streamline and automate administrative tasks related to your collaboration environment
Easily inventory, plan, schedule and migrate from SharePoint to Office 365 or from tenant to tenant
Share and save content to SharePoint and Office 365 from desktop, Outlook, and Office apps
Provide internal and external users with secure, remote access to SharePoint
Define, manage, and enforce lifeycle policies for electronic content alongside physical records
Improve performance while reducing storage costs
Ensure the success of your enterprise content management or collaboration initiative
We offer 24/7 global support standard with all of our products
Our end-to-end service gets your data where it needs to be faster and with less risk
We can implement and configure our products for you to accelerate time to value
We can ensure your journey to Microsoft Teams is smooth and hassle-free
The best resources in one, easy-to-access place
Best practices from our network of renown industry thought leaders
What our customers are saying about their experiences
Upcoming webinars and other exciting industry events
What's new and now with AvePoint's award-winning products and services
24/7 global support comes standard with all of our products
Handy how-to guides on products and useful tools
Access user guides, release notes, account information and more! Account required.
Learn more about our history, core values and industry leadership
Learn about our commitment to Microsoft and our 20+ year partnership
Join our talented team
Read what the media has to say about AvePoint, and what we have to say to them
Our trophy case of industry awards for our innovative products and services
Our solutions are mentioned in numerous analyst reports
We want to hear from you! Contact information for our offices across the world


text:
Abstract and Keywords
Across the last 25 years, digital projects on the visual culture of Latin America have begun to shape, ever more fundamentally, both research and teaching environments. To be sure, books and journal essays remain the dominant mode of publishing (and significantly so), but digital projects—made possible in part because of increasingly accessible databases and less expensive editing platforms—are becoming widely recognized as key elements in the visual and intellectual landscape. The visual culture of Spanish America (also known as colonial visual culture or viceregal visual culture) extends across three centuries, dating from roughly 1520 to 1820. Yet its history, which embraces both the physical traces of everyday life and ephemeral experiences, is arguably the least familiar of Latin America's artistic and material legacies, especially outside Latin American Studies. Nonetheless, the period has inspired a suite of projects that, considered together, highlight the current potentials (and limits) of digital work, provide useful models for future research, and open onto debates relevant across the digital humanities (as they are currently called).
If this is the basic landscape, then what are the important issues when it comes to the intersections of digital technologies and colonial visual culture? This question is considered here along three avenues. First, what can be achieved with existing software, particularly imaging software, and the inherent epistemological assumptions imbedded in software commonly used? This topic receives the most attention because future research depends so heavily upon our perceptions and understandings of present technological capabilities. The second theme considered is accessibility. Given that institution-driven projects, most often online ventures sponsored by a museum or a library, have opened certain collections to an online public, what are the implications of the accessibility they offer, and how might such databases shape the parameters of research—both in the data they provide and in the kinds of questions their technologies make it possible to pose and answer? Finally, consideration is given to the possibilities and potentials for collaboration that the online environment offers in the study of visual culture of Latin America.
To set a framework for discussion, this article begins with a broad view, "The Object(s) of Visual Culture," and then turns to examples of scholar-driven projects currently online. Typically, these are generated by scholars working at universities and dependent upon both internal and external funding. The sections "Seeing Images, Knowing Landscapes" and "Epistemological Assumptions" not only describe examples, but also explore the modes of interpretation that digital environments enable and the habits of viewing that are produced as a result. Because scholar-driven projects do not exist in isolation, the article turns to institution-driven projects, represented primarily by digitized museum collections and archives, which have become central components of the research environment. Many projects in this vein are well-described elsewhere—our focus therefore rests on the effects on the larger research landscape, in a section called "Accessibility, Canonicity, Finance." Lastly, issues related to collaboration are dealt with, in order to both address ideas that are being explored through digital work in other fields, but which have not yet surfaced with much force in the field of colonial visual culture, and to ask why.
Keywords: Colonial Latin America, visual culture, digital humanities, viceregal period, art, architecture, lienzos, maps, manuscripts
Access to the complete content on Oxford Research Encyclopedia of Latin American History requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.
Please subscribe or login to access full text content.
If you have purchased a print title that contains an access token, please see the token for information about how to register your code.
For questions on access or troubleshooting, please check our FAQs, and if you can''t find the answer there, please contact us.


