Both human embryonic stem cell‐derived cardiomyocytes (ESC‐CMs) and human induced pluripotent stem cell‐derived CMs (iPSC‐CMs) can serve as unlimited cell sources for cardiac regenerative therapy. However, the functional equivalency between human ESC‐CMs and iPSC‐CMs for cardiac regenerative therapy has not been demonstrated. Here, we performed a head‐to‐head comparison of ESC‐CMs and iPSC‐CMs in their ability to restore cardiac function in a rat myocardial infarction (MI) model as well as their exosomal secretome. Human ESCs and iPSCs were differentiated into CMs using small molecule inhibitors. Fluorescence‐activated cell sorting analysis confirmed ∼85% and ∼83% of CMs differentiated from ESCs and iPSCs, respectively, were positive for cardiac troponin T. At a single‐cell level, both cell types displayed similar calcium handling and electrophysiological properties, with gene expression comparable with the human fetal heart marked by striated sarcomeres. Sub‐acute transplantation of ESC‐CMs and iPSC‐CMs into nude rats post‐MI improved cardiac function, which was associated with increased expression of angiogenic genes in vitro following hypoxia. Profiling of exosomal microRNAs (miRs) and long non‐coding RNAs (lncRNAs) revealed that both groups contain an identical repertoire of miRs and lncRNAs, including some that are known to be cardioprotective. We demonstrate that both ESC‐CMs and iPSC‐CMs can facilitate comparable cardiac repair. This is advantageous because, unlike allogeneic ESC‐CMs used in therapy, autologous iPSC‐CMs could potentially avoid immune rejection when used for cardiac cell transplantation in the future. Stem Cells 2017;35:2138–2149


Microphone array technology has been proposed for various audio, teleconference, hearing aid and voice recognition applications. By forming a focused beam toward the desired speech source, attenuating background noises and rejecting discrete spatial interferers, a microphone array can enhance the signal-to-noise-ratio (SNR) in a noisy environment with notable improvement in speech intelligibility. At the threshold of intelligibility, a one dB improvement in SNR can increase 10-15% speech intelligibility. It is also known that increasing SNR can result in significant improvement in the recognition rate of various automatic voice recognition systems. We propose a novel electronically steerable microphone array based on the maximum energy (ME) concentration criterion, which results in high SNR in rooms with reverberations and competing interferences. We present a prototype PC-based microphone array system designed for hearing aid applications but also applicable to other tasks.


In this article, a set of sensors is constructed via the pinning observability approach with the help of observability criteria given in [1] and [2], in order tomake the given Boolean network (BN)be observable. Given the assumption that system states can be accessible, an efficient pinning control scheme is developed to generate an observable BN by adjusting the network structure rather than just to check system observability. Accordingly, the sensors are constructed, of which the form is consistent with that of state feedback controllers in the designed pinning control. Since this pinning control approach only utilizes node-to-node message communication instead of global state space information, the time complexity is dramatically reduced from <inline-formula><tex-math notation="LaTeX">$O(2^{2n})$</tex-math></inline-formula> to <inline-formula><tex-math notation="LaTeX">$O(n^2+n2^d)$</tex-math></inline-formula>, where <inline-formula><tex-math notation="LaTeX">$n\, {\text{and}}\, d$</tex-math></inline-formula> are respectively the node number of the considered BN and the largest in-degree of vertices in its network structure. Finally, we design the sensors for the reduced D. melanogaster segmentation polarity gene network and the T-cell receptor kinetics, respectively.


This paper presents a novel algorithm for the integer ambiguity resolution problem, which can be used for attitude determination in vehicle navigation. During the development the main goal was to give a fast and reliable solution for a well-known problem. To reach these requirements additional sensors are involved. The result is an algorithm which needs only some seconds to initialize and after that it is able to give precise and reliable attitude information. The results of the algorithm were tested on real-time data.


* Introduction Barbara Harriss-White and Judith Heyer * Primitive Accumulation and Capitalist Development in Neoliberal India: Mechanisms, Resistance, and Persistence of Self-Employed Labour Shapan Adnan * Regional Patterns of Agrarian Accumulation in India Jens Lerche * Agrarian Relations and Institutional Diversity in Arunachal Pradesh Deepak Mishra * First Transaction, Multiple Dimensions: The Changing Terms of Commodity Exchange in a Regulated Market in Madhya Pradesh Mekhala Krishnamurthy * The Political Economy of Microfinance and Marginalised Groups: Implications of Alternative Institutional Strategies D. Narasimha Reddy * Labour in Contemporary South India Isabelle Guerin, G. Venkatasubramanian and Sebastien Michiels * Emerging Spatio-Technical Regimes of Accumulation in the Globalising South and Implications for Labour M. Vijayabaskar * Commodification, Capitalism and Crisis Umar Salam * A Heterodox Analysis of Capitalism: Insights from a Market Town in South India after the Green Revolution Elisabetta Basile * Money Laundering and Capital Flight Kannan Srinivasan * Power Hungry: The State and the Troubled Transition in Indian Electricity Elisabeth Chatterjee * Technology and Materiality: South Asia in the 21st Century Sanjeev Ghotge


A clinical and statistical Analysis was performed on 1149 cases of anorectal disease which were
experienced at the Department of General Surgery, College of Medicine. Seoul National University from Jan. 1963 till Dec. 1972. The results were as follows: 1. The admission rate was 14.4% of total new patients, and 45.3% of anorectal diseases in Out-Patient Clinic. It shows the tendency of yearly increment since 1969. 2. The peak incidence was in the age group of 30 to 39 years in 29.9%, and 23.7% in the age group of 20 to 29 years. 3. The sex distribution was 807 in males and 342 in females with a ratio of 2.36 : 1 male preponderance was observed. 4. The incidence by month revealed the highest in July, and low in May and June. 5. The most frequent disease was hemorrhoid(42.9%), and followed by rectal cancer (17.6%). anal fissure and fistula (118%). 6. The admission rate of hemorrhoid was 21.7%, and the highest incidence in the age group of 20 to 39 years was noted. Male preponderance was observed with the ratio of 2.5 : 1. 7. The admission rate of hemorrhoid shows tendency of yearly increment since 1969, and the highest incidence in January: 24.1% of hemorrhoid were combined with other anorectal diseases. 8. The highest incidence of rectal cancer was in the age group of 50 to 59 years, and the average was 47.9 years. Male preponderance was noted with the ratio of 162 : 1. 9. Anal fistula was most frequently observed in the age group of 20 to 29 years, and male preponderance was noted with the ratio of 2.9 : 1. The admission rate of anal fistula was 19.8%, and 35.3% of the cases were found with hemorrhoids. 10. Among 1149 cases of anorectal diseases, 6 cases (0.52%) were expired, all these cases were observed in the male babies who had imperforate anus.


THE results obtained so far with streptomycin an various forms of tuberculosis have shown that, while it has only limited qualities as a specific drug, it is capable of profoundly modifying the course of the disease. It offers, therefore, opportunity to study aspects of the evolution of the disease which were hitherto unknown. Acute miliary tuberculosis was diagnosed in the following case 8 weeks before the delivery at term of an infant who has apparently remained free from the disease, the mother's life having been prolonged by treatment altogether for 19 weeks.


Objective:To study and evaluate the application of total hip replacement with a small skin incision.Meth- ods:From March,2004 to June 2006,60 cases hip joints were replaced by titanium alloy or cobalt,chromium and molybde- num artificial ones with small skin incision.Results:The average operation time of all 60 cases of total hip replacement was 75min (68-132min),the average incision length 6.5cm (6-8cm),intraoperative and postoperative blood loss 260ml (160-840ml).Conclusion:The total hip replacement through a small skin incision can have less tissue damage,less op- eration time and less operation blood loss.The operation method is an innovational and perfect and thus worthy of applying.


Brown adipose tissue (BAT) dissipates energy in the form of heat through uncoupled respiration. Brown adipocytes originate from different precursor cells and can be induced by various stimuli. Pharmacologically induction of BAT thermogenesis has been shown to be a promising treatment for obesity‐related metabolic disease. In this study, we investigated the potential role of berberine hydrochloride (BBR), a naturally occurring plant alkaloid, in activating brown fat adipogenesis.


We consider flight control with control effector fault detection and reconfiguration of a tailless aircraft. We extend an earlier continuous time multiple and simultaneous actuator fault detection observer. This observer was designed by minimizing the condition number of the observer modal matrix over the eigenvector free parameters. Our contributions include (1) extending the fault detection observer to the unified delta operator model that is valid for both continuous time and sampled data operation, (2) proposing a new less conservative bound on the observer residuals that is an explicit function of the observer eigenvalues and eigenvectors, and (3) optimizing over both eigenvalues and eigenvector parameters. Then, we propose a reconfigurable control scheme by combining the new fault detection observer with our earlier eigenstructure assignment flight controller. We consider symmetric lock in place failures of either the elevons or the all moving tips for the Innovative Control Effectors tailless aircraft. We present simulation results using the linearized lateral dynamics of the tailless aircraft. Our results show that our new fault detection observer has both smaller gains and condition number than an observer designed using the earlier method. Furthermore, we show that an all moving tip failure causes the aircraft to become unstable whereas our eigenstructure assignment reconfigured flight control system yields responses that are similar to the unfailed responses.


Lloyd Parks: former Dean of the College of Pharmacy at OSU (pp. 6, 13)
 -- Harold Enarson: President of Ohio State (pp. 12-15)
 -- Edward Jennings, President of Ohio State (pp. 12-13)
 -- E. Gordon Gee: President of Ohio State (pp. 12-13)
 Albert Kuhn: Provost (p. 15)
 -- Ann Reynolds: Provost (p. 15)
 -- Diether Haenicke: Provost (p. 15)
 -- Miles Brand Provost (pp. 15-16)


This paper analyzes unstable wrecked cause in 3 #~4 # intersection of shaft bottom in Guhanshan coal mine,rational all-closed support is adopted with rapair and gains good result of support.


