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Here you will find a wide range of activities for all ages based in Keswick, right in the heart of the British Lake District, World Heritage Site. Our friendly and experienced staff will be able to help find the right activity for you.
There's a wide range of activities that we're able to offer to keep even the most frequent user happy all year round!
The climbing area consists of a multitude of angles from slabs to steep overhangs around the main area, including a Moon Board in our Bouldering Area to get your arms pumping! Tucked away behind all this is our indoor caving system; crawl, squeeze and weasel your way through from the bottom of the climbing wall to the cavern before exiting out of the cave into our cafe upstairs.
If you have tried everything indoors or would just like to take on a challenge outdoors, we have a wide range of outdoor activities available to suit all abilities – including Rock Climbing, Ghyll Scrambling, Mine Exploration and Via Ferrata!
Off on your own adventures? Then why not check out our independent outdoor store specialising in Climbing, Mountaineering and Running!
Free UK Shipping on orders over £50
Heads Road, Cumbria, CA12 5EZ
Season : AW18
Code : KUHL130GM
Weight : 0.4KG
A truly beautiful jacket, and upon donning it is rumoured you'll gain all the sagely wisdom of a high Zionist Monk, whilst having the style of Johnny Depp.
This is what the folks at cool have to say:
The KÜHL BURR™ JACKET is a rugged yet soft canvas classic that's ready for anything and everything. Featuring 100% combed Cotton canvas with KÜHL's exclusive Patina finish, the BURR JACKET combines durable versatility with timeless style.
The lined, micro fleece chest keeps your core warm, while supplex-lined sleeves allow easy on/off. Saddle stitching reduces bulk, and YKK zippers provide reliable performance.
The BURR JACKET features generous hand pockets, a zippered chest pocket, and a hidden security pocket for valuables. With secure storage, long-lasting construction and KÜHL's signature style, the BURR JACKET is a favorite for fishing, hunting, camping, hiking, and travel.
8/10 Would not look out of place in the first class lounge of the Titanic.
Free Delivery is for all orders over £50
For next day delivery orders must be placed before 13:30. Any order placed after this time with next day delivery selected will still be charged the full rate but may not arrive until 2 days after the order was placed. Please note that our courier does not deliver on weekends. This means that any orders placed with next day delivery on Saturdays or Sundays, won't arrive until Tuesday. Orders placed before 13:30 on a Friday will arrive on Monday.
We make every effort to ensure that your order is delivered to you undamaged and in working order, however, damage can occur during transport. If your order arrives damaged, missing items or with the wrong items, you must notify us within 7 days. If we receive no such notification the order will be deemed as satisfactory by the customer. Any subsequence returns or exchange after this may incur additional charges as laid out in the Returns & Exchanges section.
We use primarily Royal Mail, DPD and APC, but may also use other delivery companies. We cannot be held responsible and accept no liability of any lost order, damaged product(s) or delayed and/or failed deliveries caused by them, as once our order is handed to them it is their responsibility to ensure its delivery.
View our full delivery information
Our Click & Collect service offers all the benefits of shopping online combined with specialist personal retail experience in one of our stores. Simply order your items, select Click & Collect and pick up your item at a time that's convenient for you. Best of all the service is completely FREE!
1. Add your items to your basket
Use our website to browse our catalogue of products with stock availability. When you find the item you want simply add it to your basket like you usually would.
2. Checkout using Click & Collect
Scroll down and choose Click & Collect as your delivery method. Enter your postcode at the checkout to find your closest store.
3. Choose the store of your choice and collect your items
Choose a store of your liking, click continue and complete the rest of our standard checkout steps and you're ready to collect your item in store.
When can I collect my order?
For items in stock at the chosen collection store, we will normally have your item ready to collect within 1-2 working days.
For items which are at the warehouse your order will be ready to collect in the time indicated on the website; or if at another store approximately 3 working days – please call in advance if you are making a long journey, just in case!
How will I know when my order is ready?
For every order we will send you an e-mail to let you know when your order is ready to collect. If you've ordered a bike we will contact you once you have placed your order to arrange a collection time.
What do I need to collect my order?
Please bring with you your confirmation e-mail, a photo proof of ID (i.e. passport, driving licence), and proof of address.
We will hold your order in store for 10 days, if you have any problems with getting to the store to collect your order please feel free to contact the collection store and we will happily extend this time where possible.
Can Someone Else Collect My Order?
Please contact the store you have chosen to collect from in advance and we will do our best to accommodate any changes relating to collection.
How do I cancel/change my order?
If you wish to cancel your order or make any changes please contact the store directly, contact information can be found here. Please note, full refunds will be made via the original transaction made with our online team.
How do I return my order?
Our normal returns policy applies to all Click & Collect orders, for more information see our returns policy. You can also return directly to the store.
View our full Click & Collect information
Hassle free returns
Return, Exchanges and refunds requests can be initiated by one of the following two options:
In Store
Please bring the product(s) to our High Street Store on Heads Rd, Keswick along with the receipt.
By either filling in the returns form or putting a covering note in with your name, order number and course of action requested. Then posting them back to:
F.A.O. Returns, Kong Adventure, Heads Road, Keswick, Cumbria, CA12 5EZ
We strongly recommend you use suitable packaging to ensure their safe transit, and use a recorded/insured delivery service, as we will not be held responsible for returned goods lost or damaged in transit.
Download Returns and Exchange Form
If you wish to return or exchange an item that you have purchased online or at our High-Street Store all items must first meet the following criteria, in addition to other conditions outlined below.
• All Items must be returned in a new and unused condition
• They must have all the original packaging, labelling and tags
• Be complete, with any additional accessories or stickers supplied returned as well
• Returned with the original Receipt/Packing Slip.
If an item develops a fault the following criteria must also be met.
• The faulty item must be returned to KONG Adventure Clean and Dry. KONG Adventure reserves the right to charge a customer a cleaning fee of £5 if an item is return dirty.
• The Fault must have been caused during "normal use" for the item. No action will be taken if the fault has occurred due to miss use of the product
• The item must be assessed by a KONG Adventure member of staff. This can be done by bring in to our High-Street Store or by posting.
If a product is returned and does not meet all of the above criteria KONG Adventure holds the right not to process the refund/return/exchange
1. Any unused and unworn items, with the exception of items ordered specially and items sold as "shop soiled" or reduced, can be exchanged or refunded within 30 days of purchase.
2. Any faulty goods returned within 30 days of purchase with minimal wear and accompanied by proof of purchase will be exchanged for an identical item or refunded. Please note this may require KONG Adventure to order that item in.
3. Any faulty goods returned more than 30 days from purchase and accompanied by a proof of purchase may be sent for repair, or replacement or refunded at the Managers discretion.
4. Where a fault or the cause of the fault is not apparent to our staff we reserve the right to send the item for testing before deciding on any action to be taken
5. Any faulty goods returned showing wear and which cannot be reasonably repaired may have an amount deducted from the refund or credit note
6. Where an item was purchased by Credit/Debit card then any refund must be made on the same Credit/Debit Card
This policy is in addition to and does not affect your Statutory Rights.
All Items bought online have the RIGHT TO BE CANCELLED within a 14 day period.
1. A cancellation request must be submitted within 14 days of purchase either by EMAIL or phone – 017687 75907
2. Orders cancelled within 14 days will receive a full refund including postage and surcharges
3. It is up to the customer to pay for the return postage
4. The RETURNS FORM will need to be filled in and forwarded to KONG Adventure
5. Proof of postage must be obtained and a copy EMAILED to KONG Adventure
6. The Item must be returned within 14 days of the cancellation request
7. The refund will not be processed until the item has been received instore and items checked to ensure they meet all the criteria outlined above.
Most items can be returned to KONG Adventure and the customer issued a full refund or exchanged within 30 days of purchase. However, some items are not included, please see below for details
1. A return or exchange request must be submitted within 30 days either by EMAIL or phone – 017687 75907
2. Orders returned/exchanged between 14 -30 days will only receive a refund for items purchased, the postage cost and surcharge will not be refunded.
3. The customer is required to pay for the return postage.
4. The item must be returned within 14 days of the return/exchange request
5. In the case of exchanges KONG Adventure will pay for the replacement item to be posted to the customer one additional time. For any subsequent exchanges the customer will be required to pay for the postage for the returning item and for the new item being sent out.
6. The RETURNS FORM should be printed out, completed and mailed back with the item.
7. Proof of postage should be obtained and an EMAIL sent to KONG Adventure
8. The refund/exchange will not be processed until the item has been received back instore and the item(s) checked to ensure they meet all the above criteria.
KONG Adventure take every precaution to try and ensure that all items are delivered in good working order and undamaged, however we understand that some damage may occur during transport. Similarly, mistakes could be made while packing or the wrong item sent by mistake.
1. KONG Adventure must be informed of any damaged, faulty or wrongly delivered items within 14 days of delivery.
2. The item will need to be posted back to KONG Adventure along with the completed RETURNS FORM within 14 days of notifying them.
3. Once the item has been received by our high-street store and any damaged, faulty or incorrectly delivered item has been confirmed by a member of staff, a full refund or replacement will be processed.
4. In the case of a refund, KONG Adventure will refund the full amount paid, including the original postage and surcharge and the postage paid to return the item. Proof of cost must be supplied.
5. In the case of a replacement KONG Adventure will pay for the post of the new item to be sent out and a refund will be issue for the cost of sending the item back. Proof of cost must be provided.
i) In some cases, this will mean KONG Adventure may have to order in new stock. You will be informed of this at the time and a time frame will be given. It is up to the customer if they wish to wait for the item to come into stock or take a refunded instead. KONG Adventure can not be held accountable for any delays to this time frame caused by its suppliers.
KONG Adventure sell items that are considered Personal Protection Equipment (PPE). Due to the nature of PPE, we cannot accept any returns or Exchanges on these products. These items include but are not limited to; harness, ropes, belay equipment, karabiners, helmets, climbing protection. If you are unsure whether the item you are purchasing is classed as PPE please contact KONG Adventure.
This is in addition to and does not affect your Statuary Rights.
View our full Returns Policy
With Pre-Order, you can purchase the latest items added to our store in advance of them arriving with us.
You Pre-Order is prioritised (at no additional charge); meaning that, as soon as the product arrives with us, we can wrap it straight back up and get it sent out to you - it often never even hits the stock room shelves!
With Pre-Launch, the date when we expect to receive the product ourselves is still a little too hazy to be confident in accepting Pre-Orders.
So, instead, you can submit your email address against the item you are interested in and we will email you as soon as stock arrives on the system.
Estimated Delivery Dates are given on Pre-Order and Pre-Launch products. They are for indication purposes only and can change at any time without notice.
The dates we provide are based on indications given by our suppliers. Whenever we get updated information from our suppliers we will endeavour to update the Estimated Delivery Dates provided on product pages.
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On March 8, Catholics from around the state traveled to Albany for the annual "Catholics at the Capitol" day, sponsored by the State Bishops' Conference. The purpose of the day is to offer Catholics an opportunity to stand together on the broad range of issues of concern to us — protecting life, strengthening our schools, caring for the poor and sick — and to speak to our state legislators.
One of the issue papers distributed by the Conference was entitled "Making Abortion Rare". This document explained our Church's opposition to the radical Reproductive Health Act, a bill that would lead to an increase in abortion, by placing it beyond any reasonable regulation. A second issue was our opposition to the Governor's elimination of all funding for the Maternity and Early Childhood Foundation. That foundation supports local initiatives and organizations that offer alternatives to abortions, and have helped thousands of women have their babies.
These positions are a practical response to the challenge issued by Archbishop Dolan at his press conference in January about the appalling abortion rate in New York City: "I invite all to come together to make abortion rare, a goal even those who work to expand the abortion license tell us they share."
Some of our pro-life supporters have expressed discomfort with saying that we wish to "make abortion rare". They are worried that this might imply that we are conceding the legality of abortion, and that we have given up our ultimate goal of defending every human life.
This concern is understandable, because people rightly can't be satisfied with anything short of full protection for the unborn. I understand this concern, but I believe it is unfounded.
Our ultimate goals in this struggle have never changed. Nobody has any doubt about the position of the Catholic Church on abortion. We are absolutely, unalterably, irrevocably opposed to legal abortion, and will never accept the legitimacy of laws that permit it. We hold steadfastly to building a culture of life in which every life is valued in our society and its laws.
But while we pursue those ultimate goals, we have to take into account the political and cultural situation in which we find ourselves. Then, relying on the virtue of prudence, we have to mitigate the harm that is being done by legalized abortion, and try to achieve realistically attainable results to advance the culture of life.
This approach was outlined in Pope John Paul II's encyclical, The Gospel of Life:
The Church well knows that it is difficult to mount an effective legal defense of life in pluralistic democracies, because of the presence of strong cultural currents with differing outlooks. At the same time, certain that moral truth cannot fail to make its presence deeply felt in every conscience, the Church encourages political leaders, starting with those who are Christians, not to give in, but to make those choices which, taking into account what is realistically attainable, will lead to the re- establishment of a just order in the defense and promotion of the value of life. (90)
The challenge to "make abortion rare" is just such an initiative. It takes into account the political and cultural fact that a complete abrogation of abortion laws is not attainable in our current cultural and legal climate. It is directed not to people who are already committed to the cause of life. Instead, it is an appeal to those who consider themselves "pro-choice", but are uncomfortable with abortion and may be open to work with us on practical measures to reduce it.
In other words, it is an effort to change hearts, to rebuild the foundation for a true culture of life. As hearts change, laws will follow.
Our vision and our goals will always remain the same. As the United States Bishops said in their statement, Living the Gospel of Life:
The Gospel of Life must be proclaimed, and human life defended, in all places and all times. The arena for moral responsibility includes not only the halls of government, but the voting booth as well. Laws that permit abortion, euthanasia and assisted suicide are profoundly unjust, and we should work peacefully and tirelessly to oppose and change them. Because they are unjust they cannot bind citizens in conscience, be supported, acquiesced in, or recognized as valid. Our nation cannot countenance the continued existence in our society of such fundamental violations of human rights. (33)
Tags: Abortion, New York State Catholic Conference, Pro-Life

