The Caurapancāśikā is a short Sanskrit poem about remembered love. It can, however, be read as a poem about poetry: its ascription to the poet Bilhaṇa, the stories about its composition, and the choice of metaphors in the text invite us to think of the beloved as an embodiment of literature (kāvya), and the poet's constant return to her in memory as a model of the kind of relationship that participants in a literary culture (sahṛdayas, rasikas) have to literature. The main implications of this reading are the attribution to literature of the qualities of the beloved—and vice versa—and the characterization of literature as an inalienable possession in the "storehouse of Sarasvatī in the heart," which memory keeps safe from the dangers of political life to which it is constantly exposed.


The invention relates to a muscle-powered tricycle, comprising a frame and a cabin attached to the frame. According to the invention, the cabin is essentially closed and surrounds both the driver and the passengers and a method comprises producing the cabin in polythene. The invention further relates to a muscle-powered tricycle, which is characterised to a high degree in that said tricycle is compact and comprises a protective structure, protecting both passengers and driver.


The purposes of this study were (1) to implement the results of E-Module Development in Operating System Subject with Problem Based Learning Model (Study Case: Grade X of TKJ at SMK Negeri 3 Singaraja), (2) to determine the student's response of E-Modules Development in Operating System Subject with Problem Based Learning Model (Study case: Grade X of TKJ at SMK Negeri 3 Singaraja). The type of this study was using Research and Development (R&D) with applied the method ADDIE model. The target of this study is the students in Computer and Network Engineering Grade X at SMK Negeri 3 Singaraja on 2016/2017. The response of the students toward the e-modul development, was obtained by using questionnaire method. Implementation result of E-Modules Development in Operating System Subject with Problem Based Learning Model (Study case: Grade X of TKJ at SMK Negeri 3 Singaraja has proven effective to be applied through some tests. The results of data analysis students' response to the development of e-modules obtained an average score of 68.44 response, if converted into a classification table student responses included in the category of very positive.


New appliance fans with sleeve bearings. Due to technical improvements it has been possible to extend the service life of fans. Special advanced sleeve bearings offering low noise levels with improved resistance against shock and vibration now have led to high reliability which was previously only achieved with ball bearings.


Clinical common gynecologic abdominal pain is easy to be misdiagnosed because of hidden characteristics.Researcher WANG Cheng-rong is the top 10 famous TCM physicians in Sichuan province,whose treatment of this disease has good curative effect.This paper discussed the diagnostic and therapeutic characteristics and promoted the clinical experience of the heritage and development.


The uncertainty of the functioning of higher education institutions in Ukraine in the conditions of Russian aggression, the consequences of the Covid-19 pandemic, actualized the problems of financial stability violations in higher education institutions, which is caused by the following factors: fluctuations in the number of students, their concentration in central universities, outflow from regional universities, changes in their structure , loss of income from foreign students, prioritization of defense expenditures, delay and reduction of budget funding, decrease in the solvency of the population, price competition between higher education institutions, destruction of the material and technical base, migration of applicants and teachers abroad, etc.
The purpose of the article is the methodological substantiation and practical approbation of the assessment of the impact of the change in the contingent on the financial stability of the university, proving the hypothesis that the stability and balance of the contingent has a positive effect on the university's income.
It is substantiated that the change in the contingent of students, their structure by degrees of education, forms of education and sources of funding is one of the indicators of the financial stability of the university. A group of scale indicators is proposed, which includes indicators of the growth of the contingent, in terms of budget and private financing, the average level of university income per student, the average level of university budget allocations per 1st budget student / contract student. The method of calculating scale indicators is defined and their recommended values are proposed to determine the level of their influence on the financial stability of the university.
Based on a sample of thirty-five higher education institutions of Ukraine, which include classical, technical, pedagogical, economic, and other universities, a practical test of the proposed approach was carried out, the obtained results were graphically presented, the main patterns and factors of violation of the financial stability of higher educational institutions were identified.


ABSTRACT Despite being the second Australian jurisdiction to introduce legislative human rights protections in 2006 (Charter of Human Rights and Responsibilities Act 2006 (Vic)), Victoria has failed to bring the legislation governing juvenile detention (the Children, Youth and Families Act 2005 (Vic)) in line with the human rights protections contained in the Charter. This was brought to the fore with the Victorian Government's decision to detain children in a precinct in the Barwon adult maximum security prison in late 2016— a decision that the Supreme Court twice ruled breached the rights of the children protected by the Charter (Certain Children decisions 2016 and 2017). This article focuses on the solitary confinement of children and young people (aged 18 to 24 years) as a specific area in which Victorian legislation fails to comply with the Charter and international human rights law, as well as the main practice that has ultimately led to the first court decision concerning the rights of those in closed environments where the Charter has provided an immediate remedy.


Based on granular computing theory, according to the problem of intrusion detection classification performance reduced by redundant attribute in high dimensional network data, an attribute reduction method of network intrusion detection system based on granular computing is given, the redundant attribute is removed under the condition of keeping the information integrity of original attribute set to reduce the attribute dimension of data. The example analysis indicates that this method reduces the training and detection time, and improves the computing efficiency of system in order to reduce the data storage, it provides a new idea for processing massive large data.


The story of the influence of pressure groups on naive legislators and the trickle down to a non-educational restructure of the Queensland Department of Education.


INTRODUCTION: PEEK (polyetheretherketone) has found use in a broad range of medical applications. Amongst these, PEEK has been demonstrated to be a suitable, low wearing alternative to UHMWPE in spine arthroplasty [1]. Debris derived from implant wear commonly results in a proinflammatory response elicited predominantly by macrophages, with the release of the cytokines TNF-α, IL-1β, IL-6 and other mediators [2, 3]. We hypothesise that as well as PEEK being demonstrated to be of lower wear, the particulate debris generated will be of equal or lower cell reactivity when compared with conventional polymer materials. To test our hypothesis that PEEK elicits a reduced inflammatory response, human THP-1 macrophages were exposed to sterile submicron sized particles of PEEK and UHMWPE, representative of those generated through wear of articulating surfaces in total disk arthroplasty test simulations. The effect of particles on cell function was then assessed by cytotoxicity assay and cytokine analysis.


Understanding the mechanisms of cardiovascular disease progression is essential in developing novel therapies to combat this disease that contributes to 1 in 3 deaths in the United States every year. Endothelial dysfunction and its effects on vessel growth and remodeling are key factors in the progression and localization of atherosclerosis. Much of our understanding in this area has come from in-vivo and in-vitro experiments. However, perfused organ culture systems provide an alternative approach[1]. Organ culture systems can provide a more controlled mechanical, neural, and hormonal environment compared to in-vivo models. This study focused on furthering development of an organ culture model for mouse arteries by introducing a novel device to produce flow waveforms at the high frequencies and low mean flows seen in the mouse model.Copyright © 2010 by ASME


RP5063, a multimodal dopamine (D)–serotonin (5‐HT) stabilizer, possesses high affinity for D2/3/4 and 5‐HT1A/2A/2B/2C/6/7 receptors and moderate affinity for the serotonin transporter. Two phase I studies characterized the pharmacokinetics of a single dose (10 and 15 mg fasting, 15 mg fed/fasting) in healthy volunteers and multiple doses (10, 20, 50, and 100 mg fed) over 10 days in patients with stable schizophrenia. RP5063 displayed a dose‐dependent Cmax at 4 to 6 h, linear dose proportionality for both Cmax and AUC, and a half‐life between 40 and 71 h. In the single‐dose study, food slightly increased the extent of drug absorption. In the multiple‐dose study, steady‐state was approached after 120 h of daily dosing. Pooled data in the single‐dose study indicate that the pharmacokinetic profile appears to be comparable between Japanese and Caucasians. RP5063 appears to have a straightforward pharmacokinetic profile that supports for phase II and III evaluation as a once‐daily oral administered agent.


In this paper, a new strategy of switchable CMOS phase-locked loop frequency synthesizer is proposed, designed and fabricated in 0.5 μm n-well CMOS process. Cadence/Spectre simulation results show that the frequency range of the switchable PLL is between 320 MHz to 1.15 GHz. The experimental results show that the RMS jitter of the PLL changes from 26 ps to 123 ps as output frequency varies. For 700 MHz carrier frequency, the phase noise of PLL reaches as low as -61 dBc/Hz at 10 kHz offset frequency and -104 dBc/Hz at 1 MHz offset frequency. A device degradation model due to hot carrier effects has been used to analyze the jitter and phase noise performance in open loop voltage-controlled oscillator (VCO). The VCO oscillation frequency decreases by approximately 100 to 200 MHz versus the bias voltage and the RMS jitter increases by 40 ps under different PLL output frequencies after 4 hours of stress time.


Quantification and pathological individualization are the two dominant trends within homelessness research. In acquiring near-exclusive status in this research, they constitute a regime of truth and produce a series of unsustainable negations: they deny that they produce the realities which they study, they deny that other realities may be produced, they delegitimise any alternative methodological positionings, and render power relationships and domination invisible, thus obscuring the injustice of life on the streets. As an alternative to this regime of truth, this article argues for the mobilisation of a declared ontological politics that is concerned with the welfare and dignity of homeless people.


Abstract : This paper deals with the calculations of the concentrations of adatoms H (or D) on thr surface of Si which is in thermodynamic equllibrium with hydrogen or deutenium gas.


