The terminology and classification system for the reporting of cervical smears is currently under review. However, evidence on which to base the reporting of atypical cervical glandular cells is lacking. This audit of glandular atypia reporting in cervical smears provides evidence to support a three‐tier sub‐classification system for cervical glandular atypia. The three sub‐classifications are distinct with respect to their positive predictive values and to the cell type of the abnormality as confirmed by histology and therefore relate to further clinical investigation.


Significance X-rays used to collect crystallographic data can change the redox states of transition metals utilized by many biological systems including metalloproteins. This disadvantage has been harnessed to drive a complex chemical reaction requiring the delivery of an electron to the active site and recording the structural changes accompanying catalysis, providing a real-time structural movie of an enzymatic reaction, which has been a dream of enzymologists for decades. By coupling the multiple-structures from one crystal technique with single-crystal and solution optical spectroscopy, we show that the electron transfer between the electron accepting type-1 Cu and catalytic type-2 Cu redox centers is gated in a recently characterized copper nitrite reductase. This combined structural/spectroscopic approach is applicable to many complex redox biological systems.


Metal hydrides were one kind of the high performance materials applied widely at energy-saving aspects in recent years.In this paper the work principle is described and their applications of metal hydride based heat-power transforming system,such as thermal engine,hydrogen compressor and water pump etc.,are summarized.The main problems existed are low capacity of hydrogen storage,poor anti-poison,poor ability of heat and mass transfer of reactor and low efficiency.Moreover,the prospect for further investigation is presented.


The invention relates to a connection device (30) for at least one system (20, 26, 28, 44, 49) which can be electrically connected to a power supply network (8, 10, 12, 14, 14.1, 14.2), comprising at least one control signal input (32) Receiving a control signal from a central controller (36, 40), the control signal being at least one switch-on command, the switcher (30) comprising at least one switch delay means (52) arranged to determine a switch delay time period, the switch delay time period being a random time period, and the connection device (30) is set up, producing an electrically conductive connection between the system (20, 26, 28, 44, 49) and the power supply network (8, 10, 12, 14, 14.1, 14.2) upon receipt of the connection command only after To effect expiration of the particular Zuschaltverzogerungszeitspanne.


Components on console are usually arranged by manual layout according to ergonomics standards and experiences in nuclear power plant. It is hard to balance many criterions, for it depends much on designer's judgments and preferences. This method leads to a random layout results. Particle swarm optimization is a solution to complex optimization problems with constraints, and has been applied successfully in layout and optimization fields. Fitness function was structured according to the evaluating indicators which include operation frequency and order and relationships between individuals. The optimization objective was evaluated by the hand moving distance. This method could be adopted to optimize the layout of components on human-machine interface in order to ensure safety and efficiency of the system. The troubles of subjective feelings and randomness are avoided. An example of 13 components is implemented to show the layout procedure.


Abstract Introduction The underlying pathophysiology of Post-COVID-19 syndrome remains unknown, but increased cardiometabolic demand and state of mitochondrial dysfunction have emerged as candidate mechanisms. Cardiovascular magnetic resonance (CMR) provides insight into pathophysiological mechanisms underlying cardiovascular disease and 31-phosphorus magnetic resonance spectroscopy (31P-MRS) allows non-invasive assessment of the myocardial energetic state. Purpose We sought to assess whether Post-COVID-19 syndrome is associated with abnormalities of myocardial structure, function, perfusion and tissue characteristics or energetic derangement. Methods Prospective case-control study. A total of 20 patients with a clinical diagnosis of Post-COVID-19 syndrome (seropositive) and no prior underlying cardiovascular disease (CVD) and ten matching controls underwent 31P-MRS and CMR at 3T at a single time point. (Figure 1) All patients had been symptomatic with acute COVID-19, but none required hospital admission. Results Between the Post-COVID-19 syndrome patients and matched contemporary controls there were no differences in myocardial energetics (phosphocreatine to ATP ratio), in cardiac structure (biventricular volumes, left ventricular mass), function (biventricular ejection fractions, global longitudinal strain), tissue characterization (T1 and extracellular volume [ECV] fraction mapping, late gadolinium enhancement) or perfusion (myocardial rest and stress blood flow, myocardial perfusion reserve). One patient with Post-COVID-19 syndrome showed subepicardial hyperenhancement on the late gadolinium enhancement imaging compatible with prior myocarditis, but no accompanying abnormality in cardiac size, function, perfusion, ECV, T1, T2 mapping or energetics. This patient was excluded from statistical analyses. (Table 1) Conclusion In this study, the overwhelming majority of patients with a clinical Post-COVID-19 syndrome with no prior CVD did not exhibit any abnormalities in myocardial energetics, structure, function, blood flow or tissue characteristics. Funding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Welcome Trust Clinical Career Development Fellowship (221690/Z/20/Z);NIHR-UKRI COVID-19 Rapid Response Rolling Call (COV0254)ESC Training Grant Figure 1. Study design.


Historically, artisanal small-scale gold mining has played a significant role in the livelihood of rural communities, and the socioeconomic development of Ghana as a whole. However, its impact on forest resources and quality of water bodies especially rivers in the country cannot be over-emphasized. In Ghana, there are small-scale miners and the artisanal small-scale miners popularly called "galamsey." The small-scale miners are those who are registered and are issued with license that allows them to operate after a form of orientation and training. The illegal or artisanal small-scale miners (galamsey) are those who operate without permit and are not regulated by any government agency. The illegal miners are mostly unskilled and have no regard for sustainable mining practices. According to Hilson and Potter (2003), Ghana's small-scale gold mining sector comprises registered operators (the "official system") and galamsey (the "unofficial system"). The industry has become a major contributor to national gold production and employer of rural labour force (Ministry of Lands & Natural Resources, 2018). Abstract Artisanal small-scale mining has been part of Ghana's history, but recent public outcry on the devastating impacts of the phenomenon on water bodies, due to expansion in the sector, has led to clamp downs by various governments on the activity. This has called for evaluation of the water quality of the South-western Rivers System, which are smallscale mining endemic areas. Thirty-five river samples were collected in July 2018 and were analyzed for physico-chemical parameters using procedures outlined in the Standard Methods for the Examination of Water and Wastewaters. The results revealed that the rivers are polluted with Fe and Cu, accompanied by very high levels of turbidity (mean = 488 NTU) and total suspended solids (TSS) (mean = 382 mg/L). NH3–N, PO4–P, BOD, and DO levels indicated mild pollution in the waters. Pollution of the rivers is attributable to impacts of artisanal small-scale mining, surface run-off as a result of high intensity rainfall, anthropogenic (indiscriminate waste disposal) and geogenic factors such as dissolution of minerals from the soil zone. It was observed that, if not strictly regulated, turbidity and TSS levels arising mainly from illegal small-scale mining activities could lead to shutdowns of a number of Ghana Water Company


This article analyzes stakeholders' roles in implementing Public-Private Partnerships (PPPs) in the state of Bahia, Brazil. The research encom passed three experiences in the fields of health, sanitation, and sport/culture and it assessed all stages in the life cycle of each PPP, from the early stage of matching the proposal to contract execution, going through the funding and construction stages. The main findings show that the various stakeholder types (deliberative, claimant, controller, and funder) have converging and diverging stake patterns over the PPPs life cycle. In the same vein, survey findings reveal that the various stakeholders seem to be less prepared for the later project stages. Such results contribute to the current debates on applying the stakeholder theory to the public sector domain by providing a prospective view of the working patterns of various stakeholder groups in innovative organizational arrangements such as the PPPs.


Implantation of a biomaterial causes an early and local inflammatory reaction, and regulation of the biological behavior of macrophages under inflammatory conditions caused by biomaterials is imperative for the full realization of their function after being implanted. In recent years, hydrolyzed fish collagen has attracted extensive attention resulting from its biological activity. However, to date, no studies have investigated the anti-inflammatory activity of hydrolyzed fish collagen. The aim of this study is to evaluate the effect of hydrolyzed tilapia fish collagen (HFC) on lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages at the gene and protein level and to elucidate its potential mechanism. The results show that glycine rich in HFC can activate the glycine receptor (GlyR) of macrophages, leading to decreased calcium concentration in macrophages, this decrease inhibits the activation of NF-κB, and then the inhibition of NF-κB further attenuates the inflammatory cytokine gene expression and protein secretion. The current study reveals for the first time that by regulating the biological behavior of the macrophages under an inflammatory state, HFC exhibits specific anti-inflammatory effects. More importantly, the presence of GlyR in RAW264.7 cells is verified for the first time. These findings provide a scientific basis for the future application of HFC in anti-inflammatory biomaterials.


Aim: This study aims to evaluate and compare the efficacy of three rotary NiTi (ProTaper UR, R‐Endo, and MTwo R) and one manual (Hedstrom file) instrument in the removal of a resin‐based root canal obturation material (EndoRez) during root canal retreatment of curved root canals by area and volumetric analysis. Methodology: Forty single‐rooted curved (10°–30°) human mandibular premolars were decoronated to obtain a standardized working length. The canals were prepared using hand ProTaper instruments and obturated using EndoRez sealer and EndoRez Gutta‐percha points. Pretreatment volume analysis of the obturation material was carried out using cone beam computed tomography (CBCT). Samples were divided into four groups (n = 10): Group I ‐ Hedstrom files, Group II ‐ ProTaper UR files, Group III ‐ R‐Endo files, and Group IV ‐ MTwo R files. Total time required to attain the working length (T1) and complete removal of material with the last instrument used (T2) was recorded in seconds. Area and volume fractions of remaining filling were calculated in percentage using AUTOCAD 2000 software and CBCT. Statistical Analysis Used: The results were statistically analyzed using analysis of variance and post hoc tests (Tukey‐HSD). Results: H‐files took maximum amount of time for the entire retreatment procedure followed by ProTaper UR, R‐Endo, and MTwo R with statistically significant difference. ProTaper UR files showed maximum cleaning efficiency (both in terms of area and volume of the remaining filling material) followed by R‐Endo, MTwo R, and H‐files with statistically significant difference. Conclusion: NiTi rotary instruments showed superior performance than hand instruments during retreatment.


