A man aged 64 years presented to emergency department with chest pain and shortness of breath. On cardiac auscultation, he had loud P2 and parasternal heave; however, lung auscultation was normal. Bilateral lower limb pitting oedema was present. CBC, CMP and cardiac biomarkers were normal. D-dimer and CT chest were performed and it excluded pulmonary embolism. His EKG was suggestive of right ventricular strain. He was being treated for systemic and pulmonary hypertension, taking carvedilol 3.125 mg two times per day, furosemide 40 mg once daily, sildenafil 20 mg three times a day, treprostinil 0.5 mg two times per day, amlodipine 2.5 mg two times per day, atorvastatin 40 mg once daily, aspirin 81 mg once daily and clopidogrel 75 mg once daily. Trans-thoracic echocardiography showed his systolic function was normal, his estimated ejection fraction was 60–65% with markedly dilated right ventricle (RV), …


The need of water is a major media of irrigation in order to support the effectiveness of agricultural business which is manifested as the supporting of food provision. The purpose of this study is to analyze the amount of discharge in each channel and the efficiency in Kobisonta irrigation area, Seti North Seramsubdistrict, Central Maluku district with area of 3,150 ha. The study was conducted on secondary channels Kobisonta includes BKS7, BKS8, BKS9, Kobisonta Secondary Channel includes BKS10, BKS11, BKS12 and Seti Secondary Line includes BS1, BS2 and BS3
The water debit requirement in the rice field and the efficiency in the irrigation area of Kobisonta was analyzed by using the incoming debit - discharge method based on flow velocity measurement. Providing irrigation water for efficiently is not simple because many factors affect the way and the process, besides that if the water supply and irrigation on the channel is inefficient, then it can reduce or decrease agricultural productivity.
From the result of actual debit analysis on channel BS3, BKS9, BKS11, and BKS12, they are able to meet therequirement of irrigation water thoroughly in irrigation area. In BS1, BS2, BKS8 and BKS10 channels, actual discharge has not been able to meet the irrigation water needs in its irrigation area. The efficiency of irrigation channels in Kobisonta Irrigation Area varies by channel. According to the efficiency standard by the Directorate General of Irrigation, the secondary Saluaran in Irrigation Area is categorized as efficient where for BKS7 is 90%, BKS8 is 97% and BS2 is 91%.


Reactive oxygen species (ROS) generated during cellular respiration oxidize various cellular constituents, which cause carcinogenesis. Since most studies on the role of ROS in carcinogenesis have mainly been performed using tumor-derived cell lines, which harbor various types of mutation, it has been difficult to determine the molecular details that lead to cancer formation. To overcome this difficulty, we established human iPS cell lines in which the intracellular ROS levels are controlled at various differentiation stages by manipulating the ROS-yielding mitochondria. By introducing a specific amino acid substitution (I69E) into the SDHC protein, a component of mitochondrial respiratory chain complex II, the ROS level increased considerably. When ROS-overproducing cells at the early stage of endoderm differentiation were subcutaneously inoculated into the backs of nude mice, we observed tumor formation. These tumor-initiating cells were subjected to a comprehensive analysis by RNA-sequencing. It was revealed that tumor-initiating cells showed 27 up-regulated transcripts compared with control cells. The newly identified genes include those coding for PAX8 and FOSB (transcription factors) as well as FGF22, whose expressions are known to increase in developing embryos. These results suggest that these genes may play a pivotal role in cancer formation at the very early stages of cell differentiation.


Anthropology brings a uniquely holistic sensibility to the study of water. It examines water from multiple dimensions and in its myriad forms to understand the many ways that people make meaning and a living from water. Anthropology's study of water provides a foundation for contemporary application and practice by anthropologists and others toward solving a wide range of water-related problems. In this introduction, we introduce the seven articles that form this special issue on applied anthropology and water. Collectively, the articles provide valuable and diverse insights on the application of anthropology to a wide range of water issues. The articles also demonstrate the capacity of research and practice centered around applied anthropology to highlight local impacts and responses at multiple scales and across institutions. Here, we discuss four thematic areas shared across the articles that suggest wider commonalities for applied anthropological research and practice. These areas are configurations of clean water access; multiplicity and heterogeneity of the lived experiences of water; injustice, inequities, and inequalities related to water; and ethnography in applied research on water. We conclude by suggesting characteristics and qualities of applied anthropological research on water, which might guide future research and practice.


The documentation of interventions by hospital pharmacists has been on-going for over three decades through various available means; with recent national surveys suggesting that the majority of hospital pharmacists continue to document their interventions on a daily basis.1-5 Pharmacist intervention encompasses all activities relating to safe medication utilisation and optimising therapeutic outcomes for patients in conjunction with other health care professionals which ultimately improves patient management or therapy'.5'6


AbstractThis work aims at optimizing a helmet. First a discrete dynamic model of a helmet has been proposed for modeling the free fall of the helmet from a height of 2m. The model was solved using Runge Kutta method. The time history of head acceleration has been extracted from this solution and 'Time bound peak acceleration criteria' of head injury has been computed After preparing the model it was validated using available experimental and FEM results. The model was then used for optimization. The objective of optimization is to minimize 'time bound peak acceleration' which is taken as an injury criterion representing the effectiveness of the helmet. The optimization is constrained to a maximum total mass and total thickness of the helmet. The optimization has been carried out using conventional method as well as genetic algorithms. Subsequently the sensitivity of the objective function with respect to different design parameters was studied.


Particularly vulnerable tribal group (PVTG) earlier called as Primitive tribal group (PTG) is a Government of India classification created for the purpose of enabling improvement in the conditions of certain communities with particularly low development indices. In India, 75 communities are regarded as PVTG and in West Bengal only three communities are regarded as a PVTG viz. Bihor, Lodha and Toto. In this study, we have made an attempt to study the implementation of various types of developmental programmes of the Central and State Governments among the two communities (Birhor and Lodha) of Purulia and Paschim Medinipur District of West Bengal. In the post-Independence period the main aim of the Government was to put off the stigma of criminal tribe designation of the Lodha-Sabar community. At the same time the Government also wanted to uplift the socio-economic condition of the Primitive Tribal Groups (PTG) like Lodha-Sabar and Birhor who mainly depended on forest produce and daily labour. The study revealed that the major constraint of the implementation of the developmental programmes among the Lodhas and Birhors lie in their landlessness and poverty. The study also revealed that how the developmental state failed to implement its stated good policies for these communities. Finally, some recommendations have been made about how a better implementation could be made to bring confidence among the Birhor and Lodha community towards the improvement in their living condition. (232)


The Isolation Process, contained in the 231 Building, has an operational cost of approximately $35,000 per month. The location of this process in the 224-T Building would result in lower manpower requirements and effect an estimated savings of $5,000 per month. This report details study made to determine the feasibility and approximate cost for installing this process in 224-T.


Conditions for the solrability of entire (0, m1,...,mq) interpolationhave been given by Liu Yongping. In this paper, the saturation rate and class of theseoperators is determined in LP(R) Spaces (1≤ p +∞).


The research on bee and mite biology over the past 20 years has uncovered numerous details of the A. cerana-V. jacobsoni co-adaptation which are systematically summarized here. A. cerana acquired a high degree of hygienic efficiency with a differentiated set of behavioural traits that we describe in this review in a broad sense to include grooming of mites by adult bees, uncapping and removal of infested brood and entombing of infested brood. Approximately 20 % of the reproducing mite population can be eliminated by entombing of lethally parasitized drone pupae. In their equally effective infesting behaviour the parasites explore the most suitable adult and larval host individuals for safe phoretic positions, the favourable caste and suitable age. A. cerana compel V. jacobsoni to reproduce exclusively on drone brood hosts. This limited reproduction, in combination with char- acteristics of the population dynamics of the host, are key factors which limit mite populations to tol- erable levels. © Inra/DIB/AGIB/Elsevier, Paris


Acute spontaneous intracerebral hemorrhage (ICH), the most severely disabling type of stroke, has few proven therapies. The mainstay of care remains acute blood pressure (BP)–lowering treatment, in order to mitigate hematoma expansion, perihematomal edema, and the attendant mass effects, each linked to early neurologic deterioration (END), death, and major disability.1,2 More than 5 randomized clinical trials (RCTs) have proven the safety and support the efficacy of early intensive BP-lowering treatment, as opposed to conservative BP control. These trials include the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial 2 (INTERACT-2) and Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-2) trials, which were recently compared3 and compiled in a large meta-analysis.4 Mounting evidence,1 particularly ad hoc analyses of INTERACT-2,5,6 suggests that the earlier the treatment, the steeper the drop, and the lower the BP achieved, the better the outcome,1,6 halting radiologic or clinical deterioration2 and, more importantly, improving quality of life and shifting toward better functional physical outcome at 3 months.4–6 Furthermore, INTERACT-2 data revealed a dose effect with linear relationship between achieved systolic BP (SBP) and reducing hematoma growth5 and improved functional outcome.6


Traditional methodsoflogging systemactivity arefundamentally insecure, whichmeansthatanattacker maycompromise ortamperthelogs. A novelmethod, Xen- basedsecure logging system call, isusedtoprovide tamper- freelogsofsystem call forsomeintrusion detection analysis techniques, whichonlyrequire sequences ofsystem call within a userprocess. Preliminary evaluation showedthatthe prototype issimple andefficient. Keywords-VMM, VM,Xen,guestOS,hypercall, system call


This paper discusses the calculating method for designing driving torque of tunnel boring machine(TBM) cutterhead in different geological conditions, which helps to optimize the TBM structure and total installation power,and improve its capability to suit in all kinds of geographic conditions.The BM264-311 TBM,made and designed by ROBBINGS Company for Liaoning Dahuofang Reservoir Water Diversion Project,is taken as an example for computing simulation,which proves that the computing method is rational and efficient.