This paper examines the politicisation of the senior civil service, i.e. the management positions of South Africa's public service, especially the affirmative action policy as a strategy to deal with the apartheid legacy in the country. The author argues that there is an attempt to re-politicise the current public service but that this poses a dilemma for the ruling African National Congress (ANC). 'Politicisation' is examined from three angles : politicisation as participation in the political decision-making; as partisan control over the bureaucracy; and as political involvement of public servants in a country's politics (Rouban, 2003). However, the contested meaning and lack of consensus on the 'politicisation' of the public service or public bureaucracy in South Africa is acknowledged.
To examine the 'political-administrative interface' (relationship between elected and appointed officials), the article has relied on several research methods including an analysis of official documents, policies, legislation, and media reports. The international literature on the politicisation of the civil service (especially by Suleiman, 1974, Aberbach, et al, 1981, and Rouban, 2003) also helped the author to understand South Africa's situation. The article's argument also relies on data from the author's recent doctoral study (Maphunye, 2002), which gave indications of the perceptions of politicisation amongst senior public servants in some government departments with strong indications amongst some that the South African public service was becoming increasingly politicised; some preferred a more professional public service as in the British tradition of the Civil Service College or the French ENA (Ecole National d'Administration). The paper concludes with an observation that the politicisation of the senior positions of the South African public service might be linked more to Rouban's (2003) second observation of partisan control over the bureaucracy than it is to his other two criteria. Although there is no stipulated policy to enforce such partisan control of the bureaucracy, the top echelons of the public service might be differently politicised or occupied by skilled pro-ANC individuals though the use of affirmative action policy. But it is also possible that politicisation occurs partly because since the ANC took power it has embarked upon a particular project of transformation, which seems to be abolishing any sharp divide between party and state.


Guiding-center simulations of stormtime transport of ring-current and radiation-belt ions having first adiabatic invariants μ ≳ 15 MeV/G (E ≳ 165 keV at L ∼ 3) are surprisingly well described (typically within a factor of ≲ 4) by the quasilinear theory of radial diffusion. This holds even for the case of an individual model storm characterized by substorm-associated impulses in the convection electric field, provided that the actual spectrum of the electric field is incorporated in the quasilinear theory. Correction of the quasilinear diffusion coefficient DLLql for drift-resonance broadening (so as to define DLLrb) reduced the typical discrepancy with the diffusion coefficients DLLsim deduced from guiding-center simulations of representative-particle trajectories to a factor ∼3. The typical discrepancy was reduced to a factor ∼ 1.4 by averaging DLLsim, DLLql, and DLLrb over an ensemble of model storms characterized by different (but statistically equivalent) sets of substorm-onset times.


A theoretical and numerical analysis is carried out for turbulent collisionless shocks mediated by the ion-Weibel instability during high-velocity plasma collisions. We develop a simple model based on the coalescence dynamics of the ion current filaments, which predicts the spatio-temporal evolution of the magnetic fluctuations formed in the upstream plasma region. From comparison with particle-in-cell simulations, our model is shown to correctly capture the magnetic-field and ion-beam properties during the early-time shock propagation.


High boost pressure is required to increase the specific output power of diesel engines. The pressure ratio of compressors for turbochargers has been increased to meet these engine requirements. IHI developed a new turbocharger, AT14 mounting a high pressure ratio centrifugal compressor, for 500 kW class diesel engines. In high pressure ratio centrifugal compressors, it is expected that the complicated flow characteristics related to occurrence of shock wave will deteriorate compressor efficiency and operating range. To avoid these problems, several countermeasures were taken in the aerodynamic design of AT14 centrifugal compressor. Newly designed compressors were realized with the expected performance, stage pressure ratio, and efficiency. This paper outlines the aerodynamic design of the centrifugal compressor for AT14.


This work addresses the effect of ultraviolet radiation of wavelengths longer than 250 nm on Si-CH3 bonds in porous low-k dielectrics. Porous low-k films (k = 2.3) were exposed to 4.9 eV (254 nm) ultraviolet (UV) radiation in both air and vacuum for one hour. Using Fourier Transform Infrared (FTIR) spectroscopy, the chemical structures of the dielectric films were analyzed before and after the UV exposure. UV irradiation in air led to Si-CH3 bond depletion in the low-k material and made the films hydrophilic. However, no change in Si-CH3 bond concentration was observed when the same samples were exposed to UV under vacuum with a similar fluence. These results indicate that UV exposures in vacuum with wavelengths longer than ∼250 nm do not result in Si-CH3 depletion in low-k films. However, if the irradiation takes place in air, the UV irradiation removes Si-CH3 although direct photolysis of air species does not occur above ∼242nm. We propose that photons along with molecular oxygen and, water, synergistic...


As this book has considered throughout, even a cursory look at any number of individual collectors and institutional libraries in the sixteenth and seventeenth century testifies to the centrality of secondhand books and therefore the importance of the second-hand book trade to their acquisition. As this book has done, piecing together patterns of ownership and acquisition through second-hand books will add ever more detail to ones understanding of intellectual reception and distribution in the early modern period. The books acquired by Chetham's Library represent such a 'multiplicity', and this book has explored them in such a way as to unpick the factors at work and to contribute to the large number of scholarly debates in the field. This book has to some extent sought to distance itself from identification solely with the field of book history.Keywords: acquisition; Chetham's Library; history; libraries; secondhand books; seventeenth century


This paper studies the problem on the estimate one-two-sided confidence intervals for mean of spectral reflectance of the vegetation. For this, the theory and methodology of mathematical statistics, algorithms and technologies of remote sensing, and a wide review of modern scientific literature are involved. As a result, for mean of spectral reflectance of the vegetation was estimated left-right-two-sided confidence intervals under realistic, optimistic, and pessimistic scenarios. And left-right-two-sided inequalities are given for mean of spectral reflectance of the vegetation.


Protein Z-dependent protease inhibitor (ZPI), a serpin family protein, together with its tightly bound vitamin K-dependent protein cofactor, protein Z (PZ), function to rapidly and specifically inhibit membrane-bound FXa. Along with antithrombin, tissue factor pathway inhibitor (TFPI), and activated protein C (APC), the ZPI/PZ complex comprises one of the major endogenous anticoagulants in human plasma. Recent findings showing that ZPI/PZ regulates prothrombinase activity and that ZPI/PZ gene knockout partly restores hemostasis in a hemophilia mouse model have suggested that the neutralization of ZPI/PZ anticoagulant function could provide an alternative therapy for hemophilia treatment. Compared with other alternative therapies currently in development that target APC, TFPI, and antithrombin anticoagulants, anti-ZPI/PZ therapy is expected to be safer and similarly effective. Recent progress in the development of potent, specific ZPI/PZ antagonists should enable testing of this potentially safer therapy in a hemophilia mouse model. *Correspondence to: Department of Periodontics, University of Illinois at Chicago, 801 S. Paulina St., Chicago, IL 60612, USA, E-mail: firstname.lastname@example.com


Production of faecal pellets by the herbivorous estuarine copepodGladioferens imparipes, and the rate at which the pellets sink through a water column, were investigated in the laboratory. Pellet production rate, at excess food concentration, varied among food types, with a maximum rate of 3.2 pellets h –1 copepod –1 when copepods were fed on the diatom Skeletonema costatum, and a minimum of 1.5 when fed on the chlorophyte Chlamydomonas globosa. Pellet production rates may have reflected feeding prehistory and related effects on food preference and ingestion rates. Settling rates ranged from 2.0 m day –1 for pellets produced on the thecate dinoflagellate Scrippsiella sp. to 71.8 for pellets produced on S. costatum. The estimate of settling rate was strongly influenced by the method used to measure it and measure pellet density. Application of the laboratory results to average copepod densities in the Swan River estuary suggested a conservative estimate of production of 360 pellets L –1 day –1 , or 8 ˜g C and 1 ˜g N, given appropriate food conditions. With a conservative estimate of settling rate at 6.3 m day –1 , pellets would easily reach the sediments within a tidal cycle in many parts of the Swan River estuary.


Abstract : This article critically examines realism and its relationship to national security policy. Rather than focus on individual realist authors, their ideas are synthesized here into a general interpretation of the field and integrated with the strong, symbiotic relationship between realist thought and national security policy. This article outlines the realist argument and focuses on four premises -- states, anarchy, interests, and power -- and illustrates the key differences between realism and other perspectives. The third section evaluates the usefulness of realism in terms of framing enduring security issues, and the final section discusses the future of realist thought with respect to framing emerging security issues. Accepting the tenets of realism is an act of humility -- a rare commodity in international affairs but a useful one nonetheless. American policymakers will eventually come to it, even if they do so reluctantly. Is realism in our future? The answer is yes. Advances in technology, health care, and communications are shaping the world we live in. Yet beneath it all, international politics has not changed significantly since Thucydides. In spite of economic interdependence, global transportation, and the information revolution, we live in a world where states must look out for themselves. As long as that holds true, statesmen are well advised to frame policy responses in terms of interests; no other tradition does that better than realism. In so doing, they ought to remember: a foreign policy based on a realist assessment is neither moral nor immoral but merely a reasoned response to the world about us.


We present a very general language for expressing tactic programs. The paper describes some essential tactic combinators (tacticals), and gives them a formal semantics. Those definitions are used to produce a complete calculus for reasoning about tactics written in this language. The language is extended to cover structural combinators which enable the tactics to be precisely targeted upon particular sub-expressions.


This article was originally presented as a keynote Address at the University of KwaZulu-Natal's Language Planning and Development Office (ULPDO) language symposium from 19-20 October 2015 at the Unite Building, Howard College, Durban, on the theme: Advancing the Intellectualization of African Languages in Higher Education. The position paper examines the challenge of how to intellectualise African languages and bring them up to speed with the linguistic techniques of modernity and advanced contemporary thought.


Abstract Laminar burning velocities of chlorinated methanes, trichloroethylene, and chloro-benzene in mixtures with methane and air were measured using the Bunsen cone method. The effects of mixture composition and precombustion temperature on the measured flame velocities were determined.


Дисертація на здобуття наукового ступеня кандидата психологічних наук за спеціальністю 19.00.03 – психологія праці, інженерна психологія. – Інститут психології імені Г. С. Костюка НАПН України. – Київ, 2014.

