A VHF microstrip patch antenna was developed to achieve a bandwidth of 45 MHz (300%) from 127 MHz to 172 MHz with dual-linear-polarization capability. This microstrip antenna uses foam substrates and dual stacked patches with capacitive probe feeds to achieve wide bandwidth. Four such capacitive feeds were used to achieve dual polarization with less than -20 dB of cross-polarization level. Twenty-four shorting pins were used on the lower patch to achieve acceptable isolation between the four feed probes. This antenna has a measured gain of 8.5 dB at 137 MHz and 10 dB at 162 MHz. By using the method of moments technique, multipath scattering patterns were calculated when the antenna is mounted on the outside of a Twin Otter aircraft.


Objective:To investigate the carrier rate of thalassemia gene in pregnant women with decreased mean corpuscular volume,direct the prenatal diagnosis in couples both carrying the same type of thalassemia gene,decrease the birth rate of intermedia or major thalassemia children.Methods:Pregnant women whose mean corpuscular volume lower than 79 fl were advised to detect thalassemia gene for themselves as well as their husbands.73 couples fulfilled gene detection including 3 kinds of α thalassemia deletion mutation gene,5 kinds of α thalassemia non-deletion mutation gene and 17 kinds of β thalassemia gene that were common in China.Results:Among 73 pregnant women,55 cases were found thalassemia,including 2 cases of HbH,27 cases of α-thalassemia 1,10 cases of α-thalassemia 2,15 cases ofβ-thalassemia heterozygote(including 1 case of HbE),1 case of α-thalassemia and β-thalassemia.Among 73 husbands,18 cases were found to be thalassemia gene carrier,consisting of 6 cases of α-thalassemia 1,7 cases of α-thalassemia 2,5 cases of β-thalassemia heterozygote(including 1 case of HbE).Ten couples were found to be both thalassemia gene carrier,7 couples carried the same group gene..Prenatal diagnosis were required in 5 couples excluding 2 couples carrying α-thalassemia 2.Conclusion:Carrier rate of thalassemia gene in pregnant women with lower MCV is very high.Gene detection for couples carrying the same kind of thalassemia gene directing for prenatal diagnosis can decrease the birth rate of intermedia and major thalassemia child.


Abstract Density function theory calculations of minimum energy structure of an oxygen molecule and oxygen atom bonded to the two dimensional molecules, C23NH12, coronene and C21NH14, pentacene doped with nitrogen, indicate the structures are at a minimum on the potential energy surface having no imaginary frequencies. Calculation of the bond dissociation energy (BDE) to remove an oxygen atom from nitrogen-doped pentacene to which is bonded O2, (C21NH14O2) shows it is less than that to dissociate O2. However, this is not the case for nitrogen-doped coronene. This suggests that nitrogen-doped pentacene could be an effective catalyst for the oxygen reduction reaction in fuel cells assuming it is O2 dissociation. It is also shown that O2H can bond to nitrogen-doped coronene and pentacene and that the BDE to remove OH is less than that to remove OH from O2H indicating that N-doped coronene and pentacene could also catalyse this reaction. The calculated adsorption energy for O2 and O2H on these molecules is negative indicating they can bond to N-doped coronene and pentacene.


Marketing compost to governmental entities for use on public landscapes, sports fields, playground facilities and road construction provides an option for exporting dairy manure out of the impaired North Bosque River watershed. Composts produced with dairy manure from that area tend to contain high levels of inorganic components (50 to 75%, mainly quartz sand and limestone fragments) and often fail to meet the pH and organic matter standards set by TX DOT and other users. Addition of high carbon amendments to finished composts is being employed as a means to adjust these parameters to meet the TxDOT standards. Four "low quality" compost products were amended with three high carbon by-products (peanut hulls, sawdust and wood chips) by physically mixing the amendments (10% and 30% v/v basis) with the composts. Significant differences between the four compost sources were noted for several parameters including organic matter, total N, C:N ratios and pH. Sampling dates (0 DAI and 30 DAI) also resulted in significant differences in organic matter; pH; total P, Ca, and Na; and the bioassay for cucumber seedling vigor, indicating variability within the compost products. Adding 10% and 30% high carbon amendments resulted in significantly higher organic matter levels when analyzed between compost sources but only the higher (30%) rates significantly increased organic matter contents across sources. With the exception of the 30% rate of peanut hulls which produced a significant decrease in pH and a significant increase in total N between compost sources, the organic amendments had no consistent effects on pH, N, P, Ca, Na, soluble salts or cucumber seedling vigor between or across compost sources. Results suggest that the physical mixing of high carbon amendments with low quality dairy manure compost can be used to increase organic matter content and alter C:N ratios but will have limited effects on pH, soluble salts, nutrients or cucumber seedling vigor.


Abstract The hemisphere lens-loaded Vivaldi antenna for the microwave imaging applications is designed and tested in this paper. The proposed antenna is designed to work in the wide frequency band of 1–14 GHz, and is fabricated on the FR-4 substrate. The directivity of the proposed Vivaldi antenna is enhanced using a hemispherical shape dielectric lens, which is fixed on the end-fire direction of the antenna. The proposed antenna is well suited for the microwave imaging applications because of the wide frequency range and high directivity. The design of the antenna is carried out using the CST microwave studio, and various parameters such as the return loss, the radiation pattern, the directivity, and input impedance are optimized. The maximum improvement of 4.19 dB in the directivity is observed with the designed hemisphere lens. The antenna design is validated by fabricating and testing it in an anechoic environment. Finally, the designed antenna is utilized to establish a setup for measuring the scattering coefficients of various objects and structures in the frequency band of 1–14 GHz. The two-dimensional (2D) microwave images of these objects are successfully obtained in terms of the measured wide band scattering data using a novel time domain inverse scattering approach, which shows the applicability of the proposed antenna.


A novel nanocomposite resist is presented based on AgNWs dispersed in poly(methyl methacrylate). It is shown that this nanocomposite resist displays sheet resistances below 10 Ω sq−1 for concentrations of AgNWs higher than 4 % wt and can be used for a wide range of microfabrication techniques. The resist can act as a conductive ink that cures at room temperature, form thin films with low sheet resistances, and be used in fast replication methods derived from soft lithography. Furthermore, it can be applied for nano-scale fabrication via electron beam lithography (EBL) on different substrates, including flexible and insulating materials, providing a straightforward method to avoid charging effects. This, being the first report about a nanocomposite resist based on AgNWs for EBL, describes a simple procedure to account for suspended nanowires, forming bridges, nanocantilevers and more complex nanostructures. A wide range of opportunities opens for the single-step fabrication of electronic components in the nano and micro scale.


A concave bit grinding device comprises a grinding wheel mechanism, a grinding control device and an optical sensing device, wherein the grinding wheel mechanism includes a first grinding wheel and a second grinding wheel, the first grinding wheel and the second grinding wheel are positioned side by side in the way that the grinding edges of the both form a alternate angle when seen from lateral side, the grinding control device is characterized in that the grinding edges of the first grinding wheel and the second grinding wheel are provided on the front with an automotive flat base which is used for controlling the charge-in and the discharge of the concave bit and provided with a sliding seat, the sliding seat is used for controlling the grinding amount of feed of the concave bit and provided with a fixing letter and a work-piece bearing, the fixing letter is used for clipping the stalk portion of the concave bit and capable of driving the concave bit to rotate quantitatively, and the work-piece bearing is used for supporting the flight portion of the concave bit. The concave bit grinding device is capable of keeping the concave bit at the horizontal position. The optical sensing device is provided on the outboard of the first grinding wheel and the second grinding wheel provided with an image visualizer of which the eyepiece and the light projector are positioned to be capable of shooting the end-face image, the lateral image or the both of the drill edge of the drill bit and of providing the data of the image area of the real drill edge for the computer to analyze and check the data of the grinding quality.


Monomeric compound comprising: at least one functional group polymerizable per molecule, and at least one bicycloheptenyl polyether group according to structure (I): - R13-R12-R11 (I) where R11 is a Nopol derived bicycloheptenyl, the group being able to Bicycloheptenyl polyether is optionally substituted on one or more of the carbon atoms of the ring with one or two (C1-C6) alkyl groups per carbon atom of the ring, R12 is not present or is a bivalent linking group, and R13 is a polyether group bivalent.


BepiColombo, the forthcoming ESA (cornerstone) mission to Mercury, will include a comprehensive set of experiments - called Radio Science Experiments (RSE) in order to measure the gravitational field and rotational state of the planet and its rotation and to perform precise tests of Einstein's theory of general relativity versus other metric theories of gravity. Among the onboard instruments, a fundamental role in the RSE will be played by ISA (Italian Spring Accelerometer). This paper is devoted to the description of the main on-ground ISA internal actuators calibration and the obtained accuracy which is necessary to guarantee the accelerometer performance in order to reach the very ambitious objectives of RSE.


Up to 20% of patients are not satisfied with the outcome following total knee replacement (TKR), but little is known about the predictors of this dissatisfaction. This study investigated the pre- and post-operative predictors of dissatisfaction in a large cohort of patients undergoing TKR. We assessed 1217 consecutive patients undergoing TKR between 2006 and 2008 both preoperatively and six months after surgery, using the Short-form (SF)-12 health questionnaire and the Oxford Knee Score. Detailed co-morbidity information was also gathered. Satisfaction was measured at one year and 18.6% (226 of 1217) of patients were unsure or dissatisfied with their replacement, 81.4% (911 of 1217) were satisfied or very satisfied. Multivariate regression analysis was performed to identify independent predictors of dissatisfaction. Significant (p Satisfaction following TKR is multifactorial. Managing patient expectations and mental health may reduce dissatisfaction rates. However, the most significant predictor of dissatisfaction is a painful total knee replacement.


Water extracts of leaves prepared by three different extraction Psidium guajava methods were compared with respect to their anti-infective activity against and in the nematode host Pseudomonas aeruginosa Staphylococcus aureus . The water extract prepared by Microwave Assisted Caenorhabditis elegans Extraction method was found to have better anti-infective activity, and its activity was further compared with hydroalcoholic extract prepared using the same extraction method against five different pathogenic bacteria. Both these extracts could attenuate virulence of , , P. aeruginosa S. aureus Serratia , and , towards marcescens Chromobacterium violaceum C. elegans. Anti-infective efficacy of leaf extract seems partly to stem from its P. guajava quorum-modulatory property, as it could modulate production of quorum sensing-regulated pigments in all the susceptible bacteria.


