text:
The University's Research Services Team can support you with:
Open Access
Record Data Management
Impact Measurement
This is a list of resources for finding theses and dissertations.
SAGE Research Methods is a research methods tool created to help researchers, faculty and students with their research projects. Researchers can explore methods concepts to help them design research projects, understand particular methods or identify a new method, conduct their research, and write up their findings. Since SAGE Research Methods focuses on methodology rather than disciplines, it can be used across the social sciences, health sciences, and more.
Online help is available from within SAGE Research Methods; there is also a dedicated LibGuide produced by SAGE itself:
If you want to keep abreast of current developments in your field, many subject databases provide email updates. The following are also good ways to stay up to date.

subset: commoncrawl


text:
Introducing the marijuana vending machine.
A Russian jet buzzed a US Warship in the Black Sea, threateningly.
Don't miss tonight's "blood moon" lunar eclipse.
Utah authorities found seven dead babies in a woman's home.
"Seaweed." Finally we can talk to dolphins.
Graphene will change our lives.
There's a pyramid in North Dakota.
An abused Albuquerque toddler is hospitalized.
Ho Ho's had a sewage problem, but they're open again now.
Happy birthday, Rod Steiger.


text:
Mt. Airy author's new memoir explores issues of LGBT children caring for aging parents
by Len Lear
Long-time Mt. Airy resident Janet Mason, 53, has just written a memoir, "Tea Leaves," which her publisher, Bella Books, maintains is the first LGBT (Lesbian/Gay/Bi-sexual/Transgendered) nonfiction book in over a decade to address directly the issues of caring for elderly parents.
"Out and Aging," a 2006 report, found that 36 percent of LGBT Boomers are caring for aging parents. One significant reason why a higher percentage of gays care for aging parents than heterosexuals is that gays are less likely to have children of their own to care for, freeing them up to spend more time and resources on their own elderly parents.
"Tea Leaves" begins when the author's mother, Jane, is diagnosed with fourth-stage cancer in 1993. A dutiful daughter, Mason proceeds to take care of her mother, 74, and enters a deeper understanding of her own life through her mother's stories. Her grandmother (born in 1899) was a white glove-wearing lady of her generation, and Janet's mother (born in 1920) was an office worker and feminist ahead of her time. The narrator has taken the foundation of her mother's life and forged her own. "Tea Leaves" is a story of gender and class, identity and sexuality but, most of all, it is about love.
"Tea Leaves" also includes a backdrop of Philadelphia history including the textile mills in Kensington, where Mason's grandmother worked as a spinner, and the Lighthouse in North Philadelphia, which in the 1920s was a charitable day program for the children of single mothers, most of whom worked in the textile mills.
"So many people," said Janet last week, "regardless if they are gay or not, become the caretakers of their aging parents. In my own experience, I was an only child, so there were not any siblings to look to. But taking care of my mother was never a burden. It was simply the right thing to do – and I could never have imagined not doing it."
Mason, who teaches creative writing at the Mt. Airy Learning Tree, will also be reading this summer at Big Blue Marble Bookstore on Carpenter Lane in Mt. Airy and at Mt. Airy Arts Garage.
"I have always been a writer," said Mason. "It is almost as natural to me as breathing. As a child, I was always making up stories, and often I wrote them down. I think writers experience the world differently than other people; we escape into imagination and then come back and explore what intrigues and haunts us. We make sense of things by writing about them. This was very true in the writing of 'Tea Leaves.' I wrote about my mother's final months and my experience in caring for her."
In her 20s and 30s, Janet primarily wrote poetry. She was "discovered" by Insight To Riot Press, a publishing collective in Philadelphia, which published several slim volumes of her poetry. "I found that my poems were getting longer, and then I started writing short stories and just finished a novel that is set in the 1920s which is about my mother's father, who abandoned his wife and two daughters (my mother and my aunt) when my mother was seven. I witnessed her pain at being abandoned by her father and always wondered about him – my grandfather. When I finished the last sentence, I realized that the writing of the novel had been, for me, an act of forgiveness."
Mason grew up in Levittown, Pa., and graduated from Neshaminy Maple Point High School and Temple University as a journalism major. She has held many positions in communications and teaching. She worked for Jewish Educational and Vocational Services for five and a half years until last June and prior to that with the National Adoption Center for several years. She also taught creative writing at Temple University Center City for eight years until the fall of 2010, when the Continuing Education Program was discontinued. "Teaching has always been a sideline for me, but it is also the most rewarding work that I have done."
Subconsciously, revealed the Mt. Airy author, she always knew that she was gay. As a child, she always felt different and was in many ways taking refuge in reading, music and her own inner world. "I 'came out' shortly after college – when I was 23," she said. "I was living on my own in a studio apartment in Germantown and creating my life – as a lesbian and as a writer. It seems like the world has changed immensely since my early 20s. At the same time, I am always cautious about whom I open up to – especially in the workplace where you have something to lose.
"Yes, I have experienced discrimination in housing and in the workplace and also random violence on the street many years ago. The threat of violence was always there. In recent years, when I worked in Center City, I would see young women together holding hands on the street, and the sight of them always made me happy. It is true that we are living in a time of backlash and that many young gay people are having a very difficult time and still need our help.
"But it is also true that the world is a freer place than it used to be. I am working with PFLAG (Parents and Friends of Lesbians and Gays) chapters across the country, promoting 'Tea Leaves.' PFLAG has been around since the 1970s. I was thinking back on the meetings I attended in Philadelphia when I first came out and how helpful the organization was to both my mother and father. It is common for parents to not want their children to be gay because they don't want them to experience discrimination. But more harm can result by denying your true self. And I think that is something that transcends being gay."
"Tea Leaves" has been getting rave reviews from critics. For example, prominent author and historian Karen S. Mittelman recent wrote that "Tea Leaves" is a "heartbreaking story of loss and at the same time a fierce and jubilant tribute. It reminds us of the way as daughters our accomplishments are always entangled in our mothers' disappointed dreams. As Janet Mason reveals the legacy of frustration, shame and rage that passed like an unspoken heirloom through generations of her working-class family, she also uncovers a stubborn, bright hope and a keen sense of injustice that are equally her inheritance."
Mason has been with her partner, Barbara, for 29 years in Mt. Airy. (Barbara is also a character in "Tea Leaves.") "I love Mt. Airy," said Janet. "As a child I always wanted to live in a diverse community, surrounded by people who read books. Mt. Airy has long been known as a safe haven for lesbians, but the beauty of being gay and living here is that it does not matter. People socialize according to their interests – music or art, for instance. I was working in Center City full-time during the day and teaching at night and spending a lot of time on the commuter train for the past decade, and in the past year I have come to appreciate Mt. Airy more than ever. It is a beautiful place – the trees, the houses and yes, the people too – and a true community."
"Tea Leaves" is available through bookstores (they can order it if they don't have it in stock) or online through Amazon and the publisher's site (Bella Books, http://www.bellabooks.com/9781594932786-prod.html) and other online bookstores as well. You can contact Janet Mason at firstname.lastname@example.com


text:
Rihanna unleashed her inner Geisha for Coldplay's "Princess Of China" video– a hit that she and the group performed at the 2012 Grammy awards.
Though the band doesn't make an appearance in the colorful visuals, Rihanna's revealing attire and Chinese getup is appealing enough!
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text:
I said I wasn't going to just link to articles. But this one from MIT's Technology Journal contains the links I'd otherwise want to research for myself. So have a look.
In brief: there's been a lot of research over the last thirty years in speech to text rendition, and products on the market. But MIT appears to have cracked two additional problems. First, many lecturers aren't native English speakers – a top university is a polyglot, international community. So software that's designed for standard English (or American) won't do. Second, of course, in lectures there are many specialist terms not in a standard lexicon (whatever the subject).
So for MIT to offer its students a Lecture Search online tool, based on videos of lectures, is pretty remarkable. Read the story here: Searching Video Lectures (MIT Technology Journal, 26 Nov 2007).


text:
Here Comes The Bus
Chelsea Shar
Monday, November 20, 2017
Download the Here Comes The Bus app on your smart phone to learn where your child's bus is- in real time! Receive push notifications and email alerts and send your child to the bus stop at just the right time every time.
Download the app and click the "sign up" button. Enter the school code 74007, and complete your user profile.
Get alerts when the bus is near your home or bus stop and when the bus lets your child off. No more waiting out in the cold or rain for the bus and get alerts if your child's bus is running late at the end of the day.


