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Joined: 16 Jun 2005
Posts: 19
Location: Lyon, France
Posted: Wed Jun 29, 2005 10:31 pm
Post subject: Carcassonne recommendations
My husband and I are planning a belated voyage de noces to Carcassonne and the surrounding area in August. Anyone have any recommendations of sights, restaurants, etc? TIA!
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Chicago Bear
Joined: 02 May 2005
Posts: 240
Location: Chicago
Posted: Thu Jun 30, 2005 9:34 pm
Post subject:
I've never been, but now that I've seen pictures of it on the internet, it looks like a terrific destination.
Here are their regional food and wine specialties: Cassoulet, foie gras, daube, magret et jambon de canard, vins AOC du Minervois, Corbières, Fitou ; Vins de Pays : Côteaux de la Cité, du Cabardès, Blanquette de Limoux, Carthagène, Muscat, Liqueur la Micheline, Eaux de Vie de Marc, Or-kina.
Now all you need is for someone to tell you the best places that serve it!
The goal is to fit it all in.
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Joined: 30 Sep 2004
Posts: 1855
Location: Ottawa, Ontario, Canada
Posted: Sat Jul 02, 2005 3:04 pm
Post subject:
Carcassonne! Stunning! A miracle really. It was slated for demolition sometime in the late 19th or early 20th century nut some visionary saw that it was one of the largest communities of medieval buildings extant in all of Europe so lobbied the government of the time to save it. A gift to all who get to see her. We were there a few years back so I can't give you any specifics of restaurants but do go to the main museum there! And cassoulet of course, even if it is August and cassoulet is best as a cold weather dish!
Vivant Linguae Mortuae!!
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Joined: 11 Mar 2005
Posts: 696
Location: israel
Posted: Sun Jul 03, 2005 9:38 pm
Post subject:
Hello bakerswife ( you're lucky if you can eat your husbands tasty creations, mine is a journalist so I have to swallow words,nor bakers goodies..)
Now about Carcassonne in August. Make sure you have air condition in your Hotel. Carcasonne, as David mentions, is a jewel. But a very very very very tiny jewel, so tiny that about two -three hours maximum, are sufficient. And that's by walking slowly ( because of the heat). Don't even think eating cassoulet in the touristic restaurants in the main ( tiny) square. They are horrible. There are some expensive restaurants too, I didn't try them so I don't know. Consult the Michelin or the gault Millau, but I presume there are better ones outside the overtouristic walled town of Carcasonne. As for the surroundings, not very much. Maybe Albi , the cathedral is ourstanding, the Toulouse Lautrec Museum too. BUt maybe the cool air of the neighbouring Pyrinees will be more suitable for the digestion of cassoulet, foie gras and magret de canard.
Happy anniversary!
No more war, more foie gars ( even in August)!
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Joined: 16 Jun 2005
Posts: 19
Location: Lyon, France
Posted: Mon Jul 04, 2005 3:59 am
Post subject:
simona, thanks so much for the info. We are planning on using Carcassonne as a base (and our hotel does have A/C and a pool), and we plan to do day trips to wineries, the seashore, and Toulouse. We have family near Toulouse also, and we might visit them as well. Your advice is very helpful, and I will look at the guides you mentioned.
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Joined: 30 Sep 2004
Posts: 1855
Location: Ottawa, Ontario, Canada
Posted: Mon Jul 04, 2005 4:39 pm
Post subject:
If you get a chance before you go, try to get hold of a copy of The Perfect Heresy by Stephen O'Shea. It is the most readable history of the Cathars I have run across and sheds much light on the cities and princes of Carcassonne and Toulouse-----------and it is just plain exciting to read!
Vivant Linguae Mortuae!!
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Joined: 16 Jul 2005
Posts: 5
Posted: Sat Jul 16, 2005 3:32 am
Post subject:
I visited Carcassonne and stayed at the Domaine d'Auriac
Beautiful hotel and one-star Michelin restaurant.
I also recommend reading The Perfect Heresy. With that, a visit to the awesome cathedral at Albi is in order. Just a truly fear-inspiring building, that indicates the power of the Church over the common man, built after the Cathar heresy was squashed.
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To be honest, what would really, truly shock—Lincoln getting shut out, or Anne Hathaway being denied—isn't going to happen.
Still, Thursday's nominations for the 85th Annual Academy Awards are bound to hold some surprises.
Five guesses as to what the unexpected Oscar developments will be:
No Directors Guild nod for Quentin Tarantino
1. Les Misérables Pulls in Most Nominations Since Chicago: Granted, this wouldn't be so much a shock as a by-product of the musical genre—i.e., Lincoln may be great and acclaimed and the film to beat, but it ain't going to pump up its numbers in Sound Mixing and Sound Editing. Still, if everything falls Les Mis' way, the film will raise eyebrows with a Chicago-tying and Lincoln-topping 13 noms for Best Picture, Best Director (Tom Hooper), Best Actor (Hugh Jackman), Best Supporting Actress (Hathaway), Adapted Screenplay, Production Design, Costume Design, Cinematography, Makeup and Hairstyling, Editing, Best Song ("Suddenly") and the aforementioned Sound Editing and Sound Mixing.
Check out Les Mis primer
2. Fewest Number of Best Picture Nominees Since 2009: Let's say Lincoln, Les Mis, Zero Dark Thirty, Argo, Life of Pi and Silver Linings Playbook are locks. That's six. Add in probably-maybe Amour (a surprise itself?). That's seven. Throw in possibly-could-be Django Unchained, and that's eight Best Picture contenders, one less than last year, two fewer than either the 2011 and 2010 awards seasons—and a reminder that the Academy isn't required to field a baseball team.
Kathryn Bigelow and Mark Boal stand their ground when it comes to Zero Dark Thirty
3. Christoph Waltz In, Leonardo DiCaprio Out: Oddsmakers tell you Leonardo DiCaprio has the better shot at a Best Supporting Actor nod. Your Oscar gut tells you Christoph Waltz, a onetime winner in the category, could be the one hearing his name called Thursday. Worth noting: Neither Django Unchained star rated a Screen Actors Guild Award nomination, so perhaps it should register as no surprise if both are shut out.
What are Les Mis' Oscar chances?
4. The Master Is Reborn: This Paul Thomas Anderson epic never seemed hotter than the weekend it opened, four long months ago. At this point, the film would shock if it managed nods for Best Picture, Best Actor (Joaquin Phoenix) and Best Director (Anderson) to go along with its seemingly assured slots in Best Supporting Actor (Philip Seymour Hoffman), Best Supporting Actress (Amy Adams) and Original Screenplay.
Bradley Cooper, Naomi Watts and more honored at Palm Springs Film Festival
5. Beasts of the Southern Wild Fizzles: It has a backstory that's as great as its potential—who doesn't want to see Quvenzhané Wallis become the youngest-ever Best Actress nominee? But neither Wallis nor the indie wonder plays big on the small screen (where screeners get watched), and may not come up as big as once expected.

