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"Bookworm" printable planner page (above) by Syndee Rogers-Nuckles includes the following products:
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Skin discoloration
Skin discoloration can be caused by a whole lot of different things, including contact dermatitis, burns, cold or hot temperatures, blushing, exercise, and dryness. For the most part, it's usually nothing to worry about! Sometimes, though, your skin can change color because of an autoimmune disease (like lupus), hormone fluctuations (due to pregnancy or Addison's disease), taking too many of certain supplements, liver problems, or skin cancer. If you have an autoimmune condition like lupus, you're likely to become very sensitive to the sun's ultraviolet rays, so make sure you lather up with SPF whenever you go outdoors, no matter the season (actually, this advice goes for every single one of us!). Treatment for skin conditions that cause discoloration depends a lot on the specific diagnosis, but you can try topical salves or discuss other options, such as steroid creams, with your practitioner. Some research has supported essential oils, such as lavender and geranium, as natural methods to treat skin flare-ups. If you've worked with your practitioner and determined that the discoloration doesn't signal something more serious, try not to stress too much about it! Skin isn't supposed to look like airbrushed perfection, and it doesn't have to appear flawless to be healthy.
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- Lupus Foundation of America. How lupus affects the skin. Lupus Foundation of America. How lupus affects the skin.
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- American Academy of Dermatology. Eczema/dermatitis. American Academy of Dermatology. Eczema/dermatitis.
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- Cleveland Clinic. Pigmentation: Abnormal pigmentation. Cleveland Clinic. Pigmentation: Abnormal pigmentation.


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Silver Lesson Package
3 x 1 hour or (6 x 30 mins) golf lessons with Chris Fletcher Senior PGA Golf Professional & £30 ball credit to use at Trafford Golf Centre.
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Dark chocolate, covered in a beautiful array of autumn colored foil. Perfect for a candy dish, as an accent on your Thanksgiving table, or to share with friends.
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(216) 932-3200
Mon – Thurs: 10am – 8pm
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By The Nation
Arnon announced his incarceration by posting "I have been arrested" on social media.
He is one of the five anti-government protesters slapped with charges of violating the emergency decree by holding an assembly of more than five persons in a protest outside the Army headquarters on July 20.
On August 3, Anon also delivered a public speech on the role of the monarchy, saying it should be debated openly in order to avoid the risk of future violence between opposing political camps.
Thai netizens have been tweeting and retweeting announcement of Arnon's arrest under the #FreeArnon hashtag in a move to pressure the authorities into releasing the activists.
The arrest warrants for protest leaders were issued after Vice Minister of the Office of the Prime Minister Apiwat Kantong complained that speeches delivered at the Harry Potter-themed protest on August 3 undermined the monarchy.
The five were also being summoned for gathering outside the Army headquarters.
Other activists facing arrest are Panupong Jadnok and Parit Chiwarak, though the latter is contacting a lawyer to ask if he should give himself up to police.


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Jamie graduated in 2014 and works for an advertising company called 'Maverick Advertising and Design' as a Digital Asset Manager/Assistant Editor.
What do you think is the most valuable piece of information or learning that you received at Solent?
I think the most important thing I gained from Solent was contacts with industry professionals. For example, when they ran the Solent Post day last year I managed to gain contacts with the editors that came along that day. However, the most important thing I learnt was when I did the Avid Certification Course because this enabled me to get the job I am doing at the moment, it's very widely used in the industry.
If you could give your undergraduate self a helpful piece of advice, what would it be?
Take every opportunity that comes your way because you never know when the next one will come along. I did 4 months or so of doing various work experience and then had about 6 months without any and it's hard to get back on the horse.
What is your proudest moment?
The best project I have worked on at Solent was when I worked as an edit trainee for a Channel 4 drama called 'Utopia'. At Solent I became associated with a company called 'Jack in the Box Films' where I worked on a variety of projects including a 20 min drama and a 5 minute film, shot on a 4K RED EPIC camera and I got to learn the workflow for that
Where do you want to be/where do you see yourself in 5 years time?
I would like to be working in broadcast TV as an assistant editor, hopefully on a high end drama but I'm aiming high there.
Interviewed October 2014


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Languedoc Roussillon
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8 Items
per page
- Mont Rocher 2017 Viognier Vieilles VignesIn stockDelicious peach and apricot scented Viognier with a little hint of spice and spring flowers Learn More
- Domaine de Bertier 2018 Merlot/CabernetIn stockPhilippe de Bertier makes excellent value reds from his domaine near Beziers. This blend of the two Bordeaux varieties... Learn More
- Domaine de Bertier 2019 Sauvignon/ViognierIn stockA blend of two aromartic varieties which captures the essence of each. The green and yellow fruits of the Sauvignon... Learn More
- Calmel & Joseph 2018 Malbec 'Villa Blanche'In stock£10.99 As low as £10.11Great value Malbec from Languedoc which has the rich black fruits of this variety of blueberry, blackberry and black... Learn More
- Chateau Fontareche 2018 Corbieres Vieilles VignesIn stock£10.99 As low as £10.11Lovely deep colour with a Clarety nose. Rich and spicy with scents of black cherries. Soft and plump with silky... Learn More
- Calmel & Joseph 2018 Viognier 'Villa Blanche'In stock£11.99 As low as £11.03Quite a full style of Viognier which shows the typical stoned fruit and honeysuckle notes of the variety, with added... Learn More
- Calmel & Joseph 2017 St ChinianIn stock£12.99 As low as £11.95From the black schist soils of St Chinian, this is a brooding, masculine wine, but on the palate it is lifted with... Learn More
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8 Items
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Key School Updates
Announcements for the Week of 6/1
Resources for talking to your children about Racism
And below is a reading of 'Let's Talk about Race' by Julius Lester
Let's Talk About Race by Julius Lester
Meal Distribution at Key School and Veggies every Tuesday!
SEAMAAC continues to hold distributions of bagged meals in front of Key School every Monday-Friday from 11:30 -1 PM. EVERY TUESDAY a box of fresh produce will be distributed in addition to meals.
No identification is required. All individuals will receive 1 bag which contains 2 meals. Safety precautions will be in place.
Phishing Scam Warning
We wanted to make you aware that there might be scams circulating on Whatsapp offering grocery vouchers or food boxes. These and other similar texts you may have received are not true - please do not click on these or give out personal information to any untrustworthy website.
Upcoming Virtual Meetings!
Are you a new parent?
Check out these resources below for how to receive free baby food, diapers, crib, and other support during Covid-19
PCCY's Child Helpline helps families get health insurance for FREE and in every language!
The Helpline is for parents:
- Who have lost their jobs and are worried about losing health coverage for their children and themselves
- Are concerned with the costs of testing and treatment of COVID-19
- With any questions about CHIP or Medicaid coverage
- With language interpretation needs
Call the Helpline at 215-563-5848 x 17
Meals for Children Pickup
Thursday, June 4th, 9-11am
2101 South Broad Street
Philadelphia, PA
South Philadelphia High School (2101 S. Broad St) and Furness High School (1900 S. 3rd St) are both distributing Free Meals for families. Parents will be able to pick up a box of five breakfast meals, five lunch meals and a half gallon of milk for EACH student in the family.
Free Box of Food
Thursday, June 4th, 10am-12pm
300 West Shunk Street
Philadelphia, PA
Every MONDAY and THURSDAY you can visit Murphy Rec Center to receive a box of free food. This is for anyone who lives in Philadelphia and needs food.
- Sites are open Mondays and Thursdays from 10 a.m. - 12 p.m.
- Residents can pick up one box per household. Supplies will last up to five days.
- Residents do not need to present an ID or proof of income for eligibility.
- Mondays will be dried and canned goods,Thursdays will feature produce
Here is the link to the full list of food sites: https://www.phila.gov/2020-03-28-where-to-find-free-nutritious-food-during-covid-19/
Please fill out the parent survey!
The School District of Philadelphia is still asking parents fill out the yearly parent survey. The link is below for all parents or caregivers to fill out. You will need your child's student ID number (this is their lunch number).This is secure and anonymous. Choose your language at the top of the page if you need help with translation.
Parent Survey
The survey is designed to find out what you think about your child's school. We encourage you to take the survey for each of your children! The District-wide Parent & Guardian Survey is open to parents and guardians of students in Philadelphia public and Charter schools.