Innovation has been recognized as an important factor influencing organizational performance. Malaysia as an emerging market has also been pushing for innovation to be the stimulant for growth. Due to huge number of research articles published related to innovation in Malaysia, there is a need to understand the existing state of research related to the topic. This study examines 1824 papers published from 1973 to 2019. Data was extracted from SCOPUS and analyzed using descriptive figures and tables. Additionally this study present the key features of topic modeling based on Latent Dirichlet Allocation (LDA) by extracting coherent research topics that are the focus of the papers analyzed. Through the topic modelling approach this study are able to extract ten coherent research topics from 1824 papers analyzed. This study aim to demonstrate themes related to research on innovation in an emerging market and contributes by summarizing the common keywords used in both the title and abstract of articles published until 2019. Furthermore, this study identified 10 topics based on the abstract of the published articles.


Upscaling is often applied to coarsen highly-detailed geological descriptions. The upscaling of multiphase flow functions is challenging due to their strong dependency on global flow effects. In this work, we present two approaches to generate upscaled two-phase flow functions with global flow effects incorporated. In global two-phase upscaling, the upscaled two-phase functions are directly computed from global fine-scale two-phase solutions. In a new adaptive local-global two-phase upscaling approach, local boundary conditions (for both pressure and saturation) are determined from time-dependent global coarse-scale solutions. This avoids solving global fine-scale two-phase flow. In both approaches, the upscaled two-phase flow functions are adapted to a specific flow scenario, thus providing more accurate coarse models than the use of generic flows. The methods are applied to heterogeneous permeability fields with full-tensor anisotropy. We demonstrate the impact of full-tensor effects on the global flow dependency in two-phase upscaling. It is also shown that the full-tensor effects in two-phase flow are appropriately accounted for by the upscaled two-phase functions with the global flow effects incorporated. The use of those upscaled functions in conjunction with a two-point flux approximation can effectively capture the two-phase crossflow due to the full-tensor anisotropy on the coarse scale.


FIELD: chemistry. SUBSTANCE: concentration of hazardous substances in the working zone of an object, sanitary protection zone, protective action zone and hazardous area of the environment is determined. The obtained results are compared with maximum allowable concentration values. If the obtained results exceed the maximum allowable values, the affected zone and damage effect are predicted, taking into account weather conditions and volume of released hazardous substances. If development of an accident or occurrence of an emergency situation is predicted, mobile analysis laboratories, lidars, permanent control stations for deciding on the emergency situation are set up. The permanent control stations are setup into a triangle and swiftly determine coordinates of possible release of hazardous substances through cross correlation of parametres (detection of affected clouds and blast shockwave) based on the arrival time of signals at the control stations. Certainty of possible release of hazardous substances is confirmed by detection of accident pilot signals by all three stations. On the leeward side relative the centre of the triangle formed by the permanent control stations, an under plume site is also set up, which moves based on data coming from meteorological sensors on the inner (outer) conditional contour of the triangle. EFFECT: increased reliability of control. 2 dwg


The rapid development of artificial intelligence has rapidly changed the pattern of higher education, the structure of talent demand and the mode of future learnings. Artificial intelligence talents should break through the traditional single-subject training mode and form a new model of "artificial intelligence + X" compound professional training in the cross-integration with related subjects. Not only programmers can be called digital talents, such talents who form professional insights and knowledge in specific areas and apply them to the digital field may be needed in the future. Teaching informatization is also of great significance for promoting the reform of the school's talent training model. For example, cross-subject, cross-major learning and informatization can help eliminating the boundaries of the department, and jointly build and share some cross-subjects majors, micro-professionals and MOOC, micro-courses, simulation experiments and other "online virtual classrooms". Artificial intelligence has a strong impact on traditional accounting work, replacing the high repetitiveness in the financial process and the manual operation of occupying a large amount of labor, so that accounting teaching needs to be changed. Promoting the sharing and building of high-quality resources by teaching informatization and providing the soulful university classroom teaching of Chinese wisdom and Chinese programs for the balanced development of education quality to realize the return of learning. Advancing the financial transformation under the intelligent accounting provides a good idea for the accounting teaching. Advocating the implementation of the "learner-centered" educational thinking, paying equal attention to skills and thinking design, and using online courses realize the form of intelligent financial innovation education


Right now around the country, there are growing numbers of libraries embarking upon a refurbishment or building brand new libraries. So it seemed like a good time to talk to the professionals helping us create these wonderful new spaces. INCITE invited Hassell Associate Yan Yan Ho to share her thoughts, fresh from completing the new City Library in Adelaide.


The new organic farmers may differ from their more established colleagues, which may have implications for the development of the organic farming sector and its distinctiveness vis-a-vis conventional production practices. The aim of this study was to explore organic farmers' characteristics, farming goals and conversion motives, grouped by year of conversion (three groups). A survey was undertaken among organic dairy farmers in Norway. The newcomers (converted in 2000 or later) were younger and less educated than the early entrants who converted in 1995 or earlier. The newcomer herds were fed more concentrates and had higher milk production intensity than the herds of the two earlier converting groups. Newcomers more often mentioned goals related to profit and leisure time. The early entrants were more strongly motivated by food quality and soil fertility/pollution issues than the others, whereas financial reasons were relatively more important among the newcomers. Even though trends towards more pragmatic and business oriented farming were found, the majority of the newcomers were fairly committed.


The embodiment of the invention discloses a method for dynamically assigning roaming numbers. The method comprises: obtaining information about the roaming location of the user equipment (UE); sending a number assignment request comprising the roaming location information to a cloud number pool; receiving from the cloud number pool an assigned number corresponding to the roaming location information; sending the assigned number to the UE, wherein the assigned number is used for the UE in the mobile communication network of the roaming location. The embodiment of the invention discloses a number management system. The embodiment of the invention discloses a cloud number pool. The embodiment of the invention discloses a system for dynamically assigning roaming numbers.


Significance Copper is an important biological cofactor, but can also be toxic in excess. Members of the P1B-ATPase family of membrane transporters couple the energy of ATP hydrolysis to translocation of metal ions across membranes. P1B-ATPases have been classified into groups on the basis of sequence and metal ion specificity. Two subfamilies, the P1B-1-ATPases, which are linked to human diseases of copper metabolism, and the P1B-3-ATPases, found only in bacteria, have been assigned as Cu+ and Cu2+ transporters, respectively. Here we show that the P1B-3-ATPases are actually Cu+ transporters, necessitating revision of the classification scheme. These findings are consistent with the presence of only Cu+ in the cytoplasm, which eliminates the need for a Cu2+ efflux pump. The copper-transporting P1B-ATPases, which play a key role in cellular copper homeostasis, have been divided traditionally into two subfamilies, the P1B-1-ATPases or CopAs and the P1B-3-ATPases or CopBs. CopAs selectively export Cu+ whereas previous studies and bioinformatic analyses have suggested that CopBs are specific for Cu2+ export. Biochemical and spectroscopic characterization of Sphaerobacter thermophilus CopB (StCopB) show that, while it does bind Cu2+, the binding site is not the prototypical P1B-ATPase transmembrane site and does not involve sulfur coordination as proposed previously. Most important, StCopB exhibits metal-stimulated ATPase activity in response to Cu+, but not Cu2+, indicating that it is actually a Cu+ transporter. X-ray absorption spectroscopic studies indicate that Cu+ is coordinated by four sulfur ligands, likely derived from conserved cysteine and methionine residues. The histidine-rich N-terminal region of StCopB is required for maximal activity, but is inhibitory in the presence of divalent metal ions. Finally, reconsideration of the P1B-ATPase classification scheme suggests that the P1B-1- and P1B-3-ATPase subfamilies both comprise Cu+ transporters. These results are completely consistent with the known presence of only Cu+ within the reducing environment of the cytoplasm, which should eliminate the need for a Cu2+ P1B-ATPase.


VE161 wheat contains male-sterile substitution line, fertile addition line and fertile heterozygous line with one pair of Elytrigia elongatum chromosomes. The heterozygous line is produced by the substitution line crossed with the addition line. Two maintainable ways of the male-sterility of VE161 alien substitution line are constrasted. The results show that the self-fruitful program of the heterozygous line is better. The effect of the E chromosome on fertility is discussed as well.


This paper describes several art based eco-feedback concepts conceived around the potential of emotional attachment between people and the natural environment. Starting from a sensor-infrastructure that looks at how families consume electricity in their homes, we investigate several artistic visualizations of the Madeiran local landscapes exploring the connection between families and elements of the endemic laurel forest. The approach described here leverages digital art as a means to go beyond traditional eco-feedback technology. By coupling people and the forest landscapes we intend to narrow the physical, temporal and psychological gaps between our everyday actions and nature. We explore how people can build a direct emotional connection between their daily energy consumption and the impact on the natural environment (such as climate change and related forest fires, mudslides, desertification and erosion).


The main goals of this research have been to investigate the basic mechanisms of laser light interaction with biological systems containing intracellular natural absorbers and to find the optimal natural absorber at optimal wavelength and energy for an effective treatment of cancer cells by laser activated cell components. We have developed theoretical models for the temporal and spatial laser heating of intracellular natural absorbers in the surrounding cytoplasm. These models take into account the temperature dependence of the thermo-physical parameters of the absorption centers and surrounding medium, as well as the real-time shape of the laser pulse. Simulations were performed in the diffusion heat-mass transfer mode. It has previously been shown that there are significant morphological changes in some metastasized cancers. We have shown that one of these morphological changes, the enlarged nucleus in metastasized cancerous cells, could potentially be exploited in laser heating to cause ablation-induced necrosis in the cancerous cells while maintaining relatively low necrosis rates in the surrounding healthy tissue even without the use of artificial heat-absorbing nanoparticles.


