There is good reason to believe that Paul Tillich would have objected to the title of this paper. Several years ago I heard him begin a lecture on 'Religious Existentialism' with the comment, 'There is no such thing as Religious Existentialism because there is only Religious Existentialism'. Similarly, he might have objected to the present paper's title by suggesting that every search for knowledge is, consciously or unconsciously, a religious search.


During the "Age of Discovery", Europeans came into contact with a variety of different cultures from all over the globe. In Asia, they stumbled upon China and Japan, two welldeveloped countries, which were considered as civilized as those of Europe (Rietbergen, 2002, p. 64). The Dutch were the only European allowed into Japan, where from 1641 onwards, they were confined on the little artificial island of Deshima in the bay of Nagasaki (Rietbergen, 2003, p. 176). Here a company of approximately 20 men lived for a year or longer, under strict supervision of the guards, often without any proficiency in the Japanese language, with professional translators controlling all contacts of these foreigners with Japan (ibid, p. 181). Consequently, these Europeans had a monopoly on the representation of Japan. One of the most notable works on Japan of this era was The History of Japan by Engelbert Kaempfer. Although the work contains 'Othering', neither of Thompson's definitions would be encompassing. In line with the European realisation that these cultures were equally civilized, I argue that Kaempfer's work notes the differences between Japan and Europe to highlight the faults of Europe. Constrained by both time and space, this chapter mainly discusses Kaempfer's writing on the regulation of Japan, more specifically, the regulation as it was imposed by the shoguns of the Tokugawa dynasty. That subject is chosen because Japan's isolation and generally harsh laws, which were the result of Tokugawa rule, were of particular interest to his European readership (Michel, 2000, p. 111). Regulation here refers to the manner in which the Japanese government sought to exert control; it encompasses law-making, regulation of foreigners and the actions of the Japanese people under regulation. Thus, this chapter addresses the way in which Kaempfer used Tokugawa regulation as a lens for describing the Other, and how this Other was used to express Kaempfer's personal beliefs.


We review the results of a large project for development a Maintenance Advisory System of a refinery with more than 2000 rotating machines. The system contains 18 on-line monitoring vibration diagnostic systems with a unique central database for 100 strategically most important machines and one offline diagnostic system with an independent knowledgeand database. The machines malfunction and fault detection is based on different diagnostic technologies like 3D Vibration Analysis, Thermography, Leakage Detection, Used Oil Analysis and Ferrography. The vibration analysis system is automatic expert software. Different interactive expert systems were developed for the rest analysis techniques. The results of fault detection and malfunction analysis integrated and displayed in one software system called BDES (Board of Diagnostic Expert System), which is a complex condition monitoring system for rotating machinery. We describe shortly the ExpertALERT artificial intelligence system, as well as ThermoALERT, LeakageALERT, OilALERT, and FerroALERT interactive expert analysis software, their applications and connection to SAP PM Maintenance module of the Refinery. Operative maintenance decisions and maintenance planning is grounded on integrated fault diagnostics and severity estimation. The IFSS is a webbased Information and Fault Statistic System, which helps strategic decision making of the maintenance management using statistical analysis of identified faults in territory allocation and trending in time. The Condition Based Maintenance strategy carried out. We describe the hardware and software solutions and show practical examples. Introduction This paper shortly describes the results of software development, what was realized in the framework of MOL's (Hungarian Oil and Gas Company) On-line Diagnostic Project. The main goal of the project was the installation of on-line vibration monitoring systems for surveillance 100 strategically most important rotating machinery. The new on-line systems were integrated into one surveillance system, which means that, all of them work into one central database, placed on a central server computer in the server room of the Refinery Szazhalombatta. Parallel to the on-line systems have been installed an off-line vibration monitoring system with two ExpertALERT automated asset management diagnostic software with two independent database. These databases are synchronized by replication. The off-line and on-line databases of ExpertALERT contain the measured data, the results of data evaluation, the analysis results and the reports on the machines condition with machine faults, an estimation of fault severity, and recommendation for maintenance action. Goal of software development As the part of the "On-line Asset Management Project" the next software development goals were formulate: • Develop specific expert systems for analysis the next diagnostic data: thermo images of rotating machines, oil analysis, Ferrography and sealing leak detection, • Integrate the results of ExpertALERT and the newly developed expert software into a unique asset management system, • Develop a software, handling the risk matrix for rotating machinery risk classification, • Develop a web-based information system for spreading the diagnostic information in the company's LAN, • Develop an interface between the diagnostic systems and the SAP PM module, www.dellta3n.hu 1 • Develop a software module for scheduling of measurements, • Develop a machine registry database developing software, Figure 1. shows the schema of the developed software system. Figure 1. Schema of the software system developed for MOL Refinery This schema does not contain the Machine Registry software, which is standalone software. The software module for scheduling measurement work is integrated into the SAP Interface. Characteristics of the software modules ExpertALERTTM software developed by AzimaDLI includes an imbedded rule based diagnostic system to help you screen through large amounts of data efficiently and focus on machines with problems. Although the diagnostic system is well proven and extremely accurate, a report editor is included should you wish to alter the reports or add comments. The ability to quickly analyze large amounts of data and accurately identify machines with problems is a key element for efficient vibration services. In a typical plant, about 10 20 % of all machines tested will have inherent mechanical faults. Within this group, far fewer will require immediate service. The distinguishing feature of AzimaDLI's rule-based, automated diagnostic system is that it identifies problem machines and focuses on manually reviewing the data from these machines. This approach is far more efficient than analyzing data from every single installed machine. Customers who use this automated approach typically receive a 20:1 benefit-to-cost ratio. The diagnostic system contains over 4,500 individual fault templates. These templates are based on empirical data acquired from hundreds of thousands of machine tests conducted over more than twenty years. They can be applied to more than forty general machine component types, including motors, pumps, fans, blowers, gearboxes, compressors, generators, turbines and machine tools. The system analyzes machine test data in a matter of seconds and produces a concise report that lists specific mechanical faults, the severity of each fault and an overall recommendation Compared with systems that simply indicate that a machine is in 'alarm' mode, this


are only three certified reformatories, viz.: (1) The Royal Victoria Homes, Brentry, near Bristol, which propose that the County Council should enter into an agreement (a) for not fewer than five cases and for not less than five years; (b) to pay ?10 per bed per year for capital outlay; (c) to pay 6d. per day for each case sent. (2) Lady Somerset's Home, which proposes that the Council should purchase a portion of the freehold and should erect all necessary buildings and pay 16s. a week


Regarding the rate-making method of engineering insurance, there isn't a uniform standard in the field of insurance for a long time. Although there is a trend to calculate the engineering insurance rate based on the method of risk coefficient adjustment recent years, it doesn't consider the significance of the risk synthetically by combining project cost and doesn't consider the risk control condition of the insurance policy holder adequately. In order to define the engineering insurance rate objectively, this paper will evaluate the risk with the AHP method and intensively consider the cognition and control on risk by contractors and project owners. This paper also proposes a method to determine the adjustment coefficient of engineering insurance rate based on AHP under the condition of unit price contract, and proves the feasibility of the method.


In this paper, the authors presented an integration strategy for metal gate GAA transistors made by SON process using poly-gate replacement through contact hole (PRETCH). Double gate (DG) type MOSFETs, including planar DG gate-all-around and fin-FETs are today known as the best candidates for the ultimate sealing of the logic CMOS technologies on silicon. One of the main difficulties in optimizing DG devices is the control of the threshold voltage (V/sub th/) from high performances to low power devices. With polysilicon gates, a higher channel doping has to be used when lowering the silicon thickness (T/sub Si/). This adjustment strategy has its limits and thus, gate workfunction engineering seems necessary for thin DG transistors.


In this paper, we propose a new graph-based method for change point detection. We first construct an alternative directed K-nearest neighbour graph and propose a new χ like statistics with hypothesis testing methods for change point detection, and then give a numerical approximation method to calculate the p-value. As an application, we conduct change point detection for the character-event matrix of Chinese novel called A Dream in Red Mansions.


The emerging sixth-generation networks have to provide effective support to a wide plethora of novel disruptive heterogeneous applications. This paper models the probabilistic end-to-end delay bound for the virtual reality services in the presence of heterogeneous traffic flows by resorting to the stochastic network calculus principles and exploiting the martingale envelopes. The paper presents the network performance analysis under the assumption of different scheduling policies, considering both the earliest deadline first and the first-in-first-out queue discipline. Furthermore, differently from previous literature, the probabilistic per-flow bounds have been formulated taking into account a number of traffic flows greater than two, which results in a theoretical analysis that is remarkably more complex than the case in which only two concurrent flows are considered. Finally, the validity of the theoretical bounds have been confirmed by the evident closeness between the analytical predictions and the actual simulation results considering, for the sake of argument, four concurrent traffic flows with heterogeneous quality-of-service constraints. That closeness exhibits the ability of the proposed analysis in fitting the actual behavior of the system, representing a suitable theoretical tool to support resource allocation strategies, without violating service constraints.


