In order to explain the core of art Creation,Heidegger put forward the thrust of truth in his famous"the Origin of the work of Art",Chinese Mr.Shi Tao advanced a proposal called"shenyu"in the hua Yu Lu.The two theories have traditional Spiritual characteristics of their own,but they have much in common in context.In the standpoint of how creation works,the another tries to explain the two difficult and abstract theories and compare the impotant relations between what the painter is and what the paint is really like.


The aim of this short note is to explain how the arguments of the "closing lemma with time control" of F. Abdenur and S. Crovisier (arXiv:1111.4206) can be used to answer Question 1 of the article "Instability for the rotation set of homeomorphisms of the torus homotopic to the identity" of S. Addas-Zanata.


Objective: To investigate the extent and qualitatively synthesize open science practices within research published in the top five sports medicine journals from 01 May 2022 and 01 October 2022. Design: Meta-research systematic review Data Sources: MEDLINE Eligibility Criteria: Studies were included if they were published in one of the identified top five sports medicine journals as ranked by Clarivate. Studies were excluded if they were systematic reviews, qualitative research, grey literature, or animal or cadaver models. Results: 243 studies were included. The median number of open science practices met per study was 2, out of a maximum of 12 (Range: 0-8; IQR: 2). 234 studies (96%, 95% CI: 94-99) provided an author conflict of interest statement and 163 (67%, 95% CI: 62-73) reported funding. 21 studies (9%, 95% CI: 5-12) provided open access data. 54 studies (22%, 95% CI: 17-27) included a data availability statement and 3 (1%, 95% CI: 0-3) made code available. 76 studies (32%, 95% CI: 25-37) had transparent materials and 30 (12%, 95% CI: 8-16) included a reporting guideline. 28 studies (12%, 95% CI: 8-16) were pre-registered. 6 studies (3%, 95% CI: 1-4) published a protocol. 4 studies (2%, 95% CI: 0-3) reported the availability of an analysis plan. 7 studies (3%, 95% CI: 1-5) reported patient and public involvement. Conclusion: Sports medicine open science practices are extremely limited. The least followed practices were sharing code, data, and analysis plans. Without implementing open practices, barriers concerning the ability to aggregate findings and create cumulative science will continue to exist.


572 consecutive cases of histologically proven nasopharyngeal carcinoma(NPC) with CT-scanning before radiothearapy from Apr. 1984 to July 1987 seen at our hospital were analyzed retrospectively. . Basing on the true extent of primary tumor displayed by CT, an attempt was made to screen the leading prognostic factors according to the Cox regression model The results showed that the accurate T-staging, which must refer to CT or MRI, was the most important independent factor influencing the treatment outcome, and the next important factor was N-staging. Among the 15 factors related to the T-staging, the significant factors influencing the survival was presented in the order of proportional hazard. It wes emphasized that the completed control of the disease of carotid sheath area was one of the key factors improving the survival rate of NPC.


Ground penetrating radar(GPR) signal processing has all along been a hard task because of its poor signal-to-noise ratio(SNR) of the raw GPR signals and almost "blind" about the latent targets what we want to detect beforehand.A new approach that uses Independent Component Analysis(ICA),a newly developing blind signal processing(BSP) technique,to GPR signal processing has been proposed in this paper.With the help of FastICA algorithm,it has successfully extracted quite weak target signals from the raw GPR data with much strong background.So the SNR of the GPR signal and the detection performance of the GPR have both improved greatly.The ambiguities of rightly sequencing and the sign uncertainty problems of separated target signal components in ICA practical use have also been overcome.Two examples,FDTD simulated and field-test GPR data for local targets,such as landmines and underground pipelines,to be processed by FastICA,are included to demonstrate the effectiveness of the approach.Quite ideal results are got from them.


Cataloging field recordings of American Indian lan- guages presents many challenges. The cataloger may deal with anti- quated physical formats as well as with problems determining con- tents and applying appropriate subject headings. The Archives of Traditional Music (ATM) at Indiana University, Bloomington, is a repository of such recordings and has been cataloging them on OCLC since 1983. A general description of the ATM precedes a dis- cussion of two specific collections that exemplify the recordings held at the Archives as well as some of the difficulties inherent in cataloging such materials.


The precise identification of ancient refrigeration systems is problematic, since nearly every technological advance is the result of long accumulation of human experience shaped according to the environmental, cultural, social and climatic conditions of the period and region. Besides, the scarcity of firsthand documentary records doubles the problem. Therefore, in the course of the discussions, being aware of the difficulties of the subject matter, it was an important phase to fill the gap in the area of history of refrigeration technology by the help of the hospital cases in Anatolia. It takes the form of a case study that focuses as much on the context and motives for the possible refrigeration technologies used and applied in historical hospital buildings.


The National Vegetation Survey (NVS) databank (GIVD ID AU-NZ-001) is New Zealand's primary archive for plot-based vegetation data and holds data from 77,000 releves and over 19,000 permanent plots. The NVS databank provides a unique record, spanning more than 50 years, of indigenous and exotic plants in New Zealand's terrestrial ecosystems. A broad range of habitats are covered, with special emphasis on indigenous forests and grasslands. The databank is both an electronic database and physical archive, which stores field recorded plot sheets, maps, and photographs from over 1,200 vegetation surveys. Data in the NVS databank has been built up over many decades by contributions from vegetation scientists and New Zealand environmental conservation agencies. The principal goals of the NVS databank are to provide a secure repository for such data and to ensure quality data are readily available to end-users in different organisations. A website (http://nvs.landcareresearch.co.nz) provides general background information, protocols for data deposit and use, and the ability to conduct online searches of metadata and to request data. Data within NVS have been used to support reporting requirements for the Convention on Biological Diversity, Framework Convention on Climate Change, NZ Resource Management Act, and the Montreal Process. They also assist in ecological restoration, and have been significant in enabling New Zealand to address issues of current concern that were unforeseen at the time of data collection. These include assessing the impacts of climate change and carbon storage in indigenous ecosystems. In 2007 a new extended and robust data model, based in part on the US VegBank design, was built and in 2009 a freely available data entry and analysis tool for vegetation plot data stored within the databank called 'NVS Express' was released. Future goals are to improve Internet services, develop additional online analysis and mapping capabilities, improve integration with plant trait data, and support the Veg-X data exchange schema.


In today's society, there is a challenge to detect and to avoid exposure to harmful and lethal chemicals. This remains an issue to public health and has not been addressed adequately. To address this challenging issue, the objective of this paper is to provide a unique perspective in designing and building a custom-made mobile handheld chemical detection (CHCD) device that can detect harmful and lethal chemical gases (NO2, N2, CO, CO2, LPG, CH4, CNG, C2H5OH, NH3, H2 and others) in public and in private gathering places. This mobile handheld device can relay the information of the chemical concentration levels detected to smartphone or tablet or laptop in any place at any time. Applications of this useful mobile CHCD prototyping device include detection of harmful gases in public and in private gathering places such as subway stations, shopping malls, airports, and residential houses. Additionally, this mobile CHCD device provides an alternative and affordable resource for people to have and use it as an advance warning system within the proximity of dangerous areas. Keywordschemical detection; mobile communication; remote sensing.


Two samples of Tapioca starch of different viscosities have been crosslinked with sodium trimetaphosphate, epichlorohydrin, and phosphorus oxychloride. Of these crosslinking agents, epichlorohydrin is the most efficient, requiring only 0.01 to 0.15% of the reagent on the weight of starch. It is noted that tapioca starch having initially a high viscosity requires less amount of the crosslinking agent for stabilization of its paste viscosity as compared to the starch sample having low initial viscosity.


This study attempts to find out the incidence of non melanoma skin cancers in psoriasis patients. Psoriasis is a chronic, relapsing, inflammatory and proliferative skin disease associated with cutaneous and systemic diseases.


Equilibrium humidities of the larvae of 3 medically important tick species, the Rocky Mountain wood tick, Dermacentor andersoni (Stiles), the American dog tick, Dermacentor variabilis (Say), and the Cayenne tick, Amblyomma cajennense (Fabricius), were determined. Equilibrium weights can be maintained in the larvae of all 3 species at humidities down to approximately 80% to 85% relative humidity. Survival experiments with larvae of D. variabilis and A. cajennense demonstrate that the longevity is abruptly shortened at humidities below the equilibrium humidity.


Practice Change: The project was conducted on three acute care nursing units and included fourteen registered nurses who served in the charge nurse role. Each charge nurse attended a five hour TeamSTEPPS and SBAR training session and contributed to revisions of the Charge Nurse Handoff Form. The revised Handoff Form was arranged in SBAR format and included: description of patient problem, patient name and diagnosis, supporting information (i.e. patient history, medications and tests), analysis of pertinent medical history (i.e. vital signs and diet), and suggestions for future actions to resolve problem.


MSH receptors are one of the possible targets to specifically attack melanoma cells by photodynamically active agents bound to melanotropic hormones. To attack effectively metastatic melanoma the presence of the hormone receptor has to be proven in metastases. Radioactive labeling of melanotropic hormones allows us to check for the presence of intact receptors. We tried to develop a non-radioactive immunological method as a first step to work out therapeutic strategies to attach photodynamically active porphyrins to the surface of melanoma cells.


In this study, the characteristics of flow within and around a crossroad connected symmetrically with four roads are numerically analyzed by using a two-dimensional well-balanced HLLC finite volume model. As results of simulations and analyses, the numerical model employed in this study describes relatively well the complex water surface in a crossroad according to the conditions of inflow and road slope. Moreover, the predicted temporal and spatial variations of water depths in a crossroad and outflows at two downstream boundaries agree relatively well with laboratory measurements.


While analog computing is attractive for implementing machine learning (ML) processors, the paradigm requires chip-in-the-loop training for every processor to alleviate artifacts due to device mismatch and device non-linearity. Speeding up chip-in-the-loop training requires re-biasing the circuits in a manner that the analog functions remain invariant across training and inference. In this paper, we present an analog computational paradigm and circuits using "shape" functions that remain invariant to transistor biasing (weak, moderate, and strong inversion) and ambient temperature variation. We show that a core Shape-based Analog Compute (S-AC) circuit could be re-biased and reused to implement: (a) non-linear functions; (b) inner-product building blocks; and (c) a mixedsignal logarithmic memory, all of which are integral towards designing an ML inference processor. Measured results using a prototype fabricated in a 180nm standard CMOS process demonstrate bias invariance and hence the resulting analog designs can be scaled for power and speed like digital logic circuits. We also demonstrate a regression task using these CMOS building blocks.