ABSTRACT As obesity constitutes a growing health concern over the world, it has also become an important part of public policy agendas. This paper critically analyses the development of the policy debate and measures around obesity in the UK. The paper contributes to the debate by challenging the current individualized nature of nudge policies as the most popular application of behavioural economics to policy. We argue that it may be possible to change the choice architecture of individuals through nudge, but the overall effectiveness of such policies would be limited because the broader social, economic and political architecture shaping individual choices is ignored. The case of the UK provides a good illustration where concrete policy measures are predominantly focused on choice despite growing recognition of the structural determinants of obesity, and the governments are thus able to avoid threatening free markets and existing economic interests. Whilst the recently introduced sugar tax constitutes a certain shift in policy, it clearly remains an exception within the whole policy package.


Based on the design of the core modules such as apparatus main body,field control system,high-performance digital combination valve,control software and so on,we develop a multi-function anti-gravity casting system which integrates low-pressure casting,counter-pressure casting and adjustable-pressure casting. The fuzzy self-tuning PID method is used to control the production process in the apparatus operation process. It is convenient to realize the automation control of the integrated pressure casting system by the PC software,and the system has the characteristics of real-time parameter display and graphical display in casting process. The experiments show that the system is of multiple functions,strong practical applicability,can improve the automation degree and the control accuracy,and realizes the process automation of casting system.


Objective To study the efficacy of 3 years alendronate therapy in postmenopausal Chinese women with osteoporosis,and to explore the relationship between early changes in biochemical markers of bone turnover and 3 years response in bone mineral density (BMD).Methods From Aug 2005 to Jan 2006,115 postmenopausal Chinese women with established osteoporosis were enrolled from the outpatient department of osteoporosis,Shanghai First People's Hospital. 70 mg per week alendronate and 800 mg calcium plus 0.25 μg calcitriol supplement were used for up to 3 years. Biochemical markers of bone turnover and BMD in lumbar spine,femoral neck,and total hip were measured. Statistical analysis was carried out using the SPSS 13.0 for Windows.Results 3 years alendronate therapy produced a significant increase in BMD at the lumbar spine (8.1%),femoral neck (3.5%),and total hip (4.0%) (all P0.01). At 6 months,serum alkaline phosphatase (ALP),serum osteocalcin(OC),and urine calcium/creatinine (uCa/Cr) were significantly decreased from baseline (16.7%,24.1%,and 13.4%,respectively,all P0.01). After then,those biochemical markers of bone turnover remained in a low level. Pearson studies revealed that 6 months changes in OC and uCa/Cr were negative correlated with 3 years changes in BMD at the lumbar spine,femoral neck,and total hip (all P0.01). 6 months changes in ALP was also associated with 3 years changes in lumbar spine BMD (r=-0.231 ,P0.01).4 cases of new fracture occurred during treatment.Conclusion Alendronate was effective and safe in post menopausal Chinese women with osteoporosis. 3 years alendronate therapy produced efficacies in increasing in BMD and decreasing in markers of bone turnover,and the early changes in markers of bone turnover were associated with long-term improvement in BMD.


An appropriate choice of practice task w.r.t. their difficulty, and monitoring of progress are central for successful learning of most skills [3]. Motivated by the wish to accelerate and assist a human who is learning a new skill, we propose an extension of MAML for reinforcement learning [1] with a scaffold [3]. We exemplify our approach on the most basic but newly shaped teacher-learner interaction scenario during piano practice. The main idea is to have a model that on one hand guides the human learning process, but on the other hand, adapts to the user and their individual learning needs. By monitoring human performance and its improvement, scaffolded MAML (sMAML) manages task complexity levels, represented by task sets provided for practice. Similar to the MAML concept, for a given complexity level, the meta-learner part of sMAML samples tasks out of the current task set, while the composition of the tasks and their number in the set is monitored by the scaffolding part of sMAML. For each sampled task within the inner loop, the reinforcement learning (RL) model generates concrete score pieces with practice instructions for the learner. During the RL model parameter optimization, the loss is evaluated based of the performance of the human learner. Larger rewards correspond to a more accurate performance of the practice example. Concurrent to the human learning process, the policy update seeks to generate practice examples that maximize reward for a given task level. The scaffolding part of sMAML decides to either stay on the same complexity level, or to change the task set if the performance of the human learner on the test task rapidly improves. The complexity is not raised as long as the human learner is still improving and is not capable to learn a previously unpracticed and slightly more challenging practice piece quickly enough. Analysis of midi produced by the learner and/or capture of movement data may allow us a very detailed error analysis. sMAML is constantly coupled with the human learner through a reciprocal connection, defined by the task set selection and evolution, the quality of human performance and its dynamics. It provides basic implementation of scaffolding functions to the human learner, including performance analysis and monitoring, fading support, gradual task set modification, etc. The main difference to the standard application of MAML is that in our case, the sequences of practice examples corresponding to the action instructions generated by the MAML policy rollouts for a given task Ti ∈ T are executed by the human learner, the reward is generated based on the learner's performance online. If, for example, on the current level, the learner has to play two black keys with two fingers at a given speed and temporal precision, then the sampled tasks may be defined by different speeds, left of right hand, different rhythmic patterns, or different volume instructions. The test task may be to play three black keys with three fingers. To sum up, the meta-learner is responsible for training the learner on one skill level. Once the test phase of the meta-learner shows good adaptation of the human learner to a new task, the scaffold is responsible for changing the task set employed by the meta-learner. This should enable the human learner to move to the next level of complexity. The scaffold has to have an access to a large set of tasks (e.g. [2]), which are bit by bit provided to the meta-learner as the human learner progresses.


Land managers increasingly are becoming dependent upon remote sensing and automated analysis techniques for information gathering and synthesis. Remote sensing and geographic information system (GIS) techniques provide quick and economical information gathering for large areas. The outputs of remote sensing classification and analysis are most effective when combined with a total natural resources data base within the capabilities of a computerized GIS. Some examples are presented of the successes, as well as the problems, in integrating remote sensing and geographic information systems. The need to exploit remotely sensed data and the potential that geographic information systems offer for managing and analyzing such data continues to grow. New microcomputers with vastly enlarged memory, multi-fold increases in operating speed and storage capacity that was previously available only on mainframe computers are a reality. Improved raster GIS software systems have been developed for these high performance microcomputers. Vector GIS systems previously reserved for mini and mainframe systems are available to operate on these enhanced microcomputers. One of the more exciting areas that is beginning to emerge is the integration of both raster and vector formats on a single computer screen. This technology will allow satellite imagery or digital aerial photography to be presented as a background to a vector display.


In order to achieve this paper we have studied the freezing resistance and the effect of low temperatures over the viability of the winter shoots at certain grapevine varieties for the tablegrapes cultivated in the vineyard StefanestiArges. The research concerned the varieties: Argessis, Golden of Stefanesti, Moldova, Augusta, Canner and clones: Muscat Adda 22 St., Perlette 10 St., grafted on Kober 5BB rootstock. The research took place in the period 2010-2012. As a result of the study, we have noticed the sensitivity of Perlette and Augusta varieties at the low temperatures of the winter. We have presented data concerning the determining procedure of the percentage of viable shoots.


In response to the changes in the economic environment at home and abroad, several National Industrial Relocation Demonstration Zones(NIRDZs)have been set up in China's central and western areas since 2010. How does the establishment of NIRDZs affect total factor productivity(TFP)? The answer to this question is of great practical significance to further optimize the development of NIRDZs, change the pattern of economic growth, and promote regional coordinated development.  The TFP of 285 cities at prefecture level is measured by using the Solow Residual method, and the average TFP of these areas shows a downward trend within the observation interval. The three demonstration areas with the highest TFP in 2015 are the Guang'an NIRDZ in Sichuan Province, the Xiangnan NIRDZ in Hunan Province and the Wanjiang NIRDZ in Anhui Province, showing that the quality of economic development in these areas is relatively higher. The three demonstration areas with the lowest TFP are the Yinchuan-Shizuishan NIRDZ in Ningxia Autonomous Region, the Yellow River golden triangle NIRDZ and the Gansu Lanbai NIRDZ, which reflects that these areas have relatively lower input-output efficiency.  A difference-in-differences(DID)approach is used to analyze the policy treatment effect of NIRDZs on regional TFP. The results show that the policy treatment effect on regional TFP in the observation period is negative, indicating that the establishment of NIRDZs for undertaking industrial relocation in central and western areas does not improve regional TFP, more than that, the regional TFP of NIRDZs decreases significantly. There exist obvious regional differences in the policy treatment effect. The effect of the central region is not significant, while that of the western region is significantly negative. The empirical analysis shows that the significant increase of the fixed asset investment after the establishment of NIRDZs is the main cause for the decrease of TFP. The effect of industrial upgrading is not obvious, and the impact of undertaking polluting industry relocation on TFP has regional differences.  Therefore, in order to promote high-quality development in the central and western areas, these regions need to further improve investment efficiency in the process of undertaking industrial relocation, thoroughly implement the concept of green development, and prevent the relocation of backward production capacity and polluting industries. At the same time, they should establish a coordination mechanism for inter-regional industrial relocation and a service mechanism for connecting major projects, promote cluster industrial relocation, strengthen innovation-driven development, and accelerate technological progress, so as to enhance the endogenous growth capacity of these areas.


Possible ways and forms of attaching of children and teenagers to reading on the basis of acquaintance and study at school of modern children and teenage literature are examined in the paper; the leading role of teachers of philology is underlined in the process of forming of reader culture of rising generation. On the example of studying of work of S. Vostokova "Frosya Korovina" working methods with the text on the principle "a polylogue" a teacher – an author – students"


The efficacy test of IB part in the tetravalent inactivated vaccine of ND-IB-EDS76-AE was performed according to the efficacy test method of chicken infection bronchitis inactivated vaccine in the standard for quality of imported veterinary drug.Basic immunization with IB H120 live vaccine and booster immunization with the tetravalent inactivated vaccine were operated in chickens,the sera of chickens were collected on 3~4 weeks after each vaccination,and the IB HI antibody in sera were detected.The result showed that the IB HI antibody titer was 3.6~4.6 log2(1∶12~1∶24) on 3~4 weeks after basic immunization with IB H120 vaccine,and the titer was 6.2~8.6 log2(1∶74~1∶388) after booster immunization with the tetravalent inactivated vaccine,therefore,the IB HI antibody titer after booster immunization was 4.9~26 times higher than before,which was higher than the standard of 3 times.The experiment proved that the proposed method applied to the potency test of IB part in the tetravalent inactivated vaccine was feasible.