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Fully furnished, recently renovated, 2 bed, 1 bath ground floor apartment with lounge/diner, open plan kitchen and good size front and rear patios on sought after residential complex with pool, located close to all amenities and the sea front. Extras include security grills and storeroom.
2 bed apartment for sale in Sand Club, Golf del Sur
2 1 The property was added on 6/23/2020 1:33:49 PM.FormatDate()
Property details
Sand Club, Golf del Sur, Tenerife
EPC: Pending
Ref: SC125
2 bedrooms
1 bathroom
First listed on
Ref: SC125 Approx. £145,656
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Contact Tenerife Prime Property
About the area
About Tenerife Prime Property
Contact details
- 922 703 725
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- [email protected]
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Infosys Announces Results for the Quarter ended December 31, 2012
Q3 Revenues grow by 5.7% quarter on quarter
Bangalore, India – January 11, 2013
- Revenues grow by 12.1% year on year
- The company won 8 large outsourcing deals amounting to US$ 731 million of total contract value
- 14 new wins for Infosys' products and platforms
- Infosys and its subsidiaries added 53 clients during the quarter
- Gross addition of 7,499 employees (net addition of 977) for the quarter by Infosys and its subsidiaries.
- 1,55,629 employees as on December 31, 2012 for Infosys and its subsidiaries
- Completed the acquisition of Lodestone Holding AG, a leading management consultancy based in Switzerland
- Infosys American Depositary Shares (ADS) have started trading on the New York Stock Exchange (NYSE) under the ticker symbol 'INFY'. The company is in the process of listing its ADS on the Paris and London exchanges of NYSE Euronext.


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Epson printers and ink question
Page 1 of 1
Epson printers and ink question
I am looking into buying an Epson printer with the fallible ink wells. However, some places sell a printer that uses a 500 series ink and others use a 600 series ink. WalMart today had a 500 series printer but only 600 series ink bottles. My question: Can you use 500 series ink in a 600 printer and vice versa, 600 ink in a 500 printer. The ink all comes in the same color bottles
- Share Holder
- Posts : 1005
Join date : 2012-06-27
Re: Epson printers and ink question
don't know the answer but 500 series ink is at Costco, Mercado Libre Mexico and probably Amazon mx. I have an Epson L5190 that uses it.
- Share Holder
- Posts : 747
Join date : 2010-04-05
Location : Cottonwood, Arizona
Humor : A little English
Re: Epson printers and ink question
I'd never buy a fallible printer - who needs more mistakes! OTOH, I have a fillable one I love. 500 series.
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Thank you to your conversations that are comfortable. Thank you for sharing your love and needing to make me yours. No matter how at what distance or slowly our courtship grows, I understand standing before our family and God, vowing to be your partner for life, was the choice I could have ever made. Each day that passes will make our love to each other grow stronger. Our desires will continue to extend across any space, over every mountain and ocean between 29, although I know that it's difficult for us to be apart Plus. Nothing can stand between us, and nothing will Highgate SK me from meeting you.
Adhere to up You never recognize when either of one has to leave suddenly. Consider a situation where you find someone you get in touch with, everything seems to be taking place well, until her friends drag her away as well as you don't have the possibility to ask her for her telephone number! Consequently, it is necessary that you find something usual beforehand and also you can utilize it later. There are a pair of basic means in which you can do this. If you are both thinking about the same sort of songs, then you can welcome her to a performance or a performance. If you have any common interests, after that you can ask her if she could intend to talk concerning it for some time longer. If you both appreciate a certain cuisine, then you can inform her regarding a great restaurant as well as ask her if she wants to pursue a dish with you. Take the effort Many females tend to such as a male who is decisive and can take an effort. So, whenever you attempt to arrange a day, don't ask her to choose the place and also never waver. You must always have a couple of bars or restaurants that are optimal for a day as well as you can take her to among those places. It is quite reliable if you take her to a place in community that offers the most effective tacos instead of asking her if she may wish to go with Mexican food.
Shortly, my other buddies caught on to the entire" Stix" nickname, and at one point, a blunt buddy of mine handed me a note local sluts what exactly I found so appealing about this junior. I didn't possess any real explanation for this, so I simply passed her back a notice that said, " Stix lights my fire. " The next time I watched it, and I expect he never figured out since I had autographed that note that was his nickname, it was putting by his locker.
If you receive a message out of a man and he turns out to be a real moron, just say something like, " I'm sorry, I don't believe this may work out after all" , or something similar. Of course, you could just ignore or block him.
I went to one of the Vegas gigs, but it was among his chesp local sluts Sydney Inlet. Icouldn't Highgate Saskatchewan local ammature sluts to notice there was this selfishness about him. He'd begin walking through the casino and also leave me yards behind him. If he would like to walk off, that is fine, I am in Vegas! " He believed. Making music and screwing little groupie women for so long that he had no clue how to take care of had so absorbed his mind. We did a couple of things around the city together, and it was time for me to go home. I understood the space was not anything I had been interested in, although I was beginning to like him.
Again, it's a local sluts exposed Valley Centre SK game. So it is absolutely imperative that you do not get hooked on infatuation's medication. For whatever reason, if this interaction goes sour, you are going to feel rejected, that will likely cause depression if for example, someone does not like you.
Notice: the girl was cried by him. She won, but she did not understand. It is" away" rather than" of. " They were having a normal naughty conversation and across the line, the man introduced to iLast Game, but she did not know how to play it, so he taught her. She became hooked on the game.
Another approach to secure a date on social networking sites would be to become involved with a few. In the time of hubby and fuck buddy Highgate the most addictive game is Chocolate Crush Saga and from what I know one another is approached by people on Facebook asking resides' or advice whenever they get stuck on a level. This could be your way in to talking to someone you find interesting. I asked her how this came about( because I do not know how this website functions) and she explained that whilst playing scrabble together they were having conversations with the instant messaging purpose where they discovered more about each other subsequently arranged a Highgate SK local sluts lookinf for a fuck from that point. I'm personally not a fan of instant messaging since I have no time to sit around on a computer talking to someone( or playing games for that matter) but ifyou're already on one of these sites playing a game then having a conversation with the individual you are playing with or against retains distinct possibilities.
Recall: show, do not tell. Instead of saying" I enjoy exotic food" , declare your enthusiasm for authentic Eritrean cuisine. Rather than saying" I enjoy the outside" and" Making a Highgate SK sexy local amateur sluts in panties tree was fun" , relate a story of your perfect day on a wooded mountain road overlooking the historic mining town that once was home to your grandmother's father. Accentuate your own uniqueness! Take that list of information about yourself and change each one into one descriptive sentence. Now group those sentences together into descriptive topics like personality, interests, goals, things that make you happy, profession, family, etc. . Now tweak your sentences so everything sound like it fits together. A trick I use is to read it aloud to make sure it seems right.
. . Highgate SK local sluts looking for a fuck! I must have played Pantera or something else I. But I didn't wish to follow whatever I loathed. The mood in the car was poor enough. We'd been driving for an hour and the only words which had passed between us were, " I need to visit the toilet. " So I could use the amenities, dom had pulled to a service station. I got back to the car and hoped that I wouldn't be turned by the drive against Frank Ocean.
Successful results is correct thinking, decisions made by reaping preceding actions that turned out nicely Before Highgate SK korean prostitutes thinking can happen, the firs secret is to produce a shift is to increase your awareness of your customs self talk, inner discussion; . You can't change anything unless you understand about it first.
The most usual are profiles made to make you click some sort of link. After you match together Normally they use the same copied and pasted messages. Here's a standard recent one going around on Tinder: These templates change from time to time, but as a general rule, anything using a hyperlink from the first two or message with any message that didn't fit with the conversation is just an automated spam bot.
When you register for an account email providers request safety questions. This is to help identify you in the event. Other institutions, credit card accounts and your bank local sluts also do this. Like your passwords, get their replies, and the safety questions that you opt for. The best thing in case you have the choice, is to produce your own security question- - one that only you understand and to which only you know the solution.
But we need to clarify, what does your heart want, as I did in my own journey? Cupid brings back, and flourish, arrow right to the heart! If it had been easy right? In love, the sky's the sugar babies are prostitutes, or can it be? What are the beliefs about love? What are your feelings? I am going to ask you a couple of questions, and I want you to consider these as you about online dating Highgate on reading? Why is finding someone so important? What should you bring to the table for two? Are you ready to be adored the way that you need to be loved? A recurrent theme in my novel is" equally yoked ain't a joke. " My passion is words, and many rose city hookers I love to wander down the path of others bring to the table. This quotation is unquestionably a place, right time kinda quote, it is from where, or by Pablo Neruda: I love you without knowing how, or when.
Another humiliation was going to begin: Trigger system began to work. I had no idea that the horse needed to visit the bathroom until I suddenly heard a phtt, phtt, phtt emanating from his region in time into the pace that is trotting we were around. Oh, man! I expected no one thought those sounds were coming from me! His jules millenium prostitutes along with trigger lasted the whole time we trotted.