A simple electroanalytical method was developed to detect dopamine (DA) neurotransmitter by using carbon quantum dots (CQDs) modified electrode. To synthesis CQDs, a green electrochemical method was adopted and graphite rods were used as anode and cathodes in 0.1 M NaOH/ethanol (EtOH) as the electrolyte solution. As-synthesized CQD showed different particle sizes depending on the applied current with time as characterized by UV-visible spectroscopy. The particle size, lattice structure and functional groups of CQDs were analyzed by the HR-TEM, XRD and FT-IR, respectively. The CQD exhibited a green fluorescence under UV light (365 nm). Moreover, CQD dispersion was used to modify glassy carbon electrode (GCE) and screen-printed carbon electrode (SPCE) to study their electrochemical and electrocatalytic properties. The both GCE/CQD and SPCE/CQD showed higher electrocatalytic activity toward oxidation of dopamine (DA) in phosphate buffered saline (PBS) solution (pH = 7.4). In order to avoid interferences, Nafion (Nf) layer was coated on the CQD film modified electrode. The effect of scan rate on DA oxidation was studied from 10 to 150 mV/s. The calibration curve was recorded for DA from 1 to 7 μM using a SPCE/CQD and the limit of detection was found to be 0.099 μM. The observed electro-catalytic activity of the CQD was attributed to their negatively charged functional groups which attracted positively charged DA in 0.1 M PBS. In addition, detection of DA in spiked human urine sample was demonstrated with satisfactory recovery analysis. © The Author(s) 2018. Published by ECS. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License (CC BY, http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse of the work in any medium, provided the original work is properly cited. [DOI: 10.1149/2.0191812jes]


When taken up by leaves, SO{sub 2} can affect various sites like biomembranes or enzymes, and may cause intracellular acidification. It is known that plants are capable of detoxifying SO{sub 2} in different cell organelles by oxidation or reductive metabolization and thereby decrease of even avoid damage. Detoxification via oxidation also takes place in the aqueous phase of the cell wall. Fumigation of leaves with SO{sub 2} resulted in an increase in the amount of extractable soluble cell wall peroxidase. We have isolated soluble and cell wall bound peroxidases from barley leaves and spruce needles, both of which are capable of oxidizing sulfite to sulfate in vitro and in situ (ca. 2 {mu}mol SO{sub 3}{sup 2{minus}} oxidized mg{sup {minus}1} Chl and h). To what extent this process contributes to the overall detoxification of leaves to SO{sub 2} is not known at present.


Sleep disturbance from obstructive sleep apnea (OSA) impairs overnight memory processing. This may be mediated by changes to slow wave sleep (SWS) as less slow wave activity (SWA) is associated with worse overnight spatial and declarative memory. We developed a within-subjects model of SWS-specific CPAP-withdrawal to create 3 polysomnologically (PSG)-verified conditions of 1) stable-SWS on CPAP, 2) SWS-fragmentation with intermittent hypoxemia (OSAsws), and 3) SWS-fragmentation with reduced hypoxemia (OSAsws+O2). Using these conditions, we sought to dissociate of effects of SWS disruption and intermittent hypoxemia on overnight spatial navigational memory.

 We included 33 patients (7 female, average age 54yrs) with moderate-to-severe OSA (AHI4%>20/hr) who were CPAP-treatment adherent. During each PSG visit, they explored one of three 3D maze environments, performing 3 timed trials before and after each of 3 randomized and counterbalanced SWS disruption conditions [1)CPAP, 2)OSASWS & 3)OSASWS+O2]. %SWS, OSA severity during SWS, frontal SWA(0.5-4 Hz), and overnight change in maze completion times were compared according to PSG condition using Friedman Rank Sum and Conover's tests. The relationship between SWA and maze performance was tested using Pearson correlation coefficient.

 %SWS was significantly greater during CPAP compared to CPAP-withdrawal conditions (CPAP=17.2%, OSAsws=13.3%, OSAsws+O2=13.8%, p< 0.02). Apnea hypopnea index (AHI3A) in SWS during CPAP-withdrawal was significantly greater compared to CPAP (CPAP=0/hr, OSAsws=24.4/hr, OSAsws+O2=19.3/hr, p< 0.00001). Hypoxic burden in SWS was significantly reduced in the OSAsws+O2 condition vs OSAsws (23 %min/hr vs 37 %min/hr, p < 0.001). No significant differences were observed between the three conditions for SWA or overnight change in maze completion times. When including all PSG visits, greater SWA was significantly associated with better overnight maze improvements (R=0.28,p< 0.01) which approached significance for the CPAP condition in isolation (R=0.33,p=0.068).

 SWS-specific CPAP-withdrawal resulted in recurrence of mild OSA in SWS; supplemental oxygen reduced the hypoxic burden, but SWA did not differ between OSA with hypoxemia and without. There was, however, an overall positive relationship between SWA and maze performance. These observations suggest that the effect on spatial navigation of hypoxia in OSA is mediated by disruption of SWA.

 R01AG056682, AASM Focused Project Award.


AIMS
To investigate the regulating effects of catalpol on the hypothalamic-pituitary- adrenocortical-axis (HPA) in an Alzheimer's disease (AD) rat model.

METHODS
Healthy male Wistar Rats were selected. The AD model was generated by orthotopic injection of beta-amyloid 25-35 (Abeta25-35) into the right lateral ventricle. The animals were divided into five study groups: Catalpol at low dose (5 mg/kg), Catalpol at high dose (10 mg/kg), model control group and sham surgery control group, n = 9 respectively. The serum concentration of hydrocortisone (HYD), adrenocorticotropin (ACTH) and corticotropin releasing hormone (CRH) determined by Enzyme-Linked Immunosorbent Assay (ELISA). Structural alterations of the hypothalamus were examined by H&E stain and electron microscope. The CRH receptor 1 (CRHR1) positive neurons were detected with immunohistochemistry.

RESULTS
Serum HYD level was significantly increased (p < 0.01), and both ACTH and CRH were dramatically decreased (p < 0.01) in the AD model group rats compared with normal control rats at day 7. Catalpol treatment was able to improve the hormone secretion disorder in AD model group rats compared with the model group (p < 0.01 or p < 0.05) in particular at 21 days. Structure damage of hypothalamus in the AD rat as evidenced less CRHR1 positive neurons, rough endoplasmic reticulum dilation and degranulation, and mitochondrial swelling under electron microscope. Catalpol treatment at both high and low doses was able to alleviate the structure damage of the hypothalamus in the AD rats.

CONCLUSIONS
Catalpol could improve the endocrine function of the HPA and alleviate the structural damage of hypothalamus in AD rats.


There are an apparatus and a method for controlling at least one glow plug of a motor vehicle described below. The control of the at least one glow plug is effected dependent on the operating state of the internal combustion engine. The control is effected depending on a variable which is dependent on the exhaust gas temperature and / or dependent on the fulfillment of a fuel quantity condition and / or a time condition.


This research was conducted with the aim of knowing the effect of promotions, lazpaylater features, and self-control on consumer consumptive behavior at the Lazada online shop. The method used in this study is the quantitative method and the data collection techniques carried out are distributing questionnaires, interviews and observations. Respondents in this study were consumers who had purchased goods at the Lazada online shop around Medan. Withdrawal of the number of samples using the slovin formula, then the sample obtained is 100 respondents with α = 0.5 . The results of this study prove that partially the research variables, namely promotions, lazpaylater features and self-control have a significant and significant effect on the consumptive behavior of Lazada online shop consumers. The influence of the promotion variable and the lazpaylater feature are positive and self-control has a negative effect on the consumptive behavior of Lazada online shop consumers. Furthermore, simultaneously or together it gives the result that promotions, lazpaylater features and self-control have an effect and are significant on the consumptive behavior of Lazada online shop consumers


The structure of a circular jet, modified by placing grids of two different configurations near the nozzle exit plane, was investigated by using a single hot wire probe. An annular grid which perturbed mainly the axisymmetric shear layer and a circular disk grid which covered most of the potential core were used to modify the jet passively. Behind the annular mesh, the width of the shear layer is reduced and a significant decrease in turbulence intensity is observed. Spectra of the velocity fluctuation show the suppression of the formation of organised structures in the jet mixing layer. In contrast to the annular grid, the influence of the disk grid on the mean velocity and turbulence intensity is not as significant. Evidence for the presence of large scale structures downstream of the edges of the grids is presented. Introduction Turbulence control or management in different flows is a rapidly expanding field of research because of potential benefits in industry. In particular, in plane and axisymmetric jets, extensive investigations have been carried out by using active techniques for turbulence enhancement as well as suppression, but investigations using passive techniques are not as extensive. The main objective in jet turbulence control is to target and interfere with the organised vortical structures that are formed due to Kelvin–Helmholtz instability in the mixing layer. Tong and Warhaft [11] and Parker et al [8] obtained a significant reduction of turbulence intensity by placing a thin wire ring in the shear layer near the nozzle exit plane. The width of the shear layer was reduced and the spectra of velocity fluctuations indicated the suppression of organised large structures in the mixing layer of the jet. Stephens [9] and Stephens et al [10] used grids and honeycombs to completely cover the nozzle exit and obtained similar results. Burattini et al [2] suggested that the grids suppress the shear layer instability and damp the jet column instability. Another passive technique employed in a plane jet is to place a bluff body like a cylinder in the potential core and use the vortex shedding behind it as a feed back mechanism to control the shear layer instability [6, 3, 5, 1]. Antonini and Romano [1] disturbed a circular jet by placing a long, thin cylinder parallel to the nozzle exit plane and obtained an increase in mixing. In jet turbulence control using a grid, apart from the influence of the mesh size and wire diameter of the grid, the circular edge is also likely to have an impact on the jet development. By using wire screens to partially cover the test section of a wind tunnel, Oguchi and Inoue [7] produced a mixing layer similar to that developing behind a splitter plate. Smoke flow visualisation indicated the presence of large scale structures downstream of the grid in the mixing layer. When a thin wire was attached to the screen edge, vortex shedding behind the wire also dominated the flow. Use of a narrow rectangular mesh or a small diameter disk grid yielded a wake. Spectra of velocity fluctuations in the wake produced by a rectangular screen (Zhou and Antonia [12]) clearly showed the presence of organised vortical structures even though there was no primary vortex street. Hydrogen bubble flow visualisation (Finlay [4]) in the wake of a rectangular grid (Figure 1) shows the formation of large structures downstream. Figure 1: Hydrogen bubble flow visualisation of structures behind a grid (from [4]). The main aim of the present work is to investigate the effect of placing an annular grid and a disk grid at the nozzle exit plane on the development of a circular jet by using a single hot wire probe. The annular grid perturbs the initial shear layer and a small peripheral part of the potential core; the disk grid covers most of the potential core. Experimental Conditions The jet was produced by a 55 mm diameter (d) circular nozzle to which air was supplied by a variable speed centrifugal blower via a diffuser, settling chamber and contraction which had an area ratio of 85:1. Two annular and two disk grids were used in this Case Grid Wire dia. (mm) Aperture size (mm mm) Outer dia. (mm) Inner dia. (mm) 1 Annular 0.5 1.25×1.25 100 30 2 Annular 0.2 0.54×0.54 100 30 3 Disk 0.5 1.25×1.25 30 − 4 Disk 0.2 0.54×0.54 30 − Table 1: Summary of mesh geometry for disturbed flow conditions. study and Table 1 gives the details of the grid geometry, mesh and wire size. Hereafter, measurement conditions will be referred to as Cases 1, 2, 3 and 4. The grid was isolated from the body of the jet by mounting it on a separate frame which was placed at a distance of 2 mm downstream of the nozzle exit plane. Figure 2 shows the nozzle, the coordinate axes and the four grids. Measurements of the mean velocity (U) and the longitudinal velocity fluctuation (u) were made by using a single hot wire probe operated in a constant temperature mode. The hot wire, made of 90% Pt-10% Rh, had diameter was 2.5 μm and the wire length to diameter ratio was nearly 200. A height gauge with a resolution of 0.01 mm was used to move the probe in the ydirection. The hot wire signals were digitised using a 12 bit A/D converter and stored on a PC for further processing. Annular Grid Disk Grid