We study a generalization of additive bases into a planar setting. A planar additive basis is a set of non-negative integer pairs whose vector sumset covers a given rectangle. Such bases find applications in active sensor arrays used in, for example, radar and medical imaging. The problem of minimizing the basis cardinality has not been addressed before.
We propose two algorithms for finding the minimal bases of small rectangles: one in the setting where the basis elements can be anywhere in the rectangle, and another in the restricted setting, where the elements are confined to the lower left quadrant. We present numerical results from such searches, including the minimal cardinalities for all rectangles up to $[0,11]\times[0,11]$, and up to $[0,46]\times[0,46]$ in the restricted setting. We also prove asymptotic upper and lower bounds on the minimal basis cardinality for large rectangles.


Quantum mechanics is not the unique no-signaling theory which is endowed with stronger-than-classical correlations, and there exists a broad class of no-signaling theories allowing even stronger-than-quantum correlations. The principle of information causality has been suggested to distinguish quantum theory from these nonphysical theories, together with an elegant information-theoretic proof of the quantum bound of two-particle correlations. In this work, we extend this to genuine N-particle correlations that cannot be reduced to mixtures of states in which a smaller number of particles are entangled. We first express Svetlichny's inequality in terms of multipartite no-signaling boxes, then prove that the strongest genuine multipartite correlations lead to the maximal violation of information causality. The maximal genuine multipartite correlations under the constraint of information causality is found to be equal to the quantum mechanical bound. This result consolidates information causality as a physical principle defining the possible correlations allowed by nature, and provides intriguing insights into the limits of genuine multipartite correlations in quantum theory.


In view of the troubles in auxiliary power supply for multiple units passing neutral section,the causes to the troubles are analyzed,the method of solution is given out.The troubles in the auxiliary power supply device caused by network voltage distortion have been basically removed.


Introduction: The incidence of the morbidly-adherent placenta, previously thought to be very uncommon, is rising in contemporary obstetrical practice and obstetricians must be cognizant of this. Massive obstetric haemorrhage, particularly at delivery, is the principal clinical problem and the condition is associated with a risk of maternal and perinatal mortality of upto 10%. Imaging plays an important role in the antenatal detection of this condition. Objective: To determine the diagnostic accuracy of Doppler ultrasound for antenatal detection of morbidly adherent placenta in patients presenting with placenta previa major degree taking surgical evidence as gold standard. Study Design: Cross sectional study Settings: The study was conducted in Obstetric and gynaecology unit 1, Sir Ganga Ram Hospital Lahore Duration of Study: Jan 2013 to June 2013 Results: Frequency of morbidly adherent placenta is females having placenta previa revealed in 14.38%(n=23),accuracy of Doppler ultrasound for antenatal detection of morbidly adherent placenta in patients presenting with placenta previa major degree taking surgical evidence as gold standard reveals 12.5%(n=3)true positive ,1.25%(n=2) false positive,1.88%(n=3) false negative and 84.38%(n=135) as true negative. Whereas specificity, sensitivity, positive predictive value ,negative predictive value and diagnostic accuracy was calculated as 86.96%,98.54%,90.91%,97.83% and 98.13% respectively. Conclusion: It is concluded that Doppler ultrasound for antenatal detection of morbidly adherent placenta in patients presenting with placenta previa major degree taking surgical evidence as gold standard is an accurate method of diagnosis.


total motor score were signi fi cant predictors of motor score recovery. However, no variables were prognostic when utilizing AIS conversion as the endpoint. CONCLUSIONS: AIS conversion underestimates true degree of functional improvement following SCI. Changes in full motor score is a more robust outcome metric in the evaluation of factors prognostic of neurological recovery following injury.


Abstract
Introduction
This PhD thesis is focused on analysing one of the concepts that has been used in the interpretation of several national and international Palaeolithic, Neolithic and Copper Age archaeological contexts, which is the notion of "place of aggregation". In general, this analytical category has not been clearly defined. Thus, it has been ambiguously used to explain the same kind of archaeological contexts, even in the same geographic areas. From ritual places of congregation of societies with strong mobility patterns to stable settlements based on permanent farming production, the idea of "aggregation sites" has been used to explain human past. Therefore, one of the objectives is to critically examine the different definitions of what are considered social aggregation processes in Prehistory. Also, it aims to provide new ideas for a clearer conceptualisation of archaeological sites that may be interpreted as aggregation sites, specifically for those that can be interpreted as gathering places. Finally, an archaeological phenomenon that often has been interpreted under this notion is discussed.
Methodological development
Methodologically, the thesis develops historical, ethnographic and archaeological tools. The results of the different analyses are presented in three main parts: In the first part, the research questions and objectives are presented and explained in detail. A profound literature review of the use of the concept of social aggregation in Archaeology and Anthropology is carried out to identify what the ideas behind this category were and are, according with the state of the art.
The second part presents the theoretical framework and two ethnographic cases. They are analysed in depth under a post-colonial and ethnoarchaeological perspective. Paradigmatic and long-lasting gathering places are studied through fieldworks in Chile (Wallmapu) among the Mapuche people, and in New Zealand (Aotearoa) among Māori people. A definition of "gathering place" – one of the senses of aggregation sites - is proposed after the theoretical and ethnographic discussion. In the third part, the archaeological phenomenon is discussed as regard of the previous analysis. The Iberian Copper Age ditched enclosures are presented and examined considering both theory and material culture information. The research is then focused on two case studies, Perdigoes site (Reguengos de Monsaraz, Portugal) and Marroquies Bajos site (Jaen, Spain). Both of them provide new and updated information. This research has contributed to their knowledge with excavations campaigns and new analyses focused on the formation processes of complex stratigraphic sequences and human mobility study. Results are compared to the notions of aggregation and gathering.
Conclusions
The final discussion of results and conclusions of the thesis are presented concerning the main interests of the PhD research, which are: the debate on what is considered "social aggregation" and "gathering place"; the critical use of data from ethnographic sources and fieldwork carried out among contemporary populations; the discussion of the functionality and communal processes behind the construction of ditched enclosures; and the suitability of these concepts to the interpretation of Iberian ditched enclosures. Finally, it is concluded that there are different levels of places of aggregation study. Consequently, a specific methodology of analysis of archaeological gathering places is proposed, and it is suggested a different perspective of diched enclosures study, in order to come to understand their complex material record throughout time.
Bibliografia basica.
ALBERTI, B.; MARSHALL, Y. (2009). "Animating Archaeology: Local Theories and Conceptually Open-ended Methodologies". Cambridge Archaeological Journal, 19, pp. 344-356.
ANDERSON, A.; BINNEY, J.Y HARRIS, A. (2014). Tangata Whenua. An Illustrate History. Briget Williams Books. Auckland.
BENGOA, J. (2000). Historia del pueblo mapuche. (Siglo XIX y XX. LOM Santiago de Chile.
BRONK RAMSEY, C. (1995). "Radiocarbon calibration and analysis of strtigraphy: the Oxcal program". Radiocarbon 37 (2), pp. 42-430.
BURGUESS, C.; TOPPING, P.; MORDANT, C.; MADDISON, M. (eds.) (1988). Enclosures and Defences in the Neolithic of Western Europe, Part. 1. BAR International Series 403 (i). Archaeopress.Oxford.
DIAZ-DEL-RIO, P. (2008). "El contexto social de las agregaciones de poblacion durante el Calcolitico Peninsular". En Valera, A.C. (ed.) A ideia de recinto e a sua expressaon iberica na Pre-Historia Recente. Era Arqueologia 8, pp. 128-137.
DIAZ-ZORITA BONILLA, M. (2017): The Copper Age in south-west Spain: a bioarchaeological approach to prehistoric social organisation. British Archaeological Reports International Series S2840, British Archaeological Reports, Oxford.
DILLEHAY, T. D. (2007). Monuments, Empires, and Resistance. The Araucanian Polity and Ritual Narratives. Cambridge University Press. Cambridge.
JIMENEZ-JAIMEZ, V. (2015). "The Unsuspected Circles. On the Late Recognition of Southern Iberian Neolithic and Chalcolithic Ditched Enclosures". Proceedings of the Prehistoric Society, 81, pp. 179–198.
LATOUR, B. (2005).Reensamblar lo social. Una introduccion a la teoria del actor-red. Manantial. Buenos Aires.
MARQUEZ ROMERO, J.E y JIMENEZ JAIMEZ, V. (2010). Recintos de Fosos. Genealogia y significado de una tradicion en la Prehistoria del suroeste de la Peninsula Iberica (IV-III milenios AC), Servicio de Publicaciones e Intercambio Cientifico. Universidad de Malaga, Malaga.
VALERA, A.C. (2013a). "Recintos de Fossos da Pre-Historia Recente em Portugal. Investigacao, discursos, salvaguarda e divulgacao."En Grandes Projecto da Arqueologia Portuguesa, Al-madan, II Serie 18, pp. 93-110.
ZAFRA DE LA TORRE, N.; CASTRO LOPEZ, M.; HORNOS MATA, F. (2003). "Sucesion y simultaneidad en un gran asentamiento: la cronologia de la macro-aldea de Marroquies Bajos, Jaen. c. 2500-2000 cal ANE". Trabajos de Prehistoria, 60(2), pp. 79–90.


Osteoclasts, multinucleated bone‐resorbing cells, are specialized cells derived from the monocyte/macrophage lineage. Therefore, it is essential for mononuclear precursors to find a fusion partner during its differentiation. Our previous study showed an important role of cell communication via Mac‐1 (CD11b/CD18) during osteoclastogenesis. However, the counter receptor of Mac‐1 was still unknown. Flow cytometric analysis showed that bone marrow‐derived mononuclear cells, used as osteoclast precursors, expressed intercellular adhesion molecule‐1 and ‐2. Quantitative RT‐PCR analysis revealed that expression level of ICAM‐2 was higher than that of ICAM‐1 in bone marrow cells. The osteoclastogenesis induced by receptor activator of NF‐kappaB ligand (RANKL) was inhibited by anti‐ICAM‐2 neutralizing antibody but not by anti‐ICAM‐1 neutralizing antibody. The inhibitory effect of anti‐ICAM‐2 antibody on osteoclastogenesis was enhanced by simultaneous treatment of anti‐CD11b neutralizing antibody. Furthermore, osteoclastogenesis induced by tumor necrosis factor α (TNFα) was also inhibited by anti‐ICAM‐2 neutralizing antibody. The involvement of lymphocytes in osteoclastogenesis was excluded, because anti‐ICAM‐2 antibody inhibited osteoclastogenesis using bone marrow‐derived cells from immunodeficiency mice. Immunocytochemical staining demonstrated colocalization of ICAM‐2 and Mac‐1 during osteoclastogenesis; however, Mac‐1 immunoreactivity was lost in differentiated multinucleated osteoclast. These results suggest the important role of ICAM‐2/Mac‐1 binding in osteoclastogenesis induced by either RANKL or TNFα.