Čapek's drama R. U. R., which is rather a social dystopia than a science fi ction (the principle of functioning of robots is not suggested, the drama is focused on the impact on humanity), shows the double face of technology: Th e dream about the "liberation of work" easily takes a turn for its opposite, and for destruction of humanity in consequence of ruthless utilization of the technological achievement for selfi sh economical and militaristic interests. "Autonomous technology", which is not controlled by human aims any more, but by the rules of its own development, became an important subject of philosophy and ethics of technology (e.g. in works by J. Ellul, H. Jonas), and has a warning eff ect. Today, Industry 4.0 and the process of robotization bring new promises, but also new problems. Th e legacy of Karel Čapek includes values of humanism and understanding for other people's views and needs, which is valuable for developing ethics of technology in democratic society.


1510 Background: We update this trial evaluating ZD-1839(Iressa) for treatment of malignant gliomas recurring after radiation therapy and for unresectable benign or anaplastic meningiomas (MEN) progressing after radiation therapy.

METHODS
In the phase II component, patients who were not receiving enzyme inducing anticonvulsants (EIAED) or corticosteroids, were treated with 500mg/ day. The dose in patients receiving corticosteroids was escalated in two increments of 250mg to 1000mg/day. Phase II study was limited to patients with 2 or less relapses. For patients on EIAEDs, a phase 1 component began at 500mg/day and was escalating in 250mg increments. Subjects in the phase 2 component were evaluated for radiological response, time to progression (TTP), and percentage without progression at 6 months (%PFS-26wk).

RESULTS
The MTD for patients on EIAEDs is 1500mg/day. As of 11/19/03, 38 glioblastoma(GBM), 17 anaplastic glioma(AG), and 10 MEN patients had entered phase 2 study. The median TTP for GBM is unchanged at 8 weeks (95%CI:7-12weeks). The median TTP for AG is shortened at 12 weeks (95%CI:7-ND). For both GBM and AG, %PFS-26wk is unchanged at 9%(95%CI:3-27%), and 33%(95%CI: 13-81%). However, 1 GBM patient had SD for 66wks, and 1 is progression free at 93 wks; 4 AG patients had SD for over 50wks. Partial responses (not centrally confirmed) were seen in 5 GBM, 1 AO and 1 anaplastic oligoastrocytoma. No MEN has responed. Skin rash, transaminase elevations, fatigue, diarrhea, and hypokalemia were the most common toxicities. No pulmonary interstitial fibrosis was observed.

CONCLUSION
The MTD for ZD-1839 in patients receiving EIAEDs is 1500mg/day. With complete accrual in both GBM and AG cohorts, ZD-1839 does not prolong TTP compared to historical controls, but subgroups of both GBM and AG demonstrated prolonged TTP. Microdisection based genotyping and determination of EGFR expression is in progress to determine if these tumors are distinguishable from those demonstrating rapid progression. No significant financial relationships to disclose.


The principal thesis of the present book is that the official, so-called 'Uthmanic version of the Qur'an was established by the Prophet Muhammad himself rather than the third Caliph 'Uthman, as is generally affirmed by Muslim tradition and has been accepted by Western scholarship following Noldeke and Schwally. The author holds that this version is the only one that ever existed and that the Muslim reports about variant readings and codices collected by several Companions of Muhammad which were suppressed after the promulgation of the official version by 'Uthman and about the intentional deletion of some verses by Muhammad from the early body of Qur'anic revelations are fictitious. He argues that the primary motive for the invention of these variant versions allegedly sanctioned by the Prophet was the attempt of the Muslim scholars of the law to establish a Qur'anic basis for the legal practice often found to be at variance with the rules laid down in the standard version. In this regard, he analyzes the theory of naskh, abrogation, elaborated by the Muslim scholars, focusing in particular on the variety known as naskh al-tildwa duna l-hukm which implies the deletion of a text from the Qur'an without abrogation of the legal rule established by it. The admission of this type of naskh by some Muslim authorities necessitated, Dr. Burton contends, the exclusion of any role of Muhammad in the collection of the standard version since it would be inconceivable that he himself deleted a passage while maintaining its legal validity. He further suggests that the two verses of the Qur'an referring to the occurrence of naskh or tabdil (II, 106; XVI, 101) mean the abrogation of ritual or legal rules of previous prophetic religions by Islam, not the abrogation or deletion of Qur'anic texts as maintained by Muslim tradition.


This chapter considers the study of post-conflict landscapes in Brazil. Brazil has often been characterized as a violent society for several reasons, not least because of its very visible social inequalities. The chapter presents case study of the Contestado War aim to demonstrate that material culture is a powerful tool and can shed important new light on subaltern stories. The Contestado War occurred in the southern region of Brazil between 1912 and 1916, opposing the local population, known as sertaneja or cabocla, against the state and federal military forces. Archaeology has only recently been added to this burgeoning field. It may seem odd that Brazilian archaeologists have ignored the materialities of this war for so long, but this comes down to the history of archaeology in Brazil. A program of public archaeology offers a means for the valorization of local identities and a way of highlighting the continuing economic and social struggles within the region.


The aim of this bachelor thesis is to clarify what are the possibilities of an educational counselor at the first level of primary schools. The work is focused on overall cooperation in problem solving. This is a pro-run research aimed at clarifying these issues. The conclu-sion is to evaluate the overall process of communication and recommended suggestions for improvement.


By oxidative coupling polymerization a novel electroactive poly(ether sulfone), with fixed conjugated length of oligoaniline (phenyl-capped aniline tetramer) in the main chain, was successfully synthesized. The structure of the electroactive poly(ether sulfone) was confirmed by FTIR, NMR spectroscopy and X-ray powder diffraction (XRD). Electrochemical activity of the poly(ether sulfone) was tested in 1.0 mol·L−1 H2SO4 aqueous solution which shows two redox peaks. Moreover, the thermal properties of the poly(ether sulfone) were investigated by thermogravimetric analysis (TGA). Its electrical conductivity is about 1.37×10−7 S·cm−1 at room temperature upon preliminarily protonic-doped experiment.


As electronic components continue to decrease in size and increase in power, thermal management becomes more important. Devices such as heat sinks and fans can help alleviate thermal problems, but add cost and manufactUling complexity to devices. More intimate knowledge of how a component behaves can allow companies to better determine the viability of a design and reduce over building. In this project, finite element analysis was used to model a microchip from a Lexmark® printer. The results determined by the model were compared to data determined by testing the chip experimentally. The model was used to study the feasibility of using FEA to determine thermal parameters. In a natural convection environment, some thermal parameters of interest include 8 JA , ~JT, and ~JB. The model was then used to perform parametric studies to better understand the effect of physical parameters on thermal properties.


For the purpose of improve the sports level of volleyball,nowadays,the psychological training both during the contest and the training course has been greatly taken into account by volleyball national teams throughout the world.This thesis therefore made an analysis of the psychological phenomenon in the volleyball contest through literature and observation further exploring that how to deal with the disadvantageous psychological state so as to have a progress in the contest by sufficiently exert the skill of the players.


(TKG) we Experimental results show our approach regarding TKG completion and alignment tasks on several TKG datasets due to the effective and efficient integration of time information.


The study presents an acoustic analysis of the phonetic variation in Iu-Mien vowels, not only for modal voice, but also for creaky and pharyngealized vowels. Our findings are contrasted with those of Purnell [1, 2] and Bruhn [3].


The energy crisis facing the world today is the result of the continuous depletion of fossil fuels caused by high usage demand. To alleviate the situation, researchers and scientists have been searching for low-cost, eco-friendly, and readily available substitutes to fossil fuel. Biodiesel can be a promising alternative source of energy. This study investigated the parameters of a direct-injection water-cooled diesel engine run with linseed biodiesel blends. These parameters include brake-specific fuel consumption (BSFC), brake thermal efficiency (BTE), and emission characteristics. Then, the performance of this engine was compared with that of a diesel fuel-run engine by evaluating the BSFC, BTE, and mechanical efficiency. Results show that the BSFC decreases as the load increases for all fuel blends and increases as the percentage of biodiesel in the blend increases; a 25.6% increase in BSFC is obtained at a low load. The BTE increases with increasing load; at a low load, the highest reduction in BTE is 15.38%. The CO emission reduces by approximately 5.49% at a low load for the B30 blend and 27.7% at a high load for the B20 blend compared with diesel. For pollution investigation, the emissions of NOX, HC, and CO were measured. The CO emission reduces by approximately 5.49% while HC and NOX emissions respectively increase by 15.8% and 19.5% at a low load.


The principals, in order to create and maintain humanistic communication with their students, parents of the students and their colleagues, should have a deep perception of the nature of human behaviors, because they always are facing stimulus-response model. Therefore, when there is conflict in stimulus, they should know how to control the responses and behaviors, and any kind of carelessness in responding can intensify negative emotional resistance and will hold back the organization. The principals, in order to be aware from different aspects of conflict within the school organization, and deliberately choose conflict management styles, so that tend to repeat them and do not realize them as undesirable or harmful behaviors, should identify conflict process and the factors causing conflict and deal with them in one way or another. Present work aims to inform individuals and education authorities about the importance of conflict management and different styles of conflict management that principals can adopt in case of conflict...