subset: commoncrawl


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Jabulani Leffall's Bio
Jabulani LeffallI've mostly enjoyed my life and career until now. Stay tuned.
Experience? Journalist by trade, writer by choice, right and blood. Experience? Well, 35 years and counting.
Been to every habitable continent but Australia. Have worked in LA, New York, DC, London, Shanghai, and Hong Kong at several points in the sordid career. Have called New York, LA, Chicago, Richmond, VA, Washington D.C. and Baltimore, New Mexico and Kansas City, Mo. home at one point or another.
And I have been throwing darts and pretending to know about business, finance, technology or all three when writing as a journalist for nearly 15 years. Been a consumer -- both good and horribly bad -- for twice as long. Had money, lost money, earned money, blew money. Been frugal, been wasteful. Still growing -- financially, intellectually and emotionally. Not so much physically, kind of as tall as I'm going to get and as big as I'm going to get unless I stop exercising.
Jabulani Leffall, 35, is an award-winning journalist and writer who attended Journalism School at the University of Missouri. His work has appeared in the Financial Times of London, Dow Jones Marketwatch, The Baltimore Sun, Investor's Business Daily, Variety, CFO Magazine, Compliance Week, Redmond Magazine, Black Enterprise, Black Web 2.0, the Los Angeles Business Journal and the Los Angeles Daily News among other publications.
He was a George Washington Williams Fellow for the Independent Press Association where from 2002 to 2004 he studied the effects of subprime lending on poor communities. After what happened in 2007 and 2008, he feels vindicated as a journalist for having called what was going to happen but saddened as an investor for not capitalizing off the calamities of others.
What else? Oh yeah, he also contributed vital research to the 1998 book University of Missouri History Professor Robert E. Weems, which is titled "Desegregating the Dollar."
Additionally, he has appeared numerous times on ABC World News and CNN as a commentator of business and world affairs, again pretending to know what the heck he is talking about. Mr. Leffall is currently Associate Editor, then Assistant Managing Editor of FactSet Research Systems' News and Media group where he is in charge of collaborating with other financial journalists who make ambiguous forecasts as they try to make sense of this crazy world.
He is also still trying to get his Google link count game up, writing for beer and generic happy hour whiskey money by contributing articles periodically to numerous publications and media companies. Some are those mentioned above, while the guerilla and gorilla stuff can be found at TheSimon.com and of course, right here at Wisebread.
Currently he is the host of Central Standard, a general interest radio talk show on KCUR 89.3 FM, a super-regional National Public Radio member station based in Kansas City. The show reaches listeners in Missouri, Kansas, Iowa and Northern Arkansas. He interviews local, regional, national and international businessmen, artist, writers, bloggers, normal people and sometimes accused murderers and people who edit magazines about Ferrets. You can catch the show in Mongolia, Brussels, Toronto, Paris and the Gobi and Sahara Deserts if you have Internet access and listen to the show on KCUR.org or podcast the show.
Lastly for info on exactly where Mr. Leffall lives and who he lives with, never mind. He resides at all times in a four-cornered room where he stares at candles and his mind plays tricks on him. Read his articles and blogs and listen to his radio program please lest he go completely mad.
UNAUTHORIZED Auto-BIOGRAPHER who refers to himself in the third person.


text:
Athletes Who Spark the Most Fan Arguments
List Rules Only athletes who are among the most debated in sports.
A list of athletes who are passionately loved and hated by sports fans. These divisive, controversial sports stars inspire both love and bile from the fan community in equal measure. Is Allen Iverson among the greatest players of his day, or an arrogant ball hog? Does Tim Tebow keep pulling out these miraculous victories because of innate ability, or is he coasting off the skill and tenacity of his teammates? Is Barry Bonds a stoic hero, or the ultimate baseball villain?
These questions and more have divided sports fans and caused more bar room arguments, than any political decision in recent memory. And with good cause. This list collects the most argued-about and widely discussed figures from the world of sports. Vote for the players you love to hate (or hate to love), and if we've missed any athletes that make you bicker with your friends over beers, be sure to suggest them at the bottom of the page.Who are the most controversial athletes? Vote on the person you think fits that bill when ranking this list.


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change news
last update: 2007-07-02
This page is intented for the admins of this site (or anyone, who got the password somewhere ;) ). So, if you don't have the password and don't know, how to hack around the password-check (what shouldn't be to hard), sorry, there is nothing to do here for you.
MessageID: 148
MessageID: 148


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IYHA Board of Directors Meeting: July 16, 2009.
Called to order at 6:37 p.m. by President Kevin Bourassa
Board Members Present: Monica Crandall, Brent Eilefson, Theresa Spiering, Mike Nundahl, Kara Chamberlain, Nina Dojan, Beth Soberg, Tom Johnson
Board Members Absent: Chris Drews
Guests: Torri Johnson, Rick Laporte, Dale Aukee, Cindy Anderson, Cheryl Mason, Pat Schumer
Minutes: The minutes of the last Board meeting were read.
Tom Johnson moved to approve June meeting minutes as read. Theresa Spiering second. Passed without debate.
Board Roundtable:
President: New residency rule at issue for 2009-2010 season, need to review and discuss further the implications (St. John's kids, e.g., appear to be within MV association boundary. Similar issue with Valentine Hills). Working with boys coordinator and partial PCD committee on various fronts; general matters coming in and being delegated.
Vice President: Tourney committee meeting. Need tourney committee assistance, someone to step into role of tournament coordinator next year/going forward, need raffle leadership as well. Get your volunteer hours! Chuck a puck discussion, need better accountability for insurance purposes, will pool funds with tourney revenue to be divided between IYHA and MV. Implementing a cancellation policy for tourney teams—first time. Goal is more to keep teams in rather than penalize teams who need to pull out—perhaps team pulling out can find replacement.
Secretary: Discussed publishing agenda I week prior to board meeting. Minutes posted to website when approved. Email issues caused delay in last month's newsletter/minutes.
Treasurer: Profit and loss statement handed out and discussed. Discussed budgeting. Mite account resolution in process. Outstanding balances owed by families will be discussed by executive committee. Balance sheet discussion—new financial system implemented and there may be some growing pains until we get all numbers accounted for.
Boys Program Coordinator: Prepared statement. Should be able to field 3 teams and Squirts and Peewees, Bantams are in-between at present. If we can retain some kids at Bantam level, might get to 3 teams. Will talk to Jeff Martin about this. Tryout policy posted on website, will look for tryouts to take place week of 10/19. DPCD (Rick McKelvie) will be on-ice facilitator. Will bring in non-coach parents to participate as well. Confident they will get it right and in a way that shows impartiality and fairness that evaluators of all sports exhibit. IYHA Training Camp – this will be a 3 week period beginning 9/28 (approximately 9 hours of ice at each level) for each player. Aiming for more training/development rather than typical warm-ups. On-ice will be led by among DPCD, Jeff Martin, Tadd Tuomie. Also, will do approximately 4 hours of goalie only training as well as other time during the 9 hours. Coach selection underway, both within IYHA and posted outside IYHA. Pre-season ice requests have been forwarded to the ice coordinator. 2009-10 tournaments are being worked on by Mark Hentges (Squirts), Dan Marcouiller (Peewees), Rick Laporte (Bantams). Goal is to send entry checks by 7/31. Noted that IYHA should register all teams with the IYHA tourney at all levels, even if unknown what teams we will have. Torri will remove old tryout process from website.
Girls Program Coordinator: Will attend district coordinator meeting, met with MV re: U14, will coop with MV at U14 (to be hosted by MV); U10 coop, MV to host A team (Dist 2), IYHA host B team (Dist 1&2). Still subject to District approval. IYHA will have a U12 A and B team. U8 status-still waiting to hear from MV. Discussion around registering at age appropriate or grade appropriate level. Torri to come up with some solution for the online registration process.
Initiation Program Coordinator: T-shirts ordered and should be here by parades. Will sell wherever possible, for profit. Discussion around parade participation, booth tending, etc. Have identified dates/times for Learn to Skate and Come Skate With Us recruiting events: 8/29 at 12:50, 9/12 at 9:40, and 10/10 at 3:10 (all at SuperRink).
District Representative: No Report.
Ice Commissioner: Working on purchasing ice, Coliseum ice good, still waiting for ramsey and SR ice. Ice meeting will take place shortly.
Registration Coordinator: Online registration moving forward. Registration fee amounts to stay same and include training camp. $55 tryout fee. Online registration tentatively 8/10 - 9/15, with a walk up date TBD. Need to get the word out—currently nothing out there about how and when to register for hockey!
Equipment Manager: Socks ordered. Logos updated on 2009 initiation jerseys. New logo to go to Torri for posting on website.
Standing Reports:
Player and Coach Development Committee: Presented by Kevin Bourassa: last year, budgeted $13k, plus goalie coach at $5k, warmups $2500 ($20500 total budgeted). This year anticipate director or PCD will have 110 hrs on ice, bring in a goalie coach, other coaches up to an additional $6k with pre-approval of PCD Committee. Recommend to enter into contract similar to Tadd's to reflect up to 110 hrs at $100/hr, to include off-ice meetings, etc. Others on ice (goalie coaches, helpers) to be utilized at bill rates between $35-$100, not to exceed $6k (use of "others" to be agreed upon by PCD Committee). PCD job description is being tweaked, including monthly verbal report to Board. Will be posted on website when complete.
Kara Chamberlain moved to approve the execution of a contract with Rick McKelvie which contains terms that are in accordance with the parameters set forth by the PCD group. Theresa Spiering second. Passed without debate.
President to get info to press and Torri once contract finalized.
Lake Region: Theresa Spiering, meeting next week.
Fundraising Committee: Cookbooks, 500 ordered at $3.40. 5k run looking for volunteers. Pancake breakfast waitstaff must be peewees and older. Next Knight Out event will be at Acapulco: 11-8pm, August 4. Dunn Bros community giving program introduced, free to participate, IYHA gets 2.5%.
Mike Nundahl moved to approve promotion of Dunn Bros discount card during registration and at team packet handout. Theresa Spiering second. Passed without debate.
Potential Partnership Committee: No report, but request Girls Coordinator keep them in the loop during MV coop discussions.
Website Update: 10,000 puck club will be posted on website. New logo will be put on website. New tryout process to be left on website. Rundle fundraiser on website and in newsletter. Need 10U banner for Rink 4. Old logo will be used.
Kara Chamberlain moved to purchase a banner for the 10Us to celebrate their 08-09 district championship. Brent Eilefson second. Passed without debate.
Follow IYHA on Twitter.
New Business:
Waiver Policy: Kevin Bourassa presented. IYHA does not have a waiver policy and thus no guidance on waiver issues. Other associations have a policy, e.g., Washburn, no waiver unless no team opportunity, Southwest similar.
Brent Eilefson moved to adopt a no waiver policy for IYHA, said policy to be drafted by the Secretary and to be presented for approval to the Board at the next board meeting. Theresa Spiering second. Passed without debate.
Volunteer policy: Monica Crandall presented. Need volunteers at tourneys—problem because lots of hours are completed outside of tourney and as a result there is a lack of volunteers for tourney. The tourney raises over $30k, should be a primary volunteer focus since the return on each hour volunteered is huge.
Monica Crandall moved to require each family to devote a minimum of 9 tournament volunteer hours per skater, with a minimum family cap of 12 tournament hours for families with multiple skaters, with additional volunteer hours 2 hours per skater with a family cap of 4 hours, head coaches, first time families and board members exempted. Theresa Spiering second. Passed without debate.
Beth Soberg motion to adjourn at 9:33. Theresa Spiering second. Passed.
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The Food Trucks are Coming!Published on Tuesday, July 24, 2012
(/images/postimages/cl2011_bm0162.gif) Food trucks were first at DHV during Candlelight. Yes, the rumors are true! We are going to have Food Trucks here at DHV on a regular basis, beginning July 28. We are collaborating with a Cedars group that is serving as brokers, working as go-between for DHV and independent food trucks. As you have probably noticed, food trucks are the hottest new trend in the food business, and if you have been in the Arts District or at the Sigels Parking lot on lower Greenville, you've seen how popular they are. Our Cedars brokers have made arrangements with a pool of around 15 food trucks, all of whom are interested in participating in a new Cedars Food Park at DHV. A portion of the proceeds will benefit DHV. To start, we plan to h ..