In this paper a thermal concentrating design method was proposed based on the concept of generating function without knowing the needed coordinate transformation beforehand. The thermal harvesting performance was quantitatively characterized by heat concentrating efficiency and external temperature perturbation. Nonlinear transformations of different forms were employed to design high order thermal concentrators, and corresponding harvesting performances were investigated by numerical simulations. The numerical results shows that the form of coordinate transformation directly influences the distributions of heat flows inside the concentrator, consequently, influences the thermal harvesting behaviors significantly. The concentrating performance can be actively controlled and optimized by changing the form of coordinate transformations. The analysis in this paper offers a beneficial method to flexibly tune the harvesting performance of the thermal concentrator according to the requirements of practical applications.In this paper a thermal concentrating design method was proposed based on the concept of generating function without knowing the needed coordinate transformation beforehand. The thermal harvesting performance was quantitatively characterized by heat concentrating efficiency and external temperature perturbation. Nonlinear transformations of different forms were employed to design high order thermal concentrators, and corresponding harvesting performances were investigated by numerical simulations. The numerical results shows that the form of coordinate transformation directly influences the distributions of heat flows inside the concentrator, consequently, influences the thermal harvesting behaviors significantly. The concentrating performance can be actively controlled and optimized by changing the form of coordinate transformations. The analysis in this paper offers a beneficial method to flexibly tune the harvesting performance of the thermal concentrator according to the requirements of practical appl...


The 2010 UK coalition government set itself four priorities for tax policymaking: to make the UK tax system more competitive, simpler, greener and fairer. This study uses data from tax information and impact notes, a new application of impact assessment methodology, to assess progress towards these goals. Findings show in 2010–2013 a third of tax changes did not contribute to any of the goals, a quarter related to fairness and a fifth to simplification. Whilst competitiveness was poorly served in number of measures, it was significant in terms of tax foregone as a result, and external assessments of UK competitiveness mean it could be argued the objective has been achieved. Green measures were fewer than 7% of any fiscal event and the green objective has been quietly dropped. The article goes on to examine the differing understanding of tax objectives between tax professionals and the wider public and argues that othering non-professionals as 'tax prats' should cease in favour of inclusion of 'citizen stakeholders'.


A simple method which gives the main effect of the ions on the surface potential of metals is developed. This method is applied to studying self consistently the surface potential and the relaxation of ionic planes. The surface potential of the Na (100) face as well as the ionic relaxation of Al (111) and (110) faces have been obtained and compared with experimental data and other theoretical results.


GaAsPN semiconductors are promising material for the elaboration of high efficiencies tandem solar cells on silicon substrates. GaAsPN diluted nitride alloy is studied as the top junction material due to its perfect lattice matching with the Si substrate and its ideal bandgap energy allowing a perfect current matching with the Si bottom cell. We review our recent progress in materials development of the GaAsPN alloy and our recent studies of all the different building blocks toward the elaboration of a PIN solar cell. A lattice matched (with a GaP(001) substrate) 100 nm-thick GaAsPN alloy has been grown by MBE. After a post-growth annealing step, this alloy displays a strong absorption around 1.8-1.9 eV eV, and efficient photoluminescence at room temperature suitable for the elaboration of the targeted solar cell top junction. An early stage GaAsPN PIN solar cell prototype have been grown on a GaP (001) substrate. The quantum efficiency and the I-V curve show that carriers have been extracted from the GaAsPN alloy absorber, with an open-circuit voltage around 1 eV, while however displaying a low short circuit current meaning that the GaAsPN structural properties needs an optimization. Considering all the pathways for improvement, the >2% efficiency obtained under AM1.5G is however promising, therefore validating our approach for obtaining a lattice-matched dual junction solar cell on silicon substrate. This work was supported by the French ANR, project MENHIRS (grant N°ANR-2011-PRGE-007-0).


A prototype dye laser flow loop was constructed to flow test large power amplifiers in Building 169. The flow loop is designed to operate at supply pressures up to 900 psig and flow rates up to 250 GPM. During the initial startup of the flow loop experimental measurements were made to evaluate component and system performance. Three candidate dye flow loop pumps and three different pulsation dampeners were tested.


JCE QBank is an online collection of questions (and sometimes answers) that can be used in a variety of settings. The collection currently can be divided into four categories: ConcepTests, Conceptu...


This chapter focuses on the attempt to 'sell' rearmament – which the National Government increasingly believed was necessary – to the public through a series of White Papers outlining its position on defence in 1935 and 1936. The 1935 general election, the League of Nations Peace Ballot, the Italian invasion of Abyssinia, and the appointment of further subcommittees on defence requirements (and their effects on rearmament) are all discussed. The latter part of the chapter discusses Lithgow's business empire, part of which was built on information he received through his work as a government advisor.


Objective:To study the effect of exercise(dance) on the state of an illness, emotion and sympathetic nervous system function in patients with coronary artery disease(CAD).Methods:Seventy-seven CAD patients (exercise group) participated the exercise in square from September 2003 to September 2005(at least 5d every week,60~120 min every time;6 months every period of treatment).The following indices were measured before and after exercise:①State of an illness and electrocariogram(ECG);②Scores of mentation(total score of SCL-90 and score of every factor);③Heart rate variability(area of time and frequency).The 48 CAD patients composed control group,who only accepted medication therapy.Results:(1)Indices of state of an illness and ECG in exercise group were markedly better than before therapy(P0.05~0.01),meanwhile some of indices were better than those of control groups(P0.05);(2)Scores of emotion in exercise group were lower than before therapy, and part indices were lower than those of control group(P0.05~0.01);(3)Effect of HRV were similar with scores of emotion.Conclusion:Exercise in square may obviously improve the state of an illness,emotion and sympathetic nervous system function in patients with coronary artery disease.


Research prerequisites: Insufficient scientific knowledge of this issue dictates the advisability of considering and studying this topic. For the first time, the article highlights the legal aspects associated with the use of methods of struggle, special means, and military weapons by employees of special-purpose units of the criminal-executive (penitentiary) system of Russia. The paper states that only for the commission of criminal offences, it is possible to use military weapons by special forces units of the Federal Penitentiary Service and special escorting divisions of the criminalexecutive system of the Russian Federation. Purpose of the research: to investigate the law enforcement activities of the penitentiary special forces associated with the use of coercive measures including for criminal offences. Methods: when considering the essence of coercive measures in the law enforcement activities of special-purpose units, the article used the dialectical method. To formulate the conditions for the correct (legal) use of weapons in law enforcement directly by employees of special-purpose units of the Russian penitentiary system, systematized methods were used. The empirical method was used when interviewing special forces officers in the investigated activities. Results and novelty: the scientific result of this article is the first formulated many components aimed at improving the measures of coercion. In particular, the grounds for the correct use of methods of struggle, special means, and military weapons are proposed. The article identifies situations (circumstances) associated with a real threat to the life and health of a special-purpose employee. The negative and positive aspects associated with the use of coercive measures are emphasized.