text:
Orbital Welding Technology for Pharmaceutical Piping Systems
Orbital welding technology for pharmaceutical piping systems
Figure 1. Orbital welding operators installing a stainless steel piping system in a pharmaceutical plant in the UK. (Photo courtesy of A.T.W. Services)
The capability of making a
smooth, crevice-free inner weld bead on a repeatable basis, has led, over the
past decade, to orbital welding becoming the preferred joining technology for
biopharmaceutical process piping.
The expanding biopharmaceutical industry in the USA has placed an increasing emphasis on quality standards and documentation in order to expedite the approval process for new therapeutic products by the FDA (United States Food and Drug Administration).
The approval process requires that the facility in which a new drug is produced must be designed, constructed and commissioned so that it meets the criteria for process validation. Failure to achieve validation on the first attempt can be very costly to the facility owner, so maintaining quality from the design phase throughout the construction process is essential. The quality inherent in orbital welding joining technology is consistent with the goals of the CGMP (Current Good Manufacturing Practices) for achieving hygienic pharmaceutical piping systems that will have no adverse affect on the products that pass through them.
critical process systems
In validating the critical process systems in a new or modified facility, the FDA will seek to determine whether the requirements of three key documents, the CGMP, the ASME (American Society of Mechanical Engineers) B.31.3 Process Piping Code, and the project specifications have been met.1
Of these documents, the most significant is 21 CFR (Code of Federal Regulations) B211 which specifies how the various components in pharmaceutical manufacturing facilities are to be constructed. 21 CFR B211.65 Subpart D states:
(a) Equipment shall be constructed so that surfaces that contact components, in-process materials, or drug products shall not be reactive, additive or absorptive so as to alter the safety, identity, strength, quality, or purity of the drug product beyond the official or other established requirements.
The FDA is very non-specific about
how a critical piping system should be constructed, but relies upon the
requirements detailed in the ASME B31.3 Process Piping Code and the ASME
Bioprocessing Equipment Standard (BPE-97). It should be noted that a code is
required by law, while a standard provides generally accepted industry
The ASME B31.3 Process Piping Code gives to the owner the ultimate responsibility for documenting to the FDA that the critical piping systems have been manufactured, fabricated, and installed according to the CGMPs.
Welding is an important aspect of piping system design and fabrication. ASME B31.3 provides acceptance criteria for welds (Table 341.3.2), details the types of examinations required, the number of welds to be inspected, and establishes qualifications for welding inspectors. In 1989, representatives of the emerging bioprocess industry came together with the realisation that existing standards did not adequately meet the need for design and construction of equipment to be used in critical bioprocess piping systems. A consensus was reached on the need for equipment design that would be both cleanable and sterilizable. Special emphasis was placed on the quality of weld surfaces once the required strength was present. The ASME published the ASME Bioprocessing Equipment Standard (BPE-97) in 1997.
Figure 2. Stainless steel piping system installed with orbital welding at a UK pharmaceutical installation. Tank bottoms and piping are sloped for drainability. (Photo courtesy of A.T.W. Services, Inc).
Figure 3. Recent recommendations call for reduced deadleg L/Ds to improve cleanability and sterilisability. Orbital welding is ideal for this application, as shown on this orbital weld of a short sanitary ferrule to a pulled tee.
BPE-97. Qualification to ASME BPE-97 requires that welds be certified to ASME
Section IX of the Boiler and Pressure Vessel Code and ANSI/ASME B31.3 Process
Piping. This requires that a Q.A. manual and a Q.A. program be in effect with a
set of weld standards which reference the BPE Standard. ASME Section IX is done
to verify the structural integrity of the weldments. To meet this requirement
sample welds are subjected to bend tests to verify weld ductility, and tensile
testing is done to assure that welds meet the minimum tensile strength
specified for the base material. The results of these tests are documented as
part of the WPS (Weld Procedure Specification) Form QW-482*, and the PQR
(Procedure Qualification Record) Form QW-483*. Welders and welding operators
may be qualified by making acceptable test welds and documenting test results
on Form QW-484*. Welder tests require six linear inches of weld or multiple
coupons, but not more than four.
It should be noted that hot WFI water, circulated at temperatures above 40ºC, may be classified as category M fluid service in ASME B31.3, which includes substances which will do irreparable harm in case of a piping system failure in which the contained process fluid comes into contact with human tissue. Weld and inspection criteria for this category are more stringent than for normal fluid service. 21CFR B211.65, Equipment Construction and B211.67, Equipment Cleaning, state that the materials used must be suitable for their intended use which would include the ability to withstand high temperatures and pressures as well as the ability to hold up to sterilising and sanitising agents. Clearly, orbitally welded stainless steel meets these criteria.
While ASME B31.3 was written with manual welding in mind, ASME BPE-97 recommends the use of orbital or machine welding for bioprocess piping. Manual welding may be used, with the owner's permission, only when using an orbital weld head would create a deadleg. A deadleg is defined as a pocket, tee, or extension from a primary piping run that exceeds a defined number of pipe diameters from the I.D. of the primary pipe.
In ASME BPE-97 (Table SD-1) a deadleg (L/D) of 2:1 is considered to be an achievable target value for bioprocessing systems where L is the length of the extension measured from the OD of the primary pipe, and D is the I.D. of the extension. Deadlegs are undesirable because they are difficult to clean and maintain in a sterile condition and may represent an unacceptable bioburden to the system. Where they exist, they should be designed so that it is possible to flush through them.
Intelligent use of orbital welding
Figure 4. Left: manual weld taken from an operating pharmaceutical plant. Note lack of penetration, misalignment, discoloration, crevices and protruding material on the product contact surface. Right: orbital weld on 316L stainless steel tubing. Note uniform, even, fully penetrated weld bead and essentially flat weld profile with no concavity or convexity. Parts are well-aligned and the weld has minimal discoloration of the HAZ, meeting most biopharmaceutical specifications.
The intelligent use of orbital welding technology can help to keep deadlegs to
the required minimum. Some orbital weld heads have provisions for locating the
tungsten electrode close to the edge of the head to accommodate parts with
short "stick-outs" such as welding short sanitary ferrules to stubs
on transfer panels or to pulled tees, as shown in Figure 3. Narrow weld heads
are now in use with reduced axial clearances that make it possible to orbitally
weld fittings-to-fittings that could not be welded with standard weld heads.
For areas with limited radial clearances it is important to use a weld head that is as small as possible for the tubing being welded. Contractors tent to use a single weld head to accommodate all sizes from 1 inch to 4 inches, which is practical for most situations. However, some of the joints on smaller tube sizes that have inadequate radial clearance for a large weld head might be accessible with a smaller weld head. In designing piping systems, allowances should be made to allow for placement of orbital weld heads and eliminate insofar as possible the need for manual welds.
International Society of Pharmaceutical Engineers is publishing a series of
ISPE Baseline Guides developed by ISPE in cooperation with the FDA to establish
a baseline approach to new and renovated facility design, construction
commissioning and qualification. The intent is to document current industry
practice for facilities and systems used for production of pharmaceutical
products and medical devices and to avoid unnecessary spending on facility
features that have no impact on product quality. Volume 4: Water and Steam
Guide recommends the use of orbital welding for the installation of
pharmaceutical water systems, citing the smooth inner weld bead.4
The ASME BPE-97 Standard recognizes the importance of the surface quality of welds for maintaining the cleanability and sterilizability of piping systems. A smooth internal surface finish of the piping system, including the welds, is important for controlling the buildup of biofilm that could contaminate the product.
The Materials Joining part of ASME BPE-97 requires that the weld criteria of ASME B31.3 which prohibits weld discontinuities such as cracks, voids, porosity, undercut, lack-of-fusion, and incomplete penetration that would affect the structural integrity of welds be met but, in addition, provides visual weld criteria that are important for maintaining the hygienic condition of the piping system.
Welds must be fully penetrated with good alignment, with a flat OD and ID profile. An unpenetrated weld has a crevice which may not be reached by CIP cleaning and becomes a refuge for bacteria. Excessive I.D. concavity, convexity, or misalignment, that could interfere with proper draining of the system and allow pooling of fluid where bacteria could gain a foothold presents an unacceptable bioburden to the system.
Discoloration of the weld
Any discoloration of the weld or HAZ as a result of oxidation during welding must be held to a minimum. A light discoloration may be permissible if it is tight to the surface, but the amount allowed (if any) for a particular installation is subject to agreement between the owner/user and the contractor. Discoloration has been shown to be proportional to the amount of oxygen (and moisture) in the ID purge gas which is usually argon. A cryogenic source (dewar or bulk gas supply) is recommended for urging during welding of high purity pharmaceutical water systems.
