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Get the latest public health information from CDC: https://www.coronavirus.gov
Get the latest research information from NIH: https://www.nih.gov/coronavirus
NIH staff guidance on coronavirus (NIH Only)
Excerpted from: NINDS Strategic Plan
The NINDS mission requires a balance of basic, translational, and clinical research. Physicians and scientists in academia and industry agree that basic research is essential for long-term progress against neurological diseases. Basic research seeks to understand how the nervous system develops and works and what goes wrong in disease. The private sector supports little basic neuroscience research because the return on investment in any specific line of research is unpredictable, even results that constitute major scientific advances may not yield marketable intellectual property, and the time between a basic finding and a practical application can be decades long. As a result, the NIH supports most basic medical research in the U.S. Although each NIH Institute and Center has a well-defined mission with respect to disease, several NIH components support complementary programs of basic neuroscience research that advance the missions of all. The NINDS has the largest neuroscience research budget of any NIH Institute or Center and so plays a crucial role in sustaining basic neuroscience research.
The NIH has a key role in supporting basic research to understand how the nervous system develops and operates, and what goes wrong in disease. Of all areas of research, basic research most benefits from the unfettered freedom of the research community to respond to scientific opportunity. Thus, investigator-initiated, peer-reviewed research is the foundation of the NINDS basic research program.
NINDS basic research is approximately equally divided between research on the normal development and working of the nervous system and research related to disease mechanisms. The cluster organization of the NINDS extramural program reflects the range of NINDS research. The program clusters focus on: ion channels, synapses, and neural circuits, which are the fundamental elements of the nervous system; the control of the environment of nerve cells by supporting cells; neurodegeneration, including the shared mechanisms of nerve cell death that contribute to many diseases; the role of genes in the normal and diseased nervous system; nervous system repair and plasticity, including stem cells, regeneration, and neural prostheses; and systems and cognitive neuroscience, which includes sensation, perception, movement, learning, memory, attention, thinking, and emotion. Maintaining this breadth of basic research is essential to the Institute's mission.
The Basic Module focused on basic science research, which provides fundamental understanding of normal nervous system function and disease mechanisms.
Read the full report (pdf, 1,698 kb)
Back to Basics
Back to Basics: A call for fundamental neuroscience research
New NINDS Funding Announcement Aims to Spur Basic Neuroscience Research
New NINDS Funding Announcement Aims to Spur Basic Neuroscience Research
Basic science: Bedrock of progress
Basic science: Bedrock of progress
NINDS Supports Outstanding Projects Using Invertebrate Model Systems
Transformative basic research at NINDS: A case for invertebrate models systems
Within the Division of Extramural Research, Program Directors are organized within a series of scientifically-related research Clusters that reflect the breadth of the research programs supported by NINDS. Within each Cluster, Program Directors oversee the basic research activities and, in coordination with the NINDS Office of Translational Research and Office of Clinical Research, coordinate the translational and clinical research in one or more parts of the Institute's research funding program, managing a portfolio of grants and contracts and coordinating program efforts in these specifically defined areas of neuroscience research. To find contact information related to specific research, please refer to our list of Program Directors.
Channels, synapses, and neural circuits are fundamental structural and functional elements of the nervous system. Detailed and integrated knowledge of these elements is essential for understanding how the nervous system works under normal and abnormal conditions. In recent years, remarkable progress and exciting discoveries have been made in the basic research in these areas; only few of them, however, have been directly connected to mechanisms underlying the causes of numerous neurological disorders. The major goals of our program are 1) to continue to support the ongoing basic and clinical research; 2) to foster research on particular channels, synapses, and neural circuits that have immediate medical relevance; and 3) encourage translational research that links the discoveries from basic research into medication development and therapeutic interventions for treating neurological disorders, such as epilepsy. Topics of research supported by the Channels, Synapses, and Neural Circuits cluster include neural circuit analysis, synaptic transmission, synaptic plasticity, structural analysis of neuronal membrane proteins, channelopathies, and epilepsy. The cluster supports basic and translational research, as well as clinical trials, and facilitates multidisciplinary collaborations.
Serious Adverse Drug Reaction Research (R01)
Release Date: 2016-05-19, Contact: NINDS Funding Coordinator, [ (R01) PAR-16-275 ]
Neurological disorders may result when extra-neuronal cells are compromised, as in demyelinating and cerebrovascular diseases; when extra-neuronal cells themselves become aggressors, as in inflammatory responses within the nervous system; when cells of the nervous system become cancerous and form tumors; when viruses, bacteria, or parasites infect the cells of the nervous system; when autoimmune responses damage nerve and muscle; or when cells of the blood-brain barrier are dysfunctional. Glial cells, microvascular endothelia, and cells of hematopoetic origin are integrally involved in the normal development and/or functioning of the nervous system and play a crucial role in disease. Emerging concepts on the interaction among all of these cells hold great promise for increasing our understanding of how the nervous system works in normal and diseased states, and will broaden our perspective on how we think about the nervous system.
The Neural Environment cluster promotes translating scientific knowledge into useful diagnostic tools, research on the implementation of preventive measures, and development and delivery of targeted therapeutic agents for neurological diseases.
Research areas supported by the Neural Environment:
The disease areas supported by Neural Environment cluster include: stroke, multiple sclerosis, CNS and PNS tumors, neuro-AIDS, prion diseases, and CNS infections. The Neural Environment cluster also supports several areas of basic neuroscience research including: neuroimmunology, neurovirology, neural vascular biology, and the blood brain barrier. Our grant portfolio spans basic, translational, and some clinical research.
The Neurodegeneration cluster portfolio consists of research on adult onset neurodegenerative diseases of all types, broadly focusing on pathogenesis, treatment and prevention. Research on the normal structure and function of neural systems is also included to enable identification of intervention strategies. The role of the programmatic team is to develop, implement and manage these research programs and to promote the translation of research findings into clinical practice. Included in the portfolio are topics such as neuronal cell death, protein misfolding, aggregation, processing, mitochondrial pathologies, epidemiological studies, genetic studies, biomarker studies, clinical studies, including deep brain stimulation and gene therapy, and translational projects that will accelerate bench-to-bedside therapies for neurodegenerative disorders.
Genetic methodologies are having a rapidly increasingly impact on studies of the normal and diseased nervous system. To date, more than 200 genes have been identified that cause or contribute to neurological disorders. It is essential that neuroscientists exploit the power of modern molecular genetics and use the information becoming available from sequencing of the human genome.
The Neurogenetics cluster supports research of genes that cause neurological disorders; molecular mechanisms through which disease genes act; animal models and in vitro techniques for studying pathways of gene function; genetically-based studies of neuronal patterning, migration, connectivity, and cognitive/behavioral function; and the genetic basis of normal neural development and function. The cluster promotes collecting family data and applying molecular genetic methodologies for gene identification, and development of gene-based therapeutics for neurological disorders and pharmaceuticals targeted to specific gene products. The Neurogenetics cluster also develops resources for neurogenetics research, such as tissue and information registries, atlases of gene expression and function, and mutagenesis and phenotyping methodologies.
Repair and Plasticity supports research in spinal cord injury, traumatic brain injury, recovery of function, plasticity of the nervous system, neural circuits that underlie specific behaviors, repair of the nervous system in injury and disease, stem cell biology, neural prosthesis, neuroengineering, and other means of repairing the nervous system in injury and disease.
Our Mission
To understand mechanisms of plasticity in the healthy nervous system and explore implications for repair.
To develop interventions to modify the course of injury and disease progression and improve functional outcome in individuals following injury to the nervous system.
To understand the course of degeneration and repair following spinal cord injury and brain injury on timescales ranging from seconds to years.
To understand the role of endogenous neurogenesis as well as stem and progenitor cell biology in the development and repair of the nervous system.
To promote the development of neural prosthetic devices designed to restore function after neurological injury or disease.
The Systems and Cognitive Neuroscience cluster supports research focused on higher brain functions that underlie complex behavioral phenomena such as learning, memory, attention, language, cognition, sensation/perception, movement, the wakefulness-sleep cycle, and pain. These phenomena depend on the integrated functioning of neural circuits and systems. Funded research involves human or animal subjects or computer models of neural circuits. Research methods include non-invasive imaging of brain structure and function (e.g., EEG, MEG, PET, MRI) and advanced methods for recording neural structure and function associated with specific cognitive and behavioral processes in vivo and in vitro.


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Magnolia Drive
Magnolia Drive
What is this project?
The crew will replace 725 feet of sidewalk on the north side of Magnolia Drive from Azalea Terrace to Ashbrook Drive.
Why is it important?
The project will eliminate tripping hazards there and will make the sidewalk and driveway approaches ADA compliant.
What is the current status?
This project is complete.
How is this project being funded?
Funding for this project comes from the Street Fund. The Street Fund is financed through two sources:
1) Turn-back revenues from the State of Arkansas. The State collects motor fuel taxes, which are returned to the City on a per-capita basis.
2) Turn-back monies received from the County Road Millage Tax. The City receives 80% of the road millage levied by the Quorum Court on real and personal property located within the city.
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Honey Breeze String Body
Modern and light: The silky jersey material, combined with a ribbed finish on the hem of the plunging V-neck, makes this string body a real all-rounder. The top section, featuring a wraparound effect, is wonderfully light, while the figure-hugging panty section vanishes discreetly under any outfit.
• Close fit
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• Machine washable
Summer style.
Order Today: Estimated Delivery Date 23/10/2020
- main material 86% nylon, 14% elastane
- hem 67% viscose, 33% polyester


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New York drivers are about to see the penalty for texting while driving increase from three points to five points off their driver's licenses.
Gov. Andrew Cuomo said a Manhattan press conference Friday that the change will go into effect starting Saturday. The penalty applies to any kind of cellphone activity while driving.
Cuomo's also proposing legislation that would impose tougher sanctions against probationary and junior drivers for texting.
Under that proposal, violators' licenses would be suspended for 60 days after their first conviction.
Cuomo said he spends a lot of time in a car and he sees people texting while driving every day.