Roger Williams contended for the organic separation of the institutions of government and religion. He argued that the state could only enforce the "second" tablet of the Ten Commandments. With regard to the "first" tablet-the one concerning the relationship between a person and deity-Williams declared that the proper role of government was to create a climate in which each person could exercise his/her conscience responsibly.


The single most common cause of the withdrawal or restriction of the use of marketed drugs has been QT-interval prolongation associated with polymorphic ventricular tachycardia, or torsade de pointes, a condition that can be fatal. This review summarizes the current knowledge about molecular and clinical predictors of drug-induced QT-interval prolongation and torsade de pointes and discusses how new molecular predictors of drug action might be incorporated into drug-development programs and clinical practice. A general approach to drugs suspected of causing this problem is presented.


This article focuses on the quality of the environment and effects that polychlorinated biphenyls (PCB) have on it. PCBs are characterized in the historical point of view; they make their way through atmosphere, hydrosphere and lithosphere. Another part of the article focuses on the situation concerning PCB in Slovakia and the effects it has on animals and human being, and also on the current trend in research of these substances.


As for a doudle pyramidal central configuration in 6-body problems,the case when its bese is a concave polygon is studied.By advancing several assumptions according to the definition of double pyramidal central configuration and deducing two theorems and two corollaries on this subject,the essential and sufficient conditions to form a double pyramidal central configuration with a concave quadriateral base are demonstrated.


Snapchat is a camera and ephemeral messaging application popular among young adults. Due to its self-destructing content and playful features, Snapchat is often associated with more trivial uses. However, the platform has added functionality to support consumption of news. To understand how users perceive and interact with news content on Snapchat, we conducted semi-structured interviews with 19 users of the platform, focusing on their use of Snapchat during breaking news events, including the 2016/2017 US presidential election and inauguration. Through the lens of Network Gatekeeping, our research explains how users consume breaking news content on Snapchat. We unpack users' ambiguous perceptions of news reliability on Snapchat, and demonstrate how this contrasts with traditional news consumption. Our research also describes how users' mental models of how Snapchat works—specifically their theories about how the platform curates news content—shape their judgments of reliability, media bias and authenticity.


Poster: "ECR 2011 / C-1506 / Comparison between efficacy of partial splenic coil and particle  embolization with just particle embolization in management of hypersplenism  " by: "A. Rasekhi, G. Shadmani, S. Ostad; Shiraz/IR"


The result depicts that based on intra-linguistic analysis, English, and Indonesian idioms which contain gender discourse are in the forms of noun, phrases, Sub-clause, Simple sentence, Elliptical sentence, Compound, Complex, and Compound-Complex sentences. Based on the meaning and reference analysis, it is known that such idioms have various meanings: strength and weaknesses, success, marriage, sexuality, negative things, and wisdom. Besides, seen from the doer, the idioms can refer to men, women, and men and/or women. Based on Critical Discourse Analysis (CDA), such idioms can be analyzed based on the aspects of action, context, history, power, ideology and representation, which, then, are known that: (a) men are assumed as representative in various affairs and things (esp. in success and goodness); (b) men are active in marriage and sexuality; (c) women take more part in domestic domain; (d) women become negative metaphor; and (e) there is unequal relationship between women and men.


The F/A-18 aircraft has an integral Engine Monitoring System (EMS) for automatically capturing selected engine parameters during take-off and when a parameter exceedance is detected inflight. These data are then available to maintenance personnel to aid them in diagnosing faults and/or the presence of degraded components. The difficulty is that these data are most likely to correspond to transient engine operation whereas most of the available fault diagnostic procedures have been derived from steady-state information. In this paper, two procedures are outlined for diagnosing a limited range of engine faults from transient data. In the first method, uncertainty bands for various parameters at a fixed point in the take-off acceleration transient were derived from F/A-18 data acquired during normal operation over a two-year flying period. It was found that two compressor related faults could be easily detected from these data. In the second method, analytical redundancy is used to relate certain engine faults to the resultant changes in the dynamic characteristics of the engine. In essence then, the techniques provide new tools for identifying engine faults from transient data.


Face recognition is one of the most important abilities which we use in public security and for identity verification for physical and logical access. It is well known that many image-based face recognition algorithms perform well, when constrained (frontal, well illuminated, high-resolution, sharp, and full) face images are acquired. However, their performance degrades signi?cantly when the test images contain variations that are not present in the training images. Face recognition in constrained acquisition conditions is one of the most challenging problems that have been actively researched in recent years. There are many factors low resolution, poor illumination, pose variation, occlusion and relative motion between the sensor and objects in the scene to substantially degrade performance more than the other quality. The work described in this paper is interested in Motion Blur. Motion Blur is often present in real-world images and


Melt-SHS (self-propagating high-temperature synthesis), based on the SHS process and oxide reaction method, was used for preparation of TiB_2/Al composites. The mass ratio of two reactants, Ti powder/TiO_2, in initial powder mixture was varied from 0:1 to 1:0. The results showed that the 5 wt% TiB_2/Al composites could be successfully produced by a reaction of aluminum powder, TiO_2, and B_2O_3 in Al melt at 950 °C, while the reaction rate was slow. The addition of titanium powder helps to reduce the content of Al_2O_3 and destroy the coating structure of Al_2O_3 covered TiB_2 particles, which leads to the acceleration of reaction process and improvement of particle concentration. A significant improvement was that TiB_2 particles were dispersively distributed when the mass ratio of Ti powder/TiO_2 was 2:3. As a result, the 5 wt% TiB_2/Al composites fabricated by melt-SHS process with modified reactants ratio showed excellent tensile properties with the ultimate tensile strength as high as 114.24 MPa. Besides, the composite also showed superior ductility.


Abstract : The purpose of this Graduate Management Project (GMP) was to develop a validated survey instrument to gather crucial feedback from deployed Forward Surgical Teams (EST) for use by the Army Medical Department Center and School (AMEDD C&S) in the developmental evolution of the Program of Instruction (POI) for the Army Trauma Training Center (ATTC), currently operating out of Ryder Trauma Center, Miami, Florida. Three critical processes or phases were used to assure validity in the initial design of this tool. After a thorough literature review, an initial template was developed with assistance from the Executive Officer (XO) and another instructor assisted in staffing this tool through the ATTC. The second phase was to have the Survey Administrator, AMEDD C&S, automate and modify the survey to comply with Center and School training feedback objectives and the Army Surgeon General's Balanced Scorecard. Finally, the tool went through a second audit conducted by the ATTC and was piloted for content through the 801st FST at Fort Campbell. The objective of developing a solid instrument for the ATTC was completed during the course of this project. Ultimately, utilizing this tool to gather feedback will be essential to evaluate the Army's current trauma training program and enhancing the quality of care we deliver on the battlefield.


Two different effective thresholds for the onset of nonlinearity in the dielectric and piezoelectric coefficients of donor-doped lead zirconate titanate (soft PZT) piezoceramics at electric ac fields Ec1≈100 V/cm and Ec2≈1 V/cm are found. Both are characterized by a scaling behavior x=x0+A[E−Ec)/Ec]φ above the respective threshold, where x is the dielectric or piezoelectric coefficient. The values of the effective exponent φ are apparently independent of the particular ceramic system which suggests a universal behavior in soft PZT. We suggest that the nonlinearity is dominated by the dynamics of domain walls in a randomly pinned medium.


Objective:research the functionality of insulin β cell and the characteristics of insulin resistance of the patients with non alcoholic fatty liver disease(NAFLD).Methods:Research subjects were collected from the teaching hospital of Qingdao University and the People's Hospital of Jimo City.The total number was 60 with NAFLD(experiment group) 30 and non-NAFLD(control group) 30.Compare the glycosylated hemoglobin,BMI,blood-fat,blood sugar and insulin level of the two groups.In addition,evaluate the insulin resistance with HOMA-IR method,the bottom area of the insulin curve reflects the overall states of how insulin βcell secretes insulin.△I30/△G30,HOMA-βevaluate the secreting functionality of the early phase insulin and late phase insulin,the parameters and their affecting factors are analyzed with correlation.Results:The weight,BMI,TC,TG,HDL-C,LDL-C,HbA1c,0 min,30 min,120 min blood sugar are all higher than those of the control group(t=4.877,3.677,2.388,3.589,2.616,2.21,3.850,2.254,3.913,P=0.001,0.001,0.020,0.002,0.031,0.001,0.014,0.001,0.02).The HOMA-IR of NAFLD was also greater(t=4.482,P=0.001),there are little difference between the curve bottom area of early phase secreting and late phase secreting(P0.05).HbA1c,TC,0 min,60 min,120 min blood sugar is correlated with IR(R=0.542,R=0.675,R=0.832,R=0.499,R=0.974,P0.05);HLD-c,0 min blood sugar,0min insulin is correlated with early phase secreting(R=-0.556,R=0.519,R=0.529,P0.05);0 min blood sugar,0 min insulin was correlated with late phase secreting(R=-0.771,R=0.767,P0.05).Conclusion:Patients with non alcoholic fatty liver disease have insulin resistance and insulin β cell is not impaired in the early stage.


Data fidelity is inspected for the first time for wavelength-converted RZ TDM 80- and 160-Gb/s data using four-wave mixing in a silicon waveguide. Open eye diagrams and error-free operation is shown for demultiplexed 10-Gb/s tributaries.


Pharmaceutics is an important curriculum which include abundant contents,highly practical and narrative characteristics.Combining the characteristics of pharmaceutics,the author summarize the reform of pharmaceutics teaching through six aspects.This article discusses how to put the teaching reform into practice to enhance the quality pharmaceutics teaching of cultivate the student's creative power and learning ability in pharmaceutics course through personal teaching experience and practice.