Abstract A stack of pellicles has been exposed to the 300 MeV πminus;-meson beam of the 660 MeV proton synchrotron at C.E.R.N., Geneva. The interaction lengths for the production of inelastic interactions and elastic scatterings through projected angles greater than 5°, found by scanning along 140 m of track, are (37.9 ± 2.0) cm and (77.4 ± 5.8) cm respectively compared to the geometrical interaction length of 29.3 cm. By comparison with the optical model the absorption coefficient and change in wave number are (1.53 ± 0.15) 1012 cm−1 and ± (1.35 ± 0.12)1012 cm−1, corresponding to a nuclear potential with a real component of (25 ± 1) MeV (of which the sign is not known), an imaginary component, −(14.1 ± 1.4) MeV and a mean free path for interaction in nuclear matter of (6.5 ± 0.7) 10−13 cm. The differences from the expected values are consistent with a considerable reduction within the nucleus of the cross section for elastic scattering of π-mesons by nucleons.


Ultrasonic degassing in liquid phase which is generated by ultrasonic cavitation using high intensity ultrasound is a method of removing residual gas in liquid phase and is one of the important applications of ultrasonic chemistry.This paper summarizes the theory and application status of ultrasonic degassing in liquid phase,and introduces the main research works and results of ultrasonic degassing technology in the metallurgy field,environment field and chemistry field in a detailed way.At the same time,the paper points out that ultrasonic degassing in liquid phase is a stable,effective and rapid degassing technique free of pollution,and it is the most promising degassing technology at room temperature condition.


In a vector-valued nonuniform multiresolution analysis (VNUMRA, in short), the corresponding translation set may not be a subgroup of , but a spectrum associated with one-dimensional spectral pair. In this work, first, we give necessary and sufficient conditions for a family of functions related to VNUMRA to be an orthonormal system and complete system. We provide algebraic results related to the construction of associated vector-valued wavelets from the given VNUMRA. Finally, we give a sufficient condition for the construction of vector-valued wavelets from a given VNUMRA.


With Yantai section experimental road of Yantai-Qingdao Class I Highway for research object,the strength characteristic of the reflective crack in asphalt overlays was analyzed by the commerce FEM software ABAQUS to provide for structure and material design of asphalt overlays.The stress intensity factor(SIF) of shear type KⅡ controlling the road surface crack shows a tendency to reduce with the increases of thicknesses of asphalt overlays.It is a great influence of asphalt stabilized crushed stone's(ASCS) module to the overlay's crack resistance and SIF would increase by the increase of the module of asphalt overlay.The stress concentration on the crack tip would be eliminated greatly by the existences of holes in the heavy grains asphalt overlays.It contributes to hindering the further development of the crack.


Dear Editor, A recent article reported the useful results of autoantibodies in coronavirus disease 2019 (COVID19).1 We obtained additional results of autoantibodies, especially antinuclear antibody (ANA) tested by the same indirect immunofluorescence assay (IFA), in moderate and critical cases of COVID19. We enrolled 47 hospitalized patients with COVID19 confirmed by realtime polymerase chain reaction (PCR), who were classified as either moderate (31 cases; pneumonia but no need for oxygenation) or critical (16 cases; pneumonia and need for oxygenation or mechanical ventilation therapy or death) based on the severity scoring system.2 ANA and anticyclic citrullinated peptide (CCP) antibody were measured in serum or plasma samples within 3 weeks after PCR confirmation. ANA was evaluated by IFA using ANA HEp2 Test System (ZEUS Scientific), and antiCCP antibody l was measured by chemiluminescent microparticle immunoassay using ARCHITECT (Abbott Laboratories). Table 1 shows the demographics of patients and prevalence of autoantibodies. The total positive rate of ANA was 21.3% (10/47), whereas previous studies have been 33.5% (11/33),1 57.5% (23/40),3 or 50% (10/20).4 Variability in the prevalence could be due to the small sample sizes, different assay methods, and different groups of patients enrolled. The total positive rate of antiCCP antibody was 2.1% (1/47), which was lower than 20% (2/10)5 reported earlier. Pascolini et al. documented 36.3% (4/11) nucleolar and 36.3% (4/11) speckled staining among ANApositive cases.1 Our results revealed the same dominant patterns of 50% (5/10) nucleolar and 30% (3/10) speckled staining. However, the ANA titers were mostly weak (median, 1:40; range, 1:40– 1:640), which were quite different from those of Pascolini et al.1 (median, 1:640; range, 1:160– 1:5120). In our study, 9.1% (1/11) of patients with autoantibodies and 8.3% (3/36) of patients without autoantibodies died. Hence, this finding did not reveal any significant difference between the two groups unlike those of Pascolini et al.,1 which showed more severe prognosis in an autoantibodypositive subgroup than in an autoantibodynegative subgroup; 40% (6/15) died versus 5.5% (1/18) died, p = 0.03. However, all these differences between the two studies should be carefully considered because of the small numbers of patients enrolled in both studies (47 and 33), different group of patients selected (moderate and critical cases vs. cases in general medicine or subintensive care unit), difference of methods in detail, and other variables, which likely impact clinical circumstances of the studies. Moreover, three seroconversion/seroreversion cases were found among 16 patients who were tested on consecutive samples in this study. Two ANA seroreversion cases showed all nucleolar patterns and were found only in the moderate group. One antiCCP antibody seroconversion case was found only in the critical group. Therefore, these findings might indicate different immune responses depending on severity. This study has some limitations due to the small number of patients and the results based on certain severity groups. Our results need to be confirmed by further larger scale studies to define the role of autoantibodies and their association with prognosis in COVID19.


Estimating the manufacturing cost of a machined part is a critical task with high importance to manufacturing firms. Accurate cost estimation is important for cost control, successful bidding for jobs, and maintaining a competitive position in the marketplace. There are three main approaches towards cost estimation: estimation based on past experience (variant cost estimation), estimation based on explicit cost computations, and parametric cost estimation. This paper presents a hybrid cost estimation system for rotational parts that uses a combination of the variant approach and explicit cost calculations. The variant approach is used to retrieve machining parameters from a database of past parameters. The explicit cost calculations are based on the part geometry, the cutting tools available and the machining parameters retrieved. The system presented calculates the time that a part needs to stay on the machine. This time, which includes processing, set-up (chucking and re-chucking) as well as tool changes, is used to find the machining cost.


To investigate the applicability of schema-theoretic notions to young children's comprehension of textually explicit and inferrable information, slightly above-average second grade readers with strong and weak schemata for knowledge about spiders read a passage about spiders and answered wh-questions tapping both explicitly stated information and knowledge that necessarily had to be inferred from the text. Main effects were found for strength of prior knowledge (p < .01), and question type (p < .01). Simple effects tests indicated a significant prior knowledge effect on the inferrable knowledge (p < .025) but not on explicitly stated information. A follow-up study was conducted to verify the fact that the question type effect was not due to the chance allocation of inherently easier questions to one of the two question types. We found a reliable decrease in question difficulty attributable to cueing prepositional relations explicitly in the text (p < .01). These data were interpreted as supporting and extending the arguments emerging from various "schema theories".


64 Abstract— Cryogenic Engineering is often faced with the problem of separating a gas mixture or removing undesirable components from a gas stream to be used in a liquefier or in a refrigerator. Pressure Swing Adsorption (PSA) has revolutionized the gas purification and separation system. PSA is a technology used to separate some gas species from a mixture of gases under pressure according to the species molecular characteristics and affinity for an adsorbent material. Research and developmental work on various PSA systems are going on around the globe. The present paper is a state of art report on the various aspects of PSA system towards production of pure oxygen and nitrogen for their eventual liquefaction towards the various cryogenic applications. The paper also highlights advantages and disadvantages of PSA method over membrane and cryogenic separation.


This research aims to identify the student's error in the completion of real analysis using Newman Error Analysis (NEA). The type of research is qualitative descriptive. Which research subjects were 22 students of the mathematics education study program of Universitas Negeri Gorontalo at VI semesters in the 2020/2021 academic year. Data-collection techniques using written tests and interviews. Data is analyzed with reduction, presentation, and drawing conclusion. The result of the study found 4 errors made by students in answering a problem based on NEA: (1) reading, (2) comprehension, (3) transformation, (4) and process skills. This identification can be used by lecturers teaching real analysis to consider supporting the courses and designing learning systems to minimize student errors in solving problems.


In this paper, an automatic music transcription (AMT) algorithm based on a supervised non-negative matrix decomposition (NMD) is discussed. In particular, a novel approach for enhancing the sparsity of the solution is proposed. It consists of a two-step processing in which the NMD is solved joining a <inline-formula> <tex-math notation="LaTeX">$\ell _2$</tex-math></inline-formula> regularization and a threshold filtering. In the first step, the NMD is performed with the <inline-formula><tex-math notation="LaTeX">$\ell _2$</tex-math></inline-formula> regularization in order to get an overall selection of the notes most likely appearing in the monotimbral musical excerpt. In the second step, a threshold filtering followed by another <inline-formula><tex-math notation="LaTeX"> $\ell _2$</tex-math></inline-formula> regularized NMD are repeatedly performed in order to progressively reduce the dictionary matrix and to refine the notes transcription. Furthermore, a user-oriented instrument learning procedure has been conceived and proposed. The proposed AMT system has been tested upon the dataset collected by the LabROSA laboratories considering the transcription of three different pianos. Moreover, it has been validated through a comparison with a regularized NMD and with three open source AMT software. The results prove the effectiveness of the proposed two-step processing in enhancing the sparsity of the solution and in improving the transcription accuracy. Moreover, the proposed system shows promising performance in both multi-F0 and note tracking tasks, obtaining better transcription accuracy than the competing algorithms in most tests.


In order to reduce the input noise level,and detect the corona discharge from high and ultra-high voltage transmission lines in remote distance in the natural environment,a corona discharge experiments platform in laboratory environment was built to observe the characteristics of corona discharge signal,which include wide distribution of frequency,small signal amplitude and strong randomness. The noise and corona signal level was tested near the ultra-high voltage line with strong discharge in the natural environment. The maximum signal-to-noise ratio band was found,which is 200~300MHz. On this basis,a high gain helical antenna with a center frequency of 250MHz was simulated and designed. According to the simulation parameters an actual production of the helical antenna was made,which consistent with the simulation,and successfully detected the corona discharge signal about 140 meters away in the experimental environment. The design and development of this antenna laid a foundation for further study of the long-range detection of the corona discharge from high and ultra-high voltage transmission lines. The characteristics of corona discharge signal and the detection method has important reference value to researchers in related fields.