The displacement amplification and hysteresis of parallel four-bar mechanism using piezo actuator were researched in this paper. The displacement amplification was analyzed by employing the material bending theory firstly. Theoretical and FEM analysis proved that the amplification ratio of parallel four-bar mechanism is only related to the position of driving point and the guiding arm displacement is directly proportional to the input with the certain structure. Then the Preisach model was employed to model the hysteresis of guiding arm and using the model to perform the research on the output displacement of the mechanism. Experiments proved that the analysis is correct and showed that this model can effectively improve the accurate of the guiding arm output displacement and can realize output arbitrary series displacement using the Preisach interpolation surface.


Labelling of proteins and lipids of 20 organs and tissues of the rat was studied 4 h after subcutaneous injection of D(+)-[U-14C]glucose. Gross differences between the rate of labelling of acid-ins...


The International Committee for Weights and Measures (CIPM) has consultative committees covering various areas of metrology. The Consultative Committee for Ionizing Radiation (CCRI) differs from the others in having three sections: Section (I) deals with radiation dosimetry, Section (II) with radionuclide metrology and Section (III) with neutron metrology. In 2003 a proposal was made to publish special issues of Metrologia covering the work of the three Sections. Section (II) was the first to complete their task, and their special issue was published in 2007, volume 44(4). This was followed in 2009 by the special issue on radiation dosimetry, volume 46(2). The present issue, volume 48(6), completes the trilogy and attempts to explain neutron metrology, the youngest of the three disciplines, the neutron only having been discovered in 1932, to a wider audience and to highlight the relevance and importance of this field. When originally approached with the idea of this special issue, Section (III) immediately saw the value of a publication specifically on neutron metrology. It is a topic area where papers tend to be scattered throughout the literature in journals covering, for example, nuclear instrumentation, radiation protection or radiation measurements in general. Review articles tend to be few. People new to the field often ask for an introduction to the various topics. There are some excellent older textbooks, but these are now becoming obsolete. More experienced workers in specific areas of neutron metrology can find it difficult to know the latest position in related areas. The papers in this issue attempt, without presenting a purely historical outline, to describe the field in a sufficiently logical way to provide the novice with a clear introduction, while being sufficiently up-to-date to provide the more experienced reader with the latest scientific developments in the different topic areas. Neutron radiation fields obviously occur throughout the nuclear industry, from the initial fuel enrichment and fabrication processes right through to storage or reprocessing, and neutron metrology is clearly important in this area. Neutron fields do, however, occur in other areas, for example where neutron sources are used in oil well logging and moisture measurements. They also occur around high energy accelerators, including photon linear accelerators used for cancer therapy, and are expected to be a more serious problem around the new hadron radiation therapy facilities. Roughly 50% of the cosmic ray doses experienced by fliers at the flight altitudes of commercial aircraft are due to neutrons. Current research on fusion presents neutron metrology with a whole new range of challenges because of the very high fluences expected. One of the most significant features of neutron fields is the very wide range of possible neutron energies. In the nuclear industry, for example, neutrons occur with energies from those of thermal neutrons at a few meV to the upper end of the fission spectrum at perhaps 10 MeV. For cosmic ray dosimetry the energy range extends into the GeV region. This enormous range sets a challenge for designing measuring devices and a parallel challenge of developing measurement standards for characterizing these devices. One of the major considerations when deciding on topics for this special issue was agreeing on what not to include. Modelling, i.e. the use of radiation transport codes, is now a very important aspect of neutron measurements. These calculations are vital for shielding and for instrument design; nevertheless, the topic has only been included here where it has a direct bearing on metrology and the development of standards. Neutron spectrometry is an increasingly important technique for unravelling some of the problems of dose equivalent measurements and for plasma diagnostics in fusion research. However, this topic is at least one step removed from primary metrology and so it was felt that it should not be covered, particularly as a compendium of papers on spectrometry for radiation protection has been published relatively recently [1]. The CIPM Mutual Recognition Arrangement (CIPM MRA), whereby national measurement standards and certificates issued by different national metrology institutes (NMIs) can be recognized internationally, is covered only briefly, although the key comparisons which underpin the CIPM MRA are highlighted. The papers included in this issue concentrate on the primary physical quantities—neutron source emission rate and neutron fluence, papers on the latter quantity covering the wide range of neutron energies for which standards are required. Neutron cross sections are fundamental to neutron physics and their importance in neutron metrology is also covered. A large amount of work by acknowledged experts in neutron metrology has gone into the preparation of this special issue and we are indebted to them for their time and effort. The list of contributors begins with the authors of the papers but also includes the referees who provided invisible but invaluable input. We are grateful for the support and encouragement of Professor Georgio Moscati, president of the CCRI when the work was proposed, Dr Kim Carneiro the current president, and Dr Penny Allisy-Roberts the executive secretary of the CCRI. When this work was first proposed a list of potential topics was drawn up by the then chairman of Section (III) Dr Horst Klein. It is a measure of his insight and knowledge of the field that the resulting document matches almost exactly the original plan he drew up. This special issue is thus a tribute to his very extensive contribution to the field. We sincerely hope its contents provide an accurate picture of the present state of neutron metrology in view of Dr Klein's conviction of the importance in metrology of getting things right. Reference [1] Thomas D J and Klein H (ed) 2003 Neutron and photon spectrometry techniques for radiation protection Radiat. Prot. Dosim. 107 1–204


In this paper,through the practice of sports teaching process,truly appreciate the importance of body language,no matter passing emotion,but also adding audio language to make it more image,accurate and complete representation of the whole process.It is basis of quality and quantity to complete the task of teaching.It is positive and significant that PE teachers make full use of body language to improve the quality of teaching.


A R T I C L E I N F O A B S T R A C T Article history: Received: 19 November, 2020 Accepted: 06 January, 2021 Online: 22 January, 2021 The development of wind farms requires an optimal design of wind turbines layout. The main goal of this optimization is to minimize the wake effect through the optimal placement of the wind turbines. The current study aims to standardize the wake losses among all wind turbines in the wind farm and bringing their losses to a similar level. An objective function was developed for this purpose, and used by the genetic algorithm to maximize the farm energy output and prevent the wake concentration on specific wind turbines. The proposed method has been applied to the Gasiri Wind farm through a simulation approach. The applied optimization process has shown very promising results characterized by a 17% possible energy gain after the adoption of the optimized layout. The study has also shown that the new positions of wind turbines characterized by a high rated power, are more on a forward position following the wind direction compared to the original ones. The study has also shown that there is a significant reduction of mechanical fatigue on the wind turbines blades.


A welfare ranking of alternative commercial policies is constructed for the mobile capital Harris-Todaro economy. It is sh own that, despite the presence of unemployment, most noninterventioni st policies suggested by the competitive model of gains from trade ca rry over to the mobile capital Harris-Todaro economy. Yet in contradi ction to the competitive model, it is shown that all forms of trade i ntervention are not detrimental to welfare. Only those that reduce th e volume of trade are. The export promotion policies so copiously fol lowed by developing countries are vindicated, but their import substi tution policies are shown to be without justification. Copyright 1987 by The Review of Economic Studies Limited.


Nowadays, the use of information technology (ICT) in education is nothing new. But the question is where the limit is when the use of ICT does not have the desired effect. In the paper we discuss the use of simulations in the teaching process that can positively influence students' achievements. At the beginning of the paper we present the results of a research aimed at exploring the impact of the use of computer simulations on secondary school students' understanding of oscillatory motion. The aim of the research was to explore the effect of the use of simulations on students' abilities to work with graphs and to find out relevant information. In the conclusion, the possibilities of integration of simulations into the teaching process are discussed.


Many internet auction sites implement ascending-bid auctions. Empirically, "late" bidding is frequently observed in "hard-close auctions." In "soft-close auctions," late bidding is less frequently observed. In this paper, we introduce an independent privatevalue repeated internet auction model to explain the observed bidding behavior. We use Þnite automata to model repeated auction strategies. We run learning simulations using artiÞcial bidders who update their strategies via a genetic algorithm. This model explains the observed bidding behavior successfully. We also investigate interesting properties of the evolving strategies.


Introduction: Blood transfusion plays an vital role in patients management and is live saving in my instances. it plays a pivotal role as a specialized modality of treatment and saves millions of lives worldwide each year and reduces morbidity. Stringent screening of blood not only ensure safe supply of blood and blood products, but also gives us idea about prevalence of ttis among general population
Objective: to determine the serroperavalance of tti among blood donors in lalded hospital
Materials and methods: A retrospective study was carried out over a period of 3 years from January 2017 to December 2019.serum samples were screened for hepatitis B surface antigen ,antibodies to human immunodeficiency virus Type 1 and 2 ,hepatitis c virus and syphilis in department of transfusion medicine was carried out
Result: The result shows that 55 (3.72%) of the blood donors had TTIs. The prevalence of Hepatitis B, Hepatitis C, Malaria, Syphilis and Human immunodeficiency viruses (HIV), was found to be 31(0.21%), 23 (0.15%), 01 (0.0.006%), 01 (0.006%) and 02 (0.0.23%) respectively. None were positive for malaria.
Conclusion: Transfusion Transmittable Infections pose a threat to patients admitted in any health care facility and if not carefully screened for will cause significant morbidity. Careful screening of all donor blood units in the blood bank of a hospital is absolutely necessary to prevent any untoward incidence of TTI in patients admitted to a health care facility
Keywords: Transfusion, Sero-Prevalence, Donors, Transfusion Transmissible Infections.