subset: commoncrawl


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Palestinians gather in South Hebron Hills for 6th annual Popular Resistance Festival. All photos by Eugene Peress.
Villages in the South Hebron Hills experienced three days of continuous Israeli army and settler violence between the 4th and 6th of July. The escalation of violence occurred just days after the sixth annual Popular Resistance Festival was held in the village of Khalett Athaba, located in Israeli Firing Zone 918 in the hills south of Hebron.
On Thursday, July 4th the Israeli army invaded the village of Jinba in the South Hebron Hills wrecking numerous homes in the small village. In the middle of the night thirty Israeli soldiers invaded Jinba village, throwing stun grenades, beating four boys with their guns and arresting three men.
The following day some fifty settlers accompanied by eight armed soldiers went on a "sightseeing tour" of Israeli ruins through the South Hebron Hills villages of At Tuwani, Ar Rakeez and Al Birkeh. Hours later the Israeli army conducted military training in Humra valley in the South Hebron Hills. The training was held adjacent to At Tuwani village and the illegal Israeli outpost of Havat Ma'on.
On the evening of Friday, July 5th Settlers attacked and injured a mentally disabled Palestinian shepherd in the village of Tuba in the South Hebron Hills. Four settlers assaulted Meher Isa Aliawad while the Palestinian man was grazing his flock. Settlers threw stones at him as he was trying to run back home, seriously injuring Aliawad's left arm.
On Saturday morning, July 6th Palestinian shepherd Heir Suliman was arrested near the Bedouin village of Umm Al Kheer while returning home with his flock. According to the international group Operation Dove Israeli soldiers provided no reason for the man's arrest. The same day four Israeli activists were arrested and taken to the police station of Kiryat Arba settlement after they started protesting against the arrest of the Palestinian shepherd.
A Palestinian home in the village of Khalett Athaba, South Hebron Hills
Hafez Huraini, coordinator for the Popular Resistance Committee in the South Hebron Hills spoke to Palestine Monitor about these actions. "This is the kind of strategy of the occupation to evict Palestinians out of this area. It is done by using these different aggressive policies by the military administration as well as settler violence. There is full coordination on how to make Palestinian life harder and harder and push them to leave."
Violence and subsequent arrests broke out just days after South Hebron Hills residents, together with international and Israeli activists, celebrated their continued non-violent struggle on Saturday, June 29th in the village of Khalett Athaba. The Festival, organized by the South Hebron Hills Popular Resistance Committee, commemorated the resident's choice of non-violent resistance against the Israeli occupation, settler violence, army harassment and continuous attempts to evict the villagers.
"This festival is a really important activity because we can send a message to everyone about the most important issue. This festival is the fifth one and as you see we talk about the firing zone 918. We all are pushing to stop the eviction of the Palestinians from this area," – Hafez Huraini told Palestine Monitor.
South Hebron Hills residents began their peaceful struggle against occupation after approximately 700 people from twelve small villages were forcefully evicted from their land by the Israeli military in 1999. Orders for eviction were given on the grounds that villagers "illegally" lived in a live-fire zone.
The area of this live fire zone is nearly 30,000 dunums (3,000 hectares), and was declared a restricted military zone in the 1970s. According to the United Nations Office for the Coordination of Humanitarian Affairs approximately 18% of the West Bank has been designated as a closed military or "firing zone". This is roughly the same percentage of the West Bank designated Area A (17.7 %), the only portion of the territory that is under full Palestinian Authority control.
Attendees gather outside a tent at the popular resistence festival
"We [popular committees] started our work in 1999 after the first eviction. They [Israeli authorities] tried to evict fifteen villages. After that time we started organizing ourselves by creating local committees in each village and started to use this coordination in an effective way. After long discussions and meetings we decided on this choice – non-violent resistance as an effective way to put an end to the occupation. This is the main principle for us," – said Hafez Huraini.
Twelve Palestinian villages are located in the area of Firing Zone 918, the residents under constant threat of forced expulsion from their lands. In July 2012 Israeli Defense Minister Ehud Barak ordered the demolition of eight of the villages located in the military firing zone that, if carried out, would result in expulsion of over 1,000 people, more than half of them children. On January, 16th 2013 the Association for Civil Rights in Israel filed a new petition to the High Court of Justice on behalf of the villagers after previous petitions were dismissed. The court hearing for the new petition is set for July 15.
Despite the threats of imminent demolition, displacement , and settler and Israeli army violence South Hebron Hills residents are committed to non-violent resistance against the illegal Israeli occupation of Palestinian lands.
As Hafez Huraini said "We are quite aware of the policy of the occupation - the goal is to evict the Palestinians. At the same moment they are pushing the Palestinians forcefully to respond in a violent way, to lose hope and just go to the violent way. If we respond violently they [Israeli authorities] will find excuse to implement their policy. We are aware of that policy and we are committed to the choice of non-violent resistance. You need to organize for that and work to organize demonstrations, activities, to resist the occupation and settlement expansion."
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i am french Sorry if my writing is not very good
so I have a problem with the instalation of qtranslate:
I'm on localhost with xampp, my version of wp 3.5.1
I installed and activated, but I have an error message:
"qTranslate Services could not load OpenSSL!"
I open my localhost with https://
is there a solution?
What can I do?
Thank you for your answers