Oxygen concentrations in the low parts per million range in argon will usually produce welds with light or no discoloration assuming the purge time is sufficient and there are no leaks in the purge system. Purifiers are available that bring the oxygen (and moisture) levels to the low parts per billion (ppb) range which will usually, but not always, produce welds with no visible discoloration. Purge procedures, including flow rates used on specific weld heads and for ID purges, specified levels of argon purity, and discoloration criteria for welds are detailed in the project specification that is prepared by the architect engineering firm and the contractor in advance of construction.
In validating a piping system, the most important determinants of water quality monitored by the FDA are the (live) bacterial count and endotoxins which are produced from (dead) bacterial cell walls.8 Full-penetration crevice-free welds with a smooth I.D. surface are important for meeting these qualifications.
and documentation
Figure 5. AMI Model 8-4000 weld head welding a stainless steel elbow to a tube. This narrow weld head provides reduced axial clearances, increasing the number of joints that can be accommodated with orbital welding equipment. This head is water-cooled to permit a high duty cycle.
An inspection plan detailing the types of examinations to be made shall be
agreed to in advance of the job by the owner/user and contractor. ASME BPE-97
requires that all welds be inspected visually on the OD, and that a minimum of
20% be selected at random for internal inspection with a borescope. The reject
rates for orbital welding in biopharmaceutical applications have been extremely
By refining their standard operating procedures which are detailed in the project specifications, mechanical contractors have documented reject rates for orbital welding as low as 0.2%. The ASME BPE-97 Part SD Design for Sterility and Cleanability lists the kinds of documentation that may be used to verify conformance with sterility and cleanability. The kinds of documentation shall be agreed to at the outset of a design project by the owner/user and the manufacturer (installing contractor).
These would typically include (but not be limited to) material handling procedures, welding procedures, mechanical and electrical polishing procedures, installation procedures, surface finish certifications, shop passivation procedures, mill test reports (MTRs) on tubing, etc.
Figure 6. Weld schedule print-outs can be used as part of the weld procedure documentation package.
It would also include detailed instructions for receiving, inspection of
incoming materials, fabrication, cutting, end-preparation, cleaning of weld
components and provision for a clean area set aside for welding. Tracking of
tubing material heats and control of diameters and wall thicknesses for
specific applications should also be defined.
This information would be detailed in the project specification listed in ASME BPE-97 Part SD Design for Sterility and Cleanability shall also be retained by the owner/user for a period of at least three years.
resistance of orbital welds
Validation of a piping system for high purity water proceeds in three phases: 1) at system start-up, 2) when the system is up and running, and 3) after a period of operation of about a year. Water samples must be collected and analysed at specified intervals to demonstrate that the system produces water of acceptable quality on a continuous basis.
Weld quality is most important for the long-term successful operation of the system. Rouging, a form of corrosion sometimes associated with welds in pharmaceutical piping systems, is fairly common and may affect water quality. When properly welded with an adequate purge of the joint I.D. and passivated after welding, orbital welds on 316L stainless steel have pitting potentials equivalent to those of unwelded tubing which is indicative of good corrosion resistance.5
Use of orbital welding in biopharmaceutical industry
Orbital welding, which uses the GTAW process, is used in the biopharmaceutical industry for piping systems which have direct or indirect contact with the product and may also be used for other, less critical, systems. These include WFI (water for injection), clean steam, and product lines. It is also used for connecting tanks and vessels to the piping systems, in construction of equipment such as multi-effect stills, and to connect bioprocess equipment mounted on skids.
Typical tubing diameters for biopharmaceutical applications are 1 to 4 inches OD, but 1/2 inch OD tubing for instrumentation tubing supplying bioreactors was welded orbitally by B. Braun Biotech. Autogenous welds up to 7 inches in diameter can be done in enclosed orbital weld heads, but larger tube and pipe sizes require the use of orbital welding equipment with filler wire capabilities.
Power supplies are microprocessor-controlled. The weld parameters controlled by the power supply include primary and background welding currents, pulse times, rotor travel speed (RPM), level times, rotation delay, and purge times. These are recorded on a weld schedule for each size and wall thickness of tube or pipe and stored in the power supply memory. They are easily recalled for welding and the schedules can be modified for different heats of materials or for tube-to-fitting welds and the changes stored in memory as needed.
Print-outs from the power supply may include the weld identification number, the operator's name, and the serial numbers of the power supply and the weld head. This information can be used in conjunction with the welding log as part of the documentation package.
Latin America
Figure 7. Orbital welders at Fiocruz Instituto de Tecnologia em Imunobiologicos vaccine plant near Rio de Janeiro in Brazil.
The use of orbital welding is expanding in Latin America. Fiocruz Instituto de
Tecnologia em Imunobiologicos used orbital welding in the fabrication of a new
building used for the manufacture of vaccines. Orbital welding was used for
joining the WFI piping, the DI loop piping, as well as service piping for cold
water, air, and steam systems. Type 316L stainless steel tubing was used for
both WFI and DI water systems. Cold water is used for washing glassware used in
the plant, hot DI water is used for rinsing the glassware, and air for drying
Engineering contractor, Termo Engenharia Ltda, wanted to upgrade its welding procedures and standards to a level that would satisfy the FDA in the USA since Fiocruz intended to export its products. The installation was very successful and Fiocruz is planning to use orbital welding on another new facility at the same location.
Other Latin American pharmaceutical users of orbital welding include Schering do Brasil, and orbital welding is being used in plants for the manufacture of cosmetics and other hygienic applications such as breweries, dairies and juice packagers throughout Latin America.
Productivity is typically higher for orbitally welded systems than for comparable manual installations. Productivity gains are achieved through reduced time to weld each joint as well as lower reject rates and reduced need for rework. Thus orbital welding is eminently suitable for "fast-track" construction projects without sacrificing quality.
During validation, the FDA will examine all the documentation to make certain that procedures outlined in the project specification have been followed and properly documented in accordance with the CGMP. Orbital welding done in compliance with the ASME Bioprocessing Equipment Standard, which by reference includes ASME B31.3 Process Piping and ASME Section IX of the Boiler and Pressure Vessel Code, is a key component in achieving pharmaceutical piping system validation in a timely manner.
The repeatability of the process makes it possible to achieve crevice-free welds with a smooth surface that can be maintained in a clean and sterile condition on a routine basis. The smoother surface decreases the affinity for colonization and growth of microorganisms and increases the efficacy of CIP.
Similarly, the controlled heat input of orbital welding combined with the use of proper purging technology and passivation results in welds that are comparable in corrosion resistance to unwelded base materials. Thus orbitally welded systems, installed with proper fabrication techniques and documentation, are in compliance with 21 CFR B211 Subpart D facilitating piping system validation as well as providing excellent performance in service.
By Barbara K. Henon, Ph.D., and Eng. Angel Brond, Arc Machines, Inc.
1. Lohnes, J. Codes and standards: Critical process piping systems requirements as keys to success. InSPEct. ISPE San Diego Chapter Newsletter, Issue #4, 1999.
2. ASME B31.3 Process Piping Code (1996 Edition) ASME, 22 Law Drive, Box 2900, Fairfield, New Jersey 07007-2900, USA.
3. ASME Section IX of the Boiler and Pressure Vessel Code.
4. ISPE Baseline Pharmaceutical Engineering Guides Vol. 4. Water and Steam Guide. Draft Working Document (Revision B) Revised October 30, 1997.
5. Grant, A., B.K. Henon, and F. Mansfeld. Effects of purge gas purity and chelant passivation on the corrosion resistance of orbitally welded 316L stainless steel tubing. Pharmaceutical Engineering, January/February, March/April, 1997.
6. Henon, B.K. Orbital welding in compliance with the new ASME Bioprocessing Equipment Standard (ASME BPE-97). Pharmaceutical Engineering, January/February, 1999.
7. Henon, B.K. and Angel Brond, Orbital TIG provides right connections for vaccine plant. Welding and Metal Fabrication, April, 1998.
8. FDA Guide to Inspections of High Purity Water Systems
9. An introduction to the ISPE Baseline Guides. Pharmaceutical Engineering. January/February, 2000.
This paper was originally presented at the Latin American Pharmaceutical Show, Centro Costa Salguero, Buenos Aires, Argentina, 28, 29, and 30 March, 2000.
Industries Served
- Aerospace
- Brewery
- Food / Dairy / Beverage
- Fossil
- Heat Exchanger Manufacturing
- Nuclear
- Offshore
- Petrochemical
- Pharmaceutical / Biotechnology / Medical
- A Guide to Codes and Standards
- ASME BPE 1997 Standard
- Capturing Data Electronically For Quality Assurance
- Designing a CGMP Bioprocess Equipment Manufacturing Facility
- Effects of Purge Gas Purity
- Fiocruz Pharmaceutical Plant
- Improvements in Installation Practices of Bioprocess Piping Systems
- Installation of Pharmaceutical Process Piping
- Orbital Welding Technology
- Orbital Welding at Pfizer's Facility
- Orbital Welding of Corrosion Resistant Materials
- Orbitally Welded Hygienic Piping System
- Power Generation
- Pulp / Paper
- Semiconductor
- Shipbuilding
- Vessel Manufacturing
- Wastewater Treatment
- One-Of-A-Kind Industries