Objective To study whether tumor necrosis factor-α (TNF-α) transduction neurocyte apotosis exists in the temporal lobe of human refractory temple lobe epilepsy (TLE). Methods The brain samples were obtained from 30 patients with refractory TLE (TLE group) and 10 patients with brain trauma (control group). SP staining of immunohistochemistry was used to detect the expression of TNF receptor-assosiated death domain protein (TRADD),apoptosis-signal-regulating kinase 1 (ASK1) and caspase 8 in neurons and gliocytes. The ulstastructural changes of neurons,gliocytes in the foci of TLE were observed by transmission electron microscope. Results The expression of caspase 8 in neurons and gliocytes of the TLE group increased compared with that of the control group (P0.05,P0.01 respectively). TRADD and ASK1 were not expressed in neurons and in gliocytes in the two groups. Under transmission electron microscope,distinctive apotosis changes were found in neurons of the TLE group: the neurons becoming small in volume,nuclear pyknosis,heterochromatin increasing and marginal collection,shrinkage of cytomembrane and nucleolemma,nuclear division,and apoptotic bodies forming. Astrocytes became swollen. Conclusions TNF-α transduction cell apotosis may exist in neurons and gliocytes of the temporal lobe tissue in patients with refractory human TLE.


Modern radar system has multimode and mutlifunction capability with sophisticated signal processing algorithms for different operational scenarios. Development of these signal processing algorithms, performance enhancement and adaptation based on field results requires in depth analysis of baseband data collected during radar operation. Towards this data recording and management plays a vital role. The design of such system for radar shall support H/W and S/W features for real time recording, playback and off line extraction of whole or selective portion of radar baseband data. It shall also support long term data storage and retrieval. Although data recording requirement is same for different radar applications but constraints for size, weight and power is additional and critical for airborne radars. Hence, more emphasis is given for data recording and management for airborne radar. The requirement capturing, design and evaluation of data recorder for airborne radar along with data management philosophy is brought out as three layer approach in this paper.


A novel method, called adaptive pulse coupled neural network (AD-PCNN) using a two-stage denoising strategy, is proposed to reduce noise and speckle in the spectrograms of Doppler blood flow signals. AD-PCNN contains an adaptive thresholding PCNN and a threshold decaying PCNN. Firstly, PCNN pulses based on the adaptive threshold filter a part of background noise in the spectrogram while isolating the remained noise and speckles. Subsequently, the speckles and noise of the denoised spectrogram are detected by the pulses generated through the threshold decaying PCNN and then are iteratively removed by the intensity variation to speckle or noise neurons. The relative root mean square (RRMS) error of the maximum frequency extracted from the AD-PCNN spectrogram of the simulated Doppler blood flow signals is decreased 25.2% on average compared to that extracted from the MPWD (matching pursuit with Wigner Distribution) spectrogram, and the RRMS error of the AD-PCNN spectrogram is decreased 10.8% on average compared to MPWD spectrogram. Experimental results of synthetic and clinical signals show that the proposed method is better than the MPWD in improving the accuracy of the spectrograms and their maximum frequency curves.


Naturally occurring radioactive material (NORM) contamination usually can be easily detected on the outside of piping or tanks in refineries by taking external gamma measurements with simple count rate meters or more complicated gamma spectroscopy instruments, as radium and progeny emit many gamma rays when in equilibrium. However, due to special processes and certain circumstances, a significant amount of NORM may be present without the characteristic gamma signature of radium and its progeny. We found that during the process of cracking ethane and methane from crude oil, radium is not deposited while the daughters are deposited. When this occurs, measurements taken on the outside of piping indicate no elevated levels of gamma radiation; however, elevated levels of alpha and beta radiation may be detected on the inside of the piping. When analyzing the contents on the interior of the pipe for gamma radiation, the contents contain only lead-210 ( 210 Pb). This indicates that all parents have decayed or that 210 Pb was the only NORM that was deposited.


The library-oriented sub-system of Jiangsu Huiwen automatic periodical management system is designed based on the traditional integrated operation model of periodicals. Through discussing the advantages and analyzing its deficiencies, the paper has put forward suggestions.


Abstract— The effects of high circulating concentrations of several amino acids on the free amino acids of rat brain were measured, to see whether or not the results followed any consistent pattern. High circulating concentrations of large, neutral amino acids (phenylalanine, valine or isoleucine) caused significantly decreased values only of other large, neutral amino acids in the brains. High circulating concentrations of the basic amino acids lysine or arginine caused significantly decreased values only of each other. The data suggest that there are separate systems for the transport of neutral and basic amino acids across the blood‐brain barrier. The effects of valine and lysine on the uptake by brain and the con‐vulsant action of allylglycine (a neutral amino acid) were consistent with the concept of separate systems for the transport of amino acids across the blood‐brain barrier. Valine inhibited the uptake by brain and the convulsant action of allylglycine in mice, but lysine did not. The data suggest that allylglycine and valine are transported into the brain by a common mechanism that does not transport lysine.


Objective To investigate the bilateral flow-mediated dilation of brachial artery (BA-FMD) and nitroglycerin mediated dilation (BA-NMD) in patients with cerebral infarct, and to find out if the vasodilation of internal catotid artery after sublingual administration of nitroglycerin can be detected as a more direct way to reflect the vasodilation in patients with cerebral vascular diseases. Methods High resolution ultrasonic system was used to measure 13 patients with acute cerebral infarction. The diameter of brachial artery, internal carotid artery and common carotid artery was measured at relaxation, reactive congestion in the brachial artery and after sublingual administration of nitroglycerin. Meanwhile, the intima media thickness (IMT) and plaques of carotid artery was detected. Results Paralysis did not lead to differences in vasodilation of brachial artery (r=0.52, P=0.07). There was a correlation between ICA-NMD and BA-NMD (r=0.83, P=0.01). Conclusion There were no significant differences between brachial vasodilation in paretic and non-paretic limbs of patients with acute cerebral infarction. Ultrasonic measurement of ICA-NMD can be a more direct measure of the vasodilation of patients with cerebral infarction.


COOPERATIVE STORAGE WAREHOUSES have been suggested as a possible means by which large libraries may, with minimal expenditures, retain and even acquire infrequently used but potentially valuable research material. Three types of this facility exist in the United States today. The first, exemplified by the New England Deposit Library (NEDL), is a central storage warehouse owned and operated by several participating libraries. Each member merely rents space in a jointlyowned building, determines how its space is to be used, and maintains its own collections. The second type, illustrated by the Hampshire Inter-Library Center (HILC), is a consolidated warehouse owned and supported by a group of cooperating libraries. Each member contributes its little-used serials to the warehouse, which completely integrates the resulting collection. Contributed funds and income from the disposition of duplicates provide for a limited acquisitions program of rarely-consulted serials and expensive sets. The third type, illustrated by the Midwest Inter-Library Center (MILC), is distinguished from the preceding two types by the scope of its operations and holdings. Materials deposited by members are absorbed into the collections when deposit limitations permit, and duplicates are discarded. Unlike the others, this type has a professional staff which operates library programs approved by the membership and which carries on an acquisitions program designed to supplement members' collections as well as to strengthen library resources in the region. A range of services is provided for the membership and, under certain conditions, for nonmembers as well.


Introduction : Dental fluorosis is a chronic condition of enamel hypomineralization resulted from excessive ingestion of fluoride during tooth development. Different treatment protocols were used to improve esthetic appearance of fluorosed teeth. Aim : To evaluate patient satisfaction on esthetic improvement of mild to moderate fluorosed teeth after treating with different minimal-invasive treatment modalities. Patients and Methods : Sixteen participants were randomly assigned in 8 treatment protocols with 20 teeth at each protocol ( n=20 ). ( P 1 ) Opalescence boost PF 40%. ( P 2 ) Opalustre. ( P 3 ) MI-Paste Plus. In ( P 4 ) teeth were treated with Opalustre + Opalescence boost PF 40%. In ( P 5 ) Opalescence boost PF 40% + MI-Paste Plus, while in ( P 6 ) Opalustre +MI-Paste Plus. Whereas ( P 7 ) Opalustre + Opalescence boost PF 40% + MI-Paste Plus. ( P 8 ) control. Patient satisfaction was gauged using a visual analog scale (VAS) at 4 different time points; immediately after application (T 1 ), 14 days later (T 2 ), 3 months later (T 3 ), and 6 months later (T 4 ). Results : All treatment protocols showed significant difference over control group at all evaluation times. Regarding treatment protocol, the highest patient satisfaction was recorded in P 4 and P 7 . The lowest patient satisfaction was recorded in P 3 . Moreover, concerning evaluation time the highest patient satisfaction was recorded at T 3 and the lowest patient satisfaction was recorded at T 1 . The highest patient satisfaction was recorded at 14 days evaluation of P 4 and 6 months evaluation of P 7 . Conclusion : The combined treatment protocol of Opalustre™ and Opalescence™ boost™ PF 40% provided the highest "patient satisfaction» in treating mild to moderate fluorosed teeth regardless of using MI-Paste Plus®. MI-Paste Plus® provides stability of patient satisfaction results at 6 months' follow-up. fluorosis is an esthetic disturbance that result from interrup-tion of enamel development particularly at maturation. Enamel fluorosis prevalence has increased in the previous two decades, corresponding to the worldwide decline in caries. This can be clarified by excessive ingestion of fluoride from drinking water or in the form of topi-cal fluoride supplements that are incorporated in enamel during tooth development. 1


Abstract : The ability to interface C4I systems with simulations represents a powerful approach for analyzing complex military plans, and generating appropriate courses of action. The simulations provide a context of the real world, in which the plan can be exercised, what-if's can be performed, and intelligent courses of action can be generated. To build more intelligence in our ability to generate courses of action, we must be able to decompose plans from C4I systems, so that critical events and actions/consequence relationships can be understood. Through this understanding, we can begin to intelligently monitor how the execution of the plan may be deviating from the original simulated plan. This paper will describe technology development allowing High Level Architecture (HLA) Run Time Infrastructure (RTI)-based simulations to interact with grid-aware software agents, allowing those agents to intelligently decompose planning information from systems such the Global Command and Control System-Maritime, or GCCS-M (HLA-enabled) and monitor critical events associated with those plans within simulations. This will lead to a better understanding of the important cause-effect relationships in plans and consequently a more effective generation of courses of action.