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Get piecing in no time with Anita Grossman Solomon's innovative techniques for cutting and assembling four classic quilt blocks.
Over years of quilting, Anita has figured out how to let her tools do most of the persnickety work of precise measurement. Snip snip snip! She'll show you how to customize your own rulers, use paper patterns for cutting and sewing, and deploy her stack-and-stitch method of block creation. "Why didn't I think of that?" you'll wonder as you breeze through Anita's arrowhead, pineapple, square-on-point and "unbiased" blocks. Anita will also go over fabric preparation and how she chooses her fabrics and arranges the blocks for her stunning quilts.


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A Six Hour Beanie
It was really stupid of me to make this in one sitting but it was one of those I'm-so-close-to-finishing-I-should-just-finish-it-even-though-i'm-dying moments. My wrists are paying for it today.
It's this pattern but I got rid of two sts per repeat and worked the decreases every row for a smaller beanie version.
Lily's also injured; she landed incorrectly after an epic frisbee catch. Poor thing doesn't understand why she can't run.
My sister's birthday celebration was pretty low key on Saturday. I gave her her beloved turkey jerky from Trader Joe's andwent to Polly's Pies for dinner. The dessert came from Porto's and while it was delicious, I was way disappointed in their service. I asked for a dozen rolls to be split in two boxes and was informed I would be charged for the additional box and wouldn't be given the dozen discount…what? I'm still ordering a dozen and they give boxes on the other side for free. Wack. (How much I would have saved is so not the point. )
Did you have a good weekend?
ellingsenphoto permalinkApril 3, 2012 8:22 am
Poor Lily! Don't you hate when you have to try to keep them still? That might be the worst part about being a dog parent, is you can't explain things to them. I'm glad you and your sister had fun, despite the wackness. 🙂


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I'm hoping that someone can help me and identify some of the houses in Baring street were demolished. My Great, Great Grandfather died at 134 Baring St in 1897. At the time he was staying with his sister (Rebecca Hutchinson). Any information or any photos would be fantastic.
Many Thanks
134 Baring Street South Shields in 1897
local History for Tyne & Wear, please leave your false teeth & walking sticks at reception
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CyFlow™ CD3 Purified
|Alternative Name:
|Leu4, T3
|Flow cytometry, Functional assays, Immunoprecipitation
|Field of Interest:
|Regulatory Status:
|Source Species:
|Target Species:
|Product number:
For Research Use Only
|HLDA Workshop
|HLDA IV—WS Code T 97
|Concentration Unit
|0.1 mg
|0.1 mL
|Human thymocytes and T lymphocytes
|Background Information
|CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3γ, CD3 δ, CD3ε and CD3ζ. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.
|Storage Buffer
|The reagent is provided in Tris buffered saline (TBS) solution, pH ≈8.0, containing 0.09% (w/v) sodium azide.
|Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
|Do not use after expiration date stamped on vial label.
| Knapp W, Dorken B, Gilks W, Rieber EP, Schmidt RE, Stein H, von dem Borne AEGK (Eds): Leucocyte Typing IV. Oxford·University·Press,·Oxford. 1989; 1‑1820. <·NLM·ID:·8914679·> | Soucek J, Hilgert I, Budová I, Lindnerová G: Augmentation of NK cell activity and proliferation in cultured lymphocytes of leukemic patients by monoclonal antibodies CD3 and interleukin‑2. Neoplasma. 1994; 41(2):75‑81. <·PMID:·8208318·> | Stefanová I, Saville MW, Peters C, Cleghorn FR, Schwartz D, Venzon DJ, Weinhold KJ, Jack N, Bartholomew C, Blattner WA, Yarchoan R, Bolen JB, Horak ID: HIV infection‑‑induced posttranslational modification of T cell signaling molecules associated with disease progression. J·Clin·Invest. 1996·Sep·15; 98(6):1290‑7. <·PMID:·8823293·> | Brdicka T, Imrich M, Angelisova P, Brdickova N, Horvath O, Spicka J, Hilgert I, Luskova P, Draber P, Novak P, Engels N, Wienands J, Simeoni L, Osterreicher J, Aguado E, Malissen M, Schraven B, Horejsi V: Non‑T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling. J·Exp·Med. 2002·Dec·16; 196(12):1617‑26. <·PMID:·12486104·> | Brdicková N, Brdicka T, Angelisová P, Horváth O, Spicka J, Hilgert I, Paces J, Simeoni L, Kliche S, Merten C, Schraven B, Horejsí V: LIME: a new membrane Raft‑associated adaptor protein involved in CD4 and CD8 coreceptor signaling. J·Exp·Med. 2003·Nov·17; 198(10):1453‑62. <·PMID:·14610046·> | Stroncek DF, Caruccio L, Bettinotti M: CD177: A member of the Ly‑6 gene superfamily involved with neutrophil proliferation and polycythemia vera. J·Transl·Med. 2004·Mar·29; 2(1):8. <·PMID:·15050027·> | Batista A, Millán J, Mittelbrunn M, Sánchez-Madrid F, Alonso MA: Recruitment of transferrin receptor to immunological synapse in response to TCR engagement. J·Immunol. 2004·Jun·1; 172(11):6709‑14. <·PMID:·15153487·> | Huang Y, Wange RL: T cell receptor signaling: beyond complex complexes. J·Biol·Chem. 2004·Jul·9; 279(28):28827‑3. <·PMID:·15084594·> | Kuhns MS, Davis MM, Garcia KC: Deconstructing the form and function of the TCR/CD3 complex. Immunity. 2006·Feb; 24(2):133‑9. <·PMID:·16473826·> | Alarcón B, Swamy M, van Santen HM, Schamel WW: T‑cell antigen‑receptor stoichiometry: pre‑clustering for sensitivity. EMBO·Rep. 2006·May; 7(5):490‑5. <·PMID:·16670682·> | Meraner P, Horejsí V, Wolpl A, Fischer GF, Stingl G, Maurer D: Dendritic cells sensitize TCRs through self‑MHC‑mediated Src family kinase activation. J·Immunol. 2007·Feb·15; 178(4):2262‑71. <·PMID:·17277131·>


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First she tweeted to the Senate Majority Leader. Then she released a video addressed to that entire august body. Now, Lady Gaga is holding campaign-style rallies to help end "Don't Ask, Don't Tell."
The iconoclastic pop star appeared in Portland, Maine, on September 20 at a rally held by the Servicemembers Legal Defense Network in an effort to pressure the state's two Republican senators to vote to allow for the controversial policy to be repealed, reports the Huffington Post.
In front of a crowd of 2,000 assembled at Deering Oaks Park and flanked by members of the armed forces who have been discharged under the 1993 policy, Gaga fulminated against the law and called it an injustice. She even went as far as to say that a new policy should be created that targets straight soldiers who are "uncomfortable" serving with gay soldiers.
U.S. & World
News from around the country and around the globe
"Our new law is called 'If you don't like it, go home!" she said.
Perhaps given the seriousness of the setting and the event, Gaga eschewed her typically outrageous attire and appeared onstage in a black blazer, tie, black-rimmed glasses and a blonde wig.
The House has already approved the defense authorization bill that includes a repeal of "don't ask," but 60 senators are needed to cut off debate and proceed to a vote on the bill. A vote is scheduled for September 21.
Maine's senators, Susan Collins and Olympia Snowe, could prove to be critical votes. Collins previously voted to end the policy in the Armed Services Committee, but has said that she wants a "full and open debate" on the defense bill and requested that members of the GOP be allowed to offer amendments.
A spokesman for Snowe said that she has not decided how to vote.
Gaga was escorted to this year's MTV Video Music Awards by ex-servicemembers who had been discharged under the policy.
Selected Reading: Huffington Post, Yahoo, MTV