text:
At least Counsell turns 41 in 2 weeks.
August 5, 2011
Stephen Colbert wants Adam Dunn and Craig Counsell to be tested for performance diminishing drugs
April 12, 2010
Conan O'Brien lands late-night show on TBS. MLB playoffs effected.
In a move that qualifies as a shocker, Conan O'Brien has made a deal to return to television in a new late-night show on cable — not network — television.
The former "Tonight Show" host has agreed to start a new show on TBS, the comedy-oriented cable channel in the Turner network lineup. The show will start in November and play at 11 p.m. weeknights, teamed with that network's other late-night show, hosted by George Lopez. That show, now at 11, will slide to midnight. …
TBS also promised "the biggest promotional campaign in television history" for Mr. O'Brien, using some of TBS's most popular properties like the NBA playoffs this spring and the Major League Baseball playoffs next fall.
Oh no. Remember the non-stop 'Frank TV' promos during the MLB playoffs a couple years back?
and now the ugly:
Now Mr. O'Brien will be face to face with the two big stars of late-night in cable, Jon Stewart and Stephen Colbert of Comedy Central.
June 24, 2009
Stephen's Coke Party Protest
That was hilarious!


text:
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text:
Free Rider 4
Game not available yet? Share it to show us you want it!
Earlier version(s) of Free Rider 4 racing game:
Free Rider 2
Create your own racing track. Use the tools to draw the curves and the lines. Once you're done, press the arrow up key and your rider will start moving towards the end of the line.
Free Rider 3
Ride your bike and prove to everyone that you can become the world's best free rider. Just remember that if ever you make a wrong move, your bike will immediately crash.
Future version(s):
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text:
Clinical Trial, Open-label, Randomised, in Order to Compare the Quality of Life for Those VIH+ Patients That Start With Monotherapy on LPV/r Tablets Vs. Triple Therapy With a Boosted Protease Inhibitor (QoLKAMON)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01166477
Recruitment Status : Completed
First Posted : July 21, 2010
Last Update Posted : March 20, 2013
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
|Condition or disease
|HIV Infection
|Drug: Lopinavir and ritonavir Drug: Triple therapy with ritonavir
|Phase 4
|Study Type :
|Interventional (Clinical Trial)
|Actual Enrollment :
|228 participants
|Intervention Model:
|Parallel Assignment
|None (Open Label)
|Primary Purpose:
|Official Title:
|Ensayo clínico, Abierto, Aleatorizado Para Comparar la Calidad de Vida de Los Pacientes VIH+ Que Inician Monoterapia Con Comprimidos de LPV/r vs Triple Terapia Que Contenga un IP Potenciado
|Study Start Date :
|January 2010
|Actual Primary Completion Date :
|December 2011
|Actual Study Completion Date :
|December 2011
Active Comparator: Triple therapy
The patients who would be allocated to this arm will continue with their triple therapy treatment, based on any protease inhibitor boosted with ritonavir
Drug: Triple therapy with ritonavir
The patients will continue to take their usual triple therapy, as established in the summary of product characteristics
Experimental: Monotherapy
Those patients allocated to this arm will start to take Kaletra (lopinavir200mg/ritonavir50mg)two tablets bid
Drug: Lopinavir and ritonavir
The patients will take Kaletra (lopinavir200mg/ritonavir50mg)two tablets bid
- Quality of Life comparison for HIV patients that start monotherapy with lopinavir/ritonavir (LPV/r) tablets vs patients with triple therapy which would include any boosted protease inhibitor (PI). [ Time Frame: 24 weeks per patients ]
- Virologic efficacy assessment for HIV patients on monotherapy based on LPV/r tablet vs triple therapy which would include any protease inhibitor [ Time Frame: 24 weeks per patient ]
- Immune response changes assessment for those HIV patients who start monotherapy with LPV/r tablets vs HIV patients on triple therapy which would include any protease inhibitor [ Time Frame: 24 weeks per patients ]
- Patient satisfaction assessment for HIV patients that start monotherapy with LPV/r tablets vs triple therapy which would include any protease inhibitor [ Time Frame: 24 weeks per patient ]
- Treatment adherence assessment for HIV patients who start on LPV/r monotherapy tablets vs triple therapy which include any protease inhibitor [ Time Frame: 24 weeks per patient ]
- Tolerability and safety assessment for the HIV patients who start monotherapy treatment with LPV/r tablets vs triple therapy which would include any protease inhibitor [ Time Frame: 24 weeks ]
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Older Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients infected with HIV-1, documented with a positive HIV-1 antibodies test and/or positive PCR confirmed for HIV-1 RNA.
- Patients on triple antiretroviral therapy with any boosted protease inhibitor.
- Patients with an undetectable viral load, which will be defined as <50 viral RNA copies/mL within the last six months.
- Men or women aged≥18.
- For women with childbearing potential, negative urine pregnancy test during the Screening visit.
- Patients who would have granted a written informed consent prior to any Study-specific screening procedure.
Exclusion Criteria:
- Patients with a written proof of resistance in the accumulated genotype, which would lead to a sensibility loss to lopinavir/ritonavir, or, in case of genotype absence, a documented failure to a protease inhibitor therapy.
- Patients with a CD4 cells nadir CD4 <100 cell/microL.
- Patients who, for any reason, could not be treated with lopinavir/ritonavir.
- Prior medical history of psychiatric disorders, such as depressive syndrome, schizophrenia or psychotic disease.
- Known previous medical history of drug abuse/addiction or alcohol chronic consumption, which in the Investigator's opinion, would be incompatible with his/her Study participation.
- Pregnant or breastfeeding women, or women of childbearing potential who do not use an appropriate contraceptive method, according to the Investigator's opinion.
- Documented past(within four weeks prior to screening) or active current opportunistic infection.
- Patients who, due to severe toxicities related to any of their current HAART compounds, there is a planned discontinuation or modification concerning any of the drugs from their triple therapy.
- Patients for which, according to the Investigator, will have to change their HAART, regardless of the reason, within the next six months.
- Renal disease with creatinine clearance <60 mL/min.
- Concomitant use of Lopinavir/ritonavir contraindicated drugs, such as rifampicin, dihydroergotamine, ergotamine, methylergonovine, cisapride, hypericum perforatum, lovastatin, simvastatin, pimozide, midazolam and triazolam.
- Concomitant use of nephrotoxic or immunosuppressor drugs.
- Patients currently treated with systemic corticosteroids, interleukine-2 or chemotherapy.
- Patients treated with other Investigative Medical Product.
- Patients with acute hepatitis.
- Any disease or condition that, according to the Investigator, would be incompatible with the patient's participation in the Study.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01166477
|Principal Investigator:
|Juan Pasquau, MD
|Sociedad Andaluza de Enfermedades Infecciosas
|Responsible Party:
|Sociedad Andaluza de Enfermedades Infecciosas
|ClinicalTrials.gov Identifier:
|Other Study ID Numbers:
|First Posted:
|July 21, 2010 Key Record Dates
|Last Update Posted:
|March 20, 2013
|Last Verified:
|October 2009
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 Enzyme Inhibitors


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We will be adding more memories over the coming months. In the meantime, if you have memories of the village please add a comment to one of the pages below, register with the site and add your own page or contact Meldreth Local History Group.
Meldreth History > http://www.meldrethhistory.org.uk/
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"Entertaining and informative… I am happy to report that nothing is full of interesting reading." —New Scientist
"Convincing…authoritative . . . tells the story persuasively." —Nature
"Barrow's efforts to relate scientific developments to wider cultural themes must be applauded." –Los Angeles Times Book Review
"Stuffed with wonderful stories. . . . [A] feast of clear thinking and fine writing." —BookPage


text:
In the district, a relatively large proportion of the net sown area is unirrigated, indicating high irrigation demand. Overall, water availability for irrigation in the district (based on ground water development and long-term trends of water level decline) is within the safe limit, enhancing long-term sustainability of solar pumps. The district has a relatively high penetration of banks in rural and semi-rural areas, facilitating higher access to institutional credit for farmers. There is a comparatively low level of farm mechanization, possibly due to low awareness or poor outlook towards progressive technologies amongst the farmers here. The district has a relatively high proportion of small and marginal farmers. The district appears in the group of districts, which are (very) highly vulnerable towards climate change, as per an index constructed by CRIDA.
If you are deploying solar pumps in this district then you can further these policy objectives.