V.V. Kirichenko. The Development of the Personal Identity in the Process of Occupational Adaptation. - Manuscript.
The dissertation for the PhD in Psychology, specialty 19.00.03 – labor psychology, engineering psychology. – Institute of Psychology G.S. Kostiuk NAPS of Ukraine. – Kyiv, 2014.
In the thesis had developed a theoretical model of strategic and typological differences of worker's personal identity in the process of professional adaptation. Based on the results of the empirical research, had singled out the basic strategies of adaptation to a professional environment. The differences of people's personal identity have been analyzed with the focus on their situationally-adaptive, default and subject-value strategies of professional adaptation.
The general patterns of employees who work with people and those who work with machines has been defined in the process of professional adaptation. The comparative analysis of the major structural components of personal identity on the normative-orientation, search, reflexive and stage of development value has been made.
Keywords: the subject of labor, the strategy of professional adaptation, the professionally important qualities, value consciousness, personal identity, personal dispositions.


Postoperative pain is an important adverse event following inguinal hernia repair. The aim of this trial was to compare postoperative pain within the first 3 months and 1 year after surgery in patients undergoing open mesh inguinal hernia repair using either a self‐gripping lightweight polyester mesh or a polypropylene lightweight mesh fixed with sutures.


The produced sugar, as the final product in sugar production technology, has to contain as low non-sucrose compounds with coloured matters as possible. Ultrafiltration and nanofiltration could be one of the solutions for a more effective separation of non-sucrose compounds from intermediate products from which sucrose directly crystallises. The separation of non-sucrose compounds by ultra- and nanofiltration is investigated on syrup solution with 40% d.m. content, which is an intermediate product in the phase of sucrose crystallisation. Further, this paper investigates variables in the ultrafiltration and nanofiltration of syrup solutions, such as variations in pore sizes of the polymer membranes, syrup temperatures, syrup flow rates and transmembrane pressures. During ultrafiltration, under the investigated conditions; permeate flux is about 10 times less than water flux (150 m-2h-1) on the first membrane and 8 times less than water flux (285 m-2h-1) on the second membrane, while the nanofiltration perme...


We describe the preliminary design of the proposed Heterodyne Instrument for FIRST (HIFI). The instrument will have a continuous frequency coverage over the range from 480 to 1250 GHz in five bands, while a sixth band will provide coverage for 1410 - 1910 GHz and 2400 - 2700 GHz. The first five bands will use SIS mixers and varactor frequency multipliers while in the sixth band a laser photomixer local oscillator will pump HEB mixers. HIFI will have an instantaneous bandwidth of 4 GHz, analyzed in parallel by two types of spectrometers: a pair of wide-band spectrometers (WBS), and a pair of high- resolution spectrometer (HRS). The wide-band spectrometer will use acousto-optic technology with a frequency resolution of 1 MHz and a bandwidth of 4 GHz for each of the two polarizations. The HRS will provide two combinations of bandwidth and resolution: 1 GHz bandwidth at 200 kHz resolution, and at least 500 MHz at 100 kHz resolution. The HRS will be divided into 4 or 5 sub-bands, each of which can be placed anywhere within the full 4 GHz IF band. The instrument will be able to perform rapid and complete spectral line surveys with resolving powers from 103 up to 107 (300 - 0.03 km/s) and deep line observations.


tests of soils were performed in three areas selected according to the ne cessity to take into consideration diversity of soils. The researchers were taking into account the character of the ground, and soil type and class. The tests were carried out for soil classes II–VI, specified in the soil classification map as brown or podzolic soils (AB, A, B), consisting of sands, clays or loess.


Attempts were made to evaluate possibilities of adding water soluble chitosan to milk for improving functionality of milk, and physico-chemical and sensory properties of chitosan added milk were studied. pH and acidity of milk with ethyl alcohol washed chitosan were close to those of control. Color and consistency of chitosan added milk were better with chitosan of lower molecular weight than with high molecular weight. Chitosan of high molecular weight resulted in increased consistency and browning of milk. Milk with less than 1.0% chitosan could be sterilized at for 15 sec. with minimum protein coagulation and increase of consistency. Low molecular weight chitosan accelerated the growth of Bifidobacterium bifidum, showing 10 times more cell population after 32 hrs incubation. Sensory tests showed that adding chitosan to the regular city milk resulted in significant difference in color and chemical off-flavor(p, but changed rapidly after 16days storage at . Bacterial counts increased when storage temperature was high, and the growth of bacteria was delayed in coffee milk with chitosan.


PURPOSE
The treatment of ovarian cancer continues to pose a challenge especially through the development of platinum-resistant disease and still has the highest mortality rate among gynecologic cancers. Patients are usually diagnosed with advanced stages where complete cytoreduction and standard platinum-based chemotherapy are the mainstay of treatment. Advances into the molecular underpinnings of DNA damage repair highlighted BRCA 1/2 and other related genes as key regulators of platinum sensitivity. Our study characterizes clinical features and outcomes associated with BRCA mutations in a cohort of ovarian cancer patients.

METHODS
Patient data from our Institute was retrospectively extracted for all patients that were tested for the presence of BRCA germline or somatic mutations through next generation sequencing between May 2016 and August 2018.

RESULTS
Eighty-eight patients were included in the present analysis. Advanced FIGO stage IIIC-IV was common at presentation (71.6%), with 58% of patients undergoing primary debulking surgery. BRCA mutant cases represented 44% and were associated with a significantly higher frequency for complete pathologic response, first and second platinum sensitive relapse and a significantly longer overall survival for advanced stage cases treated with neoadjuvant chemotherapy. Mean age at presentation was significantly lower in the BRCA mutated (52 years) compared to BRCA wildtype patients (54.2 years, p=0.045).

CONCLUSIONS
Upfront knowledge of BRCA status is encouraged, given the recent advent of targeted therapies and for the decision regarding optimal sequence of available therapeutic strategies.


This study deals with the stability characteristics of journal bearings using the finite element method. Two different elements, a 3-node linear triangle and a 6-node quadratic triangle, have been used. The results show a significant difference in (1) stiffness and damping coefficients and (2) stability characteristics at high eccentricity ratios due to the use of the two different elements.


The present invention relates to a method for controlling a fluid system (10) of the working machine (1). The fluid system includes a hydraulic machine (13) for providing the one or more actuators of the work machine the fluid (11, 12). The method, wherein when the first actuator of the one or more actuators (11) has a maximum load pressure among the one or more actuators, based on the load pressure of the first actuator as a condition receiving a signal for requesting the pump pressure from said hydraulic machine (13), that said first actuator is stalled due to overload or geometric limitations, the first and to determine the pressure request from one of the actuator (11), the one or the second actuator of the plurality of actuators (12) is in operation, and it is the one or more actuators when having the maximum load pressure to the second of the, or to control the hydraulic machine (13) so as to provide a pump pressure based on the load pressure of the second actuator or said first actuator, If the actuator running more other does not exist, it involves a to control the hydraulic machine in order to provide a predetermined idle pump pressure, the. .FIELD 2


Research in education and physical education has emphasized the need for continuing professional development (CPD) programs that are aligned with best practices. More specifically, scholars interested in teaching personal and social responsibility (TPSR) have emphasized the need to examine teachers' CPD. The purpose of this study was to provide a novel responsibility-based CPD experience to three physical educators and examine its impact on a middle school physical education program in the USA. Data were collected through systematic observations, interviews, nonparticipant observations and document analysis. Findings showed that the physical educators increased their awareness of responsibility-based teaching strategies, perceived them to positively impact students and integrated the strategies into their teaching. Furthermore, descriptive statistics illustrate frequent use of the teaching strategies and confirms the reliability of the observation instrument. The findings suggest that systematic observations can support responsibility-based CPD for the purposes of research, peer evaluations, or as a reflection tool. The long-term approach enhanced the potential for sustainability.


As one of the most active research fields in neural engineering,brain-computer interface(BCI) has important research significance and great potential applications in many fields including biomedicine,neurological rehabilitation,and intelligent robotics.In the last decade,BCI has made great progress and rapid development,and its application field is also gradually expanding.In this study,based on related work,the main components consisting of the BCI system were detailed,then related basic theories and techniques involved in these components were summarized and described including brain signal acquisition,signal preprocessing,feature extraction,and transformation algorithms.Finally,an overview of the trend of future BCI development was discussed.


Background: Safe and effective treatment of infantile colic (IC) has not yet been determined. In this study, the authors aimed to investigate the efficiency of 30% glucose solution in the treatment of IC.


Any useful clinical test of hearing suggests at least one of the following functions: 1) Diagnosis and prognosis connected with ear disease; 2) evaluation of medical or surgical therapy or a hearing aid; 3) estimation of the social adequacy or disability of hearing. Since the earliest days of otology these have been the three major purposes for hearing tests and they have not all been achieved (equally well) by the different tests that have been developed.