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It's time for another Thriller Thursday article, a weekly prompting post suggested by members of Geneabloggers. This one is the story of the ill-fated lives of William and Sarah Bechtel of Philadelphia, Pennsylvania.
It was Saturday, April 1st 1848, and the city of Philadelphia, Pennsylvania, was still reeling from the horrific murder of Mrs. Rademacher, who had been stabbed twelve to fourteen times as she lay sleeping in her bed. Her husband, a book seller and homeopathic druggiest, was also severely cut and badly beaten in the attack. The perpetrator had recently been caught and the city was still very much a buzz with the latest developments in the case. And so to have another murder just a few weeks later was frightful and appalling…
Sarah Bechtel was about twenty-six years old back on April 1, 1848. She was a young wife and mother. She had given birth to several children, but only one was still living. Her husband, William Bechtel, was a boatsman and, in fact, on the day of the murder he had been down by the river arranging for an upcoming trip on the Schuylkill Canal.
Presumably the Bechtels were not wealthy. They lived in an apartment on Schuylkill and Thompson Streets in a section of the city known as the District of Penn. It was located near Girard College. On the day of the murder, Sarah and her upstairs neighbor had gone down to Fairmount Park to see if her husband was on board his boat. Thus she was not at home when he returned that evening with two friends.
Reportedly, William Bechtel had been drinking much of the day. Although it was said the couple often argued, William did not seem upset when Sarah first arrived back home that night. Shortly thereafter, however, he apparently snapped. In front of several witnesses, he grabbed her by the hair, jerked her head back and slit her throat with a jack-knife. Despite the fact that two physicians were summoned immediately, Sarah bled profusely and died about a half an hour after the attack.
William then apparently tried to commit suicide by slitting his own throat with the same knife, but that wound proved not to be serious and he was taken into custody. Once in jail it was reported that William became a "raving maniac." He had several periods in which he became quite violent and caused bodily harm to himself and those watching him. In mid-May he was moved from the county prison to the insane department of the Blockley Alms House.
William's murder trial occurred in the beginning of July in 1848. He was convicted of second degree murder and sentenced to the Eastern State Penitentiary for ten years. The conventional wisdom was that he committed the act in a fit of jealous rage fueled by the alcohol that he had consumed. There was some question as to whether or not he had any reason to suspect that his wife was in any way unfaithful, leaving open the possibility that the whole tragic situation was brought about by his own delusions.
As a postscript to this story, a death notice appeared in a Philadelphia newspaper for a William Bechtel, aged about 40, who died May 14, 1859. It could be the same William, but at this point I don't know for sure. I would love to hear from anyone who has further information on William or Sarah. I am still trying to determine if they are connected to my Bechtel line.
Note that the information contained in this posting comes from several newspaper articles that reported the event back in the spring and summer of 1848.


text: Most cellphone charms do nothing but sit there and be charming, but this one by Lava Lamp creator Mathmos actually serves a useful purpose: It blinks red (or blue, your choice) when you have a phone call coming in. Might be a good compromise between setting that phone on vibrate and possibly still irritating those around you, or missing all your calls. If you don't care for this retro-chic lava lamp replica, you can also get one shaped like a miniature light bulb. While we're not keen on having any kind of charm clanking around in our pockets along with a cellphone—likely scratching it up severely—this is one of the most useful cellphone charms yet. It's not even actually plugged into the cellphone, either, working by picking up the RF interference from the phone as receives a call. Not sure if that works every time, but it sounds like a good idea, one that might be worth the $12 plus shipping it would take to find out. [Technabob]


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The Average Molecular Weight [Ed:AMW] is currently an accepted orthodoxy within the Medicinal Chemistry community, a role reinforced by the recent popularity of things like the Rule of Five. To be sure, molecules with large molecular weights are not typically observed to be successful drugs.In all the rest of this note, I'd like to focus on the common scenario of selecting molecules for purchase or testing. I've often seen people apply AMW cutoffs or scalings to these processes. I'd like to show why this may be sub-optimal.First, I contend that the number of heavy atoms may be a much better proxy for "size" than AMW. Certainly, if you want to discriminate against heavier elements like Phosphorus, Sulphur, Chlorine, Bromine and Iodine, then by all means, use AMW. But with an AMW contribution of 126, a molecule with a single Iodine atom would be considered heaver/less desirable than the same molecule with a C6H9N2O substituent! Again, if you have good reasons for wanting to suppress these elements, AMW is a (very) good way of doing that.The case of the third row and beyond elements is fairly straightforward, but what happens within the organic group Carbon, Nitrogen and Oxygen. Does AMW vs natoms mean anything in there?Imagine we are selecting molecules for an assay and imposed an AMW cutoff of 180 – admittedly very low. We would then ignore Aspirin, with an AMW of 180.66, and instead we would test the "lighter" .But it gets worse. Imagine if the Lilly chemists looking for antidepressants had imposed an AMW cutoff of 308. That would have excluded Prozac, with an AMW of 309,Again, an AMW cutoff or bias could see us miss Zyprexa, AMW 312.4 and instead use the "lighter" molecule AMW 308.Or the even more lighter still Oxygen variant! Now, of course, no medicinal chemist faced with the choice between these molecules would choose the second one, that's obvious. Logp estimates would probably eliminate molecules that are all or mostly carbon atoms.But what the examples above show is that in any automated system that is basing decisions on AMW, there will be a systematic, albeit small, bias towards Carbon atoms and against Nitrogen and Oxygen atoms. Why? A single CH2 group contributes 14 to AMW, whereas an NH contributes 15, and a two connected Oxygen atom 16. As terminal groups, CH3 is 15, NH2 is 16 and OH is 17. A Pyridine Nitrogen contributes 14, but an aromatic Carbon contributes 13, t-butyl groups preferred over CF3. Carbon wins the low AMW contest every time.Now, how significant is this. Probably very small in most practical applications. I'd say that if you are setting up some kind of automated process, and you have equivalent access to AMW and the number of heavy atoms, use the number of heavy atoms in order to eliminate any small, pro-Carbon bias.
ConclusionWe see that automated procedures using AMW instead of natoms, will not only systematically suppress elements like P, S, Cl, Br and Iodine, but may also work to drive out N and O atoms as well!
This blog is meant to allow Fragment-based Drug Design Practitioners to get together and discuss NON-CONFIDENTIAL issues regarding fragments.
08 May 2012
Why NOT AMW
1 comment:
- Peter Kenny said...
I've always counted non-hydrogen atoms in preference to using molecular weight. Even before we got into fragment screening in the late 90s at Zeneca, we used a count of non-hydrogen atoms in analysis of high throughput screening output.
While it's fun to discuss the relative merits of different measures of molecular size, it's worth remembering that using a single set of cut offs is not the only way to do things. The Core and Layer approach that we've used and both Zeneca and AstraZeneca applies a series of progressively less restrictive cut offs.
We have a series of posts on fragment library design and these have been set up with 'next' links so people can read them in order. Here's the url of the first one:
- May 08, 2012 12:13 PM