text:
Over the weekend, my local newspaper—The Santa Fe New Mexican—ran a story called "Drug companies pay thousands to local doctors." It seems that the investigative journalism coop named ProPublica has compiled a national database using public documents and disclosures of drug companies about monies paid to doctors, nurses and pharmacists. Apparently, about 40% of drug companies currently disclose this information, which shows they paid a total of $761.3 million to health practitioners since 2009, and a new federal law will take effect next year compelling all drug companies to do so.
While the "Dollars for Docs" database is accessible on the Internet, the New Mexican pointed out that 11 Santa Fe healthcare providers are on the ProPublica database, receiving some $2.2 million. The paper went on to list the four local doctors receiving the highest amounts (going back to 2009), ranging from $33,694 to $153, 032. The payments were for various services from research to speaking for professional education at venues large and small (Hobbs and Roswell, N.M., for example), including medical schools.
While the doctors who were quoted in the article said they enjoyed being involved in continuing education, and one of them pointed out that he would have made more money by staying in the office and seeing patients, the article included only one statement about the ethical nature of these payments: "What has become apparent over the years is that there are certain incentives by the pharmaceutical companies that are strong enough that physicians cannot mange those conflicts well, so it becomes problematic in their being able to render an unbiased prescription, for example," said Margaret McLean of the Markkula Center for Applied Ethics at Santa Clara University.
Yes, most of us can probably agree this is yet another example of some people and the media rendering a simplified (possibly predetermined) judgment about a more complex situation. And yes, at least to my mind, singling out a few of the doctors in the paper for public condemnation was unfair. But make no mistake, these kinds of stories are also effective. As New Mexico state senator Dede Feldman put it: "I think the pharmaceutical companies, knowing this is bad PR, have curbed some of the more excessive lunches and stuff."
Also make no mistake that if someone can create a database like this for doctors, they can also create databases for other professions, such as, oh, I don't know, maybe financial advisors. A similar database might disclose the compensation sources of various financial professionals: if they are W-2 employees of a bank or brokerage firm, who paid their 1099 income, who paid their commissions, who paid their trails, who paid for their due diligence trips, etc. How do you think this will play to a media that thinks buying lunch for a doctor to talk to a group of med students will compromise their professional judgment?
I know we're not there yet. But we will be: it's just a matter of time. Our current financial services industry is largely based on the public's confusion about the loyalties of various financial advisors and their inherent financial conflicts of interest. But sooner or later, they'll get the message: the media and the Internet will see to that.
The question is whether the duties and the conflicts will be sorted out in a rational, orderly, business-like manner. Or will the industry leave its restructuring to special interest groups with their own agendas, little understanding of the real issues involved or a stake in the eventual outcome?


text:
An avatar is really no more than a graphical representation, generally human, which is associated with a user for identification purposes. Avatars can be either photographs or art drawings, and certain technologies enable their use in three dimensions.
Until now, 3D avatars were mainly used as fun objects for diversion and entertainment purposes of the end user. However, the Media Unit at Tecnalia has developed a "Personalised 3D avatars" technology, the aim of which is to facilitate the building of low-cost 3D avatars.
This 3D avatar is used as a responsible interface to give advice to users, motivating them and guiding them while interacting with the computer. This new technology enables the provision of a novel solution in the use of these avatars in fields such as plastic surgery and Alzheimer's disease, and with which, based on high-quality 3D laser scanners and 2D photographs, Personalised 3D avatars are achieved.
In the case of plastic surgery, and using MODELVIR (Virtual Modelling) within the field of plastic and repair surgery, the surgeon is provided with an easy-to-use tool which enables graphically representing the current state of the patient, as well as a novel, three-dimensional representation of his or her external aspect after the operation. In this way the patient has a better idea of what the plastic surgeon can achieve, without creating illusions or raising false hopes that could give rise to subsequent disappointment.
Then there is ALZHERAPY, a technical project linked to the fight against Alzheimer's disease and that aims to provide rapid diagnosis for this pathology. Thus, the rate of advance of the disease slows on carrying out cognitive exercises. It has the added possibility of undertaking the daily monitoring and evaluation of the patient in a personalised manner, using an avatar that represents a person with a close likeness to him or her, and without having to leave the house. It even provides the possibility of enabling the patient to leave home without accompaniment (thus leading a normal pace of life) with total security, thanks to a device capable of detecting his or her position at any time.
Source: Elhuyar Fundazioa