To understand sound-intensity measurement, it should be realized that sound intensity is sound-power flow per unit area in the direction of sound propagation. Sound intensity can be measured in fluids such as air or water. Generally measurements cannot be made inside a solid. However there may be ways of measuring sound intensity in a solid, if the solid is transparent. Also sound intensity can be computed in a solid and then measured in a surrounding fluid to collate with the calculated results. In general the measurement of sound-intensity is relatively new. It can be measured either as a vector in three or two dimensions or as a single vector component. These features are discussed, together with some examples of sound-intensity measurement. An important use of a single component of sound intensity is the measurement of the sound power of a noise source. Another use is locating the primary sources of noise in operating machinery. The full sound-intensity vector can determine the direction of a noise so...


This paper was conducted in the Kumaon Division of Uttarakhand with an objective to find out the information needs and the constraints faced by the farm women covering two blocks. From each block, two villages were selected randomly. By using Probability Proportional to Size sampling method, 25 percent of total farm women from each of the chosen villages were selected randomly. A sample of 120 respondents were included in the study. The results depicted that women were very much interested to know about treatment of animals and animal breeding in the area of dairy farming and also to know more about their health and hygiene. Major constraints expressed by farm women in accessing the information were traditional and cultural norms, domestic responsibilities, not willing to take risk, lack of awareness of the programmes running for the development and illiteracy. Unavailability of extension functionaries, lack of technical guidance, lack of required field staff and inadequate supporting facilities and services were the major technical/extension constraints. *Address for correspondence: Gaurav Papnai ICAR-Krishi Vigyan Kendra, Chinyalisaur, Uttarkashi 249 196, Uttarakhand, India E-mail: email@example.com INTRODUCTION Information irregularity at farm level has been observed as one of the main causes for low production and productivity efficiency. Access to accurate, reliable and timely information plays a significant role in the adoption of suitable technology. It enables individuals, groups and communities to realize their full potential and promote sustainable agricultural development (Ansari and Sunetha 2014). Women in India are major producers of food in terms of value, volume and number of hours worked almost 63 percent of all economically active men are occupied in agriculture as compared to 78 percent of women (Banerjee et al. 2016). Active participation of farm women is also increasing in agriculture and allied fields. Although women are involved in farming activities but their skills and knowledge about modern agricultural technologies are remaining extremely low. In order to improve agricultural productivity, the extension system will have to first acknowledge the contribution of farm women in agriculture and allied fields and then initiate appropriate steps for up scaling their knowl-


Financial analysis of banking activities, using a similar methodology, has different goals depending on the subject of the evaluator. Especially important is the financial analysis of banking activities in taking strategic decisions and the monitoring of their implementation today, when the formation of market relations in the country has passed a certain way in their development, it is however far from the concept - developed market.


Oral mucosal desquamation is a common scenario in a number of pathologic conditions, suchas chemical and electrical burns, allergic reactions, hormonal disorders, and mucocutaneous alterations. There are, to the authors' knowledge, only a few studies describing specific oral care products as a cause of mucosal desquamative lesions.3Y5 Eleven patients presented to our observation between September 2015 and February 2016, showing mucosal alterations of the oral vestibule, consisting of whitish-grey areas with detachment of a thin epithelial layer. These lesions were asymptomatic, and the underlying tissue appeared unaltered (Fig. 1). Every examined patient reported the use of the same toothpaste, recently put on the market (AZ Pro-Expert; Procter & Gamble, Cincinnati, Ohio). Samples of desquamated mucosa were retrieved from each patient with a gentle brushing action, and histological analysis was performed. The constant histological finding was represented by an alteration in the maturation process of the epithelium. The samples harvested were composed by desquamated keratinocytes, characterized by hypodysmaturation. Parakeratosis is a well-defined condition, showing the incomplete maturation of epidermal keratinocytes and an abnormal retention of nuclei in the stratum corneum, which appears thin and ready to exfoliate. Conversely, the pattern observed here indicates a stimulus to maturation hindering the complete growing phase, bringing anisocoric shapes of voluminous cells with big irregular nuclei (Fig. 2). Unfortunately, in the histological analysis, the underlying tissue conditions could not be examined because of the harvesting technique (full-thickness biopsies were not performed because they were not indicated both from clinical and ethical point of view). Furthermore, discontinuing the use of the aforementioned toothpaste resulted in rapid healing, with restitutio ad integrum, for all the patients. During the 1990s, a ''dentifrice reaction'' was identified after the use of toothpastes containing sanguinaria3; more recently, the acronym ''TIME'' (toothpaste-induced mucosal etching) was assigned to specific lesions, characterized by strong cellular edema, comparable with a chemical/physical insult.5 Although some evidence of mucosal alterations related to the use of oral care products is detectable in the unofficial literature, to date, no works clarify the etiological mechanism or pathophysiology of the lesions. Considering our cases, it must be noted that AZ Pro-Expert has a formulation with an extremely low water content (0.5%Y1%) if compared with other toothpastes (30%Y50%), to stabilize stannous fluoride in the compound. This feature could be a key to explain the uncommon mucosal response, more than a direct action of the stannous fluoride on the tissues. Hypersensitivity reaction could be reasonably excluded both for the lack of clinical signs on the underlying tissue and for the complete absence of eosinophils in the


The construction of a class of indecomposable representations of the Poincare group, using the Fell's formalism, is given. The application of these representations for a description of unstable particles of arbitrary spin is considered and various properties of unstable particles are analysed.


The problem of designing bounded distributed connectivity preserving control strategies for multi-agent systems is studied in this work. In distributed control of multi-agent systems, each agent is required to measure some variables of other agents, or a subset of them. Such variables include, for example, relative positions, relative velocities, and headings of the neighboring agents. One of the main assumptions in this type of systems is the connectivity of the corresponding network. Therefore, regardless of the overall objective, the designed control laws should preserve the network connectivity, which is usually a distance-dependent condition. The designed controllers should also be bounded because in practice the actuators of the agents can only handle finite forces or torques. This problem is investigated for two cases of single-integrator agents and unicycles, using a novel class of distributed potential functions. The proposed controllers maintain the connectivity of the agents that are initially in the connectivity range. Therefore, if the network is initially connected, it will remain connected at all times. The results are first developed for a static information flow graph, and then extended to the case of dynamic edge addition. Connectivity preservation for problems involving static leaders is covered as well. The potential functions are chosen to be smooth, resulting in bounded control inputs. These functions are subsequently used to develop connectivity preserving controllers for the consensus and containment problems. Collision avoidance is investigated as another relevant problem, where a bounded distributed swarm aggregation strategy with both connectivity preservation and collision avoidance properties is presented. Simulations are provided throughout the work to support the theoretical findings.


Metallurgical processes during welding produce residual stresses in different zones of the welded parts. Our recent works report the effect of residual stress redistribution in a relatively short, up to two weeks, period after the welding procedure. The hypothesis that the observed stress relaxation phenomenon is associated to the microstructure evolution that occur in the material after the end of the welding procedure was proposed. To prove this hypothesis a physical simulation of the influence of the welding thermal cycles on the base metal with GLEEBLE equipment was performed. Using SEM EBSD technique the variation of grain boundary misorientation and changes in the microstructure accompanied by the residual stresses redistribution in the first dais after welding were.


The objective of this research project is to determine the ability of Euler and Navier-Stokes codes to predict vortex/shock-dominated flow that is representative of modern fighter aircraft. The motivation for this project is fourfold: (1) current fighter aircraft are capable of operating beyond C(sub L(sub MAX)); (2) high angle-of-attack vortex/shock-dominated flows are not well understood; (3) current design methods are of the trial-and-error type; and (4) current data bases are inadequate for Computational Fluid Dynamics (CFD) validation. All data and results are presented in viewgraph format.