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State pension systems, which represent the retirement security of millions of American public workers, spent some $7.8 billion in management fees in 2011, according to a new study by the Maryland Tax Education Foundation.
Yet, evidence is lacking that active management provided public pensions higher investment returns, according to the study.
It noted that 84% of actively managed U.S. equity funds underperformed their benchmarks during 2011, citing S&P Indices and Morningstar.
The report said the vast majority of U.S. public pension systems contract with Wall Street firms to select the publicly traded stocks and bonds that make up the bulk of their investment portfolios.
"The firms' typical 'sales pitch' to a pension fund is that the Wall Street firm can 'outperform' a given section of the stock or bond market; therefore, the pension fund should pay the Wall Street firm a fee for the firm's stock (or bond) picking prowess."
The foundation reviewed comprehensive annual reports for statewide retirement systems in all 50 states in order to determine the ratio of state pension system fees paid to Wall Street to their net assets.
The U.S. average was 0.409, and the median was 0.359. The states with the highest fee ratios were the following:
The report said many states indexed only a small portion of their portfolios to public indexes. Extending this practice to 80% or 90% of their portfolios would provide annual savings in excess of $6 billion, it said.


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Fresh on the metal heels of last week's insanely spoilery on set Iron Man 3 set photo, Marvel has released the very first "official" Iron Man 3 picture. Which shows Tony Stark taking in his vast collection of Iron Man suits.
We can't wait to see the latest model! (And if the rumors are true, then the next version of the Iron Man armor could be something very, very different.)
The images was taken from the @Iron Man twitter account. Which hasn't been officially certified by Marvel, yet. But we suspect that will change soon.


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The New American Bible Compact Edition is a light and portable version of Oxford's popular Catholic bible. Durable binding, compact size, and supremely affordable value make this a perfect edition for school and church use. The Compact Edition is available in a range of vibrant colors and elegant bindings. Printed on smooth, durable paper in a clear typeface and easy-to-navigate format, the NAB Compact Edition is easy to use and fits perfectly in a purse or bag. The NAB Compact Edition is still packed with all the features that make Oxford NAB volumes the best Bible versions available. The slim, portable bible features the Dogmatic Constitution on Divine Revelation (Dei Verbum), placement of the NAB notes at the end of each book to enhance the readability of the biblical text, a select NAB Concordance, an essay on using the Lectionary, a table of Weekday and Sunday Lectionary readings, and a table of Weights and Measures in the Bible.Oxford is the author of 'New American Bible Black/gray, Pacific Duvelle', published 2004 under ISBN 9780195282924 and ISBN 0195282922.[read more]
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Veterans are so much more than heroes. They're intelligent and experienced leaders who deserve recognition for both their service to our country and the valuable strengths they bring to the civilian workforce. Not only do service members bring unique leadership skills and work styles to our organization, they also share our values and passions. That's why we're committed to attracting, retaining and developing both active and veteran members of our armed forces.


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Seattle: 5 Great Brunch Cocktails to Drink This Weekend
In other cities, brunch is the norm at restaurants of note, whereas here in Seattle, it is so uncommon that a recent Seattle Times article highlighted the basic fact that places were actually serving the mid-day meal. Perhaps it's the ski slopes and hiking trails that keep brunch doors shuttered, or maybe that pesky rain the city's famous for keeps eaters out of long lines. French toast and Eggs Benedict might not be inspiring the city to drag itself out of bed, but those who are in the know realize there's a better reason to head to brunch: Seattle's restaurants offer a world of cocktails beyond the clichéd Bloody Mary or Mimosa, all designed to open eyes (and justify pre-noon drinking).
Brunch cocktails walk a fine line, encouraging the drinker to get up and get moving while offering a gentle prod out of sobriety. Coffee makes an excellent vehicle for pepping up a drink, both in its natural form, mixed with Fernet Branca and topped with Angostura whipped cream at Sun Liquor, and in infusions like the Pacific Northwest coffee bitters used in Ba Bar's Rummy Saz. Other tipples take a hint from the classic mimosa and shake the drinker awake with friendly bubbles. Citrus plays a strong role in brunch cocktails, bringing its sunshine-y spritz and offering a bright, acidic touch that makes it food-friendly.
And as far as food goes, we're not just talking scrambled eggs. These drinks are part of a complete, creative meal: a sip of Ma'ono's Currant Affair makes one marvel at how well it pairs with the saimin (Hawaiian-style ramen), while Tolouse Petit's Naked if I Want To balances out the richness of their New Orleans-style shrimp and grits. While Seattle may not be a big brunch town (yet), it's not for lack of adventurous food or inventive cocktails. Follow the map to morning-buzz bliss or click through the slideshow for a look at five Seattle brunch beverages that still haunt our day-drinking dreams.
Your Seattle Brunch Drinks To-Do List
Currant Affair at Ma'ono Fried Chicken & Whisky
Rummy Saz at Ba Bar
Cheery Pie at Burgundian
Cafe Amaro at Sun Liquor
Naked if I Want to at Toulouse Petit
All products linked here have been independently selected by our editors. We may earn a commission on purchases, as described in our affiliate policy.


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P.O. Box 12068, State Capitol
Austin, Texas 78711
Tel. (512) 463-0112
December 17, 2003
AUSTIN - Senator Jane Nelson, R-Lewisville, will join local celebrities Scott Murray and Larry North in Hurst on Saturday for a holiday celebration for families affected by domestic violence.
The event, sponsored by the Battered Women's Foundation, takes place from 10 a.m. to 3 p.m. Saturday, December 20, at the Word of Love Church, 1860 Precinct Line Road in Hurst. More than 800 people are expected to attend the event featuring door prizes, gifts and a visit from Santa Claus. One lucky mom will drive away in a car donated by A-1 Auto.
"The holidays are a time for family, and unfortunately there are families here in our community whose lives have been turned upside down by violence in their home. Many of these individuals are spending their first holiday on their own, and I am so grateful for the opportunity to spend some time with these brave women and let them know that they are not alone this fight," Senator Nelson, who has sponsored several anti-domestic violence laws, said.
Established in 1995, the Battered Women's Foundation provides sanctuary and support for victims of domestic abuse and their children. More than 1,500 individuals have been served by the foundation this year.
"It is going to mean so much to our families to have people like Senator Nelson, Scott Murray and Larry North to spend this time. These truly are remarkable women who have risked everything and overcome enormous obstacles to put their lives on a better path," Brenda Jackson, the foundation's director, said. "There is still time for others in the community to adopt a Christmas angel for this event, and we welcome any support for those in the giving spirit."
NOTE: Due to privacy concerns, some women attending Saturday's event may elect not to be interviewed by reporters.


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Seniors Enquiry Line is funded by the Queensland Government and operated by UnitingCare.
The materials and information included on this website are provided as a service to you and do not necessarily reflect endorsement by the Seniors Enquiry Line Program. The Seniors Enquiry Line is not responsible for the accuracy of information provided from outside sources. The information provided is a guide only and should not be substituted for independent legal advice. Groups and workshops promoted on this website are for your information and are not coordinated by or connected to Seniors Enquiry Line Program in any way unless specified.


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MLK Day and Presidential Inauguration a Historic Occasion to Stand Up for Social and Economic Justice, Says NEA President
NEA remains committed to a future filled will hope, opportunity and prosperity for students
WASHINGTON - January 19, 2013 -
"On Monday, our nation's first African American President will take the oath of office—the same day we honor Rev. Martin Luther King Jr, our most impassioned and celebrated civil rights leader. This convergence amplifies the importance of both events, and carries special meaning for National Education Association members who have stood up for social and economic justice throughout the organization's proud 155-year history.
"As President Obama begins his second term, the National Education Association is committed to restoring hope and bringing about change in our country by fighting for greater access to opportunity for all Americans. For too long, opportunity has been the province of a select few, while average Americans have been left behind. It's time to address these inequities and restore fairness.
"Our democracy is built upon the notion of opportunity, which rests upon the foundation of public education. We must work together to strengthen that foundation so that all students—no matter their zip code, race or social class—have access to a high quality education, a learning environment that is healthy, safe and secure, and a community that supports them and their families, both on and off school grounds.
"Recently, we've seen firsthand how our educators have so dramatically given their whole hearts to their students. In addition to caring how well their students learn, they also care about their students' well-being and the well-being of their families. The personal commitment we've seen in our educators, from the school bus drivers who rescued victims of flooding after Superstorm Sandy to the classroom teachers who sacrificed their own safety to protect the lives of their students at Sandy Hook Elementary, will be reflected in NEA's renewed commitment to educational excellence, social justice, and economic fairness. We know that the pathway from poverty to America's great middle class runs through the classrooms of public schools and institutions of higher education. We will always fight for the educational opportunities that erase achievement gaps. We will always stand side by side, students, parents, and educators, to make sure our voices are heard in the places where policies are made and jobs are created.
"Along the way, we will be guided by a George Bernard Shaw quote that continues to inspire me: 'Some men see things as they are and asky why. Others dream things that never were and ask why not.'
"On this important historic occasion, and on behalf of public school students across the nation, the National Education Association remains committed to dreaming and asking 'why not?' so that every public school student can look forward to a future filled with hope, prosperity and opportunity."
Visit educationvotes.org to learn more about NEA's efforts to expand opportunity in our economy, our schools and our democracy.
The National Education Association is the nation's largest professional employee organization, representing more than 3 million elementary and secondary teachers, higher education faculty, education support professionals, school administrators, retired educators and students preparing to become teachers.