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The Ideal Practice Space – Making The Most Out Of Your Rehearsal Space
In our last blog we went over how to get the most out of a short practice, so we thought we'd say a few words on where to practice – the ideal practice space. If you haven't already gathered, more practice = better musician. Not only more practice, but quality practice. Setting up a good space can make all the difference, as we shall see..
So, which room to practice in? Well, as you'd expect for anything involving concentration, a room free of distractions. Yeah right, you say, no room in our house is free from distractions – maybe the piano is in the lounge room and so is the TV, maybe younger siblings are everywhere. Setting up a room similar to when you see your guitar teacher is ideal.
Do your best.
Turn the TV off, or practice in the morning, if siblings can't be lured away somehow, get them involved? Clap the beat? Sing along? Certainly remove phone, tablets, laptops etc, unless they're exclusively being used in practice.
Can't I practice in front of the TV, idly picking at my guitar? Sure you can, after actual practice.
All fairly obvious suggestions, but 10 minutes uninterrupted can do wonders!
Don't go to the other extreme and ostracise your budding musician to a freezing, dark corner of the house or in the basement. The room should be comfortable, well lit, and preferably somewhat inspiring. Think about the lighting.
Natural light is great, but if not, a nice warm light/lamp is preferable to a blaring, buzzing fluro. This might seem trivial, but lighting has a profound affect on our mood and our ability to concentrate. This is especially the case if practice involves performing a piece with feeling, or attempting a composition.
As far as inspiration goes, a few posters in the practice space of their (current?) favourite artist can be a great motivator. Speaking of essentials for the practice space, let's move from the where to the what..
I'll just go ahead and rattle off the items that every student should have, with (sort of) the important stuff at the top.
Music stand – piano students are ok, but virtually everyone else needs a stand. Well why can't I just use the table, I hear you say. Because if you do, soon enough your neck will get sore and you're done. Get a stand! They're cheap (look online).
As in your music lessons, it should be set up at eye height, even if you like to practise standing up. Some stands don't have those page-holding springy things, so if that's you, a few clothes pegs can help keep the book open.
Metronome – yes they're not very interesting, musically speaking, but they can work wonders with timing and rhythm. Don't use them all the time, but they're great for scales, sight-reading and new pieces. You can still get the analogue ones, but there are also loads of apps, including fun metronomes, such as this.
A comfortable seat – for piano students a bench at the correct height is ideal. An uncomfortable seat can cause back pain. Not good. Make sure the seat allows for the correct posture for playing your instrument. The smaller people might need a footstool.. Check with teacher.
Tuner – MUST HAVE guitar students! You'll learn to tune by ear one day, but for everybody's sakes use a tuner to start with! What's more, if your guitar sounds bad you'll probably attribute it to your playing, and start telling yourself how you were never meant to be a musician etc etc. Of course with singers, especially newbie singers who've not fully learnt how to pitch their voice, in the absence of your singing teacher or a piano/instrument, you can use it to check your pitch.
Clip on tuners are great as they're always there on the guitar, ready to save the day. If not there are plenty of free apps, like this
Notepad, pencils etc. – Notepad for writing out a 'practice plan' for the day or week. Also, if you think of something you need to do, write it down and keep practising. Don't get up, check calendar, phone etc. Do that later.
Instrument stand – can the make the whole thing more painless if you need to keep checking manuscripts or taking notes.
What else?
Make practising your instrument easy, whether it's vocal training, guitar shredding or sitting at the keys.. If you can leave it all set up, great! If not, consider leaving the piano lid open so everyone can tinkle with it throughout the day; leave the guitar out of its case (if safe from toddlers!), and preferably in the living room or another well used room; leave the music open on the stand, with notepad and pencil.
If a short practice session involves 5 minutes of unpacking followed by 5 minutes of packing up, it can give it more of a chore-y feeling. The more barriers to practice, no matter how small, the more likely it will seem like too much hassle, adults and kids alike. Singers, if you're driving somewhere, have a singing mix ready, try some scales or sing along to the radio. If you're driving to a your singing lessons from Brunswick, you have the perfect amount of time to warm up before seeing your singing teacher.
So there it is! If you can't manage all of the above, do what you can – it will make a difference. We can do our best to guide you in lessons, but whether singing, piano, guitar, or any instrument for that matter: practice = progress.
Please feel free to leave any comments or suggestions if we've forgotten something!