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Alicia: My Story
Bantam Books, 1988 - 356 Seiten
Her name is Alicia. She was thirteen when she began saving the lives of people she did not know--while fleeing the Nazis through war-ravaged Poland. Her family cruelly wrenched from her. Alicia rescued other Jews from the Gestapo, led them to safe hideouts, and lent them her courage and hope. Even the sight of her mother's brutal murder could not quash this remarkable child's faith in human goodness--or her determination to prevail against overwhelming odds.
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Story tells of how a Girl has to turn into a survivor. Vollständige Rezension lesen
Great storyNutzerbericht - book keeper - Borders
Love this book. You will laugh, cry and learn a lot. A must have on your shelf! Vollständige Rezension lesen
Before the War
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From Hinton to Hamlet: Building Bridges Between Young Adult Literature and ...
Sarah K. Herz,Donald R. Gallo
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Erased: Vanishing Traces of Jewish Galicia in Present-day Ukraine
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Home > Storage > Cupboards & Bookcases > Infinity Office Storage
Inifinity storage range is a modular system designed to compliment a wide range of our furniture collections.
Infinity range is made entirely in the UK and includes a 7 year guarantee as standard.
Bespoke desk sizes available on request.
(Details shown apply to the default selection)
Weight: 94.64kg
Delivery: No charge
Made to order, 21-28 days
Frame: MFCSurface: MelamineApplication: OfficeGuarantee: 5 YearsCountry of Origin: UK
Some finishes may be available offline only, please contact Kirkhouse with any queries.
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The planet matters. Communities matter. And, you matter. At DS Services®, we truly believe Every Drop Counts. As a company, we embrace responsible behaviors that put the good of our constituents above all else. We promote the health and wellness benefits of water, coffee and tea and give back to the communities we serve. By sourcing and processing responsibly, we protect the planet we inhabit. All of this matters to you, to us and our future.
Environmental sustainability is a daily commitment that promises a better tomorrow. We continually seek ways to deliver on our promise to protect the planet we all call home. After all, that's a promise worth keeping.
We seek to source all of our bottled waters responsibly. Our water sources are carefully selected and closely monitored to ensure consistent quality and sustainable yield. And, we align our company with brands that do the same.
We reduce environmental impact by using less. Over the last 10 years, we have reduced the amount of plastic in our U.S.- and Canada-branded 0.5-liter bottles by more than 50% and the caps by 25%. All packaging is 100% recyclable, including the bottles, caps and outerwrap.* Plus, our U.S.-branded 1- and 2.5-gallon bottles are shipped in reusable, recyclable corrugated boxes. To reduce total weight and waste, we've made our plastic cups lighter, too.
Our U.S. and Canada-branded 3 gallon (11.3 liter) and 5 gallon (18.9 liter) water bottles are reused up to 50 times. At the end of their usable life, the bottles are recycled and used to make new products. This closed-loop recycling system allows us to reduce our carbon footprint by assuring that bottles do not go to landfills.
We are currently working on multiple fronts to improve transport efficiency. Recent vehicle purchases promise a 40% increase in fuel productivity. To reduce delivery mileage, our representatives use smartphones to optimize their routes. When considering new water sources, we search for suitable locations near existing bottling plants. We are also developing specialized load/unload procedures and reducing transport distances from springs to bottling plants.
*Recycling facilities may not be available in your community.
We feel a strong sense of commitment to local communities. And, the world at large. Why? Because we're more than a socially responsible bottled water company, we are also part of the community.
Hydration is an important part of a healthy lifestyle. So, we provide sponsorship to local events such as 5Ks, volunteer events and more.
To fully defeat cancer, we believe in fighting the good fight. Our Athena® bottled water was Created for the Cause®, and we recently contributed $3 million on behalf of Athena to hospital oncology centers across the U.S. Also, DS Services® is proud to sponsor the American Cancer Society Hope Ball each year.
When disaster strikes, safe drinking water is a vitally important resource. That's where our regional brands provide needed relief. They regularly support humanitarian causes such as donating to relief efforts for communities ravaged by hurricanes.
Water is essential to our lives. That's exactly why we take so many steps to guarantee we produce quality bottled water that meets the highest safety standards. Furthermore, DS Services® is committed to full compliance with corporate financial regulations.
Is our bottled water good for you? You can rest assured. We use certified laboratories to ensure our bottled water products meet strict state and federal food and beverage quality and safety standards. DS Services® proudly includes accurate sourcing information on all labels. The bottled water brands manufactured by DS Services are regulated as a food by the FDA. DS Services works diligently to ensure that we meet or exceed the FDA standards for food safety and quality as required by the agency's Food Safety Modernization Act (FSMA).
At DS Services®, we strongly adhere to corporate compliance laws such as the Sarbanes-Oxley Act. We implement comprehensive internal controls and procedures to ensure responsibility and provide transparency.
We are committed to our customers and their needs. When they ask, we listen. For example, we recently introduced a new 1-gallon water bottle that's more lightweight because it uses less plastic.
Across our entire organization, we've implemented a number of measures to reduce paper usage. We've moved many customers to a digital billing and contract model. Also, we've adopted digital document storage practices.
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Long time readers of the blog will already know about my love for Stila cosmetics. Their 'convertible color' product is one of my all time faves. I was so happy when they made me my very own 'Stila' girl!
Those lovely people at Stila are offering one lucky Ring My Bell reader the chance to win this basket crammed with Stila goodies.
This giveaway is now closed and the winner has been notified.


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The cat-letes pounce into week 6 of the FFL season! This week the Hallmark Movies & Mysteries Mountain Lions take on the Hallmark Channel Hearties. Plus, the Good Witch Wildcats take on the Northpole Panthers.
Cat Center - Week 8 - Games of The Week
The Northshore Bengals make a last minute pounce in their bid to make the playoffs. Plus, things get off to a stormy start when the Home &…
Cat Center - Week 6 - FFL Season Preview…
John and Mary take a look at some of the new elements that will give cat-letes oppawtunity for higher scores and su-purr-ior plays!
Cat Center - Week 10 - The 2017 Season R…
Mary and John take a look at the teams and cat-letes vying to pounce their way to the Kitten Bowl IV Championship.
Cat Center – Week 9 – This Week's Top Defensive…
Relive all the purr-illiant stops and adorapawl saves as Mary and John recap this week's top defensive plays.
Cat Center - Week 4 - The 2017 FFL Draft…
Feline Football League Commissioner Boomer Esiason announces the picks of the litter in the 2017 FFL Draft.
Cat Center - Week 7 - The FFL's Fumbles,…
Mary and John take a look at some of the league's most un-fur-getable fumbles, flops and fails.
Cat Center - Week 5 - Boomer's QB Training…
Human football legend & FFL Commissioner, Boomer Esiason holds his annual training camp for the FFL's top quatercats.
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Tony Slo-Mo, Pork Chop and other top prospects show off their skills for the league coaches.
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FFL Commissioner Boomer Esiason recognizes the newest members of the league's Hall of Fame. Among this year's honorees is Mr. Slippers, the Kitten…
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John and Mary take a look at which cat-letes are making waves in the run up to Kitten Bowl IV.
Cat Center - 2016 Week 6
Kitten Bowl III is upon us and the playoffs featured some Purr-nominal matchups, watch the highlights.
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This week the 2016 Feline Football League was filled with impressive plays and cute cuddles
Cat Center 2016 - Week 4 FFL "Oops" Plays…
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This week the Home & Family Felines pounce onto the Last Hope Lions. Plus Boomers Bobcats look to claw their way to victory over the North…
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Commissioner Boomer Esiason announces the latest inductees into the Feline Football League Hall of Fame.
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Julie Taymor, the ousted director and creative force behind "Spider-Man: Turn Off the Dark," mused Saturday on the production troubles the Broadway musical has faced.
She told an audience of industry insiders about her artistic vision for the show, whose music U2's Bono and the Edge wrote, and about what she thinks played a role in its problems.
Not least among those, she said: The decision to open the show on Broadway instead of in another city, the constant scrutiny the celebrity-studded production faced and the power of social media.
U.S. & World
"It's incredibly difficult to be under a shot-glass and a microscope like that," she said of the heavy publicity and interminable lead-up to the show's opening earlier this week. "Twitter, Facebook, blogging just trumps you."
Taymor criticized the use of focus groups to help make major artistic decisions on the show, too.
"It's very scary if people are going more towards that, to have audiences tell you how to make a show," she said. "Shakespeare would have been appalled."
The show had clocked a record number of previews, a string of actor injuries from elaborate aerial work and costs of $65 million by the time it opened. Most critics panned it.
Taymor was still excited about her original ideas for the show.
One of those ideas was the inclusion of the mythological Arachne character, which critics questioned but Taymor insists was central to the "Spider-Man" comic books.
Another was the idea of using a nontraditional venue—like a circus tent on top of New York's Madison Square Garden.
Regardless, Taymor was enthusiastic about the project from the beginning, and not just because of the collaborators involved.
"Pieces that attract me have to do with outsiders," she said. Plus, "Peter Parker had everything to sing about—he had yearning, he had exuberance, he had unrequited love."
Selected reading: Los Angeles Times, Variety, New York Times