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Khartoum, 26 May (SUNA)- The Minister for Social Security and Welfare, Mashayer Al Dawalab, has stressed that she welcomes any initiative from the civil society organizations that seek to fight poverty in eastern Sudan's most impoverished provinces in the state.
The Minister, who received a delegation from Eastern Sudan Talawait Charity, has welcomed the plan and strong partnership the charity has built for the implementation of some 16 project in the Red Sea and Kasala States that seek to help increase production and productivity and fight poverty in these areas.
The Minister has commended the lead role of the civil society organization in eastern Sudan region.
The meeting was briefed on the various interventions of the society, including efforts on attitude knowledge and practices in the area as well as efforts to change the food culture in the area.
The meeting also stressed the need to development agricultural and industrial initiatives with the civil society which will, in collaboration with partners, help alleviate poverty in the most impoverished communities in the area.
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What do you get when you take a relatively inexperienced director, a recovering train wreck of an actor and an under-the-radar superhero?
$585 million at the box office, glowing reviews and a career renaissance, that's what.
So what do you do for an encore?
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The day's top national and international news.
In 2008, when the first "Iron Man" film headed into theaters, few expected it to create the tidal wave of success which followed. Two years later, the hottest commodity on the block, Robert Downey Jr., is back as Iron Man/Tony Stark with some familiar faces and a few new playmates in tow, including director Jon Favreau with an expanded role as Stark's chauffeur Happy Hogan, Gwyneth Paltrow as his long-suffering assistant and love interest Pepper Potts, Don Cheadle, Terrence Howard's well publicized replacement, in the role of James Rhodes, Mickey Rourke taking up the resident baddy role of Ivan Vanko/Whiplash, Sam Rockwell as Justin Hammer and Scarlett Johansson as Black Widow.
Phew. Overwhelmed? Apparently so were the filmmakers.
Whether the problem was a lack of focus or your typical sophomore slump, "Iron Man 2" is the tired, rusty, older sibling of its gleaming predecessor.
It could be argued that the first "Iron Man" was so spectacular and unexpected, it's an impossible act to follow. Or, it might be that the production crumbled under its own hype. Whatever the reason, "Iron Man 2" fails to recreate the boisterous, combustible surge audiences were expecting.
Actor-turned-writer Justin Theroux, who co-wrote "Tropic Thunder," lost the fun this time around, filling the sequel with too many building montages and not enough of RDJ's riffing. Not that Downey Jr. can do any wrong, but you wonder if the best bits of his performance might have been left for the DVD special features. Meanwhile Rockwell, a chronically underrated actor, is the film's secret weapon, subtlety drawing humor from even his briefest moments on screen.
It's not that "Iron Man 2" is a bad movie, it's simply a "good enough" movie to kick off summer blockbuster season with a few cheap thrills. Fans were hoping for a lot more.


text:
MOVIE REVIEW- Dangle-ing participle: Silliness reigns in Reno 911!
The advantage of not belonging to the National Society of Film Critics is that one is permitted to enjoy a movie like Reno 911!: Miami without lamenting its lack of intellectual content.
As fans of Comedy Central's Reno-bound COPS spoof know, this is pure silliness. Not silliness with a brain, like Borat, nor silliness as a bad role model (unless you aspire to work for the Sheriff's Dept.), like Jackass.
Reno 911! is about a diverse group of imperfect people doing the best they can in an imperfect world, while having all their foibles photographed; and although they usually stay in their Nevada town where there's a limit to the damage they can do, for the big screen they take their show on the road. The crew of eight heads for Miami for "three days of fun in the sun" at the American Police Convention. (The dates are April 7-12, but in a movie like this, continuity errors may be intentional.)
They are four men and four women; four white, three black, one Hispanic; one gay, one lesbian and six presumed heterosexual, though from what we see most of their action is without partners.
Their leader is Lt. Jim Dangle (Thomas Lennon), who looks like a Village Person in shorter, tighter pants. Though desired by Deputy Trudy Wiegel (Kerri Kenney-Silver), he puts her off with statements like, "I'm playing for 'Visitor.'"
"I don't appreciate you insinuating that I'm some lesbian," says Deputy Cherisha Kimball (Mary Birdsong), as half a women's basketball team files out of her motel room. Deputy Raineesha Williams (Niecy Nash) has an eat-your-heart-out-Penelope Cruz fake booty that's visible from space, and Deputy Clementine Johnson (Wendi McLendon-Covey) spends most of the film investigating how she got a "tight tit tat" of an unidentified man one drunken evening. At least somebody's investigating something.
Rounding out the team are Deputies Travis Junior (Robert Ben Garant, who directed and co-wrote with Lennon and Kenney-Silver), S. Jones (Cedric Yarborough) and James Garcia (Carlos Alazraqui).
If there's not much space left for plot details, that's okay because there's not much plot. A mixup in credentials keeps our guys out of the convention center when it's quarantined by what sounds like an old "24" plot. With the local force trapped as well, it leaves Reno 911 to become Miami 911 and save the city from chaos– but who's going to save the city from them?
Along the way you find out why a chicken doesn't cross the road in Miami, and "Who brings a Weed Whacker on a boat?" The latter answer is Paul Rudd, doing his best bad Pacino-as-Scarface impression.
There are guests galore, from producer Danny DeVito to The Rock to Paul Reubens.
I could tell you I didn't laugh much at Reno 911!: Miami, but I'd risk being tried for perjury if they ever start a Law & Order: Reno.


text:
Herb-crusted haddock
Nutrition and extra info
- Healthy
Nutrition: per serving (unsmoked)
- kcal324
- fat14g
- saturates2g
- carbs21g
- sugars2g
- fibre1g
- protein30g
- salt0.87g
- 1 tbsp olive oil, plus extra
Olive oilol-iv oyl
Probably the most widely-used oil in cooking, olive oil is pressed from fresh olives. It's…
- 4 skinless unsmoked or smoked haddock fillets, approx 140g/5oz each
A white-fleshed salt water fish often compared with cod in flavour and texture. Found on the…
- 2 handfuls cherry tomatoes
A member of the nightshade family (along with aubergines, peppers and chillies), tomatoes are in…
- 3 tbsp mayonnaise
- 1 tsp garlic paste or 1 garlic clove, crushed
Part of the lily, or alium, family, of which onions are also a member, garlic is one of the most…
- 100g white breadcrumbs
- zest and juice 1 lemon
Oval in shape with a pronouced bulge on one end, lemons are one of the most versatile…
- 2 handfuls flat-leaf parsley, leaves roughly chopped
One of the most ubiquitous herbs in British cookery, parsley is also popular in European and…
Heat oven to 220C/fan 200C/gas 7. Lightly oil a large baking tray, then lay the haddock and tomatoes alongside each other. In a small bowl, mix the mayonnaise with the garlic paste or crushed garlic, then spread evenly over the fish.
In a separate bowl, toss together the breadcrumbs, lemon zest, juice and parsley, and season to taste. Top the fish with the breadcrumb mixture. Drizzle olive oil over the fish and tomatoes, and bake for 15 mins or until the fish flakes slightly when pressed and the crust is golden and crunchy.
Recipe Tip
Making it spicyStir ¼ tsp mild curry powder into the mayonnaise instead of the garlic, and serve the fish with rice.