Abstract The discussion in this paper has been focused on the strength of Polyurethane elastomers, data on other materials being presented for comparison and to illustrate factors that affect strength. Although the literature on Polyurethane elastomers is voluminous, only in recent years has it been widely recognized that plastic domains exist in most polyurethane formulations of technological importance. Evidence for domain formation and aspects of domain morphology are discussed in recent reviews. The morphology of domains in segmented polyurethane elastomers is more complex than of those in triblock elastomers and has not been studied extensively, although progress is being made, indicated by the discussions in recent publications and references cited therein. In view of the complexities of fracture and the limited information on the morphology and time-dependent mechanical properties of polyurethane elastomers, only general relations between strength and chemical structure have thus far been establish...


The all-transglycolytic synthesis of lacto-N-biose I (Galβ1–3GlcNAc) and 3′-sialyl-lacto-N-biose I (NeuAcα2–3Galβ1–3GlcNAc) was performed. The disaccharide lacto-N-biose I was obtained by use of p-nitrophenyl β-d-galactopyranoside as the donor, 2-acetamido-2-deoxy-d-glucopyranose as the acceptor and Xanthomonas manihotisβ-d-galactosidase as the catalyst. The reaction was shown to be regiospecific, with a high molar yield (about 55%) with respect to the donor. Lacto-N-biose I obtained by this method was used as the acceptor for a subsequent enzymatic reaction catalyzed by Trypanosoma cruzi trans-sialidase in which 2′-(4-methylumbellyferyl)-α-d-N-acetylneuraminic was used as the donor of the N-acetylneuraminil moiety. The reaction generated the product, 3′-sialyl-lacto-N-biose I, regiospecifically and with a molar yield of about 35%.


Watterlogging is an important cause of yield loss on the cracking grey clays. We conducted a field experiment to quantify its impact on growth and yield. In terms of management, the results demonstrates the importance of ensuring adequate bed height and allowing excess water to leave the field quickly, definitely not later than 48 hours after irrigation.


The behavior for separation and enrichment of Pd by MCI-GEL-Guanidine hydrochloride (GCl) system was studied. The results showed that the resulting complex of Pd with guanidine hydrochloride could be adsorbed completely by MCI-GEL resin in diluted hydrochloric acid. The extraction efficiency of Pd could be optimized and increased to 99.0%, when a molar ratio of guanidine hydrochloride to palladium was set at 1 and the concentration of hydrochloric acid was 0.05 mol/L and the flow rate was controlled at 5 mL/min. The other metals had no significant interference in the selective absorption of Pd. The extraction capacity of MCI-GEL resin for Pd was 5.2 mg/g. The elution of palladium from the resin could be achieved with a mixed mixture of 1% hydrochloric acid and 20 g/L thiourea as a eluent at a flow rate of 1 mL/min. 3 mL eluent was required for the complete elution of 0.5 g palladium adsorbed on the saturated resin.


Introduction
 The outcome hematopoietic stem cell transplantation (HSCT) in a cohort of children with chemorefractory leukemia is poor. The incidence of relapse exceeds 50% and survival varies from 10 to 40%. Additional attempts at remission induction with various combinations of chemotherapy are unlikely to improve the outcome and will contribute to toxicity. We hypothesized that personalized targeted therapy combined with high-dose chemotherapy may improve the outcome of allogeneic hematopoietic stem cell transplantation in a cohort of pediatric patients with refractory leukemia. Bcl-2 and CD38 were chosen as potential targets due to frequent expression in pediatric acute leukemias, availability of marketed targeted therapies, venetoclax and daratumumab, and expected non-overlapping toxicity profile of these agents and the conditioning regimen.
 Materials and methods
 A total of 16 pts with chemorefractory disease (T-ALL - 2, AML - 8, JMML - 6, 12 male, 4 female, median age 5,7 years), underwent HSCT between November 2017 and June 2018, median follow-up - 3 months (1,6-7). All pts were transplanted from haploidentical donors, had active disease (AD) at the moment of SCT, for 12 (75%) pts it was the first allogenic HSCT, for 4 pts it was the second HSCT. Median bone marrow leukemia burden before cytoreduction was 22% (3-75). Bcl-2 expression on the tumor cells was detected in all pts (100%) with the median expression of 69% (0,7-100), CD38 expression was detected in 10 pts (AML=7, ALL=2, JMML-1) with the median expression of 96% (71-100). Ten pts received treosulfan-based conditioning, 3 - busulfan-based and 3 -TBI-based. GVHD prophylaxis included tocilizumab at 8 mg/kg on day -1, post-transplant bortezomib and abatacept at 10 mg/kg on day -1, +7, +14, +28. Three pts received thymoglobulin 5mg\kg. According to the expression of Bcl-2 and CD38 on tumor cells, 9 patients (56%) received Daratumumab (anti-CD38 monoclonal antibody) on day -6, 15 patients (94%) received venetoclax at 300 mg/m2/day on days -7 to -2.
 TCRαβ+/CD19+ depletion of PBSC with CliniMACS technology was implemented in all cases. The median dose of CD34+ cells in transplant was 11 x106/kg (range 7-18), α/β T cells - 40x103/kg (range 11- 139).
 Modified (CD45RA-depleted) donor lymphocyte infusions (DLI) were administered to 15 pts, 9 pts received modified DLI on day 0.
 Result
 Primary engraftment was achieved in 13 (81%) of 16 pts. The median time to ANC and platelets recovery was 14 days (11-22). Engraftment was 100% (10 of 10) among patients with acute leukemia and 50% (3 of 6) among patients with JMML. Three patients with JMML had early disease progression. There were no significant toxic effects after HSCT and no cases of transplant-related mortality. The median NK- cells count by the day +30 was 0,185 x 106/ml (range 0,019- 0,472), the median levels of αβ T cells and gd T cells were 0,045 x 106 /ml (range 0 - 0,364) and 0,07 x 106 /ml (range 0 - 0,349, respectively. Acute GVHD grade 1-2 was developed in 2 pts (15%), none of them required systemic immunosuppressive therapy. There were no cases of chronic GVHD. One (7,6%) patient with AML relapsed on day +61. Three pts (1 with AML and 2 with JMML) died from disease progression, 1 patient with JMML died from complications after the second HSCT. At the moment of reporting 12 pts (9 of 10 with acute leukemia and 3 of 6 with JMML) are alive, in complete remission with a median follow up of 3 months (1,5-7m).
 Conclusion
 We suggest that addition of venetoclax and datatumumab to the backbone of myeloablative haploidentical HSCT with αβ T cell depletion is not associated with increased toxicity and may lead to improved early outcomes in a cohort of pediatric patients with chemorefractory acute leukemia. This approach can be further tested in a prospective trial with the goal to increase the anti-leukemic efficacy of HSCT.

 No relevant conflicts of interest to declare.


Cardable cellulosic fibers having improved water and fluid absorbency are made by incorporating therein an alkali metal or ammonium salt of a copolymer of acrylic acid and methacrylic acid prepared by a process wherein the two monomers are mixed together in ratios during the polymerization so that the amount of copoly mer chains substantially richer in methacrylic acid moi eties than the total ratio of acrylic acid and methacrylic acid monomers included in the copolymerization pro cess and the number of copolymer chains considerably lower in degree of polymerization than the copolymer average are minimized.


A dielectric ceramics/TiO2/single-crystalline silicon nanomembrane (SiNM) heterostructure is designed and fabricated for high performance flexible thin-film transistors (TFTs). Both the dielectric ceramics (Nb2O3–Bi2O3–MgO) and TiO2 are deposited by radio frequency (RF) magnetron sputtering at room temperature, which is compatible with flexible plastic substrates. And the single-crystalline SiNM is transferred and attached to the dielectric ceramics/TiO2 layers to form the heterostructure. The experimental results demonstrate that the room temperature processed heterostructure has high quality because: (1) the Nb2O3–Bi2O3–MgO/TiO2 heterostructure has a high dielectric constant (∼76.6) and low leakage current. (2) The TiO2/single-crystalline SiNM structure has a relatively low interface trap density. (3) The band gap of the Nb2O3–Bi2O3–MgO/TiO2 heterostructure is wider than TiO2, which increases the conduction band offset between Si and TiO2, lowering the leakage current. Flexible TFTs have been fabricated with the Nb2O3–Bi2O3–MgO/TiO2/SiNM heterostructure on plastic substrates and show a current on/off ratio over 104, threshold voltage of ∼1.2 V, subthreshold swing (SS) as low as ∼0.2 V dec−1, and interface trap density of ∼1012 eV−1 cm−2. The results indicate that the dielectric ceramics/TiO2/SiNM heterostructure has great potential for high performance TFTs.


Novel tricyclic Ras farnesyl-protein transferase (FPT) inhibitors are described. A comprehensive structure-activity relationship (SAR) study of compounds arising from substitution at the 3-position of the tricyclic pyridine ring system has been explored. In the case of halogens, the chloro, bromo, and iodo analogues 19, 22, and 28 were found to be equipotent. However, the fluoro analogue 17 was an order of magnitude less active. Whereas a small alkyl substituent such as a methyl group resulted in a very potent FPT inhibitor (SCH 56580), introduction of bulky substituents such as tert-butyl, compound 33, or a phenyl group, compound 29, resulted in inactive FPT inhibitors. Polar groups at the 3-position such as amino 5, alkylamino 6, and hydroxyl 12 were less active. Whereas compound SCH 44342 did not show appreciable in vivo antitumor activity, the 3-bromo-substituted pyridyl N-oxide amide analogue 38 was a potent FPT inhibitor that reduced tumor growth by 81% when administered q.i.d. at 50 mpk and 52% at 10 mpk. These compounds are nonpeptidic and do not contain sulfhydryl groups. They selectively inhibit FPT and not geranylgeranyl-protein transferase-1 (GGPT-1). They also inhibit H-Ras processing in COS monkey kidney cells and soft agar growth of Ras-transformed cells.