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The ERS/Envisat (A)ATSR dataset is available through the ATSR MERCI system.
Both http and ftp access are available to this product set that has been processed with the same algorithm and so represents a homogeneous product set from August 1991 to April 2012 (ref 3rd reprocessing).
FTP users can download all ATSR-1, ATSR-2 and AATSR Level-1b and Level-2 products in Envisat format (TOA_1P, NR_2P, AR_2P and MET_2P).
Additionally, FTP users also have access to the L2P and L3U products providing (A)ATSR data in NetCDF-4 format.
For all three ATSR instruments, Level-1b and Level-2 products (TOA_1P and NR_2P) can also be browsed through the ATSR MERCI interface which allows users to select geographical areas of interest and search for products for specific periods of time.
See related news on the (A)ATSR 3rd Reprocessing of 13 December 2013.
As a demonstration, global SST (Sea Surface Temperature) Level 3 products from AATSR from September 2002 to January 2005 have been generated at two spatial resolutions, 10 arcminutes and 30 arcminutes. The data are provided in 2 formats, PNG (Portable Network Graphic) and HDF (Hierarchical Data Format).
MERCI is a web-based application that provides access to the complete Envisat MERIS Level 1 (MER_FRS_1P) and Level-2 (MER_FRS_2P) Full Resolution Full Swath data archive.
The MERCI regional extraction tool allows for search on a specific timeframe, definition of geographical area and visualisation of available products and quick looks. Bulk download of selected files is also possible.
The MERCI file archive contains the bulk processed MERIS FRS Level 1 and Level 2 products covering the period from 17 May 2002 to 08 April 2012. The same dataset is also available via nominal FTP.
Yearly and global density maps are available to get a better overview of the MERIS FRS coverage.
Related news:
MERIS L1 FRS data availability - 20 December 2013
Complete Envisat MERIS FRS L1/2 dataset available online - 13 February 2015
MERCI is a web-based application that provides access to the complete Envisat MERIS Reduced Resolution (RR) 3rd reprocessed dataset (mid-2002 to April 2012).
It allows the selection of a geographical area, the visualisation of the list of available products and quicklooks, and the download of one or more file extractions corresponding to the time and area of interest.
For information on the content and quality of the reprocessed data, please see the MERIS SPPA Webpage and the MERIS 3rd data reprocessing - Reprocessing Changes document. (PDF 20.5 Mb)
Taking advantage of the Level 2 MERIS data re-processing, a number of demonstration MERIS Level 3 products have been generated for the complete mission. They have been processed using the standard Level 2 products processed with the last processor version.
The GlobCover system is an automated global classification chain based on ENVISAT's MERIS FR 300m. Level 1B data covering the period between December 2004 and June 2006. The product consists of a global mosaic and eleven regional mosaics, accompanied by the relevant documentation, legend and colour maps.
The CHRIS and HRC data available from ESA can be browsed from the PROBA on-line archive. In order to identify quickly the file of interest, the server is sortable by name, date and site. New data are regularly transferred to the ESRIN server after processing by SIRA/UK.
The Kompsat-1 European cities dataset is available from the ESA Kompsat on-line archive.
In order to identify quickly the file of interest, the server is sortable by name, date and site.
Image2006 European coverages are collections of SPOT and IRS 20/25m resolution orthorectified multispectral products with 60km/140km swath, composing 2 cloud-free coverages of 38 European countries in the Reference Year 2006 (+/- 1 year)


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Let's Make a Geopolitical Deal
Paul Mapp: 'The Elusive West and the Contest for Empire, 1713-1763'
When the diplomatic dust had settled following the 1713 signing of the Treaty of Utrecht, officials in Europe's imperial capitals got back to talking about extending their empires into uncolonized areas of western North America. And they had little idea of what they were talking about.
In fact, Paul Mapp describes the North American imperial efforts of France, Spain and Britain as a geopolitical version of the old game show "Let's Make a Deal."
"I don't know if you ever saw it, but you could take the money or you could take the curtain. And you never know what's behind the curtain. You could get something really valuable, or you could get a lifetime supply of Eskimo Pies," he said. "The American West was the curtain."
That's the theme of Mapp's new book The Elusive West and the Contest for Empire, 1713-1763. In August, Mapp, associate professor in William & Mary's Lyon Gardiner Tyler Department of History, was reading page galleys for The Elusive West, which is being published by the the University of North Carolina Press for the Omohundro Institute of Early American History and Culture. The book itself was out just before Thanksgiving.
Geographic ignorance
"During the first two-thirds of the 18th century, almost the entire western two-thirds of North America were largely unexplored—unknown to Europeans," Mapp said. The Elusive West documents the geographic ignorance of these Europeans and also gives the 21st century reader plenty of context to grasp the implications—and also to understand how the great powers of the world got it so wrong in the first place.
The Treaty of Utrecht had given the Spanish Empire exclusive access to the Pacific, Mapp said. But both France and Britain knew that Spain was bringing silver out of South America by the galleon-load. Neither wanted to miss out on the various opportunities for advancement in the Pacific, beginning with trading concessions. Mapp noted that French traders had done some under-the-radar business with ports in Peru and Chile early in the 18th century, moderate in scale—but yielding impressive amount of Spanish silver.
"France is intimately aware of the financial payoff of getting into the Pacific," Mapp said. "The Spanish empire is trying to have a closed market, and the British want into it, too. Legally or illegally, they want in."
French and British ships had another barrier to the Pacific: the long trip around South America with no friendly ports for refitting and resupply. "The thing about this Cape Horn route, which everyone was using for a while, is that it is extremely difficult and dangerous," he said. "Ships get lost; it's a nightmare."
Discouraged from Pacific adventures by the twin barriers of geography and diplomacy, Spain's two imperial rivals try a series of end runs. Mapp notes that the French and British attempts to get to the Pacific and make use of it are important drivers of international relations in Europe throughout the period.
One of the problems is that neither the British nor the French knew where the Pacific was—at least in terms of distance overland from their colonies in Virginia and Quebec. The Spanish, Mapp said, really had no better idea.
A larger land mass than everyone thought
"If you look at some of the maps from the period, you will see they often cut North America off a long way short of where we know the Pacific actually is," Mapp said. Such underestimation of the land mass brought inevitable disappointment to anyone trying to find the Northwest Passage. That Holy Grail of North American exploration—sought by everyone from John Cabot to John Smith—became the subject of renewed interest on the part of all the imperial powers, he said.
He explained that such geographic ignorance had greater implications back home, as ministers formulating foreign policy played Let's Make a Deal for big stakes. "If you are sitting in Paris or London, and you don't know whether Hudson's Bay is connected to the Pacific, how do you assess the value of Hudson's Bay?," he asks.
Even more important than the great powers' geographical ignorance per se were their mutual fuzziness when it came to what the other nations knew about the American West—and what the imperial intentions of their rivals were. Another important aspect was the fact that the rivalry for North American conquest was among three, rather than two, great imperial powers.
"It gives you different possibilities for alliances," he explained. "For Spain, initially, it is an advantage that both Britain and France are in the New World because you could get them fighting each other and not you. It makes things more complicated."
The three-way imperial rivalry came to a head in the Seven Years War between 1756 and 1763, which Mapp says was initiated by a "series of events involving the British and various outposts of the French empire." (Young George Washington, the ink still wet on his surveyor's license from William & Mary, is prominent in these events: "He goes west to the Appalachians," Mapp says, "and gets mixed up with various things—surveying, carrying messages, shooting French people.")
The French push back
Mapp notes that the French devoutly want to avoid a war with Britain. But uncertainty about British intentions—coupled with geographic ignorance—led the French to believe the British had their sights on access to the American West and Pacific, assets held since the Treaty of Utrecht by the comparatively weak Spanish.
"The conclusion of the French was that we need to stop these British guys. We have to push them back, not let this imperial design unfold," Mapp said. "So, if the British are pushing in the Ohio Valley, the French push back. That mutual pushing led to a lot of people getting shot."
The Elusive West is an expansion of the subject matter of Mapp's doctoral dissertation, trying, he said, to answer this question: "How do you compete for North America, when you don't really know what North America is?" He points out that, in addition to their North American adventures, all the players had other imperial irons in the fire around the world and had to allocate resources based on a kaleidoscopic array of information and misinformation.
"You always hope for a simple answer," Mapp said, "but you end up with a complicated one."


text:
Gregory J. Fleming
Gregory J. Fleming is president of Morgan Stanley Smith Barney and Morgan Stanley Investment Management. He has worked for the firm since February 2010 and serves on its operating committee.
Previously, Fleming was president and chief operating officer of Merrill Lynch. Prior to that, he was executive vice president and co-president of Merrill's global markets and investment banking group, where he advised leading global corporations, financial institutions, asset management firms, financial sponsors and hedge funds. He started in investment banking in 1992.
He also has been a principal at Booz Allen Hamilton.
Fleming was a senior research scholar and distinguished visiting fellow at the Center for the Study of Corporate Law at Yale Law School.
He is a governor of the Financial Industry Regulatory Authority; a member of the Council on Foreign Relations; a director of Colgate University; a member of the board of advisers for the Yale Law School Center for the Study of Corporate Law; and a trustee for the Rippowam-Cisqua School of Bedford, N.Y. He is also a former board member of BlackRock.
Fleming graduated with a degree in economics from Colgate University (Phi Beta Kappa, summa cum laude) and has a J.D. from Yale Law School.