Background: Pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin (free β-hCG) as valuable biochemical biomarkers are used to screen down syndrome, Edwards syndrome, and Patau syndrome in the first trimester of pregnancy. Closed immunoassay analyzers are regarded as sophisticated platforms to measure biochemical biomarkers. This study compared the performance of three chemiluminescence analyzers when used for combined screening.Methods: The present cross-sectional study was conducted on 371 pregnant women within the age range of 20-47 years during 11+0 to 13+6 weeks of pregnancy referring to Dena laboratory in Tehran, Iran, during July 2018 and August 2018 using random selection. The biochemical biomarkers of PAPP-A and free β-hCG were assayed on Cobas, Immulite, and Maglumi analyzers. Benetech software as a commercial screening software was used to calculate the risks of trisomy 21 (T21), trisomy 18 (T18), and trisomy 13 (T13). Deming regression, nonparametric spearman analysis, analysis of variance, and Chi-square test were performed to analyze the data.Results: For the screening population, although the three systems well correlated to PAPP-A and free β-hCG, the values of Maglumi were slightly higher than those reported for Cobas and Immulite. The multiples of the median (MoM) of PAPP-A and free β-hCG had a significant correlation on three platforms. There were no significant differences between the calculated risks of T21, T18, and T13 on the three systems. The sensitivity for all systems was reported as 50%. In addition, specificity and negative predictive value (NPV) were higher than 99% and 95%, respectively. Positive predictive value (PPV) was reported as less than 50%.Conclusion: The obtained results of the present study demonstrated that there were significant correlations between three different systems in terms of PAPP-A and free β-hCG values and MoMs. The sensitivity of all systems for all trisomies was 50%; however, the specificity of all systems was almost the same. The best PPV and NPV for T21 were on Cobas, Immulite, and Maglumi, respectively. The PPV and NPV of all systems for T18/13 were almost the same.


Background:
 Payment reform efforts have sought to minimize the use of skilled nursing facilities (SNF) after coronary artery bypass grafting (CABG). Little is known about the characteristics and long-term consequences of CABG patients that are discharged to SNF. The purpose of this study was to identify clinical predictors and long-term outcomes associated with SNF use after isolated CABG.

 Methods and Results:
 Clinical data from the Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative were linked to Medicare fee-for-service claims for 8280 Michigan residents undergoing isolated CABG that had no prior SNF use and were discharged alive between 7/1/2012-12/31/2018. A total of 1876 patients (22.7%) had any SNF use identified in claims within one year of discharge with a mean of 27.1 SNF days (SD=30.2). Mean Society of Thoracic Surgeons calculated preoperative risk of mortality was higher for SNF users compared to non-users (3.6% vs 2.0%, p<0.001). Among the 2471 patients with a five-meter walk test, SNF users had a significantly longer five-meter walk time (7.4 vs 6.0 seconds, p<0.001). Multivariable logistic regression identified several factors associated with SNF use, including female sex, older age, non-white race, urgent admission, and the presence of comorbid conditions and major operative morbidity. Long-term survival was significantly worse for SNF users (log-rank test p<0.001) with Kaplan-Meier estimated 5-year survival at 66% versus 86% for non-SNF users (Figure). Even after risk adjustment, hazard ratio of mortality associated with SNF use was 2.04 (95% CI: 1.81-2.29, p<0.001).

 Conclusions:
 One in five isolated CABG patients in Michigan used SNF within a year of discharge and represented a demographically and clinically distinct population of patients with worse long-term survival. Efforts to reduce SNF use following CABG could result in serious unintended effects on outcomes in this at-risk population.


Compounds with high bioactive are commonly used as a nutritional approach for accelerating muscle damage recovery after strenuous exercise. There are still inconsistent results of post-exercise antioxidant supplementation on the circulating muscle damage biomarker. This study aimed to examine the effect of post-exercise Curcuma extract supplementation in ice cream on muscle damage and inflammatory markers in amateur soccer players. Male amateur soccer athletes (aged 14 – 18 years) participated in a randomized double-blind placebo-controlled study under two conditions: control group (n = 10) and treatment group (n = 10). The treatment group was treated with Curcuma extract ice cream (250 mg/100 g) for 21 days. Blood samples were drawn before training, considered baseline, and 3 h after training on day 21. The level of creatine kinase, IL-6, haemoglobin (Hb), and lactic acid were quantified. There was a significant decrease in creatine kinase change in the treatment group compared to the control group (p <0.05). No change in IL-6 and Hb levels in the treatment group. Lactic acid decreased by 16.3% from baseline in the treatment group (p <0.05). Curcuma extract ice cream potentiates to ameliorate exercise-induced muscle damage.


Open Access In modern clinical practice, combination fixed - dose tablets have become a baseline for effective therapy in many clinical conditions. The Hydrochlorothiazide (Hctz) (12.5mg) / Lisinopril (Lis) (10 mg) tablet is a combination drug for treatment of hypertension. In this study, the tablets were prepared by wet granulation method and characterized in terms of weight variation, hardness, friability, disintegration time, dissolution and stability. A high-performance liquid-chromatographic method (HPLC) was used to assay Hctz and Lis in the prepared tablets. Amongst different formulations, WG14 was found to be the best for product development based on both physicochemical and stability results. Pharmaceutical characteristics of the tablets were compared with the Innovator tablet 1A-Pharma (Germany).


Introduction Several studies have proved the relationship between pesticide exposure with low birth weight. But recent new studies result there is no relationshipship between pesticide exposure with low birth weight. Berastagi is countryside area, so it has a higher incidence pesticide exposure. The purpose of this study is to analyze the relationship between pesticide exposure with low birth weight in Berastagi area. Methods This is an analytical study with case control design. Samples used in this study are 42 people from Berastagi area. The data was collected through primary and secondary data. Primary data was taken from Kebidanan Kita which is about the babies who were born less than 2500 gram. The secondary data was collected through questionnaires to measure pesticide exposure. Data was analyzed using Chi Square with 95% significance level (p<0.05). Results The study showed that there was non a non-significant relationship between low birth weight with :direct participation of pregnant woman in pesticide spray(p=0,079), usage of personal protective equipment(p=1), the existence of pesticide inside home(p=1) participation in mixing and involvement in pesticide spraying location (p=0,078). Discussion Pesticide exposure and low birth weight in this study has a nonsignificant relationship in Berastagi area. It is because of system imun mechanism. Future studies using a more specific data of individual exposure to pesticide are required. Key word : pesticide exposure, low birth weight. Universitas Sumatera Utara


Heat balance computation of marine engine systems is related to the normal operation of various equipments such as the main engines,generators,air-conditioning units,cooling units,air compressors,intermediate shaft bearings and the design selection of cooling pumps and coolers.Heat balance computation of marine central cooling system is very complicated,featuring low efficiency due to manual calculation and easy to make mistakes.Based on the theoretical computation of global heat balance of the ship central air-conditioning system,the numerical simulation program is developed according to the basic principles of thermodynamics.Practice has proven that the program is effective in helping with design computation and equipment selection.


This classroom action research aims to improve the economics learning outcomes of Inflation material in class XI IPS-2 SMAN 1 Cariu Bogor Regency through the application of discovery learning learning models. The research method used is classroom action research with four basic interrelated and continuous stages, namely Planning (Plan), Action (Action), Observation (observation), Reflection (reflection) which is designed in 2 cycles. The subjects of this study were students of class XI IPS 2 for the 2018/2019 academic year at SMAN 1 Cariu, Bogor Regency. The number of research subjects was 29 students consisting of 10 sons and 19 daughters. The results of the study concluded 1) There was an increase in economic learning outcomes on inflation material after being given a discovery learning model to class XI IPS-2 students of SMAN 1 Cariu, Bogor Regency. This can be proven by the acquisition of an average pre-cycle score of 68.8 with 44.8% completeness, increasing to 75.2 in the first cycle with 65.5% completeness, and increasing again in the second cycle with an average value of 78.4 and learning completeness 93.1%. Thus the research has been achieved or has fulfilled the completeness of learning. 2) There is an increase in student learning activities. This is evidenced by the level of student learning activity which includes aspects of activeness, attention, discipline and assignments, which have a fairly more dominant score than a score of less so that student learning activity in the first cycle is sufficient category, then in Cycle II it is known that the level of student learning activity who has a good score is more dominant compared to other scores so that student learning activity in cycle II is in good category.


Abstract Alzheimer's is a chronic disease that is often times described by a stages model of progression. This study uses qualitative analyses to explore the experiences of Alzheimer's caregivers. Through this study, stages of caregiving emerge including early, middle, late, and bereavement stages. Through the caregivers' experiences, two additional themes became apparent: spirituality and meaning-making. All but eight of the caregivers mention a positive or negative expression or experience related to spirituality, whether religious or secular in nature. Of the 45 caregivers, twenty-four mention positive and eleven mention negative experiences with their faith, church community, or their spirituality. Findings support the incorporation of using the stages model when working with caregivers and to include spirituality to promote a more satisfying caregiving experience. Recommendations are given to encourage spiritual leaders and practitioners to include spiritual beliefs, faith, or church community in assisting current or potential caregivers.


This article introduces the application of PLC in coal preparation control system.The cntralized control system uses 90-70 series PLC made by CE Comp.,the main control console adopts PAC System RX7i controllers,PC configuration software uses ifix3.5 which has a good system compatibility and human-computer interface.Practice proved that using PLC can raise the level of automation,reduce the staff work strength and ensure the safe and reliable operation of coal preparation,and achieve good economic and social benefits.


l:4-Dimethoxybenzene crystallizes in the space group Pbca with four centro-syrmnetrical molecules per unit cell. A quantitative X-ray investigation, based on visual intensity measurements of about 170 reflexions from crystallographically different planes in the axial zones, has led to a complete determination of the structure, and the results have been refined by double Fourier projections on the planes (100) and (010). The co-ordinates of all the atoms are given. The methyl groups lie in the plane of the ring, and the following bond lengths have been found: C(1)-C(2) = 1.36 A., C(2)-C(3) = 1.37 A., C(3)-C(1') = 1.44 A. (all in the benzene ring) ; C(1)-O = 1.36 A.; O-C(CHa)= 1.35 A., all _+ 0.02 A. The valency angle of oxygen is 121 ___ 2 °. Some of these results are rather unexpected, and though some brief comments are made, detailed consideration is withheld pending their confirmation by the study of other similar compounds.