Background Post-remission therapies for patients with AML such as high-dose cytarabine (HiDAC) and allogeneic stem cell transplant (alloSCT) have led to improved outcomes for younger patients, but disease recurrence remains prevalent with ~40% 5-year OS. CD33 is a cell surface receptor expressed in ~90% of AML, representing a promising target for therapy. Vadastuximab talirine (33A) is a CD33-directed antibody conjugated to 2 molecules of a pyrrolobenzodiazepine (PBD) dimer. Methods This phase 1b dose-escalation study (NCT02326584) evaluates the safety and anti-leukemic activity of 33A in combination with consolidation therapy (HiDAC) or as a single agent for maintenance therapy. AML patients (ECOG status 0-1) must be in 1st remission (CR or CRi) after standard induction therapy and be able to receive HiDAC (consolidation cohort) or be in 1st remission and have completed planned post-remission therapies, either chemotherapy and/or alloSCT (maintenance cohort). For maintenance post-alloSCT, patients were between Day 60 and 100 post-transplant without significant GVHD. Prior to HiDAC administration (3 gm/m2 q12h Day 1, 3, 5), 33A is given on Day 1 for up to 4 cycles (28-day cycle). For maintenance therapy, 33A is given as a single agent on Day 1 for up to 8 cycles (6-wk cycle). Results Consolidation cohort: 21 patients (57% male) with a median age of 52 years (range, 21-64) were treated with 5, 10, or 20 mcg/kg of 33A with HiDAC. Patients received a median of 2 cycles (range, 1-4). As anticipated, all patients experienced Grade 4 myelosuppression. At 20 mcg/kg, 1 DLT (lack of recovery of platelets [25K] and/or ANC [500] by Day 42) occurred in Cycle 1. At 10 mcg/kg, no DLTs were observed but delay of subsequent cycles of treatment occurred in 4 of 10 patients, primarily due to thrombocytopenia. No DLTs were observed in the 8 patients treated at 5 mcg/kg and 1 non-hematologic-related dose delay was reported (otitis externa). Non-hematologic treatment-emergent adverse events (AE) in ≥25% of patients regardless of relationship included nausea (38%) and fatigue (33%). No infusion-related reactions (IRRs) or events of veno-occlusive disease were reported. The 30- and 60-day mortality rates were 0%. Of the 19 efficacy evaluable patients, 15 (79%) have maintained remission, 18 patients are alive and 3 patients (14%) remain on treatment. Reasons for treatment discontinuation were completion of planned consolidation therapy (38%), AE (thrombocytopenia, 14%), leukemic relapse (5%), and other non-AE (29%). Nine patients (43%) went on to receive an alloSCT. Maintenance cohort: 22 patients (41% male) with a median age of 45.5 years (range, 23-71) have been treated with 5 mcg/kg of 33A. Patients were a median of 6.2 months from diagnosis (range, 3.4-21.5); 12 patients completed chemotherapy-based treatment alone and 10 patients completed standard chemotherapy with an alloSCT in 1st remission. Patients received a median of 3 cycles (range, 1-6); no DLTs were reported. AEs reported in ≥15% of patients were fatigue (41%), neutropenia (41% [36% ≥G3]), nausea (36%), thrombocytopenia (36% [27% ≥G3]), diarrhea, dyspnea, headache, and vomiting (18% each); no IRRs were observed. Of the 20 efficacy evaluable patients, 15 (75%) have maintained remission. Reasons for treatment discontinuation were AEs (41%, primarily myelosuppression), leukemic relapse (14%), completion of planned therapy (9%), and other non-AE reasons (19%); 4 patients (18%) remain on treatment. Median OS is not yet reached and 19 patients are alive. Pharmacokinetic data in patients receiving post-remission therapy with 33A demonstrate that exposure appears to be greater than in patients with active disease, possibly due to a decrease in target-mediated disposition. Conclusions 33A can be safely administered in combination with HiDAC and as monotherapy in the post-remission setting. In combination with HiDAC, non-hematologic toxicities of 33A were consistent with effects reported with HiDAC alone. As a single agent, 33A administered as maintenance post-chemotherapy and/or alloSCT results in predictable on-target myelosuppression, with mild non-hematologic adverse effects. Disclosures Yang: Seattle Genetics: Research Funding. Ravandi: Seattle Genetics: Consultancy, Honoraria, Research Funding; BMS: Research Funding. Advani: Seattle Genetics: Consultancy, Research Funding. Walter: Emergent Biosolutions: Consultancy; Seattle Genetics: Research Funding; CSL Behring: Research Funding; Celator Pharmaceuticals: Research Funding; Amgen: Research Funding; Abbvie: Research Funding; Pfizer: Consultancy; Amphivena Therapeutics, Inc.: Consultancy, Research Funding; Astra-Zeneca: Consultancy; Covagen AG: Consultancy; Agios: Consultancy; Arog: Research Funding. Faderl: Seattle Genetics: Research Funding; Pfizer: Research Funding; Astellas: Research Funding; Celator Pharmaceuticals: Research Funding; BMS: Research Funding; Ambit Bioscience: Research Funding; Karyopharm: Consultancy, Research Funding; Celgene: Consultancy, Research Funding; JW Pharma: Consultancy; Amgen: Speakers Bureau. Stein: Seattle Genetics: Research Funding; Amgen: Consultancy, Research Funding, Speakers Bureau; Stemline Therapeutics: Consultancy, Research Funding; Argios: Research Funding; Celgene: Research Funding. Erba: Celgene: Consultancy, Speakers Bureau; Amgen: Consultancy, Research Funding; Agios: Research Funding; Pfizer: Consultancy; Novartis: Consultancy, Speakers Bureau; Juno: Research Funding; Jannsen: Consultancy, Research Funding; Ariad: Consultancy; Millennium Pharmaceuticals, Inc.: Research Funding; Astellas: Research Funding; Incyte: Consultancy, DSMB, Speakers Bureau; Seattle Genetics: Consultancy, Research Funding; Gylcomimetics: Other: DSMB; Daiichi Sankyo: Consultancy; Sunesis: Consultancy; Celator: Research Funding. Fathi: Agios Pharmaceuticals: Other: Advisory Board participation; Seattle Genetics: Consultancy, Other: Advisory Board participation, Research Funding; Merck: Other: Advisory Board participation; Celgene: Consultancy, Research Funding; Bexalata: Other: Advisory Board participation. Levy: Amgen: Speakers Bureau; Jansen: Speakers Bureau; Millennium: Speakers Bureau; Seattle Genetics: Research Funding. Wood: Pfizer: Honoraria, Other: Laboratory Services Agreement; Amgen: Honoraria, Other: Laboratory Services Agreement; Juno: Other: Laboratory Services Agreement; Seattle Genetics: Honoraria, Other: Laboratory Services Agreement. Feldman: Seattle Genetics: Employment, Equity Ownership. Voellinger: Seattle Genetics: Employment, Equity Ownership.


In this paper, a combination of adaptive control and variable structure control methodology is proposed to solve the general fast time-varying plants with totally unstructured parameters. We show that the control scheme will work only under the assumptions of known order, relative degree, high frequency gain sign and minimum-phase property. In contrast to the conventional approaches where the variable structure design is applied mainly to the adaptation of some traditional parameters /spl Theta/ by using the knowledge of unknown bounds on control parameters, a new adaptation scheme for control parameters incorporating the variable structure concept is given. Owing to this new scheme, we forsake the standard requirement of the upper bounds on some unknown parameters, which is frequently adopted in the field of robust linear MRAC using variable structure design. It is shown that without any persistent excitation, the tracking error will converge to zero in finite time for relative degree one plants and to a small residual set exponentially (whose size depends on a design parameter) for plants with any higher relative degree.<<ETX>>


4th Workshop on ICT Uses in Warfare and the Safeguarding of Peace, Protea Hotel Balalaika, Sandton, South Africa, 16 August 2012


Pemphigus vulgaris is one of the major autoimmune bullous diseases which include pemphigus vulgaris, bullous pemphigoid, epidermolysis bullosa acquisita, linear IgA dermatosis, and many more new entities. The diagnosis of pemphigus vulgaris depends on clinical, histological and immunological criteria. Immunoblotting is a newly developed technique used to detect the specific antigens of these autoimmune bullous diseases. In this study, we successfully detected the anti-desmogleins autoantibodies from sera of five well-documented pemphigus vulgaris patients by using immunoblotting of cultured human keratinocyte cell extracts. Sera from four of these patients reacted with the 130 kDa desmoglein (Dsg) 3 protein band, one reacted with both 130 kDa and 160 kDa protein bands. We recommend immunoblotting should be used together with direct immunofluorescence and indirect immunofluorescence for the better diagnosis and classification of autoimmune bullous diseases.


The present study sought to provide an economic alternative to the inhabitants of the Pacto parish, as an initiative for production, postharvest optimization and industrialization of the local fruit growing area, also considering the tourist potential of the area, where wine tourism represents an opportunity for the area. The aim was to find the technical viability for the elaboration of wine from naranjilla. The applied research approach was mixed, and an exhaustive literature review was made on the winemaking techniques. The test evaluated number of sugars in the must (18, 21 and 24 ◦ Brix), addition of water (4:1) (Ma) and whole must (Mo). Yield, fermentation time, organoleptic properties of the final product (color, smell and flavor) were determined using a 5-point hedonic scale and physicochemical characteristics of wines with better acceptance. Commercial Saccharomyces cerevisiae was used as inoculum. The average yield for Ma was 70.6% w/w and Mo 45.0% w/w, fermentation was observed up to 288 hours. The addition of water adversely affected the taste; however, the general organoleptic evaluation had a weighting between 3 and 4 out of 5 points. Wines with the best acceptance were Mo24 and Ma21, adhering to the requirements of the Ecuadorian Technical Standard for fruit wine, characterized as semi-sweet. It is necessary to work on the improvement and transfer of the established technical process, especially to obtain higher yields, decrease acidity and incorporate new studies with tropical fruits for the benefit of agriculture, gastronomy, tourism and local development.


Objective This paper is to present the survey data regarding the social behavior of friends making associated with hearing-impaired students at junior high schools for the deaf. Methods 118 students from Shanghai Junior High School for the Deaf were surveyed on the range, activities and mentality of friends making through interviews. The data were compared with those of normal students. Results Deaf students depended largely on their educational settings, their peers and families to make friends. The lack of social interactive experiences and underdeveloped social abilities intertwine with each other, compounding their difficulties in making friends. Conclusion It is suggested to improve the peer relationships and social adaptability of hearing-impaired students from the aspects of friendship conception and interaction ability.


Abstract : This study explores the Future Tactical Truck System (FTTS) as it applies to the sustainment distribution system on the future battlefield. Objective Force logistics on the battlefield is required by the Objective Force Concept White Paper to be sustainable, trainable, versatile, responsive, survivable and agile. The FTTS is scheduled to be the primary transport vehicle that would enable the OF sustainment distribution system. The FTTS, with movement tracking system (MTS) and embedded radio frequency (RF-Tag) technology will improve motor transport operations and sustainment. The primary application of these technologies alone, in and of themselves will not be enough to meet Objective Force requirements. Changes to doctrine, organization, training, leader development, materials, personnel and facilities (DOTLM-PF) have to be explored to maximize the effectiveness of the FTTS enabled sustainment distribution system in the Objective Force. To investigate and gauge the appropriate changes, analysis is needed to test viable concepts. This study explores four proven logistical concepts from top American corporations; Schneider Trucking Corporation's concepts for fleet management and maintenance management, Burlington Northern Sante Fe Railroad's concept for railcar management and Wal-Mart's concept for distribution management. These concepts are applied to a FTTS sustainment distribution model and analyzed through the prism of DOTLM-PF to gain insights on possible changes that meet the Objective Force requirements and maximize effectiveness of the system. Qualitative analysis is used to provide discovery, insight and understanding through the eye of the researcher.


Purpose – Physical comorbidities of alcohol misuse are common and result in frequent attendance to hospitals with estimated £3.5bn annual cost to the NHS in England. The purpose of this paper is to evaluate the effect of the hospital in-reach team of the Leeds Addiction Unit (LAU) in reducing hospital service utilization in people with alcohol dependence. Design/methodology/approach – This is a retrospective cohort study, with a mirror-image design. The authors included all patients who had wholly alcohol attributable admission(s) to Leeds Teaching NHS Hospitals Trust (LTHT) during a four-month period between January and April 2013 and received treatment from LAU. The primary outcome measures were changes in A and E attendance (A&E) attendances, number of hospital admissions and days spent in hospital between the three months before and after the LAU intervention. Findings – During the four-month period, there were 1,711 wholly alcohol attributable admissions related to 1,145 patients. LAU saw 265 patient...