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|Carnaval Dance Festival
USBC and Infinity Baila Studios are super excited to invite you all to the star-studded 3rd Edition of "CARNAVAL Dance Festival". This year we come back bigger and stronger with 5 rooms for classes, spread over three days. The venue is the amazing Finnstown Castle Hotel - with probably one of the best ballroom floors in Ireland. We are now elevating the festival to congress level and with the packed line up of super International stars - we will naturally attract visitors not just from Ireland - but also from the Uk and mainland Europe. There will be Salsa, Bachata and Kizomba classes, from some of the most respected artists in their own genre of dance and like always there will also be offerings from our talented local Artists.
We are very excited and proud to announce the following super star line up. Coming to teach you guys are:
Salsa Artists:
Super Mario (UK)
Rodrigo Cortazar & Bersy Cortez (Mexico/Venezuela)
Gil & Shalley (Mexico/UK)
David & Johely (Venezuela)
Fidel Rodriguez (Cuba)
Angelica Duque (Venezuela)
Bachata Artists:
Antonio & Estefania (Spain)
Cristian y Gabriella (Spain)
Denis & Saray (Brazil/Spain)
Alex Maria (Ireland & Russia)
Kizomba Artists:
Felicien & Isabella (France)
Alicides MELO (Brazil)
Pratheesh Kumar (India)
and more...
We are going to introduce a 90 minutes class format this year!!!
With this new format, you will have longer classes where you can learn and practice more with your favorite artist.
We have realized that 60 minutes class is not always enough, that is why this year some classes that required a lot of details on specific techniques will be 90 minutes long, helping you to have a better understanding and longer time to practice what you have learnt.
Not all classes will be 90 minutes; we will have 60 minutes classes as well.
Already the landmark in Dublin and Ireland's winter dance calendar we want this year to be even bigger, and we hope you all put the 7th, 8th and 9th of February 2020 in your diaries.
We envisage this event will sell quickly and we encourage you to get your tickets early to avoid any disappointments.
Finnstown Castle Hotel,
Newcastle Rd, Lucan, Co. Dublin
3 days parties
3 party rooms
International & Local Shows
Buy your tickets here:


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The Icelandic brand, Gydja Collection, owned by fashion designer Sigrun Lilja, launched its first perfume over the weekend. The launch ceremony of 'EFJ Eyjafjallajokull by Gydja' took place at Debenhams in Iceland last Saturday. The 'EFJ Eyjafjallajokull by Gydja' perfume has received a lot of media attention, both domestically ... Read More...
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IBC's 2nd Annual Process Analytical Technologies for Biologics, Vienna, VA, USA
Event Jun 27
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brings together leading regulatory and industry experts to address how the implementation of PAT can greatly improve your process monitoring and control efforts. Case studies and successful approaches provided will help guide you past the compliance and regulatory hurdles associated with PAT.
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Top 10 Funny Video Game Commercials: SUPERCUT
Subscribe http://goo.gl/Q2kKrD
For this list, we've chosen the funniest game and console commercials that had us laughing long after the ad had finished airing. The commercial must have aired on television, so trailers for games were not included.
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Star Bharat's latest offering Jiji Maa is winning audience and critic's appreciations.
The Kinnnari and Jai Mehta's show is leaving no stone unturned to impress audience with intriguing drama.
As per plot, Uttara (Pallavi Pradhan) gets Niyati (Bhavika Sharma) released from the jail. After the high-voltage drama, the family will gear up for a festivity.
Now, in the coming episode, "Uttara will give a gold bangle to Niyati for 'muh dikhayi' and Falguni (Tanvi Dogra) will be happy to see her sister. Uttara will try to indirectly insult Niyati in front of everybody at the function and she would also threaten Falguni."
Meanwhile, Vidhaan (Shubhashish Jha) will be shocked when he would learn about Niyati's jail drama. Uttara will shed fake tears and will announce that Niyati was arrested for a case involving drugs. She will also insinuate that Falguni is responsible for the same.
Will Vidhaan believe Uttara?
We called Bhavika but she was busy shooting for the show.


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My friend is going to 'kill' me if he reads this. At a chanced meeting at our coffeeshop, he told me he was disappointed with S2 of Kingdom because of the lack of zombie action. There is nothing wrong with that observation. As a matter of fact, he is right, but I am reminded of one of the tenets of great storytelling – it is not the what, it is the how. Kingdom is a Korean period zombie story set in the Joseon Dynasty, but it isn't content with just populating the historical landscape with humans fighting zombies with antique weapons using archaic battle strategies. If Kingdom had catered to just the action junkies, it wouldn't be transcending into cult status. Yes, I believe Kingdom is destined to be a cult classic.
S2 benefits from an uncanny release date that feels like a grim joke. The world is presently in the deathly grip of the COVID-19 pandemic and mankind is probably in the midst of undergoing a major system reboot. Seeing the protagonists of Kingdom watching wide-eyed with disbelief written on their faces as the zombies rampage towards them in broad daylight takes on a different meaning. Reel life becomes real life. The anxiety hits really close to home.
S2 starts immediately from the cliffhanger of S1 and it doesn't let go of its grip. Replete with rich people sitting in ivory towers watching poor folks run and die, an undercurrent of classism runs through it. The central spine is still about a prince becoming a king and a female doctor coming into her own in the midst of a zombie apocalypse. S2 is relentlessly paced. Gone is the meticulous setup of place and characters, the shackles are gone. It's get-busy-living-or-get-busy-dying time. It does a great job of painting a world drowning in hopelessness, populated by humans across the spectrum. Even when faced with a common enemy, people are still selfishly looking out for themselves. Court intrigue, power struggle, double crosses still run in tandem with the zombie apocalypse, but these side-plots never bogged down the main thrust of the story.
Sandwiching the story of a crown prince becoming a true king of his people, not through status but by action, the zombie action is spectacularly riveting. There is still a macabre sense of humour embedded in certain bloody scenes where characters are dispatched in ridiculous ways that made me guffaw. Scenes of zombies swarming the landscape is jaw-dropping and inventive. The science of how the zombies work and ultimately destroyed is well-explained. In short, if you love your zombie action, this one has it in spades and in bloody refreshing ways.
I particularly enjoyed how they closed out Crown Prince Lee Chang's arc. In any narrative, what he has done through two seasons is more than enough to make him become the king twice over, but such is the way of a man who has learned benevolence and kindness that he understands the throne is an obstacle in showing love for his people. That would have been a fitting ending, but Kim Eun-hee, the writer of Kingdom, fast-forwards the story a few years later and sets up an enticing promise of S3 with some clever expositions ending with a mouth-watering cameo.
And thus begins the long wait for S3. I have mixed feelings with that not because I don't want to see how the story will progress, but it means Kim Eun-hee will have her hands full and probably won't have time for Signal S2, my favourite TV series of 2016. I will just have to be patient. Right now, I am rubbing my hands in child-like glee to see what will happen in S3.
Rating 4 of 5
4 / 5


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Arsenal's head of sports medicine Gary O'Driscoll is to join Liverpool.
Andrew Massey, who currently holds the role of head of medical services at Anfield, is set to leave the Reds on March 1st to join FIFA.
The big fat Liverpool quiz of 2019 – how much do you remember about the last year at Anfield?
As such, the Anfield outfit need a replacement, and O'Driscoll is set to be that man. However, he will not be allowed to leave the Emirates until a replacement for him has been found.
This is a blow for the Gunners. O'Driscoll, who has been with the club since 2009, has been one of the few constants in north London in recent years, and is said to be hugely popular at the club. Not only that, he is reportedly one of the best in the business as well. The Athletic even says that Mikel Arteta, the new boss at the Emirates, even tried to intervene to stop him from making the move north.
For Liverpool, though, this is fantastic news, and it will go down as a coup. Clearly, Massey was a competent man for the role, otherwise he would not be making the move to world football's governing body. But the arrival of O'Driscoll will cushion the blow of his loss, and will mean that the Reds can move on quickly.
Watch Liverpool Videos With StreamFootball.tv Below
This may not be the most exciting transfer for many supporters, but it shows that Liverpool's plans for domination goes far beyond just on the pitch at Anfield and away from home. The Reds' performances so far this term have not come just from the players and Klopp but from everybody involved in the club: from the owner, John Henry, all the way down to the kit-man.
To be able to achieve such success, everyone needs to be pulling in the same direction. Securing such a well-renowned replacement like O'Driscoll is perhaps just as important as signing the likes of Jadon Sancho and Kylian Mbappe, albeit in a different way.
Not only have Liverpool secured O'Driscoll for themselves, but they have also damaged a rival in the process. Another good day at the office for the Premier League leaders, then.
In other news, Liverpool fans discuss their failed move for this former Champions League semi-finalist.