text:
Page View
Alvares, Manuel, 1526-1583, et al. / Ethiopia Minor and a geographical account of the Province of Sierra Leone : (c. 1615)
Chapter 23: Superstition and the aspects of this false devotion, pp. 1-5
Page 3
This material may by protected by copyright law (e.g., Title 17, US Code).| For information on re-use see: http://digital.library.wisc.edu/1711.dl/Copyright


text: img_4279 Post author By Nick Post date October 6, 2020 No Comments on img_4279 By Nick I'm a father, husband, son. I love reading, drawing, writing, being active, having a beer or a glass of wine with my wife, and am curious about everything. View Archive → Comments welcome! Cancel reply


text:
Thursday, May 10, 2007
Subscribe to: Post Comments (Atom)
Posted by TreyPeezy.com at 12:01 AM
DISCLAIMER: All music link postings are for Promotiona Use Only! It is advised to delete files after 24 hours. This site is not responsible for anything as it only provides links.
SUPPORT: Even though it may be free, if you're feeling what's on here, GO COP IT! This site is here as a caution/preview.
REQUEST & DEAD LINKS: Any broken links? Want something that's doesn't work and need it re-upped? want to hear something/request something? Feel free to post a comment and I will try my best!


text:
A decade ago, Yamaha embarked on ambitious project to create software that could sing. The Vocaloid actually sort of worked and has even spawned some real music. But now, for some inexplicable reason, Yamaha jammed the technology into an actual physical instrument. Watching someone play the Vocaloid Keyboard will make your brain hurt.
The Vocaloid keyboard is actually two keyboards that, when combined, make the "singing synthesiser" come to life. But for now, it's only programmed for Japanese vocals. Your left hand triggers the syllables and your right hand controls pitch. As you can see from the video above, this thing is really hard to play, and it's hard to imagine a good reason to use it for live performances. [DigInfo via Geeky Gadgets]