text:
- Status : Released
- Movie Genre : Action, Comedy, Crime,
- Youtube Id : -youtube_id-
- Duration of movie : 107
- Vote Count : 341
- Film Note : -movie_rating-
- Average rate : 5.9
- Original title : The Other Guys
- Languages spoken : English
- Societies of production : Columbia Pictures
- Tagline : When the cops are busy... Our only hope is...
- Release Date of film : 2010-08-06
- Will Ferrell Character (Detective Allen Gamble)
- Mark Wahlberg Character (Detective Terry Hoitz)
- Eva Mendes Character (Sheila Gamble)
- Samuel L. Jackson Character (P.K. Highsmith)
- Dwayne Johnson Character (Christopher Danson)
- Michael Keaton Character (Character)
- Brett Gelman Character (Hal)
- Ray Stevenson Character (Roger Wesley)
- Roy T. Anderson Character (Rasta)
- Larnell Stovall Character (Rasta)
- Steve Coogan Character (David Ershon)
- Rob Riggle Character (Martin)
- Damon Wayans, Jr. Character (Fosse)
- Bobby Cannavale Character (Jimmy)
- Brooke Shields Character (Brooke Shields)
The Other Guys Synopsis:
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Over the past 15 years, VisioSign has been developing and providing communication strategies and information screen systems to major private companies and public institutions. Thanks to their loyalty and satisfaction with our products and professional services that we offer, VisioSign has taken a leading position within this field with more than a 50% market share in Denmark alone.
Today, our information screens are deployed at hospitals, child-care centers, schools and universities in numerous cities, as well as conference centers and production facilities across the country.
See the list of all our main customers
Read, what our customers say about us


text: Log In Calendar of Events Events Log In Don't have an account? If you don't have an account, click the button below to create one. The setup process is easy and only takes a few minutes. Sign up now! Log In User ID * Required Password * Required Forgot Password? Login


text:
The major U.S. Olympic trials are under way through July 2 in preparation for the London 2012 Olympic Games. Live coverage of many events can be found on the NBC Sports Network, and selected videos will appear on NBCSports.com. Here's what you should watch Thursday June 21:
The event: Diving finals, women's 3m synchronized
When: 10 p.m. to 12 a.m. ET, NBC Sports Network
U.S. & World
Where: Weyerhaeuser King County Aquatic Center in Federal Way, Wash.
Ones to watch: Abby Johnston and Kelci Bryant own a slight lead over Kassidy Cook and Christina Loukas going into the 3m synchronized final at the U.S. Olympic diving trials. Johnston and Bryant totaled 637.80 points through the preliminaries and semifinals Sunday on opening night of the eight-day trials.
Abby Johnston, 22, began diving in 2002 and was born in Columbus, Ohio. Previously a gymnast (she had to quit due to a back injury), Johnston is enrolled in a pre-med program and has interned in the brain tumor clinic at Duke Hospital in North Carolina. She partners with Kelci Brant in the synchronized 3m, and the pair placed first at the 2012 USA Diving Winter National Championships and fourth in the same event at the 2012 FINA World Cup.
The youngest of five children, Kelci Bryant, 23, hails from Chatham, Ill. and placed fourth in the synchronized 3m at the 2008 Olympics in Beijing alongside Ariel Rittenhouse (now retired). Bryant is enrolled at the University of Minnesota and her club team is Minnesota Diving.
What happens: The top two finishers in each individual event will go to London.
Read more about the diving trials and about the Olympic diving events.
For broadcast information, NBC 's Olympic website and click on "TV Listings" for your local listings.


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text:
Throughout history, American innovation and entrepreneurship have prompted some of the world's greatest achievements. Today, though, the prospects of providing our children with the same opportunities we've fought for and enjoyed are facing two major threats; a stagnant economy, and the increasingly devastating and costly impacts of climate change.
The challenge is like few others in our history. We must find a new way forward for this great nation, one that safeguards our future and addresses the economic challenges of today. We need a new American Revolution. An American Clean Revolution.
This is our one, real hope for a better future. It means a swift, massive transformation of our economy, powered by clean, plentiful, affordable energy. It is the commonsense road to generating growth, creating prosperity, and ensuring sustainability.
Researchers have shown that a clean energy strategy could deliver GDP gains of US$3 trillion to the US economy. Global business opportunities for US companies are potentially huge: the clean tech market will be worth US$2 trillion by the end of the decade.
Leadership and innovation is not only what built America: it's what will take us forward. The passive acceptance of economic decline through climate change is not the American way. It's time for bold leadership to drive this transformation, revive our economy, and make our country great again.
Find out exactly how America will win US$3 trillion for its economy by downloading the report using the button above, now.


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text:
Federal court hears I.D. case
Because she has a religious objection to Northside Independent School District's new student tracking system, Andrea Hernandez and her father testified in federal court Monday, she should not be transferred to another school for refusing to carry a student I.D. badge.
Hernandez, 15, a sophomore in a science and engineering magnet program at John Jay High School, and her father, Steven Hernandez, each testified that they believe the tracking system — which uses radio frequency identification tags inserted in student badges — is a sign of submission to the Antichrist as described in the Bible's Book of Revelation.
Northside began trying out the RFID technology at two schools this fall. It allows an attendance monitor to locate students at specific areas on campus in real time.
It's a way to maximize state funding, which is partly based on daily attendance, to cope with budget cuts, Northside Superintendent Brian Woods told U.S. District Judge Orlando Garcia. The system allows a more accurate count of which students are at school and could help locate individuals quickly in case of emergencies, Woods said.
Appearing composed and forthright, Andrea testified that wearing the badge would be tantamount to "accepting the Mark of the Beast," which Revelation predicted the Antichrist would try to make people do.
After Andrea refused Northside's offer to remove the RFID chip from her badge, the district ordered her transferred to Taft High School, her regular neighborhood campus. Northside officials said Monday she will be allowed to finish the fall semester at Jay regardless of Garcia's ruling.
Students have generally complied with the requirement to wear their badges, and parental opposition has been limited, officials have said. Andrea said she has not faced much antagonism from classmates for her protest.
"There are some students who are friends that are behind me 110 percent, and there are some who don't agree with me," she said.
Steven Hernandez teared up on the stand after reading a passage from the Bible and explaining how deeply he holds his faith on the issue. He said supporting the program "would compromise our salvation for NISD to make some money."
Andrea told the judge that her educational goals would be harmed if she goes to Taft because she wouldn't be able to take certain classes in pursuit of a career as an interface web designer. Garcia repeatedly asked Andrea and her father why she could not wear the badge with the chip removed. That would be "falling in line with the rest and showing support for the program," Steven Hernandez testified.
After the hearing, when asked who he thought was assuming the role of the Antichrist, Steven Hernandez replied, "In this case, Northside is the Antichrist."
Garcia said he would decide this week on Andrea's request for a permanent injunction to keep her at Jay.
The case focuses only on her situation and not on the RFID program as a whole, attorneys said.
Fvara-orta@ express-news.net


text:
All prices include shipping in the continental US.
-Castaspella -35
-Dekker -30
-Icarius -30
-Karatti -30
-Plundor -30 *SOLD*
-Geldor -30 *TRADED*
-NA He-Man -33 *TRADED*
-Mantenna *SOLD*
-Lord Dactys *SOLD*
-Clamp Champ *SOLD*
-Castle Warrior set (alcove is broken) *SOLD*
All are MOC in mailer. First come first serve. Prices include shipping in the US. Shipping can be combined on for multiple items. Int
-Granamyr (MIB)
-End of Wars Weapons Pak
-Horde Troopers (one or 10, loose or MIB. Don't need all weapons)
As always, if you need something you don't see on the list but want to try me anyway, feel free to PM me. Thanks for your interest.


text: Hi Christine, good to know that you are planning to home-school your niece. I know there are lot of video lectures available on YouTube, but I don't think they have any actual exercises you can download and print. There is one site which I have been using (lernsys.com) that has both video lectures and practice exercises you can print.


text:
In 2018, the Company developed in accordance with its strategic goals and maintained its leading position in terms of proved hydrocarbon reserves among the world's public oil companies.
As of December 31, 2018, Rosneft's proved hydrocarbon reserves under the SEC classification amounted to 41,431 million barrels of oil equivalent (5,597 million toe)*. Hydrocarbon reserves increased by 1,524 mln boe compared to the end of 2017 (202 million toe) or 4%. The audit was conducted by DeGolyer&MacNaughton, which provides for the assessment of reserves by the end of the period of profitable field development.
As a result of 2018 operations, Rosneft's proven hydrocarbon reserves under the SEC classification were estimated as sufficient for 20 years. The replacement factor for proven hydrocarbon reserves under the SEC classification in 2018 amounted to 173%**.
For a number of years Rosneft has been the leader among the largest public international oil and gas companies in terms of proved reserves under the SEC classification and by replacement ratio. At the same time, the Company demonstrates the lowest costs of hydrocarbon exploration and development among international energy companies.
According to the PRMS (Hydrocarbon Resources Management System) classification, DeGolyer&MacNaughton estimated hydrocarbon reserves in the 1P category of 47,045 million barrels of oil equivalent as of December 31 2018. (6,368 million toe), 2P - 84,094 million boe (11,388 million toe), in the 3P category - 121,165 million boe (16,426 million toe).
The increase in the reserves assessment in 2018 was due to the successful geological exploration, commissioning of new field areas, as well as effective work to improve field development in both traditional oil production regions (RN-Yuganskneftegaz, RN-Nyaganneftegaz) and new projects (East Siberian fields).
* - including fuel gas
* - The replacement ratio is calculated in tons of oil equivalent. The replacement ratio in barrels of oil equivalent was 175%.