Estimation of Distribution Algorithms (EDAs) require flexible probability models that can be efficiently learned and sampled. Deep Boltzmann Machines (DBMs) are generative neural networks with these desired properties. We integrate a DBM into an EDA and evaluate the performance of this system in solving combinatorial optimization problems with a single objective. We compare the results to the Bayesian Optimization Algorithm. The performance of DBM-EDA was superior to BOA for difficult additively decomposable functions, i.e., concatenated deceptive traps of higher order. For most other benchmark problems, DBM-EDA cannot clearly outperform BOA, or other neural network-based EDAs. In particular, it often yields optimal solutions for a subset of the runs (with fewer evaluations than BOA), but is unable to provide reliable convergence to the global optimum competitively. At the same time, the model building process is computationally more expensive than that of other EDAs using probabilistic models from the neural network family, such as DAE-EDA.


the past and the present of the Roman Catholic, Uniate and Orthodox Churches of Eastern Europe and the former Soviet Union, that the picture is complex, that the difficuties facing these societies and their Churches in a post-Communist world are immense. Paradoxically, in some ways it was easier for a Christian to live out the life of faith under Communism, for the lines of battle were clearly drawn and the heroic and sacrificial were constantly demanded, whereas now in the emerging pluralist societiesof Eastern Europe and the Commonwealth of Independent States, the lines between the light and the dark are fudged, consumerism and relative freedom of choice seem not to demand heroism and sacrifice. Indeed such qualities as intransigence, inflexibility, and the psychology of clergy trained clandestinely for a situation where you have to improvise and often avoid official structures, can be a disadvantage when the Church is no longer cut off from society and can set up structures and lines of command. The complexity of Russian Orthodox-Roman Catholic relations and the place of the Uniate Churches in this picture are explored with precision by Desmond O'Grady. The solidarity between different Christian traditions brought about by persecution, when all were in the same boat, appears sadly to have disappeared with the advent of religious freedom, and the rise of nationalism is firing the flames of inter-denominational conflict. The Pope's vision for a spiritually united Europe and eventual full communion between Catholics and Orthodox is contrasted by the author with the bitter fights between Uniates and Orthodox in Ukraine, and increasing suspicion towards Rome on the part of the Moscow Patriarchate, which has interpreted the creation of Catholic structures within the Russian Federation as attempts to proselytize. The Turned Card ends, however, on an optimistic note. Despite the present social and political turmoil and conflict between Christian denominations in some post-Communist societies, Christianity still has a vital role to play in bringing about reconciliation, argues O'Grady, and can help dismantle 'walls more resistant than those of Berlin, walls of ethnic hate, religious resentment and hardcore egoism'.


The finite element method applied to the - turbulence model is used to investigate the two-stream turbulent mixing layer. Whereas the model is known as one of the most popular of the turbulence models to date, the model has yet to be applied to the classical mixing layer problem to the best of our knowledge. A transient - turbulence model in COMSOL version 3.5a is used to solve this problem. In this work, a new method for visualization of vortex-shedding is demonstrated by solving for the transient response with a uniform inlet velocity superposed with stream-wise fluctuating velocity components upon the individual streams. The random fluctuating velocity imposed is similar to velocity measurements encountered in previously reported experiments with user-controlled frequency and amplitude factors. This method predicts good agreement with the motivating literature but does not show self-similarity for the fluctuating terms until . The results show that the time- averaged results of a transient solution of this type will yield an identical result to the steady- state solution.


Preeclampsia remains to be an urgent problem in the modern medicine, the main reason for which is the lack of high efficiency of treatment. One of the few methods with proven effectiveness is the prophylactic administration of aspirin at the beginning of the second trimester of pregnancy. At the same time, microcirculation disorders that underlie the development of preeclampsia are pathogenetically significant for other gestational complications.The objective: a study of the effectiveness of aspirin prescription for the prevention of preeclampsia and other complications during pregnancy using the logistic regression method.Materials and methods. The control group included 43 pregnant women with clinical criteria for preeclampsia. Forty six pregnant women with risk factors for preeclampsia who took acetylsalicylic acid from the 16-18 weeks of gestation formed the I group, and 46 pregnant women with risk factors for preeclampsia who did not take acetylsalicylic acid were included in the the II group. In all patients, on the basis of anamnesis data, risk factors and the course of the second trimester of pregnancy were analyzed, their correlation analysis and the use of acetylsalicylic acid were carried out, logistic regressions and simple decision trees were constructed.Results. The proposed logistic regression models have demonstrated their veracity by confirming the influence of traditional risk factors for the development of preeclampsia. At the same time, the use of these models allowed not only to prove the preventive effect of aspirin on the development of preeclampsia (the coefficient is statistically significant, with a negative sign), but also the ability to reduce the severity of preeclampsia. In addition, the negative sign of the coefficient was obtained when studying the effect of taking aspirin on such complications of pregnancy as premature birth and fetal growth retardation.Conclusions. 1. The use of a database of patients, statistical and model analysis of this dataset, allows you to establish and evaluate the relationship, their statistical significance between different factors. Based on the results of the research we can say with great confidence about the significant effect of prophylactic aspirin intake on reducing the risk of preeclampsia. 2. Taking aspirin reduces the likelihood of fetal growth retardation and premature birth. 3. The use of assisted reproductive technologies is positively correlated with the risk of developing preeclampsia. The influence of other traditional factors on the development of preeclampsia was proved by the method of logistic regression, which confirms the veracity of the proposed statistical model.


The article highlights and criticizes two mutually exclusive approaches to understanding the administrative process that currently exist in Russia, which emasculate its complex content, predetermined by the Constitution of the Russian Federation. From the system analysis of art. 10, 18, 72, 118, 126, 132 of the Constitution of the Russian Federation the administrative procedure legislation of the Russian Federation is distinguished, which is considered as a single legal basis for the administrative proceedings carried out by the courts (including: the Supreme Court of the Russian Federation, courts of general jurisdiction, arbitration courts), and the administrative process carried out by the public administration (including: federal executive authorities, executive authorities of the subjects of the Russian Federation and local self-government bodies performing administrative and public functions, as well as organizations, which, by virtue of federal law, have the status of a state or other body for the purpose of performing certain administrative and public functions). With this approach, two components are distinguished in the structure of the administrative procedural legislation of the Russian Federation: 1) administrative-procedural legislation that forms the legal basis of judicial administrative proceedings; 2) administrative-procedural legislation that forms the legal basis of executive (non-judicial) judicial administrative proceedings. Developing the information-psychological approach developed in the theory of law, in relation to the scientific knowledge of the administrative process, administrative-indicating legal norms are distinguished, the analysis of which allows us to reveal the content, form and structure of the judicial administrative process, as well as the executive (non-judicial) administrative process and to establish an integrative relationship between them. Using such a scientific technique, the following is distinguished: 1) a group of administrative-indexing norms that establish discretionary (descriptive) information about judicial administrative cases; 2) a group of administrative-indexing norms that establish discretionary (descriptive) information about non-judicial administrative cases. By means of a differentiated analysis of the selected legal norms, it is argued: judicial and extrajudicial administrative cases are separated, differentiated concepts of administrative proceedings and administrative proceedings are introduced, the structure of judicial and executive (extra-judicial) administrative proceedings is revealed. Based on the developed scientific positions, the key proposals for the systematization of the judicial administrative process and the executive (non-judicial) administrative process in Russia are put forward. Summarizing the above, it is concluded that the presented integrative approach to understanding the administrative process and the proposals put forward on its basis for differentiated systematization of judicial and executive (extrajudicial) administrative process are the only true way to develop the Russian model of administrative process.


Although employer-sponsored insurance is the primary source of health insurance for non-elderly individuals, premium growth and federal health insurance reform, including tax credits to purchase individual insurance, might decrease employers' propensity to offer coverage. Using estimates from a model of employer-sponsored insurance take-up, we simulate the proportion of workers who hold coverage who would be willing to purchase individual coverage if their employers dropped this benefit. Additionally, we consider how take-up rates would increase given the availability of income-based subsidies for workers who lose insurance.


Cast irons are important engineering materials, which possess a wide range of attractive properties. Their properties are significantly dependent on the microstructure of the cast, cast iron components. A way of controlling the microstructure of cast iron is through the control of cooling rates during solidification. To control cooling rate mould properties are important. This paper presents the report of a study of the effects of additions of iron filings to green moulding sand on the microstructure of grey cast iron. Five sand samples were prepared with different Fe content ranging from 1 wt% to 5 wt%. A control sand sample, which had no iron content, was also prepared. The properties of the sand samples were tested and used to cast some grey cast iron samples whose microstructure were observed by optical microscopy. The results show that addition of Fe filing does not have any adverse effects on the properties of green moulding sand; however, the microstructures show a dependence on heat storage capacity of the mould.


The global market for telecommunication industries is expanding rapidly. This situation has also increased the competition among prepaid card service providers in this sector. In order to retain the customer, the service providers must be able to identify the customer needs. In this study, conjoint analysis is applied to examine the service attributes that become the student' preferences in choosing prepaid cards. Then, the cluster analysis is used to group the preferences based on the demographic aspects. The results show that the operator and signal strength are the most important service attributes for the students in Jakarta. Keywords: Preference, Prepaid Card Services, Conjoint Analysis, Cluster Analysis.


A computationally efficient recursive total least squares (RTLS) algorithm is developed for iteratively computing the TLS solution for adaptive FIR filtering with input and output noises. The developed algorithm is aimed at searching the minimum of the so-called constrained Rayleigh quotient (c-RQ) in which the last entry of the parameter vector is constrained to the negative one. The high computational efficiency of the developed algorithm is obtained by searching the minimal point of c-RQ alternately along every coordinate direction and using the well-known fast gain vector. In particular, the developed algorithm involves only the 8N + 19 MADs (number of multiplies, divides, and square roots). The performances of the developed algorithm are compared with the IP (inverse power iteration) and the well-known RLS algorithms via computer simulations.


2005 was China's Year of Reform, according to a high- ranking Chinese official. A year-end retrospect indicates that China is developing as rapidly as ever, but in a more holistic sense. In addition to promoting the pace of eco- nomic development and increasing material wealth, atten- tion is also being paid to the quality of development and to social equity, justice and harmony. This altered approach determines China's future development trend.