Background: Lipoprotein lipase (LPL) polymorphisms were suggested to be the risk factor for ischemic stroke (IS). However, controversial results were obtained. Our objective was to investigate the association of LPL polymorphisms at Ser447Ter, HindIII (+/−), and PvuII (+/−) with IS risk. Methods: Literatures search were carried out on databases: PubMed, Web of science, the Cochrane database of system reviews, Chinese National Knowledge Infrastructure, and Embase. Pooled odds ratio (OR) with 95% confidence interval (CI) was calculated to detect the relationship between LPL polymorphisms and the risk of IS. Results: No significant association was detected between LPL Ser447Ter and IS in allelic, dominant, or recessive models (P > .05). Significant lower frequencies of allelic and dominant models of LPL HindIII (+/−) and PvuII (+/−) in cases were detected (HindIII (+/−): allelic model: P = .0002, OR[95%CI] = 0.80 [0.71, 0.90]; dominant model: P = 0.003, OR[95%CI] = 0.80 [0.69, 0.92]; PvuII (+/−): allelic model: P < 0.0001, OR[95%CI] = 0.75[0.65–0.86]; dominant model: P = 0.02, OR[95%CI] = 0.67[0.48–0.93]). And the recessive model of PvuII (+/−) was significantly associated with the IS risk (P = .01, OR[95%CI] = .71[0.55–0.93]). Subgroup analysis stratified by ethnicity showed that the frequencies of allelic, dominant, and recessive models of HindIII (+/−), as well as dominant model of PvuII (+/−) were significant lower in Asian cases (HindIII (+/−): allelic model: P < .00001, OR[95%CI] = 0.69 [0.59, 0.79]; dominant model: P < .0001, OR[95%CI] = 0.69 [0.58, 0.83]; recessive model: P = .005, OR[95%CI] = 0.66 [0.50, 0.89]; PvuII (+/−): dominant model: P = .0008, OR[95%CI] = 0.66 [0.51–0.84]), but not in Caucasian cases (P > .05). In addition, the frequencies of allelic and recessive models of PvuII (+/−) significantly decreased in Caucasian cases (P < .05). Conclusion: the HindIII (+/−) and PvuII (+/−), but not the Ser447Ter might be the protective factors for IS.


To the Editor: Gastric-type endocervical adenocarcinoma (G-ECA) represents a rare and distinct subtype of endocervical neoplasia with aggressive behavior and pathogenesis independent of human papilloma virus (HPV) infection.1 G-ECA with upward extension into the endometrium has been previously mentioned in reported series. Indeed, we have observed G-ECA presenting with abnormal uterine bleeding, mimicking a primary endometrial disorder, and being misdiagnosed as low-grade endometrial carcinoma in endometrial biopsy. Given the importance of this potential pitfall, we hence describe a series of 5 G-ECA cases recently diagnosed at our institution, all presenting with uterine abnormalities initially suspected to represent endometrial neoplasia. The clinical and histopathologic features of the series are summarized in Table 1. Three of 5 patients (cases 1 to 3) presented with postmenopausal bleeding, presumed to represent endometrial hyperplasia or carcinoma by the treating physician. All 3 patients underwent endometrial curettage and/ or polypectomy. At the time of endometrial sampling, the endocervix was described as normal in case 2, whereas in cases 1 and 3 the cervix was not explicitly described. Biopsy revealed invasive mucinous adenocarcinoma involving endometrium in the 3 cases; in 1 patient (case 1), the biopsy was initially interpreted as International Federation of Obstetrics and Gynecology grade 1 endometrial endometrioid carcinoma with mucinous differentiation. The remaining 2 patients (cases 4 and 5) presented with atypical glandular cells, no otherwise specified on cervical Pap smear. Patient 4 also had thickened endometrium on ultrasound; she underwent colposcopy and cervical conization, which on pathologic examination contained adenocarcinoma in situ. Patient 5 underwent endometrial biopsy, which was initially interpreted as serous carcinoma. Hysterectomy was subsequently performed in patients 1, 4, and 5, all showing G-ECA involving the cervix and extending into the endometrium. G-ECA was invasive in patients 1 to 4, and in situ only in patient 5. Patients 1 to 3 had pelvic extrauterine tumor extension (parametria, pelvic wall, rectum, and bladder) and extrapelvic metastases (peritoneum and/ or lung). Patients 4 and 5 had disease confined to the uterus. Follow-up information ranged from 1 to 23 months; disease progression despite systemic therapy was observed in patients 1 to 3. Histologic sections of endometrial biopsy and hysterectomy specimens showed a neoplasm characterized by patent glands of varying shapes. Tumor cells had distinct cell borders and contained abundant pale to eosinophilic mucinous cytoplasm. Nuclear atypia ranged from minimal to severe (Fig. 1). The presence of significant nuclear pleomorphism and diffuse mucinous cytoplasm with distinct cell borders suggested the diagnosis of G-ECA. Immunohistochemistry results are shown in Table 2. P16 was either patchy or completely negative. All tumors were negative for estrogen receptor; progesterone receptor showed only focal positivity in case 2. P53 was abnormal in 3 cases (overexpressed in 2, completely absent expression in 1). Malignant cells were also shown to have a CK7/CK20 (3/3 cases) and CDX2 phenotype (4/4 cases). MUC6 was positive in 3/3 tumors (moderate to strong patchy staining). HPV testing by polymerase chain reaction was attempted in case 4, and resulted negative. PMS2 and MSH6 expression was retained in 3/3 cases tested.


The high volatility of the ship price makes the ship investment very risky business. for that reason the tool which can monitor and evaluate the...


Frequency-shifting jamming can be used as a deceptive or blanket jamming technique. But amplitude loss caused by signal mismatch can depress the jamming. The loss may even draw down the detection probability. Therefore, the relationship between the loss and the size of frequency-shifting is deduced and a method based on amplitude compensated modulation is presented to improve the performance of false-targets. Finally, numerical simulations verify the availability of this method.


We present a dynamic decomposition of apparent power in a polyphase network, based on measurements taken within a portion of a single cycle of the ac fundamental. We show that two time samples suffice for a definition that provides an attractive trade-off between computational cost and dynamic performance. The sub-cycle (or near-instantaneous) metrics that we introduce connect the time- and frequency-domain approaches in a natural way, and address the key weaknesses of the existing instantaneous decompositions. Furthermore, our power metrics are amenable to refinements via symmetrical components, thus connecting with concepts commonly used in system protection. We illustrate the sub-cycle decomposition via two polyphase examples: one of conceptual interest, the other an actual industrial voltage sag event.


liberal ideology and market economics. The cool, factual tone that characterises these chapters is particularly successful when charting the origins and development of Renamo and the history of the war, which loomed over every other development in Mozambique from 1981 to 1992. Unfortunately, however, the structure of the book does the analytical reader a disservice. The method of separating out the main themes into different chapters may make for neatness but it does not make for overall understanding. Political and economic developments during the late 1970s and 1980s were shaped as much by regional politics and the war as by the ideology that informed immediate postindependence policies, and it is somewhat misleading to be almost half-way through the book before even discovering that a war took place. Another weakness is that the references are mainly to secondary sources, and this has a cumulatively distancing effect: the human element, in all its untidiness and ups and downs and—all too often in Mozambique—anguish and despair, does not really come through. Mozambique is fertile ground for a 'what if debate. However, by and large the authors do not stick their own necks out, confining themselves to outlining various of the established positions. They do make some tantalising conjectures, as in 'Had the regime been able to achieve the steady improvement in the material well-being of the population while slowly consolidating its grip on society, and had it been left free from meddling and interference from outside, things might well have been different', but they do not use their wealth of material to break new ground. Their prognosis for the future seems to be the equivocal conclusion that neither one path nor the other is likely to be successful. Reading Confronting Leviathan in late 1998 engenders a strange sense of dissonance. On the one hand, its tale of bloodshed and disaster contrasts sharply with the Mozambique of today—a haven of stability compared with many other SADC countries. On the other hand, judicious neutrality sits uneasily with the revelations contained in the recently published report of South Africa's Truth and Reconciliation Commission. The apartheid regime now stands publicly guilty as charged of all and more of the crimes of which it has been accused by Mozambique over the years and, whatever the authors' interpretation of the Leviathan of their title, must surely be seen as the real monster against which Mozambique was pitted.


Ingesting fish contaminated with ciguatoxins (CTXs) originating from epibenthic dinoflagellates causes ciguatera fish poisoning (CFP). CFP occurs mainly in the tropical and subtropical Indo–Pacific region and the Caribbean Sea. Furthermore, it occurs sporadically in Japan, especially in the Ryukyu Islands between Taiwan and Kyushu, Japan. Variola louti is the most frequently implicated fish with a suggested toxin profile, consisting of ciguatoxin-1B and two deoxy congeners. Therefore, using the liquid chromatography–tandem mass spectrometry (LC-MS/MS), we analyzed CTXs in the flesh of 154 individuals from various locations and detected CTXs in 99 specimens (64%). In 65 fish (43%), CTX levels exceeded the Food and Drug Administration (FDA) guidance level (0.01 µg/kg). Furthermore, in four specimens (3%), the guideline level in Japan (>0.18 µg/kg) was met. Additionally, although the highest total CTX level was 0.376 µg/kg, the consumption of 180 g of this specimen was assumed to cause CFP. Moreover, only CTX1B, 52-epi-54-deoxyCTX1B, and 54-deoxyCTX1B were detected, with the relative contribution of the three CTX1B analogs to the total toxin content (35 ± 7.7 (SD)%, 27 ± 8.1%, and 38 ± 5.6%, respectively) being similar to those reported in this region in a decade ago. Subsequently, the consistency of the toxin profile in V. louti was confirmed using many specimens from a wide area. As observed, total CTX levels were correlated with fish sizes, including standard length (r = 0.503, p = 3.08 × 10−11), body weight (r = 0.503, p = 3.01 × 10−11), and estimated age (r = 0.439, p = 3.81 × 10−7) of the specimens. Besides, although no correlation was observed between condition factor (CF) and total CTX levels, a significance difference was observed (p = 0.039) between the groups of skinnier and fattier fish, separated by the median CF (3.04). Results also showed that the CF of four specimens with the highest CTX level (>0.18 µg/kg) ranged between 2.49 and 2.87, and they were skinnier than the average (3.03) and median of all specimens.