Dear editors, Rare diseases are considered as diseases or conditions of public health concern at European level, and a priority to be included in the context of the European Health Union [1]. The European definition of a rare medical disease or condition is established on the low prevalence, meaning less than five affected persons per 10,000 people (not more than one person per 2000 in the European population [2]. According to Orphanet, a European portal for rare diseases and orphan drugs, currently, there are over 6000 known rare diseases, most of them have a genetic background. Some rare diseases are caused by a combination of genetic and environmental factors. Other rare diseases can be non-genetic - there are rare forms of infectious diseases (bacterial or viral), auto-immune diseases, toxic disorders, and rare cancers. In other cases, the cause of rare diseases is still unknown. At EU level has been established an appropriate public health policy and professional care on rare diseases. European Reference Networks (ERN) are part of this public health policy. ERNs are virtual networks involving healthcare providers across Europe. They aim to tackle complex or rare medical diseases or conditions that require highly specialised treatment and a concentration of knowledge and resources [3]. The fundamental principle of ERNs is share, care, and cure. ERNs use specific telemedicine tools and IT solutions, thus the medical knowledge, best practices, and clinical expertise travel rather than the patient. In the European Union, it is estimated that 30 million people are living with a complex, often chronic, and progressive, rare disease. If we are looking for statistics on rare diseases, it is obviously that individual diseases may be rare, but collectively are common. Moreover, a rare disease may be rare in one region, but common in another. The limited number of patients, widely geographically dispersed affected people, lack of scientific knowledge and medical expertise were barriers in providing quality healthcare services for people with rare diseases. The former European Commissioner for Health, and Food Safety, Vytenis Andriukaitis, considered that "no country alone has knowledge and capacity to treat all rare and complex conditions" [4]. So, in 2017, the European Reference Networks launched to enable the exchange of all the available knowledge and expertise on rare diseases between EU State Members. To date, there are 24 thematic networks working on a wide range of rare non-communicable conditions, such as ERN-BOND on bone disorders, ERN-CRANIO on craniofacial anomalies, EndoERN on endocrine conditions, EuroBloodNet on haematological diseases, ERN LUNG on respiratory diseases, etc. Information about all ERNs on rare diseases are available at: https://ec.europa.eu/ health/european-reference-networks/overview_en. The ERNs were developed by the EU and national governments to facilitate improvements in access to diagnosis, treatment, and provision of affordable, high-quality, and cost-effective healthcare for transforming the lives of all patients [4]. In 2020, it was published a study on the opportunity of setting a European Expert Network on Rare diseases linked to Mobility and Globalisation (EURaDMoG). The study funded by the EU aimed to improve healthcare provision with regards to "imported diseases" brought by a mobile population coming from tropical countries [5]. The list of rare communicable diseases linked to mobility and globalisation identified throughout the EURaDMoG study is available at https://op.europa. eu/en/publication-detail/-/publication/0606dc45-5c 3b-11ea-8b81-01aa75ed71a1/language-en (Annex 1, page 54) [5]. Imported diseases are not familiar to European health professionals. Population movements, such as global mobility related to tourism or trade, labour migration, family reunification, and refugees, are linked to the spread and control of communicable diseases. The field has recently been recognized as a new challenge as the rare communicable diseases have been found to be prevalent only in mobile populations coming from tropical countries [6]. Thus, Lindenmeyer et al., 2016, noted the need for additional work to improve the knowledge gap among different categories of health care providers [7]. EURaDMog study made a thorough and context-specific assessment on how successfully would be a European expert Network on rare diseases liked to mobility and globalization. The study considered different scenarios, conducted a comprehensive literature review in the field, organised a consultation workshop, and made an overall 364 feasibility assessment. It is important to acknowledge, that the study compared how diagnosis and treatment of rare diseases, both non-communicable and communicable, are covered by existing ERNs. The results of the study indicated that more than 130 infections were identified. They were considered rare conditions in the EU28 and EEA (European Economic Area) countries and were linked to mobility and globalisation. The study revealed that these rare conditions have no appropriate or widely available diagnostic techniques and treatments [5]. Moreover, rare non-communicable diseases linked to mobility and globalisation are covered by 24 different thematic networks. Focussing on rare communicable conditions, the study analysed the current European Network dealing with such conditions. In Europe, most of expert networks focussing on tropical medicine, travel medicine or parasitology organisations are mainly involved in research and training activities and do not provide health care services. Other networks with some focus on health care provision and patient care essentially improved through exchange of information, continuous education, and training of health professionals such as TROPNET (European Network for Tropical Medicine and Travel Health), EuroTravNet (European Travel and Tropical network of the International Society of travel Medicine), and EVDLabNet (European expert laboratory network for emerging viral diseases) do not cover all rare communicable diseases, are functioning with low resources, and most of them are private [8]. Additionally, most of them are not recognised by national health care systems. The study assessed the establishment of the network, thematic area to be covered, data registry, improving the health care provision, governance, coordination and management of the network, patient care, continuous education, training and development, research activities, multidisciplinary approach, networking and collaboration, funding sources and sustainability. This study concluded that, in EU and EEA, rare communicable diseases in the new context of mobility and globalisation are not sufficiently covered by existing expert networks. The new potential network should be complementary to the current existing networks. In no circumstances, it is not seen as a duplication of current network. The ERN can bring real added value to improve the health care provision of rare communicable diseases [5]. Recommendations of the study should be discussed with Member States policymakers.


Wang Guowei, in his "Postscript to Bei Bo Ding", identifies the state of Bei with the state of Yan, the early Chou state founded by Duke of Shao. While supplying us with a new vision of the early history of the states of Yan and Bei, Wang's theory offers no explanation as to why the state of Yan would also be named Bei, and how Wu Geng, the crown heir of Di Xin, the last king of Shang, would have been related to Yan. Chen Mengjia locates the State of Bei at a place north of Zhaoge but within the former domain of the Yin. He also postulates that the state of Bei was moved to Yan, in modern Hebei, after the Duke of Zhou and King Cheng's suppression of the rebellion led by Wu Geng. This paper reviews the literature and various sources regarding the State of Bei and the founding of the State of Yan since Wang Guowei published his celebrated paper. While partly agreeing with Chen Mengjia's opinion that the state of Bei moved to the location of Yan, this paper shows that the first place where Wu Geng took refuge after his defeat in the rebellion was not modern Hebei, but modem Shandong. He fled to the north after his second failure, in the rebellion of Eastern States of the Shang. From reading bronze inscriptions and consulting historical records, one sees that the rebellion of Wu Geng was not put down until fairly late. Yan was a place both of origin and of refuge for the Shang people. Duke of Shao adopted the place name Yan for his state partly for the sake of pacifying the Shang loyalists.


Latent diffusers revolutionized the generative AI and inspired creative art. When denoising the latent, the predicted original image at each step collectively animates the formation. However, the animation is limited by the denoising nature of the diffuser, and only renders a sharpening process. This work presents Latent Painter, which uses the latent as the canvas, and the diffuser predictions as the plan, to generate painting animation. Latent Painter also transits one generated image to another, which can happen between images from two different sets of checkpoints.


The stability properties of rotating relativistic stars against prompt gravitational collapse to a black hole are rather well understood for uniformly rotating models. This is not the case for differentially rotating neutron stars, which are expected to be produced in catastrophic events such as the merger of binary system of neutron stars or the collapse of a massive stellar core. We consider sequences of differentially rotating equilibrium models using the $j$-constant law and by combining them with their dynamical evolution, we show that a sufficient stability criterion for differentially rotating neutron stars exists similar to the one of their uniformly rotating counterparts. Namely: along a sequence of constant angular momentum, a dynamical instability sets in for central rest-mass densities slightly below the one of the equilibrium solution at the turning point. In addition, following Breu & Rezzolla (2016), we show that "quasi-universal" relations can be found when calculating the turning-point mass. In turn, this allows us to compute the maximum mass allowed by differential rotation, $M_{\rm
max,dr}$, in terms of the maximum mass of the nonrotating configuration, $M_{_{\rm TOV}}$, finding that $M_{\rm max, dr} \simeq \left(1.54 \pm 0.05\right) M_{_{\rm TOV}}$ for all the equations of state we have considered.


Acknowledgements Soundtrack Figures 1. Theoretical Introduction to Sound Media Part I: The Present Time 2. The Acoustic Computer. Nervous experiments with Sound Media 3. Synthetic Music. Digital Recording in Great Detail 4. The Mobile Public. Journalism for Urban Navigators 5. Phone Radio. Personality Journalism in Voice Alone 6. Loudspeaker Living. Pop Music is Everywhere Part II: Backwards History 7. Tape Control. A Revolution in Music Recording 1970s - 1950s 8. The Acoustic Nation. Live Journalism 1960s - 1930s 9. Microphone Moods. Music Recording 1940s - 1930s 10. The Live Public. Experiments in Broadcasting 1920s - 1900s 11. The Repeating Machine. Music Recording 1920s - 1870s. Literature. Soundtrack Supplement. Index


Source code repositories managed by the popular CVS are frequently mined by researchers to validate various hypotheses about how the development of a software product progressed. This paper presents a study where the development process of 17 student teams was followed. It will show that in an environment where the teams were permitted to manage their own CVS repositories that several errors emerged that could lead to the misinterpretation of a hypothesis. These were classified into three types: type one errors which relate to the non-use of the system; type two errors that emerged from the direct manipulation of the repository; and type three errors from the limitation of CVS not to record file name changes.


On 4 July 1950 North Korean People's Army came in Incheon. But the mayor of Incheon city escaped on June 28 when the army didn't yet enter into Incheon, and civil servants, military and police of Incheon also pulled out. By the way, on June 29 the military and police came back by guidance of right-wing youth organization and raided and killed more than 700 'civilians' who was ready to welcome North Korean People's Army at the Incheon City Hall. Many of dead were Members of Federation Protecting and Guiding the Public of Incheon and their family. After occupation of Incheon, North Korean People's Army received major agencies and reformed the organizations. Occupation force brought more than half of people needed to rule occupied area over from North Korea. More than half of 99 members in police of Incheon were from North Korea and most of them were the Korean Workers' Party members, who controled center of police and served as chiefs of affiliated organizations. Most of local people chosen and appointed were from poor peasant and labor and helped their seniors from North Korea carry out missions to cooperate with the occupation rule and wartime mobilization. Massacre happened on the verge of occupation made it difficult for occupation force to obtain local assistants. Meanwhile, North Korean People's Army paid attention to the fact that the hundreds of leftists and citizens were killed just before their capture and actively took advantage of the fact for their occupation rule. The funeral home for victims of the Federation Protecting and Guiding the Public reminded of the place to enlist volunteer army. Also propaganda and incitement reminding of sacrifices became a driving force to sustain their occupation rule. Because of the tragedy right before North Korean people's army's occupation and early escape of civil servants, while government authority before war lost popularity, North Korean people's army seemed to control fully the community of Incheon. However continued bombing from the air and naval bombardment from the sea by the US army destroyed the daily lives of citizens and made fully captured rule impossible. Massacre of leftist weakened the base of their occupation rule, too. At last, sharply amid fears about large-scale landing of UN army, North Korean people's army began to prepare the punishment of right-wing political prisoners which had been restraint before retreating.


Hyperparathyroidism associated with long‐term lithium therapy is well described. However, few studies have clearly defined the pathological findings or looked at the outcome of surgical treatment.