text:
Wednesday, December 22, 2010
And don't let them drink out of the toilet, either.
13 comments:
No way! So, I should stop letting my 2 Y/O play in those LOCKED boxes at my MD's office?
Another save by Ibee and his faithful reader's.
Thanks "webhill," I must not be paying attention to my surrounding-I can never find "great stuff" like this.
WV: FORAN the last name of my 6th grade science teacher who we made beleive she was deaf (only during one class period a day). I swear she beleived it. My aunt was a teacher in the building and she mentioned it to a bunch of teachers and she was involced (my aunt) in the conversation. Crazy stuff. I was sad to hear she passed away a few years later from a brain bleed. Went out to dinner with her husband, had a headache, took two Tylenol and passed less than 30 minutes later. Sad!
- December 22, 2010 at 7:30 AM
- Community RN said...
Oh wow!! that falls under the category of too funny!!!!!!
- December 22, 2010 at 8:48 AM
There is a buzz killer everywhere you go these days.
- December 22, 2010 at 9:13 AM
Unfortunately, it is a problem. Mothers insist on bringing their kids into the ultrasound room with them. Then, as we are busy scanning mother, kid is busy getting into cupboards, pushing buttons on my machine, opening drawers, playing in biohazard garbage. Oh, look, little Tommy just loves machines..... I can't make my room kid-proof. Please make your kid room-proof!!
- December 22, 2010 at 9:52 AM
I'd love to hear the story behind that sign. Were the kids throwing urine samples around like bombs?
Playing patty-cake with the stool samples, then finger painting the wall?
My internist has a sign, "Your child breaks it, you'll pay for a replacement." He has had at least 3 oto/opthlamo scopes broken because parental units let them run amok in the exam room.
What parent thinks an ototscope is a suitable toy for a 2 year old?
- December 22, 2010 at 10:29 AM
Must be 18 or over.
- December 22, 2010 at 10:39 AM
- pharmacy chick said...
True Story:
Pharmacy chick's mom was a nurse. I've written about her. She came home with interesting things. One thing we had around the house and used a lot was a cooler like this that had been un-used. Blazened across the front of it was FROZEN HUMAN TISSUE.. we used it for picnics...(I wonder why nobody liked our pot lucks)
- December 22, 2010 at 11:03 AM
My son had a PICC line and, therefore, we had one of those red hazardous waste containers in our house. He loved the thing - always wanted to play with it. We ended up asking the nurse who came by to take blood samples and change everything to get us a clean one so he could play with it. He still has it. Makes a great Halloween decoration.
- December 22, 2010 at 12:23 PM
sad that parents have to be told things like that but I've seen it in the hospital I used to work at.Parents visiting Grandpa,kid in a stroller pulling stuff out of the red bio-hazard waste bin.One got mad because I yelled when I saw a little on chewing on some used ventilator tubing.gross
- December 22, 2010 at 1:31 PM
- Kat's Kats said...
Ya know, the really reallysay thing is that they have to put these signs up. Geez Louise!! As well as ones for adults for Pete's sake!! My kids were not only taught safety, they were taught the appropriate names for body parts (and I switched pediatricians until I found one that used them as well. (Imagine a two year old that gets confused because his ped doesn't use the term bowel movement or penis.)
reliked - anything you liked so much the first time...
- December 22, 2010 at 2:02 PM
- The Mother said...
We don't let ours play with the xray machine, either.
- December 24, 2010 at 9:22 AM
I wish to use this for a show poster for my punk band's next show. Please say yes.
- January 4, 2011 at 1:06 AM
- Grumpy, M.D. said...
Allie- Fine with me.
- January 4, 2011 at 7:21 AM


text:
A BUSHFIRE in Western Australia that had been threatening lives and homes is now control.
Authorities say that residents are no longer in danger in Kingia Road in the eastern part of Wundowie in the Shire of Northam, about 90km northeast of Perth.
The blaze was first reported at 2.30pm on December 23 but the Department of Fire and Emergency Services (DFES) said the flames reignited on Monday and jumped containment lines. It is now burning within containment lines.
"There is no threat to lives or homes but there is a lot of smoke in the area,'' a DFES spokesman said.
"Although there is no immediate danger you need to be aware and keep up to date in case the situation changes.''
The fire is believed to have been deliberately lit.
Residents can visit www.dfes.wa.gov.au or call 1300 657 209 for more information.


text:
I know a few Perl programmers read this blog and on the off chance that they read this and don't see it elsewhere ...
It's that time again! If you have an idea for doing some work for the Perl community and you think it's worthy of a grant, please send your grant entry to firstname.lastname@example.com. Grant applications must be in by the last day of July and we will be awarding the grants at the beginning of September.
First, please read about how to submit a grant. Read that carefully as grants are often rejected if they don't meet the criteria. For example, if you want to submit improvements to a well-known project but there's no evidence that you have at least tried to work with the maintainers of that project, the grant will likely not be approved. You can also read through our rules of operation for a better idea of thee grant process.
To get an idea of what sorts of grants are generally accepted, you can read through past grants for 2001, 2002, 2003, 2004, 2005 and 2006. You can also read through the grant-related postings to the Perl Foundation blog. As a general rule, a properly formatted grant proposal is more likely to be approved if it meets the following criteria:
- It has widespread benefit to the Perl community or a large segment of it.
- We have reason to believe that you can accomplish your goals.
- We can afford it (we rarely approve anything more than a couple of thousand dollars).
The thorniest issue, as always, is the grant amount. If you do not include a grant amount, the grant will not be approved. So how much do you ask for? While we have information in this posting about the grant committee, the reality is fairly simple. We're a non-profit organization and we are not flush with cash. If you charge us a typical hourly rate, we probably cannot afford it. Typical grant awards are generally in the $500 to $3000 range, but we have gone under and over those amounts, depending on the grant. As a general rule the less expensive it is, the more likely it is that we can afford to fund it. For highly speculative grants (in other words, projects whose benefits may be unclear or have a high chance of failure), we are unlikely to risk large amounts of our donor's money.
New address of my CGI Course.