Background: Immunological deficiencies, altered angiogenic activity, infiltrative potential and growth factors are plausible factors behind endometriosis. The aim of this study was to determine whether endometriosis interferes with the course or outcome of pregnancy. Study Design: In this matched case-control study, we analyzed obstetric outcome among 137 women with endometriosis and 137 controls matched as regards IVF procedures and parity who gave singleton births at Kuopio University Hospital between January 1994 and December 2000. In affected women, the diagnosis was histologically verified, whereas the controls were eligible for the study only if they had undergone laparoscopy/tomy in connection with tubal sterilization, or infertility unrelated to endometriosis. Results: No statistically significant differences were detected in reproductive risk factors in women with endometriosis, with the exception of mean maternal age (31.2 years in the cases vs. 34 years in the controls). The mean birth weight (±SD) among those delivering at term (>37 completed weeks) was 3,600 (±542) g in the control group and 3,547 (±456) g in the study group. Placental weight was comparable in both groups. Overall pregnancy characteristics and pregnancy outcome measures were similar in women affected by endometriosis when compared with the control group. Conclusions: Any potential negative effect of endometriosis on obstetric outcome was undetectable.


The effect of radiation on the evolution of the collagen fractions of granular tissue of the rat was studied. A delay in the increase of the soluble coilagen fractions, followed by a correspondingly poor formation of insoluble collagen, was detected. ft was concluded that such a phenomenon is related to the decreased collagenogenic capacity of the fibroblasts of the exposed area. (auth)


In an effort to protect citizens' right-to-health, the Supreme Court of India on April 8th ordered the government to make COVID-19 testing free in all private hospitals and labs. The Court's decision in Sudhi v. Union of India marked a significant step towards ensuring that all people, especially poor workers in the informal sector have access to necessary care. Five days later, however, after facing objections from private companies and the state, the Supreme Court reversed its previous order and made testing free for only those living below the poverty line, an obligation already mandated under the National Health Policy Scheme.This commentary suggests that judicial action should be strengthened, not hampered, in times of global health crisis. While no state has unlimited resources to ensure the protection of health, the judiciary should be emboldened to hold the state to account.


The effect of calcium infusion on serum levels of calcium and phosphorus and on the fractional excretion of phosphorus (Cp/Ccr) was studied in eight normal subjects and in 35 patients with


Burge, T. 1988. Individualism and self-knowledge. Journal of Philosophy 85: 649-63. Ebbs, G. 1996. Can we take our words at face value? Philosophy and Phenomenological Research 56: 499-530. Ebbs, G. 2001. Is scepticism about self-knowledge coherent? Philosophical Studies 105: 43-58. Ebbs, G. 2003. A puzzle about doubt. In New Essays on Semantic Externalism and Self-Knowledge, ed. S. Nuccetelli, 143-68. Cambridge, Mass.: MIT Press. Moran, R. 2001. Authority and Estrangement: an Essay on Self-Knowledge. Cambridge, Mass.: Harvard University Press. Putnam, H. 1988. Representation and Reality. Cambridge, Mass.: MIT Press. Shoemaker, S. 1988. On knowing one's own mind. Philosophical Perspectives 2: 183209. DIANA RAFFMAN


Background. Distal cerebral aneurysms are very rare. To date, there are very few publications on distal cerebral aneurysms and they are mostly limited to clinical case series.Aim. To analyze anatomical characteristics of distal cerebral aneurysms and surgical outcomes, as well as to identify risk factors for a poor outcome and develop a treatment algorithm on this basis; to determine the role of neuronavigation and revascularization in the surgical treatment of distal cerebral aneurysms.Materials and methods. We performed a retrospective analysis of surgical outcomes of 153 patients with distal cerebral aneurysms treated in N.V. Sklifosovsky Research Institute for Emergency Medicine (Moscow Healthcare Department) between January 1, 2000 and December 31, 2019.Results. Distal cerebral aneurysms were identified in 4.5 % cases of all cerebral aneurysms; 81.7 % of patients with distal cerebral aneurysms were admitted to the hospital with ruptured aneurysms. The most frequent locations of distal cerebral aneurysms were pericallosal and middle cerebral arteries. Distal cerebral aneurysms were usually small (77.5 %), had a wide neck (31.8 %), and fusiform structure (15.7 %). Aneurysm clipping was performed in 74.5 % cases; parent artery trapping, in 23.5 % of patients; revascularization, in 5.9 % of patients. The main risk factors for a poor outcome included aneurysm size and location, patient grade on the modified scale of the World Federation of Neurosurgical Societies (mWFNS), and presence of severe vasospasm.Conclusion. The developed surgical algorithm for distal cerebral aneurysms (based on the assessment of a poor outcome risk factors, the use of neuronavigation, arterial patency control, and revascularization) could improve surgical outcomes of patients with distal cerebral aneurysms.


I. COMPARISON OF SCHIZOPHRENIC PATIENTS BEFORE AND AFTER FRONTAL LOBOTOMY IN RECENT years there has been increasing interest in the physiological aspects of mental disease, with particular attention to the role of the autonomic nervous system. Experience with psychoneurotic illnesses, in which somatic disturbances are associated with emotional tension, has indicated that the autonomic nervous system serves as a connecting link between psychic activity, on the one hand, and visceral function, on the other. This view has been well summarized by Cobb. 1 The observation of physiological disturbances in the psychoses, particularly in schizophrenia, points to such a mechanism. Investigators have sought to place this relationship on a sounder foundation by demonstrating its neurophysiological basis. Since the anterior frontal areas of the cerebral cortex are regarded as the seat of higher psychic activity, it becomes important to investigate their influence on the autonomic nervous system. Until recently, the bulk of


Citation: Morani AC, Mubarak AA, Vining DJ, Bhosale PR. The New Screening Guidelines for Colonic Neoplasms in Patients with Cystic Fibrosis; Are They Enough?. Ann Clin Case Rep. 2017; 2: 1468. ISSN: 2474-1655 Copyright © 2017 Ajaykumar C. Morani. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Editorial Published: 17 Nov, 2017


Objective To study the epidemiological characteristics of hand-foot-mouth disease (HFMD) in Anxi county in 2010 for the disease control and prevention. Method The data from "Infectious Diseases Reporting Information System" was analyzed by SPSS18.0 package. Results In 2010, the county reported 823 HFMD cases, but no severe cases and deaths. The incidence rate was 25.87 per 100 000 and there was 1 outbreak. Most HFMD cases were reported by municipal medical institutions, accounting for 48.1%. The interval was 2.46 days from onset to diagnosis by hospitals. The epidemiological trend of HFMD was sporadic, the constituent ratios of Longjuan (13.78%) and Guanqiao(7.77%) were higher than other areas. The incidence rates of Futian(110.10 per 100 000) and Taozhou(58.08 per 100 000) were higher than others. The constituent ratio (0.4%)and incidence rate(3.83 per 100 000) of Lantian were the lowest than others.The male-to-female ratios of incidence rate were 2.41∶1, the main HFMD cases occurred in age of 0-3,accounting for 84.45%. The HFMD cases were mainly occurred in scattered children, accounting for 89.00%. HFMD cases were reported each month. The month with least cases was November and December, with most cases in September. There were two peaks of incidence happened in the periods of April to May and August to September. Conclusions Primary medical institutions should improve the ability of diagnosis and treatment of the disease. Peoples should improve the awareness of prevention and treatment. It is crucial to focus on key groups and areas for prevention and control of HFMD.


This article addresses the Arabic manuscript which dates back to the 14th century. The manuscript ref. No 49 preserved in the library collection of the Moscow State Institute of International Relations (University) was initially noted in 1994 by D. A. Morozov in his list of Arabic manuscripts preserved in Moscow, and it was the same scholar who three years later published a brief description of the manuscript. Without prejudice to the significance of the work thus undertaken, it might be fitting to point to a number of inconsistencies and errors, for some of them the author cannot be excused by any means. The manuscript consists of two works, copied in 1332 and 1335: al-Tadhkirah fi ilm al-hay'ah [Memoir on Astronomy] by Naṣīr alDīn al-Ṭūsī (d. 1274); and Muḥammad b. Dihqān's Commentaries on the first chapter of the Miftāḥ al-ʻulūm [Key of sciences] by Abū Bakr al-Sakkākī (d. 1229). The present study brought to light previously unexplored copies of mediaeval treatises on astronomy and Arabic grammar, which possess a high level of quality and reliability. We have also succeeded in clearing up several errors and inconsistencies which had found their way into the previous catalogues, including the reference book on bibliography by the German orientalist Carl Brockelmann. Authors and titles of the works included in the manuscript were identified successfully.


Sometimes damaged fans by the storm or hurricane have been reported in the air-conditioner industry. High-speed reverse rotating of the fan caused by the external force from strong winds, especially without-driving condition. In this paper, a numerical analysis procedure to evaluate the reliability of the high-speed reverse rotating fan in air-conditioner outdoor unit by ultimate exterior flow velocities is proposed. Information of the reverse RPM and pressure distributions of blade surfaces are determined from 3-dimensional CFD analysis method and link directly to the structural analysis method to evaluate the structural stability factors. In addition, the results of this procedure expect to be useful to evaluate the reliability of outdoor unit fan and the suitability of the installing condition for system.


Rhodnius prolixus, better known as the kissing bug, is a blood‐sucking insect that utilizes a nitric oxide‐carrying protein as a means to obtain its meal through vasodilation, slowing platelet aggregation and strong histamine binding. The bug stores this nitrophorin protein within its salivary glands at low pH and is activated once released into the victim's blood. At present, four nitrophorin proteins have been discovered and fully sequenced, having been labeled NP1‐NP4 in order of decreasing abundance. NP3 is the only one of the four proteins which has not yet been characterized by x‐ray crystallography. This study will focus specifically on NP3 by comparing its wild‐type and native forms. Thus far, both forms have been cloned and expressed in E. coli and purified with sonication, dialysis and column chromatography. Throughout this procedure, it has been found that, out of all four of the nitrophorin proteins, NP3 remains one of the more difficult to isolate. However, with the recent success in growths of the native and wild‐type forms, the lab remains hopeful that this breakthrough can lead to point mutations within the protein, as they have with the other three nitrophorins.


Onshore wind energy has enjoyed a stable period of development on a global scale. The technological advances, which had aided to decrease the energy cost and the right policy instruments put in place to support the installation of wind energy systems have contributed to the significant increase in the application of wind energy within the electricity supply systems. This research aims to outline the onshore wind resource assessment and power production by employing different numerical approaches. For this purpose, the climatic conditions and short-term meteorological data from two onshore case studies in the southern part of Iran were chosen and analyzed. Afterwards, a wide variety of wind characteristics were investigated. Furthermore, a measure correlate predict (MCP) analysis based on the variance ratio algorithm was performed to analyze the relationship between two candidate sites in terms of wind speed and direction. The last stage of the study investigated the evaluation of the power density of the studied meteorological sites by analyzing the world classification of wind power and then making future recommendations towards development of wind energy in the studied regions.