Spin Hall effect in PdPt alloys in contact with ferromagnetic Ni80Fe20 alloys has been studied by spin torque ferromagnetic resonance technique. The spin torque spin Hall angle (ST-SHA) proves to be contributed by the interfacial and bulk SHAs. The bulk SHA is dominated by the skew scattering and reaches a maximal value for the largest randomization of Pt and Pd atoms at the intermediate alloy composition. In particular, the interfacial SHA becomes prominent for Pt-rich alloys. This phenomenon indicates the enhanced Rashba spin-orbit coupling at the interface, as Pt has a stronger spin-orbit coupling and larger z-potential gradient compared to Pd. The present work highlights the interfacial SHA and provides a pathway to improve the functionality and performance of the next generation spintronic devices.


1 Hong DK, Gutierrez K. Osteomyelitis. In: Long SS, Prober CG, Fischer M (eds). Principles and Practice of Pediatric Infectious Diseases, 5th edn. Elsevier, Amsterdam, 2017; 480– 7. 2 Jacobs RF, McCarthy RE, Elser JM. Pseudomonas osteochondritis complicating puncture wounds of the foot in children: A 10-year evaluation. J. Infect. Dis. 1989; 160: 657– 61. 3 Elliott SJ, Aronoff SC. Clinical presentation and management of Pseudomonas osteomyelitis. Clin. Pediatr. (Phila). 1985; 24: 566–70. 4 Robinette E, Shah SS. Osteomyelitis. In: Kliegman RM, Geme JS (eds). Nelson Textbook of Pediatrics, 21st edn. Saunders, Elsevier, Amsterdam, 2020; 3670–6. 5 Kremers HM, Nwojo ME, Ransom JE, Wood-Wentz CM, Melton LJ 3rd, Huddleston PM 3rd. Trends in the epidemiology of osteomyelitis: A population-based study, 1969 to 2009. J. Bone Joint Surg. Am. 2015; 97: 837–45.


The purpose of this study was to investigate the effects of sonication time and temperature on physical properties of native and cross-linked wheat starches. Starch aqueous dispersions (30%, w/w) were sonicated with an ultrasonic probe at 20kHz, 100% wave amplitude and sonication power of 100W for 5, 10, 15 and 20min at 5 and 22C. Increase in cold-water solubility, decrease in intrinsic viscosity, gelatinization enthalpy, peak, trough, setback and final viscosities of both starches were observed by increasing the sonication time and temperature. Ultrasonic treatment resulted in the formation of some fissures and cracks on the exterior of the granules as observed by a scanning electron microscope. In general, the effects of ultrasonic treatment on both starches increased with increment in processing time and temperature. The cross-linked wheat starch was more resistant against ultrasonic treatment than the native counterpart. Practical Applications: Power ultrasound has been known as an emerging technology in many food processing operations including emulsification, freezing, extraction, drying and inactivation of pathogenic bacteria on food contact surfaces. In many foods that may undergo ultrasound processing, starch and its derivatives are widely used. This research provides information on the effects of different conditions of ultrasound on native and cross-linked wheat starches as two common starches in many food products. It showed that the cross-linked wheat starch is more stable in ultrasound processed foods compared to its native counterpart.


The intercalation behavior of dodecylamine into the interlayer of layered silicates was investigated in ethanol and n-hexane, using H-magadiite, H-kenyaite, and H-montmorillonite ion-exchanged with H(+) in a HCl solution. In ethanol, dodecylamine-magadiite and -kenyaite intercalates with well ordered basal spacing were obtained in 1.5 M and 1.2 M, respectively, whereas, in n-hexane, dodecylamine-magadiite and -kenyaite intercalates were formed with well ordered basal spacing at lower concentrations of 0.9 M and 0.5 M, respectively. This indicates that dodecylamine intercalates are formed well in n-hexane. In both solvents, the basal spacings of dodecylamine-magadiite and kenyaite intercalates, were ∼48 Å and ∼53 Å, respectively, thereby showing an abnormally large increase of ∼36 Å in their gallery height. In the dodecylamine-montmorillonite intercalates, the basal spacing were significantly increased from 26.2 Å to 41.4 Å between 0.9 M and 1.2 M, resulting in an increase of 15.4 Å and 26.0 Å in the gallery height. This implies that the intercalated dodecylamine molecules have quite different molecular configurations, such as an interlamellar bilayer that is parallel or perpendicular to the silicate sheet, dependent upon the amount of intercalated dodecylamine. In ethanol, the basal spacing of the dodecylamine-kenyaite intercalates were more ordered with a decreasing temperature, yet, in n-hexane, the spacing become more ordered with an increasing temperature.


The Assistant Secretary for Elementary and Secondary Education proposes priorities, requirements, definitions, and selection criteria for Grants to Charter School Developers for the Opening of New Charter Schools and for the Replication and Expansion of High-Quality Charter Schools (Developer grants) under the Expanding Opportunity Through Quality Charter Schools Program (CSP), Catalog of Federal Domestic Assistance (CFDA) numbers 84.282B and 84.282E, respectively. We may use one or more of these priorities, requirements, definitions, and selection criteria for competitions in fiscal year (FY) 2019 and later years. We take this action to support the opening of new charter schools (CFDA 84.282B) and the replication and expansion of highquality charter schools (CFDA 84.282E) throughout the Nation, particularly those that serve educationally disadvantaged students, such as students who are individuals from lowincome families, and students who traditionally have been underserved by charter schools, such as Native American students and students in rural communities. DATES: We must receive your comments on or before May 6, 2019. ADDRESSES: Submit your comments through the Federal eRulemaking Portal or via postal mail, commercial delivery, or hand delivery. We will not accept comments submitted by fax or by email or those submitted after the comment period. To ensure that we do not receive duplicate copies, please submit your comments only once. In addition, please include the Docket ID at the top of your comments. • Federal eRulemaking Portal: Go to www.regulations.gov to submit your comments electronically. Information on using Regulations.gov, including instructions for accessing agency documents, submitting comments, and viewing the docket, is available on the site under ''Help.'' • Postal Mail, Commercial Delivery, or Hand Delivery: If you mail or deliver your comments, address them to Katherine Cox, U.S. Department of Education, 400 Maryland Avenue SW, Room 3E207, Washington, DC 20202– 5970. Privacy Note: The Department's policy is to make all comments received from members of the public available for public viewing in their entirety on the Federal eRulemaking Portal at www.regulations.gov. Therefore, commenters should be careful to include in their comments only information that they wish to make publicly available.


The invention discloses a molding manufacturing method of a nickel base alloy disc annular part, and relates to the technical field of forge pressing. The method comprises the following machining steps that an alloy ingot is heated and then taken out to be subject to upsetting, punching and chambering, a blank is machined, the above blank is heated, meanwhile, a main roller, a blank upper pressing plate and a blank lower pressing plate are preheated, the preheated blank lower pressing plate is placed in a core roller, the blank is taken out of a heating furnace, and placed on the blank lower pressing plate, the blank upper pressing plate is put into the core roller, a ring roll is started, the core roller drives the blank, the blank upper pressing plate and the blank lower pressing plate to do transverse moving motion together towards the main roller while the main roller does the rotation motion, the transverse moving motion is done while rotation motion is done, the edge of the blank begins to be thickened, finally, a cavity on the main roller is fully filled, and the disc annular part is obtained. The gradual thickening technology is adopted, and the problems that at present, the production efficiency is low, the cost is high, and the quality is poor can be effectively solved.


The purpose of this essay is to introduce and take a critical look at the emerging Ecological Restoration (ER) movement. The typical characterization of the ER movement is that it focuses on restoring ecosystems to pre-European settlement conditions, even in urban environments; thus neglecting social justice issues and alienating the disadvantaged people living in these environments. The restoration movement is often accused of redefining these spaces from a culturally and ideologically privileged standpoint—a standpoint with historical links to the exclusionary preservationist discourse of the mainstream environmental movement. On the contrary, I argue that the ER movement has closer ties to the Environmental Justice (EJ) movement than previously recognized. Toward that end, I present an ecocultural map of the actual and potential relationships between the EJ and ER movements. The map reveals boundary objects (instruments, ideas, techniques, landscapes, and actions that each culture has in common) that can serve as avenues of communication between these movements. This analysis also identifies two newly emerging cultures within the ER movement, which incorporate both restoration and social justice among their goals: the Indigenous Peoples' Restoration (IPR) movement and the Environmental Justice Restoration (EJR) movement. The IPR and EJR cultures represent examples of how the broader EJ and ER cultures can find common ground while redefining ecocultural spaces and restoring degraded ecosystems within urban and rural environments.


Microsoft TouchDevelop is a programming environment enabling users use their phones to create scripts that run on the mobile phones. This is achieved via a semi-structured editor and a programming language with several distinctive features, such as support for using smartphone hardware. In order to uncover opportunities for future tool development aimed at facilitating end-user programming of phones on phones, we have investigated the kinds of scripts that people are creating with the current tool set as well as what problems they ask for help with solving. This paper is the first to study how end-user programmers "in the wild" are programming mobile phones. In particular, no previous study has investigated the ways in which end users programmatically use mobile phones' special hardware (e.g., GPS, accelerometer, gyroscope) for practical everyday purposes. We discovered that, in essence, people are using TouchDevelop to create apps: downloadable applications with small, fairly reliable feature sets that take advantage of mobile hardware. In addition, we identified several areas for further innovation aimed at enhancing the programming tool and the online repository where users share scripts with one another.