text:
I'm so glad my cousin Ryan had an awesome waterproof camera that also takes quick action shots. I'm sure there is technical terminology for all of this but anyway, check out these pics!!
I LOVE cliff jumping. It was a little different into the Colorado River though. The water was so cold it takes your breath away when you first get in. And even though in the pictures it doesn't look like there's much of a current, it was strong enough to start pulling you down the river before you could even reach the surface again. It was so fun!
This is a picture of us up on Sand Dune Arch. It was quite the climb to get up there. Brandon climbed up and then literally pulled me up there. It was cool.


text:
With its fog-ensconced settings, brilliantly deranged creature designs and use of allegory to probe characters' psyches, 1999's "Silent Hill" was the first survival horror game to explore true psychological terror. Many fans worried this newest entry in the series, the first developed outside Japan, would favor a more American emphasis on action at the expense of mood. But "Silent Hill: Homecoming" is a true heir, lovingly crafted with the same psychological intensity as its predescessors while improving on their weak combat controls. All but the most closed-minded afficionados are sure to embrace it and savvy marketing by Konami could expand the fan base.
"Homecoming" follows in the series' tradition of casting an emotionally unsettled protagonist into a disturbing wasteland that suggests allegories to the personal Hell in his mind. Developer Double Helix's steepest challenge — and therefore its greatest achievement — is the game's thematic consistency, drawing identifiable relationships to the four previous "Silent Hill" console titles and even the regrettable (if visually correct) film — though fans will be glad to know it doesn't take very many cues from the latter.
This time, players follow traumatized war veteran Alex Shepherd, who returns after a long hospital stay to his family homestead in the neighboring town of Shepherd's Glen, where he discovers his younger brother Joshua has disappeared.
But all is not as he remembers. Shepherd's Glen is visualized in stunning decay, shrouded in the unsettling white fog that is the series' hallmark and overrun by horrifying creatures, and Alex soon learns Joshua is far from the only person who has gone missing. His search for his brother and the truth leads him through decrepit locales and nightmarish hallucinations where Joshua — who flees from Alex with haunted, sullen eyes — is always just a step out of reach.
This homecoming of a prodigal son to the poignant, painful family history he left behind quickly reveals itself to be about deeper things than a supernatural horror mystery. "Silent Hill" has always been rich with subtext, but never has it been so subtly yet satisfyingly knit as it is here. Though the game never surrenders the sprawling surrealism loyalists expect from the franchise, it's admirably well-paced, leading the player through a strong storyline that ends with a stunningly unpredictable conclusion.
All of the game's gore-laced environments — especially the hallucinatory, gruesome Hell-world that parallels them — are stunningly realized, hauntingly lived-in, and so dense with subtle details that players will find themselves looking closely, with horrified fascination. The hyper-sexualized, faceless and stilted nurses who are a "Silent Hill" mainstay are back, along with ashen-skinned, split-headed horrors and red-glistening, skinless hellhounds.
"Homecoming" does place a greater emphasis on fights with weapons like a pipe or crowbar than in prior games. The controls are cumbersome at times, but they add a welcome layer of complexity to the traditional focus on environmental exploration. A generous "continue" option is sure to please those less apt at melee fighting who will often die in the game's more challenging second half.


text:
A Boone County judge has granted what apparently is the first same-sex divorce in Missouri, which has a constitutional amendment against recognizing same-sex marriages.
Boone County Circuit Judge Leslie Schneider granted a divorce last month for Dena and Samantha Latimer, who were married in Massachusetts in 2009 and lived in Columbia. The Columbia Daily Tribune reports Schneider ruled that a Missouri court can recognize the law of the state where the marriage was performed "for the limited purpose of granting equitable relief."
Tana Benner, a Columbia lawyer who represented Dena Latimer, said the Latimers were pleased the judge granted the divorce.