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You can read the original article in The Windsor Star here.
From an outsider's perspective, Windsor comes off just fine to a pair of American graphic artists.
Sarah Baugh, 27, and Nicole Lavelle, 25, have turned wanderlust into art in Spirit of Windsor: An Outsider's Guide, produced in conjunction with Windsor's Broken City Lab arts collective.
The guide published in the form of a newspaper will be launched tonight at 6 p.m. at Broken City Lab's gallery, Civic Space, 411 Pelissier St.
The two were schooled in graphic design for newspapers and magazines at Portland State University, and put together a similar project for a small community in Utah.
That drew the attention of Broken City, which invited Baugh and Lavelle to turn the trick here.
"Our last project was to make a single edition newspaper about a community in Utah where we worked with high school students," said Baugh.
"We had no idea how this would turn out until we actually got here in Windsor."
The two were provided living space for a week in a small room at the back of the Broken City gallery. "It was a little tight for two," Baugh said, "but it was just for a week."
The artists roamed on foot through the downtown, stopping to eat where their fancies took them and taking in some of the more interesting sights.
"If we saw a rock that was painted yellow, we'd take a picture and make a note of it," Lavelle said.
"We had no idea where we were going until we got there."
They set out, notebook and cameras in hand, to record what they saw and did.
"We came with no previous knowledge of Windsor," said Lavelle. "Our cellphones wouldn't work so we had to rely on people who live here to find out how to get places."
Their guide to the city is something of a diary account of their walkabout. "Hopefully, this will have the dual purpose of providing people in Windsor with a different view of their city and offering some guidance to those who come here for the first time," Lavelle said.
Windsor turned out to be nothing like what they expected. They had stayed with some artist friends in Detroit a year ago and had an image of the small city across the Detroit River.
"When we first arrived one of the first places we went was the river," said Lavelle. "There's a river that separates Portland and people go there to have their pictures taken. Here, it took a while to realize that was another country across there."
The river is more than just a geo-political division between the two cities.
Said Lavelle: "I was struck by how close Windsor is to Detroit but how totally distinct the two communities are. Sure, it's an international border between them, but the two feel like completely different cities."
Baugh agreed. "It's so close and the ties are so strong. But, really, when you're here, you're here, and when you're there, you're there."
The guide will be provided free of charge to the shops and restaurants the two visited.
Baugh and Lavelle made their way across the northern U.S. in an old van in early January. "It was an adventure, that's for sure," Baugh said.
The vehicle is in the repair shop being overhauled for the return trip home to Portland. "We're hoping we don't run into any snow on the way back," said Baugh.
The road trip, she added, might end up providing source material for another project.


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Blexus Falconer wrote:Mirorog wrote:General AI problems is a big and complicated problem, however, all ally ships that are not randomly generated (ones that have unique names\captains, like The Flame Of Purity) just don't have an engagement range set. So it's not at AI problem, and I'm sure it's easier to fix.
Still: we can't patch the game with one 'easy' fix and make another one later with the harder ones. Fixing and adjusting the game cost resources and we need to be efficient in this case, by making a huge batch of fixes (plus testing them all at the same time).
On top of that, each patch need to be uploaded to Steam: we can't modify values on the fly like some online game. :s
Then, i'll wait


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JaoSming2KTV wrote:its fun on a bun
Pdub wrote:No, the game requires pixel shader 3. However, there was a mod that allowed you to run it. I doubt with your onboard graphics that it would be fast enough to play even on low settings.
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Augustana Senior Crowned Miss South Dakota USA
Augustana Senior Jessica Rowell was crowned Miss South Dakota USA on November 2, 2008 at the Brandon Valley Performing Arts Center in Brandon, SD.
Biology Faculty and Students Have Research Published
The Biology Department is having a banner year in 2008 when it comes to publications. Many of the published papers have been co-authored by Augustana students. In addition, there are several collaborators from other institutions.
Augustana Coach's Bond With Bo Ryan Helped Deliver Krabbenhoft to Badgers
The Capital Times: It would be an understatement to say that Augustana College men's basketball coach Tom Billeter is a friend of Bo Ryan's Wisconsin Badgers program.
Augustana Alumna Featured in Argus Leader
The special education department at Washington High School nominated Mary Ekeland to be featured, citing her ability to bring educators together.
Hearst Foundation Grants Additional Scholarship Support
The William Randolph Hearst Foundation has awarded Augustana College a $100,000 grant for scholarships for students preparing to enter education, public or human service, or journalism professions.
KELO Highlights Augustana FriendsLink Program
KELOLAND TV: Making friends can be tough, especially for people with disabilities. But an organization at Augustana College is bringing people together in a whole new way.
Gronewold Winner of Covenant Award for Christian Faith
"I am truly honored by this recognition, but I would like to emphasize that it is not me, but a loving God working through me to make a difference," Gronewold told Luke Tatge, editor in chief of The Augustana Mirror.
Augie Green Earns Award for Environmental Initiative
Augie Green earned runner-up honors in the Do You Dream in Green competition at the 2008 Plain Green Conference held at the Washington Pavilion in Sioux Falls. Entered in the Plain Action category, Augie Green won $300 for its submission titled "The Green Initiative.
Christiansen, Hofer Recipients of Behrens Scholarship Awards
Augustana nursing majors Whitney Hofer and Rachel Christiansen have been named winners of 2008 Dr. Jeff Behrens Scholarship Awards. The awards honor the memory of Dr. Jeff Behrens, who was a driving force behind the orthopedic excellence of Sanford Orthopedics and Sports Medicine.
Alumnus Receives NIH Post-Graduate Fellowship
Ryan Mello, class of 2006, has been awarded a pre-doctoral fellowship by the National Institutes of Health through the Ruth L. Kirschstein National Research Service Award program.