Objectives : Generally, it seemed that the therapeutic result in diabetic patients was changed by compliance. This study was conducted on the basis of assumption that the therapeutic result id diabetic patients could control according to compliance. This study was conducted to analyze the related factors in association with compliance to drug, diet and exercise therapy. Methods : 224 diabetic patients in Kyungpook National University Hospital were selected through the interviews and HbA1c values from 1 Jan. to 28 Feb.1997. The drug compliance was tested by regularity of drug administration, the diet compliance was tested by restriction of food, exactly allocation, balance of nutrient, measuring food and the exercise compliance was tested by regularity of exercise per day. We assessed compliance by percentage, and generalized logit regression model(method:enter). Results : The significant variable was the satisfaction to medical personnels in drug, the knowledge to disease in diet, the participation of the diabetic education in exercise therapy and the satisfaction to medical personnels in HbA1c. Using the generalized logit model(method : enter) in compliance change, the significant variables were the satisfaction to medical personnels and the complication in drug; the significant variables were the age at the first diagnosis, the family history, the concern of health, the knowledge of disease, the self-exertion for therapy and the complication in diet: the only significant variable was the gender in exercise therapy. Conclusions : The degree of glycemic control in diabetic patients was influenced by compliance. In order to improve patient's compliance, we must foster the knowledge on the diseases, lead participation for diabetic education. Because the satisfaction to medical personnels was the important variables, we must build up good relationship between doctors and patients.


then the flow will be reversed. This inequality can clearly be satisfied if T is small. The length of time for which the flow is arrested will depend on the magnitude of the impulse coefficient A0 . Alternatively, if another impulse follows the first rapidly enough, the flow will remain arrested for a further period. In the case of the circular pipe the basic flow causes a discharge iraum . So the total flux due to a single pulse and the basic flow is


The invention relates to hydrophobic compositions that increase the viscosity of aqueous media containing water-soluble electrolytes, and allows the increase in the viscosity of the composition in the presence of an electrolyte. The composition comprises a water soluble copolymer 99.9 - 99.975 mol. % Acrylamide and 0.025 -. 0.1 mol% dodetsilpoli (oxyethylene) Nmetakrilata with a viscosity of 0.2% solution of the copolymer at 25 ° C Brookfield 6,8 - 1075sP or copolymer 74.8 -. 74.95 mol% acrylamide, 0.05 -. 0.2 mol% dodetsilpoli (oxyethylene) Nmetakrilata and 25 mol% of acrylic acid with a viscosity of 0.2-foot copolymer solution at 25 ° C on a Brookfield 1000 -. 1300sP in which N-number of oxyethylene . units 10 or 20, with the following component ratio, wt%: water-soluble copolymer 0.2 - 0.5 Sodium chloride 1 - 4 water - the rest. Table 4.


Distribution systems operators are often confronted with declined power quality, which can cause substantial economical losses. The problem analyzed in paper concerns thyristor controlled direct current motor used for ski-lift in ski resort as a source of disturbances with negative impact on sensitive electric equipment, which is then unable to operate correctly. To solve mentioned problems, series of measurements of voltage quality parameters were carried out according to the respective valid standards. Crucial power quality parameters necessary for parallel power active filter design were then analyzed. Power active filter compensates power factor and filters characteristic current harmonics. After power active filter was put into operation, power quality problems were eliminated. Payback period is estimated up to four years.


In this paper the hydrodynamics and shell side mass transfer of laminar flow across in-line tube arrays is studied numerically. The hydrodynamics of a five-tube array were described by the two-dimensional Navier-Stokes equations, employing the stream function-vorticity method. After a converged solution of the hydrodynamics had been found, a transport equation for the concentration was solved. The numerical grid of the investigated geometries consists of a number of basic cells, which are generated with a domain decomposition method combined with orthogonal grid generation. The hydrodynamics and mass transfer were analysed for Reynolds = 2-200, Peclet = 10-300 and pitch-to-diameter ratios of 1.5, 1.85 and 2.0. It is shown that the strength of the recirculation occuring between the adjacent tubes increases with increasing Reynolds number, and with decreasing pitch-to-diameter ratio.


Introduction: The concept of hospital resilience means "the ability of a hospital to withstand, absorb and respond to catastrophic shocks ."Humans have been plagued by a variety of disasters throughout their lives, including emerging diseases, and have suffered irreparable loss. Hospitals play a key role in crisis management and control of epidemics, and therefore the hospitals readiness to continue medical services in crises is of particular importance. Therefore, the present study was conducted with the aim of obtaining effective indicators on hospital resilience in epidemic conditions.
Materials and Methods: A qualitative study was conducted to identify the indicators. The main method of data collection was semi-structured interviews with experts and also review of extensive texts. Finally, using qualitative content analysis method and with the help of MAXQDA software, the main dimensions, indicators and below Indicators were extracted.
Results: According to the results, the main dimensions included: 3 dimensions (management and leadership, readiness and adaptability capacity ) and the main indicators include 11 indicators (manpower management, support services management, disease management, cohesion and structuring, redundancy, knowledge management, Organizational culture, service delivery, infection prevention and control, environmental health, recovery). The number of sub-main indicators is also 43.
Conclusion: In order to improve resilience, hospitals can focus on the identified indicators and monitor and improve them. Correction and improvement of effective indicators will lead to the promotion of resilience and effective management and control of pandemic crises in hospitals.


ABSTRACT Humanistic psychology is grounded in dialogic communication and existentialist phenomenology, involving a relational philosophy and experientialist methodology. Its relative neglect within listening research is canvased before exploring the praxis of Gestalt therapy – a humanistic psychotherapy – which models integration of philosophy, theory, and practice relevant to listening. While listening research is increasingly attuned to relational aspects of communication and elements of humanistic therapies, it remains shaped by a metaphysics of atomization, compromising its capacity for integrated praxis. The value of conceptualizing listening as a praxis similar to that of Gestalt therapy is therefore elucidated, with particular reference to listening pedagogy in higher education.


This study aims to investigate the perception of undergraduate students about their lecturers' behaviours in their learning environment. Behaviour is the explanation of observable outcomes and interaction between students and instructors. Behaviour can be positive, negative, effective or ineffective, and the way in which lecturers behave with their students in the learning environment may affect their learning experience and motivation. A Quantitative research design was employed in conducting the study. A questionnaire with 27 items was used to collect data from 140 randomly selected respondents from Takhar University, Afghanistan. SPSS version 25.0 was used to analyze the data. Descriptive statistics and inferential statistics, i.e., Independent Samples t-test and One-Way ANOVA were employed in data analysis. The findings indicate that the students had a positive perception about their lecturers' behaviours in the learning environment. The study also revealed that there did not appear to be any statistically significant differences in participants' responses by their gender or the classes they took. The findings of the current study may lead to policies with regard to lecturers' behaviours and inform instructors to improve classroom practices in the learning environment.


To study the density-tolerance of semi-erect panicle type in rice,14 Japonica varieties,belonging to 3 spike types,were grown in the two densities level( 30 cm,25 cm). The results show that,in low density,leaf area index( LAI) of the semi-erect panicle type varieties was significantly lower than that in the curved panicle type varieties,efficient leaf area of semi-erect panicle type variety was significantly greater than that of the upright rod spike type and curved panicle type varieties. During increasing the density,LAI in semierect panicle type varieties show little changed,but the high efficient leaf area was increased significantly. In high density,plant height and ear length in semi-erect panicle type varieties were significantly reduced compared with the curved panicle type varieties. Grain density in semi-erect panicle type varieties was significantly lower than that in the upright rod spike type cultivars. In semi-erect panicle type,flag leaf and top 2 leaf length was significantly longer than that in the upright rod spike type cultivars,leaf width was significantly wider than that in the curved panicle type varieties. With increasing the density,individuals of semi-erect panicle type tend to convergence. In high density,semi-erect panicle type show higher lodging resistance than the curved panicle type varieties,higher seed setting rate than the upright rod spike type cultivars,and higher milled rice rate and yield. Taken together,semi-erect panicle type is more density tolerant than two other spike types,which attributed to,suitable ear rise and plant height( 85 cm ~ 90 cm),increasing individuals convergence and effective leaf area,more panicle number per square meters and lodging resistance. Thus,the total yield of semi-erect panicle type is significantly increased in high density,which is the key and base for high density growth cultivation.


The author examines four areas in teaching men's studies courses: the need to develop a male perspective and male voice amid a preponderance of female students in the courses, the need to move from men-as-historical-objects toward more subjective experiences of men, the need to address the political aspects of men's studies, and, last, the need for a historical and cultural context. The four issues are incorporated into a hands-on accounting of the author's experiences in teaching the courses with emphasis on consciousness raising, changing perspective, confronting stereotypes and sexism, students' emotional reactions to the topics, and development of analytical thinking. Examples are given in dealing with some of these issues.


We report the observation of single nanotube fragmentation, under tensile stresses, using nanotube-containing thin polymeric films. Similar fragmentation tests with single fibers instead of nanotubes are routinely performed to study the fiber-matrix stress transfer ability in fiber composite materials, and thus the efficiency and quality of composite interfaces. The multiwall nanotube-matrix stress transfer efficiency is estimated to be at least one order of magnitude larger than in conventional fiber-based composites.


effort, whether in Yemen or elsewhere, has real social and political effects and these are often similar in a variety of different settings around the globe. What is most valuable in the study under review is the emphasis on Salafis deriving their ideas and authority from multiple levels: the local, the global, and the transnational. This work, however, could have benefited from better editing and the correction of the multiple errors in transliteration. Finally, Bonnefoy overstresses the local and transnational agency of individuals while diminishing the role that state governments play in the politics of religion. As he acknowledges but does not sufficiently emphasize, the republican government in Yemen has been promoting a version of Salafism that has a local genealogy dating back to the 15th century. It has used an array of tools in order to accomplish this (e.g., channeling Saudi funding, legal reform, control of mosques, setting school and university curriculums, etc.) and all with the aim of generating a form of "Yemeni Islam" that would break with Zaydi Shi ism. The government claims to rise above the sectarian and legal pluralism that defined the country's past. This is in fact false because the Yemeni state has promoted its own version of what one might term "Republican Salafism." Without sufficiently taking account of this state project to define Islam in Yemen, it is impossible to understand, let alone account for, the rise and success of the Salafis described by Bonnefoy. States continue to matter, for better or worse.