Background: "We reveal from the Quran that which is healing and a mercy for the believers" Holly Quran (surah al Israa 17:82). Quran therapy has been shown to modulate the stress response in different life situations. This study designed to determine the effects of Quran therapy on intraoperative sedative requirements and whether it can achieve similar degree of sedation by monitoring Hemodynamic parameters in patients undergoing lower limb surgery under spinal anesthesia. Methods: In this study 50 cases of ASA Grade I and II between 20-60 years of age from both sexes, undergoing lower extremity surgery under spinal anesthesia, were randomized into Group Q (those who listened to Quran) and Group M (those who didn't listen to Quran and took midazolam as a sedative). After the induction of spinal anesthesia, and achieving the desired effects and levels of spinal block, headphones were applied to all the patients and Quran was started in group Q. The intraoperative vital parameters and total sedative requirements were recorded and compared in both the groups. Results: The total midazolam requirements were significantly lower in patients who listened to Quran intraoperatively (2.17 ± 0.53 mg versus 3.25 ± 0.77 mg; P=0.02), for achieving similar degree of sedation (Ramsay grade 3). The mean pulse rate was significantly lower in group Q as compared to group M (from 68-76 versus 86-98; P<0.05) at 30-120 minutes intervals intraoperatively. Systolic and diastolic blood pressure were comparable in both the groups, with insignificant difference at all times (P>0.05), though the patients in group Q reported a higher sense of satisfaction and wellbeing postoperatively. Conclusions: Our findings suggest an important role of Quran in per anesthetic patient care. We conclude that Quran is a non-pharmacological alternative which is suitable for decreasing intraoperative sedative requirements in patients under spinal anesthesia. Introduction Regional anesthesia is popular and offers several benefits to the patient such as staying awake, early family contact, and early food intake. For the anesthetist, cardiovascular and respiratory stability, rapid postoperative recovery, and preservation of protective airway reflexes are the most important advantages of regional anesthesia. Surgical procedures performed using regional anesthesia techniques present a special challenge to anesthesiologists because patients are awake and exposed to multiple anxiety provoking visual and auditory stimuli [1]. Therefore, sedative and anxiolytic drugs are regularly administered before and during surgery, for the purpose of calming patients, but at the cost of dose dependent central nervous system and cardio-respiratory system depression [2,3]. Different drugs have been tried in the past to achieve sedation, the most prominent among them being diazepam, propofol, midazolam and ketamine. Non-pharmacological alternatives like acupressure, hypnosis, therapeutic suggestions and music have also been tried in the past, with varying results, to avoid the complications from the overdose of the sedative drugs [4]. Auditory input is a known modulator of the human response to stress [5]. Listening to Quran recitation was selected as a non-pharmacological intervention to reduce stress [6]. There was no previous studies have compared the efficacy of intra-operative Quran therapy in decreasing sedative or analgesic requirements .This study aimed to observe the role of Quran therapy in the modulation of Hemodynamic variables such as heart rate and mean blood pressure and on the intraoperative requirement of sedatives for achieving similar degrees of sedation.


Objective:To detect the engraftment capability and hematopoietic potential of the expanded cells,establish an optimized project of ex vivo expansion and the SCID mice model of UCB transplantation.Methods:Human cord blood CD34 + cells were clutured in strom free liquid culture system,the sublethally irradiated SCID mice were injected with human expanded cord blood cells by tail vein.Four weeks after inocuration,BM cells of the survived animals are obtained from both femurs and tibias and assessed for the presence of human cells by immunofluorescence staining and PCR.Results:The cells and CFUs of group FL+TPO+SCF+IL 6 were increased significantly,and maintained some proportional CD34 + cells.The CFU of group SCF+IL 6+IL 3+GM CSF+EPO had reduced in week 2,CFC and CD34 + cells and Alu gene were detected in SCID mice BM.Conclusion:The cytokine combination with FL+TPO+SCF+IL 6 can effectively expand UCB CD34 + cells,and the expanded cells can engraft the BM of sublethally irradiated SCID mice and reconstitute hematopoiesis.


In the face of the swift development of network econ om y, it is most attentive for every professional to learn that how their organizat ions develop, especially after entering the WTO. Based on the necessitation of o ur organizations' multifarious development, the paper analyzes the collective pr oblems which these organizations should confront at present, and prospects the t rend of their developmental in the future and proposes the developing means.


Publisher Summary This chapter focuses on the fracture and yielding behavior of food gels. The fracture and yielding behavior of food gels is an important mark of quality, affecting aspects, such as (i) eating quality; (ii) usage properties, for example, ease of cutting and spreading; (iii) handling properties during storage and/or further processing in connection with, for example, shape retention and pumping characteristics. These aspects pertain to the fracture and yielding behavior of gels under widely varying conditions and time-scales. During eating, for example, a gel is quickly deformed until it fractures; the time-scale of this deformation is less than a second. On the other hand, the time-scale of shape retention during storage may be of the order of days or (much) longer. Fracture and yielding are properties that are concerned with large deformations. However, most of the fundamental rheological studies have been done at small deformations. Often, there is no direct relation between them. General characteristics of a macroscopic fracture are: (1) simultaneous breaking of bonds between the structural elements forming the network (for example, atoms, molecules, crystals) in a certain macroscopic plane; (2) breakdown of the structure of the material over length-scales clearly larger than the structural elements, resulting in the formation of cracks; and (3) ultimately, the falling apart of the material into pieces. The first characteristic also applies to viscous flow. Yielding does not include the third characteristic of macroscopic fracture; it results in a material that flows.


Near-bottom copepod aggregations were investigated in Shijiki Bay by means of stomach content analysis of juvenile red sea bream, near-bottom towing of plankton nets and direct under-water observation with the aid of scuba-equipment. The stomach contents of 220 red sea bream juveniles, 12.7 to 43.7mm in FL, were examined. Nearly 80% of the total food items consisted of copepods, 97% of which were pelagic species. The overwhelming majority of them were Acartia omorii and A. steueri. The near-bottom towing of plankton nets revealed a landward increase in the abundance of pelagic copepods. Two types of near-bottom aggregations were recognized by scuba-diving; a flat carpet-like type with thickness of about 30cm, and a discrete ball-like swarming type with a long axis of about 50cm. The former appeared to be formed by A. omorii and the latter by A. steueri. The maximum density found was 326 per liter far A. omorii and 511 for A. steueri, these being 100 times greater than the background density. The three approaches used in the present study clearly demonstrated the existence of near-bottom aggregations of Acartia omorii and A. steueri; the former rather widely distributed, whereas the latter is restricted to the innermost area shallower than 15m. These two species each shows a distinct macro- and microdistribution pattern which results in a high degree of habitat segrega-tion.


The article proves the necessity for development of the management system for the laboriousness and cost of the high-tech production in mechanic engineering to improve the efficiency of employment of the costly material and labour resources. The development of the management system should take into account the principle features of researches and developments, the result of which is creation of the high-tech products, and which are systematized by the author.


In this thesis, we will present time-resolved experimental investigations of ultrafast spin phenomena in ferrimagnetic metallic alloys of GdFeCo. Recent studies of such ferrimagnetic systems have revealed that a femtosecond optical excitation is not only able to demagnetize such a system on a subpicosecond timescale, but also to permanently reverse its magnetization without any other external stimulus like a magnetic field. Although several theoretical approaches were made to explain the ultrafast loss or even reversal of the magnetic order, the actual mechanisms behind such spin phenomena still remain unclear. One of the key issues is, e.g., how the spin and orbital angular momentum of the electrons, which gives rise to the magnetic moment, is transferred out of, or into the electronic system on such a short timescale after excitation. Another issue concerns the way a light pulse can interact with the magnetic medium during the excitation process. In general, this can either be a thermal mechanism relying on ultrafast light-induced heating of the electronic system or a non-thermal, opto-magnetic mechanism like the Inverse Faraday Effect (IFE) generating a helicity-dependent induced magnetization or an effective opto-magnetic field pulse upon excitation with circularly polarized light. However, the actual role of the latter non-thermal mechanisms on a femtosecond timescale in highly absorbing materials like metals, where thermal effects usually dominate, is highly debated. The scope of this thesis is to shed light upon both of the aforementioned issues. To reveal the path of angular momentum flow during ultrafast laser-induced demagnetization of a ferrimagnetic GdFeCo alloy, we employ timeand element-resolved soft x-ray magnetic circular dichroism (XMCD) measurements at the FemtoSpeX fs-slicing facility of the BESSY II synchrotron light source. A magneto-optical sum rules analysis of the fs-XMCD data allows us to disentangle and monitor the dynamics of both spin and orbital moments individually, at Fe and Gd sites. Our experimental data enable us to conclude on a full transfer of angular momentum from both spin and orbital moments of Fe and Gd to the atomic lattice during the first hundreds of femtoseconds after excitation. Within our experimental time resolution of ≈ 130 fs, there is also no indication for an interatomic exchange of angular momentum between Fe and Gd, as well as for an accumulation in the orbital moment. Thus, the latter can be ruled out as a bottleneck for the angular momentum transfer to the lattice. In order to reveal the influence of a non-thermal, opto-magnetic mechanism like the IFE in metallic ferrimagnets like GdFeCo, we use a novel approach of inducing helicity-


To the Editor:

In their recent article, Vemmos et al reported the impact of body weight on short-term and long-term outcome after stroke.1 They observed that overweight and obesity were associated with lower, not higher, mortality as compared with normal body mass index (BMI). Although these results run counter to common knowledge on obesity as an adverse factor in primary disease prevention, they are fully in line with an increasing body of evidence of an inverse (or paradox) association in subjects with established chronic or acute diseases.