text:
Phyllis Robertson Program
Robertson series presents Baker on 'green building'
The Schultz-Holmes Memorial Library in Blissfield, will present homebuilder, engineer, and environmental advocate Frank Baker, founder of Riverbend Timber Framing and Insulspan, Inc., as part of its Phyllis Robertson Program Series at 7 p.m. Thursday.
Baker will speak on "Green Building," a construction practice which seeks to minimize the environmental impact of both the process and the finished structure.
All library programs are free and open to the public.
Through Baker's career as an engineer at General Motors, founder/owner of Riverbend Timber Framing and Insulspan and currently as he is representing PFB Corporation on a number of national and international trade associations and non-profits, there has been a common thread, concern for the environment. Frank was building "Green" before the term "Green Building" came into common use to describe homes built to minimize the impact on our environment. He has also worked at … Read More »


text:
Jalopnik had the honor of test driving the RENNtech Mercedes C63 AMG SPEC.R. It's a beautiful car, but one of the most interesting features is the radar jamming system built into the rear-view mirror.
Amazingly enough, the system worked flawlessly in Jalopnik's test. The savings in speed tickets alone means that this car will pay for itself in time. Well...maybe not. Hit up Jalopnik to get the full test-drive details. [Jalopnik]


text:
A popular archipelago in the Atlantic Ocean that was first settled by the Portuguese in the 1420s, Madeira is famous for its wine, stunning landscapes, diverse wildlife, interesting culture, and long history.
Funchal (FNC) - beach life reigns supreme in this popular tourist hotspot, and you can ride on the Funchal Passenger Ropeway for amazing views of the area. A major local landmark is Funchal Cathedral.
Porto Santo (PXO) - combine relaxation and adventures with the island's beaches and caves, and explore the diverse aquatic life of the underwater world. Golfers will be happy with the choice of courses, and Pico Castelo Viewpoint provides a taste of the past as well as fantastic views.
Book your flights to Madeira without delay and have a fabulous trip coupled with enticingly low airfares!


text:
"C" Company Party - Roll out the barrel. Snow drops, and crocuses bloom in spite of the frost.
In 1939, at the outbreak of WWII and seven years after having been ordained to the priesthood, Rev. Michael Joseph Dalton (May 5, 1902 - April 6, 2009) volunteered to join the Essex Scottish Regiment of the Canadian Army.
Although he could have avoided front line service due to his age and position, he insisted that it was his duty to serve. Father Mike saw active duty in England, France, Belgium, The Netherlands and Germany.
Father Mike was known to work on the front lines of military combat and often marched with his men, carrying their weapons when they grew fatigued. He was known to drive his jeep, often against orders, to the front lines of combat in order to hear confessions
Saying Mass until his death - just one month shy of his 107th birthday - Father Mike was believed to have been the oldest Catholic priest in Canada and Canada's oldest surviving serviceman from World War II. Father Mike kept a war diary documenting his service during the years 1939-1946. In 1979 he donated it to the National Archives of Canada.
Please join me as I transcribe his writings online.
Subscribe to: Post Comments (Atom)