Many older paediatricians will have vivid memories of Carl-Gustaf Bergstrand, who was managing editor of Acta Paediatrica for more than two decades, from 1965 to 1992 (Fig. 1). In the early days of his editorship, he personalised the first contact between the author and the journal, which took place by correspondence and telephone at a time when all submissions were still in the form of paper manuscripts. The inflow was certainly lower than today, but still amounted to several hundred papers a year. This meant that the workload for a managing editor who did not have editorial assistants was considerable.


BACKGROUND: Blood component donations by apheresis has become more common in modern blood transfusion practices. However, apheresis donation still remains less common in China. This study describes the demographic profile and transfusion‐transmissible infection (TTI) prevalence among donors making apheresis platelet (AP) donations compared to those making whole blood (WB) donations and the differences among five geographically diverse blood centers in China.


Abstract : The research presented in this thesis was composed of three parts. In the first part, the kinetics of the redox mediation between the azure dyes and the enzyme glucose oxidase was investigated. Electrochemical studies showed that azure dyes were fast mediators when dissolved in aqueous solutions. In the second part, the covalent immobilization of azure dyes in the biopolymeric matrix of chitosan was explored in order to design a reagentless glucose biosensor. These investigations indicated that the length of the tethering molecule was a crucial parameter, which controlled the mediation efficiency in the biosensor. The third part of this work was devoted to the preparation and characterization of a carbon paste-based electrochemical biosensor for glucose. The paste was modified with an azure eosinate mediator and glucose oxidase, and its analytical performance was tested under the conditions of diffusional and convective mass transport.


[1] The influence of bottom topography and the parameterization of subgrid-scale mixing upon the steady state circulation in a cold water bottom dome was examined using a three-dimensional prognostic model in cross-sectional form. Initially, the circulation due to a specified bottom dome and surface frontal system associated with observed domes are considered in isolation. Calculations revealed a cyclonic (anticlockwise) circulation in the surface layer, with an anticyclonic (clockwise) circulation in the near-bed layer, associated with an isolated bottom dome. In the case of the surface frontal system, calculations showed surface and near-bed circulations in the opposite directions to those found for a bottom dome. For the surface frontal case, the maximum current occurs at the sea surface, with a weak current at the bed. Calculations showed that topography had little effect. In subsequent calculations, surface front and bottom dome in combination were examined. In this case their form was not specified but was generated by solar heating, and calculations showed that topography had an important role. The opposing nature of the circulations associated with the surface front and bottom dome leads to a dominant near-surface cyclonic current circulation at the edge of the dome, with weaker secondary circulations beyond this. Cross-frontal circulation cells were generated in the vertical. The strength and exact form of these circulations depended upon the topography and parameterization of mixing.


Bronchial sensitivity test was done on a total of 50 allergic rhinitis patients with a view to assess the bronchial reactivity in subjects with allergic rhinitis. It was found that the bronchial tree in 31 (62%) of 50 allergic rhinitis patients was hyper-reactive to the specific allergen though they had not yet developed overt bronchial asthma. Bronchial challenge with histamine produced a positive response more often in patients with allergic rhinitis than in normal healthy individuals. A positive response to bronchial challenge was more likely when history, endermal test and nasal provocation tests were all positive to begin with, Long term follow up of this group of allergic rhinitis patients may indicate whether they are prone to develop bronchial asthma later.


Dry onions of the Granex type were undercut during harvest operations using both oscillating and rotating bar undercutters. Analyses on cleanliness, damage, and disturbance revealed that operating the rotobar with a rotational speed of 540 rpm, a depth of 25 mm below the soil surface, and a forward speed of 6.4 km·hr−1 ensured the most favorable results of the operating speeds, depths, and forward speeds evaluated. Depth of operation was the most important single factor.


An optical deterioration-accelerating weather and optical resistance testing device has a light source and a frame supporting a sample to be tested rotating around the light source. Thermal deterioration of the sample due to radiant heat generated by the light source is inhibited by the provision of a cold air guide enclosing a portion of the sample rotating frame on which the sample is supported. Cold air is introduced to the surfaces of the sample through the cold air guide to maintain the both sides of the sample at a constant test temperature.


The client of this project is the company Abilia, which specializes in aids for people with disabilities. Today the aids provided in the areas of communication and environmental control are expensive and hardly adaptable to personal preferences regarding appearance and size. Due to this Abilia now wants to modernize their products and develop a new concept based on a standard smartphone or tablet. The assignment was therefore to develop an encapsulation for a helping device which together with a smartphone or tablet would be able to replace the existing tools. To connect the helping device with the smartphone or tablet the assignment also included developing universal holders.The project began with a study which, for example, included a market study and a visit to one of Abilia's customers. Based on this study, and Abilia's requirements specification, the encapsulation of the helping device, later named Iris, and two universal holders for smartphones and tablets were developed. During the development process different methods were used, such as QFD, morphological matrix and moodboard.Iris serves as a communication tool due to its built-in speaker. When Iris is connected via Bluetooth to a tablet or smartphone, the user can write a message on the screen which is then played by Iris. The features for environmental control work in a similar manner, in this case the tablet or smartphone works as a remote control and sends commands to Iris via Bluetooth. The commands are then sent by Iris via IR or radio waves to other devices in the home.One small and one large universal holder have been developed. The smaller one is suited to smartphones and tablets from 4.5 inches to 8.9 inches and the larger fits tablets from 9.0 inches to 12 inches. The dimensions of the holders are adapted by using three adjustable arms which can be held in various positions by set screws. To provide support for smartphones and tablets with different thicknesses, the arms have been provided with angled grips, one of which can be removed without tools to facilitate insertion and removal. The holders are placed and fixed onto Iris using a trace function.


A Zn2+–silica modified CoFe2O4 (CZFS) nanostructured composite, useful for adsorbing cationic pollutants from water, was prepared by a wet-chemical method. The composite comprises cubic spinel crystallites (average 18 nm size) with amorphous silica clusters decorated on the crystallites-surface. Improved surface area (59.8 m2/g) of CZFS over those of Zn2+ modified CoFe2O4, CZF (32.6 m2/g), and CoFe2O4, CF (42.8 m2/g), together with its high negative ζ-potential of −35.4 mV (from surface SiO–) provides CZFS with improved adsorption capacity for Methylene blue (MB) over that of CZF and CF. MB adsorption (initial adsorbate concentration C0 = 5–25 mg/L) conforms to the Langmuir isotherm model, with maximum monolayer adsorption capacity Qm = 25.6 mg/g. CZFS exhibits adsorption efficiency Ae ≥ 98% for removal of heavy metal ions Cr3+, Cu2+ and Pb2+ (C0 = 5 mg/L). High Ae = 99.9% for Pb2+ dropped only to Ae = 98.8% for higher C0 = 20 mg/L (Qm = 19.8 mg/g). Saturation magnetization of 39 emu/g enables easy magnet...


We have arrived at the end of my investigative journey, as it were. But what is one to conclude from the various layers of results paraded across the previous chapters? The lessons are many. The objective behind this concluding chapter, therefore, is to bring order to this potentially unwieldy prospect by discussing the larger meaning of implicit attitudes for the study of immigration politics, specifically, and non-immigration politics, more generally. To effectively accomplish this task, I revisit – ever so briefly – the primary theoretical current running through this book, and the main tributaries of evidence on which it now draws. Against this backdrop, I discuss the implications of these findings for political scientists, especially those who study mass public opinion. This discussion forms the core of this chapter, and I organize it around five main points. First, I consider what my results suggest about the nature of public opposition to illegal and legal immigration, given the indelible role played by implicit attitudes toward Latinos in contemporary times. Second, I clarify how and why the evidence in this book establishes the viability of implicit attitudes and their corresponding measures for political science research. Third, I discuss the connection between implicit attitudes and ongoing debates over the nature of public opinion. Fourth, I explain the relationship between implicit attitudes and the idealized democratic citizen. And fifth, I spell out the implications of implicit attitudes for the political prospects of immigration reforms. Let's begin this effort by first reviewing my claims and evidence. Bottom Lines I defined implicit attitudes as basic affective evaluations of political objects. As such, they reflect citizens' learned but unspoken judgments of political objects as good or bad , favorable or unfavorable , or pleasant or unpleasant . I explained that implicit attitudes are steeped in automaticity. They are spontaneously activated, hard to control, and can operate outside of immediate awareness. Implicit attitudes, I pointed out, arise from people's mental capacity for associative reasoning. Even as part of our mind deliberates and reflects on political information, another part of our brain is engaged in identifying broad, but stable representations of what is typical in our environments. This part of our mind is geared toward uncovering, learning, and storing recurring patterns in information we encounter. And it is based on these patterns that we develop implicit attitudes toward political objects.


The international contracts of technology transfer are considered to be one of the most important agreements for the undeveloped countries for many reasons, firstly through these contracts the undeveloped countries could fill the gap between them and developed countries technically, ofcourse if they did well, secondly these contracts can also help the undeveloped countries to attain the growing levels which enable them to achieve prosperity and welfare for their citizens, still, those contracts arouse suspicions and they can lead to several lawful issues- yet I tried concentrating on preparing stage which precedes making an agreement and the responsibility of parties, for that what motivates me for that is the absence of lawful texts which regulate this phase inspite of its important. through this research I have tried to enlight some legal aspects about the contract negotiations, the preparing agreement other issues following the comparable approach thereby.