text:
Thursday, February 10, 2011
My Gluten-Free January
I succeeded in avoiding all gluten for the month of January, even though it was a pain at times. I felt good before January, and didn't start with any health or body weight problems, so there wasn't much to improve. I also felt good while strictly avoiding gluten this January, perhaps a little better than usual but it's hard to say.
At the end of the month, I did a blinded wheat challenge using the method I described in a previous post, which uses gluten-free bread as the placebo (1). I recorded my blood sugar at 30 minute intervals after eating the bread, and recorded how I felt physically and emotionally for three days after each challenge.
The result? I think the bread gave me gas, but that's about it. I'm not even positive that was due to the wheat. My energy level was good, and I didn't experience any digestive pain or changes in transit time. There was no significant difference in my blood glucose response between the bread and the gluten-free bread.
I decided that I didn't have any symptoms, so I celebrated by having a porter (1) with friends a few nights later. I slept poorly and woke up with mild digestive discomfort and gas. Then I ate wheat later in the week and slept poorly and got gas again. Hmmm...
Some people might say that the body adapts to any food, and wheat is no different. Go without it for a while, and the body has a tough time digesting it. But I can go for weeks without eating a potato, a chicken thigh or broccoli, and all will digest just fine when I eat them again.
I'm pretty sure I don't have a severe reaction to gluten. I think I'm going to stick with my mostly gluten-free habits, and eat it occasionally when I'm offered food in social situations.
Did anyone else do a blinded wheat challenge? Describe it in the comments!
50 comments:
- Markus said...
"I slept poorly and woke up with mild digestive discomfort and gas."
That is pretty much the exact same things that I experience when I occasionally eat some wheat or gluten containing food.
- February 10, 2011 at 11:17 PM
For about a year now, whenever I go out with friends for adult beverages, I only consume liquor (mostly rum) because I noticed beer was making me ill.
A couple nights ago I went out to watch a game, and since I was watching my spending I had beer instead of liquor. Not any great amount, mind you - just while watching the game. The next morning when I got up you'd have thought I'd gone on a bender. My head was cloudy, stomach had me running to the bathroom every half hour. Beer was the only part of my day that differed. Guess I'm back off it.
- February 11, 2011 at 2:12 AM
- scottrhamilton said...
Have you experimented with bread made from the Einkorn vareity of wheat?
I have read on other blogs that the blood suger response is signinfcantly
better (110 vs: 170) when using this variety of wheat.
- February 11, 2011 at 2:17 AM
- Jenny said...
The only reason that the bread gave you gas was because you downregulated some hormones while not eating gluten. After a few days they come back and you should be fine.
I went gluten free for several months some years ago, and when I started it up again noticed no difference.
Gluten intolerance, like lactose intolerance, is a real problem for some people, but it is turning into yet another of the huge demonization fads that sweep through the nutrition community every couple years. And what is really sad is that the "health food" merchants are filling the stores with very high carb "gluten free" foods which are being promoted as healthy and will do nothing for the health of people who aren't in the minority who are gluten sensitive except make it worse by raising their blood sugars.
- February 11, 2011 at 4:48 AM
- Unknown said...
+1 Jenny.
I don't see Brussels sprouts, broccoli, or any other gas-creating food being demonized.
Lots and lots of good reasons to cut down the amount of wheat compared to S.A.D. Very few reasons to go "gluten-free". As I've said before, if you think you're gluten intolerant, see a psychologist.
Quality also matters. I regularly eat good quality french bread (a baguette a week), oatmeal, soy sauce, and pasta. In a pinch this week got a frozen supermarket pizza -- my god, the pain afterwards! Now, whether it was gluten, poor quality wheat, bad microwave cooking, or food poisoning I'll never know. But the key thing is don't buy crap food!
- February 11, 2011 at 6:00 AM
+1 Jenny.
I don't see Brussels sprouts, broccoli, or any other gas-creating food being demonized.
Lots and lots of good reasons to cut down the amount of wheat compared to S.A.D. Very few reasons to go "gluten-free". As I've said before, if you think you're gluten intolerant, see a psychologist.
Quality also matters. I regularly eat good quality french bread (a baguette a week), oatmeal, soy sauce, and pasta. In a pinch this week got a frozen supermarket pizza -- my god, the pain afterwards! Now, whether it was gluten, poor quality wheat, bad microwave cooking, or food poisoning I'll never know. But the key thing is don't buy crap food!
- February 11, 2011 at 6:01 AM
- Tucker Goodrich said...
I've done some inadvertent blind challenges. I ate a sushi roll that had soy sauce in it. Most soy sauces are made with wheat.
Within minutes of finishing lunch I had shooting cramps in my stomach. I went back and checked the ingredients on the sushi roll, and, sure enough...
I had a similar experience with fish from a local Japanese market. They seem to have prepared their salted fish with soy sauce that day. I had a huge and immediate wheat reaction, including stomach, intesttinal, and then bowel cramps, tiredness, a head rush, and all the other symptoms I've come to recognize.
To Jenny's point, you're not "downregulating some hormones". There are chemicals in wheat, like WGA, that have toxic effects on your body. This occurs in all people, not just "gluten sensitive" people. Various papers in the scientific literature have found this effect. I don't think it's a fad. Every person but one I have personally convinced to go gluten-free for a week has had a reaction of some sort when they tried it again. Some have had violent reactions.
If that happened with any other food you'd call it food poison. For some reason with wheat it's considered normal? That makes no sense.
I think Dr. William Davis has nailed it, Norman Borlaug hybridized wheat and made it more pest-resistant. From wheat's perspective, we're a pest.
- February 11, 2011 at 7:04 AM
- perrygeo said...
- This comment has been removed by the author.
- February 11, 2011 at 7:09 AM
- perrygeo said...
Even for folks without clinical gluten intolerance, gluten-free is probably a good idea - simply because we don't experience the symptoms to a crippling degree doesn't mean its good for us!!
Every once in a while I eat some gluten containing foods and get the bloating with visible inflamation and redness. My wife notices it immediately the next morning and calls it "puffy beer & pizza face". Its tolerable but clearly a sign that my body is not pleased. Eating gluten-free pizza and beer, I don't get the same symptoms. I could continue living my life ingesting a mild poison - it probably won't kill me - but I simply prefer to eat things that make me feel good. If that's a 'fad' to eat quality foods that agree with your body then call me trendy.
- February 11, 2011 at 7:10 AM
I can eat gluten/wheat for a couple of meals for one day only. If I continue eating it after that day my discomfort in the belly region becomes noticeable (bloating, upper ab pain). I have heard of the bloat and pain as "wheat belly"
Wheat carbs are the worst offenders for me and only by cutting them out does my ab pain and ab protrusion go away. My wife even noticed the ballooning of my belly the other day as I told her it felt like my skin was stretching. After three days of wheat/gluten free and eating only Protein, Fat, and Veggies, I feel relieved to say the least!
- February 11, 2011 at 7:11 AM
- Rich McCollum said...
My reactions upon reintroducing wheat-containing foods were identical to yours with a few additions. I did not experience anything major, but just felt bloated and gassy, and my eliminations were more often but in a smaller amount and not as quick/easy/clean.
I wouldn't say that I have a severe reaction to wheat, but I definitely feel better when I just stay away from it completely. Yes, I did notice a difference from "only" a home-made hamburger (quality beef) with the buns.
My conclusion: the reactions that I have, even though minor, are not balanced out by any added pleasure that wheat-containing items bring to a meal. So, I will continue to avoid it unless doing so would make a social situation overly awkward.
- February 11, 2011 at 7:18 AM
- Mike said...
I went gluten and sugar free for the month of January. The other morning I decided to go for Pancakes with real Maple Syrup... I expected to feel terrible, but I didn't really notice any adverse effects. Perhaps being insulin sensitive allowed for a smooth effect? Perhaps Crossfit workouts help? Anyway, I will remain sugar and flour free, because it is an easy way to avoid most baddies like cookies and brownies etc... But like you said, if I am a guest, I will enjoy what is served to me!
Oh! I also I ate a Pizza that night (I just thought I'd go crazy). I slept well, and actually digested it better than my meal the night before which was a grass fed steak salad!? I thought that was weird, any explanations?
- February 11, 2011 at 7:23 AM
- Bill Strahan said...
I did not do your experiment, but had a similar experience to yours. Gluten and all grain free for about 9 months, and then one night had a Guinness Extra Stout. ONE.
Slept poorly, felt almost like the flu, and woke up feeling very weird. I had trouble focusing my eyes, as weird as that sounds.
I made no association to the Guinness. I just figured I got exposed to some bug. Well, I still had 3 left in the refrigerator, and about 2 weeks later I had another, and had an identical response. Only then did I realize the correlation with the first Guinness.
With a tear in my eye, I gave the Guinness away. :) I only had 2-3 beers/year prior to that, so no big deal...but come on, it's Guinness after all!
- February 11, 2011 at 8:20 AM
I avoid wheat since I have Hashimoto's.
I've found that tiny amounts of wheat (wheat containing soy sauce rather than tamari) don't have any effect on me.
I cheated once in the past year, with a wheat flour croissant. It seemed to go right to my head, making me feel buzzed and emotionally unstable. I'm guessing it was just too much carb for me, compared to my usual LC diet.
I don't think it's the gluten that makes the difference, because within the same year I also accidentally ate a large plate of vegan meat believing it was real (this was GOOD stuff, seriously!) and experienced no negative reaction at all, besides wanting seconds.
In no case, whether involving wheat croissant, vegan meat, or years ago when I used to eat pasta and seitan on a regular basis, have I ever experienced digestive ailments after eating wheat!
And when I was in Europe, eating either bread or pasta every day, my only complaint was low blood pressure; I otherwise felt pretty good, lost some weight, and had no digestive difficulties of any kind, ever. Maybe my blood sugar was out of whack, I don't know, but I wasn't suffering.
So while I'm happy with my current grain-free diet, and think it's probably healthy in the long run, I just haven't sensibly experienced any positive results of avoiding wheat in particular.
- February 11, 2011 at 8:57 AM
- joanne said...
Very interesting posts on gluten. I find that I absolutely cannot eat store-bought bread, and sandwiches just make me feel blah. But I started grinding wheat at home and making my own whole wheat bread in a bread machine, and it is heavenly. I freeze the slices and eat them for breakfast every morning with a poached pastured egg and lots of butter. Yum!
I made a loaf of this fresh bread for a friend of mine and his partner, and they both commented that they felt great after eating it compared to regular wheat bread. (Which they were eating because it was "healthier" than white bread, but which neither of them liked.)
I'm with the other commenters who said that quality makes a big difference. This is not a scientifically based opinion, of course. :)
- February 11, 2011 at 9:12 AM
- David Belton said...
Perhaps negative gluten responses for some people takes longer to manifest and is more insidious than would present in the measurements you've taken?
- February 11, 2011 at 9:38 AM
- Aaron Blaisdell said...
"But I can go for weeks without eating a potato, a chicken thigh or broccoli, and all will digest just fine when I eat them again." This has been my experience as well. I haven't done a gluten-free challenge, but I try to avoid gluten to a strong degree. I have the same experience as you when it comes to beer. I stick to wine and spirits (mostly tequila and rum) nowadays. When I have a beer, I feel groggy and bloated the next morning--unless it's sorgham beer by St. Peters in which case I feel no different than if I had consumed wine or spirits. I can go months without eating kale, broccoli, duck, etc., and when I reintroduce it I have no noticeable problems. Beer and wheat, on the other hand, always brings back the bloat, gas, and grogginess.
- February 11, 2011 at 10:17 AM
I've been almost gluten-free for a while now, but 100% GF would mean not taking communion, and as that tiny bit doesn't seem to do anything horrible to me... it stays.
But at the end of January, I found myself unable to avoid eating a really lovely french baguette without being unpardonably rude, so... I did. And I could not wear my wedding ring for two days, because of the swelling.
- February 11, 2011 at 11:27 AM
- Jin said...
I've been gluten free for a couple years, since a stool test revealed elevated anti-gliadin antibodies. I'm not interested in doing a challenge because I feel so much better without gluten.
- February 11, 2011 at 1:43 PM
- terrence said...
Blogger Charlie said... "As I've said before, if you think you're gluten intolerant, see a psychologist."
Charlie, Charlie, Charlie, please stop projection your mental/emotional problems onto other people.
There is VAST amount of PROVEN scientific FACT that some people really are gluten intolerant.
Charlie, you make yourself look like an uninformed, ignorant fool when you spew your lack of knowledge – please stop doing. I am starting to feel really sorry for you, Charlie – and that is NOT a compliment on your mental problem.
- February 11, 2011 at 1:45 PM
- Acu-Greg said...
I actually had my gluten-free January last year in 2010. I included February, too. I wasn't super strict, so I'm sure that on occasion I got small amount of gluten from soy sauce, food additives, etc., but all the obvious sources were avoided. At the end of two months of avoidance, I had several slices of pizza for dinner one night. The next day I felt like I had been hit by a truck. I was groggy, sleepy, exhausted. So, I went back to being mostly gluten-free. I find I have fewer afternoon energy crashes, and my allergy to my girlfriend's cats almost vanished.
A few months later, I ordered a dish that came with farro. As I ate, I began to suspect that what I was eating might be barley or similar grain. I learned later that evening that farro generally refers to a whole grain wheat, usually an early form like spelt, emmer, or einkorn. The next day I felt as I did in February, only much worse. I was again exhausted, but this time I had a splitting headache, a queasy stomach, and no appetite. I didn't recover my energy for over three days.
- February 11, 2011 at 3:13 PM