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Friday, July 19, 2013
The Silent Majority
In triage, you don't spend time with the expectant.
Doctors are keeping their heads down. They are still seeing patients. They are still going to work and taking the calls.
But they are tired. They are frustrated by the system that puts the system of care before the people doing the caring and those needing care. They are tired of the empty promises. Like the promises that staring at a keyboard will fix things, do things better, save money. It's complicated, this health care thing, right? We are told we need more automation. We need more quality managers. We need more safety officers to see more people with less to keep it safe. We need more administrators to implement the rules: more people willing to take less to make it work. Complicated, I tell you.
But the promises, we're learning, have been part empty, for they have enriched the system for the system's sake while leaving the people the system is supposed to help, increasingly broke. We're $500 billion over budget so far and counting.
Promises are for politicians and business people. Real health care workers don't make promises, they do the best they can with what God gave us. As patch after destructive patch of interweaving laws and back-slapping favors are handed out in Washington, corporate board rooms, and union meeting halls, a silent health care majority watches from their peripheral vision, trying not to notice, trying not to be disgusted, for the work for them never ends. The silent majority is waking to the fact that the business part of health care was, is, and somehow forever shall be, broken. There is simply too much money involved, too much economic return that can still be made, too many opportunities to deceive others for personal gain, too many people, too many workers, too much of our economy, to accept that things will ever really change. Too very, very big...
... to fail.
Like Detroit.
I sit before a computer screen that says "Order entry:" I no longer need a pen thanks to handsome government subsidies and a push to centralize and nationalize. Let others do the deciding.
I type in an order.
Five choices instantly appear based an a sophisticated word-search algorithm. I find what my patient and I, as their caregiver, need. I click on the item.
But a price never shown. So there is never a discussion about cost. That's the intent. There is never a word about the difference of retail price and what it really costs or what you'll really have to pay. Like a shopping spree without the prices. Because, according to others, doctors should not think of these things when health care is involved, nor should Congress - it's about your health, remember?
So thousands and thousands of your dollars are put at risk, dear patient, with a single click of a button. Courtesy of government subsidies. And you will never know. Nor will I, as I load the gun of your economic destruction.
So efficient. So clean. So tidy.
How was I supposed to know I ordered a collection agency for you, too?
But the silent majority is stirring. They are upset they must pay their mandate, upset the corporate guys don't. The are seeing the bills, the denials, and the undecipherable bills. They are seeing the cost.
The Silent Majority is stirring.
Because they have a check box, too.
In November, 2014.
4 comments:
- Lisa said...
Thank you. I wouldn't shop at a store that doesn't post the prices. Neither do I eat at restaurants where there is no price given for each entree. That's just stupid. It says I have more money than brains. I knew that cancer treatment was going to cost 60 grand to extend my life for 7-10 months, would I take it? I only got a defibrillator after I'd blown through my out of pocket for the year. I knew it was ungodly expensive and I also knew that chances are that it will never fire a charge. I hope it doesn't. Would I pay the 80 grand that it took to have it installed, probably not. Real reform will come in health care when patients are told what they are spending. I'm sure that what I alone have spent in care that was repetitive and most likely unnecessary, or could have been achieved with a cheaper therapy is approaching a million. But I'm not given the option to either know what I'm spending or even know that there is a cheaper, usually easier way to do this. I have a difficult time getting my doctors to share blood test results. I'm sure that it doesn't change that much over the course of a few days. But they don't like to share. Doc A has to turn over the result, but but Doc B thinks he needs a new test. It's infuriating, maddening. I'd love to jump ship, but then what?
- Fri Jul 19, 03:29:00 PM CDT
Thank You for this writing.
Now I feel I am not alone.
It seems the system has decided the patient
and the doctor (or care worker, as we are now called), are both left out.
No knowledge of the cost of what we are ordering, no knowledge of whether the patient will actually be able to
afford what we are ordering: and therefore no ability to even have a frank discussion about the cost.
Once, when I had my colonoscopy screening, I asked the GI physician if I could forgo the anesthesia as I wanted to watch the video monitor, and I had no one with me to guide me home (a requirement by the hospital).
When I received the EOB I noticed my insurance was billed 298.00 for the anesthesia that I did not have.
Although I tried my best to correct this inaccurate bill, I was told by the hospital billing and accounting department that these two items (the screening colonoscopy and the anesthesia) are LINKED. And in his 12 years of experience, he has never been able to unLINK them-even if the anesthesia was never given.
I was unable to keep that insurance as the premium became too high for me to bear, eventually.
- Fri Jul 19, 03:41:00 PM CDT
Doc, you may rail against Obama, but if not for him we would still be doing it the old way with no concern for the cost. You either had insurance or you didn't. If you didn't you got your health care at the ER. Take note of the two above comments. Their complaints originate with the hospitals and their contracts with insurance companies.
I've been asking about prices for years. Every doctor was clueless, and worse, was contemptuous of the question. Well, god bless Obamacare for beginning to put an end to such ignorance.
- Sat Jul 20, 11:07:00 AM CDT
Great post! Your analysis of the current bureacratic economic morass of unnecessary overhead and and conflicting political agendas is right on. More than providers are waiting to pull the lever in 2014. Thank you for your insight and articulate picture of where we truely are in health care delivery and how doctors have been systematically pushed aside in the all important patient doctor personal encounter.
- Sun Jul 21, 01:39:00 PM CDT


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Sharp to invest two bln dlrs to boost LCD panel output
Japanese electronics maker Sharp Corp. said it will invest two billion dollars to increase output of liquid crystal display (LCD) panels for digital TVs, mobile phones and game consoles.
Sharp said Wednesday that it would spend 150 billion yen (1.5 billion dollars) to launch in October 2006 its new Kameyama No. 2 plant in western Japan, which together with the existing No. 1 plant would make LCD panels for flat-screen televisions.
The company plans to double output capacity at the new plant at its Kameyama complex from an initial 15,000 LCD panels a month to 30,000 in 2007.
Sharp also plans to increase capacity at the existing Kameyama No. 1 plant to 45,000 panels a month by April 2005, from the current 27,000 panels.
"Demand for digital broadcast-ready LCD TV sets will expand rapidly both in and outside Japan," Sharp said in a statement.
For terrestrial digital high-definition television broadcasts, LCD panels are better than plasma display panels, although the latter is a more dominant format, Sharp president Katsuhiko Machida told a news conference.
"As competition with PDP (plasma display panel) makers is becoming tougher, we will work more closely with suppliers in developing new parts while aiming to halve the turnaround time (to seven days) to maintain cost competitiveness," he said.
"Our business climate will become more severe this year, owing to South Korean, Taiwanese and Chinese makers catching up, which will increase downward pressure on product prices," he added.
Sharp aims to boost sales of LCD televisions to 4.5 million in the fiscal year to March 2006, and to 7.0 million for the following year, from an estimated 2.7 million in the year to March 2005.
The company also plans to spend 53 billion yen on adding a third line to the Mie No. 3 Plant, south of its Kameyama complex, with a monthly capacity of 6.8 million system LCDs used in game consoles and mobile phone handsets.
When the No. 3 plant starts operations in April 2005, Sharp will have a combined production capacity of 19 million system LCD panels a month.
Sharp aims to increase LCD business revenue to 830 billion yen in the year to March 2006, from 730 billion yen projected for the year to March 2005.
From Yahoo Asia


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not be lost on (someone)(redirected from are not lost on you)
Like this video? Subscribe to our free daily email and get a new idiom video every day!
not be lost on (someone)
To have a significant or noticeable impact or effect on someone; to be valued, appreciated, or understood by someone. I assure you, Senator, the implications and possible consequences of the proposed law have not been lost on me. I hope all our efforts to help your career have not been lost on you, John.


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More info coming soon...
More info coming soon...
At Battersea Orthodontic Practice our orthodontists, dental nurses and reception staff always aim to provide the highest standard of care and service for our patients.
We passed our recent CQC inspection with flying colours, contact us today to book your appointment.
104 Battersea Rise, London, SW11 1EJ
Tel: 020 7924 4224
Email: firstname.lastname@example.com
Copyright 2018 © Battersea Orthodontic Practice – All rights reserved.


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Regular Price: £173.00
Special Price £86.50
Regular Price: £179.00
Special Price £89.50
Far from ordinary, Kenzo Kids is an ultra-cool clothing brand popping with bright colours and imaginative prints. Kenzo makes charismatic clothing that has everyone talking. The iconic and quirky tiger logo is at the heart of this fashion brand and has unsurprisingly gained cult status. Kenzo's unmistakable presence is a must-have in any fashion-conscious child's wardrobe. Our kooky kids edit showcases the very best of Kenzo, with everything from 'exclusive edition' bikinis to logo printed dresses and artfully brilliant tees and jumpers, shorts, dresses, coats, joggers, cute babywear, and cool accessories and shoes.


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Results 41 to 44 of 44
Thread: Toyota Highlander Hybrid Brakes
I have a 2006 400h i have
I have a 2006 400h i have had nothing but trouble with it. they have changed the breaks twice .the break actuator two times. and i still have a clunk nose.i have had to go to court on the lemon law.i have had it in 6 times to be repaired.they were very nice .but when you pay good money for a car i feel that you should not have to keep taking it back for repairs just so you can drive it.
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Today, I had to stop quickly
Today, I had to stop quickly to avoid hitting a car that was coming out from a side street. My car stopped on a dime, but every light came on and I could not get the car to move. Long story short, I had it towed to the dealer I use for maintenance, and they said it was the brake accuator. This is a very expensive part! FtinessX3 reported a similar problem about a year ago (see above). Has anyone had the same problem recently? Have you filed a claim? What did your Toyota dealership do?
I just had my 2006
I just had my 2006 Highlander Hybrid Limited in for service yesterday, and one of the items I asked them to check out was a squeek that occurred at the end of a quick stop and occasionally when braking during a turn. They said it was the ABS accuator, but it was not a problem and not a safety issue. They said as long as the noise didn't bother me, I did not need to get it fixed. So I decided not to spend $1,800+ for a repair that was "not necessary."
Today, I was thinking about the answer I was given about tyhe ABS accuator, and it seemd odd tghat a part that was so expensive was "not necessary." I decided to google the topic, I found the comments from other people who have had ABS accuator problems - and it certainly sounds like a safety issue! I am going to call the dealer service manager back today!
I am also going to report it on the NTSB website as explained in the post from FitnessX3. Thank you!
Guyz, pls i have a toyota
Guyz, pls i have a toyota highlander hybrid 2008 model, i was driving the car last week and the brake and abs indicator turned on, pleaseeee i am so confused as to what would have caused this and the solution to it. Some1 please help.