Generic delimitations within the Rottboelliastrae Stapf and Coelorachidastrae Clayton (formal name) are revised. Coelorachis Brongn., Hackelochloa O. Ktze, Heteropholis C.E. Hubb., Ratzeburgia Kunth, and Rottboellia formosa R. Br, are to be included in Mnesithea Kunth. Heteropholis cochinchinensis (Lour.) Clayton and its variety chenii (Hsu) Sosef & Koning are varieties of Mnesithea laevis (Retz.) Kunth. Robynsiochloa Jacq.-Felix is to be included in Rottboellia L. f. The necessary new combinations, a list of genera and representative species, and a key to the genera are given. In the Appendix a new species of Rottboellia, R. paradoxa Koning & Sosef, is described from the Philippines. The enigmatic species Rottboellia villosa Poir. is transferred to Schizachyrium villosum (Poir.) Veldk., comb. nov.


Clinical diphtheria is caused by toxin-producing corynebacteria. Three species, Corynebacterium diphtheriae,Corynebacterium ulcerans, and Corynebacterium pseudotuberculosis, have the potential to produce diphtheriatoxin and hence can cause classic respiratory diphtheria. Therefore, it is of critical importance to haveserological methods that are accurate, reproducible, specific, and sensitive.


I first heard of Pierre Teilhard de Chardin, S.J., and his vision before I reached my teens, and I was immediately taken with what I could understand of his vision. I was interested in evolutionary theory and was excited about the way Teilhard proposes that evolution continues into the
future. I wanted to affirm Jesus Christ and to affirm the world, and through Teilhard I came to see how I could affirm both together. I wanted to live the hope which I not only heard in Teilhard's words but which I also saw on his often photographed countenance.

Over time I have been deeply influenced by Teilhard's synthesis, not just in my views but in the way I try to live. The example of Teilhard's commitment to Christ and to the world through him have influenced my own spirituality, and his vision has greatly enhanced the way I undertake ministry in the Christian community and in t he world.

Since I saw so much of value in his world-affirming attitudes, I was pleased eventually to be able to recognize that something of Teilhard's vision had affected the way the Catholic Church has come to view itself and its relationship to the world. Especially in the Pastoral Constitution on the Church in the Modern World, Gaudium et Spes, the Second Vatican Council affirmed an understanding of its need for interaction with the world, of its mission in the world, and even of its ability to learn from the world in a way that bears the mark of Teilhard's perspective.


Abstract : This report summarizes the certification testing of the General Electric Jet Noise Anechoic Test Facility to be used under the subject program. The precision and accuracy of acoustic measurements are evaluated in terms of: anechoic and far-field environment; ambient levels in the chamber; contamination from piping and combustors; contamination from electronic noise floor; variation of the frequency response of the data acquisition and reduction systems; inaccuracies in aerodynamic instrumentation or fluctuations in the jet aero conditions; and precision errors in the air attenuation model due to environmental fluctuations, gradients and measurement inaccuracies. Jet noise measurements from circular conical nozzles are compared with classical referee data.


To constrain seismic anisotropy under and around the Alps in Europe, we study SKS shear-wave splitting from the region densely covered by the AlpArray seismic network. We apply a technique based on measuring the splitting intensity, constraining well both the fast orientation and the splitting delay. 4 years of teleseismic earthquake data were processed automatically (without human intervention), from 724 temporary and permanent broadband stations of the AlpArray deployment including ocean-bottom seismometers. We have obtained an objective image of anisotropic structure in and around the Alpine region, at a spatial resolution that is unprecedented. As in earlier studies, we observe a coherent rotation of fast axes in the western part of the Alpine chain, and a region of homogeneous fast orientation in the central Alps.  The spatial variation of splitting delay times is particularly interesting. On one hand, there is a clear positive correlation with Alpine topography, suggesting that part of the seismic anisotropy (deformation) is caused by the Alpine orogeny. On the other hand, anisotropic strength around the mountain chain shows a distinct contrast between western and eastern Alps. This difference is best explained by the more active mantle flow around the Western Alps. We discuss earlier concepts of Alpine geodynamics in the light of these new observational constraints.


ABSTRACT This editorial on safety evaluation and risk assessment for the human superorganism introduces a series of papers arguing for a fundamental shift in how we approach human health risk assessment. In this series emphasis is placed on the risk of infectious disease. Our 21stst century understanding of human biology is that, as holobionts, we possess a majority of microbial cells and genes. In fact, our microbes fundamentally affect our interactions with the external environment, metabolism, physiology, and risk of both pathology and disease. As holobionts, we require our microbial partners for us to be both complete and healthy. Using the 20th century understanding of human biology, we failed to capture the effects of the microbiome in evaluating health risks. But 21st century risk assessments such as those associated with exposure to specific microbial pathogens need to include the human microbiome. Microbiome status will be central in determining the health risks for both individuals and populations.


Basing on sol- gel method,the poly(lactic acid)(PLA)/TiO2 organic inorganic hybrid material was synthesized from tetrabutyl titanate(TBT)and self- made PLA. FT- IR and XPS results showthat PLA is combined with TiO2 by Ti- O- C. The kinetic clotting time analysis results showthat the anticoagulation property of PLA has been improved because of the introduction of TiO2 and the best effect is for 4wt%TiO2.


Measurements of the nine adiabatic elastic constants of single-crystal forsterite are reported for the temperature range 300–1700 K at ambient pressure. The measured room temperature Cijs and their first temperature derivatives at ambient conditions are generally consistent with previous measurements, which were taken over a narrower temperature range. Slight nonlinear behavior is observed in the temperature dependence of the C11s, C22s, and C33s moduli. The resulting Hill-averaged bulk and rigidity moduli Ks and G are lower at 1700 K than predicted by linear extrapolation of low-temperature data. At 1700 K the new data give Ks = 103.8 ± 1.1 GPa and G = 61.3 ± 0.5 GPa. Isotropic elastic wave velocities have been calculated using the Hill averaging scheme over the range of temperatures measured. At T = 1700 K and ambient pressure we find vp = 7.79 ± 0.04 km s−1 and vs = 4.48 ± 0.03 km s−1. The parameter (∂lnvs/∂lnvp)P is near to 1.2 and independent of temperature. Calculations are presented for elastic properties and other parameters important for the equations of state and anharmonicity of forsterite. Recent high-temperature thermal expansion measurements on a forsterite specimen from the same boule are used in this analysis. Effects of uncertainties in high-temperature thermal expansion data on these parameters have been evaluated and are discussed.


For the first time correcting stochastic control of physiological status of living systems by weak low‐frequency fluctuating magnetic field with 1/f spectrum (1/f MF) is demonstrated experimentally. The correction was observed in all main systems, including cardiovascular, central nervous, immunity systems of experimental animals. Pronounced prophylactic and therapeutic influence of 1/f MF on malignant growth and radiation disease was discovered. Theoretical interpretation of the results obtained is based upon the notion of fundamental role of 1/f fluctuations in homeostasis of living systems.


This paper proposes a successive interference canceller (SIC) with carrier frequency offset (CFO) compensator for uplink transmission in a non-orthogonal multiple access (NOMA)-based coherent PON. We experimentally confirmed SIC's error-free operation when multiplexing 2 ONUs.


The paper focuses on the optimal scheduling of the diesel generators in the oil rig platform for the fuel optimization problem. The Specific Fuel Consumption (SFC) of the Diesel Generator is not properly modeled in the literature. An accurate model of SFC using cubic spline interpolation method is also presented. Optimization of fuel consumption at various loading conditions has been analyzed with efficient use of load scheduling of the diesel generators. The SFC model consists of discrete and non linear equations and hence conventional method fail to provide optimal solution. The Genetic Algorithm (GA) is proposed for the optimum load scheduling of diesel generators of both equal and unequal ratings. A comparison of all the methods is also presented to obtain the probable optimal solution of the problem. It is concluded that proposed SFC model is more accurate and GA gives better results than conventional methods. The proposed schemes can be used in marine power plant design and are equally applicable for any other technology.


The research method applied is based on the verification of theoretical knowledge about traffic and the functioning of ageing people through an experiment. In this experiment the elderly offer their own opinions about the quality and safety of 'sustainably safe' traffic measures. The study method was established to be workable and produced valid statements. It appears that 'sustainably safe' traffic measures currently applied in practice also offer a considerable safety improvement for older pedestrians, cyclists and motorists, when compared to the former situation. However, for these elderly road users, the predictability of behaviour of other road users and/or the self-evidence of the code of behaviour they should practise themselves in certain traffic situations is crucial. Elderly road users appear to have problems under certain circumstances regarding their perception of the road course and steering activities. The 'drawing pin', the traffic hump with deflected cycle passage, the axis deviation, and the intersection plateau should be critically reevaluated. In contrast, the roundabout seems to be positively rated. The general conclusion is that with the current strategy for a 'sustainably safe' infrastructure, no 'separate' measures for elderly road users need to be applied, although certain application forms may require some adaptation to better suit elderly road user.


In the past few years different methods has been introduced regarding image inpainting i.e. Diffusion and exemplar-based inpainting. Different algorithms are present today but more efficient algorithms are required. In this paper, using K-NN based exemplar method and Super-Resolution method inpainting is explained.


have been produced at Korbach in northern Hesse since 1907, initially by the Frankfurt-based "Mitteldeutsche Gummiwarenfabrik Louis Peter AG", which merged with Hanover-based Continental AG in 1929. It goes without saying that the production techniques, the product range and the associated product characteristics and functional requirements have changed significantly since then. Today, the Continental Group produces tires using high-tech production machines, and the productivity of each individual plant is a crucial factor for the Group as a whole. In 2003, for example, on average the Korbach tire plant produced every day 28,000 car tires, 5,300 motorbike tires, 2,400 industrial tires and around 130 km of flexible hoses.


A simple phase-matching approach is employed as a design aid to engineer surface plasmon polariton states at the interface of an indium tin oxide layer on the top of a Bragg reflector. By altering the details of the reflector, and in particular the ordering of the layers and the thickness of the layer adjacent to the indium tin oxide, it is possible to readily adjust the energy of these states. Examples of structures engineered to give rise to distinctive features in the reflectivity spectra above the bulk screened plasma frequency for states of both possible polarizations are presented.