A silicon based microphone with a 0.5 mm diam diaphragm has been developed using a combination of surface and bulk micromachining or MicroElectro Mechanical Systems (MEMS) techniques. This device is intended for high volume general purpose markets such as telephony, where cost is a key factor. In batch fabricated MEMS devices, cost is critically determined by the device size. Yet the performance standards for this microphone are set by relatively large electret condenser microphones (ECM) built in competing technologies. This paper will discuss the scaling issues involved in meeting high performance goals in a very small MEMS device. In particular, tradeoffs made to achieve high sensitivity, low noise, and unconditional stability will be discussed.


138 thyroids from citizens of St-Petersburg born in this city who died suddenly were investigated macro-, microscopically and morphometrically. The average weight was 23.72 g, being maximal at the age of 20-29 years and minimal in persons over 70 years of age. A slight increase of the weight occurred between 40 and 49 years of age. Nodular lesions were found in 8.7%. Normoplastic type of structure was observed in 84.6%. Areas of asynchronous functioning were found in all the cases. It is possible to describe age-specific normal condition of the thyroid according to morphometric data: aging results in a decrease of the follicle diameter, an increase of thyrocyte height and nuclear diameter, a decrease of Brown index, growth and thickening of fibrillar structures. There were no convincing data in favour of endemia.


Harrogate Londesborough Club was the venue for a frenetic evening of darts this week as the local chucker's saw an opportunity of summer glory in a ...


It is a key factor for large cross-section box culvert to form good slurry sleeves.Simulating tests were designed according to project that a large cross-section box culvert across down a separate interchange.Influence factors of slurry sleeve were analyzed in different soil,including positive pressure,water content and compactness.These tests prove that the best grouting pressure is the pressure just before slurry sleeves rapid diffusion.Grouting pressure increases as soil compactness increases and has no relation with water content.The test also proves that the slurry diffusion is a splitting diffusion,and splitting pressure increases with soil pressure which about two times of soil pressure.


Flufenoxuron is an acylurea insecticide which inhibits chitin synthesis. Its uptake, excretion and metabolism in larvae of Spodoptera littoralis have been measured. Larvae fed on a leaf disc sprayed at an application rate equivalent to 50 g ha−1rapidly absorbed a maximum of 20% of ingested flufenoxuron, the remainder being voided in the frass. Excretion of absorbed compound was slow, with a 50% excretion time of approximately 20 h. Flufenoxuron was equally effective as an insecticide by topical application or ingestion. Following topical application, a total of 11% of the dose had penetrated into the body within 24 h. Of this 11%, half had travelled to the gut so that the rest of the body tissues contained no more than 6% of the toxicant dose. The concentration of flufenoxuron in the body tissues was maintained for at least 24 h, the surface residue probably acting as a reservoir. The compound was metabolically quite stable. Following topical application the 6 % of the applied dose which was absorbed into the body was still 92% as unchanged flufenoxuron 24 h after application. The enhanced toxicity of flufenoxuron to S. littoralis compared with earlier acylureas can probably be attributed to its slower metabolism and reduced excretion.


In clarity and testability, Doyle's theory is a considerable advance, but it is largely refuted by the facts. None of his three conditions is necessary for the rise or survival of empire as he defines it. First, not only highly differentiated societies become imperial metropoles. Doyle concedes (pp. 105ff.) that the early Islamic empires were won by tribal (i.e. undifferentiated) societies; the Persian empire was patrimonial, that of Charlemagne was feudal. Neither is domestic unity required. Doyle himself, having repeatedly insisted that unity is essential, argues that Third Republican France pursued empire as an answer to political disunity and weakness (pp. 314-18). Second, not only undifferentiated or poorly integrated peripheries lose "effective political sovereignty" to other powers: the Ionian Greeks of Asia Minor were conquered and ruled by the lessdifferentiated and less-integrated Persians; the Carthaginians were at least as socially advanced and cohesive as the Romans; the East European societies were hardly less articulated or integrated when the Soviet one to which they lost effective sovereignty after World War II. Third, unless "transnational extension" is defined tautologically (as one might infer from Doyle's discussion at pp. 129-130), it, too, is not required. The Spaniards in Mexico and Peru had no prior contacts with the peoples they conquered; and ancient imperialists, bent on extermination or enslavement, often developed few.


Aluminosilicates, gallosilicates, and indosilicates with the ZSM-5 type structure were prepared by the "Atom-Planting method". The introduction of metal cations into the framework of highly siliceous ZSM-5 zeolites was confirmed by IR and unit cell volume measurements. The acidic properties of these metallosilicates were examined by pyridine-IR and NH3-temperature programmed desorption spectroscopies. The increasing order of the acid strengths of the metallosilicates is indosilicate


Abstract In this paper the plans for the proposed sample census of the Sudan are presented. The difficulties due to local conditions and customs are described, and ways and means of overcoming them are suggested.


Abstract For teaching practice to be useful, educational materials must be thoroughly evaluated prior to use. In this study, teachers evaluated open educational resources (OER) created for a European Commission Horizon 2020 project called DIALLS ('DIalogue and Argumentation for cultural Literacy Learning in Schools'). Considering research on how OER are evaluated, we were interested in learning (1) how teachers perceive their application, content, design, value and sustainability and (2) what other aspects teachers find important when evaluating OER. After analysing quantitative and qualitative data, we found that aspects facilitating self-regulated use were rated most highly and mentioned most often. Teachers additionally valued adaptable materials offering opportunities to reflect their teaching practices. Future research may benefit from evaluating OER based on 'affordance' aspects — aspects that allow teachers to adapt the materials in a self-regulated way and reflect on their teaching.


Chapter 1. The Capitalist Schema Chapter 2. The Capitalist Thing Chapter 3. Money Chapter 4. The Temporality of Money Chapter 5. The Abstractions of Money Conclusion


The vti has carried out a number of field trials on commission by the national road administration in order to investigate the durability to mechanical abrasion of a number of geotextiles used in strengthening a road, damaged by frost. At the same time, the effect on the transport of water of geotextiles lying beneath frozen layers has been studied in field and laboratory investigations. The field trials have been carried out on test stretches laid on road 1068 in the province of vaesternorrland in 1982. The laboratory tests have been carried out at the vti during the period 1982-1984. The field trials took place mainly during 1982-1985, but a final inspection of the condition of the geotextiles in the road was made during summer 1988. With regard to durability, the field trials, which covered 10 geotextiles, have shown that on the test stretches with a covering layer more than 20 cm thick, most of the geotextiles tested which had been in place for 6 years remained intact. From other similar tests it has been found that geotextiles extracted from test stretches with 10 cm overlying layers were completely worn out. Also some geotextiles that had been in use for 3-3+ years and with 20-25 cm thick layers on top showed abrasion damage in the form of fabric breaking away. Certain differences in durability were found in this study. The effects of water transport in frozen layers on top of geotextiles which were found in laboratory investigations could not be demonstrated in field trials. In laboratory tests of new geotextiles of non-woven type and woven type with ribbon fibres, it was found that these had a capillary cutoff effect when the layers above the geotextiles froze. However, it was found that this effect was sensitive to bridging of fine material and required that the geotextiles remained intact. It is therefore doubtful whether the capillary cutoff effect observed can be utilised in such cases where the design requires a reliable capillary cutoff effect unless measures are taken to prevent damage to the geotextiles and infiltration of these by fine material.


ABSTRACT For the purpose of using coal gasification coarse slag, carbon/ash separation by flotation is necessary. In this work, kerosene and dodecylamine polyoxyethylene ether (AC1202) were combined to create a composite collector known as AK, which was used in flotation experiments. The findings reveal that when the dosage of the AK collector was raised to 14 kg/t, the tailings ash reached as high as 83.76% and the combustible recovery increased by 69.84% to 81.42%, which is almost 28.62% higher than that of kerosene. The characteristics of various collectors, the strength of the adsorption between various collectors and particles, and the variation in particle hydrophobicity after the action of various collectors are used to elucidate the mechanism of the improved flotation effect with composite collectors. A new technique for separating the carbon and ash from coal gasification coarse slag is provided by the use of the AK collector. GRAPHICAL ABSTRACT


Atomistic calculations are performed to study defect energetics in ZnGeP2 where two‐ and three‐body interatomic potentials are used to simulate the perfect lattice. Formation energies for native ionic defects and binding energies for some of the electronic defect complexes are calculated. The dominance of antisite defect pairs, ZnGe+GeZn, is predicted in the lattice. However, the defects controlling the spectroscopic properties would seem to be associated with vacancies. For the EPR‐active acceptor center, the hole is found to be localized near the zinc vacancy rather than near the zinc antisite (ZnGe). The calculated results suggest that the reported Hall effect and the photoluminescence data are compatible with the existence of two acceptors in the lattice (in a three level model) where one is significantly shallower, experimentally by 0.27 eV, in reasonable agreement with the calculated difference of 0.37 eV.


This study has the purpose to search for the relationship among healthy family relationship, self-esteem and depression through path analysis, in order to analyze the positive cause and effect relationship, and to reveal the political implication. For this purposes, I analyzed data targeted on 317 numbers of middle school students and high school students in Gwangju. Frequency analysis, technique statistics analysis and correlation analysis on the collected data are executed by using SPSS statistics program, and path analysis was executed by using AMOS statistics program. The results can be summarized as follows. Firstly, teenager's depression showed negative correlation on the healthy family relationship and self-esteem. Secondly, healthy family relationship had meaningful effect on self-esteem, and self-esteem also had meaningful influence on the depression. Thirdly, healthy family relationship had meaningful effect on depression, and it was confirmed that self-esteem had a partial mediating effect between healthy family relationship and depression. The results of the research suggest that the intermediation to improve healthy family relationship and self-esteem is needed as a substitutional strategy to prevent and reduce the depression of teenagers.


Thank you very much for downloading fabricating the keynesian revolution studies of the inter war literature on money the cycle and unemployment. As you may know, people have search hundreds times for their favorite books like this fabricating the keynesian revolution studies of the inter war literature on money the cycle and unemployment, but end up in malicious downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they juggled with some harmful virus inside their desktop computer.