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Just the facts: A vegan diet is safe, healthy for infants
Critics have misused case of baby's death to question food
It was a horrific crime. Last month in Atlanta, two parents were convicted of intentionally starving their 6-week-old child to death. As part of their defense, the parents of Crown Shakur claimed that they are vegan, meaning that they do not consume meat, dairy or other animal products. Their conviction has brought international attention to vegan child rearing.
As a nutritionist who testified as an expert witness for the prosecution in the trial, I want to clear up some disturbing misunderstandings about the case. Vegan diets are not only safe for babies; they're healthier than ones based on animal products.
Unfortunately, not everyone talking about Crown's death is getting the facts right. Some are even misusing the tragic and confusing case to question the ethics and adequacy of vegan nutrition during pregnancy, lactation, infancy and childhood.
Yet one thing about Crown's death is very clear. He was not killed by a vegan diet. As the autopsy report stated, Crown died of complications of starvation. I was in the courtroom when the judge and jury were shown photographs of Crown right after he was pronounced dead on arrival at the hospital. The infant was literally skin and bones. His parents had fed him the wrong food for an infant — soymilk and apple juice. But the real problem was that he was not given enough food of any sort.
The other reason Crown died was that his parents did not seek medical care or even advice from a relative when it was clearly warranted. Astonishingly, the father stated under oath that he didn't know anything was wrong with Crown until right before he and the infant's mother drove him to the hospital. That was the child's first visit to any kind of health care practitioner.
Parents have a legal and moral responsibility to protect their children and keep them well-fed. And doctors and nutritionists agree that the best food for infants is mother's breast milk. The only viable alternative for the first six months of life is infant formula. Many nutrition experts recommend soy-based formulas, which are plant-based.
Interestingly, the breast milk of vegan mothers has been shown to contain significantly lower levels of environmental contaminants, such as pesticides, dioxins and bovine growth hormone, than the breast milk of meat-eating mothers.
First weaning foods, which should generally be introduced around six months of life, are nearly always foods from plant sources — mashed cooked vegetables, mashed fruit or rice-cereal thinned with breast milk or formula if need be.
A few months later, more protein-dense foods can be offered. Good choices include mashed beans, lentils and peas. According to the American Academy of Pediatrics, cow's milk is not recommended at all during the first year or so of life. Its consumption increases the risk of diabetes.
According to the American Dietetics Association, there is no need to introduce any meats, eggs or dairy products into an infant, toddler or child's diet. Well-planned vegan and vegetarian diets not only provide all the nutrients necessary to support growth, they also promote good health in childhood and start disease prevention early.
Just think about the advantages of raising a child on a diet rich in fruits, vegetables, grains and legumes. Limiting or avoiding consumption of fish sticks and tuna sandwiches reduces mercury consumption and the resulting risk of cognitive and behavioral problems. Choosing nondairy milks such as rice, soy or oat milk significantly lowers consumption of saturated fat and growth hormones given to cows to increase milk production. Substituting vegan sausage for bacon or pork sausage increases healthy fiber and sidesteps fattening and artery-clogging animal fats.
That all sounds pretty darn responsible to me.
How else can we responsibly promote the health of children?
We can embrace the efforts of parents who are finding creative ways to provide healthy, nutrient-rich foods to their children. We can support government policies that limit foods from animal sources and promote the consumption of whole or less processed foods, especially fruits, vegetables, grains and legumes. And we can demand that our medical system provide high-quality care to everyone, including people choosing a vegan lifestyle.
Lanou is a senior nutrition scientist for the Physicians Committee for Responsible Medicine and an assistant professor of health and wellness at the University of North Carolina-Asheville. She is also the author of "Healthy Eating for Life for Children."


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Black 2017 Ford F-150 Lariat 4WD 10-Speed Automatic EcoBoost 3.5L V6 GTDi DOHC 24V Twin Turbocharged ABS brakes, Compass, Electronic Stability Control, Front dual zone A/C, Heated door mirrors, Heated front seats, Illuminated entry, Low tire pressure warning, Remote keyless entry, Traction control.
Odometer is 5050 miles below market average!
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Our customers tell us the most unpleasant aspect of buying an used vehicle is negotiating the price. With that in mind, we've decided to give everyone our best price right up front. We have our best price in every vehicle at all times. We have priced our vehicles at the true best price to assure the integrity and fairness of your car buying experience. This is accomplished through weekly market comparison surveys. One price, the same price, every day, for all customers. In other words, we price the car ... not the customer. We're in Minot ND, also serving Bismarck, Williston, Dickinson, Devils Lake, and Fargo.
When you visit Minot Chrysler Center, you can put your guard down and relax because we offer no-haggle pricing. Customers appreciate the fact that they don't have to argue with salespeople and can instead focus their time and energy on finding the perfect automobile. We have the largest selection in the region at the best prices, which means our customers don't have to haggle. The prices are already impressively low on both new and pre-owned vehicles. We also offer specials and financing to customers, making it easier than ever to get behind the wheel of your dream car.
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While your warranty is as robust as your Land Rover, it doesn't cover all items, such as those subject to adjustment or replacement during normal service or maintenance operations. Likewise, it won't cover repair or replacement required as a direct result of:
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Simon Basketter reports:
The anti-union laws are being extended by default and we are moving towards a situation where it will be virtually impossible to organise legal strikes.
At the beginning of the month the Court of Appeal ruled in a case that has significant consequences for every worker.
Judges ruled in favour of Metrobus, which had secured a legal injunction against a planned strike by Unite members in October last year. The union called off the strike in response.
This ruling had a knock-on effect on another group of workers last week.
Unite union officials called off a planned strike by bus drivers at First in South Yorkshire—not because there was any challenge to their own ballot but purely on the basis of this Court of Appeal ruling.
The judgement in favour of the employer can be referred to by judges in future cases. It sets a precedent that will make it more difficult for workers to take legal strike action.
One of the reasons the company won the injunction was because a judge found that the union had not detailed with sufficient precision the occupational grades of those taking action.
The same manoeuvre has recently been used against postal and tube workers.
The anti-union laws were designed to hamper unions' ability to resist, and to give union leaders a way of persuading their members not to strike.
All these laws should go. But instead of being repealed, they are being interpreted ever more harshly. The laws detail a thicket of obstacles that the unions have to navigate to avoid being sued during a strike.
One clause says that unions have to give the employers a list of workers who are going on strike and their workplaces.
Unions must also sort workers into their occupational categories. Such requirements are ideal for employers who want to use technicalities to halt strikes.
The Metrobus appeal case shows how these laws work.
The union argued, "Unite takes the view that the grounds on which the judge decided to grant the injunction constitute a serious impediment on its ability and that of any other trade union to call a strike."
In response Lord Justice Maurice Kay wrote, "The right to strike has never been much more than a slogan or legal metaphor."
There were two main elements to the court's decision.
Firstly, although the strike ballot had closed at noon on 1 September, Unite informed Metrobus bosses of the outcome almost 48 hours later.
In part this was due to a mix-up between Unite and Electoral Reform Services involving a missing fax.
But the court ruled that the time taken to inform the employer was too long.
The judgement reads, "Sec 231 imposes on the union a free-standing obligation to notify the employer of the outcome of the ballot as soon as reasonably practicable; that obligation must be fulfilled, regardless of whether strike action is or is not voted for."
And importantly, "Notice of strike action can only ever come after notice of the ballot result to the employer."
Secondly, the court ruled that the union did not properly explain how it arrived at its membership figures for how many bus drivers would be called out from which depots.
The three Court of Appeal judges disagreed about how the legislation applied, but they still ruled that insufficient explanation was given.
The judgement read, "Information about the numbers of employees balloted—what categories they fall into in terms of what job they do, where they work, etc, for union members who may or may not pay their union dues by deduction from salary (whereby the employer can know they are union members) – is provided to the employer, and such information must also include full explanations of how such figures are reached. The figures must also be accurate."
In effect, legal ballots become almost impossible to organise. Working out all the grades of construction workers or local government workers, for instance, would be completely unfeasible.
The only point on which the majority in the court disagreed with the original injunction was over the importance of a typing error—766 instead of 776. It ruled that this was trivial.
Furthermore, the court also ruled that the anti-union laws are compatible with the article 11 of the European Convention on Human Rights on the right to join a trade union.
When Labour was elected in 1997 it had a policy of repealing the anti-union laws. But 12 years later it is sitting on its hands while the laws are applied ever more stringently against workers.
The anti-union laws fly in the face of the democratic decisions of thousands of workers. Unless the laws are challenged, no union could survive the level of detailed scrutiny now imposed on ballots.
But a recent spate of unofficial walkouts and occupations has shown that anti-union laws are powerless if workers defy them.
The only way to win is for unions to refuse to back down in the face of injunctions and threats and strike regardless.
The right to withdraw labour by striking is the most fundamental power that workers have. We must fight urgently to defend that right.