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Dontallo Family History
14-Day Free Trial
Dontallo Name Meaning
Historically, surnames evolved as a way to sort people into groups - by occupation, place of origin, clan affiliation, patronage, parentage, adoption, and even physical characteristics (like red hair). Many of the modern surnames in the dictionary can be traced back to Britain and Ireland.
Similar surnames: Montalbo, Montalto, Montalvo, Montello, Pontillo, Donnally, Pantaleo


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You're new to Harry's team aren't you? Yes Then what makes you think that any of the slack I cut them transfers to you? Charlton Heston True Lies
Emperor Numbus Nuttus has spent the last several weeks portraying the House Intelligence committee impeachment process as some kind of a star chamber kangaroo court of a sham, with no process of fairness. He has bemoaned the fact that he could have no lawyer resent to ask questions and could call no witnesses of his own. Trump has mis-characterized the process, which is akin to a grand jury in a criminal proceeding, where the prosecution only tries to prove there is reason to move forward, not to convict. But Trump's only hope is to de-legitimize the process.
Now the scene has shifted to the House Judiciary committee, which will decide whether or not to write up and vote to release actual articles of impeachment, as well as which articles to write up and vote to forward on to the fyll House. As such, Judiciary chair Gerry Nadler has invited Trump's lawyer to participate to question witnesses, as well as to call his own. This is what Trump has been screaming for for months, and his eager response was to flip Nadler double barrel birds. If Trump participates here, it legitimizes the process, and Trump is all-in on de-legitimizing it instead,
One of the tactical choices every defense attorney faces at a trial is whether or not to call the defendant to the stand to testify. The risk is that the defendant, under vigorous cross examination, will end up doing himself more harm than good. But there are also times when a case is so daunting that the defense offers no case at all, preferring only to present a closing argument in rebuttal to the state's case. The recent Roger Stone trial is a case in point where Stoner's attorney's presented no witnesses or evidence in his behalf. Trump's defense so far has been basically the same, choosing to attack the process rather than the evidence itself.
But if the House votes to approve articles of impeachment, then the process will move on to the Senate, and a jury trial, with the 100 Senators sitting as jurors. Every juror swears an oath when accepted as a juror. I've done it twice, while serving as foreman on a personal injury case, as well as a dental malpractice vase. Jurors swear that they will listen to the evidence as presented with a fair and open mind, draw no inferences from a single piece of evidence until retired to deliberate and to follow only the judges instructions when deliberating. Basically, jurors swear that they won't be the same opinionated jerks in the jury room that they are all the rest of the time.
There are already rumblings that Trumpenstein may continue the same strategy through the trial in the Senate, refuse to participate in protest of the process. But whether The $1 Store Caligula chooses to participate or not, that process will continue to its completion. One would think that with both his presidency, as well as his place in history on the line, that Trump would want to put on some kind of defense. And he will.
Even if Trump doesn't cross examine a single witness, nor does he present a single witness of his own, or present any evidence in his defense, it doesn't mean that The Great Pumpkin doesn't have a defense. Oh, he has one alright, and it's every bit as toxic and odious as the man himself. And all it requires is an artful closing argument from his lawyer.
His form of defense has a legal name and it's called jury nullification. Jury nullification is not new, and it isn't even uniquely American dating back ti British common aw. I'll let Wikipedia explain the concept;
Jury nullification (US) or a perverse verdict (UK)[1][2] generally occurs when members of a criminal trial jury believe that a defendant is guilty, but choose to acquit him anyway because the jurors also believe that the law itself is unjust,[3][4] that the prosecutor has misapplied the law in the defendant's case,[5] or that the potential punishment for breaking the law is too harsh. Some juries have also refused to convict due to their own prejudices in favour of the defendant.[6]
That's Trump's defense against impeachment right there, and you have to admit, it has an almost artful elegance to it when you consider who's using it. Trump has sent this entire impeachment thumbing his nose at the process, and now, at the end,, he's going to keep right on doing it, thumbing his nose at the very jury deliberation and verdict process. Put on whatever evidence you want Trump is basically telling the Democrats, It won't matter, because I'll just tell the jury to forget about the evidence and let me go. And you don't have to go all the way back to colonial days to find examples of jury nullification being attempted. In the OJ Simpson trial, defense attorney Johnny Cochran nibbled at the concept of jury nullification by playing up Simpson's fame and popularity to the jury, hinting that even if Simpson were guilty, it would be a miscarriage of justice to convict him. The judge slammed Cochran for the argument, and ordered the jury to disregard it, but how do you unring a bell?
The damn closing argument nearly writes itself, especially with all of the prep work that Trump has already put into the foundation. Senate members of the jury, you have now heard the Democratic House's case. But does it really matter? After all, Donald Trump is the President, and the most popular and successful President in history. As President of the United States, Donald Trump holds great power, and with freat power comes great authority. Even if he did everything that the prosecution says that he did, and we do not concede for one minute that he did, he would still not be guilty of these crimes, simply because he is the President of the United States. There has never been a President removed from office for doing his job, and to do so now would be a travesty to everything that justice is supposed to represent. The evidence is what it is, and they can portray it to be anything they want it to be, but in your heart, you know what's just and right, and you have the chance to prove that with your verdict. Your President is trusting you to do the right thing. Thank you.
Trump has 53 GOP Senators sitting o that jury, and in pure reality he only needs 34 of them to vote his way to keep his baboon ass in office. An when you have GOP Senators like Lindsey Graham, coming right out in public and saying that they don't give a fuck. that he's not even going to read the report, it is't hard to see which way this is going to go. My realistic hope and prayer is that there will be 4 Republican Senators with enough recognition of history, and their prospective place in it, that they vote to convict, providing a majority conviction vote in the Senate, even though not enough to remove His Lowness. Hey, you gotta have dreams, even when you're up against a stacked deck.
To know the future, look to the past. before the insanity of the 2020 election, relive the insanity of the 2016 GOP primary campaign, and the general election, to see how we got to where we are. Copies of President Evil, and the sequel, President Evil II, A Clodwork Orange are available as e-books on Amazon, at the links above. Catch up before the upcoming release of the third book in the trilogy, President Evil III: All The Presidents Fen


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Decrease Cycle Time with More Advanced Moldmaking Equipment
Today's improved machine tools, tooling, workholding and CAD/CAM technology have made substantial gains over the last ten years. These advances allow shops to reduce the time it takes to machine cavities, cores, inserts and other components.
If you think an old machine is making you more money because it's already paid for, think again. Today's improved machine tools, tooling, workholding, control and CAD/CAM technology have made substantial gains over the last ten years, allowing mold makers to significantly decrease cycle times.
Better machining technology generates smoother, more accurate surfaces, which in turn reduces the need for subsequent EDM and benching operations, all of which can contribute to shorter lead times.
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STUTTGART: Porsche is planning to become the first car maker to offer music streaming service Apple Music built into a model with their upcoming Taycan.
The fully electric roadster, which formally debuts in September, integrates Apple Music into its cockpit as standard, with the service available on the touchscreen display.
Apple Music subscribers can stream via the Taycan's three-year complimentary in-car internet data roaming package, meaning crossing borders shouldn't put a stop to your driving soundtrack.
However anyone considering the car simply because of the "free" Apple Music integration should note that even the €2,500 (RM11,637) downpayment for European buyers would get you roughly a lifetime subscription to Apple Music on your smartphone.
Expected to cost upwards of US$150,000 (RM633,000), the Taycan will be Porsche's first-ever electric car when it launches on the market at the end of the year.
With Porsche's voice assistant, you can request songs, albums, radio stations or even some of the playlists specifically created by Porsche.
This is the first-ever full integration of Apple Music in any vehicle, while other, new or existing Porsche owners will also receive up to six months free of the streaming service.
"Listening to music while driving can be an electrifying feeling," said Oliver Schusser, Vice President of Apple Music and International Content. "With the Taycan (..) customers now can choose Apple Music built-in seamlessly to find the perfect soundtrack for every drive."