Measurements of the real (e′) and imaginary (e″) parts of the dielectric constant have been made on polyvinyl stearate at temperatures from −50° to +80°C and over a frequency range from 100 to 50 000 cps. Although no full relaxation dispersion region has been found in this frequency range, there are indications of the beginnings of a high‐frequency dispersion region just above the freezing point (49.1°C) in the liquid polymer. This dispersion cuts off or is ``frozen in'' rapidly as the sample freezes, giving evidence of a slight rotational freedom in the solid polymer near the freezing and melting points. Because of this ``freezing in'' of the dispersion mechanism it is supposed that the dipolar side chain is unable to rotate in the solid form because of the combined effects of the side‐chain crystalline field and angle which the C–O bond (between the main chain and side chain of the polymer) makes with the side‐chain axis. Specific volume measurements were made to supplement the above work. The measureme...


As data coming out from Japan on the level of contamination of food by radio-active fall-out from the nuclear weapon tests often differs remark ably from that obtained in other countries, an investigation was made to find the radio-ecological reason for it. We found less contribution of milk to total diet than European and American countries in Japan where various kinds of food of plant origin are contributing significantly and the level in the total diet only can be taken as standard because that in milk or in other food can not be a proportional to it. As more seasonal products are taken than continuous products in Japan, the mean storage time in diet is roughly measured as half a year. From the relation between the fall-out level on ground and in the diet, a rough measure to know about Sr-90 and Cs-137 level in the total diet was made using the accumulated ground deposit and the fall-rate in Tokyo. These differences between Japan and others are thought to be caused by the difference of usage of land surface for food production.


In order to improve the measurement precision for visual measuring system, coordinate measuring mathematical models of two typical vision sensor systems of a line-structured light visual sensor and a symmetrical binocular visual sensor are investigated with the trigonometric method. The relationship characteristics between measuring errors and structure parameters of the line structured light vision sensor and symmetric binocular stereo vision sensor are detailed analyzed based on error analysis theory in this paper. Through analyzing the relations between the coordinate measuring models and the structural parameters of visual sensor systems, the effect of the visual sensor structural parameters on the sensor measurement accuracy is probed. The error analysis explicitly illustrates the dependence of the visual sensor accuracy on the sensor structural parameters. Lastly, On the basis of the comprehensive consideration for designing an ideal visual sensor, the optimum rules of structural parameters are proposed, and the general design principles and methods of the two typical sensors are derived.


In a ballistic velocity measuring device, two photodetectors are spaced apart by an accurately known distance along a projectile path exposed to ambient light from the sky. The invention comprises a sunshield and light diffuser structure for each (or both) of the photodetectors to eliminate light reflection from the projectile which can cancel the "shadow" of the projectile and prevent the photodetector from responding to passage of the projectile; and to increase the level of light to the photodetectors by diffusing direct sunlight.


Author Contributions: Drs Hubiche and Valério had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Hubiche, Valério, del Giudice. Acquisition, analysis, or interpretation of data: All authors. Drafting of the manuscript: Hubiche, Valério, del Giudice. Critical revision of the manuscript for important intellectual content: All authors. Statistical analysis: Hubiche, Valério. Administrative, technical, or material support: Hubiche, Mahe, Phan. Study supervision: Hubiche, Boralevi, Bodemer Skandalis, del Giudice.


The sensitivity to radiation of mixtures of poly(methyl methacrylate) (PMMA) and polystyrene-co-acrylonitrile (SAN) was studied over the entire range of composition. Polystyrene-co-acrylonitrile, like polystyrene, is highly resistant to ionizing radiation, having a small G/sub x/ value for crosslinking (0.077) and an even smaller G/sub s/ value for main chain scission (0.055). In contrast, PMMA degrades readily under irradiation (with G/sub s/ = 1.2). In ..gamma..-irradiated blends, the behavior of each polymer is largely influenced by the presence of the other component. Gel formation in SAN is impeded by PMMA, as a result of a decrease in G/sub x/, and a concomitant increase in the ratio G/sub s//G/sub x/. Flexural strength measurements, along with molecular weight determinations by gel permeation chromatography, demonstrated that SAN had a market protective effect on PMMA by decreasing G/sub s/ (chain scission). This protective effect was not observed in earlier experiments with PMMA-PS blends, in spite of its chemical similarity to the system PMMA-SAN. The difference in behavior between PMMA-PS and PMMA-SAN may be explained on the basis of polymer compatibility. PMMA and SAN form a compatible pair, whereas PMMA and PS are incompatible; thus the short range protective effect of the phenyl groups in PSmore » is inhibited.« less


Single nucleotide polymorphisms (SNPs) in the promoter region of CD209 (cluster of differentiation 209) may influence expression levels, and higher expression of CD209 on immune cells correlate with severity of cartilage destruction in patients with rheumatoid arthritis (RA). Due to the lack of a comprehensive study, this study aimed to investigate the CD209 promoter variants and haplotypes in a Taiwanese population and the association with RA development. Deoxyribonucleic acid (DNA) of peripheral blood mononuclear cells from 126 RA patients and 124 healthy controls was purified, and the CD209 gene promoter was amplified by polymerase chain reaction and analyzed by Sanger sequencing. Results showed that a novel variant −96C>A polymorphism in CD209 promoter was identified in the Taiwanese population, and the frequency was significantly higher in RA patients than in controls (11.51% vs. 2.42%, P < .0001). The odds ratio (OR) for the development of RA was 5.88 (95% CI 2.35–14.74, P < .0001). Other known variants were also evaluated; for instance, −1180 T/T (rs7359874) was increased in RA patients, and the OR for the development of RA was 3.26, 95% CI 0.85–12.52, P = .07). Besides, the haplotype frequencies were calculated; −1180A‐939C‐871 T‐336 T‐139 T‐96A and −1180 T‐939 T‐871C‐336 T‐139C‐96A were increased in RA patients (P = .004 and 0.05, respectively). In summary, CD209‐96A variant could be an important factor for the development of RA in the Taiwanese population.


Infrared thermography was used to study the evolution and dynamics of hot zones on the top of a shallow packed-bed reactor (10 cm in diameter), packed with spherical catalyst pellets (Pd/Al2O3). The test reaction, the atmospheric oxidation of carbon monoxide, was run under conditions for which steady-state multiplicity exists. Slow cooling of the vessel housing the reactor close to its extinction temperature shifted the reactor from a fully ignited state to one with a hot region, separated by a sharp temperature front from the adjacent colder region (ΔT = 75 °C for a feed of 6 vol % CO). The hot zone exhibited one of three qualitatively different motions:  a breathing motion, an antiphase (standing wave) motion, or a hopping motion. In breathing motion, a the sharp temperature front moved back-and-forth. The breathing frequency increased upon cooling of the reactor. In antiphase motion, the hot zone moved rapidly and periodically from one side of the reactor to the other. In hopping motion, the hot zone r...


Given an arbitrary category \(\mathcal{C}\), a category \(pro^{*^f}\)-\(\mathcal{C}\) is constructed such that the known \(pro\)-\(\mathcal{C}\) category may be considered as a subcategory of \(pro^{*^f}\)-\(\mathcal{C}\) and that \(pro^{*^f}\)-\(\mathcal{C}\) may be considered as a subcategory of \(pro^*\)-\(\mathcal{C}\). Analogously to the construction of the shape category \(Sh_{(\mathcal{C},\mathcal{D})}\) and the coarse category \(Sh^*_{(\mathcal{C},\mathcal{D})}\), an (abstract) finite coarse shape category \(Sh^{*^f}_{(\mathcal{C},\mathcal{D})}\) is obtained. Between these three categories appropriate faithful functors are defined. The finite coarse shape is also defined by an intrinsic approach using the notion of the \(\epsilon\)-continuity. The isomorphism of the finite coarse shape categories obtained by these two approaches is constructed. Besides, an overview of some basic properties related to the notion of the \(\epsilon\)-continuity is given.


Seedlings of two durum wheat (Triticum durum L.) genotypes, sensitive and tolerant to cadmium, were treated at 3 to 4 leaves stage. The enzymic activities of catalase glutathione s-transferase (GST) and guaiacol peroxidase (GPX) in the case of sensitive genotype significantly increased compared to the control. The activity level of catalase (CAT) and ascorbate peroxidase (APX), however, did not show a significant change. Moreover, the enzymic activity of GPX, GST, CAT and also APX, in the case of cadmium utilization had not a significant change compared to the control. It is argued that the sum of activities of hydrogen peroxide (H2O2)-scavenging enzymes helped control of the amount of the pernicious compound (H2O2) at tolerant genotype. Cadmium stress led to the significant increase of malondialdehyde (MDA) in both durum wheat genotypes, although membrane damage and lipid peroxidation were more severe with regard to sensitive genotype. It follows that the augmentation of H2O2 and the drop in GST activity substantiate further increase in the amount of MDA in sensitive genotype. It is concluded that the activity of H2O2 scavenging enzymes and that of GST enzyme have a crucial role in detoxifying toxic compounds leading to more resistance against salt stress.


To the Editor:— I would like to comment on the article, "Cholecystography with Bunamiodyl," by Meszaros and Rich inThe Journal, April 23, page 1884. I have been using bunamiodyl (Orabilex) in this hospital for the last six months. The prescribed dosage has been adhered to, and the examinations are often combined with those of the upper gastrointestinal tract. In 111 examinations made with bunamiodye only one patient has had diarrhea, one has had dysuria, and five patients have had a moderate urticaria over the extremities and neck. Bunamiodyl was used as a medium for gallbladder examinations of executives of a large company, and after 43 examinations I had to discontinue its use. There were five reactions: two patients had a severe esophageal spasm; one patient had a severe urticaria over the extremities and entire trunk; and two patients had a moderately severe urticaria over the extremities. These five patients


Background Complex Regional Pain Syndrome (CRPS) is a clinical syndrome composed of chronic pain, motor impairment, and autonomic dysfunction, usually affecting a limb. Although CRPS seems to be a peripheral disorder, it is accompanied by parietal alterations leading to body schema impairments (the online representations of the body). Impairments to body structural description (the topographical bodily map) were not assessed systematically in CRPS. A patient we encountered with severe disruption to her bodily structural description led us to study this domain further. Aims To document aberrant body structural description in subjects with CRPS using an object assembly task. Methods Body Schema Study: 6 subjects with CRPS-I and six age and sex-matched healthy controls completed visual puzzles taken from WAIS-III and WAIS-R. The puzzles were either related to the human body or non-human body objects. Mann–Whitney U-tests were performed to compare groups' performances. Results The CRPS group received relatively lower scores compared to controls for human body objects (u = 3, p < 0.05), whereas the non-human object scoring did not reveal significant differences between groups (u = 9, p > 0.05). Conclusion CRPS subjects suffer from impaired body structural description, taking the form of body parts disassembly and body parts discontinuity. This impairment can serve as a nidus for aberrant psychological representation of the body.