This paper describes a novel idea of image analysis method of pulse laser in-line hologram of particles to obtain information on particle diameter. Present method is based on the following property of the hologram. Fringe interval of the hologram decreases with radius, and the corresponding spatial frequency increases with radius. Fourier transformed pattern of the hologram, therefore, has the similar properties. We have proposed here the use of this FFT pattern of the hologram for the image analysis. It is shown that the FFT pattern has a white ring zone, which corresponds to the zero-point of the envelope function of original fringe pattern. It is demonstrated that measurement of the diameter of this ring gives a reliable way of obtaining particle diameter. Feasibility of the method has been shown by numerical experiment for Fraunhofer and Fresnel hologram.


We present a tectonic model for the generation of quartzofeldspathic veins and pegmatite dikes found in southern New England that proposes the following: (1) Hydraulic fracturing produces the initial fracture that opens to become a vein, and (2) oscillating differential stress produces a gradient in interstitial fluid pressure that draws the melt to the dilating walls of the fracture. Oscillating fluid pressures at the dike walls lead to oscillating rates of crystallization, and thus to alternating aplitic and pegmatitic textures in dikes as thin as a few centimeters. Excess alkalis and SiO2(aq) lower the solidus temperature of the granitic liquid and thus stabilize a peralkaline silicate liquid without crystallization. This silicate liquid is capable of crystallizing only quartz, only feldspars, or both. Crystallization of this liquid lowers its pH and accounts for the mineralogical zoning consisting of quartz cores, feldspathic mantles, and muscovite-bearing margins common in many quartzofeldspathic veins.


This article examines Monsignor John A. Ryan's advocacy on behalf of social reform between 1892 and 1945. It is argued that Ryan took the roles of priest, prophet, and politician, and that each of these roles called forth its own distinctive form of argumentation on behalf of social change. By examining each of these roles and Ryan's use of argument from authority, causality, and circumstance, both the form and dimensions of Ryan's rhetorical career are revealed. Social role, rather than political philosophy, is shown to be the motivator of argumentative technique.


The invention relates to a device (100) for non-destructive testing of a wheel set shaft, comprising a supporting frame (101) with at least one probe and a plurality of guide rollers (102), wherein the support frame (101) along a first longitudinal axis has a substantially arcuate contour, and by means of guide rollers (102) against the surface of the axle and supported on this movable in the circumferential direction thereof. The invention aims to improve the reliability and practicality of the device even under the spatially very restricted conditions within the installation space of wheel sets in rail vehicles. For this purpose, it is provided that the apparatus further comprises a tilt sensor (106).


This paper presents a novel approach to generate bag-of-words model based trajectory descriptions for handwritten strokes. We demonstrate how multiple distinct representations can be generated for the same stroke to accommodate writing variations and capture local features at stroke-segment level. The proposed descriptions can be utilized in template matching for handwriting recognition/correction, writer identification, signature verification, etc. The suitability of the proposed shape representations is experimented in a number of settings and used to build a language independent pen-based system for handwriting learning with feedback.


A method to isolate specific regions of the Drosophila polytene chromosome using an atomic force microscope (AFM) was explored. The AFM was used for the microdissection of the locus of interest with much greater precision than standard microdissection techniques. The amplification of DNA isolated in this fashion by the polymerase chain reaction (PCR) is discussed. A study of the effect of hydration level on gross chromosome structure was carried out. It was shown that chromosome swelling is dependent upon humidity or the buffered medium. The significance of this swelling with respect to studies of chromosome structure under physiological conditions is considered.


Metallic antimony (Sb) with gray allotrope has rarely been considered from the viewpoint of two‐dimension layered system is actually a graphite‐like material, in which Sb layers consist of fused, ruffled, and six‐membered rings. Given that metallic Sb nanosheets can be played like graphene, it would be anticipated to obtain a new anode material with superior electrochemical performances for sodium storage. In this work, we propose an efficient strategy to fabricate free‐standing metallic Sb nanosheets via liquid‐phase exfoliation of gray Sb powder in an ios‐propyle alcohol (IPA) solution with a constant concentration of sodium hydroxide. As a proof of the concept, several hybrid films composed of metallic Sb nanosheets and graphene with tunable densities are achieved, in which the notorious volume change of metallic Sb can be efficiently alleviated with the aid of the good flexible graphene, and the whole density of electrode films can be significantly improved by harnessing the high density of Sb nanosheets. As a consequence, the optimized metallic Sb nanosheets‐graphene (SbNS‐G) film displays a high volumetric capacity of 1226 mAh cm–3, high‐rate capability and good cycle performance for sodium storage.


Eccentric and concentric unconfined compression tests are conducted to examine the influence of strain gradients on the brittle failure of ice. Fresh-water columnar-grained ice specimens are tested at a temperature of -10°C and average strain rates of approximately 10\u–\u4 s\u–¹. Considering the strain varies linearly across a specimen, the stress distribution is determined from conditions of equilibrium of forces and moments. At failure, the average stresses for eccentrically loaded specimens are usually less than those for concentrically loaded ones. In the case of eccentrically loaded specimens, however, local stresses at some point along the specimen's width (usually one of the sides) reach a maximum value exceeding the average stress for a concentrically loaded specimen. Measured failure stresses show some scatter, which is commonly observed for brittle failure. Nonetheless, the maximum local stress reached in a specimen appears to increase with increasing strain (or stress) gradient. The maximum stress-strain gradient dependence provides an explanation of the apparent size effect on ice failure stresses.


Driven by increasing precision and accuracy requirements due to miniaturization and performance enhancement, measuring technologies need alternative ways of positioning, probing and measurement strategies. The paper describes the operation of the high-precision wide scale three-dimensional nanopositioning and nanomeasuring machine (NPM-Machine) having a resolution of 0.1 nm over the positioning and measuring range of 25 mm x 25 mm x 5 mm. The NPM-Machine has been developed by the Technische Universitat Ilmenau and manufactured by the SIOS Messtechnik GmbH Ilmenau. Three plane-mirror miniature interferometers and two angular sensors are arranged, to realize in all three coordinates zero Abbe offset measurements. Therefore, this device closes a gap in coordinate-measuring technique regarding resolution, accuracy and measuring range. The machines are operating successfully in several German and foreign research institutes including the Physikalisch-Technische Bundesanstalt (PTB). The integration of several, optical and tactile probe systems and scanning force microscopes makes the NPM-Machine suitable for various tasks, such as large-area scanning probe microscopy, mask and water inspection, circuit testing as well as measuring optical and mechanical precision work pieces such as micro lens arrays, concave lenses, step height standards.


Ability to stand up to adversities, having the flexibility to solve problems in the most meaningful way and coming to a better situation compared to the starting point is regarded as resilience by organization researchers. Conditions that shapes organizational capacities in a flexible, storable and convertible way give rise to resilience in organizations and make them powerful in coping with problems, turmoils and crises. Without doubt, resilient individiuals effect overall resilience of groups, especially in group level a resilient leadership is a prerequisite of resilient organizations. By resilient organizations we mean flexible and adaptive organizations that can positively cope with the unexpected or unwanted. Therefore, in this study positive psychology and positive organizational behavior literature are regarded as good guides for presenting a suitable leadership style for adaptive and resilient organizations. In this study, specifically, authentic leadership style, most prominent leadership type was under spotlight as one of the main sources of organizational resilience.


ion is not just a feature of our thinking but the most basic feature of reality itself whose organic unity is always and by defi nition ruined.


Let \K denote an algebraically closed field and let V denote a vector space over \K with finite positive dimension. We consider an ordered pair of linear transformations A:V\to V,A*:V \to V that satisfy the following conditions:(i)Each of A,A* is diagonalizable;(ii)there exists an ordering {V_i}_{i=0}^d of the eigenspaces of A such that A*V_i\subseteq V_{i-1}+V_i+V_{i+1} for 0\leq i\leq d, where V_{-1}=0 and V_{d+1}=0;(iii)there exists an ordering {V*_i}_{i=0}^\delta of the eigenspaces of A* such that A V*_i\subseteq V*_{i-1}+V*_i+V*_{i+1} for 0\leq i\leq\delta, where V*_{-1}=0 and V*_{\delta+1}=0;(iv)there does not exist a subspace W of V such that AW\subseteq W,A*W\subseteq W,W\neq 0,W\neq V. We call such a pair a tridiagonal pair on V. It is known that d=\delta; to avoid trivialities assume d\geq 1. We assume that A,A* belongs to a family of tridiagonal pairs said to have q-Racah type. This is the most general type of tridiagonal pair. Let {U_i}_{i=0}^d and {U_i^\Downarrow}_{i=0}^d denote the first and second split decompositions of V. In an earlier paper we introduced the double lowering operator \psi:V\to V. One feature of \psi is that both \psi U_i\subseteq U_{i-1} and \psi U_i^\Downarrow\subseteq U_{i-1}^\Downarrow for 0\leq i\leq d. Define linear transformations K:V\to V and B:V\to V such that (K-q^{d-2i}I)U_i=0 and (B-q^{d-2i}I)U_i^\Downarrow=0 for 0\leq i\leq d. Our results are summarized as follows. Using \psi,K,B we obtain two actions of Uq(sl2) on V. For each of these Uq(sl2)-module structures, the Chevalley generator e acts as a scalar multiple of \psi. For each of the Uq(sl2)-module structures, we compute the action of the Casimir element on V. We show that these two actions agree. Using this fact, we express \psi as a rational function of K^{\pm 1},B^{\pm 1} in several ways. Eliminating \psi from these equations we find that K,B are related by a quadratic equation.