The authors themselves, however, seem hesitant to rely on their results for clinical application. They conclude, that "the results cannot support recommendations to patients not to loose weight." Disentangling this double negation leaves us with an encoded statement that current recommendations on weight management should be pursued regardless …


ABSTRACT The changes of growth characteristics and antioxidant activity for selection of optimum germinated temperature on common bean ( Phaseolus vulgaris L.). Common beans (IT100888, IT102849, and IT231267) were cultivated at 20℃, 23℃ and 25℃ during 5 days of germination. The range of whole length, hypocotyls length, thickness, abnormal germination and yield rate of sprouts was 7.27~27.62 cm, 3.10~18.86 cm, 1.80~2.27 mm, 5.54~18.34% and 205.95~ 618.71%, respectively. Antioxidant activities of common beans with germination temperature investigated. Common beans (IT100888, IT102849, and IT231267) germinated at 20℃, 23℃ and 25℃ during 5 days, and then extracted with 80% ethanol, and analyzed for total polyphenol content, DPPH and ABTS radical scavenging activity. Total polyphenol content increased from 474 mg GA eq/100 g sample for IT231267 to 1364 mg GA eq/g sample for 23℃ of germination. DPPH radical scavenging activity of IT102849 increased from 189mg Trolox eq./100 g sample (20℃) to 1073mg Trolox eq./100 g sample (23℃) also ABTS radical scavenging activity of IT234267 increased from 479 mg Trolox eq./100 g sample (20℃) to 1134 mg AA eq/100 g (23℃). These results suggest that germination temperature for increasing antioxidant activities may be 23℃.


In the extension of Maxwell equations based on the Aharonov–Bohm Lagrangian, the e.m. field has an additional degree of freedom, namely, a scalar field generated by charge and currents that are not locally conserved. We analyze the propagation of this scalar field through two different media (a pure dielectric and an ohmic conductor) and study its property over a frequency range where the properties of the media are frequency-independent. We find that an electromagnetic (e.m.) scalar wave cannot propagate in a material medium. If a scalar wave in vacuum impinges on a material medium it is reflected, at most exciting in the medium a pure "potential" wave (which we also call a "gauge" wave) propagating at c, the speed of light in vacuum, with a vector potential whose Fourier amplitude is related to that of the scalar potential by ωA0=kϕ0, where ω2=c2k2.


Announcing dreams are pregnancy dreams about the child a woman is carrying. They may be had by expectant fathers and other persons close to the mothers, and they may occur before conception and after birth as well as during pregnancy. Related to announcing dreams are a variety of other extraordinary experiences, such as visions, apparitions, and messages passed through mediums. When they occur in reincarnation cases, these experiences allow parents to infer the past-life identities of their unborn children. Critics interpret announcing dreams and related experiences as psychological projections by the dreamer, rather than communications from unborn children. Regardless of how they are understood, the announcements help parents prepare for the unexpected and can lead to life-changing decisions.


ABSTRACT Background: Neuropsychiatric symptoms (NPS), such as depression, apathy, agitation, and psychotic symptoms are common in mild cognitive impairment (MCI) and dementia in Alzheimer's disease (AD). Subgroups of NPS have been reported. Yet the relationship of NPS and their subgroups to different stages of cognitive impairment is unclear. Most previous studies are based on small sample sizes and show conflicting results. We sought to examine the frequency of NPS and their subgroups in MCI and different stages of dementia in AD. Methods: This was a cross-sectional study using data from a Norwegian national registry of memory clinics. From a total sample of 4,571 patients, we included those with MCI or AD (MCI 817, mild AD 883, moderate–severe AD 441). To compare variables across groups ANOVA or χ 2-test was applied. We used factor analysis of Neuropsychiatric Inventory Questionnaire (NPI-Q) items to identify subgroups of NPS. Results: The frequency of any NPS was 87.2% (AD 91.2%, MCI 79.5%; p < 0.001) and increased with increasing severity of cognitive decline. The most frequent NPS in MCI was depression. Apathy was the most frequent NPS in AD across different stages of severity. The factor analysis identified three subgroups in MCI and mild AD, and a fourth one in moderate–severe AD. We labelled the subgroups "depression," "agitation," "psychosis," and "elation." Conclusions: The frequency of NPS is high in MCI and AD and increases with the severity of cognitive decline. The subgroups of NPS were relatively consistent from MCI to moderate-severe AD. The subgroup elation appeared only in moderate-severe AD.


In the background of empirical school and critical school's occupying a dominant position in communication research,empirical method and deductive method are the two traditional methods of communication research.But as a basic philosophic method,phenomenological method has not been paid enough attention in communication research all along,even though it has been widely used in social science and natural science.On the foundation of introducing seeing of an essence,the author considers that in a sense,phenomenological method transcends empirical method and deductive method,especially contributes to solve the problem of the relationship between individuality and generality,phenomenon and essence,so it should be paid enough attention and used in communication research.


Based on field survey and data collection,the main ornamental fruit tree species and configuration forms in different green space types of Nanjing were summarized and analyzed in the paper.The results showed that: Nanjing urban landscape ornamental fruit trees were mainly in 27 families,a total of 86 species,and 2 varieties.The largest Division was the rose family,accounting for 31.8%;It was followed by fagaceae,walnut and persimmon families,the 4 types accounted for 50% of the total;the application forms were tree-lined class,hedge class,twining climbing,and pot types;it summarized the ornamental fruit trees types with the wild popularization value and good greening effects in Nanjing urban green space;and it put forward reasonable development and utilization suggestions.


The 'Logico-Philosophicus Serial Booklet' (abbrev as LPSB hereafter) consists of three interrelated academic works in Philosophy research. The research areas and fields covered by those works include Philosophy of Language, Philosophy of Phenomenology and Study of Classic Axioms in Science. This short article provides a brief overview on the constitutional structure and the development purpose of LPSB. At the end of it, we provide basic information on the author of LPSB, the time points related with the paper-writing efforts, the duration of the whole development and the web links of those three works of LPSB. In the appendix, we include the abstract of them and the prologue to 'On Axioms'.


Antony Barbieri-Low presents an engaging and well researched analysis of the changing image of the First Emperor of Qin throughout centuries. Yet the study suffers from insufficient attention to nuances of Chinese political culture, from outright dismission of looted manuscripts (some of which are essential for understanding the Qin), and, primarily, from the author's own biases. Do these biases suggest the author's desire to use the First Emperor as a foil in U .S . political debates?


The concept of multiresolution analysis is applied to analyze the interference of scales in the reduction of the degrees of freedom for nonlinear partial differential equations. The selection of the relevant degrees of freedom is performed within a rigorous and systematic construction of projection operators in the context of renormalization group theory and homogenization. Using the representation of operators in a basis of compactly supported wavelets, we explicitly calculate the contributions from each scale for every order in the reduction of the degrees of freedom. Contrarily to representations of the projection operators in real space and Fourier space, we show that the selection of the relevant degrees of freedom follows a certain pattern in the off-diagonal elements in the wavelet representation. Finally, the wavelet representation allows us to identify each relevant degree of freedom for the Burgers nonlinearity within each scale explicitly.


Objective
To investigate the role of cyclooxygenase-2 (COX-2) in podocyte injury in diabetic rats mediated by the disruption of low-density lipoprotein receptor (LDLr) pathway.

Methods
Eight-week old male Sprague-Dawley (SD) rats were treated for 12 weeks by dividing into three groups: control rats, streptozotocin (STZ) induced diabetic rats (DM), and diabetic rats treated with aspirin (DM+ Aspirin). The plasma lipid profile was checked by clinical biochemistry assay. The ratio of urinary microalbumin to creatinine (ACR) was detected by enzyme-linked immunosorbent assay. Intracellular lipid accumulation was evaluated by Oil Red O staining and a free cholesterol quantitative assay. The glomerular podocyte injury and the expression of molecules related with LDLr pathway were evaluated by electron microscope, immunohistochemical staining, immunofluorescent staining, and Western blotting.

Results
There were increased levels of urinary ACR (P <0.01) and podocyte injury(P <0.01) in DM rats compared with the controls. Additionally, lipid accumulation in kidneys of DM rats were significantly increased (P <0.01), due to increased protein expressions of COX-2, LDLr, sterol regulatory element-binding protein (SREBP) cleavage activating protein (SCAP), and SREBP-2 (P <0.01). However, these changes were significantly inhibited by an inhibitor of COX-2, Aspirin (P <0.05). It's worth noting that, COX-2 protein expression was closely correlated with LDLr protein expression (r=0.85, P <0.01).

Conclusion
Dysregulation of LDLr pathway contributes to podocyte injury in diabetic nephropathy, which may be mediated through the increased COX-2 expression.

Key words:
Cyclooxygenase 2; Receptors, LDL; Diabetic nephropathies; Podocytes


Energy efficient routing in sensor networks has been of great interest in the research community. Cluster-based data collection using aggregation and routing is an effective way of improving energy efficiency in sensor networks. However most cluster-based routing protocols assume a CH-to-CH form of multi hop communications. This assumption may not be valid in typical application scenarios due to battery power and transmission range constraints, hence requiring some sort of gateway mechanisms between cluster heads. Incorporating and modifying the underlying concept of flooding in a clustered network implemented in CBRP, we propose a selective flooding-based routing protocol (SFRP) for multi hop routing; SFRP is specifically targeted at environmental monitoring applications, where sensor nodes typically form a spanning-tree structure rooted at a single sink node. Simulations show that the protocol has reduced control overhead thereby saving energy in the route formation phase.


Throughout college life, the wealth of academic obligations creates a burden on the student representative, which in turn causes stress and unnecessary anxieties. USFQstudio aims to better organize student responsibilities to thereby eliminate unnecessary stress, to better allocate time towards specific asks and to provide a better quality of study throughout student life. We worked with 80 students between the ages of 18 and 22 at the Universidad San Francisco de Quito. Surveys were conducted to evaluate the problem and qualitative research focused on a user-centered design was developed. Prototype testing began as low-level and was improved with user feedback. For the final evaluation, before and after interviews were conducted to test the prototype. The students confirmed their satisfaction with using the platform and expressed their desire to start using the application as it generated a sense of security, demonstrating a reduction in stress levels and thus improving the quality of student life.


Although the process of the old and new sulfuric acid production system is the same,but the cleaning,drying and absorbing,and the conversion section of each system vary in some degree.This article mainly introduces the differences and properties of the two systems.