An investigation was carried out with 54 scavenging ducklings of three genotypes belonging to three age groups (6, 10 and 14 weeks) taking from 3 areas reared under two feeding regimes. The birds were sacrificed from farmer's house between 4.0 and 5.0 P.M. They were dissected to identify crop and gizzard contents (CGC). Cereal grains, bran, green forages, insects and worms were the main CGC and their composition varied significantly (p 0.05) on TME for the same period. It may be concluded that the scavenging feeds are deficient in CP, Ca and TP but excess in crude fibre. So, the concentration of the nutrients (except CF and ash) available to the scavenging ducklings under rural condition may be treated as below the suggested nutrient requirements for ducklings. DOI: http://dx.doi.org/10.3329/bjas.v43i3.21646 Bang. J. Anim. Sci. 2014. 43 (3): 185-191


Uniform nanorod and nanoplate structured Bi2S3 thin films were prepared on ITO substrates using a microwave-hydrothermal assisted electrodeposition method. The phase compositions, morphologies and optical properties of the as-deposited thin films were characterized by XRD, XPS, Field emission scanning electron microscope (FESEM), TEM and UV-Vis-Near-IR. Results show that the obtained thin films are composed of orthorhombic phase Bi2S3 with good crystallinity. With the increase in the hydrothermal temperature, the crystallinity of the obtained films gradually improves then decreases. The best hydrothermal temperature is 130 ℃. Compared with the band gap for Bi2S3 thin film by electrodeposition method, the band gap of the Bi2S3 thin film obtained from microwave-hydrothermal assisted electrodeposition method raises from 1.44 to 1.84 eV.


Received: 18/11/2022 The objective of this study is to test the reliability and significance of a research model of communication journalism on public administrative reform policies in Vietnam. The model was built on the basis of expert consultation and previous studies in the world. The survey tool was built using a 5-point likert scale, convenient sampling method, 260 samples of 4 subjects including journalists, officials and civil servants, business, citizen. The tests included reliability analysis of the scale (Cronbach Alpha), exploratory factor analysis (EFA), confirmatory factor analysis (CFA) and parallel structural equation model analysis (SEM). The results of this study imply that the application of a multivariate analysis model to evaluate the effectiveness of communication journalism on Vietnam's public administrative reform policies in particular and policy communication in general is appropriate. Revised: 28/11/2022


Boiling-water-reactor dynamic behavior is most sensitive to pressure variations at atmospheric pressure due to the strong dependence of saturation temperature on pressure. The two important pressure variation effects at atmospheric pressure are the variation of hydrostatic pressure within the core, which leads to a change in saturation temperature with position, and the pressure variations resulting from the acceleration of water by changing steam volume. A system of equations that takes into account these pressure effects in a natural- circulation boiling-water reactor was derived by means of conservation principles stated in integral form. The resulting equations were solved numerically. Sample calculations revealed no special tendency toward instability other than a form of hydraulic instability that does not depend on the inclusion of pressure effects in the model. (auth)


Endovenous laser ablation (EVLA) is a less invasive alternative to vein stripping. Outcomes seem equal to, or better than, those with stripping, with better quality of life scores in the post-operative period. EVLA has been shown to correct or significantly improve hemodynamic abnormality in patients with chronic venous insufficiency (CVI) with superficial venous reflux. Early reports suggest that endovenous ablation techniques, in contrast to surgical stripping, are associated with a low incidence of neovascularization. A variety of wavelengths are being used to perform EVLA. While the initial chromophore is water or hemoglobin, depending on the wavelength used, carbon appears to be a secondary but key chromophore that is probably independent of wavelength. The application of the principles of tumescent anesthesia to venous treatments, along with the development of endovenous ablation techniques, offer the possibility of treating the vast majority of patients with varicose veins in-office without general anesthesia or surgical incisions, while at the same time maximizing outcomes and minimizing recurrence.


of complex eigenvalues p &io with o being any real number, and B, satisfies leB1' 1 < Me"" for t 6 0; (H2) fand g are Cr+' with r 3 3 satisfying f(0, y) = 0, Df(0, 0) = 0, g(x, 0) =0 and Dg(0, 0) =0 for (0, y) and (x, 0)~ U, where D is the differentiation operator in (x, y). Given a triplet (r, x,,, y1 ) a solution (x, y)(t) of Eq. (1.1) is a solution to the Sil'nikov problem if the Sil'nikov conditions x(0) = x0 and y(r) = y, are satisfied. It is well known that such a solution exists and is unique with respect to the Sil'nikov conditions for r > 0, Ix0 1 d 6, and ly, 1 d 6, with a constant 6, being arbitrarily small but fixed. Also, as functions of t, r, x,,, and y,, x(t; r, x0, y, ) and y(t; r, x,,, y, ) are also c'+ I. Furthermore, there


The power supply system and power supply interlocking principles of the B_(23) mechanical refrigerator car are described. The problems existing in the power supply interlock control circuit are analyzed. And the measures for improvement are put forward.


In many inflationary models, a large amount of energy is transferred rapidly to the long-wavelength matter fields during a period of preheating after inflation. We study how this changes the dynamics of the electroweak phase transition if inflation ends at the electroweak scale. We simulate a classical SU(2){times}U(1)+Higgs model with initial conditions in which the energy is concentrated in the long-wavelength Higgs modes. With a suitable initial energy density, the electroweak symmetry is restored non-thermally but broken again when the fields thermalize. During this symmetry restoration, baryon number is violated, and we measure its time evolution, pointing out that it is highly non-Brownian. This makes it difficult to estimate the generated baryon asymmetry.


The purpose of this case is to present the portfolio level challenges facing a public pension fund director of real estate. Public pension funds typically rely on a small professional investment staff charged with recommending the real estate portfolio strategy to the board of trustees. Following the board's approval of the strategy, the staff is also charged with executing the strategy. In this case the director of real estate is preparing the board memo recommending the coming year's real estate investment strategy. Issues related to the overall real estate target allocation, recent market performance, investment-style targets, property type, and regional investment considerations all impact the recommendation.


The advancement of technologies and Information Systems (IS) associated with the search for success in the competitive market leads organizations to seek strategies that assist in acquisition, retention, storage, and dissemination of knowledge in the organization in order to be reused in time, preserving its Organizational Memory (OM). Organizational Memory Information Systems (OMIS) emerge as an enhancer of the OM, providing effective support and resources for the organization, assisting in decision making, in the solution of problems, as well as in quality and development of products and services. This article is an analysis of some OMIS selected from a literature review about its features and functionality in order to understand how these information systems are seen by the organizations. With this research, we realized that the relationship between OM and IS is still inexpressive, even with the existence of some cases of success in the use of OMIS in the literature. The literature reveals that an individuals' knowledge is not integrated in information systems management process in most organizations; much of this knowledge is generated in the organization retained in an individual himself/herself. It is easy to see that there is a need for strategies and mechanisms in the organization to stimulate and provide better knowledge sharing between individuals which, when associated to IS, allows greater control and effective use of Organizational Memory.


Toxicity of chemical substances should be determined for protecting biological environment. A Daphnia pulex is one of the indicator organisms for searching the toxicity, because the shape is changed depending on the toxicity. Conventional method for its observation has been performed under suppression of its movement in a small thin room with an ordinary optical microscope. There had been concern of the stress for the Daphnia pulex. The digital holography having the postfocusing ability was applied to it for a freely-moving Daphnia pulex. The digital holography was given a low-coherence light source and an in-line structure toward a practical on-site use with not-clean environment and vibration disturbances.


Disease‐modifying antirheumatic drugs (DMARDs) are the standard of care for rheumatoid arthritis (RA); however, studies have found that many patients do not receive them. We examined predictors of starting and stopping DMARDs among a longitudinal cohort of patients with RA.


When we are invited to 'tap spirituality in organisations' there is an enthusiastic response, because we are invited to imagine engaging with that spirituality which many value intensity, yet which may live as a hermit in the heart of lives in which much is rough and petty. Yet for some the response will be more cautious; they will feel that experience has proven that it is wise for spirituality to relinquish public ambition. Hence, while some will believe that spirituality can extend its domain on the basis of its intrinsic goodness, others will feel that such belief is naive.


Barrett's esophagus is a precancerous lesion of esophageal adenocarcinoma.With the increasing incidence of esophageal adenocarcinoma,pathological diagnosis of Barrett's esophagus attaches more attention.In this study,84 cases of Barrett's esophagus were randomly divided into experimental and control groups.In experimental group,staining was performed with 0.5% solution of methylene blue with a spray catheter.In control group,four-quadrant random biopsies were taken during routine endoscgrope.Finally,the clinical value of methylene blue-directed biopsies in pathologic diagnosis of Barrett's esophagus was evaluated.It provides theoretical guidance for endoscope biopsy diagnosis of Barrett's esophagus.


This thesis takes a look at the work of video artist Thirza Cuthand to rethink how resistance is used and discussed in a film studies context. Cuthand's work uses an intimate, honest and often humorous approach to explore her experiences as a Two-Spirited Butch Lesbian from Little Pine First Nation. Although the video work of Thirza Cuthand has been shown across the country and internationally in spaces such as the National Gallery of Canada and in festivals like Tribeca, MIX Brasil Festival of Sexual Diversity, and Inside Out, Toronto, this is the first in-depth exploration of her work that has taken place. It focuses on six of her short-length works: Working Baby Dyke Theory (1997), Anhedonia (2001), Untouchable (1998), Love & Numbers (2004), Colonization: the Second Coming (1996) and Boi Oh Boi (2012). This thesis uses Cuthand's work with two primary goals in mind. First, it uses Cuthand's videos to examine the usefulness of intersectionality as a framework worthy of greater consideration in a film studies context. Specifically, this thesis uses intersectionality to highlight the complicated ways in which power and resistance express themselves across different identity axes. Second, this thesis employs Michelle H. Raheja's concept of visual sovereignty to suggest that resistance need not be considered merely a reactive gesture but a generative one as well. In doing so, this thesis seeks to use Cuthand's videos to reorient discussions of resistance in order to challenge a self/Other binary.