This article mainly discusses gold r esources appraisement of south Ningxia based on ArcView platform.In appraisal process,spatial data a re edited,managed and analyzed in th e platform,a gold ore resource location appraisal model is built through Ave nue,which is a secondary developmen t language of ArcView,and a gold ore resource quantity appraisal model i s built through Visual C program,at t he same time,the resource quantity appraisal model has a little impact coupling with ArcView.The models ful fill an ore deposit location assessm ent and gold ore resources assessment succe ssfully,and bring forward an assessment outcome and work suggestions fo r production departments.Furthermo re,it offers us a new method and thought for GIS applying in ore resources assessment of West China.


On the nature the dominant composition of water-stone debris flow is coarse particles,but there are a few fine particles as suspended load in the flow.In such case, the transport concentration of solid depends not only on the slope of gully,but also on the content of fine particles.It is found that due to the existence of fine particles in flow,the transport concentration of solid will increase with the same slope of gully.In this paper, a velocity formula of water stone debris flow with and without fine particles is developed and verified by field data.Studies also indicated that in case of low concentration(S v0.45)the influence of fine particles on the velocity of flow is little,but in case of high concentration(S v0.45) the velocity of flow significantly increase as the content of fine particles increase.


Current-pumped picosecond-range laser diodes with a peak power significantly exceeding that achievable from gainswitched lasers are of major interest for a large variety of commercial applications. A group of phenomena have been explored in which the peak transient gain is efficiently controlled by a fast reduction in the pumping current. Common to all these phenomena is the fact that the peak powers of the emitted picosecond optical pulses (15-100 ps) exceed that obtainable from gain-switched laser diodes by at least an order of magnitude, although the physical reasons for the high gain and the design principles of the semiconductor structures are different. The main problem in the realization of these picosecond modes in low-cost practical systems is the high sensitivity of the operation regime to structural and circuit parameters. A related problem is the questionable reproducibility of the fabrication processes used so far. Proper development of reliable high-power picosecond transmitters will require the use of more advanced fabrication methods and further study of the effect of structural parameters on the properties of the picosecond lasing mode. In this paper we report on a record value for the power density of the picosecond lasing (50W / 30ps) obtained from a laser diode chip of width 20 &mgr;m and give a qualitative interpretation of the operating mode. Use of the MOCVD process for diode fabrication should allow reproducible technology for picosecond laser diodes to be developed.


In numerical analysis, formulation of curved structural elements is a challenge due to the so-called locking phenomena. Locking occurs as spurious strain caused by inability of an element to properly evaluate membrane, shear and bending stiffness. The structure becomes too stiff making displacements significantly smaller than in real structure. A wide range of methods have been proposed to overcome this locking phenomena. Some among them are: reduced/selective integration, strain method, anisoparametric interpolations, hybrid or mixed formulations etc. In this paper, mixed formulation (hybrid displacement/strain formulation) based on Isogometric analysis (IGA) is presented. The basic idea of IGA is to directly use functions which describe geometry (in this case Non- uniform rational BSpline, or NURBS) as the interpolation functions for the unknown fields of interest (displacement and strain). This paper primary focuses on the isogeometric approach for static and dynamic analysis of thin curved beams by using mixed formulation. Results are compared with analytical solutions and with conventional displacement based formulation. MATLAB code is developed for isogeometric analysis of both mixed and displacement based formulation.


Critical ability is one of the main abilities needed in the industrial revolution 4.0 and society 5.0. Based on these explanations, this study aims to develop assessment as learning in drama appreciation learning and test the effectiveness of these assessments in improving students' appreciative critical abilities. The product developed is a teacher's handbook in implementing assessment as learning in drama appreciation learning. There are three parts in this product developed and validated by experts which contain activities to improve students' appreciative critical abilities. The first part is the display aspect of the book which gets a score of 70%. For the second part, the content aspect of the book gets a score of 73.3%, and the third, the language aspect gets a score of 70%.There are two aspects that are rated by students, namely the impression and message aspects regarding assessment as learning in increasing students 'appreciative critical abilities and the practicality of assessment as learning in increasing students' appreciative critical abilities. For the first aspect, it gets score of 80.4% and the second aspect gets an average score of 82%. Overall, the score obtained explains that assessment as learning can be implemented in drama appreciation learning to improve students' appreciative critical abilities.


This paper presents an analytical study of a new stand-alone agriculture greenhouse (GH) system. This system utilizes the excess solar radiation (more than that required by the plants for photosynthetic process) to generate electricity via a set of Photo Voltaic/Thermal (PV/T) units which are placed on the GH roof and south side. In addition to electricity generation, PV/Ts reduce the cooling load of the GH and help the system to be naturally ventilated. The system recovers the GH air humidity, including the plants transpiration, and uses it as irrigating water. Two coupled mathematical models are developed using MATLAB. The first model calculates the absorbed and transmitted solar radiation by/through each GH surface for a Clear Sky Day. The results of the first model are used as inputs to the second one that predicts the GH performance (GH surfaces and air temperatures, air relative humidity, air velocity, water production, electricity production and power consumption). These models are applied on climate conditions of Zagazig city, Sharqia, Egypt. The results show that the system presents a good solution for water shortage in Egypt as it has the ability to provide suitable climate conditions for plant growth (high quality and quantity) and produce enough water for irrigation purposes.


In the recent years, the high speed of economic development and great strength of exploitation of natural resources have given rise to a series of resource environmental problems. This paper analyzes the main reason of such problems, and puts forward some countermeasures as follows: optimizing industrial structure and distribution pushing green industry and cleaning production, increasing environmental investment and reinforcing the construct of basic environmental establishment, synthesizing decisions and policies for perfect city environmental planning, improving ecological observation stations, establishing city environmental information disposal system and beforehand alarming system, for the ecosystem supervision of the city, reinforcing law construction, completing rules of law, and strictly executing the law .


Tourism has an important role in regional development particularly in the improvement of quality of life and human life. Many tourism activities have been developed in hazard areas and consequently it has risks to the disaster. Disaster in tourism areas influences the performance of tourism particularly the number of tourist who visit the areas. The impact of disaster depends on disaster characteristics, vulnerability, and capacity of tourism areas. The impact will be experienced not only by tourist and tourism employees but also by other sectors and population in the area, as well as other related areas. Based on the important role of tourism in site/regional development and the impact which might be causedbu the disaster, management of disaster particularly disaster mitigation is important in the development of tourism areas. Keywords : dampak kebencanaan, kawasan wisata, mitigasi


A physician discusses the benefits of a Saturday clinic that is operated by Colorado medical students to serve working and unemployed homeless patients. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.


In a previous paper, the potential advantages of synchronous averaging in the measurement of distortion produce otoacoustic emissions were presented. In this work, the authors compare measurements using both methods. The superior signal to noise ratio and improved sensitivity of synchronous averaging is observed in the experiments.


Introduction Rhetoric and Conflict in Apartheid South Africa South Africa's Rhetoric of Violent Conflict Rhetorical Change Rhetoric and Negotiations for a New South Africa Talking About Talks Negotiations, Civil Wars, and a Revolution by Force... Almost A Glorious Human Achievement South Africa and the Prospect for Civic Discourse in the Third Millennium References


Academics in the disci-lines of marketing, organizational psychology, and management have recently called for more research on the impact of total quality management (TQM) in their fields. According to Japanese industrial standards, TQM is a system of m..


In smooth muscle cells, development of force results from MgA TP-dependent cyclic interactions of myosin in thick filaments with actin in thin filaments. The force of contraction, in turn, is regulated by the concentration of free Ca2+ surrounding these myofilaments. The purposes of the present chapter are to discuss (a) Ca2+ -dependent mechanisms other than myosin light chain phosphorylation by which contractile force in smooth muscle may be reg ulated, and (b) other second messenger mechanisms that regulate contractile elements or the myosin kinase/phosphatase system . Since the discovery that phosphorylation of the 20-kDa light chains of myosin by Ca2+ /calmodulin-dependent myosin light chain kinase allows smooth muscle myosin MgATPase to be activated by actin, many in vestigators have studied the relationship between light chain phosphorylation and active force in smooth muscle (reviewed in 42; Hai & Murphy, this volume). It is generally accepted that myosin phosphorylation and de phosphorylation are sufficient to regulate contraction. While myosin phos phorylatiOn/dephosphorylation may be the dominant regulatory pathway, the coexistence of thin-filament linked regulation is not ruled out (51).


This project is aimed at analyzing the amount of electrical and electronic products that were previously and are currently in circulation in Australia and how this is recycled and disposed of when they reach their end of useful
live. It was not possible to find the exact figures of these volumes since the data found from the Australian Bureau of Statistics contained only some of the consumer electrical and electronic equipment imported into the country
in 2004 and that data was used to make possible assumptions regarding the numbers in circulation and being disposed of this equipment in Australia. It was also observed that there were no active proper recycling activities in place specifically for the electrical and electronic equipment in Australia. And this has eventually led to a lot of Waste Electrical and Electronic Equipment (WEEE) being disposed of into the landfills. The negative and positive impacts of these disposals on the environment were also analyzed.
The small recycling activities and disposals of WEEE have also been found to have been performed without measures ensuring that these are done in a manner not endangering the public health and the environment.