Energy is the most valuable resource in wireless sensor networks; this resource is limited and much in demand during routing and communication between sensor nodes. Hierarchy structuring of the network into clusters allows reducing the energy consumption by using small distance transmissions within clusters in a multihop manner. In this article, we choose to use a hybrid routing protocol named Efficient Honeycomb Clustering Algorithm (EHCA), which is at the same time hierarchical and geographical protocol by using honeycomb clustering. This kind of clustering guarantees the balancing of the energy consumption through changing in each round the location of the cluster head, which is in a given vertex of the honeycomb cluster. The combination of geographical and hierarchical routing with the use of honeycomb clustering has proved its efficiency; the performances of our protocol outperform the existing protocols in terms of the number of nodes alive, the latency of data delivery, and the percentage of successful data delivery to the sinks. The simulations testify the superiority of our protocol against the existing geographical and hierarchical protocols.


Herein, ultradispersed In2S3 nanoparticle (NP)/TiO2 nanobelt (NB) heterostructures with an intimate interfacial coupling effect are synthesized from the consideration of combining the visible/near‐infrared photoabsorption property of In2S3 with the excellent UV photocatalytic property of TiO2. In this process, the 1D TiO2 NBs not only perform as the support to form the heterostructure, but are also employed as a dispersant to confine the aggregation of In2S3 NPs. As expected, the obtained In2S3 NP/TiO2 NB heterostructure gives rise to a prominently strong optical absorption in the full solar region of 300–1800 nm, and thus displays a desired photocatalytic degradation of tetracycline in full utilization of all solar energy, compared with that of pristine In2S3 and TiO2. Besides, the In2S3 NP/TiO2 NB heterostructure photocatalysts have no selectivity and can effectively degrade other different kinds of organic pollutants, including cationic dyes (methyl blue and rhodamine B) and colorless chemical pollutants (phenol and salicylic acid). The exceptional photocatalytic enhancement is due to the synergistic interactions of heterojunction with the strong interfacial coupling effect, the In2S3 extended light absorption, efficient photogenerated e−/h+ pair separation, and fully exposed reactive sites induced by uniform packing of the ultrasmall In2S3.


The present research work was developed in the Fundo Muchick Company -
DANPER SAC, which, like any company, seeks to be a leader in its field, and to
achieve this, it has been investigated whether the current compensations perceived
have a positive impact on the performance of the collaborators, since compensation
is considered one of the main factors that influence the motivation of employees,
and for the company is a strategic method that can be used to retain the best talent
of the company. The non-experimental, cross-sectional and correlational and descriptive type of research, the Inductive-Deductive Method, the Hypothetical-Deductive Method was
used, the survey was also used as a research technique, the Cronbach's Alpha
method was used to verify the reliability of the data obtained and the Pearson
coefficient was used to establish the relationship of the compensations with the labor
performance. For the development of the research work, the population that was made up of the collaborators of Empresa Fundo Muchick - DANPER SAC, a representative sample was obtained, using the statistical method, then the data collection instrument was applied, with the information obtained it was possible to meet the objectives of the
thesis, check the research hypothesis, and determine that the compensations are
related to the work performance in a positive and significant way, where r = 0.82.


To study the relationship between partions and compositions of positive integers is a new topic proposed in recent years.In this paper,some lackings and errors in corresponding literatures are indicated and corrected,some results in the literactures are generalized,new identities for partitions and compositions of positive integers are given.


Bioabsorbable plates and screws (BPS) are now widely used as a well-established internal fixation method for various osteosynthetic surgeries, such as fixation of fractures or osteotomies. One of the BPS's main advantages is that surgical removal is unnecessary since they are ostensibly fully


Consumption of general purpose broad-spectrum antibiotics is associated with rising levels of antimicrobial resistance. Additionally, industry reports suggest that lack of profitability associated with narrowly targeted pathogens is a potential reason why firms are not undertaking new antibiotic related R&D. In this paper we use aggregate sales data on antibiotics from the UK to estimate a structural demand model and evaluate market performance of firms by spectral activity. We find that broad-spectrum antibiotics are more profitable than narrow-spectrum drugs, though the profitability has increased over time for both types due to a decline in costs, the costs of narrow stay higher. We simulate counterfactual scenarios to evaluate the effectiveness of cost-side interventions to shift demand from broad- to narrow-spectrum drugs. Using the last full year of data, simulations show that if unit costs of broad-spectrum were as high as those of narrow-spectrum antibiotics (say due to a unit tax), demand for broad-spectrum would fall by 28.1%, while that of narrow-spectrum would increase by 43.8%. The total cost of such an intervention would be $962 per thousand individuals or a total of $61.26 million, and is inclusive of change in consumer welfare and additional cost of testing for pathogens. Impact of other more selective taxes on subsets of broad-spectrum drugs is also analyzed.


A strong limit theorem is proved by constructing two nonnegative martingales. Then it is applied to the study of the even-odd Markov chain fields indexed by a extended Bethe tree. Finally, a strong limit theorem for tree model is gained.


Creatively taking the long history of development in our ancient country as background,this article analyzes the model of action of Sci-Tech to economy,and finds that Sci-Tech promotes economy apprentely.However there is a ceiling effect in this promotion.Then it analyzes the models of how different science technological factors influencing economy,which include numbers of scientific discoveries,agronomy,other subjects,and different types and specific gravity of scientists.Based on those above analysis,the article puts forward the enlightenment of that ceiling effect,and provides a metered reference for the policy of our modern Sci-Tech and the economic development.


The discussion of the life stories of stars presented so far has suffered from a bias—what we might call "single-star chauvinism." Because the human race developed around a star that goes through life alone, we tend to think of most stars in isolation. But as we saw in The Stars: A Celestial Census, it now appears that as many as half of all stars may develop in binary systems—those in which two stars are born in each other's gravitational embrace and go through life orbiting a common center of mass.


The characteristics of runaway electron beams downstream of a foil anode were studied at high pressures of helium, hydrogen, neon, and nitrogen. High-voltage pulses were applied to the tubular cathode - plane anode gap. The SLEP-150 generator, with no transmission line, produced voltage pulses of amplitude ∼160 kV across a high-resistance load; the incident wave amplitude in the transmission line was ∼50 kV The pulse rise time was ∼250 ps at a level of 0.1-0.9 and the FWHM of the voltage pulse with a matched load was ∼1 ns. The use of the transmission line in the SLEP-150 generator allowed recording the incident and reflected voltage waves and to recover the voltage across the gap during the generation of the electron beam. The RADAN-220 generator produced voltage pulses of amplitude 250 kV, FWHM with a matched load 2 ns, and rise time 0.5 ns. It is shown that the highest amplitudes of a supershort avalanche electron beam (SAEB [1]) of pulse duration about 100 ps are attained in helium, hydrogen, and nitrogen at a pressure of ∼60, ∼30, and ∼10 torr, respectively. Decreasing the pressure 1.5-2 times of helium (p < 60 torr), hydrogen (p < 30 torr) and nitrogen (p < 10 torr) changes the mode of the e-beam generation. It is demonstrated that decreasing the pressure increases the beam current amplitude and the voltage pulse duration across the gap. It is found that increasing the pressure of helium, hydrogen, and nitrogen to hundreds of torr decreases the delay time between the instants the voltage pulse is applied to the gap and the SAEB is generated as well as the maximum voltage across the gap. Using the extracted data, estimates show that with the generators used, optimization of all parameters of the gas diode makes possible a SAEB current amplitude of about 500 A at a helium pressure of 60 torr. As the mode of the beam generation is changed due to the decrease in pressure from the above values, one can gradually control the FWHM of the beam current pulse between 100 and 500 ps in all gases studied. In this case, the maximum amplitude of the beam current is about 1 kA and is greater than the maximum SAEB amplitudes. At low pressures of helium, hydrogen and nitrogen in the gas diode, the amplitude of the beam current decreases and its duration continues to increase to over the duration of the generator pulse with the matched load.


Human resource development and continuous training are a precondition for organizational and socio-economic resilience and development. It is also vital to build integrated training programs, especially for the unemployed nowadays, considering the major challenges caused by the COVID-19 pandemic crisis in various labor markets internationally. This article aims to distinguish fundamental theoretical and practical dimensions of structuring business training programs and supporting learning and innovation after investigating critical trends of conceptual readjustment of modern management theory. A significant conclusion is that a business training program has to synthesize the organization's strategic, technological, and managerial potential and goals (Stra.Tech.Man approach), valorizing the basic principles of integrated planning, organizing, implementing, and controlling. A novel training program framework is suggested, attributing particular weight to developing structured mechanisms for training unemployed population groups at the local level.


This study presents a design for an absorber used in a solar air collector for an indirect solar dryer. The absorber comprises two aluminium plates corrugated and joined together to form parallel cylinders, enabling airflow within the collector. This research aims to experimentally examine the drying process of two types of bananas, one from Morocco and the other from abroad, using the designed solar air collector. Additionally, the study aims to investigate the peculiarities of the drying process and the performance of the solar dryer employed. The experiments were conducted by subjecting the bananas to the designed solar air collector, and the evolution of drying was monitored. The initial mass of the bananas used was 631.6 g for the Moroccan banana and 713.6 g for the Export banana. After the drying process, the mass of the Moroccan banana reduced to 77.5 g, while the Export banana reduced to 137.3 g, indicating significant moisture removal. The percentage of the amount of water extracted (Q) from the bananas was found to be 87.7% for the Moroccan banana and 80.8% for the Export banana. These results demonstrate the effectiveness of the corrugated aluminium plate absorber in facilitating the drying process in the solar air collector. The significant reduction in the mass of the bananas and the high percentage of water extraction highlight the efficiency of the solar dryer in removing moisture from the agricultural produce. The findings of this study contribute to the understanding of the drying process of bananas and offer valuable insights for the design and optimization of solar drying systems for agricultural applications.