text:
If you don't own VCDS yet but you're thinking about buying it, ask your questions here.
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text:
Bearish momentum continued on Wall Street today, as ongoing fears over the looming fiscal cliff overshadowed better-than-expected economic reports. The number of Americans applying for jobless benefits fell last week, bucking analyst's expectations for an increase. Meanwhile, the U.S. trade deficit unexpectedly narrowed in September to the lowest level since the end of 2010. Despite the positive reports, investors remain grim over the possibility of a split Congress coming up with a resolution before the automatic round of massive spending cuts and tax hikes are to take effect on January 1st [see also How To Pick The Right ETF Every Time].
Global Market Overview: Stocks Decline On Fiscal Cliff Fears
Investors continued the post-election sell off today, pushing all three major U.S. indexes deeper into negative territory. Tech-heavy Nasdaq (QQQ) came in at the bottom of the barrel, shedding 1.42% during the session. The Dow Jones Industrial Average (DIA) and S&P 500 (SPY) dropped 0.94% and 1.22%, respectively. In Europe, markets gave up earlier gains after a news report indicated that European finance ministers may delay its decision on when to release aid funds for Greece. Asian equities also closed lower: China's Shanghai Composite slid 1.6%, while Japan's Nikkei Stock Average dropped 1.5%.
Bond ETF Roundup
U.S. Treasury priced ticked higher today, recovering yesterday's losses, after a surprisingly strong sale of 30-year bonds. The Treasury Department sold $16 billion 30-year bonds at a lower-than-expected 2.82% yield.
Commodity ETF Roundup
Energy and metal futures traded higher today, with crude oil prices rising above $85 per barrel after suffering it's biggest one-day drop yesterday. Meanwhile, natural gas futures ended slightly higher in a volatile session after a government report showed inventories grew less than expected.
ETF Chart Of The Day #1: LBND
The Invesco PowerShares 3x Long 25+ Year Treasury Bond ETN (LBND) was one of the best performers today, gaining a whopping 4.33% during the session. With a better-than-expected government auction of 30-year bonds, this leveraged ETN gapped significantly higher at the open. LBND inched higher throughout the day, eventually settling at its high of $52.23 a share [see also 30 Years Til Retirement ETFdb Portfolio].
ETF Chart Of The Day #2: GREK
The Global X FTSE Greece 20 ETF (GREK) was one of the worst performers today, shedding an abysmal 6.99% during the session. Following reports of a possible delay of bailout funds to Greece, this ETF gapped significantly lower at the open. GREK slid lower throughout the day, eventually settling at $15.44 a share [see also Euro Free Europe ETFdb Portfolio].
ETF Fun Fact Of The Day
Only five ETFs offer exposure to Whole Foods Market (WFM), which tumbled 5.86% today after the natural-foods supermarket fiscal 2013 forecast missed analyst's expectations. The EcoLogical Strategy ETF (HECO) allocates 5.24% of total assets to the stock, while the Dynamic Food & Beverage Fund (PBJ) gives WFM a 4.96% weighting.
Follow me on Twitter @DPylypczak
[For more ETF analysis, make sure to sign up for our free ETF newsletter or try a free seven day trial to ETFdb Pro]
Disclosure: No positions at time of writing.
Click here to read the original article on ETFdb.com.
Read more posts on ETF Database »


text:
And now for something completely different!
Atahualpa is so flexible that I got a little carried away! I got a LOT of help from Flynn and Juggledad in the beginning. Since then, I have been able to mess things up on my very own. It really is Atahualpa at heart, and I couldn't have done it without that great base.


text:
1. If the products have quality problem, should returns be required. Please contact us for a return authorization.
2. We do not cover any items for damage after use.
3.Since computer screens have chromatic aberration ,especially between CRT screen and LCD screen,
we can not guarantee that the color of our products will be exactly the same with the photos you see.
And the same color but different fabric must has chromatic aberration, please understand.


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Scope of supply: 1x ViaSnap Easy Action Cam, 1x Waterproof Case, 1x handlebar holder, 1x Adapter Clip, 2x Velcro fasteners, adjustable 1x Adapter, 1x USB cable, 1x adapter clip, 1x holder 1x beltShock and scratch resistant camera housing up to 50m Waterproof - Ideal for shooting when motorcycling, mountain biking, skiing, running, etc - The Action Cam can be attached to a helmet for example or handlebar - 2 TFT screenBattery removable and replaceable - White balance adjusted - continuous shooting mode - Exposure setting - Seamless video function - Webcam mode - LED indicator lights - Video Format: mov - Video resolution: 1280x720 = 30fps / VGA; 640x480 30fpsViewing angle: 170
Action Camera Cagiva Raptor 1000 ViaSnap Easy HD YBGHRBNTJ


text:
Grand Hyatt Amman Hotel is a 5 star luxury hotel located in the business and diplomatic district Jabal Amman. Amman city centre is only two kilometers away. The preferred hotel for the discerning business traveler, Grand Hyatt Amman has a link to Zara Expo, Jordan's leading Exhibition and Conference Center. Grand Hyatt Amman hotel in Jordan is just 30 minutes from Amman's airport, Queen Alia International Airport.
The hotel also offers recreational activities such as a fitness centre, swimming pools and a health spa for the well-being of our guests. Grand Hyatt Amman is host to some the finest restaurants in Amman. Grand Hyatt Amman´s restaurants range from Indochine, where the beauty and sensuality of 1930s Vietnam is captured together with the intricate flavours of exotic Asia; the hotel's Italian restaurant, L'Incontro, where Milanese chic is fused with innovative cuisine; and The Grand Café for lavish buffets.


text:
A region named after the charming, quaint historical town in Bordeaux, St-Émilion is situated on the right bank of Bordeaux. It's grapes of choice are Merlot and Cabernet Franc (called Bouchet on the right bank). The region has its own classification system, updated and revised every few years. Two of the hottest chateaux of the area (and the only Premier Grand Cru Classé A) are Chateau Ausone and Chateau Cheval Blanc.
Region: St. Emilon,Brodeaux,France


text:
WASHINGTON, April 10, 2014 — (PRNewswire) — The headquarters of the American Society of Landscape Architects helped Washington, D.C., rank second on the U.S. Environmental Protection Agency's (EPA) 2014 list of the top U.S. cities with the most ENERGY STAR certified buildings.
Cities are ranked on the list by how many buildings earned the prestigious ENERGY STAR in their area last year. ASLA's headquarters was one of 435 ENERGY STAR certified buildings in 2013 that helped Washington, D.C., make the list. To earn EPA's ENERGY STAR, buildings must be more energy efficient than 75 percent of similar buildings across the country.
"We are honored that our headquarters played a key role in Washington, D.C.'s ranking on EPA's Top Cities list this year," said Nancy Somerville, Hon. ASLA, executive vice president and CEO of ASLA. "Environmental stewardship has been a core value of ASLA since its founding in 1899. ASLA is fully committed to sustainable practices through program initiatives and day-to-day operations—including our headquarters. We're proud to be in a city where others are equally committed."
ASLA has participated in EPA's ENERGY STAR certification since 2008, and its headquarters building was ENERGY STAR-certified again in 2013. Among buildings the same size, ASLA's energy performance is in the top 11 percent. ASLA's headquarters employs energy-efficient systems and practices—including a green roof that reduces energy usage by 10 percent in winter months. Sustainability is part of the organization's leadership and staff culture.
ASLA offsets 100 percent of its electricity use by purchasing Green-e Energy certified renewable energy certificates from wind farms in the United States. An automated building management system controls access, lighting, and heating/cooling systems, and puts the building to sleep each night.
ASLA's green roof was designed by Michael Van Valkenburgh Associates, a leading landscape architecture firm. Some key benefits include reduced building heating and cooling costs and reduced stormwater runoff. The green roof reduces energy usage by 10 percent in winter months. It also does not contribute to D.C.'s urban heat island effect as it has been as much as 59 degrees Fahrenheit cooler than conventional black roofs on neighboring buildings.
More than 23,000 buildings across America earned EPA's ENERGY STAR certification in 2013. These buildings saved more than $3.1 billion on utility bills and prevented greenhouse gas emissions equal to the annual electricity used by more than 2.2 million homes.
"Making our nation's buildings more energy efficient is more critical than ever," said Jean Lupinacci, chief of the ENERGY STAR Commercial & Industrial Branch. "Organizations that earn the ENERGY STAR demonstrate how leaders across the country are embracing efforts to protect the environment while also creating financial value."
Commercial buildings that earn EPA's ENERGY STAR must perform in the top 25 percent of similar buildings nationwide, as verified by a professional engineer or a registered architect. ENERGY STAR certified buildings use an average of 35 percent less energy and are responsible for 35 percent fewer greenhouse gas emissions than average buildings. Many types of commercial buildings can earn the ENERGY STAR, including office buildings, K-12 schools, and retail stores.
Products, homes and buildings that earn the ENERGY STAR label prevent greenhouse gas emissions by meeting strict energy efficiency requirements set by the U.S. EPA. In 2013 alone, Americans, with the help of ENERGY STAR, saved an estimated $30 billion on their utility bills and prevented greenhouse gas emissions equal to the annual electricity use of more than 38 million homes. From the first ENERGY STAR qualified computer in 1992, the ENERGY STAR label can now be found on products in more than 70 different categories, with more than 4.5 billion sold. Over 1.5 million new homes and 23,000 commercial buildings and industrial plants have earned the ENERGY STAR label.
For more information about the 2014 ENERGY STAR TOP Cities list, visit www.energystar.gov/TopCities.
For more information about the American Society of Landscape Architects, visit www.asla.org.
For more information about ENERGY STAR, visit www.energystar.gov/buildings.
Follow ASLA on Twitter at @landarchitects
Logo - http://photos.prnewswire.com/prnh/20140325/DC90161LOGO-b
SOURCE American Society of Landscape Architects