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Antonio Fernandez, MD
Born in Havana, Cuba, Dr. Fernandez completed his graduate studies at the Instituto Superior de Ciencias Medicas de La Habana, University of Havana, graduating as a Doctor in Medicine in 1979. After practicing general medicine, he completed his residency in neurosurgery (1981-1984) at the Instituto de Neurologia y Neurocirugia and Hospital General Calixto Garcia in Havana, Cuba. Since his arrival to the USA in 1992, Dr. Fernandez has taught in different undergraduate and graduate programs at Barry University and Nova Southeastern University.
A full time faculty at Barry University since 1997, Dr. Fernandez joined the Barry Anesthesiology faculty in 1998. He teaches Pathophysiology I, Pathophysiology II, and Pathophysiology III.


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Service in a pinch: Butler homers off bench for win
KANSAS CITY -- Benched. Left out. Stashed away. That was Billy Butler.
Until the eighth inning, that is. Butler came off the bench and blasted a two-run pinch-hit homer for a 6-4 victory over the Indians on Friday night, delighting a hometown crowd of 33,460.
Butler, once Kansas City's right-handed hitting machine, has had such a tough season that he was dropped from the lineup for the second time this week.
"It's my job to prove I belong in there," Butler said.
This will help -- a 422-foot home run off John Axford that sailed deep to left field and provided the Royals with their fourth straight victory.
The score was 4-4 and Salvador Perez was on base with a single. There were two out, and Butler was sent to bat for the left-handed Raul Ibanez. The Indians countered by bringing in a right-hander, Axford.
Butler busted Axford's second pitch.
"Axford's got a good fastball, and I got 1-0. Coming off the bench, it's hard to lay off that first-pitch slider. You're looking for a fastball," Butler said. "I was seeing it pretty good -- some days you do as a pinch-hitter, some days you don't. It's really weird. It's the toughest thing in sports to do."
Axford also gave up the game-winning hit in the Royals' 14-inning, 2-1 win on Thursday night.
"It was just a bad pitch, really. I just let it stay out over the plate a little too high up. It was supposed to be low and away and didn't end up there, so it ended up in the seats," Axford said.
This was only Butler's fourth homer all season and, uncharacteristically, he took a few extra moments to follow its flight.
"It's one of those things, when you hit them, you don't feel anything because you hit it so good. I definitely did not feel anything on that one," he said. "You've got a lot of emotion going through there, a lot of excitement. I knew when I hit it, I gave us the lead, and we had three outs to go."
Aaron Crow got those three outs in the ninth, surviving a leadoff double by Yan Gomes. Closer Greg Holland was held out because he'd pitched three games in a row.
"Just to be in that situation is a lot of fun, and it's just something, as a pitcher, you want to be in a lot," Crow said.
Butler's home run was the fifth of the game. Perez and Mike Moustakas hit successive homers off Indians starter Josh Tomlin in the second inning for the Royals' first back-to-back blasts since the same two batters connected on April 23 at Cleveland, also in the second inning.
Carlos Santana belted two homers off starter Yordano Ventura, accounting for the Tribe's first three runs. Cleveland's score-tying fourth run came on an error and a pop-fly mixup in the seventh.
Gomes reached base on Moustakas' throwing error and later scored from third on a sacrifice fly in shallow right. The problem was that second baseman Omar Infante and right fielder Lorenzo Cain were both chasing the ball and then shied away, forcing Cain to make a diving catch. That gave Gomes time to tag up and score.
"That's a tough play, man," manager Ned Yost said. "That's kind of right in the middle of both of them."
But in the long run, it didn't matter, because one inning later, Butler took care of things and earned endorsements from his teammates.
"Billy's one of those guys that was born to hit, and he's always going to hit, and you never count guys like that out," Ibanez said. "You know that eventually he's going to get hot and do what he's capable of doing what he normally does."
Perez, who had three hits himself, chimed in as well.
"Billy's a great hitter. For me, Billy's the best hitter on the team," Perez said. "He's maybe had a little struggle this year, but that's going to happen to anybody. I feel so happy that he got the big homer."
The clutch blast prompted memories of Butler's other pinch-hit homer -- on June 17, 2012, in an Interleague game at St. Louis. The Royals were one pitch away from defeat when Butler connected off Jason Motte for a 2-2 tie in the ninth inning of a game the Royals would win, 5-3, in the 15th.
"That one I'll never forget. This one hasn't quite soaked in yet. When you hit one against the Cardinals in the I-70 Series, it's got a lot of emotion, it's got a lot of tradition," Butler said. "I'm sure this one will overtake it, because it's the most recent. That was a big one, both of them are big. In those situations, you never forget them."
Despite the recent benchings, Yost noted that Butler's attitude has remained good, and Butler insisted that he understood his manager's actions.
"He's got a job to do, putting the lineup out there," Butler said. "As of late, the production is definitely not there. Over my whole career, it's there, but this game's about what you've done for me lately."
Lately? As of this moment, quite a bit indeed.


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Hi Donna,
I thought you'd like to see the article about you and the inn, published on BellaOnline (17 million verified monthly viewers) – I think you can tell we liked it!
Luxury Travel Site
Barbara Radcliffe Rogers
Intel Editor, Global Traveler Magazine
BellaOnline's Luxury Travel Editor
Warm Hospitality at Maine's Admiral Peary Inn
Snow was falling heavily, covering Route 302 and the world around it in white as we crossed the state line from Conway, New Hampshire, into Fryburg. Only a few yards off the main road, we found the inn, a rambling house whose history is hinted at by its name. It was once the home of Arctic explorer Robert Peary, who led the first expedition to reach the North Pole, in 1909.
As Donna, the lively and good humored new owner, showed us to our rooms, 12-year-old Mary was enchanted by the secret passageway that connected hers with ours. Although hers was reached from the staircase ascending from the large comfortable common room and ours from another set of stairs in the oldest section of the house, a gentle push on some recessed shelves in her bathroom revealed it to be a small door leading into an under-the-eves closet. At the other end was a door that opened into our room.
That wasn't all. The slanted ceiling in her room was covered in a scene from Tuscany, complete with a stone castle, so from her bed instead of looking out at a snow-covered New England village, as we did, she looked out on a sun-drenched Italian landscape.
With a nod to Peary's wanderlust, and to her own travels during a career in the Air Force, Donna has decorated each room as a bit of somewhere else. Mary's was Tuscany, ours Panama. On our walls were some of the best examples of molas I have seen, one an incredibly fine piece from the height of this needlework form, another a wonderful example of how the San Blas islanders incorporated modern design themes into their age-old handwork.
The most dramatic room holds her collection of Japanese woodcuts, and above its bed – an elevated futon decorated in red cushions – hangs a pair of dramatic two-tiered red lamps. Savannah wildlife photos and a bold tapestry rug from Africa gave a safari feel to another. Other guests were in Paris, so we didn't see that one.
The exceptional molas and secret passageway were not the only attractions of our room. A desk was built into a dormer, with a handy outlet for electronics (there is wifi throughout the building) and light that window and two on the opposite wall made the room bright and cheerful. A complete suite of Olivia amenities were on the top shelf in the bathroom, and other shelves were filled with plentiful extra towels. A thoughtful extra was a cheeseboard with corkscrew, bottle opener and a cheese spreader on our bureau.
Downstairs, adjacent to the big common room was a pool table, so Mary taught me the finer points of the game, then beat me at it (but not by much), before we walked up the street through the still-swirling snow to Oxford House Inn, an excellent restaurant recommended to us by our friend Hilary at Maine Travel Maven.
After a breakfast of home-made granola with berries and a delicious hash-brown-and-sausage quiche, my two companions went off to ski in the 9 inches of new now at nearby Cranmore Mountain in North Conway. I settled into the comfy wing chair in our room, with my feet propped on the fender of a Franklin stove. I'm sitting out the rest of this ski season with a knee injury, but that doesn't keep me from having a good time on our annual ski vacation.
Donna tempted me with a bowl of her chili for lunch – way above and beyond the expected at a B&B, and a little guest kitchen held a Kurig coffee maker, microwave and refrigerator stocked with complimentary soft drinks. In the afternoon, I retired to the library, a gem of a room on the front of the old house, with walls in a muted dark blue and one entire wall of bookshelves filled with everything from mystery and romance to literature and world travel. Maybe after my leisurely day and Mary's long day on the mountain, I'll have enough advantage to win at tonight's pool game.
Admiral Peary Inn is at 27 Elm Street, in Fryeburg, Maine 04037; tel (207) 935-1269.