Citation: Ripamonti C, Aboshiha J, Henning GB, et al. Vision in observers with enhanced S-cone syndrome: an excess of S-cones but connected mainly to conventional S-cone pathways. Invest Ophthalmol Vis Sci. 2014;55:963–976. DOI:10.1167/iovs. 13-12897 PURPOSE. The effect of increased numbers of S-cone photoreceptors in enhanced S-cone syndrome (ESCS) was investigated psychophysically in six ESCS observers to understand more about relative cone sensitivities and postreceptoral organization.


Backward erosion piping is an internal erosion mechanism during which shallow pipes are formed in the direction opposite to the flow underneath water-retaining structures as a result of the gradual removal of sandy material by the action of water. It is an important failure mechanism in both dikes and dams where sandy layers are covered by a cohesive layer. Sand boils can indicate that backward erosion is present and they are observed regularly during high water and floods. Although failure resulting from backward erosion piping is not common, several dike failures in the US, China and the Netherlands have been attributed to this mechanism. Given the impact that climate change is expected to have, prediction models for backward erosion piping are becoming increasingly important in flood-risk assessment. The prediction models available until now, such as Bligh's rule and the Sellmeijer model, were validated in the research programme 'Strength and loads on flood defence structures' (SBW: Sterkte en Belastingen Waterkeringen) in the period 2008-2010 using small-, medium- and large-scale experiments. These experiments showed that an empirical adjustment of the Sellmeijer model was required to take the effect of the sand type into account and that validation was not possible for loose sand types because the erosion mode is different in those conditions. However, the absence of a theoretical basis makes this proposed empirical adjustment unsatisfactory because it lacks robustness. The main question addressed by this dissertation is how to explain and predict the pipe-forming erosion processes in uniform sands. A review of the literature, in conjunction with additional experiments, showed that the critical head in pipe formation leading to dike failure depends on either pipe initiation or pipe progression. In some experiments, the critical head for pipe initiation exceeds that of pipe progression and equilibrium is therefore prevented. The experiments in which no equilibrium was observed allowed for the development of a model for pipe initiation. It was possible to relate the observed differences in critical gradient caused by scale, sand type and configuration to the fluidisation of sand very close to the exit, where the local gradients are high. In the field, pipe progression is likely to determine the critical gradient. The Sellmeijer model predicts the progression of the pipe on the basis of the equilibrium of particles on the bottom of the pipe. The literature, and an analysis of the pipe width, depth, gradient and erosion process in experiments, indicate that pipe progression relies on two processes: primary erosion, which causes the removal of particles at the pipe tip, and secondary erosion, which causes the erosion of the pipe walls and bottom. Although the Sellmeijer model does not include primary erosion, it does function well for sand layers with a 2D exit configuration in which there is no variation in the grain size along the pipe path. The adaptation of the Sellmeijer model that was found necessary to account for the effect of sand type can be replaced by using the original model in combination with a variable bedding angle based on incipient motion experiments from the literature. The Sellmeijer model does not predict the critical gradient well for 3D configurations such as flow towards a single point, or for heterogeneous soils. Variations in the grain size in the pipe path were found to result in significantly higher critical gradients than expected, whereas a strong concentration of the flow towards the exit led to a fall in the critical gradient. 3D numerical calculations and the inclusion of primary erosion in the Sellmeijer model are needed to predict piping under these conditions.


An attempt has been made to study the thermal properties of soil at five different sites, namely, Khanda, Derol, Sanand, Amej and Anand under land surface processes (LSP) experiment in the Sabarmati river basin, Gujarat, utiIising the data collected during 13-17 Feb.1997. Among these sites Khanda and Arnej are of clay soil type, Derol and Anand with soil of loamy sand and Sanand is of clay loam type of soil. For all these sites thermal diffusivity has been calculated by three methods, namely, amplitude decay of diurnal wave (range method); time lag data (lag method) and damping depth concept. The values obtained by all these methods are in good agreement. Thermal diffusivity for clay soil is found to be of lesser values (0.287xl000{; m2 S-I for Khanda and 0.304xWoo{; m2 S-I for Arnej) and for loamy sand and clay loam types it shows higher values (0.677x JOoo{; m2 S-I at Derol, 0.591x woo{;m2 S-I at Sanand and 0.508x 1000{; m S-I at Anand). Diurnal variation of soil temperature at each depth and soil heat flux (surface) are presented. Thermal conductivity has been calculated for all the sites. An attempt has also been made to predict soil temperature profile with time from the theoretical behaviour of thermal wave. Ground heat flux calculated by observed and theoretical profiles of temperature are also presented.


CARVALHO, Humberto Henrique de. Evaluation of molecular particularitities of the "Folha Murcha Me" and others Citrus sinensis (L.) Osbeck and development of SCAR Marker. 2008. 76 p. Dissertation (Master in Plant Physiology) – Federal University of Lavras, Lavras, Minas Gerais Brazil. Amongst Citrus sinensis (L.) Osbeck, 'Folha Murcha Me' presents fruits of excellent quality, rolled up leaves and maturation in the period between harvests, with strong demand for oranges. It is also useful for juice extraction and may be used in the diversification for industrial purposes. Thus, it is very important to know the origin of such variety. Molecular markers RAPD are widely used in studies of molecular biology and as tools in the analysis of genetic diversity. In this context, this work was carried out to study the genetic diversity of the orange trees through RAPD markers and, at the same time, to identify amplified regions of DNA capable of differentiating the orange trees, sequencing these regions and using them for constructing SCAR markers. Percentages of dissimilarities were gotten by means of NTSYS software. The number of polymorphic bands with 17 RAPD primers was efficient for analysis of the data, generating the mark of 28 polymorphic fragments, presenting correlation of high magnitude (r = 0.99). With this number of fragments, the sum of the deviation squares in relation to the samplings and the value of stress were smaller than 0.05 (0.0431), suggesting high consistency in the association of the matrices of dissimilarities. The analysis of grouping, carried out with UPGMA method, produced a dendrogram. The formation of two groups is suggested, one of them consisting of orange trees 'Folha Murcha Me', 'Valencia Tardia', 'Natal', 'Pera Rio', 'Baia ME' and 'Baia'. The genotypes ` Folha Murcha Me' and the normal leaf mutants are 100% similar. Another group would be formed by the oranges `Seleta 1 and 2 and by `Seleta x Cravo'. One polymorphic fragment was transformed into SCAR. The constructed SCAR marker was efficient, given no amplification in the individuals 'Folha Murcha Me' and mutants of 'Folha Murcha Me' and given amplify sequence in the individuals, 'Valencia Tardia', 'Natal', 'Pera Rio', 'Baia ME', 'Baia', 'Seleta' 1 e 2 and for 'Seleta x Cravo'. Therefore, it can be used for identifying orange trees. Guidance Committee: Dr. Luciano Vilela Paiva UFLA (Adviser)


During May 2001, signals were transmitted from five moored 16‐ to 100‐Hz‐bandwidth sources to colocated horizontal and vertical receiving arrays in 120‐m‐depth water on the continental slope. The site was in the northern portion of the South China Sea. Transmissions were nominally 20 km cross slope to the receiver from a site with three closely spaced sources, and 32 km up‐slope to the receiver from a site with two sources, although the bathymetry was complex. Signal frequencies ranged from 210 to 550 Hz. A broad spectrum of water column variations was observed during the 17‐day acoustic experiment with our array of moorings at 20 sites, including the source and receiver locations. Internal tides were consistently present, as were nonlinear internal waves of moderate amplitude. Nonlinear internal waves of larger amplitude propagating from the eastern South China Sea were present only episodically. Subtidal frequency water‐mass variations also occur. Correlation between various measures of the acoustic sig...


In this work, a strategic deep trenching with theoretical optimization is adopted to reach a successful reflective effect of WTC structure. The experimental results are within the reasonable range. We select the SOS refractive index difference of 0.75%, waveguide core size of 5.5 μm × 5.5 μm. We know, only the trench bottom is at the same depth as the waveguide core, the side-wall can reflect the guided-mode from an input waveguide to an output waveguide, so set the trenching depth of 26 μm, which is realized with the inductively coupled plasma (ICP) dry etching technique. Such a deep trenching process has to face the critic challenge in the bottom position and angle of trench side-wall as well as the roughness. At 1.55 μm wavelength, we have experimentally observed the output guided-mode and then measure the average optical loss of each WTC structure is 11 dB, implying that an optical reflective efficiency of 8% has been reached.


Reachable set estimations and non-local optimality conditions for nonlinear control dynamic systems with trajectories of bounded variation and impulsive control of type of a vector measure with a value into a convex cone will be presented; the results are based on applying of sets of strong monotone Lyapunov type functions that satisfy Hamilton-Jacobi quasivariational inequalities modified for the considering kind of problems.


(a) those who are ashamed of their abnormal behaviour; and (b) those who have adjusted themselves.to it and have completely rationalized their feelings towards it. The first group can frequently be approached from the psychiatric angle, whereas the latter group are apparently unassailable. The purpose of this short article is not primarily to discuss the methods for dealing with homosexuality in any given community, but rather to bring it to general notice as an increasingly prevailing practice which presents new problems, and is assuming an alarming importance in the dissemination of venereal disease.


Cellular Ca~(2+) homestasis has been maintained by endoplasmic reticulum(ER).Many activities of Ca~(2+) has been associated with ER.The changes of intracellular [Ca~(2+)] could induce ER stress and overstress has an determined end of apoptosis.Because of the closeness of their position,Ca~(2+) released by ER could induce apoptosis through mitochondrial pathway.Some ER related factors also have attended in the endoplasmic reticulum-induced cellular apoptosis.


Regulatory capture can generate significant social and economic costs, particularly
in dangerous occupations. In this article I evaluate whether political influence has
allowed firms to systematically evade safety and health regulations using data from one
of the country's most dangerous occupations—mining. Using an instrument to capture
exogenous variation in political influence decisions, I show that when mining firms use
influence, they reduce their expected non-compliance costs by 30 percent, but report a
40 percent increase in death rates. Importantly, the largest benefit comes during the
adjudicative stage meant to be isolated from political influence.