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You've probably heard of High Dynamic Range (HDR) Photography, it's made quite an entrance into the world of digital photography. If you haven't, the HDR process is accomplished by taking multiple exposures of a high contrast scene (usually a landscape or cityscape), at different levels of brightness, and then combining the best light from each exposure into one image. The end result is a stunning image that very closely resembles how the human eye views a scene. This process of digital manipulation has caused a bit of controversy and debate in the world of photography, especially with images that are "over-cooked." One thing is for sure though, HDR is here to stay. When done right, this unique and in depth processing technique can produce beautiful works of art that mimic the way we view and remember a landscape or scene. The above image is an example of what HDR processing can produce. This image, taken from the Big Island of Hawaii, would not be possible without HDR processing. It was taken around noon, the harshest light of the day. The first image is the best image my camera could produce given the situation. While still beautiful, there are obvious problems. Get ready, this article is going to show you how to take your digital camera and turn it into an HDR shooting machine!
2010-12-09 19:26:45


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HARD or SOFT: Why are lofts more popular than ever?
Tags: Lofts, Hard Lofts, Soft Lofts, Toronto Lofts, Toronto real estate, condos, toronto condos
I realize it is not the newest or most original topic to write about but with their recent surge in demand, mainly due to the lack of housing and larger spaces in the city, lofts have become increasingly more popular.
Some would argue that lofts are not conventional looking; they are more and more expensive to buy, the high ceilings make heating and cooling a pain and why have everything exposed and seem unfinished?
If you google 'what is a loft'? or lôft and läft, you will get a description as follows: a room or space directly under the roof of a house or other building, which may be used for accommodations or storage. Now let me be clear, this is not the type of loft I am talking about here.
The definition of a loft apartment can vary, depending on the city/region that you are in but here in Toronto the term loft pretty much describes a big adaptable open concept living space, with high ceilings and large windows often converted for residential use.
So why are they so popular right now?
Square Footage!
With the cost of houses shooting through the roof in the city, lofts are numero uno on a buyer's list as an alternative to buying a freehold house. More people work from home nowadays and lofts are perfect as a live/work space. I know many professional photographers, graphic artists, architects and filmmakers and those high ceilings and all that natural light make it the perfect creative and work environment.
The character of space in a loft is very different to that of an ordinary room. Roof lights admit more natural light than windows. Also you get a rather different view of the world from a loft than from a standard 2 storey home. In Toronto, where many older converted buildings are similar in height, the roofscape can be a much more interesting and intriguing thing to look at than walls and or a neighbour's windows.
Hard vs Soft.
What is the difference between a 'hard' loft and a 'soft' loft? You would think with them being so popular in Toronto's real estate market right now that most people would know the difference. Well, many don't. I still get asked often by buyers so in getting an education with lofts, the first step is to be able to differentiate between 'hard' and 'soft' lofts.
Once popular for their versatility and affordability amongst artistic and bohemian types, a 'hard' loft, is often a converted building from an industrial or commercial space. Some of my favourites would be the Printing Factory in Leslieville built in 1912 and the Tip Top Lofts on Lakeshore built in the 1920s, once former headquarters of Tip Top Tailors Ltd., a Canadian menswear retailer. The Broadview Lofts on Broadview and Eastern Ave., originally erected in 1914 as the Toronto warehouse of the Rexall pharmacy is by far my favourite.
In my opinion, 'hard' lofts are the real deal as far this discussion goes. Not only do you get character, but heritage and history too, with an aesthetic that traditionally showcases everything from exposed brick walls to massive windows to brilliant timber beams to uncovered electrical, plumbing, and ductwork. The ceilings in these buildings are also much higher and gives the unit an overpowering sense of space, thus the term "loft."
Hard lofts generally have more square footage. You get character, heritage and history. Most have higher ceilings and larger windows then newer-built lofts.
Hard lofts don't offer much in the way of amenities. Balconies are a rarity and older construction can mean they aren't the most energy efficient buildings.
Here's my personal favourite authentic 'hard' lofts in Toronto:
- Broadview Lofts - 68 Broadview Ave in South Riverdale
- The Printing Factory Lofts - 201 Carlaw Ave in South Riverdale
- The Tip-Top Lofts - 637 Lake Shore Blvd W in Fort York
- The Candy Factory Lofts - 993 Queen St W in Queen West
- The Brewery Lofts - 90 Sumach St in Regent Park
- Massey Harris Lofts - 915 King St W in King West
- Merchandise Lofts - 155 Dalhousie St in Church St. Corridor
However, these days most lofts aren't being converted, but rather, constructed. This would be called a 'soft' loft. 'Soft' lofts have become so common in Toronto that you're finding more and more blogs and articles like this one explaining the difference between the two.
In the case of a 'soft' loft, the buildings are new, purposely constructed for housing, and although they tend to mimic the 'hard' loft appearance, they are just that: softer.
Instead of concrete floors, they may have broadloom or hardwood. As an example, in a 'soft' loft, you'll typically observe that standard drywall encases pipes and ducts, as well as hardwood or broadloom floors replacing concrete, and so forth. While big windows and an open concept layout are still paramount, 'soft' loft units are distinctly built in a more traditional condo style. Not just via the material they utilize either, but their facilities too.
One of my favourite 'soft' lofts in the city would be The Madison Avenue Lofts at 380 Macpherson Ave. Built in 2009, it is located in Toronto's historic Casa Loma neighbourhood. Madison Avenue Lofts offers residents easy access to Yorkville and the Annex, and is just minutes from the Dupont subway station.
Soft lofts are generally more affordable. Newer buildings mean fewer structural problems and better efficiency. Most soft lofts have balconies and plenty of building amenities.
Generally 'soft' lofts are smaller units and have less square footage. You don't get the character, heritage and authenticity of a hard loft. Soft lofts often try to mimic hard lofts having the same historical value.
Here's my personal favourite newer 'soft' lofts in Toronto:
- The Madison Avenue Lofts - 380 Macpherson Avenue in Casa Loma
- The Mozo Lofts - 333 Adelaide Street East in St, Lawrence
- The Annex Loft House - 483 Dupont Street in the Annex
- The Cube Lofts - 799 College Street in Little Italy
- 75 Portland Lofts - 75 Portland Street in King West
- The Ninety Lofts - 90 Broadview Ave in Leslieville
In the end, if I had to choose I think a 'hard' loft would be the way to go. Hands down! Besides character and authenticity, you've got a property that, in my opinion, will only continue to appreciate in value. As more and more condos go up in the city, demand will keep on growing for something unique and genuine. 'Hard' lofts just cannot be duplicated.
Curious about lofts and the great benefits they offer? Any questions about my post 'HARD or SOFT: Why are lofts more popular then ever?' I want to hear from you so leave your thoughts in the comment section below.
Looking to buy, sell or refinance? Know your options. I can help! Direct line: 416-219-6662.