A new class of high strength steel with excellent toughness, ductility, and good weldability is emerging world-wide, named as High Performance Steel (HPS). HPS can be designed as having an optimized balance of these properties to give maximum performance in bridge structures while remaining cost-effective. Hybrid steel girder, comprising mild steel for top flange and web, and HPS for bottom flange, has outstanding potential for steel-concrete composite bridge. A study is performed to compare the cost differences between bridge designs using conventional mild steel Fe 410, high tensile steel Fe 590 and a combination of the two grades of steel. Two cases of span supported and un-supported during construction are considered for comparison. Maximum flexural stresses, maximum deflection, weight and cost are compared for 40m span steel-concrete composite bridge for both the unsupported and supported conditions of the bridge span during construction. It has been found that hybrid steel girders are most economical, for which there is a saving of about 34.7% in steel weight and 29.1% in steel cost in comparison to the mild steel girder bridge for the un-supported span case, while in supported span case it is 50% and 46%, respectively. However, the maximum deflection is found to increase more than two times the permissible deflection of L/600 for total dead and live load, for both HPS as well as hybrid steel girder in comparison to the mild steel girder case Keywords— High performance steel, Bridge, Deflection, Cost, Hybrid


With the growing volumes of intelligence, surveillance, and reconnaissance (ISR) data captured by a myriad of sensors for motion imagery, satellite imagery and data, radar feeds, and aerial surveillance, government agencies need to address the challenges posed by these "big" datasets to ingest data, analyze content, and turn datasets into valuable intelligence. NetApp provides a scalable, modular, and flexible storage solution targeted at solving issues for the ISR space and focused on a unified single pool of storage that can handle the demanding workflow requirements of sophisticated ISR environments.


Olefins constitute as much as one-half the neutral oil obtained by low-temperature carbonization of low-rank coals. It is difficult to separate these olefins from other materials in the tar fractions. However, without a prior separation, a large fraction of these olefins can be converted to mixtures of primary alcohols by hydroformylation with H/sub 2/ + CO in the presence of dicobalt octacarbonyl as a catalyst (oxo reaction). Several neutral oils were so treated and the alcohols separated via their borate esters. The highest yields of alcohols (25 wt percent) were obtained from the neutral oil of a lignite tar. The carbon number distribution of the alcohols was determined by mass-spectrometric analysis of the trimethylsilyl ethers. C/sub 9/- to C/sub 27/-alcohols were produced; an unusually high concentration of C/sub 20/-alcohols appeared in the products from lower rank coals. Nuclear magnetic resonance spectra of the alcohol mixtures showed that an ''average'' molecule contains from 1 to 3 branched methyl groups. By using /sup 14/CO, and assuming that each olefin will react with one CO, the percentage of olefins originally in the tar can be determined from the radioactivity of the product. An advantage of this analytical method is that no separation ofmore » the olefins, or their oxo product, need be made. By this procedure, the neutral oil from the lignite tar was shown to contain about 50 percent olefins.« less


This paper introduces the concept and characters of dataspace, and presents a framework for dataspace integration and management system. Based on the framework, this paper further summarizes research works on data model, integration, query, update, storage, index, evolution and systems of dataspace. Challenges and future work on dataspace research are analyzed.


ABSTRACT
 The effects of the application of iron coke in hydrogen-rich blast furnace atmosphere on the softening and melting performance of burden were studied.The results indicated that with the increase in hydrogen content, the cohesive zone of mixed burden became narrower and the permeability of charge was improved, and the suitable hydrogen content was 10vol.-%. The application of iron coke could promote the iron ore reduction and carburizing of iron, decrease the melting temperature by 1–10°C, decrease the dripping temperature by 5–16°C, narrow the cohesive zone, improve the air permeability with S value decrease of 3.19–13.87 kPa °C, and reduce the dissolution loss of coke and ensure the skeleton function of coke. The suitable burden structure was confirmed as follows, i.e. the ratio of pellets and sinter is 4:6, and the ratio of iron coke and coke is 2:8.


Due to frequent link failures in multi-hop wireless networks, redundancy can be an important feature. For example, when planning the structure of a backhaul mesh network for public access, it is common to introduce redundant nodes in the mesh network. These are called redundant, because they do not increase the network capacity under normal operation, due to the shortest-path metric of the routing protocol. Instead, their sole purpose is to increase the network reliability by providing failover links when a link in the shortest-path fails. This paper shows how to estimate the optimal number of redundant nodes for a given topology. In order to do so, a method to calculate the additional network reliability that results from introducing a redundant node to a given topology is also proposed.


Big Data concern la rge-volu me, comple x, growing data s ets with mult iple, autonomous sources . W ith the fas t development of networ king, data storage, and the data collection capacity, Big Data a re now rapidly e xpanding in a ll s cience and engineering doma ins , including phys ical, b iologica l and bio med ical s ciences . This paper pres ents a HACE theore m that characterizes the features of the Big Data revolution, and propos es a Big Data proces s ing model, fro m the data mining pers pective. This data-driven model involves demand-driven aggregation of informat ion s ources , mining and analys is , us er interes t modeling, and s ecurity and privacy cons iderations . We analyze the challenging is s ues in the data-driven model and als o in the Big Data


According to the spirit of medical and health reform and the survey data from Sichuan Province,mechanism,volume, structure,focus,methods and other issues of health financial compensation are analyzed;advices on increasing the total amount, optimizing the structure and improving the performance of health spending are proposed.


"In The Future of the Image, Jacques Ranciere develops a fascinating new concept of the image in contemporary art and film, showing how art and politics have always been intrinsically intertwined. Covering a range of art movements, filmmakers such as Godard and Bresson, and thinkers such as Foucault, Deleuze, Adorno, Barthes, Lyotard and Greenberg, Ranciere shows that contemporary theorists of the image are suffering from religious tendencies. He argues that there is a stark political choice in art: it can either reinforce a move towards radical democracy, or help create a new reactionary mysticism. For Ranciere there is never a pure art: the aesthetic revolution must always embrace egalitarian ideals. " -- Dust jacket.


The magnetic susceptibility of A-type bead like zeolite is measured as a function of temperature between liquid helium and room temperatures under low pressure of oxygen gas. The zeolite specimen employed in the present work has micropores, the diameter of which is 5 Å. The magnetic susceptibility of oxygen molecules adsorbed by zeolite is evaluated from the results obtained before and after oxygen adsorption. The temperature dependence of the susceptibility of oxygen exhibits a sharp peak at about 50 K, suggesting that oxygen molecules incorporated into zeolite induce the formation of an antiferromagnetic state. The present results are compared with the magnetism of oxygen adsorbed on the surface of graphite and physisorbed into slit-shaped micropores in activated carbon fibers.


In situ attempts to measure the sun's angular momentum loss in the solar wind and thereby to test the Weber and Davis description of the magnetic coupling between stellar rotation and winds have thus far produced widely divergent and inconclusive results. A new estimate for the solar loss rate in the ecliptic plane has been derived from the Helios spacecraft data. By intercomparing measurements made by the twin probes over the full 0.3/1.0 AU baseline of their orbits, it is possible to eliminate the systematic instrumental offsets from the true radial direction that have plagued rate (field+particles) near the solar equator is approx.0.2--0.3 x 10/sup 3/ dyn cm sr/sup -1/, about one-quarter the Weber and Davis prediction and much lower than previous spacecraft estimates, and (2) the distribution of that flux between particles and field stresses is very near the 1:3 ratio of the model, when an important contribution from the heretofore neglected solar wind ..cap alpha..-particles is accounted for. Though few by number in the solar wind, the ..cap alpha..-particles' flow speed and direction in general differ from that of the protons, largely offsetting the latters' angular momentum content (+0.15--0.2 x 10/sup 30/ for the protons, -0.1 x 10/supmore » 30/ for the ..cap alpha..-particles, plus being in the direction of corotation with the Sun). As to the small value reported for the total flux, theory and observation can be reconciled by moving the mean Alfven radius, r/sub A/, in to 12 R/sub sun/, a figure that is consistent with coronal models more realistic than the single polytrope formation used by Weber and Davis.« less


The Factors of Children and Housing Environment Related to the Incidence of Pneumonia among Underthree Children in the District of Banjar Pneumonia in the District of Banjar still become an important health problem, in spite of the disease tackling program has been performed in long time period. Some teories reveal that the factors of children and housing are related to the incidence of pneumonia. The objective of this study was to analyze relationship between the factors of children and housing and the incidence of pneumonia among underthree children in the District of Banjar. This study used case control design. The case was underthree children aged 12 - 35 months diagnosed with pneumonia by the clinicians in health care centers during a period between April and June 2003, and lived in the District of Banjar. Control was underthree children of the same age lived nearby those in case group. Total sample was 150 individuals, comprising 75 in case and 75 in control group. The dependent variable in this study was the incidence of pneumonia in underthree children, while the independent variables were age, sex, immunization status, nutritional status, birthvveight, vitamin A supplementation, house ventilation, humidity, sunlight, house location, house type, floor type, wall type, kitchen location, smoke hole, house density, presence of transmission source, cigarette smoke, kitchen smoke, and mosquite repellent smoke. Data analysis ware done descriptively and Inferential. The descriptive analysis was presented as cross tabulation and percentage. Inferential analysis was done using logistic regression test %with significance leve. of 95% (p < 0.05) to identify relationship between the independent and dependent variables, and to estimate risk (Odds Ratio) of the risk factors of the incidence of pneumonia in underthree children. Results revealed that the variables having significant relations with the incidence of pneumonia in underthree children were the presence of transmission source, with OR =13,497 (95% Cl: 3,109 � 58,590); sunlighting in house with OR = 11,942 (95% Cl: 2,583 � 55,215); lower nutritional status, with OR = 4,985 (95% Cl: 1,853 � 13,413); densely inhabited house, with OR = 4,366 (95% Cl: 1,635 - 11,659) ;vitamin A supplementation, with OR = 3,537 (95% Cl: 1,509 � 8,291); and age of 12 - 23 months, with OR = 3,114 (95% Cl: 1,287 � 7,536), whereas another variables did not show any relations to incidence of pneumonia among underthree children in the District of Banjar. From this study can be suggested that for giving the enlightenment to public about prevention and early detection of peumonia/ ISPA, nutritional development and health care underthree children, and housing sanitation. Then, if there was a family member who having ISPA, they must immediately threated so it would not advance to pneumonis and would not infects another family member.


Reaction between thiamine diphosphate hydrochloride (H3TDPCl) and methylphenyltin dichloride in water at pH ca. 5.6 afforded the title complex, which was studied by X-ray diffraction and IR and Raman spectroscopy in the solid state and by multinuclear NMR spectroscopy (1H, 13C, 31P, and 119Sn) in aqueous solution. The crystals of this compound are formed by the oxygen-capped cluster cation [{SnMe(HTDP)(OH)}3O]+, an OH- counterion, and water of crystallization. The cation has 3-fold symmetry, and the tin atom has coordination number 6 and a distorted octahedral coordination polyhedron. The HTDP- anion is bis-monodentate bridging between two Sn atoms via two of the oxygens belonging to the terminal phosphate of the ethyl diphosphate side chain [Sn−O = 2.074(3), 2.100(5) A]. The thiamine moiety has F conformation, with torsion angles C(2)−N(3)−C(3,5')−C(5') = −5.8(11)° and N(3)−C(3,5')−C(5')−C(4') = −83.0(10)°, and the ethyl diphosphate side chain is folded back, directing the pyrimidine and thiazolium rings...