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Hey there. Just a few things on my mind.
I picked up a nail. Which led me to a tire store where I was looking for a patch. Well, if you pick up a nail and it's in a certain place where your tire is worn they can't patch it very well. Which means I gotta get a tire. Cause it's all wheel drive - I gotta get two rear tires. Since Daddy said you always have to buy 4 tires at a time looks like I'll be riding on some tread. Which comes in handy on these high speed rolly polly slippy slidey roads in Nashville.
March is trying to kick up some Spring around here but we've had a serious cold snap. Down to 20 degrees at night -
Shut your mouth.
No, Really. It's some crazy cold for those of us with thin skin. My sister calls me a lizard cause I used to lie in the sun on the beach for hours upon hours. It just charged my battery. I need the sun, need a rock and I'm relaxed.
Closest thing to it - building a fire in the fireplace and lying on the floor rotating myself. Big dog doesn't care for the heat but if I"m on the floor and he's laying next to me it's the best sleep he ever gets. He's got an old dog snore and I swear I could ride that snore to heaven. Its good to know that your company means so much. Just being nearby. You can't ask for more than that. Well you can - but why?
Got some new friends reading Saints, and Messenger, Mercy, and The Gin Girl and asking me why in the world I don't write music because I sure write novels like I write music. I said - okay. I'll write some music. So I have. It's Nashville after all. Seems like it by be a sin not to. At least around here.
Spring's setting in no matter how the cold turns. Summer is coming on. Porch time. Long nights. Fireflies. Shooting stars. In light of that, in spite of everything, it's still a good time to be alive.
What's happening in your neck of the world?
Thanks so much for reading, liking and sharing with friends.
July 2020


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Laboratory Protocols
Laboratory Protocols are information briefs about standard laboratory tests and include the procedural steps as well as the purpose, theory, history, safety considerations, tips and comments, and references. The protocols are geared for microbiology educators at all levels and assume a basic understanding of general microbiology. All protocols are free, original, open access, and peer-reviewed by the microbiology educator community. Protocols were published between 2005 and 2015.
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All About Neutrinos
What is this thing, anyways?
Neutrinos are subatomic particles produced by the decay of radioactive elements and are elementary particles that lack an electric charge, or, as F. Reines would say, "...the most tiny quantity of reality ever imagined by a human being".
Of all high-energy particles, only weakly interacting neutrinos can directly convey astronomical information from the edge of the universe - and from deep inside the most cataclysmic high-energy processes and as far as we know, there are three different types of neutrinos, each type relating to a charged particle as shown in the following table:
|Charged Partner
|electron (e)
|muon (µ)
|tau (τ)
Copiously produced in high-energy collisions, travelling essentially at the speed of light, and unaffected by magnetic fields, neutrinos meet the basic requirements for astronomy. Their unique advantage arises from a fundamental property: they are affected only by the weakest of nature's forces (but for gravity) and are therefore essentially unabsorbed as they travel cosmological distances between their origin and us.
Where are they coming from?
From what we know today, a majority of the neutrinos floating around were born around 15 billions years ago, soon after the birth of the universe. Since this time, the universe has continuously expanded and cooled, and neutrinos have just kept on going. Theoretically, there are now so many neutrinos that they constitute a cosmic background radiation whose temperature is 1.9 degree Kelvin (-271.2 degree Celsius). Other neutrinos are constantly being produced from nuclear power stations, particle accelerators, nuclear bombs, general atmospheric phenomenae, and during the births, collisions, and deaths of stars, particularly the explosions of supernovae.
A little bit of history
The neutrino was first postulated in December, 1930 by Wolfgang Pauli to explain the energy spectrum of beta decays, the decay of a neutron into a proton and an electron. Pauli theorized that an undetected particle was carrying away the observed difference between the energy and angular momentum of the initial and final particles. Because of their "ghostly" properties, the first experimental detection of neutrinos had to wait until about 25 years after they were first discussed. In 1956 Clyde Cowan, Frederick Reines, F. B. Harrison, H. W. Kruse, and A. D. McGuire published the article "Detection of the Free Neutrino: a Confirmation" in Science, a result that was rewarded with the 1995 Nobel Prize.
In 1962 Leon M. Lederman, Melvin Schwartz and Jack Steinberger showed that more than one type of neutrino exists by first detecting interactions of the muon neutrino. When a third type of lepton, the tau, was discovered in 1975 at the Stanford Linear Accelerator, it too was expected to have an associated neutrino. First evidence for this third neutrino type came from the observation of missing energy and momentum in tau decays analogous to the beta decay that had led to the discovery of the neutrino in the first place. The first detection of actual tau neutrino interactions was announced in summer of 2000 by the DONUT collaboration at Fermilab, making it the latest particle of the Standard Model to have been directly observed.
Just passing through!
It is the feeble interaction of neutrinos with matter that makes them uniquely valuable as astronomical messengers. Unlike photons or charged particles, neutrinos can emerge from deep inside their sources and travel across the universe without interference. They are not deflected by interstellar magnetic fields and are not absorbed by intervening matter. However, this same trait makes cosmic neutrinos extremely difficult to detect; immense instruments are required to find them in sufficient numbers to trace their origin.
Neutrinos can interact via the neutral current (involving the exchange of a Z boson) or charged current (involving the exchange of a W boson) weak interactions.
In a neutral current interaction, the neutrino leaves the detector after having transferred some of its energy and momentum to a target particle. All three neutrino flavors can participate regardless of the neutrino energy. However, no neutrino flavor information is left behind.
In a charged current interaction, the neutrino transforms into its partner lepton (electron, muon, or tau). However, if the neutrino does not have sufficient energy to create its heavier partner's mass, the charged current interaction is unavailable to it. Solar and reactor neutrinos have enough energy to create electrons. Most accelerator-based neutrino beams can also create muons, and a few can create taus. A detector which can distinguish among these leptons can reveal the flavor of the incident neutrino in a charged current interaction. Because the interaction involves the exchange of a charged boson, the target particle also changes character (e.g., neutron to proton).
Butterfly Nets For Ghosts
Many of the outstanding mysteries of astrophysics may be hidden from our sight at all wavelengths of the electromagnetic spectrum because of absorption by matter and radiation between us and the source. For example, the hot dense regions that form the central engines of stars and galaxies are opaque to photons. In other cases, such as supernova remnants, gamma ray bursters, and active galaxies, all of which may involve compact objects or black holes at their cores, the precise origin of the high-energy photons emerging from their surface regions is uncertain. Therefore, data obtained through a variety of observational windows - and especially through direct observations with neutrinos - may be of cardinal importance. There are methods which have been developed to observe the elusive neutrino:
- Reines and Cowan used two targets containing a solution of cadmium chloride in water. Two scintillation detectors were placed next to the cadmium targets. Antineutrino charged current interactions with the protons in the water produced positrons and neutrons. The resulting positron annihilations with electrons created photons with an energy of about 0.5 MeV. Pairs of photons in coincidence could be detected by the two scintillation detectors above and below the target. The neutrons were captured by cadmium nuclei resulting in gamma rays of about 8 MeV that were detected a few microseconds after the photons from a positron annihilation event. Today, the much larger KamLAND detector uses similar techniques and 53 Japanese nuclear power plants to study neutrino oscillation.
- Chlorine detectors consist of a tank filled with carbon tetrachloride. A neutrino converts a chlorine atom into one of argon via the charged current interaction. The fluid is periodically purged with helium gas which would remove the argon. The helium is then cooled to separate out the argon. A chlorine detector in the former Homestake Mine near Lead, South Dakota, containing 520 short tons (470 metric tons) of fluid, made the first measurement of the deficit of electron neutrinos from the sun (see solar neutrino problem). A similar detector design uses a gallium to germanium transformation which is sensitive to lower energy neutrinos. This latter method is nicknamed the "Alsace-Lorraine" technique because of the reaction sequence (gallium-germanium-gallium) involved. These chemical detection methods are useful only for counting neutrinos; no neutrino direction or energy information is available.
"Ring-imaging" detectors take advantage of the Cherenkov light produced by charged particles moving through a medium faster than the speed of light in that medium. In these detectors, a large volume of clear material (e.g., water or ice) is surrounded by light-sensitive photomultiplier tubes. A charged lepton produced with sufficient energy creates Cherenkov light which leaves a characteristic ring-like pattern of activity on the array of photomultiplier tubes. This pattern can be used to infer direction, energy, and (sometimes) flavor information about the incident neutrino.
- Two water-filled detectors of this type (Kamiokande and IMB) recorded the neutrino burst from supernova 1987a. The largest such detector is the water-filled Super-Kamiokande.
- IceCube and the AMANDA project take advantage of this method on a much larger scale by using ice instead of water; to facilitate this both are constructed in Antarctica at the south pole, the only place to find a chunk of ice big enough!
- The Sudbury Neutrino Observatory (SNO) uses heavy water. In addition to the neutrino interactions available in a regular water detector, the deuterium in the heavy water can be broken up by a neutrino. The resulting free neutron is subsequently captured, releasing a burst of gamma rays which are detected. All three neutrino flavors participate equally in this dissociation reaction.
- The MiniBooNE detector employs pure mineral oil as its detection medium. Mineral oil is a natural scintillator, so charged particles without sufficient energy to produce Cherenkov light can still produce scintillation light. This allows low energy muons and protons, invisible in water, to be detected.
- Tracking calorimeters such as the MINOS detectors use alternating planes of absorber material and detector material. The absorber planes provide detector mass while the detector planes provide the tracking information. Steel is a popular absorber choice, being relatively dense and inexpensive and having the advantage that it can be magnetised.
- The Nova proposal suggests the use of particle board as a cheap way of getting a large amount of less dense mass. The active detector is often liquid or plastic scintillator, read out with photomultiplier tubes, although various kinds of ionisation chambers have also been used. Tracking calorimeters are only useful for high energy (GeV range) neutrinos. At these energies, neutral current interactions appear as a shower of hadronic debris and charged current interactions are identified by the presence of the charged lepton's track (possibly alongside some form of hadronic debris.) A muon produced in a charged current interaction leaves a long penetrating track and is easy to spot. The length of this muon track and its curvature in the magnetic field provide energy and charge ( μ+ versus μ- ) information. An electron in the detector produces an electromagnetic shower which can be distinguished from hadronic showers if the granularity of the active detector is small compared to the physical extent of the shower. Tau leptons decay essentially immediately to either pions or another charged lepton, and can't be observed directly in this kind of detector. (To directly observe taus, one typically looks for a kink in tracks in photographic emulsion.)
- Most neutrino experiments must address the flux of cosmic rays that bombard the earth's surface. The higher energy (>50 MeV or so) neutrino experiments often cover or surround the primary detector with a "veto" detector which reveals when a cosmic ray passes into the primary detector, allowing the corresponding activity in the primary detector to be ignored ("vetoed"). For lower energy experiments, the cosmic rays are not directly the problem. Instead, the spallation neutrons and radioisotopes produced by the cosmic rays may mimic the desired physics signals. For these experiments, the solution is to locate the detector deep underground so that the earth above can reduce the cosmic ray rate to tolerable levels.