The authors consider a new Ising model, with nearest-neighbour spin-spin interactions, on a self-avoiding-walk chain, where the walk itself is executed on a regular d-dimensional lattice. A Monte Carlo study for walks on a square lattice (d=2) has been made here, and a transition at a finite temperature has been observed. The transition temperature of the system has also been estimated using the virtual crystal approximation (for configurational averaging) and the Bethe-Pierls approximation.


Ultra-short period Galactic binaries are unique multi-messenger tracers of the Milky Way. They can be detected in large numbers through electromagnetic radiation by Gaia and through gravitational waves by the upcoming LISA mission. First, we revise the current census of known multi-messenger Galactic binaries by computing their GW signals using updated distances from the Gaia Data Release 2. Our work confirms thirteen guaranteed multi-messenger sources: nine AM CVns, three detached double white dwarfs (DWD) and one hot subdwarf. Next, we forecast the detection prospects for DWDs with both Gaia and LISA using a binary population synthesis technique. We predict respectively hundreds and tens of thousands detections by Gaia and LISA, with an overlap of several tens.  We show that synergies between Gaia and LISA observations of DWDs allow the study of the Milky Way baryonic structure. The success of this synergy is due to LISA's ability to localise binaries through virtually the whole Galactic plane, thus mapping its shape. While observations of LISA's electromagnetic counterparts observed by Gaia yield the information on their motion; tracing the underlying total enclosed mass. We envisage that multi-messenger observations will ensure the best science return of the LISA mission for Galactic studies.


The implementation of land reform and the introduction of the land market encourages the use of highly effective approaches to agricultural land management in the face of climate change. Agriculture is vulnerable to the effects of climate change due to extreme weather events, which intensify land degradation processes, such as water erosion and flooding. In such circumstances, the application of approaches to assessing the risks of flooding in the context of agricultural land management of territorial communities is relevant.

On the example of Slavska TG and Skolivska TG, the risk assessment of flooding of the Opir River and Stryi rivers (at the confluence of the Opir River) was carried out. The research was performed on the normative provisions of the national legislation of Ukraine, as well as Directive 2007/60 / EC and its guiding documents. The flood zones of the territories within Slavska TG and Skolivska TG, the areas of relevant floods and the amount of potential losses for agricultural lands under different flood scenarios have been identified.

It is proposed to develop and implement a number of measures to minimize the negative effects and losses associated with land flooding. Prospects for the application of the results in the development of land management documentation are considered.


We discuss the construction and factorization pattern of several resolvent polynomials that are useful for computing Galois groups of degree 15 polynomials. As an application, we develop an algorithm for computing the Galois group of a degree 15 polynomial defined over the 5-adic numbers. This algorithm is of interest since it uses substantially fewer resolvents than the traditional method for computing Galois groups. AMS Subject Classification: 11S15, 11S20


All producers, importers, and users of chemicals in the European Union (EU) will be required to register and in many cases seek authorization to produce or use chemicals. The major feature of this new legislation is that it shifts the burden of proof in the EU from the governmental bodies to the producers and users for generating toxicological data; information regarding the potential occupational, environmental, and public health impacts; recommended exposure limits; as well as specific guidance on how to safely use and dispose these chemicals for each "major use scenario". This presentation will cover the origin and basics of the EU REACH initiative, explore how it might affect US companies, both those exporting to the EU and those that do not, and also how the REACH initiative has the potential to radically change the practice of EHS sciences worldwide.


We studied composition, structure, microstructure, and magnetic properties of percolating (Ni-Fe)_ x (SiO_2)_1− x granular thin films. We found that the magnetic susceptibility increases and the coercivity decreases when increasing x toward x _ t , the critical metallic volume fraction for the metal-insulator transition, and the susceptibility decreases and the coercivity increases when increasing annealing temperature for x just below x _ t . Comparison of the microstructure and the magnetic properties suggests that the enhanced magnetic susceptibility for x just below x _ t is probably associated with the labyrinthine structure of the granular magnetic particles where there is an enhanced surface-to-volume ratio of the magnetic particles.


Retiform hemangioendothelioma (RH) is extremely rare, and often involves the skin and subcutaneous tissues of distal extremities in young adults or children. Since its first description by Calonje in 1994, only a few primary multiple cases have been described in the literature. We present a case of unusual primary multiple RH on forearm and neck occurring in a 56 years old female patient. The patient presented with a slow-growing cutaneous plaque-like lesion on her left forearm, followed by another lesion at the site of neck for several years. In the skin biopsy examination, a diagnosis of angiosarcoma with cutaneous metastasis was made based on multiple lesions at different anatomic sites and vasoformative growth pattern with anastomosing channels under the microscopy. However, postoperative histological diagnosis of the lesion was primary multiple RH by thoroughly microscopical inspection and the presence of thin-walled interconnecting vascular channels arranged in a retiform pattern and absence of lymph node metastasis. Despite wide surgical excision with tumor-free margin, the tumor recurred at the neck 3 months after surgery. The second local excision was performed. The patient was on regular follow-up for 18 months without additional treatments. There was no sign of recurrence or lymph node metastasis. Due to its rarity, multiple RH might be erroneously interpreted as angiosarcoma with metastasis by those who were not familiar with this condition, or conduce to aggressive postoperative treatment. Therefore, thoroughly microscopical inspection and a long-term follow-up are helpful for surgeons and pathologists to obtain an accurate diagnosis and avoid clinical over-treatment. Correspondence to: Dr. Zhi Li, Department of Pathology, The First Affiliated Hospital, Sun Yat-sen University 58, Zhongshan Road II, Guangzhou 510080, China, Tel: (8620) 8733 0890; Fax: (8620) 8733 1780


....................................................................................................... iii ACKNOWLEDGEMENT ................................................................................................. vi TABLE OF CONTENTS ................................................................................................... viii LIST OF TABLES ........................................................................................................ xi LIST OF FIGURES ........................................................................................................ xiv


The successful implementation of electronic congestion pricing is highly dependent on the identification and installation of appropriate technology. Several technologies exist in the market that differs according to vehicle tag type, transponder type, security strategy, cost and operating radio frequency. There are trade-offs with each technology, and very few studies presently exist that evaluate their performance under different conditions. Recent demonstration projects in Europe offer a unique opportunity to study key issues such as technology-related experiences, transactions, standardization and enforcement. This chapter discusses these experiences while identifying different performance criteria for evaluation. These performance measures are used in a formal evaluation framework based on the ELECTRE IV algorithm to rank different technologies. Such a framework complements the large body of work on congestion pricing, by providing an evaluation framework for streamlining technology investment decisions under different pricing schemes.


Chinese electric bus companies are expanding globally at a faster pace,with their advanced technologies and green mission.Japan-based Kyotokyukou Bus Incorporated,one of Japan's largest transit operations,has taken delivery of 5 Long Range Battery Electric Buses from BYD Company Ltd,the largest domestic auto-manufacturer and electric-bus manufacturer in China.T-he BYD electric buses will be operated in Kyoto,a well known bartleground for


Tang, G., Stewart-Smith, J., Plastow, G., Moore, S., Basarab, J., MacNeil, M. D. and Wang, Z. 2011. Optimizing a beef production system using specialized sire and dam lines. Can. J. Anim. Sci. 91: 353-361. Crossbreeding is an effective method for improving the efficiency of production in commercial cow-calf operations. It exploits available heterosis (hybrid vigour) and complementarity between different breeds or populations (lines). Before adopting a crossbreeding system, commercial cattle producers should evaluate available genetic resources and feasible crossbreeding systems, and choose one that is most beneficial for their own environment, resources, and management. This study compared profitability of alternative crossbreeding systems based on Beefbooster beef cattle breeding strains through computer simulation. Biological and economic data were collected from commercial customers of Beefbooster in Montana and western Canada, and breeding records from the database of Beefbooster, Inc. Three maternal strains (M1, M2 and M4) and two specialized paternal strains (M3 and TX), were evaluated with two simulated crossbreeding systems. System 1 uses a rotational cross between M1 and M4 with yearling crossbred heifers bred to M3 sires. System 2 is based on a three-strain rotation of M1, M2 and M4 with yearling crossbred heifers bred to M3 to facilitate ease of calving and crossbred cows bred to a classical terminal sire strain TX. Simulated base profit from system 2 was $29.57 greater ($215.21 vs. $185.64 yr-1 per cow) than from system 1.


Transcription by RNA polymerase is highly regulated via cis-acting signals on the template DNA and product RNA, as well as via trans-acting protein factors [1]. For example, bacterial RNA polymerase requires a σ factor to specifically initiate transcription at promoter sequences. Furthermore, transcription can be terminated intrinsically via a stable stem-loop structure on the nascent transcript followed by a uridine-rich sequence, or in response to termination factor ρ, an RNA-stimulated ATPase. Transcription is also extensively regulated during the elongation phase, a paradigmatic example of which is afforded by λN-mediated processive transcription antitermination [2]. During λN-mediated antitermination, phage protein λN, host factors NusA, NusB, NusE and NusG and a nut site on nascent RNA cooperate to render RNA polymerase termination-resistant. The structural basis of λN-mediated antitermination has so far remained elusive. We determined a crystal structure of a λN-NusA-NusB-NusE-nut site ribonucleoprotein complex and an electron cryo-microscopic structure of a complete transcription antitermination complex, comprising RNA polymerase, template DNA, product RNA including a nut site, all Nus factors and λN. We validated the modeled organization of the transcription antitermination complex by chemical cross-linking in combination with mass spectrometry. In the λN-NusA-NusB-NusE-nut site complex, the highly extended λN and nut site RNA interconnect NusA, NusB and NusE, forming a triangular assembly. This complex docks via the λN C-terminus and via an N-terminal domain of NusA next to the RNA exit channel on RNA polymerase. The architecture of the transcription antitermination complex suggests multiple mechanisms, by which λN re-programs the host transcription machinery and prevents termination, in agreement with structure-guided functional analyses. (i) The λN C-terminus clamps the RNA exit channel, probably indirectly stabilizing the DNA:RNA hybrid. (ii) λN seems to strategically re-position NusA and RNA-binding elements of RNA polymerase, re-directing nascent RNA and allowing a NusA RNA-binding domain to sequester the upstream branch of a terminator hairpin. (iii) The assembled λN-NusA-NusB-NusE-nut site complex may hinder RNA engagement of termination factor ρ and/or obstruct ρ translocation on the transcript. Our results reveal how, due to intrinsic disorder, λN can act as a multi-protein/RNA interaction hub and thereby mount a multi-pronged strategy to reprogram the Escherichia coli transcriptional machinery.