text:
How to invest with us?
New to online investments? Getting started is easy.
All you need to do is follow the following 6 steps. Please do not hesitate to Contact Us should you still have any questions after reading our instructions.
Step #1. Open an account with us.
You can open an account with us by filling out the 'Join Us' form located here. Please make sure that you fill in all the required fields.
Step #2. Open a
account. e-currency
Below are the instructions on how to open an account.
- Type www.payeer.com or www.wiredpay.com in your browser address bar.
- Click on the 'Create Account' link at the top of the page.
- Enter your contact email address and receive an account activation code in your mailbox.
- Fill out the account registration form and click 'Agree' button below.
- Retrieve your account number and Security PIN from your contact email address.
- Make sure you save your account number, Security PIN and Login PIN in a safe place.
Step #3. Fund your
Instructions for your Payeer or WiredPay account funding.
- Log into your an account by entering your account number, typing in your Login PIN and entering the turing number.
- Click on the 'Exchangers' button on the left-hand menu.
- Choose the exchanger provider you would like to buy PR or WP from and contact them to obtain payment instruction.
- Follow the instructions provided by the exchange provider.
Instructions for your BitCoin or LiteCoin account funding.
- Download BitCoin or LiteCoin e-wallet and open it.
- Choose the exchanger provider you would like to buy e-currency from and contact them to obtain payment instruction.
- Follow the instructions provided by the exchange provider.
Step #4. Log into your DiamondRain account.
Log into your DiamondRain account by entering your Username and Password in the appropriate area on our website.
Step #5. Deposit funds into your DiamondRain account.
To make a deposit you need to press the 'Make Deposits' button in the DiamondRain account and follow the instructions provided there.
Step #6. Start earning daily interest immediately. In addition, refer others and you will be able to receive referral commissions from their deposits.
- You will receive your first interest payment the next day.
- You can earn extra profit by referring other people to us. This can be done by providing them with your personal referral link that you can find in the 'Referral Links' area in your DiamondRain account.
These are the six basic steps which you need to take in order to get started with us. Should you have any further questions, please do not hesitate to contact us. Your questions and comments are always welcome.


text:
Since 1997, we've been producing and publishing amazing images of the hottest solo, and girl on girl erotica. It's anything but ordinary.
This is a truly unique feature that makes joining Digital Desire an experience above all other adult website experiences. Read from the producers of Digital Desire, what's on their minds, behind the scenes blips, and what's new and coming up.