text: WELL F-OFF PHOTOBUCKET...If the pics below don't show click the link below to jump to when I started using a far superior product; Smugmug.com. There are pics from this point forward: http://advrider.com/index.php?threads/costa-rica-trippin-with-gr.856426/page-6#post-21951874 I'm done lurking and making incoherent remarks on other's RRs. It is time to share. First, a brief intro into the who, the what, the where, the why and the ADV's to follow… Who I am GRinCR or Greg in Costa Rica. I study, I work, and I wish I had more free time. I am a father, a son and a husband. I am originally from the southern burbs of St Paul, Minnesota. I said nuts to winter in Nov of 2006 and flew the coop to Costa Rica. This was two short years after a study abroad program which brought me here for Jan, Feb and Mar of, you guessed it, 2004. My wife is Ana Yancy, half Panameña and half Costarricense. We have a son Joseph who is our only, for now. What This Thread will be made of many small trips. I seek tranquility, great views, tasty food, good people and epic roads for ADV motorcycling. I will locate peaceful places to camp and comfortable accommodations. I want to find places to explore and basically highlight all I can off the "Gringo Trail". I have many ADVs in the archives and surely ones that have yet to materialize. This RR, like many, may get sidetracked and stray a bit from motos… Chicks! (the wife is starting to understand this is a package deal) Good eats. Booze. Swimming holes. Friendly and inquisitive locals. But in the end it is all about the RIDE and where your ADV can take you! A goal is to keep this to a minimum. Where In and around Costa Rica. Basically as far as a few days of free time can take me. Until, of course, the day comes I graduate to the big boy club and can post in "Ride Reports" without being banned. Why My wife calls it an illness and it is contagious. The only known cure is to ride and it is a temporary fix. So what is my Excuse? Any. There is something on the other side of that horizon. The indirect route is often better. Pavement gets boring. Because you said it can't be done! When Soon grasshopper. But here is a taste of the first RR and most recent, still fresh in the mind from the beginning of Dec. I hope to post tomorrow, but this is Latina America and tomorrow means whenever. Hasta Luego!


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'Two Nights Near Doolin' at Ives
DANBURY -- An assignment to find an Irish story to air as a movie of the week ultimately led to the creation of an original play to be staged this weekend at Ives Concert Park on the Westside Campus of Western Connecticut State University.
Louisa Burns-Bisogno, a professor in the WCSU Department of Writing, Linguistics and Creative Process, explained how "Two Nights Near Doolin" came to be.
"In the early 1980s, I was given an assignment by my producer to find an Irish story for American television," she said. "It was the height of `The Troubles' -- the bloody civil war in the North. I witnessed several tragic events, and many innocents were caught in the crossfire. This folded into a story that I heard while a graduate student at Trinity College, Dublin, in 1990 about an American who went in search of his family history.
"The play's setting came about in the mid-'90s when I was invited to read my paper at the First International Conference on the Irish Diaspora at the University of Cork," Burns-Bisogno said.
"While there, I attended my own `Clancy Clan's annual meeting.' On my way from that event to Cork, I stopped by a little village called Doolin. Located near the famous Cliffs of Moher, Doolin was the center of Irish traditional music and is now a major tourist site. Back then however, musicians would just come down from the hills and `jam.' It was a fabulous experience and I have been there several times."
The resulting play, "Two Nights Near Doolin," will be staged at Ives Concert Park, 43 Lake Ave. Extension in Danbury, on Friday, Saturday and Sunday, July 11 -- 13. Tickets are $15 for adults and $10 for students, plus ticketing fees. A ticket four-pack is available for $40, plus fees. Before the curtain rises on each 8 p.m. performance, there will be traditional Irish dance and music for 30 minutes to fully transport the audience to a pub near Doolin.
Pam McDaniel, a WCSU professor of theater arts, will direct "Doolin." McDaniel brings her own Irish travels to the staging of Burns-Bisogno's play. She spent 10 days there last summer conducting research she believes will add to the authenticity of the performances.
"I went to Ireland on a research grant to attend the Galway Arts Festival and also to spend time in and near Doolin to see the people and places the play is about," McDaniel said. "I interviewed people in pubs about the local tradition of passing musical skills down from one generation to the next, and I heard traditional musicians play. I met families who had operated pubs for six generations and found a prototype for the pub that is the setting for our play."
For tickets or information, visit www.ivesconcertpark.com or www.eventbrite.com/e/two-nights-near-doolin-tickets-7184995515.


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Store Coordinator Merchandising Vaudreuil/Coordonnateur de magasin Marchandisage Vaudreuil
Are you ready to explore career opportunities at TJX Canada and join our team?
TJX Canada is part of The TJX Companies, Inc., the world's leading off-price retailer of apparel and homeware worldwide, and in Canada, our retail chains include Winners, Marshalls and HomeSense.
In the retail business, we move fast. We're always adapting, evolving and innovating. And the fast pace brings variety and challenge, along with many growth opportunities. We operate hundreds of stores in hundreds of cities.
TJX's retail chains include TJ Maxx, Marshalls, HomeGoods and Sierra Trading Post in the United States; TK Maxx in the United Kingdom, Ireland, Germany, Poland, Austria and the Netherlands, as well as HomeSense in the United Kingdom and Ireland; and TK Maxx in Australia.
As a retailer committed to growth, success is always in style at TJX!
Meet Marie.
Marie is a born leader, so we were thrilled when she left her merchandising job in a Montreal boutique to become one of our Merchandise Coordinators. She helps decide which items should move from the backroom onto the sales floor, trains sales associates, and monitors markdowns so our customers always get the best deals. She keeps shoppers looking great by getting the latest styles out in the open.
And she always looks great, too, even when she's sprinting across the store hurdling clothing racks in four-inch spike heels. Don't worry, she only does it after-hours.
This is Marie. She is one of us.
But know this. If you do decide to apply for this position, and we agree that this is the right job for you, you'll be supported by a plethora of internal programs whose only focus is the continued progress of your career. At TJX Canada, we do everything we can to help you achieve your full potential. But we can't do it all ourselves. You'll need to bring the ambition, the motivation, and the drive.
So what do you think? Like Marie, are you one of us?
Now, if you were to come on board as one of our Merchandise Coordinators, we'd ask you to do the following:
- Understand and be knowledgeable of BEST operational standards and monitor your respective zone's performance and execution against these standards
- Provide weekly updates on objectives and identify any issues or opportunities pertaining to merchandise, sales floor, and IBI
- Review weekly MAP and CommPak, and support communication of change to merchandise presentation, IBI, fashion trends, ads, events, etc.
- Assign priorities and provide direction and support in the communication to drive sales and improve merchandise processes
- Develop a plan with our AM of Merchandise to increase sales in underperforming departments and capitalize on high performers
- Work with our AM of Merchandise and our Merchandise Processing Coordinator to determine the priorities for processing and moving new merchandise to the sales floor within set standards
- Support markdown functions, including performing markdowns, monitoring markdown process in zone, etc.
- Train and develop Sales Associates in merchandise-presentation standards, assist in the training and development of Sales Associates, and provide customer service for both internal and external customers
Sounds rather challenging and exciting, right? Let's hope so, because if it sounds easy or boring, there's a good chance this job isn't for you. But if it does sound right for you, here's why we know you'll be able to handle those challenges:
- You have strong knowledge of all merchandise-presentation standards and general knowledge of retail operations, including an understanding of fashion trends, seasonal events, inventory levels, etc.
- Your customer-service skills include effectively and efficiently responding to Associate inquiries, identifying stated and unstated customer needs, building relationships with Associates, resolving any problems that may arise, and referring complex issues to Management
- You have strong communication skills, including verbal, written, and active-listening skills
Success is our favorite outfit! As proud as we are of our past success, it's our future that excites us most. We strive to provide opportunities for growth, recognition and a competitive salary and benefits package. Share our determination to think bolder and bigger and be part of our future. Apply now.
Here at TJX Canada we are an equal opportunity employer committed to the inclusion and accommodation of all individuals. For additional assistance please email firstname.lastname@example.com.