Currently, Mura assessment methods based on industrial cameras all require blurring and smoothing the original image to eliminate moire and other noise, which will cause the loss of image's details and may not be able to eliminate the interference of the moire pattern. Therefore, the accuracy of subsequent evaluation methods is limited. Due to the uncertainty of optical system and filter structure, it is difficult to establish a uniform standard to evaluate the the panel's quality. In this paper, a mura evaluation method based on the single pixel's brightness is tested by matching CSF filter with brightness map and transforming the brightness to grey level. Feature images with details retained can be obtained for mainly eliminate mura detection and evaluation. Based on IECTR62977-3-2 standard, the ability of mura evaluation by luminance map is verified and the mura detection results of camera captured images are compared. The results show that the mura evaluation method based on single pixel brightness can obtain better SNR and anti-moire ability, and also reduces the difference of optical devices. It should be noted that the similarity of brightness map restoration is mainly dependent on the following two points: 1. Accuracy of the extraction of luminance which determines the similarity of extracted luminance with the real one. 2. Establishment of Gamma lookup table which can be obtained by fitting multiple grey levels or assumed the panel's Gamma is 2.2 for rapid calculation We choose to use camera-A the resolution of which is 6576 × 4384 pixels with Nikon lens and camera-B with resolution of 10000 × 7096 with Cannon lens. They are both used to test a same OLED panel and then use IECTR629773-2's method to get evaluation score. Firstly, we evaluate the data directly from the original image, as shown in Fig.1, there is a little similarity between two different cameras. Then we change the original image to brightness map by trans brightness map to grey-scale image. The differences between optical devices are subtracted as shown in Fig. 2. Fig. 1. Test results based on camera captured image


The present investigation was to analyze and assess the sustainability of primary production of three types of peasant production systems, (T1, Pasture and cattle; T2, vegetables based in onion and T3, mixed farming) in the assembly of Irrigation Porotog in Cangagua, Region Cayambe, in the northern Sierra of Ecuador. Interactive monitoring and evaluation with producers during a cycle of field activities (equivalent to one year); evaluating indicators in the social, environmental and economic variables, which show the operation of the Office of Agricultural Production, UPA, as a family production system.
In the social variable, we found that the contribution of family PEA to the works on the UPA is majority in T1 and T2 systems; while the participation of children and the elderly is considerable in the T3. In terms of education the levels for the three types together, from 44 to 64% of family members, has just reached the primary education and the level of illiteracy is from 13-27%, which is the main problem to incorporate technological innovations to the UPA. The availability of basic services is 100%, but housing characteristics show that 40% of families have housing floor, which is an indication that there are limitations of family income. The contribution of labor, as a percentage of production costs was majority for the three typologies, which shows high dependence on family labor.


The ground‐state rotational spectrum of a dimer of ammonia and hydrogen bromide has been detected by using the technique of Fourier‐transform microwave spectroscopy in a Fabry–Perot cavity to examine a supersonically expanded gas pulse composed of ammonium bromide vapor entrained in argon. The spectroscopic constants B0, DJ, DJK, χ(14N), χ(79Br), and χ(81Br) have been determined (where appropriate) for the four symmetric‐top type isotopic species (14NH3, H79Br), (14NH3, H81Br), (15NH3, H79Br), and (15NH3, H81Br) and for the first of these the values are as follows: B0=3226.862(1) MHz, DJ=9.0(2) kHz, DJK=142.2(6) kHz, χ(14N)=−3.183(8) MHz, and χ(79Br)=361.245(6) MHz. The spectroscopic constants have been interpreted in terms of a hydrogen‐bonded dimer of C3v symmetry, having r(N⋅⋅⋅Br)=3.255 A and the hydrogen‐bond stretching force constant kσ=13.4 N m−1. A detailed analysis has demonstrated that χ(79Br) is consistent with a model of the dimer in which only a small electrical rearrangement in the HBr subuni...


The maxillary sinuses are largest of the paranasal sinuses and contained within the body of maxilla. After birth, the maxillary sinus enlarges with the growing maxilla, though it is only full developed following eruption of the permanent dentition. When teeth are lost, the maxilla reverts towards its infantile shape. Thus, its height diminishes and the alveolar process is reabsorbed. In the present study, anteroposterior, transverse and dimensions of maxillary air sinus of 90 subjects divided into 9 age groups were measured by CT scan. The study concluded that there was gradual increase in all three dimension from age groups 0-25 years and thereafter, a decrease in dimensions was observed.


Given the increasing number of frail hospitalised patients, a better adapted discharge summary to improve communication between primary and secondary care is necessary to protect the most vulnerable when returning to the community. The discharge summary is a communication tool vital to continuity of care, provided the information in the summary is …


In this paper, we treat Ryle's The Concept of Mind as a polemical work. The main question is as follows. On what grounds does Ryle associate "an intellectual tendency" he criticizes with historical Descartes? We defend the following thesis: "the Myth of Descartes" is a rhetorical construction that does not reflect the main aspects of Descartes' dualism. Two conclusions are drawn. First, without providing clear criteria for analysis, Ryle tries to give his work a systematic character through rhetorical means. Secondly, the contrasts between Meditations and "the Myth of Descartes" reveal that Ryle fails to give due reflection to his relationship with the philosophical tradition.


Polarization state generator is an indispensable part of polarization imaging system, produces the state of polarization for the calibration or test . Based on the analysis of the existing scheme, a novel Polarization State Generator is developed , which is constituted of a linear polarizer P and two liquid crystal phase variable retarders, denoted as LCVR1 and LCVR2. The transmission axes of P and LCVR2 are oriented horizontally, while the fast axes of LCVR2 is oriented. the state of polarization of the incident light is modulated through adjusting the control voltage of LCVRS. the experimental results show that the system not only is feasible ,but also has high sensibility. A good agreement is observed between theoretical and experimental results. Introduction Polarization generator is an indispensable part of polarization imaging system, in order to measure the instrument polarization sensitivity and monitor instrument performance requirements change, has the extremely high sensitivity. Laser is a common light source in polarization calibration, therefore, the polarizer , plate or other optical devices are placed in the laser beam path , thus can obtain the required for various polarization state laser beam [1 ]. In this paper, Based on the Stokes vector and Muller matrix theory, the traditional measurement technique, rotating wave plate driven by a motor, is replaced with Liquid crystal variable retarders (LCVRS), the phase retardation is controlled by the applied voltage, the polarization state of incident light is modulated accurately, eliminating the mechanical error, the polarization of laser generated is more accurate. Theory The Stokes Vectors of the light can be used to characterize the polarization properties of the light beam. The elements with the strength of the dimension, are all real Numbers, and can be easily measured and calculated, in the practical process of polarization detection, stokes vectors has become an important method to determine the polarization of the laser beam. In the Mueller calculus, the Stokes vector is used to described the polarization state of a light beam(where T denotes transposition).where is the total light intensity, the difference between the intensity of the horizontal (X) polarized component and that of the vertical (Y) linearly polarized component, the difference between the intensity of the linearly polarized component oriented at an angle of and that of the linearly polarized component oriented at an angle of , and the difference between the intensity of the left-circularly polarized component and that of the right-circularly polarized component[2-4]. The Stokes vector of the output beam can be written as: out in S M S = × (1) where in S is the Stokes vector of the input beam and M is Mueller matrices [5] of n optical elements respectively given by 1 2 1.... M M M M M n n − = International Conference on Intelligent Systems Research and Mechatronics Engineering (ISRME 2015) © 2015. The authors Published by Atlantis Press 382 Degree of Polarization(DOP),Linear Polarization(DOLP), Circular Polarization (DOCP),azimuth (θ )and ellipticity ( e ) can be obtained as: % 100 ) ( 0 2 3 2 2 2 1 × + + = S S S S DOP (2) % 100 ) ( 0 2 2 2 1 × + = S S S DOLP (3) ] 2 , 2 [ ) ( arctan 2 1 1 2 π π θ S S = (4) ] 4 , 4 [ ) arcsin( 2 1 2 3 2 2 2 1 3 π π e − + + = S S S S (5) Institutions Optimization Design The commonly used PSG is constituted of a linear polarizer P and a quarter-wave plate . Line polarized light can be produced by adjusting P. To produce a left-handed and a right-handed circular polarized light ,the transmission axes of P is oriented horizontally ,while the fast axes of the quarter-wave plate is oriented 4 ±π . The disadvantages is big volume,slow response,great mechanical error and so on.The rotating-retarder configuration can be replaced by one liquid crystal variable retarder[3] for determination of four complete Stokes vectors. The configuration greatly improves the response speed,improves accuracy, decreases the influence of mechanical rotating at the same time, but not completely eliminated. So the scheme based on dual LCVRS is presented. The system is constituted of a linear polarizer P and two liquid crystal phase variable retarders, denoted as LCVR1 and LCVR2,the structure diagram is shown in figure 1.


Rationing of treatment in the NHS in England is on the rise again, with patients around the country being denied access to care that just months ago was granted without question. Gareth Iacobucci reports


A faceted, metadata-driven approach to e-government information access is explored through the development of the FRED system. This paper describes first steps of this research, in which the quality of existing metadata in the Canadian context is examined, and the system framework is established. Future work will focus on mapping and supplementing existing metadata and evaluating the effectiveness of faceted information access in this domain.


Software Defined Networks (SDN) are a new paradigm that separates the data plane and the control plane, this means, among other things, that networks can be programmed via software applications running in an element called controller and this centrally communicates routing and security rules to devices on the network. In addition to conventional networking is migrating from IPv4 to IPv6 which shows the importance of testing and research using new protocols, technologies and tools in software-defined networking, in this specific case, the operation of IPv6. This document describes the development of a prototype IPv6 software defined networks and emulation processes conducted through Mininet tool and some controllers as RYU in order to strengthen and important contributions around the topic is displayed. Detailed documentation can be performed easily track the process with tutorials and explanations of the facilities, emulations, integrations


Molluscicides have gained a great attention in recent years and proved to be a good way of snail control. C. limon was tested as a molluscicide against adult Biomophalaria alexandrina snails and a larvicide against Schistosoma mansoni larvae (miracidia and cercariae). Lethal concentrations, LC50 and LC90 values were detected for both tests (744.17 and 1821.25 ppm, respectively). B. alexandrina snails, non-infected and infected with S. mansoni were exposed to Citrus limon peel extract concentration of 150 ppm for 4 weeks compared to non expoed with C. limon and/or infected controls. The meracidea, cercariae, egg production, protein electrophoresis and DNA fragmentation analysis and organ histology of B. alexandrina were assessed. C. limon exposure stimulated the growth rate, increased the number of eggs/snail/week (59.31 ± 5.71), inhibited reproductive rate by 20.6 %, hatchability rate (57.7 %) and stimulation of cercarial production. Histological investigation of C. limon extract exhibited necrosis and deformation of hermaphrodite and digestive glands of infected and non-infected B. alexandrina snails. C. limon exposure led to increase in total protein intensity of the hermaphrodite-digestive glands in both exposed/exposed-infected snails. RNA intensity was increased in C. limon exposed and exposed-infected snails during the experimental period. Necrotic DNA form was a characteristic of C. limon and/or infection. Key wards: Citrus limon, Biomphalaria alexandrina, molluscicide, proteins, DNA damage


Measurements of the angular dependence of the vector analyzing powers Ay and differential cross-section in dp-elastic scattering at Td = 2 GeV for the angular range from 10 ◦ to 35◦ in the c.m.s. have been performed. The obtained data are in good agreement with the existing data and theoretical calculations made in the framework of the relativistic multiple scattering model.