text:
Maku'u Farmers Market
The market, managed by the Maku'u Farmers Market Corporation, is located on Hawaiian Homelands, makai of Highway 130 between Kea'au and Pahoa.
Among the colorful 'streets and avenues' of this market, you will find almost a little bit of everything; produce, value-added food products, ready to eat, baked goods and preserves, dairy products, meats and seafood on occasion, as well as plants (both food producing and ornamentals), crafts, clothing, tools, antiques and garage sale items.
We noticed this market has the largest variety of food producing trees and plants of all the markets we have visited to date.
The market is used also as an educational tool for youth to learn business, technical and job skills. Providing financial education, educational scholarships and cultural classes, the market also has limited free space for school fundraisers, and community resources; and for outreach/demonstrations/schools/non-profits and entertainment. From time to time, free classes and demos are offered, such as info on fire ants; sustainability and many other topics of public concerns.
This is also the only market we have visited so far that has a well defined "Food Court" with many vendors serving a variety of international foods; French Crepes, Mexican, Indian, Samoan, Greek and Thai. There is also a large tent with picnic tables adjacent to a stage set-up for the continuous live entertainment.
www.islandvalleydelights.com and have been kept busy there"Anita Roscoe, owner with husband Steve Roscoe, of Island/Valley Delights of Pahoa, have been selling for the last three years a variety of homemade breads, pastries, butter, jellies, jams and preserves as well as fresh eggs from their own chickens. Steve sells at the Volcano Market which is also on Sunday mornings. The couple also sells the bread through several retail locations."I learned to can and cook as a child, says Anita, and when my husband lost his business I decided it was my turn now. I started with just the jams then went to sweet breads. I saw yeast bread was needed and about one and a half years ago I started baking breads. We have since started a website
Anita says her best selling products seem to be jams, cinnamon rolls, banana bread and her sandwich bread. "I sell my breads at Abundant Life, Keaau Natural Foods, and Down to Earth. I also sell bread to Kaleo's, Black Rock Café, and to Ponds Restaurant. I sell my jams at KTA, Hilo airport, Kona airport, Honolulu Airport, and Down to Earth.
Anita enjoys sharing her products one on one and talking story. She especially loves repeat customers since they validate the joy she feels when she is creating what she sells.
Puna Goat Cheese is a product of the 9-acre Lava Rocks Farms in Hawaiian Acres in the Kurtistown area. Owned and operated by the husband and wife team of Steve Sayre and Lava Stacey, they have been selling 100% goat milk chevre, feta, queso fresco, ricotta and mozzarella at this market for the last 4 years. They also produce goat milk soaps and from time to time have baby goats for sale.
The first goat cheese farm in the state of Hawai'i, Lava Rocks Farm was originally established in 1984; it temporarily stopped production in 2000, and after reorganizing started operations again in 2005. At this point Steve and Lava are a little over the halfway mark of a 10- year plan to achieve at least 50% sustainability."We're very committed to the slow food movement and are mostly interested in making small quantities of artisan goat cheeses," Stacey says.
Their best selling product at the moment seems to be the goat cheese sold in jars filled with olive oil and herbs. You can find their products sold at many island markets and served at the most posh restaurants.We found Carlos Mojica of Kea'au by the delicious aroma wafting from his booth. Carlos and his wife Virginia own and operate Lucia's Mexican Food, and have been serving chicken and cheese Jalapeño tamales along with Mexican rice, refried beans and their special hot sauce for six years.
After samplng bits of both types of tamales, we could not make up our minds -- so ended up ordering both kinds. I thought the Jalapeño was going to be too hot for my taste, but was pleasantly surprised that although hot, there was a nice balance between the 'picante' and the cheese. At Carlos' suggestion, we added a bit of sour cream to the sauce.
Besides the food, they also serve iced cold Jugo de Jamaica (a red hibiscus drink very popular in Mexico) and Jugo de Piña (pineapple juice). Carlos is a very personable and friendly young man and we spent a nice time talking story with him.
Pali and Anjali Kala were busy cooking and dishing up home-style Indian food at their Kala's Indian Cuisine booth. They always offer at least one vegetarian and one non-veggie dish each market day. On the menu that morning were veggie samosas and chicken curry. The samosas were being sold as fast as Pali was making them.
Eating piping hot crusty chick pea and potato samosas seasoned with a touch of garam masala and a hint of cumin and served with a bit of cooling yogurt, cucumber and mint raita. . . . It can't get any better than that! Pali and Anjali moved to Hawai'i eight months ago from Cleveland where they ran a family Indian Cuisine business for 15 years. They have been selling at the Maku'u market for 7 months and hope to expand to other nearby markets soon.
Pali remarks that they love to hear people say they've been waiting for years for good and simple Indian food to come to Maku'u Market. He and Anjali are very happy to share "curry joy" with all who drop by their booth. This is not only our largest island market, but a very busy and eclectic one. As one vendor stated, it's a craft and food and garden and flea market wrapped into one. Plus it has live music and covered seating for eating and socializing. A true gathering of kama'aina.
Maku'u Farmer's Market
Sundays 8 am to 2 pm
Location: Approx 7-1/2 miles from Kea'au By-Pass - 15-2131 Keaau- Pahoa Hwy- On Highway 130 on the Hawaiian Homelands approaching Pahoa
Market Managers: Uncle John and Paula Kekahuna – 806-5537; Project Manager – Joane Kekahuna
Sponsoring organization: Maku'u Farmers Association
Type of Market: Open market: produce, value-added, ready to eat, plants, antiques/garage sale items, baked goods, dairy products, meats/seafood, crafts/pottery/art, tools, clothing
Date started: October 2001
How Funded: Booth rentals
Cost per stall/booth: Cost varies (see Manager)
Growth since started:
a. Number of vendors: Now, about 125
Geographical range of vendors: From all over the Big Island, outer islands and the mainland
Current Vendors:
a. Growing methods: From conventional to certified organic/hydroponic
b. Best selling products: Food, produce, plants, crafts/garage sale, clothing
Food crops in short supply: Seasonal crops: local mangoes, lychee
Other special features: Market site is an educational tool for youth to learn business, technical and job skills; financial education and educational scholarships, cultural classes. School fund raisers; limited free booth spaces available for community resource outreach/demonstrations/schools/non-profits, entertainment. Classes and demos such as info on fire ants; any public concerns
Sonia Martinez, the Hawai'i Homegrown Food Network regular farmers market reporter, is a cookbook author and freelance food writer for several publications in Hawai'i, including The Hamakua Times of Honoka'a. She is a contributing writer for Edible Hawaiian Islands Magazine and has her own food & garden blog at soniatasteshawaii.com.