I didn't sign up for your challenge as I have been totally grain free since last September with following a paleo diet (panu version). However, prior to completely eliminating grains, I was having a "cheat" meal of pizza about once a week. Each night after eating pizza (it took 3 times...I'm a slow learner), I would have fairly intense abdominal bloating and cramping lasting all night. More distressingly, I would also develop a pounding heart beat along with tachycardia and premature beats. I know the meats and cheeses weren't the problem, as I still eat those and I've never again experienced those symptoms again once I completely cut out all grains.
- February 11, 2011 at 4:21 PM
- Helen said...
(Part 1 of 2)
@ Charlie -
Gluten for some people has neurological effects, which might reverse your advice: if you are experiencing psychological problems, check your gluten.
Here are the titles on the first of six pages on PubMed of articles found under the search terms "gluten ataxia," a known medical disorder. This is just one neurological disorder that can be triggered by gluten.
(Ataxia: The loss of the ability to coordinate muscular movement, leading to unsteady movements and staggering walk.)
1. Selective loss of Purkinje cells in a patient with anti-gliadin-antibody-positive autoimmune cerebellar ataxia.
Nanri K, Shibuya M, Taguchi T, Hasegawa A, Tanaka N.
Diagn Pathol. 2011 Feb 4;6(1):14.
2. Gluten sensitivity: associated sporadic cerebellar ataxia in taiwan. Liu CS, Soong BW, Lee YC, Chen WL, Kuo CL, Cheng WL, Huang CS, Lin WT. Acta Neurol Taiwan. 2010 Dec;19(4):263-9.PMID: 21210327
3. [Clinical guidelines for the diagnosis and treatment of dermatitis herpetiformis].
Herrero-González JE.
Actas Dermosifiliogr. 2010 Dec;101(10):820-6. Spanish. PMID: 21159258
4. Serology of celiac disease in gluten-sensitive ataxia or neuropathy: role of deamidated gliadin antibody. Rashtak S, Rashtak S, Snyder MR, Pittock SJ, Wu TT, Gandhi MJ, Murray JA.
J Neuroimmunol. 2011 Jan;230(1-2):130-4. Epub 2010 Nov 6.PMID: 21056914
5. Sensory ganglionopathy due to gluten sensitivity.
Hadjivassiliou M, Rao DG, Wharton SB, Sanders DS, Grünewald RA, Davies-Jones AG.
Neurology. 2010 Sep 14;75(11):1003-8.PMID: 20837968 [PubMed - indexed for MEDLINE]Related citations
6. Positive serum antigliadin antibodies without celiac disease in the elderly population: does it matter? Ruuskanen A, Kaukinen K, Collin P, Huhtala H, Valve R, Mäki M, Luostarinen L. Scand J Gastroenterol. 2010 Oct;45(10):1197-202.
7. Cerebral Venous Sinus Thrombosis in 2 Children With Celiac Disease. Dogan M, Peker E, Akbayram S, Bektas MS, Basaranoglu M, Cesur Y, Caksen H.
Clin Appl Thromb Hemost. 2010 Jun 7.
8. GAD antibody-associated neurological illness and its relationship to gluten sensitivity.
Hadjivassiliou M, Aeschlimann D, Grünewald RA, Sanders DS, Sharrack B, Woodroofe N.
Acta Neurol Scand. 2011 Mar;123(3):175-80.
- February 12, 2011 at 7:24 AM
- Helen said...
(Part 2 of 2)
9. The neurology of coeliac disease in childhood: what is the evidence? A systematic review and meta-analysis. Lionetti E, Francavilla R, Pavone P, Pavone L, Francavilla T, Pulvirenti A, Giugno R, Ruggieri M.
Dev Med Child Neurol. 2010 Aug;52(8):700-7. Epub 2010 Mar 19. Review.PMID: 20345955 [PubMed - indexed for MEDLINE]Related citations
10. Gluten T cell epitope targeting by TG3 and TG6; implications for dermatitis herpetiformis and gluten ataxia.
Stamnaes J, Dorum S, Fleckenstein B, Aeschlimann D, Sollid LM.
Amino Acids. 2010 Nov;39(5):1183-91.
11. Anti transglutaminase antibodies cause ataxia in mice.
Boscolo S, Lorenzon A, Sblattero D, Florian F, Stebel M, Marzari R, Not T, Aeschlimann D, Ventura A, Hadjivassiliou M, Tongiorgi E.
PLoS One. 2010 Mar 15;5(3):e9698.
12. White matter lesions suggestive of amyotrophic lateral sclerosis attributed to celiac disease. Brown KJ, Jewells V, Herfarth H, Castillo M.
AJNR Am J Neuroradiol. 2010 May;31(5):880-1. Epub 2009 Nov 12.
13. Copper deficiency myeloneuropathy due to occult celiac disease. Goodman BP, Mistry DH, Pasha SF, Bosch PE.
Neurologist. 2009 Nov;15(6):355-6.
14. Neurological symptoms in patients with biopsy proven celiac disease. Bürk K, Farecki ML, Lamprecht G, Roth G, Decker P, Weller M, Rammensee HG, Oertel W.
Mov Disord. 2009 Dec 15;24(16):2358-62.
15. Immunological reactivity against neuronal and non-neuronal antigens in sporadic adult-onset cerebellar ataxia. Fancellu R, Pareyson D, Corsini E, Salsano E, Laurà M, Bernardi G, Antozzi C, Andreetta F, Colecchia M, Di Donato S, Mariotti C.
Eur Neurol. 2009;62(6):356-61. Epub 2009 Sep 26.
16. CD8(+)/perforin/granzyme B(+) effector cells infiltrating cerebellum and inferior olives in gluten ataxia. Mittelbronn M, Schittenhelm J, Bakos G, de Vos RA, Wehrmann M, Meyermann R, Bürk K. Neuropathology. 2010 Feb 1;30(1):92-6. Epub 2009 Jul 19.
17. Intravenous immunoglobulin therapy for autoantibody-positive cerebellar ataxia.
Nanri K, Okita M, Takeguchi M, Taguchi T, Ishiko T, Saito H, Otsuka T, Mitoma H, Koizumi K.
Intern Med. 2009;48(10):783-90. Epub 2009 May 15.
18. The gluten syndrome: a neurological disease.
Ford RP. Med Hypotheses. 2009 Sep;73(3):438-40. Epub 2009 Apr 29.PMID: 19406584 [PubMed - indexed for MEDLINE]Related citations
19. [A case of anti-gliadin-antibody-positive cerebellar ataxia effectively treated with intravenous immunoglobulin in which voxel-based morphometry and FineSRT were diagnostically useful]. Nanri K, Otsuka T, Takeguchi M, Taguchi T, Ishiko T, Mitoma H, Koizumi K.
Rinsho Shinkeigaku. 2009 Jan;49(1):37-42. Japanese.
20. Effect of intravenous immunoglobulin on cerebellar ataxia and neuropathic pain associated with celiac disease.
Souayah N, Chin RL, Brannagan TH, Latov N, Green PH, Kokoszka A, Sander HW. Eur J Neurol. 2008 Dec;15(12):1300-3.PMID:
- February 12, 2011 at 7:24 AM
- terrence said...
@Helen - you are wasting your time and pixels trying to inform and educate Charlie about gluten. He does not have the intelligence or, perhaps, the mental stabilize, to comprehend your very thoughtful and helpful comments.
I have come to think that "Charlie" or "Krishna" is nothing but a troll. He/she/it makes uninformed, stupid comments just to get reactions.
Notwithstanding "Charlie" thanks for the links.
- February 12, 2011 at 12:02 PM
- terrence said...
@Helen, Part 2
"Gluten for some people has neurological effects, which might reverse your advice: if you are experiencing psychological problems, check your gluten."
Indeed, Helen, indeed.
Charlie's rather obvious psychological problems may very well be the result of him ingesting gluten.
- February 12, 2011 at 12:06 PM
- Might-o'chondri-AL said...
- This comment has been removed by the author.
- February 12, 2011 at 2:40 PM
- Unknown said...
I am mostly gluten-free, but when I eat wheat my skin is a little more oily and I get a spot, that's all.
- February 12, 2011 at 3:44 PM
- Obee said...
I went on the Atkins diet about 15 years ago and suddenly all my allergies/asthma symptoms went away almost over night. After trial and error I discovered it was the wheat the gave me the problems. Other grains, like oats, did not. I have been wheat free, and allergy free since. I used to have to use two separate inhalers.
- February 13, 2011 at 5:36 AM
- Online earnings said...
very nice sharing keep it up....
- February 13, 2011 at 6:53 AM
- Nell said...
I've been gluten-free for nearly two years. I was struggling with chronic fatigue (now diagnosed with Lyme) and my stool test results were borderline. So I would be GF for a few weeks, then cave and eat some bread -- instantly worse fatigue, terrible mood, didn't want to be touched or talked to.
So I would go GF again. And fall off the wagon -- I was in France! the temptation was great! -- and all the bad symptoms would recur.
Finally I went GF for good, tested my family, all of whom have gluten sensitivity/possible celiac as well. We're all doing so much better without it. My son in particular does not get sick nearly as often and is much more cheerful, flexible, and energetic.
I used to adore bread, and crave it and overeat it. But now I hardly ever give it a thought. Being free of addiction is a good feeling.
- February 13, 2011 at 7:13 AM
- Summer said...
I would guess that the gas was probably related to the fructans in wheat. A lot of people have fructose intolerance and are bothered by both fructose and fructans. It may be totally unrelated to the gluten.
- February 13, 2011 at 9:44 AM
- Helen said...
One thing people should keep in mind when eliminating wheat is that it is a major source of betaine for Westerners, a relative of choline, which, as Stephan has pointed out, is essential to liver and brain function, and which most of us may be deficient in. Chris Masterjohn's post on choline is where I learned this:
Be sure you're getting enough betaine and choline from other sources, such as eggs and liver for choline, and spinach, quinoa, beets, an cauliflower for betaine. Among muscle meats, pork, especially bacon and ham, seems particularly high in choline.
I was wondering why my wheat elimination, though helping in some ways, seemed to coincide with a nosedive in my health in other ways. We don't have eggs in the house due to my daughter's severe egg allergy, and I share her trepidation around liver, unfortunately. I had no idea that eliminating wheat would put us in the danger zone, but now I think I have some tools to correct the problem.
Some others on gluten-free message boards report feeling more tired after going off wheat. Some of this could be gluten withdrawal, but maybe it's a betaine/choline deficiency.
BTW, a new idea I have for one reason (among many) that people who eat wheat tend to have poorer health outcomes is phosphate, which has been linked with accelerated aging in rodents and more cardiovascular events and kidney dysfunction in humans. It is a component of *baking soda* - essential for quick-breads, cookies, muffins, etc.
This means that gluten-free versions of those things should probably be eaten sparingly, since even if you're avoiding gluten reactions you're still getting that phosphate and/or aluminum, also found in some baking powders. Oh, and these goodies often have vegetable oils and or hydrogenated fats, too. And of course, as Jenny Ruhl (Diabetes Update/Blood Sugar 101) and Dr. David (Heart Scan Blog) assert, they are not a better alternative for anyone susceptible to blood glucose spikes from carbohydrates.
- February 13, 2011 at 10:23 AM
- terrence said...
Helen @ February 13, 2011 10:23 AM.
Thank you for posting this information. I have tried to get off wheat two or three times over the last year. I never make it and feel crappy and very tired most of the time.
I am trying it again, and feeling crappy. But I will now look into getting more choline and betaine. I will increase my egg intake; but I do not even like the smell of liver, so I will pass on it.
I will look into getting supplements of both choline and betaine.
Thanks, again.
- February 13, 2011 at 11:35 AM
- Unknown said...
I recently introduced some wheat in the form of bread after 8 months of no wheat. Honestly, I have to say, I love the sustained energy I got from it. One piece in the morning gave me enough energy for the entire day. I don't get this type of energy from any other carbohydrate. Instead I usually crash right after eating it (rice, potato, etc).
On the negative side, all the inflammatory issues I used to experience came back--overheat when sleeping, occasional shooting pains from the waist down, restless leg, mild congestion, ibs.
Any thoughts?
- February 13, 2011 at 12:04 PM
- Beulah said...
- This comment has been removed by the author.
- February 13, 2011 at 12:07 PM
- Helen said...
@ Terrence - Glad to share it.
Also wanted to correct my previous comment: by baking soda, I meant baking powder, and by Dr. David, I meant Dr. Davis. Eliminating wheat does not eliminate the need for proofreading, apparently.
- February 13, 2011 at 12:13 PM
- Might-o'chondri-AL said...
- This comment has been removed by the author.
- February 13, 2011 at 3:05 PM
- Helen said...
I may speak for many when I say, "Who ARE you, Might-o'chondri-AL?"
You have such a detailed knowledge of all sorts of bodily chemical reactions and their relationship to genetics, etc. Yet you remain a blogospheric mystery.
- February 13, 2011 at 3:38 PM
- Mindscaper said...
@Might-o-chondri Al
I too have wondered who you are and if you have a blog or web page of your own. I would surely follow it if you did. I'm very impressed by your detailed knowledge of molecular biology, nutrition, and metabolism. I always look forward to your comments.
- February 14, 2011 at 8:24 PM
- Mindscaper said...
- This comment has been removed by the author.
- February 14, 2011 at 8:38 PM
- Mindscaper said...
@ Might-o'chondri-Al
If after refraining from eating wheat for months its reintroduction disrupts gut biofilms could one use this as a way to wipe out the biofilm, cleanse, and then reintroduce good bacteria with pre/probiotics?
- February 14, 2011 at 8:43 PM
- Might-o'chondri-AL said...
- This comment has been removed by the author.
- February 16, 2011 at 11:34 AM
- Mindscaper said...
Thanks, AL. Your response was very helpful. I will look into Mannos a bit more. I regularly get homemade sauerkraut from the Dutch Market--might have to make some of my own fermented with kefir grains.
- February 16, 2011 at 12:30 PM
- Alice Y. said...
@Might-o'chondri-AL wrote "Probiotic specialty products don't seem to provide viable bacterial colonies in most individuals."
From an environmental microbiology perspective, last time I surveyed the literature (~5 yrs ago) I concluded that there was evidence that humans stabilize a particular mixture of gut bacteria by around normal weaning age (2-5 yrs). After that supplements will have only temporary effect - during their journey through the gut - but they may help to restocck number of gut bacteria if the individual's intestine already has a niche for those species. Some kinds of intestinal bacteria are very slow-growing, so populations may take 2yrs or so to recover numbers.
- February 20, 2011 at 2:12 AM
- Might-o'chondri-AL said...
- This comment has been removed by the author.
- February 20, 2011 at 11:58 AM
- AliceGreene said...
The major gas causing component in bread is YEAST, not wheat.
The major gas causing component in beer is ALCOHOL, not wheat.
If you want to test for wheat sensitivity, try a wheat product that does not contain either of these. Many people who think they are intolerant to wheat are really just reacting to yeast because their intestinal flora is out of balance.
Once you balance your intestinal flora you can again enjoy yeast breads and alcohol in moderation.
- February 21, 2011 at 1:19 PM
- Stephan Guyenet said...
Hi Alice,
Neither yeast nor alcohol (in moderation) give me gas.
- February 24, 2011 at 1:03 PM
- homebray said...
Late to the party, but I have been wheat free for nearly 2 years. People said I was crazy, but I knew I felt better. Then the patch of eczema that I have for 30+ years went away, they believe me now.
- March 6, 2011 at 9:07 PM
- janu said...
Me and my husband are on gluten free diet for the past 2 weeks and seeing great results. My husband is now able to burn 700 calories on tread as opposed to the 400 calories earlier when we often had wheat based foods. I feel more energized and active now. I always used to feel lethargic, anxious and depressed all the time. I guess I had been gluten intolerant from my childhood and the symptoms had been depression, difficulty in weight management, lethargy, anxiety, PCOS etc. But back in India especially those days nobody ever heard of the term gluten intolerance. Even today 99% people in India, don't know gluten intolerance exists. We are back to our traditional foods like idli,dosa,white rice etc and gave up chapatis, breads, cookies etc. My guess is we south indians are mostly gluten intolerant (i'm sure many would disagree), since wheat had never been our staple food until recent past. No gluten based food for that matter. The wheat based foods have become prevalent in south indian homes only for several decades. I also think wheat is not an obvious problem (at least symptomatically) for most of the north indians since they've been eating it for ages.
- February 25, 2012 at 11:46 AM