The potential anti-parasitic of lees from several wine varieties was investigated using an in vitro anthelmintic assay using Haemonchus contortus eggs. The most effective lees variety was further investigated in lambs in two trials. In Trial 1, 60 sheep was pasture grazed as one mob and allocated to one of three groups (n = 20): water drenched; drenched with the anthelmintic Matrix, and daily drenched with 100 mL/animal Pinot noir (PN) lees. In Trial 2, 80 lambs were grazed as one mob and assigned to four treatments (n = 20): Pasture only (Control); Pasture plus lucerne pellets; Pasture, lucerne pellets and drenched with Matrix; Pasture, lucerne pellets and wine lees. In both trials, fecal egg count (FEC) and live weight were measured weekly. PN lees displayed positive in-vitro anthelmintic activity. In Trial 1, lees provided insignificant (7%) increase in cumulative liveweight gain relative to Control (P >0.05). In Trial 2, the overall mean daily gain (g/day) was not different with lees feeding but slight increased (26.6%) following drenching with Matrix (P >0.05). Lees, at the concentration used in this trial of 460 mg tannin/day/animal, did not offer a reliable stand-alone anthelmintic control.


The characteristics and functions of the electronic control pump tube nozzle system used for 240/275 diesel engine are presented.The effects of the pump tube nozzle system on diesel engine's performances are also proposed.


With the high-power light emitting diode(LED) turning on,the LED total luminous flux and luminous efficiency will be significantly decreased with the increase of the internal PN junction temperature.Using pulse-current source to drive LED can effectively reduce heat accumulation problem.The LED total luminous flux decreases with the increase of time in the DC mode,but it does not change in the pulse mode.In addition,at the same current value,the current efficiency of LED in pulse mode is higher than that in the DC mode,reducing the loss of efficiency of the rise in temperature.


This thesis explores the development of major themes in Martin Boyd's AngloAustralian novels, that is, The Mont forts, Lucinda Bray ford and the Langton sequence. Examination of these novels shows that, though constantly drawing on Boyd's family background and his personal experience in both Australia and Europe, they are not repetitive, but demonstrate a trend towards growing maturity in writing. The first chapter starts with the examination of The Montforts, arguing that the writer focuses attention on the history of a family rather than on the study of character. Through the depiction of the migration of the Montforts and of the impact of the migration on the family and their descendents, emerge Boyd's initial themes of "the complex fate", his hatred of the middle-class and his correlation of spiritual and material well-being. Chapter two concentrates on Lucinda Brayford and argues that Boyd shifts his interest from the history of a family to the study of character. Through the description of the searches of Julie, Lucinda and Stephen for a value in life, Boyd's themes go beyond those of The Montforts to encompass the ideas of the nature of happiness, the meaning of life and the two worlds: England and Australia. The Langton sequence is examined in four chapters. In these chapters, it is argued that the Langton novels seem to combine the merits of both The Montforts and Lucinda Brayford. With the exception of When Blackbirds Sing, the Langton books use Guy Langton as narrator-persona, a device which makes Boyd's themes fuller and more complex. The themes of class, the meaning of life, the nature of happiness and the two worlds find their fullest expression here. Chapter three focuses on The Cardboard Crown, in which Boyd concentrates on the quest for happiness on earth through Alice's search for values. The fourth chapter is concerned with Outbreak of Love, in which the writer continues his argument in The Cardboard Crown and illustrates where happiness might lie through the story of Diana. Chapter five concerns Boyd's restatement through the depiction of Dominic in .4 Difficult Young Man of the cultural issues concerning Europe and Australia


Patients with upper limb and hand burn suffer from a higher pain perception due to higher density of nerve endings and larger cortical representation compared to other regions. This unfortunately leads to reduction of movement, increasing edema and stiffness. This initiates a vicious cycle leading to prolonged morbidity and repeated interventions. In our burn centre we are routinely practicing regional supraclavicular analgesic blocks for hand burn. We have found this technique immensely beneficial in pain relief, promoting early healing with restoration of range of motion (ROM) and functional recovery.


Foreword Preface and user's guide Drugs A to Z Safe drug administration Photogallery of common tablets and capsules Drug classes Vitamins and minerals Herbs and supplements Appendices Index


Summary Liver cells from normal C3H/HeDub mice have reduced activities of mitochondrial succinate dehydrogenase (EC 184.108.40.206), malate dehydrogenase (EC 220.127.116.11), and adenylate kinase (EC 22.214.171.124) after being exposed to 10μg Escherichia coli 0127:B8 lipopolysaccharide (Westphal preparation) per milliliter of culture medium lacking serum for 2 hr at 37°C. Liver cells from endotoxin-refractory mice, whether rendered resistant by prior treatment with LPS, or from the genetically resistant C3H/HeJ mouse, exhibited normal mitochondrial activity after being exposed to LPS. Isolated mitochondria from endotoxin susceptible and endotoxin-refractory mice were sensitive to LPS indicating that resistance is a cellular and not an organellar attribute.


The brain GABAA receptor (GABAAR) is a key element of signaling and neural transmission in health and disease. Recently, complete sequence analysis of the recombinant GABAAR has been reported, separation and mass spectrometrical (MS) characterisation from tissue, however, has not been published so far. Hippocampi were homogenised, put on a sucrose gradient 10–69% and the layer from 10 to 20% was used for extraction of membrane proteins by a solution of Triton X‐100, 1.5 M aminocaproic acid in the presence of 0.3 M Bis‐Tris. This mixture was subsequently loaded onto blue native PAGE (BN‐PAGE) with subsequent analysis on denaturing gel systems. Spots from the 3‐DE electrophoretic run were stained with Colloidal Coomassie Brilliant Blue, and spots with an apparent molecular weight between 40 and 60 kDa were picked and in‐gel digested with trypsin, chymotrypsin and subtilisin. The resulting peptides were analysed by nano‐LC‐ESI‐MS/MS (ion trap) and protein identification was carried out using MASCOT searches. In addition, known GABAAR‐specific MS information taken from own previous studies was used for searches of GABAAR subunits. β‐1, β‐2 and β‐3, θ and ρ‐1 subunits were detected and six novel phosphorylation sites were observed and verified by phosphatase treatment. The method used herein enables identification of several GABAAR subunits from mouse hippocampus along with phosphorylations of β‐1 (T227, Y230), β‐2 (Y215, T439) and β‐3 (T282, S406) subunits. The procedure forms the basis for GABAAR studies at the protein chemical rather than at the immunochemical level in health and disease.


There are general questions about what art may contribute to philosophy and what philosophy may contribute to art, and we may narrow those questions so that they deal with philosophy and film specifically. This paper will explore several dimensions of this general theme. First, I will suggest that a specific theory of judgment drawn from the Columbia Naturalist tradition provides a valuable conceptual context for addressing the questions; second, a case will be made to support the idea that though art in general and film in particular may have philosophical dimensions, and that though philosophy may have aesthetic dimensions, we cannot expect art, including film, to be philosophy anymore than we can expect philosophy to be art; third, and in light of the first two, it becomes important to understand the nature and extent of the philosophical dimension of art and film and of the aesthetic dimension of philosophy. In brief, a case will be made in support of the view that for the most part philosophy is a form of assertive judgment that may also function exhibitively, and that art and film on the whole are forms of exhibitive judgment that may also have an assertive dimension. This distinction allows us to understand the limits each has with respect to the other while at the same time that each can to some degree have characteristics of the other. This point can be particularly helpful with respect to art forms that have a narrative character, which is to say to literature, film, and related works of art, because narrative expressions can more easily than the plastic or musical arts, though misleadingly, give the impression they are making an argument. Film does not argue, at least not in any literal sense; it portrays. In its portrayals, however, it may exhibit matters of philosophic interest and even importance, and it may make a case, even a sustained and complex case, for an idea.


An equivalent definition is given from the perspective of group theory.For any given G(G is a subset of R),which is not a cyclic group,the periodic function with G as periodic set is constructed,and it is without minimal positive period.Properties of periodic function without minimal positive period is discussed.


Abstract : This paper presents reflectance data for leaf and bark samples taken from a big-leaf aspen tree located near Orono, Maine. Total hemispherical directional reflectance measurements were made for several angles of incidence between 20 and 80 deg. and over the 0.3 to 25.0 microns spectral region. Since the leaves are translucent, transmittance measurements were also made. Bidirectional reflectances were measured for incident angles of 20, 40 and 60 deg. at wavelengths of 1.3, 4.6 and 10.0 microns. In addition, some reflectance data from a concrete runway and adjacent grasses are presented.


Abstract In this paper we investigate the relationships between job search, commutes to work, and metropolitan decentralization of employment among young whites and blacks. We investigate the effects of travel costs (based partly on access to auto travel) and metropolitan decentralization on distances traveled while searching and working, unemployment durations, and wages. High travel costs and reduced travel distances appear to raise unemployment durations and lower wages for blacks by modest amounts. Furthermore, blacks and inner-city residents do not offset greater metropolitan decentralization with greater distances traveled. Both results are consistent with persistent spatial mismatch.


SUMMARYSmall colonies of emerged bees were kept in confinement, and fed fresh pollen, or pollen two years old supplemented with: nothing, pantothenic acid, 20% dried brewers' yeast, 20% vitamin-free casein, casein plus pantothenic acid. The number of sealed brood cells in these colonies (in the above order) was 8·9, 1·0, 2·8, 4·4, 5·6, and 5·8 times the number in the colonies fed old pollen alone. Deterioration of proteins and of pantothenic acid is thus partially responsible for the inferior value of stored pollen for brood rearing.