This zip file/CD-ROM contains the PDF of a presentation that describes Texas Department of Transportation (TxDOT) Research Project 0-6444 "Treatments for Clays in Aggregates Used to Produce Cement Concrete, Bituminous Materials, and Chip Seals" and describes the test methods performed and findings. It also includes an Excel spreadsheet "Dosage-calculation-surfactant.xlsx"


: Political art conceived relativistically presupposes something "absolute", the appropriate ("to metrion") and "all that which has its seat in the middle between two extremes" (284e). But this refutation of political relativism is only a propaedeutical step for the exposition of the "exact itself" ("auto t'akribes") (284d2), that is, the good.


WITH A NUMBER OF TEST TYRES OF SIZE 165 SR 13 WHICH ARE A REPRESENTATIVE SELECTION WITH RESPECT TO GRIPPING ABILITY, MEASUREMENTS WERE CARRIED OUT FOR TYRE NOISE ON DRY ROAD SURFACES USING THE FKFS SINGLE WHEEL TRAILER AND, ON WET SURFACES, THE SLIDING COEFFICIENT WAS MEASURED USING THE STUTTGART FRICTION MEASURING DEVICE. THE INVESTIGATIONS SHOW THAT THE STRIVING FOR LOW TYRE NOISE DOES NOT COUNTERACT THE DESIRE FOR HIGH SKIDDING SAFETY. FURTHER THE PROBLEM OF TYRE NOISE GENERATION IS INVESTIGATED BY BASIC EXPERIMENTS ON TEST RIGS AND ROAD SURFACES. IT IS SHOWN THAT THE GENERAL VIEW OF THE GENERATION OF TYRE NOISES BY A SEQUENCE OF AIR DISPLACEMENTS FROM CAVITIES IN TYRE TREAD (AIR PUMPING) IS NOT CORRECT. FURTHER IT IS SEEN FROM THE RESEARCH THAT BOUNCING OF THE TREAD LEADS TO VIBRATION IN THE TYRE, WHICH TOGETHER WITH SLIDING ON THE TREAD IS THE CAUSE OF TYRE NOISE. ON EXTREMELY UNEVEN SURFACES, FOR EXAMPLE COBBLED SECTIONS OF ROAD, TYRE VIBRATIONS ARE PREDOMINANTLY THE CAUSE OF TYRE NOISE.


Let $b\geq 2$ be an integer and $\hat{v}$ a real number. Among other results, we compute the Hausdorff dimension of the set of real numbers ${\it\xi}$ with the property that, for every sufficiently large integer $N$, there exists an integer $n$ such that $1\leq n\leq N$ and the distance between $b^{n}{\it\xi}$ and its nearest integer is at most equal to $b^{-\hat{v}N}$. We further solve the same question when replacing $b^{n}{\it\xi}$ by $T_{{\it\beta}}^{n}{\it\xi}$, where $T_{{\it\beta}}$ denotes the classical ${\it\beta}$-transformation.


Received 2 August 2020; editorial decision 6 November 2020; accepted 10 November 2020; published online November 17, 2020. Correspondence: Rachel L. Winer, PhD, Department of Epidemiology, University of Washington, Box 351619, 3980 15th Ave NE, Seattle, WA 98195 (firstname.lastname@example.com). The Journal of Infectious Diseases 2021;224:123–32 © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: email@example.com. DOI: 10.1093/infdis/jiaa711 Understanding the Role of Emerging Vitamin D Biomarkers on Short-term Persistence of High-Risk Human Papillomavirus Infection Among Mid-Adult Women


Background
The reduction of weight in working women with obesity (WWO) is an important challenge for health policy. Although dietary interventions and various forms of exercise are widely available, patient adherence is usually low. A promising alternative is Suryanamaskara (SN). SN was promoted for weight reduction in WWO, but there was little evidence of its efficacy.
Objective
To assess the efficacy of SN in WWO
Methods
Sixty WWO were randomized into 2 groups: SN (48.5±7.9 years) and control (46.4±8.9 years). The body mass index (BMI) was assessed at weeks 0 and 3 of all the subjects. Within-group analyses were performed using SPSS version 21.
Results
The statistical analysis showed a 3.08% decrease (p<0.001) in the post-SN group as compared to the pre-SN group and a 1.11% increase (p<0.001) in the post-control group as compared to the pre-control group.
Conclusion
The findings of this study demonstrate that SN is associated with weight reduction in WWO.


Wheat is one of the major cereal crops with annual global production over 600 MT from about 200 M hectares (FAO 2012). The cultivation of wheat started about 10,000 years ago as part of the Neolithic revolution which state a transition from hunting and gathering of food to settle agriculture. Earlier cultivated forms of wheat were diploid (einkorn) and tetraploid (emmer) with known initial origin of the south-eastern part of Turkey (Dubcovsky and Dvorak, 2007). Subsequent evolutionary adaptation and continuous research produced hexaploid bread wheat that is currently widely adapted in about 95% area of world wheat. Globally, all crop production practices are being highly challeged by biotic and abiotic stresses. Biotic stresses especially insect pests and dieseases causes devastating damage in terms of yield and quality. On average pests cause 20-37% yield losses woldwide which translating to approximately $70 billion annually (Pimentel et al., 1997). In agro-ecosystems, herbivore insects are abudant and likely to colonise within same population and disperse from one crop field to another de‐ pending on the availablility of plant tissues and feeding behaviour of insects. Quantitative feeding style of the herbivore insect on specific crop resulting significant damage to the crop during the entire life cyle which is believed specific insect as pest of that perticular crop. Single pest may attack multiple crops within single growing season that make crop rotation and pest management more challenged. Wheat producing areas encounter with either sucking and pericing pests or plant tissue feeding pests. Regional pests also observed in wheat growing areas as major damaging pests woldwide. The breeding strategy againsts these insects/pests heavily rely on the inheritance of resistance mechanism in the crops under consideration. The insect resitance is mainly goverened by three types of mechanisms/genes i.e., oligogenes; where resistance is confered by single genes as in case of hessian fly in wheat, polygenes; where


T h c Angel of Death proved a ubiquitous intruder in our lives during the winter and spring of 1995, abusing family and friends alike in ways both symbolically prescient and painfully real. Before the new year had even begun, my father placed my decreasingly mobile, 89-year-old grandmother in a nursing home, severing her ties to the only relational ecosystem she had known for over half a century. My spouse Bob and I had but begun to realize the dying process implicit in "our" granny's forced relocation, when the young lover of an older gay friend and mentor died of an insidious cancer which had invaded his already AIDS-ravaged immune system. Fresh from that memorial service, we paid our first visit to granny in hcr ncw rcsidcnce and were deeply saddened by the obvious diminishment in her embodied quality of life, a diminishment hastened at least in part by my father's earlier abuse by neglect and ineptitude. While we were visiting granny, the oldest of our three dogs died unexpectedly, following some minor skin surgery; her involuntary nervous system no doubt still impaired by residues of the anesthetic, her stomach literally turned, quickly killing her in the space of some twenty minutes. Within only a couple of weeks of burying our beloved if cantankerous Abigail beneath a blanket of snow she would have loved to romp in, we learned that Bob's best friend and the designated executor for his will, a friend whom Bob had just visited the day before, had died suddenly in the wee hours, succumbing to his very first round of AIDS-related pneumocystis carinii pneumonia. A return visit to granny demonstrated to us just how much an individual can decline in a Mere six weeks, losing virtually all remaining independent mobility and becoming dependcnt not just upon a walker, but upon wheel chairs and nursing assistance for the simplest and most personal of tasks. At this point my father put granny's longtime home on the market and Bob and I became accomplices in its dismantling. Gradually dispossessing our granny meant the slow death of the only constant family home I've known


HK-40 has been the predominant alloy for reformer or cracking tubes in petrochemical plants. The material degradation of HK-40 tubes in using high temperature is due to microstructural changes, especially about carbide behavior and crack formation. The structure of HK-40 is characterized by a skeletal eutectic carbide network and a huge amount of secondary carbides in an austenitic matrix. Carbides on grain boundary form continuous plate-like shape in the as-cast condition, and coalesce progressively to increase discontinuity of itself during creep. Cavities initiate at this grain boundary and cracking is caused by grain boundary sliding of carbides denuded area. The secondary carbides in matrix explicitly affect crack growth behavior and stress-rupture elongation. But the carbides precipitated in grain boundary at the first stage of heat treatment improve rupture time and strain by the grain boundary strengthening.


Abstract This article deals with the feasibility of the use of wheat protein glue to produce general purpose particleboards from bagasse, canola, and hemp chips and of decreasing the formaldehyde emission by using a bioproduct adhesive. Three series of panels were produced using wood chips in the surface layers and a mixture of annual plants with industrial wood in the middle layers. Particleboards were manufactured using various annual plants. Wheat protein was used in combination with urea-formaldehyde (UF) resin in the surface layers. Pure UF was only used in the middle layer. Panels were tested for some physical and mechanical properties. In addition, the formaldehyde emission according to the perforator method and the bottle method was determined. The data were compared with the respective properties specified by the Deutsches Institut fur Normung EN 312-2 standard for commercial wood-based particleboard. The results showed that all mechanical properties greatly exceeded the standard requirements for...


A YEAR or so ago the newspapers mentioned the discovery of a ruined city in western Mexico by Mr. William Nivens. Since then collections have been brought to New York City, and ample means thus furnished to judge of its characteristics. In the Bulletin of the American Geographical Society for July of this year, Mr. Nivens has a short article on the subject. The ruins are very extensive and indicate a skill in stone work above that of many tribes, but decidedly inferior to that of the best Aztec civilzation. His article speaks of a tablet with hieroglyphic characters, but examples of such are extremely rare, and perhaps of doubtful origin. The stones are, as a rule, not dressed with skill and the structures were not lofty. From all this we may conclude that we have in these extensive remains the relics of an inferior, subordinate culture-center of Aztec civilization; but tlhis, of course, does not in any way diminish the interest which attaches to Mr. Nivens' explorations.


Data mining is a search for relationship and patterns that exist in large database. Clustering is an important data mining technique. Because of the complexity and the high dimensionality of gene expression data, classification of a disease samples remains a challenge. Hierarchical clustering and partitioning clustering is used to identify patterns of gene expression useful for classification of samples. In this paper, we make a comparative study of three partitioning methods namely k-means, PAM and rough k-means to classify the cancer dataset.


This paper introduces mixture ratio design of cement concrete of the Xinqing Large Bridge,and how to appraise and analyze all kingpost's intensity by mathematical statistics method.