text:
Hello, I wish to explain issues with the game Crypto Age. I will also provide images which help to assist, I ask only that the Developers do NOT refresh this games data again, I and many others have spent money again on this game only for it to be reset or (non officially launched).
So with that said, there are a great deal of features that are missing from the game or messed up somehow upon launch.
| Missing Subordinate cities, there is no in city sub and there are zero subordinate cities on the map. There are meant to be subs as in the game there are multiple items and dialogues that appear that explain sub cities and similar relations.
| No Generals. The tavern in the game is broken, its missing multiple options such as Recruit and Wheel of fortune. Although there are multiple buttons in different areas that say recruit here... link you to the tavern, but only to find the tavern options missing.
| The black market is missing the market, this option is again supposed to be in the game as many dialogues and options direct us to the market thats not there.
| Culture: The ability to change your culture is doable, but only upon creating the account. Other than this, the option is not shown anywhere else.
| General Gear and Monarch Gear: The entire Monarch Gear page on the Players Profile is missing, we do not have this. We are supposed to have this as its clear in the players stats that Monarch Gear is a stat.
| The buyable bounty cave is unclickable. Its just a non working feature.
| Event/ Promotional packs are unbuyable. The events are a big issue in the game, currently not working. No special bosses, no special rewards. Lucky cards also do not get dropped ever. There is no option to buy special packs either.
| Invite friends is a feature thats also missing from the game, no sign of it anywhere. This feature was really good and I wish for it be in the game.
| The entire WON system, buyable WON tokens is broken and non working, again another money feature that is flawed and needs resolving.
| One of the most important issues currently... is Facebook Login integration not currently working. The only way a player can save their account is via Game Centre. Even the email login system is flawed. Please integrate Facebook logins.
| Undead invasion is broken. Currently if any alliance in the entire server opens their Undead... the entire world map is broken for every Crypto Age player. The world map is unusable, its a consistent WiFi symbol, and this lasts 48 hours for everyone from when the player opens the Undead.
| Daily rewards, gems and speeds. I played Evony Kings Return for 2 years and can happily say that the rewards on Crypto Age are practically at a 0 on a scale out of 10 and needs to be improved.
| The fact the game IS available on the google play store to be downloaded, however, its not playable or loadable and the excuse is that its not released on the play store. However its on the play store and currently free to download. Please activate the servers on the google play store so we can play on Android devices.
So again, please to the moderators that read this from Crypto Age... You currently have 40 Active players on your app, and presumably only 15 to 20 have spent money. This can all be changed, bu you must integrate the above features, fix them if theyre simply broken or add if not. And also to release the game fully on the play store so that your active users can quadruple. And fix your areas where purchases are usable, such as weekly promo events, the bounty cave and your WON system. The WON wallet isnt even accessible.
But please.... do NOT restart games, accounts, or players purchases. Simply push an update with the improvements and fixes so that we do not need to charge back and never return to the game. We just simply want you to update it. Thank you again for reading, please pass on to Crypto Age developers.
Crypto Age name: Kaution
Crypto Age ID: 97