This article presents an etymological case study on Pre-Greek (PG): it analyzes about 20 words starting with the letter M that have been catalogued as or in the new Etymological dictionary of Greek (EDG), but for which alternative explanations are equally possible or more likely (discussing all instances would be tantamount to rewriting the dictionary). The article briefly discusses the EDG (for an in-depth appraisal the reader is referred to part one of the article) and then analyzes the individual words. This analysis is performed by giving an overview of the most important earlier suggestions and contrasting it with the arguments used to catalogue the word as PG. In the process, several issues of Indo-European phonology (such as the phoneme inventory and sound laws) will be discussed.


Taking Jixiang District as the example, and according to the two forms of flat slab and beam slab, this paper introduces the construction technology for the raft foundation from construction preparation, and construction process, etc., puts forward some problems that should pay attention to in the construction, and analyzes the construction effects.


A 88 year-old woman was referred to our center for 3 weeks of gastrointestinal bleeding and a spontaneous right rectus femoris hematoma. The prothrombin time (PT), activated partial thromboplastin time (aPTT), thrombin time (TT) and reptilase time (RT) were markedly prolonged ([Table 1][1]). Assays for coagulation factors V, VIII, IX and X were normal. A fibrinogen concentration of < 50 mg/dl was measured by Clauss method while fibrinogen concentration measured by radial immunodiffusion was 180 mg/dl. Following infusions of cryoprecipitate there was accelerated clearance of fibrinogen as measured by the Clauss method. An inhibitor of fibrinogen function was suspected.

View this table:

Table 1

When the patient's plasma was tested towards immobilized fibrinogen in ELISA plates, a concentration dependent specific binding of IgG was seen while under similar conditions control IgG had no significant binding ([Figure 1][2]). The IgG antibody was polyclonal comprising of both kappa and lambda subtypes.

![Figure][3]

The IgG fraction was purified on a Protein A column and the isolated IgG fraction prolonged the thrombin time of normal plasma in a concentration dependent manner. The effect of the isolated IgG fraction on fibrin polymerization was measured by monitoring the absorbance at λ390 in a spectrophotometer. The IgG inhibited fibrin polymerization in a concentration dependent manner. Control IgGs had no significant effect on polymerization under these conditions ([Figure 2][4]).

![Figure][3]

The immunologic specificity of antibody was tested in immunoblots of fibrinogen subjected to SDS-PAGE. The patients IgG reacted with fibrinogen in unreduced buffers. Under reducing conditions, the IgG reacted with Bβ and γ chains of fibrinogen while the control IgG did not ([Figure 3][5]).

![Figure][3]

The patient was treated with rituximab and steroids. After four, weekly doses of rituximab, fibrinogen levels by Clauss method normalized (450 mg/dl). There was no detectable antibody to fibrinogen and no further bleeding was noted.

Conclusion This is a description of a rare case of a polyclonal autoantibody to Bβ and γ chains of fibrinogen that inhibited fibrin polymerization leading to a severe bleeding diathesis.

Disclosures: No relevant conflicts of interest to declare.

 [1]: #T1
 [2]: #F1
 [3]: pending:yes
 [4]: #F2
 [5]: #F3


BACKGROUND
Out-of-hours primary care for people with intellectual disabilities (ID) involves different groups of health care professionals, who are often not familiar to one another nor to the specific health care needs of this vulnerable population. It is not known to what extend these specific health care needs or organizational factors influence the delivery of out-of-hours primary care for people with ID.

OBJECTIVE
The objective of this study is to explore the experiences of health care professionals regarding the medical content and the organizational context of out-of-hours primary care for people with ID.

METHODS
Semi-structured interviews were conducted with daily care professionals, triage nurses and general practitioners (GPs) involved in out-of-hours primary care for people with ID in the Netherlands. Interviews were thematically analysed for medical content and organizational context.

RESULTS
The analysis resulted in four interconnected themes: (i) uncertainties in the triage assessment of ID patients; (ii) confusion about inter-professional responsibilities; (iii) impact on routines and workflow concerning ID patients and (iv) constraints in the decision-making process. All issues raised were related to the organizational context.

CONCLUSIONS
Health care professionals involved in out-of-hours primary care for people with ID indicate that the quality of this care is more influenced by the organizational context than by the medical content. We recommend out-of-hours GP services and care provider services for people with ID to set standards for roles and responsibilities in order to facilitate health care professionals in delivering accessible and high-quality care to this vulnerable population.


This project provides compelling evidence that the clusterin, COMMD1 and ApoE proteins function in the quality control of the essential copper-transport proteins ATP7A and ATP7B. This knowledge is significant because variations in the clusterin, COMMD1 or ApoE genes may explain the variability of patient symptoms in the copper-transport disorders, Menkes and Wilson diseases.


Related-party transaction is transferring obligation or resources between listed company and its related-party or holding subsidiary company no matter collection of price or not. Related-party transaction represents a special form of transaction, whose feature is disguised, unfair and difficult to supervise. To enhance practical comparability of listed company public information, it is necessary to help the users of accounting statement understand the transaction exposure of related-party transaction more accurately in detail. Certified Public Accountants should try their best to supervise through auditing. At the same time, it is important to reinforce self-regulation and supervision of regulation structure, and at last,increase the punishment intensity of illegal disclosure.


Prevalence of Cryptosporidium species in water supplies of Amasya, Middle Black Sea, by Acid-Fast staining methods Zeynep KOLÖREN* Burak K. DELİOĞLU Ordu Üniversitesi Fen-Edebiyat Fakültesi Biyoloji Bölümü, Cumhuriyet Yerleşkesi, 52200, Ordu, TURKEY *Corresponding Author e-mail: firstname.lastname@example.com Journal of Applied Biological Sciences 5 (3): 79-82, 2011 ISSN: 1307-1130, E-ISSN: 2146-0108, www.nobel.gen.tr The goal of this study was to investigate the prevalence of Cryptosporidium spp. in environmental and drinking water supplies in Amasya area, Middle Black Sea, Turkey by Acid-Fast staining methods. A total of 100 water samples, including drinking and river water were collected and investigated for the detection of Cryptosporidium oocysts. All water samples were collected on a monthly basis from up to 10 discrete sampling sites in Amasya and its surroundings and boroughs in the period between September and August 2011. All water samples were purified by Al2(SO4)3-flocculation for water pellets. The resulted pellets were stained by AcidFast stain. Subsequently, all collected water samples were directly screened light microscopically for Cryptosporidium oocyst detection by AcidFast staining method. 78 (78%) out of 100 water samples were positive for Cryptosporidium spp, whereas there were not Cryptosporidium oocyst in drinking water by AcidFast stain. In this study has point out to assume contamination of Cryptosporidium spp.in this region and it provides to keep relation with the involving waterworks in Turkey to cut through the protozoa contamination problems


Objective To describe the epidemiologic characteristics of influenza-like illness(ILI) and predict the disease in Huangpu District,Shanghai City.Methods The surveillance data of ILI from 2004 to 2011 in the region,was used to estimate the out-patient visiting percentage and crude morbidity of ILI in the area.Two seasonal trend models were applied to predict the situation during the period of January to September in 2012 and compared with the surveillance data.Results The out-patient visiting percentage of ILI decreased from 2.06%(2 267 /110 201) in 2004 to 1.02%(1 433 / 139 833) in 2011(P for Cochran-Armitage Trend Test 0.001),with an average rate of 1.51%(14 083 /929 883) during the whole period.The peak rate was observed in summer and winter from 2004 to 2008(Z =-2.44,P = 0.015) and in winter and spring in 2009.A higher out-patient visiting percentage and crude influenza morbidity were observed in those under 15 years than in other age groups.The average relative and absolute error derived from the seasonal trend model based on moving average were 0.61% and 3.04,respectively,less than those(6.44% and 3.01,respectively) from the seasonal trend model based on seasonal index.Further,the predictive curve by the seasonal trend model based on moving average appeared much smoother and was more applicable in setting a warning threshold value and an action threshold value.Conclusions The out-patient visiting percentage of ILI was decreased over past 8 years in Huangpu District.The seasonal trend model based on moving average may be used for influenza alarming.