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TG Therapeutics Announces Phase I Data Presentation for TG-1701, a Once-Daily BTK Inhibitor, as a Single Agent and in Triple Combination with Ublituximab and Umbralisib (U2), at the 61st American Society of Hematology Annual Meeting and Exposition
Proprietary triplet of U2 plus TG-1701 (BTK inhibitor) induced 86% ORR (6 of 7) in patients with relapsed/refractory NHL and CLL at the lowest dose of TG-1701 tested
Single agent TG-1701 induced responses at multiple dose levels (including the lowest dose tested) across multiple B-cell diseases
TG-1701 demonstrates an encouraging safety profile to date, with dose escalation continuing for the combination with U2
Yesterday, TG announced positive early data from the combination of U2 plus venetoclax in an oral presentation at ASH (click here for PR)
Investor and analyst event to be held today, Monday, December 9, 2019 at 7:30 PM ET at the Hyatt Regency Orlando, featuring a fireside chat with leading clinical investigators
NEW YORK, Dec. 09, 2019 (GLOBE NEWSWIRE) -- TG Therapeutics, Inc. (TGTX), today announced the first clinical data from the Company's once daily, oral, BTK inhibitor, TG-1701, as a single agent and as a triple therapy in combination with ublituximab (TG-1101), the Company's novel glycoengineered anti-CD20 monoclonal antibody, and umbralisib (TGR-1202), the Company's oral, dual inhibitor of PI3K delta and CK1 epsilon, in patients with relapsed/refractory non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL). Data from this Phase I trial are being presented this evening during a poster session at the 61st American Society of Hematology (ASH) Annual Meeting and Exposition.
Michael S. Weiss, Executive Chairman and Chief Executive Officer, stated, "We are highly encouraged by the first clinical data presented from our once daily, BTK inhibitor, TG-1701, which has demonstrated superior selectivity for BTK compared to ibrutinib in an in vitro whole kinome screening. The data presented today show that TG-1701 is an active BTK inhibitor as a single agent and that the combination of U2 plus TG-1701 has been generally well tolerated and active with 6 of 7 patients responding to the triple therapy at 100 mg QD, the lowest dose of TG-1701 tested. We look forward to continuing dose escalation of TG-1701 in the combination arm and identifying the optimal dose for this therapy." Mr. Weiss continued, "Our goal has always been to develop the best possible combination treatment options for patients, and we are excited to present the first data from a triple combination study in which all of the agents are being developed by TG. We believe this proprietary combination has the potential to enhance the results of BTK inhibitor therapy alone and offer patients early and deep responses with a tolerable safety profile."
Below are highlights from today's poster presentation.
Poster Presentation: Phase 1 Study of TG-1701, a Selective Irreversible Inhibitor of Bruton's Tyrosine Kinase (BTK), in Patients with Relapsed/Refractory B-Cell Malignancies
This presentation includes safety information from 30 patients, 21 patients treated with single agent TG-1701, and 9 patients treated with the triple combination of TG-1701 plus U2.
TG-1701, a once daily BTK inhibitor, demonstrates an encouraging safety profile to date, with clinical and pharmacodynamic activity at all dose levels evaluated
30 patients have been treated with TG-1701 at doses that ranged from 100mg to 400mg once daily for TG-1701 monotherapy; dose escalation continues in the triple combination arm
Single agent TG-1701 produced partial responses at multiple dose levels (including the lowest dose tested) across multiple B-cell diseases, including mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), Waldenström's macroglobulinemia (WM), and small lymphocytic lymphoma (SLL)
86% (6/7) of patients treated with 100 mg TG-1701 plus U2 have achieved a response
• 4 patients with follicular lymphoma (FL): 2 Complete Responses (CR), 1 Partial Response (PR) and 1 Stable Disease (SD)
• 1 PR in marginal zone lymphoma (MZL); 1 PR in Waldenström's macroglobulinemia (WM); and 1 PR in diffuse large B-cell lymphoma (DLBCL)
All patients treated with the triple combination of TG-1701 plus U2 remain on study
ASH Poster Presentation Details
Title: Phase 1 Study of TG-1701, a Selective Irreversible Inhibitor of Bruton's Tyrosine Kinase (BTK), in Patients with Relapsed/Refractory B-Cell Malignancies
• Publication Number: 4001
• Session: 623. Mantle Cell, Follicular, and Other Indolent B-Cell Lymphoma—Clinical Studies: Poster III
• Date and Time: Monday, December 9, 2019; 6:00 PM - 8:00 PM ET
• Location: Orange County Convention Center, Hall B
• Presenter: Chan Cheah, MD, Sir Charles Gairdner Hospital, Hollywood Private Hospital, University of Western Australia, Blood Cancer Research Western Australia
Below recaps highlights from yesterday's oral presentation of U2 plus venetoclax.
Title: A Phase 1/2 Study of Umbralisib, Ublituximab and Venetoclax in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
This oral presentation includes data from patients with relapsed or refractory CLL treated with the triple combination of ublituximab, umbralisib, and venetoclax. Twenty-seven patients were evaluable for safety and 23 were evaluable for efficacy. Data highlights include:
Regimen was administered with 3 cycles of U2 induction/debulking to reduce the risk of tumor lysis syndrome (TLS), followed by the combination of umbralisib and venetoclax starting in cycle 4. Patients who were bone marrow MRD negative after cycle 12 stopped all therapy.
Overall response rate (ORR) of 87% (20/23) after U2 induction period at cycle 3, prior to introduction of venetoclax, in relapsed/refractory CLL patients, including patients refractory to ibrutinib
U2 induction appeared to reduce venetoclax TLS risk, with no patients remaining as TLS high-risk following 3 cycles of U2
13 patients treated for >7 cycles and 9 patients for > 12 cycles:
• 100% ORR (13/13) after cycle 7 for the triple combination
• 100% ORR (9/9) including 44% Complete Response (CR) after cycle 12 for the combination
• 100% (9/9) of patients had undetectable minimal residual disease (MRD) (<0.01%) in peripheral blood after 12 cycles of therapy; and
• 78% (7/9) of patients who completed 12 cycles of therapy had undetectable MRD in bone marrow and have stopped therapy
No patients (n=27) have progressed to date with a median follow-up of 6.4 months
Triple combination was generally well tolerated with no events of TLS observed
An open-label, multicenter, Phase 2 study evaluating U2 plus venetoclax (ULTRA-V) in treatment naïve and previously treated CLL is now open for enrollment.
All data presented is available on the Publications page of the Company's website at https://www.tgtherapeutics.com/publications/.
TG Therapeutics will host an event on Monday, December 9, 2019 beginning at 7:30 PM ET with a featured fireside chat beginning promptly at 8:00 PM ET. The event will take place at the Hyatt Regency Orlando, in the Plaza International Ballroom I. A live webcast will be available on the Events page, located within the Investors & Media section of the Company's website at http://ir.tgtherapeutics.com/events, as well as archived for future review. This event will also be broadcast via conference call. To access the conference line, please call 1-877-407-8029 (U.S.), 1-201-689-8029 (outside the U.S.), and reference Conference Title: TG Therapeutics December 2019 Investor & Analyst Event.
TG Therapeutics is a biopharmaceutical company focused on the acquisition, development and commercialization of novel treatments for B-cell malignancies and autoimmune diseases. Currently, the company is developing two therapies targeting hematological malignancies and autoimmune diseases. Ublituximab (TG-1101) is a novel, glycoengineered monoclonal antibody that targets a specific and unique epitope on the CD20 antigen found on mature B-lymphocytes. TG Therapeutics is also developing umbralisib (TGR-1202), an oral, once-daily inhibitor of PI3K-delta. Umbralisib uniquely inhibits CK1-epsilon, which may allow it to overcome certain tolerability issues associated with first generation PI3K-delta inhibitors. Both ublituximab and umbralisib, or the combination of which is referred to as "U2", are in Phase 3 clinical development for patients with hematologic malignancies, with ublituximab also in Phase 3 clinical development for Multiple Sclerosis. Additionally, the Company has recently brought its anti-PD-L1 monoclonal antibody, TG-1501, its covalently-bound Bruton's Tyrosine Kinase (BTK) inhibitor, TG-1701, as well as its anti-CD47/CD19 bispecific antibody, TG-1801, into Phase 1 development. TG Therapeutics is headquartered in New York City.
Cautionary Statement
Some of the statements included in this press release may be forward-looking statements that involve a number of risks and uncertainties. For those statements, we claim the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. In addition to the risk factors identified from time to time in our reports filed with the Securities and Exchange Commission, factors that could cause our actual results to differ materially are the following: our ability to successfully and cost effectively complete preclinical and clinical trials; the risk that data from the UNITY-CLL Phase 3 trial will not be available in the planned timeframe or not be sufficient to support a regulatory filing; the risk that the highlighted early clinical trial results, that may have supported the acceptance of our data for presentation or influenced our decision to proceed with additional clinical trials, will not be reproduced in future studies or in the final presentations; the risk that the combination of ublituximab (TG-1101) and umbralisib (TGR-1202), referred to as U2 and being studied in the UNITY clinical trials, will not prove to be a safe and efficacious combination, or backbone for triple therapy combinations; the risk that the combination of U2 plus venetoclax will not prove to be a safe or efficacious treatment and will not warrant further testing; the risk that the combination of U2 plus venetoclax will not ultimately result in a time limited therapy; the risk that the combination of U2 plus venetoclax, if approved, will not be utilized broadly or at all by academic or community physicians; the risk that the preliminary results for TG-1701 will not be reproduced in additional data sets; and the risk that future results from the combination of U2 plus TG-1701 will not be comparable in safety, efficacy, or both, to the early results presented or to those results previously seen with the combination of U2 plus ibrutinib. Any forward-looking statements set forth in this press release speak only as of the date of this press release. We do not undertake to update any of these forward-looking statements to reflect events or circumstances that occur after the date hereof. This press release and prior releases are available at www.tgtherapeutics.com. The information found on our website is not incorporated by reference into this press release and is included for reference purposes only.
Jenna Bosco
Senior Vice President,
Corporate Communications
TG Therapeutics, Inc.
Telephone: 212.554.4351
Email: firstname.lastname@example.com