text:
Jonathan Pantaleon, one of the most versatile, talented and respected artists in the airbrush industry, will introduce new projects and amazing techniques at the LAS VEGAS AIRBRUSH GETAWAY, OCT 6-10 at the NEW Tropicana Hotel. For more information on the intensive MURALS ON STEEL class, or the 20 other ALL HANDS-ON COURSES, call 800-876-2472 or 732-233-7878, or click on "Las Vegas Airbrush Getaway" above.
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Createx: http://www.createxcolors.com/
FBS Tape: http://www.fbs-online.com/


text:
Not a big fan of 3711. The mouthfeel is a bit too slick for my palate. I prefer WLP565, 566.
I don't have any experience with any Saison yeasts so anything will be a good starting point I suppose. Is 565 the one that takes a while to finish and seems to stop after a couple of days?


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First on, last off - The 24H Foundation
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Benzoin Resin (Styrax benzoin).
Magical Uses: Purification and when burnt with bay leaves or basil aids a successful business.
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text:
CHICAGO, IL (AP) — The nation's largest doctors' group says about one in five payments of medical claims by commercial health insurers is inaccurate, shortchanging physicians.
The American Medical Association released its annual report card on insurers Monday. The AMA says eliminating mistakes would save doctors and insurers $17 billion a year.
The AMA rated UnitedHealthcare highest of seven commercial insurers with an accuracy rate of 90 percent.
Medicare, the government program for people 65 and older, was even better, with a 96 percent accuracy rate.
Lowest rated was Anthem Blue Cross with 61 percent. Anthem's parent company, WellPoint Inc., responded that it is increasing electronic claims processing while decreasing paper billing and now receives about nine of 10 claims electronically.
The AMA is holding its annual meeting in Chicago.
Online: http://www.ama-assn.org/go/reportcard
(Copyright 2011 by The Associated Press. All Rights Reserved.)


text:
Caring for Your PSP
- Most Important: Don't Break It
- Keep Your PSP Clean
- Care for PSP Media and Headphones
It's solid. It's heavy. It's built to last.
Even so, your PSP is not a brick. You can easily turn it into one, however, by failing to treat it with care. It's a little too big to be a paperweight, but it would make a fantastic doorstop, as you'd expect at its high price. If you want a doorstop, go to the hardware store and buy one. If you want your PSP to work as a PSP, treat it with respect.
Things that you use with your PSP also need a little bit of TLC. Those Memory Stick Duos are solid-state, nonvolatile masterworks of flash memory, but they're still delicate. Your Universal Media Discs (UMDs), the sources of delightful movies and games, are valuable and vulnerable. Even the earphones and their little wired remote are subject to destruction, and not merely by vandals with scissors. (True story: A friend of mine works in an office under a draconian supervisor who hates MP3 players and the like. On occasions in which a worker doesn't hear something important because of the earbuds in her ears, the boss will sneak up with a pair of scissors and snip the headphone wire. (I wonder how he would deal with a set of Bluetooth wireless headphones?)
Most Important: Don't Break It
Because you own a PSP, you probably have several other electronic devices: a digital camera, an MP3 player, a notebook PC, a USB can opener, or what have you. You probably already know that such devices need to be treated with care. You don't throw them. You try not to drop them. You don't bury them. You don't use them as bases in pickup games of Wiffle Ball.
Just as those thingies need extra-special care beyond the level of attention you'd bestow upon, say, a Garden Weasel, your PSP has its own issues with abuse. And if you break it through your own failure to respect its vulnerabilities, you'll probably void the warranty, where-upon—lo and behold—there's your attractive and expensive doorstop.
The Obligatory Lists of Dos and Don'ts
That's right: Here come the lists! I think it's more interesting and pleasing to the eye to present sexy, bulleted lists than boring, blocky paragraphs, so here we go.
- ... drop it. That seems like common sense, but I hope this advice will stay with you should you, say, get drunk and decide to impress your friends by juggling expensive stuff.
- ... get it wet. This isn't as clear-cut as it seems. Most people who douse their electronics do so in ways they didn't intend; obviously, they refrain from hurling a PSP into the Erie Canal, but they absently set a tasty energy drink on the coffee table, spill it, and discover their PSP in a sticky puddle on the table.
- ... keep the PSP in a moist environment. Humidity isn't good for electronics, and condensation can form on the circuitry inside the PSP.
- ... leave the PSP in direct sunlight. That can damage the electronic components (aka the guts), shorten the life of the battery, and harm the Memory Stick Duo.
- ... abuse the UMD door. This door is one of the most fragile parts of the PSP, and if it breaks, there's no good way to fix it except to have someone at an authorized repair shop fix it. That can be expensive.
- ... get crumbs or excessive amounts of dust on your PSP. Try not to play while eating or just after eating without washing your hands. Little particles can fall into the button switches and gum up the works.
- ... be gentle with the controls. Refrain from jamming the buttons with all your might and wrenching the analog controller for all you're worth. The buttons have two states: down and up. When you've pressed a button far enough down for it to register, pressing it harder won't offer any advantage—but will wear down the switch that the button activates.
- ... store your PSP in a dry area that's above freezing but below 80 degrees F or so.
- ... charge the PSP battery on a regular basis. There's no need to let it drain completely; it's not a NiCad battery with memory issues.
- ... clean the PSP on a regular basis (see "Keep Your PSP Clean" later in this chapter).
- ... avoid static. Don't keep your PSP on a carpeted floor or in front of a tube-type television set. Static electricity can fry components.
- ... turn off the PSP when you're not using it. Don't leave it on stand-by too long unless you have an unsaved game that you simply have to put down. Turning it off refreshes the memory and clears the various caches, which is good.
- ... use the wrist strap that came with the PSP. That way, you're less likely to drop it.
Them's the basics. The PSP is a portable device, of course, as its very moniker says. That opens a whole new area of care, so I'll give it its own section.
Safe Traveling with Your PSP
There, that's better. Whether you want to take your PSP for a walk to the park or around the world in a hot-air balloon, all Jules Verne–like, you need to take some precautions to ensure its safe arrival at your destination.
Instead of assaulting you with another list of dos and don'ts, I'm simply going to give you suggestions—very strong suggestions—in a friendly bulleted-list format. Here it is:
- Use the pouch! Your PSP came with a padded pouch for carrying it about. Whether you pack it in a suitcase or carry it in your pocket, put it in its pouch when you're not using it. You can even roll up the PSP's earphones and remote and then tuck them into the pouch too.
- Refrain from taking your PSP into hostile environments. By that, I don't mean combat zones (although you should avoid them); I mean environments hostile to electronics. Keep the PSP away from beaches and pools, for example, as moisture, sand, and salt spray can have a negative impact on its functionality. Don't play with it in the steam room. Don't expose it to rain.
- If you pack it in a bag, be careful. Don't allow it to be crushed beneath other stuff. If you have to pack a PSP in a suitcase, I suggest packing it between layers of soft clothing.
- If you carry it in your pocket, make sure that it won't fall out. Also, if you carry it in a back pocket, don't forget about it and sit on it.
- I suggest that you don't play with a PSP over hard surfaces like pavement or ceramic tile, just in case you drop it. Play over grass, carpet, and such. Better still, play sitting down, so that if you do drop your PSP, it lands in your nice soft lap.
- Although you certainly can go jogging with a PSP, I suggest that you don't. I know, I know—unlike some PDAs and MP3 players, it lacks a hard drive, using solid-state Memory Stick Duos instead. Because the PSP does have quite a few moving parts, however, I don't recommend bouncing it around all that much. Besides, some studies show that a brisk, low-impact walk is actually better for your body than a jog. Just sayin'.
- Don't forget the charger if you go on a trip. Leaving the battery stone dead for a long time isn't good. Get a carrying bag in which you can keep the PSP, headphones, charger, and some UMDs, and make a habit of storing the charger in there when you're not using it.
- This may seem like common sense, but don't use your PSP during weddings, funerals, college lectures, and other places where you're supposed to be paying attention. It's rude.
- Turn off the WLAN switch when you're not networked, either as part of an ad-hoc or an infrastructure network. You'll extend battery life. Also, if by chance other people near you have PSPs and want to play via WLAN, your PSP won't interfere.


text:
Britons believe broadband connectivity to be the product that has most changed their lives over the past ten years.
So says a survey of 2243 adults "weighted to represent UK population" carried out by a marketing consultancy you've never heard of on behalf of a management consultancy you've also never heard of.
Punters placed home broadband at the top of the chart, scoring it 192 points out of 300, a rating that places the service well ahead of second-placed entry, online shopping, which garnered 94 points.
Google alone took third place, scoring 54 points.
Other such significant contributors to Britons' wellbeing include chip'n'pin, digital cameras, online comparison sites, community recycling, health-centric food labels and low-cost air travel.
Most folk favoured services that saved them time or money, they indicated, rather than rate products for their technology alone. But they generally rated usefulness above all, so it's not at all surprising that fast, always-on internet access scored so highly.
The decade's most disliked "innovations" proved to be reality TV - odd, given how many Brits watch the wretched stuff - closely followed by Facebook, pop-up advertising, Twitter, automated phone systems, congestion charging and plastic bags you have to pay for.
Rounding out the list were some bizarre entries: DVD subscription services, tracker mortgages and public bike schemes, all of which while one might not care to use surely don't warrant actual hatred.
Bad luck, Boris. ®


text:
YAM - Yet Another Mailer (#2) - Bad RCPT command response (#50) - Message List
Help! All of a sudden I can't send emails from neither YAM, nor AEmail. I can recieve email and surf the internet with no problem, and I can strangely enough even send emails from Voyager's internal email program, but not from YAM or AEmail. It has been that way since Sunday, and I don't remember changing anytging on my computer during the weekend. It has otherwise been working fine for years. My provider says the server works fine, so it can't be their fault.
When activating the debug option in YAM and attempting to send an email to myself, I got this (I have munged the addresses for spam protection)…
SERVER[0030]: 220 pfepb.post.tele.dk ESMTP CLIENT[0019]: HELO post.tele.dk SERVER[0024]: 250 pfepb.post.tele.dk CLIENT[0036]: MAIL FROM:<email@example.com> SERVER[0008]: 250 Ok CLIENT[0027]: RCPT TO:<email@example.com> SERVER[0058]: 550 <post.tele.dk>: Helo command rejected: Access denied CLIENT[0006]: RSET SERVER[0008]: 250 Ok Bad RCPT command response: 550 <post.tele.dk>: Helo command rejected: Access denied The mail server couldn't execute the command and replied with the error message.
Does anyone have the tiniest clue what could cause this problem?
Message #244
I have solved my problem. My provider finally admitted it was their fault, and came up with a solution.AllanMar 9, 2005, 4:22:25 PM (16 years ago)
Message #245
What did your provider do? I can download all day, but I can't send mail and I get that same bad RCPT command response:
The mail server couldn't execute the command and replied with the error message.
So what's the solution :NorrinRaddSep 18, 2005, 2:54:33 AM (15 years ago)