The authors analyze the geopolitical and geographical location of the territory of Russia, characterized by harsh climatic conditions. The complication of the already harsh living conditions in the regions of Russia by weather anomalies creates additional difficulties for the population. Analysis of historical data on crop failure due to weather anomalies and due to mass or partial famine in different regions of Russia allows us to identify the pattern of occurrence of climate anomalies, predict difficult weather conditions and prepare measures to ensure life safety of population. Creating an early warning system using the products of scientific and technological progress is able to provide the population with a safe life in the modern world under any weather anomalies.


Global warming Analysis and prediction system is an application made Specifically for desktop purpose. This software Implement certain ways of analyzing and predicting the major causes of global warming such as power plants, oil drilling, deforestation etc. Also show the details about the Global warming. Each user first makes their login to server to show their identity. This software keeps the track of shared complaint and gets the specific Global warming related information very easily. The overall data will be showed in the statically manner.


Evaluation of functional gastmintestlnal dlsorders In autonomic neumpathy: Evaluation of functional gastrointestinal disorders in autonomic neuropathy: The clinical diagnosis of gastrointestinal autonomic neuropathy requires the exclusion of organic diseases since visceral neuropathy is only associated with unspecific Symptoms. Until now. no diagnostic clinical tools are available t o evaluate visceral neuropathy directly. Because of poor correlation between intestinal and extra-intestinal neuropathies. visceral neuropathy can only be considered by functional disorders of the gut, e.g. motility dysfunctions. Suitable methods to determine gastrointestinal dysfunction are manometry, pKmetry, radiology. scintigraphy and exhalation tests. In future. new technical approaches may extend the possibilities t o detect gastrointestinal autonomic neuropathy. These are the electrogastrogram (EGG) by which dysrhytmia of eiedricai Signals from pacemaker cells of the stomach might be detedable and additional methods that allow systematic recording of neural projections between the gastrointestinal tract and the central nervous System (CNS) in humans. By means of these new techniques afferent projections (cortical evoked potential~, magnetic resonance encephalography. positron emission tomography. functional magnetic resonance tomography) and efferent projections from the CNS t o the gastrointestinal tract (transcranial magnetic Stimulation) can be investigated. durch das Elektrogastrogramm (EGG) und zum anderen Methoden. die eine systematische Untersuchung der Nervenbahnen zwischen Verdauungstrakt und ZNS beim Menschen ermöglichen. Durch diese Verfahren können afferente Projektionen (kortikale evozierte Potentiale, Magnetenzephalographie. Positronenemissionstomographie, funktionelle Magnetresonanztomographie) und efferente Nervenbahnen vom ZNS zum Castrointestinaltrakt (transkranielle Magnetstimulation) untersucht werden.


Abstract : Migration from an existing information technology system to a new system presents many managerial challenges. There are technological challenges associated with running the old system, maintaining data integrity and bringing the new system online all without seriously impacting daily operations. There are human factors to consider like resistance to change and conflict management. In addition, organizational issues like management support and cross functional communication channels need to he addressed. This thesis reviews the technical migration from an operational NetWare network to Windows NT completed at the Defense Manpower Data Center (DMDC) in Monterey, CA. The DMDC case presents a typical set of issues that an IT manager is likely to face when implementing technology driven change. Technical, human and organizational factors of technical change are discussed. A list of lessons learned and a set of technical management guidelines are derived from analysis of the DMDC case. Details of Windows NT 4.0 and 5.0 features are included.


The aim of this study was to conduct operating analysis of two styles of bow (RITSUREI and ZAREI) for martial artists and average students, and to compare their kinematics characteristic of. Subjects of this study were healthy men (n=33) who were martial artist group (MA, n=18) and average student group (AS, n=15). Subjects conducted RITSUREI and ZAREI three times each. Results of paired t-test, on angular degree parameter of RITSUREI, MA made smaller angular degree of the upper limbs and angular degree of the neck than that of AS. regarding time parameter components, the total time of ZAREI, from beginning of it to stopping, from stopping of it to end, and from beginning of RITSUREI to stopping were significantly shorter than that of AS. MA made several characteristic shown in text. BUDO bow is regarded as practical bow even in social rule when bow teaching is conducted


The number of students pursuing degrees and graduating in political science is growing again after the discipline experienced falling or stagnant enrollment numbers at all academic levels in the 1990s, according to data in the latest Digest of Education Statistics (2005). After experiencing a growth in enrollments and degrees awarded in the 1980s, political science departments reported falling enrollments in the early 1990s and stagnant numbers of degrees awarded in the later half of the 1990s (Mann 1996; 2002). Political science departments began to report increasing enrollments starting in 1998–1999 (Mann 2002), reflected in the increase in graduation numbers beginning in 2002.


This article presents the results of a cognitive and evolutionary study devoted to the order of appearance of definite and indefinite articles in language development. It critically examines the conventional postulate on earlier appearance of the definite article and later appearance of the indefinite article. Research on concreteness, abstractness, and degrees of perception as related to linguistics justifies the historical simultaneousness of the appearance of explicit definite and implicit indefinite articles.


Article is devoted to the analysis of possibilities of creation of the general theory of a policy. I suggest choosing as a basis for creation of such theory the system political paradigm. The special attention thereupon is given to the system structural-functional theory.
system theories; structural functionalism; political analysis; political culture; general theory of policy


A series of La2-x1Srx1CuO4+delta/La(2-x2)Srx(2)CuO(4+delta) multilayers were epitaxially grown on (001) LaSrAlO4 and (001) SrTiO3 substrates by laser ablation, where x1 = 0.0, 0.08 (underdoped) and x2 = 0.24, 0.32, 0.45 (over-doped). Before the depositions of each multilayer, all of the single layers were deposited and characterized, and then the multilayers were deposited by using the same deposition condition except shifting targets for laser ablation. These multilayers are highly c-axis oriented. Several modulation wavelengths of the sublayers were selected for preparing the multilayers. The resistance measurements of these single layered films of La2-x1Srx1CuO4+delta, La2-x2Srx2CuO4+delta, and multilayers of La2-x1Srx1CuO4+delta/La2-x2Srx2CuO4+delta were performed and compared. The transport measurements suggest that the charge redistribution may be a dominant factor for the superconducting transition temperature in low temperatures.


In this paper we propose a new algorithm for lossless compression of remote sensing images, based on distributed source coding. The objective of this algorithm is to achieve low-complexity encoding, with compression performance as close as possible to a full-complexity coder. The complexity reduction is obtained by coding each spectral channel separately, whereas high coding efficiency is achieved through joint decoding. Experimental results on hyperspectral images show that the proposed algorithm has significantly better performance than JPEG-LS, with similar complexity. We also provide profiling results on a LEON-3 architecture.


This paper describes an experimental investigation of fabric-wrinkling behaviour as measured on a Thermobench, fabric stress-relaxation measured under both constant and varying ambient conditions, and inter-fibre friction of a series of three wool fabrics tested in both their 'aged' and 'deaged' states. Deaging of these fabrics was achieved by four different methods. It is shown that simply soaking in water at room temperature is an effective and practical deageing procedure for wool fabrics.


The amount of glycyrrhizinic acid in traditional Chinese herb for cold preparation was determined by RP-HPLC with the column of Alltima C18 5μ(Lot No.2980 Part No.88056 Length 250mm Serial No.02060484.1 ID 4.6mm),and the mobile phase of V(methanol)∶V(water)∶V(acetic acid) =65∶33∶2 at a flow rate of 0.8 mL/min with UV detector at 254nm.The column temperature was 45℃.A good linear relation was obtained in range of 3—86μg/mL.The average recovery of the method is(100.9% with)the RSD of 0.36%(n=5).This method is accurate,simple with a good recovery,and applicable for quality control to the analysis of traditional Chinese herbs for cold preparation.


The thesis presents a measurement of the properties of the Higgs particle, performed by using the data collected by the ATLAS experiment in 2011 and 2012. The measurement is performed by using a three-dimensional model based on analytic functions to describe the signal produced by the Higgs boson decays. The model includes the information provided by the uncertainty measured event-by-event. A maximum likelihood fit is used to obtain an unbiased estimate of the mass, the signal strength and the decay amplitude of the Higgs particle.


To protect and improve the environment, reduce pollutant emissions, and promote ecological civilization, China implemented "the Environmental Protection Law of the People's Republic of China" on 1 January 2018. However, what is the impact of strict environmental regulation on foreign direct investment (FDI)? The study uses the data from 287 cities in 30 of China's provinces between 2003 and 2019 and constructs an intensity difference-in-difference model to test the impact of China's environmental "fee-to-tax" on FDI. Empirical results show that environmental "fee-to-tax" significantly boosts FDI. The "pollution halo" hypothesis is confirmed, and the findings hold up through robustness tests. In addition, the heterogeneity test found that environmental "fee-to-tax" mainly promoted FDI in the eastern and central regions but not significantly in the western regions. Further expansion found that environmental "fee-to-tax" can effectively reduce the emission of pollutants. The results provide important policy implications for deepening the environmental protection tax reform and optimizing FDI.