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So, lately it seems that I can't talk about anything else. So, why change. 🙂
Here's a video I did late last week with Nate Johnson of WRAL about the balloon launch that we did. This was recorded the day before we found our first balloon.
So, lately it seems that I can't talk about anything else. So, why change. 🙂
Here's a video I did late last week with Nate Johnson of WRAL about the balloon launch that we did. This was recorded the day before we found our first balloon.
We have gotten quite a bit more press coverage than I had anticipated. Here's a list of what I know of so far:
And, here's video from a segment on WRAL's 6pm news yesterday evening:
I'll have a more complete writeup later when I can slow down and wrap my head around things, but for the moment here's a quick update. Our first balloon lost tracking about about 20k feet. Not to be deterred, we quickly put together a second balloon from spare parts and sent it up. It landed a few hours later in Rocky Mount and we spent 4 hours getting it out of the tree where it landed about 65 feet off the ground! Once we did, it turned out to be well worth it as we found some great pictures!
Also, we ended up on the front page of the News and Observer today! Here's the article.
I just spoke briefly on the phone with Josh Shaffer from the Raleigh News and Observer newspaper. It looks like there will be an article about our balloon launch in tomorrow's paper. I don't think I'll have a chance to pick one up unless I can find one in the evening. If anyone local can grab one for me, I would greatly appreciate it.
I'll write more about this when I get a chance, but this Sunday morning, myself and a group of people will be launching a balloon to "near space" in an attempt to get a picture of black sky and the curvature of the earth. You can read the press release about it here: http://tinyurl.com/33wxxww
It's been a crazy month, but a lot of fun!
My son and I have enjoyed visiting the Duke Teaching Observatory quite a bit this past year. Through that, I learned that my friend Lisa has a very nice Dobsonian Telescope that she and her father had built. This lead me to this book which details how to build a modern Dobsonian.
Then Janell gave me a membership to TechShop for my birthday. In trying to figure out a project to tackle while using that membership I thought about building a small Dobsonian. I happened to mention this my friend Scott. Scott's in the process of moving right now and mentioned that he had a telescope that he bought in 1977 that needed a bit of repair. After a bit, he ended up giving it to me. (Thanks Scott!). The telescope in question is a Criterion RV-6. It is a Newtonian Reflector mounted on a German Equatorial Mount with a clock drive. At some point, the telescope fell over onto the finderscope and made a hole in the tube. In addition, the primary mirror was fairly dirty with insect droppings and the focuser was pretty jammed up.
But, in general, the telescope was in good shape. TechShop RDU still hadn't reopened yet and in investigating what it would take to restore the RV-6 I didn't think I would need any of the specialized tools available there so I decided to go ahead and start the restoration at home. The first step was to fix the hole in the tube.
I pulled out the mirrors, took off the focuser and pulled out the tube. I was very lucky in that the tube material at the hole was still there, it was just cracked and pushed up. I pushed what I could back together and threw on a bunch of epoxy gel over the hole. After it cured, I sanded down the area and then went ahead and sanded down the entire tube. This fixed the hole.
The next problem was the primary mirror. Using instructions in the book about building Dobsonian telescopes, I cleaned the mirror. It cleaned up well, but if you look at it from the back you can see light shining through in various spots. However, since this is a 33 year old mirror, that was not unexpected. At the moment though, it is good enough for the restoration to proceed. At some point, however, I will want to send the mirrors off to be recoated.
The next part to fix is the focuser. While it was on the telescope the original focuser could be moved with a HUGE amount of effort. After taking it off, however, it is even more jammed. This wouldn't be very conducive to using the telescope, so after reading about two separate RV-6 restorations that used a JMI RCF-Mini1 focuser as a replacement, I ordered one to replace the original focuser. It should be here sometime this week. Once it gets here I will need to make a few small modifications to the tube to make the new focuser fit (but not too much).
Once I get the focuser set up and working correctly, the telescope should work, however, the work will not be completely done. I will still need to paint the tube. The original RV-6 was painted white. While purists may not like it, I don't believe a white telescope is a good idea. White is very reflective and when you're trying to see faint bits of light in the sky the less reflective light you have around the better. Therefore, I plan to paint the tube blue. From a reflected light perspective, black would be better, but black would cause the tube to heat up quite a bit during the day. Blue will cause that too but not as much as black, and I like blue better than black, so there.
Once that is done, I'll need to set up a new finderscope. I'll have more on that later. I'll also need to see if any repair needs to be done on the clock drive. The most common repair for the clock drive that I've seen is replacement of the internal cork, but thankfully that seems to be an easy enough repair.
Hopefully, I will be done with the telescope repair within the next few weeks and I can start using the telescope. I'd love to see what I need to do to start taking pictures with it.


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This calculation will give you the ratio, in decibels, between two power values.
For example, you can calculate the difference in dB between to amplifiers with different power output specifications.
Enter any two values and press "Calculate" for the remaining value. Press "Reset" before performing each calculation.
Equation used to calculate the data:
dB = 10 * Log(Pout / Pin)


text:
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Lesson Plan
Textmasters: Shaking Up Textbook Reading in Science Classrooms
|6 – 8
|Lesson Plan Type
|Standard Lesson
|Estimated Time
|Seven 60-minute lessons
|Lesson Author
North Canton, Ohio
Textmasters was created to bring the collaborative learning environment of literature circles to content area reading with a science or social studies textbook. Students are placed in groups of four and given a schedule of the reading of the upcoming chapter. All students read the same section of the book but complete a role sheet to guide their perspective: Discussion Director, Summarizer, Vocabulary Enricher, and Webmaster. Each role was created with textbook structures and formatting in mind. Students meet together to share their roles. Meetings continue biweekly until the chapter is finished. Creative presentations serve as a review of the chapter content before groups are set up with a new reading schedule.
Wilfong, L.G. (2009). Textmasters: Bringing literature circles to textbook reading across the curriculum. Journal of Adolescent & Adult Literacy, 53(2), pp. 164171.
- Student scores on chapter tests went up 6% when comparing a traditional round of reading, answering questions, and study guide review versus Textmasters meetings and creative presentation review.
- Students enjoyed the collaborative nature of the strategy, reporting that they learned more from their peers than by merely reading the text and answering questions.
- The teacher involved with the pilot of the strategy stated that, after her initial organization of materials for students, she had more time to work with high-needs students.


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Our new £1m Innovate high street and retail project may have just started, but the research underpinning our successful bid for the £1m 'bringing big data to small users' project has been awarded a 'best in track' prize for retail at this year's Academy of Marketing Conference, held at Newcastle Business School.
The research identified new footfall signatures and town types the team had found in their preliminary analysis of footfall data, provided by Springboard, who are leading the new project. The findings were presented in a competitive paper "Radical Marketing and the UK High Street: Towards a New Typology of Towns" authored by Cathy Parker, Nikos Ntounis, Simon Quin and Ed Dargan.


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I am putting together a one-hour presentation aimed towards other software developers regarding a general introduction to User Experience, and I have a general idea on what I want to present. However, I thought it would be interesting to ask the UX community the same as well.
- What topics should one cover?
- What are some common questions/discussions that usually come up during these presentations?
- What would be your "Most Important Message" for the audience?


text:
I'm sure a lot of you spent time up at the cottage this long weekend, or some of you may be delving into beach reading as we speak...what I want to know is: What are you reading?
What have you read lately that you loved and would want to see as the Blogger bookclub series? What book do you want to read and need an excuse to pick up and chat about with other readers?
Let me know via comments some titles you want to see on the upcoming bookclub list!