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Carl wrote me again about his ancestors and their relatives.
He had this information about someone named Rita.
He also mentioned the Combe and the Ashley families in his e-mail.
I had to look it up in the more than 100 photos Robin has scanned in 2011 where most of the pictures were of the Bleau and the Combe family.
I found little Rita.
Lovely Rita… circa 1924
Rita is there with her cousins and her two brothers… Joe, with his mouth opened, and Henry on the far right.
This will put a smile on Robin' s face I am sure.


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During its rather protracted production history, the most newsworthy thing about "Men in Black 3" was the furor the size of Will Smith's luxury trailer stirred up among angry New Yorkers.
But the show went on, and we now have our first look at the third installment of the sci-fi comedy series. The first "MiB" was a pleasant surprise, effectively milking the chemistry between Smith and Tommy Lee Jones while running through its clever "aliens in disguise" premise.
The second "MiB" must have been "flashy-thinged" out of our memories, because we seriously can't recall a single thing about. Wasn't Rosario Dawson in it? And the artist formerly known as Lara Flynn Boyle? Maybe.
U.S. & World
In other words, "MiB3" has its work cut out for it. Smith seems to be back in his comfort zone as the smack-talking Agent J, and there are some surprises in the form of Emma Thompson (??) and Josh Brolin, who manages to nail a pitch-perfect Tommy Lee Jones impression with one line of dialogue.
We'll see. "MiB3" hits theaters May 25, 2012.


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The Godfather signed Robert Duvall (Brando interest) - as Tom Hagen
Stunning 8" x 10" press photo for "The Godfather", signed by Robert Duvall, as Tom Hagen.
Tom Hagen is a fictional character in Mario Puzo's novel Godfather and Francis Ford Coppola's films The Godfather and The Godfather Part II.
Robert Duvall is an American actor and filmmaker. He has been nominated for seven Academy Awards (winning for his performance in Tender Mercies),
seven Golden Globes (winning four), and has multiple nominations and one win each of the BAFTA, Screen Actors Guild Award, and Emmy Award.
He received the National Medal of Arts in 2005. Duvall has starred in numerous films and television series, including To Kill a Mockingbird (1962),
The Twilight Zone (1963), The Outer Limits (1964), Bullitt (1968), True Grit (1969), MASH (1970), THX 1138 (1971), Joe Kidd (1972), The Godfather (1972),
The Godfather Part II (1974), The Conversation (1974), Network (1976), Apocalypse Now (1979), The Great Santini (1979), Lonesome Dove (1989),
The Handmaid's Tale (1990), Rambling Rose (1991), and Falling Down (1993).
Signed by:
Robert Duvall
Comes with our own Devon Autographs COA, and Lifetime Authenticity Guarantee.
Devon Autographs [ UACC Registered Dealer #RD336 ]


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The Telegraph is reporting that the BBC is developing an on-demand music service called Playlister, which will provide access to "hundreds of thousands" of tracks for free.
While it sounds like a direct rival for the likes of Spotify and Rdio, the newspaper's numbers suggest that the service would provide a fraction of the songs offered by the pay-for services—but it would be free. It's not really clear what tracks would be offered up: original versions, BBC archive material, something else entirely? It's anybody's guess.
The BBC has spoken about offering up its archive of music recordings for wider consumption in the past, but usually struggled to obtain the rights with which to do so. Apparently the organization has been talking to Spotify about how to side-step the problem, though—so perhaps it now has things sorted.
The newspaper speculates that the service could launch later this year or in early 2013, and it's not clear whether it would be a UK-only or international service. The BBC is apparently holding a digital media press conference this week, though—so we might find out more soon. [Telegraph via Musically via Verge]


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LEWIS HAMILTON has delivered a respectful tribute to former team-mate Jenson Button as Formula One's veteran campaigner stands on the brink of his 250th grands prix this weekend.
Now in his 15th season in F1, only four drivers have started more races than 34-year-old Button - Rubens Barrichello with 322, followed by seven-times champion Michael Schumacher (307), Riccardo Patrese (256) and Jarno Trulli (252).
Hamilton can only admire Button's fortitude and perseverance to carry on in a tough and demanding sport, even more after the loss at the start of the year of his father John who had previously missed just one of his son's races.
Hamilton, partnered by Button for three years at McLaren from 2010-2012, said: "I have a huge amount of respect for Jenson, watching him come back every year, to have that motivation, because as you get older it gets harder.
"It gets harder to train, even for younger people, and every year it gets harder and harder to challenge, and how you spend your energy is different every year.
"Yet every year he is on it, focused, and especially this year as his dad's not with him, who has been with him all these years.
"Even so, he is still there, still working away, and I take my hat off to him. He's a great athlete.
"I can only hope and dream I get to have as long and as successful a career as he has had."
Ahead of reaching the milestone at this weekend's Bahrain Grand Prix, the 2009 world champion concedes it is "crazy" to consider the fact he has been around for so long.
This year, in particular, is another learning experience for Button without his dad by his side, although there is one comment from from John that sticks with him to this day and reminds him why he remains in love with the sport.
Reminiscing, Button said: "The nicest thing anyone ever said to me came from my dad.
"He said: 'You might not be the quickest driver in the world, but you're the best'. Those words meant a lot, and they still do.
"Overall, I'm very happy with my career, even though there have been highs and lows.
"One of the things I'm most proud of is the way I've stacked up against my team-mates.
"I've had 10 of them in 15 seasons, so I've needed to prove myself to the new guy sat beside me virtually every year.
"It's a very funny sport in that respect because even after everything you've achieved, you've still got to prove yourself time and again."
Back in 2011 Button added another fairytale chapter to his career when he won his 200th grands prix start, taking the chequered flag in Hungary with McLaren.
Yet given McLaren are off the pace of Hamilton's frontrunning Mercedes team, iIt would be a major surprise if Button were to mark his latest milestone with a win in Bahrain, which this year stages a night race as part of their 10th anniversary celebrations.


text: Runners, Your Shoes Make a DifferenceThey may not make you run faster or jump higher. Yet the material in the running shoe you wear does seem to make a difference. This study tested different shoes to shed some light on the mechanics of running. When you run, your foot hits the ground with high impact. This study helps prove that the muscles of the leg adjust to this impact through a process called muscle tuning. Muscle tuning lessens the effects of impact on the tissues of the leg. The midsole of running shoes also helps lessen the effects of impact. These researchers tested two different midsoles on six different runners. They found major differences in the muscle tuning between different shoes. And muscle tuning was significantly different between individual runners. Some runners did better with a hard midsole, while others benefitted from a softer one. A better understanding of how our legs work when we run may help researchers find ways to treat or prevent conditions caused by the wear and tear of impact on the body. And who knows, maybe it will spur shoe companies to develop a "super shoe" that really makes us run faster.ReferencesJames M. Wakeling, et al. Altering Muscle Activity in the Lower Extremities by Running with Different Shoes. In Medicine & Science in Sports & Exercise. September 2002. Vol. 34. No. 9. Pp. 1529-1532.