Abstract : A preliminary cost estimating procedure was developed using historical highway construction project bid data for the State of Alabama Highway Department (AHD). The preliminary cost estimating procedure developed requires only project length and preliminary engineering estimates of material quantity to calculate a project cost. This procedure has specific application in estimating future project costs for budgeting purposes. The procedure developed relied upon the fact that ninety percent of the bid total cost was comprised on one-third or less of the bid pay items. The dominance of a bid by specific pay items applies to large and small projects alike. The geographic location within the State of Alabama has a negligible effect upon the cost estimating procedure. The application of the preliminary cost estimating procedure to three distinctly different types of construction projects examined in this research confirm its usefulness. The preliminary cost estimating procedure developed for the AHD is workable and can be applied to a wide range of highway construction and maintenance projects. (Author)


We present a detailed analysis of the specific star formation rate – stellar mass (sSFR − M*) of z ≤ 0.13 disk central galaxies using a morphologically selected mass-complete sample (M* ≥ 109.5M⊙). Considering samples of grouped and ungrouped galaxies, we find the sSFR − M* relations of disk-dominated central galaxies to have no detectable dependence on host dark-matter halo (DMH) mass, even where weak-lensing measurements indicate a difference in halo mass of a factor ≳ 5. We further detect a gradual evolution of the sSFR − M* relation of non-grouped (field) central disk galaxies with redshift, even over a Δz ≈ 0.04 (≈5 · 108yr) interval, while the scatter remains constant. This evolution is consistent with extrapolation of the "main-sequence-of-star-forming-galaxies" from previous literature that uses larger redshift baselines and coarser sampling. Taken together, our results present new constraints on the paradigm under which the SFR of galaxies is determined by a self-regulated balance between gas inflows and outflows, and consumption of gas by star-formation in disks, with the inflow being determined by the product of the cosmological accretion rate and a fuelling-efficiency –
M ˙ b,halo ζ
M˙b,haloζ
. In particular, maintaining the paradigm requires
M ˙ b,halo ζ
M˙b,haloζ
 to be independent of the mass Mhalo of the host DMH. Furthermore, it requires the fuelling-efficiency ζ to have a strong redshift dependence (∝(1 + z)2.7 for M* = 1010.3M⊙ over z = 0 − 0.13), even though no morphological transformation to spheroids can be invoked to explain this in our disk-dominated sample. The physical mechanisms capable of giving rise to such dependencies of ζ on Mhalo and z for disks are unclear


In this study, we have found, by simply adjusting system temperature, two wetting transitions at different liquid–liquid interfaces in three liquid phases coexisting region of the system H2O+n‐tetradecane+diethylene glycol monohexyl ether (C6E2). When the temperature close to the lower critical consolute temperature, an intruding (or wetting) layer of the lower water‐rich phase is formed between the upper oil‐rich and the middle amphiphile‐rich phase, and, with only a small amount of middle phase, the middle phase is formed a lenticular droplet suspending on the interface between the upper and the lower phase. A wetting transition is occurred with increasing temperature and the intruding (or wetting) layer of the lower phase is contracted into several beads suspending on the interface between the upper and the middle phase. These suspending beads of the lower phase vanish as increasing temperature, however, the middle phase still forms a lenticular droplet. With further increasing temperature, before the upper critical consolute temperature is reached, another wetting transition is observed, i.e., the lenticular droplet of middle phase collapses and forms a thin layer separating the upper and the lower phase.


This chapter aims to provide broad principles of service development underpinning good neuropsychiatric care. Learning from a British service provision context has been utilized to articulate service design issues relevant to an international health development agenda. The chapter further aims to clarify the purpose and composition of a specialist and multidisciplinary neuropsychiatry team. A 'bridging model' is advocated for development of future services in order to embed a holistic care delivery approach into service planning. A three-tier model of service provision and referral pathways in the context of a typical resource-rich health economy are described. However, the key lessons from this chapter could be easily applied to international health contexts where health budgets may be very limited in terms of service provision and human resource development.


"Objective – The aim of this study is to identify how the strategy of online businesses can be improved to increase financial profits. The focus of this study is on online businesses selling flowers, taking into consideration the fact that the freshness of flowers does not last long, and that the price and quality of flowers fluctuates depending on climatic conditions. Methodology/Technique – The data used in this research is primary data, obtained by distributing questionnaires for market research, tested against 57 respondents. The respondents were selected using non-probability sampling with a purposive sampling technique. The results of the validation test r count > r table, with 5% significance, shows that businesses providing flower arrangements are in high demand. Findings – The results of the model business identification canvas and the profit and loss projections indicate that the choice of the business strategy series for cut flowers on each element is accurate. The results of the analysis of the strengths and threats also identifies that selling price varies depending on the types of flowers used in an arrangement, and accessories used. Novelty – This research studies how the types of flowers used, the design of an arrangement, accessories used, packaging, and family ownership of a business can effect the interest of potential customers in the Fiore shop in Afrodite. "


Aiming at the bad performance of EMI filter in the high frequency band, the non-ideal factors of common-mode chokes and the limitations of the existing high-frequency model are summarized. Considering the frequency characteristics of core material and the influence of parasitic capacitance, an improved cascaded Foster network model is established, and then the common-mode and differential-mode high-frequency equivalent circuits of EMI filter in lS0kHz-30MHz are developed. Furthermore, an EMI filter design method based on the optimization of the impedance characteristics of common- mode chokes is proposed. An experiment is carried out to verify the method by an 1.2SkW Boost PFC prototype. Results indicate that the device with the proposed EMI filter can pass the conducted EMI test successfully, and the design scheme can provide effective guidance for the remediation of conducted electromagnetic interference.


As reported by Malaysia Palm Oil Statistics, the production of palm biomass residues increased significantly from year to year. Thus, the utilization of these residues is very important in order to prevent waste and dump areas adjacent to the palm oil mills. Meanwhile, in order to increase the energy content per unit volume, briquetting technology is expected to fulfill this requirement by compacting biomass residues into form with higher density. In this project, the utilization of empty fruit bunch (EFB) is emphasized in briquette production. It is combined with mesocarp fibre in order to obtain the higher gross calorific value of briquette. The result shows that the briquette contains EFB fibre and mesocarp fibre (weight ratio 60:40) has the compressive strength and combustion characteristics which are competitive with local commercial briquette contains mesocarp fibre and shell (weight ratio 60:40). It is found that combustion rate belongs to briquette containing proposed mixture (EFB and mesocarp fibre) is higher than the rate belongs to another one, if both of them are produced under same compaction pressure. This gives a higher heat release from the combustion of proposed briquette. Besides, all the characteristics belong to briquette contains new mixture are found to be close to the minimum requirement for making commercial briquette which stated by DIN 51731.


We develop and test a probabilistic real‐time streamflow‐forecasting platform, Multimodel and Multiproduct Streamflow Forecasting (MMSF), that uses information provided by a suite of hydrologic models and satellite precipitation products (SPPs). The SPPs are bias‐corrected before being used as inputs to the hydrologic models, and model calibration is carried out independently for each of the model‐product combinations (MPCs). Forecasts generated from the calibrated models are further bias‐corrected to compensate for the deficiencies within the models, and then probabilistically merged using a variety of model averaging techniques. Use of bias‐corrected SPPs in streamflow forecasting applications can overcome several issues associated with sparsely gauged basins and enable robust forecasting capabilities. Bias correction of streamflow significantly improves the forecasts in terms of accuracy and precision for all different cases considered. Results show that the merging of individual forecasts from different MPCs provides additional improvements. All the merging techniques applied in this study produce similar results, however, the Inverse Weighted Averaging (IVA) proves to be slightly superior in most cases. We demonstrate the implementation of the MMSF platform for real‐time streamflow monitoring and forecasting in the Mara River basin of Africa (Kenya & Tanzania) in order to provide improved monitoring and forecasting tools to inform water management decisions.


Laf metor rotates exclusively in eountcrcleckwlse and is stowed de"'n by CheY whereas the Pef motor is bidirecrional and ChcY controls its relationat sense, In Es['heric'hia coli. it has becn cstabljshcd that phospho-CheY binds te thc Nterrninal residues of FliM (a component of the cyteplasmic flagellar motor), The fTiM gcncs for Pof and Laf have beell identified in the genome sequence of V atginot.vticus. The Pof FliM protcin has a well conserved N-terrninat CheY docking site, By contrast, LafFliM lacks rhis scqucncc and the rest of the pretein shows a relatively Iow similarity to that of the Pof counterpart. Tu furthcr understand how ChcY controls beth Pof ttnd Laf motor, wc analyzed FliM by comparative genomics. From about 3eO spccics we aligned about 150 HiM sequences unti then we found that FliMs can be divided into three types according


Do other people plan for this moment? I shift the hangers in the wardrobe though I already know there's no good suit, pristine for a smart exit. Cuffs are worn, collars rough at the back, and the lapels are all too wide, or too narrow, I don't know which, but I do know, like Goldilocks, they are not just right...


The present invention discloses a method and an interactive display system, image processing involving interactions when technical field, said method comprising the steps of: displaying moving images; capture trigger operation of the dynamic image; analyzing the trigger action, sends a corresponding trigger command; generating a dynamic image-based trigger action. The motion picture includes: surface wave effects and with the fish swimming in the water. Interactive display method and system of the present invention described can collect and analyze a trigger action audience realize highly interactive viewer, using fish vivid display skeletal animation of the dynamic image, and is capable of rippling and sparkling Lin The trigger operation of the display Lin and other special effects scenes, vivid and real, immersive. Easy to apply in the museum, museum planning, exhibition, company presentations and other scenarios attract audiences, increase presence.


@mapkyca Are they UK based or US based? I can reach out to the @AWS_edu to see if they have training partners they recommened (if


Objective To study the clinical and pathological characteristics of young and old patients with colorectal carcinoma. Methods From September 1999 to September 2004 clinical characteristics of 22 young and 56 old patients with colorectal carcinoma were analyzed retrospectively. Serum CEA and CA 242 levels were measured. p53 c-erbB-2 and CD44v6 protein were detected by immunohistochemical methods in all patients.Results No significant difference was found in sex and site of colorectal carcinoma between young and old patients.The rates of poor-differentiated group and advanced stage(Duke's C+D) in young patients were higher than those in old patients(P 0.05).The positive rate of CEA,CA242, p53,c-erbB-2,CD44v6 in young and old patients were 34.1%,56.1%,53.7%,65.1%,36.6% and 19.6%,23.2%,33.9%,37.5%,17.9% respectively.There were significant difference between young and old one in four items except CEA(P 0.05). Conclusion There are different clinical characteristics and biological behaviors between young and old patients with colorectal carcinoma.