Gauging γδ T Cell Groupings See article p. 1449 Hostile NK Cells Educate Themselves See article p. 1506 HDAC3 Helps Teenage T Cells Mature See article p. 1578 Lysosomes and Lyme Arthritis See article p. 1647 Helping T Cells Remember Chlamydia See article p. 1665 Incognito IL-1R Antagonist See article p. 1705


Cancellation of the agricultural tax in rural,it reduce the burden on farmers and increase the income of farmers. But it has not resolve the deep-rooted contradictions of the agriculture and rural's development. The incoming gap is widening between urban and rural residents, the efficiency is reduced in the use of land. The debt of rural、the supply of pubic goods and the basic medical insurance is need to resolve. We should have comprehensive reform in the rural, from establishing a long-term mechanism to increase farmers income、improve the land-use system、gradient and scale immigration、ensuring of the population in absolute poverty and so on to, to improve the social and economic development in west rural.


The present invention relates to a raditional Chinese medicine preparation for treating postpartum abdominal pain, which takes more than 10 traditional Chinese medicines of twotooth achyranthes root, yanhusuo, cassia bark, nutgrass galingale rhizome etc. as the raw materials. The invention has the effects of nourishing blood, benefiting qi, relieving spasm and stopping pain. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine preparation for treating postpartum abdominal pain. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.


In this article, we present an implementation of a brain-computer-musical interface (BCMI), based on the Enobio-8 EEG device, a commercial headset that contains eight or more electrodes and a 3D accelerometer. We have developed Enobio2OSC, a software that receives data from the Enobio via TCP/IP, calculates the appropriate frequency bands, and sends data out using the OSC protocol. We also provide two examples of the potential usage of this BCMI, the first based on the phenomenon known as alpha synchronization, while the second is based on mental arithmetic. We also developed Max patches that receive raw data and the band power values along with the accelerometer data via OSC and converts them into musical parameters. This BCMI allows users to control music by closing and opening their eyes and moving their heads or by mental arithmetic, and it has proven to be effective for a user with Locked-in Syndrome.


A promising approach to optimize coverage and capacity in the cellular network is the adjustment of antenna azimuth orientation and tilt. Tuning both antenna parameters without considering a realistic user traffic distribution in the network might result in a cellular layout having cells covering large areas when small areas are expected and vice-versa. In real life scenarios, mobile users are distributed in the network where some areas are concentrated more than others. Therefore, the adjustment of antenna parameters should yield a cellular layout that is compatible with the distribution of the user traffic in the network. In this work, a new mathematical model for user traffic is presented in coverage and capacity optimization. The antenna azimuth orientations and tilts are configured jointly for a predefined user traffic using an optimization procedure based on Taguchi's method applying nearly orthogonal array. The proposed model for user traffic is validated in long term evolution downlink where results show that coverage and capacity are optimized and the resulting network layouts are fully compliant with the assumed user traffic distributions.


Objective: This study investigated the association between maternal depression and maternal–fetal attachment (MFA) and whether contextual variables such as social support and fathers' presence moderated this association. Background: Adolescent pregnancy is associated with multiple risk factors that may compromise the relationship between mothers and their infants. However, this relationship starts during pregnancy, being affected by aspects such as social support and maternal depression. Method: Forty-nine adolescent mothers (Mage = 16.49 years; SD = 1.58) participated in the first wave of a longitudinal study which investigated social factors associated with parenting characteristics of Brazilian adolescent mothers; 65.3% reported they were cohabiting (married or living together) with the infant's father. Results: Hierarchical regression analysis revealed that higher levels of social support were associated with greater MFA. Marital status was not significant. The association between maternal depression and MFA was significant for those participants who reported high levels of social support, but not for those participants who reported low levels of social support. Conclusion: Social support emerged as a key variable moderating the association between maternal depression and MFA. Contrary to expectations, maternal depression did not have a negative association with MFA, and further studies are needed to understand how social support promotes MFA, in the presence of other vulnerabilities, such as maternal depression.


Human prostate cancer is notable for its high number of somatic copy number alterations (CNAs), which include both focal and broad arm-level amplifications and deletions. Up to 90% of prostate tumors harbor aberrant CNAs, and genomic deletions affect about 40% of these tumors. Many chromosomal deletions are highly recurrent and occur in more than 10% of prostate tumors, including 8p (40~50%), 6q14-16, 10q23, 13q14, and 16q22-24 (20~30% each). Most of these deletions are large, often including hundreds of genes. Notably, several large deletions, including 6q14-16 and 16q22-24, are significantly associated with poor patient outcomes, suggesting that these large chromosomal deletions play a functional role in prostate tumorigenesis, and highlighting the critical need for elucidation of the mechanisms underlying large-deletion driven tumorigenesis. However, due to the limited cloning capacity of targeting vectors and the rarity of on-target homologous recombination events in traditional gene-targeting technology, modelling large chromosomal deletions has proven highly challenging, and the role of such lesions in tumorigenesis has therefore been significantly understudied. Here, we developed an innovative approach to engineering the chromosome over large genetic distances through CRISPR/Cas9 technology in both mouse embryonic stem (ES) cells and human prostate cancer cells. Upon completion of the desired genome edits, the resulting mouse ES clones make possible the creation of conditional knockout mice that accurately mimic prostate cancer-associated large deletions, while the engineered human cancer cell clones serve as an indispensable in vitro model to validate the biological relevance of large chromosomal deletions in prostate tumorigenesis. Further characterization of the human prostate cell line bearing 10q23 deletion revealed that 10q23 loss conferred RWPE1 cells growth advantage. The development and characterization of these in vivo and in vitro models will contribute greatly to the implementation of precision oncology research, open new opportunities for modelling human diseases associated with large chromosomal deletions, and lead to novel insights into the biology of prostate cancer-associated large deletions, which will facilitate the identification of deletion-specific vulnerabilities that can be exploited for prostate cancer treatment.
 Citation Format: Jinjin Wu, Chen Wu, Joel A. Lawitts, Cheryl B. Bock, Jiaoti Huang, Ming Chen. Engineering large chromosomal deletions to advance precision oncology for prostate cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 316.


Although reclamation can increase land area, it decreases natural shoreline, coastal wetland and fishery resources. It remains a contradiction between the utilization of reclamation and protection of marine resources. The effective method to judge reclamation impact on marine resources is of great importance. Based on results of three rounds expert investigation, this paper established a system to make the judgement. Two steps were taken: using Delphi method to obtain the weight of qualitative and quantitive evaluation indicators, using SPSS statistical software to get reliability test results, which show that expert opinions are in well agreement. The indicator weights were finally gived.


Characterization of atmospheric aerosols using ground based lidar measurements de-pend upon accurate attribution of the sources of the aerosol. Often this is achieved by selecting specific altitudes and times representing interesting features in the lidar profiles and then running back trajectories from those locations. This paper describes a method to do this in a continuous way by using ensemble trajectories from the HYSPLIT or particle dispersion modelling from FLEXPART. The authors had presented elements of this methodology in earlier publications and have now presented them in a consoli-dated way. They give examples showing the application of the methodology as well as give an assessment of the representativeness of time limited ground based lidar observations. This is an interesting paper and may have ramifications for other applications.


Neapolitan pizza is very popular worldwide and is registered on the traditional specialties guaranteed (TSG) list. This study was aimed at identifying the cradle-to-grave carbon footprint (CF) of a medium-sized pizza restaurant serving in situ or takeaway true Neapolitan pizzas conforming to the Publicly Available Specification (PAS) 2050 standard method. An average CF of ~4.69 kg CO2e/diner was estimated, about 74% of which was due to the production of the ingredients used (with buffalo mozzarella cheese alone representing as much as 52% of CF). The contribution of beverages, packaging materials, transportation, and energy sources varied within 6.8 and 4.6% of CF. The percentage relative variation of CF with respect to its basic score was of about +26%, +4.4%, and +1.6% or +2.1%, provided that the emission factor of buffalo mozzarella, fresh cow mozzarella (fiordilatte), Grana Padano cheeses, and electricity varied by +50% with respect to each corresponding default value, respectively. The specific carbon footprint for Marinara pizza was equal to ~4 kg CO2e/kg, while for Margherita pizza, it was up to 5.1, or 10.8 kg CO2e/kg when topped with fresh cow or buffalo mozzarella cheese. To help pizza restaurant operators select the most rewarding mitigation strategy, we explored how CF was affected by more sustainable buffalo mozzarella cheese production, lighter and reusable containers for beer, mineral water, and main fresh vegetables, newer diesel-powered vans, less air-polluting electric ovens instead of traditional wood-fired ovens, as well as renewable electricity sources.


The invention relates to the technical field of equipment part processing equipment, in particular to an automatic modularized turning assembly line which comprises a height-adjustable support. A rod lifting mechanism assembly, a rod longitudinal-conveying mechanism, a rod taking and transverse-conveying manipulator assembly, an adjustable buffer feed hopper assembly, a lathe spindle rear-feeding and positioning device, a lathe tool rest dragging manipulator, a pneumatic lathe discharging and collecting device assembly, a three-shaft automatic taking and transverse-feeding manipulator assembly, a second circulating rear-feeding buffer feed hopper assembly, a second circulating lathe spindle rear-feeding and positioning device, a second circulating lathe tool rest dragging manipulator device, a second pneumatic circulating lathe discharging and collecting device assembly, a third circulating three-shaft automatic taking and transverse-feeding manipulator assembly and a turning finished product longitudinal-conveying mechanism. The automatic modularized turning assembly line is reasonable in structural arrangement, and production efficiency is greatly improved.


Implementation of conception of public sphere is presented in this paper. The conception is understood as an arena of social contract for ways of social interaction. Mass media organize the social interaction and form various models of social practice which answer the of market-oriented reforms.