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May 30
What Shall We Say?
By Marsh Chapel
May we pray? Holy God; Holy and mighty; Holy and eternal. May the words of my mouth and the meditations of all our hearts be acceptable in your sight, O God, our rock and our redeemer.
Oh dear. What exactly are we supposed to do here? Or more precisely, what shall we say? After all, to declare with the ancient creeds of the Christian church that divine life is one God in three persons is precisely that, a declaration, a form of speech.
To speak of God is always difficult, if not outright terrifying. What if we get it wrong? If we say something out of line, will God smite us where we stand? More importantly, what if someone believes us? If we are wrong, might we have sent them down a dangerous path? That there is so much at stake in our speech about God is hardly made easier by the fact that the object of speech, God, often seems so inaccessible. It is not like describing a stone that we pick up at the beach, washed ashore by the crashing waves. We can describe the stone to a friend and the friend can look and see whether or not our description meets up with their experience of the stone. But God does not fit in our hands. Saint Anslem said that God is "that than which nothing greater can be thought." One of the implications is that God is so great that the power of human speech to be meaningful in describing God is compromised.
So, why bother to say anything at all? Why not just remain silent in the face of God, who we can barely comprehend? Is it not sheer hubris to attempt to speak of God at all? As a matter of fact, yes, it is sheer hubris to speak of God. Not that pride has ever been a particular deterrent to people going ahead and doing whatever it is they are determined to be about anyway. But there is more to it than pride. It seems that there is a human compulsion to speak. The very first lines of the Tao Te Ching say that "A way that can be walked is not The Way; a name that can be named is not The Name," but it then immediately goes on to say that "Tao is both Named and Nameless. As Nameless, it is the origin of all things; as Named, it is the mother of all things." Similarly, with regard to the Trinity, Augustine notes: "Yet, when the question is asked, What three? human language labors altogether under great poverty of speech. The answer, however, is given, three "persons," not that it might be [completely] spoken, but that it might not be left [wholly] unspoken." To fail to speak, it seems, is as great a sin as the pride of speaking.
This should not be entirely surprising to us. We gathered here in the nave of Marsh Chapel and listening over radio waves and internet signals are a community, and communities are formed out of shared experiences that are then shared again and again in common patterns of speech, in the telling and retelling of stories. Without speech, we would not be. This is the truth of the beginning of the Gospel according to John: "In the beginning was the word."
All right, so we can't speak well, and yet we must speak. But what exactly are we doing when we speak? To speak is not simply to state a fact. Yes, there are what philosophers of language and linguists call locutionary aspects of speech. When we speak we make sounds that are strung together in patterns that comprise words, which are in turn strung together in sentences with grammar and syntax and thus have meaning. However, this is not all that is happening when humans speak. In addition to locutionary aspects, human speech also has illocutionary aspects, in which meaningful words and sentences are spoken in a context so as to bring about some outcome. Human beings speak with intent. Sometimes that intent is merely to describe. "It's really hot outside." More often, however, the intent is to more than merely descriptive. After service, if you find yourself standing on the plaza chatting with a fellow congregant, and that person says "it's really hot outside," it is more than likely that they are suggesting that the two of you should continue your conversation in some nearby shade. You can tell this because if your response is simply to agree, "yes, it is really hot outside," your conversation partner will likely roll their eyes and make the request more explicit, "why don't we go sit in the shade and chat?" Under the illocutionary aspect, we do not merely make intelligible sounds, we ask, request, promise, greet, warn, advise, challenge, encourage, deny and otherwise initiate actions. In speaking, we expect a response.
What kind of action are we undertaking when saying that God is Trinity? And to whom are we speaking? There are two primary contexts in which we speak of God. The first is in the context of worship. It is traditional in the history of Christian worship that following the sermon and leading into the celebration of Holy Communion the congregation would recite together a creed, often the Nicene-Constantinopolitan Creed. The creed usually begins, "I believe." This identifies the creed as what philosopher John Searle identifies as a declarative speech act, one that commits the speaker to the truth of what is said. Entering into a common action of committing to a common truth is a powerful way of drawing people together under what all affirm as the same experience of the same God. This is one way of overcoming the difficulty of the inaccessibility of God to easy perception and thus description.
The other context in which God is spoken of as Trinity is in the context of theological explication. In this context the theologian is enacting what Searle calls a directive speech act that seeks to cause the hearer or reader to do something, usually in this case to believe in God as Trinity as the theologian has laid out the case. Trinitarian theologians seek to make the case that believing in God as Trinity allows for a coherent, consistent, adequate and applicable understanding of God, the world, and our place in the world. Because the account provides coherence, consistency, adequacy and applicability, categories I am borrowing from Alfred North Whitehead, then the hearer or reader is justified in assenting to the theologian's claims.
These then are the two contexts in which we speak of God: worship and theological explication. In the first our speech is declarative, and is addressed to God and to each other, binding us together in a common community. In the second the speech of the theologian is directive, and is addressed to us, calling us to believe in God as Trinity because such belief is justified. At least, these are the ways that talk of God is classically understood. I would like to suggest that limiting ourselves to these two understandings of God-talk is missing an important active dimension in what we are doing when we speak of God.
Speaking of God is not merely declarative, committing ourselves to the truth of what we say, nor merely directive, asking others to believe as we do. To speak of God is to enact a type of speech act that Searle distin
guished as declaration. A declaration does not merely commit the speaker to the truth of what is said, but changes reality to accord with what is said. In a criminal case, when the judge hands down the sentence, the reality of the defendant is no longer 'defendant' but either the one who committed the crime, 'guilty,' or the one who did not commit the crime, 'innocent.' At a wedding, such as the one at which I will officiate this afternoon, the words "I now pronounce you…" are what make the marriage legal, and so are a significant part of what makes the marriage real.
While I identified the declarative and directive classes of speech acts as the classical interpretations of the nature of God-talk, they are so only in terms of a modern western conception. The idea of speaking of God as a declaration that changes reality is actually quite old when we turn to south Asian religious traditions, and also to some very early Christian sacramental theology, some of which survives to this day. In both cases, the understanding that speech has the power to make reality as it is arises in the context of ritual. In south Asia, it was believed that enacting rituals, and particularly speaking the right words in the rituals, maintained the very existence of the world. This belief was crucial to the religious heritage of the region and speech remains central to Hindu theologies. For Christians, the idea of anamnesis is that in reciting salvation history in the Eucharistic prayers, time collapses together to make the ritual expression of the suffering, death and resurrection of Jesus one with its first occurrence in first century Palestine and with every other anamnetic retelling past, present and future. Thus, the Eucharistic prayer is not simply a retelling of what happened, but the actual happening of salvation history, the enactment of the reality of salvation history. The declaration of the story makes it so.
Of course, it is one thing to say that declaration makes socially constructed realities so, but it would seem to be nonsensical to believe that simply saying that "the sky is chartreuse" could make it so. Indeed, there is a significant difference between social reality and brute reality. And we run into trouble if we say that the declaration of God as Trinity makes God Trinity because most of us would like to believe that God is a part of brute reality, something given to be experienced, not a projection arising out of common affirmation. But this is indeed what South Asian and early Christian theologies claimed, that the very being of the brute world is dependent upon ritual. Today we may wish to dissent from this strong claim about the capacity of declaration. But perhaps we need not protest too much.
Recent work on ritual by Boston University professors Adam Seligman and Robert Weller make the case that ritual, broadly understood, creates subjunctive, as-if spaces that allow us to cope with the broken, disjunct, fractured experience of life. Ritual gives us the ability to draw together the strewn about pieces of our lives and our experience of the world into something resembling a unified whole. The fact of the matter is that our experience is not normally coherent, consistent, adequate or applicable across the many arenas of life in the world, and we ourselves are not coherent, consistent, adequate or applicable. This is why in religious life we acknowledge the deep chasms and fissures of the human condition. As Stephen Prothero, another BU professor, so carefully points out in his most recent book, God Is Not One, different religious traditions make different claims about the contours of those chasms and fissures, and therefore prescribe different ways of unifying them. Nevertheless, it is fundamental to religious life that there is something wrong with the world, that we ourselves are not well suited to overcoming those wrongs, and that it is only by acknowledging and giving ourselves over to the ultimacy of ultimate reality that we can get by. As Paul says, "We also boast in our sufferings, knowing that suffering produces endurance, and endurance produces character, and character produces hope, and hope does not disappoint us, because God's love has been poured into our hearts."
To speak of God is to create a ritual, subjunctive, as-if space in which all of the chasms and fissures of our broken lives and experience fit together coherently, consistently, adequately and applicably. But our speech about God must in some way acknowledge the subjunctive character of the space. The Christian doctrine of the Trinity does this, as do other conceptions of ultimate reality. The doctrine of the Trinity insists that God is one, thus creating the subjunctive space of wholeness. But the doctrine of the Trinity can only understand God to be one in terms of three persons, three expressions, thereby acknowledging that the reality of God can only be coherent, consistent, adequate and applicable to us in our brokenness and our disjunct lives in a fractured world insofar as God is not one. This is to say that God participates in our desire for unity and God participates in the reality of fractured existence. How God can do this, how God can be both transcendent and immanent, is not something that we can speak as a fact but is something that God speaks as a declaration. The unity of God, how it is that these three are one, is not something that we can bear; it is a mystery. "When the Spirit of truth comes, he will guide you into all the truth; for he will not speak on his own, but will speak whatever he hears, and he will declare to you the things that are to come. He will glorify me, because he will take what is mine and declare it to you." The declaration of God is that ultimate unity – ultimate coherence, consistency, adequacy and applicability – is not for us now, except in the glimpses of grace we experience when we make our own declaration of God the Trinity. Amen.
University Chaplain for Community Life