Aims: Epidemiological studies of patients with major trauma, including both hospitalized and immediately deceased whom are undergoing medico-legal autopsy, are very rare. We studied the incidence and mortality of major trauma in all 10 districts in the Scandinavian city of Malmö, Sweden, and the association between socio-economic status and major trauma. Methods: Major trauma was defined as a New Injury Severity Score > 15, or a lethal outcome due to trauma. Cases with a registration address in Malmö between 1 January 2011 and 31 December 2013 were identified from the red trauma alarm list in the hospital and the autopsy register in the Forensic Department. Statistics Sweden matched each case with four randomly selected age-, gender- and district-matched controls. Social assistance within the household, level of education, income and capital income were compared. Results: We identified 117 cases (80 men and 37 women) with a median age of 48.0 years (IQR 28.5–65.0). The incidence of major trauma in Malmö was 12.7 (95% CI 10.4–15.0) per 100,000 person-years; and 69 died due to major trauma, with 8.4 (95% CI 6.4–10.4) per 1000 deaths. Lower income (p = 0.024), no income (OR 1.6; 95% CI 1.0–2.4; p = 0.037) and social assistance (OR 2.3; 95% CI 1.3–4.1; p = 0.003) were associated with major trauma. The level of education was not found to be related to major trauma (p = 0.47). Conclusions: Low income and social assistance within the household were associated with major trauma in the city of Malmö, but not the level of education; in this age-, gender- and district-matched case-control study of major trauma.


The present work is devoted to the numerical investigation of the interaction between thermal and solutal convection in enclosures used for modeling directional solidification. The full transient Navier-Stokes, energy and species con- servation equations are solved numerically by us- ing finite volumes technique. The effect of parameters governing the problem (namely the Rayleigh number, Ra, Lewis number, Le, and thermal to solutal ratio, N) on the tran- sition to oscillatory modes is studied for thermal and solutal buoyancy forces opposing each other. In steady regimes and for moderate Lewis value (Le=10), the flow structure and intensity are found to depend strongly on N (N is considered to vary between 0 and 10 2 ) .F orN = 1, the transition to oscillatory mode is studied as a function of the Lewis number. We show the existence of three distinct behaviours of the critical Rayleigh num- ber. In the first domain (Le > 100), the critical Rayleigh number tends to an asymptotic constant value. In the second domain (for intermediate 4< Le < 100), the evolution of the critical Rayleigh number can be correlated by RaC × Le −1/2 ∝ 1. In the third domain (Le < 4), where the scale for mass and energy diffusion are of the same order; a complex scenario caused by the strong competi- tion between the solutal and the thermal forces is observed.


Gengxu revolt( Gengxu,the year of 1910) was a serious political and military crisis for Guangdong government in the late Qing dynasty. Although the revolt only lasted two or three days with ups and downs,Guangdong government committed some mistakes in dealing with the movement. The mistakes are inadequate preparations before the revolt,wrong strategies for suppressing the revolt,and failing to cope with the aftermath carefully and skillfully.


A real-time adaptation scheme is proposed for the online customization of mode transition controllers designed offline via blending local mode controllers. It consists of the desired transition trajectory model, the active plant model, and the mode transition controller. The active plant model, which incorporates local mode information, is initially trained offline to capture the desired transition trajectory and controls. Afterward, the active plant model is adapted online via structure and parameter learning to capture the input/output relationship of the nonlinear system to be controlled. Likewise, the blending gains portion of the mode transition controller is determined offline and is adapted online via structure and parameter learning to track the desired transition trajectory. The control sensitivity matrix and the one-step-ahead predicted output of the controlled system are used to develop the desired blending gains of the mode transition. The control sensitivity matrix and the predicted output are determined from the active plant model. The proposed adaptation scheme is illustrated for a hover-to-forward-flight mode transition control of a helicopter encountering parametric changes and wind disturbances.


This paper explores the current demand-supply disjuncture for appropriately qualified and experienced staff for community services in Far North Queensland and addresses the question 'How can a local service sector respond to this emerging issue?' In 2006 the Australian Institute of Health and Welfare undertook a review of the available literature on the community-services workforce and identified shortages of qualified staff and skill deficits among current staff as common themes. While workforce development has emerged as an area of research interest within organisation studies, there is little focus on the issue in the third-sector, yet is a critical component of community-services workforce development. This research involved a co-operative inquiry between a regional university and community-service providers. Its aims were to map the local experience of the current demand-supply disjuncture of appropriately qualified and experienced staff; to identify and develop local 'agency'/action to support capacity-building of individuals and organisations within the context of key national and state strategic initiatives; and to develop a wider research and action agenda in partnership. Data was collected through participant observation in, and audio-taping of, the inquiry group's conversations. The main processes used within the group were self-reflection on experiences, informal questioning within organisations, and exploration of strategies developed to date and proposed in response to the issue. The data included information on the nature and extent of the local issue and strategies and findings from the shared inquiries of the cooperative group. The data set was analysed for local themes, in constant comparison with national themes, and is presented as a conceptual framework that emerged in conversation. The findings informed immediate local practice and the development of research and development agendas, in partnership with local community-service agencies.


OBJECTIVE: To comprehending the effects of the trimetazidine on the ventricular arrhythmia in old myocardial patients. METHODS: Total 58 cases (29 pairs) of coronary heart disease/old myocardial infartion patients were studied; the major matching limitations are: age, sex, infarcted position, infarcted time, hypertension or not (the grade),diabetes or not. The study is randomized, pair- matched, crossing and single-blinded clinic study, the statistic analysis of valance (ANOV) was used. RESULTS: The incidence of ventricular arrhythmia was remarkably decreasing in statistic difference(P0.05)after trimetazidine treated; and especially decreased the incidence of the ventricular arrhythnda in activities(p 0.05);For more severe ventricular arrhythmia (above the grade Lown3),the using of trimetazidine also showed more significant positive effects(P≈ 0.01). CONCLUSION: For the ventricular arrhythmia following by OMI, besides the routine treatment, the trimetazidine could also play an important role, with the usage decreasing of other anti-arrhythmia drugs.


To efficiently operate a robot in unknown environments, a robot should be able to perform a variety of tasks in parallel. The reported work investigates the parallelism involved in sensing for moving and stationary obstacles, while a robot is executing a planned motion. Three specific parallel behaviours are investigated, avoid collision, follow the leader, and wall following. The reported work was carried out on a LABMATETM mobile robot, equipped with Polaroid Corp. Ultrasonic range finders. The parallel implementation was undertaken on a network of Transputers, using the OccamTM programming language. OccamTM is a trade mark of the INMOS Group of Companies LABMATETM is a trade mark of TRC corporation.


Objective: Pleural biopsy plays an important role in the differential diagnosis of pleural disease. Though pleural biopsies using Vim-Silverman type needle, Abrams needle, Cope needle, Tru-Cut needle, video-assisted thoracoscope and bronchofibroscope are popular in obtaining pleural tissues, these methods have some disadvantages. The tissue obtained is small, the procedures are complicated, and they may cause trauma. The aim of this study is to evaluate the feasibility and safety of using trocar forceps, a new technique for pleural biopsy. Methods: Thirty patients with pleural effusion underwent parietal pleura biopsy at the anterior axillary line. We inserted the trocar into the pleural cavity perpendicularly, pulled off the core-needle, inserted the biopsy forceps into the canula, and then held the canula with one hand and carefully pinched the body of the biopsy forceps with the other hand. We then opened the biopsy forceps, gently pushing both the canula and the biopsy forceps to increase pressure against the pleura and ultimately closed the forceps to pull off the tissue sample. Results: Pleural tissue was successfully obtained in 29 patients (96.6%), 21 (70.6%) of which con-firmed the pathological diagnosis of the first biopsy. In 16 patients (76.2%), a definitive diagnosis was made on the basis of the first biopsy. Neither muscle nor fat was observed microscopically. The average size of tissue sample obtained using trocar forceps was 2.1±1.3mm. Pneumothorax occurred in 4 patients (13.3%). Fourteen (46.6%) patients had pleuralgia and 3 patients had hemorrhage (10%). Conclusion: Parietal pleural biopsy with trocar forceps is simple, safe and effective.


Semiconductive Ga2O3 nanoribbons have been synthesized via hydrogen-assisted thermal evaporation at 1000 °C. The width of the nanoribbons could be controlled by adjusting the content of hydrogen in a mixture of carrier gases. The room-temperature photoluminescence spectrum reveals that there exists a strong blue emission band centered at 430 nm. The blue emission is mainly attributed to the oxygen vacancies in the Ga2O3 nanoribbons. We have fabricated a Schottky junction diode, utilizing individual Ga2O3 nanoribbons, and studied its electrical transport properties. The measured current−voltage characteristic exhibited clear rectifying behavior with a turn-on voltage of 0.5 V and a rectification ratio of 2.5 × 104 at ±2 V.


Abstract The Eisenstein series corresponding to quadratic forms of type (𝑓/2, 4𝑁, χ) (𝑁 is a square-free natural number) are constructed using the bases of the spaces of Eisenstein series given in [Kachakhidze, Georgian Math. J. 13: 55–78, 2006].


An investigation of nonideal superconducting properties of inhomogeneous tin alloys reveals that the behavior of such samples represents a diverse set of phenomena intimately related to the nature of the inhomogeneities. Resistive temperature and field transitions are presented along with critical field data, magnetization curves, and remnant moment measurements. Several inhomogeneous samples are shown to possess very unstable magnetization curves and to show flux penetration at fields less than the bulk critical value. Annealing can make the magnetization more or less ideal, or produce very little change, depending on the nature of the inhomogeneity and the way it is altered in the process. Annealing sharpens the resistive transition temperature curve when more impurity goes into solution. It also can produce a large change in the apparent transition temperature. Samples examined represent both positive and negative surface energy materials containing either predominantly normal state or superconducting ...


Abstract Classroom dialogue provides significant opportunity for students to build on their understanding of a subject. It is also a vector through which the educator can assess progress in their lessons (Alexander, 2008). The purpose of this study was to explore what effect a specific form of classroom dialogue (the Socratic seminar) has on student engagement, and consequently, their learning.