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Confident he was going to show me something spectacular, Aubrey Lindley grinned. Then, he carefully unwrapped a sample of very bittersweet chocolate and offered me the small pieces almost reverentially, as if they were sapphires.
The chocolate was made by a local artisan, Steven Lawrence. It was a little "rustic" — a bit rougher in texture and more complex in flavor than traditional chocolate —and sublime.
With about a dozen artisanal chocolate shops, you'd think Portland, Ore., needs a new one as much as it needs more rain. But Jesse Manis's and Mr. Lindley's shop, Cacao, where chocolate prêt-à-porter meets chocolate haute couture just outside the Pearl District, is getting rave reviews. Recently, Hedi Slimane, a French fashion designer, stopped in. He praised the drinking chocolate. The next day he returned for more. Lovers of French chocolates, Jesse and Aubrey considered this high praise.
Mr. Manis spent 10 years immersed in chocolate working for Fran's, a Seattle chocolatier. The chocolate bug rubbed off on Mr. Lindley, and the two opened their shop last September. The walls of the spacious store (kept at 66 degrees to preserve the goods), are painted in soothing colors — '50s-ish sea foam and milk chocolate. Cafe tables are scattered in front. There cocoa fiends, like Mr. Slimane, can sample one of the three kinds of drinking chocolate ($2 a shot). The chocolate with chili had a particularly fine kick.
One mission of the store is to bring respect to the chocolate bar. It offers a selection from up to 35 producers of the world's best. Eyes are drawn, for instance, to the Easter-egg-colored pyramidal packages of Pralus bars from France ($48 for a collection of 10).
Confections like truffles, caramels and pralines are displayed like pinned butterflies in a glass case. Try the chocolate-covered ginger discs from Fran's, or the fig and fennel truffles, from Theo's, also in Seattle, both from $2 a piece.
Cacao, 414 SW 13th Avenue, Portland, Ore., (503) 241-0656; www.cacaodrinkchocolate.com.


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Yelp is a review site that was started in 2004 to help people find information on local businesses, since its inception it has grown by leaps and bounds. In addition to being a business review site, Yelp has information on events, special offers, business lists and is moving into the social networking arena with the ability to add friends and talk with other Yelpers. According to Yelp and Compete.com Yelp has tens of million of visitors a month and Yelpers have written over 9 million local reviews, over 85% of them rating a business 3 stars or higher.
As a business owner, Yelp is great way to build exposure, monitor public opinion of your brand, and research what your local community wants from a business in your industry. Yelp is free to use and post your business on, the only thing you need is time and a little ingenuity.
Let's look at some ways you can use Yelp for your business marketing needs:
1. Join Yelp & Write Reviews (yelp.com)
Just like Facebook it is important to have a personal profile, be active in the community, and then grow from there.
- Create a profile and keep your branding consistent with the profiles you have on Facebook, Twitter, MySpace, Youtube, LinkedIn, Flickr, etc.
- Use the interests area to link to your website, blog, and other social profiles
- Start reviewing your favorite businesses, be honest and fair, your reviews should create value for the readers.
- Review new businesses you come into contact with, be honest but try not to be too complimentary or too harsh – that could come back on you in a negative way.
- Let businesses know when you review them, if they do not see it and respond to your review, then bring it to the business' attention. If your target market is the other businesses this may open a door for you that was previously closed and help you gain more clients.
2. Put your Business Profile on Yelp (biz.yelp.com)
After you have your profile up then you should create a profile for your business. It is best to have your business profile attached to an active Yelp profile, this shows visitors that you are an active participant on Yelp and that you will be there to see their review.
- Keep track of your reviews
- Respond back to the reviewers
- Add recommendations of other businesses to your clients
3. Post Discounts and Announcements
Yelp sends out a weekly email news blast to their users, by posting a company announcement, great discount, and/or an event you have an opportunity of being included in their newsletter and/or on the Yelp site itself. Your discounts may pop up on the users profile pages if they are in your area.
- Discounts should be significant, unique, and specifically targeted at Yelpers.
- Post announcements for company anniversaries, press releases, media pieces, expansion, etc.
- If you are hosting an event or attending an event Yelp gives you 140 characters to announce it. Give it a catchy title, a little grabber sentence and shortened url to get more information.
4. Ask for Reviews from your Clients
In February 2010, according to Compete.com Yelp had 24.4 million unique visitors and 47.4 million visitors overall. When you get a review on Yelp this gives your business a nice front page link on the search engines.
- Add your Yelp business listing to your email signature.
- Ask for reviews from your email database in your email newsletter.
- Ask for reviews from your clients (best time to get a good review is during the transaction!).
- Let people in your online communities know that you have a business profile on Yelp that will encourage them to connect and possibly give you a review.
- Put your Yelp business profile on your website and blog.
4. Build a Network on Yelp
Yelp is a review site but is also a social community and you can build a large influential community on Yelp that will help grow your brand and get exposure for your business.
- Look at who is reviewing local businesses and ask them to become a "friend".
- Look in the talk area to find the most active Yelpers near you, talk to and friend them.
- Send a compliment when you see a great review. At the bottom of the reviewer's review there is a button that will let you send a variety of compliment messages.
5. Create Events on Yelp (yelp.com/events)
Yelp has an events section that will give a full page to an event that you post from your personal profile. This is not available in all cities but it is growing and will hopefully be everywhere soon.
- Add events you are hosting
- Add events you are sponsoring, contributing to, speaking at, and/or exhibiting at
- Add events that you are attending
6. Use the updated iPhone App to Check-In
Yelp has updated their iPhone app to allow you to check in like the users of Foursquare, Gowalla, and Whrrl. Yelp is hoping to capitalize on the popularity of these location based services/communities with their own check-in feature. It is surprising that they did not do this sooner but at least they are getting up to speed now. They just need to make this available through their mobile site and Droid app.
- Check-in to your business to bring exposure to it
- Check-in when you are out and about, it only takes a minute but will build ongoing and far reaching exposure within the Yelp community
7. Link Your Yelps with your Twitter and Facebook Profiles
Yelp will now let you tweet and update Facebook when you post a Yelp review, this will get you more visibility on and off Yelp. You probably have some Yelpers in your online communities – the trick is finding them, so let people know you are there and active.
With these seven steps you will be able to get some great visibility for your brand and business.


text: The DataGrid widget supports deferred row selection. When it is enabled, the DataGrid does not make requests for data until this is demanded from the API. In this demo, data is loaded when the jQuery Deferred object returned by the getSelectedRowsData() method is resolved. To specify initially selected rows, the selectionFilter option is used. Use deferred selection mode when working with a huge amount of remote data.


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Dale Carnegie for Executives
This unique programme brings together 5 elements of Dale Carnegie's approach to training and development, tailored for the C-Suite and similar, to enable you to engage, empower and enable others to achieve high levels of performance.
Czego się nauczysz?
Starting with an Executive 360 degree feedback report, you will get feedback from 10 people above, around and below you to help you understand how your leadership is perceived and the impact it has on others. Following the completion of the report there will be 2 days training on High Impact Communications, as well as a personal coaching session
Dlaczego chcesz się tego nauczyć?
In order to continually develop your business and your people you need to develop yourself as well. This programme will give you the skills to create a more engaging workplace culture. Dale Carnegie for Executives will help you develop the art of emotional connection and high impact communication so that you're people don't just hear what you're saying - they feel it!
Jak ci to pomoże?
By implementing this new level of communication with into your everyday day engagement with other stakeholders inside and outside your organisation, you will be able to sell your ideas with conviction in a manner that builds trust and credibility.


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