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Visiting Gulgong in the Mudgee region of country NSW is like taking a trip right through regional Australia in the 19th century. This former gold mining town still feels like it might have in the 1870s when people came here seeking quick fortunes.
Walk through history
Gulgong is home to around 130 National Trust-listed buildings, many complete with their original verandahs and iron-lace balconies. You can also see Australia's oldest operating opera house, the Prince of Wales Opera House, which opened in 1871, and where the great Dame Nellie Melba once performed.
Gold fever struck the region in 1870, when payable gold was found at Red Hill and 20,000 people flocked to the area. Prior to that, Gulgong was just a sheep-run, a large property for raising sheep. Learn about the gold rush at the Gulgong Pioneers Museum and on the Gulgong Gold Experience.
Celebrate Henry Lawson
The great Australian writer and bush poet Henry Lawson spent his childhood in the area. Discover more about his cultural legacy at the Henry Lawson Centre. Scenes of Lawson's childhood years in gold towns such as Gulgong appeared on the first Australian $10 note.
The town celebrates Lawson's life with the Henry Lawson Heritage Festival every June long weekend. Other fun annual festivals are the Gulgong Folk festival in December and the Gulgong Gold and Mining Festival in October. The biennial Clay Gulgong attracts ceramists from around the world.
Things to do
Other things to do in and around Gulgong include wine tasting at wineries and exploring the sprawling Goulburn River National Park. In this riverside wilderness east of Gulgong, spot emus, red-necked wallabies and turquoise parrots, and go fishing, hiking and camping.
Getting there and where to stay
Gulgong is a four-hour drive from Sydney and 20min from Mudgee. You can also fly into Mudgee Airport or take the train and coach. Accommodation options in Gulgong suit various budgets and include motels, restored colonial cottages and a heritage motel.


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1999 | OriginalPaper | Chapter
Government and Administration
Author: Jeremy Black
Publisher: Macmillan Education UKLog in
The nature of government in this period, its objectives and achievements, can be approached from a number of angles. Much of the discussion has revolved around the notion of Enlightened Despotism or, as it is sometimes described, Enlightened Absolutism. This suggests that many governments, particularly in the second half of the century, were influenced in the formulation and implementation of their policies by ideas associated with the Enlightenment and that government became a means to implement an Enlightenment agenda. The validity of this concept has been much debated, which is scarcely surprising as it shares the ambiguity and amorphousness that characterises the very notion of the Enlightenment itself. Furthermore, Enlightened Despotism is sometimes discussed in a manner that implies that states or governments were in some fashion separate from and acting upon society. Such a view, which was indeed sometimes taken, tends to lead to a presentation of government and society in adversarial terms and to treat the disparity between policies and their implementation accordingly.


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By Peter Doggers for chess.com
After winning the rapid, Hikaru Nakamura has good chances to also take the first prize at the blitz part of the Tata Steel Chess India tournament in Kolkata. The American grandmaster scored 6.5/9 and is half a point ahead of Wesley So.
Monday was a rest day in the tournament, but the players did pay a brief visit to the tournament hall. A one-hour Q&A was organized for the many chess fans that are visiting each day, followed by an autograph session. Although it's only the first time that this event is being organized, the turn-up is great. It's clear that the presence of top grandmasters is something special in this city.
In the evening, almost all players joined for a dinner party thrown by the owner of the organizing company Gameplan, and some of them even warmed up a little for some friendly blitz. It should be mentioned that co-commentator IM Lawrence Trent is a very decent blitz player, and one of his scalps was none other than former world blitz champion Sergey Karjakin.
Stick to 1...e5 today, Seryozha! :) The blitz portion of @tschessindia kicks off in 20 minutes on https://t.co/Pu5cY8bp13 where I'll be bringing you all the action with the delectable @TaniaSachdev. Also welcome @rpragchess - he's determined on causing a few upsets! @chesscom pic.twitter.com/pp7bK2dxN6— Lawrence Trent (@LawrenceTrentIM) November 13, 2018
On Tuesday the first set of nine rounds of blitz was played, and during the first half, it was the Nakamura show. Scoring 4.5/5, the American player was already 1.5 points ahead of the pack. Finishing with four draws was enough to keep the sole lead, but the gap has decreased to half a point going into the final day.
With his pet system 1.Nf3 and 2.e3, Nakamura didn't get too much against Surya Shekhar Ganguly but just one inaccuracy by the latter was enough to get into trouble, and lose quickly:


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March Already.
We have been really busy these past few weeks. What with the kitchen installation (still not totally finished as there is a door missing ) and other decorating duties (and I loathe decorating) plus joining a channel manager to increase our exposure online, the winter sort of passed us by! Now all of a sudden spring has sprung and there is colour in the garden and we are just not ready for spring and gardening etc How can it be March already! At this rate it will be Christmas in September!!
Just to remind you, for best booking rates please e-mail me directly from our website, I reply within a couple of hours usually, unless overnight.