Designers of oscilloscopes have made great strides in improving the instruments' power, accuracy, and ease of use. Nevertheless, achieving the units' specified performance depends on careful equipment selection and operation. A key part of a modern oscilloscope is the probe—an accessory that is all too easy to overlook. The scope probe is a crucial link in the measurement chain. The probe can affect both your measurement results and the circuit under test and is more than just a signal conduit between the circuit under test and the scope.As part of the measurement chain, the probe affects both measurement results and circuit-under-test operation. All probes present resistive, inductive, and capacitive loading; the challenge is to ensure that these effects stay within acceptable limits. The main source of probe-related measurement errors is capacitive loading. Resistive loading is usually the least worrisome of the three effects because it is least likely to induce nonlinear behavior in your circuit. Although excessive current drain can cause nonlinear response, such response usually isn't a problem when you use a 10-MV probe. The most common resistive-loading difficulty results from the voltage divider that consists of the circuit's output resistance and the probe's own resistance:


Стоимость единицы прибыли неуклонно растет, и для бизнеса пришло время задуматься о цифровых платформах, позволяющих успешно конкурировать в борьбе за платежеспособных клиентов.
 The cost per unit of profit is steadily increasing, and it is time for businesses to think about digital platforms that allow successfully compete for effective demand by joining the ecosystem, using specialization and theoretically unlimited scaling of business processes. One of the architecture options such a platform that connects the clouds, edge computing and 5G / 6G technologies, — hyperscaler.


: The problem of wastewater and its purification challenges are inseparable from sustainable development, in other words, water must meet the needs of current and future generations without mortgaging the supply capacity and their satisfaction. A challenge of waste managing worries professionals, where does the objective of this study to characterize the bacteriological quality of liquid effluents from a private dairy industry located in Bechar (Southwest of Algeria). The analyzed bacteriological parameters target mainly contaminating microorganisms (Faecal coliforms and fecal streptococci) that are recommended by the national regulation and the international regulation of WHO, knowing that we deemed it necessary to add to these the following parameters: Enumeration The a total of 10 samples revealed a high rate of faecal contamination. The average loads recorded for the various microorganisms counted were out of the ordinary, where the total and faecal coliforms had an average of log 10 4.38 and log 10 4.11 cfu/100mL respectively. The faecal streptococci were log 10 4.38 cfu/100mL. The contamination with sulphite reducing clostridia was averaged log 10 2.57 spores/100mL. However, the average of total aerobic germs was log 10 5.55 cfu/100mL.This results originally from the absence of liquid effluent treatment that are evacuated in ventilated basins, mainly three basins, each one pours the volume of wastewater towards the other basin and so on before being rejected to the sewerage network; so that, the present microorganisms progressively degrade the organic matter which it contains, but on the contrary, it will increase the microbial load. The untreated discharge of these wastewaters undoubtedly constitutes a threat to public health and to the ecosystem. The large amount of generated liquid effluents by the agri-food industry in general and from the dairy industries in particular, requires purification and recycling that can be valued in several areas namely irrigation in the agricultural sector and many others.


There has been constant resonance of feminine image misrepresentation in most narratives since the (re)invention of video-films in Nigeria, Ghana, and indeed across the African continent. In spite of the binary struggle between the (presumed) chauvinist filmmakers and their feminist counterparts, masculinity always (re)emerges in new forms or topoi to dominate femininity. Consequently, there seems to be a paradigm shift on the (mis)representation of women that reinforces Laura Mulvey's sexual voyeuristic objectification of the feminine gender as reflected in near-nude costumes as well as sexually larded scenes that are common sights in African films, particularly those from Ghana. Employing the historical-analytic and observation methods, this article examines three selected films:  The Maid I Hired (2010), Why Did I Get Married? (2007) and To Love a Prince (2014) by Frank Rajah Arase (FRA), an African filmmaker of Benin (Edo) extraction who largely operates in the Diaspora, to foreground and highlight the voyeuristic imprints in Ghanaian films (Ghallywood), which tend to demean the feminine gender in the context of African culture that hegemonizes the male folk.


The successful career development of a manager in the contemporary context is closely connected with the attainment of a certain level of professionalism. The need for professionalism development entails the demand for regular skill upgrading according to the current requirements.


Abstract Model experiments using methyl α-d-galactopyranoside 6-sulfate have implied that the Carlson conditions (1 M sodium borohydride and 0.05 M sodium hydroxide at 45°C) for the release of O-linked oligosaccharides from glycoproteins do not cause significant loss of sulfate ester groups. However the more vigorous conditions used to release N-linked oligosaccharides are more likely to cause considerable sulfate loss from a galactoside 6-sulfate as a result of 3,6-anhydride formation. Experiments with dextran sulfate suggested that sulfate loss due to oxirane formation was also not significant under the Carlson conditions. These results were supported by experiments with [35S]sulfate-labelled human rectal mucus glycoprotein.


In English law, offences related to dishonesty are governed by the Theft Acts 1968 and 1978, the Theft (Amendment) Act 1996 and the Fraud Act 2006. These Acts are not a restatement of the common law and its numerous statutory additions but they do provide a code of the most important offences of dishonest dealing with the protection of property (with the notable exception of forgery and conspiracy to defraud). This chapter deals with the offence of theft. It offers a detailed review of the concept of dishonesty in the light of the redefinition of that concept by the Supreme Court in Ivey v Genting Casinos and its acceptance in Barton.


Objective: Salt-sensitivity is associated with exaggerated blood pressure (BP) increase in response to salt load and considered an independent predictor of cardiovascular events in normo- and hypertensive individuals. LCZ696 is an angiotensin receptor neprilysin inhibitor (ARNI) expected to increase ANP levels while simultaneously blocking the AT1-receptor. This study compared the effects of LCZ696 and valsartan on BP and NT-proBNP in Asian patients with salt-sensitive hypertension (SSH). Design and method: Randomized, double-blind, double-dummy cross-over study in 72 patients with SSH (10% or higher increase in MAP when switching from 50 mmol/day to 320 mmol/day for 7 days each). Patients received LCZ696 400 mg once daily and valsartan 320 mg once daily for 4 weeks each. Office BP, ambulatory blood pressure measurements (ABPM) and NT-proBNP were assessed at baseline and on Day 28. Results: LCZ696 and valsartan significantly lowered office SBP and office DBP from baseline with larger reductions with LCZ696 compared to valsartan (SBP: -13.3 mmHg vs. -5.9 mmHg; adjusted mean difference between groups: -7.6 mmHg, p = 0.002; DBP: -6.2 mmHg vs. -4.3 mmHg; adjusted mean difference between groups: -2.0 mmHg, p = NS). LCZ696 and valsartan also significantly lowered ambulatory SBP, DBP, MAP, and pulse pressure from baseline with larger reductions with LCZ696 compared to valsartan for daytime, nighttime, and 24 h intervals. The largest treatment difference between groups was observed at nighttime (adjusted mean difference; SBP: -5.1 mmHg, p < 0.001; DBP: -2.6 mmHg, p = 0.004; MAP: -4.0 mmHg, p < 0.001). Baseline plasma NT-proBNP levels were comparable between groups. On Day 28, NT-proBNP levels were significantly reduced by 41% with LCZ696 and by 28% with valsartan (p < 0.001 for both). NT-proBNP at week 4 was significantly lower (20%) with LCZ696 compared to valsartan (p = 0.001). Conclusions: Treatment with LCZ696 400 mg compared to valsartan 320 mg once daily for 4 weeks provided superior office and ambulatory blood pressure reduction and larger hemodynamic unloading of the heart. These results may suggest an added long-term benefit for LCZ696 related to reduction of end-organ damage and cardiovascular events in patients with SSH.


It is a common concern that pricing pressure by powerful buyers discourages suppliers'R&D investments. Employing a simple monopsonist competitive upstream industry framework, this paper quali…es this view in two respects. First, the monopsonist has an incentive to subsidize upstream R&D which yields more upstream R&D and higher pro…ts in both industries than the monopsonist's commitment to higher prices. Secondly, in the presence of knowledge spillovers, the monopsonist's subsidization is strictly higher than the social planner's one, ceteris paribus. JEL Classi…cation: O31, O32, L13, L20


The aim of this study was to investigate the antibacterial effect of the crude starter "kpètè-kpètè" and lactic acid bacteria used during the production of "tchoukoutou." To achieve this, a total of 11 lactic acid bacteria and 40 starter samples were collected from four communes. The samples were tested on 29 gram + and − strains by disk diffusion method. The minimum inhibitory and bactericidal concentrations of starter and lactic acid bacteria were determined by conventional methods. Organic acids, sugar, and volatile compounds were determined using the HPLC method. The "kpètè-kpètè" displays a high antibacterial activity against the tested strains. The most sensitive strain was S. epidermidis (12.5 mm) whereas the resistance strain was Proteus mirabilis (8 mm). All the tested ferment has not any inhibitory effect on Enterococcus faecalis. The lactic acid bacteria isolates of Parakou showed the highest (17.48 mm) antibacterial activity whereas the smallest diameter was obtained with the ferment collected from Boukoumbé (9.80 mm). The starters' chemical screening revealed the presence of tannins, anthocyanin flavonoids, triterpenes, steroids, reducing compounds, and mucilage O-glycosides. These compounds are probably the source of recorded inhibition effect. The lactic acid bacteria of the "kpètè-kpètè" could be used to develop a food ingredient with probiotic property.


As a large amount of steel is produced for the industrialization and modernization of Vietnam, a correspondingly large quantity of steel slag is also released annually. Besides, the demand for mortar is increasing due to urbanization, especially for the high-strength and durability mortar used for important constructions and structures in aggressive environmental areas. This study aims to carry out further research into high-strength mortars incorporating ground granulated blast furnace slag (GGBFS). The control mixture was designed with a water-to-binder ratio of 0.2, and the amount of silica fume used was equal to 25% of the total binder amount by mass. Four other mixtures were designed using GGBFS to substitute for 15, 30, 45, and 60% of cement by mass. The engineering properties of fresh and hardened mortars were comprehensively investigated, especially the durability properties. The microstructure of these mortars was also examined using scanning electron microscopy. Test results show that replacing 15 or 30% of cement with GGBFS yields an improvement in mortar's strength and durability properties. All the mortars in this study show excellent qualities with high strength, low water absorption, and high resistance to chloride attack. Moreover, the presence of GGBFS reduces the shrinkage of mortar caused by the drying process. Doi: 10.28991/CEJ-2022-08-05-07 Full Text: PDF