This analysis is conducted within the contect of a stochastic version of the Dornbusch (1976) overshooting model, following the Miller and Weller (1991) extension of Krugman (1991), with shocks to aggregate supply. Hence, three realistic features are added to the Krugman (1991) model: (i) home and foreign products are imperfect substitutes in consumption so that purchasing power parity is relaxed, (ii) prices and wages are sluggish, and (iii) there are intra marginal as well as infra-marginal interventions in the foreign exchange market. The objective of this paper is thus to show that mean reversion introduced by sluggish adjustment of prices and wages combined with a degree of intramarginal intervention can result in a hump-shaped exchange rate distribution and thereby explain the empirical evidence. We would like to show that the hump shape is more likely to occur when the degree of monetary accommodation is close to what is needed to peg the nominal exchange rate (so that the fundamental has to move far away from its mean for the exchange rate to reach its boundaries).


The permanent or regular monitoring of structures with sensors of any type can generate a consistent volume of data. Furthermore, it is often necessary to store additional information that is useful for the analysis of the measurements. Our experience has shown that the use of relational database structures can greatly simplify the handling of this large data- flow. With as appropriate data structure, the measurement data and other related information on the monitoring ne twork, the structure and its environment can be organized in a single file that will follow the structure's life in the years. This paper describes the data-structure that has been developed in the framework of the SOFO project. This database is capable of storing data from multiple types of sensors. It is now used at the unique interface between the data-acquisition (DAQ) software packages (for the different sensor types) and the data-representation and analysis packages (DRA). This approach has the advantage that the addition of new sensor types does generally not require changes in the DRA software and improvements in the DRA software are immediately applicable to all sensor types. The database structure is open, and any DAQ or DRA package can add fields and tables that are specific to its needs. In our experience, the use of relational database structures also greatly simplifies the quality management and can help in the certification of monitoring systems.


Data independent acquisition - mass spectrometry (DIA-MS) is becoming widely utilised for robust and accurate quantification of samples in quantitative proteomics. Here, we describe the systematic evaluation of the effects of DIA precursor mass range on total protein identification and quantification. We show that a narrow mass range of precursors (~250 m/z) for DIA-MS enables a higher number of protein identifications. Subsequent application of DIA with narrow precursor range (from 400 to 650 m/z) on Arabidopsis sample with spike-in of known proteins identified 34.7% more proteins than in conventional DIA (cDIA) with a wide precursor range of 400-1200 m/z. When combining several DIA-MS analyses with narrow precursor ranges (i.e., 400-650, 650-900 and 900-1200 m/z), we were able to quantify 10,099 protein groups with a median coefficient of variation of <6%. These findings represent a 59.4% increase in the number of proteins quantified than with cDIA analysis. This is particularly important for low abundance proteins, as exemplified by the 6-protein mix spike-in. In cDIA only 5 out of the 6-protein mix were quantified while our approach allowed accurate quantitation of all six proteins.


Introduction: Coronavirus infection COVID-19 is a new pandemic disease worldwide It is mainly a respiratory infection, manifested by fever, muscle aches, sore throat, shortness of breath, cough and in more severe cases - pneumonia, respiratory failure and death It has recently been found that COVID-19 can affect the gastrointestinal tract, cause heart damage, blood clotting disorders or impact the nervous system The review aims to summarize data from the literature and own observations of neurological complications in COVID-19 Material and Methods Based on keywords, scientific publications on various Internet platforms related to COVID-19 with neurological manifestations have been selected The most common clinical symptoms and syndromes found in the world practice are summarized Own experience in persons with COVID-19 treated at the Military Medical Academy - Sofia is analyzed Results Neurological manifestations in patients with COVID-19 include various symptoms and syndromes of the central nervous system, peripheral nervous system and skeletal muscles Most commonly, patients with COVID-19 have headache and/or dizziness, loss of smell or taste, and general muscle weakness Rarely, the disease is associated with Guillain-Barre syndrome, stroke, meningitis or encephalitis, cerebral and/or focal neurological symptoms, and other manifestations The recently established European Neuro-Covid Registry (ENERGY) of the European Academy of Neurology aims to establish the real incidence of neurological manifestations of the disease Conclusion: A review of the literature confirms that COVID-19 damages the nervous system, which may be asymptomatic or clinically manifested by a variety of cerebral and focal neurological symptoms and syndromes, the frequency of which is yet to be determined


The article is devoted to the study of the causes and conditions of spontaneous com- bustion of sulphide ores, which may result in endogenous fires that complicate mining operations in mines, causing enormous material damage to the national economy, and often also leading to human casualties. There are several sulphide-polymetallic deposits in Azerbaijan, the reserves of which were approved back in the days of the USSR. Of these, the Filizchay deposit is the most unique in terms of its reserves and ore composition. The development of other deposits adjacent to the Filizchay deposit, separately, is inexpedient because of their small reserves. However, the development of sulphide-polymetallic deposits in Azerbaijan is complicated by the revealed tendency of industrial types of ores to oxidation and spontaneous combustion. In this regard, there was a need for a special study of the chemical activity of sulphide ores and the phenomena accompanying oxidative processes, taking into account the natural features of the deposits in order to obtain the initial parameters necessary for scientifically based technological solutions for their development. Sulphide ores of sulphide -polymetallic deposits of Azerbaijan significantly differ in material composition, conditions of occurrence and mining technical features of their development from the listed deposits, the issues of spontaneous combustion of which have been studied for a long time. Until now, there are no general criteria for assessing the fire hazard of sulphide ores, suitable for any deposit, since the conditions for the occurrence of underground fires at different deposits are different. It is this circumstance that makes it necessary to conduct special studies for each deposit separately. Therefore, the need for a special study of this problem on the example of the conditions of sulphide-polymetallic deposits in Azerbaijan, which are prone to oxidation and spontaneous combustion, is of great importance. Identification of causes and factors affecting spontaneous combustion of sulphide ores, classification of sulphide-polymetallic deposits of Azerbaijan according to the degree of their tendency to spontaneous combustion by analyzing the collected materials, as well as by the results of studies to determine the oxidative activity of sulphide ores. The article presents the results of experimental studies to determine the oxidative activity and spontaneous combustion of sulphide ores of the Katsdag, Filizchay and Katekh deposits, carried out in laboratory conditions by the method of Institute of Mining named after. A.A. Skochinsky, the basis of which is the determination of the oxygen absorption rate constant. It is known that the susceptibility of ore to spontaneous combustion is determined by its oxidizability at low temperatures and depends on a large number of factors. In this regard, the dependence of the total amount of oxygen absorbed by sulphide ores on time has been studied, it has been established that the rate of oxygen absorption by sulphide ores is long-live and slowly fading, but incessant. On the basis of extensive experimental material, a classification of sulphide ores of Azerbaijan according to the degree of tendency to spontaneous combustion according to low-tempera-ture oxidation is proposed, since it is this that forms the basis of the spontaneous combustion process. The classification is also based on differences in textural and structural features and mineralogical composition of ores. Of great interest is also the influence of the size of the free reacting surface of the ore on the oxidation process. Analysis of ore samples shows that for their spontaneous combustion, the most dangerous are its coarse fractions than the dust. The results of the conducted studies allow a scientifically sound approach to planning the sequence of development and designing mines.


Isolations from turf samples with brown patch symptoms and pathogenicity tests indicated that Rhizoctonia solani AG-1 IA was the most important pathogen causing brown patch of tall fescue (Festuca arundinacea) in Arkansas in 1992. Ten tall fescue cultivars were evaluated for susceptibility to R. solani in sun and shade environments. Plants were grown in a greenhouse for 4 wk under either full sunlight or colored cellophane that simulated the quality and quantity of light obtained in the shade of deciduous tree canopies. Plants were then evaluated for disease reaction in growth chambers under similar sun or shade conditions. Shade-grown plants of all 10 cultivars had significantly greater disease severity than sun-grown plants (P=0.05)


Nanoscale cesium-pollucite zeolite (ANA topology) free of organic template is synthesized free of organic template. The crystallization is taken place at mild temperature and pressure (180 °C, 22 bar) compared to previous works. Powder XRD analysis reveals that the nanocrystals can be crystallized from a clear precursor solution of 16.5SiO2:1Al2O3:5.3Cs2O:175H2O within 50 h. The resulting nanocrystals exhibit trapezohedron shape and has a Si/Al ratio of 4.11. The nanocrystals possess a mean particle size of 79.4 nm and they are colloidally stable in water. In addition, Perkin condensation of benzaldehyde with acetic anhydride catalyzed by nanosized Cs-pollucite zeolite under non-microwave instant heating condition is also demonstrated and discussed.


In this paper, we present different dynamical behaviors of micro particles in a droplet in the surface acoustic wave (SAW) field generated by using an annular interdigital transducer (AIDT). It was found that the micro particles can be forced into a ring type pattern, rotational or aggregating motions under the different experimental conditions. The propagation of SAWs results in a corresponding deformation of the substrate and the degree of deformation reflects the magnitude of the force. The simulation results show that the contour of the displacement in some area was similar to a ring, which indicates a standing acoustic wave field is formed throughout the droplet and the particles are hence forced to a ring type pattern. In the case that the acoustic radiation force acting on the micro droplet placed in the center of the device is nonsymmetrical, the particles in the droplet will be subject to an unbalanced force and driven into a rotational motion. The simulation results indicate that the anisotropic elastic properties of the LiNbO3 substrate and the nonsymmetrical SAW radiation force on the micro particles are the key factors leading to these phenomena.


A new pentacyclic triterpene acid, elliptic acid was isolated from the ethanolic extract of the leaves of Rubus ellipticus. On the basis of physical evidences coupled with chemical investigations, the structure of elliptic acid was given as, 3,7, 11-trihydroxy ursolic acid.