Background: In infants and children with fractures from an unclear cause, osteogenesis imperfecta (OI) is often included as a potential etiology. In infants and children with OI there exists a gap in the published literature regarding the fracture pattern seen at the time of diagnosis. As an additional aid to the diagnosis of OI, we sought to characterize the fracture patterns in infants and children at the time of their diagnosis. Methods: We performed a retrospective chart review of a series of infants and children under 18 years of age who have the diagnosis of OI (any type) from a single institution. Results: We identified 68 infants and children with OI: 23 (34%) type 1, 1 (2%) type 2, 17 (25%) type 3, 24 (35%) type 4, and 3 (4%) unknown type. A family history of OI was present in 46% of children. Forty-nine (72.0%) patients were diagnosed solely on clinical characteristics, without genetic or fibroblast confirmation. Rib fractures were noted in 21% of the subjects with none being identified during infancy. The number of fractures identified at diagnosis ranged from 1 to >37 with 7 (10%) having more than 2 fractures. All subjects with more than 2 fractures were diagnosed prenatally or in the immediate newborn period. Seventeen (25%) infants were diagnosed after 1 week of age but before 12 months of age. None of these infants had either rib fractures or more than 1 fracture at the time of diagnosis. Conclusions: The majority of children diagnosed with OI are diagnosed by clinical features alone. The fracture pattern at the time of diagnosis in OI is variable with 10% having more than 2 fractures. The diagnosis of OI was made in utero or at delivery in 43% of children. Multiple rib fractures in an infant would be an unexpected finding in OI. Level of Evidence: Level III.


This is an example of reading a biblical text as a narrative unity. The article argues for the holistic reading of the whole of 1 Sam 25. What some scholars argue for an appended v. 1 and vv. 43-44, will be seen as integral part of the whole narrative of trying to preserve the characterization of David as a divinely-appointed king, an act that is given a suspenseful start in the loss of David's protector in the person of Samuel (v. 1), and provided with a theological support in David's marriage to Abigail, a marriage that is set as an ideal one compared to David other marriages mentioned in the narrative (vv. 43-44).


One of the current research areas in the synthetic aperture radar (SAR) processing fields is deep learning-based ship detection in SAR imagery. Recently, ship detection in SAR images has achieved continuous breakthroughs in detection precision. However, determining how to strike a better balance between the precision and complexity of the algorithm is very meaningful for real-time object detection in real SAR application scenarios, and has attracted extensive attention from scholars. In this paper, a lightweight object detection framework for radar ship detection named multiple hybrid attentions ship detector (MHASD) with multiple hybrid attention mechanisms is proposed. It aims to reduce the complexity without loss of detection precision. First, considering that the ship features in SAR images are not inconspicuous compared with other images, a hybrid attention residual module (HARM) is developed in the deep-level layer to obtain features rapidly and effectively via the local channel attention and the parallel self-attentions. Meanwhile, it is also capable of ensuring high detection precision of the model. Second, an attention-based feature fusion scheme (AFFS) is proposed in the model neck to further heighten the features of the object. Meanwhile, AFFS constructs and develops a fresh hybrid attention feature fusion module (HAFFM) upon the local channel and spatial attentions to guarantee the applicability of the detection model. The Large-Scale SAR Ship Detection Dataset-v1.0 (LS-SSDD-v1.0) experimental results demonstrate that MHASD can balance detection speed and precision (improving average precision by 1.2% and achieving 13.7 GFLOPS). More importantly, extensive experiments on the SAR Ship Detection Dataset (SSDD) demonstrate that the proposed method is less affected by the background such as ports and rocks.


We study ultrafast magnetization quenching of ferromagnetic iron following excitation by an optical vs a terahertz pump pulse. While the optical pump (photon energy of 3.1 eV) induces a strongly nonthermal electron distribution, terahertz excitation (~4 meV) results in a quasi-thermal perturbation of the electron population. The pump-induced spin and electron dynamics are interrogated by the magneto-optic Kerr effect (MOKE). A deconvolution procedure allows us to push the time resolution down to 130 fs, even though the driving terahertz pulse is more than 0.5 ps long. Remarkably, the MOKE signals exhibit an almost identical time evolution for both optical and terahertz pump pulses, despite the three orders of magnitude different number of excited electrons. We are able to quantitatively explain our results using a model based on quasi-elastic spin-flip scattering. It shows that in the small-perturbation limit, the rate of demagnetization of a metallic ferromagnet is proportional to the excess energy of the electrons, independent of the precise shape of their distribution. Our results reveal that the dynamics of ultrafast demagnetization and of the closely related terahertz spin transport do not depend on the pump photon energy.


In today's world both individuals and the organisations have tough time in bringing work-life balance. In organizational perspective, a high standard of work–life balance is essential to continue attracting and retaining its employees; while at the individuals perspective it has a positive impact on attitude, behaviour, and commitment towards both professional and personal life. Work-life balance has become an on-going challenge in contemporary times. Though work-life balance is discussed for various decades and measured with different dimensions, this is high time to measure work-life balance in accordance with present lifestyle. Here comes the role of internet which is twisted with every human being in day to day activities. Internet without social media is unimaginable. Usage of social media results in both productive and unproductive behaviour. Therefore this is a study to measure the usage of social media in personal life and professional life on work-life balance. It is found that social media usage in professional life has more impact on work-life balance which caused due to pre-occupation with social media in workplace.


Based on the the taxonomic group determined by Chang (2009), we further investigated examined the phenogenetic relationship of I. arborescens, I. Philippinense, I. tashiroi and I. tasueshanensis in Illiciaceae by sequence analysis of internal transcribed spacer, (ITS) and morphylogy of the pollen grains. Phenogenetic analysis classified these species into two groups associated with flower color: the red flower color group and white color group. In red flower group, I. arborescens is the primitive species growing in Taiwan. With the overlapping growth region, I. arborescens and I. tasueshanensis are distributed in the Snowy Mountains region. However, a few plants in I. tasueshanensis populations, rarely and lacking the firaling and, may be categorized as I. arborescens. In white flower group, I. philippinense var. philippinense grows in the higher altitude and has appeared after the ice age in Taiwan. I. tashiroi is widely distributed in eastern Asia and significantly different from I. philippinense var. philippinense in pollen and carpel number. With the identical phenogenetic group and limited variation in morphological traits of the pollens, we propose that I. philippinense var. oblongum will be classified as the ecological type of I. tashiroi.


Transplantation of liver left lateral section (LLS) firmly established itself as a radical and effective method of treatment of advanced diffuse and unresectable focal liver diseases in pediatric patients. At the same time surgical community faced the challenge of matching the size of the adult donor's graft to the volume of the child's abdomen. Review of the literature presents historical aspects of transplantology, some approaches to measurement of the required liver parenchyma functional mass and methods to prevent complications associated with the usage of large LLS grafts in infants. In addition, the latest data on estimation of intra-abdominal pressure and development of intra-abdominal hypertension syndrome are also presented.


A study to quantify the spatial variability of physical and chemical properties of soil in a citrus farm in the department of Caldas was conducted. The particle size of soil and also the contents of nitrogen, phosphorus, potassium, calcium and magnesium and soil pH was evaluated. A total of 75 soil samples were collected and analyzed in a laboratory to determine the values of the variables described above, the Software ArcGIS® was used to estimate the variability of every variable through Kriging methodology. Two maps were created for each of the variables, a map with the maximum and minimum data set and other map considering optimal ranges of nutrients for crop growing. High estimated values of sand, medium values of silt and low values of clay were found, the highest coefficient of variation was for the silt variable with respect to chemical variables spatial variability for all variables was found, showing the phosphorus the biggest coefficient of variation. In general low contents of all variables except Nitrogen who presented estimated ranges above the optimum for growing levels were found. Those maps obtained by interpolation through 'Kriging' methodology have a great potential for designing strategies for sitespecific management.


The present study examined whether the ability of mutant p53 to block apoptosis depended on its transcriptional activity. A core domain mutant p53 (143 Val to Ala), in which two N‐terminal residues (22 and 23) essential for transactivation were also mutated (Leu to Glu and Trp to Ser, respectively), was examined. While p53 containing only the core mutation efficiently interfered with drug‐induced apoptosis, further modification at the N‐terminus abolished this blocking activity. Furthermore, expression of c‐myc, a suggested target for core mutant p53 transactivation, was elevated in the core mutant p53‐expressing cells, but was abolished in the presence of the transcription‐deficient p53 core mutant. In addition, wild‐type p53, mutated in the N‐terminus (residues 22 and 23), was unable to induce apoptosis by itself. Nevertheless, it synergized with drugs in the induction of apoptosis. This suggests that the integrity of the N‐terminus is essential for both the activity of wild‐type p53 in apoptosis and for mutant p53‐mediated block of drug‐induced apoptosis. This supports the notion that core p53 mutants act via a gain of function mechanism.


For image texture analysis,an invariant texture recognition algorithm is proposed based on Radon transform.Firstly,Radon transform is used to project the image to 1-D space,and then the projection data is transformed via a translation and scaling invariant adaptive 1-D wavelet transform,thus the feature matrix with translation and scaling invariance is derived.Multiscale analysis is employed for the feature matrix,and the energy values at different scales are proven not only to be invariant under image translation,scaling and rotation,but also to reflect the different energy distribution of the texture image at different scales.After the feature vector is availabe,support vector machine(SVM) is used for classification.Comparing with other methods simulations are given to obtain insight into the effectiveness of our method.


Paper accompanying a presentation for the 2015 University of North Texas (UNT) Student and Faculty Research Symposium on African Studies. This paper discusses a proposal to sustainably expand doctoral production and retain more doctoral graduates in Africa in university service