According to our country railroad passenger transportation special line in Wuhan-Guangzhou experiment segment engineering construction of demand,to the Mass Rapid Transit bridge railing mechanization production the craft and production line carried on a research.Pass a related production craft experiment,to currently domestic widespreadly adopt of the concrete product produced a basic craft to carry on index sign examination and data contrast analysis,the innovation ground put forward to establish a pair of effect production craft,then prepare to make piece in the middle of sprinkling and noting the forerunner go to prepare to flap actually and promise the airtight solid degree of finished product and leave heart to model improvement prepare the external appearance quality of making the piece.Combining an engineering construction at the same time is actual and developed by oneself a Mass Rapid Transit bridge railing mechanization production line,and introduced the main device of mechanizing the production line,include to separate pillar and sign a pillar,arm-rest production line among them,the main equipments included to leave heart to model machine and flapped a solid set,molding tool to dismantle to pack machine tool etc.,and guaranteed the production line control of product quality.Pass to practice an usage,Mass Rapid Transit bridge railing mechanization the production line have to produce an efficiency Gao,in brief and easily operate,credibility stability,maintenance expenses low etc.advantage.The product produced by the production line can satisfy railing structure to be subjected to dint and use function and have shape beauty,quality stable dependable characteristics.


This paper presents an analysis of water supply and sanitation (WSS) services in Brazil, and focuses on the broader concept of "basic sanitation" used in Brazil. The analysis departs from the assumption that there is a need to combine appropriate technological approaches with a public-policy perspective that recognises the relevance of the political dimension. I adopt the concept of "systemic conditions" as an analytical tool to integrate the structural factors and processes that influence and even determine the development of WSS services. A brief description of the sector's historical evolution is included, where I identify key obstacles and opportunities facing the sector. The article examines the current state of access to the services, including the political, institutional and legal aspects, and highlights some of the challenges ahead. It shows that, although the Brazilian WSS sector has achieved important advances, there are significant deficits in several areas that need to be addressed. Closing this gap will require the adoption of a new institutional framework oriented at the universalisation of the services based on the principle of equity, and the recognition and understanding of the existing asymmetries in service provision. Moreover, it will also require an in-depth understanding of the systemic conditions and of the tensions and contradictions characterising the interrelations between the different actors, particularly in the face of the resistance to change already experienced in relation to ongoing institutional changes in the sector.


This paper describes the power of storytelling in the context of an Indigenous youth collective, whichgathers each week to share their lived experiences and learn song, dance, and lessons through story. Ibegin with my own life narrative followed by an exploration of how the intergenerational transmissionof historical trauma has left many Indigenous youth searching for a connection to their culture. I thendiscuss research that reveals the importance of cultural continuity, self-determination, and engagementin the community to the healing journey of Indigenous youth. Next, I consider oral storytelling as onemethod of knowledge delivery, utilized by Indigenous Nations for thousands of years, that seamlesslyblends cultural learning and thus connection to identity. I detail the creation of a Youth StorytellingCircle which centres teachings from the Stó:lō, Haida, Nisga'a, Salish, and Popkum Coast Salish Nationssurrounding the shores and rainforests of what is now British Columbia. I conclude with reasons whyengaging youth in their wellbeing through traditional practices is of high importance to us all as Indigenouscommunity members.


We prove a result about reducibility behaviour of Thue polynomials over the rationals that was conjectured in [6]. Special cases have been proved e.g. by Müller in [6], Theorem 4.9, and Langmann ([5], Satz 3.5). The proof uses ramification theory to reduce the assertion to a statement about permutation groups containing an n-cycle. This statement is finally proven with the help of the classification of primitive permutation groups containing an ncycle (a result which rests on the classification of finite simple groups).


Isometric force generation, the result of the interaction of an actively shortening contractile element (CE) with a passive series elastic component (SE), has been analyzed in heart muscle using th...


The purpose of this analysis is to propose a theoretical-critical-literary approach and from a post-historical edge to the poetic work Vírgenes del Sol Inn Cabaret: vien benidos a la máquina welcome to the tv by Alexis Figueroa (1986). This approach leads us to understand its production from three keys: endoculturation, literary competence and endotextuality. All of them give an account of the cultural framework in which they are immersed, writer and / or reader, and must be found in the work, which is rather an endotextual synthesis of endoculturation and literary competence.


Pumice particles represent the basic "ingredient" of many large explosive eruptions and form as a result of magma fragmentation inside the conduit. At the onset of eruption, fragmental pumices are expelled at high velocity from the crater by the overpressure of gas liberated on explosion. The resulting multiphase flow is forced through atmosphere by a variety of transportation mechanisms and pumices eventually decouple from the gas flow, settling down to form pyroclastic deposits. Here we propose new experimental data of terminal velocity together with a quantitative shape analysis of a wide range of pumice particles. The resulting model allows predicting the terminal velocity of pumice by means of easily measured particle characteristics, with an average error of 12%, which compares favourably with previous models.


Metaphysics had originally belonged to the field of speculative or theoretical philosophy. Kant turned away from this traditional thought to attempt to establish metaphysics in the field of practical philosophy. He tried to pave the way for a changed form of metaphysics, and it was because he found it impossible to enter into the world of intelligence, the ultimate issue of metaphysics, by means of speculative metaphysics. Kant called the new metaphysics established in the field of practical philosophy 'metaphysics of morals' and it is to assert that we can enact law concerning the use of will independently through the practical use of reason and that we can form moral relationship with the world through the moral law we legislated ourselves. It also emphasizes that by forming such relationship, in other words, by living an ethical life, we can be a member of the world of intelligence. If we are to choose moral imperative, it means that we choose to become our unalienable selves. It also means that we, withdrawing our glance that has been turned toward worldly success or happiness, come to meet ourselves face-to-face in earnest in the face of the unlimited and categorical imperative. It is the intelligent being that we are confronted with at this very moment.


Purpose – The purpose of this paper is to examine the interaction of pricing strategies with other aspects of launch, in particular, timing, logistics/inventory strategy, and coordination with support organizations, and the effect on profit and competitive performance.Design/methodology/approach – The paper presents an empirical study of 215 recent new product launches, focusing on pricing and other strategic and tactical launch decisions and the resulting profitability and competitive performance. Clusters of new product launches are identified and the profitability and competitiveness of each cluster are discussed.Findings – The paper finds that some clusters are related to greater success than others. The most profitable and competitively successful cluster contained launches supported by solid market research and marked by good timing decisions. By contrast, the least profitable/successful cluster were higher price launches unsupported by adequate research.Research limitations/implications – The study...


Based on the investigation and statistical analysis on the role and impacts of Chinese Wushu among the variety of international martial arts styles and fighting arts demonstrates,this study proposed that,during the procedure of introducing Wushu to the world,it is necessary to utilize the good reputation and the popularity of Chinese Wushu in the world,continue to develop the effects of the movie and TV in popularizing Chinese Wushu.It is also essential to address the interflowing and research on practice, fighting characteristics and cultural characteristics of Chinese Wushu techniques.It is suggested that we should maintain and stress the features of practice and fighting characteristics in Chinese Wushu techniques during the process of establishing the model and competitions of Chinese Wushu.It is concluded that we should enhance the connection with international Wushu issues,organizations and colleges so as to interpenetrate Chinese Wushu into the curriculum of international colleges and improve the quality and the level of the Wushu.


Introduction: End stage Renal Disease refers to permanent, irreversible loss of renal functions due to variety of underlying disorders. The condition is quite prevalent in our part of the world. The occurrence of Restless legs syndrome (RLS) in such patients, especially those on hemodialysis, surpasses that in the general population. RLS significantly blemishes their quality of life. The syndrome has subtle and nonspecific symptoms which are commonly neglected in dialysis centers. The study aims to determine the frequency of restless leg syndrome in patients of advanced renal disease.
Methodology: A Cross Sectional Study conducted at Department of Medicine, Mayo Hospital Lahore from Dec 2018 to June 2019 (6 months). Patients of 20-80 years of age and of both genders, diagnosed as ESRD for ≥3 months were enrolled and evaluated for RLS. The condition was diagnosed as per International RLS Study Group (IRLSSG) criteria. The demographic data (age, gender, BMI and duration of symptoms) was recorded. History of smoking, alcohol use and chronicity of disease was also noted. Mean and percentages were calculated. Chi-Square test was applied. p-value of ≤0.05 was taken as significant.
Results: Total of 75 patients were enrolled. Males were 54 (72.0%) while 21 (28.0%) were females. Mean age was 47.3±13.1(22-73) years. RLS was observed in 29 (38.7%) cases. Age, gender, duration of illness, smoking and alcohol consumption had no significant association with RLS (p values 0.642, 0.669, 0.208, 0.245, 0.565, 0.745) respectively.
Conclusion: Restless legs syndrome is frequently encountered condition in ESRD patients.


Few-shot object classification is the task of classifying objects in an image with limited number of examples as supervision. We propose a one-shot/few-shot classification model that can classify an object of any unseen class into a relatively general category in an hierarchically based classification. Our model uses a three-level hierarchical contrastive loss based ResNet152 classifier for classifying an object based on its features extracted from Image embedding, not used during the training phase. For our experimentation, we have used a subset of the ImageNet (ILSVRC-12) dataset that contains only the animal classes for training our model and created our own dataset of unseen classes for evaluating our trained model. Our model provides satisfactory results in classifying the unknown objects into a generic category which has been later discussed in greater detail.


Disruption era demands human to be able to compete and to innovate. Demands in being competitive stimulate the ambitious, aggressive, and less empathy attitude if it is not based on the good moral and spiritual. Developing children' empathy by spiritual values can be done through education since it is as the transformation that the function is to create noble, knowledgeable, and modern individuals. School teachers and counselor can take parts in developing the service strategy to develop empathy in children as the social and religious creature. This was a literature study aimed at reviews the spiritual counseling with Al-Maun theological based symbolic model technique. The data of this study were collected through documentation study from relevant journals, book, and proceedings which analyzed by using descriptive qualitative. The result of the study showed that Al-Maun theological-based symbolic model technique of spiritual counseling is assumed to be a strategy for developing children' empathy. The result of the study can be a suggestion for elementary school counselors in developing children empathy based on the spiritual values.