The polaron has been of interest in condensed matter theory and eld theory for about half a century, especially its strong coupling limit. It was not until 1983, however, that a proof of the asymptotic formula for the ground state energy was nally given by using diicult arguments involving the large deviation theory of path integrals. Here we derive the same asymptotic result, E 0 ?C 2 , and with explicit error bounds, by simple, rigorous methods applied directly to the Hamiltonian. Our method is easily generalizable to other settings, e.g., the excitonic and magnetic polarons. The polaron Hamiltonian of Frr ohlich 1] is a model for the Coulomb interaction of one or more electrons with the phonons of an ionic crystal. In the course of time it was also seen to be an interesting eld theory model of non-relativistic particles interacting with a scalar boson eld, and it was widely studied 2, 3, 4, 5, 6, 7] in both contexts. The model has one dimensionless coupling constant, , and it was noticed very early that there seems to be a qualitative diierence in the ground state between the weak coupling regime, well described by perturbation theory 8], in which the electron is spread out, and the strong coupling regime in which the electron appears to be trapped in a phonon hole of its own making. By now it seems doubtful that such a trapping actually occurs 7, 9, 10], but it remains true that the calculation of the ground state energy, E 0 (), is very diierent in the two regimes. The strong coupling theory was studied by Pekar 2] (see also 3, 4, 5])


present, construction machinery as an important part of engineering construction, and occupies a decisive position. In the process of operation, all kinds of faults often occur in construction machinery. If we want to avoid these faults, we must correctly use the machinery, find out the faults through a variety of detection technologies, and take effective maintenance measures to eliminate the hidden trouble in time, reduce the probability of failure, and ensure the improvement of the operation efficiency of construction machinery. Construction machinery is widely used in infrastructure projects. In order to give full play to its performance in operation, the role of fault detection and maintenance of construction machinery is particularly important. In order to ensure the quality of engineering construction in China, it is necessary to avoid engineering machinery failures as much as possible. Therefore, relevant departments must do a good job in troubleshooting and maintenance of engineering machinery, clarify the impact of mechanical failures on mechanical application, and propose corresponding solutions, thus greatly improving the application effect of machinery and the production efficiency of enterprises.


The paper introduces a heuristic structure optimization algorithm of the radial basis probabilistic neural network(RBPNN).A moving medium centers covering hypersphere algorithm is proposed to initially select potential hidden centers vectors of the first hidden layer from all the training samples,then the genetic algorithms further prunes the structure of RBPNN,and determining the matching controlling parameters of kernel function of RBPNN.The experimental results showed that the algorithm can effectively quicken the optimization speed,decrease the computation complexity,and simplify the structure of the RBPNN.


The growing population of India is facing many problems. One of the challenging problem is lack of sufficient parking space. If we consider the problem of cities, then the traffic has become the crucial factor for any city. The situation is such that on any given working day approximately 40% of the roads in urban India are taken up just for parking the vehicles. In this study, we have surveyed the location of city Gandhinagar, capital of Gujarat, where parking is very important and provide a way through which we can efficiently utilize the spaces.


Rabbits receiving a single dose of 1000 r showed a considerable decrease in the iodine number of the serum lipids 24 hours after irradiation. A gradual return to that died. The decrease in iodine number was approximately parallel to changes in total fat and fatty acid levels. Less change was noted after irradiation with 300 to 500 r. Although the decrease in serum lipid iodine number after irradiation with 1000 r corresponded in degree to that of starving animals, it was not considered to be the result of starvation, but of abnormal fatty acid metabolism. (Abstr. Japan Med., 2: No. 5, May 1962).


OBJECTIVE
to identify psycho-social reactions of Palestinian families to personal losses during the Second Intifada in the West Bank and the Second Lebanese war in Israel.

METHOD
Narratives were collected from support group participants in the west Bank and in individual and family therapy in Israel. the narratives were qualitatively analyzed to identify themes relating to psycho-social reactions to war losses.

RESULTS
themes emerging from the west Bank support groups' narratives mostly mirrored those gathered in the therapy sessions in Israel. In both sites, bereaved families exhibited similar psycho-social reactions to war-related losses. Both groups coped with loss collectively and in congruence with their common ethno-cultural background. Also, religious beliefs provided explanations. the loss experiences were ongoing and accumulative for participants in the west Bank, while in Israel it was mostly a single event.

LIMITATIONS
Both studies referred solely to war-related losses.

CONCLUSIONS
the relationships of each population group with the State of Israel shaped their political, national and personal reactions to the loss. Families of "shahids/martyrs" in the west Bank gained socio-political respect, while in Israel, Arab citizens suffering war-related losses did not receive the same political respect from Israeli society, but were awarded sympathy by their communities. In Israel the situation is further complicated since the State is both the enemy and provider of material support, comfort and rescue.


Taking 207 national highway engineering from Eryuan to Baiquan section as an example,the author analyzes the key links of pavement reconstruction using impact compaction technique from six aspects,in order to perfect reconstruction technology changing cement concrete pavement into bituminous concrete pavement and offer a reference for pavement reconstruction.


Glioblastoma multiforme (GBM) is the most common brain cancer. Front-line systemic therapy with temozolomide is often ineffective due to O6-methylguanine-DNA-methyltransferase (MGMT)-mediated resistance. Dianhydrogalactitol (VAL-083) is a bi-functional DNA N7 cross-linking agent that crosses the blood-brain barrier and demonstrated cytotoxic activity independent of MGMT in vitro. The main goal of this clinical trial was to determine an appropriate dose for Phase II/III trials in refractory GBM. METHODS: Open-label, single-arm Phase I/II dose-escalation study in patients with histologically-confirmed GBM, previously treated with radiation and must have failed both temozolomide and bevacizumab, unless contraindicated. The study utilized 3 + 3 dose-escalation design. Patients received VAL-083 on days 1, 2, 3 of a 21-day cycle. RESULTS: 30 GBM patients were enrolled across 8 dose cohorts ranging from 1.5 to 50mg/m2/d. No drug-related severe adverse events were reported, and myelosuppression was mild at doses ≤40mg/m2/d. Dose limiting toxicities (DLT) consisting of thrombocytopenia were observed at 50mg/m2/d. Platelet nadir occurred around day 20, and DLT-related symptoms resolved rapidly and spontaneously without concomitant treatment. Pharmacokinetic analyses show dose-dependent linear systemic exposure with a short 1-2h plasma terminal half-life; Cmax ranged 739-1130ng/mL (5.1-7.7 µM) at 40mg/m2/d resulting in calculated CNS concentrations within the IC50 range observed for multiple GBM cell-lines in vitro. Preliminary analysis shows increasing dose-dependent median survival with median OS = 9.0 months at doses ≥30mg/m2/d vs. 4.4 months at doses <10mg/m2/d. An expansion cohort of up to 14 patients has been initiated at 40mg/m2/d. A small cohort (n = 3) at an interim 45mg/m2/d dose will also be studied, and the expansion cohort may be continued at this higher dose if safety data warrant. CONCLUSIONS: VAL-083 dosing appears limited by myelosuppression; however, 40mg/m2/d dose exhibited favorable safety profile, with a trend toward improved survival vs. lower doses. Updated safety and efficacy data from the expansion cohort will be presented. ClinicalTrials.gov Identifier NCT01478178.


By the end of Operation Protective Edge in August 2014, the Israel Defense Force (IDF) claimed to have discovered and destroyed more than 30 tunnels spanning from beneath Gaza into Israeli territory. Hamas officials have praised these tunnels as an innovative approach to fighting an asymmetric war with a far more conventionally powerful Israel. The purpose of this case study is to examine the complexity of Hamas' vast tunneling network by assessing the motivations behind the group's decision to construct the network, to identify the factors that enabled Hamas to engage in such a complex engineering task, and to assess the level of effectiveness of the tunnel network both strategically and tactically against the IDF. Disclaimer Editor's Note: This article forms part of a series of related case studies collected in this Special Issue and should be viewed in the context of the broader phenomenon of complex engineering by violent non-state actors. Readers are advised to consult the introductory and concluding papers for a full explanation and comparative analysis of the cases. Acknowledgements This work was supported by Sandia National Laboratories, Contract #1525332. Any opinions, findings, conclusions and recommendations in this issue are those of the authors and do not necessarily reflect views of Sandia National Laboratories or the U.S. Department of Energy. This article is available in Journal of Strategic Security: http://scholarcommons.usf.edu/jss/vol9/iss1/8


Pneumatic injector device was currently developed as a novel therapeutic option for facial scars. Through needle-less manner, injected particles such as hyaluronic acid immediately produce tissue volume augmentation and subsequently induce dermal microtrauma resulting in skin remodeling. There has been several transient adverse events has been reported such as pinpoint bleeding, transient erythema and edema and focal tenderness. Herein, we reported our two cases of milia formation after pneumatic injector therapy. Physicians should be aware of the possibility of secondary milia formation after pneumatic injector therapy for scar remodeling. Figure 1: (a) Linear depressed scar on the chin. (b) Improvement of the scar and two milia that developed at the pneumatic injection site after three treatments. (c) Erythematous depressed patches on the left nasal ala. (d) Three tiny milia formed at the scar site treated by pneumatic injection. Citation: Choi SY, Ahn GR, Kim BJ, Kim MN, Hong CK. The Formation of Multiple Milia Induced by Pneumatic Injector Therapy for Scar Remodeling. J Clin Investigat Dermatol. 2017;5(2): 2. J Clin Investigat Dermatol 5(2): 2 (2017) Page 02 ISSN: 2373-1044 considering that calcified through epidermal implantation or by providing a stimulus for nodules developing after neonatal heel sticks have been well documented, especially in high-risk neonates after repeated skin puncture [5]. We could hypothesize that mechanical stress induced by the pneumatic injector caused micro-trauma to the basement membrane of the skin and resulted in plugging of the pilosebaceous or eccrine sweat ducts, leading to development of multiple milia at the injection site. Since both two cases used same HA material for pneumatic injection treatment the possibility of injected HA promoted the growth of keratinous cyst by its volumizing effect or further activation of cellular signal transduction pathway is still remaining. We reported our two cases of milia formation after pneumatic injector therapy. Physicians should be aware of the possibility of secondary milia formation after pneumatic injector therapy for scar remodeling. Further clinical experiences or pre-clinical investigations of pneumatic injection treatment using various injection materials are expected.


It is well known that knee meniscectomy is one of the major knee surgeries, which induces thigh muscle atrophy (Akima and Furukawa, 2005; Ericsson et al., 2006). In general, traditional high-intensity exercise training (≥ 70% 1-repetition maximum: 1RM) improves skeletal muscle morphology and function (ACSM, 2009), but it appears that this method is not practical and may even be dangerous in patients with knee meniscectomy. On the other hand, KAATSU training (≤ 30% 1RM) can produce muscle hypertrophy and does not decrease vascular function (Ozaki et al., 2013; Yasuda et al., 2015; Yasuda et al., 2016). Additionally, recent studies (Nakajima et al., 2015; Hiraizumi et al., 2016) reported that KAATSU training is quite useful as a rehabilitation method in disorder of bone (femoral head avascular necrosis, femoral medial condyle osteonecrosis). However, it is unclear whether thigh muscle size after knee meniscectomy can be improved with KAATSU training. Thus, the purpose of this study was to examine effect of KAATSU training on thigh muscle size and safety for a patient with knee meniscectomy.


Dental and oral infection problems can be overcome using natural antimicrobial compounds from bacterial endophytic resulted from bacterial fermentation. This study aims to determine the effectiveness of extracts of Andalas endophytic bacterial fermentation products in treating oral cavity infections. Fermentation products was extracted using maceration methods. Antimicrobial activity of Andalas endophytic bacterial fermentation product was evaluated to S. mutans and C. albicans by disk diffusion method. The study showed that the optimum concentration of extract in inhibiting microbial growth that causes oral cavity infections was at  12.5%.


The computer can be applied to effectively and efficiently evaluate/report pupil progress and adapt instruction to the pupils' evaluative variables. Essentially, the computer, through interacting with an information bank, produces an individual or a group evaluation/reporting profile that delineates the precise nature of the pupils' evaluative variables, specifies the extent and nature of pupil progress and communicates this to parents, pupils, and teachers. The computer ultimately interacts with the profile and, subsequently, retrieves, generates, and prints suggestions of instructional components that meet the pupils' evaluative variables.


The aim of this paper analyzes China's North Korea Policy in the 2nd nuclear crisis and suggests Korea's policy alternatives.
Korean peninsula again has suffered serous tension since last October. North Korea acknowledged resuming nuclear program in last October and withdrew Nuclear Non-Proliferation Treaty(NPT) in early 2003.
North Korea aroused nuclear program to give pressure United States coming on negotiation table, to guarantee the survival of Kim jung-il regime, to secure nuclear capability, to press South Korea, and to get state autonomy from China.
With the North Korea's reckless action makes China be a positive coordinator. China thought if North Korea really has a nuclear weapons and increases instability in Korea peninsulat it will hinder for China's long plan for super power through modernization and economic growth in the world. Now China realized that North Korea become from old friend to new challenges. Besides that China faced increased pressures from the United States to take stronger measures to curb Pyongyang's nuclear programme. So China changed her stance from negative posture to positive towards North Korea nuclear issues.
China changed her policy from ideological cooperation to practical cooperation, from isolated policy to core pole of regional diplomacy, and from 'lip-and-teeth' relation to limited military alliance with North Korea.
In conclusion China has relation with North Korea status quo in short term, selective cooperation in the long run.
With the North Korean nuclear crisis South Korea will restore the dislocated Korea-U.S. alliance, make selective cooperation with China, and elastic and strategic cooperation with North Korea.


Three anthocyanins were isolated from the 50% acetic acid extract of the light blue-purple flowers of Campanula medium, 'May Blue'. Among them, a new acylated anthocyanin was elucidated to be delphinidin 3-[6-O-(a-rhamnopyranosyl)-β-glucopyranoside]-7-O-[6-0-(4-O-(β-glucopyranosyl)-p-hydroxybenzoyl)-β-glucopyranoside] (5) as a main anthocyanin, together with two known anthocyanins, violdelphin (4) and delphinidin 3-O-rutinoside-7-0-glucoside (6) as minor anthocyanins. On anthocyanin components, three other cultivars of C. medium were investigated by HPLC analysis, and found that campanin (3) was present in the purple flowers of 'May Purple' as a main anthocyanin, rubrocampanin (1) was present in the pink flowers of 'May Pink' as a main anthocyanin, and purprocampanin (2) and rubrocampanin (1) were present in the purple-red flowers of 'May Purple Margin' as major anthocyanins. From these results, the relations between the flower colors and anthocyanin components were discussed in the flowers of C. medium cultivars.


Relationship Marketing (RM) is defined as engaging in cooperative and collaborative activities with business partners and end-user customers to create or enhance mutual economic value at reduced cost. RM, initially applied between companies, is currently being applied to consumer markets and is studied both theoretically and practically. In service sectors especially, companies use RM strategies to know their customers that would provide long-term profits, to retain them and to enhance relationships. Advances in information and communication technologies are used for that purpose to analyze and predict customers' needs and to develop strategies. From consumers' perspective, relationship quality and relationship satisfaction are the constructs that are developed and studied to understand how consumers perceive RM programs. Relationship quality has had the greatest influence on relationship outcomes, such as objective performance and has been used as a key relational mediator, comprising of the dimensions of trust, commitment and relationship satisfaction. The RM research studies have usually been realized within the context of customer-service provider relationships where face-to-face interactions take place. Today companies use technology to reach their customers via phone, mobile phone, and the Internet. Banks use these technologies most frequently and successfully. The purpose of this study is to understand how the relationships that customers feel towards their providers are affected when service is delivered via technology-based channels and how customers feel when they use technology-based channels. The research involves application of a questionnaire to bank customers in general. More specifically, bank customers that use a particular technology-based service channel to realize their banking operations are randomly selected to form a sample. The model is tested using Structural Equation Modelling with software AMOS V7. The dependencies between several concepts, the existence of a multi-order construct like relationship quality necessitated the use of multivariate analysis. The model uses a widely studied notion that the relational mediator, relationship quality, affects relationship commitment, or loyalty as a relationship outcome. The two constructs preceding relationship quality are technology-based service media characteristics and the perceived performance of interactions on these media, in marketing terms, service channels. The two constructs are mainly designed to measure the critical factors of technology-based service channel usage and the drivers of perceived performance of such interactions. The results of the study confirm the majority of the research hypotheses proposed and that technology-based service interactions do not deplete the relationship quality perceived by banks customers. The ATM users and internet users perceive medium characteristics of technology-based options at differing levels. ATM users perceived privacy, security and interactivity more important compared to internet users, who perceive personalization and efficiency as more important. ATM users also perceive interactivity characteristic as higher in importance which could be related to their need to be directed by a friendly and interactive screen while realizing their operations. Internet users, however, perceive personalization and efficiency as more important. Service firms must prepare personalized screens and messages in order to increase their customers' commitment to their relationships. Efficiency is an important characteristics that both ATM users and internet users perceive as effective in their sense of relationship. In order to do that banks can provide user friendly interfaces that include easy to understand commands, simple to follow menus and sequencing of operations. Perceived trust in technological competence of service provider is an important variable in consumer's perception of higher performance and relationship quality. Service providers can offer new technology-based channels after verifying that consumers can reliably perform their operations. Service failures are the most important and critical incidents that service firms should handle with care. Perceived cooperation to use technology-based mediums is also effective in assessing performance of technology-based interactions. Service firms can use alternative methods so that they can serve their customers to install the necessary equipment for using technology-based channels at an advantage. Keywords: Relationship marketing, technology-based service channels, relationship quality, consumer behaviour.


To study effect of furrow fertigation on amount of protein, yield and yield components of corn, a field experiment was conducted in Seed and Plant Improvement Institute of Karaj, Iran in the summer of 2012. The study design was a factorial design based on randomized complete block with 4 replication. First factor (N) includes three fertilizer levels of 60%, 80% and 100% recommended fertilizer value and the second factor (T) includes two split application fertilizer levels (four and three split application). The nitrogen required for the plant is provided by urea fertilizer and used along with water irrigation. Finally, these 6 treatments were compared with traditional fertilizer application method (Control). The results showed that treatment of 80% and 100% recommended fertilizer has not a significant difference with amount of protein. Therefore, 80% recommended fertilizer in four split application is recommended for increase of protein. The results in terms of yield of corn showed that 60% fertilizer in four split application has the most yield. In addition, the results showed that fertigation comparing method of surface fertilizer distribution increases yield and yield components. Therefore, fertigation is recommended as fertilizer management choice comparing traditional method of fertilizer distribution.


The simulation and discussion of five MPPT techniques for a PV system under various conditions of uniform and partial shading conditions (PSC) is presented. The techniques considered are hill climbing (HC), fuzzy logic control (FLC), perturbed extremum seeking control (PESC), firefly algorithm (FA), and cuckoo search algorithm (CS). Based on models previously stated in the literature, and inspired in a photovoltaic (PV) system in Cundinamarca, a comparative analysis is done based on the efficiency which measures performance in steady state, and the integral absolute error (IAE), which facilitate the analysis in both transient and steady state. Under uniform shading conditions fuzzy logic performs better than the other techniques under both mentioned criteria, followed by CS which shows a high efficiency but a slower convergence time. Also, PESC has shown a good performance, while being less complex than FLC. Under partial shading conditions cuckoo search demonstrates better performance in efficiency and convergence time than the firefly algorithm.


Feroseta priscus (Neuroptera: Mantispidae), a new genus and new species of mantidflies, is described from Dominican amber. Diagnostic characters of the new genus are: 1, The cubitus of the hindwing is parallel to the first anal vein and does not touch it; 2, the absence of a pterostigma in all wings; 3, the shape and pedicellated nature of the flagellomeres; 4, the extended tip of the terminal flagellomere; 5, the structure of the thorax; and 6, the elongated male ectoprocts.


Integrated water resource management (IWRM) is a response to current acknowledgement of the complexity and wickedness of water management. IWRM aims to enable appropriate responses via multi-party participation. Adaptive management—purposeful learning for improved action—is a useful tool for integrating water resource management. It provides a framework to enable participatory processes and social learning to contribute to changed policies and practices. However, the institutional constraints on moving to adaptive management (and hence IWRM) are many and deeply entrenched. The paper explores these constraints by considering the almost unconscious, and generally uncritical, reliance on 'projects' in natural resource management. Using examples from Australia, it reflects on the defining features of natural resource management 'projects' and critically considers these in relation to the conditions needed for adaptive management, social learning and IWRM. Projects, bounded in time and space and strongly tied to political and financial cycles, encourage short-term planning and action, not to mention risk avoidance and solidification of power differentials. Active reflection on the nature of projects provides a useful space to explore a possible clash between the normative idealistic and the critical realist perspectives of integrating water management.